format-version: 1.2 data-version: releases/2023-05-31 subsetdef: 1_STAR "" subsetdef: 2_STAR "" subsetdef: 3_STAR "" subsetdef: abnormal_slim "" subsetdef: added_for_HCA "" subsetdef: attribute_slim "" subsetdef: blood_and_immune_upper_slim "" subsetdef: cell_quality "" subsetdef: common_anatomy "" subsetdef: cumbo "" subsetdef: cyclostome_subset "" subsetdef: defined_by_ordinal_series "" subsetdef: developmental_classification "" subsetdef: disposition_slim "" subsetdef: early_development "" subsetdef: efo_slim "" subsetdef: emapa_ehdaa2 "" subsetdef: eye_upper_slim "" subsetdef: functional_classification "" subsetdef: gocheck_do_not_annotate "" subsetdef: gocheck_do_not_manually_annotate "" subsetdef: goslim_agr "" subsetdef: goslim_candida "" subsetdef: goslim_chembl "" subsetdef: goslim_drosophila "" subsetdef: goslim_flybase_ribbon "" subsetdef: goslim_generic "" subsetdef: goslim_metagenomics "" subsetdef: goslim_mouse "" subsetdef: goslim_pir "" subsetdef: goslim_plant "" subsetdef: goslim_pombe "" subsetdef: goslim_synapse "" subsetdef: goslim_yeast "" subsetdef: grouping_class "" subsetdef: homology_grouping "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_gp2term "" subsetdef: http://purl.obolibrary.org/obo/valid_for_go_ontology "" subsetdef: http://purl.obolibrary.org/obo/valid_for_gocam "" subsetdef: human_reference_atlas "" subsetdef: inconsistent_with_fma "" subsetdef: location_grouping "" subsetdef: major_organ "" subsetdef: mpath_slim "" subsetdef: non_informative "" subsetdef: organ_slim "" subsetdef: pheno_slim "" subsetdef: phenotype_rcn "" subsetdef: prokaryote_subset "" subsetdef: relational_slim "" subsetdef: ro-eco "" subsetdef: RO:0002259 "" subsetdef: scalar_slim "" subsetdef: term_scheduled_for_obsoletion "" subsetdef: uberon_slim "" subsetdef: ubprop:upper_level "" subsetdef: unverified_taxonomic_grouping "" subsetdef: upper_level "" subsetdef: value_slim "" subsetdef: vertebrate_core "" synonymtypedef: ABBREVIATION "" synonymtypedef: abbreviation "" synonymtypedef: blast_name "" synonymtypedef: common_name "" synonymtypedef: COMPARATIVE_PREFERRED "" synonymtypedef: DEPRECATED "" synonymtypedef: DUBIOUS "" synonymtypedef: equivalent_name "" synonymtypedef: genbank_common_name "" synonymtypedef: Gene-based "" synonymtypedef: HOMOLOGY "" synonymtypedef: human "" synonymtypedef: HUMAN_PREFERRED "" synonymtypedef: in_part "" synonymtypedef: INCONSISTENT "" synonymtypedef: INN "" synonymtypedef: IUPAC_NAME "" synonymtypedef: LATIN "" synonymtypedef: PENDING_REVIEW "" synonymtypedef: PLURAL "" synonymtypedef: PRO-short-label "" synonymtypedef: scientific_name "" synonymtypedef: SENSU "" synonymtypedef: syngo_official_label "" synonymtypedef: synonym "" synonymtypedef: SYSTEMATIC "" synonymtypedef: systematic_synonym "" synonymtypedef: vertebrate "" ontology: fovt property_value: dc-description "None" xsd:string property_value: dc-description "These are the terms that are improted for FOVT to describe vertebrate traits." xsd:string property_value: dc-title "FuTRES Ontology of Vertebrate Traits" xsd:string property_value: dcterms-license http://creativecommons.org/publicdomain/zero/1.0/ property_value: owl:versionInfo "2023-05-31" xsd:string [Term] id: BCO:0000003 name: observing process def: "A process in which a person or machine sees or detects a material entity and selects it as worthy of observation, and which has as output an information content entity about the selected material entity." [] comment: An observing process is distinguished from a specimen collecting process in by having an information content entity as an output rather than a specimen. The information artifact may be written or recorded or just be stored in someone's head (specifically depenedent upon that person). In the context of a taxonomic inventory, an observing process may be called a sighting, which is an ad hoc reporting of, typically, a single taxon occurrence, usually motivated by rarity, individual interest in the taxon, or atypicality of circumstances. is_a: OBI:0000011 ! planned process relationship: OBI:0000293 BFO:0000040 ! has_specified_input material entity relationship: OBI:0000299 IAO:0000030 ! has_specified_output information content entity property_value: BCO:0000057 "sighting" xsd:string property_value: editor_note "This class replaces class bco_0000003, which was made obsolete because of identifier format." xsd:string property_value: editor_note "We are having conversation with OBI developers about how this term relates to OBI:assay (). Is it equivalent, broader, narrower? What does it mean to be the input to an observation." xsd:string property_value: http://purl.org/dc/elements/1.1/creator "Biocode Commons Ontology Hackathon" xsd:string property_value: IAO:0000112 "A trip camera capture of an image of a jaguar is an observation, because it is \"selected\" by the camera as worthy of obsevation simply by virtue of moving in front of the camera." xsd:string property_value: IAO:0000112 "Observing and recording the presence or absence of butterflies during a transect walk." xsd:string property_value: IAO:0000112 "Seeing three pelicans flying overhead on Christmas day and report them as part of the Christmas Bird Count." xsd:string property_value: IAO:0000114 IAO:0000125 [Term] id: BCO:0000046 name: material target of observation role def: "A role that is borne by some material entity and is realized by the material entity being the input of an observing process." [] is_a: BFO:0000023 ! role is_a: CHEBI:50906 ! role intersection_of: BFO:0000023 ! role intersection_of: BFO:0000054 BCO:0000003 ! realized in observing process relationship: BFO:0000054 BCO:0000003 ! realized in observing process property_value: editor_note "This term replaced bco_0000046, which was made obsolete because of incorrect identifier format." xsd:string property_value: http://purl.org/dc/elements/1.1/creator "Biocode Commons Ontology Hackathon" xsd:string property_value: IAO:0000112 "the role borne by a bird during a Christmas Bird Count" xsd:string property_value: IAO:0000114 IAO:0000125 [Term] id: BFO:0000001 name: entity disjoint_from: ObsoleteClass ! Obsolete Class property_value: BFO:0000179 "entity" xsd:string property_value: BFO:0000180 "Entity" xsd:string property_value: editor_note "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81" xsd:string property_value: editor_note "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000004", comment="per discussion with Barry Smith", http://www.w3.org/2000/01/rdf-schema#seeAlso="http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"} property_value: IAO:0000112 "Julius Caesar" xsd:string property_value: IAO:0000112 "the Second World War" xsd:string property_value: IAO:0000112 "Verdi’s Requiem" xsd:string property_value: IAO:0000112 "your body mass index" xsd:string property_value: IAO:0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/001-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000002 name: continuant def: "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts." [] is_a: BFO:0000001 ! entity disjoint_from: BFO:0000003 ! occurrent relationship: part_of BFO:0000002 {all_only="true"} ! continuant property_value: BFO:0000179 "continuant" xsd:string property_value: BFO:0000180 "Continuant" xsd:string property_value: editor_note "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240" xsd:string property_value: editor_note "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000007"} property_value: IAO:0000111 "continuant" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl property_value: IAO:0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000601 "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000601 "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/009-002"} property_value: IAO:0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/126-001"} property_value: IAO:0000602 "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/008-002"} property_value: IAO:0000602 "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/011-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000003 name: occurrent def: "An entity that has temporal parts and that happens, unfolds or develops through time." [] is_a: BFO:0000001 ! entity relationship: part_of BFO:0000003 {all_only="true"} ! occurrent property_value: BFO:0000179 "occurrent" xsd:string property_value: BFO:0000180 "Occurrent" xsd:string property_value: editor_note "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region" xsd:string property_value: editor_note "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players." xsd:string property_value: editor_note "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000006", comment="per discussion with Barry Smith"} property_value: editor_note "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000012"} property_value: IAO:0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/077-002"} property_value: IAO:0000601 "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: IAO:0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/108-001"} property_value: IAO:0000602 "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/079-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000004 name: independent continuant def: "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything." [] def: "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000004 {all_only="true"} ! independent continuant property_value: BFO:0000179 "ic" xsd:string property_value: BFO:0000180 "IndependentContinuant" xsd:string property_value: IAO:0000112 "a chair" xsd:string property_value: IAO:0000112 "a heart" xsd:string property_value: IAO:0000112 "a leg" xsd:string property_value: IAO:0000112 "a molecule" xsd:string property_value: IAO:0000112 "a spatial region" xsd:string property_value: IAO:0000112 "an atom" xsd:string property_value: IAO:0000112 "an orchestra." xsd:string property_value: IAO:0000112 "an organism" xsd:string property_value: IAO:0000112 "the bottom right portion of a human torso" xsd:string property_value: IAO:0000112 "the interior of your mouth" xsd:string property_value: IAO:0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000601 "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/018-002"} property_value: IAO:0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/134-001"} property_value: IAO:0000602 "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/017-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000006 name: spatial region is_a: BFO:0000141 ! immaterial entity property_value: BFO:0000179 "s-region" xsd:string property_value: BFO:0000180 "SpatialRegion" xsd:string property_value: editor_note "BFO 2 Reference: Spatial regions do not participate in processes." xsd:string property_value: editor_note "Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000002", comment="per discussion with Barry Smith"} property_value: IAO:0000600 "A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/035-001"} property_value: IAO:0000601 "All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/036-001"} property_value: IAO:0000602 "(forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/036-001"} property_value: IAO:0000602 "(forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/035-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000015 name: process def: "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t." [] def: "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} is_a: http://rs.tdwg.org/dwc/terms/Event ! Event equivalent_to: http://rs.tdwg.org/dwc/terms/Event ! Event property_value: BFO:0000179 "process" xsd:string property_value: BFO:0000180 "Process" xsd:string property_value: editor_note "BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)" xsd:string property_value: IAO:0000112 "a process of cell-division, \\ a beating of the heart" xsd:string property_value: IAO:0000112 "a process of meiosis" xsd:string property_value: IAO:0000112 "a process of sleeping" xsd:string property_value: IAO:0000112 "the course of a disease" xsd:string property_value: IAO:0000112 "the flight of a bird" xsd:string property_value: IAO:0000112 "the life of an organism" xsd:string property_value: IAO:0000112 "your process of aging." xsd:string property_value: IAO:0000602 "(iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/083-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000016 name: disposition is_a: BFO:0000017 ! realizable entity disjoint_from: BFO:0000023 ! role property_value: BFO:0000179 "disposition" xsd:string property_value: BFO:0000180 "Disposition" xsd:string property_value: editor_note "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type." xsd:string property_value: IAO:0000112 "an atom of element X has the disposition to decay to an atom of element Y" xsd:string property_value: IAO:0000112 "certain people have a predisposition to colon cancer" xsd:string property_value: IAO:0000112 "children are innately disposed to categorize objects in certain ways." xsd:string property_value: IAO:0000112 "the cell wall is disposed to filter chemicals in endocytosis and exocytosis" xsd:string property_value: IAO:0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: IAO:0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/063-002"} property_value: IAO:0000602 "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/062-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000017 name: realizable entity def: "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances." [] is_a: BFO:0000020 ! specifically dependent continuant disjoint_from: BFO:0000019 ! quality relationship: part_of BFO:0000017 {all_only="true"} ! realizable entity property_value: BFO:0000179 "realizable" xsd:string property_value: BFO:0000180 "RealizableEntity" xsd:string property_value: IAO:0000112 "the disposition of this piece of metal to conduct electricity." xsd:string property_value: IAO:0000112 "the disposition of your blood to coagulate" xsd:string property_value: IAO:0000112 "the function of your reproductive organs" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the role of this boundary to delineate where Utah and Colorado meet" xsd:string property_value: IAO:0000117 "https://orcid.org/0000-0001-8815-0078" xsd:string property_value: IAO:0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: IAO:0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/060-002"} property_value: IAO:0000602 "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/058-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000019 name: quality is_a: BFO:0000020 ! specifically dependent continuant relationship: part_of BFO:0000019 {all_only="true"} ! quality property_value: BFO:0000179 "quality" xsd:string property_value: BFO:0000180 "Quality" xsd:string property_value: IAO:0000112 "the ambient temperature of this portion of air" xsd:string property_value: IAO:0000112 "the color of a tomato" xsd:string property_value: IAO:0000112 "the length of the circumference of your waist" xsd:string property_value: IAO:0000112 "the mass of this piece of gold." xsd:string property_value: IAO:0000112 "the shape of your nose" xsd:string property_value: IAO:0000112 "the shape of your nostril" xsd:string property_value: IAO:0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: IAO:0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/105-001"} property_value: IAO:0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/055-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000020 name: specifically dependent continuant def: "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same." [] def: "b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/131-004"} def: "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} is_a: BFO:0000002 ! continuant disjoint_from: BFO:0000031 ! generically dependent continuant relationship: part_of BFO:0000020 {all_only="true"} ! specifically dependent continuant property_value: BFO:0000179 "sdc" xsd:string property_value: BFO:0000180 "SpecificallyDependentContinuant" xsd:string property_value: editor_note "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc." xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/0000005", comment="per discussion with Barry Smith"} property_value: IAO:0000111 "specifically dependent continuant" xsd:string property_value: IAO:0000112 "of one-sided specifically dependent continuants: the mass of this tomato" xsd:string property_value: IAO:0000112 "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates." xsd:string property_value: IAO:0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key" xsd:string property_value: IAO:0000112 "the disposition of this fish to decay" xsd:string property_value: IAO:0000112 "the function of this heart: to pump blood" xsd:string property_value: IAO:0000112 "the mutual dependence of proton donors and acceptors in chemical reactions [79" xsd:string property_value: IAO:0000112 "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction" xsd:string property_value: IAO:0000112 "the pink color of a medium rare piece of grilled filet mignon at its center" xsd:string property_value: IAO:0000112 "the role of being a doctor" xsd:string property_value: IAO:0000112 "the shape of this hole." xsd:string property_value: IAO:0000112 "the smell of this portion of mozzarella" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl property_value: IAO:0000602 "(iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/131-004"} property_value: IAO:0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/050-003"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000023 name: role def: "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts." [] is_a: CHEBI:50906 ! role equivalent_to: CHEBI:50906 ! role property_value: BFO:0000179 "role" xsd:string property_value: BFO:0000180 "Role" xsd:string property_value: editor_note "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives." xsd:string property_value: IAO:0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married." xsd:string property_value: IAO:0000112 "the priest role" xsd:string property_value: IAO:0000112 "the role of a boundary to demarcate two neighboring administrative territories" xsd:string property_value: IAO:0000112 "the role of a building in serving as a military target" xsd:string property_value: IAO:0000112 "the role of a stone in marking a property boundary" xsd:string property_value: IAO:0000112 "the role of subject in a clinical trial" xsd:string property_value: IAO:0000112 "the student role" xsd:string property_value: IAO:0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: IAO:0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/061-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000031 name: generically dependent continuant def: "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time." [] def: "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])" [] {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} is_a: BFO:0000002 ! continuant property_value: BFO:0000179 "gdc" xsd:string property_value: BFO:0000180 "GenericallyDependentContinuant" xsd:string property_value: IAO:0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity." xsd:string property_value: IAO:0000112 "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop" xsd:string property_value: IAO:0000112 "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule." xsd:string property_value: IAO:0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/074-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000034 name: function is_a: BFO:0000016 ! disposition property_value: BFO:0000179 "function" xsd:string property_value: BFO:0000180 "Function" xsd:string property_value: editor_note "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc." xsd:string property_value: IAO:0000112 "the function of a hammer to drive in nails" xsd:string property_value: IAO:0000112 "the function of a heart pacemaker to regulate the beating of a heart through electricity" xsd:string property_value: IAO:0000112 "the function of amylase in saliva to break down starch into sugar" xsd:string property_value: IAO:0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: IAO:0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/064-001"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000040 name: material entity def: "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time." [] is_a: BFO:0000004 ! independent continuant disjoint_from: BFO:0000141 ! immaterial entity property_value: BFO:0000179 "material" xsd:string property_value: BFO:0000180 "MaterialEntity" xsd:string property_value: editor_note "BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60" xsd:string property_value: editor_note "BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity." xsd:string property_value: editor_note "BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here." xsd:string property_value: IAO:0000111 "material entity" xsd:string property_value: IAO:0000112 "a flame" xsd:string property_value: IAO:0000112 "a forest fire" xsd:string property_value: IAO:0000112 "a human being" xsd:string property_value: IAO:0000112 "a hurricane" xsd:string property_value: IAO:0000112 "a photon" xsd:string property_value: IAO:0000112 "a puff of smoke" xsd:string property_value: IAO:0000112 "a sea wave" xsd:string property_value: IAO:0000112 "a tornado" xsd:string property_value: IAO:0000112 "an aggregate of human beings." xsd:string property_value: IAO:0000112 "an energy wave" xsd:string property_value: IAO:0000112 "an epidemic" xsd:string property_value: IAO:0000112 "the undetached arm of a human being" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ido.owl property_value: IAO:0000600 "A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: IAO:0000601 "every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000601 "Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])" xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/021-002"} property_value: IAO:0000602 "(forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/020-002"} property_value: IAO:0000602 "(forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002] " xsd:string {http://purl.obolibrary.org/obo/IAO_0010000="http://purl.obolibrary.org/obo/bfo/axiom/019-002"} property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BFO:0000141 name: immaterial entity is_a: BFO:0000004 ! independent continuant property_value: BFO:0000179 "immaterial" xsd:string property_value: BFO:0000180 "ImmaterialEntity" xsd:string property_value: editor_note "BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Term] id: BSPO:0000000 name: left side namespace: spatial def: "The side of an organism that is left of the sagittal plane." [BSPO:cjm] synonym: "left" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: left_of BSPO:0000007 ! right side relationship: starts_axis BSPO:0000017 ! left-right axis [Term] id: BSPO:0000005 name: anatomical surface namespace: spatial def: "A 2D surface of an anatomical continuant." [BSPO:cjm] comment: to be merged into CARO synonym: "surface" EXACT [] xref: FMA:24137 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000007 name: right side namespace: spatial def: "The side of an organism that is right of the sagittal plane." [BSPO:cjm, BSPO:wd] synonym: "right" EXACT [] is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000017 ! left-right axis [Term] id: BSPO:0000009 name: midsagittal plane namespace: spatial def: "Sagittal plane that divides bilateral body into equal left and right parts." [BSPO:mah] comment: only in bilaterally symmetrical organisms synonym: "median plane" RELATED [] synonym: "median sagittal plane" EXACT [FMA:74563] synonym: "midline plane" EXACT [] synonym: "midsagittal section" EXACT [] xref: FMA:74563 is_a: BSPO:0000417 ! sagittal plane [Term] id: BSPO:0000010 name: anatomical axis namespace: spatial def: "A straight line through space, intersecting an anatomical entity." [BSPO:cjm] comment: Axis directions are defined in terms of axes. xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG is_a: CARO:0000008 ! anatomical line relationship: passes_through CARO:0000000 ! anatomical entity [Term] id: BSPO:0000013 name: anterior-posterior axis namespace: spatial def: "An axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm] comment: In sponges, AP is used to indicate the direction of movement [in larval stage] (as it is in other metazoans that move, e.g., the basal bilaterians). [PM] synonym: "A-P axis" EXACT [] synonym: "anteroposterior axis" EXACT [] synonym: "AP axis" EXACT [] synonym: "cephalocaudal axis" NARROW [http://en.wikipedia.org/wiki/Anatomical_terms_of_location] synonym: "craniocaudal axis" NARROW vertebrate [] synonym: "longitudinal axis" RELATED [] synonym: "rostral/caudal" NARROW vertebrate [] synonym: "rostrocaudal axis" NARROW vertebrate [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000018 ! transverse plane relationship: approximately_perpendicular_to BSPO:0000016 ! dorsal-ventral axis relationship: orthogonal_to BSPO:0000018 ! transverse plane [Term] id: BSPO:0000015 name: proximal-distal axis namespace: spatial def: "An axis that extends from the point of attachment of a structure (proximal) to the point furthest away from the plane of attachment (distal)." [BSPO:curators, http://en.wikipedia.org/wiki/Anatomical_terms_of_location] comment: In some communities, proximal and distal are used when specifying the position of parts of elements that are contained within the body, such as gill arches or vertebral spines. In these cases, use of the classes medial-lateral axis or medial-external axis are more appropriate. synonym: "proximal/distal" EXACT [] synonym: "proximodistal" EXACT [] is_a: BSPO:0000010 ! anatomical axis [Term] id: BSPO:0000016 name: dorsal-ventral axis namespace: spatial def: "An axis that is approximately perpendicular to the anterior-posterior axis and that extends through the horizontal plane of the body." [BSPO:curators] synonym: "anterior-posterior axis" NARROW human [] synonym: "D-V axis" EXACT [] synonym: "dorsoventral axis" EXACT [] synonym: "DV axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000019 ! horizontal plane relationship: orthogonal_to BSPO:0000019 ! horizontal plane [Term] id: BSPO:0000017 name: left-right axis namespace: spatial def: "An axis that bisects an organism from left to right sides of body, through a sagittal plane." [BSPO:cjm] synonym: "dextro-sinister axis" EXACT [] synonym: "L-R axis" EXACT [] synonym: "left to right axis" EXACT [] synonym: "LR axis" EXACT [] synonym: "R-L axis" EXACT [] synonym: "right to left axis" EXACT [] synonym: "right-left axis" EXACT [] synonym: "RL axis" EXACT [] is_a: BSPO:0000010 ! anatomical axis intersection_of: BSPO:0000010 ! anatomical axis intersection_of: orthogonal_to BSPO:0000417 ! sagittal plane relationship: orthogonal_to BSPO:0000417 ! sagittal plane [Term] id: BSPO:0000018 name: transverse plane namespace: spatial def: "Anatomical plane that divides body into anterior and posterior parts." [BSPO:mah] synonym: "axial plane" EXACT [] synonym: "axial section" EXACT [] synonym: "cross-section" RELATED [] synonym: "transverse section" EXACT [] xref: FMA:12247 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000019 name: horizontal plane namespace: spatial def: "Anatomical plane that divides bilateral body into dorsal and ventral parts." [BSPO:mah] synonym: "coronal section" RELATED [] synonym: "frontal plane" EXACT [] synonym: "frontal section" RELATED [] synonym: "horizontal anatomical plane" EXACT [FMA:52810] synonym: "horizontal section" EXACT [] xref: FMA:52810 is_a: BSPO:0000400 ! anatomical plane [Term] id: BSPO:0000027 name: antero-ventral region namespace: spatial def: "Anatomical region that overlaps the anterior and ventral regions of a body or body part." [BSPO:wd] synonym: "anteroventral region " EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-06-15T01:04:59Z [Term] id: BSPO:0000028 name: postero-lateral region namespace: spatial def: "Anatomical region that overlaps the posterior and lateral regions of the body or body part." [BSPO:wd] synonym: "posterolateral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-06-15T01:06:01Z [Term] id: BSPO:0000029 name: antero-lateral region namespace: spatial def: "Anatomical region that overlaps the anterior and lateral regions of a body or body part." [BSPO:wd] synonym: "anterolateral region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000082 ! lateral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000066 ! lateral side created_by: Melissa Haendel creation_date: 2009-06-15T01:07:18Z [Term] id: BSPO:0000035 name: postero-ventral region namespace: spatial def: "Anatomical region that overlaps the posterior and ventral regions of a body or body part." [BSPO:wd] synonym: "posteroventral region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-06-15T01:08:38Z [Term] id: BSPO:0000050 name: antero-medial region namespace: spatial def: "Anatomical region that overlaps the anterior and medial regions of the body or body part." [BSPO:wd] synonym: "anteromedial region" EXACT [] is_a: BSPO:0000071 ! anterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:55:32Z [Term] id: BSPO:0000054 name: anatomical side namespace: spatial def: "An anatomical region bounded by a plane perpendicular to an axis through the middle." [BSPO:cjm] xref: FBql:00005841 is_a: BSPO:0000070 ! anatomical region [Term] id: BSPO:0000055 name: anterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure anterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW] synonym: "anterior" EXACT [] synonym: "rostral" EXACT [] xref: FBcv:0000053 xref: FBql:00005848 is_a: BSPO:0000054 ! anatomical side relationship: anterior_to BSPO:0000056 ! posterior side relationship: opposite_to BSPO:0000056 ! posterior side relationship: starts_axis BSPO:0000013 ! anterior-posterior axis [Term] id: BSPO:0000056 name: posterior side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure posterior to a transverse plane and bounded on one side by the same transverse plane." [BSPO:RW, BSPO:wd] synonym: "caudal" NARROW vertebrate [] synonym: "posterior" EXACT [] xref: FBcv:0000065 xref: FBql:00005849 is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000013 ! anterior-posterior axis relationship: posterior_to BSPO:0000055 ! anterior side [Term] id: BSPO:0000061 name: proximal side namespace: spatial synonym: "proximal" EXACT [] xref: FBcv:0000066 xref: FBql:00005852 is_a: BSPO:0000054 ! anatomical side relationship: opposite_to BSPO:0000062 ! distal side relationship: starts_axis BSPO:0000015 ! proximal-distal axis [Term] id: BSPO:0000062 name: distal side namespace: spatial def: "Anatomical side that is distally located on an organism or structure." [BSPO:wd] synonym: "distal" EXACT [] xref: FBcv:0000058 xref: FBql:00005853 is_a: BSPO:0000054 ! anatomical side relationship: distal_to BSPO:0000061 ! proximal side relationship: finishes_axis BSPO:0000015 ! proximal-distal axis [Term] id: BSPO:0000064 name: postero-medial region namespace: spatial def: "Anatomical region that overlaps the posterior and medial regions of the body or body part." [BSPO:wd] synonym: "posteromedial region" EXACT [] is_a: BSPO:0000072 ! posterior region is_a: BSPO:0000083 ! medial region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side intersection_of: overlaps BSPO:0000067 ! medial side created_by: Melissa Haendel creation_date: 2009-09-10T08:56:39Z [Term] id: BSPO:0000066 name: lateral side namespace: spatial synonym: "lateral" EXACT [] xref: FBcv:0000063 xref: FBql:00005844 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000067 name: medial side namespace: spatial comment: a point in the centre of the organism (where the left-right axis intersects the midsagittal plane) synonym: "medial" EXACT [] xref: FBcv:0000064 xref: FBql:00005847 is_a: BSPO:0000054 ! anatomical side [Term] id: BSPO:0000068 name: ventral side namespace: spatial def: "An anatomical region that is the entire part of an anatomical structure ventral to a horizontal plane and bounded on one side by the same horizontal plane." [BSPO:RW, BSPO:wd] synonym: "ventral" EXACT [] xref: FBcv:0000070 xref: FBql:00005843 is_a: BSPO:0000054 ! anatomical side relationship: finishes_axis BSPO:0000016 ! dorsal-ventral axis [Term] id: BSPO:0000070 name: anatomical region namespace: spatial def: "A 3D region in space without well-defined compartmental boundaries; for example, the dorsal region of an ectoderm." [BSPO:cjm] comment: to be merged into CARO xref: FBql:00005841 is_a: CARO:0000003 ! connected anatomical structure [Term] id: BSPO:0000071 name: anterior region namespace: spatial def: "Anatomical region anteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000055 ! anterior side relationship: overlaps BSPO:0000055 ! anterior side [Term] id: BSPO:0000072 name: posterior region namespace: spatial def: "Anatomical region posteriorly located on the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000056 ! posterior side relationship: overlaps BSPO:0000056 ! posterior side [Term] id: BSPO:0000077 name: proximal region namespace: spatial def: "Anatomical region proximally located on the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000061 ! proximal side relationship: overlaps BSPO:0000061 ! proximal side [Term] id: BSPO:0000078 name: distal region namespace: spatial def: "Anatomical region distally located on the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000062 ! distal side relationship: overlaps BSPO:0000062 ! distal side [Term] id: BSPO:0000082 name: lateral region namespace: spatial def: "Anatomical region laterally located on the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000066 ! lateral side relationship: overlaps BSPO:0000066 ! lateral side [Term] id: BSPO:0000083 name: medial region namespace: spatial def: "Anatomical region medially located on the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000067 ! medial side relationship: overlaps BSPO:0000067 ! medial side [Term] id: BSPO:0000084 name: ventral region namespace: spatial def: "Anatomical region ventrally located on the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000070 ! anatomical region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000068 ! ventral side relationship: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000085 name: ventro-lateral region namespace: spatial def: "Anatomical region that overlaps the ventral and lateral regions of a body or body part." [BSPO:wd] comment: This is an example of a composition of two axis positions. synonym: "ventrolateral region" EXACT [] xref: FBql:00005846 is_a: BSPO:0000082 ! lateral region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000066 ! lateral side intersection_of: overlaps BSPO:0000068 ! ventral side [Term] id: BSPO:0000112 name: ventro-medial region namespace: spatial def: "The region corresponding to the ventral region of the entity, towards the midline." [BSPO:wd] synonym: "medioventral region" EXACT [] synonym: "ventromedial region" EXACT [] is_a: BSPO:0000083 ! medial region is_a: BSPO:0000084 ! ventral region intersection_of: BSPO:0000070 ! anatomical region intersection_of: overlaps BSPO:0000067 ! medial side intersection_of: overlaps BSPO:0000068 ! ventral side created_by: Melissa Haendel creation_date: 2009-09-10T08:57:54Z [Term] id: BSPO:0000196 name: medial-external axis namespace: spatial def: "An anatomical axis that extends from the center of the body outwards or externally." [BSPO:curators] comment: The medial-external axis could apply to a sphere-shaped body. synonym: "proximal-distal axis" RELATED [] is_a: BSPO:0000010 ! anatomical axis created_by: wasila.dahdul creation_date: 2013-07-02T11:21:42Z [Term] id: BSPO:0000371 name: anterior surface namespace: spatial def: "Anatomical surface that is located on the anterior side of the body or body part." [BSPO:wd] xref: FBql:00005848 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000055 ! anterior side relationship: surface_of BSPO:0000055 ! anterior side [Term] id: BSPO:0000372 name: posterior surface namespace: spatial def: "Anatomical surface that is located on the posterior side of the body or body part." [BSPO:wd] xref: FBql:00005849 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000056 ! posterior side relationship: surface_of BSPO:0000056 ! posterior side [Term] id: BSPO:0000377 name: proximal surface namespace: spatial def: "Anatomical surface that is located on the proximal side of the body or body part." [BSPO:wd] xref: FBql:00005852 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000061 ! proximal side relationship: surface_of BSPO:0000061 ! proximal side [Term] id: BSPO:0000378 name: distal surface namespace: spatial def: "Anatomical surface that is located on the distal side of the body or body part." [BSPO:wd] xref: FBql:00005853 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000062 ! distal side relationship: surface_of BSPO:0000062 ! distal side [Term] id: BSPO:0000382 name: lateral surface namespace: spatial def: "Anatomical surface that located on the lateral side of the body or body part." [BSPO:wd] xref: FBql:00005844 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000066 ! lateral side relationship: surface_of BSPO:0000066 ! lateral side [Term] id: BSPO:0000383 name: medial surface namespace: spatial def: "Anatomical surface that located on the medial side of the body or body part." [BSPO:wd] xref: FBql:00005847 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000067 ! medial side relationship: surface_of BSPO:0000067 ! medial side [Term] id: BSPO:0000384 name: ventral surface namespace: spatial def: "Anatomical surface that is located on the ventral side of the body or body part." [BSPO:wd] xref: FBql:00005843 is_a: BSPO:0000005 ! anatomical surface intersection_of: BSPO:0000005 ! anatomical surface intersection_of: surface_of BSPO:0000068 ! ventral side relationship: surface_of BSPO:0000068 ! ventral side [Term] id: BSPO:0000400 name: anatomical plane namespace: spatial def: "A flat 2D plane intersecting an anatomical continuant, dividing it into two adjacent portions." [BSPO:cjm] comment: These anatomical sections are applicable to most bilaterally symmetrical animals, but bipedal animals such as humans have more complex usage of these terms. For example, in post-embryonic humans a coronal plane is vertical and a transverse plane is horizontal, but for embryos and quadrupeds a coronal plane is horizontal and a transverse plane is vertical. synonym: "anatomical cross-section" EXACT [] synonym: "anatomical section" EXACT [] synonym: "cross-section" RELATED [] synonym: "plane" EXACT [] synonym: "section" EXACT [] xref: FMA:242982 is_a: CARO:0000010 ! anatomical boundary [Term] id: BSPO:0000417 name: sagittal plane namespace: spatial def: "Anatomical plane that divides a bilateral body into left and right parts, not necessarily of even size." [BSPO:cjm, BSPO:DOS, BSPO:mah] synonym: "left/right plane" EXACT [] synonym: "median plane" EXACT [] synonym: "sagittal section" EXACT [] xref: FMA:11361 is_a: BSPO:0000010 ! anatomical axis is_a: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0000400 ! anatomical plane intersection_of: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis intersection_of: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis intersection_of: orthogonal_to BSPO:0000017 ! left-right axis relationship: BSPO:0001102 BSPO:0000013 ! parallel to anterior-posterior axis relationship: BSPO:0001102 BSPO:0000016 ! parallel to dorsal-ventral axis relationship: orthogonal_to BSPO:0000017 ! left-right axis [Term] id: BSPO:0001001 name: medial-lateral axis namespace: spatial def: "An axis that extends from the center of organism to one or other side." [BSPO:cjm] comment: Properly, the ML axis is a half axis; practically, its usage is less clumsy and less linguistically biased than "left-right". The terms may still be used relatively to describe locations along the LR axis. The gills are medial to the operculum, but lateral to the heart. synonym: "M-L axis" EXACT [] synonym: "medio-lateral axis" EXACT [] synonym: "mediolateral axis" EXACT [] synonym: "ML axis" EXACT [] synonym: "proximal-distal axis " RELATED [] xref: http://upload.wikimedia.org/wikipedia/commons/3/34/Anatomical_Directions_and_Axes.JPG is_a: BSPO:0000196 ! medial-external axis [Term] id: CARO:0000000 name: anatomical entity namespace: spatial def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [CAROC:Brownsville2014] def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [CARO:MAH] comment: Following BFO, material anatomical entities may have immaterial parts (the lumen of your stomach is part of your stomach). The granularity limit follows the limits set by the Gene Ontology on the granularity limit for GO:cellular_component. Note that substances produced by an organism (sweat, feaces, urine) do not need to be part of an organism to qualify as an anatomical structure. is_a: BFO:0000004 ! independent continuant [Term] id: CARO:0000003 name: anatomical structure name: connected anatomical structure namespace: spatial def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CC:DOS] comment: Note that the definition does not say 'generated exclusively by the co-ordinated expression of the organism's own genome', so this is still valid for cases where normal morphogenesis requires the actions of a facultative symbiont, or some looser dependency such as the a requirement for the presence of gut flora for normal gut development. is_a: CARO:0000006 ! material anatomical entity [Term] id: CARO:0000006 name: material anatomical entity namespace: spatial def: "An anatomical entity that has mass." [CC:DOS] is_a: CARO:0000000 ! anatomical entity disjoint_from: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000007 name: immaterial anatomical entity namespace: spatial def: "An anatomical entity that has no mass." [CC:DOS] def: "Anatomical entity that has no mass." [] is_a: BFO:0000141 ! immaterial entity is_a: CARO:0000000 ! anatomical entity [Term] id: CARO:0000008 name: anatomical line namespace: spatial def: "A one dimensional, immaterial anatomical entity." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0000010 name: anatomical boundary namespace: spatial def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CC:DOS] is_a: CARO:0000007 ! immaterial anatomical entity [Term] id: CARO:0001001 name: neuron projection bundle def: "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." [] is_a: CARO:0000006 ! material anatomical entity [Term] id: CARO:0001010 name: organism or virus or viroid def: "Material anatomical entity that is a member of an individual species or is a viral or viroid particle." [] is_a: BFO:0000040 ! material entity property_value: IAO:0000117 "Melissa Haendel" xsd:string [Term] id: CARO:0010000 name: multicellular anatomical structure def: "An anatomical structure that has more than one cell as a part." [] is_a: CARO:0000003 ! connected anatomical structure property_value: IAO:0000117 "djs93" xsd:string [Term] id: CHEBI:10545 name: electron namespace: chebi_ontology def: "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." [] subset: 3_STAR synonym: "beta" RELATED [IUPAC] synonym: "beta(-)" RELATED [ChEBI] synonym: "beta-particle" RELATED [IUPAC] synonym: "e" RELATED [IUPAC] synonym: "e(-)" RELATED [UniProt] synonym: "e-" RELATED [KEGG_COMPOUND] synonym: "electron" EXACT [KEGG_COMPOUND] synonym: "electron" EXACT IUPAC_NAME [IUPAC] synonym: "electron" EXACT [ChEBI] synonym: "Elektron" RELATED [ChEBI] synonym: "negatron" RELATED [IUPAC] xref: KEGG:C05359 xref: PMID:21614077 {source="Europe PMC"} xref: Wikipedia:Electron is_a: CHEBI:36338 ! lepton property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.000548579903" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string [Term] id: CHEBI:131927 name: dicarboxylic acids and O-substituted derivatives namespace: chebi_ontology def: "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." [] subset: 3_STAR synonym: "dicarboxylic acids and derivatives" RELATED [ChEBI] is_a: CHEBI:36586 ! carbonyl compound [Term] id: CHEBI:132153 name: hyaluronate namespace: chebi_ontology def: "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." [] subset: 3_STAR synonym: "hyaluronan" RELATED [UniProt] synonym: "hyaluronate polyanion" RELATED [ChEBI] is_a: CHEBI:61469 ! polyanionic polymer is_a: CHEBI:63551 ! carbohydrate acid derivative anion relationship: is_conjugate_base_of CHEBI:16336 ! hyaluronic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H20NO11)n.H2O" xsd:string [Term] id: CHEBI:136889 name: 5beta steroid namespace: chebi_ontology def: "Any steroid that has beta-configuration at position 5." [] subset: 3_STAR synonym: "5beta steroids" RELATED [ChEBI] synonym: "5beta-steroid" RELATED [ChEBI] synonym: "5beta-steroids" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:138103 name: inorganic acid namespace: chebi_ontology def: "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." [] subset: 3_STAR synonym: "inorganic acids" RELATED [ChEBI] synonym: "mineral acid" RELATED [ChEBI] synonym: "mineral acids" RELATED [ChEBI] xref: Wikipedia:Mineral_acid is_a: CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:138366 name: bile acids namespace: chebi_ontology def: "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." [] subset: 3_STAR is_a: CHEBI:25384 ! monocarboxylic acid is_a: CHEBI:35350 ! hydroxy steroid is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:138675 name: gas molecular entity namespace: chebi_ontology def: "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." [] subset: 3_STAR synonym: "gas molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entities" RELATED [ChEBI] synonym: "gaseous molecular entity" RELATED [ChEBI] xref: Wikipedia:https\://en.wikipedia.org/wiki/Gas is_a: CHEBI:33579 ! main group molecular entity [Term] id: CHEBI:13941 name: carbamate namespace: chebi_ontology subset: 3_STAR synonym: "Carbamat" RELATED [ChEBI] synonym: "carbamate" EXACT [UniProt] synonym: "carbamate" EXACT IUPAC_NAME [IUPAC] synonym: "carbamate ion" RELATED [ChemIDplus] synonym: "carbamic acid, ion(1-)" RELATED [ChemIDplus] synonym: "Karbamat" RELATED [ChEBI] xref: Beilstein:3903503 {source="Beilstein"} xref: CAS:302-11-4 {source="ChemIDplus"} xref: Gmelin:239604 {source="Gmelin"} is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:28616 ! carbamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.03212" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.00910" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([O-])=O" xsd:string [Term] id: CHEBI:142163 name: 24G7 epitope namespace: chebi_ontology def: "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." [] subset: 3_STAR is_a: CHEBI:24433 ! group relationship: has_role CHEBI:53000 ! epitope property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H6N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "134.136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "134.04801" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*" xsd:string [Term] id: CHEBI:15339 name: acceptor namespace: chebi_ontology alt_id: CHEBI:13699 alt_id: CHEBI:2377 def: "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." [] subset: 3_STAR synonym: "A" RELATED [KEGG_COMPOUND] synonym: "accepteur" RELATED [ChEBI] synonym: "Acceptor" EXACT [KEGG_COMPOUND] synonym: "Akzeptor" RELATED [ChEBI] synonym: "Hydrogen-acceptor" RELATED [KEGG_COMPOUND] synonym: "Oxidized donor" RELATED [KEGG_COMPOUND] xref: KEGG:C00028 xref: KEGG:C16722 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:15355 name: acetylcholine namespace: chebi_ontology alt_id: CHEBI:12686 alt_id: CHEBI:13715 alt_id: CHEBI:22197 alt_id: CHEBI:2416 alt_id: CHEBI:40559 def: "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." [] subset: 3_STAR synonym: "2-acetyloxy-N,N,N-trimethylethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "ACETYLCHOLINE" EXACT [PDBeChem] synonym: "Acetylcholine" EXACT [KEGG_COMPOUND] synonym: "acetylcholine" EXACT [UniProt] synonym: "ACh" RELATED [ChemIDplus] synonym: "Azetylcholin" RELATED [ChEBI] synonym: "choline acetate" RELATED [ChemIDplus] synonym: "O-Acetylcholine" RELATED [KEGG_COMPOUND] xref: Beilstein:1764436 {source="ChemIDplus"} xref: CAS:51-84-3 {source="KEGG COMPOUND"} xref: CAS:51-84-3 {source="ChemIDplus"} xref: Drug_Central:65 {source="DrugCentral"} xref: DrugBank:DB03128 xref: Gmelin:326108 {source="Gmelin"} xref: KEGG:C01996 xref: LINCS:LSM-5888 xref: PDBeChem:ACH xref: PMID:14764638 {source="Europe PMC"} xref: PMID:15014918 {source="Europe PMC"} xref: PMID:15231705 {source="Europe PMC"} xref: PMID:15361288 {source="Europe PMC"} xref: PMID:18050502 {source="Europe PMC"} xref: PMID:18407448 {source="Europe PMC"} xref: PMID:19255787 {source="Europe PMC"} xref: PMID:20963497 {source="Europe PMC"} xref: PMID:21130809 {source="Europe PMC"} xref: PMID:21246223 {source="Europe PMC"} xref: PMID:21545631 {source="Europe PMC"} xref: PMID:21601579 {source="Europe PMC"} xref: Wikipedia:Acetylcholine is_a: CHEBI:35287 ! acylcholine is_a: CHEBI:47622 ! acetate ester relationship: has_role CHEBI:24621 ! hormone relationship: has_role CHEBI:25512 ! neurotransmitter relationship: has_role CHEBI:35620 ! vasodilator agent relationship: has_role CHEBI:38325 ! muscarinic agonist relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C7H16NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OIPILFWXSMYKGL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "146.20748" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "146.11756" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)OCC[N+](C)(C)C" xsd:string [Term] id: CHEBI:15366 name: acetic acid namespace: chebi_ontology alt_id: CHEBI:22169 alt_id: CHEBI:2387 alt_id: CHEBI:40486 def: "A simple monocarboxylic acid containing two carbons." [] subset: 3_STAR synonym: "ACETIC ACID" EXACT [PDBeChem] synonym: "Acetic acid" EXACT [KEGG_COMPOUND] synonym: "acetic acid" EXACT IUPAC_NAME [IUPAC] synonym: "acide acetique" RELATED [ChemIDplus] synonym: "AcOH" RELATED [ChEBI] synonym: "CH3-COOH" RELATED [IUPAC] synonym: "CH3CO2H" RELATED [ChEBI] synonym: "E 260" RELATED [ChEBI] synonym: "E-260" RELATED [ChEBI] synonym: "E260" RELATED [ChEBI] synonym: "Essigsaeure" RELATED [ChEBI] synonym: "Ethanoic acid" RELATED [KEGG_COMPOUND] synonym: "ethoic acid" RELATED [ChEBI] synonym: "Ethylic acid" RELATED [ChemIDplus] synonym: "HOAc" RELATED [ChEBI] synonym: "INS No. 260" RELATED [ChEBI] synonym: "MeCO2H" RELATED [ChEBI] synonym: "MeCOOH" RELATED [ChEBI] synonym: "Methanecarboxylic acid" RELATED [ChemIDplus] xref: Beilstein:506007 {source="Beilstein"} xref: CAS:64-19-7 {source="ChemIDplus"} xref: CAS:64-19-7 {source="NIST Chemistry WebBook"} xref: CAS:64-19-7 {source="KEGG COMPOUND"} xref: Drug_Central:4211 {source="DrugCentral"} xref: Gmelin:1380 {source="Gmelin"} xref: HMDB:HMDB0000042 xref: KEGG:C00033 xref: KEGG:D00010 xref: KNApSAcK:C00001176 xref: LIPID_MAPS_instance:LMFA01010002 {source="LIPID MAPS"} xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PDBeChem:ACY xref: PMID:12005138 {source="Europe PMC"} xref: PMID:15107950 {source="Europe PMC"} xref: PMID:16630552 {source="Europe PMC"} xref: PMID:16774200 {source="Europe PMC"} xref: PMID:17190852 {source="Europe PMC"} xref: PMID:19416101 {source="Europe PMC"} xref: PMID:19469536 {source="Europe PMC"} xref: PMID:22153255 {source="Europe PMC"} xref: PMID:22173419 {source="Europe PMC"} xref: PPDB:1333 xref: Reaxys:506007 {source="Reaxys"} xref: Wikipedia:Acetic_acid is_a: CHEBI:25384 ! monocarboxylic acid relationship: has_role CHEBI:48356 ! protic solvent relationship: has_role CHEBI:64049 ! food acidity regulator relationship: has_role CHEBI:65256 ! antimicrobial food preservative relationship: has_role CHEBI:83056 ! Daphnia magna metabolite relationship: is_conjugate_acid_of CHEBI:30089 ! acetate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.05200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.02113" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(O)=O" xsd:string [Term] id: CHEBI:15379 name: dioxygen namespace: chebi_ontology alt_id: CHEBI:10745 alt_id: CHEBI:13416 alt_id: CHEBI:23833 alt_id: CHEBI:25366 alt_id: CHEBI:30491 alt_id: CHEBI:44742 alt_id: CHEBI:7860 subset: 3_STAR synonym: "[OO]" RELATED [MolBase] synonym: "dioxygen" EXACT IUPAC_NAME [IUPAC] synonym: "dioxygene" RELATED [ChEBI] synonym: "Disauerstoff" RELATED [ChEBI] synonym: "E 948" RELATED [ChEBI] synonym: "E-948" RELATED [ChEBI] synonym: "E948" RELATED [ChEBI] synonym: "molecular oxygen" RELATED [ChEBI] synonym: "O2" RELATED [UniProt] synonym: "O2" RELATED [IUPAC] synonym: "O2" RELATED [KEGG_COMPOUND] synonym: "Oxygen" RELATED [KEGG_COMPOUND] synonym: "OXYGEN MOLECULE" RELATED [PDBeChem] xref: CAS:7782-44-7 {source="NIST Chemistry WebBook"} xref: CAS:7782-44-7 {source="ChemIDplus"} xref: CAS:7782-44-7 {source="KEGG COMPOUND"} xref: Gmelin:485 {source="Gmelin"} xref: HMDB:HMDB0001377 xref: KEGG:C00007 xref: KEGG:D00003 xref: MetaCyc:OXYGEN-MOLECULE xref: MolBase:750 xref: PDBeChem:OXY xref: PMID:10906528 {source="Europe PMC"} xref: PMID:16977326 {source="Europe PMC"} xref: PMID:18210929 {source="Europe PMC"} xref: PMID:18638417 {source="Europe PMC"} xref: PMID:19840863 {source="Europe PMC"} xref: PMID:7710549 {source="Europe PMC"} xref: PMID:9463773 {source="Europe PMC"} xref: Wikipedia:Oxygen is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:25362 ! elemental molecule is_a: CHEBI:33263 ! diatomic oxygen relationship: has_role CHEBI:27027 ! micronutrient relationship: has_role CHEBI:33893 ! reagent relationship: has_role CHEBI:35472 ! anti-inflammatory drug relationship: has_role CHEBI:63248 ! oxidising agent relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:77974 ! food packaging gas relationship: is_conjugate_base_of CHEBI:29793 ! hydridodioxygen(1+) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "31.998" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=O" xsd:string [Term] id: CHEBI:15693 name: aldose namespace: chebi_ontology alt_id: CHEBI:13755 alt_id: CHEBI:22305 alt_id: CHEBI:2561 def: "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." [] subset: 3_STAR synonym: "Aldose" EXACT [KEGG_COMPOUND] synonym: "aldoses" RELATED [ChEBI] synonym: "an aldose" RELATED [UniProt] xref: KEGG:C01370 xref: Wikipedia:Aldose is_a: CHEBI:35381 ! monosaccharide property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4O2(CH2O)n" xsd:string [Term] id: CHEBI:15841 name: polypeptide namespace: chebi_ontology alt_id: CHEBI:14860 alt_id: CHEBI:8314 def: "A peptide containing ten or more amino acid residues." [] subset: 3_STAR synonym: "polipeptido" RELATED [ChEBI] synonym: "Polypeptid" RELATED [ChEBI] synonym: "Polypeptide" EXACT [KEGG_COMPOUND] synonym: "polypeptides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00403 is_a: CHEBI:16670 ! peptide is_a: CHEBI:33839 ! macromolecule property_value: http://purl.obolibrary.org/obo/chebi/formula "C4H6N2O3R2(C2H2NOR)n" xsd:string [Term] id: CHEBI:15986 name: polynucleotide namespace: chebi_ontology alt_id: CHEBI:13672 alt_id: CHEBI:14859 alt_id: CHEBI:8312 def: "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." [] subset: 3_STAR synonym: "Polynucleotide" EXACT [KEGG_COMPOUND] synonym: "polynucleotides" RELATED [ChEBI] xref: KEGG:C00419 is_a: CHEBI:33695 ! information biomacromolecule is_a: CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_part CHEBI:50319 ! nucleotide residue property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C5H8O6PR)n.C10H17O10PR2" xsd:string [Term] id: CHEBI:16134 name: ammonia namespace: chebi_ontology alt_id: CHEBI:13405 alt_id: CHEBI:13406 alt_id: CHEBI:13407 alt_id: CHEBI:13771 alt_id: CHEBI:22533 alt_id: CHEBI:44269 alt_id: CHEBI:44284 alt_id: CHEBI:44404 alt_id: CHEBI:7434 def: "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." [] subset: 3_STAR synonym: "[NH3]" RELATED [MolBase] synonym: "AMMONIA" EXACT [PDBeChem] synonym: "Ammonia" EXACT [KEGG_COMPOUND] synonym: "ammonia" EXACT IUPAC_NAME [IUPAC] synonym: "ammoniac" RELATED [ChEBI] synonym: "Ammoniak" RELATED [ChemIDplus] synonym: "amoniaco" RELATED [ChEBI] synonym: "azane" EXACT IUPAC_NAME [IUPAC] synonym: "NH3" RELATED [KEGG_COMPOUND] synonym: "NH3" RELATED [UniProt] synonym: "NH3" RELATED [IUPAC] synonym: "R-717" RELATED [ChEBI] synonym: "spirit of hartshorn" RELATED [ChemIDplus] xref: Beilstein:3587154 {source="Beilstein"} xref: CAS:7664-41-7 {source="ChemIDplus"} xref: CAS:7664-41-7 {source="NIST Chemistry WebBook"} xref: CAS:7664-41-7 {source="KEGG COMPOUND"} xref: Drug_Central:4625 {source="DrugCentral"} xref: Gmelin:79 {source="Gmelin"} xref: HMDB:HMDB0000051 xref: KEGG:C00014 xref: KEGG:D02916 xref: KNApSAcK:C00007267 xref: MetaCyc:AMMONIA xref: MolBase:930 xref: PDBeChem:NH3 xref: PMID:110589 {source="Europe PMC"} xref: PMID:11139349 {source="Europe PMC"} xref: PMID:11540049 {source="Europe PMC"} xref: PMID:11746427 {source="Europe PMC"} xref: PMID:11783653 {source="Europe PMC"} xref: PMID:13753780 {source="Europe PMC"} xref: PMID:14663195 {source="Europe PMC"} xref: PMID:15092448 {source="Europe PMC"} xref: PMID:15094021 {source="Europe PMC"} xref: PMID:15554424 {source="Europe PMC"} xref: PMID:15969015 {source="Europe PMC"} xref: PMID:16008360 {source="Europe PMC"} xref: PMID:16050680 {source="Europe PMC"} xref: PMID:16348008 {source="Europe PMC"} xref: PMID:16349403 {source="Europe PMC"} xref: PMID:16614889 {source="Europe PMC"} xref: PMID:16664306 {source="Europe PMC"} xref: PMID:16842901 {source="Europe PMC"} xref: PMID:17025297 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17569513 {source="Europe PMC"} xref: PMID:17737668 {source="Europe PMC"} xref: PMID:18670398 {source="Europe PMC"} xref: PMID:22002069 {source="Europe PMC"} xref: PMID:22081570 {source="Europe PMC"} xref: PMID:22088435 {source="Europe PMC"} xref: PMID:22100291 {source="Europe PMC"} xref: PMID:22130175 {source="Europe PMC"} xref: PMID:22150211 {source="Europe PMC"} xref: PMID:22240068 {source="Europe PMC"} xref: PMID:22290316 {source="Europe PMC"} xref: PMID:22342082 {source="Europe PMC"} xref: PMID:22385337 {source="Europe PMC"} xref: PMID:22443779 {source="Europe PMC"} xref: PMID:22560242 {source="Europe PMC"} xref: Reaxys:3587154 {source="Reaxys"} xref: Wikipedia:Ammonia is_a: CHEBI:138675 ! gas molecular entity is_a: CHEBI:35107 ! azane is_a: CHEBI:37176 ! mononuclear parent hydride relationship: has_role CHEBI:50910 ! neurotoxin relationship: has_role CHEBI:59740 ! nucleophilic reagent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77941 ! EC 3.5.1.4 (amidase) inhibitor relationship: has_role CHEBI:78433 ! refrigerant relationship: is_conjugate_acid_of CHEBI:29337 ! azanide relationship: is_conjugate_base_of CHEBI:28938 ! ammonium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.03056" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]N([H])[H]" xsd:string [Term] id: CHEBI:16189 name: sulfate namespace: chebi_ontology alt_id: CHEBI:15135 alt_id: CHEBI:45687 alt_id: CHEBI:9335 def: "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." [] subset: 3_STAR synonym: "[SO4](2-)" RELATED [IUPAC] synonym: "SO4(2-)" RELATED [IUPAC] synonym: "Sulfate" EXACT [KEGG_COMPOUND] synonym: "sulfate" EXACT [UniProt] synonym: "sulfate" EXACT IUPAC_NAME [IUPAC] synonym: "Sulfate anion(2-)" RELATED [HMDB] synonym: "Sulfate dianion" RELATED [HMDB] synonym: "SULFATE ION" RELATED [PDBeChem] synonym: "Sulfate(2-)" RELATED [HMDB] synonym: "Sulfuric acid ion(2-)" RELATED [HMDB] synonym: "sulphate" RELATED [ChEBI] synonym: "sulphate ion" RELATED [ChEBI] synonym: "tetraoxidosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3648446 {source="Beilstein"} xref: CAS:14808-79-8 {source="ChemIDplus"} xref: CAS:14808-79-8 {source="NIST Chemistry WebBook"} xref: Gmelin:2120 {source="Gmelin"} xref: HMDB:HMDB0001448 xref: KEGG:C00059 xref: KEGG:D05963 xref: MetaCyc:SULFATE xref: PDBeChem:SO4 xref: PMID:11200094 {source="Europe PMC"} xref: PMID:11452993 {source="Europe PMC"} xref: PMID:11581495 {source="Europe PMC"} xref: PMID:11798107 {source="Europe PMC"} xref: PMID:12166931 {source="Europe PMC"} xref: PMID:12668033 {source="Europe PMC"} xref: PMID:14597181 {source="Europe PMC"} xref: PMID:15093386 {source="Europe PMC"} xref: PMID:15984785 {source="Europe PMC"} xref: PMID:16186560 {source="Europe PMC"} xref: PMID:16345535 {source="Europe PMC"} xref: PMID:16347366 {source="Europe PMC"} xref: PMID:16348007 {source="Europe PMC"} xref: PMID:16483812 {source="Europe PMC"} xref: PMID:16534979 {source="Europe PMC"} xref: PMID:16656509 {source="Europe PMC"} xref: PMID:16742508 {source="Europe PMC"} xref: PMID:16742518 {source="Europe PMC"} xref: PMID:17120760 {source="Europe PMC"} xref: PMID:17420092 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17709180 {source="Europe PMC"} xref: PMID:18398178 {source="Europe PMC"} xref: PMID:18815700 {source="Europe PMC"} xref: PMID:18846414 {source="Europe PMC"} xref: PMID:19047345 {source="Europe PMC"} xref: PMID:19244483 {source="Europe PMC"} xref: PMID:19544990 {source="Europe PMC"} xref: PMID:19628332 {source="Europe PMC"} xref: PMID:19812358 {source="Europe PMC"} xref: PMID:30398859 {source="Europe PMC"} xref: Reaxys:3648446 {source="Reaxys"} xref: Wikipedia:Sulfate is_a: CHEBI:33482 ! sulfur oxoanion is_a: CHEBI:48154 ! sulfur oxide is_a: CHEBI:79388 ! divalent inorganic anion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:45696 ! hydrogensulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06360" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95283" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S([O-])(=O)=O" xsd:string [Term] id: CHEBI:16336 name: hyaluronic acid namespace: chebi_ontology alt_id: CHEBI:14412 alt_id: CHEBI:24622 alt_id: CHEBI:24623 alt_id: CHEBI:5772 def: "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." [] subset: 3_STAR synonym: "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n" RELATED [ChEBI] synonym: "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n" RELATED [KEGG_COMPOUND] synonym: "acide hyaluronique" RELATED [ChEBI] synonym: "acido hialuronico" RELATED [ChEBI] synonym: "hyaluronan" RELATED [ChEBI] synonym: "Hyaluronic acid" EXACT [KEGG_COMPOUND] synonym: "Hyaluronsaeure" RELATED [ChEBI] xref: Beilstein:8538277 {source="Beilstein"} xref: CAS:9004-61-9 {source="KEGG COMPOUND"} xref: CAS:9004-61-9 {source="ChemIDplus"} xref: HMDB:HMDB0010366 xref: KEGG:C00518 xref: KEGG:D08043 xref: KEGG:G10505 xref: PMID:11122186 {source="Europe PMC"} xref: PMID:18056362 {source="Europe PMC"} xref: PMID:18290544 {source="Europe PMC"} xref: Reaxys:8187837 {source="Reaxys"} xref: Wikipedia:Hyaluronan is_a: CHEBI:37395 ! mucopolysaccharide is_a: CHEBI:72813 ! exopolysaccharide relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:132153 ! hyaluronate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C14H21NO12)n" xsd:string [Term] id: CHEBI:16541 name: protein polypeptide chain namespace: chebi_ontology alt_id: CHEBI:8526 def: "A naturally occurring polypeptide synthesized at the ribosome." [] subset: 3_STAR synonym: "a protein" RELATED [UniProt] synonym: "polypeptide chain" RELATED [ChEBI] synonym: "Protein" RELATED [KEGG_COMPOUND] synonym: "protein polypeptide chains" RELATED [ChEBI] xref: KEGG:C00017 is_a: CHEBI:15841 ! polypeptide relationship: has_part CHEBI:33700 ! proteinogenic amino-acid residue [Term] id: CHEBI:16646 name: carbohydrate namespace: chebi_ontology alt_id: CHEBI:15131 alt_id: CHEBI:23008 alt_id: CHEBI:9318 def: "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." [] subset: 3_STAR synonym: "a carbohydrate" RELATED [UniProt] synonym: "carbohidrato" RELATED [IUPAC] synonym: "carbohidratos" RELATED [IUPAC] synonym: "carbohydrate" EXACT IUPAC_NAME [IUPAC] synonym: "carbohydrates" EXACT IUPAC_NAME [IUPAC] synonym: "glucide" RELATED [ChEBI] synonym: "glucides" RELATED [ChEBI] synonym: "glucido" RELATED [ChEBI] synonym: "glucidos" RELATED [ChEBI] synonym: "hydrates de carbone" RELATED [ChEBI] synonym: "Kohlenhydrat" RELATED [ChEBI] synonym: "Kohlenhydrate" RELATED [ChEBI] synonym: "saccharide" RELATED [IUPAC] synonym: "saccharides" RELATED [IUPAC] synonym: "saccharidum" RELATED [ChEBI] xref: Wikipedia:Carbohydrate is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16670 name: peptide namespace: chebi_ontology alt_id: CHEBI:14753 alt_id: CHEBI:25906 alt_id: CHEBI:7990 def: "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." [] subset: 3_STAR synonym: "Peptid" RELATED [ChEBI] synonym: "Peptide" EXACT [KEGG_COMPOUND] synonym: "peptides" EXACT IUPAC_NAME [IUPAC] synonym: "peptido" RELATED [ChEBI] synonym: "peptidos" RELATED [ChEBI] xref: KEGG:C00012 is_a: CHEBI:37622 ! carboxamide is_a: CHEBI:50047 ! organic amino compound relationship: has_part CHEBI:33708 ! amino-acid residue relationship: is_tautomer_of CHEBI:60466 ! peptide zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "(C2H2NOR)nC2H3NOR" xsd:string [Term] id: CHEBI:166902 name: noradrenaline(1+) namespace: chebi_ontology subset: 2_STAR synonym: "noradrenaline" RELATED [UniProt] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:33569 ! noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC(=C1O)O)C(C[NH3+])O" xsd:string [Term] id: CHEBI:167559 name: glycan namespace: chebi_ontology def: "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." [] subset: 3_STAR synonym: "glycans" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives [Term] id: CHEBI:16765 name: tryptamine namespace: chebi_ontology alt_id: CHEBI:15274 alt_id: CHEBI:27161 alt_id: CHEBI:46157 alt_id: CHEBI:9767 def: "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." [] subset: 3_STAR synonym: "1H-indole-3-ethanamine" RELATED [NIST_Chemistry_WebBook] synonym: "2-(1H-INDOL-3-YL)ETHANAMINE" RELATED [PDBeChem] synonym: "2-(1H-indol-3-yl)ethanamine" EXACT IUPAC_NAME [IUPAC] synonym: "2-(3-indolyl)ethylamine" RELATED [ChemIDplus] synonym: "3-(2-Aminoethyl)indole" RELATED [KEGG_COMPOUND] synonym: "Tryptamine" EXACT [KEGG_COMPOUND] xref: Beilstein:125513 {source="Beilstein"} xref: CAS:61-54-1 {source="ChemIDplus"} xref: CAS:61-54-1 {source="NIST Chemistry WebBook"} xref: CAS:61-54-1 {source="KEGG COMPOUND"} xref: DrugBank:DB08653 xref: Gmelin:603448 {source="Gmelin"} xref: HMDB:HMDB0000303 xref: KEGG:C00398 xref: KNApSAcK:C00001434 xref: MetaCyc:TRYPTAMINE xref: PDBeChem:TSS xref: PMID:16126914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24345948 {source="Europe PMC"} xref: PMID:24558969 {source="Europe PMC"} xref: Reaxys:125513 {source="Reaxys"} xref: Wikipedia:Tryptamine is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:38631 ! aminoalkylindole is_a: CHEBI:38958 ! indole alkaloid is_a: CHEBI:64365 ! aralkylamino compound relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:57887 ! tryptaminium property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "160.21570" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "160.10005" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCCc1c[nH]c2ccccc12" xsd:string [Term] id: CHEBI:16990 name: bilirubin IXalpha namespace: chebi_ontology alt_id: CHEBI:13898 alt_id: CHEBI:22870 alt_id: CHEBI:3099 def: "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." [] subset: 3_STAR synonym: "1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid" RELATED [ChemIDplus] synonym: "2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid" RELATED [ChemIDplus] synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" RELATED [IUPAC] synonym: "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid" EXACT IUPAC_NAME [IUPAC] synonym: "8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione" RELATED [JCBN] synonym: "Bilirubin" RELATED [KEGG_COMPOUND] synonym: "bilirubin" EXACT IUPAC_NAME [IUPAC] synonym: "bilirubin(Z,Z)" RELATED [ChEBI] synonym: "bilirubin-IXalpha" RELATED [ChEBI] xref: Beilstein:74376 {source="Beilstein"} xref: CAS:635-65-4 {source="KEGG COMPOUND"} xref: CAS:635-65-4 {source="ChemIDplus"} xref: Gmelin:411033 {source="Gmelin"} xref: HMDB:HMDB0000054 xref: KEGG:C00486 xref: KNApSAcK:C00029828 xref: MetaCyc:BILIRUBIN xref: PDBeChem:BLR xref: PMID:12799017 {source="Europe PMC"} xref: PMID:18442622 {source="Europe PMC"} xref: PMID:23763371 {source="Europe PMC"} xref: PMID:23768684 {source="Europe PMC"} xref: PMID:30224965 {source="Europe PMC"} xref: PMID:8605219 {source="Europe PMC"} xref: PMID:9587403 {source="Europe PMC"} xref: Reaxys:74376 {source="Reaxys"} xref: Wikipedia:Bilirubin is_a: CHEBI:35692 ! dicarboxylic acid is_a: CHEBI:36735 ! biladienes relationship: has_part CHEBI:142163 ! 24G7 epitope relationship: has_role CHEBI:22586 ! antioxidant relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:57977 ! bilirubin(2-) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H36N4O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "584.673" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "584.26348" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\\C=C2/NC(=O)C(C=C)=C2C)N1" xsd:string [Term] id: CHEBI:16991 name: deoxyribonucleic acid namespace: chebi_ontology alt_id: CHEBI:13302 alt_id: CHEBI:21123 alt_id: CHEBI:33698 alt_id: CHEBI:4291 def: "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." [] subset: 3_STAR synonym: "(Deoxyribonucleotide)m" RELATED [KEGG_COMPOUND] synonym: "(Deoxyribonucleotide)n" RELATED [KEGG_COMPOUND] synonym: "(Deoxyribonucleotide)n+m" RELATED [KEGG_COMPOUND] synonym: "Deoxyribonucleic acid" EXACT [KEGG_COMPOUND] synonym: "deoxyribonucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "deoxyribonucleic acids" RELATED [ChEBI] synonym: "Desoxyribonukleinsaeure" RELATED [ChEBI] synonym: "desoxyribose nucleic acid" RELATED [ChemIDplus] synonym: "DNA" RELATED [UniProt] synonym: "DNA" RELATED [KEGG_COMPOUND] synonym: "DNA" RELATED [IUPAC] synonym: "DNAn" RELATED [KEGG_COMPOUND] synonym: "DNAn+1" RELATED [KEGG_COMPOUND] synonym: "DNS" RELATED [ChEBI] synonym: "thymus nucleic acid" RELATED [ChEBI] xref: CAS:9007-49-2 {source="ChemIDplus"} xref: CAS:9007-49-2 {source="KEGG COMPOUND"} xref: KEGG:C00039 is_a: CHEBI:33696 ! nucleic acid relationship: has_part CHEBI:33793 ! canonical deoxyribonucleoside residue relationship: has_part CHEBI:50298 ! canonical deoxyribonucleotide residue relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite [Term] id: CHEBI:17087 name: ketone namespace: chebi_ontology alt_id: CHEBI:13427 alt_id: CHEBI:13646 alt_id: CHEBI:24974 alt_id: CHEBI:6127 alt_id: CHEBI:8742 def: "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." [] subset: 3_STAR synonym: "a ketone" RELATED [UniProt] synonym: "cetone" RELATED [ChEBI] synonym: "Keton" RELATED [ChEBI] synonym: "Ketone" EXACT [KEGG_COMPOUND] synonym: "ketones" EXACT IUPAC_NAME [IUPAC] synonym: "ketones" RELATED [ChEBI] synonym: "R-CO-R'" RELATED [KEGG_COMPOUND] xref: KEGG:C01450 xref: Wikipedia:Ketone is_a: CHEBI:36586 ! carbonyl compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "COR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "28.010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C([*])=O" xsd:string [Term] id: CHEBI:17089 name: glycoprotein namespace: chebi_ontology alt_id: CHEBI:14349 alt_id: CHEBI:5481 alt_id: CHEBI:5493 def: "A compound in which a carbohydrate component is covalently bound to a protein component." [] subset: 3_STAR synonym: "a glycoprotein" RELATED [UniProt] synonym: "glicoproteina" RELATED [ChEBI] synonym: "glicoproteinas" RELATED [ChEBI] synonym: "Glycoprotein" EXACT [KEGG_COMPOUND] synonym: "glycoproteine" RELATED [ChEBI] synonym: "glycoproteines" RELATED [ChEBI] synonym: "glycoproteins" EXACT IUPAC_NAME [IUPAC] synonym: "Glykoprotein" RELATED [ChEBI] synonym: "Glykoproteine" RELATED [ChEBI] xref: KEGG:C00326 is_a: CHEBI:33837 ! conjugated protein is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:17234 name: glucose namespace: chebi_ontology alt_id: CHEBI:14313 alt_id: CHEBI:24277 alt_id: CHEBI:33929 alt_id: CHEBI:5418 def: "An aldohexose used as a source of energy and metabolic intermediate." [] subset: 3_STAR synonym: "DL-glucose" RELATED [ChEBI] synonym: "Glc" RELATED [JCBN] synonym: "gluco-hexose" EXACT IUPAC_NAME [IUPAC] synonym: "Glucose" EXACT [KEGG_COMPOUND] synonym: "glucose" EXACT IUPAC_NAME [IUPAC] synonym: "Glukose" RELATED [ChEBI] xref: CAS:50-99-7 {source="KEGG COMPOUND"} xref: KEGG:C00293 xref: Wikipedia:Glucose is_a: CHEBI:33917 ! aldohexose relationship: has_role CHEBI:78675 ! fundamental metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H12O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "180.15588" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "180.06339" xsd:string [Term] id: CHEBI:17544 name: hydrogencarbonate namespace: chebi_ontology alt_id: CHEBI:13363 alt_id: CHEBI:22863 alt_id: CHEBI:40961 alt_id: CHEBI:5589 def: "The carbon oxoanion resulting from the removal of a proton from carbonic acid." [] subset: 3_STAR synonym: "[CO2(OH)](-)" RELATED [IUPAC] synonym: "Acid carbonate" RELATED [KEGG_COMPOUND] synonym: "Bicarbonate" RELATED [KEGG_COMPOUND] synonym: "BICARBONATE ION" RELATED [PDBeChem] synonym: "HCO3(-)" RELATED [IUPAC] synonym: "HCO3-" RELATED [KEGG_COMPOUND] synonym: "hydrogen carbonate" RELATED [PDBeChem] synonym: "hydrogen(trioxidocarbonate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "Hydrogencarbonate" EXACT [KEGG_COMPOUND] synonym: "hydrogencarbonate" EXACT [UniProt] synonym: "hydrogencarbonate" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogencarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentrioxocarbonate(IV)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidodioxidocarbonate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3903504 {source="Beilstein"} xref: CAS:71-52-3 {source="ChemIDplus"} xref: Gmelin:49249 {source="Gmelin"} xref: HMDB:HMDB0000595 xref: KEGG:C00288 xref: MetaCyc:HCO3 xref: PDBeChem:BCT xref: PMID:17215880 {source="Europe PMC"} xref: PMID:17505962 {source="Europe PMC"} xref: PMID:18439416 {source="Europe PMC"} xref: PMID:28732801 {source="Europe PMC"} xref: PMID:29150416 {source="Europe PMC"} xref: PMID:29460248 {source="Europe PMC"} xref: PMID:29466234 {source="Europe PMC"} xref: PMID:4208463 {source="Europe PMC"} xref: Wikipedia:Bicarbonate is_a: CHEBI:35604 ! carbon oxoanion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:41609 ! carbonate relationship: is_conjugate_base_of CHEBI:28976 ! carbonic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "61.01684" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "60.99312" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([O-])=O" xsd:string [Term] id: CHEBI:17891 name: donor namespace: chebi_ontology alt_id: CHEBI:14202 alt_id: CHEBI:4697 def: "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." [] subset: 3_STAR synonym: "Donator" RELATED [ChEBI] synonym: "donneur" RELATED [ChEBI] synonym: "Donor" EXACT [KEGG_COMPOUND] xref: KEGG:C01351 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:18059 name: lipid namespace: chebi_ontology alt_id: CHEBI:14517 alt_id: CHEBI:25054 alt_id: CHEBI:6486 def: "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." [] subset: 3_STAR synonym: "Lipid" EXACT [KEGG_COMPOUND] synonym: "lipids" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C01356 is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:18085 name: glycosaminoglycan namespace: chebi_ontology alt_id: CHEBI:14361 alt_id: CHEBI:24398 alt_id: CHEBI:5495 def: "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." [] subset: 3_STAR synonym: "glicosaminoglicano" RELATED [IUPAC] synonym: "Glycosaminoglycan" EXACT [KEGG_COMPOUND] synonym: "glycosaminoglycan" EXACT IUPAC_NAME [IUPAC] synonym: "glycosaminoglycane" RELATED [IUPAC] synonym: "glycosaminoglycans" RELATED [ChEBI] synonym: "Glykosaminoglykan" RELATED [ChEBI] xref: KEGG:C02545 xref: Wikipedia:Glycosaminoglycan is_a: CHEBI:22506 ! aminoglycan [Term] id: CHEBI:18133 name: hexose namespace: chebi_ontology alt_id: CHEBI:14399 alt_id: CHEBI:24590 alt_id: CHEBI:5709 def: "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." [] subset: 3_STAR synonym: "Hexose" EXACT [KEGG_COMPOUND] synonym: "hexoses" RELATED [ChEBI] synonym: "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/" RELATED [GlyTouCan] xref: GlyGen:G70994MS xref: GlyTouCan:G70994MS xref: KEGG:C00738 is_a: CHEBI:35381 ! monosaccharide [Term] id: CHEBI:18154 name: polysaccharide namespace: chebi_ontology alt_id: CHEBI:14864 alt_id: CHEBI:26205 alt_id: CHEBI:8322 def: "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." [] subset: 3_STAR synonym: "Glycan" RELATED [KEGG_COMPOUND] synonym: "Glycane" RELATED [ChEBI] synonym: "glycans" RELATED [IUPAC] synonym: "Glykan" RELATED [ChEBI] synonym: "Glykane" RELATED [ChEBI] synonym: "polisacarido" RELATED [ChEBI] synonym: "polisacaridos" RELATED [IUPAC] synonym: "Polysaccharide" EXACT [KEGG_COMPOUND] synonym: "polysaccharides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00420 is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:18282 name: nucleobase namespace: chebi_ontology alt_id: CHEBI:13873 alt_id: CHEBI:25598 alt_id: CHEBI:2995 def: "That part of DNA or RNA that may be involved in pairing." [] subset: 3_STAR synonym: "Base" RELATED [KEGG_COMPOUND] synonym: "nucleobases" RELATED [ChEBI] xref: KEGG:C00701 xref: Wikipedia:Nucleobase is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:18357 name: (R)-noradrenaline namespace: chebi_ontology alt_id: CHEBI:1 alt_id: CHEBI:14668 alt_id: CHEBI:25592 alt_id: CHEBI:258884 alt_id: CHEBI:43725 def: "The R-enantiomer of noradrenaline." [] subset: 3_STAR synonym: "(-)-arterenol" RELATED [ChemIDplus] synonym: "(-)-noradrenaline" RELATED [IUPHAR] synonym: "(-)-norepinephrine" RELATED [ChemIDplus] synonym: "(R)-(-)-norepinephrine" RELATED [ChemIDplus] synonym: "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol" RELATED [ChemIDplus] synonym: "(R)-norepinephrine" RELATED [ChemIDplus] synonym: "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol" RELATED [KEGG_COMPOUND] synonym: "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] synonym: "Arterenol" RELATED [KEGG_COMPOUND] synonym: "L-Noradrenaline" RELATED [KEGG_COMPOUND] synonym: "L-NOREPINEPHRINE" RELATED [PDBeChem] synonym: "Noradrenaline" RELATED [KEGG_COMPOUND] synonym: "norepinefrina" RELATED INN [ChEBI] synonym: "Norepinephrine" RELATED [KEGG_COMPOUND] synonym: "norepinephrine" RELATED INN [ChemIDplus] synonym: "norepinephrine" RELATED INN [WHO_MedNet] synonym: "norepinephrinum" RELATED INN [ChEBI] xref: Beilstein:2804840 {source="Beilstein"} xref: Beilstein:4231961 {source="ChemIDplus"} xref: CAS:51-41-2 {source="ChemIDplus"} xref: CAS:51-41-2 {source="KEGG COMPOUND"} xref: Drug_Central:1960 {source="DrugCentral"} xref: DrugBank:DB00368 xref: HMDB:HMDB0000216 xref: KEGG:C00547 xref: KEGG:D00076 xref: KNApSAcK:C00001424 xref: PDBeChem:LNR xref: Reaxys:2804840 {source="Reaxys"} xref: Wikipedia:Norepinephrine is_a: CHEBI:33569 ! noradrenaline relationship: has_role CHEBI:25512 ! neurotransmitter relationship: has_role CHEBI:35524 ! sympathomimetic agent relationship: has_role CHEBI:35569 ! alpha-adrenergic agonist relationship: has_role CHEBI:50514 ! vasoconstrictor agent relationship: has_role CHEBI:75771 ! mouse metabolite relationship: is_conjugate_base_of CHEBI:72587 ! (R)-noradrenaline(1+) relationship: is_enantiomer_of CHEBI:33571 ! (S)-noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17780" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@H](O)c1ccc(O)c(O)c1" xsd:string [Term] id: CHEBI:18367 name: phosphate(3-) namespace: chebi_ontology alt_id: CHEBI:14791 alt_id: CHEBI:45024 alt_id: CHEBI:7793 def: "A phosphate ion that is the conjugate base of hydrogenphosphate." [] subset: 3_STAR synonym: "[PO4](3-)" RELATED [IUPAC] synonym: "Orthophosphate" RELATED [KEGG_COMPOUND] synonym: "Phosphate" RELATED [KEGG_COMPOUND] synonym: "phosphate" EXACT IUPAC_NAME [IUPAC] synonym: "PHOSPHATE ION" RELATED [PDBeChem] synonym: "PO4(3-)" RELATED [IUPAC] synonym: "tetraoxidophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "tetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3903772 {source="Beilstein"} xref: CAS:14265-44-2 {source="KEGG COMPOUND"} xref: CAS:14265-44-2 {source="ChemIDplus"} xref: Gmelin:1997 {source="Gmelin"} xref: KEGG:C00009 xref: PDBeChem:PO4 {source="ChEBI"} xref: Reaxys:3903772 {source="Reaxys"} is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79387 ! trivalent inorganic anion relationship: is_conjugate_base_of CHEBI:43474 ! hydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-K" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "94.97136" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "94.95507" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]P([O-])([O-])=O" xsd:string [Term] id: CHEBI:20664 name: 5beta-cholane namespace: chebi_ontology subset: 3_STAR synonym: "5beta-cholane" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:2048472 {source="Beilstein"} is_a: CHEBI:35519 ! cholane property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-OBUPQJQESA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC" xsd:string [Term] id: CHEBI:22221 name: acyl group namespace: chebi_ontology def: "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." [] subset: 3_STAR synonym: "acyl group" EXACT [IUPAC] synonym: "acyl groups" RELATED [ChEBI] synonym: "alkanoyl" EXACT IUPAC_NAME [IUPAC] synonym: "alkanoyl group" RELATED [ChEBI] synonym: "groupe acyle" RELATED [IUPAC] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:22314 name: alkali metal atom namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal" RELATED [ChEBI] synonym: "alkali metals" EXACT IUPAC_NAME [IUPAC] synonym: "Alkalimetall" RELATED [ChEBI] synonym: "Alkalimetalle" RELATED [ChEBI] synonym: "metal alcalin" RELATED [ChEBI] synonym: "metal alcalino" RELATED [ChEBI] synonym: "metales alcalinos" RELATED [ChEBI] synonym: "metaux alcalins" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom is_a: CHEBI:33521 ! metal atom is_a: CHEBI:33559 ! s-block element atom [Term] id: CHEBI:22315 name: alkaloid namespace: chebi_ontology def: "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." [] subset: 3_STAR synonym: "alcaloide" RELATED [ChEBI] synonym: "alcaloides" RELATED [ChEBI] synonym: "Alkaloid" EXACT [ChEBI] synonym: "Alkaloide" RELATED [ChEBI] synonym: "alkaloids" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Alkaloid is_a: CHEBI:35352 ! organonitrogen compound relationship: has_role CHEBI:25212 ! metabolite [Term] id: CHEBI:22506 name: aminoglycan namespace: chebi_ontology subset: 3_STAR synonym: "aminoglycans" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:65212 ! polysaccharide derivative [Term] id: CHEBI:22563 name: anion namespace: chebi_ontology def: "A monoatomic or polyatomic species having one or more elementary charges of the electron." [] subset: 3_STAR synonym: "Anion" EXACT [ChEBI] synonym: "anion" EXACT IUPAC_NAME [IUPAC] synonym: "anion" EXACT [ChEBI] synonym: "Anionen" RELATED [ChEBI] synonym: "aniones" RELATED [ChEBI] synonym: "anions" RELATED [IUPAC] is_a: CHEBI:24870 ! ion [Term] id: CHEBI:22586 name: antioxidant namespace: chebi_ontology def: "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." [] subset: 3_STAR synonym: "antioxidants" RELATED [ChEBI] synonym: "antioxydant" RELATED [ChEBI] synonym: "antoxidant" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22695 name: base namespace: chebi_ontology def: "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." [] subset: 3_STAR synonym: "Base" EXACT [ChEBI] synonym: "base" EXACT [ChEBI] synonym: "base" EXACT IUPAC_NAME [IUPAC] synonym: "Base1" RELATED [KEGG_COMPOUND] synonym: "Base2" RELATED [KEGG_COMPOUND] synonym: "Basen" RELATED [ChEBI] synonym: "bases" RELATED [ChEBI] synonym: "Nucleobase" RELATED [KEGG_COMPOUND] xref: KEGG:C00701 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:22728 name: benzopyrrole namespace: chebi_ontology subset: 3_STAR synonym: "benzopyrroles" RELATED [ChEBI] is_a: CHEBI:27171 ! organic heterobicyclic compound is_a: CHEBI:38101 ! organonitrogen heterocyclic compound is_a: CHEBI:38180 ! polycyclic heteroarene [Term] id: CHEBI:22868 name: bile salt namespace: chebi_ontology def: "A sodium salt of the conjugate of any bile acid with either glycine or taurine." [] subset: 3_STAR synonym: "Bile acid" RELATED [KEGG_COMPOUND] synonym: "bile salts" RELATED [ChEBI] xref: KEGG:C01558 is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:38700 ! organic sodium salt [Term] id: CHEBI:23004 name: carbamoyl group namespace: chebi_ontology def: "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." [] subset: 3_STAR synonym: "-C(O)NH2" RELATED [ChEBI] synonym: "-CONH2" RELATED [IUPAC] synonym: "aminocarbonyl" RELATED [IUPAC] synonym: "carbamoyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbamyl" RELATED [ChEBI] synonym: "carbamyl group" RELATED [ChEBI] synonym: "carboxamide" RELATED [IUPAC] xref: PMID:24168430 {source="Europe PMC"} is_a: CHEBI:27207 ! univalent carboacyl group relationship: is_substituent_group_from CHEBI:28616 ! carbamic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2NO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.03272" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.01364" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(N)=O" xsd:string [Term] id: CHEBI:23019 name: carbonyl group namespace: chebi_ontology subset: 3_STAR synonym: ">C=O" RELATED [IUPAC] synonym: "carbonyl" EXACT IUPAC_NAME [IUPAC] synonym: "carbonyl group" EXACT [ChEBI] synonym: "carbonyl group" EXACT [UniProt] is_a: CHEBI:51422 ! organodiyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "28.01010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "27.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=C(*)*" xsd:string [Term] id: CHEBI:23357 name: cofactor namespace: chebi_ontology def: "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." [] subset: 3_STAR synonym: "cofactor" EXACT [IUPAC] synonym: "cofactors" EXACT IUPAC_NAME [IUPAC] xref: Wikipedia:Cofactor_(biochemistry) is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:23367 name: molecular entity namespace: chebi_ontology def: "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." [] subset: 3_STAR synonym: "entidad molecular" RELATED [IUPAC] synonym: "entidades moleculares" RELATED [IUPAC] synonym: "entite moleculaire" RELATED [IUPAC] synonym: "molecular entities" RELATED [IUPAC] synonym: "molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "molekulare Entitaet" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:23449 name: cyclic peptide namespace: chebi_ontology subset: 3_STAR synonym: "cyclic peptides" RELATED [ChEBI] synonym: "Cyclopeptid" RELATED [ChEBI] synonym: "peptide cyclique" RELATED [IUPAC] synonym: "peptido ciclico" RELATED [IUPAC] synonym: "Zyklopeptid" RELATED [ChEBI] is_a: CHEBI:16670 ! peptide [Term] id: CHEBI:23888 name: drug namespace: chebi_ontology def: "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." [] subset: 3_STAR synonym: "drugs" RELATED [ChEBI] synonym: "medicine" RELATED [ChEBI] is_a: CHEBI:52217 ! pharmaceutical [Term] id: CHEBI:23906 name: monoatomic cation namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic cations" RELATED [ChEBI] is_a: CHEBI:24867 ! monoatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:23924 name: enzyme inhibitor namespace: chebi_ontology def: "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." [] subset: 3_STAR synonym: "enzyme inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "enzyme inhibitors" RELATED [ChEBI] synonym: "inhibidor enzimatico" RELATED [ChEBI] synonym: "inhibidores enzimaticos" RELATED [ChEBI] synonym: "inhibiteur enzymatique" RELATED [ChEBI] synonym: "inhibiteurs enzymatiques" RELATED [ChEBI] is_a: CHEBI:35222 ! inhibitor is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:24384 name: glycogens namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:37163 ! glucan [Term] id: CHEBI:24431 name: chemical entity namespace: chebi_ontology def: "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." [] subset: 3_STAR synonym: "chemical entity" EXACT [UniProt] is_a: BFO:0000040 ! material entity [Term] id: CHEBI:24432 name: biological role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a biological context." [] subset: 3_STAR synonym: "biological function" RELATED [ChEBI] is_a: BFO:0000023 ! role is_a: CHEBI:50906 ! role [Term] id: CHEBI:24433 name: group namespace: chebi_ontology def: "A defined linked collection of atoms or a single atom within a molecular entity." [] subset: 3_STAR synonym: "group" EXACT IUPAC_NAME [IUPAC] synonym: "groupe" RELATED [IUPAC] synonym: "grupo" RELATED [IUPAC] synonym: "grupos" RELATED [IUPAC] synonym: "Gruppe" RELATED [ChEBI] synonym: "Rest" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity relationship: has_part CHEBI:33250 ! atom [Term] id: CHEBI:24532 name: organic heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of carbon and at least of one other element." [] subset: 3_STAR synonym: "organic heterocycle" RELATED [ChEBI] synonym: "organic heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33832 ! organic cyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:24533 name: heterodetic cyclic peptide namespace: chebi_ontology def: "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." [] subset: 3_STAR synonym: "heterodetic cyclic peptide" EXACT IUPAC_NAME [IUPAC] synonym: "heterodetic cyclic peptides" RELATED [ChEBI] synonym: "peptide cyclique heterodetique" RELATED [IUPAC] synonym: "peptido ciclico heterodetico" RELATED [IUPAC] is_a: CHEBI:23449 ! cyclic peptide [Term] id: CHEBI:24621 name: hormone namespace: chebi_ontology def: "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." [] subset: 3_STAR synonym: "endocrine" RELATED [ChEBI] synonym: "hormones" RELATED [ChEBI] is_a: CHEBI:33280 ! molecular messenger is_a: CHEBI:48705 ! agonist [Term] id: CHEBI:24651 name: hydroxides namespace: chebi_ontology def: "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." [] subset: 3_STAR is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:43176 ! hydroxy group [Term] id: CHEBI:24663 name: hydroxy-5beta-cholanic acid namespace: chebi_ontology def: "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." [] subset: 3_STAR synonym: "hydroxy-5beta-cholanic acids" RELATED [ChEBI] is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:36248 ! 5beta-cholanic acids relationship: has_functional_parent CHEBI:36238 ! 5beta-cholanic acid [Term] id: CHEBI:24828 name: indoles namespace: chebi_ontology def: "Any compound containing an indole skeleton." [] subset: 3_STAR is_a: CHEBI:22728 ! benzopyrrole [Term] id: CHEBI:24833 name: oxoacid namespace: chebi_ontology def: "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [] subset: 3_STAR synonym: "oxacids" RELATED [ChEBI] synonym: "oxiacids" RELATED [ChEBI] synonym: "oxo acid" RELATED [ChEBI] synonym: "oxoacid" EXACT IUPAC_NAME [IUPAC] synonym: "oxoacids" EXACT IUPAC_NAME [IUPAC] synonym: "oxy-acids" RELATED [ChEBI] synonym: "oxyacids" RELATED [ChEBI] is_a: CHEBI:24651 ! hydroxides relationship: has_role CHEBI:39141 ! Bronsted acid [Term] id: CHEBI:24834 name: inorganic anion namespace: chebi_ontology subset: 3_STAR synonym: "inorganic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36914 ! inorganic ion [Term] id: CHEBI:24835 name: inorganic molecular entity namespace: chebi_ontology def: "A molecular entity that contains no carbon." [] subset: 3_STAR synonym: "anorganische Verbindungen" RELATED [ChEBI] synonym: "inorganic compounds" RELATED [ChEBI] synonym: "inorganic entity" RELATED [ChEBI] synonym: "inorganic molecular entities" RELATED [ChEBI] synonym: "inorganics" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:24836 name: inorganic oxide namespace: chebi_ontology subset: 3_STAR synonym: "inorganic oxides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25741 ! oxide [Term] id: CHEBI:24866 name: salt namespace: chebi_ontology def: "A salt is an assembly of cations and anions." [] subset: 3_STAR synonym: "ionic compound" RELATED [ChEBI] synonym: "ionic compounds" RELATED [ChEBI] synonym: "sal" RELATED [ChEBI] synonym: "sales" RELATED [ChEBI] synonym: "salt" EXACT IUPAC_NAME [IUPAC] synonym: "salts" RELATED [ChEBI] synonym: "Salz" RELATED [ChEBI] synonym: "Salze" RELATED [ChEBI] synonym: "sel" RELATED [ChEBI] synonym: "sels" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_part CHEBI:22563 ! anion relationship: has_part CHEBI:36916 ! cation [Term] id: CHEBI:24867 name: monoatomic ion namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:33238 ! monoatomic entity [Term] id: CHEBI:24868 name: organic salt namespace: chebi_ontology subset: 3_STAR synonym: "organic salts" RELATED [ChEBI] synonym: "organisches Salz" RELATED [ChEBI] is_a: CHEBI:24866 ! salt [Term] id: CHEBI:24870 name: ion namespace: chebi_ontology def: "A molecular entity having a net electric charge." [] subset: 3_STAR synonym: "Ion" EXACT [ChEBI] synonym: "ion" EXACT IUPAC_NAME [IUPAC] synonym: "ion" EXACT [ChEBI] synonym: "Ionen" RELATED [ChEBI] synonym: "iones" RELATED [ChEBI] synonym: "ions" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:25046 name: linear tetrapyrrole namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:26932 ! tetrapyrrole [Term] id: CHEBI:25212 name: metabolite namespace: chebi_ontology alt_id: CHEBI:26619 alt_id: CHEBI:35220 def: "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." [] subset: 3_STAR synonym: "metabolite" EXACT IUPAC_NAME [IUPAC] synonym: "metabolites" RELATED [ChEBI] synonym: "primary metabolites" RELATED [ChEBI] synonym: "secondary metabolites" RELATED [ChEBI] is_a: CHEBI:52206 ! biochemical role [Term] id: CHEBI:25213 name: metal cation namespace: chebi_ontology subset: 3_STAR synonym: "a metal cation" RELATED [UniProt] synonym: "metal cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:25362 name: elemental molecule namespace: chebi_ontology def: "A molecule all atoms of which have the same atomic number." [] subset: 3_STAR synonym: "homoatomic molecule" RELATED [ChEBI] synonym: "homoatomic molecules" RELATED [ChEBI] is_a: CHEBI:25367 ! molecule is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:25367 name: molecule namespace: chebi_ontology def: "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." [] subset: 3_STAR synonym: "molecula" RELATED [IUPAC] synonym: "molecule" EXACT [IUPAC] synonym: "molecules" RELATED [IUPAC] synonym: "Molekuel" RELATED [ChEBI] synonym: "neutral molecular compounds" RELATED [IUPAC] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:25375 name: monoamine molecular messenger namespace: chebi_ontology def: "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [] subset: 3_STAR synonym: "monamines" RELATED [ChEBI] synonym: "monoamines" RELATED [ChEBI] is_a: CHEBI:63534 ! monoamine relationship: has_role CHEBI:33280 ! molecular messenger [Term] id: CHEBI:25384 name: monocarboxylic acid namespace: chebi_ontology def: "An oxoacid containing a single carboxy group." [] subset: 3_STAR synonym: "monocarboxylic acids" RELATED [ChEBI] is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35757 ! monocarboxylic acid anion [Term] id: CHEBI:25414 name: monoatomic monocation namespace: chebi_ontology subset: 3_STAR synonym: "monoatomic monocations" RELATED [ChEBI] synonym: "monovalent inorganic cations" RELATED [ChEBI] is_a: CHEBI:23906 ! monoatomic cation property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*+]" xsd:string [Term] id: CHEBI:25512 name: neurotransmitter namespace: chebi_ontology def: "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." [] subset: 3_STAR synonym: "neurotransmitters" RELATED [ChEBI] xref: Wikipedia:Neurotransmitter is_a: CHEBI:33280 ! molecular messenger [Term] id: CHEBI:25555 name: nitrogen atom namespace: chebi_ontology subset: 3_STAR synonym: "7N" RELATED [IUPAC] synonym: "azote" RELATED [IUPAC] synonym: "N" RELATED [IUPAC] synonym: "nitrogen" EXACT IUPAC_NAME [IUPAC] synonym: "nitrogen" RELATED [ChEBI] synonym: "nitrogeno" RELATED [ChEBI] synonym: "Stickstoff" RELATED [ChEBI] xref: WebElements:N is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "14.007" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string [Term] id: CHEBI:25585 name: nonmetal atom namespace: chebi_ontology subset: 3_STAR synonym: "Nichtmetall" RELATED [ChEBI] synonym: "Nichtmetalle" RELATED [ChEBI] synonym: "no metal" RELATED [ChEBI] synonym: "no metales" RELATED [ChEBI] synonym: "non-metal" RELATED [ChEBI] synonym: "non-metaux" RELATED [ChEBI] synonym: "nonmetal" EXACT IUPAC_NAME [IUPAC] synonym: "nonmetal" RELATED [ChEBI] synonym: "nonmetals" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:25696 name: organic anion namespace: chebi_ontology def: "Any organic ion with a net negative charge." [] subset: 3_STAR synonym: "organic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:25699 ! organic ion [Term] id: CHEBI:25697 name: organic cation namespace: chebi_ontology def: "Any organic ion with a net positive charge." [] subset: 3_STAR synonym: "organic cations" RELATED [ChEBI] is_a: CHEBI:25699 ! organic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:25699 name: organic ion namespace: chebi_ontology subset: 3_STAR synonym: "organic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:25704 name: organic sulfate namespace: chebi_ontology def: "Compounds of the general formula SO3HOR where R is an organyl group" [] subset: 3_STAR synonym: "organic sulfates" RELATED [ChEBI] is_a: CHEBI:26820 ! sulfates relationship: is_conjugate_acid_of CHEBI:58958 ! organosulfate oxoanion [Term] id: CHEBI:25741 name: oxide namespace: chebi_ontology def: "An oxide is a chemical compound of oxygen with other chemical elements." [] subset: 3_STAR synonym: "oxide" EXACT [ChEBI] synonym: "oxides" RELATED [ChEBI] is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:25805 name: oxygen atom namespace: chebi_ontology subset: 3_STAR synonym: "8O" RELATED [IUPAC] synonym: "O" RELATED [IUPAC] synonym: "oxigeno" RELATED [ChEBI] synonym: "oxygen" EXACT IUPAC_NAME [IUPAC] synonym: "oxygen" RELATED [ChEBI] synonym: "oxygene" RELATED [ChEBI] synonym: "Sauerstoff" RELATED [ChEBI] xref: KEGG:C00007 xref: WebElements:O is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QVGXLLKOCUKJST-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O]" xsd:string [Term] id: CHEBI:25806 name: oxygen molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "oxygen molecular entities" RELATED [ChEBI] synonym: "oxygen molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:25805 ! oxygen atom [Term] id: CHEBI:25905 name: peptide hormone namespace: chebi_ontology def: "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." [] subset: 3_STAR synonym: "peptide hormones" RELATED [ChEBI] synonym: "polypeptide hormone" RELATED [ChEBI] is_a: CHEBI:16670 ! peptide relationship: has_role CHEBI:24621 ! hormone [Term] id: CHEBI:26020 name: phosphate namespace: chebi_ontology def: "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." [] subset: 3_STAR synonym: "phosphates" EXACT IUPAC_NAME [IUPAC] synonym: "phosphates" RELATED [ChEBI] is_a: CHEBI:26079 ! phosphoric acid derivative [Term] id: CHEBI:26078 name: phosphoric acid namespace: chebi_ontology def: "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." [] subset: 3_STAR synonym: "[PO(OH)3]" RELATED [IUPAC] synonym: "acide phosphorique" RELATED [ChEBI] synonym: "acidum phosphoricum" RELATED [ChEBI] synonym: "H3PO4" RELATED [IUPAC] synonym: "Orthophosphoric acid" RELATED [KEGG_COMPOUND] synonym: "orthophosphoric acid" RELATED [NIST_Chemistry_WebBook] synonym: "Phosphate" RELATED [KEGG_COMPOUND] synonym: "Phosphoric acid" EXACT [KEGG_COMPOUND] synonym: "phosphoric acid" EXACT [IUPAC] synonym: "Phosphorsaeure" RELATED [ChEBI] synonym: "Phosphorsaeureloesungen" RELATED [ChEBI] synonym: "tetraoxophosphoric acid" EXACT IUPAC_NAME [IUPAC] synonym: "trihydrogen tetraoxophosphate(3-)" EXACT IUPAC_NAME [IUPAC] synonym: "trihydroxidooxidophosphorus" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:1921286 {source="Beilstein"} xref: CAS:7664-38-2 {source="NIST Chemistry WebBook"} xref: CAS:7664-38-2 {source="KEGG COMPOUND"} xref: CAS:7664-38-2 {source="ChemIDplus"} xref: Drug_Central:4478 {source="DrugCentral"} xref: Gmelin:2000 {source="Gmelin"} xref: HMDB:HMDB0002142 xref: KEGG:C00009 xref: KEGG:D05467 xref: KNApSAcK:C00007408 xref: PMID:11455380 {source="Europe PMC"} xref: PMID:15630224 {source="Europe PMC"} xref: PMID:17439666 {source="Europe PMC"} xref: PMID:17518491 {source="Europe PMC"} xref: PMID:22282755 {source="Europe PMC"} xref: PMID:22333268 {source="Europe PMC"} xref: PMID:22381614 {source="Europe PMC"} xref: PMID:22401268 {source="Europe PMC"} xref: Reaxys:1921286 {source="Reaxys"} xref: Wikipedia:Phosphoric_Acid is_a: CHEBI:59698 ! phosphoric acids relationship: has_role CHEBI:33287 ! fertilizer relationship: has_role CHEBI:46787 ! solvent relationship: has_role CHEBI:77746 ! human metabolite relationship: has_role CHEBI:84735 ! algal metabolite relationship: is_conjugate_acid_of CHEBI:39745 ! dihydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "97.99520" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.97690" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP(=O)(O[H])O[H]" xsd:string [Term] id: CHEBI:26079 name: phosphoric acid derivative namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:36359 ! phosphorus oxoacid derivative relationship: has_functional_parent CHEBI:26078 ! phosphoric acid [Term] id: CHEBI:26082 name: phosphorus molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "phosphorus molecular entities" RELATED [ChEBI] is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_part CHEBI:28659 ! phosphorus atom [Term] id: CHEBI:26708 name: sodium atom namespace: chebi_ontology subset: 3_STAR synonym: "11Na" RELATED [IUPAC] synonym: "Na" RELATED [IUPAC] synonym: "Natrium" RELATED [ChemIDplus] synonym: "natrium" RELATED [IUPAC] synonym: "sodio" RELATED [ChemIDplus] synonym: "sodium" EXACT IUPAC_NAME [IUPAC] synonym: "sodium" RELATED [ChEBI] xref: CAS:7440-23-5 {source="ChemIDplus"} xref: Gmelin:16221 {source="Gmelin"} xref: KEGG:C01330 xref: WebElements:Na is_a: CHEBI:22314 ! alkali metal atom relationship: has_role CHEBI:33937 ! macronutrient relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KEAYESYHFKHZAL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na]" xsd:string [Term] id: CHEBI:26712 name: sodium molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "sodium compounds" RELATED [ChEBI] synonym: "sodium molecular entities" RELATED [ChEBI] is_a: CHEBI:33296 ! alkali metal molecular entity relationship: has_part CHEBI:26708 ! sodium atom [Term] id: CHEBI:26714 name: sodium salt namespace: chebi_ontology def: "Any alkali metal salt having sodium(1+) as the cation." [] subset: 3_STAR synonym: "Natriumsalz" RELATED [ChEBI] synonym: "Natriumsalze" RELATED [ChEBI] synonym: "sodium salts" RELATED [ChEBI] is_a: CHEBI:26712 ! sodium molecular entity is_a: CHEBI:35479 ! alkali metal salt relationship: has_part CHEBI:29101 ! sodium(1+) [Term] id: CHEBI:26764 name: steroid hormone namespace: chebi_ontology def: "Any steroid that acts as hormone." [] subset: 3_STAR synonym: "hormona esteroide" RELATED [ChEBI] synonym: "hormonas esteroideas" RELATED [ChEBI] synonym: "hormone steroide" RELATED [ChEBI] synonym: "hormones steroides" RELATED [ChEBI] synonym: "steroid hormones" RELATED [ChEBI] synonym: "Steroidhormon" RELATED [ChEBI] synonym: "Steroidhormone" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid relationship: has_role CHEBI:24621 ! hormone [Term] id: CHEBI:26819 name: sulfuric ester namespace: chebi_ontology def: "An ester of an alcohol and sulfuric acid." [] subset: 3_STAR synonym: "sulfate ester" RELATED [ChEBI] synonym: "sulfuric acid ester" RELATED [ChEBI] synonym: "sulfuric acid esters" RELATED [ChEBI] is_a: CHEBI:35701 ! ester is_a: CHEBI:37826 ! sulfuric acid derivative property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]OS(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:26820 name: sulfates namespace: chebi_ontology def: "Salts and esters of sulfuric acid" [] subset: 3_STAR synonym: "sulfates" EXACT [ChEBI] synonym: "sulfuric acid derivative" RELATED [ChEBI] synonym: "sulphates" RELATED [ChEBI] is_a: CHEBI:37826 ! sulfuric acid derivative [Term] id: CHEBI:26833 name: sulfur atom namespace: chebi_ontology subset: 3_STAR synonym: "16S" RELATED [IUPAC] synonym: "azufre" RELATED [ChEBI] synonym: "Elemental sulfur" RELATED [KEGG_COMPOUND] synonym: "S" RELATED [KEGG_COMPOUND] synonym: "S" RELATED [IUPAC] synonym: "Schwefel" RELATED [ChEBI] synonym: "soufre" RELATED [ChEBI] synonym: "sulfur" EXACT IUPAC_NAME [IUPAC] synonym: "sulfur" RELATED [ChEBI] synonym: "sulfur" RELATED [UniProt] synonym: "sulphur" RELATED [ChEBI] synonym: "theion" RELATED [IUPAC] xref: CAS:7704-34-9 {source="ChemIDplus"} xref: CAS:7704-34-9 {source="NIST Chemistry WebBook"} xref: KEGG:C00087 xref: KEGG:D06527 xref: PPDB:605 xref: WebElements:S is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33303 ! chalcogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NINIDFKCEFEMDL-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "32.06600" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.97207" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[S]" xsd:string [Term] id: CHEBI:26835 name: sulfur molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "sulfur molecular entities" RELATED [ChEBI] synonym: "sulfur molecular entity" EXACT [ChEBI] is_a: CHEBI:33304 ! chalcogen molecular entity relationship: has_part CHEBI:26833 ! sulfur atom [Term] id: CHEBI:26836 name: sulfuric acid namespace: chebi_ontology def: "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." [] subset: 3_STAR synonym: "[S(OH)2O2]" RELATED [MolBase] synonym: "[SO2(OH)2]" RELATED [IUPAC] synonym: "Acide sulfurique" RELATED [ChemIDplus] synonym: "Acido sulfurico" RELATED [ChemIDplus] synonym: "Acidum sulfuricum" RELATED [ChemIDplus] synonym: "dihydrogen tetraoxosulfate" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidodioxidosulfur" EXACT IUPAC_NAME [IUPAC] synonym: "H2SO4" RELATED [IUPAC] synonym: "hydrogen tetraoxosulfate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen tetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "Schwefelsaeureloesungen" RELATED [ChemIDplus] synonym: "Sulfuric acid" EXACT [KEGG_COMPOUND] synonym: "sulfuric acid" EXACT IUPAC_NAME [IUPAC] synonym: "sulfuric acid" EXACT [ChEBI] synonym: "sulphuric acid" RELATED [MolBase] synonym: "tetraoxosulfuric acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:7664-93-9 {source="ChemIDplus"} xref: CAS:7664-93-9 {source="KEGG COMPOUND"} xref: CAS:7664-93-9 {source="NIST Chemistry WebBook"} xref: Gmelin:2122 {source="Gmelin"} xref: KEGG:C00059 xref: KEGG:D05963 xref: KNApSAcK:C00007530 xref: MolBase:4 xref: PMID:13568755 {source="Europe PMC"} xref: PMID:16122922 {source="Europe PMC"} xref: PMID:19397353 {source="Europe PMC"} xref: PMID:22047659 {source="Europe PMC"} xref: PMID:22136045 {source="Europe PMC"} xref: PMID:22204399 {source="Europe PMC"} xref: PMID:22267186 {source="Europe PMC"} xref: PMID:22296037 {source="Europe PMC"} xref: PMID:22364556 {source="Europe PMC"} xref: PMID:22435616 {source="Europe PMC"} xref: PPDB:606 xref: Reaxys:2037554 {source="Reaxys"} xref: Wikipedia:Sulfuric_acid is_a: CHEBI:33402 ! sulfur oxoacid relationship: has_role CHEBI:35223 ! catalyst relationship: is_conjugate_acid_of CHEBI:45696 ! hydrogensulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "98.07948" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "97.96738" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS(=O)(=O)O[H]" xsd:string [Term] id: CHEBI:26932 name: tetrapyrrole namespace: chebi_ontology def: "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [] subset: 3_STAR synonym: "a tetrapyrrole" RELATED [UniProt] synonym: "tetrapyrrole" EXACT IUPAC_NAME [IUPAC] synonym: "tetrapyrroles" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:38077 ! polypyrrole [Term] id: CHEBI:27027 name: micronutrient namespace: chebi_ontology def: "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." [] subset: 3_STAR synonym: "micronutrients" RELATED [ChEBI] synonym: "trace elements" RELATED [ChEBI] xref: Wikipedia:Micronutrient is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:27162 name: tryptamines namespace: chebi_ontology def: "Tryptamine and its substitution derivatives." [] subset: 3_STAR is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:27171 name: organic heterobicyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "heterobicyclic compounds" RELATED [ChEBI] synonym: "organic heterobicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33672 ! heterobicyclic compound is_a: CHEBI:38166 ! organic heteropolycyclic compound [Term] id: CHEBI:27207 name: univalent carboacyl group namespace: chebi_ontology def: "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "univalent acyl group" RELATED [ChEBI] synonym: "univalent carboacyl groups" RELATED [ChEBI] synonym: "univalent carboxylic acyl groups" RELATED [ChEBI] is_a: CHEBI:37838 ! carboacyl group [Term] id: CHEBI:27369 name: zwitterion namespace: chebi_ontology def: "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." [] subset: 3_STAR synonym: "compose zwitterionique" RELATED [IUPAC] synonym: "compuestos zwitterionicos" RELATED [IUPAC] synonym: "zwitterion" EXACT IUPAC_NAME [IUPAC] synonym: "zwitteriones" RELATED [IUPAC] synonym: "zwitterionic compounds" RELATED [IUPAC] synonym: "zwitterions" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51151 ! dipolar compound [Term] id: CHEBI:27594 name: carbon atom namespace: chebi_ontology alt_id: CHEBI:23009 alt_id: CHEBI:3399 subset: 3_STAR synonym: "6C" RELATED [IUPAC] synonym: "C" RELATED [KEGG_COMPOUND] synonym: "C" RELATED [IUPAC] synonym: "Carbon" RELATED [KEGG_COMPOUND] synonym: "carbon" EXACT IUPAC_NAME [IUPAC] synonym: "carbon" RELATED [ChEBI] synonym: "carbone" RELATED [ChEBI] synonym: "carbonium" RELATED [ChEBI] synonym: "carbono" RELATED [ChEBI] synonym: "Kohlenstoff" RELATED [ChEBI] xref: CAS:7440-44-0 {source="ChemIDplus"} xref: CAS:7440-44-0 {source="KEGG COMPOUND"} xref: KEGG:C06265 xref: WebElements:C is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33306 ! carbon group element atom relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OKTJSMMVPCPJKN-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "12.01070" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "12.00000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[C]" xsd:string [Term] id: CHEBI:28087 name: glycogen namespace: chebi_ontology alt_id: CHEBI:24379 alt_id: CHEBI:5466 def: "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." [] subset: 3_STAR synonym: "animal starch" RELATED [ChemIDplus] synonym: "Glycogen" EXACT [KEGG_COMPOUND] synonym: "liver starch" RELATED [ChemIDplus] synonym: "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1" RELATED [GlyTouCan] xref: CAS:9005-79-2 {source="KEGG COMPOUND"} xref: CAS:9005-79-2 {source="ChemIDplus"} xref: GlyGen:G99991IU xref: GlyTouCan:G99991IU xref: HMDB:HMDB0000757 xref: KEGG:C00182 xref: MetaCyc:CPD0-971 xref: Wikipedia:Glycogen is_a: CHEBI:24384 ! glycogens relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite [Term] id: CHEBI:28616 name: carbamic acid namespace: chebi_ontology alt_id: CHEBI:22504 alt_id: CHEBI:23002 alt_id: CHEBI:3386 alt_id: CHEBI:44573 def: "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." [] subset: 3_STAR synonym: "Aminoameisensaeure" RELATED [ChEBI] synonym: "Aminoformic acid" RELATED [KEGG_COMPOUND] synonym: "Carbamate" RELATED [KEGG_COMPOUND] synonym: "CARBAMIC ACID" EXACT [PDBeChem] synonym: "Carbamic acid" EXACT [KEGG_COMPOUND] synonym: "carbamic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Carbamidsaeure" RELATED [ChEBI] xref: Beilstein:1734754 {source="Beilstein"} xref: CAS:463-77-4 {source="KEGG COMPOUND"} xref: CAS:463-77-4 {source="ChemIDplus"} xref: DrugBank:DB04261 xref: Gmelin:130345 {source="Gmelin"} xref: KEGG:C01563 xref: PDBeChem:OUT xref: Wikipedia:Carbamic_acid is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:64708 ! one-carbon compound relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: is_conjugate_acid_of CHEBI:13941 ! carbamate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH3NO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "61.04006" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "61.01638" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC(O)=O" xsd:string [Term] id: CHEBI:28659 name: phosphorus atom namespace: chebi_ontology alt_id: CHEBI:26080 alt_id: CHEBI:8168 subset: 3_STAR synonym: "15P" RELATED [IUPAC] synonym: "fosforo" RELATED [ChEBI] synonym: "P" RELATED [IUPAC] synonym: "P" RELATED [KEGG_COMPOUND] synonym: "Phosphor" RELATED [ChEBI] synonym: "phosphore" RELATED [ChEBI] synonym: "Phosphorus" RELATED [KEGG_COMPOUND] synonym: "phosphorus" EXACT IUPAC_NAME [IUPAC] synonym: "phosphorus" RELATED [ChEBI] xref: CAS:7723-14-0 {source="ChemIDplus"} xref: CAS:7723-14-0 {source="KEGG COMPOUND"} xref: Gmelin:16235 {source="Gmelin"} xref: KEGG:C06262 xref: WebElements:P is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33300 ! pnictogen relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "OAICVXFJPJFONN-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "30.97376" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "30.97376" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[P]" xsd:string [Term] id: CHEBI:28790 name: serotonin namespace: chebi_ontology alt_id: CHEBI:1420 alt_id: CHEBI:26652 alt_id: CHEBI:49894 def: "A primary amino compound that is the 5-hydroxy derivative of tryptamine." [] subset: 3_STAR synonym: "3-(2-Aminoethyl)-1H-indol-5-ol" RELATED [KEGG_COMPOUND] synonym: "3-(2-aminoethyl)-1H-indol-5-ol" EXACT IUPAC_NAME [IUPAC] synonym: "5-HT" RELATED [IUPHAR] synonym: "5-Hydroxytryptamine" RELATED [KEGG_COMPOUND] synonym: "Enteramine" RELATED [KEGG_COMPOUND] synonym: "SEROTONIN" EXACT [PDBeChem] synonym: "Serotonin" EXACT [KEGG_COMPOUND] synonym: "serotonine" RELATED [ChEBI] synonym: "thrombocytin" RELATED [ChemIDplus] synonym: "thrombotonin" RELATED [ChemIDplus] xref: Beilstein:143524 {source="Beilstein"} xref: CAS:50-67-9 {source="KEGG COMPOUND"} xref: CAS:50-67-9 {source="ChemIDplus"} xref: Gmelin:1861995 {source="Gmelin"} xref: HMDB:HMDB0000259 xref: KEGG:C00780 xref: KNApSAcK:C00001429 xref: LINCS:LSM-6589 xref: MetaCyc:SEROTONIN xref: PDBeChem:SRO xref: PMID:18593914 {source="Europe PMC"} xref: PMID:22770225 {source="Europe PMC"} xref: PMID:24136337 {source="Europe PMC"} xref: Reaxys:143524 {source="Reaxys"} xref: Wikipedia:Serotonin is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:27162 ! tryptamines is_a: CHEBI:33853 ! phenols is_a: CHEBI:50994 ! primary amino compound is_a: CHEBI:84729 ! hydroxyindoles relationship: has_functional_parent CHEBI:16765 ! tryptamine relationship: has_role CHEBI:25512 ! neurotransmitter relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:350546 ! serotonin(1+) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H12N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "176.215" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "176.09496" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1=CC(=CC=2C(=CNC12)CCN)O" xsd:string [Term] id: CHEBI:28938 name: ammonium namespace: chebi_ontology alt_id: CHEBI:22534 alt_id: CHEBI:49783 alt_id: CHEBI:7435 def: "An onium cation obtained by protonation of ammonia." [] subset: 3_STAR synonym: "[NH4](+)" RELATED [MolBase] synonym: "ammonium" EXACT IUPAC_NAME [IUPAC] synonym: "ammonium" EXACT [ChEBI] synonym: "ammonium cation" RELATED [ChemIDplus] synonym: "ammonium ion" RELATED [PDBeChem] synonym: "Ammonium(1+)" RELATED [ChemIDplus] synonym: "azanium" EXACT IUPAC_NAME [IUPAC] synonym: "NH4(+)" RELATED [UniProt] synonym: "NH4(+)" RELATED [IUPAC] synonym: "NH4+" RELATED [KEGG_COMPOUND] xref: CAS:14798-03-9 {source="NIST Chemistry WebBook"} xref: CAS:14798-03-9 {source="ChemIDplus"} xref: Gmelin:84 {source="Gmelin"} xref: KEGG:C01342 xref: MetaCyc:AMMONIUM xref: MolBase:929 xref: PDBeChem:NH4 xref: PMID:11319011 {source="Europe PMC"} xref: PMID:11341317 {source="Europe PMC"} xref: PMID:12096804 {source="Europe PMC"} xref: PMID:14512268 {source="Europe PMC"} xref: PMID:14879753 {source="Europe PMC"} xref: PMID:16345391 {source="Europe PMC"} xref: PMID:16903292 {source="Europe PMC"} xref: PMID:17392693 {source="Europe PMC"} xref: PMID:18515490 {source="Europe PMC"} xref: PMID:19199063 {source="Europe PMC"} xref: PMID:19596600 {source="Europe PMC"} xref: PMID:19682559 {source="Europe PMC"} xref: PMID:19716251 {source="Europe PMC"} xref: PMID:21993530 {source="Europe PMC"} xref: PMID:22265469 {source="Europe PMC"} xref: PMID:22524020 {source="Europe PMC"} xref: PMID:22562341 {source="Europe PMC"} xref: PMID:22631217 {source="Europe PMC"} xref: Reaxys:16093784 {source="Reaxys"} xref: Wikipedia:Ammonium is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:50313 ! onium cation is_a: CHEBI:60242 ! monovalent inorganic cation relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:76971 ! Escherichia coli metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:16134 ! ammonia property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H4N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3N/h1H3/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "18.03850" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "18.03383" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N+]([H])([H])[H]" xsd:string [Term] id: CHEBI:28965 name: dicarboxylic acid dianion namespace: chebi_ontology alt_id: CHEBI:13632 alt_id: CHEBI:23688 alt_id: CHEBI:23689 alt_id: CHEBI:38711 def: "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." [] subset: 3_STAR synonym: "a dicarboxylate" RELATED [UniProt] synonym: "dicarboxylate" RELATED [ChEBI] synonym: "dicarboxylates" RELATED [ChEBI] synonym: "dicarboxylic acid dianion" EXACT [ChEBI] synonym: "dicarboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:35693 ! dicarboxylic acid anion is_a: CHEBI:38716 ! carboxylic acid dianion property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2O4R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "88.019" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "87.97966" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C(=O)[*]C([O-])=O" xsd:string [Term] id: CHEBI:28976 name: carbonic acid namespace: chebi_ontology alt_id: CHEBI:13351 alt_id: CHEBI:23017 alt_id: CHEBI:23744 alt_id: CHEBI:3401 subset: 3_STAR synonym: "[CO(OH)2]" RELATED [IUPAC] synonym: "Carbonic acid" EXACT [KEGG_COMPOUND] synonym: "carbonic acid" EXACT IUPAC_NAME [IUPAC] synonym: "Dihydrogen carbonate" RELATED [KEGG_COMPOUND] synonym: "dihydroxidooxidocarbon" EXACT IUPAC_NAME [IUPAC] synonym: "H2CO3" RELATED [KEGG_COMPOUND] synonym: "H2CO3" RELATED [IUPAC] synonym: "Koehlensaeure" RELATED [ChEBI] xref: CAS:463-79-6 {source="ChemIDplus"} xref: CAS:463-79-6 {source="KEGG COMPOUND"} xref: Gmelin:25554 {source="Gmelin"} xref: KEGG:C01353 xref: PDBeChem:CO3 is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36961 ! chalcocarbonic acid relationship: has_role CHEBI:75771 ! mouse metabolite relationship: is_conjugate_acid_of CHEBI:17544 ! hydrogencarbonate property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CH2O3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "62.02478" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "62.00039" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC(O)=O" xsd:string [Term] id: CHEBI:29067 name: carboxylic acid anion namespace: chebi_ontology alt_id: CHEBI:13626 alt_id: CHEBI:13945 alt_id: CHEBI:23026 alt_id: CHEBI:58657 def: "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a carboxylate" RELATED [UniProt] synonym: "carboxylic acid anions" RELATED [ChEBI] synonym: "carboxylic anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion relationship: is_conjugate_base_of CHEBI:33575 ! carboxylic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.00950" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:29101 name: sodium(1+) namespace: chebi_ontology alt_id: CHEBI:26717 alt_id: CHEBI:49766 alt_id: CHEBI:9175 def: "A monoatomic monocation obtained from sodium." [] subset: 3_STAR synonym: "Na(+)" RELATED [UniProt] synonym: "Na(+)" RELATED [IUPAC] synonym: "Na+" RELATED [KEGG_COMPOUND] synonym: "sodium cation" EXACT IUPAC_NAME [IUPAC] synonym: "SODIUM ION" RELATED [PDBeChem] synonym: "sodium(1+)" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(1+) ion" EXACT IUPAC_NAME [IUPAC] synonym: "sodium(I) cation" EXACT IUPAC_NAME [IUPAC] xref: CAS:17341-25-2 {source="ChemIDplus"} xref: CAS:17341-25-2 {source="NIST Chemistry WebBook"} xref: Gmelin:15196 {source="Gmelin"} xref: KEGG:C01330 xref: PDBeChem:NA is_a: CHEBI:25414 ! monoatomic monocation is_a: CHEBI:33504 ! alkali metal cation is_a: CHEBI:37246 ! elemental sodium is_a: CHEBI:60242 ! monovalent inorganic cation relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:77746 ! human metabolite property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Na" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/Na/q+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "FKNQFGJONOIPTF-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "22.98977" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "22.98922" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[Na+]" xsd:string [Term] id: CHEBI:29337 name: azanide namespace: chebi_ontology subset: 3_STAR synonym: "amide" EXACT IUPAC_NAME [IUPAC] synonym: "azanide" EXACT IUPAC_NAME [IUPAC] synonym: "dihydridonitrate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "NH2(-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:29340 ! hydridonitrate(2-) relationship: is_conjugate_base_of CHEBI:16134 ! ammonia property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2N/h1H2/q-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "HYGWNUKOUCZBND-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "16.02262" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "16.01927" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][N-][H]" xsd:string [Term] id: CHEBI:29340 name: hydridonitrate(2-) namespace: chebi_ontology def: "A divalent inorganic anion resulting from the removal of two protons from ammonia." [] subset: 3_STAR synonym: "azanediide" EXACT IUPAC_NAME [IUPAC] synonym: "hydridonitrate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "imide" RELATED [IUPAC] synonym: "NH(2-)" RELATED [IUPAC] is_a: CHEBI:35106 ! nitrogen hydride is_a: CHEBI:79388 ! divalent inorganic anion relationship: is_conjugate_base_of CHEBI:29337 ! azanide property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HN" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/HN/h1H/q-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "DZQYTNGKSBCIOE-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.01468" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.01200" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[N--][H]" xsd:string [Term] id: CHEBI:29793 name: hydridodioxygen(1+) namespace: chebi_ontology subset: 3_STAR synonym: "[HO2](+)" RELATED [ChEBI] synonym: "dioxidenium" EXACT IUPAC_NAME [IUPAC] synonym: "HO2(+)" RELATED [IUPAC] synonym: "HOO(+)" RELATED [ChEBI] synonym: "hydridodioxygen(1+)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:508 {source="Gmelin"} is_a: CHEBI:33693 ! oxygen hydride relationship: is_conjugate_acid_of CHEBI:15379 ! dioxygen property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/O2/c1-2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "33.00674" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "32.99711" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][O+]=O" xsd:string [Term] id: CHEBI:30089 name: acetate namespace: chebi_ontology alt_id: CHEBI:13704 alt_id: CHEBI:22165 alt_id: CHEBI:40480 def: "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." [] subset: 3_STAR synonym: "acetate" EXACT [UniProt] synonym: "acetate" EXACT IUPAC_NAME [IUPAC] synonym: "ACETATE ION" RELATED [PDBeChem] synonym: "acetic acid, ion(1-)" RELATED [ChemIDplus] synonym: "Azetat" RELATED [ChEBI] synonym: "CH3-COO(-)" RELATED [IUPAC] synonym: "Ethanoat" RELATED [ChEBI] synonym: "ethanoate" RELATED [ChEBI] synonym: "MeCO2 anion" RELATED [NIST_Chemistry_WebBook] xref: Beilstein:1901470 {source="Beilstein"} xref: CAS:71-50-1 {source="ChemIDplus"} xref: CAS:71-50-1 {source="NIST Chemistry WebBook"} xref: DrugBank:DB03166 xref: Gmelin:1379 {source="Gmelin"} xref: KEGG:C00033 xref: MetaCyc:ACET xref: PDBeChem:ACT xref: PMID:17190852 {source="Europe PMC"} xref: PMID:22211106 {source="Europe PMC"} xref: PMID:22371380 {source="Europe PMC"} xref: Reaxys:1901470 {source="Reaxys"} xref: UM-BBD_compID:c0050 {source="UM-BBD"} xref: Wikipedia:Acetate is_a: CHEBI:35757 ! monocarboxylic acid anion relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:15366 ! acetic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04402" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01385" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC([O-])=O" xsd:string [Term] id: CHEBI:30212 name: photon namespace: chebi_ontology alt_id: CHEBI:10581 alt_id: CHEBI:14383 def: "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." [] subset: 3_STAR synonym: "foton" RELATED [ChEBI] synonym: "gamma" RELATED [IUPAC] synonym: "hnu" RELATED [IUPAC] synonym: "hnu" RELATED [UniProt] synonym: "Lichtquant" RELATED [ChEBI] synonym: "Light" RELATED [KEGG_COMPOUND] synonym: "light quantum" RELATED [ChEBI] synonym: "photon" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00205 is_a: CHEBI:36341 ! boson property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "0.0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "0.0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*" xsd:string [Term] id: CHEBI:3098 name: bile acid namespace: chebi_ontology def: "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." [] subset: 3_STAR synonym: "5beta-bile acid" RELATED [ChEBI] synonym: "5beta-bile acids" RELATED [ChEBI] synonym: "Bile acid" EXACT [KEGG_COMPOUND] synonym: "bile acids" RELATED [ChEBI] synonym: "Bile salt" RELATED [KEGG_COMPOUND] synonym: "Gallensaeure" RELATED [ChEBI] synonym: "Gallensaeuren" RELATED [ChEBI] xref: KEGG:C01558 is_a: CHEBI:138366 ! bile acids is_a: CHEBI:24663 ! hydroxy-5beta-cholanic acid [Term] id: CHEBI:32952 name: amine namespace: chebi_ontology alt_id: CHEBI:13814 alt_id: CHEBI:22474 alt_id: CHEBI:2641 def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [] subset: 3_STAR synonym: "Amin" RELATED [ChEBI] synonym: "Amine" EXACT [KEGG_COMPOUND] synonym: "amines" EXACT IUPAC_NAME [IUPAC] synonym: "Substituted amine" RELATED [KEGG_COMPOUND] xref: KEGG:C00706 is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:32988 name: amide namespace: chebi_ontology alt_id: CHEBI:22473 alt_id: CHEBI:2633 def: "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "Amide" EXACT [KEGG_COMPOUND] synonym: "amides" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00241 is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:33232 name: application namespace: chebi_ontology def: "Intended use of the molecular entity or part thereof by humans." [] subset: 3_STAR is_a: BFO:0000023 ! role is_a: CHEBI:50906 ! role [Term] id: CHEBI:33233 name: fundamental particle namespace: chebi_ontology def: "A particle not known to have substructure." [] subset: 3_STAR synonym: "elementary particle" EXACT IUPAC_NAME [IUPAC] synonym: "elementary particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:33238 name: monoatomic entity namespace: chebi_ontology def: "A monoatomic entity is a molecular entity consisting of a single atom." [] subset: 3_STAR synonym: "atomic entity" RELATED [ChEBI] synonym: "monoatomic entities" RELATED [ChEBI] is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33241 name: oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:37577 ! heteroatomic molecular entity relationship: has_functional_parent CHEBI:24833 ! oxoacid [Term] id: CHEBI:33242 name: inorganic hydride namespace: chebi_ontology subset: 3_STAR synonym: "inorganic hydrides" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:33245 name: organic fundamental parent namespace: chebi_ontology def: "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." [] subset: 3_STAR synonym: "organic fundamental parents" RELATED [ChEBI] synonym: "organic parent hydrides" RELATED [ChEBI] is_a: CHEBI:37175 ! organic hydride is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33246 name: inorganic group namespace: chebi_ontology def: "Any substituent group which does not contain carbon." [] subset: 3_STAR synonym: "inorganic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group [Term] id: CHEBI:33247 name: organic group namespace: chebi_ontology def: "Any substituent group or skeleton containing carbon." [] subset: 3_STAR synonym: "organic groups" RELATED [ChEBI] is_a: CHEBI:24433 ! group relationship: is_substituent_group_from CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33249 name: organyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." [] subset: 3_STAR synonym: "groupe organyle" RELATED [IUPAC] synonym: "grupo organilo" RELATED [IUPAC] synonym: "grupos organilo" RELATED [IUPAC] synonym: "organyl group" EXACT IUPAC_NAME [IUPAC] synonym: "organyl groups" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:51447 ! organic univalent group [Term] id: CHEBI:33250 name: atom namespace: chebi_ontology alt_id: CHEBI:22671 alt_id: CHEBI:23907 def: "A chemical entity constituting the smallest component of an element having the chemical properties of the element." [] subset: 3_STAR synonym: "atom" EXACT IUPAC_NAME [IUPAC] synonym: "atome" RELATED [IUPAC] synonym: "atomo" RELATED [IUPAC] synonym: "atoms" RELATED [ChEBI] synonym: "atomus" RELATED [ChEBI] synonym: "element" RELATED [ChEBI] synonym: "elements" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity relationship: has_part CHEBI:10545 ! electron relationship: has_part CHEBI:33252 ! atomic nucleus [Term] id: CHEBI:33252 name: atomic nucleus namespace: chebi_ontology def: "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." [] subset: 3_STAR synonym: "Atomkern" RELATED [ChEBI] synonym: "Kern" RELATED [ChEBI] synonym: "noyau" RELATED [IUPAC] synonym: "noyau atomique" RELATED [ChEBI] synonym: "nuclei" RELATED [ChEBI] synonym: "nucleo" RELATED [IUPAC] synonym: "nucleo atomico" RELATED [ChEBI] synonym: "nucleus" EXACT IUPAC_NAME [IUPAC] synonym: "nucleus atomi" RELATED [ChEBI] is_a: CHEBI:36347 ! nuclear particle relationship: has_part CHEBI:33253 ! nucleon [Term] id: CHEBI:33253 name: nucleon namespace: chebi_ontology def: "Heavy nuclear particle: proton or neutron." [] subset: 3_STAR synonym: "nucleon" EXACT [IUPAC] synonym: "nucleon" EXACT IUPAC_NAME [IUPAC] synonym: "nucleons" RELATED [ChEBI] synonym: "Nukleon" RELATED [ChEBI] synonym: "Nukleonen" RELATED [ChEBI] is_a: CHEBI:36339 ! baryon is_a: CHEBI:36347 ! nuclear particle [Term] id: CHEBI:33256 name: primary amide namespace: chebi_ontology def: "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [] subset: 3_STAR synonym: "primary amide" EXACT [IUPAC] synonym: "primary amides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:32988 ! amide [Term] id: CHEBI:33259 name: elemental molecular entity namespace: chebi_ontology def: "A molecular entity all atoms of which have the same atomic number." [] subset: 3_STAR synonym: "homoatomic entity" RELATED [ChEBI] synonym: "homoatomic molecular entities" RELATED [ChEBI] synonym: "homoatomic molecular entity" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity [Term] id: CHEBI:33262 name: elemental oxygen namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:33259 ! elemental molecular entity [Term] id: CHEBI:33263 name: diatomic oxygen namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:33262 ! elemental oxygen property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "31.999" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "31.98983" xsd:string [Term] id: CHEBI:33273 name: polyatomic anion namespace: chebi_ontology def: "An anion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic anions" RELATED [ChEBI] is_a: CHEBI:22563 ! anion is_a: CHEBI:36358 ! polyatomic ion [Term] id: CHEBI:33280 name: molecular messenger namespace: chebi_ontology subset: 3_STAR synonym: "chemical messenger" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33281 name: antimicrobial agent namespace: chebi_ontology alt_id: CHEBI:22582 def: "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." [] subset: 3_STAR synonym: "antibiotic" RELATED [ChEBI] synonym: "antibiotics" RELATED [ChEBI] synonym: "Antibiotika" RELATED [ChEBI] synonym: "Antibiotikum" RELATED [ChEBI] synonym: "antibiotique" RELATED [IUPAC] synonym: "antimicrobial" RELATED [ChEBI] synonym: "antimicrobial agents" RELATED [ChEBI] synonym: "antimicrobials" RELATED [ChEBI] synonym: "microbicide" RELATED [ChEBI] synonym: "microbicides" RELATED [ChEBI] xref: PMID:12964249 {source="Europe PMC"} xref: PMID:22117953 {source="Europe PMC"} xref: PMID:22439833 {source="Europe PMC"} xref: PMID:22849268 {source="Europe PMC"} xref: PMID:22849276 {source="Europe PMC"} xref: PMID:22958833 {source="Europe PMC"} is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:33284 name: nutrient namespace: chebi_ontology def: "A nutrient is a food component that an organism uses to survive and grow." [] subset: 3_STAR synonym: "nutrients" RELATED [ChEBI] is_a: CHEBI:78295 ! food component [Term] id: CHEBI:33285 name: heteroorganic entity namespace: chebi_ontology def: "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." [] subset: 3_STAR synonym: "heteroorganic entities" RELATED [ChEBI] synonym: "organoelement compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33286 name: agrochemical namespace: chebi_ontology def: "An agrochemical is a substance that is used in agriculture or horticulture." [] subset: 3_STAR synonym: "agrichemical" RELATED [ChEBI] synonym: "agrichemicals" RELATED [ChEBI] synonym: "agricultural chemicals" RELATED [ChEBI] synonym: "agrochemicals" RELATED [ChEBI] xref: Wikipedia:Agrochemical is_a: CHEBI:33232 ! application [Term] id: CHEBI:33287 name: fertilizer namespace: chebi_ontology def: "A fertilizer is any substance that is added to soil or water to assist the growth of plants." [] subset: 3_STAR synonym: "fertiliser" RELATED [ChEBI] synonym: "fertilizers" RELATED [ChEBI] is_a: CHEBI:33286 ! agrochemical [Term] id: CHEBI:33296 name: alkali metal molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms of an alkali metal." [] subset: 3_STAR synonym: "alkali metal molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:22314 ! alkali metal atom [Term] id: CHEBI:33300 name: pnictogen namespace: chebi_ontology def: "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." [] subset: 3_STAR synonym: "group 15 elements" RELATED [ChEBI] synonym: "group V elements" RELATED [ChEBI] synonym: "nitrogenoideos" RELATED [ChEBI] synonym: "nitrogenoides" RELATED [ChEBI] synonym: "pnictogene" RELATED [ChEBI] synonym: "pnictogenes" RELATED [ChEBI] synonym: "pnictogens" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33302 name: pnictogen molecular entity namespace: chebi_ontology def: "A p-block molecular entity containing any pnictogen." [] subset: 3_STAR synonym: "pnictogen molecular entities" RELATED [ChEBI] synonym: "pnictogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33300 ! pnictogen [Term] id: CHEBI:33303 name: chalcogen namespace: chebi_ontology def: "Any p-block element belonging to the group 16 family of the periodic table." [] subset: 3_STAR synonym: "anfigeno" RELATED [ChEBI] synonym: "anfigenos" RELATED [ChEBI] synonym: "calcogeno" RELATED [ChEBI] synonym: "calcogenos" RELATED [ChEBI] synonym: "chalcogen" EXACT IUPAC_NAME [IUPAC] synonym: "chalcogene" RELATED [ChEBI] synonym: "chalcogenes" RELATED [ChEBI] synonym: "chalcogens" EXACT IUPAC_NAME [IUPAC] synonym: "Chalkogen" RELATED [ChEBI] synonym: "Chalkogene" RELATED [ChEBI] synonym: "group 16 elements" RELATED [ChEBI] synonym: "group VI elements" RELATED [ChEBI] xref: PMID:17084588 {source="Europe PMC"} is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33304 name: chalcogen molecular entity namespace: chebi_ontology def: "Any p-block molecular entity containing a chalcogen." [] subset: 3_STAR synonym: "chalcogen compounds" RELATED [ChEBI] synonym: "chalcogen molecular entities" RELATED [ChEBI] synonym: "chalcogen molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33303 ! chalcogen [Term] id: CHEBI:33306 name: carbon group element atom namespace: chebi_ontology subset: 3_STAR synonym: "carbon group element" RELATED [ChEBI] synonym: "carbon group elements" RELATED [ChEBI] synonym: "carbonoides" RELATED [ChEBI] synonym: "cristallogene" RELATED [ChEBI] synonym: "cristallogenes" RELATED [ChEBI] synonym: "group 14 elements" EXACT IUPAC_NAME [IUPAC] synonym: "group IV elements" RELATED [ChEBI] is_a: CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33308 name: carboxylic ester namespace: chebi_ontology alt_id: CHEBI:13204 alt_id: CHEBI:23028 alt_id: CHEBI:3408 def: "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." [] subset: 3_STAR synonym: "a carboxylic ester" RELATED [UniProt] synonym: "carboxylic acid esters" RELATED [ChEBI] synonym: "Carboxylic ester" EXACT [KEGG_COMPOUND] synonym: "carboxylic esters" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C02391 xref: Wikipedia:Ester is_a: CHEBI:35701 ! ester is_a: CHEBI:36586 ! carbonyl compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)O[*]" xsd:string [Term] id: CHEBI:33318 name: main group element atom namespace: chebi_ontology def: "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." [] subset: 3_STAR synonym: "Hauptgruppenelement" RELATED [ChEBI] synonym: "Hauptgruppenelemente" RELATED [ChEBI] synonym: "main group element" RELATED [ChEBI] synonym: "main group elements" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33402 name: sulfur oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "oxoacids of sulfur" RELATED [ChEBI] synonym: "sulfur oxoacids" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33484 ! chalcogen oxoacid [Term] id: CHEBI:33408 name: pnictogen oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen oxoacids" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_role CHEBI:138103 ! inorganic acid [Term] id: CHEBI:33424 name: sulfur oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "sulfur oxoacid derivative" EXACT [ChEBI] synonym: "sulfur oxoacid derivatives" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33241 ! oxoacid derivative [Term] id: CHEBI:33457 name: phosphorus oxoacid namespace: chebi_ontology def: "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." [] subset: 3_STAR synonym: "oxoacids of phosphorus" RELATED [ChEBI] synonym: "Oxosaeure des Phosphors" RELATED [ChEBI] synonym: "phosphorus oxoacid" EXACT [ChEBI] synonym: "phosphorus oxoacids" RELATED [ChEBI] is_a: CHEBI:33408 ! pnictogen oxoacid is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives [Term] id: CHEBI:33459 name: pnictogen oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen oxoanion" EXACT [ChEBI] synonym: "pnictogen oxoanions" RELATED [ChEBI] is_a: CHEBI:33302 ! pnictogen molecular entity is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33461 name: phosphorus oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "oxoanions of phosphorus" RELATED [ChEBI] synonym: "phosphorus oxoanion" EXACT [ChEBI] synonym: "phosphorus oxoanions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion is_a: CHEBI:26082 ! phosphorus molecular entity is_a: CHEBI:33459 ! pnictogen oxoanion [Term] id: CHEBI:33482 name: sulfur oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "oxoanions of sulfur" RELATED [ChEBI] synonym: "sulfur oxoanion" EXACT [ChEBI] synonym: "sulfur oxoanions" RELATED [ChEBI] is_a: CHEBI:26835 ! sulfur molecular entity is_a: CHEBI:33485 ! chalcogen oxoanion [Term] id: CHEBI:33484 name: chalcogen oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen oxoacid" EXACT [ChEBI] synonym: "chalcogen oxoacids" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid relationship: has_role CHEBI:138103 ! inorganic acid [Term] id: CHEBI:33485 name: chalcogen oxoanion namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen oxoanion" EXACT [ChEBI] synonym: "chalcogen oxoanions" RELATED [ChEBI] is_a: CHEBI:35406 ! oxoanion [Term] id: CHEBI:33504 name: alkali metal cation namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal cations" RELATED [ChEBI] is_a: CHEBI:25213 ! metal cation [Term] id: CHEBI:33521 name: metal atom namespace: chebi_ontology alt_id: CHEBI:25217 alt_id: CHEBI:6788 def: "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." [] subset: 3_STAR synonym: "elemental metal" RELATED [ChEBI] synonym: "elemental metals" RELATED [ChEBI] synonym: "metal element" RELATED [ChEBI] synonym: "metal elements" RELATED [ChEBI] synonym: "metals" RELATED [ChEBI] xref: KEGG:C00050 xref: PMID:21784043 {source="Europe PMC"} xref: Wikipedia:Metal is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33558 name: alpha-amino-acid anion namespace: chebi_ontology def: "An amino-acid anion obtained by deprotonation of any alpha-amino acid." [] subset: 3_STAR synonym: "alpha-amino acid anions" RELATED [ChEBI] synonym: "alpha-amino-acid anion" EXACT [ChEBI] synonym: "alpha-amino-acid anions" RELATED [ChEBI] is_a: CHEBI:37022 ! amino-acid anion relationship: is_conjugate_base_of CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33559 name: s-block element atom namespace: chebi_ontology subset: 3_STAR synonym: "s-block element" RELATED [ChEBI] synonym: "s-block elements" RELATED [ChEBI] is_a: CHEBI:33250 ! atom [Term] id: CHEBI:33560 name: p-block element atom namespace: chebi_ontology def: "Any main group element atom belonging to the p-block of the periodic table." [] subset: 3_STAR synonym: "p-block element" RELATED [ChEBI] synonym: "p-block elements" RELATED [ChEBI] is_a: CHEBI:33318 ! main group element atom [Term] id: CHEBI:33566 name: catechols namespace: chebi_ontology alt_id: CHEBI:134187 alt_id: CHEBI:13628 alt_id: CHEBI:18862 def: "Any compound containing an o-diphenol component." [] subset: 3_STAR synonym: "1,2-benzenediols" RELATED [ChEBI] synonym: "a catechol" RELATED [UniProt] synonym: "benzene-1,2-diols" RELATED [ChEBI] xref: KEGG:C15571 is_a: CHEBI:33570 ! benzenediols property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H2O2R4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "106.079" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "106.00548" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC1=C(O)C(*)=C(*)C(*)=C1*" xsd:string [Term] id: CHEBI:33567 name: catecholamine namespace: chebi_ontology alt_id: CHEBI:23056 alt_id: CHEBI:3468 def: "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [] subset: 3_STAR synonym: "Catecholamine" EXACT [KEGG_COMPOUND] synonym: "catecholamines" EXACT IUPAC_NAME [IUPAC] synonym: "catecholamines" RELATED [ChEBI] xref: KEGG:C02012 is_a: CHEBI:25375 ! monoamine molecular messenger is_a: CHEBI:33566 ! catechols property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H9NO2R2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "151.163" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "151.06333" xsd:string [Term] id: CHEBI:33569 name: noradrenaline namespace: chebi_ontology def: "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." [] subset: 3_STAR synonym: "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] synonym: "noradrenalina" RELATED [ChEBI] synonym: "norepinephrine" RELATED [ChEBI] xref: Beilstein:2210994 {source="Beilstein"} xref: CAS:138-65-8 {source="NIST Chemistry WebBook"} xref: CAS:138-65-8 {source="ChemIDplus"} xref: Gmelin:863925 {source="Gmelin"} xref: LINCS:LSM-5181 is_a: CHEBI:33567 ! catecholamine relationship: has_role CHEBI:76967 ! human xenobiotic metabolite relationship: is_conjugate_base_of CHEBI:166902 ! noradrenaline(1+) property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NCC(O)c1ccc(O)c(O)c1" xsd:string [Term] id: CHEBI:33570 name: benzenediols namespace: chebi_ontology alt_id: CHEBI:22705 alt_id: CHEBI:22711 subset: 3_STAR is_a: CHEBI:33853 ! phenols [Term] id: CHEBI:33571 name: (S)-noradrenaline namespace: chebi_ontology def: "The S-enantiomer of noradrenaline." [] subset: 3_STAR synonym: "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:2937999 {source="Beilstein"} xref: LINCS:LSM-37072 xref: Reaxys:2937999 {source="Reaxys"} is_a: CHEBI:33569 ! noradrenaline relationship: is_enantiomer_of CHEBI:18357 ! (R)-noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H11NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-MRVPVSSYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "169.17788" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "169.07389" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC[C@@H](O)c1ccc(O)c(O)c1" xsd:string [Term] id: CHEBI:33575 name: carboxylic acid namespace: chebi_ontology alt_id: CHEBI:13428 alt_id: CHEBI:13627 alt_id: CHEBI:23027 def: "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." [] subset: 3_STAR synonym: "acide carboxylique" RELATED [IUPAC] synonym: "acides carboxyliques" RELATED [IUPAC] synonym: "acido carboxilico" RELATED [IUPAC] synonym: "acidos carboxilicos" RELATED [IUPAC] synonym: "Carbonsaeure" RELATED [ChEBI] synonym: "Carbonsaeuren" RELATED [ChEBI] synonym: "carboxylic acid" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Karbonsaeure" RELATED [ChEBI] synonym: "RC(=O)OH" RELATED [IUPAC] xref: PMID:17147560 {source="Europe PMC"} xref: PMID:18433345 {source="Europe PMC"} xref: Wikipedia:Carboxylic_acid is_a: CHEBI:35605 ! carbon oxoacid is_a: CHEBI:36586 ! carbonyl compound is_a: CHEBI:64709 ! organic acid relationship: has_part CHEBI:46883 ! carboxy group relationship: is_conjugate_acid_of CHEBI:29067 ! carboxylic acid anion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01740" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OC([*])=O" xsd:string [Term] id: CHEBI:33579 name: main group molecular entity namespace: chebi_ontology def: "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." [] subset: 3_STAR synonym: "main group compounds" RELATED [ChEBI] synonym: "main group molecular entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:33318 ! main group element atom [Term] id: CHEBI:33582 name: carbon group molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "carbon group molecular entities" RELATED [ChEBI] synonym: "carbon group molecular entity" EXACT [ChEBI] is_a: CHEBI:33675 ! p-block molecular entity relationship: has_part CHEBI:33306 ! carbon group element atom [Term] id: CHEBI:33595 name: cyclic compound namespace: chebi_ontology def: "Any molecule that consists of a series of atoms joined together to form a ring." [] subset: 3_STAR synonym: "cyclic compounds" RELATED [ChEBI] xref: Wikipedia:Cyclic_compound is_a: CHEBI:25367 ! molecule [Term] id: CHEBI:33608 name: hydrogen molecular entity namespace: chebi_ontology subset: 3_STAR synonym: "hydrogen compounds" RELATED [ChEBI] synonym: "hydrogen molecular entities" RELATED [ChEBI] is_a: CHEBI:33674 ! s-block molecular entity relationship: has_part CHEBI:49637 ! hydrogen atom [Term] id: CHEBI:33635 name: polycyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33636 name: bicyclic compound namespace: chebi_ontology def: "A molecule that features two fused rings." [] subset: 3_STAR synonym: "bicyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33655 name: aromatic compound namespace: chebi_ontology def: "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." [] subset: 3_STAR synonym: "aromatic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "aromatic molecular entity" EXACT IUPAC_NAME [IUPAC] synonym: "aromatics" RELATED [ChEBI] synonym: "aromatische Verbindungen" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:33659 name: organic aromatic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic aromatic compounds" RELATED [ChEBI] is_a: CHEBI:33655 ! aromatic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:33671 name: heteropolycyclic compound namespace: chebi_ontology def: "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." [] subset: 3_STAR synonym: "heteropolycyclic compounds" EXACT IUPAC_NAME [IUPAC] synonym: "polyheterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33672 name: heterobicyclic compound namespace: chebi_ontology def: "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." [] subset: 3_STAR synonym: "heterobicyclic compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33636 ! bicyclic compound is_a: CHEBI:5686 ! heterocyclic compound [Term] id: CHEBI:33674 name: s-block molecular entity namespace: chebi_ontology def: "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." [] subset: 3_STAR synonym: "s-block compounds" RELATED [ChEBI] synonym: "s-block molecular entities" RELATED [ChEBI] synonym: "s-block molecular entity" EXACT [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33559 ! s-block element atom [Term] id: CHEBI:33675 name: p-block molecular entity namespace: chebi_ontology def: "A main group molecular entity that contains one or more atoms of a p-block element." [] subset: 3_STAR synonym: "p-block compounds" RELATED [ChEBI] synonym: "p-block molecular entities" RELATED [ChEBI] synonym: "p-block molecular entitiy" RELATED [ChEBI] is_a: CHEBI:33579 ! main group molecular entity relationship: has_part CHEBI:33560 ! p-block element atom [Term] id: CHEBI:33692 name: hydrides namespace: chebi_ontology def: "Hydrides are chemical compounds of hydrogen with other chemical elements." [] subset: 3_STAR is_a: CHEBI:33608 ! hydrogen molecular entity is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:33693 name: oxygen hydride namespace: chebi_ontology subset: 3_STAR synonym: "hydrides of oxygen" RELATED [ChEBI] synonym: "oxygen hydride" EXACT [ChEBI] synonym: "oxygen hydrides" RELATED [ChEBI] is_a: CHEBI:36902 ! chalcogen hydride [Term] id: CHEBI:33694 name: biomacromolecule namespace: chebi_ontology def: "A macromolecule formed by a living organism." [] subset: 3_STAR synonym: "biomacromolecules" RELATED [ChEBI] synonym: "biopolymer" EXACT IUPAC_NAME [IUPAC] synonym: "Biopolymere" RELATED [ChEBI] synonym: "biopolymers" RELATED [ChEBI] is_a: CHEBI:33839 ! macromolecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33695 name: information biomacromolecule namespace: chebi_ontology subset: 3_STAR synonym: "genetically encoded biomacromolecules" RELATED [ChEBI] synonym: "genetically encoded biopolymers" RELATED [ChEBI] synonym: "information biomacromolecules" RELATED [ChEBI] synonym: "information biopolymers" RELATED [ChEBI] synonym: "information macromolecule" RELATED [ChEBI] synonym: "information macromolecules" RELATED [ChEBI] is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:33696 name: nucleic acid namespace: chebi_ontology def: "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." [] subset: 3_STAR synonym: "acide nucleique" RELATED [ChEBI] synonym: "acides nucleiques" RELATED [ChEBI] synonym: "acido nucleico" RELATED [ChEBI] synonym: "acidos nucleicos" RELATED [ChEBI] synonym: "NA" RELATED [ChEBI] synonym: "nucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "Nukleinsaeure" RELATED [ChEBI] synonym: "Nukleinsaeuren" RELATED [ChEBI] is_a: CHEBI:15986 ! polynucleotide relationship: has_part CHEBI:33791 ! canonical nucleoside residue relationship: has_part CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:33697 name: ribonucleic acid namespace: chebi_ontology def: "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." [] subset: 3_STAR synonym: "pentosenucleic acids" RELATED [ChemIDplus] synonym: "ribonucleic acid" EXACT [IUPAC] synonym: "ribonucleic acids" EXACT IUPAC_NAME [IUPAC] synonym: "ribonucleic acids" RELATED [ChEBI] synonym: "Ribonukleinsaeure" RELATED [ChEBI] synonym: "ribose nucleic acid" RELATED [ChEBI] synonym: "RNA" RELATED [UniProt] synonym: "RNA" RELATED [IUPAC] synonym: "RNS" RELATED [ChEBI] synonym: "yeast nucleic acid" RELATED [ChEBI] xref: CAS:63231-63-0 {source="ChemIDplus"} is_a: CHEBI:33696 ! nucleic acid relationship: has_part CHEBI:33792 ! canonical ribonucleoside residue relationship: has_part CHEBI:50299 ! canonical ribonucleotide residue [Term] id: CHEBI:33700 name: proteinogenic amino-acid residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical amino-acid residue" RELATED [ChEBI] synonym: "canonical amino-acid residues" RELATED [ChEBI] synonym: "common amino acid residues" RELATED [ChEBI] synonym: "proteinogenic amino-acid residues" RELATED [ChEBI] synonym: "standard amino acid residues" RELATED [ChEBI] synonym: "standard amino-acid residues" RELATED [ChEBI] is_a: CHEBI:33710 ! alpha-amino-acid residue [Term] id: CHEBI:33702 name: polyatomic cation namespace: chebi_ontology def: "A cation consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic cations" RELATED [ChEBI] is_a: CHEBI:36358 ! polyatomic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:33704 name: alpha-amino acid namespace: chebi_ontology alt_id: CHEBI:10208 alt_id: CHEBI:13779 alt_id: CHEBI:22442 alt_id: CHEBI:2642 def: "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." [] subset: 3_STAR synonym: "alpha-amino acid" EXACT IUPAC_NAME [IUPAC] synonym: "alpha-amino acids" RELATED [JCBN] synonym: "alpha-amino acids" RELATED [ChEBI] synonym: "alpha-amino carboxylic acids" RELATED [IUPAC] synonym: "Amino acid" RELATED [KEGG_COMPOUND] synonym: "Amino acids" RELATED [KEGG_COMPOUND] xref: KEGG:C00045 xref: KEGG:C05167 is_a: CHEBI:33709 ! amino acid relationship: is_conjugate_acid_of CHEBI:33558 ! alpha-amino-acid anion relationship: is_tautomer_of CHEBI:78608 ! alpha-amino acid zwitterion property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.05870" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "NC([*])C(O)=O" xsd:string [Term] id: CHEBI:33708 name: amino-acid residue namespace: chebi_ontology def: "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." [] subset: 3_STAR synonym: "amino acid residue" RELATED [ChEBI] synonym: "amino-acid residue" EXACT IUPAC_NAME [IUPAC] synonym: "amino-acid residues" RELATED [JCBN] is_a: CHEBI:33247 ! organic group relationship: is_substituent_group_from CHEBI:33709 ! amino acid [Term] id: CHEBI:33709 name: amino acid namespace: chebi_ontology alt_id: CHEBI:13815 alt_id: CHEBI:22477 def: "A carboxylic acid containing one or more amino groups." [] subset: 3_STAR synonym: "amino acids" RELATED [ChEBI] synonym: "Aminocarbonsaeure" RELATED [ChEBI] synonym: "Aminokarbonsaeure" RELATED [ChEBI] synonym: "Aminosaeure" RELATED [ChEBI] xref: Wikipedia:Amino_acid is_a: CHEBI:33575 ! carboxylic acid is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_acid_of CHEBI:37022 ! amino-acid anion [Term] id: CHEBI:33710 name: alpha-amino-acid residue namespace: chebi_ontology subset: 3_STAR synonym: "alpha-amino-acid residues" RELATED [ChEBI] is_a: CHEBI:33708 ! amino-acid residue relationship: is_substituent_group_from CHEBI:33704 ! alpha-amino acid [Term] id: CHEBI:33720 name: carbohydrate acid namespace: chebi_ontology subset: 3_STAR synonym: "carbohydrate acid" EXACT [ChEBI] synonym: "carbohydrate acids" RELATED [ChEBI] is_a: CHEBI:16646 ! carbohydrate is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:33721 ! carbohydrate acid anion [Term] id: CHEBI:33721 name: carbohydrate acid anion namespace: chebi_ontology subset: 3_STAR synonym: "carbohydrate acid anion" EXACT [ChEBI] synonym: "carbohydrate acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:33720 ! carbohydrate acid [Term] id: CHEBI:33791 name: canonical nucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical nucleoside residues" RELATED [ChEBI] synonym: "common nucleoside residues" RELATED [CBN] synonym: "nucleoside residue" RELATED [CBN] synonym: "standard nucleoside residues" RELATED [ChEBI] is_a: CHEBI:50320 ! nucleoside residue [Term] id: CHEBI:33792 name: canonical ribonucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical ribonucleoside residues" RELATED [ChEBI] synonym: "common ribonucleoside residue" RELATED [CBN] synonym: "common ribonucleoside residues" RELATED [CBN] synonym: "N" RELATED [CBN] synonym: "Nuc" RELATED [CBN] synonym: "standard ribonucleoside residues" RELATED [ChEBI] is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33793 name: canonical deoxyribonucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical deoxyribonucleoside residues" RELATED [ChEBI] synonym: "common 2'-deoxyribonucleoside residue" RELATED [CBN] synonym: "common 2'-deoxyribonucleoside residues" RELATED [CBN] synonym: "dN" RELATED [CBN] synonym: "dNuc" RELATED [CBN] synonym: "standard deoxyribonucleoside residues" RELATED [ChEBI] is_a: CHEBI:33791 ! canonical nucleoside residue [Term] id: CHEBI:33822 name: organic hydroxy compound namespace: chebi_ontology alt_id: CHEBI:64710 def: "An organic compound having at least one hydroxy group attached to a carbon atom." [] subset: 3_STAR synonym: "hydroxy compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organic alcohol" RELATED [ChEBI] synonym: "organic hydroxy compounds" RELATED [ChEBI] is_a: CHEBI:24651 ! hydroxides is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:33832 name: organic cyclic compound namespace: chebi_ontology def: "Any organic molecule that consists of atoms connected in the form of a ring." [] subset: 3_STAR synonym: "organic cyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:33833 name: heteroarene namespace: chebi_ontology def: "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." [] subset: 3_STAR synonym: "hetarenes" RELATED [IUPAC] synonym: "heteroarenes" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33659 ! organic aromatic compound [Term] id: CHEBI:33837 name: conjugated protein namespace: chebi_ontology def: "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." [] subset: 3_STAR synonym: "complex protein" RELATED [COMe] synonym: "conjugated proteins" EXACT IUPAC_NAME [IUPAC] xref: COMe:PRX000001 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: CHEBI:33839 name: macromolecule namespace: chebi_ontology def: "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [] subset: 3_STAR synonym: "macromolecule" EXACT IUPAC_NAME [IUPAC] synonym: "macromolecules" RELATED [ChEBI] synonym: "polymer" RELATED [ChEBI] synonym: "polymer molecule" RELATED [IUPAC] synonym: "polymers" RELATED [ChEBI] xref: Wikipedia:Macromolecule is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:33853 name: phenols namespace: chebi_ontology alt_id: CHEBI:13664 alt_id: CHEBI:13825 alt_id: CHEBI:25969 alt_id: CHEBI:2857 def: "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." [] subset: 3_STAR synonym: "a phenol" RELATED [UniProt] synonym: "arenols" RELATED [IUPAC] synonym: "Aryl alcohol" RELATED [KEGG_COMPOUND] synonym: "phenols" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C15584 xref: MetaCyc:Phenols xref: Wikipedia:Phenols is_a: CHEBI:33659 ! organic aromatic compound is_a: CHEBI:33822 ! organic hydroxy compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6HOR5" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "89.072" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "89.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C(C(=C1*)*)*)*)*)O" xsd:string [Term] id: CHEBI:33893 name: reagent namespace: chebi_ontology def: "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." [] subset: 3_STAR synonym: "reactif" RELATED [IUPAC] synonym: "reactivo" RELATED [IUPAC] synonym: "reagent" EXACT IUPAC_NAME [IUPAC] synonym: "reagents" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:33917 name: aldohexose namespace: chebi_ontology alt_id: CHEBI:2558 def: "A hexose with a (potential) aldehyde group at one end." [] subset: 3_STAR synonym: "aldohexose" EXACT [ChEBI] synonym: "aldohexoses" RELATED [ChEBI] is_a: CHEBI:15693 ! aldose is_a: CHEBI:18133 ! hexose [Term] id: CHEBI:33937 name: macronutrient namespace: chebi_ontology def: "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." [] subset: 3_STAR synonym: "macronutrients" RELATED [ChEBI] is_a: CHEBI:33284 ! nutrient [Term] id: CHEBI:350546 name: serotonin(1+) namespace: chebi_ontology def: "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." [] subset: 3_STAR synonym: "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "serotonin" RELATED [UniProt] synonym: "serotonin cation" RELATED [ChEBI] is_a: CHEBI:35274 ! ammonium ion derivative relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:28790 ! serotonin property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "177.22250" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "177.10224" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccc(O)cc12" xsd:string [Term] id: CHEBI:35106 name: nitrogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "nitrogen hydrides" RELATED [ChEBI] is_a: CHEBI:35881 ! pnictogen hydride is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35107 name: azane namespace: chebi_ontology def: "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." [] subset: 3_STAR synonym: "azanes" RELATED [ChEBI] is_a: CHEBI:35106 ! nitrogen hydride [Term] id: CHEBI:35222 name: inhibitor namespace: chebi_ontology def: "A substance that diminishes the rate of a chemical reaction." [] subset: 3_STAR synonym: "inhibidor" RELATED [ChEBI] synonym: "inhibiteur" RELATED [ChEBI] synonym: "inhibitor" EXACT IUPAC_NAME [IUPAC] synonym: "inhibitors" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:35223 name: catalyst namespace: chebi_ontology def: "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." [] subset: 3_STAR synonym: "catalizador" RELATED [ChEBI] synonym: "catalyseur" RELATED [ChEBI] synonym: "catalyst" EXACT IUPAC_NAME [IUPAC] synonym: "Katalysator" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:35238 name: amino acid zwitterion namespace: chebi_ontology def: "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." [] subset: 3_STAR synonym: "amino acid zwitterion" EXACT [ChEBI] is_a: CHEBI:27369 ! zwitterion [Term] id: CHEBI:35267 name: quaternary ammonium ion namespace: chebi_ontology alt_id: CHEBI:26470 alt_id: CHEBI:8693 def: "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." [] subset: 3_STAR synonym: "a quaternary ammonium" RELATED [UniProt] synonym: "Quaternary amine" RELATED [KEGG_COMPOUND] synonym: "quaternary ammonium ion" EXACT IUPAC_NAME [IUPAC] synonym: "quaternary ammonium ions" RELATED [ChEBI] xref: KEGG:C06703 is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "NR4" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "14.00670" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "14.00307" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*][N+]([*])([*])[*]" xsd:string [Term] id: CHEBI:35274 name: ammonium ion derivative namespace: chebi_ontology def: "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." [] subset: 3_STAR synonym: "ammonium ion derivatives" RELATED [ChEBI] synonym: "azanium ion derivative" RELATED [ChEBI] synonym: "azanium ion derivatives" RELATED [ChEBI] is_a: CHEBI:33702 ! polyatomic cation is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_parent_hydride CHEBI:28938 ! ammonium [Term] id: CHEBI:35287 name: acylcholine namespace: chebi_ontology alt_id: CHEBI:13245 alt_id: CHEBI:22227 alt_id: CHEBI:2463 def: "A choline ester formed from choline and a carboxylic acid." [] subset: 3_STAR synonym: "acylcholines" RELATED [ChEBI] synonym: "an acylcholine" RELATED [UniProt] xref: KEGG:C01777 is_a: CHEBI:35267 ! quaternary ammonium ion property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C6H13NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "131.17290" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "131.09463" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[N+](C)(C)CCOC([*])=O" xsd:string [Term] id: CHEBI:35341 name: steroid namespace: chebi_ontology alt_id: CHEBI:13687 alt_id: CHEBI:26768 alt_id: CHEBI:9263 def: "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." [] subset: 3_STAR synonym: "a steroid" RELATED [UniProt] synonym: "Steroid" EXACT [KEGG_COMPOUND] synonym: "steroids" EXACT IUPAC_NAME [IUPAC] xref: KEGG:C00377 xref: MetaCyc:Steroids is_a: CHEBI:18059 ! lipid is_a: CHEBI:51958 ! organic polycyclic compound property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C19H31R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "259.450" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "259.24258" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C" xsd:string [Term] id: CHEBI:35350 name: hydroxy steroid namespace: chebi_ontology alt_id: CHEBI:24748 alt_id: CHEBI:5814 subset: 3_STAR synonym: "hydroxy steroids" RELATED [ChEBI] synonym: "Hydroxysteroid" RELATED [KEGG_COMPOUND] synonym: "hydroxysteroids" RELATED [ChEBI] xref: KEGG:C02159 is_a: CHEBI:33822 ! organic hydroxy compound is_a: CHEBI:35341 ! steroid [Term] id: CHEBI:35352 name: organonitrogen compound namespace: chebi_ontology def: "Any heteroorganic entity containing at least one carbon-nitrogen bond." [] subset: 3_STAR synonym: "organonitrogen compounds" EXACT IUPAC_NAME [IUPAC] synonym: "organonitrogens" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:51143 ! nitrogen molecular entity [Term] id: CHEBI:35381 name: monosaccharide namespace: chebi_ontology alt_id: CHEBI:25407 alt_id: CHEBI:6984 def: "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." [] subset: 3_STAR synonym: "monosacarido" RELATED [ChEBI] synonym: "monosacaridos" RELATED [IUPAC] synonym: "Monosaccharid" RELATED [ChEBI] synonym: "Monosaccharide" EXACT [KEGG_COMPOUND] synonym: "monosaccharides" EXACT IUPAC_NAME [IUPAC] synonym: "Monosacharid" RELATED [ChEBI] xref: KEGG:C06698 is_a: CHEBI:16646 ! carbohydrate [Term] id: CHEBI:35406 name: oxoanion namespace: chebi_ontology alt_id: CHEBI:33274 alt_id: CHEBI:33436 def: "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." [] subset: 3_STAR synonym: "oxoacid anions" RELATED [ChEBI] synonym: "oxoanion" EXACT [ChEBI] synonym: "oxoanions" RELATED [ChEBI] is_a: CHEBI:25741 ! oxide is_a: CHEBI:33273 ! polyatomic anion [Term] id: CHEBI:35472 name: anti-inflammatory drug namespace: chebi_ontology def: "A substance that reduces or suppresses inflammation." [] subset: 3_STAR synonym: "anti-inflammatory drugs" RELATED [ChEBI] synonym: "antiinflammatory agent" RELATED [ChEBI] synonym: "antiinflammatory drug" RELATED [ChEBI] synonym: "antiinflammatory drugs" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:67079 ! anti-inflammatory agent [Term] id: CHEBI:35479 name: alkali metal salt namespace: chebi_ontology subset: 3_STAR synonym: "alkali metal salts" RELATED [ChEBI] is_a: CHEBI:24866 ! salt is_a: CHEBI:33296 ! alkali metal molecular entity [Term] id: CHEBI:35507 name: natural product fundamental parent namespace: chebi_ontology subset: 3_STAR synonym: "natural product fundamental parents" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33245 ! organic fundamental parent [Term] id: CHEBI:35508 name: steroid fundamental parent namespace: chebi_ontology subset: 3_STAR synonym: "steroid fundamental parents" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid is_a: CHEBI:35507 ! natural product fundamental parent [Term] id: CHEBI:35519 name: cholane namespace: chebi_ontology subset: 3_STAR synonym: "cholane" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:35508 ! steroid fundamental parent property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H42" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QSHQKIURKJITMZ-BRPMRXRMSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "330.59028" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "330.32865" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC" xsd:string [Term] id: CHEBI:35524 name: sympathomimetic agent namespace: chebi_ontology def: "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." [] subset: 3_STAR synonym: "sympathomimetic" RELATED [ChEBI] synonym: "sympathomimetics" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:35554 name: cardiovascular drug namespace: chebi_ontology def: "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." [] subset: 3_STAR synonym: "cardiovascular agent" RELATED [ChEBI] synonym: "cardiovascular drugs" RELATED [ChEBI] is_a: CHEBI:23888 ! drug [Term] id: CHEBI:35569 name: alpha-adrenergic agonist namespace: chebi_ontology def: "An agent that selectively binds to and activates alpha-adrenergic receptors." [] subset: 3_STAR synonym: "alpha-adrenergic agonists" RELATED [ChEBI] synonym: "alpha-adrenergic receptor agonist" RELATED [ChEBI] synonym: "alpha-adrenoceptor agonists" RELATED [IUPHAR] is_a: CHEBI:37886 ! adrenergic agonist is_a: CHEBI:48539 ! alpha-adrenergic drug [Term] id: CHEBI:35604 name: carbon oxoanion namespace: chebi_ontology def: "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." [] subset: 3_STAR synonym: "carbon oxoanion" EXACT [ChEBI] synonym: "carbon oxoanions" RELATED [ChEBI] synonym: "oxocarbon anion" RELATED [ChEBI] synonym: "oxocarbon anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:35406 ! oxoanion is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35605 name: carbon oxoacid namespace: chebi_ontology subset: 3_STAR synonym: "carbon oxoacids" RELATED [ChEBI] synonym: "oxoacids of carbon" RELATED [ChEBI] is_a: CHEBI:24833 ! oxoacid is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35620 name: vasodilator agent namespace: chebi_ontology def: "A drug used to cause dilation of the blood vessels." [] subset: 3_STAR synonym: "vasodilator" RELATED [ChEBI] synonym: "vasodilator agents" RELATED [ChEBI] is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:35692 name: dicarboxylic acid namespace: chebi_ontology alt_id: CHEBI:23692 alt_id: CHEBI:36172 alt_id: CHEBI:4501 def: "Any carboxylic acid containing two carboxy groups." [] subset: 3_STAR synonym: "Dicarboxylic acid" EXACT [KEGG_COMPOUND] synonym: "dicarboxylic acids" RELATED [ChEBI] xref: KEGG:C02028 is_a: CHEBI:131927 ! dicarboxylic acids and O-substituted derivatives is_a: CHEBI:33575 ! carboxylic acid relationship: is_conjugate_acid_of CHEBI:35693 ! dicarboxylic acid anion [Term] id: CHEBI:35693 name: dicarboxylic acid anion namespace: chebi_ontology subset: 3_STAR synonym: "dicarboxylic acid anion" EXACT [ChEBI] synonym: "dicarboxylic acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:35692 ! dicarboxylic acid [Term] id: CHEBI:35701 name: ester namespace: chebi_ontology alt_id: CHEBI:23960 alt_id: CHEBI:4859 def: "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." [] subset: 3_STAR synonym: "Ester" EXACT [KEGG_COMPOUND] synonym: "esters" RELATED [ChEBI] xref: KEGG:C00287 xref: Wikipedia:Ester is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:35722 name: sulfated glycosaminoglycan namespace: chebi_ontology subset: 3_STAR synonym: "glycosaminoglycan sulfate" RELATED [ChEBI] synonym: "glycosaminoglycan sulfates" RELATED [ChEBI] synonym: "sulfated glycosaminoglycans" RELATED [ChEBI] is_a: CHEBI:18085 ! glycosaminoglycan is_a: CHEBI:35724 ! carbohydrate sulfate [Term] id: CHEBI:35724 name: carbohydrate sulfate namespace: chebi_ontology subset: 3_STAR synonym: "carbohydrate sulfates" RELATED [ChEBI] synonym: "carbohydrate sulphates" RELATED [ChEBI] is_a: CHEBI:25704 ! organic sulfate is_a: CHEBI:26819 ! sulfuric ester is_a: CHEBI:63299 ! carbohydrate derivative [Term] id: CHEBI:35757 name: monocarboxylic acid anion namespace: chebi_ontology alt_id: CHEBI:13657 alt_id: CHEBI:25382 alt_id: CHEBI:3407 def: "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." [] subset: 3_STAR synonym: "a monocarboxylate" RELATED [UniProt] synonym: "Carboxylate" RELATED [KEGG_COMPOUND] synonym: "Monocarboxylate" RELATED [KEGG_COMPOUND] synonym: "monocarboxylates" RELATED [ChEBI] synonym: "monocarboxylic acid anions" RELATED [ChEBI] xref: KEGG:C00060 is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:25384 ! monocarboxylic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "44.01000" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "43.98983" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([*])=O" xsd:string [Term] id: CHEBI:35780 name: phosphate ion namespace: chebi_ontology def: "A phosphorus oxoanion that is the conjugate base of phosphoric acid." [] subset: 3_STAR synonym: "phosphate" RELATED [ChEBI] synonym: "phosphate ions" RELATED [ChEBI] synonym: "Pi" RELATED [ChEBI] is_a: CHEBI:33461 ! phosphorus oxoanion relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:26078 ! phosphoric acid [Term] id: CHEBI:35881 name: pnictogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "pnictogen hydride" EXACT [ChEBI] synonym: "pnictogen hydrides" RELATED [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33302 ! pnictogen molecular entity [Term] id: CHEBI:35942 name: neurotransmitter agent namespace: chebi_ontology def: "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." [] subset: 3_STAR synonym: "neurotransmitter agents" RELATED [ChEBI] is_a: CHEBI:23888 ! drug is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:36078 name: cholanoid namespace: chebi_ontology alt_id: CHEBI:22867 alt_id: CHEBI:50419 subset: 3_STAR synonym: "bile acids and derivatives" RELATED [LIPID_MAPS] synonym: "cholanoids" RELATED [ChEBI] xref: LIPID_MAPS_class:LMST04 {source="LIPID MAPS"} is_a: CHEBI:35341 ! steroid relationship: has_parent_hydride CHEBI:35519 ! cholane [Term] id: CHEBI:36080 name: protein namespace: chebi_ontology alt_id: CHEBI:13677 alt_id: CHEBI:14911 def: "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." [] subset: 3_STAR synonym: "proteins" EXACT IUPAC_NAME [IUPAC] is_a: PR:000000001 ! protein equivalent_to: PR:000000001 ! protein [Term] id: CHEBI:36235 name: bile acid anion namespace: chebi_ontology subset: 3_STAR synonym: "bile acid anions" RELATED [ChEBI] is_a: CHEBI:35757 ! monocarboxylic acid anion is_a: CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:36237 name: cholanic acid namespace: chebi_ontology def: "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." [] subset: 3_STAR synonym: "cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] xref: CAS:25312-65-6 {source="ChemIDplus"} xref: Patent:JP2008069152 xref: Reaxys:13246008 {source="Reaxys"} is_a: CHEBI:36278 ! cholanic acids property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-KBMWBBLPSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O" xsd:string [Term] id: CHEBI:36238 name: 5beta-cholanic acid namespace: chebi_ontology subset: 3_STAR synonym: "(5beta)-cholan-24-oic acid" RELATED [ChemIDplus] synonym: "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid" RELATED [ChemIDplus] synonym: "5beta-cholan-24-oic acid" EXACT IUPAC_NAME [IUPAC] synonym: "5beta-cholanic acid" EXACT [ChemIDplus] synonym: "5beta-cholanoic acid" RELATED [ChemIDplus] synonym: "ursocholanic acid" RELATED [ChemIDplus] xref: Beilstein:3214794 {source="Beilstein"} xref: CAS:546-18-9 {source="ChemIDplus"} xref: LIPID_MAPS_instance:LMST04010441 {source="LIPID MAPS"} is_a: CHEBI:36237 ! cholanic acid is_a: CHEBI:36248 ! 5beta-cholanic acids property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C24H40O2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "RPKLZQLYODPWTM-LVVAJZGHSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "360.57320" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "360.30283" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O" xsd:string [Term] id: CHEBI:36248 name: 5beta-cholanic acids namespace: chebi_ontology def: "Members of the class of cholanic acids based on a 5beta-cholane skeleton." [] subset: 3_STAR is_a: CHEBI:136889 ! 5beta steroid is_a: CHEBI:36278 ! cholanic acids relationship: has_parent_hydride CHEBI:20664 ! 5beta-cholane [Term] id: CHEBI:36277 name: bile acid salt namespace: chebi_ontology def: "A salt of a bile acid." [] subset: 3_STAR synonym: "bile acid salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:36078 ! cholanoid [Term] id: CHEBI:36278 name: cholanic acids namespace: chebi_ontology alt_id: CHEBI:23166 alt_id: CHEBI:23211 subset: 1_STAR is_a: CHEBI:36078 ! cholanoid is_a: CHEBI:47891 ! steroid acid [Term] id: CHEBI:36338 name: lepton namespace: chebi_ontology def: "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." [] subset: 3_STAR synonym: "leptons" RELATED [ChEBI] is_a: CHEBI:33233 ! fundamental particle is_a: CHEBI:36340 ! fermion [Term] id: CHEBI:36339 name: baryon namespace: chebi_ontology def: "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." [] subset: 3_STAR synonym: "baryons" RELATED [ChEBI] is_a: CHEBI:36340 ! fermion is_a: CHEBI:36344 ! hadron [Term] id: CHEBI:36340 name: fermion namespace: chebi_ontology def: "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." [] subset: 3_STAR synonym: "fermion" EXACT IUPAC_NAME [IUPAC] synonym: "fermions" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36341 name: boson namespace: chebi_ontology def: "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." [] subset: 3_STAR synonym: "boson" EXACT IUPAC_NAME [IUPAC] synonym: "bosons" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36342 name: subatomic particle namespace: chebi_ontology def: "A particle smaller than an atom." [] subset: 3_STAR synonym: "subatomic particles" RELATED [ChEBI] xref: Wikipedia:Subatomic_particle [Term] id: CHEBI:36343 name: composite particle namespace: chebi_ontology def: "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." [] subset: 3_STAR synonym: "composite particles" RELATED [ChEBI] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36344 name: hadron namespace: chebi_ontology def: "Hadron is a subatomic particle which experiences the strong force." [] subset: 3_STAR synonym: "hadrons" RELATED [ChEBI] is_a: CHEBI:36343 ! composite particle [Term] id: CHEBI:36347 name: nuclear particle namespace: chebi_ontology def: "A nucleus or any of its constituents in any of their energy states." [] subset: 3_STAR synonym: "nuclear particle" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36342 ! subatomic particle [Term] id: CHEBI:36357 name: polyatomic entity namespace: chebi_ontology def: "Any molecular entity consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic entities" RELATED [ChEBI] is_a: CHEBI:23367 ! molecular entity relationship: has_part CHEBI:24433 ! group [Term] id: CHEBI:36358 name: polyatomic ion namespace: chebi_ontology def: "An ion consisting of more than one atom." [] subset: 3_STAR synonym: "polyatomic ions" RELATED [ChEBI] is_a: CHEBI:24870 ! ion is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:36359 name: phosphorus oxoacid derivative namespace: chebi_ontology subset: 3_STAR synonym: "phosphorus oxoacid derivative" EXACT [ChEBI] is_a: CHEBI:33241 ! oxoacid derivative is_a: CHEBI:36360 ! phosphorus oxoacids and derivatives relationship: has_functional_parent CHEBI:33457 ! phosphorus oxoacid [Term] id: CHEBI:36360 name: phosphorus oxoacids and derivatives namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:26082 ! phosphorus molecular entity [Term] id: CHEBI:36586 name: carbonyl compound namespace: chebi_ontology def: "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." [] subset: 3_STAR synonym: "carbonyl compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:36587 ! organic oxo compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23019 ! carbonyl group [Term] id: CHEBI:36587 name: organic oxo compound namespace: chebi_ontology def: "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." [] subset: 3_STAR synonym: "organic oxo compounds" RELATED [ChEBI] synonym: "oxo compounds" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:72695 ! organic molecule relationship: has_part CHEBI:46629 ! oxo group [Term] id: CHEBI:36735 name: biladienes namespace: chebi_ontology def: "Compounds based on a biladiene skeleton." [] subset: 3_STAR is_a: CHEBI:25046 ! linear tetrapyrrole [Term] id: CHEBI:36902 name: chalcogen hydride namespace: chebi_ontology subset: 3_STAR synonym: "chalcogen hydride" EXACT [ChEBI] synonym: "chalcogen hydrides" RELATED [ChEBI] is_a: CHEBI:33242 ! inorganic hydride is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36914 name: inorganic ion namespace: chebi_ontology subset: 3_STAR synonym: "inorganic ions" RELATED [ChEBI] is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36915 name: inorganic cation namespace: chebi_ontology subset: 3_STAR synonym: "inorganic cations" RELATED [ChEBI] is_a: CHEBI:36914 ! inorganic ion is_a: CHEBI:36916 ! cation [Term] id: CHEBI:36916 name: cation namespace: chebi_ontology alt_id: CHEBI:23058 alt_id: CHEBI:3473 def: "A monoatomic or polyatomic species having one or more elementary charges of the proton." [] subset: 3_STAR synonym: "Cation" EXACT [KEGG_COMPOUND] synonym: "cation" EXACT IUPAC_NAME [IUPAC] synonym: "cation" EXACT [ChEBI] synonym: "cationes" RELATED [ChEBI] synonym: "cations" RELATED [ChEBI] synonym: "Kation" RELATED [ChEBI] synonym: "Kationen" RELATED [ChEBI] xref: KEGG:C01373 is_a: CHEBI:24870 ! ion [Term] id: CHEBI:36961 name: chalcocarbonic acid namespace: chebi_ontology subset: 3_STAR synonym: "chalcocarbonic acid" EXACT [ChEBI] synonym: "chalcocarbonic acids" EXACT IUPAC_NAME [IUPAC] synonym: "chalcocarbonic acids" RELATED [ChEBI] is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:36962 name: organochalcogen compound namespace: chebi_ontology def: "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." [] subset: 3_STAR synonym: "organochalcogen compound" EXACT [ChEBI] synonym: "organochalcogen compounds" RELATED [ChEBI] is_a: CHEBI:33285 ! heteroorganic entity is_a: CHEBI:33304 ! chalcogen molecular entity [Term] id: CHEBI:36963 name: organooxygen compound namespace: chebi_ontology def: "An organochalcogen compound containing at least one carbon-oxygen bond." [] subset: 3_STAR synonym: "organooxygen compound" EXACT [ChEBI] synonym: "organooxygen compounds" RELATED [ChEBI] xref: PMID:17586126 {source="Europe PMC"} is_a: CHEBI:25806 ! oxygen molecular entity is_a: CHEBI:36962 ! organochalcogen compound [Term] id: CHEBI:37022 name: amino-acid anion namespace: chebi_ontology subset: 3_STAR synonym: "amino acid anions" RELATED [ChEBI] synonym: "amino-acid anion" EXACT [ChEBI] synonym: "amino-acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion is_a: CHEBI:35352 ! organonitrogen compound relationship: is_conjugate_base_of CHEBI:33709 ! amino acid [Term] id: CHEBI:37163 name: glucan namespace: chebi_ontology alt_id: CHEBI:24255 alt_id: CHEBI:5392 def: "A polysaccharide composed of glucose residues." [] subset: 3_STAR synonym: "Glucan" EXACT [KEGG_COMPOUND] synonym: "glucan" EXACT IUPAC_NAME [IUPAC] synonym: "glucans" RELATED [ChEBI] xref: CAS:9037-91-6 {source="ChemIDplus"} xref: KEGG:C01379 is_a: CHEBI:37164 ! homopolysaccharide property_value: http://purl.obolibrary.org/obo/chebi/formula "C12H22O11(C6H10O5)n" xsd:string [Term] id: CHEBI:37164 name: homopolysaccharide namespace: chebi_ontology def: "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." [] subset: 3_STAR synonym: "homoglycan" RELATED [IUPAC] synonym: "homopolysaccharide" EXACT IUPAC_NAME [IUPAC] synonym: "homopolysaccharides" RELATED [ChEBI] is_a: CHEBI:18154 ! polysaccharide [Term] id: CHEBI:37175 name: organic hydride namespace: chebi_ontology subset: 3_STAR synonym: "organic hydrides" RELATED [ChEBI] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37176 name: mononuclear parent hydride namespace: chebi_ontology subset: 3_STAR synonym: "mononuclear hydride" RELATED [ChEBI] synonym: "mononuclear hydrides" RELATED [IUPAC] synonym: "mononuclear parent hydrides" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:33692 ! hydrides [Term] id: CHEBI:37246 name: elemental sodium namespace: chebi_ontology subset: 3_STAR is_a: CHEBI:26712 ! sodium molecular entity [Term] id: CHEBI:37395 name: mucopolysaccharide namespace: chebi_ontology alt_id: CHEBI:25425 alt_id: CHEBI:7011 def: "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." [] subset: 3_STAR synonym: "mucopolisacarido" RELATED [ChEBI] synonym: "mucopolisacaridos" RELATED [IUPAC] synonym: "Mucopolysaccharid" RELATED [ChEBI] synonym: "Mucopolysaccharide" EXACT [KEGG_COMPOUND] synonym: "mucopolysaccharides" EXACT IUPAC_NAME [IUPAC] synonym: "Mukopolysaccharid" RELATED [ChEBI] xref: KEGG:C05114 is_a: CHEBI:18085 ! glycosaminoglycan [Term] id: CHEBI:37527 name: acid namespace: chebi_ontology alt_id: CHEBI:13800 alt_id: CHEBI:13801 alt_id: CHEBI:22209 alt_id: CHEBI:2426 def: "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." [] subset: 3_STAR synonym: "Acid" EXACT [KEGG_COMPOUND] synonym: "acid" EXACT IUPAC_NAME [IUPAC] synonym: "acide" RELATED [IUPAC] synonym: "acido" RELATED [ChEBI] synonym: "acids" RELATED [ChEBI] synonym: "Saeure" RELATED [ChEBI] synonym: "Saeuren" RELATED [ChEBI] xref: KEGG:C00174 is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:37577 name: heteroatomic molecular entity namespace: chebi_ontology def: "A molecular entity consisting of two or more chemical elements." [] subset: 3_STAR synonym: "chemical compound" RELATED [ChEBI] synonym: "heteroatomic molecular entities" RELATED [ChEBI] is_a: CHEBI:36357 ! polyatomic entity [Term] id: CHEBI:37622 name: carboxamide namespace: chebi_ontology alt_id: CHEBI:35354 alt_id: CHEBI:35355 def: "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." [] subset: 3_STAR synonym: "carboxamides" EXACT IUPAC_NAME [IUPAC] synonym: "carboxamides" RELATED [ChEBI] synonym: "primary carboxamide" RELATED [ChEBI] is_a: CHEBI:33256 ! primary amide is_a: CHEBI:35352 ! organonitrogen compound is_a: CHEBI:36963 ! organooxygen compound relationship: has_part CHEBI:23004 ! carbamoyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CNOR3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "42.01680" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "41.99799" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[*]C(=O)N([*])[*]" xsd:string [Term] id: CHEBI:37826 name: sulfuric acid derivative namespace: chebi_ontology subset: 3_STAR synonym: "sulfuric acid derivative" EXACT [ChEBI] synonym: "sulfuric acid derivatives" RELATED [ChEBI] is_a: CHEBI:33424 ! sulfur oxoacid derivative relationship: has_functional_parent CHEBI:26836 ! sulfuric acid [Term] id: CHEBI:37838 name: carboacyl group namespace: chebi_ontology def: "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." [] subset: 3_STAR synonym: "carboacyl groups" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl group" EXACT IUPAC_NAME [IUPAC] synonym: "carboxylic acyl groups" RELATED [IUPAC] is_a: CHEBI:22221 ! acyl group relationship: is_substituent_group_from CHEBI:33575 ! carboxylic acid [Term] id: CHEBI:37886 name: adrenergic agonist namespace: chebi_ontology def: "An agent that selectively binds to and activates adrenergic receptors." [] subset: 3_STAR synonym: "adrenergic agonists" RELATED [ChEBI] synonym: "adrenergic receptor agonist" RELATED [ChEBI] synonym: "adrenoceptor agonists" RELATED [IUPHAR] synonym: "adrenomimetic" RELATED [ChEBI] synonym: "adrenomimetics" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:37962 name: adrenergic agent namespace: chebi_ontology def: "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." [] subset: 3_STAR synonym: "adrenergic agents" RELATED [ChEBI] synonym: "adrenergic drug" RELATED [ChEBI] synonym: "adrenergic drugs" RELATED [ChEBI] synonym: "adrenergic neuron agents" RELATED [ChEBI] synonym: "adrenergics" RELATED [ChEBI] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38077 name: polypyrrole namespace: chebi_ontology def: "A compound composed of two or more pyrrole units." [] subset: 3_STAR synonym: "poly(pyrrole)s" RELATED [ChEBI] synonym: "polypyrroles" RELATED [ChEBI] synonym: "PPys" RELATED [ChEBI] xref: Beilstein:8538310 {source="Beilstein"} is_a: CHEBI:38101 ! organonitrogen heterocyclic compound [Term] id: CHEBI:38101 name: organonitrogen heterocyclic compound namespace: chebi_ontology def: "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." [] subset: 3_STAR synonym: "heterocyclic organonitrogen compounds" RELATED [ChEBI] synonym: "organonitrogen heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:35352 ! organonitrogen compound [Term] id: CHEBI:38166 name: organic heteropolycyclic compound namespace: chebi_ontology alt_id: CHEBI:25429 alt_id: CHEBI:38075 subset: 3_STAR synonym: "organic heteropolycyclic compounds" RELATED [ChEBI] is_a: CHEBI:24532 ! organic heterocyclic compound is_a: CHEBI:33671 ! heteropolycyclic compound [Term] id: CHEBI:38180 name: polycyclic heteroarene namespace: chebi_ontology subset: 3_STAR synonym: "polycyclic heteroarenes" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene [Term] id: CHEBI:38323 name: cholinergic drug namespace: chebi_ontology def: "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." [] subset: 3_STAR synonym: "cholinergic agent" RELATED [ChEBI] synonym: "cholinergic drugs" RELATED [ChEBI] synonym: "cholinomimetic" RELATED [ChEBI] is_a: CHEBI:35942 ! neurotransmitter agent [Term] id: CHEBI:38324 name: cholinergic agonist namespace: chebi_ontology def: "Any drug that binds to and activates cholinergic receptors." [] subset: 3_STAR synonym: "acetylcholine agonist" RELATED [ChEBI] synonym: "acetylcholine agonists" RELATED [ChEBI] synonym: "acetylcholine receptor agonist" RELATED [IUPHAR] synonym: "cholinergic agonists" RELATED [ChEBI] synonym: "cholinomimetic" RELATED [ChEBI] synonym: "cholinomimetics" RELATED [ChEBI] is_a: CHEBI:38323 ! cholinergic drug [Term] id: CHEBI:38325 name: muscarinic agonist namespace: chebi_ontology def: "Any drug that binds to and activates a muscarinic cholinergic receptor." [] subset: 3_STAR synonym: "muscarinic acetylcholine receptor agonist" RELATED [ChEBI] synonym: "muscarinic agonists" RELATED [ChEBI] synonym: "muscarinic cholinergic agonist" RELATED [ChEBI] synonym: "muscarinic cholinergic agonists" RELATED [ChEBI] is_a: CHEBI:38324 ! cholinergic agonist [Term] id: CHEBI:38631 name: aminoalkylindole namespace: chebi_ontology alt_id: CHEBI:22503 alt_id: CHEBI:24792 subset: 3_STAR synonym: "aminoalkylindoles" RELATED [ChEBI] is_a: CHEBI:24828 ! indoles [Term] id: CHEBI:38700 name: organic sodium salt namespace: chebi_ontology subset: 3_STAR synonym: "organic sodium salt" EXACT [ChEBI] synonym: "organic sodium salts" RELATED [ChEBI] is_a: CHEBI:24868 ! organic salt is_a: CHEBI:26714 ! sodium salt [Term] id: CHEBI:38716 name: carboxylic acid dianion namespace: chebi_ontology def: "Any dianion containing at least one carboxy group." [] subset: 3_STAR synonym: "carboxylic acid dianion" EXACT [ChEBI] synonym: "carboxylic acid dianions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion [Term] id: CHEBI:38958 name: indole alkaloid namespace: chebi_ontology alt_id: CHEBI:24795 alt_id: CHEBI:5901 def: "An alkaloid containing an indole skeleton." [] subset: 3_STAR synonym: "Indole alkaloid" EXACT [KEGG_COMPOUND] synonym: "indole alkaloids" RELATED [ChEBI] xref: KEGG:C06073 xref: Wikipedia:Indole_alkaloid is_a: CHEBI:22315 ! alkaloid relationship: has_part CHEBI:73398 ! indole skeleton [Term] id: CHEBI:39141 name: Bronsted acid namespace: chebi_ontology def: "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." [] subset: 3_STAR synonym: "acide de Bronsted" RELATED [IUPAC] synonym: "Bronsted acid" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Saeure" RELATED [ChEBI] synonym: "donneur d'hydron" RELATED [IUPAC] synonym: "hydron donor" RELATED [IUPAC] is_a: CHEBI:17891 ! donor is_a: CHEBI:37527 ! acid [Term] id: CHEBI:39142 name: Bronsted base namespace: chebi_ontology def: "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." [] subset: 3_STAR synonym: "accepteur d'hydron" RELATED [IUPAC] synonym: "base de Bronsted" RELATED [IUPAC] synonym: "Bronsted base" EXACT IUPAC_NAME [IUPAC] synonym: "Bronsted-Base" RELATED [ChEBI] synonym: "hydron acceptor" RELATED [IUPAC] is_a: CHEBI:15339 ! acceptor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39144 name: Lewis base namespace: chebi_ontology def: "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." [] subset: 3_STAR synonym: "base de Lewis" RELATED [IUPAC] synonym: "donneur d'une paire d'electrons" RELATED [ChEBI] synonym: "electron donor" RELATED [ChEBI] synonym: "Lewis base" EXACT IUPAC_NAME [IUPAC] synonym: "Lewis-Base" RELATED [ChEBI] is_a: CHEBI:17891 ! donor is_a: CHEBI:22695 ! base [Term] id: CHEBI:39745 name: dihydrogenphosphate namespace: chebi_ontology alt_id: CHEBI:29137 alt_id: CHEBI:39739 def: "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." [] subset: 3_STAR synonym: "[PO2(OH)2](-)" RELATED [IUPAC] synonym: "dihydrogen(tetraoxidophosphate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydrogenphosphate" EXACT IUPAC_NAME [IUPAC] synonym: "DIHYDROGENPHOSPHATE ION" RELATED [PDBeChem] synonym: "dihydrogentetraoxophosphate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] synonym: "dihydroxidodioxidophosphate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "H2PO4(-)" RELATED [IUPAC] xref: DrugBank:DB02831 xref: Gmelin:1999 {source="Gmelin"} xref: PDBeChem:2HP is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79389 ! monovalent inorganic anion relationship: is_conjugate_acid_of CHEBI:43474 ! hydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H2O4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.98724" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96962" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OP([O-])(=O)O[H]" xsd:string [Term] id: CHEBI:41609 name: carbonate namespace: chebi_ontology alt_id: CHEBI:29201 alt_id: CHEBI:41605 subset: 3_STAR synonym: "[CO3](2-)" RELATED [IUPAC] synonym: "carbonate" EXACT [IUPAC] synonym: "CARBONATE ION" RELATED [PDBeChem] synonym: "CO3(2-)" RELATED [ChEBI] synonym: "Karbonat" RELATED [ChEBI] synonym: "trioxidocarbonate(2-)" EXACT IUPAC_NAME [IUPAC] xref: Beilstein:3600898 {source="Beilstein"} xref: CAS:3812-32-6 {source="ChemIDplus"} xref: Gmelin:1559 {source="Gmelin"} xref: PDBeChem:CO3 is_a: CHEBI:35604 ! carbon oxoanion relationship: is_conjugate_base_of CHEBI:17544 ! hydrogencarbonate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "60.00890" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.98584" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]C([O-])=O" xsd:string [Term] id: CHEBI:43176 name: hydroxy group namespace: chebi_ontology alt_id: CHEBI:24706 alt_id: CHEBI:43171 subset: 3_STAR synonym: "-OH" RELATED [IUPAC] synonym: "hydroxy" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROXY GROUP" EXACT [PDBeChem] synonym: "hydroxy group" EXACT [UniProt] synonym: "hydroxyl" RELATED [ChEBI] synonym: "hydroxyl group" RELATED [ChEBI] xref: PDBeChem:OH is_a: CHEBI:33246 ! inorganic group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.00734" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.00274" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*O[H]" xsd:string [Term] id: CHEBI:43474 name: hydrogenphosphate namespace: chebi_ontology alt_id: CHEBI:29139 alt_id: CHEBI:43470 def: "A phosphate ion that is the conjugate base of dihydrogenphosphate." [] subset: 3_STAR synonym: "[P(OH)O3](2-)" RELATED [MolBase] synonym: "[PO3(OH)](2-)" RELATED [IUPAC] synonym: "HPO4(2-)" RELATED [IUPAC] synonym: "hydrogen phosphate" RELATED [ChEBI] synonym: "hydrogen(tetraoxidophosphate)(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogenphosphate" EXACT IUPAC_NAME [IUPAC] synonym: "HYDROGENPHOSPHATE ION" RELATED [PDBeChem] synonym: "hydrogentetraoxophosphate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxophosphate(V)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidotrioxidophosphate(2-)" EXACT IUPAC_NAME [IUPAC] synonym: "INORGANIC PHOSPHATE GROUP" RELATED [PDBeChem] synonym: "phosphate" RELATED [UniProt] xref: Gmelin:1998 {source="Gmelin"} xref: MolBase:1628 xref: PDBeChem:PI xref: PDBeChem:PO4 is_a: CHEBI:35780 ! phosphate ion is_a: CHEBI:79388 ! divalent inorganic anion relationship: has_role CHEBI:23357 ! cofactor relationship: has_role CHEBI:75772 ! Saccharomyces cerevisiae metabolite relationship: is_conjugate_acid_of CHEBI:18367 ! phosphate(3-) relationship: is_conjugate_base_of CHEBI:39745 ! dihydrogenphosphate property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4P" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "95.97930" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.96234" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "OP([O-])([O-])=O" xsd:string [Term] id: CHEBI:45696 name: hydrogensulfate namespace: chebi_ontology alt_id: CHEBI:29199 alt_id: CHEBI:45693 subset: 3_STAR synonym: "[SO3(OH)](-)" RELATED [IUPAC] synonym: "HSO4(-)" RELATED [IUPAC] synonym: "HYDROGEN SULFATE" RELATED [PDBeChem] synonym: "hydrogen(tetraoxidosulfate)(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogensulfate" EXACT [IUPAC] synonym: "hydrogensulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(1-)" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogentetraoxosulfate(VI)" EXACT IUPAC_NAME [IUPAC] synonym: "hydroxidotrioxidosulfate(1-)" EXACT IUPAC_NAME [IUPAC] xref: Gmelin:2121 {source="Gmelin"} is_a: CHEBI:33482 ! sulfur oxoanion relationship: is_conjugate_acid_of CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:26836 ! sulfuric acid property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "HO4S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "QAOWNCQODCNURD-UHFFFAOYSA-M" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "97.07154" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "96.96010" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]OS([O-])(=O)=O" xsd:string [Term] id: CHEBI:46629 name: oxo group namespace: chebi_ontology alt_id: CHEBI:29353 alt_id: CHEBI:44607 subset: 3_STAR synonym: "=O" RELATED [IUPAC] synonym: "oxo" EXACT IUPAC_NAME [IUPAC] synonym: "OXO GROUP" EXACT [PDBeChem] xref: PDBeChem:O is_a: CHEBI:33246 ! inorganic group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "15.99940" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "15.99491" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "O=*" xsd:string [Term] id: CHEBI:46662 name: mineral namespace: chebi_ontology def: "In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals')." [] subset: 3_STAR synonym: "mineral" EXACT [ChEBI] synonym: "Minerale" RELATED [ChEBI] synonym: "minerales" RELATED [ChEBI] synonym: "minerals" RELATED [ChEBI] synonym: "mineraux" RELATED [ChEBI] xref: Wikipedia:Mineral is_a: CHEBI:59999 ! chemical substance [Term] id: CHEBI:46723 name: phosphate mineral namespace: chebi_ontology subset: 3_STAR synonym: "phosphate minerals" RELATED [ChEBI] is_a: CHEBI:46662 ! mineral [Term] id: CHEBI:46787 name: solvent namespace: chebi_ontology def: "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." [] subset: 3_STAR synonym: "Loesungsmittel" RELATED [ChEBI] synonym: "solvant" RELATED [ChEBI] synonym: "solvents" RELATED [ChEBI] xref: Wikipedia:Solvent is_a: CHEBI:33232 ! application is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:46883 name: carboxy group namespace: chebi_ontology alt_id: CHEBI:23025 alt_id: CHEBI:41420 subset: 3_STAR synonym: "-C(O)OH" RELATED [IUPAC] synonym: "-CO2H" RELATED [ChEBI] synonym: "-COOH" RELATED [IUPAC] synonym: "carboxy" EXACT IUPAC_NAME [IUPAC] synonym: "CARBOXY GROUP" EXACT [PDBeChem] synonym: "carboxyl group" RELATED [ChEBI] xref: PDBeChem:FMT is_a: CHEBI:33249 ! organyl group property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "CHO2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "45.01744" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "44.99765" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "*C(=O)O" xsd:string [Term] id: CHEBI:47622 name: acetate ester namespace: chebi_ontology alt_id: CHEBI:13244 alt_id: CHEBI:13799 alt_id: CHEBI:22189 alt_id: CHEBI:2406 def: "Any carboxylic ester where the carboxylic acid component is acetic acid." [] subset: 3_STAR synonym: "acetate" RELATED [ChEBI] synonym: "acetate esters" RELATED [ChEBI] synonym: "acetates" RELATED [ChEBI] synonym: "Acetic ester" RELATED [KEGG_COMPOUND] synonym: "Acetyl ester" RELATED [KEGG_COMPOUND] synonym: "acetyl esters" RELATED [ChEBI] synonym: "an acetyl ester" RELATED [UniProt] xref: KEGG:C01883 xref: Wikipedia:Acetate#Esters is_a: CHEBI:33308 ! carboxylic ester relationship: has_functional_parent CHEBI:15366 ! acetic acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H3O2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "59.04400" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "59.01330" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC(=O)O[*]" xsd:string [Term] id: CHEBI:47891 name: steroid acid namespace: chebi_ontology def: "Any steroid substituted by at least one carboxy group." [] subset: 3_STAR synonym: "steroid acids" RELATED [ChEBI] is_a: CHEBI:35341 ! steroid is_a: CHEBI:64709 ! organic acid relationship: is_conjugate_acid_of CHEBI:50160 ! steroid acid anion [Term] id: CHEBI:48154 name: sulfur oxide namespace: chebi_ontology subset: 3_STAR synonym: "oxides of sulfur" RELATED [ChEBI] synonym: "Schwefeloxide" RELATED [ChEBI] synonym: "sulfur oxides" RELATED [ChEBI] is_a: CHEBI:24836 ! inorganic oxide is_a: CHEBI:26835 ! sulfur molecular entity [Term] id: CHEBI:48354 name: polar solvent namespace: chebi_ontology def: "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." [] subset: 3_STAR synonym: "polar solvent" EXACT IUPAC_NAME [IUPAC] synonym: "polar solvents" RELATED [ChEBI] is_a: CHEBI:46787 ! solvent [Term] id: CHEBI:48356 name: protic solvent namespace: chebi_ontology def: "A polar solvent that is capable of acting as a hydron (proton) donor." [] subset: 3_STAR synonym: "protogenic solvent" EXACT IUPAC_NAME [IUPAC] is_a: CHEBI:39141 ! Bronsted acid is_a: CHEBI:48354 ! polar solvent [Term] id: CHEBI:48539 name: alpha-adrenergic drug namespace: chebi_ontology def: "Any drug that acts on an alpha-adrenergic receptor." [] subset: 3_STAR synonym: "alpha-adrenergic drugs" RELATED [ChEBI] is_a: CHEBI:37962 ! adrenergic agent [Term] id: CHEBI:48705 name: agonist namespace: chebi_ontology def: "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." [] subset: 3_STAR synonym: "agonist" EXACT IUPAC_NAME [IUPAC] synonym: "agonista" RELATED [ChEBI] synonym: "agoniste" RELATED [ChEBI] synonym: "agonists" RELATED [ChEBI] is_a: CHEBI:52210 ! pharmacological role [Term] id: CHEBI:49637 name: hydrogen atom namespace: chebi_ontology alt_id: CHEBI:24634 alt_id: CHEBI:49636 subset: 3_STAR synonym: "1H" RELATED [IUPAC] synonym: "H" RELATED [IUPAC] synonym: "hidrogeno" RELATED [ChEBI] synonym: "hydrogen" EXACT IUPAC_NAME [IUPAC] synonym: "hydrogen" RELATED [ChEBI] synonym: "hydrogene" RELATED [ChEBI] synonym: "Wasserstoff" RELATED [ChEBI] xref: WebElements:H is_a: CHEBI:24835 ! inorganic molecular entity is_a: CHEBI:25585 ! nonmetal atom is_a: CHEBI:33559 ! s-block element atom relationship: has_role CHEBI:33937 ! macronutrient property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/H" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1.00794" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1.00783" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[H]" xsd:string [Term] id: CHEBI:50047 name: organic amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." [] subset: 3_STAR synonym: "organic amino compounds" RELATED [ChEBI] is_a: CHEBI:35352 ! organonitrogen compound relationship: has_parent_hydride CHEBI:16134 ! ammonia relationship: has_role CHEBI:39142 ! Bronsted base [Term] id: CHEBI:50160 name: steroid acid anion namespace: chebi_ontology def: "Any anion formed by loss of a proton from a steroid acid." [] subset: 3_STAR synonym: "steroid acid anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: is_conjugate_base_of CHEBI:47891 ! steroid acid [Term] id: CHEBI:50297 name: canonical nucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical nucleotide residues" RELATED [ChEBI] is_a: CHEBI:50319 ! nucleotide residue [Term] id: CHEBI:50298 name: canonical deoxyribonucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical deoxyribonucleotide residues" RELATED [ChEBI] is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50299 name: canonical ribonucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "canonical ribonucleotide residues" RELATED [ChEBI] is_a: CHEBI:50297 ! canonical nucleotide residue [Term] id: CHEBI:50312 name: onium compound namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:37577 ! heteroatomic molecular entity [Term] id: CHEBI:50313 name: onium cation namespace: chebi_ontology def: "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." [] subset: 3_STAR synonym: "onium cations" EXACT IUPAC_NAME [IUPAC] synonym: "onium cations" RELATED [ChEBI] synonym: "onium ion" RELATED [ChEBI] synonym: "onium ions" RELATED [ChEBI] is_a: CHEBI:50312 ! onium compound [Term] id: CHEBI:50319 name: nucleotide residue namespace: chebi_ontology subset: 3_STAR synonym: "nucleotide residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50320 name: nucleoside residue namespace: chebi_ontology subset: 3_STAR synonym: "nucleoside residues" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:50514 name: vasoconstrictor agent namespace: chebi_ontology def: "Drug used to cause constriction of the blood vessels." [] subset: 3_STAR is_a: CHEBI:35554 ! cardiovascular drug [Term] id: CHEBI:50860 name: organic molecular entity namespace: chebi_ontology alt_id: CHEBI:25700 alt_id: CHEBI:33244 def: "Any molecular entity that contains carbon." [] subset: 3_STAR synonym: "organic compounds" RELATED [ChEBI] synonym: "organic entity" RELATED [ChEBI] synonym: "organic molecular entities" RELATED [ChEBI] is_a: CHEBI:33582 ! carbon group molecular entity relationship: has_part CHEBI:27594 ! carbon atom [Term] id: CHEBI:50906 name: role namespace: chebi_ontology def: "A role is particular behaviour which a material entity may exhibit." [] subset: 3_STAR is_a: BFO:0000023 ! role [Term] id: CHEBI:50910 name: neurotoxin namespace: chebi_ontology alt_id: CHEBI:50911 def: "A poison that interferes with the functions of the nervous system." [] subset: 3_STAR synonym: "agente neurotoxico" RELATED [ChEBI] synonym: "nerve poison" RELATED [ChEBI] synonym: "nerve poisons" RELATED [ChEBI] synonym: "neurotoxic agent" RELATED [ChEBI] synonym: "neurotoxic agents" RELATED [ChEBI] synonym: "neurotoxicant" RELATED [ChEBI] synonym: "neurotoxins" RELATED [ChEBI] xref: Wikipedia:Neurotoxin is_a: CHEBI:52209 ! aetiopathogenetic role is_a: CHEBI:64909 ! poison [Term] id: CHEBI:50994 name: primary amino compound namespace: chebi_ontology def: "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." [] subset: 3_STAR synonym: "primary amino compounds" RELATED [ChEBI] is_a: CHEBI:50047 ! organic amino compound relationship: is_conjugate_base_of CHEBI:65296 ! primary ammonium ion [Term] id: CHEBI:51086 name: chemical role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof within a chemical context." [] subset: 3_STAR is_a: BFO:0000023 ! role is_a: CHEBI:50906 ! role [Term] id: CHEBI:51143 name: nitrogen molecular entity namespace: chebi_ontology alt_id: CHEBI:25556 alt_id: CHEBI:7594 subset: 3_STAR synonym: "nitrogen compounds" RELATED [ChEBI] synonym: "nitrogen molecular entities" RELATED [ChEBI] synonym: "Nitrogenous compounds" RELATED [KEGG_COMPOUND] xref: KEGG:C06061 is_a: CHEBI:33302 ! pnictogen molecular entity relationship: has_part CHEBI:25555 ! nitrogen atom [Term] id: CHEBI:51151 name: dipolar compound namespace: chebi_ontology def: "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." [] subset: 3_STAR synonym: "dipolar compounds" RELATED [ChEBI] is_a: CHEBI:72695 ! organic molecule [Term] id: CHEBI:51422 name: organodiyl group namespace: chebi_ontology def: "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." [] subset: 3_STAR synonym: "organodiyl groups" RELATED [ChEBI] is_a: CHEBI:51446 ! organic divalent group [Term] id: CHEBI:51446 name: organic divalent group namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51447 name: organic univalent group namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:51958 name: organic polycyclic compound namespace: chebi_ontology subset: 3_STAR synonym: "organic polycyclic compounds" RELATED [ChEBI] is_a: CHEBI:33635 ! polycyclic compound is_a: CHEBI:33832 ! organic cyclic compound [Term] id: CHEBI:52206 name: biochemical role namespace: chebi_ontology def: "A biological role played by the molecular entity or part thereof within a biochemical context." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52209 name: aetiopathogenetic role namespace: chebi_ontology def: "A role played by the molecular entity or part thereof which causes the development of a pathological process." [] subset: 3_STAR synonym: "etiopathogenetic agent" RELATED [ChEBI] synonym: "etiopathogenetic role" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52210 name: pharmacological role namespace: chebi_ontology def: "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." [] subset: 3_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52211 name: physiological role namespace: chebi_ontology subset: 1_STAR is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:52217 name: pharmaceutical namespace: chebi_ontology alt_id: CHEBI:33293 alt_id: CHEBI:33294 def: "Any substance introduced into a living organism with therapeutic or diagnostic purpose." [] subset: 3_STAR synonym: "farmaco" RELATED [ChEBI] synonym: "medicament" RELATED [ChEBI] synonym: "pharmaceuticals" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:52254 name: apatite namespace: chebi_ontology def: "A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl." [] subset: 3_STAR synonym: "hydroxyapatite" RELATED [ChEBI] xref: HMDB:HMDB0033610 is_a: CHEBI:46723 ! phosphate mineral [Term] id: CHEBI:52255 name: hydroxylapatite namespace: chebi_ontology def: "A phosphate mineral with the formula Ca5(PO4)3(OH)." [] subset: 3_STAR is_a: CHEBI:52254 ! apatite property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "Ca5HO13P3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "502.312" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "501.67595" xsd:string [Term] id: CHEBI:52845 name: cyclic organic group namespace: chebi_ontology def: "An organic group that consists of a closed ring. It may be a substituent or a skeleton." [] subset: 3_STAR synonym: "cyclic organic groups" RELATED [ChEBI] is_a: CHEBI:33247 ! organic group [Term] id: CHEBI:53000 name: epitope namespace: chebi_ontology def: "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." [] subset: 3_STAR synonym: "antigenic determinant" RELATED [ChEBI] synonym: "epitope function" RELATED [ChEBI] synonym: "epitope role" RELATED [ChEBI] is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:53309 name: polyanionic macromolecule namespace: chebi_ontology def: "A polymer carrying multiple negative charges." [] subset: 3_STAR synonym: "polyanion" RELATED [ChEBI] synonym: "polyanions" RELATED [SUBMITTER] is_a: CHEBI:53368 ! ionic macromolecule [Term] id: CHEBI:53368 name: ionic macromolecule namespace: chebi_ontology def: "A macromolecule containing ionic groups." [] subset: 3_STAR synonym: "ionic polymer" RELATED [ChEBI] synonym: "polyionic macromolecule" RELATED [ChEBI] is_a: CHEBI:33839 ! macromolecule [Term] id: CHEBI:5391 name: glucagon namespace: chebi_ontology def: "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." [] subset: 3_STAR synonym: "Glucagon" EXACT [KEGG_COMPOUND] synonym: "glucagon" RELATED INN [ChemIDplus] synonym: "Glucagone" RELATED [ChemIDplus] synonym: "glucagonum" RELATED INN [ChemIDplus] synonym: "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr" RELATED [ChEBI] synonym: "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr" RELATED [ChemIDplus] synonym: "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT" RELATED [ChEBI] synonym: "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine" EXACT IUPAC_NAME [IUPAC] xref: CAS:16941-32-5 {source="ChemIDplus"} xref: CAS:9007-92-5 {source="KEGG COMPOUND"} xref: CAS:9007-92-5 {source="ChemIDplus"} xref: Drug_Central:2994 {source="DrugCentral"} xref: DrugBank:DB00040 xref: KEGG:C01501 xref: KEGG:D00116 xref: PMID:21940356 {source="Europe PMC"} xref: PMID:22014161 {source="Europe PMC"} xref: PMID:22154917 {source="Europe PMC"} xref: PMID:22166985 {source="Europe PMC"} xref: PMID:22167521 {source="Europe PMC"} xref: PMID:22214853 {source="Europe PMC"} xref: PMID:22227186 {source="Europe PMC"} xref: PMID:22286080 {source="Europe PMC"} xref: PMID:22294753 {source="Europe PMC"} xref: PMID:22318544 {source="Europe PMC"} xref: PMID:22334714 {source="Europe PMC"} xref: PMID:22399501 {source="Europe PMC"} xref: PMID:22438981 {source="Europe PMC"} xref: PMID:22454291 {source="Europe PMC"} xref: Reaxys:13191924 {source="Reaxys"} xref: Wikipedia:Glucagon is_a: CHEBI:25905 ! peptide hormone property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C153H225N43O49S" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "MASNOZXLGMXCHN-ZLPAWPGGSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "3482.74700" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "3480.61570" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O" xsd:string [Term] id: CHEBI:5686 name: heterocyclic compound namespace: chebi_ontology def: "A cyclic compound having as ring members atoms of at least two different elements." [] subset: 3_STAR synonym: "compuesto heterociclico" RELATED [IUPAC] synonym: "compuestos heterociclicos" RELATED [IUPAC] synonym: "heterocycle" RELATED [ChEBI] synonym: "Heterocyclic compound" EXACT [KEGG_COMPOUND] synonym: "heterocyclic compounds" RELATED [ChEBI] is_a: CHEBI:33595 ! cyclic compound [Term] id: CHEBI:57887 name: tryptaminium namespace: chebi_ontology def: "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." [] subset: 3_STAR synonym: "2-(1H-indol-3-yl)ethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "tryptamine" RELATED [UniProt] synonym: "tryptaminium cation" RELATED [ChEBI] synonym: "tryptaminium(1+)" RELATED [ChEBI] xref: Gmelin:533978 {source="Gmelin"} is_a: CHEBI:65296 ! primary ammonium ion relationship: has_role CHEBI:75771 ! mouse metabolite relationship: has_role CHEBI:76924 ! plant metabolite relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:16765 ! tryptamine property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C10H13N2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "APJYDQYYACXCRM-UHFFFAOYSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "161.22310" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "161.10732" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]CCc1c[nH]c2ccccc12" xsd:string [Term] id: CHEBI:57977 name: bilirubin(2-) namespace: chebi_ontology def: "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." [] subset: 3_STAR synonym: "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate" RELATED [ChEBI] synonym: "bilirubin dianion" RELATED [ChEBI] synonym: "bilirubin IXalpha" RELATED [UniProt] xref: Beilstein:4083310 {source="Beilstein"} is_a: CHEBI:28965 ! dicarboxylic acid dianion is_a: CHEBI:59252 ! linear tetrapyrrole anion relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_base_of CHEBI:16990 ! bilirubin IXalpha property_value: http://purl.obolibrary.org/obo/chebi/charge "-2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C33H34N4O6" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-L" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "582.64630" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "582.24893" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "CC1=C(C=C)\\C(NC1=O)=C\\c1[nH]c(Cc2[nH]c(\\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC([O-])=O)c(CCC([O-])=O)c1C" xsd:string [Term] id: CHEBI:58958 name: organosulfate oxoanion namespace: chebi_ontology def: "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." [] subset: 3_STAR synonym: "organosulfate oxoanions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion is_a: CHEBI:33482 ! sulfur oxoanion relationship: has_functional_parent CHEBI:16189 ! sulfate relationship: is_conjugate_base_of CHEBI:25704 ! organic sulfate property_value: http://purl.obolibrary.org/obo/chebi/charge "-1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "O4SR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "96.06300" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "95.95173" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[O-]S(=O)(=O)O[*]" xsd:string [Term] id: CHEBI:59252 name: linear tetrapyrrole anion namespace: chebi_ontology def: "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." [] subset: 3_STAR synonym: "acyclic tetrapyrrole anion" RELATED [ChEBI] synonym: "acyclic tetrapyrrole anions" RELATED [ChEBI] synonym: "linear tetrapyrrole anions" RELATED [ChEBI] is_a: CHEBI:25696 ! organic anion [Term] id: CHEBI:59698 name: phosphoric acids namespace: chebi_ontology def: "Compounds containing one or more phosphoric acid units." [] subset: 3_STAR is_a: CHEBI:33457 ! phosphorus oxoacid [Term] id: CHEBI:59740 name: nucleophilic reagent namespace: chebi_ontology def: "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." [] subset: 3_STAR synonym: "nucleophile" RELATED [ChEBI] synonym: "nucleophiles" RELATED [ChEBI] synonym: "nucleophilic reagents" RELATED [ChEBI] is_a: CHEBI:33893 ! reagent is_a: CHEBI:39144 ! Lewis base [Term] id: CHEBI:59999 name: chemical substance namespace: chebi_ontology def: "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." [] subset: 3_STAR synonym: "Chemische Substanz" RELATED [ChEBI] is_a: CHEBI:24431 ! chemical entity [Term] id: CHEBI:60004 name: mixture namespace: chebi_ontology def: "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." [] subset: 3_STAR synonym: "Mischung" RELATED [ChEBI] is_a: CHEBI:59999 ! chemical substance [Term] id: CHEBI:60027 name: polymer namespace: chebi_ontology def: "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." [] subset: 3_STAR synonym: "Kunststoff" RELATED [ChEBI] synonym: "Polymer" EXACT [ChEBI] xref: Wikipedia:Polymer is_a: CHEBI:60004 ! mixture relationship: has_part CHEBI:33839 ! macromolecule [Term] id: CHEBI:60164 name: ionic polymer namespace: chebi_ontology def: "An ionic polymer is a polymer, composed of ionic macromolecules." [] subset: 3_STAR synonym: "polyionic polymer" RELATED [ChEBI] is_a: CHEBI:60027 ! polymer relationship: has_part CHEBI:53368 ! ionic macromolecule [Term] id: CHEBI:60242 name: monovalent inorganic cation namespace: chebi_ontology def: "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." [] subset: 3_STAR synonym: "a monovalent cation" RELATED [UniProt] is_a: CHEBI:36915 ! inorganic cation [Term] id: CHEBI:60466 name: peptide zwitterion namespace: chebi_ontology def: "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." [] subset: 3_STAR synonym: "a peptide" RELATED [UniProt] synonym: "peptide zwitterions" RELATED [ChEBI] is_a: CHEBI:27369 ! zwitterion relationship: is_tautomer_of CHEBI:16670 ! peptide property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R(C2H2NOR)n" xsd:string [Term] id: CHEBI:61120 name: nucleobase-containing molecular entity namespace: chebi_ontology def: "Any compound that has a nucleobase as a part." [] subset: 3_STAR synonym: "nucleobase-containing compound" RELATED [SUBMITTER] synonym: "nucleobase-containing compounds" RELATED [ChEBI] synonym: "nucleobase-containing molecular entities" RELATED [ChEBI] is_a: CHEBI:33833 ! heteroarene is_a: CHEBI:51143 ! nitrogen molecular entity relationship: has_functional_parent CHEBI:18282 ! nucleobase [Term] id: CHEBI:61469 name: polyanionic polymer namespace: chebi_ontology def: "A polymer, composed of polyanion macromolecules." [] subset: 3_STAR synonym: "polyanion" RELATED [ChEBI] synonym: "polyanions" RELATED [ChEBI] is_a: CHEBI:60164 ! ionic polymer relationship: has_part CHEBI:53309 ! polyanionic macromolecule [Term] id: CHEBI:63248 name: oxidising agent namespace: chebi_ontology def: "A substance that removes electrons from another reactant in a redox reaction." [] subset: 3_STAR synonym: "oxidant" RELATED [ChEBI] synonym: "oxidants" RELATED [ChEBI] synonym: "oxidiser" RELATED [ChEBI] synonym: "oxidisers" RELATED [ChEBI] synonym: "oxidising agents" RELATED [ChEBI] synonym: "oxidizer" RELATED [ChEBI] synonym: "oxidizers" RELATED [ChEBI] synonym: "oxidizing agent" RELATED [ChEBI] synonym: "oxidizing agents" RELATED [ChEBI] is_a: CHEBI:51086 ! chemical role [Term] id: CHEBI:63299 name: carbohydrate derivative namespace: chebi_ontology def: "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." [] subset: 3_STAR synonym: "carbohydrate derivatives" RELATED [ChEBI] synonym: "derivatised carbohydrate" RELATED [ChEBI] synonym: "derivatised carbohydrates" RELATED [ChEBI] synonym: "derivatized carbohydrate" RELATED [ChEBI] synonym: "derivatized carbohydrates" RELATED [ChEBI] is_a: CHEBI:78616 ! carbohydrates and carbohydrate derivatives relationship: has_functional_parent CHEBI:16646 ! carbohydrate [Term] id: CHEBI:63436 name: carbohydrate acid derivative namespace: chebi_ontology def: "A carbohydrate derivative that is formally obtained from a carbohydrate acid." [] subset: 3_STAR synonym: "carbohydrate acid derivatives" RELATED [ChEBI] is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:33720 ! carbohydrate acid relationship: is_conjugate_acid_of CHEBI:63551 ! carbohydrate acid derivative anion [Term] id: CHEBI:63534 name: monoamine namespace: chebi_ontology def: "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." [] subset: 3_STAR synonym: "monoamines" RELATED [ChEBI] synonym: "naturally occurring monoamine" RELATED [ChEBI] synonym: "naturally occurring monoamines" RELATED [ChEBI] xref: PMID:21822758 {source="Europe PMC"} xref: PMID:21993877 {source="Europe PMC"} xref: PMID:22005599 {source="Europe PMC"} xref: PMID:22082101 {source="Europe PMC"} xref: PMID:22153577 {source="Europe PMC"} xref: PMID:22213370 {source="Europe PMC"} xref: PMID:22218931 {source="Europe PMC"} xref: PMID:22342987 {source="Europe PMC"} xref: PMID:22371656 {source="Europe PMC"} is_a: CHEBI:64365 ! aralkylamino compound [Term] id: CHEBI:63551 name: carbohydrate acid derivative anion namespace: chebi_ontology def: "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." [] subset: 3_STAR synonym: "carbohydrate acid anion derivative" RELATED [ChEBI] synonym: "carbohydrate acid anion derivatives" RELATED [ChEBI] synonym: "carbohydrate acid derivative anions" RELATED [ChEBI] is_a: CHEBI:29067 ! carboxylic acid anion relationship: has_functional_parent CHEBI:33721 ! carbohydrate acid anion relationship: is_conjugate_base_of CHEBI:63436 ! carbohydrate acid derivative [Term] id: CHEBI:64047 name: food additive namespace: chebi_ontology def: "Any substance which is added to food to preserve or enhance its flavour and/or appearance." [] subset: 3_STAR synonym: "food additives" RELATED [ChEBI] xref: Wikipedia:Food_additive is_a: CHEBI:33232 ! application is_a: CHEBI:78295 ! food component [Term] id: CHEBI:64049 name: food acidity regulator namespace: chebi_ontology def: "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." [] subset: 3_STAR synonym: "acidity regulator" RELATED [ChEBI] synonym: "acidity regulators" RELATED [ChEBI] synonym: "food acidity regulators" RELATED [ChEBI] synonym: "pH control agent" RELATED [ChEBI] synonym: "pH control agents" RELATED [ChEBI] xref: Wikipedia:Acidity_regulator is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:64365 name: aralkylamino compound namespace: chebi_ontology def: "An organic amino compound in which an aminoalkyl group is linked to an arene." [] subset: 3_STAR synonym: "aralkylamino compounds" RELATED [ChEBI] is_a: CHEBI:50047 ! organic amino compound [Term] id: CHEBI:64628 name: somatostatin namespace: chebi_ontology def: "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." [] subset: 3_STAR synonym: "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]" RELATED [ChEBI] synonym: "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide" EXACT IUPAC_NAME [IUPAC] synonym: "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide" RELATED [ChemIDplus] synonym: "somatostatin" RELATED INN [KEGG_DRUG] synonym: "Somatostatin-1" RELATED [KEGG_COMPOUND] synonym: "Somatostatin-14" RELATED [KEGG_COMPOUND] synonym: "somatostatina" RELATED INN [ChemIDplus] synonym: "somatostatine" RELATED INN [ChemIDplus] synonym: "somatostatinum" RELATED INN [ChemIDplus] synonym: "Synthetic growth hormone release-inhibiting hormone" RELATED [ChemIDplus] xref: CAS:38916-34-6 {source="KEGG DRUG"} xref: CAS:38916-34-6 {source="ChemIDplus"} xref: Drug_Central:2997 {source="DrugCentral"} xref: HMDB:HMDB0013072 xref: KEGG:C16022 xref: KEGG:D07431 xref: LINCS:LSM-5326 xref: PMID:21922516 {source="Europe PMC"} xref: PMID:22129035 {source="Europe PMC"} xref: PMID:22147011 {source="Europe PMC"} xref: PMID:22251942 {source="Europe PMC"} xref: PMID:22483686 {source="Europe PMC"} xref: PMID:22509294 {source="Europe PMC"} xref: Reaxys:10148626 {source="Reaxys"} xref: Wikipedia:Somatostatin is_a: CHEBI:24533 ! heterodetic cyclic peptide is_a: CHEBI:25905 ! peptide hormone property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C76H104N18O19S2" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "NHXLMOGPVYXJNR-ATOGVRKGSA-N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "1637.87800" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "1636.71666" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N" xsd:string [Term] id: CHEBI:64708 name: one-carbon compound namespace: chebi_ontology def: "An organic molecular entity containing a single carbon atom (C1)." [] subset: 3_STAR synonym: "one-carbon compounds" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64709 name: organic acid namespace: chebi_ontology def: "Any organic molecular entity that is acidic and contains carbon in covalent linkage." [] subset: 3_STAR synonym: "organic acids" RELATED [ChEBI] is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:64909 name: poison namespace: chebi_ontology def: "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." [] subset: 3_STAR synonym: "poisonous agent" RELATED [ChEBI] synonym: "poisonous agents" RELATED [ChEBI] synonym: "poisonous substance" RELATED [ChEBI] synonym: "poisonous substances" RELATED [ChEBI] synonym: "poisons" RELATED [ChEBI] synonym: "toxic agent" RELATED [ChEBI] synonym: "toxic agents" RELATED [ChEBI] synonym: "toxic substance" RELATED [ChEBI] synonym: "toxic substances" RELATED [ChEBI] xref: Wikipedia:Poison is_a: CHEBI:24432 ! biological role [Term] id: CHEBI:65212 name: polysaccharide derivative namespace: chebi_ontology def: "A carbohydrate derivative that is any derivative of a polysaccharide." [] subset: 3_STAR synonym: "polysaccharide derivatives" RELATED [ChEBI] is_a: CHEBI:167559 ! glycan is_a: CHEBI:33694 ! biomacromolecule is_a: CHEBI:63299 ! carbohydrate derivative relationship: has_functional_parent CHEBI:18154 ! polysaccharide [Term] id: CHEBI:65255 name: food preservative namespace: chebi_ontology def: "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." [] subset: 3_STAR synonym: "food preservatives" RELATED [ChEBI] is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:65256 name: antimicrobial food preservative namespace: chebi_ontology def: "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." [] subset: 3_STAR synonym: "antimicrobial food preservatives" RELATED [ChEBI] synonym: "antimicrobial preservative" RELATED [ChEBI] synonym: "antimicrobial preservatives" RELATED [ChEBI] is_a: CHEBI:33281 ! antimicrobial agent is_a: CHEBI:65255 ! food preservative [Term] id: CHEBI:65296 name: primary ammonium ion namespace: chebi_ontology def: "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." [] subset: 3_STAR synonym: "a primary amine" RELATED [UniProt] synonym: "substituted ammonium" RELATED [ChEBI] is_a: CHEBI:25697 ! organic cation is_a: CHEBI:35274 ! ammonium ion derivative relationship: is_conjugate_acid_of CHEBI:50994 ! primary amino compound property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "H3NR" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "17.031" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "17.02655" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+][*]" xsd:string [Term] id: CHEBI:67079 name: anti-inflammatory agent namespace: chebi_ontology def: "Any compound that has anti-inflammatory effects." [] subset: 3_STAR synonym: "anti-inflammatory agents" RELATED [ChEBI] synonym: "antiinflammatory agent" RELATED [ChEBI] synonym: "antiinflammatory agents" RELATED [ChEBI] is_a: CHEBI:33232 ! application [Term] id: CHEBI:72587 name: (R)-noradrenaline(1+) namespace: chebi_ontology def: "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." [] subset: 3_STAR synonym: "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium" EXACT IUPAC_NAME [IUPAC] synonym: "(R)-noradrenaline" RELATED [UniProt] synonym: "(R)-noradrenaline cation" RELATED [ChEBI] synonym: "(R)-noradrenalinium cation" RELATED [ChEBI] synonym: "(R)-noradrenalinium(1+)" RELATED [ChEBI] xref: PDBeChem:E5E is_a: CHEBI:166902 ! noradrenaline(1+) relationship: has_role CHEBI:77746 ! human metabolite relationship: is_conjugate_acid_of CHEBI:18357 ! (R)-noradrenaline property_value: http://purl.obolibrary.org/obo/chebi/charge "+1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8H12NO3" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-O" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "170.187" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "170.08117" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O" xsd:string [Term] id: CHEBI:72695 name: organic molecule namespace: chebi_ontology def: "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." [] subset: 3_STAR synonym: "organic compound" RELATED [ChEBI] synonym: "organic compounds" RELATED [ChEBI] synonym: "organic molecules" RELATED [ChEBI] is_a: CHEBI:25367 ! molecule is_a: CHEBI:50860 ! organic molecular entity [Term] id: CHEBI:72813 name: exopolysaccharide namespace: chebi_ontology def: "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." [] subset: 3_STAR synonym: "exopolysaccharides" RELATED [ChEBI] synonym: "extracellular polymeric substance" RELATED [ChEBI] synonym: "extracellular polymeric substances" RELATED [ChEBI] xref: MetaCyc:Exopolysaccharides xref: PMID:11160795 {source="Europe PMC"} xref: PMID:11785425 {source="Europe PMC"} xref: PMID:1444258 {source="Europe PMC"} xref: PMID:15738217 {source="Europe PMC"} xref: PMID:16075348 {source="Europe PMC"} xref: PMID:17440912 {source="Europe PMC"} xref: PMID:18097339 {source="Europe PMC"} xref: PMID:19453747 {source="Europe PMC"} xref: PMID:20172021 {source="Europe PMC"} xref: PMID:20631870 {source="Europe PMC"} xref: PMID:20718297 {source="Europe PMC"} xref: PMID:2688547 {source="Europe PMC"} xref: PMID:6354590 {source="Europe PMC"} xref: Wikipedia:Exopolysaccharide xref: Wikipedia:Extracellular_polymeric_substance is_a: CHEBI:33694 ! biomacromolecule [Term] id: CHEBI:73398 name: indole skeleton namespace: chebi_ontology def: "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." [] subset: 3_STAR is_a: CHEBI:73541 ! organic heterobicyclic ring property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C8N" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "110.09230" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "110.00307" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*" xsd:string [Term] id: CHEBI:73541 name: organic heterobicyclic ring namespace: chebi_ontology def: "A bicyclic organic group that contains both carbon and hetero atoms." [] subset: 3_STAR synonym: "organic heterobicyclic rings" RELATED [ChEBI] is_a: CHEBI:52845 ! cyclic organic group [Term] id: CHEBI:75763 name: eukaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." [] subset: 3_STAR synonym: "eukaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:75767 name: animal metabolite namespace: chebi_ontology alt_id: CHEBI:77721 alt_id: CHEBI:77743 def: "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." [] subset: 3_STAR synonym: "animal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:75768 name: mammalian metabolite namespace: chebi_ontology alt_id: CHEBI:77464 alt_id: CHEBI:77744 def: "Any animal metabolite produced during a metabolic reaction in mammals." [] subset: 3_STAR synonym: "mammalian metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:75771 name: mouse metabolite namespace: chebi_ontology def: "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." [] subset: 3_STAR synonym: "mouse metabolites" RELATED [ChEBI] synonym: "Mus musculus metabolite" RELATED [ChEBI] synonym: "Mus musculus metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:75772 name: Saccharomyces cerevisiae metabolite namespace: chebi_ontology alt_id: CHEBI:76949 alt_id: CHEBI:76951 def: "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." [] subset: 3_STAR synonym: "baker's yeast metabolite" RELATED [ChEBI] synonym: "baker's yeast metabolites" RELATED [ChEBI] synonym: "baker's yeast secondary metabolite" RELATED [ChEBI] synonym: "baker's yeast secondary metabolites" RELATED [ChEBI] synonym: "S. cerevisiae metabolite" RELATED [ChEBI] synonym: "S. cerevisiae metabolites" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolite" RELATED [ChEBI] synonym: "S. cerevisiae secondary metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae metabolites" RELATED [ChEBI] synonym: "Saccharomyces cerevisiae secondary metabolites" RELATED [ChEBI] is_a: CHEBI:76946 ! fungal metabolite [Term] id: CHEBI:75787 name: prokaryotic metabolite namespace: chebi_ontology def: "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." [] subset: 3_STAR synonym: "prokaryotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76206 name: xenobiotic metabolite namespace: chebi_ontology def: "Any metabolite produced by metabolism of a xenobiotic compound." [] subset: 3_STAR synonym: "xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:76759 name: EC 3.* (hydrolase) inhibitor namespace: chebi_ontology def: "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." [] subset: 3_STAR synonym: "EC 3.* (hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.* inhibitor" RELATED [ChEBI] synonym: "EC 3.* inhibitors" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitor" RELATED [ChEBI] synonym: "EC 3.*.*.* inhibitors" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitor" RELATED [ChEBI] synonym: "hydrolase (EC 3.*) inhibitors" RELATED [ChEBI] synonym: "hydrolase inhibitor" RELATED [ChEBI] synonym: "hydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Hydrolase is_a: CHEBI:23924 ! enzyme inhibitor [Term] id: CHEBI:76764 name: EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor namespace: chebi_ontology def: "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." [] subset: 3_STAR synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.* inhibitors" RELATED [ChEBI] is_a: CHEBI:76759 ! EC 3.* (hydrolase) inhibitor [Term] id: CHEBI:76807 name: EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor namespace: chebi_ontology def: "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." [] subset: 3_STAR synonym: "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.* inhibitors" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor" RELATED [ChEBI] synonym: "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" RELATED [ChEBI] is_a: CHEBI:76764 ! EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor [Term] id: CHEBI:76924 name: plant metabolite namespace: chebi_ontology alt_id: CHEBI:75766 alt_id: CHEBI:76925 def: "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." [] subset: 3_STAR synonym: "plant metabolites" RELATED [ChEBI] synonym: "plant secondary metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76946 name: fungal metabolite namespace: chebi_ontology alt_id: CHEBI:75765 alt_id: CHEBI:76947 def: "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." [] subset: 3_STAR synonym: "fungal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CHEBI:76967 name: human xenobiotic metabolite namespace: chebi_ontology def: "Any human metabolite produced by metabolism of a xenobiotic compound in humans." [] subset: 3_STAR synonym: "human xenobiotic metabolites" RELATED [ChEBI] is_a: CHEBI:76206 ! xenobiotic metabolite is_a: CHEBI:77746 ! human metabolite [Term] id: CHEBI:76969 name: bacterial metabolite namespace: chebi_ontology alt_id: CHEBI:75760 alt_id: CHEBI:76970 def: "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." [] subset: 3_STAR is_a: CHEBI:75787 ! prokaryotic metabolite [Term] id: CHEBI:76971 name: Escherichia coli metabolite namespace: chebi_ontology def: "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." [] subset: 3_STAR synonym: "E.coli metabolite" RELATED [ChEBI] synonym: "E.coli metabolites" RELATED [ChEBI] synonym: "Escherichia coli metabolites" RELATED [ChEBI] is_a: CHEBI:76969 ! bacterial metabolite [Term] id: CHEBI:77746 name: human metabolite namespace: chebi_ontology alt_id: CHEBI:75770 alt_id: CHEBI:77123 def: "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." [] subset: 3_STAR synonym: "H. sapiens metabolite" RELATED [ChEBI] synonym: "H. sapiens metabolites" RELATED [ChEBI] synonym: "Homo sapiens metabolite" RELATED [ChEBI] synonym: "Homo sapiens metabolites" RELATED [ChEBI] is_a: CHEBI:75768 ! mammalian metabolite [Term] id: CHEBI:77941 name: EC 3.5.1.4 (amidase) inhibitor namespace: chebi_ontology def: "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." [] subset: 3_STAR synonym: "acylamidase inhibitor" RELATED [ChEBI] synonym: "acylamidase inhibitors" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitor" RELATED [ChEBI] synonym: "acylamide amidohydrolase inhibitors" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitor" RELATED [ChEBI] synonym: "amidase (EC 3.5.1.4) inhibitors" RELATED [ChEBI] synonym: "amidase inhibitor" RELATED [ChEBI] synonym: "amidase inhibitors" RELATED [ChEBI] synonym: "amidohydrolase inhibitor" RELATED [ChEBI] synonym: "amidohydrolase inhibitors" RELATED [ChEBI] synonym: "deaminase inhibitor" RELATED [ChEBI] synonym: "deaminase inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 (amidase) inhibitors" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitor" RELATED [ChEBI] synonym: "EC 3.5.1.4 inhibitors" RELATED [ChEBI] synonym: "fatty acylamidase inhibitor" RELATED [ChEBI] synonym: "fatty acylamidase inhibitors" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitor" RELATED [ChEBI] synonym: "N-acetylaminohydrolase inhibitors" RELATED [ChEBI] xref: Wikipedia:Amidase is_a: CHEBI:76807 ! EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor [Term] id: CHEBI:77974 name: food packaging gas namespace: chebi_ontology def: "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." [] subset: 3_STAR synonym: "food packaging gases" RELATED [ChEBI] xref: Wikipedia:Packaging_gas is_a: CHEBI:64047 ! food additive [Term] id: CHEBI:78295 name: food component namespace: chebi_ontology def: "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." [] subset: 3_STAR synonym: "dietary component" RELATED [ChEBI] synonym: "dietary components" RELATED [ChEBI] synonym: "food components" RELATED [ChEBI] is_a: CHEBI:52211 ! physiological role [Term] id: CHEBI:78433 name: refrigerant namespace: chebi_ontology def: "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." [] subset: 3_STAR synonym: "refrigerants" RELATED [ChEBI] xref: Wikipedia:Refrigerant is_a: CHEBI:33232 ! application [Term] id: CHEBI:78608 name: alpha-amino acid zwitterion namespace: chebi_ontology alt_id: CHEBI:83409 def: "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." [] subset: 3_STAR synonym: "an alpha-amino acid" RELATED [UniProt] xref: MetaCyc:Alpha-Amino-Acids {source="SUBMITTER"} is_a: CHEBI:35238 ! amino acid zwitterion relationship: is_tautomer_of CHEBI:33704 ! alpha-amino acid property_value: http://purl.obolibrary.org/obo/chebi/charge "0" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/formula "C2H4NO2R" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/mass "74.059" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/monoisotopicmass "74.02420" xsd:string property_value: http://purl.obolibrary.org/obo/chebi/smiles "[NH3+]C([*])C([O-])=O" xsd:string [Term] id: CHEBI:78616 name: carbohydrates and carbohydrate derivatives namespace: chebi_ontology def: "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." [] subset: 3_STAR synonym: "carbohydrates and derivatives" RELATED [ChEBI] synonym: "carbohydrates and their derivatives" RELATED [ChEBI] is_a: CHEBI:36963 ! organooxygen compound [Term] id: CHEBI:78675 name: fundamental metabolite namespace: chebi_ontology def: "Any metabolite produced by all living cells." [] subset: 3_STAR synonym: "essential metabolite" RELATED [ChEBI] synonym: "essential metabolites" RELATED [ChEBI] synonym: "fundamental metabolites" RELATED [ChEBI] is_a: CHEBI:25212 ! metabolite [Term] id: CHEBI:79387 name: trivalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of three." [] subset: 3_STAR synonym: "trivalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79388 name: divalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of two." [] subset: 3_STAR synonym: "divalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:79389 name: monovalent inorganic anion namespace: chebi_ontology def: "Any inorganic anion with a valency of one." [] subset: 3_STAR synonym: "monovalent inorganic anions" RELATED [ChEBI] is_a: CHEBI:24834 ! inorganic anion [Term] id: CHEBI:83039 name: crustacean metabolite namespace: chebi_ontology def: "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." [] subset: 3_STAR synonym: "crustacean metabolites" RELATED [ChEBI] is_a: CHEBI:75767 ! animal metabolite [Term] id: CHEBI:83056 name: Daphnia magna metabolite namespace: chebi_ontology def: "A Daphnia metabolite produced by the species Daphnia magna." [] subset: 3_STAR synonym: "Daphnia magna metabolites" RELATED [ChEBI] is_a: CHEBI:83057 ! Daphnia metabolite [Term] id: CHEBI:83057 name: Daphnia metabolite namespace: chebi_ontology def: "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" [] subset: 3_STAR synonym: "Daphnia metabolites" RELATED [ChEBI] xref: Wikipedia:Daphnia is_a: CHEBI:83039 ! crustacean metabolite [Term] id: CHEBI:84729 name: hydroxyindoles namespace: chebi_ontology def: "Any member of the class of indoles carrying at least one hydroxy group." [] subset: 3_STAR is_a: CHEBI:24828 ! indoles is_a: CHEBI:33822 ! organic hydroxy compound [Term] id: CHEBI:84735 name: algal metabolite namespace: chebi_ontology def: "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." [] subset: 3_STAR synonym: "algal metabolites" RELATED [ChEBI] is_a: CHEBI:75763 ! eukaryotic metabolite [Term] id: CL:0000000 name: cell def: "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." [CARO:mah] comment: The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one). subset: ubprop:upper_level xref: CALOHA:TS-2035 xref: FBbt:00007002 xref: FMA:68646 xref: GO:0005623 xref: KUPO:0000002 xref: MESH:D002477 xref: VHOG:0001533 xref: WBbt:0004017 xref: XAO:0003012 is_a: UBERON:0000061 ! anatomical structure disjoint_from: GO:0031012 ! extracellular matrix disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle relationship: has_part GO:0005634 {gci_filler="PATO:0001407", gci_relation="has_characteristic"} ! nucleus relationship: has_part GO:0005634 {gci_filler="PATO:0001908", gci_relation="has_characteristic"} ! nucleus relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: CL:0000003 name: native cell def: "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment)." [CARO:mah] comment: To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12). subset: ubprop:upper_level synonym: "cell in vivo" NARROW [] xref: CARO:0000013 is_a: CL:0000000 ! cell [Term] id: CL:0000005 name: fibroblast neural crest derived def: "Any fibroblast that is deriived from the neural crest." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000057 ! fibroblast is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000006 name: neuronal receptor cell synonym: "neuronal receptor cell (sensu Animalia)" EXACT [] is_a: CL:0000101 ! sensory neuron is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000007 name: early embryonic cell (metazoa) def: "A cell found in the embryo before the formation of all the gem layers is complete." [GOC:tfm] is_a: CL:0002321 ! embryonic cell (metazoa) [Term] id: CL:0000008 name: migratory cranial neural crest cell def: "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007091] is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000011 name: migratory trunk neural crest cell def: "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination." [https://orcid.org/0000-0001-5208-3432, ZFA:0007095] is_a: CL:0000333 ! migratory neural crest cell [Term] id: CL:0000014 name: germ line stem cell def: "A stem cell that is the precursor of gametes." [doi:10.1016/j.stem.2012.05.016] synonym: "germline stem cell" EXACT [] xref: FBbt:00004861 is_a: CL:0000034 {is_inferred="true"} ! stem cell is_a: CL:0000039 {is_inferred="true"} ! germ line cell intersection_of: CL:0000039 ! germ line cell intersection_of: capable_of GO:0017145 ! stem cell division [Term] id: CL:0000015 name: male germ cell def: "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis." [https://orcid.org/0000-0001-5208-3432, PMID:29462262] xref: FMA:72290 xref: MA:0002765 xref: ncithesaurus:Spermatogenic_Cell xref: VHOG:0001531 is_a: CL:0000586 {is_inferred="true"} ! germ cell relationship: capable_of_part_of GO:0007283 ! spermatogenesis property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/574" xsd:string [Term] id: CL:0000017 name: spermatocyte def: "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids." [GOC:tfm, MESH:D013090] xref: BTO:0001275 xref: CALOHA:TS-0951 xref: EMAPA:31484 xref: FBbt:00004936 xref: FMA:84049 xref: WBbt:0006799 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000015 {is_inferred="true"} ! male germ cell is_a: CL:0000548 ! animal cell intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0048137 ! spermatocyte division relationship: capable_of GO:0048137 ! spermatocyte division relationship: develops_from CL:0000020 ! spermatogonium [Term] id: CL:0000018 name: spermatid def: "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa." [MESH:D013087] synonym: "nematoblast" EXACT [] xref: BTO:0001274 xref: CALOHA:TS-0950 xref: EMAPA:31486 xref: FBbt:00004942 xref: FMA:72294 xref: WBbt:0006800 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000015 {is_inferred="true"} ! male germ cell is_a: CL:0000413 ! haploid cell is_a: CL:0000548 ! animal cell intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0001675 ! acrosome assembly intersection_of: capable_of GO:0007288 ! sperm axoneme assembly intersection_of: capable_of GO:0007289 ! spermatid nucleus differentiation intersection_of: has_characteristic PATO:0001375 ! haploid relationship: capable_of GO:0001675 ! acrosome assembly relationship: capable_of GO:0007288 ! sperm axoneme assembly relationship: capable_of GO:0007289 ! spermatid nucleus differentiation relationship: develops_from CL:0000657 ! secondary spermatocyte [Term] id: CL:0000019 name: sperm def: "A mature male germ cell that develops from a spermatid." [GOC:tfm, MESH:D013094] synonym: "sperm cell" EXACT [] synonym: "spermatozoid" EXACT [] synonym: "spermatozoon" EXACT [] xref: BTO:0001277 xref: BTO:0002046 xref: CALOHA:TS-0949 xref: FBbt:00004954 xref: FMA:67338 xref: WBbt:0006798 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000408 {is_inferred="true"} ! male gamete relationship: develops_from CL:0000018 ! spermatid [Term] id: CL:0000020 name: spermatogonium def: "An euploid male germ cell of an early stage of spermatogenesis." [MESH:D013093] synonym: "spermatogonial cell" EXACT [] xref: BTO:0000958 xref: CALOHA:TS-2193 xref: EMAPA:31482 xref: FBbt:00004934 xref: FBbt:00004935 xref: FMA:72291 is_a: CL:0000015 ! male germ cell is_a: CL:0000548 ! animal cell intersection_of: CL:0000015 ! male germ cell intersection_of: has_characteristic PATO:0001394 ! diploid intersection_of: has_characteristic PATO:0001501 ! immature relationship: has_characteristic PATO:0001394 ! diploid relationship: has_characteristic PATO:0001501 ! immature [Term] id: CL:0000021 name: female germ cell def: "Female germ cell is a germ cell that supports female gamete production." [GOC:tfm, PMID:11023867, PMID:20454446] xref: MA:0000388 xref: ncithesaurus:Egg xref: VHOG:0001530 is_a: CL:0000586 {is_inferred="true"} ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: capable_of GO:0048477 ! oogenesis relationship: capable_of GO:0048477 ! oogenesis [Term] id: CL:0000022 name: female germ line stem cell def: "A stem cell that is the precursor of female gametes." [doi:10.1016/j.stem.2012.05.016] xref: FBbt:00004873 is_a: CL:0000014 {is_inferred="true"} ! germ line stem cell is_a: CL:0000021 {is_inferred="true"} ! female germ cell intersection_of: CL:0000021 ! female germ cell intersection_of: capable_of GO:0017145 ! stem cell division [Term] id: CL:0000023 name: oocyte def: "A female germ cell that has entered meiosis." [GOC:tfm, ISBN:0721662544] synonym: "oogonium" RELATED [] xref: BTO:0000964 xref: CALOHA:TS-0711 xref: FBbt:00004886 xref: FMA:18644 xref: MESH:D009865 xref: WBbt:0006797 is_a: CL:0000021 {is_inferred="true"} ! female germ cell is_a: CL:0000548 ! animal cell relationship: participates_in GO:0007143 ! female meiotic nuclear division [Term] id: CL:0000024 name: oogonial cell def: "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." [GOC:tfm, ISBN:0721662544] xref: FMA:83673 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000021 {is_inferred="true"} ! female germ cell is_a: CL:0000548 ! animal cell intersection_of: CL:0000021 ! female germ cell intersection_of: capable_of GO:0000278 ! mitotic cell cycle relationship: capable_of GO:0000278 ! mitotic cell cycle relationship: develops_from CL:0000670 ! primordial germ cell [Term] id: CL:0000025 name: egg cell def: "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." [GOC:tfm, ISBN:0721662544] synonym: "mature oocyte" EXACT [] synonym: "ovum" EXACT [] xref: BTO:0000369 xref: BTO:0003801 xref: CALOHA:TS-2191 xref: FBbt:00057012 xref: FMA:67343 xref: MA:0000388 xref: MESH:D010063 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000548 ! animal cell is_a: CL:0000675 {is_inferred="true"} ! female gamete relationship: develops_from CL:0000023 ! oocyte relationship: participates_in GO:0007143 ! female meiotic nuclear division [Term] id: CL:0000027 name: smooth muscle cell neural crest derived def: "A smooth muscle cell derived from the neural crest." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0000008 ! migratory cranial neural crest cell [Term] id: CL:0000029 name: neural crest derived neuron synonym: "neuron neural crest derived" EXACT [] is_a: CL:0000540 {is_inferred="true"} ! neuron is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000540 ! neuron intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: develops_from CL:0002676 ! neural crest derived neuroblast [Term] id: CL:0000030 name: glioblast is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000548 ! animal cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000031 name: neuroblast (sensu Vertebrata) def: "A cell that will develop into a neuron often after a migration phase." [GOC:NV, http://en.wikipedia.org/wiki/Neuroblast] synonym: "neuroblast" EXACT [] xref: BTO:0000930 xref: FMA:70563 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000548 ! animal cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: CL:0000034 name: stem cell def: "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:tfm, MESH:D013234] comment: This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’. subset: human_reference_atlas synonym: "animal stem cell" EXACT [] xref: CALOHA:TS-2086 xref: FMA:63368 is_a: CL:0000548 ! animal cell is_a: CL:0011115 ! precursor cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0017145 ! stem cell division relationship: capable_of GO:0017145 ! stem cell division relationship: in_taxon NCBITaxon:33208 ! Metazoa property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000035 name: single fate stem cell def: "A stem cell that self-renews as well as give rise to a single mature cell type." [GOC:tfm] synonym: "unipotent stem cell" EXACT [] synonym: "unipotential stem cell" EXACT [] xref: FMA:70569 is_a: CL:0000723 ! somatic stem cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0017145 ! stem cell division intersection_of: has_characteristic PATO:0001400 ! unipotent relationship: has_characteristic PATO:0001400 ! unipotent [Term] id: CL:0000037 name: hematopoietic stem cell def: "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Hematopoietic_stem_cell, PMID:19022770] comment: Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative. subset: blood_and_immune_upper_slim subset: human_reference_atlas synonym: "blood forming stem cell" EXACT [] synonym: "colony forming unit hematopoietic" RELATED [] synonym: "hemopoietic stem cell" EXACT [] synonym: "HSC" EXACT [] xref: BTO:0000725 xref: CALOHA:TS-0448 xref: FMA:70337 xref: FMA:86475 xref: MESH:D006412 xref: VHOG:0001485 is_a: CL:0000723 ! somatic stem cell is_a: CL:0008001 ! hematopoietic precursor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: capable_of GO:0048103 ! somatic stem cell division intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0002244 ! hematopoietic progenitor cell differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000566 ! angioblastic mesenchymal cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000038 name: erythroid progenitor cell def: "A progenitor cell committed to the erythroid lineage." [GOC:add, ISBN:0721601464] subset: blood_and_immune_upper_slim synonym: "BFU-E" RELATED [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] synonym: "CFU-E" RELATED [] synonym: "colony forming unit erythroid" RELATED [] synonym: "erythroid stem cell" RELATED [] xref: BTO:0004911 is_a: CL:0000764 ! erythroid lineage cell is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell [Term] id: CL:0000039 name: germ line cell def: "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." [GOC:tfm, ISBN:0721662544] comment: Originally this term had some plant germ line cell children. subset: ubprop:upper_level is_a: CL:0000003 ! native cell disjoint_from: CL:0002371 ! somatic cell relationship: capable_of GO:0022414 ! reproductive process [Term] id: CL:0000048 name: multi fate stem cell def: "A stem cell that can give rise to multiple lineages of cells." [GOC:add] synonym: "multi-fate stem cell" EXACT [] synonym: "multifate stem cell" EXACT [] synonym: "multipotent cell" EXACT [] synonym: "multipotent stem cell" EXACT [] xref: FMA:84789 is_a: CL:0000034 ! stem cell is_a: CL:0002371 ! somatic cell intersection_of: CL:0002371 ! somatic cell intersection_of: capable_of GO:0017145 ! stem cell division intersection_of: has_characteristic PATO:0001402 ! multipotent relationship: has_characteristic PATO:0001402 ! multipotent [Term] id: CL:0000049 name: common myeloid progenitor def: "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." [GOC:add, ISBN:0878932437, MESH:D023461] comment: This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059). subset: human_reference_atlas synonym: "CFU-GEMM" RELATED [ISBN:0878932437] synonym: "CFU-S" RELATED [ISBN:0878932437] synonym: "CMP" EXACT [ISBN:0878932437] synonym: "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte" RELATED [ISBN:0878932437] synonym: "common myeloid precursor" EXACT [] synonym: "multipotential myeloid stem cell" RELATED [ISBN:0878932437] synonym: "myeloid stem cell" RELATED [ISBN:0878932437] synonym: "pluripotent stem cell (bone marrow)" RELATED [ISBN:0878932437] xref: BTO:0004730 is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell disjoint_from: CL:0000050 ! megakaryocyte-erythroid progenitor cell disjoint_from: CL:0000051 ! common lymphoid progenitor property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000050 name: megakaryocyte-erythroid progenitor cell def: "A progenitor cell committed to the megakaryocyte and erythroid lineages." [GOC:add, GOC:dsd, GOC:tfm, http://en.wikipedia.org/wiki/Megakaryocyte-erythroid_progenitor_cell, MESH:D055015, PMID:16647566] comment: MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2. subset: human_reference_atlas synonym: "CFU-EM" EXACT [] synonym: "CFU-MegE" EXACT [] synonym: "colony forming unit erythroid megakaryocyte" EXACT [] synonym: "Meg/E progenitor" EXACT [] synonym: "megakaryocyte/erythrocyte progenitor" EXACT [] synonym: "megakaryocyte/erythroid progenitor cell" EXACT [] synonym: "MEP" EXACT [] is_a: CL:0000763 ! myeloid cell is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: capable_of GO:0030219 ! megakaryocyte differentiation property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000051 name: common lymphoid progenitor def: "A oligopotent progenitor cell committed to the lymphoid lineage." [GOC:add, GOC:dsd, GOC:tfm, PMID:10407577, PMID:16551251] comment: CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative. subset: human_reference_atlas synonym: "CLP" EXACT [] synonym: "committed lymphopoietic stem cell" RELATED [] synonym: "common lymphocyte precursor" EXACT [] synonym: "common lymphocyte progenitor" EXACT [] synonym: "common lymphoid precursor" EXACT [] synonym: "early lymphocyte progenitor" RELATED [] synonym: "ELP" RELATED [] synonym: "lymphoid stem cell" RELATED [] synonym: "lymphopoietic stem cell" RELATED [] is_a: CL:0002032 {is_inferred="true"} ! hematopoietic oligopotent progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: capable_of GO:0030098 ! lymphocyte differentiation relationship: capable_of GO:0030098 ! lymphocyte differentiation property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000052 name: totipotent stem cell def: "A stem cell from which all cells of the body can form." [GOC:add, GOC:tfm] synonym: "totipotential stem cell" EXACT [] xref: FMA:84790 xref: MESH:D039901 is_a: CL:0000723 ! somatic stem cell [Term] id: CL:0000055 name: non-terminally differentiated cell def: "A precursor cell with a limited number of potential fates." [SANBI:mhl] comment: define using PATO mulit-potent or oligopotent? synonym: "blast cell" EXACT [] xref: BTO:0000125 xref: FMA:84782 is_a: CL:0011115 ! precursor cell [Term] id: CL:0000056 name: myoblast def: "A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair." [GOC:tfm, MESH:D032446, PMID:21849021] xref: BTO:0000222 xref: CALOHA:TS-0650 xref: FBbt:00005083 xref: FMA:70335 xref: VHOG:0001529 is_a: CL:0000680 ! muscle precursor cell [Term] id: CL:0000057 name: fibroblast def: "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." [http://en.wikipedia.org/wiki/Fibroblast, ISBN:0517223651, MESH:D005347] comment: These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative. subset: human_reference_atlas xref: BTO:0000452 xref: CALOHA:TS-0362 xref: FMA:63877 xref: VHOG:0001482 is_a: CARO:0000000 ! anatomical entity is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000058 name: chondroblast def: "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell." [GO_REF:0000034, GOC:tfm, ISBN:0618947256] synonym: "chrondoplast" EXACT [] xref: BTO:0003607 xref: FMA:66783 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0007009 ! prechondroblast relationship: produces UBERON:0002418 ! cartilage tissue [Term] id: CL:0000059 name: ameloblast def: "Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell." [GO_REF:0000034, GOC:tfm, MESH:D000565] comment: non-encoded relationship from VSAO produces VSAO:0000066 synonym: "amelocyte" EXACT [] synonym: "enamel secreting cell" EXACT [] xref: BTO:0001663 xref: FMA:70576 is_a: CL:0000146 ! simple columnar epithelial cell is_a: CL:0000151 ! secretory cell is_a: CL:0002077 ! ecto-epithelial cell relationship: adjacent_to UBERON:0001763 ! odontogenic papilla relationship: capable_of GO:0097186 ! amelogenesis relationship: develops_from CL:0007000 ! preameloblast relationship: part_of UBERON:0005176 ! tooth enamel organ relationship: produces UBERON:0001752 ! enamel [Term] id: CL:0000060 name: odontoblast def: "Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell." [GO_REF:0000034, ISBN:0618947256] comment: legacy def: One of the cells forming the outer surface of dental pulp that produces tooth dentin. xref: BTO:0001769 xref: CALOHA:TS-0696 xref: FMA:62999 xref: MESH:D009804 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000710 ! neurecto-epithelial cell is_a: CL:0002148 ! dental pulp cell is_a: CL:0011026 ! progenitor cell relationship: develops_from CL:0007003 ! preodontoblast relationship: part_of UBERON:0005176 ! tooth enamel organ relationship: produces UBERON:0001751 ! dentine [Term] id: CL:0000064 name: ciliated cell def: "A cell that has a filiform extrusion of the cell surface." [GOC:tfm] xref: VHOG:0001532 xref: XAO:0000031 is_a: CL:0000003 ! native cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000003 ! native cell intersection_of: has_part GO:0005929 ! cilium relationship: has_part GO:0005929 ! cilium [Term] id: CL:0000066 name: epithelial cell def: "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." [FB:ma, GOC:tfm, MESH:D004847] subset: human_reference_atlas synonym: "epitheliocyte" EXACT [] xref: BTO:0000414 xref: CALOHA:TS-2026 xref: CARO:0000077 xref: FBbt:00000124 xref: FMA:66768 xref: WBbt:0003672 is_a: CL:0000548 ! animal cell disjoint_from: CL:0000738 ! leukocyte relationship: part_of UBERON:0000483 ! epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000067 name: ciliated epithelial cell def: "An epithelial cell that has a cilia." [GOC:tfm] xref: FMA:70605 is_a: CL:0000064 ! ciliated cell is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: has_part GO:0005929 ! cilium [Term] id: CL:0000068 name: duct epithelial cell def: "An epithelial cell that is part of a duct." [https://orcid.org/0000-0001-5208-3432] is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000058 ! duct relationship: part_of UBERON:0000058 ! duct [Term] id: CL:0000069 name: branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell [Term] id: CL:0000071 name: blood vessel endothelial cell def: "An endothelial cell that lines the vasculature." [GOC:tfm] subset: human_reference_atlas synonym: "cuboidal endothelial cell of vascular tree" EXACT [] is_a: CL:0000076 {is_inferred="true"} ! squamous epithelial cell is_a: CL:0002139 ! endothelial cell of vascular tree intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0004638 ! blood vessel endothelium relationship: develops_from CL:0002546 ! embryonic blood vessel endothelial progenitor cell relationship: part_of UBERON:0004638 ! blood vessel endothelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000072 name: non-branched duct epithelial cell is_a: CL:0000068 ! duct epithelial cell is_a: CL:0002078 ! meso-epithelial cell [Term] id: CL:0000075 name: columnar/cuboidal epithelial cell def: "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GO:0002065, https://orcid.org/0000-0001-5208-3432] subset: human_reference_atlas is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000076 name: squamous epithelial cell xref: CALOHA:TS-1249 is_a: CL:0000066 ! epithelial cell [Term] id: CL:0000077 name: mesothelial cell def: "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." [GOC:tfm, ISBN:0721662544] subset: human_reference_atlas synonym: "mesotheliocyte" EXACT [] xref: FMA:66773 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0000213 ! lining cell is_a: CL:0002078 ! meso-epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000080 name: circulating cell def: "A cell which moves among different tissues of the body, via blood, lymph, or other medium." [GOC:add] is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0000179 ! haemolymphatic fluid relationship: part_of UBERON:0000179 ! haemolymphatic fluid [Term] id: CL:0000081 name: blood cell def: "A cell found predominately in the blood." [GOC:add, GOC:tfm] xref: FMA:62844 xref: MESH:D001773 is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0008015 ! blood circulation relationship: capable_of GO:0008015 ! blood circulation [Term] id: CL:0000082 name: epithelial cell of lung def: "An epithelial cell of the lung." [https://orcid.org/0000-0001-5208-3432] subset: human_reference_atlas synonym: "lung epithelial cell" EXACT [] xref: BTO:0004299 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0000115 ! lung epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000083 name: epithelial cell of pancreas def: "An epithelial cell of the pancreas." [GOC:tfm] synonym: "pancreas epithelial cell" EXACT [] synonym: "pancreatic epithelial cell" EXACT [] xref: BTO:0000028 is_a: CL:0000066 {is_inferred="true"} ! epithelial cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: develops_from CL:0000223 ! endodermal cell relationship: part_of UBERON:0001264 ! pancreas [Term] id: CL:0000084 name: T cell def: "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [GOC:add, GOC:tfm, ISBN:0781735149] subset: human_reference_atlas synonym: "immature T cell" RELATED [] synonym: "mature T cell" RELATED [] synonym: "T lymphocyte" EXACT [] synonym: "T-cell" EXACT [] synonym: "T-lymphocyte" EXACT [] xref: BTO:0000782 xref: CALOHA:TS-1001 xref: FMA:62870 xref: MESH:D013601 xref: VHOG:0001479 is_a: CL:0000542 {is_inferred="true"} ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: capable_of GO:0002456 ! T cell mediated immunity relationship: capable_of GO:0002456 ! T cell mediated immunity relationship: develops_from CL:0000827 ! pro-T cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000095 name: neuron associated cell is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000098 name: sensory epithelial cell def: "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] comment: The term "neuroepithelial cell" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710). synonym: "neuroepithelial cell" BROAD [] xref: BTO:0004301 is_a: CL:0000066 ! epithelial cell is_a: CL:0000197 ! sensory receptor cell is_a: CL:0002371 ! somatic cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000099 name: interneuron def: "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." [GOC:tfm, MESH:D007395] subset: human_reference_atlas xref: BTO:0003811 xref: FBbt:00005125 xref: FMA:67313 xref: WBbt:0005113 is_a: CL:0000540 ! neuron property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000100 name: motor neuron def: "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." [MESH:D009046, PMID:16875686] subset: human_reference_atlas synonym: "motoneuron" EXACT [] xref: BTO:0000312 xref: FBbt:00005123 xref: FMA:83617 xref: WBbt:0005409 is_a: CL:0000527 ! efferent neuron property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000101 name: sensory neuron def: "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." [ISBN:0721662544] xref: BTO:0001037 xref: FBbt:00005124 xref: FMA:84649 xref: MESH:D011984 xref: WBbt:0005759 is_a: CL:0000526 ! afferent neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception [Term] id: CL:0000107 name: autonomic neuron def: "A neuron whose cell body is within an autonomic ganglion." [GOC:tfm] xref: FMA:80121 is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0002410 ! autonomic nervous system relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0002410 ! autonomic nervous system [Term] id: CL:0000108 name: cholinergic neuron def: "A neuron that uses acetylcholine as a vesicular neurotransmitter." [GOC:tfm] xref: BTO:0004902 xref: FBbt:00007173 xref: FMA:84796 xref: MESH:D059329 xref: WBbt:0006840 is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission relationship: capable_of GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: CL:0000115 name: endothelial cell def: "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." [GOC:tfm, http://en.wikipedia.org/wiki/Endothelial_cell, https://sourceforge.net/tracker/?func=detail&atid=440764&aid=3364936&group_id=36855, MESH:D042783, PMID:21275341] comment: From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]. subset: human_reference_atlas synonym: "endotheliocyte" EXACT [] xref: BTO:0001176 xref: CALOHA:TS-0278 xref: FMA:66772 is_a: CL:0000213 ! lining cell is_a: CL:0002078 ! meso-epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000117 name: CNS neuron (sensu Vertebrata) is_a: CL:0000540 ! neuron is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of UBERON:0001017 ! central nervous system [Term] id: CL:0000123 name: neuron associated cell (sensu Vertebrata) is_a: CL:0000095 ! neuron associated cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from CL:0000333 ! migratory neural crest cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: CL:0000125 name: glial cell def: "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." [MESH:D009457] comment: Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571 synonym: "neuroglia" RELATED [] synonym: "neuroglial cell" EXACT [] xref: BTO:0002606 xref: CALOHA:TS-0415 xref: FBbt:00005144 xref: FMA:54536 is_a: CL:0000095 ! neuron associated cell [Term] id: CL:0000126 name: macroglial cell def: "A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together." [GOC:tfm, ISBN:0721662544] synonym: "macrogliocyte" EXACT [] xref: BTO:0000771 xref: CALOHA:TS-2027 xref: FMA:54538 is_a: CL:0000125 ! glial cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from CL:0000339 ! glioblast (sensu Vertebrata) [Term] id: CL:0000128 name: oligodendrocyte def: "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system." [http://en.wikipedia.org/wiki/Oligodendrocyte, MESH:D009836] comment: Oligodendrocytes are reportedly MDP-positive and CD4-negative. subset: human_reference_atlas synonym: "oligodendroglia" RELATED [] synonym: "OLs" EXACT [PMID:8734446] xref: BTO:0000962 xref: CALOHA:TS-0709 xref: FMA:54540 is_a: CL:0000126 {is_inferred="true"} ! macroglial cell is_a: CL:4023154 ! myelinating glial cell relationship: develops_from CL:0002453 ! oligodendrocyte precursor cell relationship: part_of UBERON:0001017 ! central nervous system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000133 name: neurectodermal cell def: "Ectoderm destined to be nervous tissue." [GOC:tfm, ISBN:068340007X] synonym: "neurectoderm cell" EXACT [] is_a: CL:0000221 ! ectodermal cell [Term] id: CL:0000134 name: mesenchymal stem cell def: "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." [FB:ma, GOC:dsd, http://en.wikipedia.org/wiki/Mesenchymal_stem_cell, http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells, PMCID:PMC2613570, PMID:10102814, PMID:16923606, PMID:17986482, PMID:19960544] comment: Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2. synonym: "BMSC" NARROW [] synonym: "bone marrow stromal cells" NARROW [] synonym: "CFU-F" RELATED [] synonym: "colony-forming unit-fibroblast" NARROW [] synonym: "marrow stromal cells" NARROW [PMID:11378515] synonym: "mesenchymal precursor cell" RELATED [] synonym: "mesenchymal progenitor cells" RELATED PLURAL [MESH:D044982] synonym: "mesenchymal stem cell" RELATED [] synonym: "mesenchymal stromal cell" RELATED [] synonym: "mesenchymal stromal cells" RELATED PLURAL [] synonym: "MSC" RELATED [PMID:11378515] synonym: "stem cells, mesenchymal" RELATED PLURAL [MESH:D044982] xref: BTO:0002625 xref: BTO:0003298 xref: FMA:70546 is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002320 {is_inferred="true"} ! connective tissue cell property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/474" xsd:string [Term] id: CL:0000136 name: fat cell def: "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." [MESH:D017667] subset: human_reference_atlas synonym: "adipocyte" EXACT [] synonym: "adipose cell" EXACT [] xref: BTO:0000443 xref: CALOHA:TS-0012 xref: FMA:63880 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000325 ! stuff accumulating cell is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000138 name: chondrocyte def: "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." [GO_REF:0000034, MESH:D019902] synonym: "cartilage cell" EXACT [] xref: BTO:0000249 xref: CALOHA:TS-0138 xref: FMA:66782 is_a: CL:0000153 ! glycosaminoglycan secreting cell is_a: CL:0000667 ! collagen secreting cell relationship: develops_from CL:0000058 ! chondroblast relationship: located_in UBERON:0002418 ! cartilage tissue [Term] id: CL:0000145 name: professional antigen presenting cell def: "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." [GOC:add, ISBN:0781735149] comment: Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells. subset: blood_and_immune_upper_slim synonym: "APC" BROAD [] is_a: CL:0000738 ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: CL:0000146 name: simple columnar epithelial cell subset: human_reference_atlas is_a: CL:0000075 ! columnar/cuboidal epithelial cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000147 name: pigment cell def: "A pigment cell is a cell that contains pigment granules." [GOC:tfm] synonym: "chromatocyte" EXACT [] synonym: "chromatophore" EXACT [] xref: VHOG:0001678 is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000149 name: visual pigment cell synonym: "pigment cell" BROAD [] is_a: CL:0000147 ! pigment cell is_a: CL:0000548 ! animal cell [Term] id: CL:0000150 name: glandular epithelial cell def: "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules." [GOC:tfm] xref: CALOHA:TS-2085 xref: FMA:86494 is_a: CL:0000066 ! epithelial cell is_a: CL:0000151 ! secretory cell is_a: CL:0002371 ! somatic cell relationship: part_of UBERON:0006799 ! glandular epithelium [Term] id: CL:0000151 name: secretory cell def: "A cell that specializes in controlled release of one or more substances." [GOC:tfm, ISBN:0721662544] subset: human_reference_atlas xref: BTO:0003659 xref: FMA:86916 is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0032940 ! secretion by cell relationship: capable_of GO:0032940 ! secretion by cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000152 name: exocrine cell def: "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct." [ISBN:0198547684] xref: FMA:16014 is_a: CL:0000151 ! secretory cell is_a: CL:0000548 ! animal cell intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002365 ! exocrine gland relationship: part_of UBERON:0002365 ! exocrine gland [Term] id: CL:0000153 name: glycosaminoglycan secreting cell def: "A cell that secretes glycosaminoglycans." [GOC:tfm] synonym: "GAG secreting cell" EXACT [] synonym: "hyaluronic acid secreting cell" NARROW [] is_a: CL:0000327 ! extracellular matrix secreting cell is_a: CL:0000447 ! carbohydrate secreting cell [Term] id: CL:0000154 name: protein secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0009306 ! protein secretion relationship: capable_of GO:0009306 ! protein secretion [Term] id: CL:0000157 name: surfactant secreting cell def: "A cell that specializes in secretion of surfactant in the alveoli of the lung." [GOC:tfm, ISBN:0721662544] is_a: CL:0000151 {is_inferred="true"} ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0043129 ! surfactant homeostasis relationship: capable_of GO:0043129 ! surfactant homeostasis [Term] id: CL:0000158 name: club cell def: "A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium." [DOI:10.1183/09031936.00146609, DOI:https\://doi.org/10.1378/chest.12-2762, GOC:tfm, PMID:28128362, PMID:29874100, PMID:7905712] def: "Epithelial progenitor cell of the lung. Club cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Club cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium." [DOI:10.1183/09031936.00146609, DOI:https\://doi.org/10.1378/chest.12-2762, GOC:tfm, PMID:28128362, PMID:7905712] subset: human_reference_atlas synonym: "bronchiolar non-ciliated cell" EXACT [] synonym: "Clara cell" EXACT [] synonym: "club cell of bronchiole" EXACT [] xref: BTO:0004811 xref: FMA:14119 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000157 ! surfactant secreting cell is_a: CL:0002328 {is_inferred="true"} ! bronchial epithelial cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002328 ! bronchial epithelial cell intersection_of: capable_of GO:0032940 ! secretion by cell intersection_of: capable_of GO:0043129 ! surfactant homeostasis intersection_of: has_characteristic PATO:0001789 ! domed intersection_of: has_plasma_membrane_part GO:0005902 ! microvillus relationship: has_characteristic PATO:0001789 ! domed relationship: has_plasma_membrane_part GO:0005902 ! microvillus property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000159 name: seromucus secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000161 name: acid secreting cell is_a: CL:0000151 {is_inferred="true"} ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0046717 ! acid secretion relationship: capable_of GO:0046717 ! acid secretion [Term] id: CL:0000163 name: endocrine cell def: "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." [MESH:D055098] subset: human_reference_atlas synonym: "endocrinocyte" EXACT [] xref: FMA:83809 is_a: CL:0000151 ! secretory cell is_a: CL:0000164 {gci_relation="part_of", gci_filler="UBERON:0000945"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0000160", gci_relation="part_of"} ! enteroendocrine cell is_a: CL:0000164 {gci_filler="UBERON:0001264", gci_relation="part_of"} ! enteroendocrine cell is_a: CL:0000548 ! animal cell relationship: part_of UBERON:0000949 ! endocrine system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000164 name: enteroendocrine cell def: "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." [GOC:tfm, SANBI:mhl] xref: BTO:0003865 xref: FMA:62930 xref: MESH:D019858 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000163 ! endocrine cell [Term] id: CL:0000165 name: neuroendocrine cell def: "A neuron that is capable of some hormone secretion in response to neuronal signals." [MESH:D055099] comment: The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. \n\nThe modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron. {xref="https://www.clinicalkey.com/#!/content/book/3-s2.0-B9780323555968000073", xref="PMID:5342440"} subset: human_reference_atlas synonym: "neurosecretory cell" RELATED [] synonym: "neurosecretory neuron" RELATED [] xref: BTO:0002691 xref: FBbt:00005130 xref: FMA:83810 is_a: CL:0000163 ! endocrine cell is_a: CL:0000527 ! efferent neuron is_a: CL:0000710 ! neurecto-epithelial cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0046879 ! hormone secretion property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000167 name: peptide hormone secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0030072 ! peptide hormone secretion relationship: capable_of GO:0030072 ! peptide hormone secretion [Term] id: CL:0000168 name: insulin secreting cell xref: BTO:0000783 is_a: CL:0000154 ! protein secreting cell is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0030073 ! insulin secretion relationship: capable_of GO:0030073 ! insulin secretion [Term] id: CL:0000169 name: type B pancreatic cell def: "A cell that secretes insulin and is located towards the center of the islets of Langerhans." [GOC:tfm, http://en.wikipedia.org/wiki/Pancreatic_b_cell, ISBN:0517223651] comment: Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression. subset: human_reference_atlas synonym: "B-cell of pancreatic islet" EXACT [FMA:70586] synonym: "beta cell" BROAD [ZFA:0009102] synonym: "beta cell islet" RELATED [MA:0002419] synonym: "beta cell of pancreatic islet" EXACT [FMA:70586] synonym: "insulin-secreting cell" EXACT [FMA:70586] synonym: "pancreatic B cell" EXACT [] synonym: "pancreatic B-cell" EXACT [FMA:70586] synonym: "pancreatic beta cell" EXACT [FMA:70586] synonym: "pancreatic islet core" EXACT [MA:0002419] synonym: "type B enteroendocrine cell" EXACT [FMA:70586] xref: BTO:0000783 xref: EV:0200009 xref: FMA:70586 xref: MA:0002419 xref: ncithesaurus:Beta_Cell is_a: CL:0000168 {is_inferred="true"} ! insulin secreting cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: capable_of GO:0030073 ! insulin secretion intersection_of: part_of UBERON:0000006 ! islet of Langerhans relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000170 name: glucagon secreting cell def: "A cell that secretes glucagon." [GOC:tfm] synonym: "glucagon-secreting cell" EXACT [] xref: FMA:84045 is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070091 ! glucagon secretion relationship: capable_of GO:0070091 ! glucagon secretion [Term] id: CL:0000171 name: pancreatic A cell def: "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon." [GOC:tfm, ISBN:0721662544] subset: human_reference_atlas synonym: "alpha cell of islet of Langerhans" EXACT [] synonym: "pancreatic alpha cell" EXACT [] xref: BTO:0000990 xref: FMA:70585 xref: MESH:D050416 is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000172 name: somatostatin secreting cell is_a: CL:0000167 ! peptide hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070253 ! somatostatin secretion relationship: capable_of GO:0070253 ! somatostatin secretion [Term] id: CL:0000173 name: pancreatic D cell def: "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." [FMA:0517223651, GOC:tfm] subset: human_reference_atlas synonym: "D-cell of pancreatic islet" EXACT [] synonym: "delta cell of islet" EXACT [] synonym: "delta cell of pancreatic islet" EXACT [] synonym: "pancreatic D-cell" EXACT [] synonym: "pancreatic delta cell" EXACT [] synonym: "somatostatin-secreting pancreatic cell" EXACT [] xref: BTO:0000803 xref: FMA:70587 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: develops_from CL:0002351 ! progenitor cell of endocrine pancreas relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000174 name: steroid hormone secreting cell is_a: CL:0000151 ! secretory cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0035929 ! steroid hormone secretion relationship: capable_of GO:0035929 ! steroid hormone secretion [Term] id: CL:0000182 name: hepatocyte def: "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." [GOC:tfm, http://en.wikipedia.org/wiki/Hepatocyte, ISBN:0412046911, MESH:D022781, PMID:19717280] comment: Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive. subset: human_reference_atlas xref: BTO:0000575 xref: CALOHA:TS-0454 xref: FMA:14515 is_a: CL:0000066 ! epithelial cell is_a: CL:0000417 ! endopolyploid cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004119 ! endoderm-derived structure relationship: capable_of GO:0006699 ! bile acid biosynthetic process relationship: capable_of GO:0098754 ! detoxification relationship: develops_from CL:0005026 ! hepatoblast relationship: part_of UBERON:0002107 ! liver property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000183 name: contractile cell def: "A cell whose primary function is to shorten." [FB:ma] is_a: CL:0000003 ! native cell [Term] id: CL:0000187 name: muscle cell def: "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [MESH:D032342] synonym: "muscle fiber" EXACT [] synonym: "myocyte" EXACT [] xref: BTO:0000888 xref: BTO:0000902 xref: CALOHA:TS-2032 xref: FBbt:00005074 xref: FMA:67328 xref: WBbt:0003675 is_a: CL:0000183 ! contractile cell is_a: CL:0000393 ! electrically responsive cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from CL:0000056 ! myoblast [Term] id: CL:0000188 name: cell of skeletal muscle def: "A somatic cell located in skeletal muscle." [GOC:tfm] subset: human_reference_atlas synonym: "skeletal muscle cell" EXACT [] xref: BTO:0004392 xref: CALOHA:TS-2158 xref: FMA:9727 is_a: CL:0002371 ! somatic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0002371 ! somatic cell intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: part_of UBERON:0001134 ! skeletal muscle tissue property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000192 name: smooth muscle cell def: "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." [http://en.wikipedia.org/wiki/Smooth_muscle_cell, MESH:D032389, PMID:9315361] subset: human_reference_atlas synonym: "myocytes, smooth muscle" EXACT [MESH:D032389] synonym: "non-striated muscle cell" BROAD [] synonym: "SMCs" EXACT [PMID:9315361] synonym: "smooth muscle fiber" EXACT [] xref: BTO:0004576 xref: CALOHA:TS-2159 xref: FMA:14072 is_a: CL:0008000 ! non-striated muscle cell is_a: CL:0008007 ! visceral muscle cell relationship: develops_from CL:0000514 ! smooth muscle myoblast property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000197 name: sensory receptor cell def: "A cell that is capable of detection of a stimulus involved in sensory perception." [] synonym: "receptor cell" EXACT [] xref: MESH:D011984 is_a: CL:0000003 ! native cell intersection_of: CL:0000000 ! cell intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: part_of UBERON:0001032 ! sensory system relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: part_of UBERON:0001032 ! sensory system [Term] id: CL:0000199 name: mechanoreceptor cell def: "A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system." [MESH:D008465] synonym: "mechanoreceptor" RELATED [MP:0000972] is_a: CL:0000101 ! sensory neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050974 ! detection of mechanical stimulus involved in sensory perception relationship: capable_of GO:0050974 ! detection of mechanical stimulus involved in sensory perception [Term] id: CL:0000200 name: touch receptor cell is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000199 ! mechanoreceptor cell is_a: CL:4023168 ! somatosensory neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch relationship: capable_of GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch [Term] id: CL:0000206 name: chemoreceptor cell def: "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood." [MESH:D002628] is_a: CL:0000197 ! sensory receptor cell intersection_of: CL:0000197 ! sensory receptor cell intersection_of: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception relationship: capable_of GO:0050907 ! detection of chemical stimulus involved in sensory perception [Term] id: CL:0000207 name: olfactory receptor cell synonym: "odorant receptor cell" EXACT [] synonym: "olfactory receptor neuron" EXACT [] synonym: "olfactory sensory neuron" EXACT [] synonym: "Schultze's cell" EXACT [] xref: BTO:0004185 xref: FMA:67860 xref: MESH:D018034 xref: Wikipedia:Olfactory_receptor_neuron is_a: CL:0000006 ! neuronal receptor cell is_a: CL:0000206 ! chemoreceptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: part_of UBERON:0005725 ! olfactory system [Term] id: CL:0000209 name: taste receptor cell def: "A specialized cell involved in gustatory sensory perception." [GOC:tfm, ISBN:0618947256] synonym: "taste bud cell" EXACT [] xref: FMA:67910 is_a: CL:0000098 ! sensory epithelial cell is_a: CL:0000206 ! chemoreceptor cell is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000206 ! chemoreceptor cell intersection_of: capable_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste relationship: capable_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste [Term] id: CL:0000210 name: photoreceptor cell def: "A cell specialized to detect and transduce light." [MESH:D010786] xref: BTO:0001060 xref: CALOHA:TS-0868 xref: FMA:86740 is_a: CL:0000006 {is_inferred="true"} ! neuronal receptor cell intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0050962 ! detection of light stimulus involved in sensory perception relationship: capable_of GO:0050962 ! detection of light stimulus involved in sensory perception [Term] id: CL:0000211 name: electrically active cell def: "A cell whose function is determined by the generation or the reception of an electric signal." [FB:ma] is_a: CL:0000003 ! native cell [Term] id: CL:0000213 name: lining cell def: "A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism." [JB:jb] synonym: "boundary cell" EXACT [] is_a: CL:0000215 ! barrier cell [Term] id: CL:0000214 name: synovial cell def: "A cell located in the synovial joint." [] synonym: "synoviocyte" EXACT [] xref: CALOHA:TS-0995 is_a: CL:0000213 ! lining cell is_a: CL:0002078 {is_inferred="true"} ! meso-epithelial cell relationship: part_of UBERON:0002217 ! synovial joint [Term] id: CL:0000215 name: barrier cell def: "A cell whose primary function is to prevent the transport of stuff across compartments." [JB:jb] is_a: CL:0000003 ! native cell [Term] id: CL:0000216 name: Sertoli cell def: "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." [MESH:D012708] xref: BTO:0001238 xref: CALOHA:TS-0922 xref: FMA:72298 xref: VHOG:0001348 is_a: CL:0000511 ! androgen binding protein secreting cell is_a: CL:0000630 {is_inferred="true"} ! supporting cell is_a: CL:0002625 ! seminiferous tubule epithelial cell intersection_of: CL:0000630 ! supporting cell intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis [Term] id: CL:0000217 name: insulating cell is_a: CL:0000215 ! barrier cell [Term] id: CL:0000218 name: myelinating Schwann cell def: "A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons." [GOC:cvs, GOC:tfm, MESH:D012583] synonym: "neurilemmal cell" EXACT [] synonym: "peripheral neuroglial cell" BROAD [] synonym: "Schwann cell" BROAD [] xref: CALOHA:TS-0898 xref: FMA:62121 is_a: CL:0000217 ! insulating cell is_a: CL:0002573 ! Schwann cell is_a: CL:4023154 ! myelinating glial cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from CL:0002377 ! immature Schwann cell [Term] id: CL:0000219 name: motile cell def: "A cell that moves by its own activities." [FB:ma] is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0048870 ! cell motility relationship: capable_of GO:0048870 ! cell motility [Term] id: CL:0000221 name: ectodermal cell def: "A cell of the outer of the three germ layers of the embryo." [MESH:D004475] synonym: "ectoderm cell" EXACT [] xref: FMA:72549 is_a: CARO:0000000 ! anatomical entity is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000924 ! ectoderm [Term] id: CL:0000222 name: mesodermal cell def: "A cell of the middle germ layer of the embryo." [MESH:D008648] synonym: "mesoblast" EXACT [] synonym: "mesoderm cell" EXACT [] xref: FMA:72554 is_a: CARO:0000000 ! anatomical entity is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000926 ! mesoderm [Term] id: CL:0000223 name: endodermal cell def: "A cell of the inner of the three germ layers of the embryo." [MESH:D004707] synonym: "endoderm cell" EXACT [] xref: FMA:72555 is_a: CARO:0000000 ! anatomical entity is_a: CL:0002321 ! embryonic cell (metazoa) relationship: part_of UBERON:0000925 ! endoderm [Term] id: CL:0000225 name: anucleate cell def: "A cell that lacks a nucleus." [FB:ma] synonym: "non-nucleated cell" EXACT [] xref: FMA:68647 is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: has_characteristic PATO:0001405 ! anucleate disjoint_from: CL:0002242 ! nucleate cell relationship: has_characteristic PATO:0001405 ! anucleate [Term] id: CL:0000226 name: single nucleate cell def: "A cell with a single nucleus." [FB:ma, GOC:tfm] is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000003 ! native cell intersection_of: has_characteristic PATO:0001407 ! mononucleate relationship: has_characteristic PATO:0001407 ! mononucleate [Term] id: CL:0000227 name: binucleate cell is_a: CL:0000228 ! multinucleate cell intersection_of: CL:0000003 ! native cell intersection_of: has_characteristic PATO:0001406 ! binucleate relationship: has_characteristic PATO:0001406 ! binucleate [Term] id: CL:0000228 name: multinucleate cell def: "A cell with more than one nucleus." [FB:ma] synonym: "syncitium" EXACT [] synonym: "syncytial cell" EXACT [] synonym: "syncytium" EXACT [] xref: AEO:0000203 xref: WBbt:0008074 is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000003 ! native cell intersection_of: has_characteristic PATO:0001908 ! multinucleate relationship: has_characteristic PATO:0001908 ! multinucleate [Term] id: CL:0000232 name: erythrocyte def: "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." [GOC:tfm, MESH:D004912] subset: blood_and_immune_upper_slim subset: human_reference_atlas synonym: "RBC" EXACT [] synonym: "red blood cell" EXACT [] xref: BTO:0000424 xref: CALOHA:TS-0290 xref: FMA:81100 is_a: CL:0000081 ! blood cell is_a: CL:0000329 ! oxygen accumulating cell is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0008015 ! blood circulation intersection_of: capable_of GO:0015671 ! oxygen transport intersection_of: CL:4030045 GO:0005840 ! lacks_part ribosome intersection_of: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 intersection_of: has_characteristic PATO:0002039 ! biconcave relationship: CL:4030045 GO:0005840 ! lacks_part ribosome relationship: CL:4030046 PR:000001945 ! lacks_plasma_membrane_part transferrin receptor protein 1 relationship: develops_from CL:0000558 ! reticulocyte relationship: has_characteristic PATO:0002039 ! biconcave property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000255 name: eukaryotic cell xref: MESH:D005057 is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: CL:0000257 name: Eumycetozoan cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000003 ! native cell intersection_of: only_in_taxon NCBITaxon:142796 ! Eumycetozoa relationship: only_in_taxon NCBITaxon:142796 ! Eumycetozoa [Term] id: CL:0000287 name: eye photoreceptor cell subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000970 ! eye relationship: part_of UBERON:0000970 ! eye property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000293 name: structural cell def: "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism." [TAIR:sr] is_a: CL:0000003 ! native cell [Term] id: CL:0000300 name: gamete def: "A mature sexual reproductive cell having a single set of unpaired chromosomes." [GOC:tfm, ISBN:0721662544] synonym: "haploid germ cell" RELATED [] synonym: "haploid nucleated cell" EXACT [] xref: CALOHA:TS-0395 xref: FBbt:00005412 xref: FMA:18649 is_a: CL:0000413 ! haploid cell is_a: CL:0000586 {is_inferred="true"} ! germ cell intersection_of: CL:0000586 ! germ cell intersection_of: capable_of GO:0009566 ! fertilization intersection_of: has_characteristic PATO:0001375 ! haploid relationship: capable_of GO:0009566 ! fertilization [Term] id: CL:0000306 name: crystallin accumulating cell subset: eye_upper_slim synonym: "lens cell" EXACT [] is_a: CL:0000325 ! stuff accumulating cell [Term] id: CL:0000307 name: tracheal epithelial cell def: "An epithelial cell found in the trachea." [GOC:tfm] comment: This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell' subset: human_reference_atlas synonym: "tracheocyte" EXACT [] xref: FBbt:00005038 xref: FMA:74793 is_a: CL:0002202 {is_inferred="true"} ! epithelial cell of tracheobronchial tree intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from CL:0000377 ! tracheoblast relationship: part_of UBERON:0003126 ! trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000313 name: serous secreting cell def: "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." [GOC:tfm, ISBN:0517223651, ISBN:0721662544] subset: human_reference_atlas synonym: "serous cell" EXACT [] xref: BTO:0003687 xref: FMA:62511 is_a: CL:0000159 ! seromucus secreting cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000319 name: mucus secreting cell synonym: "mucous cell" EXACT [] xref: BTO:0003689 is_a: CL:0000159 ! seromucus secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0070254 ! mucus secretion relationship: capable_of GO:0070254 ! mucus secretion [Term] id: CL:0000325 name: stuff accumulating cell def: "A cell that is specialised to accumulate a particular substance(s)." [FB:ma] subset: ubprop:upper_level is_a: CL:0000003 ! native cell [Term] id: CL:0000327 name: extracellular matrix secreting cell is_a: CL:0000499 ! stromal cell [Term] id: CL:0000329 name: oxygen accumulating cell is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0015671 ! oxygen transport relationship: capable_of GO:0015671 ! oxygen transport [Term] id: CL:0000333 name: migratory neural crest cell def: "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." [MESH:A16.254.600] xref: FMA:86667 is_a: CL:0000219 ! motile cell is_a: CL:0011012 ! neural crest cell is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from CL:0007004 ! premigratory neural crest cell [Term] id: CL:0000335 name: mesenchyme condensation cell def: "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." [GOC:tfm, PMID:5025404] is_a: CL:0008019 ! mesenchymal cell [Term] id: CL:0000339 name: glioblast (sensu Vertebrata) def: "An early neural cell developing from the early ependymal cell of the neural tube." [GOC:tfm, ISBN:0618947256] synonym: "spongioblast" EXACT [] xref: FMA:70564 is_a: CL:0000030 ! glioblast is_a: CL:0000123 ! neuron associated cell (sensu Vertebrata) is_a: CL:0011026 ! progenitor cell [Term] id: CL:0000347 name: scleral cell def: "A cell of the sclera of the eye." [GOC:add] subset: eye_upper_slim is_a: CL:0000293 ! structural cell is_a: CL:0000548 ! animal cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000293 ! structural cell intersection_of: part_of UBERON:0001773 ! sclera relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0001773 ! sclera [Term] id: CL:0000348 name: choroidal cell of the eye def: "A cell of the choroid of the eye." [GOC:add] def: "A structural cell that is part of optic choroid." [GOC:add] subset: eye_upper_slim is_a: CL:0000293 ! structural cell is_a: CL:0000548 ! animal cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000293 ! structural cell intersection_of: part_of UBERON:0001776 ! optic choroid relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0001776 ! optic choroid [Term] id: CL:0000349 name: extraembryonic cell is_a: CARO:0000000 ! anatomical entity is_a: CL:0002371 ! somatic cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0000478 ! extraembryonic structure relationship: part_of UBERON:0000478 ! extraembryonic structure [Term] id: CL:0000351 name: trophoblast cell def: "A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface." [GOC:tfm, MESH:D014327] synonym: "trophoblastic cell" EXACT [] xref: FMA:83028 is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell relationship: part_of UBERON:0000358 ! blastocyst [Term] id: CL:0000352 name: epiblast cell def: "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation." [GOC:tfm, ISBN:0618947256] is_a: CL:0000052 ! totipotent stem cell [Term] id: CL:0000353 name: blastoderm cell def: "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." [MESH:D001756] synonym: "blastomere" EXACT [] xref: BTO:0001473 xref: FMA:72551 is_a: CL:0000007 ! early embryonic cell (metazoa) [Term] id: CL:0000354 name: blastemal cell synonym: "blastema cell" EXACT [] xref: ncithesaurus:Blastemal_Cell is_a: CL:0000048 ! multi fate stem cell [Term] id: CL:0000355 name: multi-potent skeletal muscle stem cell def: "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell." [PMID:18282570] comment: Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo. xref: FMA:86767 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: CL:0000188 ! cell of skeletal muscle intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue [Term] id: CL:0000358 name: sphincter associated smooth muscle cell def: "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [GOC:cjm] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0004590 ! sphincter muscle relationship: part_of UBERON:0004590 ! sphincter muscle [Term] id: CL:0000359 name: vascular associated smooth muscle cell def: "A smooth muscle cell associated with the vasculature." [GOC:dsd, GOC:tfm] subset: human_reference_atlas synonym: "vascular smooth muscle cell" EXACT [] synonym: "VSMC" EXACT [] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0002049 ! vasculature relationship: part_of UBERON:0002049 ! vasculature property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000362 name: epidermal cell def: "An epithelial cell of the integument (the outer layer of an organism)." [Flybase:dsj, MA:ma] synonym: "cell of epidermis" EXACT [FMA:62411] synonym: "epithelial cell of skin" NARROW [FMA:62411] xref: BTO:0001470 xref: CALOHA:TS-0283 xref: FMA:62411 xref: MESH:D000078404 is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0007376 ! outer epithelium relationship: part_of UBERON:0007376 ! outer epithelium [Term] id: CL:0000365 name: animal zygote def: "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." [ISBN:0471245208] synonym: "zygote" BROAD [] xref: BTO:0000854 xref: EHDAA2:0004546 xref: FMA:72395 is_a: CL:0000007 ! early embryonic cell (metazoa) is_a: CL:0010017 ! zygote intersection_of: CL:0010017 ! zygote intersection_of: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: CL:0000377 name: tracheoblast is_a: CL:0000069 ! branched duct epithelial cell [Term] id: CL:0000393 name: electrically responsive cell def: "A cell whose function is determined by its response to an electric signal." [FB:ma] is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000397 name: ganglion interneuron is_a: CL:0000099 {is_inferred="true"} ! interneuron intersection_of: CL:0000099 ! interneuron intersection_of: has_soma_location UBERON:0000045 ! ganglion relationship: has_soma_location UBERON:0000045 ! ganglion [Term] id: CL:0000402 name: CNS interneuron def: "An interneuron that has its cell body in a central nervous system." [doi:10.1016/B978-0-12-817424-1.00001-X] comment: Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system. subset: human_reference_atlas is_a: CL:0000099 {is_inferred="true"} ! interneuron is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000099 ! interneuron intersection_of: has_soma_location UBERON:0001017 ! central nervous system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000404 name: electrically signaling cell def: "A cell that initiates an electrical signal and passes that signal to another cell." [FB:ma] is_a: CL:0000211 ! electrically active cell [Term] id: CL:0000408 name: male gamete xref: BTO:0001277 xref: CALOHA:TS-0949 is_a: CL:0000015 {is_inferred="true"} ! male germ cell is_a: CL:0000300 {is_inferred="true"} ! gamete is_a: CL:0000548 ! animal cell intersection_of: CL:0000015 ! male germ cell intersection_of: capable_of GO:0009566 ! fertilization intersection_of: has_characteristic PATO:0001375 ! haploid [Term] id: CL:0000412 name: polyploid cell def: "A cell whose nucleus, or nuclei, each contain more than two haploid genomes." [FB:ma] is_a: CL:0000003 ! native cell [Term] id: CL:0000413 name: haploid cell def: "A cell whose nucleus contains a single haploid genome." [FB:ma, GOC:tfm] is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: has_characteristic PATO:0001375 ! haploid relationship: has_characteristic PATO:0001375 ! haploid [Term] id: CL:0000417 name: endopolyploid cell is_a: CL:0000412 ! polyploid cell [Term] id: CL:0000447 name: carbohydrate secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000451 name: dendritic cell def: "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." [GOC:add, ISBN:0781735149] subset: human_reference_atlas synonym: "interdigitating cell" RELATED [] synonym: "veiled cell" RELATED [] xref: BTO:0002042 xref: CALOHA:TS-0194 xref: FMA:83036 xref: MESH:D003713 is_a: CL:0000145 ! professional antigen presenting cell is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: capable_of GO:0001816 ! cytokine production intersection_of: capable_of GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: capable_of GO:0019882 ! antigen processing and presentation intersection_of: capable_of GO:0045580 ! regulation of T cell differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: has_characteristic PATO:0001407 ! mononucleate intersection_of: has_part GO:0042613 ! MHC class II protein complex disjoint_from: CL:0000542 ! lymphocyte relationship: capable_of GO:0001816 ! cytokine production relationship: capable_of GO:0045580 ! regulation of T cell differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001003 ! lacks_plasma_membrane_part CD34 molecule relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: has_part GO:0042613 ! MHC class II protein complex property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000457 name: biogenic amine secreting cell is_a: CL:0000151 ! secretory cell [Term] id: CL:0000458 name: serotonin secreting cell def: "A cell type that secretes 5-Hydroxytryptamine (serotonin)." [GOC:tfm, PMID:19630576] synonym: "5-HT secreting cell" EXACT [] synonym: "5-Hydroxytryptamine secreting cell" EXACT [] is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0001820 ! serotonin secretion relationship: capable_of GO:0001820 ! serotonin secretion [Term] id: CL:0000459 name: noradrenergic cell def: "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme." [GOC:tfm, ISBN:068340007X] synonym: "noradrenaline secreting cell" EXACT [] synonym: "norepinephrin secreting cell" EXACT [] synonym: "norepinephrine secreting cell" EXACT [] is_a: CL:0000457 ! biogenic amine secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0048243 ! norepinephrine secretion relationship: capable_of GO:0048243 ! norepinephrine secretion [Term] id: CL:0000488 name: visible light photoreceptor cell def: "A photoreceptor cell that detects visible light." [GOC:tfm] is_a: CL:0000210 ! photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: capable_of GO:0009584 ! detection of visible light relationship: capable_of GO:0009584 ! detection of visible light [Term] id: CL:0000499 name: stromal cell def: "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." [GOC:tfm, MESH:D017154] subset: human_reference_atlas xref: BTO:0002064 xref: FMA:83624 is_a: CARO:0000000 ! anatomical entity is_a: CL:0002320 ! connective tissue cell relationship: develops_from CL:0000134 ! mesenchymal stem cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000502 name: type D enteroendocrine cell def: "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." [MESH:D019864] synonym: "D cell" EXACT [] xref: FMA:62935 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000172 ! somatostatin secreting cell [Term] id: CL:0000506 name: enkephalin secreting cell def: "An endorphine cell that secretes enkephalin." [GO:tfm] is_a: CL:0000507 ! endorphin secreting cell [Term] id: CL:0000507 name: endorphin secreting cell def: "A peptide hormone secreting cell that secretes endorphin." [GO:tfm] is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000508 name: type G enteroendocrine cell def: "An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." [GOC:tfm, ISBN:0517223651, MESH:D019863] synonym: "G cell" EXACT [] xref: BTO:0004108 xref: FMA:67609 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000506 ! enkephalin secreting cell is_a: CL:0000509 ! gastrin secreting cell is_a: CL:0002180 ! mucous cell of stomach relationship: part_of UBERON:0004997 ! mucosa of pyloric antrum [Term] id: CL:0000509 name: gastrin secreting cell def: "A peptide hormone secreting cell that secretes gastrin." [GO:tfm] subset: human_reference_atlas is_a: CL:0000167 ! peptide hormone secreting cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000511 name: androgen binding protein secreting cell def: "A peptide hormone secreting cell that secretes androgen binding protein." [GO:tfm] is_a: CL:0000154 ! protein secreting cell [Term] id: CL:0000513 name: cardiac muscle myoblast def: "A precursor cell destined to differentiate into cardiac muscle cell." [GOC:tfm, MESH:D032386] synonym: "cardiac muscle progenitor cell" EXACT [] synonym: "cardiomyocyte progenitor cell" EXACT [] xref: FMA:84797 is_a: CL:0002494 ! cardiocyte is_a: CL:0010021 ! cardiac myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of UBERON:0001133 ! cardiac muscle tissue [Term] id: CL:0000514 name: smooth muscle myoblast def: "A precursor cell destined to differentiate into smooth muscle myocytes." [GOC:tfm, MESH:D032390] synonym: "myoblast, smooth muscle" EXACT [MESH:D032390] synonym: "satellite cell" RELATED [] xref: FMA:84798 is_a: CL:0000056 {is_inferred="true"} ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000192 ! smooth muscle cell relationship: develops_into CL:0000192 ! smooth muscle cell [Term] id: CL:0000515 name: skeletal muscle myoblast def: "A myoblast that differentiates into skeletal muscle fibers." [SANBI:mhl] synonym: "skeletal myoblast" EXACT [] xref: FMA:84799 is_a: CL:0000056 {is_inferred="true"} ! myoblast is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0008002 ! skeletal muscle fiber relationship: develops_from CL:0000355 ! multi-potent skeletal muscle stem cell relationship: develops_into CL:0008002 ! skeletal muscle fiber [Term] id: CL:0000521 name: fungal cell is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000003 ! native cell intersection_of: only_in_taxon NCBITaxon:4751 ! Fungi disjoint_from: CL:0000548 ! animal cell relationship: only_in_taxon NCBITaxon:4751 ! Fungi [Term] id: CL:0000525 name: syncytiotrophoblast cell def: "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." [GOC:tfm, ISBN:0323052908] subset: human_reference_atlas synonym: "plasmidotrophoblast" EXACT [] synonym: "syncytial trophoblast" EXACT [] synonym: "syntrophoblast" EXACT [] xref: FMA:83043 is_a: CL:0000228 ! multinucleate cell is_a: CL:2000060 ! placental villous trophoblast intersection_of: CL:0000351 ! trophoblast cell intersection_of: has_characteristic PATO:0001908 ! multinucleate property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000526 name: afferent neuron def: "A neuron which conveys sensory information centrally from the periphery." [GOC:tfm, MESH:D009475] subset: human_reference_atlas synonym: "input neuron" EXACT [] xref: FMA:87653 is_a: CL:0000540 ! neuron property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000527 name: efferent neuron def: "A neuron which sends impulses peripherally to activate muscles or secretory cells." [MESH:D009476] synonym: "output neuron" EXACT [] is_a: CL:0000540 ! neuron [Term] id: CL:0000530 name: primary neuron is_a: CL:0000540 ! neuron [Term] id: CL:0000531 name: primary sensory neuron is_a: CL:0000101 ! sensory neuron is_a: CL:0000530 ! primary neuron intersection_of: CL:0000101 ! sensory neuron intersection_of: CL:0000530 ! primary neuron [Term] id: CL:0000540 name: neuron def: "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [http://en.wikipedia.org/wiki/Neuron, MESH:D009474] comment: These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma. subset: human_reference_atlas synonym: "nerve cell" EXACT [] xref: BTO:0000938 xref: CALOHA:TS-0683 xref: FBbt:00005106 xref: FMA:54527 xref: VHOG:0001483 xref: WBbt:0003679 is_a: CL:0000393 ! electrically responsive cell is_a: CL:0000404 ! electrically signaling cell is_a: CL:0002319 ! neural cell relationship: capable_of GO:0019226 ! transmission of nerve impulse relationship: develops_from CL:0000031 {gci_relation="in_taxon", gci_filler="NCBITaxon:7742", xref="https://github.com/obophenotype/cell-ontology/issues/757"} ! neuroblast (sensu Vertebrata) property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000542 name: lymphocyte def: "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [GOC:add, ISBN:0683073696, ISBN:0781735149] comment: Editors note: consider adding taxon constraint to vertebrata (PMID:18025161) subset: human_reference_atlas xref: BTO:0000775 xref: CALOHA:TS-0583 xref: FMA:62863 xref: MESH:D008214 xref: VHOG:0001535 is_a: CL:0000842 ! mononuclear cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000738 ! leukocyte intersection_of: has_characteristic PATO:0001407 ! mononucleate intersection_of: has_part CL:0017500 ! neutrophillic cytoplasm intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0000792 ! heterochromatin disjoint_from: CL:0000766 ! myeloid leukocyte relationship: develops_from CL:0000051 ! common lymphoid progenitor relationship: has_part CL:0017500 ! neutrophillic cytoplasm relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0000792 ! heterochromatin property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000547 name: proerythroblast def: "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." [ISBN:0721601464, MESH:A11.118.290.350.200, PMID:1638021] subset: blood_and_immune_upper_slim synonym: "pronormoblast" RELATED [] synonym: "rubriblast" EXACT [ISBN:0721601464] xref: FMA:83518 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0002242 ! nucleate cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_characteristic PATO:0002505 ! nucleated intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part CL:0017505 ! increased nucleus size intersection_of: has_part GO:0005730 ! nucleolus intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000038 ! erythroid progenitor cell relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part CL:0017505 ! increased nucleus size relationship: has_part GO:0005730 ! nucleolus relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000548 name: animal cell def: "A native cell that is part of some Metazoa." [] subset: ubprop:upper_level synonym: "metazoan cell" EXACT [] is_a: CL:0000255 ! eukaryotic cell intersection_of: CL:0000003 ! native cell intersection_of: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: CL:0000549 name: basophilic erythroblast def: "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers." [GOC:tfm, ISBN:0721601464] synonym: "basophilic normoblast" EXACT [ISBN:0721601464] synonym: "early erythroblast" EXACT [ISBN:0721601464] synonym: "early normoblast" EXACT [ISBN:0721601464] synonym: "prorubricyte" EXACT [ISBN:0721601464] xref: FMA:83505 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000765 {is_inferred="true"} ! erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017503 ! basophilic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: has_part CL:0017503 ! basophilic cytoplasm relationship: has_part GO:0000792 ! heterochromatin relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000550 name: polychromatophilic erythroblast def: "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers." [ISBN:0721601464] synonym: "intermediate erythroblast" EXACT [ISBN:0721601464] synonym: "intermediate normoblast" EXACT [ISBN:0721601464] synonym: "polychromatic erythroblast" EXACT [ISBN:0721601464] synonym: "polychromatic normoblast" EXACT [ISBN:0721601464] synonym: "polychromatophilic normoblast" EXACT [ISBN:0721601464] synonym: "rubricyte" EXACT [ISBN:0721601464] xref: FMA:83506 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000765 {is_inferred="true"} ! erythroblast is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017504 ! polychromatophilic cytoplasm intersection_of: has_part GO:0000792 ! heterochromatin intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: develops_from CL:0000549 ! basophilic erythroblast relationship: has_part CL:0017504 ! polychromatophilic cytoplasm relationship: has_part GO:0000792 ! heterochromatin relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000552 name: orthochromatic erythroblast def: "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." [ISBN:0721601464] synonym: "acidophilic erythroblast" EXACT [ISBN:0721601464] synonym: "eosinophilic erythroblast" EXACT [ISBN:0721601464] synonym: "late erythoblast" EXACT [] synonym: "orthochromatic normoblast" EXACT [ISBN:0721601464] synonym: "pyknotic eto enrythroblast" EXACT [ISBN:0721601464] xref: FMA:84646 is_a: CL:0000765 {is_inferred="true"} ! erythroblast intersection_of: CL:0000765 ! erythroblast intersection_of: has_part CL:0017502 ! acidophilic cytoplasm intersection_of: participates_in GO:0030263 ! apoptotic chromosome condensation relationship: develops_from CL:0000550 ! polychromatophilic erythroblast relationship: has_part CL:0017502 ! acidophilic cytoplasm relationship: participates_in GO:0030263 ! apoptotic chromosome condensation [Term] id: CL:0000553 name: megakaryocyte progenitor cell def: "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." [GOC:dsd, GOC:tfm, ISBN:0721601464] comment: Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative. subset: human_reference_atlas synonym: "CFU-Meg" EXACT [PMID:11722431, PMID:12482498] synonym: "colony-forming unit-megakaryocyte" EXACT [] synonym: "Meg-CFC" EXACT [PMCID:PMC1794060] synonym: "megacaryoblast" EXACT [] synonym: "megacaryocyte progenitor cell" EXACT [] synonym: "megakaryoblast" EXACT [] synonym: "megakaryocytic progenitor cell" EXACT [PMID:12482498] synonym: "MkP" EXACT [PMID:21116988] synonym: "promegacaryocyte" RELATED [] synonym: "promegakaryocyte" RELATED [] xref: BTO:0001164 xref: CALOHA:TS-0610 xref: FMA:84235 xref: MESH:D055016 is_a: CL:0000763 ! myeloid cell is_a: CL:0000839 {is_inferred="true"} ! myeloid lineage restricted progenitor cell intersection_of: CL:0000839 ! myeloid lineage restricted progenitor cell intersection_of: capable_of GO:0007113 ! endomitotic cell cycle intersection_of: capable_of GO:0030219 ! megakaryocyte differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: capable_of GO:0007113 ! endomitotic cell cycle relationship: capable_of GO:0030219 ! megakaryocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000050 ! megakaryocyte-erythroid progenitor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000556 name: megakaryocyte def: "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." [http://en.wikipedia.org/wiki/Megakaryocyte, ISBN:0721601464, MESH:D008533, PMID:31043076] comment: Megakaryocytes are reportedly CD181-positive and CD182-positive. subset: blood_and_immune_upper_slim subset: human_reference_atlas synonym: "megacaryocyte" EXACT [] synonym: "megalocaryocyte" EXACT [] synonym: "megalokaryocyte" EXACT [] xref: BTO:0000843 xref: CALOHA:TS-0611 xref: FMA:83555 is_a: CL:0000763 {is_inferred="true"} ! myeloid cell is_a: CL:4033018 {gci_relation="part_of", gci_filler="UBERON:0000114"} ! lung megakaryocyte disjoint_from: CL:0000764 ! erythroid lineage cell relationship: develops_from CL:0000553 ! megakaryocyte progenitor cell relationship: has_characteristic PATO:0001393 ! euploid property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000558 name: reticulocyte def: "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." [GOC:add, GOC:tfm, PMID:15946868, PMID:2037622] subset: blood_and_immune_upper_slim xref: BTO:0001173 xref: CALOHA:TS-0864 xref: MESH:D012156 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0071971 ! extracellular exosome assembly intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: capable_of GO:0071971 ! extracellular exosome assembly relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000552 ! orthochromatic erythroblast relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0000562 name: nucleate erythrocyte def: "An erythrocyte having a nucleus." [GOC:add, GOc:tfm] synonym: "RBC" BROAD [] synonym: "red blood cell" BROAD [] is_a: CL:0000232 {is_inferred="true"} ! erythrocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000232 ! erythrocyte intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: develops_from CL:0002421 ! nucleated reticulocyte [Term] id: CL:0000566 name: angioblastic mesenchymal cell def: "A mesenchymal stem cell capable of developing into blood vessel endothelium." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive. subset: human_reference_atlas synonym: "angioblast" EXACT [] synonym: "chondroplast" EXACT [] is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0011026 ! progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: has_plasma_membrane_part PR:000001444 ! cadherin-5 intersection_of: has_plasma_membrane_part PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: has_plasma_membrane_part PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 relationship: develops_from CL:0000134 ! mesenchymal stem cell relationship: has_plasma_membrane_part PR:000001444 ! cadherin-5 relationship: has_plasma_membrane_part PR:000002112 ! vascular endothelial growth factor receptor 2 relationship: has_plasma_membrane_part PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000569 name: cardiac mesenchymal cell def: "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." [PMID:18816864] is_a: CL:0008019 ! mesenchymal cell is_a: CL:2000073 ! migratory cardiac neural crest cell intersection_of: CL:0008019 ! mesenchymal cell intersection_of: develops_into CL:0002494 ! cardiocyte relationship: develops_into CL:0002494 ! cardiocyte [Term] id: CL:0000573 name: retinal cone cell def: "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." [MESH:D017949] subset: human_reference_atlas xref: BTO:0001036 xref: CALOHA:TS-0866 xref: FMA:67748 is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: develops_from CL:0002672 ! retinal progenitor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000575 name: corneal epithelial cell def: "An epithelial cell of the cornea." [GOC:tfm] subset: eye_upper_slim subset: human_reference_atlas synonym: "epithelial cell of cornea" EXACT [FMA:70551] xref: BTO:0004298 xref: CALOHA:TS-0173 xref: FMA:70551 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002159 ! general ecto-epithelial cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0001772 ! corneal epithelium relationship: part_of UBERON:0001772 ! corneal epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000586 name: germ cell def: "The reproductive cell in multicellular organisms." [MESH:D005854] xref: BTO:0000535 xref: VHOG:0001534 xref: WBbt:0006796 is_a: CL:0000039 {is_inferred="true"} ! germ line cell relationship: capable_of_part_of GO:0009566 ! fertilization [Term] id: CL:0000593 name: androgen secreting cell def: "A steroid hormone secreting cell that secretes androgen." [GOC:tfm] is_a: CL:0000174 ! steroid hormone secreting cell intersection_of: CL:0000151 ! secretory cell intersection_of: capable_of GO:0035935 ! androgen secretion relationship: capable_of GO:0035935 ! androgen secretion [Term] id: CL:0000595 name: enucleate erythrocyte def: "An erythrocyte lacking a nucleus." [GOC:add, GOC:tfm] synonym: "RBC" BROAD [] synonym: "red blood cell" BROAD [] is_a: CL:0000225 ! anucleate cell is_a: CL:0000232 {is_inferred="true"} ! erythrocyte intersection_of: CL:0000232 ! erythrocyte intersection_of: has_characteristic PATO:0001405 ! anucleate relationship: develops_from CL:0002422 ! enucleated reticulocyte [Term] id: CL:0000604 name: retinal rod cell def: "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." [MESH:D017948] subset: human_reference_atlas xref: BTO:0001024 xref: CALOHA:TS-0870 xref: FMA:67747 is_a: CL:0010009 ! camera-type eye photoreceptor cell relationship: develops_from CL:0002672 ! retinal progenitor cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000622 name: acinar cell def: "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." [GOC:tfm, http://www.copewithcytokines.de] synonym: "acinic cell" EXACT [] synonym: "acinous cell" EXACT [] xref: FMA:83625 xref: MESH:D061354 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000154 ! protein secreting cell relationship: part_of UBERON:0009842 ! glandular acinus [Term] id: CL:0000630 name: supporting cell def: "A cell whose primary function is to support other cell types." [FB:ma, GOC:tfm] synonym: "supportive cell" EXACT [] xref: BTO:0002315 is_a: CL:0000003 ! native cell [Term] id: CL:0000656 name: primary spermatocyte def: "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes." [GOC:tfm, ISBN:0721662544] xref: BTO:0001115 xref: CALOHA:TS-2194 xref: FMA:72292 is_a: CL:0000017 {is_inferred="true"} ! spermatocyte intersection_of: CL:0000017 ! spermatocyte intersection_of: capable_of GO:0007140 ! male meiotic nuclear division intersection_of: has_characteristic PATO:0001394 ! diploid relationship: capable_of GO:0007140 ! male meiotic nuclear division relationship: has_characteristic PATO:0001394 ! diploid [Term] id: CL:0000657 name: secondary spermatocyte def: "One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids." [GOC:tfm, ISBN:0721662544] xref: BTO:0000709 xref: CALOHA:TS-2195 xref: FBbt:00004941 xref: FMA:72293 is_a: CL:0000017 {is_inferred="true"} ! spermatocyte is_a: CL:0000413 ! haploid cell intersection_of: CL:0000017 ! spermatocyte intersection_of: capable_of GO:0007142 ! male meiosis II intersection_of: has_characteristic PATO:0001375 ! haploid relationship: capable_of GO:0007142 ! male meiosis II relationship: develops_from CL:0000656 ! primary spermatocyte [Term] id: CL:0000667 name: collagen secreting cell def: "An extracellular matrix secreting cell that secretes collagen." [GOC:tfm] is_a: CL:0000327 ! extracellular matrix secreting cell [Term] id: CL:0000670 name: primordial germ cell def: "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." [GOC:tfm, PMID:1381289] synonym: "gonocyte" EXACT [] synonym: "primitive germ cell" EXACT [] xref: FMA:70567 is_a: CL:0000039 {is_inferred="true"} ! germ line cell is_a: CL:0000219 {is_inferred="true"} ! motile cell is_a: CL:0000548 ! animal cell intersection_of: CL:0000039 ! germ line cell intersection_of: capable_of GO:0048870 ! cell motility intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo [Term] id: CL:0000675 name: female gamete def: "A mature sexual reproductive cell of the female germline." [GOC:tfm] is_a: CL:0000021 {is_inferred="true"} ! female germ cell is_a: CL:0000300 ! gamete [Term] id: CL:0000680 name: muscle precursor cell def: "A non-terminally differentiated cell that is capable of developing into a muscle cell." [GOC:add] is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0011115 ! precursor cell intersection_of: develops_into CL:0000187 ! muscle cell relationship: develops_from CL:0000222 ! mesodermal cell relationship: develops_into CL:0000187 ! muscle cell [Term] id: CL:0000696 name: PP cell def: "A cell that stores and secretes pancreatic polypeptide hormone." [GOC:tfm, JB:jb, PMID:15153415] synonym: "type F enteroendocrine cell" EXACT [] xref: FMA:62938 xref: FMA:83409 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000167 ! peptide hormone secreting cell [Term] id: CL:0000710 name: neurecto-epithelial cell def: "Epithelial cells derived from neural plate and neural crest." [GOC:tfm] comment: The term "neuroepithelial cell" is used to describe both this cell type and sensory epithelial cell (CL:0000098). synonym: "neuroepithelial cell" BROAD [] xref: BTO:0004301 xref: FMA:70557 is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002077 ! ecto-epithelial cell intersection_of: CL:0002077 ! ecto-epithelial cell intersection_of: develops_from CL:0000133 ! neurectodermal cell relationship: develops_from CL:0000133 ! neurectodermal cell [Term] id: CL:0000723 name: somatic stem cell def: "A stem cell that can give rise to cell types of the body other than those of the germ-line." [GO:0048103] xref: CALOHA:TS-2086 xref: FMA:63368 xref: MESH:D053687 is_a: CL:0000034 {is_inferred="true"} ! stem cell is_a: CL:0002371 ! somatic cell intersection_of: CL:0000034 ! stem cell intersection_of: capable_of GO:0048103 ! somatic stem cell division relationship: capable_of GO:0048103 ! somatic stem cell division [Term] id: CL:0000737 name: striated muscle cell def: "Muscle cell which has as its direct parts myofilaments organized into sarcomeres." [GOC:tfm, ISBN:0721662544] xref: BTO:0002916 xref: CALOHA:TS-2157 xref: FMA:86936 is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0001410 ! striated intersection_of: has_part GO:0030017 ! sarcomere disjoint_from: CL:0008000 ! non-striated muscle cell relationship: has_characteristic PATO:0001410 ! striated relationship: has_part GO:0030017 ! sarcomere [Term] id: CL:0000738 name: leukocyte def: "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [GOC:add, GOC:tfm, ISBN:978-0-323-05290-0] subset: human_reference_atlas synonym: "immune cell" RELATED [] synonym: "leucocyte" EXACT [] synonym: "white blood cell" EXACT [] xref: BTO:0000751 xref: CALOHA:TS-0549 xref: FMA:62852 xref: MESH:D007962 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000219 ! motile cell is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: capable_of GO:0001667 ! ameboidal-type cell migration intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: capable_of GO:0001667 ! ameboidal-type cell migration relationship: develops_from CL:0000037 ! hematopoietic stem cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002405 ! immune system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000740 name: retinal ganglion cell def: "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." [GOC:dph] subset: eye_upper_slim subset: human_reference_atlas synonym: "gangliocyte" EXACT [] synonym: "ganglion cell of retina" EXACT [] synonym: "RGC" EXACT [] xref: BTO:0001800 xref: FMA:67765 xref: MESH:D012165 is_a: CL:0000117 ! CNS neuron (sensu Vertebrata) relationship: has_soma_location UBERON:0000966 ! retina property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000746 name: cardiac muscle cell alt_id: FMA:83808 def: "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." [GOC:mtg_cardiacconduct_nov11, GOC:tfm, ISBN:0323052908, PMID:22426062, PMID:4711263] comment: This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction. subset: human_reference_atlas synonym: "cardiac muscle fiber" EXACT [GO:0048739] synonym: "cardiac myocyte" EXACT [] synonym: "cardiocyte" BROAD [] synonym: "cardiomyocyte" EXACT [] synonym: "heart muscle cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:14067 xref: MESH:D032383 is_a: CL:0000737 ! striated muscle cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0002478 ! transversely striated intersection_of: has_part GO:0030017 ! sarcomere intersection_of: part_of UBERON:0007100 ! primary circulatory organ intersection_of: participates_in GO:0060047 ! heart contraction relationship: develops_from CL:0000513 ! cardiac muscle myoblast relationship: has_characteristic PATO:0002478 ! transversely striated relationship: participates_in GO:0060047 ! heart contraction property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000763 name: myeloid cell def: "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [GOC:add] subset: human_reference_atlas xref: BTO:0001441 xref: CALOHA:TS-0647 xref: MESH:D022423 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000988 {is_inferred="true"} ! hematopoietic cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: develops_from CL:0000049 ! common myeloid progenitor relationship: develops_from CL:0000049 ! common myeloid progenitor property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000764 name: erythroid lineage cell def: "A immature or mature cell in the lineage leading to and including erythrocytes." [GOC:add, GOC:tfm] comment: Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes. subset: human_reference_atlas synonym: "erythropoietic cell" EXACT [] xref: CALOHA:TS-0290 xref: FMA:62845 xref: FMA:83516 is_a: CL:0000763 ! myeloid cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000765 name: erythroblast def: "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." [GOC:add, ISBN:0721601464, PMID:18174176] subset: blood_and_immune_upper_slim synonym: "normoblast" EXACT [] xref: BTO:0001571 xref: CALOHA:TS-0289 xref: FMA:83504 xref: MESH:D004900 is_a: CL:0000764 {is_inferred="true"} ! erythroid lineage cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0000764 ! erythroid lineage cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: CL:4030045 GO:0005730 ! lacks_part nucleolus intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_part GO:0005634 ! nucleus relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: CL:4030045 GO:0005730 ! lacks_part nucleolus relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: develops_from CL:0000547 ! proerythroblast relationship: has_part GO:0005634 ! nucleus [Term] id: CL:0000766 name: myeloid leukocyte def: "A cell of the monocyte, granulocyte, or mast cell lineage." [GOC:add] subset: human_reference_atlas is_a: CL:0000738 {is_inferred="true"} ! leukocyte is_a: CL:0000763 ! myeloid cell intersection_of: CL:0000738 ! leukocyte intersection_of: develops_from CL:0000049 ! common myeloid progenitor property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000827 name: pro-T cell def: "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." [GOC:add, ISBN:0781735149] synonym: "DN1 cell" NARROW [] synonym: "DN1 thymocyte" NARROW [] synonym: "pro-T lymphocyte" EXACT [] synonym: "progenitor T cell" EXACT [] synonym: "TN1 cell" NARROW [] is_a: CL:0000838 {is_inferred="true"} ! lymphoid lineage restricted progenitor cell intersection_of: CL:0000838 ! lymphoid lineage restricted progenitor cell intersection_of: capable_of GO:0030217 ! T cell differentiation relationship: capable_of GO:0030217 ! T cell differentiation relationship: develops_from CL:0000051 ! common lymphoid progenitor [Term] id: CL:0000837 name: hematopoietic multipotent progenitor cell def: "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." [GOC:add, GOC:tfm, PMID:19022770] comment: Markers differ between mouse and human. subset: blood_and_immune_upper_slim subset: human_reference_atlas synonym: "hemopoietic progenitor cell" EXACT [] synonym: "MPP" EXACT [] xref: BTO:0000725 xref: CALOHA:TS-0448 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0008001 ! hematopoietic precursor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000988 ! hematopoietic cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: has_characteristic PATO:0001402 ! multipotent intersection_of: has_plasma_membrane_part PR:000001003 ! CD34 molecule disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001869 ! lacks_plasma_membrane_part interleukin-7 receptor subunit alpha relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: develops_from CL:0000037 ! hematopoietic stem cell relationship: has_characteristic PATO:0001402 ! multipotent relationship: has_plasma_membrane_part PR:000001003 ! CD34 molecule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0000838 name: lymphoid lineage restricted progenitor cell def: "A progenitor cell restricted to the lymphoid lineage." [GOC:add, GOC:tfm] comment: Note that this is a class of cell types, not an identified single cell type. synonym: "lymphoid progenitor cell" BROAD [] xref: BTO:0004731 xref: CALOHA:TS-2025 xref: FMA:70338 is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: capable_of GO:0030098 ! lymphocyte differentiation disjoint_from: CL:0000839 ! myeloid lineage restricted progenitor cell relationship: capable_of GO:0030098 ! lymphocyte differentiation [Term] id: CL:0000839 name: myeloid lineage restricted progenitor cell def: "A progenitor cell restricted to the myeloid lineage." [GOC:add, GOC:tfm, PMID:19022770] comment: Note that this is a class of cell types, not an identified single cell type. synonym: "myeloid progenitor cell" BROAD [] xref: BTO:0004730 xref: CALOHA:TS-2099 xref: FMA:70339 is_a: CL:0002031 {is_inferred="true"} ! hematopoietic lineage restricted progenitor cell is_a: CL:0011026 ! progenitor cell intersection_of: CL:0002031 ! hematopoietic lineage restricted progenitor cell intersection_of: capable_of GO:0030099 ! myeloid cell differentiation relationship: capable_of GO:0030099 ! myeloid cell differentiation [Term] id: CL:0000842 name: mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] subset: blood_and_immune_upper_slim synonym: "mononuclear leukocyte" EXACT [] synonym: "peripheral blood mononuclear cell" NARROW [] xref: BTO:0000878 xref: CALOHA:TS-0768 xref: FMA:86713 is_a: CL:0000226 ! single nucleate cell is_a: CL:0000738 {is_inferred="true"} ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: has_characteristic PATO:0001407 ! mononucleate [Term] id: CL:0000847 name: ciliated olfactory receptor neuron def: "An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob." [PMID:16841163] synonym: "ciliated olfactory sensory neuron" EXACT [] synonym: "ciliated sensory neuron" EXACT [] is_a: CL:0000064 ! ciliated cell is_a: CL:0000207 ! olfactory receptor cell intersection_of: CL:0000207 ! olfactory receptor cell intersection_of: has_part GO:0005929 ! cilium [Term] id: CL:0000850 name: serotonergic neuron def: "A neuron that releases serotonin as a neurotransmitter." [SANBI:mhl] synonym: "5-HT neuron" EXACT [] synonym: "5-hydroxytryptamine neuron" EXACT [] synonym: "serotinergic neuron" RELATED [] xref: FBbt:00005133 xref: MESH:D059326 xref: WBbt:0006837 is_a: CL:0000458 ! serotonin secreting cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0060096 ! serotonin secretion, neurotransmission relationship: capable_of GO:0060096 ! serotonin secretion, neurotransmission [Term] id: CL:0000988 name: hematopoietic cell def: "A cell of a hematopoietic lineage." [GO_REF:0000031, GOC:add] synonym: "haematopoietic cell" EXACT [] synonym: "haemopoietic cell" EXACT [] synonym: "hemopoietic cell" EXACT [] xref: BTO:0000574 xref: CALOHA:TS-2017 xref: FMA:70366 xref: FMA:83598 is_a: CL:0002371 ! somatic cell [Term] id: CL:0001035 name: bone cell def: "A connective tissue cell found in bone." [GO_REF:0000034, GOC:add] subset: human_reference_atlas is_a: CL:0000548 {is_inferred="true"} ! animal cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0001474 ! bone element relationship: dc-contributor https://orcid.org/0000-0001-9990-8331 relationship: part_of UBERON:0001474 ! bone element property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-11-16T04:28:16Z [Term] id: CL:0001060 name: hematopoietic oligopotent progenitor cell, lineage-negative def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." [GOC:tfm, PMID:19022770] is_a: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:0002032 ! hematopoietic oligopotent progenitor cell intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) intersection_of: has_characteristic PATO:0001401 ! oligopotent relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: CL:4030046 PR:000002981 ! lacks_plasma_membrane_part lymphocyte antigen 76 (mouse) relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0001066 name: erythroid progenitor cell, mammalian def: "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." [GOC:add, ISBN:0721601464] synonym: "BFU-E" RELATED [] synonym: "blast forming unit erythroid" RELATED [] synonym: "burst forming unit erythroid" RELATED [] synonym: "CFU-E" RELATED [] synonym: "colony forming unit erythroid" RELATED [] synonym: "erythroid stem cell" RELATED [] xref: BTO:0004911 is_a: CARO:0000006 ! material anatomical entity is_a: CL:0000038 ! erythroid progenitor cell is_a: PR:000050567 ! protein-containing material entity intersection_of: CL:0000038 ! erythroid progenitor cell intersection_of: capable_of GO:0030218 ! erythrocyte differentiation intersection_of: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule intersection_of: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule intersection_of: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M intersection_of: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon intersection_of: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 intersection_of: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule intersection_of: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain intersection_of: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 intersection_of: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 intersection_of: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule intersection_of: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G intersection_of: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 relationship: capable_of GO:0030218 ! erythrocyte differentiation relationship: CL:4030046 PR:000001002 ! lacks_plasma_membrane_part CD19 molecule relationship: CL:4030046 PR:000001004 ! lacks_plasma_membrane_part CD4 molecule relationship: CL:4030046 PR:000001012 ! lacks_plasma_membrane_part integrin alpha-M relationship: CL:4030046 PR:000001020 ! lacks_plasma_membrane_part CD3 epsilon relationship: CL:4030046 PR:000001024 ! lacks_plasma_membrane_part neural cell adhesion molecule 1 relationship: CL:4030046 PR:000001083 ! lacks_plasma_membrane_part CD2 molecule relationship: CL:4030046 PR:000001084 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD8 alpha chain relationship: CL:4030046 PR:000001289 ! lacks_plasma_membrane_part membrane-spanning 4-domains subfamily A member 1 relationship: CL:4030046 PR:000001839 ! lacks_plasma_membrane_part T-cell surface glycoprotein CD5 relationship: CL:4030046 PR:000001889 ! lacks_plasma_membrane_part CD14 molecule relationship: CL:4030046 PR:000002978 ! lacks_plasma_membrane_part lymphocyte antigen 6G relationship: has_plasma_membrane_part PR:000001945 ! transferrin receptor protein 1 [Term] id: CL:0002031 name: hematopoietic lineage restricted progenitor cell def: "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." [GOC:tfm, PMID:19022770] subset: blood_and_immune_upper_slim is_a: CARO:0000000 ! anatomical entity is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: has_characteristic PATO:0001400 ! unipotent disjoint_from: CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002032 ! hematopoietic oligopotent progenitor cell relationship: has_characteristic PATO:0001400 ! unipotent creation_date: 2010-01-06T03:43:20Z [Term] id: CL:0002032 name: hematopoietic oligopotent progenitor cell def: "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities." [GOC:tfm, https://orcid.org/0000-0001-5208-3432, PMID:19022770] comment: This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060). subset: blood_and_immune_upper_slim is_a: CARO:0000000 ! anatomical entity is_a: CL:0008001 ! hematopoietic precursor cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: has_characteristic PATO:0001401 ! oligopotent relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000837 ! hematopoietic multipotent progenitor cell relationship: has_characteristic PATO:0001401 ! oligopotent creation_date: 2010-01-06T03:43:27Z [Term] id: CL:0002064 name: pancreatic acinar cell def: "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules." [GOC:tfm, http://www.copewithcytokines.de/cope.cgi?key=pancreatic%20acinar%20cells, ISBN:0517223651, PMID:20395539] subset: human_reference_atlas synonym: "acinar cell of pancreas" EXACT [] xref: BTO:0000028 xref: CALOHA:TS-0737 xref: FMA:63032 is_a: CL:0000622 {is_inferred="true"} ! acinar cell is_a: CL:1001599 ! pancreas exocrine glandular cell intersection_of: CL:0000622 ! acinar cell intersection_of: part_of UBERON:0001263 ! pancreatic acinus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_part GO:0042589 ! zymogen granule membrane relationship: part_of UBERON:0001263 ! pancreatic acinus property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-06-24T03:16:29Z [Term] id: CL:0002067 name: type A enteroendocrine cell def: "An enteroendocrine cell that produces glucagon." [GOC:tfm, ISBN:0412046911] xref: FMA:62939 is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000170 ! glucagon secreting cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: capable_of GO:0070091 ! glucagon secretion relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T10:48:54Z [Term] id: CL:0002068 name: Purkinje myocyte def: "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter." [FMA:0412046911, GOC:tfm, PMID:19939742] subset: human_reference_atlas synonym: "myocytus conducens cardiacus" EXACT [] synonym: "Purkinje cell fiber" EXACT [] synonym: "Purkinje muscle cell" EXACT [] xref: BTO:0001032 xref: FMA:14146 is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-06-28T08:36:15Z [Term] id: CL:0002072 name: nodal myocyte def: "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." [FMA:67101, GOC:tfm] synonym: "cardiac pacemaker cell" EXACT [GOC:pr] synonym: "myocytus nodalis" EXACT [] synonym: "P cell" EXACT [] synonym: "pacemaker cell" BROAD [] xref: BTO:0004190 xref: FMA:67101 is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T11:41:37Z [Term] id: CL:0002073 name: transitional myocyte def: "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." [FMA:67142, GOC:tfm] xref: FMA:67142 is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T02:39:32Z [Term] id: CL:0002074 name: myocardial endocrine cell def: "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides)." [FMA:67111, GOC:tfm] xref: FMA:67111 is_a: CL:0000163 ! endocrine cell is_a: CL:0002086 ! specialized cardiac myocyte relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-06-29T11:50:47Z [Term] id: CL:0002076 name: endo-epithelial cell def: "An epithelial cell derived from endoderm." [FMA:69075, GOC:tfm] xref: FMA:69075 is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004119 ! endoderm-derived structure relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000223 ! endodermal cell creation_date: 2010-06-29T03:38:14Z [Term] id: CL:0002077 name: ecto-epithelial cell def: "An epithelial cell derived from ectoderm." [FMA:69074, GOC:tfm] xref: FMA:69074 is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: develops_from CL:0000221 ! ectodermal cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000221 ! ectodermal cell creation_date: 2010-06-29T03:38:22Z [Term] id: CL:0002078 name: meso-epithelial cell def: "Epithelial cell derived from mesoderm or mesenchyme." [FMA:69076, GOC:tfm] synonym: "epithelial mesenchymal cell" EXACT [] xref: FMA:69076 is_a: CL:0000066 ! epithelial cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: develops_from CL:0000222 ! mesodermal cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000222 ! mesodermal cell creation_date: 2010-06-29T03:49:14Z [Term] id: CL:0002079 name: pancreatic ductal cell def: "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." [FMA:63099, GOC:tfm, PMID:14740223] subset: human_reference_atlas xref: FMA:63099 is_a: CL:0000069 ! branched duct epithelial cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0001064 ! ventral pancreatic duct relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001064 ! ventral pancreatic duct property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-06-30T08:49:43Z [Term] id: CL:0002080 name: pancreatic centro-acinar cell def: "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types." [GOC:tfm, PMID:12142741, PMID:20018761, PMID:8185160] subset: human_reference_atlas synonym: "centroacinar cell of Langerhans" EXACT [] synonym: "pancreatic centroacinar cell" EXACT [] xref: FMA:62455 is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000083 ! epithelial cell of pancreas intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0001263 ! pancreatic acinus relationship: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001263 ! pancreatic acinus property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-06-30T08:49:52Z [Term] id: CL:0002086 name: specialized cardiac myocyte def: "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." [FMA:67968, GOC:tfm] xref: FMA:67968 is_a: CL:0000746 ! cardiac muscle cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-21T01:33:38Z [Term] id: CL:0002087 name: nongranular leukocyte def: "A leukocyte that lacks granules." [GOC:tfm] subset: blood_and_immune_upper_slim synonym: "agranular leukocyte" EXACT [] xref: FMA:62855 is_a: CL:0000738 {is_inferred="true"} ! leukocyte intersection_of: CL:0000738 ! leukocyte intersection_of: CL:4030045 GO:0030141 ! lacks_part secretory granule relationship: CL:4030045 GO:0030141 ! lacks_part secretory granule relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-07-22T11:30:33Z [Term] id: CL:0002088 name: interstitial cell of Cajal def: "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise." [GOC:tfm, PMID:16460275, PMID:19520112] comment: Some argue this cell type is of mesenchymal origin. subset: human_reference_atlas synonym: "ICC" EXACT [] synonym: "intestinal pacemaker cell" EXACT [GOC:pr] xref: BTO:0003914 xref: FMA:86573 is_a: CL:0000710 {is_inferred="true"} ! neurecto-epithelial cell intersection_of: CL:0000710 ! neurecto-epithelial cell intersection_of: capable_of GO:0043134 ! regulation of hindgut contraction relationship: capable_of GO:0043134 ! regulation of hindgut contraction relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-07-22T03:26:00Z [Term] id: CL:0002092 name: bone marrow cell def: "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." [GOC:tfm, ISBN:0618947256] comment: MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense. xref: BTO:0004850 xref: FMA:83621 xref: MESH:D001854 is_a: CL:0001035 {is_inferred="true"} ! bone cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0001035 ! bone cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002371 ! bone marrow creation_date: 2010-07-22T04:48:15Z [Term] id: CL:0002095 name: hilus cell of ovary def: "A cell in the hilum of the ovary that produces androgens." [GOC:tfm, ISBN:068340007X] subset: human_reference_atlas synonym: "hilar cell of ovary" EXACT [] xref: FMA:18710 is_a: CL:0000593 ! androgen secreting cell is_a: CL:0002132 ! stromal cell of ovary relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-08-23T11:18:18Z [Term] id: CL:0002132 name: stromal cell of ovary def: "A stomal cell of the ovary" [GOC:tfm] synonym: "ovarian stromal cell" EXACT [GOC:cjm] xref: FMA:72299 is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0000992 ! ovary relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000992 ! ovary creation_date: 2010-08-23T12:10:31Z [Term] id: CL:0002139 name: endothelial cell of vascular tree def: "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." [GOC:dsd, GOC:tfm, PMID:12768659] comment: These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive. synonym: "cubodial endothelial cell of vascular tree" NARROW [] synonym: "vascular endothelial cell" EXACT [] xref: BTO:0001854 xref: CALOHA:TS-1106 xref: FMA:67755 is_a: CL:0000115 ! endothelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-24T02:06:40Z [Term] id: CL:0002144 name: capillary endothelial cell def: "An endothelial cell found in capillaries." [GOC:tfm] subset: human_reference_atlas xref: BTO:0004956 xref: CALOHA:TS-0112 xref: FMA:67756 is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0001915 ! endothelium of capillary relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001915 ! endothelium of capillary property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-08-24T10:15:00Z [Term] id: CL:0002145 name: ciliated columnar cell of tracheobronchial tree def: "A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree." [GOC:tfm, ISBN:0517223651] subset: human_reference_atlas xref: FMA:70542 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree is_a: CL:0005012 ! multi-ciliated epithelial cell is_a: CL:4030034 ! respiratory ciliated cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002209 ! intermediate epitheliocyte property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-08-24T03:38:29Z [Term] id: CL:0002148 name: dental pulp cell def: "A cell found within the dental pulp." [GOC:tfm, PMID:36267574] xref: CALOHA:TS-0195 xref: FMA:87170 is_a: CL:0002159 ! general ecto-epithelial cell is_a: CL:0002320 ! connective tissue cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0002159 ! general ecto-epithelial cell intersection_of: part_of UBERON:0001754 ! dental pulp relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001754 ! dental pulp creation_date: 2010-08-24T02:52:09Z [Term] id: CL:0002149 name: epithelial cell of uterus def: "An epithelial cell of the uterus." [GOC:tfm] xref: FMA:256161 is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell intersection_of: CL:0002076 ! endo-epithelial cell intersection_of: part_of UBERON:0000995 ! uterus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000995 ! uterus creation_date: 2010-08-24T10:45:54Z [Term] id: CL:0002159 name: general ecto-epithelial cell def: "Epithelial cells derived from general body ectoderm and ectoderm placodes." [GOC:tfm] xref: FMA:70556 is_a: CL:0002077 ! ecto-epithelial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-26T08:31:08Z [Term] id: CL:0002166 name: epithelial cell of Malassez def: "An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth." [GOC:tfm, ISBN:0517223651, ISBN:0815129521] synonym: "epithelial cell rests of Malassez" EXACT [] synonym: "epithelial debris of Malassez" EXACT [] xref: FMA:62987 is_a: CL:0002159 {is_inferred="true"} ! general ecto-epithelial cell is_a: CL:0002251 ! epithelial cell of alimentary canal relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0011595 ! jaw region creation_date: 2010-08-26T08:51:27Z [Term] id: CL:0002167 name: olfactory epithelial cell def: "A specialized cell involved in sensory perception of smell." [GOC:tfm, PMID:7143026] xref: FMA:67870 is_a: CL:0000098 ! sensory epithelial cell is_a: CL:0000206 ! chemoreceptor cell is_a: CL:0000710 ! neurecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-08-26T01:47:13Z [Term] id: CL:0002178 name: epithelial cell of stomach def: "An epithelial cell found in the lining of the stomach." [GOC:tfm] xref: FMA:62948 is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000945 ! stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000945 ! stomach creation_date: 2010-08-25T03:22:08Z [Term] id: CL:0002180 name: mucous cell of stomach def: "A mucous cell in the epithelium of the stomach." [GOC:tfm] xref: FMA:63464 is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0002178 ! epithelial cell of stomach intersection_of: part_of UBERON:0001199 ! mucosa of stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001199 ! mucosa of stomach creation_date: 2010-08-25T03:38:51Z [Term] id: CL:0002183 name: stem cell of gastric gland def: "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit." [GOC:tfm, ISBN:0517223651] xref: FMA:62953 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: CL:0000152 ! exocrine cell is_a: CL:0002180 ! mucous cell of stomach intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0000325 ! gastric gland relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000325 ! gastric gland creation_date: 2010-08-25T03:57:08Z [Term] id: CL:0002195 name: hepatic stem cell def: "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes)." [GOC:tfm, PMID:26798363] synonym: "HpSC" EXACT abbreviation [PMID:18442648] xref: FMA:86577 is_a: CL:0000048 {is_inferred="true"} ! multi fate stem cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000048 ! multi fate stem cell intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002107 ! liver property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string creation_date: 2010-08-30T02:00:42Z [Term] id: CL:0002202 name: epithelial cell of tracheobronchial tree def: "An epithelial cell of the tracheobronchial tree." [GOC:tfm] subset: human_reference_atlas xref: FMA:66816 is_a: CL:0002632 ! epithelial cell of lower respiratory tract intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-02T02:09:14Z [Term] id: CL:0002209 name: intermediate epitheliocyte def: "An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells." [GOC:tfm, ISBN:0517223651] synonym: "undifferentiated columnar cell of tracheobronchial tree" EXACT [] xref: FMA:69060 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-02T02:53:59Z [Term] id: CL:0002222 name: vertebrate lens cell def: "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye." [GOC:tfm, ISBN:0721662544] subset: eye_upper_slim xref: FMA:70950 is_a: CL:0000066 ! epithelial cell is_a: CL:0000306 ! crystallin accumulating cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000965 ! lens of camera-type eye creation_date: 2010-09-07T10:38:03Z [Term] id: CL:0002224 name: lens epithelial cell def: "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." [GOC:tfm, http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium, ISBN:0721662544] subset: human_reference_atlas xref: FMA:67559 is_a: CL:0000075 {is_inferred="true"} ! columnar/cuboidal epithelial cell is_a: CL:0002222 ! vertebrate lens cell intersection_of: CL:0000075 ! columnar/cuboidal epithelial cell intersection_of: part_of UBERON:0001803 ! epithelium of lens relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001803 ! epithelium of lens property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-07T10:45:47Z [Term] id: CL:0002240 name: marrow fibroblast def: "A fibroblast in the bone marrow." [GOC:tfm] xref: FMA:84377 is_a: CL:0000057 ! fibroblast is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-07T02:25:18Z [Term] id: CL:0002241 name: pulmonary interstitial fibroblast def: "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis." [GOC:tfm] subset: human_reference_atlas synonym: "pulmonary myofibroblast" EXACT [] synonym: "pulmonary septal cell" EXACT [] xref: FMA:84467 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:4030031 ! interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001004 ! respiratory system intersection_of: part_of UBERON:0005169 ! interstitial tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001004 ! respiratory system property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-07T02:29:38Z [Term] id: CL:0002242 name: nucleate cell def: "A cell containing at least one nucleus." [GOC:tfm] xref: FMA:67513 is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_characteristic PATO:0002505 ! nucleated creation_date: 2010-09-07T03:32:33Z [Term] id: CL:0002243 name: smooth muscle cell of sphincter of pupil def: "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells." [GOC:tfm, ISBN:0721662544, ISBN:0721694128] synonym: "smooth muscle fiber of sphincter of pupil" EXACT [] synonym: "smooth muscle fibre of sphincter of pupil" RELATED [] xref: FMA:70611 is_a: CL:0000358 {is_inferred="true"} ! sphincter associated smooth muscle cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001607 ! sphincter pupillae relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000133 ! neurectodermal cell relationship: part_of UBERON:0001607 ! sphincter pupillae creation_date: 2010-09-08T08:53:42Z [Term] id: CL:0002246 name: peripheral blood stem cell def: "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells)." [GOC:tfm] synonym: "PBSC" EXACT [] xref: BTO:0002669 xref: FMA:86711 xref: MESH:D000072916 is_a: CL:0000037 {is_inferred="true"} ! hematopoietic stem cell is_a: CL:0000080 ! circulating cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0000178 ! blood relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000178 ! blood creation_date: 2010-09-07T03:57:09Z [Term] id: CL:0002251 name: epithelial cell of alimentary canal def: "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus." [GOC:tfm, ISBN:0721662544] is_a: CL:0002076 ! endo-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001555 ! digestive tract relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001555 ! digestive tract creation_date: 2010-09-08T09:26:53Z [Term] id: CL:0002252 name: epithelial cell of esophagus def: "An epithelial cell of the esophagus." [GOC:tfm] xref: FMA:63071 is_a: CL:0002251 {is_inferred="true"} ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001043 ! esophagus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001043 ! esophagus creation_date: 2010-09-08T09:28:20Z [Term] id: CL:0002253 name: epithelial cell of large intestine def: "An epithelial cell of the large intestine." [GOC:tfm] synonym: "epithelial cell of colon" RELATED [] xref: BTO:0004297 xref: FMA:256157 is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000059 ! large intestine creation_date: 2010-09-08T09:28:22Z [Term] id: CL:0002254 name: epithelial cell of small intestine def: "An epithelial cell of the small intestine." [GOC:tfm] xref: FMA:256159 is_a: CL:0002563 {is_inferred="true"} ! intestinal epithelial cell intersection_of: CL:0002563 ! intestinal epithelial cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002108 ! small intestine creation_date: 2010-09-08T09:41:46Z [Term] id: CL:0002255 name: stromal cell of endometrium def: "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell." [https://doi.org/10.1038/s41591-020-1040-z, PMID:11331626, PMID:30013421, PMID:30309298, Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)] subset: human_reference_atlas synonym: "endometrial stromal cell" EXACT [] synonym: "endometrial stromal fibroblast" EXACT [PMID:30309298] xref: CALOHA:TS-1266 xref: FMA:86490 is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001295 ! endometrium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_potential_to_directly_develop_into CL:2000002 ! decidual cell relationship: part_of UBERON:0002337 ! endometrial stroma property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-08T09:50:04Z [Term] id: CL:0002262 name: endothelial cell of sinusoid def: "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." [GOC:tfm, ISBN:0618947256] subset: human_reference_atlas xref: FMA:63134 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0003909 ! sinusoid relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003909 ! sinusoid property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-14T10:57:26Z [Term] id: CL:0002264 name: type A cell of stomach def: "A type of enteroendocrine cell found in the stomach that secretes glucagon." [GOC:tfm] xref: FMA:83411 is_a: CL:0002067 ! type A enteroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0002067 ! type A enteroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T10:54:42Z [Term] id: CL:0002265 name: type D cell of colon def: "A D cell located in the colon." [GOC:tfm] synonym: "colon D-cell" EXACT [] synonym: "colonic delta cell" EXACT [] synonym: "delta cell of colon" EXACT [] xref: FMA:268744 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009042 ! enteroendocrine cell of colon intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T11:37:35Z [Term] id: CL:0002266 name: type D cell of small intestine def: "A type D cell of the small intestine." [GOC:tfm] synonym: "delta cell of small intestine" EXACT [] synonym: "small intestine D-cell" EXACT [] synonym: "small intestine delta cell" EXACT [] xref: FMA:268736 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0009006 ! enteroendocrine cell of small intestine intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T01:34:22Z [Term] id: CL:0002267 name: type D cell of stomach def: "A type D cell found in the stomach." [GOC:tfm] synonym: "delta cell of stomach" EXACT [] synonym: "stomach D-cell" EXACT [] synonym: "stomach delta cell" EXACT [] xref: FMA:83410 is_a: CL:0000502 ! type D enteroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0000502 ! type D enteroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-10T01:36:03Z [Term] id: CL:0002275 name: pancreatic PP cell def: "A PP cell located in the islets of the pancreas." [GOC:tfm] comment: The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell. subset: human_reference_atlas synonym: "pancreatic polypeptide-secreting cell" EXACT [] synonym: "PP cell of pancreatic islet" EXACT [] synonym: "PP-cell of pancreatic islet" EXACT [] xref: BTO:0000805 xref: FMA:70588 xref: MESH:D050418 is_a: CL:0000696 ! PP cell is_a: CL:0008024 ! pancreatic endocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: part_of UBERON:0000006 ! islet of Langerhans intersection_of: part_of UBERON:0001264 ! pancreas relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000006 ! islet of Langerhans property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-10T03:30:31Z [Term] id: CL:0002308 name: epithelial cell of skin gland def: "An epithelial cell of a skin gland." [GOC:tfm] synonym: "epithelial cell of gland of skin" EXACT [] xref: FMA:70657 is_a: CL:0002159 ! general ecto-epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002419 ! skin gland relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002419 ! skin gland creation_date: 2010-09-14T12:00:07Z [Term] id: CL:0002319 name: neural cell def: "A cell that is part of the nervous system." [GOC:tfm, ISBN:0618947256] xref: CALOHA:TS-2040 xref: FMA:70333 is_a: CARO:0000000 ! anatomical entity is_a: CL:0002371 ! somatic cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0001016 ! nervous system relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001016 ! nervous system creation_date: 2010-09-15T01:34:57Z [Term] id: CL:0002320 name: connective tissue cell def: "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." [GOC:tfm, ISBN:0618947256] subset: human_reference_atlas xref: CALOHA:TS-2096 xref: FMA:63875 xref: MESH:D003239 is_a: CL:0002371 {is_inferred="true"} ! somatic cell intersection_of: CL:0002371 ! somatic cell intersection_of: part_of UBERON:0002384 ! connective tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002384 ! connective tissue property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-15T03:01:54Z [Term] id: CL:0002321 name: embryonic cell (metazoa) def: "A cell of the embryo." [FMA:0618947256] xref: CALOHA:TS-0263 xref: FMA:82840 xref: FMA:82841 xref: WBbt:0007028 is_a: CL:0000548 ! animal cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-15T03:39:21Z [Term] id: CL:0002328 name: bronchial epithelial cell def: "An epithelial cell of the bronchus." [GOC:tfm] xref: BTO:0002922 is_a: CL:0002202 ! epithelial cell of tracheobronchial tree intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002031 ! epithelium of bronchus creation_date: 2010-09-20T02:00:00Z [Term] id: CL:0002332 name: ciliated cell of the bronchus def: "A ciliated cell of the bronchus." [GOC:tfm, PMID:18757316] subset: human_reference_atlas is_a: CL:0002145 ! ciliated columnar cell of tracheobronchial tree is_a: CL:0002328 ! bronchial epithelial cell intersection_of: CL:0000064 ! ciliated cell intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-20T02:21:12Z [Term] id: CL:0002333 name: neural crest derived fat cell def: "A fat cell derived from a neural crest cell." [GOC:tfm, PMID:17507398] is_a: CL:0000136 ! fat cell is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000136 ! fat cell intersection_of: develops_from CL:0000333 ! migratory neural crest cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000005 ! fibroblast neural crest derived creation_date: 2010-09-20T02:25:25Z [Term] id: CL:0002350 name: endocardial cell def: "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." [GOC:tfm, ISSN:0452-3458] subset: human_reference_atlas synonym: "endocardial endothelial cell" EXACT [] synonym: "endothelial cell of endocardium" EXACT [FMA:75621] xref: FMA:75621 is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0002165 ! endocardium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002165 ! endocardium property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-21T04:33:05Z [Term] id: CL:0002351 name: progenitor cell of endocrine pancreas def: "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1." [GOC:tfm, PMID:20025937, PMID:20217494, PMID:22728667] synonym: "pancreatic endocrine progenitor" EXACT [] synonym: "pancreatic islet progenitor cell" EXACT [] is_a: CL:0000548 ! animal cell is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-21T04:41:06Z [Term] id: CL:0002352 name: gestational hematopoietic stem cell def: "A hematopoietic stem cell that exists during embryogenesis." [GOC:tfm, ISBN:978-60327-246-6] is_a: CL:0000037 ! hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0000922 ! embryo relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000922 ! embryo creation_date: 2010-09-22T09:05:13Z [Term] id: CL:0002359 name: placental hematopoietic stem cell def: "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells." [GOC:tfm, ISBN:978-1-60327-346-6] is_a: CL:0002352 ! gestational hematopoietic stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001987 ! placenta creation_date: 2010-09-22T10:30:02Z [Term] id: CL:0002363 name: keratocyte def: "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate." [GOC:tfm, ISBN:978-0-7020-2958-5] subset: eye_upper_slim subset: human_reference_atlas synonym: "corneal fibroblast" EXACT [] synonym: "corneal keratocyte" EXACT [] is_a: CL:0000005 ! fibroblast neural crest derived intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001777 ! substantia propria of cornea relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001777 ! substantia propria of cornea property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-09-22T01:57:40Z [Term] id: CL:0002368 name: respiratory epithelial cell def: "An endo-epithelial cell of the respiratory tract." [GOC:tfm] synonym: "airway epithelial cell" EXACT [] xref: BTO:0004533 is_a: CL:0002076 {is_inferred="true"} ! endo-epithelial cell intersection_of: CL:0002076 ! endo-epithelial cell intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000065 ! respiratory tract creation_date: 2010-09-23T04:38:49Z [Term] id: CL:0002371 name: somatic cell def: "A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell)." [GOC:tfm, ISBN:0721662544] subset: ubprop:upper_level xref: BTO:0001268 xref: FMA:72300 xref: WBbt:0008378 is_a: CL:0000548 ! animal cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-09-24T09:44:42Z [Term] id: CL:0002372 name: myotube def: "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts." [GOC:dos, GOC:tfm, ISBN:0323052908, PMID:22274696] synonym: "myotubule" EXACT [] synonym: "single cell sarcomere" EXACT [] xref: FBbt:00005812 is_a: CL:0000228 ! multinucleate cell is_a: CL:0000737 ! striated muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0001908 ! multinucleate intersection_of: has_characteristic PATO:0002478 ! transversely striated intersection_of: has_part GO:0030017 ! sarcomere relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_characteristic PATO:0002478 ! transversely striated creation_date: 2010-09-24T01:13:01Z [Term] id: CL:0002375 name: Schwann cell precursor def: "A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19." [GOC:tfm] synonym: "Schwann cell precursor cell" EXACT [] is_a: CL:0000030 ! glioblast is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000333 ! migratory neural crest cell creation_date: 2010-09-24T02:06:10Z [Term] id: CL:0002377 name: immature Schwann cell def: "A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons." [GOC:cvs, GOC:tfm, ISBN:0721662544] synonym: "Schwann cell" BROAD [] xref: ZFA:0001725 is_a: CL:0002573 ! Schwann cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0002375 ! Schwann cell precursor creation_date: 2010-09-24T02:10:31Z [Term] id: CL:0002421 name: nucleated reticulocyte def: "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles." [GOC:tfm, PMID:18182572, PMID:9011180, PMID:9046052] is_a: CL:0000558 {is_inferred="true"} ! reticulocyte is_a: CL:0002242 ! nucleate cell intersection_of: CL:0000558 ! reticulocyte intersection_of: has_characteristic PATO:0002505 ! nucleated relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-10-15T09:24:05Z [Term] id: CL:0002422 name: enucleated reticulocyte def: "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes." [GOC:tfm, ISBN:0-12203-052-4, ISBN:0721601464] xref: CALOHA:TS-0864 xref: FMA:66785 is_a: CL:0000225 ! anucleate cell is_a: CL:0000558 {is_inferred="true"} ! reticulocyte intersection_of: CL:0000558 ! reticulocyte intersection_of: has_characteristic PATO:0001405 ! anucleate intersection_of: has_part GO:0005840 ! ribosome relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_part GO:0005840 ! ribosome creation_date: 2010-10-15T09:24:08Z [Term] id: CL:0002453 name: oligodendrocyte precursor cell def: "A progenitor cell of the central nervous system that can differentiate into oligodendrocytes or type-2 astrocytes. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons." [GOC:tfm, PMID:10704434, PMID:11756508, PMID:20142420, PMID:2182078, PMID:24133281, PMID:9826671] comment: This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991). {xref="PMID:10704434", xref="ISBN:9780702028991", xref="PMID:2182078"} subset: human_reference_atlas synonym: "O-2A/OPC" BROAD [PMID:24133281] synonym: "O2A/OPC" BROAD [PMID:11756508] synonym: "oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell" BROAD [PMID:2253328] synonym: "oligodendrocyte/type-2 astrocyte progenitor cell" BROAD [PMID:24133281] {http://purl.org/dc/terms/contributor="https://orcid.org/0000-0002-0819-0473"} xref: MESH:D000073637 is_a: CL:0011026 ! progenitor cell relationship: dc-contributor https://orcid.org/0000-0002-1773-2692 relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000339 ! glioblast (sensu Vertebrata) property_value: RO:0002175 NCBITaxon:9606 creation_date: 2010-11-10T02:51:34Z [Term] id: CL:0002491 name: auditory epithelial cell def: "A specialized cell involved in auditory sensory perception." [GOC:tfm] is_a: CL:0000098 ! sensory epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2010-12-06T03:18:43Z [Term] id: CL:0002494 name: cardiocyte def: "A cell located in the heart, including both muscle and non muscle cells." [GOC:tfm] comment: From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart. synonym: "heart cell" EXACT [] xref: BTO:0001539 xref: CALOHA:TS-0115 xref: FMA:83808 xref: FMA:84791 is_a: CL:0002371 {is_inferred="true"} ! somatic cell intersection_of: CL:0002371 ! somatic cell intersection_of: part_of UBERON:0007100 ! primary circulatory organ relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0007100 ! primary circulatory organ creation_date: 2010-12-07T09:37:22Z [Term] id: CL:0002503 name: adventitial cell def: "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" [GOC:tfm] xref: BTO:0002441 xref: FMA:84639 is_a: CL:0000630 ! supporting cell is_a: CL:0002320 ! connective tissue cell intersection_of: CL:0002320 ! connective tissue cell intersection_of: part_of UBERON:0005742 ! adventitia relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0005742 ! adventitia creation_date: 2010-12-07T04:03:56Z [Term] id: CL:0002504 name: enteric smooth muscle cell def: "A smooth muscle cell of the intestine." [GOC:tfm] synonym: "intestinal smooth muscle cell" EXACT [] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0000160 ! intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000160 ! intestine creation_date: 2011-01-17T03:39:38Z [Term] id: CL:0002518 name: kidney epithelial cell def: "An epithelial cell of the kidney." [GOC:tfm, KUPO:SJ] xref: KUPO:0001019 is_a: CL:0000066 ! epithelial cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002113 ! kidney relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-08T10:46:34Z [Term] id: CL:0002521 name: subcutaneous fat cell def: "A fat cell that is part of subcutaneous adipose tissue." [GOC:tfm] subset: human_reference_atlas synonym: "subcutaneous adipocyte" EXACT [] is_a: CL:0000136 {is_inferred="true"} ! fat cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000136 ! fat cell intersection_of: part_of UBERON:0002190 ! subcutaneous adipose tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002190 ! subcutaneous adipose tissue property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-02-21T02:51:22Z [Term] id: CL:0002538 name: intrahepatic cholangiocyte def: "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes." [GOC:tfm, PMID:23720296] synonym: "small bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 {is_inferred="true"} ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: part_of UBERON:0004823 ! intrahepatic bile duct epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004823 ! intrahepatic bile duct epithelium creation_date: 2011-02-28T01:20:20Z [Term] id: CL:0002539 name: aortic smooth muscle cell def: "A smooth muscle cell of the aorta." [GOC:tfm] xref: BTO:0004577 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0004178 ! aorta smooth muscle tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004178 ! aorta smooth muscle tissue creation_date: 2011-02-28T01:42:12Z [Term] id: CL:0002540 name: mesenchymal stem cell of the bone marrow def: "A mesenchymal stem cell that is part of the bone marrow." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T01:47:47Z [Term] id: CL:0002541 name: chorionic membrane mesenchymal stem cell def: "A mesenchymal stem cell of the chorionic membrane." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003124 ! chorion membrane creation_date: 2011-02-28T03:04:35Z [Term] id: CL:0002543 name: vein endothelial cell def: "An endothelial cell that is part of the vein." [GOC:tfm] subset: human_reference_atlas synonym: "endothelial cell of vein" EXACT [] synonym: "venous endothelial cell" EXACT [] xref: FMA:62104 xref: KUPO:0001099 is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0001638 ! vein relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001638 ! vein property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-02-28T03:48:11Z [Term] id: CL:0002546 name: embryonic blood vessel endothelial progenitor cell def: "An endothelial progenitor cell that participates in angiogenesis during development." [GOC:tfm] comment: See CL:0002619. is_a: CL:0000222 ! mesodermal cell is_a: CL:0002371 ! somatic cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-02-28T04:20:39Z [Term] id: CL:0002547 name: fibroblast of the aortic adventitia def: "A fibroblast of the aortic adventitia." [GOC:tfm] is_a: CL:1000306 {is_inferred="true"} ! fibroblast of tunica adventitia of artery intersection_of: CL:1000306 ! fibroblast of tunica adventitia of artery intersection_of: part_of UBERON:0004664 ! aorta tunica adventitia relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004664 ! aorta tunica adventitia creation_date: 2011-02-28T04:43:41Z [Term] id: CL:0002548 name: fibroblast of cardiac tissue def: "A fibroblast that is part of the heart." [GOC:tfm] synonym: "cardiac fibroblast" EXACT [] is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:0002494 {is_inferred="true"} ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000948 ! heart relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000948 ! heart creation_date: 2011-02-28T04:57:44Z [Term] id: CL:0002551 name: fibroblast of dermis is_a: CL:0002620 {is_inferred="true"} ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0002067 ! dermis relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002067 ! dermis creation_date: 2011-02-28T05:05:33Z [Term] id: CL:0002552 name: fibroblast of gingiva is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001828 ! gingiva relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001828 ! gingiva creation_date: 2011-02-28T05:09:12Z [Term] id: CL:0002553 name: fibroblast of lung def: "A fibroblast that is part of lung." [GOC:tfm] subset: human_reference_atlas xref: BTO:0000764 xref: CALOHA:TS-0575 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002048 ! lung relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002048 ! lung property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-02-28T05:11:03Z [Term] id: CL:0002556 name: fibroblast of periodontium def: "A fibroblast of the periodontium." [GOC:tfm] is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001758 ! periodontium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001758 ! periodontium creation_date: 2011-02-28T05:19:48Z [Term] id: CL:0002557 name: fibroblast of pulmonary artery def: "A fibroblast of pulmonary artery." [GOC:tfm] is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002012 ! pulmonary artery creation_date: 2011-02-28T05:22:27Z [Term] id: CL:0002563 name: intestinal epithelial cell def: "An epithelial cell of the intestine." [GOC:tfm] is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000160 ! intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001277 ! intestinal epithelium creation_date: 2011-03-01T05:18:31Z [Term] id: CL:0002569 name: mesenchymal stem cell of umbilical cord def: "A mesenchymal stem cell of the umbilical cord." [GOC:tfm] is_a: CL:0000134 ! mesenchymal stem cell is_a: CL:0000349 ! extraembryonic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0003422 ! mesenchyme of umbilical cord relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003422 ! mesenchyme of umbilical cord creation_date: 2011-03-01T09:55:12Z [Term] id: CL:0002570 name: mesenchymal stem cell of adipose tissue def: "A mesenchymal stem cell of adipose tissue." [GOC:tfm] synonym: "mesenchymal stem cell of adipose" EXACT [] is_a: CL:0000134 ! mesenchymal stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0001013 ! adipose tissue relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001013 ! adipose tissue creation_date: 2011-03-01T09:57:17Z [Term] id: CL:0002571 name: hepatic mesenchymal stem cell def: "A mesenchymal stem cell of liver." [GOC:tfm] is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0002195 ! hepatic stem cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-03-01T09:58:51Z [Term] id: CL:0002572 name: vertebral mesenchymal stem cell def: "A mesenchymal stem cell of the vertebrae." [GOC:tfm] is_a: CARO:0000000 ! anatomical entity is_a: CL:0000134 {is_inferred="true"} ! mesenchymal stem cell is_a: CL:0001035 ! bone cell intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0002412 ! vertebra relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002412 ! vertebra creation_date: 2011-03-01T10:40:27Z [Term] id: CL:0002573 name: Schwann cell def: "A glial cell that myelinates or ensheathes axons in the peripheral nervous system." [GOC:tfm, PMID:16807057] comment: A myelinating Schwann cell wraps around a single axon. Myelination occurs in larger diameter axons, while a process called ensheathment occurs on smaller diameter axons in which a single cell wraps around multiple small, unmyelinated axons separating them with a thin layer of cytoplasm. The structure formed is called a Remak bundle. {xref="PMID:16807057"} subset: human_reference_atlas xref: BTO:0001220 xref: CALOHA:TS-0898 xref: MESH:D012583 is_a: CL:0000125 ! glial cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000010 ! peripheral nervous system property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-02T01:19:27Z [Term] id: CL:0002574 name: stromal cell of pancreas def: "A stromal cell of the pancreas." [GOC:tfm] subset: human_reference_atlas is_a: CL:0000499 {is_inferred="true"} ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001264 ! pancreas relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-02T02:40:41Z [Term] id: CL:0002577 name: placental epithelial cell def: "An epithelial cell of the placenta." [GOC:tfm] is_a: CL:0000066 ! epithelial cell is_a: CL:0000349 {is_inferred="true"} ! extraembryonic cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001987 ! placenta creation_date: 2011-03-02T03:21:30Z [Term] id: CL:0002584 name: renal cortical epithelial cell def: "An epithelial cell of the kidney cortex." [GOC:tfm] xref: KUPO:0001016 is_a: CL:0002518 {is_inferred="true"} ! kidney epithelial cell is_a: CL:0002681 {is_inferred="true"} ! kidney cortical cell intersection_of: CL:0002518 ! kidney epithelial cell intersection_of: part_of UBERON:0001225 ! cortex of kidney [Term] id: CL:0002585 name: retinal blood vessel endothelial cell def: "A blood vessel endothelial cell that is part of the retina." [GOC:tfm] subset: eye_upper_slim subset: human_reference_atlas is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell is_a: CL:0009004 ! retinal cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0000966 ! retina relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000966 ! retina property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-06T03:28:27Z [Term] id: CL:0002589 name: smooth muscle cell of the brachiocephalic vasculature def: "A smooth muscle cell of the bachiocephalic vasculature." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001529 ! brachiocephalic artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001529 ! brachiocephalic artery creation_date: 2011-03-06T05:00:58Z [Term] id: CL:0002590 name: smooth muscle cell of the brain vasculature def: "A vascular associated smooth muscle cell of the brain vasculature." [GOC:tfm] is_a: CL:0000359 {is_inferred="true"} ! vascular associated smooth muscle cell is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0000955 ! brain relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000955 ! brain creation_date: 2011-03-06T05:01:20Z [Term] id: CL:0002591 name: smooth muscle cell of the pulmonary artery def: "A smooth muscle of the pulmonary artery." [GOC:tfm] subset: human_reference_atlas xref: BTO:0003336 is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002012 ! pulmonary artery property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-06T05:01:28Z [Term] id: CL:0002594 name: smooth muscle cell of the umbilical artery def: "A smooth muscle cell of the umbilical artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001310 ! umbilical artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001310 ! umbilical artery creation_date: 2011-03-06T05:01:48Z [Term] id: CL:0002595 name: smooth muscle cell of the subclavian artery def: "A smooth muscle cell of the subclavian artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0001533 ! subclavian artery relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001533 ! subclavian artery creation_date: 2011-03-06T05:01:52Z [Term] id: CL:0002596 name: smooth muscle cell of the carotid artery def: "Smooth muscle cell of the carotid artery." [GOC:tfm] is_a: CL:0019018 ! blood vessel smooth muscle cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0005396 ! carotid artery segment relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0005396 ! carotid artery segment creation_date: 2011-03-06T05:01:56Z [Term] id: CL:0002597 name: smooth muscle cell of bladder def: "A smooth muscle cell of the bladder." [GC:tfm] subset: human_reference_atlas xref: KUPO:0001122 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1001319 ! bladder cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-06T05:43:24Z [Term] id: CL:0002598 name: bronchial smooth muscle cell subset: human_reference_atlas xref: BTO:0004402 is_a: CL:0019019 ! tracheobronchial smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002185 ! bronchus property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-06T05:46:39Z [Term] id: CL:0002599 name: smooth muscle cell of the esophagus def: "A smooth muscle cell of the esophagus." [GOC:tfm] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001043 ! esophagus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001043 ! esophagus creation_date: 2011-03-06T05:48:17Z [Term] id: CL:0002600 name: smooth muscle cell of trachea def: "A smooth muscle cell of the trachea." [GOC:tfm] is_a: CL:0019019 ! tracheobronchial smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0003126 ! trachea relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0003126 ! trachea creation_date: 2011-03-06T05:50:28Z [Term] id: CL:0002601 name: uterine smooth muscle cell def: "A smooth muscle cell of the uterus." [GOC:tfm] is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0000995 ! uterus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000995 ! uterus creation_date: 2011-03-06T05:53:28Z [Term] id: CL:0002610 name: raphe nuclei neuron def: "A neuron of the raphe nuclei." [GOC:tfm] is_a: CL:0000117 {is_inferred="true"} ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata) intersection_of: has_soma_location UBERON:0004684 ! raphe nuclei relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_soma_location UBERON:0004684 ! raphe nuclei creation_date: 2011-03-06T07:42:06Z [Term] id: CL:0002612 name: neuron of the ventral spinal cord def: "A neuron of the ventral spinal cord." [GOC:tfm] is_a: CL:0000117 {is_inferred="true"} ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata) intersection_of: has_soma_location UBERON:0002257 ! ventral horn of spinal cord relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_soma_location UBERON:0002257 ! ventral horn of spinal cord creation_date: 2011-03-06T07:46:03Z [Term] id: CL:0002620 name: skin fibroblast def: "A fibroblast of skin." [GOC:tfm] subset: human_reference_atlas xref: BTO:0001255 xref: CALOHA:TS-0935 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002097 ! skin of body relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002097 ! skin of body property_value: RO:0002175 NCBITaxon:9606 creation_date: 2011-03-14T12:31:49Z [Term] id: CL:0002621 name: gingival epithelial cell is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001949 ! gingival epithelium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001949 ! gingival epithelium creation_date: 2011-03-14T12:46:28Z [Term] id: CL:0002625 name: seminiferous tubule epithelial cell def: "A cell of the seminiferous tubule epithelium." [GOC:tfm] is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0004813 ! seminiferous tubule epithelium creation_date: 2011-03-15T11:59:23Z [Term] id: CL:0002631 name: epithelial cell of upper respiratory tract is_a: CL:0002368 {is_inferred="true"} ! respiratory epithelial cell intersection_of: CL:0002368 ! respiratory epithelial cell intersection_of: part_of UBERON:0001557 ! upper respiratory tract relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001557 ! upper respiratory tract creation_date: 2011-06-21T12:28:55Z [Term] id: CL:0002632 name: epithelial cell of lower respiratory tract is_a: CL:0002368 {is_inferred="true"} ! respiratory epithelial cell intersection_of: CL:0002368 ! respiratory epithelial cell intersection_of: part_of UBERON:0001558 ! lower respiratory tract relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001558 ! lower respiratory tract creation_date: 2011-06-21T12:29:31Z [Term] id: CL:0002656 name: glandular cell of endometrium def: "A glandular epithelial cell of the endometrium." [GOC:tfm] xref: FMA:86489 is_a: CL:1001591 ! oviduct glandular cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001295 ! endometrium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0001295 ! endometrium creation_date: 2011-07-08T03:54:08Z [Term] id: CL:0002657 name: glandular cell of esophagus def: "A glandular epithelial cell of the esophagus." [GOC:tfm] xref: FMA:86548 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0002252 {is_inferred="true"} ! epithelial cell of esophagus intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001043 ! esophagus relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T03:55:57Z [Term] id: CL:0002658 name: glandular cell of the large intestine def: "A glandular epithelial cell of the large intestine." [GOC:tfm] xref: FMA:87194 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-08T04:03:01Z [Term] id: CL:0002659 name: glandular cell of stomach def: "A glandular epithelial cell that is part of the stomach." [GOC:tfm] xref: CALOHA:TS-1284 xref: FMA:86554 is_a: CL:0000150 {is_inferred="true"} ! glandular epithelial cell is_a: CL:0002178 ! epithelial cell of stomach intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000945 ! stomach relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-11T01:20:35Z [Term] id: CL:0002663 name: myocardial endocrine cell of atrium def: "A myocardial endocrine cell that is part of the atrium." [GOC:tfm] xref: FMA:83389 is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0002081 ! cardiac atrium creation_date: 2011-07-11T02:45:39Z [Term] id: CL:0002664 name: cardioblast def: "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart." [GOC:tfm, PMID:19745164] comment: Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell. synonym: "cardiovascular progenitor cell" EXACT [PMID:17519333, PMID:19745164] synonym: "CPC" EXACT [PMID:19745164] is_a: CL:0000048 ! multi fate stem cell relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-07-11T03:15:38Z [Term] id: CL:0002672 name: retinal progenitor cell def: "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." [GOC:tfm, PMID:20959166, PMID:21148186] is_a: CL:0000048 ! multi fate stem cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000133 ! neurectodermal cell creation_date: 2011-08-16T02:38:01Z [Term] id: CL:0002673 name: tongue muscle cell def: "A skeletal muscle cell that is part of the tongue." [GOC:tfm, PMID:18816858] is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: part_of UBERON:0000378 ! tongue muscle relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: part_of UBERON:0000378 ! tongue muscle creation_date: 2011-08-16T03:10:02Z [Term] id: CL:0002676 name: neural crest derived neuroblast def: "A neuroblast derived from a neural crest cell." [GOC:tfm, PMID:17407019] is_a: CL:0000031 ! neuroblast (sensu Vertebrata) is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: develops_from CL:0000333 ! migratory neural crest cell creation_date: 2011-08-22T09:24:15Z [Term] id: CL:0002680 name: PP cell of intestine def: "A PP cell found in intestine." [GOC:tfm, PMID:2420136, PMID:728970] is_a: CL:0000696 {is_inferred="true"} ! PP cell is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000696 ! PP cell intersection_of: part_of UBERON:0000160 ! intestine relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 creation_date: 2011-09-27T11:59:01Z [Term] id: CL:0002681 name: kidney cortical cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001225 ! cortex of kidney relationship: dc-contributor https://orcid.org/0000-0002-0956-8634 relationship: part_of UBERON:0001225 ! cortex of kidney creation_date: 2011-10-25T03:49:41Z [Term] id: CL:0005000 name: spinal cord interneuron def: "A CNS interneuron located in the spinal cord." [CL:CVS] comment: Is_a interneuron, part_of UBERON:0002240. is_a: CL:0000402 {is_inferred="true"} ! CNS interneuron intersection_of: CL:0000099 ! interneuron intersection_of: has_soma_location UBERON:0002240 ! spinal cord relationship: has_soma_location UBERON:0002240 ! spinal cord [Term] id: CL:0005009 name: renal principal cell def: "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." [CL:CVS] is_a: CL:0000075 ! columnar/cuboidal epithelial cell is_a: CL:0002518 ! kidney epithelial cell [Term] id: CL:0005012 name: multi-ciliated epithelial cell def: "A ciliated epithelial cell with many cilia." [CL:CVS] synonym: "MCC" BROAD [] synonym: "multi-ciliated cell" BROAD [] synonym: "multiciliated cell" BROAD [] synonym: "multiciliated epithelial cell" EXACT [] is_a: CL:0000067 ! ciliated epithelial cell [Term] id: CL:0005024 name: somatomotor neuron def: "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic." [ZFIN:CVS] synonym: "somatic motor neuron" EXACT [] is_a: CL:0000100 ! motor neuron is_a: CL:0000108 ! cholinergic neuron intersection_of: CL:0000100 ! motor neuron intersection_of: synapsed_to CL:0008002 ! skeletal muscle fiber relationship: part_of RO:0002577 ! system relationship: synapsed_to CL:0008002 ! skeletal muscle fiber [Term] id: CL:0005026 name: hepatoblast def: "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation." [GOC:CVS, https://orcid.org/0000-0003-1940-6740, PMID:18356246, PMID:20483998, PMID:26798363] is_a: CL:0000048 ! multi fate stem cell property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" xsd:string [Term] id: CL:0007000 name: preameloblast def: "Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins." [GO_REF:0000034, PMCID:PMC2737325] comment: unsure of neural crest contribution. In VSAO we have develops_from CL:0000008 is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000548 ! animal cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: adjacent_to UBERON:0001763 ! odontogenic papilla relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: develops_from CL:0002077 ! ecto-epithelial cell relationship: part_of UBERON:0005176 ! tooth enamel organ creation_date: 2012-06-15T01:27:01Z [Term] id: CL:0007001 name: skeletogenic cell def: "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized)." [GO_REF:0000034] comment: Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts) synonym: "scleroblast" EXACT [GO_REF:0000034] is_a: CL:0000003 ! native cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2012-06-15T02:51:27Z [Term] id: CL:0007002 name: precementoblast def: "Skeletogenic cell that has the potential to develop into a cementoblast." [GO_REF:0000034] is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000548 ! animal cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: part_of UBERON:0005176 ! tooth enamel organ creation_date: 2012-06-15T04:37:13Z [Term] id: CL:0007003 name: preodontoblast def: "Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell." [GO_REF:0000034] is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000548 ! animal cell is_a: CL:0011026 ! progenitor cell is_a: UBERON:0010313 ! neural crest-derived structure relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: develops_from CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0005176 ! tooth enamel organ creation_date: 2012-06-15T05:15:11Z [Term] id: CL:0007004 name: premigratory neural crest cell def: "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." [UBERONREF:0000002] is_a: CL:0011012 ! neural crest cell is_a: UBERON:0004121 ! ectoderm-derived structure relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: develops_from CL:0000133 ! neurectodermal cell relationship: part_of UBERON:0002342 ! neural crest creation_date: 2012-06-27T08:27:35Z [Term] id: CL:0007009 name: prechondroblast def: "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells." [GO_REF:0000034] is_a: CL:0000055 ! non-terminally differentiated cell is_a: CL:0000548 ! animal cell relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 creation_date: 2012-06-27T10:44:01Z [Term] id: CL:0008000 name: non-striated muscle cell def: "Any muscle cell in which the fibers are not organised into sarcomeres." [GOC:DOS] subset: human_reference_atlas is_a: CL:0000187 ! muscle cell property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0008001 name: hematopoietic precursor cell def: "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." [GOC:dos] is_a: CL:0000988 ! hematopoietic cell [Term] id: CL:0008002 name: skeletal muscle fiber def: "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:tfm, ISBN:0323052908] xref: MESH:D018485 is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0002372 ! myotube intersection_of: CL:0000187 ! muscle cell intersection_of: has_characteristic PATO:0001908 ! multinucleate intersection_of: has_characteristic PATO:0002478 ! transversely striated intersection_of: has_part GO:0030017 ! sarcomere intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: develops_from CL:0000515 ! skeletal muscle myoblast [Term] id: CL:0008007 name: visceral muscle cell def: "A muscle cell that is part of some visceral muscle." [GOC:dos] xref: FBbt:00005070 is_a: CL:0000187 ! muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:8600004 ! visceral muscle tissue relationship: part_of UBERON:8600004 ! visceral muscle tissue [Term] id: CL:0008008 name: striated visceral muscle cell def: "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods." [GOC:dos] is_a: CL:0000737 ! striated muscle cell is_a: CL:0008007 ! visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: has_characteristic PATO:0001410 {all_some="true"} ! striated [Term] id: CL:0008009 name: transversely striated visceral muscle cell def: "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods." [GOC:dos] is_a: CL:0008008 ! striated visceral muscle cell intersection_of: CL:0008007 ! visceral muscle cell intersection_of: has_characteristic PATO:0002478 {all_some="true"} ! transversely striated relationship: has_characteristic PATO:0002478 ! transversely striated [Term] id: CL:0008017 name: adult skeletal muscle myoblast def: "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers." [PMID:23303905] comment: The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins. synonym: "myogenic precursor cell" BROAD [PMID:23303905] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:0000515 ! skeletal muscle myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0008002 ! skeletal muscle fiber intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue [Term] id: CL:0008019 name: mesenchymal cell def: "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." [] synonym: "mesenchyme cell" EXACT [] is_a: CL:0000219 ! motile cell is_a: CL:0002371 ! somatic cell relationship: capable_of GO:0016477 ! cell migration relationship: part_of UBERON:0003104 ! mesenchyme [Term] id: CL:0008022 name: endocardial cushion cell def: "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves." [PMID:18816864] is_a: CL:0000569 ! cardiac mesenchymal cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000569 ! cardiac mesenchymal cell intersection_of: part_of UBERON:0002062 ! endocardial cushion relationship: part_of UBERON:0002062 ! endocardial cushion [Term] id: CL:0008024 name: pancreatic endocrine cell def: "An endocrine cell that is part of the pancreas." [GOC:dos] subset: human_reference_atlas is_a: CL:0000083 ! epithelial cell of pancreas is_a: CL:0000164 ! enteroendocrine cell intersection_of: CL:0000163 ! endocrine cell intersection_of: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0008025 name: noradrenergic neuron def: "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter." [GOC:dos] is_a: CL:0000459 ! noradrenergic cell is_a: CL:4033050 ! catecholaminergic neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission relationship: capable_of GO:0061533 ! norepinephrine secretion, neurotransmission [Term] id: CL:0008028 name: visual system neuron is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of_part_of GO:0007601 ! visual perception relationship: capable_of_part_of GO:0007601 ! visual perception relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2017-07-09T19:12:36Z [Term] id: CL:0008031 name: cortical interneuron def: "An interneuron that has its soma located in the cerebral cortex." [] synonym: "cerebral cortex interneuron" EXACT [] is_a: CL:0000402 ! CNS interneuron is_a: CL:0010012 ! cerebral cortex neuron is_a: CL:0012001 ! neuron of the forebrain intersection_of: CL:0000099 ! interneuron intersection_of: has_soma_location UBERON:0000956 ! cerebral cortex [Term] id: CL:0008034 name: mural cell def: "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." [Wiki:Mural_cell&oldid=930603194] subset: added_for_HCA subset: human_reference_atlas is_a: CL:0002371 ! somatic cell relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2020-02-29T17:33:55Z [Term] id: CL:0008035 name: microcirculation associated smooth muscle cell is_a: CL:0000359 ! vascular associated smooth muscle cell is_a: CL:0008034 ! mural cell intersection_of: CL:0000359 ! vascular associated smooth muscle cell intersection_of: part_of UBERON:0010523 ! microcirculatory vessel relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 relationship: part_of UBERON:0010523 ! microcirculatory vessel creation_date: 2020-02-29T17:37:00Z [Term] id: CL:0009000 name: sensory neuron of spinal nerve def: "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord." [GOC:nv, GOC:pr] synonym: "spinal sensory neuron" EXACT [] is_a: CL:3000004 ! peripheral sensory neuron intersection_of: CL:0000101 ! sensory neuron intersection_of: has_soma_location UBERON:0001780 ! spinal nerve relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0001780 ! spinal nerve [Term] id: CL:0009001 name: compound eye retinal cell def: "Any cell in the compound eye, a light sensing organ composed of ommatidia." [] xref: GOC:pr xref: PMID:12021768 is_a: CL:0009004 ! retinal cell [Term] id: CL:0009004 name: retinal cell def: "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:pr] xref: PMID:10702418 is_a: CL:0002319 ! neural cell intersection_of: CL:0002319 ! neural cell intersection_of: part_of UBERON:0005388 ! photoreceptor array relationship: part_of UBERON:0005388 ! photoreceptor array [Term] id: CL:0009006 name: enteroendocrine cell of small intestine def: "An enteroendocrine cell that is located in the small intestine." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "small intestine enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell is_a: CL:1001598 ! small intestine glandular cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009018 name: lymphocyte of large intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the large intestine." [https://orcid.org/0000-0003-4183-8865] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: human_reference_atlas subset: location_grouping synonym: "lamina propria lymphocyte of large intestine" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0011189 ! lamina propria of large intestine property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0009019 name: nephrogenic zone cell def: "A kidney cortical cell that is part of the nephrogenic zone." [https://orcid.org/0000-0002-3163-0115, PMID:29449449] subset: added_for_HCA synonym: "cortical nephrogenic niche cell" EXACT [] synonym: "cortical nephrogenic zone cell" EXACT [] is_a: CL:0002681 ! kidney cortical cell intersection_of: CL:0002681 ! kidney cortical cell intersection_of: part_of UBERON:0009871 ! nephrogenic zone relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0009871 ! nephrogenic zone [Term] id: CL:0009021 name: stromal cell of lamina propria of large intestine def: "A stromal cell found in the lamina propria of the large intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0011189 ! lamina propria of large intestine [Term] id: CL:0009022 name: stromal cell of lamina propria of small intestine def: "A stromal cell found in the lamina propria of the small intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping is_a: CL:0000499 ! stromal cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001238 ! lamina propria of small intestine [Term] id: CL:0009024 name: mesothelial cell of small intestine def: "A mesothelial cell that is part of the small intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping is_a: CL:0000077 ! mesothelial cell is_a: CL:0002254 ! epithelial cell of small intestine is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009025 name: mesothelial cell of colon def: "A mesothelial cell that is part of the colon." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "mesothelial cell of large intestine" BROAD [] is_a: CL:0000077 ! mesothelial cell is_a: CL:0011108 ! colon epithelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009040 name: stromal cell of lamina propria of colon def: "A stromal cell found in the lamina propria of the colon." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "stromal cell of colon lamina propria" EXACT [] is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0007177 ! lamina propria of mucosa of colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0007177 ! lamina propria of mucosa of colon [Term] id: CL:0009042 name: enteroendocrine cell of colon def: "An enteroendocrine cell that is located in the colon." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "colon enteroendocrine cell" EXACT [] is_a: CL:1001516 ! intestinal enteroendocrine cell is_a: CL:1001588 ! colon glandular cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 [Term] id: CL:0009044 name: lymphocyte of small intestine lamina propria def: "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response." [https://orcid.org/0000-0003-4183-8865, PMID:26551552] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: location_grouping synonym: "gastrointestinal tract (lamina propria) lymphocyte of small intestine" EXACT [] synonym: "gastrointestinal tract small intestine (lamina propria) leukocyte" BROAD [] synonym: "lamina propria lymphocyte of small intestine" EXACT [] synonym: "small intestine lamina propria leukocyte" BROAD [] synonym: "small intestine lamina propria leukocyte (LPL)" BROAD [] synonym: "small intestine lamina propria lymphocyte" EXACT [] is_a: CL:0000542 ! lymphocyte intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0001238 ! lamina propria of small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001238 ! lamina propria of small intestine [Term] id: CL:0009051 name: T cell of anorectum def: "A T cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] comment: This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you. subset: location_grouping is_a: CL:0000084 ! T cell intersection_of: CL:0000084 ! T cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009052 name: smooth muscle cell of anorectum def: "A smooth muscle cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "anorectum smooth muscle cell" EXACT [] is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009053 name: stromal cell of anorectum lamina propria def: "A stromal cell found in the lamina propria of the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping is_a: CL:0009021 ! stromal cell of lamina propria of large intestine intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0011189 ! lamina propria of large intestine intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009063 name: enteroendocrine cell of anorectum def: "An enteroendocrine cell that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "anorectum enteroendocrine cell" EXACT [] is_a: CL:0002658 ! glandular cell of the large intestine is_a: CL:1001516 ! intestinal enteroendocrine cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: CL:0009084 name: epithelial cell of endometrial gland def: "An epithelial cell that is part of an endometrial gland." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "endometrial glandular epithelial cell" EXACT [] xref: EFO:0010710 is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002451 ! endometrial gland relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0002451 ! endometrial gland property_value: http://purl.org/dc/terms/date "2021-11-30T16:13:30Z" xsd:dateTime [Term] id: CL:0009092 name: endothelial cell of placenta def: "An endothelial cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "placental endothelial cell" EXACT [] xref: EFO:0010708 is_a: CL:0000115 ! endothelial cell is_a: CL:0002577 ! placental epithelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 property_value: http://purl.org/dc/terms/date "2021-12-13T13:53:01Z" xsd:dateTime [Term] id: CL:0009093 name: smooth muscle cell of placenta def: "A smooth muscle cell that is part of a placenta." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "placental smooth muscle cell" EXACT [] xref: EFO:0010709 is_a: CL:0000192 ! smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001987 ! placenta property_value: http://purl.org/dc/terms/date "2021-12-13T13:56:42Z" xsd:dateTime [Term] id: CL:0009094 name: endothelial cell of hepatic portal vein def: "An endothelial cell that is part of a hepatic portal vein." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865, PMID:30348985] subset: location_grouping synonym: "portal endothelial cell" BROAD [] xref: EFO:0010704 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001639 ! hepatic portal vein relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001639 ! hepatic portal vein property_value: http://purl.org/dc/terms/date "2021-12-13T14:01:05Z" xsd:dateTime [Term] id: CL:0009095 name: endothelial cell of uterus def: "An endothelial cell that is part of a uterus." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "uterine endothelial cell" EXACT [] xref: EFO:0010711 is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000995 ! uterus relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0000995 ! uterus property_value: http://purl.org/dc/terms/date "2021-12-13T14:39:25Z" xsd:dateTime [Term] id: CL:0009097 name: embryonic skeletal muscle fiber def: "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development." [http://orcid.org/0000-0003-2034-601X, PMID:32094117, PMID:7196501] is_a: CL:0008002 ! skeletal muscle fiber intersection_of: CL:0008002 ! skeletal muscle fiber intersection_of: existence_starts_and_ends_during UBERON:0000068 ! embryo stage relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: existence_starts_and_ends_during UBERON:0000068 ! embryo stage property_value: http://purl.org/dc/terms/date "2022-02-21T15:39:10Z" xsd:dateTime [Term] id: CL:0009100 name: hepatic portal fibroblast def: "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen." [https://orcid.org/0000-0001-7655-4833, PMID:20209607, PMID:24814904] synonym: "portal fibroblast" BROAD [] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001279 ! portal triad relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001279 ! portal triad property_value: http://purl.org/dc/terms/date "2022-03-17T12:00:44Z" xsd:dateTime [Term] id: CL:0010001 name: stromal cell of bone marrow def: "A stromal cell that is part_of a bone marrow." [] synonym: "bone marrow stromal cell" EXACT [] is_a: CL:0000499 ! stromal cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000499 ! stromal cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 [Term] id: CL:0010002 name: epithelial cell of umbilical artery def: "An epithelial cell that is part_of a umbilical artery." [] synonym: "umbilical artery epithelial cell" EXACT [] is_a: CL:0000066 ! epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001310 ! umbilical artery relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 relationship: part_of UBERON:0001310 ! umbilical artery [Term] id: CL:0010004 name: mononuclear cell of bone marrow def: "A mononuclear cell that is part_of a bone marrow." [] synonym: "bone marrow mononuclear cell" EXACT [] is_a: CL:0000842 ! mononuclear cell is_a: CL:1001610 ! bone marrow hematopoietic cell intersection_of: CL:0000842 ! mononuclear cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 [Term] id: CL:0010006 name: cardiac blood vessel endothelial cell is_a: CL:0000071 ! blood vessel endothelial cell is_a: CL:0010008 ! cardiac endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0000948 ! heart [Term] id: CL:0010007 name: His-Purkinje system cell is_a: CL:0000548 ! animal cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0004146 ! His-Purkinje system relationship: part_of UBERON:0004146 ! His-Purkinje system [Term] id: CL:0010008 name: cardiac endothelial cell subset: human_reference_atlas is_a: CL:0000115 ! endothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0010009 name: camera-type eye photoreceptor cell synonym: "camera type eye photoreceptor cell" EXACT [] is_a: CL:0000287 ! eye photoreceptor cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: CL:0010012 name: cerebral cortex neuron def: "A CNS neuron of the cerebral cortex." [GOC:tfm] subset: human_reference_atlas synonym: "cortical neuron" EXACT [] synonym: "neuron of cerebral cortex" EXACT [] xref: BTO:0004102 xref: FMA:84104 is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0000956 ! cerebral cortex relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0000956 ! cerebral cortex property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/cell-ontology/issues/1359" xsd:string [Term] id: CL:0010017 name: zygote def: "A zygote in a plant or an animal." [] xref: MESH:D015053 is_a: CL:0000003 ! native cell property_value: seeAlso https://github.com/obophenotype/cell-ontology/issues/786 [Term] id: CL:0010020 name: cardiac glial cell is_a: CL:0000125 ! glial cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000125 ! glial cell intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart [Term] id: CL:0010021 name: cardiac myoblast xref: MESH:D032386 is_a: CL:0000056 ! myoblast intersection_of: CL:0000056 ! myoblast intersection_of: develops_into CL:0000746 ! cardiac muscle cell relationship: develops_into CL:0000746 ! cardiac muscle cell [Term] id: CL:0010022 name: cardiac neuron def: "A neuron that has its soma in the heart." [PMID:12486170, PMID:29265764] comment: This term is used in 3 GO terms that were created as part of the heart development focus project. is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0000948 ! heart relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0000948 ! heart property_value: seeAlso "https://github.com/obophenotype/cell-ontology/pull/1488" xsd:string [Term] id: CL:0011001 name: spinal cord motor neuron def: "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [GOC:nv] is_a: CL:0000100 {is_inferred="true"} ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: has_soma_location UBERON:0002240 ! spinal cord relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0002240 ! spinal cord [Term] id: CL:0011007 name: paraxial cell def: "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites." [GOC:NV, PMID:11687492] synonym: "paraxial mesoderm cell" EXACT [] synonym: "presomitic mesoderm cell" NARROW [] synonym: "somitic mesoderm cell" EXACT [] is_a: CL:0000222 ! mesodermal cell intersection_of: CL:0000222 ! mesodermal cell intersection_of: part_of UBERON:0003059 ! presomitic mesoderm relationship: part_of UBERON:0003059 ! presomitic mesoderm [Term] id: CL:0011012 name: neural crest cell def: "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." [https://orcid.org/0000-0001-5208-3432, https://orcid.org/0000-0002-9900-7880] is_a: CL:0000048 ! multi fate stem cell is_a: CL:0002321 ! embryonic cell (metazoa) [Term] id: CL:0011013 name: motile sperm cell def: "A sperm cell that is cabaple of motion (motility)." [PMID:30612620] is_a: CL:0000019 ! sperm is_a: CL:0000219 ! motile cell intersection_of: CL:0000019 ! sperm intersection_of: capable_of GO:0097722 ! sperm motility relationship: capable_of GO:0097722 ! sperm motility relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011016 name: flagellated sperm cell def: "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion." [https://www.lexico.com/en/definition/flagellum, PMID:30612620] is_a: CL:0011013 ! motile sperm cell intersection_of: CL:0011013 ! motile sperm cell intersection_of: capable_of GO:0030317 ! flagellated sperm motility relationship: capable_of GO:0030317 ! flagellated sperm motility relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011019 name: mesothelial cell of epicardium def: "A mesothelial cell that is part of the epicardium." [] is_a: CL:0000077 ! mesothelial cell is_a: CL:0002494 ! cardiocyte intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002348 ! epicardium relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: part_of UBERON:0002348 ! epicardium [Term] id: CL:0011021 name: fibroblast of upper back skin def: "A fibroblast that is part of upper back skin." [] is_a: CL:0011022 ! fibroblast of skin of back intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0009015 ! upper back skin relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: part_of UBERON:0009015 ! upper back skin [Term] id: CL:0011022 name: fibroblast of skin of back def: "A fibroblast that is part of skin of back." [] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001068 ! skin of back relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: part_of UBERON:0001068 ! skin of back [Term] id: CL:0011026 name: progenitor cell def: "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." [https://doi.org/10.1016/B978-0-12-409503-8.00002-0, ISBN:978-1-62808-994-3] is_a: CARO:0000000 ! anatomical entity is_a: CL:0011115 ! precursor cell intersection_of: CL:0011115 ! precursor cell intersection_of: develops_from CL:0000034 ! stem cell relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: develops_from CL:0000034 ! stem cell [Term] id: CL:0011027 name: skeletal muscle fibroblast def: "Any fibroblast that is part of skeletal muscle tissue." [https://orcid.org/0000-0001-6164-0667, PMID:28369879] synonym: "skeleton muscle fibroblast" EXACT [] is_a: CL:0000188 ! cell of skeletal muscle is_a: CL:1001609 ! muscle fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001134 ! skeletal muscle tissue relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011030 name: dermal microvascular endothelial cell def: "Any microvascular endothelial cell that is part of the dermis." [BTO:0004574, CL:patterns/cellPartOfAnatomicalEntity] synonym: "dermal microvascular endothelium cell" EXACT [] synonym: "DMEC cell" EXACT [] is_a: CL:2000008 ! microvascular endothelial cell is_a: CL:2000010 ! dermis blood vessel endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0002067 ! dermis relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 [Term] id: CL:0011101 name: chorionic trophoblast cell def: "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [GOC:NV] is_a: CL:0000351 ! trophoblast cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000351 ! trophoblast cell intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: part_of UBERON:0003124 ! chorion membrane [Term] id: CL:0011108 name: colon epithelial cell def: "Epithelial cell that is part of the colon epithelium." [GOC:NV] synonym: "colonic epithelial cell" EXACT [] is_a: CL:0002253 ! epithelial cell of large intestine intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0000397 ! colonic epithelium [Term] id: CL:0011115 name: precursor cell def: "A cell that, by division or terminal differentiation, can give rise to other cell types." [GOC:dos] comment: Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell. is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: capable_of GO:0030154 ! cell differentiation relationship: capable_of GO:0030154 ! cell differentiation [Term] id: CL:0012001 name: neuron of the forebrain def: "A CNS neuron of the forebrain." [] subset: human_reference_atlas synonym: "forebrain neuron" EXACT [] is_a: CL:0000117 {is_inferred="true"} ! CNS neuron (sensu Vertebrata) is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000117 ! CNS neuron (sensu Vertebrata) intersection_of: has_soma_location UBERON:0001890 ! forebrain relationship: dc-contributor https://orcid.org/0000-0002-3837-8864 relationship: has_soma_location UBERON:0001890 ! forebrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0017500 name: neutrophillic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain." [GOC:add] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0070046 ! neutrophillic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_characteristic PATO:0070046 ! neutrophillic creation_date: 2010-05-25T01:36:34Z [Term] id: CL:0017502 name: acidophilic cytoplasm def: "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain." [GOC:add] synonym: "eosinophilic" NARROW [] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0002418 ! acidophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_characteristic PATO:0002418 ! acidophilic creation_date: 2009-12-22T04:23:25Z [Term] id: CL:0017503 name: basophilic cytoplasm def: "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0002094 ! basophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_characteristic PATO:0002094 ! basophilic creation_date: 2009-12-22T04:24:54Z [Term] id: CL:0017504 name: polychromatophilic cytoplasm def: "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions." [GOC:tfm] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: has_characteristic PATO:0070047 ! polychromatophilic relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_characteristic PATO:0070047 ! polychromatophilic creation_date: 2009-12-28T04:25:23Z [Term] id: CL:0017505 name: increased nucleus size def: "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." [GOC:tfm] is_a: GO:0005634 ! nucleus intersection_of: GO:0005634 ! nucleus intersection_of: has_characteristic PATO:0000586 ! increased size relationship: dc-contributor https://orcid.org/0000-0003-1980-3228 relationship: has_characteristic PATO:0000586 ! increased size creation_date: 2009-12-23T10:53:24Z [Term] id: CL:0019001 name: tracheobronchial serous cell def: "Any serous secreting cell that is part of the tracheobronchial epithelium." [] subset: added_for_HCA synonym: "serous cell of tracheobronchial tree" EXACT [] is_a: CL:0000313 ! serous secreting cell is_a: CL:0000548 ! animal cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: http://purl.org/dc/terms/date "2020-05-07T16:03:27Z" xsd:dateTime [Term] id: CL:0019002 name: tracheobronchial chondrocyte def: "Any chondrocyte that is part of the tracheobronchial tree." [] subset: added_for_HCA subset: human_reference_atlas synonym: "chondrocyte of tracheobronchial tree" EXACT [] is_a: CL:0000138 ! chondrocyte is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000138 ! chondrocyte intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: http://purl.org/dc/terms/date "2020-05-07T17:29:51Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0019018 name: blood vessel smooth muscle cell def: "A smooth muscle cell that is part of any blood vessel." [PMID:9108778] subset: human_reference_atlas synonym: "smooth muscle cell of blood vessel" EXACT [] is_a: CL:0000359 ! vascular associated smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001981 ! blood vessel relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0001981 ! blood vessel property_value: http://purl.org/dc/terms/date "2020-07-21T12:42:48Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0019019 name: tracheobronchial smooth muscle cell def: "A smooth muscle cell that is part of the tracheobronchial tree." [PMID:10853867] subset: human_reference_atlas synonym: "smooth muscle cell of tracheobronchial tree" EXACT [] is_a: CL:0000192 ! smooth muscle cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: http://purl.org/dc/terms/date "2020-07-21T12:50:22Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:0019020 name: extrahepatic cholangiocyte def: "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes." [PMID:23720296] synonym: "large bile duct cholangiocyte" EXACT [PMID:23720296] is_a: CL:1000488 ! cholangiocyte intersection_of: CL:1000488 ! cholangiocyte intersection_of: part_of UBERON:0004822 ! extrahepatic bile duct epithelium relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0004822 ! extrahepatic bile duct epithelium property_value: http://purl.org/dc/terms/date "2020-09-03T12:24:24Z" xsd:dateTime [Term] id: CL:0019021 name: endothelial cell of periportal hepatic sinusoid def: "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid." [PMID:27423426] synonym: "periportal hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "periportal LSEC" EXACT [PMID:28287163] xref: EFO:0010705 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: adjacent_to UBERON:0001279 ! portal triad relationship: adjacent_to UBERON:0001279 ! portal triad relationship: dc-contributor https://orcid.org/0000-0003-2034-601X property_value: http://purl.org/dc/terms/date "2020-09-09T13:56:47Z" xsd:dateTime [Term] id: CL:0019022 name: endothelial cell of pericentral hepatic sinusoid def: "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid." [PMID:27423426] synonym: "central venous hepatic sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "pericentral LSEC" EXACT [PMID:28287163] xref: EFO:0010706 is_a: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: CL:1000398 ! endothelial cell of hepatic sinusoid intersection_of: adjacent_to UBERON:0006841 ! central vein of liver relationship: adjacent_to UBERON:0006841 ! central vein of liver relationship: dc-contributor https://orcid.org/0000-0003-2034-601X property_value: http://purl.org/dc/terms/date "2020-09-10T12:38:29Z" xsd:dateTime [Term] id: CL:1000042 name: forebrain neuroblast is_a: CL:0000031 ! neuroblast (sensu Vertebrata) is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000031 ! neuroblast (sensu Vertebrata) intersection_of: part_of UBERON:0001890 ! forebrain relationship: part_of UBERON:0001890 ! forebrain [Term] id: CL:1000090 name: pronephric nephron tubule epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of UBERON:0005310 ! pronephric nephron tubule [Term] id: CL:1000123 name: metanephric nephron tubule epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0005146 ! metanephric nephron tubule relationship: part_of UBERON:0005146 ! metanephric nephron tubule [Term] id: CL:1000222 name: stomach neuroendocrine cell is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0000165 ! neuroendocrine cell is_a: CL:0002659 ! glandular cell of stomach intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0000945 ! stomach relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: CL:1000223 name: lung neuroendocrine cell subset: human_reference_atlas is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0000165 ! neuroendocrine cell is_a: CL:1000272 ! lung secretory cell intersection_of: CL:0000165 ! neuroendocrine cell intersection_of: part_of UBERON:0002048 ! lung relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000271 name: lung ciliated cell subset: human_reference_atlas is_a: CL:0000548 ! animal cell is_a: CL:4030034 ! respiratory ciliated cell intersection_of: CL:0000064 ! ciliated cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000272 name: lung secretory cell is_a: CL:0000151 ! secretory cell is_a: CL:0000548 ! animal cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000151 ! secretory cell intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: CL:1000274 name: trophectodermal cell synonym: "trophectoderm cell" EXACT [] is_a: CL:0000349 ! extraembryonic cell [Term] id: CL:1000275 name: smooth muscle cell of small intestine def: "A smooth muscle cell that is part of the small intestine." [GOC:tfm] synonym: "non-striated muscle fiber of small intestine" EXACT [FMA:15050] xref: FMA:15050 is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0002108 ! small intestine [Term] id: CL:1000276 name: smooth muscle fiber of duodenum def: "A smooth muscle cell that is part of the duodenum." [GOC:tfm] synonym: "non-striated muscle fiber of duodenum" EXACT [FMA:15058] xref: FMA:15058 is_a: CL:1000275 {is_inferred="true"} ! smooth muscle cell of small intestine intersection_of: CL:1000275 ! smooth muscle cell of small intestine intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum [Term] id: CL:1000279 name: smooth muscle cell of large intestine def: "A smooth muscle cell that is part of the large intestine." [GOC:tfm] subset: human_reference_atlas synonym: "non-striated muscle fiber of large intestine" EXACT [FMA:15653] xref: FMA:15653 is_a: CL:0002504 {is_inferred="true"} ! enteric smooth muscle cell intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0000059 ! large intestine property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000280 name: smooth muscle cell of colon def: "A smooth muscle cell that is part of the colon." [GOC:tfm] synonym: "non-striated muscle fiber of colon" EXACT [FMA:15663] xref: FMA:15663 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0002504 ! enteric smooth muscle cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon [Term] id: CL:1000285 name: smooth muscle cell of sigmoid colon def: "A smooth muscle cell that is part of the sigmoid colon." [GOC:tfm] synonym: "non-striated muscle fiber of sigmoid colon" EXACT [FMA:17521] xref: FMA:17521 is_a: CL:1000280 {is_inferred="true"} ! smooth muscle cell of colon intersection_of: CL:1000280 ! smooth muscle cell of colon intersection_of: part_of UBERON:0001159 ! sigmoid colon relationship: part_of UBERON:0001159 ! sigmoid colon [Term] id: CL:1000286 name: smooth muscle cell of rectum def: "A smooth muscle cell that is part of the rectum." [GOC:tfm] synonym: "non-striated muscle fiber of rectum" EXACT [FMA:17522] synonym: "smooth muscle fiber of rectum" EXACT [] xref: FMA:17522 is_a: CL:1000279 ! smooth muscle cell of large intestine intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: CL:1000296 name: epithelial cell of urethra def: "An epithelial cell that is part of the urethra." [GOC:tfm] xref: FMA:256165 is_a: CL:0000066 {is_inferred="true"} ! epithelial cell is_a: CL:0002371 ! somatic cell is_a: CL:1001320 ! urethra cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000057 ! urethra [Term] id: CL:1000298 name: mesothelial cell of dura mater def: "A mesothelial cell that is part of the dura mater." [GOC:tfm] synonym: "squamous mesothelial cell of dura mater" EXACT [FMA:256516] xref: FMA:256516 is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002363 ! dura mater relationship: part_of UBERON:0002363 ! dura mater [Term] id: CL:1000303 name: fibroblast of areolar connective tissue def: "A fibroblast that is part of the areolar connective tissue." [GOC:tfm] xref: FMA:261279 is_a: CL:0000057 {is_inferred="true"} ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0006815 ! areolar connective tissue relationship: part_of UBERON:0006815 ! areolar connective tissue [Term] id: CL:1000306 name: fibroblast of tunica adventitia of artery def: "A fibroblast that is part of the tunica adventitia of artery." [GOC:tfm] xref: FMA:261285 is_a: CL:0000057 {is_inferred="true"} ! fibroblast is_a: CL:0002503 ! adventitial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005734 ! tunica adventitia of blood vessel relationship: part_of UBERON:0005734 ! tunica adventitia of blood vessel [Term] id: CL:1000307 name: fibroblast of dense regular elastic tissue def: "A fibroblast that is part of the dense regular elastic tissue." [GOC:tfm] xref: FMA:261287 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0007846 ! dense regular connective tissue relationship: part_of UBERON:0002521 ! elastic tissue relationship: part_of UBERON:0007846 ! dense regular connective tissue [Term] id: CL:1000309 name: epicardial adipocyte def: "A fat cell that is part of the epicardial fat." [GOC:tfm] subset: human_reference_atlas synonym: "adipocyte of epicardial fat" EXACT [FMA:261293] synonym: "epicardial fat cell" EXACT [FMA:261293] xref: FMA:261293 is_a: CL:0000136 ! fat cell is_a: CL:0002494 ! cardiocyte is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of UBERON:0002348 ! epicardium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000310 name: adipocyte of epicardial fat of right ventricle def: "A fat cell that is part of the epicardial fat of right ventricle." [GOC:tfm] synonym: "epicardial adipocyte of right ventricle" EXACT [FMA:261297] synonym: "epicardial fat cell of right ventricle" EXACT [FMA:261297] xref: FMA:261297 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0002080 ! heart right ventricle [Term] id: CL:1000311 name: adipocyte of epicardial fat of left ventricle def: "A fat cell that is part of the epicardial fat of left ventricle." [GOC:tfm] synonym: "epicardial adipocyte of left ventricle" EXACT [FMA:261300] synonym: "epicardial fat cell of left ventricle" EXACT [FMA:261300] xref: FMA:261300 is_a: CL:1000309 ! epicardial adipocyte intersection_of: CL:1000309 ! epicardial adipocyte intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 ! heart left ventricle [Term] id: CL:1000330 name: serous cell of epithelium of trachea def: "A serous secreting cell that is part of the epithelium of trachea." [GOC:tfm] subset: human_reference_atlas xref: FMA:263078 is_a: CL:0019001 ! tracheobronchial serous cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:0001901 ! epithelium of trachea relationship: part_of UBERON:0001901 ! epithelium of trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000331 name: serous cell of epithelium of bronchus def: "A serous secreting cell that is part of the epithelium of bronchus." [GOC:tfm] subset: human_reference_atlas xref: FMA:263080 is_a: CL:0019001 ! tracheobronchial serous cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:0002031 ! epithelium of bronchus relationship: part_of UBERON:0002031 ! epithelium of bronchus property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000332 name: serous cell of epithelium of terminal bronchiole def: "A serous secreting cell that is part of the epithelium of terminal bronchiole." [GOC:tfm] xref: FMA:263082 is_a: CL:0019001 ! tracheobronchial serous cell is_a: CL:1000272 ! lung secretory cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:0001958 ! terminal bronchiole epithelium relationship: part_of UBERON:0001958 ! terminal bronchiole epithelium [Term] id: CL:1000361 name: transitional myocyte of interatrial septum def: "A transitional myocyte that is part of the interatrial septum." [GOC:tfm] xref: FMA:263152 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002085 ! interatrial septum relationship: part_of UBERON:0002085 ! interatrial septum [Term] id: CL:1000362 name: transitional myocyte of interventricular septum def: "A transitional myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263154 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000376 name: Purkinje myocyte of interventricular septum def: "A Purkinje myocyte that is part of the interventricular septum." [GOC:tfm] xref: FMA:263182 is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000398 name: endothelial cell of hepatic sinusoid def: "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates." [GOC:tfm, PMID:3926620] subset: human_reference_atlas synonym: "endotheliocyte of hepatic sinusoid" EXACT [FMA:62911] synonym: "liver sinusoidal endothelial cell" EXACT [PMID:30348985] synonym: "LSEC" EXACT [PMID:30348985] xref: BTO:000125 xref: FMA:62911 is_a: CL:0002262 ! endothelial cell of sinusoid is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001281 ! hepatic sinusoid relationship: part_of UBERON:0001281 ! hepatic sinusoid property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000409 name: myocyte of sinoatrial node def: "A muscle cell that is part of the sinoatrial node." [FMA:67102, GOC:tfm] synonym: "myocyte of sinoatrial node" EXACT [FMA:67102] synonym: "SA nodal myocyte" EXACT [FMA:67102] synonym: "SA node cardiac muscle cell" EXACT [GOC:pr] synonym: "sinoatrial node cell" EXACT [GOC:pr] synonym: "sinoatrial node myocyte" EXACT [] synonym: "sinuatrial node myocyte" EXACT [FMA:67102] xref: FMA:67102 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002351 ! sinoatrial node relationship: part_of UBERON:0002351 ! sinoatrial node [Term] id: CL:1000410 name: myocyte of atrioventricular node def: "A muscle cell that is part of the atrioventricular node." [FMA:67106, GOC:tfm] synonym: "atrioventricular node cell" EXACT [GOC:pr] synonym: "atrioventricular node myocyte" EXACT [FMA:67106] synonym: "AV nodal myocyte" EXACT [FMA:67106] synonym: "AV node cardiac muscle cell" EXACT [GOC:pr] synonym: "AV node cell" EXACT [GOC:pr] xref: FMA:67106 is_a: CL:0002072 ! nodal myocyte is_a: CL:0008009 ! transversely striated visceral muscle cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0000187 ! muscle cell intersection_of: part_of UBERON:0002352 ! atrioventricular node relationship: part_of UBERON:0002352 ! atrioventricular node [Term] id: CL:1000412 name: endothelial cell of arteriole def: "An endothelial cell that is part of the arteriole." [GOC:tfm] subset: human_reference_atlas xref: FMA:67760 xref: KUPO:0001097 is_a: CL:0000071 {is_inferred="true"} ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001980 ! arteriole relationship: part_of UBERON:0001980 ! arteriole property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000413 name: endothelial cell of artery def: "A blood vessel endothelial cell that is part of an arterial endothelium." [GOC:tfm] subset: human_reference_atlas synonym: "arterial endothelial cell" EXACT [] xref: BTO:0004758 xref: FMA:67761 xref: KUPO:0001095 is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0001917 ! endothelium of artery property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000414 name: endothelial cell of venule def: "An endothelial cell that is part of the venule." [GOC:tfm] subset: human_reference_atlas xref: FMA:67762 is_a: CL:0002139 {is_inferred="true"} ! endothelial cell of vascular tree intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0001979 ! venule relationship: part_of UBERON:0001979 ! venule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000415 name: epithelial cell of gallbladder def: "An epithelial cell that is part of the gallbladder." [GOC:tfm] xref: FMA:67780 is_a: CL:0000066 {is_inferred="true"} ! epithelial cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: CL:1000428 name: stem cell of epidermis def: "A somatic stem cell that is part of the epidermis." [GOC:tfm] synonym: "epidermal stem cell" EXACT [FMA:70541] xref: FMA:70541 is_a: CL:0000723 {is_inferred="true"} ! somatic stem cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000723 ! somatic stem cell intersection_of: part_of UBERON:0001003 ! skin epidermis relationship: part_of UBERON:0001003 ! skin epidermis [Term] id: CL:1000434 name: epithelial cell of external acoustic meatus def: "An epithelial cell that is part of the external acoustic meatus." [GOC:tfm] xref: FMA:70555 is_a: CL:0000066 {is_inferred="true"} ! epithelial cell is_a: CL:0002371 ! somatic cell is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001352 ! external acoustic meatus relationship: part_of UBERON:0001352 ! external acoustic meatus [Term] id: CL:1000443 name: ciliary muscle cell def: "A smooth muscle cell that is part of the ciliary body." [GOC:tfm] subset: eye_upper_slim synonym: "smooth muscle cell of ciliary body" EXACT [FMA:70610] xref: FMA:70610 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0001775 ! ciliary body relationship: part_of UBERON:0001775 ! ciliary body [Term] id: CL:1000444 name: mesothelial cell of anterior chamber of eye def: "A mesothelial cell that is part of the anterior chamber of eyeball." [GOC:tfm] xref: FMA:70615 is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001766 ! anterior chamber of eyeball relationship: part_of UBERON:0001766 ! anterior chamber of eyeball [Term] id: CL:1000449 name: epithelial cell of nephron def: "An epithelial cell that is part of the nephron." [GOC:tfm] xref: FMA:70965 is_a: CL:0002518 ! kidney epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001285 ! nephron relationship: part_of UBERON:0001285 ! nephron [Term] id: CL:1000454 name: kidney collecting duct epithelial cell def: "An epithelial cell that is part of the collecting duct of renal tubule." [GOC:tfm] subset: human_reference_atlas synonym: "epithelial cell of renal collecting tubule" EXACT [FMA:70982] xref: FMA:70982 xref: KUPO:0001059 is_a: CL:0000072 {is_inferred="true"} ! non-branched duct epithelial cell is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1001225 {is_inferred="true"} ! kidney collecting duct cell intersection_of: CL:0000072 ! non-branched duct epithelial cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000456 name: mesothelial cell of parietal peritoneum def: "A mesothelial cell that is part of the parietal peritoneum." [GOC:tfm] xref: FMA:72142 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001366 ! parietal peritoneum relationship: part_of UBERON:0001366 ! parietal peritoneum [Term] id: CL:1000457 name: mesothelial cell of visceral peritoneum def: "A mesothelial cell that is part of the visceral peritoneum." [GOC:tfm] subset: human_reference_atlas xref: FMA:72143 is_a: CL:1000490 ! mesothelial cell of peritoneum intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0001178 ! visceral peritoneum relationship: part_of UBERON:0001178 ! visceral peritoneum property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000478 name: transitional myocyte of sinoatrial node def: "A transitional myocyte that is part of the sinoatrial node." [GOC:tfm] synonym: "transitinal myocyte of sinuatrial node" EXACT [] xref: FMA:83384 is_a: CL:0002073 {is_inferred="true"} ! transitional myocyte is_a: CL:1000409 ! myocyte of sinoatrial node intersection_of: CL:0002073 ! transitional myocyte intersection_of: part_of UBERON:0002351 ! sinoatrial node [Term] id: CL:1000479 name: Purkinje myocyte of atrioventricular node def: "A Purkinje myocyte that is part of the atrioventricular node." [GOC:tfm] xref: FMA:83386 is_a: CL:0002068 {is_inferred="true"} ! Purkinje myocyte is_a: CL:1000410 ! myocyte of atrioventricular node intersection_of: CL:0002068 ! Purkinje myocyte intersection_of: part_of UBERON:0002352 ! atrioventricular node [Term] id: CL:1000482 name: myocardial endocrine cell of interventricular septum def: "A myocardial endocrine cell that is part of the interventricular septum." [GOC:tfm] xref: FMA:83390 is_a: CL:0002074 {is_inferred="true"} ! myocardial endocrine cell is_a: CL:2000022 ! cardiac septum cell intersection_of: CL:0002074 ! myocardial endocrine cell intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum [Term] id: CL:1000488 name: cholangiocyte def: "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." [GOC:tfm, PMID:16550043, PMID:18356246] synonym: "epithelial cell of bile duct" EXACT [] xref: FMA:86481 is_a: CL:0000069 {is_inferred="true"} ! branched duct epithelial cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000069 ! branched duct epithelial cell intersection_of: capable_of GO:0015106 ! bicarbonate transmembrane transporter activity intersection_of: part_of UBERON:0002394 ! bile duct relationship: develops_from CL:0005026 ! hepatoblast relationship: part_of UBERON:0002394 ! bile duct [Term] id: CL:1000490 name: mesothelial cell of peritoneum def: "A mesothelial cell that is part of the peritoneum." [GOC:tfm] synonym: "peritoneal mesothelial cell" EXACT [FMA:86736] xref: FMA:86736 is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002358 ! peritoneum relationship: part_of UBERON:0002358 ! peritoneum [Term] id: CL:1000491 name: mesothelial cell of pleura def: "A mesothelial cell that is part of the pleura." [GOC:tfm] synonym: "pleural mesothelial cell" EXACT [FMA:86737] xref: FMA:86737 is_a: CL:0000077 {is_inferred="true"} ! mesothelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0000977 ! pleura relationship: part_of UBERON:0000977 ! pleura [Term] id: CL:1000492 name: mesothelial cell of parietal pleura def: "A mesothelial cell that is part of the parietal pleura." [GOC:tfm] xref: FMA:86738 is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002400 ! parietal pleura relationship: part_of UBERON:0002400 ! parietal pleura [Term] id: CL:1000493 name: mesothelial cell of visceral pleura def: "A mesothelial cell that is part of the visceral pleura." [GOC:tfm] subset: human_reference_atlas xref: FMA:86739 is_a: CL:0000082 ! epithelial cell of lung is_a: CL:1000491 ! mesothelial cell of pleura intersection_of: CL:0000077 ! mesothelial cell intersection_of: part_of UBERON:0002401 ! visceral pleura relationship: part_of UBERON:0002401 ! visceral pleura property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000494 name: nephron tubule epithelial cell def: "An epithelial cell that is part of a nephron tubule." [GOC:tfm] comment: This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON. synonym: "kidney tubule epithelial cell" EXACT [] xref: FMA:86785 xref: KUPO:0001022 is_a: CL:1000449 ! epithelial cell of nephron is_a: CL:1000507 ! kidney tubule cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004810 ! nephron tubule epithelium relationship: part_of UBERON:0004810 ! nephron tubule epithelium [Term] id: CL:1000497 name: kidney cell xref: KUPO:0001010 is_a: CARO:0000000 ! anatomical entity is_a: CL:0002371 ! somatic cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney [Term] id: CL:1000500 name: kidney interstitial cell xref: KUPO:0001013 is_a: CL:1000497 {is_inferred="true"} ! kidney cell is_a: CL:4030031 ! interstitial cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0005215 ! kidney interstitium relationship: part_of UBERON:0005215 ! kidney interstitium [Term] id: CL:1000505 name: kidney pelvis cell xref: KUPO:0001018 is_a: CL:1000497 {is_inferred="true"} ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: CL:1000507 name: kidney tubule cell xref: KUPO:0001020 is_a: CL:1000497 {is_inferred="true"} ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0001231 ! nephron tubule [Term] id: CL:1000549 name: kidney cortex collecting duct epithelial cell xref: KUPO:0001063 is_a: CL:0002681 ! kidney cortical cell is_a: CL:1001225 ! kidney collecting duct cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0004203 ! cortical collecting duct relationship: part_of UBERON:0004203 ! cortical collecting duct [Term] id: CL:1000600 name: lower urinary tract cell xref: KUPO:0001115 is_a: CL:0000548 {is_inferred="true"} ! animal cell intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0001556 ! lower urinary tract relationship: part_of UBERON:0001556 ! lower urinary tract [Term] id: CL:1000601 name: ureteral cell xref: KUPO:0001116 is_a: CL:0000548 {is_inferred="true"} ! animal cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0000056 ! ureter [Term] id: CL:1000606 name: kidney nerve cell xref: KUPO:0001015 is_a: CL:1000500 ! kidney interstitial cell is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0002113 ! kidney relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0002113 ! kidney [Term] id: CL:1000681 name: kidney cortex interstitial cell xref: KUPO:0001091 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000500 {is_inferred="true"} ! kidney interstitial cell intersection_of: CL:1000500 ! kidney interstitial cell intersection_of: part_of UBERON:0005270 ! renal cortex interstitium relationship: part_of UBERON:0005270 ! renal cortex interstitium [Term] id: CL:1000692 name: kidney interstitial fibroblast subset: human_reference_atlas xref: KUPO:0001102 is_a: CL:0000057 ! fibroblast is_a: CL:1000500 ! kidney interstitial cell intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005215 ! kidney interstitium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000702 name: kidney pelvis smooth muscle cell xref: KUPO:0001113 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1000505 {is_inferred="true"} ! kidney pelvis cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0004227 ! kidney pelvis smooth muscle relationship: part_of UBERON:0004227 ! kidney pelvis smooth muscle [Term] id: CL:1000708 name: ureter adventitial cell subset: human_reference_atlas xref: KUPO:0001119 is_a: CL:0000115 ! endothelial cell is_a: CL:0002503 ! adventitial cell is_a: CL:1000601 {is_inferred="true"} ! ureteral cell intersection_of: CL:1000601 ! ureteral cell intersection_of: part_of UBERON:0001252 ! adventitia of ureter relationship: part_of UBERON:0001252 ! adventitia of ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000714 name: kidney cortex collecting duct principal cell subset: human_reference_atlas xref: KUPO:0001130 is_a: CL:0002584 ! renal cortical epithelial cell is_a: CL:1000549 {is_inferred="true"} ! kidney cortex collecting duct epithelial cell is_a: CL:1001431 ! kidney collecting duct principal cell intersection_of: CL:0005009 ! renal principal cell intersection_of: part_of UBERON:0004203 ! cortical collecting duct property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1000979 name: ureter smooth muscle cell xref: KUPO:0001118 is_a: CL:0000192 {is_inferred="true"} ! smooth muscle cell is_a: CL:1000601 {is_inferred="true"} ! ureteral cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0006855 ! muscular coat of ureter relationship: part_of UBERON:0006855 ! muscular coat of ureter [Term] id: CL:1001225 name: kidney collecting duct cell xref: KUPO:0001012 xref: Wikipedia:Kidney_collecting_duct_cell is_a: CL:1000497 {is_inferred="true"} ! kidney cell intersection_of: CL:1000497 ! kidney cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0001232 ! collecting duct of renal tubule [Term] id: CL:1001319 name: bladder cell subset: human_reference_atlas xref: KUPO:0001120 is_a: CL:1000600 ! lower urinary tract cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 ! urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001320 name: urethra cell xref: KUPO:0001123 is_a: CL:1000600 ! lower urinary tract cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000548 ! animal cell intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: CL:1001431 name: kidney collecting duct principal cell subset: human_reference_atlas xref: KUPO:0001128 is_a: CL:0005009 {is_inferred="true"} ! renal principal cell is_a: CL:1000454 ! kidney collecting duct epithelial cell intersection_of: CL:0005009 ! renal principal cell intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001433 name: epithelial cell of exocrine pancreas def: "An epithelial cell of the exocrine pancreas." [GOC:tfm] subset: human_reference_atlas synonym: "exocrine pancreas cell" EXACT [] xref: FMA:70986 is_a: CL:0000083 ! epithelial cell of pancreas intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0000017 ! exocrine pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001516 name: intestinal enteroendocrine cell def: "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract." [MP:0010802] is_a: CL:0000164 ! enteroendocrine cell is_a: CL:0002563 ! intestinal epithelial cell intersection_of: CL:0000164 ! enteroendocrine cell intersection_of: part_of UBERON:0001242 ! intestinal mucosa [Term] id: CL:1001567 name: lung endothelial cell subset: human_reference_atlas synonym: "endothelial cell of lung" RELATED [] synonym: "pulmonary vessel endothelial cell" RELATED [] is_a: CL:0000082 ! epithelial cell of lung is_a: CL:0002139 ! endothelial cell of vascular tree is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0000102 ! lung vasculature property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001568 name: pulmonary artery endothelial cell subset: human_reference_atlas synonym: "PAEC cell" RELATED [BTO:0001141] xref: BTO:0001141 is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:0002139 ! endothelial cell of vascular tree intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: part_of UBERON:0005317 ! pulmonary artery endothelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001572 name: colon endothelial cell def: "A vascular endothelial cell found in colon blood vessels." [https://orcid.org/0000-0001-5208-3432, NPX:PDR] synonym: "colon endothelial cells" RELATED PLURAL [CALOHA:TS-2397] synonym: "colonic endothelial cell" RELATED [CALOHA:TS-2397] xref: CALOHA:TS-2397 is_a: CL:0000115 ! endothelial cell is_a: CL:0011108 ! colon epithelial cell is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0013695 ! colon endothelium [Term] id: CL:1001573 name: nasopharyngeal epithelial cell def: "Cell of the nasopharyngeal epithelium." [NPX:PDR] synonym: "nasopharynx respiratory epithelial cells" RELATED [CALOHA:TS-2398] xref: CALOHA:TS-2398 is_a: CL:0002251 ! epithelial cell of alimentary canal is_a: CL:0002631 ! epithelial cell of upper respiratory tract intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001951 ! epithelium of nasopharynx [Term] id: CL:1001576 name: oral mucosa squamous cell def: "Squamous cell of oral epithelium." [NPX:PDR] synonym: "oral cavity mucosa squamous cell" RELATED [CALOHA:TS-1252] synonym: "oral cavity mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252] synonym: "oral mucosa squamous epithelial cell" RELATED [CALOHA:TS-1252] synonym: "oral mucosa squamous epithelial cells" RELATED [CALOHA:TS-1252] xref: CALOHA:TS-1252 is_a: CL:0000076 ! squamous epithelial cell is_a: CL:0002251 ! epithelial cell of alimentary canal intersection_of: CL:0000076 ! squamous epithelial cell intersection_of: part_of UBERON:0002424 ! oral epithelium relationship: part_of UBERON:0002424 ! oral epithelium [Term] id: CL:1001579 name: cerebral cortex glial cell def: "Glial cell of cerebral cortex." [NPX:PDR] synonym: "brain cortex glial cell" RELATED [CALOHA:TS-1256] synonym: "cerebral cortex glial cells" RELATED [CALOHA:TS-1256] synonym: "cerebrum cortex glial cell" RELATED [CALOHA:TS-1256] xref: CALOHA:TS-1256 is_a: CL:0000125 ! glial cell intersection_of: CL:0000125 ! glial cell intersection_of: part_of UBERON:0000956 ! cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex [Term] id: CL:1001588 name: colon glandular cell def: "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] synonym: "colon glandular cells" RELATED [CALOHA:TS-1274] xref: CALOHA:TS-1274 is_a: CL:0002658 ! glandular cell of the large intestine is_a: CL:0011108 ! colon epithelial cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001155 ! colon [Term] id: CL:1001589 name: duodenum glandular cell def: "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell." [NPX:PDR] synonym: "duodenum glandular cells" RELATED [CALOHA:TS-1275] xref: CALOHA:TS-1275 is_a: CL:1001598 ! small intestine glandular cell intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0008346 ! duodenal epithelium [Term] id: CL:1001590 name: epididymis glandular cell def: "Glandular cell of epididymal epithelium." [NPX:PDR] synonym: "epididymal glandular cell" RELATED [CALOHA:TS-1276] synonym: "epididymis glandular cells" RELATED [CALOHA:TS-1276] xref: CALOHA:TS-1276 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0004544 ! epididymis epithelium [Term] id: CL:1001591 name: oviduct glandular cell def: "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." [HPA:HPA, NPX:PDR] synonym: "fallopian tube glandular cell" RELATED [CALOHA:TS-1277] synonym: "fallopian tube glandular cells" RELATED [CALOHA:TS-1277] synonym: "uterine tube glandular cell" RELATED [CALOHA:TS-1277] xref: CALOHA:TS-1277 is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000993 ! oviduct relationship: part_of UBERON:0004804 ! oviduct epithelium [Term] id: CL:1001592 name: gallbladder glandular cell def: "Glandular cell of gallbladder epithelium." [NPX:PDR] synonym: "gall bladder glandular cell" EXACT [FMA:7202] synonym: "gall bladder glandular cells" RELATED [CALOHA:TS-1278] synonym: "gallbladder glandular cells" RELATED [CALOHA:TS-1278] xref: CALOHA:TS-1278 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:1000415 ! epithelial cell of gallbladder intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002029 ! epithelium of gall bladder [Term] id: CL:1001595 name: rectum glandular cell def: "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells." [NPX:PDR] synonym: "rectal glandular cell" RELATED [CALOHA:TS-1281] synonym: "rectum glandular cells" RELATED [CALOHA:TS-1281] xref: CALOHA:TS-1281 is_a: CL:0002658 ! glandular cell of the large intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0003354 ! epithelium of rectum [Term] id: CL:1001597 name: seminal vesicle glandular cell def: "Glandular cell of seminal vesicle epithelium." [NPX:PDR] synonym: "seminal vesicle glandular cells" RELATED [CALOHA:TS-1283] xref: CALOHA:TS-1283 is_a: CL:0000068 ! duct epithelial cell is_a: CL:0000150 ! glandular epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: part_of UBERON:0004805 ! seminal vesicle epithelium [Term] id: CL:1001598 name: small intestine glandular cell def: "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." [NCI_Thesaurus:Small_Intestinal_Glandular_Cell, NPX:PDR] synonym: "small bowel glandular cell" RELATED [CALOHA:TS-1286] synonym: "small intestinal glandular cell" RELATED [CALOHA:TS-1286] synonym: "small intestine glandular cells" RELATED [CALOHA:TS-1286] xref: CALOHA:TS-1286 xref: FMA:86928 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0002254 ! epithelial cell of small intestine intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001902 ! epithelium of small intestine [Term] id: CL:1001599 name: pancreas exocrine glandular cell def: "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." [HPA:HPA, NPX:PDR] subset: human_reference_atlas synonym: "exocrine pancreas glandular cell" RELATED [CALOHA:TS-1242] synonym: "pancreas exocrine glandular cells" RELATED [CALOHA:TS-1242] xref: BTO:0000028 xref: CALOHA:TS-1242 is_a: CL:0000150 ! glandular epithelial cell is_a: CL:0000152 ! exocrine cell is_a: CL:1001433 ! epithelial cell of exocrine pancreas intersection_of: CL:0000150 ! glandular epithelial cell intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0013697 ! exocrine pancreas epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:1001602 name: cerebral cortex endothelial cell def: "Endothelial cells forming the walls of the capillaries within the cerebral cortex." [NPX:PDR] synonym: "cerebral cortex endothelial cells" RELATED [CALOHA:TS-2372] synonym: "endothelial cells of cerebral cortex" RELATED [CALOHA:TS-2372] xref: CALOHA:TS-2372 is_a: CL:0000115 ! endothelial cell is_a: CL:0002319 ! neural cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0000956 ! cerebral cortex relationship: part_of UBERON:0000956 ! cerebral cortex relationship: part_of UBERON:0013694 ! brain endothelium [Term] id: CL:1001609 name: muscle fibroblast def: "Fibroblast from muscle organ." [NPX:PDR] xref: CALOHA:TS-0643 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001630 ! muscle organ relationship: part_of UBERON:0001630 ! muscle organ [Term] id: CL:1001610 name: bone marrow hematopoietic cell def: "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes." [NPX:PDR] synonym: "bone marrow hematopoietic cells" RELATED [CALOHA:TS-2109] synonym: "bone marrow poietic cells" RELATED [CALOHA:TS-2109] xref: CALOHA:TS-2109 is_a: CL:0000988 ! hematopoietic cell is_a: CL:0002092 ! bone marrow cell intersection_of: CL:0000988 ! hematopoietic cell intersection_of: part_of UBERON:0002371 ! bone marrow relationship: part_of UBERON:0012429 ! hematopoietic tissue [Term] id: CL:2000001 name: peripheral blood mononuclear cell def: "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." [GOC:TermGenie] is_a: CL:0000080 ! circulating cell is_a: CL:0000842 ! mononuclear cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000842 ! mononuclear cell intersection_of: part_of UBERON:0000178 ! blood relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000178 ! blood creation_date: 2014-02-11T17:29:04Z [Term] id: CL:2000002 name: decidual cell def: "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization." [BTO:0002770, NCIT:C32429, PMID:30013421, PMID:30429548, Wiki:Decidual_cells&oldid=937509751, Wiki:Decidualization&oldid=908981933] synonym: "decidua cell" EXACT [BTO:0002770, NCIT:C32429] synonym: "decidual stromal cell" EXACT [BTO:0005756, PMID:11719592] xref: BTO:0002770 xref: BTO:0005756 xref: NCIT:C32429 is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000499 ! stromal cell is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from CL:0002255 ! stromal cell of endometrium relationship: part_of UBERON:0002450 ! decidua creation_date: 2014-02-20T23:06:41Z [Term] id: CL:2000005 name: brain macroglial cell def: "Any macroglial cell that is part of a brain." [GOC:TermGenie] is_a: CL:0000126 ! macroglial cell intersection_of: CL:0000126 ! macroglial cell intersection_of: part_of UBERON:0000955 ! brain relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000955 ! brain creation_date: 2014-03-28T21:35:27Z [Term] id: CL:2000008 name: microvascular endothelial cell def: "Any blood vessel endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] subset: human_reference_atlas is_a: CL:0000071 ! blood vessel endothelial cell intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0008339 ! microvascular endothelium relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0008339 ! microvascular endothelium property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-06-04T15:07:42Z [Term] id: CL:2000010 name: dermis blood vessel endothelial cell def: "Any blood vessel endothelial cell that is part of a dermis." [GOC:TermGenie] is_a: CL:0000071 ! blood vessel endothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000071 ! blood vessel endothelial cell intersection_of: part_of UBERON:0002067 ! dermis relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002067 ! dermis creation_date: 2014-06-04T15:12:06Z [Term] id: CL:2000012 name: fibroblast of pedal digit skin def: "Any skin fibroblast that is part of a pedal digit skin." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0003530 ! pedal digit skin relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0003530 ! pedal digit skin creation_date: 2014-06-04T15:16:44Z [Term] id: CL:2000013 name: fibroblast of skin of abdomen def: "Any skin fibroblast that is part of a skin of abdomen." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0001416 ! skin of abdomen relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001416 ! skin of abdomen creation_date: 2014-06-04T15:18:16Z [Term] id: CL:2000014 name: fibroblast of upper leg skin def: "Any skin fibroblast that is part of a upper leg skin." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0004262 ! upper leg skin relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0004262 ! upper leg skin creation_date: 2014-06-04T15:19:44Z [Term] id: CL:2000015 name: fibroblast of arm def: "Any skin fibroblast that is part of a arm." [GOC:TermGenie] is_a: CL:0002620 ! skin fibroblast intersection_of: CL:0002620 ! skin fibroblast intersection_of: part_of UBERON:0001460 ! arm relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001460 ! arm creation_date: 2014-06-04T15:29:06Z [Term] id: CL:2000016 name: lung microvascular endothelial cell def: "Any lung endothelial cell that is part of a microvascular endothelium." [GOC:TermGenie] is_a: CL:1001567 ! lung endothelial cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:1001567 ! lung endothelial cell intersection_of: part_of UBERON:0008339 ! microvascular endothelium relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 creation_date: 2014-06-04T16:00:56Z [Term] id: CL:2000017 name: fibroblast of peridontal ligament def: "Any fibroblast that is part of a periodontal ligament." [GOC:TermGenie] is_a: CL:0002556 ! fibroblast of periodontium is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0008266 ! periodontal ligament relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0008266 ! periodontal ligament creation_date: 2014-06-04T16:50:33Z [Term] id: CL:2000019 name: compound eye photoreceptor cell def: "Any photoreceptor cell that is part of a compound eye." [GOC:TermGenie] xref: FBbt:00004211 is_a: CL:0000287 ! eye photoreceptor cell intersection_of: CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000018 ! compound eye relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000018 ! compound eye creation_date: 2014-06-24T23:16:45Z [Term] id: CL:2000020 name: inner cell mass cell def: "Any native cell that is part of a inner cell mass." [GOC:TermGenie] is_a: CARO:0000000 ! anatomical entity is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0000087 ! inner cell mass relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000087 ! inner cell mass creation_date: 2014-06-24T23:16:53Z [Term] id: CL:2000022 name: cardiac septum cell def: "Any native cell that is part of a cardiac septum." [GOC:TermGenie] is_a: CL:0000548 ! animal cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0002099 ! cardiac septum relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002099 ! cardiac septum creation_date: 2014-06-24T23:17:07Z [Term] id: CL:2000025 name: spinal cord oligodendrocyte def: "Any oligodendrocyte that is part of a spinal cord." [GOC:TermGenie] is_a: CL:0000128 ! oligodendrocyte intersection_of: CL:0000128 ! oligodendrocyte intersection_of: part_of UBERON:0002240 ! spinal cord relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002240 ! spinal cord creation_date: 2014-06-25T00:23:50Z [Term] id: CL:2000029 name: central nervous system neuron def: "Any neuron that is part of a central nervous system." [GOC:TermGenie] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0001017 ! central nervous system relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: has_soma_location UBERON:0001017 ! central nervous system creation_date: 2014-06-25T01:17:43Z [Term] id: CL:2000032 name: peripheral nervous system neuron def: "A neuron that is part of a peripheral nervous system." [GOC:TermGenie, ISBN:0721662544] synonym: "peripheral neuron" EXACT [] synonym: "PNS neuron" EXACT [] xref: FMA:84664 is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: has_soma_location UBERON:0000010 ! peripheral nervous system relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: has_soma_location UBERON:0000010 ! peripheral nervous system creation_date: 2014-06-25T02:28:17Z [Term] id: CL:2000040 name: bladder microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a urinary bladder." [GOC:TermGenie] subset: human_reference_atlas is_a: CL:1001319 ! bladder cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-07-09T00:04:47Z [Term] id: CL:2000042 name: embryonic fibroblast def: "Any fibroblast that is part of a embryo." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000922 ! embryo relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000922 ! embryo creation_date: 2014-07-09T00:12:00Z [Term] id: CL:2000044 name: brain microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a brain." [GOC:TermGenie] is_a: CL:0002319 ! neural cell is_a: CL:2000008 ! microvascular endothelial cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0000955 ! brain relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000955 ! brain creation_date: 2014-07-09T00:24:53Z [Term] id: CL:2000046 name: ventricular cardiac muscle cell def: "Any cardiac muscle cell that is part of a cardiac ventricle." [GOC:TermGenie] is_a: CL:0000746 ! cardiac muscle cell intersection_of: CL:0000746 ! cardiac muscle cell intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002082 ! cardiac ventricle creation_date: 2014-08-12T20:50:28Z [Term] id: CL:2000047 name: brainstem motor neuron def: "Any motor neuron that is part of a brainstem." [GOC:TermGenie] is_a: CL:0000100 ! motor neuron is_a: CL:2000029 ! central nervous system neuron intersection_of: CL:0000100 ! motor neuron intersection_of: has_soma_location UBERON:0002298 ! brainstem relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_soma_location UBERON:0002298 ! brainstem creation_date: 2014-10-02T23:52:53Z [Term] id: CL:2000051 name: splenic fibroblast def: "Any fibroblast that is part of a spleen." [GOC:TermGenie] is_a: CL:0000057 ! fibroblast is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002106 ! spleen relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002106 ! spleen creation_date: 2014-10-06T18:58:47Z [Term] id: CL:2000052 name: umbilical artery endothelial cell def: "Any endothelial cell of artery that is part of a umbilical cord." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=8010 is_a: CL:0000349 ! extraembryonic cell is_a: CL:1000413 ! endothelial cell of artery intersection_of: CL:1000413 ! endothelial cell of artery intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002331 ! umbilical cord creation_date: 2014-10-06T19:01:48Z [Term] id: CL:2000053 name: splenic endothelial cell def: "Any endothelial cell that is part of a spleen." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5500 subset: human_reference_atlas is_a: CL:0000115 ! endothelial cell intersection_of: CL:0000115 ! endothelial cell intersection_of: part_of UBERON:0002106 ! spleen relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002106 ! spleen property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-06T19:06:04Z [Term] id: CL:2000055 name: liver dendritic cell def: "Any dendritic cell that is part of a liver." [GOC:TermGenie] comment: http://www.jleukbio.org/content/66/2/322.abstract synonym: "hepatic dendritic cell" EXACT [] is_a: CL:0000451 ! dendritic cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000451 ! dendritic cell intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002107 ! liver creation_date: 2014-10-06T19:16:11Z [Term] id: CL:2000060 name: placental villous trophoblast def: "A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua." [PMID:31049600] comment: Same as synctial trophoblast? synonym: "vCTB" EXACT [PMID:31049600] synonym: "villous cytotrophoblast" EXACT [] xref: BTO:0006119 xref: BTO:0006208 is_a: CL:0000351 ! trophoblast cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000351 ! trophoblast cell intersection_of: part_of UBERON:0010005 ! placental labyrinth villous relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0010005 ! placental labyrinth villous property_value: seeAlso "http://www.sciencellonline.com/site/productInformation.php?keyword=7120" xsd:string creation_date: 2014-10-07T17:48:27Z [Term] id: CL:2000061 name: placental amniotic mesenchymal stromal cell def: "Any mesenchymal stem cell that is part of a placenta." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7140 is_a: CL:0000134 ! mesenchymal stem cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000134 ! mesenchymal stem cell intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001987 ! placenta creation_date: 2014-10-07T17:51:11Z [Term] id: CL:2000062 name: placental villus capillary endothelial cell def: "Any capillary endothelial cell that is part of a placenta." [GOC:TermGenie] comment: http://www.ncbi.nlm.nih.gov/books/NBK53245/ subset: human_reference_atlas is_a: CL:0002144 ! capillary endothelial cell is_a: CL:0009092 ! endothelial cell of placenta intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0010005 ! placental labyrinth villous relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0010005 ! placental labyrinth villous property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-07T17:55:56Z [Term] id: CL:2000063 name: ovarian fibroblast def: "Any fibroblast that is part of a female gonad." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7330 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0000992 ! ovary relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000992 ! ovary creation_date: 2014-10-07T17:57:42Z [Term] id: CL:2000064 name: ovarian surface epithelial cell def: "Any epithelial cell that is part of a female gonad." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7310 is_a: CARO:0000000 ! anatomical entity is_a: CL:0000066 ! epithelial cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0000992 ! ovary relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000992 ! ovary creation_date: 2014-10-07T17:59:13Z [Term] id: CL:2000065 name: ovarian microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a female urethra." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7300 is_a: CL:1000296 ! epithelial cell of urethra is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001334 ! female urethra relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001334 ! female urethra creation_date: 2014-10-07T18:18:01Z [Term] id: CL:2000066 name: cardiac ventricle fibroblast def: "Any fibroblast that is part of a cardiac ventricle." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6310 subset: human_reference_atlas is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-07T18:35:38Z [Term] id: CL:2000067 name: cardiac atrium fibroblast def: "Any fibroblast that is part of a cardiac atrium." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6320 subset: human_reference_atlas is_a: CL:0002548 ! fibroblast of cardiac tissue intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002081 ! cardiac atrium property_value: RO:0002175 NCBITaxon:9606 creation_date: 2014-10-07T18:36:54Z [Term] id: CL:2000068 name: pericardium fibroblast def: "Any fibroblast that is part of a pericardium." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6430 is_a: CL:0000057 ! fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002407 ! pericardium relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002407 ! pericardium creation_date: 2014-10-07T18:38:06Z [Term] id: CL:2000069 name: gallbladder fibroblast def: "Any fibroblast that is part of a gallbladder." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=5430 is_a: CL:0000057 ! fibroblast is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0002110 ! gallbladder relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002110 ! gallbladder creation_date: 2014-10-07T18:41:43Z [Term] id: CL:2000070 name: optic choroid fibroblast def: "Any fibroblast that is part of a optic choroid." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=6620 is_a: CL:0000057 ! fibroblast is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0001776 ! optic choroid relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001776 ! optic choroid creation_date: 2014-10-07T18:50:43Z [Term] id: CL:2000072 name: adipose microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a adipose tissue." [GOC:TermGenie] comment: http://www.sciencellonline.com/site/productInformation.php?keyword=7200 is_a: CL:0002320 ! connective tissue cell is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0001013 ! adipose tissue relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0001013 ! adipose tissue creation_date: 2014-10-07T22:13:45Z [Term] id: CL:2000073 name: migratory cardiac neural crest cell def: "Any migratory neural crest cell that is part of a cardiac neural crest." [GOC:TermGenie] synonym: "cardiac neural crest cell" EXACT [PMID:33060096] is_a: CL:0000333 ! migratory neural crest cell intersection_of: CL:0000333 ! migratory neural crest cell intersection_of: part_of UBERON:0000095 ! cardiac neural crest relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000095 ! cardiac neural crest creation_date: 2014-11-05T01:18:43Z [Term] id: CL:2000074 name: splenocyte def: "Any leukocyte that is part of a spleen." [GOC:TermGenie] comment: Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology. is_a: CL:0000738 ! leukocyte is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000738 ! leukocyte intersection_of: part_of UBERON:0002106 ! spleen relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002106 ! spleen creation_date: 2014-11-05T01:26:50Z [Term] id: CL:2000076 name: hindlimb stylopod vein endothelial cell def: "Any vein endothelial cell that is part of a hindlimb stylopod." [GOC:TermGenie] is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0002543 ! vein endothelial cell intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000376 ! hindlimb stylopod creation_date: 2014-12-02T18:40:47Z [Term] id: CL:2000079 name: mesenchymal stem cell of femoral bone marrow def: "Any mesenchymal stem cell of the bone marrow that is part of a femur." [GOC:TermGenie] is_a: CL:0002540 ! mesenchymal stem cell of the bone marrow intersection_of: CL:0002540 ! mesenchymal stem cell of the bone marrow intersection_of: part_of UBERON:0000981 ! femur relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000981 ! femur creation_date: 2014-12-02T19:07:31Z [Term] id: CL:2000080 name: mesenchymal stem cell of abdominal adipose tissue def: "Any mesenchymal stem cell of adipose tissue that is part of an abdomen." [GOC:TermGenie] synonym: "mesenchymal stem cell of abdominal adipose" EXACT [] is_a: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: CL:0002570 ! mesenchymal stem cell of adipose tissue intersection_of: part_of UBERON:0000916 ! abdomen relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0000916 ! abdomen creation_date: 2014-12-02T19:10:34Z [Term] id: CL:2000085 name: mononuclear cell of umbilical cord def: "Any mononuclear cell that is part of a umbilical cord." [GOC:TermGenie] is_a: CL:0000349 ! extraembryonic cell is_a: CL:0000842 ! mononuclear cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000842 ! mononuclear cell intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002331 ! umbilical cord creation_date: 2014-12-02T20:14:16Z [Term] id: CL:2000091 name: endometrial microvascular endothelial cell def: "Any microvascular endothelial cell that is part of a endometrial blood vessel." [GOC:TermGenie] subset: human_reference_atlas is_a: CL:0009095 ! endothelial cell of uterus is_a: CL:2000008 ! microvascular endothelial cell intersection_of: CL:2000008 ! microvascular endothelial cell intersection_of: part_of UBERON:0015172 ! endometrial blood vessel relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0015172 ! endometrial blood vessel property_value: RO:0002175 NCBITaxon:9606 creation_date: 2015-03-31T21:02:36Z [Term] id: CL:2000093 name: bronchus fibroblast of lung def: "Any fibroblast of lung that is part of a bronchus." [GOC:TermGenie] is_a: CL:0002553 ! fibroblast of lung intersection_of: CL:0002553 ! fibroblast of lung intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0002185 ! bronchus creation_date: 2015-03-31T21:16:22Z [Term] id: CL:2000095 name: cord blood hematopoietic stem cell def: "Any hematopoietic stem cell that is part of a umbilical cord blood." [GOC:TermGenie] is_a: CL:0002246 ! peripheral blood stem cell is_a: CL:0002352 ! gestational hematopoietic stem cell intersection_of: CL:0000037 ! hematopoietic stem cell intersection_of: part_of UBERON:0012168 ! umbilical cord blood relationship: dc-contributor https://www.wikidata.org/entity/Q35563349 relationship: part_of UBERON:0012168 ! umbilical cord blood creation_date: 2015-05-26T18:58:34Z [Term] id: CL:3000000 name: ciliated epithelial cell of esophagus def: "A ciliated epithelial cell of the esophagus." [GOC:CellBLAST, PMID:29802404] is_a: CL:0000067 ! ciliated epithelial cell is_a: CL:0002252 ! epithelial cell of esophagus intersection_of: CL:0000067 ! ciliated epithelial cell intersection_of: part_of UBERON:0001976 ! epithelium of esophagus relationship: dc-contributor https://www.wikidata.org/entity/Q97529981 relationship: part_of UBERON:0001976 ! epithelium of esophagus creation_date: 2019-02-09T16:40:30Z [Term] id: CL:3000004 name: peripheral sensory neuron def: "Peripheral sensory neuron." [GOC:CellBLAST, PMID:30096314] is_a: CL:0000101 ! sensory neuron is_a: CL:2000032 ! peripheral nervous system neuron intersection_of: CL:2000032 ! peripheral nervous system neuron intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: dc-contributor https://www.wikidata.org/entity/Q97529981 creation_date: 2019-02-25T19:34:33Z [Term] id: CL:4023072 name: brain vascular cell def: "A cell that is part of the brain vasculature." [DOI:10.1101/2022.10.12.511898] subset: human_reference_atlas is_a: CL:0000003 ! native cell is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0008998 ! vasculature of brain relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 relationship: part_of UBERON:0008998 ! vasculature of brain property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4023079 name: midbrain-derived inhibitory neuron def: "A GABAergic inhibitory neuron that is derived from the midbrain." [DOI:10.1101/2022.10.12.511898] subset: human_reference_atlas is_a: CL:0000540 ! neuron is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: CL:0000540 ! neuron intersection_of: develops_from UBERON:0001891 ! midbrain relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 relationship: develops_from CL:0000031 ! neuroblast (sensu Vertebrata) relationship: develops_from UBERON:0001891 ! midbrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4023154 name: myelinating glial cell def: "A glial cell that myelinates axonal processes." [DOI:10.1007/3-540-29623-9_3240] is_a: CL:0000125 ! glial cell intersection_of: CL:0000125 ! glial cell intersection_of: has_part GO:0043209 ! myelin sheath relationship: dc-contributor https://orcid.org/0000-0001-7258-9596 relationship: has_part GO:0043209 ! myelin sheath [Term] id: CL:4023168 name: somatosensory neuron def: "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli." [PMID:22865660] is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: part_of UBERON:0003942 ! somatosensory system relationship: dc-contributor http://orcid.org/0000-0001-7258-9596 relationship: part_of UBERON:0003942 ! somatosensory system [Term] id: CL:4028001 name: pulmonary capillary endothelial cell def: "Any capillary endothelial cell that is part of a lung." [] synonym: "lung capillary endothelial cell" EXACT [] is_a: CL:0002144 ! capillary endothelial cell is_a: CL:2000016 ! lung microvascular endothelial cell intersection_of: CL:0002144 ! capillary endothelial cell intersection_of: part_of UBERON:0002048 ! lung relationship: dc-contributor https://orcid.org/0000-0002-3293-5463 creation_date: 2021-11-23T02:31:40Z [Term] id: CL:4030025 name: renal cortical fibroblast def: "A fibroblast that is located in the renal cortical interstitium." [PMID:10559635] comment: Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin. {xref="PMID:16230044"} synonym: "kidney cortical fibroblast" EXACT [] is_a: CL:1000681 ! kidney cortex interstitial cell is_a: CL:1000692 ! kidney interstitial fibroblast intersection_of: CL:0000057 ! fibroblast intersection_of: part_of UBERON:0005270 ! renal cortex interstitium relationship: dc-contributor https://orcid.org/0000-0002-1773-2692 property_value: http://purl.org/dc/terms/date "2022-07-05T15:50:17Z" xsd:dateTime [Term] id: CL:4030029 name: blood lymphocyte def: "A lymphocyte located in blood." [https://orcid.org/0000-0001-9990-8331] subset: blood_and_immune_upper_slim is_a: CL:0000542 ! lymphocyte is_a: CL:2000001 ! peripheral blood mononuclear cell intersection_of: CL:0000542 ! lymphocyte intersection_of: part_of UBERON:0000178 ! blood relationship: dc-contributor https://orcid.org/0000-0002-1773-2692 property_value: http://purl.org/dc/terms/date "2022-11-04T14:40:00Z" xsd:dateTime [Term] id: CL:4030031 name: interstitial cell def: "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes." [PMID:24987007] is_a: CL:0000003 ! native cell intersection_of: CL:0000003 ! native cell intersection_of: part_of UBERON:0005169 ! interstitial tissue relationship: dc-contributor https://orcid.org/0000-0002-1773-2692 relationship: part_of UBERON:0005169 ! interstitial tissue property_value: http://purl.org/dc/terms/date "2022-11-30T14:35:08Z" xsd:dateTime [Term] id: CL:4030034 name: respiratory ciliated cell def: "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium." [PMID:18757316, PMID:21364219] synonym: "ciliated cell of the respiratory tract" EXACT [] is_a: CL:0000064 ! ciliated cell is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: CL:0000064 ! ciliated cell intersection_of: part_of UBERON:0004802 ! respiratory tract epithelium relationship: part_of UBERON:0004802 ! respiratory tract epithelium property_value: http://purl.org/dc/terms/date "2023-01-25T11:06:01Z" xsd:dateTime [Term] id: CL:4030035 name: dental pulp stem cell def: "A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation." [DOI:10.1177/154405910208100806, https://orcid.org/0000-0002-2825-0621] synonym: "DPSC" EXACT abbreviation [] is_a: CL:0000034 ! stem cell is_a: CL:0002148 ! dental pulp cell intersection_of: CL:0000034 ! stem cell intersection_of: part_of UBERON:0001754 ! dental pulp property_value: http://purl.org/dc/terms/date "2023-01-10T14:02:02Z" xsd:dateTime [Term] id: CL:4030040 name: endometrial ciliated epithelial cell def: "A ciliated cell of the endometrial epithelium. The cilia of this cell type help move mucus from glandular tissue of the endometrium." [https://www.nature.com/articles/s41591-020-1040-z, https://www.proteinatlas.org/humanproteome/single+cell+type/Glandular+epithelial+cells#endometrialciliatedcells] comment: In human samples, the expression of FOXJ1 protein, a regulator for motile cilia with epithelial lineage identity, has been noted. {xref="ttps://www.nature.com/articles/s41591-020-1040-z"} synonym: "ciliated cell of the endometrium" EXACT [] synonym: "ciliated cell of the uterus" BROAD [] synonym: "endometrium ciliated epithelial cell" EXACT [] synonym: "uterine ciliated cell" BROAD [] is_a: CL:0000067 ! ciliated epithelial cell is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: CL:0000064 ! ciliated cell intersection_of: CL:0000066 ! epithelial cell intersection_of: part_of UBERON:0004811 ! endometrium epithelium relationship: part_of UBERON:0004811 ! endometrium epithelium property_value: http://purl.org/dc/terms/date "2023-02-09T11:25:14Z" xsd:dateTime [Term] id: CL:4033005 name: serous secreting cell of bronchus submucosal gland def: "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland." [PMID:5487122, PMID:9651178] is_a: CL:0000152 ! exocrine cell is_a: CL:0019001 ! tracheobronchial serous cell intersection_of: CL:0000313 ! serous secreting cell intersection_of: part_of UBERON:8410043 ! bronchus submucosal gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:8410043 ! bronchus submucosal gland [Term] id: CL:4033008 name: vein endothelial cell of respiratory system def: "A(n) vein endothelial cell that is part of a(n) respiratory system." [PMID:34030460] subset: human_reference_atlas is_a: CL:0002543 ! vein endothelial cell intersection_of: CL:0002543 ! vein endothelial cell intersection_of: part_of UBERON:0001004 ! respiratory system relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0001004 ! respiratory system property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033017 name: bronchiolar smooth muscle cell def: "A smooth muscle cell that is part of a bronchiole." [ISBN:9781260462982, PMID:15347627] subset: human_reference_atlas is_a: CL:0019019 ! tracheobronchial smooth muscle cell intersection_of: CL:0000192 ! smooth muscle cell intersection_of: part_of UBERON:0002186 ! bronchiole relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 relationship: part_of UBERON:0002186 ! bronchiole property_value: http://purl.org/dc/terms/date "2023-03-16T09:38:17Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033018 name: lung megakaryocyte def: "A megakaryocyte that is resident in the lung connective tissue." [PMID:33351116] subset: human_reference_atlas synonym: "lung MKs" RELATED PLURAL [PMID:33351116] is_a: CL:0000556 ! megakaryocyte relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 property_value: http://purl.org/dc/terms/date "2023-03-16T11:31:23Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033020 name: mucus secreting cell of trachea gland def: "A mucus secreting cell that is part of a submucosal gland of the trachea." [PMID:18931053, PMID:29656943] subset: human_reference_atlas synonym: "tracheal submucosal gland mucous cell" EXACT [PMID:18931053] is_a: CL:0000307 ! tracheal epithelial cell is_a: CL:4033037 ! mucus secreting cell of tracheobronchial tree submucosal gland intersection_of: CL:0000319 ! mucus secreting cell intersection_of: part_of UBERON:0005203 ! trachea gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 relationship: part_of UBERON:0005203 ! trachea gland property_value: http://purl.org/dc/terms/date "2023-03-16T13:03:13Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033022 name: mucus secreting cell of bronchus submucosal gland def: "A mucus secreting cell of a submucosal gland of the bronchus." [PMID:19965983] subset: human_reference_atlas synonym: "bronchial gland mucous cell" EXACT [PMID:5487122] is_a: CL:0002328 ! bronchial epithelial cell is_a: CL:4033037 ! mucus secreting cell of tracheobronchial tree submucosal gland intersection_of: CL:0000319 ! mucus secreting cell intersection_of: part_of UBERON:8410043 ! bronchus submucosal gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: dc-contributor https://orcid.org/0000-0002-9185-3994 relationship: part_of UBERON:8410043 ! bronchus submucosal gland property_value: http://purl.org/dc/terms/date "2023-03-16T15:12:52Z" xsd:dateTime property_value: RO:0002175 NCBITaxon:9606 [Term] id: CL:4033037 name: mucus secreting cell of tracheobronchial tree submucosal gland def: "A mucus secreting cell of a submucosal gland of the tracheobronchial tree." [PMID:30864819] is_a: CL:0000152 ! exocrine cell is_a: CL:0000319 ! mucus secreting cell is_a: CL:0002202 ! epithelial cell of tracheobronchial tree intersection_of: CL:0000319 ! mucus secreting cell intersection_of: part_of UBERON:0007196 ! tracheobronchial tree intersection_of: part_of UBERON:8410077 ! airway submucosal gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:8410077 ! airway submucosal gland property_value: http://purl.org/dc/terms/date "2023-04-20T10:55:50Z" xsd:dateTime [Term] id: CL:4033049 name: taste receptor cell of tongue def: "A taste receptor cell that is part of a taste bud of a tongue." [DOI:10.1111/j.1096-3642.1981.tb01137.x, http://www.nejohnston.org/Birds/documents/AvianTongues_Johnston.pdf, PMID:10052456, PMID:28655883] synonym: "gustatory cell of tongue" RELATED [DOI:10.1016/s0022-5320(69)80043-2] is_a: CL:0000209 ! taste receptor cell is_a: CL:0002251 ! epithelial cell of alimentary canal is_a: CL:0002319 ! neural cell intersection_of: CL:0000209 ! taste receptor cell intersection_of: part_of UBERON:0014451 ! tongue taste bud relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0014451 ! tongue taste bud property_value: http://purl.org/dc/terms/date "2023-05-03T07:59:58Z" xsd:dateTime [Term] id: CL:4033050 name: catecholaminergic neuron def: "A neuron that releases catecholamine as a neurotransmitter." [ISBN:0521442516, PMID:12094209] comment: Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis. {xref="https://orcid.org/0000-0002-2244-7917", xref="PMID:12128258", xref="PMID:10191060", xref="PMID:34880760"} is_a: CL:0000151 ! secretory cell is_a: CL:0000540 ! neuron intersection_of: CL:0000540 ! neuron intersection_of: capable_of GO:0160043 ! catecholamine secretion, neurotransmission relationship: capable_of GO:0160043 ! catecholamine secretion, neurotransmission relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 property_value: http://purl.org/dc/terms/date "2023-05-18T12:07:45Z" xsd:dateTime [Term] id: FOVT:0000001 name: body length with tail def: "The length of a body that includes the tail." [https://orcid.org/0000-0003-2699-3066] comment: This is measured from the snout to the end of the tail along the anterior-posterior axis in four-legged vertebrates. synonym: "total length" EXACT [] is_a: OBA:VT0001256 ! body length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000002 name: body length without tail def: "The length of a body that excludes a tail." [https://orcid.org/0000-0003-2699-3066] comment: This is measured from the snout to before the tail, usually ending at the anus in four-legged vertebrates. synonym: "head-body length" EXACT [] synonym: "snout-vent length" RELATED [] is_a: OBA:VT0001256 ! body length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000003 name: pes length with nail def: "A length measurement of a hindfoot that includes the nail." [https://orcid.org/0000-0003-2699-3066] def: "The length of a hindfoot that includes the nail." [https://orcid.org/0000-0003-2699-3066] synonym: "hindfoot length" RELATED [] synonym: "hindfoot length length with nail" EXACT [] is_a: OBA:1000049 ! pes length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0000004 name: pes length without nail def: "The length of a hindfoot that excludes the nail." [https://orcid.org/0000-0003-2699-3066] synonym: "hindfoot length" RELATED [] synonym: "hindfoot length without nail" EXACT [] is_a: OBA:1000049 ! pes length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0000005 name: ear length to notch def: "The length of a line of an ear from a helix of the outer ear to an intertragus insicusure of an ear." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0003426 ! external ear length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000006 name: femur length from greater trochanter to lateral condyle def: "The length from a lateral condyle of femur to a greater trochanter of a femur." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "femur lateral length" EXACT [] synonym: "femur maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004348 ! femur length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000007 name: obsolete femur length from caput to medial condyle def: "OBSOLETE The length from a medial condyle of femur to a head of femur." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9780873659505] comment: term doesn't exist, it should be lateral condyle synonym: "femur greatest length from caput femoris (GLC)" EXACT [ISBN:9780873659505] synonym: "femur medial length" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001070 [Term] id: FOVT:0000008 name: humerus length from trochlea to caput def: "The length from a trochlea of a humerus to a proximal head of a humerus (caput)." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus greatest length from caput (GLC)" RELATED [ISBN:9780873659505] synonym: "humerus maximal length from caput (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004350 ! humerus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000009 name: humerus length from trochlea to greater tubercle def: "The length from a trochlea of a humerus to a ventral tubercle (greater tubercle) of a humerus." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "humerus length from trochlea to ventral tubercle" EXACT [] synonym: "humerus maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004350 ! humerus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000010 name: obsolete talus distal articular breadth def: "OBSOLETE Medial-lateral width of the distal end of an astragalus." [] comment: astragalus head breadth comment: Redundant with FOVT:0000017 synonym: "astragalus greatest breadth distal" EXACT [] synonym: "talus distal width ML" EXACT [] synonym: "talus head width" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0000017 [Term] id: FOVT:0000012 name: obsolete width of the trochlea of talus def: "OBSOLETE Length between the proximal-most points of the medial and lateral trochlear ridges of an astragalus." [] comment: This is not a measurement FOVT has a need for. synonym: "breadth of the trochlea" EXACT [] synonym: "breadth of the trochlea of talus" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0000013 name: astragalus lateral length def: "The length of the lateral side of an astragalus (talus) along the proximal-distal axis." [ISBN:9780873659505] synonym: "astragalus greatest length of the lateral half (GLl)" RELATED [ISBN:9780873659505] synonym: "talus lateral length" EXACT [] is_a: FOVT:0000020 ! astragalus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0000014 name: obsolete talus medial depth def: "OBSOLETE The depth of the medial ridge of a trochlea of an astragalus along the anterior-posterior axis." [] comment: duplicate term synonym: "astragalus medial depth" EXACT [] synonym: "astragalus medial width AP" EXACT [] synonym: "talus medial width AP" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001043 [Term] id: FOVT:0000015 name: obsolete length of the lateral side of talus def: "OBSOLETE Length of the lateral side of an astragalus." [] comment: Redundant term property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0000013 [Term] id: FOVT:0000016 name: astragalus medial length def: "The length of the medial side of an astragalus (talus) along the proximal-distal axis." [ISBN:9780873659505] synonym: "astragalus greatest length of the medial half (GLm)" RELATED [ISBN:9780873659505] synonym: "talus medial length" EXACT [] is_a: FOVT:0000020 ! astragalus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0000017 name: astragalus distal articular breadth def: "The length an astragalus head (distal articular facet, facet for the navicular) along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: The points for this measurement are the medial-most point on the articular surface for the calcaneum on the astragalus (talus) to the lateral-most point of the trochleated head of an astragalus (talus). synonym: "astragalus breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] synonym: "astragalus distal articular breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "astragalus distal articular width" EXACT [] synonym: "talus distal articular breadth" EXACT [] is_a: FOVT:0000021 ! astragalus breadth intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:4200181 ! astragalus head relationship: characteristic_of UBERON:4200181 ! astragalus head relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000018 name: astragalus distal articular depth def: "The length of an astragalus head (distal articular facet, facet for the navicular)." [ISBN:9004086161\, 9789004086166] comment: This measurement is perpendicular to the astragalus distal articular breadth measurement. synonym: "astragalus distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "talus distal articular depth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:4200181 ! astragalus head relationship: characteristic_of UBERON:4200181 ! astragalus head relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000020 name: astragalus length {xref="ISBN:9780873659505"} def: "The length of an astragalus (talus) along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "astragalus greatest height (GH)" EXACT [ISBN:9780873659505] synonym: "astragalus maximal length (M1)" EXACT [ISBN:9004086161\, 9789004086166] synonym: "talus length" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002395 ! talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000021 name: astragalus breadth def: "The width of an astragalus (talus) along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "astragalus greatest breadth (GB)" RELATED [ISBN:9780873659505] synonym: "astragalus maximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "astragalus width" EXACT [] synonym: "talus breadth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0002395 ! talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000022 name: calcaneus length def: "The maximal length of a calcaneus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "calcaneus greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "calcaneus maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001450 ! calcaneus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000023 name: calcaneus distal breadth def: "The length of a distal end of a caclcaneus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This measurement is taken from the lateral side of the middle articular facet for talus of calcaneus to the medial side of the curboid facet of calcaneum. synonym: "calcaneus distal maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "calcaneus distal width" EXACT [] synonym: "calcaneus greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0000025 name: tibia lateral length def: "The length of the lateral side of a tibia along the proximal-distal axis." [ISBN:9780873659505] synonym: "tibia length of the lateral part (LI)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004357 ! tibia length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0000026 name: obsolete tibia diaphysis width def: "OBSOLETE The width of shaft or diaphysis of a tibia." [https://orcid.org/0000-0003-2699-3066] comment: unneeded term synonym: "tibia width" BROAD [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: OBA:VT1000289 [Term] id: FOVT:0000027 name: obsolete tibia proximal width def: "OBSOLETE The width of the proximal end of a tibia." [https://orcid.org/0000-0003-2699-3066] comment: not needed synonym: "breadth of proximal end of tibia" EXACT [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001006 [Term] id: FOVT:0000028 name: obsolete tibia distal width def: "OBSOLETE The width of the distal end of a tibia." [https://orcid.org/0000-0003-2699-3066] comment: not needed synonym: "breadth of distal end of tibia" EXACT [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001004 [Term] id: FOVT:0000029 name: obsolete tibia distal breadth def: "OBSOLETE The depth of the distal end of a tibia." [] comment: duplicate term synonym: "tibia distal width ML" EXACT [] property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001004 [Term] id: FOVT:0000030 name: tooth row length def: "The length of a tooth row." [https://orcid.org/0000-0003-2699-3066] is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0009678 ! tooth row relationship: characteristic_of UBERON:0009678 ! tooth row property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0000032 name: snout-vent length def: "Body length from tip of nose (snout) to cloaca." [https://orcid.org/0000-0003-2699-3066] synonym: "body length without tail" RELATED [] synonym: "head-body length" RELATED [] is_a: OBA:VT0001256 ! body length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:8292 property_value: measured_in_taxon NCBITaxon:8504 [Term] id: FOVT:0001003 name: ear length to tragus def: "The length of a line of an ear from a helix of the outer ear to a tragus of an ear." [https://orcid.org/0000-0003-2699-3066] comment: This measurement is often taken in bats. is_a: OBA:0003426 ! external ear length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001004 name: tibia distal breadth def: "The length of a distal epiphysis of a tibia along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "tibia distal maximal breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "tibia distal width" EXACT [] is_a: OBA:1000196 ! distal epiphysis of tibia quality is_a: OBA:VT1000289 ! tibia width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004405 ! distal epiphysis of tibia relationship: characteristic_of UBERON:0004405 ! distal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001005 name: tibia distal depth def: "The length of a distal epiphysis of a tibia along the anterior-posterior axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia depth of the distal end (Dd)" RELATED [] synonym: "tibia distal maximal depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000196 ! distal epiphysis of tibia quality is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004405 ! distal epiphysis of tibia relationship: characteristic_of UBERON:0004405 ! distal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9979 [Term] id: FOVT:0001006 name: tibia proximal breadth def: "The length of a proximal epiphysis of a tibia along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "tibia proximal maximal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "tibia proximal width" EXACT [] is_a: OBA:0003298 ! proximal epiphysis of tibia size is_a: OBA:VT1000289 ! tibia width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0008772 ! proximal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001007 name: tibia proximal depth def: "The length of a proximal epiphysis of a tibia along the anterior-posterior axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166] synonym: "tibia proximal maximal depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003298 ! proximal epiphysis of tibia size is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0008772 ! proximal epiphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001008 name: tibia diaphysis breadth def: "The length of a diaphysis of a tibia along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "tibia diaphysis width" EXACT [] synonym: "tibia minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "tibia smallest diameter of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT1000289 ! tibia width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0013280 ! diaphysis of tibia relationship: characteristic_of UBERON:0013280 ! diaphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001009 name: tibia diaphysis depth def: "The length of a diaphysis of a tibia along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "tibia minimal depth of diaphysis (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0013280 ! diaphysis of tibia relationship: characteristic_of UBERON:0013280 ! diaphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001021 name: tibia medial length def: "The length of the medial side of a tibia along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "tibia medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004357 ! tibia length property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001022 name: obsolete tibia greatest length def: "OBSOLETE The greatest length of a tibia from the proximal-most point of a tibia to the distal-most point of a tibia." [] {http://purl.obolibrary.org/obo/IAO_0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", http://purl.obolibrary.org/obo/IAO_0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: duplicate of a term in OBA property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: OBA:VT0004357 [Term] id: FOVT:0001023 name: tibia diaphysis circumference def: "The circumference of a diaphysis of a tibia." [ISBN:9780873659505] synonym: "tibia smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0013280 ! diaphysis of tibia relationship: characteristic_of UBERON:0013280 ! diaphysis of tibia property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001024 name: femur proximal breadth def: "The length of a proximal epiphysis of a femur along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "femur proximal maximal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur proximal width" EXACT [] is_a: OBA:0002389 ! proximal epiphysis of femur size is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004412 ! proximal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001025 name: femur trochanter breadth def: "The length of the lesser trochanter of femur along the medial-lateral axis." [ISBN:9780873659505] synonym: "femur breadth of the region of the trochanter tertius (BTr)" RELATED [ISBN:9780873659505] synonym: "femur trochanter width" EXACT [] is_a: OBA:0002863 ! lesser trochanter size is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0002504 ! lesser trochanter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001026 name: femur caput depth def: "The length of a head of femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur depth of the caput femoris (DC)" RELATED [ISBN:9780873659505] synonym: "femur maximal depth of caput femoris (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002864 ! head of femur size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0006767 ! head of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001027 name: femur diaphysis breadth def: "The length of a diaphysis of femur along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur diaphysis width" EXACT [] synonym: "femur minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0006862 ! diaphysis of femur relationship: characteristic_of UBERON:0006862 ! diaphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001028 name: femur diaphysis circumference def: "The circumference of the diaphysis of a femur." [ISBN:9780873659505] synonym: "femur circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0010014 ! femur circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0006862 ! diaphysis of femur relationship: characteristic_of UBERON:0006862 ! diaphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001029 name: femur distal breadth def: "The length of a distal epiphysis of a femur along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "femur breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "femur distal maximal breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur distal width" EXACT [] is_a: OBA:0002726 ! distal epiphysis of femur size is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004406 ! distal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001030 name: femur proximal depth def: "The length of a proximal epiphysis of a femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "femur proximal maximal depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002389 ! proximal epiphysis of femur size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004412 ! proximal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001031 name: femur distal depth def: "The length of a distal epiphysis of a femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "femur distal maximal depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002726 ! distal epiphysis of femur size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004406 ! distal epiphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001032 name: femur trochlea breadth def: "The length of the medial condyle (trochlea) of a femur along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "femur maximal breadth of the trochlea (M9)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "femur trochlea with" EXACT [] is_a: OBA:1000180 ! distal epiphysis of femur quality is_a: OBA:VT1000666 ! femur width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0009984 ! medial condyle of femur relationship: characteristic_of UBERON:0009984 ! medial condyle of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001033 name: femur diaphysis depth def: "The length of a diaphysis of femur along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "femur diameter perpendicular to, and at the level of, femur diaphysis breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0006862 ! diaphysis of femur relationship: characteristic_of UBERON:0006862 ! diaphysis of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001034 name: humerus diaphysis breadth def: "The length of a diaphysis of humerus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus diaphysis width" EXACT [] synonym: "humerus minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002474 ! humerus diaphysis size is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004652 ! humerus diaphysis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001035 name: humerus proximal breadth def: "The length of a proximal epiphysis of a humerus along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is often measured at the epicondyles. synonym: "humerus breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "humerus proximal maximal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus proximal width" EXACT [] is_a: OBA:1000394 ! proximal epiphysis of humerus quality is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004411 ! proximal epiphysis of humerus relationship: characteristic_of UBERON:0004411 ! proximal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: not_measured_in_taxon NCBITaxon:9611 property_value: not_measured_in_taxon NCBITaxon:9979 [Term] id: FOVT:0001036 name: humerus trochlea breadth def: "The length of a trochlea of a humerus along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "humerus breadth of trochlea (BT)" RELATED [ISBN:9780873659505] synonym: "humerus maximal breadth of the trochlea (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus trochlea width" EXACT [] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000144 ! trochlea of humerus relationship: characteristic_of UBERON:0000144 ! trochlea of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001037 name: humerus distal depth def: "The length of a distal epiphysis of a humerus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus distal maximal depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004404 ! distal epiphysis of humerus relationship: characteristic_of UBERON:0004404 ! distal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001038 name: humerus proximal depth def: "The length of a proximal epiphysis of a humerus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is measured at the level of the median tubercle. synonym: "humerus depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "humerus proximal depth at the level of the median turbecle (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000394 ! proximal epiphysis of humerus quality is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004411 ! proximal epiphysis of humerus relationship: characteristic_of UBERON:0004411 ! proximal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9979 [Term] id: FOVT:0001039 name: humerus distal breadth def: "The length of a distal epiphysis of a humerus along the medial-lateral axis." [ISBN:9780873659505] comment: This is often measured across the distal trochlea. {xref="ISBN:9780873659505"} synonym: "humerus breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "humerus distal trochlear breadth" EXACT [] synonym: "humerus distal width" EXACT [] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT1000280 ! humerus width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004404 ! distal epiphysis of humerus relationship: characteristic_of UBERON:0004404 ! distal epiphysis of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001040 name: humerus diaphysis depth def: "The length of the diaphysis of a humerus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus diameter perpendicular to, and at the level of, humerus diaphysis breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002474 ! humerus diaphysis size is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004652 ! humerus diaphysis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001041 name: obsolete astragalus width def: "OBSOLETE The width of an astragalus (talus)." [https://orcid.org/0000-0003-2699-3066] comment: same as astragalus breadth synonym: "talus width" EXACT [] property_value: IAO:0000114 IAO:0000423 property_value: IAO:0000117 https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0000021 [Term] id: FOVT:0001042 name: astragalus lateral depth def: "The length of the lateral side of an astragalus (talus) along the anterior-posterior axis." [ISBN:9780873659505] synonym: "astragalus depth of the lateral half (DI)" RELATED [ISBN:9780873659505] synonym: "talus lateral depth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0001043 name: astragalus medial depth def: "The length of the medial side of an astragalus (talus) along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "astragalus depth of medial half (DM)" RELATED [ISBN:9780873659505] synonym: "astragalus maximal medial depth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "talus medial depth" EXACT [] is_a: OBA:VT0005110 ! talus size trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0001044 name: astragalus distal breadth def: "The length of the distal end of an astragalus (talus) along the medial-lateral axis." [DOI:10.1007/s00267-006-0240-8, ISBN:9780873659505] synonym: "astragalus AST4" RELATED [DOI:10.1007/s00267-006-0240-8] synonym: "astragalus breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "astragalus distal width" EXACT [] synonym: "talus distal breadth" EXACT [] is_a: FOVT:0000021 ! astragalus breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:91561 [Term] id: FOVT:0001045 name: trochlea tali length def: "The length of the trochlea tali (medial condyle) of an astragulas (talus) along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "astragalus diameter of medial condyle" EXACT [] synonym: "astragalus length of the medial part of the trochlea tali (LmT)" RELATED [ISBN:9780873659505] synonym: "astragalus maximal diameter of the medial condyle (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "astragalus medial trochlea tali length" EXACT [] synonym: "talus medial condyle length" EXACT [] is_a: FOVT:0000020 ! astragalus length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:7500066 ! medial condyle of talus relationship: characteristic_of UBERON:7500066 ! medial condyle of talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001046 name: astragalus trochlea breadth def: "The length of the trochlea of an astragalus (talus) along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] {comment="ISBN:9780873659505"} synonym: "astragalus condylar breadth" EXACT [] synonym: "astragalus trochlea width" EXACT [] synonym: "atragalus breadth of the trochlea (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "talus condylar breadth" EXACT [] synonym: "talus trochlea breadth" EXACT [] is_a: FOVT:0000021 ! astragalus breadth intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:7500063 ! trochlea of talus relationship: characteristic_of UBERON:7500063 ! trochlea of talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001047 name: calcaneus proximal length def: "The length of the proximal end of a calcaneus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] comment: This measurement is from the posterior articular facet for talus of calcaneus to calcaneal tuber. synonym: "calcaneus length of the proximal part (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0000022 ! calcaneus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001048 name: calcaneus distal depth def: "The length of a distal end of a caclcaneus along the anterior-posterior axis." [https://ethnobiology.org/sites/default/files/pdfs/JoE/7-1/Purdue1987.pdf, ISBN:9004086161\, 9789004086166] comment: The anterior-most feature is the tubercle of calcaneus. synonym: "calcaneus distal maximal depth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "calcaneus lateral depth (CALD)" RELATED [https://eprints.nottingham.ac.uk/50198/] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001053 name: gutted body mass def: "The mass of a multicellur organism after removing internal organs." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001054 name: skinned body mass def: "The mass of a multicellular organism after being skinned." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001055 name: mass of skeleton def: "The mass of a multicellur organism skeletal elements (i.e., bones) without skin, internal organs, or other soft tissue." [https://orcid.org/0000-0003-2699-3066] synonym: "bone mass" RELATED [] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001056 name: gutted and skinned body mass def: "The mass of a mutlicellular organism after being both gutted (i.e., internal organs removed) and skinned." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001057 name: testis length comment: The length of a testis. {xref="https://orcid.org/0000-0003-2699-3066"} is_a: FOVT:0001060 ! gonad length is_a: OBA:VT0001148 ! testes size trait intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000473 ! testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001058 name: right testis length comment: The length of a testis on the right side. {xref="https://orcid.org/0000-0003-2699-3066"} is_a: FOVT:0001057 ! testis length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004534 ! right testis relationship: characteristic_of UBERON:0004534 ! right testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001059 name: left testis length comment: The length of a testis on the left side. {xref="https://orcid.org/0000-0003-2699-3066"} is_a: FOVT:0001057 ! testis length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004533 ! left testis relationship: characteristic_of UBERON:0004533 ! left testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001060 name: gonad length comment: The length of a gonad. {xref="https://orcid.org/0000-0003-2699-3066"} is_a: OBA:0002017 ! gonad size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000991 ! gonad relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001061 name: humerus lateral length def: "The length of the lateral side of a humerus along the proximal-distal axis." [ISBN:9780873659505] comment: This measurement is from lateral tuberosity to lateral border of the trochlea. synonym: "humerus greatest length of lateral part (GLI)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004350 ! humerus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001062 name: ovary length def: "The length of an ovary." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001060 ! gonad length is_a: OBA:VT0001127 ! ovary size trait intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000992 ! ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001063 name: right ovary length def: "The length of an ovary on the right side." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001062 ! ovary length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002118 ! right ovary relationship: characteristic_of UBERON:0002118 ! right ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001064 name: left ovary length def: "The length of an ovary on the left side." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001062 ! ovary length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002119 ! left ovary relationship: characteristic_of UBERON:0002119 ! left ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001065 name: anterior tibial tuberosity length def: "The length of the anterior tibial tuberosity (fossa digitalis) along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "tibia length of the fossa digitalis (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000148 ! proximal epiphysis of tibia quality is_a: OBA:VT0004357 ! tibia length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:7500062 ! tibial tuberosity relationship: characteristic_of UBERON:7500062 ! tibial tuberosity relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001066 name: obsolete humerus proximal depth at median tubercle def: "OBSOLETE The length along the medial-lateral axis of the caput of the humerus." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: Redundant with another term synonym: "humerus proximal length AP at median tubercule" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001038 [Term] id: FOVT:0001067 name: humerus trochlear sulcus height def: "The length of the trochlear sulcus (trochlear groove) of a humerus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus minimal trochlear height (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:3000785 ! trochlear groove of humerus relationship: characteristic_of UBERON:3000785 ! trochlear groove of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001068 name: humerus medial trochlear height def: "The length of the distal medial trochlea of a humerus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus maximal trochlear height (H9)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "humerus medial trochlear depth" EXACT [] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0000144 ! trochlea of humerus relationship: characteristic_of UBERON:0000144 ! trochlea of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001069 name: humerus trochlear height at sagittal crest def: "The length of the sagittal crest of a trochlea of a humerus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "humerus trochlear depth" EXACT [] synonym: "humerus trochlear depth at sagittal crest" EXACT [] synonym: "trochlear height at the sagittal creast (near the condyle) (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000568 ! distal epiphysis of humerus quality is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:7500061 ! trochlear ridge of humerus relationship: characteristic_of UBERON:7500061 ! trochlear ridge of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001070 name: femur length from caput to lateral condyle def: "The length from a head of femur (caput) to a lateral condyle of femur." [ISBN:9004086161\, 9789004086166] synonym: "femur greatest length from caput femoris (GLC)" RELATED [ISBN:9780873659505] synonym: "femur length from caput femoris to lateral condyle (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004348 ! femur length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001071 name: olecranon length def: "The length of an olecranon of an ulna along the proximal-distal axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "ulna length of the olecranon (LO)" RELATED [ISBN:9780873659505] synonym: "ulna length of the olecranon (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004370 ! ulna length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0006810 ! olecranon relationship: characteristic_of UBERON:0006810 ! olecranon relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001072 name: ulna proximal articular breadth def: "The length of the humeral facet of an ulna along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "ulna facies articularis proximalis breadth" EXACT [] synonym: "ulna breadth across the coronoid process, breadth of the proximal articular surface (BPC)" RELATED [ISBN:9780873659505] synonym: "ulna coronoid process breadth" EXACT [] synonym: "ulna maximal articular breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "ulna proximal articula width" EXACT [] is_a: OBA:0002379 ! ulna size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:4200203 ! humeral facet on the ulna relationship: characteristic_of UBERON:4200203 ! humeral facet on the ulna relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001073 name: obsolete ulna width {xref="https://orcid.org/0000-0003-2699-3066"} comment: not needed relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001074 name: olecranon depth def: "The length of an olecranon of an ulna along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: Olecranon depth is often measured at the epicondyles. synonym: "ulna minimal depth of the olecranon (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "ulna smallest depth of the olecranon (SDO)" RELATED [ISBN:9780873659505] is_a: OBA:0002379 ! ulna size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0006810 ! olecranon relationship: characteristic_of UBERON:0006810 ! olecranon relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001075 name: ulna lateral length def: "The length of the lateral side of an ulna along the proximal-distal axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9780873659505] synonym: "ulna greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004370 ! ulna length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001076 name: ulna depth across the process anaconaeus def: "The length of the humeral facet of an ulna along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "depth across the processus anconaeus (M5) (DPA)" RELATED [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] is_a: OBA:0002379 ! ulna size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:4200203 ! humeral facet on the ulna relationship: characteristic_of UBERON:4200203 ! humeral facet on the ulna relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001077 name: length of astragalus along the midline def: "The length along the midline of an astragalus (talus) along the proximal-distal axis." [DOI:10.1007/s00267-006-0240-8] comment: This measurement is from the astragalus head (distal articular facet for the navicular) to sulcus tali. synonym: "astragalus AST3" RELATED [DOI:10.1007/s00267-006-0240-8] synonym: "length of talus along the midline" EXACT [] is_a: FOVT:0000020 ! astragalus length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001078 name: breadth of calcaneal body def: "The length of a calcaneal body along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] comment: This is the narrowest section of the calcaneus. synonym: "calcaneus minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "width of calcaneal body" EXACT [] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:7500093 ! calcaneal body relationship: characteristic_of UBERON:7500093 ! calcaneal body relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001079 name: obsolete calcaneus width def: "OBSOLETE The width of a calcaneus." [https://orcid.org/0000-0003-2699-3066] comment: not needed synonym: "calcaneus breadth" EXACT [] synonym: "calcaneus CALD" EXACT [DOI:10.1007/s00267-006-0240-8] synonym: "calcaneus length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001080 name: calcaneus proximal breadth def: "The length of the proximal end of a calcaneus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "calcaneus proximal maximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "calcaneus proximal width" EXACT [] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001081 name: calcaneus proximal depth def: "The length of the proximal end of a calcaneus from a lateral tubercle of calcaneus to a medial tubercle of calcaneus." [ISBN:9004086161\, 9789004086166] synonym: "calcaneus maximal depth" EXACT [] synonym: "calcaneus proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001082 name: depth of calcaneal body def: "The length of a calcaneal body along the anterior-posterior axis." [https://eprints.nottingham.ac.uk/50198/] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:7500093 ! calcaneal body relationship: characteristic_of UBERON:7500093 ! calcaneal body relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001123 name: radius medial length def: "The length of the medial side of a radius along the proximal-distal axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166] synonym: "radius medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004355 ! radius length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001124 name: radius lateral length def: "The length of the lateral side of a radius along the proximal-distal axis." [ISBN:9780873659505] synonym: "radius length of the lateral part (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004355 ! radius length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001125 name: radius diaphysis breadth def: "The length of a diaphysis of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "radius diaphysis width" EXACT [] synonym: "radius minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000380 ! diaphysis of radius quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001028 ! diaphysis of radius relationship: characteristic_of UBERON:0001028 ! diaphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001126 name: radius diaphysis depth def: "The length of a diaphysis of a radius along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "radius depth of diaphysis at level of radius diaphysis breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000380 ! diaphysis of radius quality is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0001028 ! diaphysis of radius relationship: characteristic_of UBERON:0001028 ! diaphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001127 name: radius proximal articular breadth def: "The length of an articular surface on the proximal end of a radius that interacts with the humerus along the medial-lateral axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "proximal articular width" EXACT [] synonym: "radius greatest breadth of the facies articularis proximalis (humeral articular surface (BFp)" RELATED [ISBN:9780873659505] synonym: "radius proximal articular width" EXACT [] synonym: "radius proximal artiuclar breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:4200204 ! humeral facet on radius relationship: characteristic_of UBERON:4200204 ! humeral facet on radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001128 name: radius proximal articular depth def: "The length of an articular surface on the proximal end of a radius that interacts with a humerus along the anterior-posterior axis." [https://doi.org/10.1111/j.1096-3642.1983.tb00098.x, ISBN:9004086161\, 9789004086166] synonym: "radius proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:4200204 ! humeral facet on radius relationship: characteristic_of UBERON:4200204 ! humeral facet on radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001129 name: radius proximal breadth def: "The length of a proximal epiphysis of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "radius greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "radius proximal maximal breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius proximal width" EXACT [] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000304 ! proximal epiphysis of radius quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004413 ! proximal epiphysis of radius relationship: characteristic_of UBERON:0004413 ! proximal epiphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001130 name: radius distal articular breadth def: "The width along the medial-lateral axis of the distal end of a radius." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "radius distal articular width" EXACT [] synonym: "radius facies articularis distalis breadth (M8)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:7500080 ! articular surface for carpals relationship: characteristic_of UBERON:7500080 ! articular surface for carpals relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001131 name: radius distal articular depth def: "The length of the articular surface on the distal end of a radius that interacts with the carpals along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "radius distal articular depth (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:7500080 ! articular surface for carpals relationship: characteristic_of UBERON:7500080 ! articular surface for carpals property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001132 name: radius distal breadth def: "The length of a distal epiphysis of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is often measured across the epicondyles. synonym: "radius distal maximal breadth (M10)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius distal width" EXACT [] synonym: "radius greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002716 ! distal epiphysis of radius size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004407 ! distal epiphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001133 name: radius length from the proximal articular surface to the distal articular surface def: "The length of a radius from the proximal articular surface to the distal articular surface." [ISBN:9780873659505] synonym: "radius physiological length (PL)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004355 ! radius length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001134 name: radius diaphysis circumference def: "The circumference of a diaphysis of a radius." [ISBN:9780873659505] synonym: "radius smallest circumference of diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002374 ! radius bone size is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000380 ! diaphysis of radius quality is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0001028 ! diaphysis of radius relationship: characteristic_of UBERON:0001028 ! diaphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001135 name: DEPRECATED metatarsal bone length comment: already in OBA property_value: seeAlso OBA:0004033 is_obsolete: true [Term] id: FOVT:0001136 name: obsolete metatarsal bone of digit 2 length def: "OBSOLETE The length of the metatarsal bone of digit 2 along the proximal-distal axis." [] {http://purl.obolibrary.org/obo/IAO_0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", http://purl.obolibrary.org/obo/IAO_0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T22:41:34Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0003272 [Term] id: FOVT:0001137 name: obsolete metatarsal bone of digit 3 length def: "OBSOLETE The length of a metatarsal bone of digit 3 along the proximal-distal axis." [] {http://purl.obolibrary.org/obo/IAO_0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", http://purl.obolibrary.org/obo/IAO_0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: class already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T22:44:56Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0002565 [Term] id: FOVT:0001138 name: obsolete metatarsal bone of digit 4 length def: "OBSOLETE The length of the metatarsal bone of digit 4 along the proximal-distal axis." [] {http://purl.obolibrary.org/obo/IAO_0000119="Eisenmann, Véra, and V. Eisenmann Michael O. Woodburne PY. Studying Fossil Horses: Collected Papers After the New York International Hipparion Conference, 1981. Vol. 1. Brill Archive, 1988.", http://purl.obolibrary.org/obo/IAO_0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: class already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T22:46:16Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0002567 [Term] id: FOVT:0001139 name: obsolete metatarsal bone of digit 5 length def: "OBSOLETE The length of a metatarsal bone of digit 5 along the proximal-distal axis." [] {http://purl.obolibrary.org/obo/IAO_0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: class already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-06-03T22:50:27Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: OBA:0002569 [Term] id: FOVT:0001140 name: fused metatarsal bones 3 and 4 length def: "The length of a fused metatarsal bones 3 and 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest length (GL)" RELATED [ISBN:9780873659505] is_a: FOVT:0001143 ! fused metapodial bones 3 and 4 length is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001141 name: metapodial bone length def: "The length of a metapodial bone." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone" EXACT [] is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003821 ! metapodium bone relationship: characteristic_of UBERON:0003821 ! metapodium bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001142 name: metapodial bone of digit 2 length def: "The length of a metapodial bone of digit 2." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 2" EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001143 name: fused metapodial bones 3 and 4 length def: "The length of fused metapodial bones 3 and 4." [ISBN:9780873659505] synonym: "length of fused metapodial bones 3 and 4" EXACT [] is_a: FOVT:0001141 ! metapodial bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0013586 ! fused metapodial bones 3 and 4 relationship: characteristic_of UBERON:0013586 ! fused metapodial bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001144 name: metapodial bone of digit 4 length def: "The length of a metapodial bone of digit 4." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 4" EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001145 name: metapodial bone of digit 5 length def: "The length of a metapodial bone of digit 5." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 5" EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001146 name: metapodial bone of digit 3 length def: "The length of a metapodial bone of digit 3." [https://orcid.org/0000-0003-2699-3066] synonym: "length of metapodial bone of digit 3." EXACT [] is_a: FOVT:0001141 ! metapodial bone length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001147 name: obsolete radius width def: "OBSOLETE The width of a radius." [https://orcid.org/0000-0003-2699-3066] synonym: "radius breadth" EXACT [] synonym: "width of radius bone" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001148 name: obsolete radius distal width def: "OBSOLETE The width of the distal end of a radius." [https://orcid.org/0000-0003-2699-3066] comment: not needed relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001132 [Term] id: FOVT:0001149 name: obsolete radius proximal width def: "OBSOLETE The width of the proximal end of a radius." [https://orcid.org/0000-0003-2699-3066] comment: unneeded term relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T00:54:08Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001147 [Term] id: FOVT:0001150 name: obsolete radius proximal articular width def: "OBSOLETE The width of the arcitular surface that articulates with the humerus located on the proximal end of a radius." [https://orcid.org/0000-0003-2699-3066] comment: unneeded term relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-06-17T00:57:18Z" xsd:dateTime property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001147 [Term] id: FOVT:0001151 name: obsolete fibula length def: "OBSOLETE The length of a fibula along the proximal-distal axis." [] {http://purl.obolibrary.org/obo/IAO_0000119="von den Driesch, Angela. A guide to the measurement of animal bones from archaeological sites: as developed by the Institut für Palaeoanatomie, Domestikationsforschung und Geschichte der Tiermedizin of the University of Munich . Vol. 1. Peabody Museum Press, 1976."} comment: Already exists in OBA. synonym: "length of fibula" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-07-22T21:20:50Z" xsd:dateTime is_obsolete: true replaced_by: OBA:VT0000482 [Term] id: FOVT:0001152 name: scapula dorsal length def: "The length of the dorsal side of a scapula along the proximal-distal axis." [ISBN:9780873659505] synonym: "scapula greatest dorsal length (Ld)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004340 ! scapula length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001153 name: scapula spine length def: "The length of a scapular spine along the proximal-distal axis." [ISBN:9780873659505] synonym: "scapula height along the spine (HS)" RELATED [ISBN:9780873659505] is_a: OBA:VT0004340 ! scapula length is_a: OBA:VT0004347 ! scapular spine morphology trait intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004651 ! scapula spine relationship: characteristic_of UBERON:0004651 ! scapula spine relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001154 name: scapula neck breadth def: "The length of the neck of a scapula." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: In non-apes (not Hominoidea), this is measured along the medial-lateral axis; in Apes (Hominoidea) this is measured along the anterior-posterior axis. synonym: "collum scapulae length" EXACT [] synonym: "scapula minimal breadth at the neck (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "scapula neck width" EXACT [] synonym: "smallest length of the collum scapulae (SLC)" RELATED [ISBN:9780873659505] is_a: FOVT:0001157 ! scapula depth intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018667 ! neck of scapula relationship: characteristic_of UBERON:0018667 ! neck of scapula relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001155 name: glenoid cavity length def: "The length of a glenoid cavity." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: In non-anatomical humans (i.e., not Homo), this is measured along the anterior-posterior axis; in anatomical humans (Homo) this is measured along the superior-inferior (upper-lower) axis. synonym: "scapula articular maximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "scapula length of glenoid cavity (LG)" RELATED [ISBN:9780873659505] is_a: OBA:0002741 ! glenoid fossa size is_a: OBA:VT0004340 ! scapula length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0006657 ! glenoid fossa relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001156 name: glenoid cavity breadth def: "The length of a glenoid cavity (glenoid fossa) along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "scapula articular maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "scapula breadth of glenoid cavity (BG)" RELATED [ISBN:9780873659505] is_a: FOVT:0001157 ! scapula depth is_a: OBA:0002741 ! glenoid fossa size intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0006657 ! glenoid fossa relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001157 name: scapula depth def: "The depth of a scapula along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "scapula maximal depth of spina (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0004343 ! scapula size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0006849 ! scapula relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001158 name: obsolete radius diaphysis width def: "OBSOLETE The width of the diaphysis of a radius." [ORCID: 0000-0003-2699-3066] comment: unneeded synonym: "IAO:0000423" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-07-27T23:38:42Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001147 [Term] id: FOVT:0001159 name: mass of viscera def: "The mass of the viscera (internal organs)." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0001259 ! body mass relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001160 name: obsolete skin mass def: "OBSOLETE The mass of the skin of an organism." [] {http://purl.obolibrary.org/obo/IAO_0000119="ORCID: 0000-0003-2699-3066"} comment: IAO:0000423 comment: Term already exists. relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-07-27T23:59:50Z" xsd:dateTime is_obsolete: true replaced_by: OBA:VT1000425 [Term] id: FOVT:0001161 name: radial condyle breadth def: "The length of a radial condyle (styloid notch) of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "radial condyle width" EXACT [] synonym: "radial notch breadth" EXACT [] synonym: "radius breadth of the radial condyle (M11)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "radius lateral distal condyle breadth" EXACT [] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:7500078 ! styloid process of radius relationship: characteristic_of UBERON:7500078 ! styloid process of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001162 name: ulnar condyle breadth def: "The length of the ulnar codyle (ulnar notch) of a radius along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "medial distal condyle breadth" EXACT [] synonym: "radius breadth of the ulnar condyle (M12)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "ulnar condyle width" EXACT [] synonym: "ulnar notch breadth" EXACT [] is_a: OBA:0002374 ! radius bone size is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:7500079 ! ulnar notch of radius relationship: characteristic_of UBERON:7500079 ! ulnar notch of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001163 name: patella length def: "The length of a patella along the proximal-distal axis." [ISBN:9780873659505] synonym: "patella greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002386 ! patella size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002446 ! patella relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001164 name: patella breadth def: "The length of a patella along th medial-lateral axis." [ISBN:9780873659505] synonym: "patella greatest breadth (GB)" RELATED [ISBN:9780873659505] synonym: "patella width" EXACT [] is_a: OBA:0002386 ! patella size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0002446 ! patella relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001165 name: obsolete scapula lateral depth def: "OBSOLETE The length on the lateral edge of a scapula along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: does not exist relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001166 name: secondary molar tooth 1 occlusal surface width synonym: "molar tooth 1 length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018376 ! molar tooth 1 relationship: characteristic_of UBERON:0018376 ! molar tooth 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: dc-description "The length of the occlusal surface of a molar tooth 1 along the medial-lateral axis." xsd:string {xref="https://orcid.org/0000-0003-2699-3066"} property_value: editor_note "need to add secondary molar tooth 1" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001167 name: obsolete upper molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a upper molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 1" xsd:string property_value: editor_note "need to add upper molar tooth 1" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001169 [Term] id: FOVT:0001168 name: obsolete lower molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add lower molar tooth 1" xsd:string property_value: editor_note "need to add secondary molar tooth 1" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001171 [Term] id: FOVT:0001169 name: upper secondary molar tooth 1 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1 length ML" EXACT [] is_a: FOVT:0001166 ! secondary molar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001170 name: obsolete upper primary molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001171 name: lower secondary molar tooth 1 occlusal surface width def: "The length of the occlusal surface of a lower secondary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1 length ML" EXACT [] is_a: FOVT:0001166 ! secondary molar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001172 name: obsolete lower primary molar tooth 1 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1 length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001173 name: secondary molar tooth 1 occlusal surface length def: "The length of the occlusal surface of a molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0018376 ! molar tooth 1 relationship: characteristic_of UBERON:0018376 ! molar tooth 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 1" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001174 name: obsolete upper molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] comment: redundant synonym: "upper molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 1" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001176 [Term] id: FOVT:0001175 name: obsolete lower molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of lower molar tooth 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] comment: redundant synonym: "lower molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 1" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001178 [Term] id: FOVT:0001176 name: upper secondary molar tooth 1 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001173 ! secondary molar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001177 name: obsolete upper primary molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001178 name: lower secondary molar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001173 ! secondary molar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001179 name: obsolete lower primary molar tooth 1 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 1 along the anterior-posterior axis." [] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001180 name: secondary molar tooth 2 occlusal surface width def: "The length of the occlusal surface of a molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 2 occlusal surface length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018606 ! molar tooth 2 relationship: characteristic_of UBERON:0018606 ! molar tooth 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 2" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001181 name: obsolete upper molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 2" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001183 [Term] id: FOVT:0001182 name: obsolete lower molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 2" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001185 [Term] id: FOVT:0001183 name: upper secondary molar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001180 ! secondary molar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001184 name: obsolete upper primary molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper secondary molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001185 name: lower secondary molar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower secondary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001180 ! secondary molar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001186 name: obsolete lower primary molar tooth 2 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 2 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001187 name: secondary molar tooth 2 occlusal surface length def: "The length of the occlusal surface a molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 2 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0018606 ! molar tooth 2 relationship: characteristic_of UBERON:0018606 ! molar tooth 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 2" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001188 name: obsolete upper molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 2" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001190 [Term] id: FOVT:0001189 name: obsolete lower molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 2" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001192 [Term] id: FOVT:0001190 name: upper secondary molar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001187 ! secondary molar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001191 name: obsolete upper primary molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper primary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001192 name: lower secondary molar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001187 ! secondary molar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001193 name: obsolete lower primary molar tooth 2 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower primary molar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 2 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001194 name: secondary molar tooth 3 occlusal surface width def: "The length of the occlusal surface of molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 3 occlusal surface length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018377 ! molar tooth 3 relationship: characteristic_of UBERON:0018377 ! molar tooth 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001195 name: obsolete upper molar tooth 3 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 3 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001197 [Term] id: FOVT:0001196 name: obsolete lower molar tooth 3 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 3 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001199 [Term] id: FOVT:0001197 name: upper secondary molar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001194 ! secondary molar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001198 name: DEPRECATED upper primary molar tooth 3 occlusal surface width comment: not a tooth is_obsolete: true [Term] id: FOVT:0001199 name: lower secondary molar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower secondary molar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 3 occlusal length ML" EXACT [] is_a: FOVT:0001194 ! secondary molar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001200 name: secondary molar tooth 3 occlusal surface length def: "The length of the occlusal surface of a molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 3 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0018377 ! molar tooth 3 relationship: characteristic_of UBERON:0018377 ! molar tooth 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 1" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001201 name: obsolete upper molar tooth 3 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 3 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001203 [Term] id: FOVT:0001202 name: obsolete lower molar tooth 3 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 3 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001204 [Term] id: FOVT:0001203 name: upper secondary molar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001200 ! secondary molar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001204 name: lower secondary molar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001200 ! secondary molar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001205 name: secondary molar tooth 4 occlusal surface width def: "The length of the occlusal surface of molar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 4 occlusal surface length ML" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:7500055 ! molar tooth 4 relationship: characteristic_of UBERON:7500055 ! molar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001206 name: obsolete upper molar tooth 4 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 4 along the medial-lateral surface." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 4 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001208 [Term] id: FOVT:0001207 name: obsolete lower molar tooth 4 occlusal surface width def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 4 occlusal surface length ML" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001209 [Term] id: FOVT:0001208 name: upper secondary molar tooth 4 occlusal surface width def: "The length of the occlusal surface of an upper secondary molar tooth 4 along the medial-lateral axis." [] synonym: "upper secondary molar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001205 ! secondary molar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001209 name: lower secondary molar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower secondry molar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001205 ! secondary molar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001210 name: secondary molar tooth 4 occlusal surface length def: "The length of the occlusal surface of a molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 4 occlusal surface length AP" EXACT [] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:7500055 ! molar tooth 4 relationship: characteristic_of UBERON:7500055 ! molar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001211 name: obsolete upper molar tooth 4 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of an upper molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "upper molar tooth 4 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001213 [Term] id: FOVT:0001212 name: obsolete lower molar tooth 4 occlusal surface length def: "OBSOLETE. The length of the occlusal surface of a lower molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: redundant synonym: "lower molar tooth 4 occlusal surface length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001214 [Term] id: FOVT:0001213 name: upper secondary molar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper secondary molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001210 ! secondary molar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001214 name: lower secondary molar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower secondary molar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001210 ! secondary molar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001215 name: premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 1 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018294 ! premolar 1 relationship: characteristic_of UBERON:0018294 ! premolar 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001216 name: upper premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width intersection_of: FOVT:0001215 ! premolar tooth 1 occlusal surface width intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001217 name: lower premolar tooth 1 occlusal suface width def: "The length of the occlusal surface of a lower premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001215 ! premolar tooth 1 occlusal surface width intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001218 name: upper secondary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001219 name: upper primary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface or an upper primary premolar 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001220 name: lower secondary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001221 name: lower primary premolar tooth 1 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 1 occlusal surface length ML" EXACT [] is_a: FOVT:0001215 ! premolar tooth 1 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001222 name: premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 1 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0018294 ! premolar 1 relationship: characteristic_of UBERON:0018294 ! premolar 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001223 name: upper premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001224 name: lower premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001222 ! premolar tooth 1 occlusal surface length intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001225 name: upper secondary premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001223 ! upper premolar tooth 1 occlusal surface length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001226 name: lower secondary premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 1 occlusal tooth length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001227 name: lower primary premolar tooth 1 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 1 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 1 occlusal surface length AP" EXACT [] is_a: FOVT:0001222 ! premolar tooth 1 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001228 name: premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 2 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018640 ! premolar 2 relationship: characteristic_of UBERON:0018640 ! premolar 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001229 name: upper premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width intersection_of: FOVT:0001228 ! premolar tooth 2 occlusal surface width intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001230 name: lower premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001228 ! premolar tooth 2 occlusal surface width intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001231 name: upper secondary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001232 name: upper primary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of an upper primary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001233 name: lower secondary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001234 name: lower primary premolar tooth 2 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 2 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 2 occlusal surface length ML" EXACT [] is_a: FOVT:0001228 ! premolar tooth 2 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001235 name: premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 2 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0018640 ! premolar 2 relationship: characteristic_of UBERON:0018640 ! premolar 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001236 name: upper premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 2 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length intersection_of: FOVT:0001235 ! premolar tooth 2 occlusal surface length intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001237 name: lower premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001235 ! premolar tooth 2 occlusal surface length intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001238 name: upper secondary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001239 name: upper primary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 2 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001240 name: lower secondary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 2 occlusal surface along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001241 name: lower primary premolar tooth 2 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 2 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 2 occlusal surface length AP" EXACT [] is_a: FOVT:0001235 ! premolar tooth 2 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001242 name: premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 3 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:7500056 ! premolar 3 relationship: characteristic_of UBERON:7500056 ! premolar 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001243 name: upper premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width intersection_of: FOVT:0001242 ! premolar tooth 3 occlusal surface width intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001244 name: lower premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001242 ! premolar tooth 3 occlusal surface width intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001245 name: upper secondary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001246 name: upper primary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of an upper primary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001247 name: lower secondary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001248 name: lower primary premolar tooth 3 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 3 occlusal surface length ML" EXACT [] is_a: FOVT:0001242 ! premolar tooth 3 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001249 name: premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 3 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:7500056 ! premolar 3 relationship: characteristic_of UBERON:7500056 ! premolar 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001250 name: upper premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 3 along the anterior-posterior axis." [] synonym: "upper premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length intersection_of: FOVT:0001249 ! premolar tooth 3 occlusal surface length intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001251 name: lower premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001249 ! premolar tooth 3 occlusal surface length intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001252 name: upper secondary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondry premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001253 name: upper primary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001254 name: lower secondary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001255 name: lower primary premolar tooth 3 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 3 along the anterior-posterior reference." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 3 occlusal surface length AP" EXACT [] is_a: FOVT:0001249 ! premolar tooth 3 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001256 name: premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 4 occlusal surface length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018647 ! premolar tooth 4 relationship: characteristic_of UBERON:0018647 ! premolar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001257 name: upper premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width intersection_of: FOVT:0001256 ! premolar tooth 4 occlusal surface width intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001258 name: lower premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001256 ! premolar tooth 4 occlusal surface width intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001259 name: upper secondary premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001260 name: upper primary premolar tooth 4 occlusal surface width def: "The length of the occlusal surfce of an upper primary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001261 name: lower secondary premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondry premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001262 name: lower primary premolar tooth 4 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 4 occlusal surface length ML" EXACT [] is_a: FOVT:0001256 ! premolar tooth 4 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001263 name: premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 4 along the anterior-posterior surface." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 4 occlusal surface length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0018647 ! premolar tooth 4 relationship: characteristic_of UBERON:0018647 ! premolar tooth 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001264 name: upper premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length intersection_of: FOVT:0001263 ! premolar tooth 4 occlusal surface length intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001265 name: lower premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001263 ! premolar tooth 4 occlusal surface length intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001266 name: upper secondary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001267 name: upper primary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001268 name: lower secondary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower secondary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001269 name: lower primary premolar tooth 4 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 4 occlusal surface length AP" EXACT [] is_a: FOVT:0001263 ! premolar tooth 4 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001270 name: premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 4 length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018646 ! premolar tooth 5 relationship: characteristic_of UBERON:0018646 ! premolar tooth 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001271 name: upper premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of an upper premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width intersection_of: FOVT:0001270 ! premolar tooth 5 occlusal surface width intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001272 name: lower premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a lower premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 5 occlusal suface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001270 ! premolar tooth 5 occlusal surface width intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001273 name: upper secondary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of an upper secondary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001274 name: upper primary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of an upper primary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001275 name: lower secondary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a lower secondary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001276 name: lower primary premolar tooth 5 occlusal surface width def: "The length of the occlusal surface of a lower primary premolar tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 5 occlusal surface length ML" EXACT [] is_a: FOVT:0001270 ! premolar tooth 5 occlusal surface width is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001277 name: premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 5 occlusal surfce length AP" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0018646 ! premolar tooth 5 relationship: characteristic_of UBERON:0018646 ! premolar tooth 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001278 name: upper premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of an upper premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length intersection_of: FOVT:0001277 ! premolar tooth 5 occlusal surface length intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001279 name: lower premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a lower premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001277 ! premolar tooth 5 occlusal surface length intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001280 name: upper secondary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of an upper secondary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001281 name: upper primary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of an upper primary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001282 name: lower secondary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001283 name: lower primary premolar tooth 5 occlusal surface length def: "The length of the occlusal surface of a lower primary premolar tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 5 occlusal surface length AP" EXACT [] is_a: FOVT:0001277 ! premolar tooth 5 occlusal surface length is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001284 name: upper tooth row length def: "The length of an upper tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper tooth row length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length intersection_of: FOVT:0000030 ! tooth row length intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001285 name: lower tooth row length def: "The length of a lower tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower tooth row length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0000030 ! tooth row length intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001286 name: canine tooth crown height def: "The height of a canine tooth crown along the superior-anterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "cuspid crown height" EXACT [] is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0002100 ! tooth morphology trait is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001287 name: lower canine tooth crown height def: "The height of a lower canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower cuspid crown height" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018622 ! lower canine tooth relationship: characteristic_of UBERON:0018622 ! lower canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001288 name: upper canine tooth crown height def: "The height of an upper canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper cuspid crown height" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018621 ! upper canine tooth relationship: characteristic_of UBERON:0018621 ! upper canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001289 name: upper secondary canine tooth crown height def: "The height of an upper secondary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper seconday cuspid crown height" EXACT [] is_a: FOVT:0001288 ! upper canine tooth crown height is_a: FOVT:0001293 ! secondary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018561 ! upper secondary canine tooth relationship: characteristic_of UBERON:0018561 ! upper secondary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001290 name: lower secondary canine tooth crown height def: "The height of a lower secondary canine tooth crown along the superior-inferior axis." [ISBN:9780873659505] comment: The measurement number and genus from von den Driesch (1979): 21 Canis, 17 Ursus. {xref="ISBN:9780873659505"} synonym: "height of the canine" EXACT [ISBN:9780873659505] synonym: "lower secondary cuspid crown height" EXACT [] is_a: FOVT:0001287 ! lower canine tooth crown height is_a: FOVT:0001293 ! secondary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018562 ! lower secondary canine tooth relationship: characteristic_of UBERON:0018562 ! lower secondary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001291 name: upper primary canine tooth crown height def: "The height of an upper primary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary cuspid crown height" EXACT [] is_a: FOVT:0001288 ! upper canine tooth crown height is_a: FOVT:0001294 ! primary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018597 ! upper primary canine tooth relationship: characteristic_of UBERON:0018597 ! upper primary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001292 name: lower primary canine tooth crown height def: "The height of a lower primary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary cuspid crown height" EXACT [] is_a: FOVT:0001287 ! lower canine tooth crown height is_a: FOVT:0001294 ! primary canine tooth crown height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018598 ! lower primary canine tooth relationship: characteristic_of UBERON:0018598 ! lower primary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001293 name: secondary canine tooth crown height def: "The height of a secondary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "secondary cuspid crown height" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018584 ! secondary canine tooth relationship: characteristic_of UBERON:0018584 ! secondary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001294 name: primary canine tooth crown height def: "The height of a primary canine tooth crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "primary cuspid crown height" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018583 ! primary canine tooth relationship: characteristic_of UBERON:0018583 ! primary canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001295 name: premolar tooth row length def: "The length of the occlusal surface of premolars along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0003215 ! premolar tooth morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001296 name: molar tooth row length def: "The length of the occlusal surface of molars along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001300 ! upper molar tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001297 name: upper premolar tooth row length def: "The length of an upper premolar tooth row along the anterior-posterior length." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0000030 ! tooth row length is_a: OBA:0003215 ! premolar tooth morphology is_a: OBA:VT0000454 ! jaw morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001298 name: lower premolar tooth row length def: "The length of a lower premolar tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001285 ! lower tooth row length is_a: OBA:0002710 ! premolar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001299 name: lower molar tooth row length def: "The length of a lower molar tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001285 ! lower tooth row length is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001300 name: upper molar tooth row length def: "The length of an upper tooth row along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0000030 ! tooth row length is_a: OBA:VT0002689 ! molar morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001301 name: canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of a canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "canine tooth diameter AP" EXACT [] synonym: "cuspid diameter AP" EXACT [] synonym: "cuspid tooth anterior-posterior diameter" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003674 ! cuspid relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001302 name: upper canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of an upper canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper canine tooth diameter AP" EXACT [] synonym: "upper cuspid anterior-posterior diameter" EXACT [] synonym: "upper cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001303 name: lower canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of a lower canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower canine tooth diameter AP" EXACT [] synonym: "lower cuspid anterior-posterior diameter" EXACT [] synonym: "lower cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001304 name: upper secondary canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of an upper secondary canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: The measurement number and genus from von den Driesch (1979): 21 Sus {xref="ISBN:9780873659505"} synonym: "greatest diameter of the canine alveolus" EXACT [] synonym: "upper secondary canine tooth diameter AP" EXACT [] synonym: "upper secondary cuspid anterior-posterior diameter" EXACT [ISBN:9780873659505] synonym: "upper secondary cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001305 name: lower secondary canine anterior-posterior diameter def: "The diameter at the base (alveoli) of a lower secondary canine tooth along the anterior-posterior diameter." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondaray canine tooth diameter AP" EXACT [] synonym: "lower secondry cuspid anterior-posterior diameter" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001306 name: upper primary canine anterior-posterior diameter def: "The diameter at the base (alveoli) of an upper primary canine tooth along the anterior-posterior diameter." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary canine tooth diameter AP" EXACT [] synonym: "upper primary cuspid anterior-posterior diameter" EXACT [] synonym: "upper primary cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:0002703 ! primary dentition size relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001307 name: lower primary canine tooth anterior-posterior diameter def: "The diameter at the base (alveoli) of a lower primary canine tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary canine tooth diameter AP" EXACT [] synonym: "lower primary cuspid anterior-posterior diameter" EXACT [] synonym: "lower primary cuspid diameter AP" EXACT [] is_a: FOVT:0001301 ! canine tooth anterior-posterior diameter is_a: OBA:0002703 ! primary dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001308 name: canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "canine tooth diameter ML" EXACT [] synonym: "cuspid diameter ML" EXACT [] synonym: "cuspid medial-lateral diameter" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003674 ! cuspid relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001309 name: upper canine tooth medial-lateral diameter def: "The diameter at a base (alveoli) of an upper canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: The measurement number and genus from von den Driesch (1979): 27 Felis synonym: "cuspid diameter ML" EXACT [] synonym: "upper canine tooth diameter AP" EXACT [] synonym: "upper cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001310 name: lower canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a lower canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower canine tooth diameter ML" EXACT [] synonym: "lower cuspid diameter ML" EXACT [] synonym: "lower cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001311 name: upper secondary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of an upper secondary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] comment: The measurement number and genus from von den Driesch (1979): 27 Felis {xref="ISBN:9780873659505"} synonym: "breadth of the canine alveoli" EXACT [ISBN:9780873659505] synonym: "upper secondary canine tooth diameter ML" EXACT [] synonym: "upper secondary cuspid diameter ML" EXACT [] synonym: "upper secondary cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001312 name: lower secondary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a lower secondary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary canine tooth diameter ML" EXACT [] synonym: "lower secondary cuspid diameter ML" EXACT [] synonym: "lower secondary cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001313 name: upper primary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of an upper primary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary canine tooth diameter ML" EXACT [] synonym: "upper primary cuspid diameter ML" EXACT [] synonym: "upper primary cuspid medial-lateral diameter" EXACT [] is_a: OBA:1000112 ! tooth size is_a: OBA:1000335 ! cuspid quality is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0018583 ! primary canine tooth relationship: characteristic_of UBERON:0018621 ! upper canine tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001314 name: lower primary canine tooth medial-lateral diameter def: "The diameter at the base (alveoli) of a lower primary canine tooth along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary canine tooth diameter ML" EXACT [] synonym: "lower primary cuspid diameter ML" EXACT [] synonym: "lower primary cuspid medial-lateral diameter" EXACT [] is_a: FOVT:0001308 ! canine tooth medial-lateral diameter is_a: OBA:0002703 ! primary dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add \"alveolar process of mandible\" for logical definition" xsd:string property_value: editor_note "need to add \"canine tooth size trait\" for this term to be nested under" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001315 name: upper left tooth row length def: "The length of a tooth row on the left side along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper left tooth row length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001316 name: upper right tooth row length def: "The length of an upper tooth row on the right side along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper right tooth row length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001317 name: molar tooth 1-2 length def: "The length of molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001318 name: molar tooth 1-3 length def: "The length of molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001319 name: molar tooth 1-4 length def: "The length of molar teeth 1-4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "molar tooth 1-4 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001320 name: upper molar tooth 1-2 length def: "The length of upper molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001321 name: lower molar tooth 1-2 length def: "The length of lower molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001322 name: upper secondary molar tooth 1-2 length def: "The length of upper secondary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001176 ! upper secondary molar tooth 1 occlusal surface length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001323 name: lower secondary molar tooth 1-2 length def: "The length of lower secondary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1-2 length AP" EXACT [] is_a: FOVT:0001345 ! lower secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001324 name: obsolete upper primary molar tooth 1-2 length def: "OBSOLETE. The length of upper primary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1-2 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001325 name: obsolete lower primary molar tooth 1-2 length def: "OBSOLETE. The length of lower primary molar teeth 1-2 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1-2 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001326 name: upper molar tooth 1-3 length def: "The length of upper molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001327 name: lower molar tooth 1-3 length def: "The length of lower molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001328 name: upper secondary molar tooth 1-3 length def: "The length of upper secondary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001176 ! upper secondary molar tooth 1 occlusal surface length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001329 name: lower secondary molar tooth 1-3 length def: "The length of lower secondary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary molar tooth 1-3 length AP" EXACT [] is_a: FOVT:0001345 ! lower secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001330 name: obsolete upper primary molar tooth 1-3 length def: "OBSOLETE. The length of upper primary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "upper primary molar tooth 1-3 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001331 name: obsolete lower primary molar tooth 1-3 length def: "OBSOLETE. The length of lower primary molar teeth 1-3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] comment: no primary molars, term should not exist synonym: "lower primary molar tooth 1-3 length AP" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001332 name: upper molar tooth 1-4 length def: "The length of upper molar teeth 1-4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper molar tooth 1-4 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001333 name: lower molar tooth 1-4 length def: "The length of lower molar teeth 1-4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower molar tooth 1-4 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001334 name: premolar tooth 4 to molar tooth 3 length def: "The length of premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar 4 to molar 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001335 name: upper premolar tooth 4 to molar tooth 3 length def: "The length of upper premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [] synonym: "upper premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001336 name: lower premolar tooth 4 to molar tooth 3 length def: "The length of lower premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001337 name: upper secondary premolar tooth 4 to molar tooth 3 length def: "The length of upper secondary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001344 ! upper secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001338 name: upper primary premolar tooth 4 to molar tooth 3 length def: "The length of upper primary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper primary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001339 name: lower secondary premolar tooth 4 to molar tooth 3 length def: "The length of lower secondary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0001300 ! upper molar tooth row length is_a: FOVT:0001345 ! lower secondary canine tooth to premolar tooth 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001340 name: lower primary premolar tooth 4 to molar tooth 3 length def: "The length of lower primary premolar tooth 4 to molar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower primary premolar tooth 4 to molar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001341 name: canine tooth to premolar tooth 3 length def: "The length of canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "cuspid to premolar tooth 3 length" EXACT [] synonym: "cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001342 name: upper canine tooth to premolar tooth 3 length def: "The length of upper canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "upper cuspid to premolar tooth 3 length" EXACT [] synonym: "upper cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0001284 ! upper tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001343 name: lower canine tooth to premolar tooth 3 length def: "The length of lower canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "lower cuspid to premolar tooth 3 length" EXACT [] synonym: "lower cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0001285 ! lower tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001344 name: upper secondary canine tooth to premolar tooth 3 length def: "The length of upper secondary canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper secondary canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "upper secondary cuspid to premolar tooth 3 length AP" EXACT [] synonym: "upper secondary cuspid tooth to premolar tooth 3 length" EXACT [] is_a: FOVT:0000030 ! tooth row length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001345 name: lower secondary canine tooth to premolar tooth 3 length def: "The length of lower secondary canine tooth to premolar tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower secondary canine tooth to premolar tooth 3 length AP" EXACT [] synonym: "lower secondary cuspid to premolar tooth 3 length" EXACT [] synonym: "lower secondary cuspid to premolar tooth 3 length AP" EXACT [] is_a: FOVT:0000030 ! tooth row length is_a: OBA:VT0000458 ! mandible morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001346 name: diastema between central incisors length def: "The length of diastema between central incisors along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0035115 ! diastema between central incisors relationship: characteristic_of UBERON:0035115 ! diastema between central incisors relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001347 name: diastema between lower central incisors length def: "The length of diastema between lower central incisors along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001346 ! diastema between central incisors length is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001346 ! diastema between central incisors length intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001348 name: upper secondary premolar tooth 3 crown height def: "The height of an upper secondary premolar tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001349 name: upper secondary premolar tooth 4 crown height def: "The length of an upper secondary premolar tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0002710 ! premolar tooth size is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0000119 ! height relationship: characteristic_of UBERON:0016452 ! upper secondary premolar tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001350 name: lower premolar tooth 3 anterior width def: "The length of the anterior side of a lower premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 anterior length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001351 name: lower premolar tooth 3 posterior width def: "The length of the posterior side of a lower premolar tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower premolar tooth 3 posterior length ML" EXACT [] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001354 name: metacarpal bone of digit 3 diaphysis depth def: "The length of the diaphysis of a metacarpal bone of digit 3 along the anterior-posterior axis" [ISBN:9004086161\, 9789004086166] synonym: "metacarpal III smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] synonym: "third metacarpal depth of the diaphysis at the level of M3 (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002097 ! metacarpal bone diaphysis depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001355 name: metacarpal bone of digit 3 diaphysis breadth def: "The length of the shaft of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal III smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third metacarpal miniaml breadth (near the middle of the body) (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002102 ! metacarpal bone diaphysis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001356 name: metacarpal bone of digit 3 proximal articular breadth def: "The length of the articular surface on the proximal end of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal III distal breadth (Bd)" RELATED [ISBN:9780873659505] synonym: "metacarpal III proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001357 name: metacarpal bone of digit 3 distal articular breadth def: "The length of the articular surface on the distal end of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001358 name: metacarpal bone of digit 3 lateral condyle depth def: "The length of the lateral condyle on the distal end of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal minimal depth of the lateral condyle (13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001359 name: pelvis length def: "The length of a pelvis along the proximal-distal axis." [ISBN:9780873659505] synonym: "pelvis greatest length of one half (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0007830 ! pelvic girdle bone/zone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001360 name: acetabulum length (including the lip) def: "The length of an acetabulum along the upper-lower axis." [ISBN:9780873659505] comment: This measurement includes the lip of the acetabulum. synonym: "length of the acetabulum including the lip (LA)" RELATED [ISBN:9780873659505] is_a: OBA:0002413 ! pelvic girdle bone/zone size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001361 name: acetabulum length (to the rim) def: "The length of an acetabulum up to the rim of an acetabulum along the upper-lower axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This measurement does not include the lip. synonym: "diameter of the acetabulum (M1)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "length of the acetabulum to the rim (LAR)" RELATED [ISBN:9780873659505] is_a: OBA:0002413 ! pelvic girdle bone/zone size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001362 name: pubic symphysis length def: "The length of a pubic symphysis along the proximal-distal axis." [ISBN: 9780873659505] comment: This is only measured when the two halves of the pubis are fused. synonym: "length of the symphysis (LS)" RELATED [ISBN:9780873659505] is_a: FOVT:0001359 ! pelvis length is_a: OBA:0002395 ! pubic symphysis size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003699 ! pubic symphysis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001363 name: ilial shaft height def: "The length of an ilial shaft along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "smallest height of the shaft of ilium (SH)" RELATED [ISBN:9780873659505] is_a: FOVT:0001359 ! pelvis length is_a: OBA:0002162 ! ilium size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:3000774 ! ilial shaft relationship: characteristic_of UBERON:3000774 ! ilial shaft relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001364 name: ilial shaft breadth def: "The length of an ilial shaft along the medial-lateral axis." [ISBN:9780873659505] synonym: "ilial shaft width" EXACT [] synonym: "smallest breadth of the shaft of ilium (SB)" RELATED [ISBN:9780873659505] is_a: OBA:0002162 ! ilium size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:3000774 ! ilial shaft relationship: characteristic_of UBERON:3000774 ! ilial shaft relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001365 name: scapula lateral breadth def: "The length of the articular process on the lateral end of a scapula along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is measured from the articular process. synonym: "scapula geatest length of the processus articularis (glenoid process) (GLP)" RELATED [ISBN:9780873659505] synonym: "scapula maximal breadth of the articular process (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001157 ! scapula depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001366 name: obsolete right testis length def: "OBSOLETE The length of a testis on the right side." [https://orcid.org/0000-0003-2699-3066] comment: made an error, made new term synonym: "testis length" RELATED [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2022-05-05T23:24:47Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001058 [Term] id: FOVT:0001367 name: obsolete right testis length comment: made error, term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2022-05-05T23:27:11Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001058 [Term] id: FOVT:0001368 name: testis width def: "The width of a testis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001369 ! gonad width is_a: OBA:VT0001148 ! testes size trait intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000473 ! testis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001369 name: gonad width def: "The width of a gonad." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0002017 ! gonad size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000991 ! gonad relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001370 name: obsolete right ovary length def: "OBSOLETE The length of an ovary on the right side." [https://orcid.org/0000-0003-2699-3066] comment: didn't realize the term already existed synonym: "ovary length" RELATED [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2022-05-05T23:45:43Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0001063 [Term] id: FOVT:0001371 name: ovary width def: "The width of an ovary." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001369 ! gonad width is_a: OBA:VT0001127 ! ovary size trait intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000992 ! ovary relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001372 name: ilial shaft circumference def: "The circumference of an ilial shaft." [ISBN:9780873659505] synonym: "smallest circumference of the shaft of ilium (SC)" RELATED [ISBN:9780873659505] is_a: OBA:0002162 ! ilium size is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:3000774 ! ilial shaft relationship: characteristic_of UBERON:3000774 ! ilial shaft relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001373 name: foramen obturatum length def: "The length of a formaen obturatum along the proximal-distal axis." [ISBN:9780873659505] synonym: "inner foramen obturatum length (LFo)" RELATED [ISBN:9780873659505] is_a: FOVT:0001359 ! pelvis length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0006803 ! obturator foramen relationship: characteristic_of UBERON:0006803 ! obturator foramen relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001374 name: tubera coxarum breadth def: "The length of a tubera coxarum." [ISBN:9780873659505] synonym: "greatest breadth across the tubera coxarum (GBTc)" RELATED [ISBN:9780873659505] synonym: "tubera coxarum width" EXACT [] is_a: OBA:0002413 ! pelvic girdle bone/zone size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001375 name: acetabula breadth def: "The length of an acetabula along the medial-lateral axis." [ISBN:9780873659505] synonym: "acetablua width" EXACT [] synonym: "greatest breadth across the acetabula (GBA)" RELATED [ISBN:9780873659505] is_a: OBA:0002412 ! acetabular part of hip bone size is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001269 ! acetabular part of hip bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001376 name: tubera ischiadica breadth def: "The length of an ischial tuberosity along the medial-lateral axis." [ISBN:9780873659505] synonym: "greatest breadth across the tubera ischiadica (GBTi)" RELATED [ISBN:9780873659505] synonym: "tubera ischiadica width" EXACT [] is_a: FOVT:0001359 ! pelvis length is_a: OBA:0002391 ! ischium size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0034983 ! ischial tuberosity relationship: characteristic_of UBERON:0034983 ! ischial tuberosity relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001377 name: ischia breadth def: "The length across both ischia along the medial-lateral axis." [ISBN:9780873659505] synonym: "ischia width" EXACT [] synonym: "smallest breadth across the bodies of the ischia (SBI)" RELATED [ISBN:9780873659505] is_a: OBA:0002391 ! ischium size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001274 ! ischium relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001378 name: calcaneus lateral depth def: "The length of the lateral side of a calcaneus along the proximal-distal axis." [https://ethnobiology.org/sites/default/files/pdfs/JoE/7-1/Purdue1987.pdf] synonym: "lateral depth of the calcaneum (CALD)" RELATED [https://ethnobiology.org/sites/default/files/pdfs/JoE/7-1/Purdue1987.pdf] is_a: OBA:0003330 ! calcaneus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001379 name: forearm length def: "The length of a forearm." [DOI:10.1080/00445096.1965.11447303] comment: This is measured from the end of the ulna to the end of the carpus. {xref="DOI:10.1080/00445096.1965.11447303"} synonym: "fore-arm length" EXACT [] is_a: OBA:VT0010023 ! forelimb length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001380 name: secondary molar tooth 1 crown height def: "The height of a secondary molar tooth 1 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: need to add secondary molar tooth 1 is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018376 ! molar tooth 1 relationship: characteristic_of UBERON:0018376 ! molar tooth 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001381 name: upper secondary molar tooth 1 crown height def: "The height of an upper molar tooth 1 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: need to add secondary molar tooth 1 synonym: "M1 crown height" EXACT [] is_a: FOVT:0001380 ! secondary molar tooth 1 crown height intersection_of: FOVT:0001380 ! secondary molar tooth 1 crown height intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001382 name: lower secondary molar tooth 1 crown height def: "The height of a lower molar tooth 1 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: need to add secondary molar tooth 1 synonym: "m1 crown height" EXACT [] is_a: FOVT:0001380 ! secondary molar tooth 1 crown height is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001380 ! secondary molar tooth 1 crown height intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001383 name: secondary molar tooth 2 crown height def: "The height of a secondary molar tooth 2 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018606 ! molar tooth 2 relationship: characteristic_of UBERON:0018606 ! molar tooth 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 2" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001384 name: lower secondary molar tooth 2 crown height def: "The height of a lower secondary molar tooth 2 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "m2 crown height" EXACT [] is_a: FOVT:0001383 ! secondary molar tooth 2 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001385 name: upper secondary molar tooth 2 crown height def: "The height of an upper secondary molar tooth 2 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "M2 crown height" EXACT [] is_a: FOVT:0001383 ! secondary molar tooth 2 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001386 name: secondary molar tooth 3 crown height def: "The height of a secondary molar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018377 ! molar tooth 3 relationship: characteristic_of UBERON:0018377 ! molar tooth 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add secondary molar tooth 3 to logical definition" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001387 name: lower secondary molar tooth 3 crown height def: "The height of a lower secondary molar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "m3 crown height" EXACT [] is_a: FOVT:0001386 ! secondary molar tooth 3 crown height is_a: OBA:VT0000458 ! mandible morphology trait intersection_of: FOVT:0001386 ! secondary molar tooth 3 crown height intersection_of: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001388 name: upper secondary molar tooth 3 crown height def: "The height of an upper secondary molar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "M3 crown height" EXACT [] is_a: FOVT:0001386 ! secondary molar tooth 3 crown height intersection_of: FOVT:0001386 ! secondary molar tooth 3 crown height intersection_of: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001389 name: lower secondary molar tooth 1 trigonid width def: "The width of a lower secondary molar tooth 1 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001390 name: lower secondary molar tooth 1 trigonid length def: "The length of a lower secondary molar tooth 1 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001391 name: lower secondary molar tooth 1 talonid width def: "The width of a lower secondary molar tooth 1 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001392 name: lower secondary molar tooth 1 talonid length def: "The lenght of a lower secondary molar tooth 1 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001393 name: lower secondary molar tooth 2 trigonid width def: "The widht of a lower secondary molar tooth 2 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001394 name: lower secondary molar tooth 2 trigonid length def: "The length of a lower secondary molar tooth 2 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001395 name: lower secondary molar 2 talonid width def: "The widht of a lower secondary molar 2 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001396 name: lower secondary molar tooth 2 talonid length def: "The length of a lower secondary molar tooth 2 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001397 name: lower secondary molar tooth 3 trigonid width def: "The width of a lower secondary molar tooth 3 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001398 name: lower secondary molar tooth 3 trigonid length def: "The length of a lower secondary molar tooth 3 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001399 name: lower secondary molar tooth 3 talonid width def: "The width of a lower secondary molar tooth 3 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001400 name: lower secondary molar tooth 3 talonid length def: "The length of a lower secondary molar tooth 3 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001401 name: lower secondary molar tooth 4 trigonid width def: "The width of a lower secondary molar tooth 4 trigonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001402 name: lower secondary molar tooth 4 trigonid length def: "The length of a lower secondary molar tooth 4 trigonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001403 name: lower secondary molar tooth 4 talonid width def: "The width of a lower secondary molar tooth 4 talonid along the left-right axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001404 name: lower secondary molar tooth 4 talonid length def: "The length of a lower secondary molar tooth 4 talonid along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0004257 ! molar tooth size relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add talonid" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001405 name: premolar tooth 3 crown height def: "The height of a premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:0002710 ! premolar tooth size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:7500056 ! premolar 3 relationship: characteristic_of UBERON:7500056 ! premolar 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001406 name: upper premolar tooth 3 crown height def: "The height of an upper premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001407 name: lower premolar tooth 3 crown height def: "The height of a lower premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001408 name: obsolete upper secondary premolar tooth 3 crown height def: "OBSOLETE. The height of an upper secondary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] comment: term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001348 [Term] id: FOVT:0001409 name: lower secondary premolar tooth 3 crown height def: "The height of a secondary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001410 name: upper primary premolar tooth 3 crown height def: "The height of an upper primary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0002703 ! primary dentition size relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001411 name: lower primary premolar tooth 3 crown height def: "The height of a lower primary premolar tooth 3 crown along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: FOVT:0001405 ! premolar tooth 3 crown height is_a: OBA:0002703 ! primary dentition size is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001500 name: incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 1 (central incisor) tooth along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "central incisor anterior-posterior diameter" EXACT [] synonym: "central incisor diameter AP" EXACT [] synonym: "incisor 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0018551 ! central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001501 name: upper incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of an upper incisor tooth 1 (central incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "upper central incisor anterior-posterior diameter" EXACT [] synonym: "upper central incisor diameter AP" EXACT [] synonym: "upper incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000454 ! jaw morphology trait relationship: characteristic_of UBERON:0018603 ! upper central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001502 name: lower incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of a lower incisor tooth 1 (central incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "lower central incisor anterior-posterior diameter" EXACT [] synonym: "lower central incisor diameter AP" EXACT [] synonym: "lower incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0018601 ! lower central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001503 name: upper secondary incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 1 (central incisor) along the anterior-posterior axis." [] synonym: "I1 anterior-posterior diameter" EXACT [] synonym: "I1 diameter AP" EXACT [] synonym: "upper secondary central incisor anterior-posterior diameter" EXACT [] synonym: "upper secondary central incisor diameter AP" EXACT [] synonym: "upper secondary incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000454 ! jaw morphology trait relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018603 ! upper central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001504 name: lower secondary incisor tooth 1 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 1 (central incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i1 anterior-posterior diameter" EXACT [] synonym: "i1 diameter AP" EXACT [] synonym: "lower secondary central incisor anterior-posterior diameter" EXACT [] synonym: "lower secondary central incisor diameter AP" EXACT [] synonym: "lower secondary incisor tooth 1 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000454 ! jaw morphology trait is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018601 ! lower central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001505 name: incisor tooth 1 medial-lateral diameter def: "The diameter at the base of a incisor tooth 1 (central incisor) along the medial-lateral axis." [] synonym: "central incisor diameter ML" EXACT [] synonym: "central incisor medial-lateral diameter" EXACT [] synonym: "incisor tooth 1 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0018551 ! central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001506 name: upper secondary incisor tooth 1 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 1 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I1 diameter ML" EXACT [] synonym: "I1 medial-lateral diameter" EXACT [] synonym: "upper secondary central incisor diameter ML" EXACT [] synonym: "upper secondary central tooth medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 1 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018551 ! central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001507 name: lower secondary incisor tooth 1 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 1 (central incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i1 diameter ML" EXACT [] synonym: "i1 medial-lateral diameter" EXACT [] synonym: "lower secondary central incisor diameter ML" EXACT [] synonym: "lower secondary central incisor medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 1 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018551 ! central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001508 name: incisor tooth 1 crown height def: "The height of an incisor tooth 1 (central incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "central incisor crown height" EXACT [] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018551 ! central incisor tooth relationship: characteristic_of UBERON:0018551 ! central incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001509 name: upper secondary incisor tooth 1 crown height def: "The height of an upper secondary incisor tooth (central incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I1 crown height" EXACT [] synonym: "upper secondary central incisor crown height" EXACT [] is_a: FOVT:0001508 ! incisor tooth 1 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001510 name: lower secondary incisor tooth 1 crown height def: "The height of a lower secondary incisor tooth 1 (central incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i1 crown height" EXACT [] synonym: "lower secondary central incisor crown height" EXACT [] is_a: FOVT:0001508 ! incisor tooth 1 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001511 name: incisor tooth 2 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 2 (lateral incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 2 diameter AP" EXACT [] synonym: "lateral incisor tooth anterior-posterior diameter" EXACT [] synonym: "lateral incisor tooth diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001512 name: upper secondary incisor tooth 2 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 2 (lateral incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I2 anterior-posterior diameter" EXACT [] synonym: "I2 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 2 diameter AP" EXACT [] synonym: "upper secondary lateral incisor anterior-posterior diameter" EXACT [] synonym: "upper secondary lateral incisor diameter AP'has exact synonym'" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001513 name: lower secondary incisor tooth 2 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 2 (lateral incisor) along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i2 anterior-posterior diameter" EXACT [] synonym: "i2 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 2 diameter AP" EXACT [] synonym: "lower secondary lateral incisor anterior-posterior diameter" EXACT [] synonym: "lower secondary lateral incisor diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001514 name: incisor tooth 2 medial-lateral diameter def: "The diameter at the base of an incisor tooth 2 (lateral incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 2 diameter ML" EXACT [] synonym: "lateral incisor diameter ML'has exact synonym'" EXACT [] synonym: "lateral incisor medial-lateral diameter" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001515 name: upper secondary incisor tooth 2 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 2 (lateral incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I2 diameter ML" EXACT [] synonym: "I2 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 2 diameter ML" EXACT [] synonym: "upper secondary lateral incisor diameter ML" EXACT [] synonym: "upper secondary lateral incisor medial-lateral diameter" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001516 name: lower secondary incisor tooth 2 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 2 (lateral incisor) along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i2 diameter ML" EXACT [] synonym: "i2 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 2 diameter ML" EXACT [] synonym: "lower secondary lateral incisor diameter ML" EXACT [] synonym: "lower secondary lateral incisor medial-lateral diameter" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001517 name: incisor tooth 2 crown height def: "The height of an incisor tooth 2 (lateral incisor) along the superior-inferior axis." [] synonym: "lateral incisor crown height" EXACT [] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: characteristic_of UBERON:0018552 ! lateral incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001518 name: upper secondary incisor tooth 2 crown height def: "The height of an upper secondary incisor tooth 2 (lateral incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I2 crown height" EXACT [] synonym: "upper secondary lateral incisor crown height" EXACT [] is_a: FOVT:0001517 ! incisor tooth 2 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001519 name: lower secondary incisor tooth 2 crown height def: "The height of a lower secondary incisor tooth (lateral incisor) along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i2 crown height" EXACT [] synonym: "lower secondary lateral incisor crown height" EXACT [] is_a: FOVT:0001517 ! incisor tooth 2 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001520 name: incisor tooth 3 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 3 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001521 name: upper secondary incisor tooth 3 anterior-posteior diameter def: "The diameter of an upper secondary incisor tooth 3 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I3 anterior-posterior diameter" EXACT [] synonym: "I3 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 3 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001522 name: lower secondary incisor tooth 3 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 3 along the anterior-posterior axis." [] synonym: "i3 anterior-posterior diameter" EXACT [] synonym: "i3 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 3 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001523 name: incisor tooth 3 medial-lateral diameter def: "The diameter at the base of an incisor tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 3 diamter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001524 name: upper secondary incisor tooth 3 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I3 diameter ML" EXACT [] synonym: "I3 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 3 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001525 name: lower secondary incisor tooth 3 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 3 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i3 diameter ML" EXACT [] synonym: "i3 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 3 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001526 name: incisor tooth 3 crown height def: "The height of an incisor tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001527 name: upper secondary incisor tooth 3 crown height def: "The height of an upper secondary incisor tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I3 crown height" EXACT [] is_a: FOVT:0001526 ! incisor tooth 3 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001528 name: lower secondary incisor tooth 3 crown height def: "The height of a lower secondary incisor tooth 3 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i3 crown height" EXACT [] is_a: FOVT:0001526 ! incisor tooth 3 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 3" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001529 name: incisor tooth 4 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 4 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001530 name: upper secondary incisor tooth 4 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I4 anterior-posterior diameter" EXACT [] synonym: "I4 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 4 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001531 name: lower secondary incisor tooth 4 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 4 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i4 anterior-posterior diameter" EXACT [] synonym: "i4 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 4 diamter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001532 name: incisor tooth 4 medial-lateral diameter def: "The diameter at the base of an incisor tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 4 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001533 name: upper secondary incisor tooth 4 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I4 diameter ML" EXACT [] synonym: "I4 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 4 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001534 name: lower secondary incisor tooth 4 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 4 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i4 diameter ML" EXACT [] synonym: "i4 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 4 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001535 name: incisor tooth 4 crown height def: "The height of an incisor tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001536 name: upper secondary incisor tooth 4 crown height def: "The height of an upper secondary incisor tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I4 crown height" EXACT [] is_a: FOVT:0001535 ! incisor tooth 4 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001537 name: lower secondary incisor tooth 4 crown height def: "The height of a lower secondary incisor tooth 4 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i4 crown height" EXACT [] is_a: FOVT:0001535 ! incisor tooth 4 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 4" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001538 name: incisor tooth 5 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 5 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001539 name: upper secondary incisor tooth 5 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I5 anterior-posterior diameter" EXACT [] synonym: "I5 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 5 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001540 name: lower secondary incisor tooth 5 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 5 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i5 anterior-posterior diameter" EXACT [] synonym: "i5 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 5 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001541 name: incisor tooth 5 medial-lateral diameter def: "The diameter at the base of an incisor tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 5 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001542 name: upper secondary incisor tooth 5 medial-lateral diameter def: "The diamter at the base of an upper secondary incisor tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I5 diameter ML" EXACT [] synonym: "I5 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 5 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001543 name: lower secondary incisor tooth 5 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 5 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i5 diameter ML" EXACT [] synonym: "i5 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 5 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001544 name: incisor tooth 5 crown height def: "The height of an incisor tooth 5 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001545 name: upper secondary incisor tooth 5 crown height def: "The height of an upper secondary incisor tooth 5 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I5 crown height" EXACT [] is_a: FOVT:0001544 ! incisor tooth 5 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001546 name: lower secondary incisor tooth 5 crown height def: "The height of a lower secondary incisor tooth 5 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i5 crown height" EXACT [] is_a: FOVT:0001544 ! incisor tooth 5 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 5" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001547 name: incisor tooth 6 anterior-posterior diameter def: "The diameter at the base of an incisor tooth 6 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 6 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001548 name: upper secondary incisor tooth 6 anterior-posterior diameter def: "The diameter at the base of an upper secondary incisor tooth 6 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I6 anterior-posterior diameter" EXACT [] synonym: "I6 diameter AP" EXACT [] synonym: "upper secondary incisor tooth 6 diamter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001549 name: lower secondary incisor tooth 6 anterior-posterior diameter def: "The diameter at the base of a lower secondary incisor tooth 6 along the anterior-posterior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i6 anterior-posterior diameter" EXACT [] synonym: "i6 diameter AP" EXACT [] synonym: "lower secondary incisor tooth 6 diameter AP" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0000013 ! anterior-posterior axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001550 name: incisor tooth 6 medial-lateral diameter def: "The diameter at the base of an incisor tooth 6 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "incisor tooth 6 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001551 name: upper secondary incisor tooth 6 medial-lateral diameter def: "The diameter at the base of an upper secondary incisor tooth 6 along the medial-latearl axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I6 diameter ML" EXACT [] synonym: "I6 medial-lateral diameter" EXACT [] synonym: "upper secondary incisor tooth 6 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001552 name: lower secondary incisor tooth 6 medial-lateral diameter def: "The diameter at the base of a lower secondary incisor tooth 6 along the medial-lateral axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i6 diameter ML" EXACT [] synonym: "i6 medial-lateral diameter" EXACT [] synonym: "lower secondary incisor tooth 6 diameter ML" EXACT [] is_a: FOVT:0001556 ! incisor tooth diameter is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: follows_axis BSPO:0001001 ! medial-lateral axis property_value: editor_note "need to add alveolar ridge mandible" xsd:string property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001553 name: incisor tooth 6 crown height def: "The height of an incisor tooth 6 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001554 name: upper secondary incisor 6 tooth crown height def: "The height of an upper secondary incisor tooth 6 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "I6 crown height" EXACT [] is_a: FOVT:0001553 ! incisor tooth 6 crown height relationship: characteristic_of UBERON:0001709 ! upper jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001555 name: lower secondary incisor tooth 6 crown height def: "The height of a lower secondary incisor tooth 6 along the superior-inferior axis." [https://orcid.org/0000-0003-2699-3066] synonym: "i6 crown height" EXACT [] is_a: FOVT:0001553 ! incisor tooth 6 crown height is_a: OBA:VT0000458 ! mandible morphology trait relationship: characteristic_of UBERON:0001710 ! lower jaw region relationship: characteristic_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add incisor tooth 6" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001556 name: incisor tooth diameter def: "The diameter of an incisor tooth." [https://orcid.org/0000-0003-2699-3066] is_a: OBA:1000113 ! incisor size is_a: PATO:0001334 ! diameter intersection_of: PATO:0001334 ! diameter intersection_of: characteristic_of UBERON:0001098 ! incisor tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001557 name: metapodial bone of digit 2 proximal articular breadth def: "The breadth along the medial-lateral axis of the proximal end of a metapodial bone of digit 2." [] synonym: "metapodial II proximal articular breadth" EXACT [] synonym: "Metapodial II proximal breadth (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003646 ! metacarpal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add logical def" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001558 name: metacarpal bone of digit 3 medial length def: "The length of the medial side of a metacarpal bone of digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001559 name: metacarpal bone of digit 3 proximal articular depth def: "The depth of the proximal articular surface of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001560 name: metacarpal bone of digit 3 articular facet for the third carpal diameter def: "The diameter of the articular facet of the third carpal of a metacarpal of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal maximal diameter of the articular facet for the third carpal (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add facet" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001561 name: metacarpal bone of digit 3 anterior facet for the fourth carpal diameter def: "The diameter of the anterior facet for the fourth carpal of a metacarpal bone of digit 3 along the superior-inferior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal diameter of the anterior facet for the fourth carpal (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add facet" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001562 name: metacarpal bone of digit 3 articular facet for the second carpal diameter def: "The diameter of the articular facet for the second carpal of a metacarpal bone of digit 3 along the superior-inferior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal diameter of the articular facet for the second carpal (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add facet" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001563 name: metacarpal bone of digit 3 distal supra-articular breadth def: "The breadth of the distal supra-articular of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal maximal supra-articular breadth (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add supra-articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001564 name: metacarpal bone of digit 3 keel depth def: "The depth of the keel of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal maximal depth of the keel (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add keel" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001565 name: metacarpal bone of digit 3 medial condyle depth def: "The depth of the medial condyle of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal distal minimal depth of the medial condyle (M14)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add medial condyle" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001566 name: metacarpal bone of digit 3 posterior facet for the fourth carpal diameter def: "The diameter of the posterior facet for the fourth carpal of a metacarpal bone of digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third metacarpal diameter of the posterior facet for the fourth carpal (M16)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add facet" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001567 name: metacarpal bone of digit 2 diaphysis depth def: "The depth of the diaphysis of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002097 ! metacarpal bone diaphysis depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001568 name: metacarpal bone of digit 4 diaphysis depth def: "The depth of the diaphysis of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003648 ! metacarpal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001569 name: fused metacarpal bones 3 and 4 length def: "The length of a fused metacarpal bones 3 and 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "metacarpal III+IV greatest length (GL)" RELATED [ISBN:9780873659505] is_a: FOVT:0001140 ! fused metatarsal bones 3 and 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001570 name: fused metacarpal bones 3 and 4 diaphysis depth def: "The depth of the diaphysis of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III+IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001571 name: metacarpal bone of digit 2 proximal breadth def: "The breadth of the proximal side of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001572 name: metacarpal bone of digit 4 proximal breadth def: "The breadth of the proximal side of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metacarpal IV proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001573 name: fused metacarpal bones 3 and 4 proximal breadth def: "The breadth of the proximal side of a fused metacarpal bones 3 and 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal III+IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001574 name: metacarpal bone of digit 2 proximal depth def: "The length of the proximal end of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002099 ! metacarpal bone proximal depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001575 name: metacarpal bone of digit 4 proximal depth def: "The length of the proximal end of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002099 ! metacarpal bone proximal depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001576 name: fused metacarpal bones 3 and 4 proximal depth def: "The length of the proximal end of a fused metacarpal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III+IV greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001577 name: metacarpal bone of digit 2 distal articular breadth def: "The breadth of the distal articular surface of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003646 ! metacarpal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001578 name: metacarpal bone of digit 4 distal articular breadth def: "The breadth of the distal articular surface of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal IV distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003648 ! metacarpal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001579 name: metacapral bone of digit 2 distal articular depth def: "The depth of the distal articular of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003646 ! metacarpal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001580 name: metacapral bone of digit 4 distal articular depth def: "The depth of the distal articular of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal II distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003648 ! metacarpal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001581 name: obsolete metacarpal bone of digit 2 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metacarpal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: measurement not taken synonym: "metacarpal II greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001582 name: obsolete metacarpal bone of digit 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metacarpal bone of digit 4 along the proximal-distal axis." [ISBN:9780873659505] comment: measurement not taken synonym: "metacarpal IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001583 name: obsolete fused metacarpal bones 3 and 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a fused metacarpal bones 3 and 4 from the articular facet for the distal carpal bone 3 and anterior facet for the anterio facet for carpal bone 4 to the lateral condyle." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal III&IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 is_obsolete: true [Term] id: FOVT:0001584 name: fused metacarpal bones 3 and 4 outer lateral length def: "The length of the lateral side of a fused metacarpal bones 3 and 4 from the anterior facet for distal carpal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metacarpal III&IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001585 name: obsolete metacarpal bone of digit 2 outer lateral length def: "OBSOLETE. The length of the lateral side of a metacarpal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metacapral II lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001586 name: obsolete metacarpal bone of digit 4 outer lateral length def: "OBSOLETE. The length of the lateral side of a metacarpal bone of digit 4 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metacapral IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001587 name: obsolete metacarpal bone of digit 2 diaphysis breadth def: "OBSOLETE. The width of the diaphysis of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001588 name: metacarpal bone of digit 4 diaphysis breadth def: "The width of the diaphysis of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal IV breadth in the middle of the diaphysis (B)" RELATED [ISBN:9780873659505] is_a: FOVT:0002102 ! metacarpal bone diaphysis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001589 name: fused metacarpal bones 3 and 4 diaphysis breadth def: "The width of the diaphysis of a fused metacarpal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal III&IV smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001590 name: fused metacarpal bones 3 and 4 diaphysis circumference def: "The circumference of the diaphysis of a fused metacarpal boned 3 and 4." [ISBN:9780873659505] synonym: "metacarpal III&IV smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001648 ! circumference relationship: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001591 name: obsolete metacarpal bone of digit 2 diaphysis circumference def: "OBSOLETE. The circumference of the diaphysis of a metacarpal bone of digit 2." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001592 name: obsolete metacarpal bone of digit 4 diaphysis circumference def: "OBSOLETE. The circumference of the diaphysis of a metacarpal bone of digit 4." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal IV smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001593 name: obsolete metacarpal bone of digit 2 distal breadth def: "OBSOLETE. The width of the distal end of a metacarpal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001594 name: metacarpal bone of digit 4 distal breadth def: "The width of the distal end of a metacarpal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001595 name: fused metacarpal bones 3 and 4 distal breadth def: "The width of the distal end of a fused metacarpal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal III&IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001596 name: fused metacarpal bones 3 and 4 distal depth def: "The depth of the distal end of a fused metacarpal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III&IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001597 name: metacarpal bone of digit 2 distal depth def: "The depth of the distal end of a metacarpal bone of digit 2 along the anterior-posterior axis." [ISBN:9780873659505] comment: term not measured synonym: "metacarpal II greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003646 ! metacarpal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001598 name: metacarpal bone of digit 4 distal depth def: "The depth of the distal end of a metacarpal bone of digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001599 name: metacarpal bone of digit 3 outer lateral length def: "The length of the lateral side of a metacarpal bone of digit 3 from the anterior facet for distal carpal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metacarpal III lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001600 name: metacarpal bone of digit 3 diaphysis circumference def: "The circumference of the diaphysis of a metacarpal bone of digit 3." [ISBN:9780873659505] synonym: "metacarpal III smallest circumference of the diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:VT1000361 ! cannon bone circumference relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001601 name: metacarpal bone of digit 3 distal breadth def: "The width of the distal end of a metacarpal bone of digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal III greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001602 name: metacarpal bone of digit 3 distal depth def: "The depth of the distal end of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add distal" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001603 name: metatarsal bone of digit 3 medial length def: "The length on the medial size of a metatarsal bone of digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal medial length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001604 name: metatarsal bone of digit 3 diaphysis breadth def: "The breadth of the diaphysis of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third metatarsal minimal breadth (near the middle of the bone) (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002106 ! metatarsal bone diaphysis breadth is_a: OBA:1000413 ! metatarsal bone of digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001605 name: metatarsal bone of digit 3 diaphysis depth def: "The depth of the diaphysis of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III minimal depth of the diaphysis (DD)" RELATED [ISBN:9780873659505] synonym: "third metatarsal depth of the diaphysis at the level of M3 (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002105 ! metatarsal bone diaphysis depth is_a: OBA:1000413 ! metatarsal bone of digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001606 name: metatarsal bone of digit 3 proximal articular breadth def: "The breadth of the proximal articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third metatarsal proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001607 name: metatarsal bone of digit 3 proximal articular depth def: "The depth of the articular of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001608 name: metatarsal bone of digit 3 aricular facet for third tarsal diameter def: "The diameter of the articular facet for the third tarsal on a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal maximal diameter of the articular facet for the third tarsal (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001609 name: metatarsal bone of digit 3 aricular facet for fourth tarsal diameter def: "The diameter of the articular facet for fourth tarsal of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal diameter of the articular facet for the fourth tarsal (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001610 name: metatarsal bone of digit 3 aricular facet for second tarsal diameter synonym: "The diameter of the articular facet for second tarsal of a metatarsal bone of digit 3 along the anterior-posterior axis." RELATED [ISBN:9004086161\, 9789004086166] synonym: "third metarsal diameter of the articular facet for the second tarsal (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001334 ! diameter relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001611 name: metatarsal bone of digit 3 supra-articular breadth def: "The breadth of the supra-articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal maximal supra-articular breadth (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add supra-articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001612 name: metatarsal bone of digit 3 distal articular breadth def: "The breadth of the distal articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001613 name: metatarsal bone of digit 3 keel depth def: "The depth of the keel (on the distal end) of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal III greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] synonym: "third metatarsal distal maximal depth of the keel (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add keel" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001614 name: metatarsal bone of digit 3 lateral condyle depth def: "The depth of the lateral condyle of a metatarsal boen of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal minimal dpeth of the lateral condyle (M13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001615 name: metatarsal bone of digit 3 medial condyle depth def: "The depth of the medial condyle of a metatarsal bone of digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third metatarsal distal maximal depth of the medial condyle (M14)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001616 name: metatarsal bone of digit 2 diaphysis depth def: "The depth of the diaphysis of a metatarsal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002105 ! metatarsal bone diaphysis depth is_a: OBA:1000491 ! metatarsal bone of digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001617 name: metatarsal bone of digit 4 diaphysis depth def: "The depth of the diaphysis of a metatarsal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal IV minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002105 ! metatarsal bone diaphysis depth is_a: OBA:1000611 ! metatarsal bone of digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001618 name: fused metatarsal bones 3 and 4 diaphysis depth def: "The depth of the diaphysis of a fused metatarsal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metatarsal III&IV smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001619 name: metatarsal bone of digit 4 proximal depth def: "The depth of the proximal end of a metatarsal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal IV proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002108 ! metatarsal bone proximal depth is_a: OBA:1000611 ! metatarsal bone of digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001620 name: metatarsal bone of digit 2 proximal depth def: "The depth of the proximal end of a metatarsal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002108 ! metatarsal bone proximal depth is_a: OBA:1000491 ! metatarsal bone of digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001621 name: fused metatarsal bones 3 and 4 proximal depth def: "The depth of the proximal end of a fused metatarsal bones 3 and 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001622 name: metatarsal bone of digit 4 proximal breadth def: "The breadth of the proximal end of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metatarsal IV proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001623 name: metatarsal bone of digit 2 proximal breadth def: "The breadth of the proximal end of a metatarsal bone of digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:1000491 ! metatarsal bone of digit 2 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001624 name: fused metatarsal bones 3 and 4 proximal breadth def: "The breadth of the proximal end of a fused metatarsal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001625 name: metatarsal bone of digit 4 distal articular breadth def: "The breadth of the distal articular of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001626 name: metatarsal bone of digit 2 distal articular breadth def: "The breadth of the distal articular of a metatarsal bone of digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II distal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000491 ! metatarsal bone of digit 2 quality is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003651 ! metatarsal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001627 name: metatarsal bone of digit 4 distal articular depth def: "The depth of the distal articular of a metatarsal bone of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal IV distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001628 name: metatarsal bone of digit 2 distal articular depth def: "The depth of the distal articular of a metatarsal bone of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal II distal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000491 ! metatarsal bone of digit 2 quality is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003651 ! metatarsal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001629 name: obsolete metatarsal bone of digit 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metatarsal bone of digit 4 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001630 name: obsolete metatarsal bone of digit 4 outer lateral length def: "OBSOLETE. The length of the lateral side of a metatarsal bone of digit 4 from the lateral border of articular facet for distal carpal bone 4 to the lateral condyle." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001631 name: obsolete metatarsal bone of digit 2 lateral length def: "OBSOLETE. The greatest length of the lateral side of a metatarsal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001632 name: obsolete metatarsal bone of digit 2 outer lateral length def: "OBSOLETE. The length of the lateral side of a metatarsal bone of digit 2 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001633 name: obsolete fused metatarsal bones 3 and 4 lateral length def: "OBSOLETE. The greatest length of the lateral side of a fused metatarsal bones 3 and 4 along the proximal-distal axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal III&IV greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001634 name: fused metatarsal bones 3 and 4 outer lateral length def: "The length of the lateral side of a fused metatarsal bones 3 and 4 from the lateral border of articular facet for distal tarsal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metatarsal III&IV lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001635 name: fused metatarsal bones 3 and 4 diaphysis breadth def: "The breadth of the diaphysis of a fused metatarsal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal III&IV smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001636 name: metatarsal bone of digit 4 diaphysis breadth def: "The breadth of the diaphysis of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal IV breadth in the middle of the diaphysis (B)" RELATED [ISBN:9780873659505] is_a: FOVT:0002106 ! metatarsal bone diaphysis breadth is_a: OBA:1000611 ! metatarsal bone of digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001637 name: obsolete metatarsal bone of digit 2 diaphysis breadth def: "OBSOLETE. The breadth of the diaphysis of a metatarsal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001638 name: metatarsal bone of digit 4 diaphysis circumference def: "The circumference of the diaphysis of a metatarsal bone of digit 4." [ISBN:9780873659505] synonym: "metatarsal IV smallest circumference of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: PATO:0001648 ! circumference relationship: characteristic_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001639 name: obsolete metatarsal bone of digit 2 diaphysis circumference def: "OBSOLETE. The circumference of the diaphysis of a metatarsal bone of digit 2." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II smallest circumference of the diaphysis (SD)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001640 name: fused metatarsal bones 3 and 4 diaphysis circumference def: "The circumference of the diaphysis of a fused metatarsal bones 3 and 4." [ISBN:9780873659505] synonym: "metatarsal III&IV smallest circumference of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001648 ! circumference relationship: characteristic_of UBERON:0013587 ! fused metacarpal bones 3 and 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001641 name: metatarsal bone of digit 4 distal breadth def: "The breadth of the distal end of a metatarsal bone of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:1000611 ! metatarsal bone of digit 4 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001642 name: obsolete metatarsal bone of digit 2 distal breadth def: "OBSOLETE. The breadth of the distal end of a metatarsal bone of digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001643 name: fused metatarsals 3 and 4 distal depth def: "The depth of the distal end of a fused metatarsal bones 3 and 4 along the anterior-posteriod axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001644 name: obsolete metatarsal bone of digit 4 distal depth def: "OBSOLETE. The depth of the distal end of a metatarsal bone of digit 4 along the anterior-posteriod axis." [ISBN:9780873659505] comment: term not mreasured synonym: "metatarsal IV greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001645 name: obsolete metatarsal bone of digit 2 distal depth def: "OBSOLETE. The depth of the distal end of a metatarsal bone of digit 2 along the anterior-posteriod axis." [ISBN:9780873659505] comment: term not measured synonym: "metatarsal II greatest depth of the distal end (Dd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0001646 name: fused metatarsal bones 3 and 4 distal breadth def: "The breadth of the distal end of a fused metatarsal bones 3 and 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metatarsal III&IV greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9845 [Term] id: FOVT:0001648 name: metacarpal bone of digit 3 lateral length def: "The greatest length of the lateral side of a metacarpal bone 3 from the articular facet for the distal carpal bone 3 and anterior facet for the anterio facet for carpal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metacarpal III greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001649 name: metatarsal bone of digit 3 lateral length def: "The greatest length of the lateral side of a metatarsal bone of digit 3 from the articular facet for distal tarsal bone 3 and anterior facet for distal tarsal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metatarsal III greatest length of the lateral part (GLl)" RELATED [ISBN:9780873659505] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001650 name: metatarsal bone of digit 3 outer lateral length def: "The length of the lateral side of a metatarsal bone of digit 3 from the lateral border of articular facet for distal tarsal bone 4 to the lateral condyle." [ISBN:9780873659505] synonym: "metatarsal III lateral length on the outer side (Ll)" RELATED [ISBN:9780873659505] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:0001651 name: metacarpal bone of digit 5 distal breadth def: "The width of the distal end of a metacarpal bone of digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "metacarpal V greatest breadth of the distal end (Bp)" RELATED [ISBN:9780873659505] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:33554 property_value: measured_in_taxon NCBITaxon:9975 [Term] id: FOVT:0001652 name: metatarsal bone of digit 3 distal breadth def: "The width of the distal end of a metatarsal bone of digit 3 along the medial-lateral axis." [] synonym: "metatarsal III greatest breadth of the distal (Bp)" RELATED [] is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001653 name: metatarsal bone of digit 5 distal breadth def: "The width of the distal end of a metatarsal bone of digit 5 along the medial-lateral axis." [] synonym: "metatarsal V greatest breadth of the distal (Bp)" RELATED [] is_a: OBA:1000254 ! metatarsal bone of digit 5 quality is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:33554 property_value: measured_in_taxon NCBITaxon:9975 [Term] id: FOVT:0001654 name: metacarpal bone of digit 3 length excluding plantar projection def: "The length of a metacarpal bone of digit 3 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metacarpal III length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0003044 ! metacarpal bone of digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001655 name: metacarpal bone of digit 4 length excluding plantar projection def: "The length of a metacarpal bone of digit 4 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metacarpal IV length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0003045 ! metacarpal bone of digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001656 name: metatarsal bone of digit 3 length excluding plantar projection def: "The length of a metatarsal bone of digit 3 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metatarsal III length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0002565 ! metatarsal bone of digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001657 name: metatarsal bone of digit 4 length excluding plantar projection def: "The length of a metatarsal bone of digit 4 from the distal articular facets to the axial border of the proximal end." [ISBN:9780873659505] synonym: "metatarsal IV length excepting the plantar projection (LeP)" RELATED [ISBN:9780873659505] is_a: OBA:0002567 ! metatarsal bone of digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9822 [Term] id: FOVT:0001658 name: atlas breadth def: "The widht of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "atlas greatest breadth over wings (GB)" RELATED [ISBN:9780873659505] synonym: "C1 breadth" EXACT [] synonym: "vertebral bone 1 breadth" EXACT [] is_a: OBA:0004026 ! vertebral bone 1 morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001092 ! vertebral bone 1 relationship: characteristic_of UBERON:0001092 ! vertebral bone 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001659 name: atlas length def: "The length of an atlas along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "atlas greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "C1 length" EXACT [] synonym: "vertebral bone 1 length" EXACT [] is_a: OBA:0002823 ! vertebra size is_a: OBA:0004026 ! vertebral bone 1 morphology is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001092 ! vertebral bone 1 relationship: characteristic_of UBERON:0001092 ! vertebral bone 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001660 name: atlas cranial articular surface breadth def: "The width of the cranial articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "atlas greatest breadth of the Facies articularis cranialis (BFcr)" RELATED [ISBN:9780873659505] synonym: "C1 cranial articular surface breadth" EXACT [] synonym: "vertebral bone 1 cranial articular surface breadth" EXACT [] is_a: FOVT:0001658 ! atlas breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001661 name: atlas caudal articular surface breadth def: "The width of the caudal articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "atlas greatest breadth of the Facies articularis caudalis (BFcd)" RELATED [ISBN:9780873659505] synonym: "C1 caudal articular surface breadth" EXACT [] synonym: "vertebral bone 1 caudal articular surface breadth" EXACT [] is_a: FOVT:0001658 ! atlas breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001662 name: atlas length between cranial and caudal articular surface def: "The length from the cranial articular surface of an atlas to the caudal articular surface of an atlas." [ISBN:9780873659505] synonym: "atlas greatest length from the Facies articularis cranialis to the Facies articularis caudalis (GLF)" RELATED [ISBN:9780873659505] synonym: "C1 length between cranial and caudal articular surface" EXACT [] synonym: "vertebral bone 1 length between cranial and caudal articular surface" EXACT [] is_a: FOVT:0001659 ! atlas length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001663 name: atlas dorsal arch length def: "The length of the arch of atlas along the proximal-distal axis." [ISBN:9780873659505] synonym: "atlas length of the Arcus dorsalis (LAd)" RELATED [ISBN:9780873659505] synonym: "C1 dorsal arch length" EXACT [] synonym: "vertebral bone 1 dorsal arch length" EXACT [] is_a: OBA:0004026 ! vertebral bone 1 morphology is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0005814 ! arch of atlas relationship: characteristic_of UBERON:0005814 ! arch of atlas relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001664 name: atlas height def: "The height of an atlas along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "atlas height (H)" RELATED [ISBN:9780873659505] synonym: "C1 height" EXACT [] synonym: "vertebral bone 1 height" EXACT [] is_a: FOVT:0002132 ! vertebra height is_a: OBA:0004026 ! vertebral bone 1 morphology intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0001092 ! vertebral bone 1 relationship: characteristic_of UBERON:0001092 ! vertebral bone 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001665 name: axis body length def: "The length of the body of an axis along the proximal-distal axis." [ISBN:9780873659505] synonym: "axis greatest length in the region of the corpus including the dens (LCDe)" RELATED [ISBN:9780873659505] synonym: "C2 body length" EXACT [] synonym: "vertebral bone 2 body length" EXACT [] is_a: OBA:0004027 ! vertebral bone 2 morphology is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:2001984 ! centrum 2 relationship: characteristic_of UBERON:2001984 ! centrum 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001666 name: axis arch length def: "The length of the arch of an axis along the proximal-distal axis." [ISBN:9780873659505] synonym: "axis greatest length of the arch including the Processus articulares caudales (LAPa)" RELATED [ISBN:9780873659505] synonym: "C2 arch length" EXACT [] synonym: "vertebral bone 2 arch length" EXACT [] is_a: OBA:0004027 ! vertebral bone 2 morphology is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000218 ! vertebral arch of axis relationship: characteristic_of UBERON:0000218 ! vertebral arch of axis relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add arch" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001667 name: axis cranial articular surface breadth def: "The width of the cranial articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth of the Facis articularis cranialis (BFcr)" RELATED [ISBN:9780873659505] synonym: "C2 cranial articular surface breadth" EXACT [] synonym: "vertebral bone 2 cranial articular surface breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001668 name: axis caudal articular process breadth def: "The width of the caudal articular process of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth across the Processus articularis caudales (BPacd)" RELATED [ISBN:9780873659505] synonym: "C2 caudal articular process breadth" EXACT [] synonym: "vertebral bone 2 caudal articular process breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001669 name: axis transverse articular process breadth def: "The width of the transverse process of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth across the Processus transversi (BPtr)" RELATED [ISBN:9780873659505] synonym: "C2 transverse articular process breadth" EXACT [] synonym: "vertebral bone 2 transverse articular process breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add process" xsd:string property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001670 name: axis breadth def: "The width of an axis along the medial-lateral axis." [ISBN:9780873659505] synonym: "C2 breadth" EXACT [] synonym: "smallest breadth of the vertebra (SBV)" RELATED [ISBN:9780873659505] synonym: "vertebral bone 2 breadth" EXACT [] is_a: OBA:0004027 ! vertebral bone 2 morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001093 ! vertebral bone 2 relationship: characteristic_of UBERON:0001093 ! vertebral bone 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001671 name: axis caudal articular surface breadth def: "The width of the caudal articular surface of an atlas along the medial-lateral axis." [ISBN:9780873659505] synonym: "axis greatest breadth of the Facis terminalis caudalis (BFcd)" RELATED [ISBN:9780873659505] synonym: "C2 caudal articular surface breadth" EXACT [] synonym: "vertebral bone 2 caudal articular surface breadth" EXACT [] is_a: FOVT:0001670 ! axis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: editor_note "need to add process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001672 name: axis height def: "The height of an axis along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "axis greatest height (H)" RELATED [ISBN:9780873659505] synonym: "C2 height" EXACT [] synonym: "vertebral bone 2 height" EXACT [] is_a: FOVT:0002132 ! vertebra height is_a: OBA:0004027 ! vertebral bone 2 morphology intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0001093 ! vertebral bone 2 relationship: characteristic_of UBERON:0001093 ! vertebral bone 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001673 name: proximal phalanx of manual digit 3 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001674 name: proximal phalanx of manual digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001675 name: obsolete proximal phalanx of manual digit 3 proximal breadth comment: already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001673 [Term] id: FOVT:0001676 name: proximal phalanx of manual digit 3 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001677 name: proximal phalanx of manual digit 3 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001678 name: proximal phalanx of manual digit 3 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001679 name: obsolete proximal phalanx of manual digit 3 distal breadth comment: already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0001676 [Term] id: FOVT:0001680 name: proximal phalanx of manual digit 3 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001681 name: proximal phalanx of manual digit 3 distal articular surface depth def: "The depth of the distal articular surface of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit distal articular depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001682 name: proximal phalanx of manual digit 3 trigonum phalangis length def: "The length of the trigonum phalangis of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit minimal length of the trigonum phalangis (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonum phalangis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001683 name: proximal phalanx of manual digit 3 medial supratuberosity length def: "The length of the medial surpatuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial supratuberosital length (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add supraturberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001684 name: proximal phalanx of manual digit 3 lateral supratuberosity length def: "The length of the lateral surpatuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral supratuberosital length (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add supraturberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001685 name: proximal phalanx of manual digit 3 lateral infratuberosity length def: "The length of the lateral infratuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral infratuberosital length (M13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add infraturberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001686 name: proximal phalanx of manual digit 3 medial infratuberosity length def: "The length of the medial infratuberosity of a proximal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial infratuberosital length (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002956 ! proximal phalanx of manual digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add infraturberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001687 name: proximal phalanx of manual digit 3 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001688 name: proximal phalanx of pedal digit 3 length def: "The length of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003281 ! proximal phalanx of pes length is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004334 ! proximal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001689 name: proximal phalanx of pedal digit 3 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001690 name: proximal phalanx of pedal digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001691 name: proximal phalanx of pedal digit 3 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001692 name: proximal phalanx of pedal digit 3 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001693 name: proximal phalanx of pedal digit 3 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001694 name: proximal phalanx of pedal digit 3 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001695 name: proximal phalanx of pedal digit 3 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001696 name: proximal phalanx of pedal digit 3 distal articular surface depth def: "The depth of the distal articular surface of a proximal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit distal articular depth (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003372 ! proximal phalanx of pedal digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001697 name: proximal phalanx of pedal digit 3 trigonum phalangis length def: "The length of a trigonum phalangis of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit minimal length of the trigonum phalangis (M9)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add trigonum phalangis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001698 name: proximal phalanx of pedal digit 3 medial supratuberosity length def: "The length of a medial supratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial supratuberosital length (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular supratuberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001699 name: proximal phalanx of pedal digit 3 lateral supratuberosity length def: "The length of a lateral supratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral supratuberosital length (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular supratuberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001700 name: proximal phalanx of pedal digit 3 medial infratuberosity length def: "The length of a medial infratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit medial infratuberosital length (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular infratuberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001701 name: proximal phalanx of pedal digit 3 lateral infratuberosity length def: "The length of a lateral infratuberosity of a proximal phalanx of pedal digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit lateral infratuberosital length (M13)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0001688 ! proximal phalanx of pedal digit 3 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular infratuberosity" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001702 name: middle phalanx of manual digit 3 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001703 name: middle phalanx of manual digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002943 ! middle phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001705 name: middle phalanx of manual digit 3 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001706 name: middle phalanx of manual digit 3 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001707 name: middle phalanx of manual digit 3 anterior length def: "The length of the anterior side of a middle phalanx of manual digit 3 along the middle-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002128 ! phalanx of manus anterior length is_a: OBA:1000382 ! middle phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001714 name: middle phalanx of manual digit 3 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001715 name: middle phalanx of pedal digit 3 length def: "The length of a middle phalanx of pedal digit 3 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003369 ! middle phalanx of pedal digit 3 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004325 ! middle phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001716 name: middle phalanx of pedal digit 3 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001717 name: middle phalanx of pedal digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003369 ! middle phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001718 name: middle phalanx of pedal digit 3 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001719 name: middle phalanx of pedal digit 3 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001720 name: middle phalanx of pedal digit 3 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001722 name: middle phalanx of pedal digit 3 anterior length def: "The length of the anterior side of a middle phalanx of pedal digit 3 along the middle-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002125 ! phalanx of pes anterior length is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001723 name: distal phalanx of manual digit 3 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001724 name: distal phalanx of manual digit 3 articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of facies articularis (BF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit articular breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9788 [Term] id: FOVT:0001725 name: distal phalanx of manual digit 3 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001726 name: distal phalanx of manual digit 3 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001727 name: distal phalanx of manual digit 3 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 3 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001728 name: distal phalanx of manual digit 3 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001729 name: distal phalanx of pedal digit 3 length def: "The length of a distal phalanx of pedal digit 3 along the distal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001730 name: distal phalanx of pedal digit 3 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001731 name: distal phalanx of pedal digit 3 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001732 name: distal phalanx of pedal digit 3 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit proximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001733 name: distal phalanx of pedal digit 3 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001734 name: distal phalanx of pedal digit 3 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of central digit distal breadth at the tuberosities (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001735 name: distal phalanx of pedal digit 3 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 3 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of central digit anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001736 name: middle phalanx of manual digit 5 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001737 name: middle phalanx of manual digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002895 ! middle phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001738 name: middle phalanx of manual digit 5 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001739 name: middle phalanx of manual digit 5 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001741 name: middle phalanx of manual digit 5 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001742 name: middle phalanx of pedal digit 5 length def: "The length of a middle phalanx of pedal digit 5 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003371 ! middle phalanx of pedal digit 5 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004327 ! middle phalanx of pedal digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001743 name: middle phalanx of pedal digit 5 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001744 name: middle phalanx of pedal digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003371 ! middle phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001745 name: middle phalanx of pedal digit 5 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001746 name: middle phalanx of pedal digit 5 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001747 name: middle phalanx of pedal digit 5 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001748 name: distal phalanx of manual digit 1 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001749 name: distal phalanx of manual digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002990 ! distal phalanx of manual digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001750 name: distal phalanx of manual digit 1 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001751 name: distal phalanx of manual digit 1 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001752 name: distal phalanx of manual digit 1 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 1 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of first digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001753 name: distal phalanx of manual digit 1 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001754 name: distal phalanx of pedal digit 1 length def: "The length of a distal phalanx of pedal digit 1 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003057 ! distal phalanx of pedal digit 1 size is_a: OBA:0003067 ! pedal digit 1 phalanx length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004315 ! distal phalanx of pedal digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001755 name: distal phalanx of pedal digit 1 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001756 name: distal phalanx of pedal digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003057 ! distal phalanx of pedal digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001757 name: distal phalanx of pedal digit 1 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 1 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001758 name: distal phalanx of pedal digit 1 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001759 name: distal phalanx of pedal digit 1 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001760 name: distal phalanx of pedal digit 1 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 1 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of first digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001761 name: middle phalanx of manual digit 2 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001762 name: middle phalanx of manual digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002971 ! middle phalanx of manual digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001763 name: middle phalanx of manual digit 2 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001764 name: middle phalanx of manual digit 2 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001766 name: middle phalanx of manual digit 2 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001767 name: middle phalanx of pedal digit 2 length def: "The length of a middle phalanx of pedal digit 2 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003131 ! middle phalanx of pedal digit 2 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004324 ! middle phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001768 name: middle phalanx of pedal digit 2 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001769 name: middle phalanx of pedal digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003131 ! middle phalanx of pedal digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001770 name: middle phalanx of pedal digit 2 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001771 name: middle phalanx of pedal digit 2 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001772 name: middle phalanx of pedal digit 2 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001774 name: middle phalanx of manual digit 4 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001775 name: middle phalanx of manual digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002920 ! middle phalanx of manual digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001776 name: middle phalanx of manual digit 4 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001777 name: middle phalanx of manual digit 4 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001780 name: middle phalanx of manual digit 4 proximal depth def: "The depth of the middle end of a middle phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001781 name: middle phalanx of pedal digit 4 length def: "The length of a middle phalanx of pedal digit 4 along the middle-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002452 ! middle phalanx of pes length is_a: OBA:0003370 ! middle phalanx of pedal digit 4 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004326 ! middle phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001782 name: middle phalanx of pedal digit 4 proximal breadth def: "The width of the middle end of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001783 name: middle phalanx of pedal digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003370 ! middle phalanx of pedal digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001784 name: middle phalanx of pedal digit 4 proximal depth def: "The depth of the middle end of a middle phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002127 ! phalanx of pes proximal depth is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001785 name: middle phalanx of pedal digit 4 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001786 name: middle phalanx of pedal digit 4 distal breadth def: "The width of the distal end of a middle phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002084 ! middle phalanx of pes distal breadth is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001788 name: distal phalanx of manual digit 5 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001789 name: distal phalanx of manual digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002909 ! distal phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001790 name: distal phalanx of manual digit 5 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001791 name: distal phalanx of manual digit 5 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001792 name: distal phalanx of manual digit 5 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 5 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fifth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001793 name: distal phalanx of manual digit 5 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001794 name: distal phalanx of pedal digit 5 length def: "The length of a distal phalanx of pedal digit 5 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003368 ! distal phalanx of pedal digit 5 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004319 ! distal phalanx of pedal digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001795 name: distal phalanx of pedal digit 5 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001796 name: distal phalanx of pedal digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003368 ! distal phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001797 name: distal phalanx of pedal digit 5 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 5 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001798 name: distal phalanx of pedal digit 5 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001799 name: distal phalanx of pedal digit 5 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001800 name: distal phalanx of pedal digit 5 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 5 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fifth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001801 name: distal phalanx of manual digit 4 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001802 name: distal phalanx of manual digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002166 ! distal phalanx of manual digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001803 name: distal phalanx of manual digit 4 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001804 name: distal phalanx of manual digit 4 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001805 name: distal phalanx of manual digit 4 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 4 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fourth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001806 name: distal phalanx of manual digit 4 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001807 name: distal phalanx of pedal digit 4 length def: "The length of a distal phalanx of pedal digit 4 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003367 ! distal phalanx of pedal digit 4 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001808 name: distal phalanx of pedal digit 4 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001809 name: distal phalanx of pedal digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002165 ! distal phalanx of pedal digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001810 name: distal phalanx of pedal digit 4 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001811 name: distal phalanx of pedal digit 4 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001812 name: distal phalanx of pedal digit 4 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001813 name: distal phalanx of pedal digit 4 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 4 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of fourth digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001814 name: distal phalanx of manual digit 2 proximal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002079 ! distal phalanx of manus proximal breadth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001815 name: distal phalanx of manual digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002153 ! distal phalanx of manual digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001816 name: distal phalanx of manual digit 2 distal breadth def: "The breadth of the distal end of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002077 ! distal phalanx of manus distal breadth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001817 name: distal phalanx of manual digit 2 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002076 ! distal phalanx of manus diaphysis breadth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001818 name: distal phalanx of manual digit 2 anterior length def: "The length of the anterior side of a distal phalanx of manual digit 2 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of second digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002075 ! distal phalanx of manus anterior length is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001819 name: distal phalanx of manual digit 2 proximal depth def: "The depth of the distal end of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002080 ! distal phalanx of manus proximal depth is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001820 name: distal phalanx of pedal digit 2 length def: "The length of a distal phalanx of pedal digit 2 along the distal-distal axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002267 ! distal phalanx of pes length is_a: OBA:0003135 ! distal phalanx of pedal digit 2 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001821 name: distal phalanx of pedal digit 2 proximal breadth def: "The width of the distal end of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002073 ! distal phalanx of pes proximal breadth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001822 name: distal phalanx of pedal digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002154 ! distal phalanx of pedal digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001823 name: distal phalanx of pedal digit 2 proximal depth def: "The depth of the distal end of a distal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002074 ! distal phalanx of pes proximal depth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001824 name: distal phalanx of pedal digit 2 diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: FOVT:0002070 ! distal phalanx of pes diaphysis breadth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001825 name: distal phalanx of pedal digit 2 distal breadth def: "The width of the distal end of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002071 ! distal phalanx of pes distal breadth is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001826 name: distal phalanx of pedal digit 2 anterior length def: "The length of the anterior side of a distal phalanx of pedal digit 2 along the distal-distal axis." [ISBN:9004086161\, 9789004086166] synonym: "first phalanx of second digit anterior length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002069 ! distal phalanx of pes anterior length is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001827 name: middle phalanx of manual digit 1 proximal breadth def: "The breadth of the middle end of a middle phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 2 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000382 ! middle phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001828 name: middle phalanx of manual digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a middle phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 2 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003009 ! middle phalanx of manus size is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:4200219 ! middle phalanx of manual digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001829 name: middle phalanx of manual digit 1 distal breadth def: "The breadth of the distal end of a middle phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 2 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002083 ! middle phalanx of manus distal breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001830 name: middle phalanx of manual digit 1 diaphysis breadth def: "The width of the diaphysis of a middle phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 2 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000382 ! middle phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001831 name: proximal phalanx of manual digit 1 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001832 name: proximal phalanx of manual digit 1 proximal articular surface breadth def: "The depth of the middle end of a middle phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] def: "The width of the proximal articular surface of a proximal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] synonym: "digit 1 phalanx 2 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002986 ! proximal phalanx of manual digit 1 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001833 name: proximal phalanx of manual digit 1 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001834 name: proximal phalanx of manual digit 1 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002986 ! proximal phalanx of manual digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001835 name: proximal phalanx of manual digit 1 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000610 ! proximal phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001836 name: proximal phalanx of manual digit 1 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 1 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001837 name: proximal phalanx of manual digit 1 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001838 name: proximal phalanx of pedal digit 1 length def: "The length of a proximal phalanx of pedal digit 1 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003061 ! proximal phalanx of pedal digit 1 size is_a: OBA:0003067 ! pedal digit 1 phalanx length is_a: OBA:0003281 ! proximal phalanx of pes length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004332 ! proximal phalanx of pedal digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001839 name: proximal phalanx of pedal digit 1 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001840 name: proximal phalanx of pedal digit 1 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003061 ! proximal phalanx of pedal digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001841 name: proximal phalanx of pedal digit 1 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 1 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001842 name: proximal phalanx of pedal digit 1 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001843 name: proximal phalanx of pedal digit 1 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of first digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001844 name: proximal phalanx of pedal digit 1 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003061 ! proximal phalanx of pedal digit 1 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001845 name: proximal phalanx of pedal digit 1 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 1 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 1 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001847 name: proximal phalanx of manual digit 2 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001848 name: proximal phalanx of manual digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002976 ! proximal phalanx of manual digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001849 name: proximal phalanx of manual digit 2 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001850 name: proximal phalanx of manual digit 2 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002976 ! proximal phalanx of manual digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001851 name: proximal phalanx of manual digit 2 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001853 name: proximal phalanx of manual digit 2 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001854 name: proximal phalanx of manual digit 2 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001855 name: proximal phalanx of pedal digit 2 length def: "The length of a proximal phalanx of pedal digit 2 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003127 ! proximal phalanx of pedal digit 2 size is_a: OBA:0003281 ! proximal phalanx of pes length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004333 ! proximal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001856 name: proximal phalanx of pedal digit 2 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001857 name: proximal phalanx of pedal digit 2 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003127 ! proximal phalanx of pedal digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001858 name: proximal phalanx of pedal digit 2 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001859 name: proximal phalanx of pedal digit 2 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001860 name: proximal phalanx of pedal digit 2 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of second digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001861 name: proximal phalanx of pedal digit 2 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003127 ! proximal phalanx of pedal digit 2 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001862 name: proximal phalanx of pedal digit 2 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 2 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001863 name: proximal phalanx of manual digit 5 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001864 name: proximal phalanx of manual digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002904 ! proximal phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001865 name: proximal phalanx of manual digit 5 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001866 name: proximal phalanx of manual digit 5 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002904 ! proximal phalanx of manual digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001867 name: proximal phalanx of manual digit 5 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001868 name: proximal phalanx of manual digit 5 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 5 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001869 name: proximal phalanx of manual digit 5 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001870 name: proximal phalanx of pedal digit 5 length def: "The length of a proximal phalanx of pedal digit 5 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003281 ! proximal phalanx of pes length is_a: OBA:0003374 ! proximal phalanx of pedal digit 5 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004336 ! proximal phalanx of pedal digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001871 name: proximal phalanx of pedal digit 5 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001872 name: proximal phalanx of pedal digit 5 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003374 ! proximal phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001873 name: proximal phalanx of pedal digit 5 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 5 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001874 name: proximal phalanx of pedal digit 5 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001875 name: proximal phalanx of pedal digit 5 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fifth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001876 name: proximal phalanx of pedal digit 5 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003374 ! proximal phalanx of pedal digit 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001877 name: proximal phalanx of pedal digit 5 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 5 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 5 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001878 name: proximal phalanx of manual digit 4 proximal breadth def: "The breadth of the proximal end of a proximal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001879 name: proximal phalanx of manual digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0002927 ! proximal phalanx of manual digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001880 name: proximal phalanx of manual digit 4 distal breadth def: "The breadth of the distal end of a proximal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002086 ! proximal phalanx of manus distal breadth is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001881 name: proximal phalanx of manual digit 4 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0002927 ! proximal phalanx of manual digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001882 name: proximal phalanx of manual digit 4 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001883 name: proximal phalanx of manual digit 4 anterior length def: "The length of the anterior side of a proximal phalanx of manual digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002137 ! proximal phalanx of manus anterior length is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001884 name: proximal phalanx of manual digit 4 proximal depth def: "The depth of the proximal end of a proximal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001885 name: proximal phalanx of pedal digit 4 length def: "The length of a proximal phalanx of pedal digit 4 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003281 ! proximal phalanx of pes length is_a: OBA:0003373 ! proximal phalanx of pedal digit 4 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004335 ! proximal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001886 name: proximal phalanx of pedal digit 4 proximal breadth def: "The width of the proximal end of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal breadth (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001887 name: proximal phalanx of pedal digit 4 proximal articular surface breadth def: "The width of the proximal articular surface of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003373 ! proximal phalanx of pedal digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001888 name: proximal phalanx of pedal digit 4 proximal depth def: "The depth of the proximal end of a proximal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit proximal depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001889 name: proximal phalanx of pedal digit 4 diaphysis breadth def: "The width of the diaphysis of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit minimal breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001890 name: proximal phalanx of pedal digit 4 distal breadth def: "The width of the distal end of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "first phalanx of fourth digit distal breadth at the tuberosities (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002088 ! proximal phalanx of pes distal breadth is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001891 name: proximal phalanx of pedal digit 4 distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003373 ! proximal phalanx of pedal digit 4 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001892 name: proximal phalanx of pedal digit 4 anterior length def: "The length of the anterior side of a proximal phalanx of pedal digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "digit 4 phalanx 1 greatest length of the peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002138 ! proximal phalanx of pes anterior length is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001893 name: sacrum length def: "The length on the ventral side of a fused sacrum along the proximal-distal axis." [ISBN:9780873659505] comment: This is measured from the cranial borders of the wings to the centroventral border of the body of the last vertebra. {xref="ISBN:9780873659505"} synonym: "fused sacrum length" EXACT [] synonym: "sacrum greatest length of the ventral side (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0002556 ! fused sacrum size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003690 ! fused sacrum relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001894 name: sacrum physiological length def: "The length of the body of a fused sacrum on the ventral side along the proximal-distal axis." [ISBN:9780873659505] comment: This is measured between the centers of the bodies of the most cranial and most caudal vertebrae. {xref="ISBN:9780873659505"} synonym: "fused sacrum physiological length" EXACT [] synonym: "sacrum physiological length (PL)" RELATED [ISBN:9780873659505] is_a: FOVT:0001893 ! sacrum length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001895 name: sacrum breadth def: "The width of a fused sacrum along the medial-lateral axis." [ISBN:9780873659505] synonym: "fused sacrum breadth" EXACT [] synonym: "sacrum greatest breadth across the wings (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0002556 ! fused sacrum size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0003690 ! fused sacrum relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001896 name: sacrum cranial articular surface breadth def: "The width of the cranial articular surface of a fused sacrum along the medial-lateral axis." [ISBN:9780873659505] synonym: "fused sacrum cranial articular surface breadth" EXACT [] synonym: "sacrum greatest breadth of the facies terminalis cranialis (BFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001895 ! sacrum breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001897 name: sacrum cranial articular surface height def: "The height of the cranial articular surface of a fused sacrum along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "fused sacrum cranial articular surface height" EXACT [] synonym: "sacrum greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: OBA:0002556 ! fused sacrum size is_a: PATO:0000119 ! height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001898 name: thoracic vertebra physiological length def: "The length of the body of a thoracic vertebra along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0002347 ! thoracic vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001899 name: thoracic vertebra transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0002347 ! thoracic vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001900 name: thoracic vertebra cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0002347 ! thoracic vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001901 name: thoracic vertebra caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0002347 ! thoracic vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001902 name: thoracic vertebra cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001903 name: thoracic vertebra caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001904 name: thoracic vertebra height def: "The height of a thoracic vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height is_a: OBA:VT0003047 ! thoracic vertebra morphology trait intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0002347 ! thoracic vertebra relationship: characteristic_of UBERON:0002347 ! thoracic vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001905 name: cervical vertebra physiological length def: "The length of the body of a cervical vertebra along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "cervical vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001906 name: cervical vertebra length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001907 name: cervical vertebra cranial articular process breadth def: "The width of the cranial articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001908 name: cervical vertebra caudal articular process breadth def: "The width of the caudal articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001909 name: cervical vertebra transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002134 ! vertebra transverse process breadth intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018143 ! transverse process of cervical vertebra relationship: characteristic_of UBERON:0018143 ! transverse process of cervical vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001910 name: cervical vertebra cranial articular surface height def: "The hieght of the cranial articular surface of a cervical vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001911 name: cervical vertebra caudal articular surface height def: "The hieght of the caudal articular surface of a cervical vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001912 name: cervical vertebra height def: "The height of a cervical vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "cervical vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height is_a: OBA:0002830 ! cervical vertebra size intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0002413 ! cervical vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001913 name: lumbar vertebra physiological length def: "The length of the body of a lumbar vertebra along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001914 name: lumbar vertebra transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002134 ! vertebra transverse process breadth is_a: OBA:VT0010494 ! lumbar vertebra morphology trait intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0018146 ! transverse process of lumbar vertebra relationship: characteristic_of UBERON:0018146 ! transverse process of lumbar vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001915 name: lumbar vertebra cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001916 name: lumbar vertebra caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001917 name: lumbar vertebra height def: "The height of a lumbar vertebra along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height is_a: OBA:VT0010518 ! lumbar vertebra size trait intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0002414 ! lumbar vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001918 name: thoracic vertebra 1 physiological length def: "The length of the body of a thoracic vertebra 1 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 1 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004626 ! thoracic vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001919 name: thoracic vertebra 1 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004626 ! thoracic vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001920 name: thoracic vertebra 1 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004626 ! thoracic vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001921 name: thoracic vertebra 1 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004626 ! thoracic vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001922 name: thoracic vertebra 1 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001924 ! thoracic vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001923 name: thoracic vertebra 1 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001924 ! thoracic vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001924 name: thoracic vertebra 1 height def: "The height of a thoracic vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 1 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004626 ! thoracic vertebra 1 relationship: characteristic_of UBERON:0004626 ! thoracic vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001925 name: thoracic vertebra 2 physiological length def: "The length of the body of a thoracic vertebra 2 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 2 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004627 ! thoracic vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001926 name: thoracic vertebra 2 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004627 ! thoracic vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001927 name: thoracic vertebra 2 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004627 ! thoracic vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001928 name: thoracic vertebra 2 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004627 ! thoracic vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001929 name: thoracic vertebra 2 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001931 ! thoracic vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001930 name: thoracic vertebra 2 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001931 ! thoracic vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001931 name: thoracic vertebra 2 height def: "The height of a thoracic vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 2 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004627 ! thoracic vertebra 2 relationship: characteristic_of UBERON:0004627 ! thoracic vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001932 name: thoracic vertebra 3 physiological length def: "The length of the body of a thoracic vertebra 3 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 3 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004628 ! thoracic vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001933 name: thoracic vertebra 3 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004628 ! thoracic vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001934 name: thoracic vertebra 3 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004628 ! thoracic vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001935 name: thoracic vertebra 3 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004628 ! thoracic vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001936 name: thoracic vertebra 3 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001938 ! thoracic vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001937 name: thoracic vertebra 3 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001938 ! thoracic vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001938 name: thoracic vertebra 3 height def: "The height of a thoracic vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 3 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004628 ! thoracic vertebra 3 relationship: characteristic_of UBERON:0004628 ! thoracic vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001939 name: thoracic vertebra 5 physiological length def: "The length of the body of a thoracic vertebra 5 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 5 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004630 ! thoracic vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001940 name: thoracic vertebra 5 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004630 ! thoracic vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001941 name: thoracic vertebra 5 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004630 ! thoracic vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001942 name: thoracic vertebra 5 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004630 ! thoracic vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001943 name: thoracic vertebra 5 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001945 ! thoracic vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001944 name: thoracic vertebra 5 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001945 ! thoracic vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001945 name: thoracic vertebra 5 height def: "The height of a thoracic vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 5 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004630 ! thoracic vertebra 5 relationship: characteristic_of UBERON:0004630 ! thoracic vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001946 name: thoracic vertebra 4 physiological length def: "The length of the body of a thoracic vertebra 4 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 4 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004629 ! thoracic vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001947 name: thoracic vertebra 4 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004629 ! thoracic vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001948 name: thoracic vertebra 4 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004629 ! thoracic vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001949 name: thoracic vertebra 4 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004629 ! thoracic vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001950 name: thoracic vertebra 4 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001952 ! thoracic vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001951 name: thoracic vertebra 4 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001952 ! thoracic vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001952 name: thoracic vertebra 4 height def: "The height of a thoracic vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 4 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004629 ! thoracic vertebra 4 relationship: characteristic_of UBERON:0004629 ! thoracic vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001953 name: thoracic vertebra 6 physiological length def: "The length of the body of a thoracic vertebra 6 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 6 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004631 ! thoracic vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001954 name: thoracic vertebra 6 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004631 ! thoracic vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001955 name: thoracic vertebra 6 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004631 ! thoracic vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001956 name: thoracic vertebra 6 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004631 ! thoracic vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001957 name: thoracic vertebra 6 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001959 ! thoracic vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001958 name: thoracic vertebra 6 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001959 ! thoracic vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001959 name: thoracic vertebra 6 height def: "The height of a thoracic vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 6 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004631 ! thoracic vertebra 6 relationship: characteristic_of UBERON:0004631 ! thoracic vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001960 name: thoracic vertebra 12 physiological length def: "The length of the body of a thoracic vertebra 12 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 12 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004636 ! thoracic vertebra 12 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0001961 name: thoracic vertebra 12 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004636 ! thoracic vertebra 12 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001962 name: thoracic vertebra 12 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 12 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004636 ! thoracic vertebra 12 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001963 name: thoracic vertebra 12 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 12 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004636 ! thoracic vertebra 12 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001964 name: thoracic vertebra 12 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 12 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001966 ! thoracic vertebra 12 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001965 name: thoracic vertebra 12 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 12 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001966 ! thoracic vertebra 12 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001966 name: thoracic vertebra 12 height def: "The height of a thoracic vertebra 12 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 12 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004636 ! thoracic vertebra 12 relationship: characteristic_of UBERON:0004636 ! thoracic vertebra 12 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001967 name: thoracic vertebra 7 physiological length def: "The length of the body of a thoracic vertebra 7 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 7 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004632 ! thoracic vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001968 name: thoracic vertebra 7 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004632 ! thoracic vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001969 name: thoracic vertebra 7 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004632 ! thoracic vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001970 name: thoracic vertebra 7 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004632 ! thoracic vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001971 name: thoracic vertebra 7 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001973 ! thoracic vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001972 name: thoracic vertebra 7 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001973 ! thoracic vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001973 name: thoracic vertebra 7 height def: "The height of a thoracic vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 7 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004632 ! thoracic vertebra 7 relationship: characteristic_of UBERON:0004632 ! thoracic vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001974 name: thoracic vertebra 11 physiological length def: "The length of the body of a thoracic vertebra 11 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 11 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004635 ! thoracic vertebra 11 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001975 name: thoracic vertebra 11 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004635 ! thoracic vertebra 11 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001976 name: thoracic vertebra 11 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 11 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004635 ! thoracic vertebra 11 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001977 name: thoracic vertebra 11 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 11 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004635 ! thoracic vertebra 11 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001978 name: thoracic vertebra 11 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 11 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001980 ! thoracic vertebra 11 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001979 name: thoracic vertebra 11 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 11 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001980 ! thoracic vertebra 11 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001980 name: thoracic vertebra 11 height def: "The height of a thoracic vertebra 11 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 11 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004635 ! thoracic vertebra 11 relationship: characteristic_of UBERON:0004635 ! thoracic vertebra 11 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001981 name: thoracic vertebra 8 physiological length def: "The length of the body of a thoracic vertebra 8 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 8 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0011050 ! thoracic vertebra 8 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001982 name: thoracic vertebra 8 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0011050 ! thoracic vertebra 8 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001983 name: thoracic vertebra 8 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 8 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0011050 ! thoracic vertebra 8 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001984 name: thoracic vertebra 8 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 8 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0011050 ! thoracic vertebra 8 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001985 name: thoracic vertebra 8 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 8 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001987 ! thoracic vertebra 8 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001986 name: thoracic vertebra 8 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 8 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001987 ! thoracic vertebra 8 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001987 name: thoracic vertebra 8 height def: "The height of a thoracic vertebra 8 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 8 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0011050 ! thoracic vertebra 8 relationship: characteristic_of UBERON:0011050 ! thoracic vertebra 8 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001988 name: thoracic vertebra 9 physiological length def: "The length of the body of a thoracic vertebra 9 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 9 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004633 ! thoracic vertebra 9 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001989 name: thoracic vertebra 9 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004633 ! thoracic vertebra 9 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001990 name: thoracic vertebra 9 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 9 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004633 ! thoracic vertebra 9 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001991 name: thoracic vertebra 9 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 9 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004633 ! thoracic vertebra 9 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001992 name: thoracic vertebra 9 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 9 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0001994 ! thoracic vertebra 9 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001993 name: thoracic vertebra 9 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 9 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0001994 ! thoracic vertebra 9 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001994 name: thoracic vertebra 9 height def: "The height of a thoracic vertebra 9 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 9 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004633 ! thoracic vertebra 9 relationship: characteristic_of UBERON:0004633 ! thoracic vertebra 9 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001995 name: thoracic vertebra 10 physiological length def: "The length of the body of a thoracic vertebra 10 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "thoracic vertebra 10 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004634 ! thoracic vertebra 10 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001996 name: thoracic vertebra 10 transverse process breadth def: "The width between a left and right transverse process along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004634 ! thoracic vertebra 10 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001997 name: thoracic vertebra 10 cranial articular surface breadth def: "The width of the cranial articular surface of a thoracic vertebra 10 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest breadth of the processus articulares craniales breadth (BFcr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004634 ! thoracic vertebra 10 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001998 name: thoracic vertebra 10 caudal articular surface breadth def: "The width of the caudal articular surface of a thoracic vertebra 10 along the medial-lateral axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest breadth of the processus articulares caudales breadth (BFcd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0003047 ! thoracic vertebra morphology trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004634 ! thoracic vertebra 10 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0001999 name: thoracic vertebra 10 cranial articular surface height def: "The height of the cranial articular surface of a thoracic vertebra 10 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest height of the processus articulares craniales height (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002001 ! thoracic vertebra 10 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002000 name: thoracic vertebra 10 caudal articular surface height def: "The height of the caudal articular surface of a thoracic vertebra 10 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest height of the processus articulares caudales height (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002001 ! thoracic vertebra 10 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002001 name: thoracic vertebra 10 height def: "The height of a thoracic vertebra 10 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "thoracic vertebra 10 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001904 ! thoracic vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004634 ! thoracic vertebra 10 relationship: characteristic_of UBERON:0004634 ! thoracic vertebra 10 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002002 name: lumbar vertebra 1 physiological length def: "The length of the body of a lumbar vertebra 1 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 1 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002003 name: lumbar vertebra 1 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 1 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004617 ! lumbar vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002004 name: lumbar vertebra 1 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 1 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002006 ! lumbar vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002005 name: lumbar vertebra 1 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 1 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002006 ! lumbar vertebra 1 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002006 name: lumbar vertebra 1 height def: "The height of a lumbar vertebra 1 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 1 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004617 ! lumbar vertebra 1 relationship: characteristic_of UBERON:0004617 ! lumbar vertebra 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002007 name: lumbar vertebra 3 physiological length def: "The length of the body of a lumbar vertebra 3 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 3 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002008 name: lumbar vertebra 3 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004619 ! lumbar vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002009 name: lumbar vertebra 3 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 3 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002011 ! lumbar vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002010 name: lumbar vertebra 3 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 3 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002011 ! lumbar vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002011 name: lumbar vertebra 3 height def: "The height of a lumbar vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 3 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004619 ! lumbar vertebra 3 relationship: characteristic_of UBERON:0004619 ! lumbar vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002012 name: lumbar vertebra 4 physiological length def: "The length of the body of a lumbar vertebra 4 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 4 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002013 name: lumbar vertebra 4 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004620 ! lumbar vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002014 name: lumbar vertebra 4 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 4 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002016 ! lumbar vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002015 name: lumbar vertebra 4 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 4 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002016 ! lumbar vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002016 name: lumbar vertebra 4 height def: "The height of a lumbar vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 4 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004620 ! lumbar vertebra 4 relationship: characteristic_of UBERON:0004620 ! lumbar vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002017 name: lumbar vertebra 5 physiological length def: "The length of the body of a lumbar vertebra 5 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 5 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002018 name: lumbar vertebra 5 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:0002828 ! lumbar vertebra 5 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002019 name: lumbar vertebra 5 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 5 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002021 ! lumbar vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002020 name: lumbar vertebra 5 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 5 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002021 ! lumbar vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002021 name: lumbar vertebra 5 height def: "The height of a lumbar vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 5 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height is_a: OBA:0002828 ! lumbar vertebra 5 size intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004621 ! lumbar vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002022 name: mammalian cervical vertebra 3 physiological length def: "The length of the body of a mammalian cervical vertebra 3 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 3 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004612 ! mammalian cervical vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002023 name: mammalian cervical vertebra 3 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004612 ! mammalian cervical vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002024 name: mammalian cervical vertebra 3 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004612 ! mammalian cervical vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002025 name: mammalian cervical vertebra 3 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 3 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004612 ! mammalian cervical vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002026 name: mammalian cervical vertebra 3 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004612 ! mammalian cervical vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002027 name: mammalian cervical vertebra 3 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002029 ! mammalian cervical vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002028 name: mammalian cervical vertebra 3 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002029 ! mammalian cervical vertebra 3 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002029 name: mammalian cervical vertebra 3 height def: "The height of a mammalian cervical vertebra 3 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 3 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004612 ! mammalian cervical vertebra 3 relationship: characteristic_of UBERON:0004612 ! mammalian cervical vertebra 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002030 name: mammalian cervical vertebra 4 physiological length def: "The length of the body of a mammalian cervical vertebra 4 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 4 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004613 ! mammalian cervical vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002031 name: mammalian cervical vertebra 4 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004613 ! mammalian cervical vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002032 name: mammalian cervical vertebra 4 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004613 ! mammalian cervical vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002033 name: mammalian cervical vertebra 4 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004613 ! mammalian cervical vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002034 name: mammalian cervical vertebra 4 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004613 ! mammalian cervical vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002035 name: mammalian cervical vertebra 4 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002037 ! mammalian cervical vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002036 name: mammalian cervical vertebra 4 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002037 ! mammalian cervical vertebra 4 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002037 name: mammalian cervical vertebra 4 height def: "The height of a mammalian cervical vertebra 4 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 4 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004613 ! mammalian cervical vertebra 4 relationship: characteristic_of UBERON:0004613 ! mammalian cervical vertebra 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002038 name: mammalian cervical vertebra 5 physiological length def: "The length of the body of a mammalian cervical vertebra 5 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 5 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004614 ! mammalian cervical vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002039 name: mammalian cervical vertebra 5 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004614 ! mammalian cervical vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002040 name: mammalian cervical vertebra 5 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004614 ! mammalian cervical vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002041 name: mammalian cervical vertebra 5 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 5 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004614 ! mammalian cervical vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002042 name: mammalian cervical vertebra 5 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004614 ! mammalian cervical vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002043 name: mammalian cervical vertebra 5 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002045 ! mammalian cervical vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002044 name: mammalian cervical vertebra 5 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002045 ! mammalian cervical vertebra 5 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002045 name: mammalian cervical vertebra 5 height def: "The height of a mammalian cervical vertebra 5 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 5 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004614 ! mammalian cervical vertebra 5 relationship: characteristic_of UBERON:0004614 ! mammalian cervical vertebra 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002046 name: mammalian cervical vertebra 6 physiological length def: "The length of the body of a mammalian cervical vertebra 6 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 6 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004615 ! mammalian cervical vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002047 name: mammalian cervical vertebra 6 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004615 ! mammalian cervical vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002048 name: mammalian cervical vertebra 6 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004615 ! mammalian cervical vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002049 name: mammalian cervical vertebra 6 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 6 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004615 ! mammalian cervical vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002050 name: mammalian cervical vertebra 6 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004615 ! mammalian cervical vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002051 name: mammalian cervical vertebra 6 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002053 ! mammalian cervical vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002052 name: mammalian cervical vertebra 6 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002053 ! mammalian cervical vertebra 6 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002053 name: mammalian cervical vertebra 6 height def: "The height of a mammalian cervical vertebra 6 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 6 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004615 ! mammalian cervical vertebra 6 relationship: characteristic_of UBERON:0004615 ! mammalian cervical vertebra 6 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002054 name: mammalian cervical vertebra 7 physiological length def: "The length of the body of a mammalian cervical vertebra 7 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "mammalian cervical vertebra 7 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004616 ! mammalian cervical vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002055 name: mammalian cervical vertebra 7 length between cranial and caudal articular processes def: "The length between the cranial and caudal articular processes along the superior-inferior axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest length from the processus articulares craniales to the processus articulares caudales (GLPa)" RELATED [ISBN:9780873659505] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0000122 ! length relationship: characteristic_of UBERON:0004616 ! mammalian cervical vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002056 name: mammalian cervical vertebra 7 cranial articular process breadth def: "The width of the cranial articular surface of a mammalian cervical vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004616 ! mammalian cervical vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002057 name: mammalian cervical vertebra 7 caudal articular process breadth def: "The width of the caudal articular surface of a mammalian cervical vertebra 7 along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004616 ! mammalian cervical vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002058 name: mammalian cervical vertebra 7 transverse process breadth def: "The width between the left and right transverse processes along the medial-lateral axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004616 ! mammalian cervical vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002059 name: mammalian cervical vertebra 7 cranial articular surface height def: "The hieght of the cranial articular surface of a mammalian cervical vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest height of the facies terminalis cranials (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002061 ! mammalian cervical vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002060 name: mammalian cervical vertebra 7 caudal articular surface height def: "The hieght of the caudal articular surface of a mammalian cervical vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002061 ! mammalian cervical vertebra 7 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002061 name: mammalian cervical vertebra 7 height def: "The height of a mammalian cervical vertebra 7 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "mammalian cervical vertebra 7 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001912 ! cervical vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004616 ! mammalian cervical vertebra 7 relationship: characteristic_of UBERON:0004616 ! mammalian cervical vertebra 7 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002062 name: lumbar vertebra 2 physiological length def: "The length of the body of a lumbar vertebra 2 along the superior-inferior axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "lumbar vertebra 2 physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0004048 ! lumbar vertebra length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002063 name: lumbar vertebra 2 transverse process breadth def: "The width between the left and right transverse processes of a lumbar vertebra 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0004618 ! lumbar vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002064 name: lumbar vertebra 2 cranial articular surface height def: "The height of the cranial articular surface of a lumbar vertebra 2 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest height of the facies terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002066 ! lumbar vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002065 name: lumbar vertebra 2 caudal articular surface height def: "The height of the caudal articular surface of a lumbar vertebra 2 along the ventral-dosral axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest height of the facies terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002066 ! lumbar vertebra 2 height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002066 name: lumbar vertebra 2 height def: "The height of a lumbar vertebra 2 along the ventral-dorsal axis." [ISBN:9780873659505] synonym: "lumbar vertebra 2 greatest height (H)" RELATED [ISBN:9780873659505] is_a: FOVT:0001917 ! lumbar vertebra height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004618 ! lumbar vertebra 2 relationship: characteristic_of UBERON:0004618 ! lumbar vertebra 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002067 name: distal phalanx of manual digit 3 articular surface depth def: "The depth of the articular surface on the proximal end of a distal phalax of manual digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 length of the facies articularis (LF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular surface" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9788 [Term] id: FOVT:0002068 name: distal phalanx of manual digit 3 height def: "The height of a distal phalanx of manual digit 3 along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "digit 3 phalanx 3 height in the region of the extensor process (HP)" RELATED [ISBN:9780873659505] synonym: "third phalanx of central digit maximal height (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004312 ! distal phalanx of manual digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9788 [Term] id: FOVT:0002069 name: distal phalanx of pes anterior length def: "The length of the anterior side of a distal phalanx of pes along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "third phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000628 ! distal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002070 name: distal phalanx of pes diaphysis breadth def: "The width of the diaphysis of a distal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third phalanx minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000628 ! distal phalanx of pes quality is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002071 name: distal phalanx of pes distal breadth def: "The width of the distal end of a distal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "third phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002124 ! phalanx of pes distal breadth is_a: OBA:1000628 ! distal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002072 name: distal phalanx of pes proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of pes along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003079 ! distal phalanx of pes size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002073 name: distal phalanx of pes proximal breadth def: "The width of the proximal end of a distal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002126 ! phalanx of pes proximal breadth is_a: OBA:1000628 ! distal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002074 name: distal phalanx of pes proximal depth def: "The depth of the proximal end of a distal phalanx of pes along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000628 ! distal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002075 name: distal phalanx of manus anterior length def: "The length of the anterior side of a distal phalanx of manus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] synonym: "third phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002128 ! phalanx of manus anterior length is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002076 name: distal phalanx of manus diaphysis breadth def: "The width of the diaphysis of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 smallest breadth of the diaphysis (SD)" RELATED [ISBN:9780873659505] synonym: "third phalanx minimal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002587 ! diaphysis size is_a: OBA:1000190 ! distal phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add diaphysis" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002077 name: distal phalanx of manus distal breadth def: "The width of the distal end of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "third phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002129 ! phalanx of manus distal breadth is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002078 name: distal phalanx of manus proximal articular surface breadth def: "The width of the proximal articular surface of a distal phalanx of manus along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the facies articularis proximalis (BFp)" RELATED [ISBN:9780873659505] is_a: OBA:0003006 ! distal phalanx of manus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002079 name: distal phalanx of manus proximal breadth def: "The width of the proximal end of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "third phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002130 ! phalanx of manus proximal breadth is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002080 name: distal phalanx of manus proximal depth def: "The depth of the proximal end of a distal phalanx of manus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002131 ! phalanx of manus proximal depth is_a: OBA:1000190 ! distal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002081 name: distal phalanx of manus articular surface breadth def: "The width of the articular surface of a distal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 breadth of the facies articularis (BF)" RELATED [ISBN:9780873659505] synonym: "third phalanx articular breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003006 ! distal phalanx of manus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002082 name: distal phalanx of manus articular surface depth def: "The depth of the articular surface of a distal phalanx of manus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 length of the facies articularis (LF)" RELATED [ISBN:9780873659505] synonym: "third phalanx articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003006 ! distal phalanx of manus size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002083 name: middle phalanx of manus distal breadth def: "The width of the distal end of a middle phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "second phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002129 ! phalanx of manus distal breadth is_a: OBA:1000382 ! middle phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002084 name: middle phalanx of pes distal breadth def: "The width of the distal end of a middle phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 2 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] synonym: "second phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002124 ! phalanx of pes distal breadth is_a: OBA:1000492 ! middle phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002085 name: proximal phalanx of manus distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003012 ! proximal phalanx of manus size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002086 name: proximal phalanx of manus distal breadth def: "The width of the distal end of a proximal phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002129 ! phalanx of manus distal breadth is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002087 name: proximal phalanx of pes distal articular surface breadth def: "The width of the distal articular surface of a proximal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular breadth (M7)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the facies articularis distalis (BFd)" RELATED [ISBN:9780873659505] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002088 name: proximal phalanx of pes distal breadth def: "The width of the distal end of a proximal phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002124 ! phalanx of pes distal breadth is_a: OBA:1000212 ! proximal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002089 name: obsolete mammalian cervical vertebra physiological length def: "OBSOLETE. The length of the body of a cervical vertebra along the proximal-distal axis." [ISBN:9780873659505] comment: already exists comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "cervical physiological length of the body (PL)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001905 [Term] id: FOVT:0002090 name: obsolete mammalian cervical vertebra length between cranial and caudal articular processes comment: term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001906 [Term] id: FOVT:0002091 name: obsolete mammalian cervical vertebra cranial articular process breadth def: "OBSOLETE. The width of the cranial articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest breadth across the processus articulares craniales (BPacr)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001907 [Term] id: FOVT:0002092 name: obsolete mammalian cervical vertebra caudal articular process breadth def: "OBSOLETE. The width of the caudal articular surface of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest breadth across the processus articulares caudales (BPacd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001908 [Term] id: FOVT:0002093 name: obsolete mammalian cervical vertebra cranial articular surface height def: "OBSOLETE. The height of the cranial articular surface of a cervical vertebra along the dorsal-ventral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest height of the processus terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001910 [Term] id: FOVT:0002094 name: obsolete mammalian cervical vertebra caudal articular surface height def: "OBSOLETE. The height of the caudal articular surface of a cervical vertebra along the dorsal-ventral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest height of the processus terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001911 [Term] id: FOVT:0002095 name: obsolete mammalian cervical vertebra height def: "OBSOLETE. The height of a cervical vertebra along the dorsal-ventral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest height (H)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001912 [Term] id: FOVT:0002096 name: obsolete mammalian cervical vertebra transverse process breadth def: "OBSOLETE. The width between the left and right transverse processes of a cervical vertebra along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "cervical greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0001909 [Term] id: FOVT:0002097 name: metacarpal bone diaphysis depth def: "The depth of the diaphysis of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metacarpal smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0013752 ! diaphysis of metacarpal bone relationship: characteristic_of UBERON:0013752 ! diaphysis of metacarpal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002098 name: metacarpal bone proximal breadth def: "The width of the proximal end of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metacarpal proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002116 ! metapodial bone proximal breadth is_a: OBA:0003763 ! metacarpal bone morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002099 name: metacarpal bone proximal depth def: "The depth of the proximal end of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] synonym: "metacarpal proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002115 ! metapodial bone proximal depth is_a: OBA:0003763 ! metacarpal bone morphology relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002100 name: metacarpal bone distal articular breadth def: "The width of the distal articular of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002101 name: metacarpal bone distal articular depth def: "The depth of the distal articular of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002102 name: metacarpal bone diaphysis breadth def: "The width of the diaphysis of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal minimal breadth (near the middle of the bone) (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metacarpal smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0013752 ! diaphysis of metacarpal bone relationship: characteristic_of UBERON:0013752 ! diaphysis of metacarpal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002103 name: metacarpal bone proximal articular breadth def: "The width of the proximal articular of a metacarpal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metacarpal proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002104 name: metacarpal bone proximal articular depth def: "The depth of the proximal articular of a metacarpal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metacarpal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002105 name: metatarsal bone diaphysis depth def: "The depth of the diaphysis of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal minimal depth of the diaphysis (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal smallest depth of diaphysis (DD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0013774 ! diaphysis of metatarsal bone relationship: characteristic_of UBERON:0013774 ! diaphysis of metatarsal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002106 name: metatarsal bone diaphysis breadth def: "The width of the diaphysis of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal minimal breadth (near the middle of the bone) (M3)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal smallest breadth of diaphysis (SD)" RELATED [ISBN:9780873659505] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0013774 ! diaphysis of metatarsal bone relationship: characteristic_of UBERON:0013774 ! diaphysis of metatarsal bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002107 name: metatarsal bone proximal breadth def: "The width of the proximal end of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metatarsal proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002116 ! metapodial bone proximal breadth is_a: OBA:VT0003072 ! metatarsus morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002108 name: metatarsal bone proximal depth def: "The depth of the proximal end of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metatarsal greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002115 ! metapodial bone proximal depth is_a: OBA:VT0003072 ! metatarsus morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002109 name: metatarsal bone distal articular breadth def: "The width of the distal articular of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002110 name: metatarsal bone distal articular depth def: "The depth of the distal articular of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002111 name: metatarsal bone proximal articular breadth def: "The width of the proximal articular of a metatarsal bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metatarsal greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metatarsal proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002112 name: metatarsal bone proximal articular depth def: "The depth of the proximal articular of a metatarsal bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metatarsal proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002251 ! metatarsal bone size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002113 name: metapodial bone proximal articular depth def: "The depth of the proximal articular of a metapodial bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metapodial proximal articular depth (M6)" RELATED [ISBN:9004086161\, 9789004086166] is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003821 ! metapodium bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002114 name: metapodial bone proximal articular breadth def: "The width of the proximal articular of a metapodial bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metapodial greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metapodial proximal articular breadth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003821 ! metapodium bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002115 name: metapodial bone proximal depth def: "The depth of the proximal end of a metapodial bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metacarpal proximal maximal depth (M4)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "metapodial greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002116 name: metapodial bone proximal breadth def: "The width of the proximal end of a metapodial bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "metapodial greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "metapodial proximal maximal breadth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002117 name: metapodial bone distal articular breadth def: "The width of the distal articular of a metapodial bone along the medial-lateral axis." [ISBN:9004086161\, 9789004086166] synonym: "metapodial distal maximal articular breadth (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: PATO:0000921 ! width relationship: characteristic_of UBERON:0003821 ! metapodium bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002118 name: metapodial bone distal articular depth def: "The depth of the distal articular of a metapodial bone along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "metapodial distal articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0003821 ! metapodium bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add articular" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002119 name: phalanx distal breadth def: "The width of the distal end of a phalanx along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002120 name: obsolete phalanx distal distal articular breadth comment: not needed relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true [Term] id: FOVT:0002121 name: phalanx anterior length def: "The length of the anterior side of a phalanx along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002122 name: phalanx proximal breadth def: "The width of the proximal end of a phalanx along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002123 name: phalanx proximal depth def: "The depth of the proximal end of a phalanx along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002124 name: phalanx of pes distal breadth def: "The width of the distal end of a phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002119 ! phalanx distal breadth is_a: OBA:1000501 ! phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002125 name: phalanx of pes anterior length def: "The length of the anterior side of a phalanx of pes along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000492 ! middle phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002126 name: phalanx of pes proximal breadth def: "The width of the proximal end of a phalanx of pes along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002122 ! phalanx proximal breadth is_a: OBA:1000501 ! phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002127 name: phalanx of pes proximal depth def: "The depth of the proximal end of a phalanx of pes along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000492 ! middle phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002128 name: phalanx of manus anterior length def: "The length of the anterior side of a phalanx of manus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002129 name: phalanx of manus distal breadth def: "The width of the distal end of a phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx distal articular maximal breadth (M6)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx greatest breadth of the distal end (Bd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002119 ! phalanx distal breadth is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002130 name: phalanx of manus proximal breadth def: "The width of the proximal end of a phalanx of manus along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx greatest breadth of the proximal end (Bp)" RELATED [ISBN:9780873659505] synonym: "phalanx proximal breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002122 ! phalanx proximal breadth is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002131 name: phalanx of manus proximal depth def: "The depth of the proximal end of a phalanx of manus along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "phalanx proximal maximal depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002123 ! phalanx proximal depth is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002132 name: vertebra height def: "The height of a vertebra along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "vertebra greatest height (H)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0002412 ! vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002133 name: vertebra physiological length def: "The length of a vertebra body along the proximal-distal axis." [ISBN:9780873659505] comment: This is measured between the centers of the facies terminalis cranialis and the facies terminalis caudalis. {xref="ISBN:9780873659505"} synonym: "vertebra physiological length of the body (PL)" RELATED [ISBN:9780873659505] is_a: OBA:0002823 ! vertebra size is_a: PATO:0000122 ! length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002134 name: vertebra transverse process breadth def: "The width between the left and right transverse processes of a vertebra along the medial-lateral axis." [ISBN:9780873659505] synonym: "vertebra greatest breadth across the processus transversi (BPtr)" RELATED [ISBN:9780873659505] is_a: OBA:1000675 ! transverse process of vertebra quality is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001077 ! transverse process of vertebra relationship: characteristic_of UBERON:0001077 ! transverse process of vertebra relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: editor_note "need to add transverse process" xsd:string property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002135 name: vertebra cranial articular surface height def: "The height of the cranial articular surface of a vertebra along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "vertebra greatest height of the processus terminalis cranialis (HFcr)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002136 name: vertebra caudal articular surface height def: "The height of the caudal articular surface of a vertebra along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "vertebra greatest height of the processus terminalis caudalis (HFcd)" RELATED [ISBN:9780873659505] is_a: FOVT:0002132 ! vertebra height relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002137 name: proximal phalanx of manus anterior length def: "The length of the anterior side of a phalanx of manus along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002128 ! phalanx of manus anterior length is_a: OBA:1000610 ! proximal phalanx of manus quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002138 name: proximal phalanx of pes anterior length def: "The length of the anterior side of a phalanx of pes along the proximal-distal axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "first phalanx anterior length (M2)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "phalanx 1 greatest length of peripheral half (GLpe)" RELATED [ISBN:9780873659505] is_a: FOVT:0002121 ! phalanx anterior length is_a: OBA:1000212 ! proximal phalanx of pes quality relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002139 name: metatarsal bone of digit 3 diaphysis circumference def: "The circumference of the diaphysis of a metatarsal bone of digit 3." [ISBN:9780873659505] synonym: "metatarsal III smallest circumference of hte diaphysis (CD)" RELATED [ISBN:9780873659505] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000413 ! metatarsal bone of digit 3 quality is_a: PATO:0001648 ! circumference relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002140 name: metacarpal bone of digit 3 proximal depth def: "IAO:0000423" [] def: "The depth of the proximal end of a metacarpal bone of digit 3 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "metacarpal III greatest depth of the proximal end (Dp)" RELATED [ISBN:9780873659505] is_a: FOVT:0002099 ! metacarpal bone proximal depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: FOVT:0002141 name: distal phalanx of manual digit 3 circumference def: "The circumference of a distal phalanx of manual digit 3." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of the central digit circumference of the sole (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002143 ! distal phalanx of digit 3 circumference is_a: OBA:0002939 ! distal phalanx of manual digit 3 size intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0004312 ! distal phalanx of manual digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002142 name: distal phalanx of pedal digit 3 circumference def: "The circumference of a distal phalanx of pedal digit 3." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of the central digit circumference of the sole (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002143 ! distal phalanx of digit 3 circumference is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002143 name: distal phalanx of digit 3 circumference def: "The circumference of a distal phalanx of digit 3." [ISBN:9004086161\, 9789004086166] synonym: "third phalanx of the central digit circumference of the sole (M8)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002674 ! phalanx size is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0014485 ! distal phalanx of digit 3 relationship: characteristic_of UBERON:0014485 ! distal phalanx of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002144 name: distal phalanx of manual digit 2 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of manual digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002966 ! distal phalanx of manual digit 2 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002145 name: distal phalanx of pedal digit 2 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002172 ! distal phalanx of pedal digit 2 depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002146 name: distal phalanx of digit 2 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of digit 2 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002674 ! phalanx size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0014484 ! distal phalanx of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002147 name: distal phalanx of manual digit 2 diagonal length def: "The length of the distal phalanx of manual digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:0002970 ! distal phalanx of manual digit 2 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002148 name: distal phalanx of pedal digit 2 diagonal length def: "The length of the distal phalanx of pedal digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: FOVT:0001820 ! distal phalanx of pedal digit 2 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002149 name: distal phalanx of digit 2 diagonal length def: "The length of the distal phalanx of digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:VT0002543 ! phalanx length relationship: characteristic_of UBERON:0014484 ! distal phalanx of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002150 name: distal phalanx of manual digit 2 middle breadth def: "The width of the middle of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002153 ! distal phalanx of manual digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002151 name: distal phalanx of pedal digit 2 middle breadth def: "The width of the middle of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002154 ! distal phalanx of pedal digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002152 name: distal phalanx of digit 2 middle breadth def: "The width of the middle of a distal phalanx of digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002155 ! distal phalanx of digit 2 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002153 name: distal phalanx of manual digit 2 breadth def: "The width of a distal phalanx of manual digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002155 ! distal phalanx of digit 2 breadth is_a: OBA:0002966 ! distal phalanx of manual digit 2 size intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004311 ! distal phalanx of manual digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002154 name: distal phalanx of pedal digit 2 breadth def: "The width of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002155 ! distal phalanx of digit 2 breadth is_a: OBA:0003135 ! distal phalanx of pedal digit 2 size intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002155 name: distal phalanx of digit 2 breadth def: "The width of a distal phalanx of digit 2 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0002674 ! phalanx size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0014484 ! distal phalanx of digit 2 relationship: characteristic_of UBERON:0014484 ! distal phalanx of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002156 name: distal phalanx of digit 4 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002674 ! phalanx size is_a: PATO:0001595 ! depth relationship: characteristic_of UBERON:0014486 ! distal phalanx of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002157 name: distal phalanx of manual digit 4 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of manual digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002919 ! distal phalanx of manual digit 4 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002158 name: distal phalanx of pedal digit 4 proximal articular depth def: "The depth of the proximal articular surface of a distal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "proximal articular depth (M3)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:0002174 ! distal phalanx of pedal digit 4 depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002159 name: distal phalanx of manual digit 4 diagonal length def: "The length of the distal phalanx of manual digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:0002918 ! distal phalanx of manual digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002160 name: distal phalanx of pedal digit 4 diagonal length def: "The length of the distal phalanx of pedal digit 4 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: FOVT:0001807 ! distal phalanx of pedal digit 4 length relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002161 name: distal phalanx of digit 4 diagonal length def: "The length of the distal phalanx of digit 2 along the proximal-distal axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest diagonal length of the sole (DLS)" RELATED [ISBN:9780873659505] is_a: OBA:VT0002543 ! phalanx length relationship: characteristic_of UBERON:0014486 ! distal phalanx of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002162 name: distal phalanx of manual digit 4 middle breadth def: "The width of the middle of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002166 ! distal phalanx of manual digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002163 name: distal phalanx of pedal digit 4 middle breadth def: "The width of the middle of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002165 ! distal phalanx of pedal digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002164 name: distal phalanx of digit 4 middle breadth def: "The width of the middle of a distal phalanx of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 middle breadth of the sole (MBS)" RELATED [ISBN:9780873659505] is_a: FOVT:0002167 ! distal phalanx of digit 4 breadth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002165 name: distal phalanx of pedal digit 4 breadth def: "The width of a distal phalanx of pedal digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002167 ! distal phalanx of digit 4 breadth is_a: OBA:0003367 ! distal phalanx of pedal digit 4 size intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002166 name: distal phalanx of manual digit 4 breadth def: "The width of a distal phalanx of manual digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: FOVT:0002167 ! distal phalanx of digit 4 breadth is_a: OBA:0002919 ! distal phalanx of manual digit 4 size intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004313 ! distal phalanx of manual digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002167 name: distal phalanx of digit 4 breadth def: "The width of a distal phalanx of digit 4 along the medial-lateral axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0002674 ! phalanx size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0014486 ! distal phalanx of digit 4 relationship: characteristic_of UBERON:0014486 ! distal phalanx of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002168 name: distal phalanx of pedal digit 3 articular breadth def: "The width of the articular surface of a distal phalanx of pedal digit 3 along the medial-lateral axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalnx 3 breadth of the facies articularis (BF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of the central digit articular breadth (M4)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0000921 ! width relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002169 name: distal phalanx of pedal digit 3 articular depth def: "The depth of the articular surface of a distal phalanx of pedal digit 3 along the anterior-posterior axis." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] synonym: "phalanx 3 length of the facies articularis (LF)" RELATED [ISBN:9780873659505] synonym: "third phalanx of the central digit articular depth (M5)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0001595 ! depth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002170 name: distal phalanx of pedal digit 3 height def: "The height of a distal phalanx of pedal digit 3 along the dorsal-ventral axis." [ISBN:9780873659505] synonym: "phalanx 3 height in the region of the extensor process (HP)" RELATED [ISBN:9780873659505] is_a: OBA:0003366 ! distal phalanx of pedal digit 3 size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002171 name: obsolete distal phalanx of pedal digit 3 circumference comment: term already exists relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 is_obsolete: true replaced_by: FOVT:0002143 [Term] id: FOVT:0002172 name: distal phalanx of pedal digit 2 depth def: "The depth of a distal phalanx of pedal digit 2 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "phalanx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0003135 ! distal phalanx of pedal digit 2 size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002173 name: navicular breadth def: "The width of a navicular along the medial-lateral axis." [ISBN:9780873659505] synonym: "navicular greatest breadth (GB)" RELATED [ISBN:9780873659505] is_a: OBA:0004840 ! navicular bone of pes morphology is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001451 ! navicular bone of pes relationship: characteristic_of UBERON:0001451 ! navicular bone of pes relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002174 name: distal phalanx of pedal digit 4 depth def: "The depth of a distal phalanx of pedal digit 4 along the anterior-posterior axis." [ISBN:9780873659505] synonym: "phalnx 3 greatest length (GL)" RELATED [ISBN:9780873659505] is_a: OBA:0003367 ! distal phalanx of pedal digit 4 size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:0002175 name: obsolete distal phalanx of pedal digit 2 breadth def: "OBSOLETE. The width of a distal phalanx of pedal digit 2 along the medial-lateral axis." [ISBN:9780873659505] comment: already exists synonym: "phalanx 3 greatest breadth (GB)" RELATED [ISBN:9780873659505] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: IAO:0000114 IAO:0000423 is_obsolete: true replaced_by: FOVT:0002154 [Term] id: FOVT:2000000 name: choana length def: "The length of a posterior nasal aperture of the interal naris (choana) along anterior-posterior axis." [ISBN:9004086161\, 9789004086166] synonym: "choanal length (M10)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0002236 ! internal nares morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004771 ! posterior nasal aperture relationship: characteristic_of UBERON:0004771 ! posterior nasal aperture property_value: http://purl.org/dc/elements/1.1/contributor "https://orcid.org/0000-0001-8415-4848" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000001 name: choana minimal breadth def: "The length of the posterior portion of a posterior nasal aperture of the internal naris (choana) along left-right axis." [ISBN:9004086161\, 9789004086166] synonym: "choana minimal width" EXACT [] synonym: "minimal breadth of the choanae (M11)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0002236 ! internal nares morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width property_value: http://purl.org/dc/elements/1.1/contributor "https://orcid.org/0000-0001-8415-4848" xsd:string property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000002 name: choana maximal breadth def: "The length along the midline of a posterior nasal aperture of the internal naris (choana) along left-right axis." [ISBN:9004086161\, 9789004086166] synonym: "choanal maximal width" EXACT [] synonym: "maximal breadth of the choanae (M12)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0002236 ! internal nares morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0004771 ! posterior nasal aperture relationship: characteristic_of UBERON:0004771 ! posterior nasal aperture relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000003 name: muzzle minimal breadth def: "The length of a muzzle between the middle of the right and left diastema of an upper jaw." [ISBN:9004086161\, 9789004086166, ISBN:9780873659505] comment: This is measurement 47 for Equus in von den Driesch (1979). {xref="ISBN:9780873659505"} synonym: "least breadth in the region of the diastema" RELATED [ISBN:9780873659505] synonym: "minimal muzzle breadth (M14)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "muzzle minimal width" EXACT [] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:VT0000443 ! snout morphology trait is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0006333 ! snout relationship: characteristic_of UBERON:0006333 ! snout relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000004 name: supraoccipital crest length def: "The length of a supraoccipital crest along the left-right axis." [ISBN:9004086161\, 9789004086166] synonym: "occipital breadth (M20)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003980 ! supraoccipital bone size is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0010517 ! neurocranium size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:2001783 ! supraoccipital crest relationship: characteristic_of UBERON:2001783 ! supraoccipital crest relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000005 name: foramen magnum breadth def: "The length of a foramen magnum along the left-right axis." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 36 Equus, 21 Camelus, 28 Bos, 29 Ovis and Capra, 28 Cervus, 36 Sus, 27 Canis and Ursus, 20 Felis. {xref="ISBN:9780873659505"} synonym: "foramen magnum width" EXACT [] synonym: "greatest breadth of foramen magnum" RELATED [ISBN:9780873659505] is_a: OBA:0002346 ! foramen magnum size is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0003687 ! foramen magnum relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000006 name: foramen magnum height def: "The length of a foramen magnum along the midsagittal plane." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 37 Equus, 22 Camelus, 29 Bos, 30 Ovis and Capra, 29 Cervus, 37 Sus, 28 Canis and Ursus, 21 Felis. {xref="ISBN:9780873659505"} synonym: "height of the foramen magnum" RELATED [ISBN:9780873659505] is_a: OBA:0002346 ! foramen magnum size is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0003687 ! foramen magnum relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: FOVT:2000007 name: occipital breadth def: "The length between the right and left temporal fossa of the occipital region of a skull." [ISBN:9780873659505] comment: This is measurement 30 for Bos in von den Driesch (1979). {xref="ISBN:9780873659505"} synonym: "least occipital breadth" RELATED [ISBN:9780873659505] synonym: "occipital width" EXACT [] is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0005902 ! occipital region relationship: characteristic_of UBERON:0005902 ! occipital region relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000008 name: basicranium length def: "The length of a basicranium." [ISBN: 9780873659505] is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000009 name: basicranium length from hormion def: "The length of a basicranium from a hormion to a basion." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The measurement number and genus in von den Driesch (1979): 5 Equus, 5 Camelus, 6 Sus. synonym: "basicranial axis to hormion length" RELATED [ISBN: 9780873659505] synonym: "post-vomerine length (M4)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000008 ! basicranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 [Term] id: FOVT:2000010 name: basicranium length from synsphenion def: "The length of a skull from synsphenion to basion." [ISBN: 9780873659505] comment: The measurement number and genus from von den Driesch (1979): 6 Cervus, 4 Canis and Ursus, 4 Felis. {xref="ISBN: 9780873659505"} synonym: "basicranial axis to synphenion length" RELATED [ISBN: 9780873659505] is_a: FOVT:2000008 ! basicranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9859 [Term] id: FOVT:2000011 name: bony part of hard palate breadth def: "The length of a bony part of hard palate along the left-right axis." [ISBN: 9004086161\, 9789004086166] comment: bony part of hard palate width synonym: "palatal breadth (M13)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:0003100 ! hard palate size is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0012074 ! bony part of hard palate relationship: characteristic_of UBERON:0012074 ! bony part of hard palate relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000012 name: bony part of hard palate length def: "The length of a bony part of a hard palate along the left-right axis." [ISBN: 9004086161\, 9789004086166] comment: This measurement is taken along the midsagittal plane afrom the anteriormost part of the cheekteeth to a anteriormost part of the choanal groove. synonym: "palatal length (M2)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000014 ! post-palatal length is_a: OBA:0002546 ! facial skeleton size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0012074 ! bony part of hard palate relationship: characteristic_of UBERON:0012074 ! bony part of hard palate relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000013 name: vomer ventral length def: "The length of a vomer from anteriormost part of a choanal groove to a hormion." [ISBN: 9004086161\, 9789004086166] synonym: "vomerine length (M2)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: OBA:0002546 ! facial skeleton size is_a: OBA:0004900 ! vomer size is_a: OBA:VT0003104 ! skull size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002396 ! vomer relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 [Term] id: FOVT:2000014 name: post-palatal length def: "The length of a line from choanal groove to basion of a cranium." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The measurement number and genus from von den Driesch (1979) are: 17 Equus, 9 Camelus, 16 Sus. {xref="ISBN: 9780873659505"} synonym: "basion to staphylion length" RELATED [ISBN: 9780873659505] synonym: "post-palatal length (M5)" RELATED [ISBN: 9004086161\, 9789004086166] is_a: OBA:0003100 ! hard palate size is_a: OBA:VT0003104 ! skull size trait is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003216 ! hard palate relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 [Term] id: FOVT:2000015 name: occipital region height from opisthion def: "The length of an occipital region from an opisthion to an akrocranion." [ISBN: 9780873659505, ISBN:9004086161\, 9789004086166] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 41 Bos. {xref="ISBN: 9780873659505"} synonym: "least height of the occipital region" RELATED [ISBN:9780873659505] synonym: "occipital height (M22)" RELATED [ISBN:9004086161\, 9789004086166] is_a: FOVT:2000020 ! occipital region height relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000016 name: occipital region height from basion def: "The length of an occipital region from a basion to an akrokranion" [ISBN: 9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 50 Equus, 30 Camelus, 40 Bos, 38 Cervus, 38 Canis and Ursus. {xref="ISBN: 9780873659505"} synonym: "basion height" RELATED [] synonym: "cranial height (M26)" RELATED [ISBN:9004086161\, 9789004086166] synonym: "skull height" RELATED [] is_a: FOVT:2000020 ! occipital region height relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 [Term] id: FOVT:2000017 name: cranium dorsal length def: "The length of the dorsal side of a cranium along the anterior-posterior axis." [ISBN:9780873659505] comment: In pigs, the dorsalmost point, the opisthocranion, is projected into space. {xref="ISBN:9780873659505"} comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 1 Equus, 1 Camelus, 1 Bos, 1 Ovis and Capra, 1 Cervus, 1 Sus, 1 Canis and Ursus, 1 Felis, 1 Lepus and Oryctolagus {xref="ISBN:9780873659505"} synonym: "cranium greatest length" RELATED [ISBN:9780873659505] synonym: "cranium profile length" RELATED [ISBN:9780873659505] synonym: "cranium total length" RELATED [ISBN:9780873659505] is_a: OBA:0005564 ! cranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000018 name: cranium ventral length from occipital condyle def: "The length of the ventral side of a cranium from an occipital condyle to a prosthion." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 2 Equus, 2 Camelus, 2 Bos, 2 Ovis and Capra, 2 Cervus, 2 Sus, 2 Canis and Ursus, 2 Felis, 2 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "condylobasal length" RELATED [ISBN:9780873659505] is_a: OBA:0005564 ! cranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000019 name: cranium ventral length from basion def: "The length of the ventral side of a cranium from a basion to a prosthion." [ISBN:9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 3 Equus, 3 Camelus, 3 Bos, 3 Ovis and Capra, 3 Cervus, 3 Sus, 3 Canis and Ursus, 3 Felis, 3 Lepus and Oryctolagus. {xref="ISBN:9780873659505"} synonym: "basal length" RELATED [ISBN:9780873659505] is_a: OBA:0005564 ! cranium length relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000020 name: occipital region height def: "The length of an occipital region along the midsagittal axis." [ISBN: 9780873659505] is_a: OBA:VT0005273 ! cranial base morphology trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0005902 ! occipital region relationship: characteristic_of UBERON:0005902 ! occipital region relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000021 name: cranium breadth def: "The breadth of a skull." [] is_a: OBA:VT0010613 ! cranium size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0003128 ! cranium relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 [Term] id: FOVT:2000022 name: cranium breadth at ectorbitale def: "The length of a cranium between the right and left ectorbitale." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: in Lepus and Oryctolagus: breadth at temporal fossae dorsal of the zygomatic processes of the temporal bone {xref="ISBN: 9004086161, 9789004086166"} comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 41 Equus, 25 Camelus, 33 Bos, 34 Ovis and Capra, 32 Cervus, 41 Sus, 32 Canis and Ursus, 24 Felis. synonym: "ectorbitale to ectorbitale" RELATED [ISBN: 9004086161\, 9789004086166] synonym: "frontal breadth (M18)" RELATED [ISBN: 9780873659505] synonym: "greatest breadth across orbits" RELATED [ISBN: 9004086161\, 9789004086166] synonym: "greatest breadth of skull" RELATED [ISBN: 9004086161\, 9789004086166] synonym: "greatest frontal breadth" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:338152 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 property_value: measured_in_taxon NCBITaxon:9980 property_value: measured_in_taxon NCBITaxon:9984 [Term] id: FOVT:2000023 name: cranium breadth at zygomatic arch def: "The length of a cranium from a left to a right zygion." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 34 Cervus, 43 Sus, 30 Canis and Ursus, 23 Felis. {xref="ISBN: 9004086161, 9789004086166"} synonym: "bizygomatic breadth (M19)" RELATED [ISBN: 9780873659505] synonym: "zygomatic breadth" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9682 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9859 [Term] id: FOVT:2000024 name: cranium breadth at paroccipital process def: "The length of a cranium from a left to a right paroccipital process." [ISBN: 9004086161\, 9789004086166, ISBN: 9780873659505] comment: The following is the measurement number and genus for this trait in von den Driesch (1979): 35 Equus, 20 Camelus, 27 Bos, 28 Ovis and Capra, 27 Cervus, 35 Sus, 26 Canis, 26 Ursus. {xref="ISBN: 9004086161, 9789004086166"} synonym: "basioccipital breadth (M21)" RELATED [ISBN: 9780873659505] synonym: "greatest breadth at the bases of the paraoccipital processes" RELATED [ISBN: 9004086161\, 9789004086166] is_a: FOVT:2000021 ! cranium breadth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 property_value: IAO:0000114 IAO:0000423 property_value: measured_in_taxon NCBITaxon:9611 property_value: measured_in_taxon NCBITaxon:9639 property_value: measured_in_taxon NCBITaxon:9789 property_value: measured_in_taxon NCBITaxon:9822 property_value: measured_in_taxon NCBITaxon:9836 property_value: measured_in_taxon NCBITaxon:9859 property_value: measured_in_taxon NCBITaxon:9903 property_value: measured_in_taxon NCBITaxon:9922 property_value: measured_in_taxon NCBITaxon:9935 [Term] id: GO:0000003 name: reproduction namespace: biological_process alt_id: GO:0019952 alt_id: GO:0050876 def: "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." [GOC:go_curators, GOC:isa_complete, GOC:jl, ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_pir subset: goslim_plant synonym: "reproductive physiological process" EXACT [] xref: Wikipedia:Reproduction is_a: GO:0008150 ! biological_process [Term] id: GO:0000011 name: vacuole inheritance namespace: biological_process def: "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." [GOC:mcc, PMID:10873824, PMID:14616069] is_a: GO:0007033 ! vacuole organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: results_in_distribution_of GO:0005773 ! vacuole relationship: results_in_distribution_of GO:0005773 ! vacuole property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0000070 name: mitotic sister chromatid segregation namespace: biological_process alt_id: GO:0016359 def: "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." [GOC:ai, GOC:jl] subset: goslim_pombe synonym: "mitotic chromosome segregation" EXACT [] synonym: "mitotic sister-chromatid adhesion release" NARROW [] is_a: GO:0000819 ! sister chromatid segregation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0140014 ! mitotic nuclear division relationship: part_of GO:0140014 ! mitotic nuclear division [Term] id: GO:0000139 name: Golgi membrane namespace: cellular_component def: "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." [GOC:mah] synonym: "Golgi apparatus membrane" EXACT [] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005794 ! Golgi apparatus relationship: bounding_layer_of GO:0005794 ! Golgi apparatus relationship: part_of GO:0005794 ! Golgi apparatus [Term] id: GO:0000226 name: microtubule cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] subset: goslim_pombe synonym: "microtubule cytoskeleton organisation" EXACT [GOC:mah] synonym: "microtubule cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007017 ! microtubule-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0015630 ! microtubule cytoskeleton relationship: results_in_organization_of GO:0015630 ! microtubule cytoskeleton property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI [Term] id: GO:0000228 name: nuclear chromosome namespace: cellular_component def: "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." [GOC:dph, GOC:mah] subset: goslim_chembl subset: goslim_generic synonym: "nuclear interphase chromosome" NARROW [] is_a: GO:0005694 ! chromosome intersection_of: GO:0005694 ! chromosome intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0031981 ! nuclear lumen [Term] id: GO:0000271 name: polysaccharide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:go_curators] synonym: "glycan biosynthesis" EXACT [] synonym: "glycan biosynthetic process" EXACT [] synonym: "polysaccharide anabolism" EXACT [] synonym: "polysaccharide biosynthesis" EXACT [] synonym: "polysaccharide formation" EXACT [] synonym: "polysaccharide synthesis" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0016051 ! carbohydrate biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18154 ! polysaccharide relationship: has_primary_output CHEBI:18154 ! polysaccharide [Term] id: GO:0000272 name: polysaccharide catabolic process namespace: biological_process alt_id: GO:0044244 def: "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [PMID:33139480] synonym: "multicellular organismal polysaccharide catabolic process" NARROW [] synonym: "polysaccharide breakdown" EXACT [] synonym: "polysaccharide catabolism" EXACT [] synonym: "polysaccharide degradation" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016052 ! carbohydrate catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide [Term] id: GO:0000278 name: mitotic cell cycle namespace: biological_process alt_id: GO:0007067 def: "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." [GOC:mah, ISBN:0815316194, Reactome:69278] comment: Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_yeast synonym: "mitosis" RELATED [] xref: Wikipedia:Mitosis is_a: GO:0007049 ! cell cycle intersection_of: GO:0007049 ! cell cycle intersection_of: has_part GO:0140014 ! mitotic nuclear division relationship: has_part GO:0140014 ! mitotic nuclear division relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0000280 name: nuclear division namespace: biological_process def: "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." [GOC:mah] subset: goslim_pir synonym: "karyokinesis" RELATED [] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: results_in_fission_of GO:0005634 ! nucleus relationship: results_in_fission_of GO:0005634 ! nucleus [Term] id: GO:0000313 name: organellar ribosome namespace: cellular_component def: "A ribosome contained within a subcellular membrane-bounded organelle." [GOC:mah, GOC:mcc] is_a: GO:0005840 ! ribosome intersection_of: GO:0005840 ! ribosome intersection_of: part_of GO:0043226 ! organelle relationship: part_of GO:0043226 ! organelle [Term] id: GO:0000578 name: embryonic axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo." [GOC:dph, GOC:go_curators, GOC:sdb_2009, GOC:tb] synonym: "embryonic axis determination" RELATED [] is_a: GO:0009798 ! axis specification is_a: GO:0009880 ! embryonic pattern specification [Term] id: GO:0000740 name: nuclear membrane fusion namespace: biological_process def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus." [GOC:elh] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: results_in_fusion_of GO:0031965 ! nuclear membrane relationship: results_in_fusion_of GO:0031965 ! nuclear membrane [Term] id: GO:0000741 name: karyogamy namespace: biological_process alt_id: GO:0007335 def: "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." [GOC:elh] synonym: "nuclear fusion" EXACT [] synonym: "nuclear fusion during karyogamy" EXACT [] xref: Wikipedia:Karyogamy is_a: GO:0006997 ! nucleus organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0048284 ! organelle fusion intersection_of: results_in_fusion_of GO:0005634 ! nucleus relationship: part_of GO:0006997 ! nucleus organization relationship: results_in_fusion_of GO:0005634 ! nucleus [Term] id: GO:0000768 name: syncytium formation by plasma membrane fusion namespace: biological_process def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mtg_muscle, GOC:tb] synonym: "cell fusion" BROAD [] is_a: GO:0006949 ! syncytium formation is_a: GO:0140253 ! cell-cell fusion intersection_of: GO:0006949 ! syncytium formation intersection_of: has_part GO:0045026 ! plasma membrane fusion [Term] id: GO:0000785 name: chromatin namespace: cellular_component alt_id: GO:0000789 alt_id: GO:0000790 alt_id: GO:0005717 def: "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." [GOC:elh, PMID:20404130] comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. synonym: "chromosome scaffold" RELATED [] synonym: "cytoplasmic chromatin" NARROW [] synonym: "nuclear chromatin" NARROW [] xref: NIF_Subcellular:sao1615953555 is_a: GO:0032993 ! protein-DNA complex relationship: part_of GO:0005694 ! chromosome [Term] id: GO:0000792 name: heterochromatin namespace: cellular_component alt_id: GO:0005720 alt_id: GO:0035328 def: "A compact and highly condensed form of chromatin that is refractory to transcription." [PMID:32017156] synonym: "nuclear heterochromatin" NARROW [] synonym: "transcriptionally inactive chromatin" EXACT [] synonym: "transcriptionally silent chromatin" EXACT [] xref: NIF_Subcellular:sao581845896 xref: Wikipedia:Heterochromatin is_a: GO:0000785 ! chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22355" xsd:anyURI [Term] id: GO:0000819 name: sister chromatid segregation namespace: biological_process def: "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." [GOC:ai, GOC:elh] is_a: GO:0051276 ! chromosome organization is_a: GO:0098813 ! nuclear chromosome segregation [Term] id: GO:0000902 name: cell morphogenesis namespace: biological_process alt_id: GO:0007148 alt_id: GO:0045790 alt_id: GO:0045791 def: "The developmental process in which the size or shape of a cell is generated and organized." [GOC:clt, GOC:dph, GOC:go_curators, GOC:tb] subset: goslim_chembl subset: goslim_drosophila subset: goslim_yeast synonym: "cellular morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000000 ! cell relationship: results_in_morphogenesis_of CL:0000000 ! cell [Term] id: GO:0000904 name: cell morphogenesis involved in differentiation namespace: biological_process def: "The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:go_curators] is_a: GO:0000902 ! cell morphogenesis intersection_of: GO:0000902 ! cell morphogenesis intersection_of: part_of GO:0048468 ! cell development relationship: part_of GO:0048468 ! cell development [Term] id: GO:0001101 name: response to acid chemical namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." [GOC:go_curators, GOC:rn] comment: This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead. subset: gocheck_do_not_manually_annotate synonym: "response to acid" BROAD [] synonym: "response to acid anion" RELATED [] synonym: "response to oxoanion" RELATED [] is_a: GO:0042221 ! response to chemical [Term] id: GO:0001501 name: skeletal system development namespace: biological_process def: "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." [GOC:dph, GOC:jid, GOC:tb] synonym: "skeletal development" EXACT [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001434 ! skeletal system relationship: results_in_development_of UBERON:0001434 ! skeletal system [Term] id: GO:0001503 name: ossification namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:mtg_mpo, PMID:17572649] comment: Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'. synonym: "bone biosynthesis" EXACT [] synonym: "bone formation" EXACT [] synonym: "osteogenesis" EXACT [] xref: Wikipedia:Ossification is_a: GO:0032501 ! multicellular organismal process intersection_of: GO:0032501 ! multicellular organismal process intersection_of: results_in_formation_of UBERON:0001474 ! bone element relationship: results_in_formation_of UBERON:0001474 ! bone element [Term] id: GO:0001505 name: regulation of neurotransmitter levels namespace: biological_process def: "Any process that modulates levels of neurotransmitter." [GOC:jl] [Term] id: GO:0001508 name: action potential namespace: biological_process def: "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." [GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] comment: Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so. is_a: GO:0042391 ! regulation of membrane potential property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0001525 name: angiogenesis namespace: biological_process def: "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." [ISBN:0878932453] synonym: "blood vessel formation from pre-existing blood vessels" EXACT systematic_synonym [] xref: Wikipedia:Angiogenesis is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001981 ! blood vessel relationship: part_of GO:0048514 ! blood vessel morphogenesis relationship: results_in_formation_of UBERON:0001981 ! blood vessel [Term] id: GO:0001539 name: cilium or flagellum-dependent cell motility namespace: biological_process def: "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." [GOC:cilia, GOC:hjd, GOC:krc] comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "ciliary or bacterial-type flagellar motility" RELATED [] synonym: "ciliary/flagellar motility" EXACT [] is_a: GO:0048870 ! cell motility [Term] id: GO:0001553 name: luteinization namespace: biological_process def: "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] synonym: "luteal phase" RELATED [] xref: Wikipedia:Luteal_phase xref: Wikipedia:Luteinization is_a: GO:0022602 ! ovulation cycle process relationship: part_of GO:0008585 ! female gonad development [Term] id: GO:0001555 name: oocyte growth namespace: biological_process def: "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [https://www.ncbi.nlm.nih.gov/books/NBK279054/] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: results_in_growth_of CL:0000023 ! oocyte [Term] id: GO:0001556 name: oocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." [GOC:devbiol, https://www.ncbi.nlm.nih.gov/books/NBK279054/] xref: Wikipedia:Oocyte_maturation is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: results_in_maturation_of CL:0000023 ! oocyte [Term] id: GO:0001558 name: regulation of cell growth namespace: biological_process def: "Any process that modulates the frequency, rate, extent or direction of cell growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016049 ! cell growth relationship: regulates GO:0016049 ! cell growth [Term] id: GO:0001568 name: blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." [GOC:hjd, UBERON:0001981] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001981 ! blood vessel relationship: part_of GO:0001944 ! vasculature development relationship: results_in_development_of UBERON:0001981 ! blood vessel [Term] id: GO:0001569 name: branching involved in blood vessel morphogenesis namespace: biological_process def: "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." [GOC:dph] synonym: "patterning of blood vessels" BROAD [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: part_of GO:0048514 ! blood vessel morphogenesis relationship: part_of GO:0001525 ! angiogenesis [Term] id: GO:0001570 name: vasculogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." [PMID:8999798] synonym: "vascular morphogenesis" EXACT [] xref: Wikipedia:Vasculogenesis is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_formation_of UBERON:0001981 ! blood vessel relationship: part_of GO:0048514 ! blood vessel morphogenesis relationship: results_in_formation_of UBERON:0001981 ! blood vessel [Term] id: GO:0001578 name: microtubule bundle formation namespace: biological_process def: "A process that results in a parallel arrangement of microtubules." [GOC:dph] synonym: "microtubule bundling" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: has_participant GO:0005874 ! microtubule relationship: results_in_formation_of GO:0097427 ! microtubule bundle [Term] id: GO:0001654 name: eye development namespace: biological_process alt_id: GO:0042460 def: "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." [GOC:jid, GOC:jl] xref: Wikipedia:Eye_development is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000970 ! eye relationship: part_of GO:0150063 ! visual system development relationship: results_in_development_of UBERON:0000970 ! eye [Term] id: GO:0001655 name: urogenital system development namespace: biological_process def: "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004122 ! genitourinary system relationship: has_part GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0004122 ! genitourinary system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI [Term] id: GO:0001656 name: metanephros development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:bf, ISBN:0192800752] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000081 ! metanephros relationship: results_in_development_of UBERON:0000081 ! metanephros [Term] id: GO:0001657 name: ureteric bud development namespace: biological_process def: "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure." [GOC:go_curators] is_a: GO:0072164 ! mesonephric tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000084 ! ureteric bud relationship: results_in_development_of UBERON:0000084 ! ureteric bud [Term] id: GO:0001658 name: branching involved in ureteric bud morphogenesis namespace: biological_process def: "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, PMID:16916378] synonym: "ureteric bud branching" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: part_of GO:0060675 ! ureteric bud morphogenesis relationship: part_of GO:0060675 ! ureteric bud morphogenesis [Term] id: GO:0001659 name: temperature homeostasis namespace: biological_process def: "A homeostatic process in which an organism modulates its internal body temperature." [GOC:jl] synonym: "thermoregulation" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Thermoregulation is_a: GO:0048871 ! multicellular organismal-level homeostasis [Term] id: GO:0001667 name: ameboidal-type cell migration namespace: biological_process def: "Cell migration that is accomplished by extension and retraction of a pseudopodium." [GOC:dph] comment: Note that this term refers to a mode of migration rather than to any particular cell type. synonym: "ameboid cell migration" EXACT [] synonym: "amoeboid cell migration" EXACT [] synonym: "amoeboidal cell migration" EXACT [] is_a: GO:0016477 ! cell migration [Term] id: GO:0001669 name: acrosomal vesicle namespace: cellular_component def: "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." [ISBN:0124325653, ISBN:0198506732] synonym: "acrosomal granule" EXACT [GOC:sart] synonym: "acrosome" EXACT [GOC:dph] xref: Wikipedia:Acrosome is_a: GO:0030141 ! secretory granule relationship: part_of CL:0000019 ! sperm [Term] id: GO:0001673 name: male germ cell nucleus namespace: cellular_component alt_id: GO:0043081 def: "The nucleus of a male germ cell, a reproductive cell in males." [CL:0000015, GOC:hjd, GOC:mtg_sensu] synonym: "male germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000015 ! male germ cell relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: part_of CL:0000015 ! male germ cell [Term] id: GO:0001674 name: female germ cell nucleus namespace: cellular_component alt_id: GO:0043080 def: "The nucleus of the female germ cell, a reproductive cell in females." [CL:0000021, GOC:hjd] synonym: "female germ-cell nucleus" EXACT [] is_a: GO:0043073 ! germ cell nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000021 ! female germ cell relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: part_of CL:0000021 ! female germ cell [Term] id: GO:0001675 name: acrosome assembly namespace: biological_process def: "The formation of the acrosome from the spermatid Golgi." [GOC:dph, GOC:hjd, GOC:tb] synonym: "acrosome formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0033363 ! secretory granule organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0001669 ! acrosomal vesicle relationship: part_of GO:0007286 ! spermatid development relationship: results_in_assembly_of GO:0001669 ! acrosomal vesicle [Term] id: GO:0001677 name: formation of translation initiation ternary complex namespace: biological_process def: "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:hjd] synonym: "translation initiation ternary complex assembly" EXACT [] is_a: GO:0022618 ! protein-RNA complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0044207 ! translation initiation ternary complex relationship: part_of GO:0006413 ! translational initiation relationship: results_in_assembly_of GO:0044207 ! translation initiation ternary complex [Term] id: GO:0001696 name: gastric acid secretion namespace: biological_process def: "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:hjd] synonym: "hydrochloric acid secretion" NARROW [] is_a: GO:0022600 ! digestive system process is_a: GO:0046717 ! acid secretion [Term] id: GO:0001700 name: embryonic development via the syncytial blastoderm namespace: biological_process def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: in_taxon NCBITaxon:50557 {all_only="true"} ! Insecta relationship: only_in_taxon NCBITaxon:50557 ! Insecta [Term] id: GO:0001701 name: in utero embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0043009 ! chordate embryonic development relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria relationship: only_in_taxon NCBITaxon:32525 ! Theria [Term] id: GO:0001702 name: gastrulation with mouth forming second namespace: biological_process alt_id: GO:0010003 alt_id: GO:0048276 def: "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second." [GOC:go_curators, GOC:mtg_sensu] synonym: "deuterostomic gastrulation" EXACT [GOC:dph] is_a: GO:0007369 ! gastrulation relationship: in_taxon NCBITaxon:33511 {all_only="true"} ! Deuterostomia relationship: only_in_taxon NCBITaxon:33511 ! Deuterostomia [Term] id: GO:0001704 name: formation of primary germ layer namespace: biological_process def: "The formation of the ectoderm, mesoderm and endoderm during gastrulation." [GOC:go_curators] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000923 ! germ layer relationship: part_of GO:0007369 ! gastrulation relationship: results_in_formation_of UBERON:0000923 ! germ layer [Term] id: GO:0001705 name: ectoderm formation namespace: biological_process def: "The formation of ectoderm during gastrulation." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000924 ! ectoderm relationship: part_of GO:0007398 ! ectoderm development relationship: results_in_formation_of UBERON:0000924 ! ectoderm [Term] id: GO:0001706 name: endoderm formation namespace: biological_process def: "The formation of the endoderm during gastrulation." [GOC:go_curators] synonym: "endoblast formation" NARROW [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000925 ! endoderm relationship: part_of GO:0007492 ! endoderm development relationship: results_in_formation_of UBERON:0000925 ! endoderm [Term] id: GO:0001707 name: mesoderm formation namespace: biological_process def: "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:go_curators] is_a: GO:0001704 ! formation of primary germ layer intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000926 ! mesoderm relationship: part_of GO:0048332 ! mesoderm morphogenesis relationship: results_in_formation_of UBERON:0000926 ! mesoderm [Term] id: GO:0001743 name: lens placode formation namespace: biological_process def: "The initial developmental process that will lead to the formation of an eye." [GOC:dph] synonym: "optic placode formation" RELATED [] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003073 ! lens placode relationship: part_of GO:0048598 ! embryonic morphogenesis relationship: results_in_formation_of UBERON:0003073 ! lens placode [Term] id: GO:0001745 name: compound eye morphogenesis namespace: biological_process def: "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu] synonym: "insect-type retina morphogenesis" EXACT [PMID:11735386] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000018 ! compound eye relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048749 ! compound eye development relationship: results_in_morphogenesis_of UBERON:0000018 ! compound eye [Term] id: GO:0001751 name: compound eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." [GOC:go_curators] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000019 ! compound eye photoreceptor cell relationship: part_of GO:0001745 ! compound eye morphogenesis relationship: results_in_acquisition_of_features_of CL:2000019 ! compound eye photoreceptor cell [Term] id: GO:0001754 name: eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." [GOC:go_curators] is_a: GO:0046530 ! photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000287 ! eye photoreceptor cell relationship: part_of GO:0048592 ! eye morphogenesis relationship: results_in_acquisition_of_features_of CL:0000287 ! eye photoreceptor cell [Term] id: GO:0001755 name: neural crest cell migration namespace: biological_process def: "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." [GOC:ascb_2009, GOC:dph, GOC:tb, ISBN:0878932437] is_a: GO:0090497 ! mesenchymal cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000333 ! migratory neural crest cell relationship: part_of GO:0014032 ! neural crest cell development relationship: results_in_movement_of CL:0000333 ! migratory neural crest cell [Term] id: GO:0001756 name: somitogenesis namespace: biological_process def: "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [ISBN:0721662544] synonym: "formation of mesodermal clusters" EXACT systematic_synonym [] xref: Wikipedia:Somitogenesis is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0035282 ! segmentation is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002329 ! somite relationship: part_of GO:0043009 ! chordate embryonic development relationship: part_of GO:0061053 ! somite development relationship: results_in_formation_of UBERON:0002329 ! somite [Term] id: GO:0001763 name: morphogenesis of a branching structure namespace: biological_process def: "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." [ISBN:0721662544] synonym: "branching morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0001764 name: neuron migration namespace: biological_process def: "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." [CL:0000540, GOC:go_curators] synonym: "neuron chemotaxis" EXACT [] synonym: "neuron guidance" RELATED [] synonym: "neuronal migration" EXACT [] xref: Wikipedia:Neural_development#Neuron_migration xref: Wikipedia:Neuron_migration is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000540 ! neuron relationship: part_of GO:0048699 ! generation of neurons relationship: results_in_movement_of CL:0000540 ! neuron [Term] id: GO:0001767 name: establishment of lymphocyte polarity namespace: biological_process def: "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "lymphocyte polarization" EXACT [] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000542 ! lymphocyte relationship: occurs_in CL:0000542 ! lymphocyte relationship: part_of GO:0046649 ! lymphocyte activation [Term] id: GO:0001768 name: establishment of T cell polarity namespace: biological_process def: "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." [GOC:mgi_curators, PMID:11244041, PMID:12615889] synonym: "establishment of T lymphocyte polarity" EXACT [] synonym: "establishment of T-cell polarity" EXACT [] synonym: "establishment of T-lymphocyte polarity" EXACT [] synonym: "T cell polarization" EXACT [] synonym: "T lymphocyte polarization" EXACT [] synonym: "T-cell polarization" EXACT [] is_a: GO:0001767 ! establishment of lymphocyte polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000084 ! T cell relationship: occurs_in CL:0000084 ! T cell relationship: part_of GO:0042110 ! T cell activation [Term] id: GO:0001775 name: cell activation namespace: biological_process def: "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell." [GOC:mgi_curators] subset: goslim_pir is_a: GO:0009987 ! cellular process is_a: GO:0032501 ! multicellular organismal process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24416" xsd:anyURI [Term] id: GO:0001776 name: leukocyte homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, ISBN:0781735149] comment: Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus. synonym: "immune cell homeostasis" EXACT [] synonym: "leucocyte homeostasis" EXACT [] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000738 ! leukocyte relationship: acts_on_population_of CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0001777 name: T cell homeostatic proliferation namespace: biological_process def: "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." [GOC:mgi_curators, ISBN:0781735149] synonym: "resting T cell proliferation" EXACT [] synonym: "resting T-cell proliferation" EXACT [] synonym: "T lymphocyte homeostatic proliferation" EXACT [] synonym: "T-cell homeostatic proliferation" EXACT [] synonym: "T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000084 ! T cell intersection_of: part_of GO:0042592 ! homeostatic process relationship: part_of GO:0043029 ! T cell homeostasis [Term] id: GO:0001816 name: cytokine production namespace: biological_process alt_id: GO:0042032 alt_id: GO:0042089 alt_id: GO:0042107 alt_id: GO:0050663 def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate subset: goslim_pir synonym: "cytokine biosynthetic process" NARROW [] synonym: "cytokine metabolic process" NARROW [] synonym: "cytokine secretion" NARROW [] synonym: "interferon production" NARROW [GOC:add, GOC:mah] synonym: "interferon secretion" NARROW [GOC:add, GOC:mah] synonym: "interleukin production" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] synonym: "interleukin secretion" NARROW [GOC:add, GOC:mah, http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F] is_a: GO:0010467 ! gene expression is_a: GO:0032501 ! multicellular organismal process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19116" xsd:anyURI [Term] id: GO:0001817 name: regulation of cytokine production namespace: biological_process alt_id: GO:0042035 alt_id: GO:0050707 def: "Any process that modulates the frequency, rate, or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "regulation of cytokine anabolism" EXACT [] synonym: "regulation of cytokine biosynthesis" EXACT [] synonym: "regulation of cytokine biosynthetic process" NARROW [] synonym: "regulation of cytokine formation" EXACT [] synonym: "regulation of cytokine secretion" NARROW [] synonym: "regulation of cytokine synthesis" EXACT [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001816 ! cytokine production relationship: regulates GO:0001816 ! cytokine production [Term] id: GO:0001818 name: negative regulation of cytokine production namespace: biological_process alt_id: GO:0042036 alt_id: GO:0050710 def: "Any process that stops, prevents, or reduces the rate of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "down regulation of cytokine biosynthetic process" EXACT [] synonym: "down regulation of cytokine production" EXACT [] synonym: "down-regulation of cytokine biosynthetic process" EXACT [] synonym: "down-regulation of cytokine production" EXACT [] synonym: "downregulation of cytokine biosynthetic process" EXACT [] synonym: "downregulation of cytokine production" EXACT [] synonym: "inhibition of cytokine biosynthetic process" NARROW [] synonym: "inhibition of cytokine production" NARROW [] synonym: "negative regulation of cytokine anabolism" EXACT [] synonym: "negative regulation of cytokine biosynthesis" EXACT [] synonym: "negative regulation of cytokine biosynthetic process" NARROW [] synonym: "negative regulation of cytokine formation" EXACT [] synonym: "negative regulation of cytokine secretion" NARROW [] synonym: "negative regulation of cytokine synthesis" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001816 ! cytokine production relationship: negatively_regulates GO:0001816 ! cytokine production [Term] id: GO:0001819 name: positive regulation of cytokine production namespace: biological_process alt_id: GO:0042108 alt_id: GO:0050715 def: "Any process that activates or increases the frequency, rate or extent of production of a cytokine." [GOC:add, ISBN:0781735149] synonym: "activation of cytokine production" NARROW [] synonym: "positive regulation of cytokine biosynthetic process" NARROW [] synonym: "positive regulation of cytokine secretion" NARROW [] synonym: "stimulation of cytokine production" NARROW [] synonym: "up regulation of cytokine production" EXACT [] synonym: "up-regulation of cytokine production" EXACT [] synonym: "upregulation of cytokine production" EXACT [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001816 ! cytokine production relationship: positively_regulates GO:0001816 ! cytokine production [Term] id: GO:0001820 name: serotonin secretion namespace: biological_process def: "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." [GOC:ef, ISBN:0198506732, ISBN:0781735149] synonym: "5-HT secretion" EXACT [] synonym: "5-hydroxytryptamine secretion" EXACT [] synonym: "serotonin release" RELATED [GOC:tb] is_a: GO:0006837 ! serotonin transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0001822 name: kidney development namespace: biological_process def: "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10, ISBN:0124020607, ISBN:0721662544] synonym: "nephrogenesis" RELATED [GOC:rph] xref: Wikipedia:Kidney_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002113 ! kidney relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0002113 ! kidney [Term] id: GO:0001823 name: mesonephros development namespace: biological_process def: "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney." [GOC:dph, ISBN:0124020607, ISBN:0721662544, PMID:10535314] synonym: "Wolffian body development" EXACT [GOC:dph] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000080 ! mesonephros relationship: results_in_development_of UBERON:0000080 ! mesonephros [Term] id: GO:0001824 name: blastocyst development namespace: biological_process def: "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'. is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000358 ! blastocyst relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: part_of GO:0001701 ! in utero embryonic development relationship: results_in_development_of UBERON:0000358 ! blastocyst [Term] id: GO:0001825 name: blastocyst formation namespace: biological_process def: "The initial formation of a blastocyst from a solid ball of cells known as a morula." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'. is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000358 ! blastocyst relationship: part_of GO:0001824 ! blastocyst development relationship: results_in_formation_of UBERON:0000358 ! blastocyst [Term] id: GO:0001826 name: inner cell mass cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'. is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000020 ! inner cell mass cell relationship: part_of GO:0001825 ! blastocyst formation relationship: results_in_acquisition_of_features_of CL:2000020 ! inner cell mass cell [Term] id: GO:0001829 name: trophectodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'. synonym: "trophectoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000274 ! trophectodermal cell relationship: part_of GO:0001825 ! blastocyst formation relationship: results_in_acquisition_of_features_of CL:1000274 ! trophectodermal cell [Term] id: GO:0001831 name: trophectodermal cellular morphogenesis namespace: biological_process def: "The morphogenesis of trophectoderm cells." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. synonym: "trophectoderm cellular morphogenesis" EXACT [] is_a: GO:0000904 ! cell morphogenesis involved in differentiation is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:1000274 ! trophectodermal cell relationship: part_of GO:0001829 ! trophectodermal cell differentiation relationship: results_in_morphogenesis_of CL:1000274 ! trophectodermal cell [Term] id: GO:0001832 name: blastocyst growth namespace: biological_process def: "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'. is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of UBERON:0000358 ! blastocyst relationship: part_of GO:0001824 ! blastocyst development relationship: results_in_growth_of UBERON:0000358 ! blastocyst [Term] id: GO:0001833 name: inner cell mass cell proliferation namespace: biological_process def: "The proliferation of cells in the inner cell mass." [GOC:dph, GOC:isa_complete, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'. is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:2000020 ! inner cell mass cell relationship: acts_on_population_of CL:2000020 ! inner cell mass cell relationship: part_of GO:0001832 ! blastocyst growth [Term] id: GO:0001834 name: trophectodermal cell proliferation namespace: biological_process def: "The proliferation of cells in the trophectoderm." [GOC:dph, ISBN:0124020607, ISBN:0198542771] comment: See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. synonym: "trophectoderm cell proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:1000274 ! trophectodermal cell relationship: acts_on_population_of CL:1000274 ! trophectodermal cell relationship: part_of GO:0001832 ! blastocyst growth [Term] id: GO:0001837 name: epithelial to mesenchymal transition namespace: biological_process def: "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:dph, PMID:14701881] synonym: "EMT" EXACT [] synonym: "epithelial-mesenchymal transition" EXACT [] synonym: "mesenchymal cell differentiation from epithelial cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: has_input CL:0000066 ! epithelial cell intersection_of: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell relationship: has_input CL:0000066 ! epithelial cell [Term] id: GO:0001838 name: embryonic epithelial tube formation namespace: biological_process def: "The morphogenesis of an embryonic epithelium into a tube-shaped structure." [GOC:dph, ISBN:0824072820] is_a: GO:0072175 ! epithelial tube formation relationship: part_of GO:0016331 ! morphogenesis of embryonic epithelium [Term] id: GO:0001839 name: neural plate morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." [GOC:dph, ISBN:0878932437] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003075 ! neural plate relationship: part_of GO:0001840 ! neural plate development relationship: results_in_morphogenesis_of UBERON:0003075 ! neural plate [Term] id: GO:0001840 name: neural plate development namespace: biological_process def: "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GOC:dph, GOC:ef, ISBN:0878932437, ISBN:0878932585] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003075 ! neural plate relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_development_of UBERON:0003075 ! neural plate [Term] id: GO:0001841 name: neural tube formation namespace: biological_process alt_id: GO:0001679 def: "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GOC:dph, ISBN:0878932437] synonym: "neural tube morphogenesis" EXACT [GOC:dph] synonym: "neurulation" EXACT [] xref: Wikipedia:Neurulation is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001049 ! neural tube relationship: part_of GO:0021915 ! neural tube development relationship: results_in_formation_of UBERON:0001049 ! neural tube [Term] id: GO:0001842 name: neural fold formation namespace: biological_process def: "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." [GOC:dph, ISBN:0878932437] synonym: "neural groove formation" RELATED [GOC:dph] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005062 ! neural fold relationship: part_of GO:0014020 ! primary neural tube formation relationship: results_in_formation_of UBERON:0005062 ! neural fold [Term] id: GO:0001878 name: response to yeast namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species." [PMID:14707091] comment: defined as response to Saccharomycotina (true yeasts). This excludes fission yeast. is_a: GO:0009620 ! response to fungus intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input NCBITaxon:147537 ! Saccharomycotina relationship: has_input NCBITaxon:147537 ! Saccharomycotina [Term] id: GO:0001885 name: endothelial cell development namespace: biological_process def: "The progression of an endothelial cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000115 ! endothelial cell relationship: part_of GO:0045446 ! endothelial cell differentiation relationship: results_in_development_of CL:0000115 ! endothelial cell [Term] id: GO:0001886 name: endothelial cell morphogenesis namespace: biological_process def: "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000115 ! endothelial cell relationship: part_of GO:0001885 ! endothelial cell development relationship: results_in_morphogenesis_of CL:0000115 ! endothelial cell [Term] id: GO:0001889 name: liver development namespace: biological_process def: "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes." [GOC:add, ISBN:068340007X] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002107 ! liver relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: results_in_development_of UBERON:0002107 ! liver [Term] id: GO:0001890 name: placenta development namespace: biological_process def: "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "placental development" EXACT [] synonym: "placentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001987 ! placenta relationship: in_taxon NCBITaxon:32525 {all_only="true"} ! Theria relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: results_in_development_of UBERON:0001987 ! placenta [Term] id: GO:0001892 name: embryonic placenta development namespace: biological_process def: "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "fetal placenta development" EXACT [GOC:dph] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007106 ! chorionic villus relationship: part_of GO:0001701 ! in utero embryonic development relationship: part_of GO:0001890 ! placenta development relationship: results_in_development_of UBERON:0007106 ! chorionic villus [Term] id: GO:0001893 name: maternal placenta development namespace: biological_process def: "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." [GOC:add, ISBN:068340007X] synonym: "decidua development" RELATED [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development is_a: GO:0060135 ! maternal process involved in female pregnancy intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002450 ! decidua relationship: part_of GO:0001890 ! placenta development relationship: results_in_development_of UBERON:0002450 ! decidua [Term] id: GO:0001935 name: endothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [GOC:add, ISBN:0781735149] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000115 ! endothelial cell relationship: acts_on_population_of CL:0000115 ! endothelial cell [Term] id: GO:0001936 name: regulation of endothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." [GOC:add] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001935 ! endothelial cell proliferation relationship: regulates GO:0001935 ! endothelial cell proliferation [Term] id: GO:0001937 name: negative regulation of endothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "down regulation of endothelial cell proliferation" EXACT [] synonym: "down-regulation of endothelial cell proliferation" EXACT [] synonym: "downregulation of endothelial cell proliferation" EXACT [] synonym: "inhibition of endothelial cell proliferation" NARROW [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050680 ! negative regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001935 ! endothelial cell proliferation relationship: negatively_regulates GO:0001935 ! endothelial cell proliferation [Term] id: GO:0001938 name: positive regulation of endothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of endothelial cell proliferation." [GOC:add] synonym: "activation of endothelial cell proliferation" NARROW [] synonym: "stimulation of endothelial cell proliferation" NARROW [] synonym: "up regulation of endothelial cell proliferation" EXACT [] synonym: "up-regulation of endothelial cell proliferation" EXACT [] synonym: "upregulation of endothelial cell proliferation" EXACT [] is_a: GO:0001936 ! regulation of endothelial cell proliferation is_a: GO:0050679 ! positive regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001935 ! endothelial cell proliferation relationship: positively_regulates GO:0001935 ! endothelial cell proliferation [Term] id: GO:0001940 name: male pronucleus namespace: cellular_component def: "The pronucleus originating from the spermatozoa that was involved in fertilization." [GOC:hjd, ISBN:0198506732] is_a: GO:0045120 ! pronucleus [Term] id: GO:0001944 name: vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." [GOC:dph, UBERON:0002409] synonym: "vascular system development" RELATED [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002049 ! vasculature relationship: part_of GO:0072359 ! circulatory system development relationship: results_in_development_of UBERON:0002049 ! vasculature [Term] id: GO:0001955 name: blood vessel maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001981 ! blood vessel relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_maturation_of UBERON:0001981 ! blood vessel [Term] id: GO:0001956 name: positive regulation of neurotransmitter secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:hjd] synonym: "activation of neurotransmitter secretion" NARROW [] synonym: "stimulation of neurotransmitter secretion" NARROW [] synonym: "up regulation of neurotransmitter secretion" EXACT [] synonym: "up-regulation of neurotransmitter secretion" EXACT [] synonym: "upregulation of neurotransmitter secretion" EXACT [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:0051590 ! positive regulation of neurotransmitter transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007269 ! neurotransmitter secretion relationship: positively_regulates GO:0007269 ! neurotransmitter secretion [Term] id: GO:0001957 name: intramembranous ossification namespace: biological_process def: "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." [ISBN:0878932437] comment: An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division. synonym: "dermal ossification" NARROW [GO_REF:0000034] synonym: "intramembranous bone ossification" RELATED [GOC:cjm] xref: Wikipedia:Intramembranous_ossification is_a: GO:0036072 ! direct ossification [Term] id: GO:0002009 name: morphogenesis of an epithelium namespace: biological_process def: "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." [GOC:dph, GOC:jl, GOC:tb, ISBN:0198506732] synonym: "epithelium morphogenesis" EXACT [] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000483 ! epithelium relationship: part_of GO:0060429 ! epithelium development relationship: results_in_morphogenesis_of UBERON:0000483 ! epithelium [Term] id: GO:0002011 name: morphogenesis of an epithelial sheet namespace: biological_process def: "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0010136 ! epithelial sheet relationship: results_in_morphogenesis_of UBERON:0010136 ! epithelial sheet [Term] id: GO:0002027 name: regulation of heart rate namespace: biological_process def: "Any process that modulates the frequency or rate of heart contraction." [GOC:dph, GOC:tb, PMID:10358008] synonym: "cardiac chronotropy" EXACT [GOC:dph, GOC:tb] synonym: "regulation of heart contraction rate" EXACT [] synonym: "regulation of rate of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction [Term] id: GO:0002028 name: regulation of sodium ion transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph] synonym: "regulation of Na+ transport" EXACT [] synonym: "regulation of sodium transport" EXACT [] is_a: GO:0010959 ! regulation of metal ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006814 ! sodium ion transport relationship: regulates GO:0006814 ! sodium ion transport [Term] id: GO:0002052 name: positive regulation of neuroblast proliferation namespace: biological_process def: "Any process that activates or increases the rate of neuroblast proliferation." [GOC:dph] synonym: "activation of neuroblast proliferation" NARROW [] synonym: "stimulation of neuroblast proliferation" NARROW [] synonym: "up regulation of neuroblast proliferation" EXACT [] synonym: "up-regulation of neuroblast proliferation" EXACT [] synonym: "upregulation of neuroblast proliferation" EXACT [] is_a: GO:0050769 ! positive regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007405 ! neuroblast proliferation relationship: positively_regulates GO:0007405 ! neuroblast proliferation [Term] id: GO:0002053 name: positive regulation of mesenchymal cell proliferation namespace: biological_process def: "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." [GOC:dph] synonym: "activation of mesenchymal cell proliferation" NARROW [] synonym: "stimulation of mesenchymal cell proliferation" NARROW [] synonym: "up regulation of mesenchymal cell proliferation" EXACT [] synonym: "up-regulation of mesenchymal cell proliferation" EXACT [] synonym: "upregulation of mesenchymal cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010463 ! mesenchymal cell proliferation relationship: positively_regulates GO:0010463 ! mesenchymal cell proliferation [Term] id: GO:0002062 name: chondrocyte differentiation namespace: biological_process def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000138 ! chondrocyte relationship: part_of GO:0051216 ! cartilage development relationship: results_in_acquisition_of_features_of CL:0000138 ! chondrocyte [Term] id: GO:0002063 name: chondrocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000138 ! chondrocyte relationship: part_of GO:0002062 ! chondrocyte differentiation relationship: results_in_development_of CL:0000138 ! chondrocyte [Term] id: GO:0002064 name: epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000066 ! epithelial cell relationship: part_of GO:0030855 ! epithelial cell differentiation relationship: results_in_development_of CL:0000066 ! epithelial cell [Term] id: GO:0002065 name: columnar/cuboidal epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000075 ! columnar/cuboidal epithelial cell relationship: results_in_acquisition_of_features_of CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: GO:0002066 name: columnar/cuboidal epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002064 ! epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000075 ! columnar/cuboidal epithelial cell relationship: part_of GO:0002065 ! columnar/cuboidal epithelial cell differentiation relationship: results_in_development_of CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: GO:0002067 name: glandular epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell relationship: results_in_acquisition_of_features_of CL:0000150 ! glandular epithelial cell [Term] id: GO:0002068 name: glandular epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000150 ! glandular epithelial cell relationship: part_of GO:0002067 ! glandular epithelial cell differentiation relationship: results_in_development_of CL:0000150 ! glandular epithelial cell [Term] id: GO:0002069 name: columnar/cuboidal epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." [GOC:dph] is_a: GO:0002070 ! epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000075 ! columnar/cuboidal epithelial cell relationship: part_of GO:0002066 ! columnar/cuboidal epithelial cell development relationship: results_in_maturation_of CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: GO:0002070 name: epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." [GOC:dph] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000066 ! epithelial cell relationship: part_of GO:0002064 ! epithelial cell development relationship: results_in_maturation_of CL:0000066 ! epithelial cell [Term] id: GO:0002071 name: glandular epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." [GOC:dph] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000150 ! glandular epithelial cell relationship: part_of GO:0002068 ! glandular epithelial cell development relationship: results_in_maturation_of CL:0000150 ! glandular epithelial cell [Term] id: GO:0002072 name: optic cup morphogenesis involved in camera-type eye development namespace: biological_process def: "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb, ISBN:0878932437] synonym: "optic cup morphogenesis involved in camera-style eye development" EXACT [] is_a: GO:0016331 ! morphogenesis of embryonic epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003072 ! optic cup relationship: part_of GO:0060900 ! embryonic camera-type eye formation relationship: results_in_morphogenesis_of UBERON:0003072 ! optic cup [Term] id: GO:0002080 name: acrosomal membrane namespace: cellular_component def: "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." [GOC:dph] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0001669 ! acrosomal vesicle relationship: bounding_layer_of GO:0001669 ! acrosomal vesicle relationship: part_of GO:0001669 ! acrosomal vesicle [Term] id: GO:0002085 name: inhibition of neuroepithelial cell differentiation namespace: biological_process def: "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, PMID:16678814] synonym: "negative regulation of neural plate formation" NARROW [GOC:dph, GOC:tb] synonym: "repression of premature neural plate formation" NARROW [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0048505 ! regulation of timing of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation relationship: negatively_regulates GO:0060563 ! neuroepithelial cell differentiation [Term] id: GO:0002087 name: regulation of respiratory gaseous exchange by nervous system process namespace: biological_process def: "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." [GOC:dph, GOC:tb, PMID:12458206] synonym: "neurological control of breathing" EXACT [GOC:dph, GOC:tb] synonym: "regulation of respiratory gaseous exchange by neurological system process" EXACT [] is_a: GO:0044065 ! regulation of respiratory system process is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system [Term] id: GO:0002088 name: lens development in camera-type eye namespace: biological_process def: "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, ISBN:0582064333] synonym: "lens development" EXACT [] synonym: "lens development in camera-style eye" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000965 ! lens of camera-type eye relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_development_of UBERON:0000965 ! lens of camera-type eye [Term] id: GO:0002089 name: lens morphogenesis in camera-type eye namespace: biological_process def: "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." [GOC:dph, GOC:mtg_sensu] synonym: "lens morphogenesis" EXACT [] synonym: "lens morphogenesis in camera-style eye" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000965 ! lens of camera-type eye relationship: part_of GO:0002088 ! lens development in camera-type eye relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0000965 ! lens of camera-type eye [Term] id: GO:0002119 name: nematode larval development namespace: biological_process def: "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:ems, GOC:kmv] is_a: GO:0002164 ! larval development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009850 ! nematode larva relationship: in_taxon NCBITaxon:33213 {all_only="true"} ! Bilateria relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: results_in_development_of UBERON:0009850 ! nematode larva [Term] id: GO:0002164 name: larval development namespace: biological_process def: "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." [GOC:jid, ISBN:0877795088] is_a: GO:0007275 ! multicellular organism development is_a: GO:0009791 ! post-embryonic development [Term] id: GO:0002176 name: male germ cell proliferation namespace: biological_process def: "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population." [GOC:hjd] is_a: GO:0036093 ! germ cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000015 ! male germ cell relationship: acts_on_population_of CL:0000015 ! male germ cell created_by: hjd creation_date: 2010-11-18T02:35:14Z [Term] id: GO:0002213 name: defense response to insect namespace: biological_process alt_id: GO:0002214 def: "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." [GOC:add] synonym: "physiological defense response to insect" EXACT [] is_a: GO:0006952 ! defense response intersection_of: GO:0006952 ! defense response intersection_of: has_input NCBITaxon:50557 ! Insecta relationship: has_input NCBITaxon:50557 ! Insecta [Term] id: GO:0002215 name: defense response to nematode namespace: biological_process alt_id: GO:0002216 def: "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:add, PMID:11516579, PMID:14506883] synonym: "physiological defense response to nematode" EXACT [] is_a: GO:0006952 ! defense response intersection_of: GO:0006952 ! defense response intersection_of: has_input NCBITaxon:6231 ! Nematoda relationship: has_input NCBITaxon:6231 ! Nematoda [Term] id: GO:0002244 name: hematopoietic progenitor cell differentiation namespace: biological_process def: "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." [GOC:add, GOC:rl, ISBN:0781735149, PMID:16551251] synonym: "haematopoietic progenitor cell differentiation" EXACT [] synonym: "haemopoietic progenitor cell differentiation" EXACT [] synonym: "hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008001 ! hematopoietic precursor cell relationship: part_of GO:0030097 ! hemopoiesis relationship: results_in_acquisition_of_features_of CL:0008001 ! hematopoietic precursor cell [Term] id: GO:0002250 name: adaptive immune response namespace: biological_process def: "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "acquired immune response" EXACT [ISBN:068340007X] synonym: "immune memory response" EXACT [GOC:add] xref: Wikipedia:Adaptive_immune_system is_a: GO:0006955 ! immune response relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0002251 name: organ or tissue specific immune response namespace: biological_process def: "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." [GO_REF:0000022, GOC:jal] synonym: "immune response in organ or tissue" EXACT [] is_a: GO:0006955 ! immune response [Term] id: GO:0002252 name: immune effector process namespace: biological_process def: "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation." [GO_REF:0000022, GOC:add, ISBN:0781735149] is_a: GO:0002376 ! immune system process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18737" xsd:anyURI [Term] id: GO:0002260 name: lymphocyte homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:add, PMID:15826826, PMID:16319493, PMID:16551252, PMID:16551262] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000542 ! lymphocyte relationship: acts_on_population_of CL:0000542 ! lymphocyte [Term] id: GO:0002262 name: myeloid cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000763, GOC:add] is_a: GO:0002376 ! immune system process is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000763 ! myeloid cell relationship: acts_on_population_of CL:0000763 ! myeloid cell [Term] id: GO:0002263 name: cell activation involved in immune response namespace: biological_process def: "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell activation during immune response" RELATED [GOC:tb] is_a: GO:0001775 ! cell activation is_a: GO:0002252 ! immune effector process intersection_of: GO:0001775 ! cell activation intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002264 name: endothelial cell activation involved in immune response namespace: biological_process def: "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "endothelial cell activation during immune response" RELATED [GOC:tb] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0042118 ! endothelial cell activation intersection_of: GO:0042118 ! endothelial cell activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002269 name: leukocyte activation involved in inflammatory response namespace: biological_process def: "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." [GOC:add, ISBN:0781735149] synonym: "immune cell activation during inflammatory response" RELATED [] synonym: "leukocyte activation during inflammatory response" RELATED [GOC:tb] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002274 name: myeloid leukocyte activation namespace: biological_process def: "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte activation" EXACT [] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000766 ! myeloid leukocyte relationship: has_input CL:0000766 ! myeloid leukocyte [Term] id: GO:0002285 name: lymphocyte activation involved in immune response namespace: biological_process def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "lymphocyte activation during immune response" RELATED [GOC:tb] is_a: GO:0002366 ! leukocyte activation involved in immune response is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0046649 ! lymphocyte activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002286 name: T cell activation involved in immune response namespace: biological_process def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "T cell activation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte activation during immune response" RELATED [] synonym: "T-cell activation during immune response" RELATED [] synonym: "T-lymphocyte activation during immune response" RELATED [] is_a: GO:0002285 ! lymphocyte activation involved in immune response is_a: GO:0042110 ! T cell activation intersection_of: GO:0042110 ! T cell activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002292 name: T cell differentiation involved in immune response namespace: biological_process def: "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." [GOC:add, ISBN:0781735149] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "T cell development involved in immune response" RELATED [GOC:add] synonym: "T cell differentiation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte differentiation during immune response" RELATED [] synonym: "T-cell differentiation during immune response" RELATED [] synonym: "T-lymphocyte differentiation during immune response" RELATED [] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0030217 ! T cell differentiation intersection_of: GO:0030217 ! T cell differentiation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002309 name: T cell proliferation involved in immune response namespace: biological_process def: "The expansion of a T cell population by cell division as part of an immune response." [GOC:add, ISBN:0781735149] synonym: "T cell proliferation during immune response" RELATED [GOC:tb] synonym: "T lymphocyte proliferation during immune response" RELATED [] synonym: "T-cell proliferation during immune response" RELATED [] synonym: "T-lymphocyte proliferation during immune response" RELATED [] is_a: GO:0002286 ! T cell activation involved in immune response is_a: GO:0042098 ! T cell proliferation intersection_of: GO:0042098 ! T cell proliferation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002318 name: myeloid progenitor cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." [GOC:add, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000839 ! myeloid lineage restricted progenitor cell relationship: results_in_acquisition_of_features_of CL:0000839 ! myeloid lineage restricted progenitor cell [Term] id: GO:0002320 name: lymphoid progenitor cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." [GOC:add, PMID:16551251, PMID:16551264] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000838 ! lymphoid lineage restricted progenitor cell relationship: results_in_acquisition_of_features_of CL:0000838 ! lymphoid lineage restricted progenitor cell [Term] id: GO:0002351 name: serotonin production involved in inflammatory response namespace: biological_process def: "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149, PMID:16730260] synonym: "serotonin production involved in acute inflammatory response" BROAD [] is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response [Term] id: GO:0002366 name: leukocyte activation involved in immune response namespace: biological_process def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." [GOC:add, ISBN:0781735149] synonym: "immune cell activation during immune response" RELATED [] synonym: "leucocyte activation during immune response" RELATED [] synonym: "leukocyte activation during immune response" RELATED [GOC:tb] is_a: GO:0002263 ! cell activation involved in immune response is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0045321 ! leukocyte activation intersection_of: part_of GO:0006955 ! immune response [Term] id: GO:0002367 name: cytokine production involved in immune response namespace: biological_process alt_id: GO:0002374 alt_id: GO:0002375 def: "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "cytokine biosynthetic process involved in immune response" NARROW [] synonym: "cytokine production during immune response" RELATED [GOC:dph] synonym: "cytokine secretion during immune response" RELATED [GOC:dph] synonym: "cytokine secretion involved in immune response" RELATED [] is_a: GO:0001816 ! cytokine production is_a: GO:0002440 ! production of molecular mediator of immune response intersection_of: GO:0001816 ! cytokine production intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002369 name: T cell cytokine production namespace: biological_process def: "Any process that contributes to cytokine production by a T cell." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "T lymphocyte cytokine production" EXACT [] synonym: "T-cell cytokine production" EXACT [] synonym: "T-lymphocyte cytokine production" EXACT [] is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002456 ! T cell mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: process_has_causal_agent CL:0000084 ! T cell [Term] id: GO:0002371 name: dendritic cell cytokine production namespace: biological_process def: "Any process that contributes to cytokine production by a dendritic cell." [GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate is_a: GO:0002367 ! cytokine production involved in immune response is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0001816 ! cytokine production intersection_of: process_has_causal_agent CL:0000451 ! dendritic cell relationship: process_has_causal_agent CL:0000451 ! dendritic cell [Term] id: GO:0002376 name: immune system process namespace: biological_process def: "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." [GO_REF:0000022, GOC:add] comment: Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501). subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir xref: Wikipedia:Immune_system is_a: GO:0008150 ! biological_process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0002384 name: hepatic immune response namespace: biological_process def: "An immune response taking place in the liver." [GO_REF:0000022, GOC:jal, ISBN:0781735149] is_a: GO:0002251 ! organ or tissue specific immune response intersection_of: GO:0006955 ! immune response intersection_of: occurs_in UBERON:0002107 ! liver relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in UBERON:0002107 ! liver relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0002396 name: MHC protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] is_a: GO:0065003 ! protein-containing complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0042611 ! MHC protein complex relationship: results_in_assembly_of GO:0042611 ! MHC protein complex [Term] id: GO:0002399 name: MHC class II protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0002396 ! MHC protein complex assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0042613 ! MHC class II protein complex relationship: results_in_assembly_of GO:0042613 ! MHC class II protein complex [Term] id: GO:0002440 name: production of molecular mediator of immune response namespace: biological_process def: "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." [GO_REF:0000022, GOC:add, ISBN:0781735149] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. subset: gocheck_do_not_annotate synonym: "production of cellular mediator of immune response" RELATED [] is_a: GO:0002376 ! immune system process is_a: GO:0010467 ! gene expression [Term] id: GO:0002442 name: serotonin secretion involved in inflammatory response namespace: biological_process def: "The regulated release of serotonin by a cell as part of an inflammatory response." [GOC:add, ISBN:0781735149] synonym: "serotonin release involved in inflammatory response" RELATED [GOC:tb] synonym: "serotonin secretion involved in acute inflammatory response" BROAD [] is_a: GO:0001820 ! serotonin secretion intersection_of: GO:0001820 ! serotonin secretion intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0002351 ! serotonin production involved in inflammatory response [Term] id: GO:0002443 name: leukocyte mediated immunity namespace: biological_process alt_id: GO:0019723 alt_id: GO:0042087 def: "Any process involved in the carrying out of an immune response by a leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immune response" RELATED [] synonym: "cellular immune response" RELATED [] synonym: "immune cell effector process" EXACT [] synonym: "immune cell mediated immunity" EXACT [] synonym: "leucocyte immune effector process" EXACT [] synonym: "leucocyte mediated immunity" EXACT [] synonym: "leukocyte immune effector process" EXACT [] is_a: GO:0002252 ! immune effector process intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: process_has_causal_agent CL:0000738 ! leukocyte [Term] id: GO:0002444 name: myeloid leukocyte mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a myeloid leukocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "myeloid leucocyte immune effector process" EXACT [] synonym: "myeloid leucocyte mediated immunity" EXACT [] synonym: "myeloid leukocyte immune effector process" EXACT [] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000766 ! myeloid leukocyte relationship: process_has_causal_agent CL:0000766 ! myeloid leukocyte [Term] id: GO:0002449 name: lymphocyte mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a lymphocyte." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immunity" BROAD [] synonym: "cellular immune response" BROAD [] is_a: GO:0002443 ! leukocyte mediated immunity intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000542 ! lymphocyte relationship: process_has_causal_agent CL:0000542 ! lymphocyte [Term] id: GO:0002456 name: T cell mediated immunity namespace: biological_process def: "Any process involved in the carrying out of an immune response by a T cell." [GO_REF:0000022, GOC:add, ISBN:0781735149] synonym: "cell-mediated immunity" BROAD [] synonym: "cellular immune response" BROAD [] synonym: "T lymphocyte mediated immunity" EXACT [] synonym: "T-cell mediated immunity" EXACT [] synonym: "T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002449 ! lymphocyte mediated immunity is_a: GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0002376 ! immune system process intersection_of: process_has_causal_agent CL:0000084 ! T cell relationship: process_has_causal_agent CL:0000084 ! T cell [Term] id: GO:0002457 name: T cell antigen processing and presentation namespace: biological_process def: "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, PMID:11417857, PMID:15120183] synonym: "T lymphocyte antigen processing and presentation" EXACT [] synonym: "T-cell antigen processing and presentation" EXACT [] synonym: "T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: occurs_in CL:0000084 ! T cell relationship: occurs_in CL:0000084 ! T cell relationship: part_of GO:0002456 ! T cell mediated immunity [Term] id: GO:0002460 name: adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." [GOC:add, GOC:mtg_sensu, ISBN:0781735149, ISBN:1405196831] is_a: GO:0002250 ! adaptive immune response [Term] id: GO:0002468 name: dendritic cell antigen processing and presentation namespace: biological_process def: "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GOC:add, ISBN:0781735149, PMID:15771591] is_a: GO:0019882 ! antigen processing and presentation intersection_of: GO:0019882 ! antigen processing and presentation intersection_of: occurs_in CL:0000451 ! dendritic cell relationship: occurs_in CL:0000451 ! dendritic cell [Term] id: GO:0002504 name: antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." [GOC:add, ISBN:0781735149, PMID:15531770, PMID:15771591, PMID:16153240] synonym: "peptide or polysaccharide antigen processing and presentation of via MHC class II" EXACT [] is_a: GO:0019882 ! antigen processing and presentation [Term] id: GO:0002520 name: immune system development namespace: biological_process def: "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:add, GOC:dph] subset: goslim_drosophila is_a: GO:0002376 ! immune system process is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002405 ! immune system relationship: results_in_development_of UBERON:0002405 ! immune system [Term] id: GO:0002521 name: leukocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:add, PMID:16551264] synonym: "immune cell differentiation" EXACT [] synonym: "leucocyte differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000738 ! leukocyte relationship: part_of GO:0030097 ! hemopoiesis relationship: results_in_acquisition_of_features_of CL:0000738 ! leukocyte [Term] id: GO:0002522 name: leukocyte migration involved in immune response namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration during immune response" EXACT [] synonym: "immune cell trafficking during immune response" EXACT [] synonym: "leucocyte migration during immune response" EXACT [] synonym: "leucocyte trafficking during immune response" EXACT [] synonym: "leukocyte trafficking during immune response" EXACT [] is_a: GO:0002252 ! immune effector process is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: part_of GO:0006955 ! immune response relationship: part_of GO:0006955 ! immune response [Term] id: GO:0002523 name: leukocyte migration involved in inflammatory response namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration during inflammatory response" RELATED [] synonym: "immune cell trafficking during inflammatory response" RELATED [] synonym: "leucocyte migration during inflammatory response" RELATED [] synonym: "leucocyte trafficking during inflammatory response" RELATED [] synonym: "leukocyte migration during inflammatory response" RELATED [GOC:dph] synonym: "leukocyte trafficking during inflammatory response" RELATED [] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0050900 ! leukocyte migration intersection_of: part_of GO:0006954 ! inflammatory response relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002532 name: production of molecular mediator involved in inflammatory response namespace: biological_process def: "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." [GOC:add, GOC:dph, GOC:tb, ISBN:0781735149] synonym: "production of cellular mediator of acute inflammation" RELATED [] synonym: "production of molecular mediator involved in acute inflammatory response" BROAD [] is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002534 name: cytokine production involved in inflammatory response namespace: biological_process def: "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." [GOC:add, ISBN:0781735149] subset: gocheck_do_not_annotate synonym: "cytokine production involved in acute inflammatory response" BROAD [] is_a: GO:0001816 ! cytokine production is_a: GO:0002532 ! production of molecular mediator involved in inflammatory response intersection_of: GO:0001816 ! cytokine production intersection_of: part_of GO:0006954 ! inflammatory response [Term] id: GO:0002572 name: pro-T cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." [GOC:add, ISBN:0781735149] synonym: "pro-T lymphocyte differentiation" EXACT [] is_a: GO:0002320 ! lymphoid progenitor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000827 ! pro-T cell relationship: part_of GO:0030217 ! T cell differentiation relationship: results_in_acquisition_of_features_of CL:0000827 ! pro-T cell [Term] id: GO:0002573 name: myeloid leukocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." [GOC:add, PMID:16551251] synonym: "myeloid leucocyte differentiation" EXACT [] is_a: GO:0002521 ! leukocyte differentiation is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000766 ! myeloid leukocyte relationship: results_in_acquisition_of_features_of CL:0000766 ! myeloid leukocyte [Term] id: GO:0002577 name: regulation of antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019882 ! antigen processing and presentation relationship: regulates GO:0019882 ! antigen processing and presentation [Term] id: GO:0002578 name: negative regulation of antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "down regulation of antigen processing and presentation" EXACT [] synonym: "down-regulation of antigen processing and presentation" EXACT [] synonym: "downregulation of antigen processing and presentation" EXACT [] synonym: "inhibition of antigen processing and presentation" NARROW [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002683 ! negative regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019882 ! antigen processing and presentation relationship: negatively_regulates GO:0019882 ! antigen processing and presentation [Term] id: GO:0002579 name: positive regulation of antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." [GOC:add] synonym: "activation of antigen processing and presentation" NARROW [] synonym: "stimulation of antigen processing and presentation" NARROW [] synonym: "up regulation of antigen processing and presentation" EXACT [] synonym: "up-regulation of antigen processing and presentation" EXACT [] synonym: "upregulation of antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002684 ! positive regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019882 ! antigen processing and presentation relationship: positively_regulates GO:0019882 ! antigen processing and presentation [Term] id: GO:0002580 name: regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002581 name: negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: negatively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002582 name: positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." [GOC:add] synonym: "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" EXACT [] synonym: "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" NARROW [] synonym: "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] synonym: "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002580 ! regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II relationship: positively_regulates GO:0002504 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II [Term] id: GO:0002604 name: regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] is_a: GO:0002577 ! regulation of antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002468 ! dendritic cell antigen processing and presentation relationship: regulates GO:0002468 ! dendritic cell antigen processing and presentation [Term] id: GO:0002605 name: negative regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "down regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "down-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "downregulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "inhibition of dendritic cell antigen processing and presentation" NARROW [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation relationship: negatively_regulates GO:0002468 ! dendritic cell antigen processing and presentation [Term] id: GO:0002606 name: positive regulation of dendritic cell antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." [GOC:add] synonym: "activation of dendritic cell antigen processing and presentation" NARROW [] synonym: "stimulation of dendritic cell antigen processing and presentation" NARROW [] synonym: "up regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "up-regulation of dendritic cell antigen processing and presentation" EXACT [] synonym: "upregulation of dendritic cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002604 ! regulation of dendritic cell antigen processing and presentation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation relationship: positively_regulates GO:0002468 ! dendritic cell antigen processing and presentation [Term] id: GO:0002625 name: regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "regulation of T-cell antigen processing and presentation" EXACT [] synonym: "regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002577 ! regulation of antigen processing and presentation is_a: GO:0002709 ! regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002457 ! T cell antigen processing and presentation relationship: regulates GO:0002457 ! T cell antigen processing and presentation [Term] id: GO:0002626 name: negative regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "down regulation of T cell antigen processing and presentation" EXACT [] synonym: "down-regulation of T cell antigen processing and presentation" EXACT [] synonym: "downregulation of T cell antigen processing and presentation" EXACT [] synonym: "inhibition of T cell antigen processing and presentation" NARROW [] synonym: "negative regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "negative regulation of T-cell antigen processing and presentation" EXACT [] synonym: "negative regulation of T-lymphocyte antigen processing and presentation" EXACT [] is_a: GO:0002578 ! negative regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002710 ! negative regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002457 ! T cell antigen processing and presentation relationship: negatively_regulates GO:0002457 ! T cell antigen processing and presentation [Term] id: GO:0002627 name: positive regulation of T cell antigen processing and presentation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." [GOC:add] synonym: "activation of T cell antigen processing and presentation" NARROW [] synonym: "positive regulation of T lymphocyte antigen processing and presentation" EXACT [] synonym: "positive regulation of T-cell antigen processing and presentation" EXACT [] synonym: "positive regulation of T-lymphocyte antigen processing and presentation" EXACT [] synonym: "stimulation of T cell antigen processing and presentation" NARROW [] synonym: "up regulation of T cell antigen processing and presentation" EXACT [] synonym: "up-regulation of T cell antigen processing and presentation" EXACT [] synonym: "upregulation of T cell antigen processing and presentation" EXACT [] is_a: GO:0002579 ! positive regulation of antigen processing and presentation is_a: GO:0002625 ! regulation of T cell antigen processing and presentation is_a: GO:0002711 ! positive regulation of T cell mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002457 ! T cell antigen processing and presentation relationship: positively_regulates GO:0002457 ! T cell antigen processing and presentation [Term] id: GO:0002682 name: regulation of immune system process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an immune system process." [GOC:add] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002376 ! immune system process relationship: regulates GO:0002376 ! immune system process [Term] id: GO:0002683 name: negative regulation of immune system process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "down regulation of immune system process" EXACT [] synonym: "down-regulation of immune system process" EXACT [] synonym: "downregulation of immune system process" EXACT [] synonym: "inhibition of immune system process" NARROW [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002376 ! immune system process relationship: negatively_regulates GO:0002376 ! immune system process [Term] id: GO:0002684 name: positive regulation of immune system process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an immune system process." [GOC:add] synonym: "activation of immune system process" NARROW [] synonym: "stimulation of immune system process" NARROW [] synonym: "up regulation of immune system process" EXACT [] synonym: "up-regulation of immune system process" EXACT [] synonym: "upregulation of immune system process" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002376 ! immune system process relationship: positively_regulates GO:0002376 ! immune system process [Term] id: GO:0002685 name: regulation of leukocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "regulation of immune cell migration" EXACT [] synonym: "regulation of leucocyte migration" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050900 ! leukocyte migration relationship: regulates GO:0050900 ! leukocyte migration [Term] id: GO:0002686 name: negative regulation of leukocyte migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "down regulation of leukocyte migration" EXACT [] synonym: "down-regulation of leukocyte migration" EXACT [] synonym: "downregulation of leukocyte migration" EXACT [] synonym: "inhibition of leukocyte migration" NARROW [] synonym: "negative regulation of immune cell migration" EXACT [] synonym: "negative regulation of leucocyte migration" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050900 ! leukocyte migration relationship: negatively_regulates GO:0050900 ! leukocyte migration [Term] id: GO:0002687 name: positive regulation of leukocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." [GOC:add] synonym: "activation of leukocyte migration" NARROW [] synonym: "positive regulation of immune cell migration" EXACT [] synonym: "positive regulation of leucocyte migration" EXACT [] synonym: "stimulation of leukocyte migration" NARROW [] synonym: "up regulation of leukocyte migration" EXACT [] synonym: "up-regulation of leukocyte migration" EXACT [] synonym: "upregulation of leukocyte migration" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002685 ! regulation of leukocyte migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050900 ! leukocyte migration relationship: positively_regulates GO:0050900 ! leukocyte migration [Term] id: GO:0002694 name: regulation of leukocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "regulation of immune cell activation" EXACT [] synonym: "regulation of leucocyte activation" EXACT [] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045321 ! leukocyte activation relationship: regulates GO:0045321 ! leukocyte activation [Term] id: GO:0002695 name: negative regulation of leukocyte activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "down regulation of leukocyte activation" EXACT [] synonym: "down-regulation of leukocyte activation" EXACT [] synonym: "downregulation of leukocyte activation" EXACT [] synonym: "inhibition of leukocyte activation" NARROW [] synonym: "negative regulation of immune cell activation" EXACT [] synonym: "negative regulation of leucocyte activation" EXACT [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050866 ! negative regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045321 ! leukocyte activation relationship: negatively_regulates GO:0045321 ! leukocyte activation [Term] id: GO:0002696 name: positive regulation of leukocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." [GOC:add] synonym: "activation of leukocyte activation" NARROW [] synonym: "positive regulation of immune cell activation" EXACT [] synonym: "positive regulation of leucocyte activation" EXACT [] synonym: "stimulation of leukocyte activation" NARROW [] synonym: "up regulation of leukocyte activation" EXACT [] synonym: "up-regulation of leukocyte activation" EXACT [] synonym: "upregulation of leukocyte activation" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002694 ! regulation of leukocyte activation is_a: GO:0050867 ! positive regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045321 ! leukocyte activation relationship: positively_regulates GO:0045321 ! leukocyte activation [Term] id: GO:0002697 name: regulation of immune effector process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an immune effector process." [GOC:add] is_a: GO:0002682 ! regulation of immune system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002252 ! immune effector process relationship: regulates GO:0002252 ! immune effector process [Term] id: GO:0002698 name: negative regulation of immune effector process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "down regulation of immune effector process" EXACT [] synonym: "down-regulation of immune effector process" EXACT [] synonym: "downregulation of immune effector process" EXACT [] synonym: "inhibition of immune effector process" NARROW [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002252 ! immune effector process relationship: negatively_regulates GO:0002252 ! immune effector process [Term] id: GO:0002699 name: positive regulation of immune effector process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an immune effector process." [GOC:add] synonym: "activation of immune effector process" NARROW [] synonym: "stimulation of immune effector process" NARROW [] synonym: "up regulation of immune effector process" EXACT [] synonym: "up-regulation of immune effector process" EXACT [] synonym: "upregulation of immune effector process" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002252 ! immune effector process relationship: positively_regulates GO:0002252 ! immune effector process [Term] id: GO:0002700 name: regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] is_a: GO:0002697 ! regulation of immune effector process is_a: GO:0010468 ! regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002440 ! production of molecular mediator of immune response relationship: regulates GO:0002440 ! production of molecular mediator of immune response [Term] id: GO:0002701 name: negative regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "down regulation of production of molecular mediator of immune response" EXACT [] synonym: "down-regulation of production of molecular mediator of immune response" EXACT [] synonym: "downregulation of production of molecular mediator of immune response" EXACT [] synonym: "inhibition of production of molecular mediator of immune response" NARROW [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010629 ! negative regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002440 ! production of molecular mediator of immune response relationship: negatively_regulates GO:0002440 ! production of molecular mediator of immune response [Term] id: GO:0002702 name: positive regulation of production of molecular mediator of immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." [GOC:add] synonym: "activation of production of molecular mediator of immune response" NARROW [] synonym: "stimulation of production of molecular mediator of immune response" NARROW [] synonym: "up regulation of production of molecular mediator of immune response" EXACT [] synonym: "up-regulation of production of molecular mediator of immune response" EXACT [] synonym: "upregulation of production of molecular mediator of immune response" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002700 ! regulation of production of molecular mediator of immune response is_a: GO:0010628 ! positive regulation of gene expression intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002440 ! production of molecular mediator of immune response relationship: positively_regulates GO:0002440 ! production of molecular mediator of immune response [Term] id: GO:0002703 name: regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "regulation of immune cell mediated immunity" EXACT [] synonym: "regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002697 ! regulation of immune effector process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002443 ! leukocyte mediated immunity relationship: regulates GO:0002443 ! leukocyte mediated immunity [Term] id: GO:0002704 name: negative regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "down regulation of leukocyte mediated immunity" EXACT [] synonym: "down-regulation of leukocyte mediated immunity" EXACT [] synonym: "downregulation of leukocyte mediated immunity" EXACT [] synonym: "inhibition of leukocyte mediated immunity" NARROW [] synonym: "negative regulation of immune cell mediated immunity" EXACT [] synonym: "negative regulation of leucocyte mediated immunity" EXACT [] is_a: GO:0002698 ! negative regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002443 ! leukocyte mediated immunity relationship: negatively_regulates GO:0002443 ! leukocyte mediated immunity [Term] id: GO:0002705 name: positive regulation of leukocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." [GOC:add] synonym: "activation of leukocyte mediated immunity" NARROW [] synonym: "positive regulation of immune cell mediated immunity" EXACT [] synonym: "positive regulation of leucocyte mediated immunity" EXACT [] synonym: "stimulation of leukocyte mediated immunity" NARROW [] synonym: "up regulation of leukocyte mediated immunity" EXACT [] synonym: "up-regulation of leukocyte mediated immunity" EXACT [] synonym: "upregulation of leukocyte mediated immunity" EXACT [] is_a: GO:0002699 ! positive regulation of immune effector process is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002443 ! leukocyte mediated immunity relationship: positively_regulates GO:0002443 ! leukocyte mediated immunity [Term] id: GO:0002706 name: regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002449 ! lymphocyte mediated immunity relationship: regulates GO:0002449 ! lymphocyte mediated immunity [Term] id: GO:0002707 name: negative regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "down regulation of lymphocyte mediated immunity" EXACT [] synonym: "down-regulation of lymphocyte mediated immunity" EXACT [] synonym: "downregulation of lymphocyte mediated immunity" EXACT [] synonym: "inhibition of lymphocyte mediated immunity" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002449 ! lymphocyte mediated immunity relationship: negatively_regulates GO:0002449 ! lymphocyte mediated immunity [Term] id: GO:0002708 name: positive regulation of lymphocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." [GOC:add] synonym: "activation of lymphocyte mediated immunity" NARROW [] synonym: "stimulation of lymphocyte mediated immunity" NARROW [] synonym: "up regulation of lymphocyte mediated immunity" EXACT [] synonym: "up-regulation of lymphocyte mediated immunity" EXACT [] synonym: "upregulation of lymphocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002706 ! regulation of lymphocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002449 ! lymphocyte mediated immunity relationship: positively_regulates GO:0002449 ! lymphocyte mediated immunity [Term] id: GO:0002709 name: regulation of T cell mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "regulation of T lymphocyte mediated immunity" EXACT [] synonym: "regulation of T-cell mediated immunity" EXACT [] synonym: "regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002706 ! regulation of lymphocyte mediated immunity is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002456 ! T cell mediated immunity relationship: regulates GO:0002456 ! T cell mediated immunity [Term] id: GO:0002710 name: negative regulation of T cell mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "down regulation of T cell mediated immunity" EXACT [] synonym: "down-regulation of T cell mediated immunity" EXACT [] synonym: "downregulation of T cell mediated immunity" EXACT [] synonym: "inhibition of T cell mediated immunity" NARROW [] synonym: "negative regulation of T lymphocyte mediated immunity" EXACT [] synonym: "negative regulation of T-cell mediated immunity" EXACT [] synonym: "negative regulation of T-lymphocyte mediated immunity" EXACT [] is_a: GO:0002707 ! negative regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002823 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002456 ! T cell mediated immunity relationship: negatively_regulates GO:0002456 ! T cell mediated immunity [Term] id: GO:0002711 name: positive regulation of T cell mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." [GOC:add] synonym: "activation of T cell mediated immunity" NARROW [] synonym: "positive regulation of T lymphocyte mediated immunity" EXACT [] synonym: "positive regulation of T-cell mediated immunity" EXACT [] synonym: "positive regulation of T-lymphocyte mediated immunity" EXACT [] synonym: "stimulation of T cell mediated immunity" NARROW [] synonym: "up regulation of T cell mediated immunity" EXACT [] synonym: "up-regulation of T cell mediated immunity" EXACT [] synonym: "upregulation of T cell mediated immunity" EXACT [] is_a: GO:0002708 ! positive regulation of lymphocyte mediated immunity is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002824 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002456 ! T cell mediated immunity relationship: positively_regulates GO:0002456 ! T cell mediated immunity [Term] id: GO:0002718 name: regulation of cytokine production involved in immune response namespace: biological_process alt_id: GO:0002739 alt_id: GO:0002742 def: "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] synonym: "regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "regulation of cytokine secretion involved in immune response" NARROW [] is_a: GO:0001817 ! regulation of cytokine production is_a: GO:0002700 ! regulation of production of molecular mediator of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002367 ! cytokine production involved in immune response relationship: regulates GO:0002367 ! cytokine production involved in immune response [Term] id: GO:0002719 name: negative regulation of cytokine production involved in immune response namespace: biological_process alt_id: GO:0002740 alt_id: GO:0002743 def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." [GOC:add] synonym: "down regulation of cytokine production during immune response" RELATED [] synonym: "down-regulation of cytokine production during immune response" EXACT [] synonym: "downregulation of cytokine production during immune response" RELATED [] synonym: "inhibition of cytokine production during immune response" RELATED [] synonym: "negative regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "negative regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "negative regulation of cytokine secretion involved in immune response" NARROW [] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:0002701 ! negative regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002367 ! cytokine production involved in immune response relationship: negatively_regulates GO:0002367 ! cytokine production involved in immune response [Term] id: GO:0002720 name: positive regulation of cytokine production involved in immune response namespace: biological_process alt_id: GO:0002741 alt_id: GO:0002744 def: "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." [GOC:add] synonym: "activation of cytokine production during immune response" NARROW [] synonym: "positive regulation of cytokine biosynthetic process involved in immune response" NARROW [] synonym: "positive regulation of cytokine production during immune response" RELATED [GOC:dph] synonym: "positive regulation of cytokine secretion involved in immune response" NARROW [] synonym: "stimulation of cytokine production during immune response" NARROW [] synonym: "up regulation of cytokine production during immune response" RELATED [] synonym: "up-regulation of cytokine production during immune response" RELATED [] synonym: "upregulation of cytokine production during immune response" RELATED [] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:0002702 ! positive regulation of production of molecular mediator of immune response is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002367 ! cytokine production involved in immune response relationship: positively_regulates GO:0002367 ! cytokine production involved in immune response [Term] id: GO:0002724 name: regulation of T cell cytokine production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "regulation of T lymphocyte cytokine production" EXACT [] synonym: "regulation of T-cell cytokine production" EXACT [] synonym: "regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002709 ! regulation of T cell mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002369 ! T cell cytokine production relationship: regulates GO:0002369 ! T cell cytokine production [Term] id: GO:0002725 name: negative regulation of T cell cytokine production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "down regulation of T cell cytokine production" EXACT [] synonym: "down-regulation of T cell cytokine production" EXACT [] synonym: "downregulation of T cell cytokine production" EXACT [] synonym: "inhibition of T cell cytokine production" NARROW [] synonym: "negative regulation of T lymphocyte cytokine production" EXACT [] synonym: "negative regulation of T-cell cytokine production" EXACT [] synonym: "negative regulation of T-lymphocyte cytokine production" EXACT [] is_a: GO:0002710 ! negative regulation of T cell mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002369 ! T cell cytokine production relationship: negatively_regulates GO:0002369 ! T cell cytokine production [Term] id: GO:0002726 name: positive regulation of T cell cytokine production namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." [GOC:add] synonym: "activation of T cell cytokine production" NARROW [] synonym: "positive regulation of T lymphocyte cytokine production" EXACT [] synonym: "positive regulation of T-cell cytokine production" EXACT [] synonym: "positive regulation of T-lymphocyte cytokine production" EXACT [] synonym: "stimulation of T cell cytokine production" NARROW [] synonym: "up regulation of T cell cytokine production" EXACT [] synonym: "up-regulation of T cell cytokine production" EXACT [] synonym: "upregulation of T cell cytokine production" EXACT [] is_a: GO:0002711 ! positive regulation of T cell mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002724 ! regulation of T cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002369 ! T cell cytokine production relationship: positively_regulates GO:0002369 ! T cell cytokine production [Term] id: GO:0002730 name: regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity is_a: GO:0002718 ! regulation of cytokine production involved in immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002371 ! dendritic cell cytokine production relationship: regulates GO:0002371 ! dendritic cell cytokine production [Term] id: GO:0002731 name: negative regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "down regulation of dendritic cell cytokine production" EXACT [] synonym: "down-regulation of dendritic cell cytokine production" EXACT [] synonym: "downregulation of dendritic cell cytokine production" EXACT [] synonym: "inhibition of dendritic cell cytokine production" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002719 ! negative regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002371 ! dendritic cell cytokine production relationship: negatively_regulates GO:0002371 ! dendritic cell cytokine production [Term] id: GO:0002732 name: positive regulation of dendritic cell cytokine production namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." [GOC:add] synonym: "activation of dendritic cell cytokine production" NARROW [] synonym: "stimulation of dendritic cell cytokine production" NARROW [] synonym: "up regulation of dendritic cell cytokine production" EXACT [] synonym: "up-regulation of dendritic cell cytokine production" EXACT [] synonym: "upregulation of dendritic cell cytokine production" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002720 ! positive regulation of cytokine production involved in immune response is_a: GO:0002730 ! regulation of dendritic cell cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002371 ! dendritic cell cytokine production relationship: positively_regulates GO:0002371 ! dendritic cell cytokine production [Term] id: GO:0002761 name: regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] is_a: GO:0045637 ! regulation of myeloid cell differentiation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002573 ! myeloid leukocyte differentiation relationship: regulates GO:0002573 ! myeloid leukocyte differentiation [Term] id: GO:0002762 name: negative regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "down regulation of myeloid leukocyte differentiation" EXACT [] synonym: "down-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "downregulation of myeloid leukocyte differentiation" EXACT [] synonym: "inhibition of myeloid leukocyte differentiation" NARROW [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation relationship: negatively_regulates GO:0002573 ! myeloid leukocyte differentiation [Term] id: GO:0002763 name: positive regulation of myeloid leukocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." [GOC:add] synonym: "activation of myeloid leukocyte differentiation" NARROW [] synonym: "stimulation of myeloid leukocyte differentiation" NARROW [] synonym: "up regulation of myeloid leukocyte differentiation" EXACT [] synonym: "up-regulation of myeloid leukocyte differentiation" EXACT [] synonym: "upregulation of myeloid leukocyte differentiation" EXACT [] is_a: GO:0002761 ! regulation of myeloid leukocyte differentiation is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002573 ! myeloid leukocyte differentiation relationship: positively_regulates GO:0002573 ! myeloid leukocyte differentiation [Term] id: GO:0002790 name: peptide secretion namespace: biological_process def: "The controlled release of a peptide from a cell or a tissue." [GOC:add] is_a: GO:0015833 ! peptide transport is_a: GO:0046903 ! secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:16670 ! peptide [Term] id: GO:0002791 name: regulation of peptide secretion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of peptide secretion." [GOC:add] is_a: GO:0051046 ! regulation of secretion is_a: GO:0090087 ! regulation of peptide transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002790 ! peptide secretion relationship: regulates GO:0002790 ! peptide secretion [Term] id: GO:0002792 name: negative regulation of peptide secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "down regulation of peptide secretion" EXACT [] synonym: "down-regulation of peptide secretion" EXACT [] synonym: "downregulation of peptide secretion" EXACT [] synonym: "inhibition of peptide secretion" NARROW [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051048 ! negative regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002790 ! peptide secretion relationship: negatively_regulates GO:0002790 ! peptide secretion [Term] id: GO:0002793 name: positive regulation of peptide secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of peptide secretion." [GOC:add] synonym: "activation of peptide secretion" NARROW [] synonym: "stimulation of peptide secretion" NARROW [] synonym: "up regulation of peptide secretion" EXACT [] synonym: "up-regulation of peptide secretion" EXACT [] synonym: "upregulation of peptide secretion" EXACT [] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0051047 ! positive regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002790 ! peptide secretion relationship: positively_regulates GO:0002790 ! peptide secretion [Term] id: GO:0002819 name: regulation of adaptive immune response namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response." [GOC:add] is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002250 ! adaptive immune response relationship: regulates GO:0002250 ! adaptive immune response [Term] id: GO:0002820 name: negative regulation of adaptive immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "down regulation of adaptive immune response" EXACT [] synonym: "down-regulation of adaptive immune response" EXACT [] synonym: "downregulation of adaptive immune response" EXACT [] synonym: "inhibition of adaptive immune response" NARROW [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050777 ! negative regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002250 ! adaptive immune response relationship: negatively_regulates GO:0002250 ! adaptive immune response [Term] id: GO:0002821 name: positive regulation of adaptive immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." [GOC:add] synonym: "activation of adaptive immune response" NARROW [] synonym: "stimulation of adaptive immune response" NARROW [] synonym: "up regulation of adaptive immune response" EXACT [] synonym: "up-regulation of adaptive immune response" EXACT [] synonym: "upregulation of adaptive immune response" EXACT [] is_a: GO:0002819 ! regulation of adaptive immune response is_a: GO:0050778 ! positive regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002250 ! adaptive immune response relationship: positively_regulates GO:0002250 ! adaptive immune response [Term] id: GO:0002822 name: regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002819 ! regulation of adaptive immune response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: in_taxon NCBITaxon:7776 {all_only="true"} ! Gnathostomata relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002823 name: negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002820 ! negative regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: negatively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002824 name: positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." [GOC:add, GOC:mtg_sensu] is_a: GO:0002821 ! positive regulation of adaptive immune response is_a: GO:0002822 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains relationship: positively_regulates GO:0002460 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [Term] id: GO:0002831 name: regulation of response to biotic stimulus namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009607 ! response to biotic stimulus relationship: regulates GO:0009607 ! response to biotic stimulus [Term] id: GO:0002832 name: negative regulation of response to biotic stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "down regulation of response to biotic stimulus" EXACT [] synonym: "down-regulation of response to biotic stimulus" EXACT [] synonym: "downregulation of response to biotic stimulus" EXACT [] synonym: "inhibition of response to biotic stimulus" NARROW [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009607 ! response to biotic stimulus relationship: negatively_regulates GO:0009607 ! response to biotic stimulus [Term] id: GO:0002833 name: positive regulation of response to biotic stimulus namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." [GOC:add] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "activation of response to biotic stimulus" NARROW [] synonym: "stimulation of response to biotic stimulus" NARROW [] synonym: "up regulation of response to biotic stimulus" EXACT [] synonym: "up-regulation of response to biotic stimulus" EXACT [] synonym: "upregulation of response to biotic stimulus" EXACT [] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009607 ! response to biotic stimulus relationship: positively_regulates GO:0009607 ! response to biotic stimulus [Term] id: GO:0002886 name: regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] is_a: GO:0002703 ! regulation of leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002444 ! myeloid leukocyte mediated immunity relationship: regulates GO:0002444 ! myeloid leukocyte mediated immunity [Term] id: GO:0002887 name: negative regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "down regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "down-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "downregulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "inhibition of myeloid leukocyte mediated immunity" NARROW [] is_a: GO:0002704 ! negative regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity relationship: negatively_regulates GO:0002444 ! myeloid leukocyte mediated immunity [Term] id: GO:0002888 name: positive regulation of myeloid leukocyte mediated immunity namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." [GOC:add] synonym: "activation of myeloid leukocyte mediated immunity" NARROW [] synonym: "stimulation of myeloid leukocyte mediated immunity" NARROW [] synonym: "up regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "up-regulation of myeloid leukocyte mediated immunity" EXACT [] synonym: "upregulation of myeloid leukocyte mediated immunity" EXACT [] is_a: GO:0002705 ! positive regulation of leukocyte mediated immunity is_a: GO:0002886 ! regulation of myeloid leukocyte mediated immunity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity relationship: positively_regulates GO:0002444 ! myeloid leukocyte mediated immunity [Term] id: GO:0002932 name: tendon sheath development namespace: biological_process def: "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." [PMID:20696843] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000304 ! tendon sheath relationship: part_of GO:0035989 ! tendon development relationship: results_in_development_of UBERON:0000304 ! tendon sheath created_by: hjd creation_date: 2012-04-23T02:11:22Z [Term] id: GO:0003002 name: regionalization namespace: biological_process def: "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:isa_complete] synonym: "pattern formation" RELATED [GOC:dph] is_a: GO:0007389 ! pattern specification process [Term] id: GO:0003006 name: developmental process involved in reproduction namespace: biological_process def: "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." [GOC:dph, GOC:isa_complete] synonym: "puberty" NARROW [GOC:dph] synonym: "reproductive developmental process" RELATED [GOC:dph, GOC:tb] is_a: GO:0022414 ! reproductive process is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: part_of GO:0000003 ! reproduction [Term] id: GO:0003007 name: heart morphogenesis namespace: biological_process def: "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:dph, GOC:isa_complete] synonym: "cardiac morphogenesis" RELATED [] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007100 ! primary circulatory organ relationship: part_of GO:0007507 ! heart development relationship: results_in_morphogenesis_of UBERON:0007100 ! primary circulatory organ [Term] id: GO:0003008 name: system process namespace: biological_process def: "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." [GOC:mtg_cardio] synonym: "organ system process" EXACT [] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0003009 name: skeletal muscle contraction namespace: biological_process def: "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." [GOC:mtg_cardio, GOC:mtg_muscle] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue relationship: occurs_in UBERON:0001134 ! skeletal muscle tissue relationship: part_of GO:0050881 ! musculoskeletal movement [Term] id: GO:0003012 name: muscle system process namespace: biological_process def: "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." [GOC:mtg_cardio] subset: goslim_drosophila subset: goslim_generic synonym: "muscle physiological process" RELATED [] is_a: GO:0003008 ! system process [Term] id: GO:0003013 name: circulatory system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." [GOC:mtg_cardio] subset: goslim_chembl subset: goslim_generic xref: Wikipedia:Circulatory_system is_a: GO:0003008 ! system process [Term] id: GO:0003014 name: renal system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." [GOC:cjm, GOC:mtg_cardio, GOC:mtg_kidney_jan10] subset: goslim_generic synonym: "excretory system process" EXACT [] synonym: "kidney system process" RELATED [] is_a: GO:0003008 ! system process [Term] id: GO:0003015 name: heart process namespace: biological_process def: "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:mtg_cardio] synonym: "cardiac process" RELATED [] is_a: GO:0003013 ! circulatory system process [Term] id: GO:0003016 name: respiratory system process namespace: biological_process alt_id: GO:0010802 def: "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." [GOC:dph, GOC:mtg_cardio, GOC:tb] subset: goslim_generic synonym: "respiratory gaseous exchange" EXACT [] is_a: GO:0003008 ! system process relationship: part_of GO:0007585 ! respiratory gaseous exchange by respiratory system [Term] id: GO:0003096 name: renal sodium ion transport namespace: biological_process def: "The directed movement of sodium ions (Na+) by the renal system." [GOC:mtg_cardio] is_a: GO:0003014 ! renal system process is_a: GO:0006814 ! sodium ion transport intersection_of: GO:0006814 ! sodium ion transport intersection_of: occurs_in UBERON:0001008 ! renal system relationship: occurs_in UBERON:0001008 ! renal system [Term] id: GO:0003133 name: endodermal-mesodermal cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." [GOC:mtg_heart] synonym: "endodermal-mesodermal cell signalling" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location UBERON:0000926 ! mesoderm intersection_of: has_start_location UBERON:0000925 ! endoderm relationship: has_end_location UBERON:0000926 ! mesoderm relationship: has_start_location UBERON:0000925 ! endoderm created_by: tb creation_date: 2009-09-22T03:10:29Z [Term] id: GO:0003142 name: cardiogenic plate morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." [GOC:mtg_heart] synonym: "cardiac crescent morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004139 ! cardiogenic plate relationship: part_of GO:0003007 ! heart morphogenesis relationship: results_in_morphogenesis_of UBERON:0004139 ! cardiogenic plate created_by: tb creation_date: 2009-09-22T04:12:18Z [Term] id: GO:0003143 name: embryonic heart tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004141 ! heart tube relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0035050 ! embryonic heart tube development relationship: part_of GO:0048562 ! embryonic organ morphogenesis relationship: results_in_morphogenesis_of UBERON:0004141 ! heart tube created_by: tb creation_date: 2009-09-22T04:21:17Z [Term] id: GO:0003144 name: embryonic heart tube formation namespace: biological_process def: "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." [GOC:mtg_heart] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0004141 ! heart tube relationship: part_of GO:0003143 ! embryonic heart tube morphogenesis relationship: results_in_formation_of UBERON:0004141 ! heart tube created_by: tb creation_date: 2009-09-22T04:22:34Z [Term] id: GO:0003145 name: embryonic heart tube formation via epithelial folding namespace: biological_process def: "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis." [GOC:mtg_heart] is_a: GO:0003144 ! embryonic heart tube formation created_by: tb creation_date: 2009-09-22T04:26:03Z [Term] id: GO:0003147 name: neural crest cell migration involved in heart formation namespace: biological_process def: "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0060914 ! heart formation relationship: part_of GO:0061308 ! cardiac neural crest cell development involved in heart development created_by: tb creation_date: 2009-09-22T04:29:55Z [Term] id: GO:0003148 name: outflow tract septum morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." [GOC:mtg_heart] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004142 ! outflow tract septum relationship: part_of GO:0003151 ! outflow tract morphogenesis relationship: results_in_morphogenesis_of UBERON:0004142 ! outflow tract septum created_by: tb creation_date: 2009-09-22T07:51:01Z [Term] id: GO:0003149 name: membranous septum morphogenesis namespace: biological_process def: "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004666 ! interventricular septum membranous part relationship: part_of GO:0060412 ! ventricular septum morphogenesis relationship: results_in_morphogenesis_of UBERON:0004666 ! interventricular septum membranous part created_by: tb creation_date: 2009-09-22T07:51:41Z [Term] id: GO:0003150 name: muscular septum morphogenesis namespace: biological_process def: "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." [GOC:mtg_heart] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004667 ! interventricular septum muscular part relationship: part_of GO:0060412 ! ventricular septum morphogenesis relationship: results_in_morphogenesis_of UBERON:0004667 ! interventricular septum muscular part created_by: tb creation_date: 2009-09-22T07:53:28Z [Term] id: GO:0003151 name: outflow tract morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_heart, UBERON:0004145] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004145 ! outflow tract relationship: part_of GO:0003007 ! heart morphogenesis relationship: results_in_morphogenesis_of UBERON:0004145 ! outflow tract created_by: tb creation_date: 2009-09-22T07:59:24Z [Term] id: GO:0003152 name: morphogenesis of an epithelial fold involved in embryonic heart tube formation namespace: biological_process def: "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation." [GOC:mtg_heart] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: part_of GO:0003144 ! embryonic heart tube formation relationship: part_of GO:0003145 ! embryonic heart tube formation via epithelial folding created_by: tb creation_date: 2009-09-23T10:10:24Z [Term] id: GO:0003156 name: regulation of animal organ formation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." [GOC:dph, GOC:mtg_heart, GOC:tb] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048645 ! animal organ formation relationship: regulates GO:0048645 ! animal organ formation created_by: tb creation_date: 2009-09-30T11:21:09Z [Term] id: GO:0003157 name: endocardium development namespace: biological_process def: "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002165 ! endocardium relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0002165 ! endocardium created_by: dph creation_date: 2009-10-01T12:42:27Z [Term] id: GO:0003158 name: endothelium development namespace: biological_process def: "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001986 ! endothelium relationship: results_in_development_of UBERON:0001986 ! endothelium created_by: dph creation_date: 2009-10-01T12:50:57Z [Term] id: GO:0003159 name: morphogenesis of an endothelium namespace: biological_process def: "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001986 ! endothelium relationship: part_of GO:0003158 ! endothelium development relationship: results_in_morphogenesis_of UBERON:0001986 ! endothelium created_by: dph creation_date: 2009-10-01T01:34:06Z [Term] id: GO:0003160 name: endocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002165 ! endocardium relationship: part_of GO:0003157 ! endocardium development relationship: results_in_morphogenesis_of UBERON:0002165 ! endocardium created_by: dph creation_date: 2009-10-01T01:37:26Z [Term] id: GO:0003161 name: cardiac conduction system development namespace: biological_process def: "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." [GOC:mtg_heart] synonym: "cardiac impulse conducting system development" EXACT [GOC:mtg_heart] synonym: "heart conduction system development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002350 ! conducting system of heart relationship: results_in_development_of UBERON:0002350 ! conducting system of heart created_by: dph creation_date: 2009-10-01T01:57:16Z [Term] id: GO:0003162 name: atrioventricular node development namespace: biological_process def: "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." [GOC:mtg_heart] synonym: "AV node development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002352 ! atrioventricular node relationship: part_of GO:0003161 ! cardiac conduction system development relationship: results_in_development_of UBERON:0002352 ! atrioventricular node created_by: dph creation_date: 2009-10-01T02:05:13Z [Term] id: GO:0003163 name: sinoatrial node development namespace: biological_process def: "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." [GOC:mtg_heart] synonym: "SA node development" EXACT [GOC:mtg_heart] synonym: "SAN development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0003228 ! atrial cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002351 ! sinoatrial node relationship: part_of GO:0003161 ! cardiac conduction system development relationship: results_in_development_of UBERON:0002351 ! sinoatrial node created_by: dph creation_date: 2009-10-01T02:06:09Z [Term] id: GO:0003164 name: His-Purkinje system development namespace: biological_process def: "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004146 ! His-Purkinje system relationship: part_of GO:0003161 ! cardiac conduction system development relationship: results_in_development_of UBERON:0004146 ! His-Purkinje system created_by: dph creation_date: 2009-10-01T02:07:12Z [Term] id: GO:0003165 name: Purkinje myocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber development" EXACT [] is_a: GO:0003229 ! ventricular cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002354 ! cardiac Purkinje fiber relationship: part_of GO:0003164 ! His-Purkinje system development relationship: results_in_development_of UBERON:0002354 ! cardiac Purkinje fiber created_by: dph creation_date: 2009-10-01T02:07:50Z [Term] id: GO:0003168 name: Purkinje myocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "cardiac Purkinje fiber cell differentiation" EXACT [] is_a: GO:0060932 ! His-Purkinje system cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002068 ! Purkinje myocyte relationship: part_of GO:0003165 ! Purkinje myocyte development relationship: results_in_acquisition_of_features_of CL:0002068 ! Purkinje myocyte created_by: dph creation_date: 2009-10-01T02:49:54Z [Term] id: GO:0003169 name: coronary vein morphogenesis namespace: biological_process def: "The process in which the anatomical structures of veins of the heart are generated and organized." [GOC:mtg_heart] is_a: GO:0048845 ! venous blood vessel morphogenesis is_a: GO:0060977 ! coronary vasculature morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004148 ! cardiac vein relationship: results_in_morphogenesis_of UBERON:0004148 ! cardiac vein created_by: dph creation_date: 2009-10-08T10:45:41Z [Term] id: GO:0003197 name: endocardial cushion development namespace: biological_process def: "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002062 ! endocardial cushion relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0002062 ! endocardial cushion created_by: dph creation_date: 2009-10-08T01:17:43Z [Term] id: GO:0003203 name: endocardial cushion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002062 ! endocardial cushion relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003197 ! endocardial cushion development relationship: results_in_morphogenesis_of UBERON:0002062 ! endocardial cushion created_by: dph creation_date: 2009-10-08T01:43:22Z [Term] id: GO:0003204 name: cardiac skeleton development namespace: biological_process def: "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." [GOC:mtg_heart] synonym: "heart fibrous skeleton development" EXACT [GOC:mtg_heart] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004292 ! cardiac skeleton relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0004292 ! cardiac skeleton created_by: dph creation_date: 2009-10-13T09:05:04Z [Term] id: GO:0003205 name: cardiac chamber development namespace: biological_process def: "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004151 ! cardiac chamber relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0004151 ! cardiac chamber created_by: dph creation_date: 2009-10-13T09:11:18Z [Term] id: GO:0003206 name: cardiac chamber morphogenesis namespace: biological_process def: "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004151 ! cardiac chamber relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003205 ! cardiac chamber development relationship: results_in_morphogenesis_of UBERON:0004151 ! cardiac chamber created_by: dph creation_date: 2009-10-13T09:14:51Z [Term] id: GO:0003207 name: cardiac chamber formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." [GOC:mtg_heart] synonym: "heart chamber formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0004151 ! cardiac chamber relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: results_in_formation_of UBERON:0004151 ! cardiac chamber created_by: dph creation_date: 2009-10-13T09:29:13Z [Term] id: GO:0003208 name: cardiac ventricle morphogenesis namespace: biological_process def: "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002082 ! cardiac ventricle relationship: part_of GO:0003231 ! cardiac ventricle development relationship: results_in_morphogenesis_of UBERON:0002082 ! cardiac ventricle created_by: dph creation_date: 2009-10-13T09:38:44Z [Term] id: GO:0003209 name: cardiac atrium morphogenesis namespace: biological_process def: "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002081 ! cardiac atrium relationship: part_of GO:0003230 ! cardiac atrium development relationship: results_in_morphogenesis_of UBERON:0002081 ! cardiac atrium created_by: dph creation_date: 2009-10-13T09:39:44Z [Term] id: GO:0003210 name: cardiac atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002081 ! cardiac atrium relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: results_in_formation_of UBERON:0002081 ! cardiac atrium created_by: dph creation_date: 2009-10-13T09:44:25Z [Term] id: GO:0003211 name: cardiac ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002082 ! cardiac ventricle relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis relationship: results_in_formation_of UBERON:0002082 ! cardiac ventricle created_by: dph creation_date: 2009-10-13T09:46:27Z [Term] id: GO:0003212 name: cardiac left atrium morphogenesis namespace: biological_process def: "The process in which the left cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002079 ! left cardiac atrium relationship: results_in_morphogenesis_of UBERON:0002079 ! left cardiac atrium created_by: dph creation_date: 2009-10-13T09:48:16Z [Term] id: GO:0003213 name: cardiac right atrium morphogenesis namespace: biological_process def: "The process in which the right cardiac atrium is generated and organized." [GOC:mtg_heart] is_a: GO:0003209 ! cardiac atrium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002078 ! right cardiac atrium relationship: results_in_morphogenesis_of UBERON:0002078 ! right cardiac atrium created_by: dph creation_date: 2009-10-13T09:49:03Z [Term] id: GO:0003214 name: cardiac left ventricle morphogenesis namespace: biological_process def: "The process in which the left cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002084 ! heart left ventricle relationship: results_in_morphogenesis_of UBERON:0002084 ! heart left ventricle created_by: dph creation_date: 2009-10-13T09:50:08Z [Term] id: GO:0003215 name: cardiac right ventricle morphogenesis namespace: biological_process def: "The process in which the right cardiac ventricle is generated and organized." [GOC:mtg_heart] is_a: GO:0003208 ! cardiac ventricle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002080 ! heart right ventricle relationship: results_in_morphogenesis_of UBERON:0002080 ! heart right ventricle created_by: dph creation_date: 2009-10-13T09:50:57Z [Term] id: GO:0003216 name: cardiac left atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002079 ! left cardiac atrium relationship: part_of GO:0003212 ! cardiac left atrium morphogenesis relationship: results_in_formation_of UBERON:0002079 ! left cardiac atrium created_by: dph creation_date: 2009-10-13T09:52:31Z [Term] id: GO:0003217 name: cardiac right atrium formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." [GOC:mtg_heart] is_a: GO:0003210 ! cardiac atrium formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002078 ! right cardiac atrium relationship: part_of GO:0003213 ! cardiac right atrium morphogenesis relationship: results_in_formation_of UBERON:0002078 ! right cardiac atrium created_by: dph creation_date: 2009-10-13T09:53:12Z [Term] id: GO:0003218 name: cardiac left ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002084 ! heart left ventricle relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis relationship: results_in_formation_of UBERON:0002084 ! heart left ventricle created_by: dph creation_date: 2009-10-13T09:54:33Z [Term] id: GO:0003219 name: cardiac right ventricle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." [GOC:mtg_heart] is_a: GO:0003211 ! cardiac ventricle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002080 ! heart right ventricle relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis relationship: results_in_formation_of UBERON:0002080 ! heart right ventricle created_by: dph creation_date: 2009-10-13T09:55:38Z [Term] id: GO:0003220 name: left ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "left ventricular myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003382 ! cardiac muscle of left ventricle relationship: part_of GO:0003214 ! cardiac left ventricle morphogenesis relationship: results_in_morphogenesis_of UBERON:0003382 ! cardiac muscle of left ventricle created_by: dph creation_date: 2009-10-13T10:18:05Z [Term] id: GO:0003221 name: right ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "right ventricle myocardium morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003381 ! cardiac muscle of right ventricle relationship: part_of GO:0003215 ! cardiac right ventricle morphogenesis relationship: results_in_morphogenesis_of UBERON:0003381 ! cardiac muscle of right ventricle created_by: dph creation_date: 2009-10-13T10:26:33Z [Term] id: GO:0003222 name: ventricular trabecula myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized." [GOC:mtg_heart] synonym: "trabecula carnea morphogenesis" RELATED [GOC:dph] is_a: GO:0055010 ! ventricular cardiac muscle tissue morphogenesis is_a: GO:0061384 ! heart trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004126 ! trabecular layer of ventricle relationship: results_in_morphogenesis_of UBERON:0004126 ! trabecular layer of ventricle created_by: dph creation_date: 2009-10-13T10:33:00Z [Term] id: GO:0003225 name: left ventricular trabecular myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003220 ! left ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005064 ! left ventricular trabecular myocardium relationship: results_in_morphogenesis_of UBERON:0005064 ! left ventricular trabecular myocardium created_by: dph creation_date: 2009-10-13T10:45:09Z [Term] id: GO:0003227 name: right ventricular trabecular myocardium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the right ventricular myocardium are generated and organized." [GOC:mtg_heart] is_a: GO:0003221 ! right ventricular cardiac muscle tissue morphogenesis is_a: GO:0003222 ! ventricular trabecula myocardium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005066 ! right ventricular trabecular myocardium relationship: results_in_morphogenesis_of UBERON:0005066 ! right ventricular trabecular myocardium created_by: dph creation_date: 2009-10-13T10:50:59Z [Term] id: GO:0003228 name: atrial cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "atrial myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004490 ! cardiac muscle tissue of atrium relationship: results_in_development_of UBERON:0004490 ! cardiac muscle tissue of atrium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22614" xsd:anyURI created_by: dph creation_date: 2009-10-13T10:53:18Z [Term] id: GO:0003229 name: ventricular cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "ventricular myocardium development" EXACT [GOC:mtg_heart] is_a: GO:0048738 ! cardiac muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: results_in_development_of UBERON:0018649 ! cardiac muscle tissue of ventricle created_by: dph creation_date: 2009-10-13T10:56:01Z [Term] id: GO:0003230 name: cardiac atrium development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002081 ! cardiac atrium relationship: results_in_development_of UBERON:0002081 ! cardiac atrium created_by: dph creation_date: 2009-10-13T11:02:07Z [Term] id: GO:0003231 name: cardiac ventricle development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002082 ! cardiac ventricle relationship: results_in_development_of UBERON:0002082 ! cardiac ventricle created_by: dph creation_date: 2009-10-13T11:03:16Z [Term] id: GO:0003235 name: sinus venosus development namespace: biological_process def: "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002063 ! sinus venosus relationship: results_in_development_of UBERON:0002063 ! sinus venosus created_by: dph creation_date: 2009-10-13T11:12:34Z [Term] id: GO:0003236 name: sinus venosus morphogenesis namespace: biological_process def: "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002063 ! sinus venosus relationship: part_of GO:0003235 ! sinus venosus development relationship: results_in_morphogenesis_of UBERON:0002063 ! sinus venosus created_by: dph creation_date: 2009-10-13T11:16:52Z [Term] id: GO:0003237 name: sinus venosus formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002063 ! sinus venosus relationship: part_of GO:0003236 ! sinus venosus morphogenesis relationship: results_in_formation_of UBERON:0002063 ! sinus venosus created_by: dph creation_date: 2009-10-13T11:18:34Z [Term] id: GO:0003238 name: conus arteriosus development namespace: biological_process def: "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003205 ! cardiac chamber development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003983 ! conus arteriosus relationship: results_in_development_of UBERON:0003983 ! conus arteriosus created_by: dph creation_date: 2009-10-13T11:20:57Z [Term] id: GO:0003239 name: conus arteriosus morphogenesis namespace: biological_process def: "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003206 ! cardiac chamber morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003983 ! conus arteriosus relationship: part_of GO:0003238 ! conus arteriosus development relationship: results_in_morphogenesis_of UBERON:0003983 ! conus arteriosus created_by: dph creation_date: 2009-10-13T11:25:04Z [Term] id: GO:0003240 name: conus arteriosus formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." [GOC:mtg_heart] is_a: GO:0003207 ! cardiac chamber formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003983 ! conus arteriosus relationship: part_of GO:0003239 ! conus arteriosus morphogenesis relationship: results_in_formation_of UBERON:0003983 ! conus arteriosus created_by: dph creation_date: 2009-10-13T11:25:47Z [Term] id: GO:0003241 name: growth involved in heart morphogenesis namespace: biological_process def: "Developmental growth that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0060560 ! developmental growth involved in morphogenesis intersection_of: GO:0040007 ! growth intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0060419 ! heart growth created_by: dph creation_date: 2009-10-13T11:28:46Z [Term] id: GO:0003245 name: cardiac muscle tissue growth involved in heart morphogenesis namespace: biological_process def: "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." [GOC:mtg_heart] is_a: GO:0003241 ! growth involved in heart morphogenesis is_a: GO:0055017 ! cardiac muscle tissue growth intersection_of: GO:0055017 ! cardiac muscle tissue growth intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0055008 ! cardiac muscle tissue morphogenesis created_by: dph creation_date: 2009-10-13T11:44:21Z [Term] id: GO:0003248 name: heart capillary growth namespace: biological_process def: "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." [GOC:mtg_heart] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0006966 ! coronary capillary relationship: part_of GO:0060419 ! heart growth relationship: part_of GO:0060976 ! coronary vasculature development relationship: results_in_growth_of UBERON:0006966 ! coronary capillary created_by: dph creation_date: 2009-10-13T11:53:12Z [Term] id: GO:0003253 name: cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." [GOC:mtg_heart] is_a: GO:0001755 ! neural crest cell migration is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0061309 ! cardiac neural crest cell development involved in outflow tract morphogenesis created_by: dph creation_date: 2009-10-13T02:14:16Z [Term] id: GO:0003260 name: cardioblast migration namespace: biological_process def: "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:mtg_heart] is_a: GO:0060974 ! cell migration involved in heart formation intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0002664 ! cardioblast relationship: results_in_movement_of CL:0002664 ! cardioblast created_by: dph creation_date: 2009-10-15T01:52:25Z [Term] id: GO:0003272 name: endocardial cushion formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart, PMID:15797462] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002062 ! endocardial cushion relationship: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: results_in_formation_of UBERON:0002062 ! endocardial cushion created_by: dph creation_date: 2009-10-20T08:53:19Z [Term] id: GO:0003273 name: cell migration involved in endocardial cushion formation namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0003272 ! endocardial cushion formation relationship: part_of GO:0003272 ! endocardial cushion formation created_by: dph creation_date: 2009-10-20T09:08:44Z [Term] id: GO:0003275 name: apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in outflow tract morphogenesis" NARROW [] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2009-10-20T09:30:01Z [Term] id: GO:0003277 name: apoptotic process involved in endocardial cushion morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in endocardial cushion morphogenesis" NARROW [] is_a: GO:0003278 ! apoptotic process involved in heart morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: part_of GO:0003203 ! endocardial cushion morphogenesis created_by: dph creation_date: 2009-10-20T09:37:03Z [Term] id: GO:0003278 name: apoptotic process involved in heart morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of the heart." [GOC:mtg_apoptosis, GOC:mtg_heart] synonym: "apoptosis involved in heart morphogenesis" NARROW [] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2009-10-20T09:40:22Z [Term] id: GO:0003279 name: cardiac septum development namespace: biological_process def: "The progression of a cardiac septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] synonym: "heart septum development" EXACT [GOC:mtg_heart] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002099 ! cardiac septum relationship: part_of GO:0003205 ! cardiac chamber development relationship: results_in_development_of UBERON:0002099 ! cardiac septum created_by: dph creation_date: 2009-10-20T09:45:13Z [Term] id: GO:0003281 name: ventricular septum development namespace: biological_process def: "The progression of the ventricular septum over time from its formation to the mature structure." [GOC:mtg_heart] synonym: "interventricular septum development" EXACT [GOC:mtg_heart] synonym: "septum inferius development" NARROW [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002094 ! interventricular septum relationship: part_of GO:0003231 ! cardiac ventricle development relationship: results_in_development_of UBERON:0002094 ! interventricular septum created_by: dph creation_date: 2009-10-20T10:04:51Z [Term] id: GO:0003283 name: atrial septum development namespace: biological_process def: "The progression of the atrial septum over time, from its initial formation to the mature structure." [GOC:mtg_heart] is_a: GO:0003279 ! cardiac septum development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002085 ! interatrial septum relationship: part_of GO:0003230 ! cardiac atrium development relationship: results_in_development_of UBERON:0002085 ! interatrial septum created_by: dph creation_date: 2009-10-20T10:10:38Z [Term] id: GO:0003292 name: cardiac septum cell differentiation namespace: biological_process def: "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000022 ! cardiac septum cell relationship: part_of GO:0003279 ! cardiac septum development relationship: results_in_acquisition_of_features_of CL:2000022 ! cardiac septum cell created_by: dph creation_date: 2009-10-20T11:03:46Z [Term] id: GO:0003298 name: physiological muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." [GOC:mtg_heart] is_a: GO:0014896 ! muscle hypertrophy created_by: dph creation_date: 2009-10-22T09:24:51Z [Term] id: GO:0003300 name: cardiac muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." [GOC:mtg_heart] is_a: GO:0014897 ! striated muscle hypertrophy created_by: dph creation_date: 2009-10-22T10:33:56Z [Term] id: GO:0003301 name: physiological cardiac muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] is_a: GO:0003298 ! physiological muscle hypertrophy is_a: GO:0003300 ! cardiac muscle hypertrophy relationship: part_of GO:0055017 ! cardiac muscle tissue growth created_by: dph creation_date: 2009-10-22T10:38:10Z [Term] id: GO:0003309 name: type B pancreatic cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph, PMID:11076772] synonym: "pancreatic B cell differentiation" EXACT [GOC:mah] synonym: "pancreatic beta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000169 ! type B pancreatic cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0000169 ! type B pancreatic cell created_by: dph creation_date: 2009-10-26T09:27:23Z [Term] id: GO:0003310 name: pancreatic A cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph, PMID:11076772] synonym: "pancreatic alpha cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000171 ! pancreatic A cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0000171 ! pancreatic A cell created_by: dph creation_date: 2009-10-26T09:28:05Z [Term] id: GO:0003311 name: pancreatic D cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph, PMID:11076772] synonym: "pancreatic delta cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000173 ! pancreatic D cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0000173 ! pancreatic D cell created_by: dph creation_date: 2009-10-26T09:30:27Z [Term] id: GO:0003312 name: pancreatic PP cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph, PMID:11076772] synonym: "pancreatic polypeptide-producing cell differentiation" EXACT [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002275 ! pancreatic PP cell relationship: part_of GO:0031018 ! endocrine pancreas development relationship: results_in_acquisition_of_features_of CL:0002275 ! pancreatic PP cell created_by: dph creation_date: 2009-10-26T09:32:32Z [Term] id: GO:0003313 name: heart rudiment development namespace: biological_process def: "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GOC:mtg_heart] synonym: "heart cone development" EXACT [GOC:mtg_heart] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004291 ! heart rudiment relationship: part_of GO:0035050 ! embryonic heart tube development relationship: results_in_development_of UBERON:0004291 ! heart rudiment created_by: dph creation_date: 2009-10-27T08:32:40Z [Term] id: GO:0003314 name: heart rudiment morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the heart rudiment are generated and organized." [GOC:mtg_heart] synonym: "heart cone morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004291 ! heart rudiment relationship: part_of GO:0003313 ! heart rudiment development relationship: results_in_morphogenesis_of UBERON:0004291 ! heart rudiment created_by: dph creation_date: 2009-10-27T08:38:04Z [Term] id: GO:0003315 name: heart rudiment formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the heart rudiment." [GOC:mtg_heart] synonym: "heart cone formation" EXACT [GOC:mtg_heart] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0004291 ! heart rudiment relationship: part_of GO:0003314 ! heart rudiment morphogenesis relationship: results_in_formation_of UBERON:0004291 ! heart rudiment created_by: dph creation_date: 2009-10-27T08:43:37Z [Term] id: GO:0003322 name: pancreatic A cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon." [GOC:dph] synonym: "pancreatic alpha cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000171 ! pancreatic A cell relationship: part_of GO:0003310 ! pancreatic A cell differentiation relationship: results_in_development_of CL:0000171 ! pancreatic A cell created_by: dph creation_date: 2009-11-02T08:13:55Z [Term] id: GO:0003323 name: type B pancreatic cell development namespace: biological_process def: "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:dph] synonym: "pancreatic B cell development" EXACT [GOC:mah] synonym: "pancreatic beta cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000169 ! type B pancreatic cell relationship: part_of GO:0003309 ! type B pancreatic cell differentiation relationship: results_in_development_of CL:0000169 ! type B pancreatic cell created_by: dph creation_date: 2009-11-02T08:20:11Z [Term] id: GO:0003324 name: pancreatic D cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin." [GOC:dph] synonym: "pancreatic delta cell development" EXACT [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000173 ! pancreatic D cell relationship: part_of GO:0003311 ! pancreatic D cell differentiation relationship: results_in_development_of CL:0000173 ! pancreatic D cell created_by: dph creation_date: 2009-11-02T08:23:26Z [Term] id: GO:0003325 name: pancreatic PP cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." [GOC:dph] is_a: GO:0002068 ! glandular epithelial cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0002275 ! pancreatic PP cell relationship: part_of GO:0003312 ! pancreatic PP cell differentiation relationship: results_in_development_of CL:0002275 ! pancreatic PP cell created_by: dph creation_date: 2009-11-02T08:25:03Z [Term] id: GO:0003333 name: amino acid transmembrane transport namespace: biological_process def: "The process in which an amino acid is transported across a membrane." [GOC:dph, GOC:tb] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "amino acid membrane transport" EXACT [] is_a: GO:0006865 ! amino acid transport is_a: GO:1903825 ! organic acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33709 ! amino acid intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: dph creation_date: 2009-11-02T02:36:11Z [Term] id: GO:0003337 name: mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] synonym: "metanephric mesenchyme to epithelial transition" RELATED [GOC:dph] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0003338 ! metanephros morphogenesis relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis created_by: dph creation_date: 2009-11-24T09:29:49Z [Term] id: GO:0003338 name: metanephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephros are generated and organized." [GOC:dph, GOC:yaf] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000081 ! metanephros relationship: part_of GO:0001656 ! metanephros development relationship: results_in_morphogenesis_of UBERON:0000081 ! metanephros created_by: dph creation_date: 2009-11-24T09:32:09Z [Term] id: GO:0003339 name: regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: dph creation_date: 2009-11-24T09:43:04Z [Term] id: GO:0003340 name: negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:dph, GOC:yaf] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: negatively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: dph creation_date: 2009-11-24T09:46:12Z [Term] id: GO:0003341 name: cilium movement namespace: biological_process alt_id: GO:0036142 def: "The directed, self-propelled movement of a cilium." [GOC:dph, GOC:jl] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "ciliary motility" RELATED [] synonym: "cilium beating" RELATED [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "flagellar motility" RELATED [] synonym: "flagellar movement" NARROW [GOC:bf] synonym: "flagellum movement" NARROW [] synonym: "microtubule-based flagellum movement" EXACT [] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: process_has_causal_agent GO:0005874 ! microtubule intersection_of: results_in_movement_of GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: results_in_movement_of GO:0005929 ! cilium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2009-11-24T09:56:26Z [Term] id: GO:0003342 name: proepicardium development namespace: biological_process def: "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004160 ! proepicardium relationship: part_of GO:0003343 ! septum transversum development relationship: results_in_development_of UBERON:0004160 ! proepicardium created_by: dph creation_date: 2009-12-01T10:30:17Z [Term] id: GO:0003343 name: septum transversum development namespace: biological_process def: "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." [GOC:dph, PMID:18722343] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004161 ! septum transversum relationship: results_in_development_of UBERON:0004161 ! septum transversum created_by: dph creation_date: 2009-12-01T10:40:17Z [Term] id: GO:0003344 name: pericardium morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pericardium is generated and organized." [GOC:dph, PMID:18722343] is_a: GO:0002011 ! morphogenesis of an epithelial sheet is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002407 ! pericardium relationship: part_of GO:0060039 ! pericardium development relationship: results_in_morphogenesis_of UBERON:0002407 ! pericardium created_by: dph creation_date: 2009-12-01T10:46:34Z [Term] id: GO:0003348 name: cardiac endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." [GOC:dph, PMID:18722343] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010008 ! cardiac endothelial cell relationship: results_in_acquisition_of_features_of CL:0010008 ! cardiac endothelial cell created_by: dph creation_date: 2009-12-01T11:12:05Z [Term] id: GO:0003352 name: regulation of cilium movement namespace: biological_process alt_id: GO:1900172 def: "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "regulation of flagellar movement" RELATED [GOC:TermGenie] synonym: "regulation of flagellum movement" RELATED [] synonym: "regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003341 ! cilium movement relationship: regulates GO:0003341 ! cilium movement created_by: dph creation_date: 2009-12-03T10:12:00Z [Term] id: GO:0003353 name: positive regulation of cilium movement namespace: biological_process alt_id: GO:1900174 def: "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "positive regulation of flagellar movement" RELATED [GOC:TermGenie] synonym: "positive regulation of flagellum movement" RELATED [] synonym: "positive regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003341 ! cilium movement relationship: positively_regulates GO:0003341 ! cilium movement created_by: dph creation_date: 2009-12-03T10:16:10Z [Term] id: GO:0003354 name: negative regulation of cilium movement namespace: biological_process alt_id: GO:1900173 def: "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." [GOC:dph] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "negative regulation of flagellum movement" RELATED [] synonym: "negative regulation of microtubule-based flagellum movement" EXACT [] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003341 ! cilium movement relationship: negatively_regulates GO:0003341 ! cilium movement created_by: dph creation_date: 2009-12-03T10:17:47Z [Term] id: GO:0003357 name: noradrenergic neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." [GOC:dph] synonym: "norepinephrine secreting neuron differentiation" EXACT [GOC:dph] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008025 ! noradrenergic neuron relationship: results_in_acquisition_of_features_of CL:0008025 ! noradrenergic neuron created_by: dph creation_date: 2009-12-03T10:34:30Z [Term] id: GO:0003358 name: noradrenergic neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] synonym: "norepinephrine secreting neuron development" EXACT [GOC:dph] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0008025 ! noradrenergic neuron relationship: part_of GO:0003357 ! noradrenergic neuron differentiation relationship: results_in_development_of CL:0008025 ! noradrenergic neuron created_by: dph creation_date: 2009-12-03T10:38:37Z [Term] id: GO:0003360 name: brainstem development namespace: biological_process def: "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002298 ! brainstem relationship: results_in_development_of UBERON:0002298 ! brainstem created_by: dph creation_date: 2009-12-03T10:47:20Z [Term] id: GO:0003361 name: noradrenergic neuron differentiation involved in brainstem development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem." [GOC:dph] is_a: GO:0003357 ! noradrenergic neuron differentiation intersection_of: GO:0003357 ! noradrenergic neuron differentiation intersection_of: part_of GO:0003360 ! brainstem development relationship: part_of GO:0003360 ! brainstem development created_by: dph creation_date: 2009-12-03T10:53:30Z [Term] id: GO:0003365 name: establishment of cell polarity involved in ameboidal cell migration namespace: biological_process def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: part_of GO:0001667 ! ameboidal-type cell migration relationship: part_of GO:0001667 ! ameboidal-type cell migration created_by: dph creation_date: 2009-12-08T04:50:41Z [Term] id: GO:0003371 name: establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: part_of GO:0001667 ! ameboidal-type cell migration relationship: part_of GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration created_by: dph creation_date: 2009-12-08T05:42:46Z [Term] id: GO:0003379 name: establishment of cell polarity involved in gastrulation cell migration namespace: biological_process def: "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003365 ! establishment of cell polarity involved in ameboidal cell migration intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: part_of GO:0042074 ! cell migration involved in gastrulation relationship: part_of GO:0042074 ! cell migration involved in gastrulation created_by: dph creation_date: 2009-12-09T06:54:44Z [Term] id: GO:0003380 name: establishment or maintenance of cytoskeleton polarity involved in gastrulation namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003371 ! establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration intersection_of: GO:0030952 ! establishment or maintenance of cytoskeleton polarity intersection_of: part_of GO:0007369 ! gastrulation relationship: part_of GO:0003379 ! establishment of cell polarity involved in gastrulation cell migration created_by: dph creation_date: 2009-12-09T07:10:57Z [Term] id: GO:0003381 name: epithelial cell morphogenesis involved in gastrulation namespace: biological_process def: "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0003382 ! epithelial cell morphogenesis intersection_of: GO:0003382 ! epithelial cell morphogenesis intersection_of: part_of GO:0007369 ! gastrulation relationship: part_of GO:0007369 ! gastrulation created_by: dph creation_date: 2009-12-09T07:18:53Z [Term] id: GO:0003382 name: epithelial cell morphogenesis namespace: biological_process def: "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000904 ! cell morphogenesis involved in differentiation intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_maturation_of CL:0000066 ! epithelial cell relationship: part_of GO:0002064 ! epithelial cell development relationship: results_in_maturation_of CL:0000066 ! epithelial cell created_by: dph creation_date: 2009-12-09T07:21:06Z [Term] id: GO:0003403 name: optic vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0004128 ! optic vesicle relationship: part_of GO:0003404 ! optic vesicle morphogenesis relationship: part_of GO:0060900 ! embryonic camera-type eye formation relationship: results_in_formation_of UBERON:0004128 ! optic vesicle created_by: dph creation_date: 2009-12-21T01:42:37Z [Term] id: GO:0003404 name: optic vesicle morphogenesis namespace: biological_process def: "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004128 ! optic vesicle relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0004128 ! optic vesicle created_by: dph creation_date: 2009-12-21T01:54:34Z [Term] id: GO:0003407 name: neural retina development namespace: biological_process def: "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003902 ! retinal neural layer relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: results_in_development_of UBERON:0003902 ! retinal neural layer created_by: dph creation_date: 2009-12-21T02:15:14Z [Term] id: GO:0003411 name: cell motility involved in camera-type eye morphogenesis namespace: biological_process def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: part_of GO:0048593 ! camera-type eye morphogenesis relationship: part_of GO:0048593 ! camera-type eye morphogenesis created_by: dph creation_date: 2009-12-21T03:04:27Z [Term] id: GO:0003413 name: chondrocyte differentiation involved in endochondral bone morphogenesis namespace: biological_process def: "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002062 ! chondrocyte differentiation intersection_of: GO:0002062 ! chondrocyte differentiation intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0060351 ! cartilage development involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T08:39:58Z [Term] id: GO:0003414 name: chondrocyte morphogenesis involved in endochondral bone morphogenesis namespace: biological_process def: "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090171 ! chondrocyte morphogenesis intersection_of: GO:0090171 ! chondrocyte morphogenesis intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0003433 ! chondrocyte development involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T08:42:55Z [Term] id: GO:0003416 name: endochondral bone growth namespace: biological_process def: "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0002513 ! endochondral bone relationship: results_in_growth_of UBERON:0002513 ! endochondral bone created_by: dph creation_date: 2009-12-22T08:52:55Z [Term] id: GO:0003433 name: chondrocyte development involved in endochondral bone morphogenesis namespace: biological_process def: "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0002063 ! chondrocyte development intersection_of: GO:0002063 ! chondrocyte development intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis created_by: dph creation_date: 2009-12-22T12:42:44Z [Term] id: GO:0003674 name: molecular_function namespace: molecular_function alt_id: GO:0005554 def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." [GOC:pdt] def: "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." [GOC:pdt] comment: Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "molecular function" EXACT [] is_a: BFO:0000015 ! process is_a: http://rs.tdwg.org/dwc/terms/Event ! Event disjoint_from: GO:0005575 ! cellular_component disjoint_from: GO:0008150 ! biological_process property_value: IAO:0000589 "molecular process" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0003824 name: catalytic activity namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." [GOC:vw, ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "enzyme activity" EXACT [GOC:dph, GOC:tb] xref: Wikipedia:Enzyme is_a: GO:0003674 ! molecular_function property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0004518 name: nuclease activity namespace: molecular_function def: "Catalysis of the hydrolysis of ester linkages within nucleic acids." [ISBN:0198547684] comment: Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. subset: goslim_chembl subset: goslim_drosophila subset: goslim_plant subset: goslim_yeast is_a: GO:0016788 ! hydrolase activity, acting on ester bonds [Term] id: GO:0004536 name: DNA nuclease activity namespace: molecular_function alt_id: GO:0004537 def: "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah, ISBN:0198547684] synonym: "caspase-activated deoxyribonuclease activity" NARROW [] synonym: "deoxyribonuclease activity" EXACT [] xref: Reactome:R-HSA-211247 "Cleavage of DNA by DFF40" xref: Reactome:R-HSA-5685994 "Long-range resection of DNA DSBs by EXO1 or DNA2" xref: Reactome:R-HSA-6785986 "DNA nucleases unhook the interstrand crosslink (ICL)" is_a: GO:0004518 ! nuclease activity is_a: GO:0140097 ! catalytic activity, acting on DNA relationship: part_of GO:0006259 ! DNA metabolic process [Term] id: GO:0005215 name: transporter activity namespace: molecular_function alt_id: GO:0005478 def: "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." [GOC:ai, GOC:dgf] comment: Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules. subset: gocheck_do_not_annotate subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: prokaryote_subset synonym: "carrier" RELATED [] xref: Reactome:R-HSA-168313 "Virion-associated M2 protein mediated ion infusion" xref: Reactome:R-HSA-178215 "SMAD7:SMURF1 complex is exported to the cytosol" is_a: GO:0003674 ! molecular_function [Term] id: GO:0005275 name: amine transmembrane transporter activity namespace: molecular_function alt_id: GO:0005279 def: "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." [GOC:mtg_transport, ISBN:0198506732, ISBN:0815340729] synonym: "amine/amide/polyamine channel activity" BROAD [] synonym: "amine/polyamine transmembrane transporter activity" EXACT [] synonym: "amino acid-polyamine transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:32952 ! amine relationship: has_primary_input CHEBI:32952 ! amine relationship: part_of GO:0015837 ! amine transport [Term] id: GO:0005277 name: acetylcholine transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] xref: Reactome:R-HSA-264615 "Loading of acetylcholine in synaptic vesicles" is_a: GO:0005326 ! neurotransmitter transmembrane transporter activity is_a: GO:0015101 ! organic cation transmembrane transporter activity is_a: GO:1901375 ! acetate ester transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:15355 ! acetylcholine relationship: has_primary_input CHEBI:15355 ! acetylcholine [Term] id: GO:0005310 name: dicarboxylic acid transmembrane transporter activity namespace: molecular_function alt_id: GO:0005312 alt_id: GO:0015365 def: "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." [GOC:ai] synonym: "dicarboxylate (succinate/fumarate/malate) antiporter activity" RELATED [] synonym: "dicarboxylate carrier" NARROW [] synonym: "dicarboxylic acid permease activity" RELATED [] synonym: "sodium:dicarboxylate/tricarboxylate symporter activity" NARROW [] xref: Reactome:R-HSA-1614546 "Sulfate is exported to the cytosol in exchange for dicarboxylate" xref: Reactome:R-HSA-372843 "SLC25A10 mediates exchange of malate and phosphate" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:35692 ! dicarboxylic acid relationship: has_primary_input CHEBI:35692 ! dicarboxylic acid relationship: part_of GO:0006835 ! dicarboxylic acid transport [Term] id: GO:0005319 name: lipid transporter activity namespace: molecular_function def: "Enables the directed movement of lipids into, out of or within a cell, or between cells." [GOC:ai] synonym: "apolipoprotein" RELATED [] synonym: "lipophorin" NARROW [] xref: Reactome:R-HSA-1369028 "ABCAs mediate lipid efflux" xref: Reactome:R-HSA-1369052 "ABCAs mediate lipid influx" xref: Reactome:R-HSA-174786 "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex" xref: Reactome:R-HSA-5682285 "ABCA12 transports lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5682311 "Defective ABCA12 does not transport lipids from cytosol to extracellular region" xref: Reactome:R-HSA-5683672 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5683714 "ABCA3 transports PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-5688397 "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body" xref: Reactome:R-HSA-6801250 "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane" xref: Reactome:R-HSA-8848053 "ABCA5 transports CHOL from lysosomal lumen to cytosol" xref: Reactome:R-HSA-8866329 "MTTP lipidates APOB-100, forming a pre-VLDL" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid relationship: part_of GO:0006869 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! lipid transport [Term] id: GO:0005326 name: neurotransmitter transmembrane transporter activity namespace: molecular_function def: "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai, ISBN:0198506732] synonym: "neurotransmitter transporter activity" RELATED [] xref: Reactome:R-HSA-374896 "Uptake of Noradrenaline" xref: Reactome:R-HSA-374919 "Noradrenaline clearance from the synaptic cleft" relationship: part_of GO:0006836 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! neurotransmitter transport [Term] id: GO:0005342 name: organic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:64709 ! organic acid relationship: has_primary_input CHEBI:64709 ! organic acid relationship: part_of GO:1903825 ! organic acid transmembrane transport [Term] id: GO:0005355 name: glucose transmembrane transporter activity namespace: molecular_function alt_id: GO:0015579 def: "Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "galactose/glucose (methylgalactoside) porter activity" RELATED [] synonym: "glucose permease activity" EXACT [] synonym: "lactose/glucose efflux transporter activity" NARROW [] xref: Reactome:R-HSA-499981 "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2" xref: Reactome:R-HSA-5653873 "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen" is_a: GO:0015149 ! hexose transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17234 ! glucose relationship: has_primary_input CHEBI:17234 ! glucose relationship: part_of GO:1904659 ! glucose transmembrane transport [Term] id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 def: "A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome)." [GOC:pdt, NIF_Subcellular:sao1337158144] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell or subcellular entity" EXACT [] synonym: "cellular component" EXACT [] synonym: "subcellular entity" RELATED [NIF_Subcellular:nlx_subcell_100315] xref: NIF_Subcellular:sao1337158144 is_a: BFO:0000040 ! material entity disjoint_from: GO:0008150 ! biological_process [Term] id: GO:0005576 name: extracellular region namespace: cellular_component def: "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." [GOC:go_curators] comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: prokaryote_subset synonym: "extracellular" EXACT [] xref: Wikipedia:Extracellular is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0005577 name: fibrinogen complex namespace: cellular_component def: "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." [ISBN:0198547684] synonym: "fibrinogen" EXACT [] synonym: "fibrinogen alpha chain" NARROW [] synonym: "fibrinogen beta chain" NARROW [] synonym: "fibrinogen gamma chain" NARROW [] is_a: GO:0032991 ! protein-containing complex relationship: part_of GO:0005615 ! extracellular space [Term] id: GO:0005581 name: collagen trimer namespace: cellular_component def: "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." [GOC:dos, GOC:mah, ISBN:0721639976, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen is_a: GO:0032991 ! protein-containing complex relationship: in_taxon NCBITaxon:33208 {all_only="true", source="PMID:12382326"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 {source="PMID:12382326"} ! Metazoa [Term] id: GO:0005583 name: fibrillar collagen trimer namespace: cellular_component def: "Any triple helical collagen trimer that forms fibrils." [GOC:mah, ISBN:0721639976, PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0098643 ! banded collagen fibril disjoint_from: GO:0030936 ! transmembrane collagen trimer relationship: part_of GO:0098643 ! banded collagen fibril [Term] id: GO:0005585 name: collagen type II trimer namespace: cellular_component def: "A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils." [ISBN:0721639976] xref: Wikipedia:Collagen_type_II is_a: GO:0005583 ! fibrillar collagen trimer [Term] id: GO:0005587 name: collagen type IV trimer namespace: cellular_component def: "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." [ISBN:0721639976, PMID:19693541, PMID:21421911] xref: Wikipedia:Collagen_type_IV is_a: GO:0098642 ! network-forming collagen trimer is_a: GO:0098651 ! basement membrane collagen trimer [Term] id: GO:0005604 name: basement membrane namespace: cellular_component alt_id: GO:0005605 alt_id: GO:0008003 def: "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." [ISBN:0198547684, PMID:22505934] comment: Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer. synonym: "basal lamina" RELATED [] synonym: "basement lamina" RELATED [] synonym: "lamina densa" RELATED [] xref: Wikipedia:Basement_membrane is_a: GO:0062023 ! collagen-containing extracellular matrix [Term] id: GO:0005615 name: extracellular space namespace: cellular_component def: "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." [ISBN:0198547684] comment: Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: prokaryote_subset synonym: "intercellular space" RELATED [] xref: NIF_Subcellular:sao1425028079 is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005576 ! extracellular region [Term] id: GO:0005622 name: intracellular anatomical structure namespace: cellular_component def: "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." [ISBN:0198506732] subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "internal to cell" EXACT [] synonym: "intracellular" EXACT [] synonym: "nucleocytoplasm" RELATED [GOC:mah] synonym: "protoplasm" EXACT [] synonym: "protoplast" RELATED [GOC:mah] xref: Wikipedia:Intracellular is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17776" xsd:anyURI [Term] id: GO:0005634 name: nucleus namespace: cellular_component def: "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." [GOC:go_curators] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "cell nucleus" EXACT [] synonym: "horsetail nucleus" NARROW [GOC:al, GOC:mah, GOC:vw, PMID:15030757] xref: NIF_Subcellular:sao1702920020 xref: Wikipedia:Cell_nucleus is_a: GO:0043231 ! intracellular membrane-bounded organelle disjoint_from: GO:0005737 ! cytoplasm relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0005635 name: nuclear envelope namespace: cellular_component alt_id: GO:0005636 def: "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." [ISBN:0198547684] subset: goslim_chembl subset: goslim_generic subset: goslim_plant xref: Wikipedia:Nuclear_envelope is_a: GO:0031967 ! organelle envelope relationship: part_of GO:0005634 ! nucleus relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0005640 name: nuclear outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." [ISBN:0198547684] synonym: "nucleus outer envelope" EXACT [] synonym: "perinuclear membrane" EXACT [] xref: NIF_Subcellular:sao1617136075 is_a: GO:0031965 ! nuclear membrane is_a: GO:0031968 ! organelle outer membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005634 ! nucleus relationship: bounding_layer_of GO:0005634 ! nucleus relationship: part_of GO:0042175 ! nuclear outer membrane-endoplasmic reticulum membrane network [Term] id: GO:0005694 name: chromosome namespace: cellular_component def: "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." [ISBN:0198547684] comment: Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_yeast subset: prokaryote_subset synonym: "chromatid" RELATED [] synonym: "interphase chromosome" NARROW [] synonym: "prophase chromosome" NARROW [] xref: Wikipedia:Chromosome is_a: GO:0043232 ! intracellular non-membrane-bounded organelle [Term] id: GO:0005730 name: nucleolus namespace: cellular_component def: "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast xref: NIF_Subcellular:sao1820400233 xref: Wikipedia:Nucleolus is_a: GO:0043232 ! intracellular non-membrane-bounded organelle relationship: part_of GO:0031981 ! nuclear lumen [Term] id: GO:0005737 name: cytoplasm namespace: cellular_component def: "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [ISBN:0198547684] subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: prokaryote_subset xref: Wikipedia:Cytoplasm is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005622 ! intracellular anatomical structure property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23023" xsd:anyURI [Term] id: GO:0005773 name: vacuole namespace: cellular_component def: "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." [GOC:mtg_sensu, ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "vacuolar carboxypeptidase Y" RELATED [] xref: Wikipedia:Vacuole is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005774 name: vacuolar membrane namespace: cellular_component def: "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." [GOC:ai] is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005773 ! vacuole relationship: bounding_layer_of GO:0005773 ! vacuole relationship: part_of GO:0005773 ! vacuole [Term] id: GO:0005775 name: vacuolar lumen namespace: cellular_component def: "The volume enclosed within the vacuolar membrane." [ISBN:0198506732] is_a: GO:0070013 ! intracellular organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0005773 ! vacuole relationship: part_of GO:0005773 ! vacuole [Term] id: GO:0005794 name: Golgi apparatus namespace: cellular_component def: "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." [ISBN:0198506732] comment: Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon. subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "Golgi" BROAD [] synonym: "Golgi complex" EXACT [] synonym: "Golgi ribbon" NARROW [] xref: NIF_Subcellular:sao451912436 xref: Wikipedia:Golgi_apparatus is_a: GO:0043231 ! intracellular membrane-bounded organelle relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0005798 name: Golgi-associated vesicle namespace: cellular_component def: "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." [GOC:mah] comment: Note that this definition includes vesicles that are transiently associated with the Golgi. synonym: "Golgi vesicle" RELATED [] synonym: "vesicular component" RELATED [NIF_Subcellular:sao138219748] xref: NIF_Subcellular:sao819927218 is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0005840 name: ribosome namespace: cellular_component alt_id: GO:0033279 def: "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: prokaryote_subset synonym: "free ribosome" NARROW [NIF_Subcellular:sao1139385046] synonym: "membrane bound ribosome" NARROW [NIF_Subcellular:sao1291545653] synonym: "ribosomal RNA" RELATED [] xref: NIF_Subcellular:sao1429207766 xref: Wikipedia:Ribosome is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: PR:000050567 ! protein-containing material entity relationship: capable_of_part_of GO:0006412 ! translation relationship: has_part CHEBI:33697 ! ribonucleic acid [Term] id: GO:0005856 name: cytoskeleton namespace: cellular_component def: "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." [GOC:mah, PMID:16959967, PMID:27419875] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: prokaryote_subset xref: Wikipedia:Cytoskeleton is_a: GO:0043232 ! intracellular non-membrane-bounded organelle [Term] id: GO:0005874 name: microtubule namespace: cellular_component def: "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." [ISBN:0879693568] subset: goslim_metagenomics synonym: "microtubuli" EXACT [] synonym: "microtubulus" EXACT [] synonym: "neurotubule" NARROW [NIF_Subcellular:sao248349196] xref: NIF_Subcellular:sao1846835077 xref: Wikipedia:Microtubule is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0015630 ! microtubule cytoskeleton [Term] id: GO:0005879 name: axonemal microtubule namespace: cellular_component def: "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." [GOC:cilia, ISBN:0815316194] is_a: GO:0005881 ! cytoplasmic microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005930 ! axoneme relationship: part_of GO:0005930 ! axoneme [Term] id: GO:0005880 name: nuclear microtubule namespace: cellular_component def: "Any microtubule in the nucleus of a cell." [GOC:mah] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0005634 ! nucleus [Term] id: GO:0005881 name: cytoplasmic microtubule namespace: cellular_component def: "Any microtubule in the cytoplasm of a cell." [GOC:mah] synonym: "non-spindle-associated astral microtubule" NARROW [] is_a: GO:0005874 ! microtubule intersection_of: GO:0005874 ! microtubule intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0005882 name: intermediate filament namespace: cellular_component def: "A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins." [http://www.cytochemistry.net/Cell-biology/intermediate_filaments.htm, ISBN:0198506732] synonym: "intermediate filament associated protein" RELATED [] synonym: "type I intermediate filament associated protein" RELATED [] synonym: "type II intermediate filament associated protein" RELATED [] xref: FMA:63851 xref: NIF_Subcellular:sao952483289 xref: Wikipedia:Intermediate_filament is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0045111 ! intermediate filament cytoskeleton [Term] id: GO:0005884 name: actin filament namespace: cellular_component def: "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." [GOC:mah, ISBN:0198506732, PMID:10666339] synonym: "microfilament" EXACT [] xref: FMA:63850 xref: NIF_Subcellular:sao1588493326 xref: Wikipedia:Actin is_a: GO:0099513 ! polymeric cytoskeletal fiber relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0005886 name: plasma membrane namespace: cellular_component alt_id: GO:0005887 alt_id: GO:0005904 def: "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." [ISBN:0716731363] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_plant subset: goslim_yeast subset: prokaryote_subset synonym: "bacterial inner membrane" NARROW [] synonym: "cell membrane" EXACT [] synonym: "cellular membrane" EXACT [NIF_Subcellular:sao6433132645] synonym: "cytoplasmic membrane" EXACT [] synonym: "inner endospore membrane" NARROW [] synonym: "integral component of plasma membrane" NARROW [] synonym: "integral to plasma membrane" NARROW [] synonym: "juxtamembrane" BROAD [] synonym: "plasma membrane lipid bilayer" NARROW [GOC:mah] synonym: "plasmalemma" EXACT [] xref: NIF_Subcellular:sao1663586795 xref: Wikipedia:Cell_membrane is_a: GO:0016020 ! membrane relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0005902 name: microvillus namespace: cellular_component def: "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." [ISBN:0815316194] comment: Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta. subset: goslim_pir synonym: "microvilli" RELATED [NIF_Subcellular:sao671419673] xref: NIF_Subcellular:sao671419673 xref: Wikipedia:Microvillus is_a: GO:0098858 ! actin-based cell projection relationship: has_part GO:0032432 ! actin filament bundle relationship: part_of CL:0000066 ! epithelial cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0005911 name: cell-cell junction namespace: cellular_component def: "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." [GOC:aruk, GOC:bc, GOC:dgh, GOC:hb, GOC:mah, PMID:21422226, PMID:28096264] synonym: "cell-cell contact region" BROAD [] synonym: "cell-cell contact zone" BROAD [] synonym: "intercellular junction" EXACT [NIF_Subcellular:sao1395777368] xref: NIF_Subcellular:sao1922892319 is_a: GO:0070161 ! anchoring junction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22122" xsd:anyURI [Term] id: GO:0005929 name: cilium namespace: cellular_component alt_id: GO:0072372 def: "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." [GOC:cilia, GOC:curators, GOC:kmv, GOC:vw, ISBN:0198547684, PMID:16824949, PMID:17009929, PMID:20144998] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir synonym: "eukaryotic flagellum" EXACT [] synonym: "flagellum" RELATED [] synonym: "microtubule-based flagellum" EXACT [] synonym: "primary cilium" NARROW [] xref: FMA:67181 xref: NIF_Subcellular:sao787716553 xref: Wikipedia:Cilium is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0120025 ! plasma membrane bounded cell projection is_a: PR:000050567 ! protein-containing material entity relationship: has_part GO:0030990 ! intraciliary transport particle relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0005930 name: axoneme namespace: cellular_component alt_id: GO:0035085 alt_id: GO:0035086 def: "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, ISBN:0198547684] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane. subset: goslim_pir synonym: "ciliary axoneme" EXACT [] synonym: "cilium axoneme" EXACT [] synonym: "flagellar axoneme" EXACT [] synonym: "flagellum axoneme" EXACT [] xref: Wikipedia:Axoneme is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005874 ! microtubule relationship: part_of GO:0005856 ! cytoskeleton relationship: part_of GO:0097014 ! ciliary plasm [Term] id: GO:0005938 name: cell cortex namespace: cellular_component def: "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." [GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_yeast synonym: "cell periphery" RELATED [] synonym: "peripheral cytoplasm" RELATED [] xref: Wikipedia:Cell_cortex is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0071944 ! cell periphery relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0005975 name: carbohydrate metabolic process namespace: biological_process alt_id: GO:0044261 alt_id: GO:0044723 def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [GOC:mah, ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast subset: prokaryote_subset synonym: "carbohydrate metabolism" EXACT [] xref: Wikipedia:Carbohydrate_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16646 ! carbohydrate relationship: has_primary_input_or_output CHEBI:16646 ! carbohydrate property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22880" xsd:anyURI created_by: jl creation_date: 2012-10-23T15:40:34Z [Term] id: GO:0005976 name: polysaccharide metabolic process namespace: biological_process alt_id: GO:0044263 def: "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [ISBN:0198547684] subset: goslim_pir synonym: "glycan metabolic process" NARROW [] synonym: "glycan metabolism" NARROW [] synonym: "multicellular organismal polysaccharide metabolic process" NARROW [] synonym: "polysaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18154 ! polysaccharide relationship: has_primary_input_or_output CHEBI:18154 ! polysaccharide [Term] id: GO:0005977 name: glycogen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." [ISBN:0198506732] synonym: "glycogen metabolism" EXACT [] is_a: GO:0006112 ! energy reserve metabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:28087 ! glycogen relationship: has_primary_input_or_output CHEBI:28087 ! glycogen [Term] id: GO:0005978 name: glycogen biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen anabolism" EXACT [] synonym: "glycogen biosynthesis" EXACT [] synonym: "glycogen formation" EXACT [] synonym: "glycogen synthesis" EXACT [] xref: MetaCyc:GLYCOGENSYNTH-PWY is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009250 ! glucan biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:28087 ! glycogen relationship: has_primary_output CHEBI:28087 ! glycogen [Term] id: GO:0005979 name: regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "regulation of glycogen anabolism" EXACT [] synonym: "regulation of glycogen biosynthesis" EXACT [] synonym: "regulation of glycogen formation" EXACT [] synonym: "regulation of glycogen synthesis" EXACT [] is_a: GO:0010962 ! regulation of glucan biosynthetic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005978 ! glycogen biosynthetic process relationship: regulates GO:0005978 ! glycogen biosynthetic process [Term] id: GO:0005980 name: glycogen catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." [ISBN:0198506732] synonym: "glycogen breakdown" EXACT [] synonym: "glycogen catabolism" EXACT [] synonym: "glycogen degradation" EXACT [] synonym: "glycogenolysis" EXACT [GOC:sl] xref: MetaCyc:GLYCOCAT-PWY is_a: GO:0005977 ! glycogen metabolic process is_a: GO:0009251 ! glucan catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:28087 ! glycogen relationship: has_primary_input CHEBI:28087 ! glycogen [Term] id: GO:0005981 name: regulation of glycogen catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "regulation of glycogen breakdown" EXACT [] synonym: "regulation of glycogen catabolism" EXACT [] synonym: "regulation of glycogen degradation" EXACT [] synonym: "regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0043470 ! regulation of carbohydrate catabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005980 ! glycogen catabolic process relationship: regulates GO:0005980 ! glycogen catabolic process [Term] id: GO:0005996 name: monosaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [ISBN:0198506732] synonym: "monosaccharide metabolism" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:0044281 ! small molecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35381 ! monosaccharide relationship: has_primary_input_or_output CHEBI:35381 ! monosaccharide [Term] id: GO:0006006 name: glucose metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." [ISBN:0198506732] synonym: "cellular glucose metabolic process" EXACT [GOC:vw] synonym: "glucose metabolism" EXACT [] is_a: GO:0019318 ! hexose metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:17234 ! glucose relationship: has_primary_input_or_output CHEBI:17234 ! glucose [Term] id: GO:0006007 name: glucose catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose." [GOC:ai] synonym: "glucose breakdown" EXACT [] synonym: "glucose catabolism" EXACT [] synonym: "glucose degradation" EXACT [] is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019320 ! hexose catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:17234 ! glucose relationship: has_primary_input CHEBI:17234 ! glucose [Term] id: GO:0006022 name: aminoglycan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan metabolism" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:22506 ! aminoglycan relationship: has_primary_input_or_output CHEBI:22506 ! aminoglycan [Term] id: GO:0006023 name: aminoglycan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan anabolism" EXACT [] synonym: "aminoglycan biosynthesis" EXACT [] synonym: "aminoglycan formation" EXACT [] synonym: "aminoglycan synthesis" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:22506 ! aminoglycan relationship: has_primary_output CHEBI:22506 ! aminoglycan [Term] id: GO:0006024 name: glycosaminoglycan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan anabolism" EXACT [] synonym: "glycosaminoglycan biosynthesis" EXACT [] synonym: "glycosaminoglycan formation" EXACT [] synonym: "glycosaminoglycan synthesis" EXACT [] is_a: GO:0006023 ! aminoglycan biosynthetic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18085 ! glycosaminoglycan relationship: has_primary_output CHEBI:18085 ! glycosaminoglycan [Term] id: GO:0006026 name: aminoglycan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." [GOC:ai, ISBN:0198506732] synonym: "aminoglycan breakdown" EXACT [] synonym: "aminoglycan catabolism" EXACT [] synonym: "aminoglycan degradation" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:22506 ! aminoglycan relationship: has_primary_input CHEBI:22506 ! aminoglycan [Term] id: GO:0006027 name: glycosaminoglycan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan breakdown" EXACT [] synonym: "glycosaminoglycan catabolism" EXACT [] synonym: "glycosaminoglycan degradation" EXACT [] is_a: GO:0006026 ! aminoglycan catabolic process is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18085 ! glycosaminoglycan relationship: has_primary_input CHEBI:18085 ! glycosaminoglycan [Term] id: GO:0006082 name: organic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] subset: goslim_pir synonym: "organic acid metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:64709 ! organic acid relationship: has_primary_input_or_output CHEBI:64709 ! organic acid [Term] id: GO:0006083 name: acetate metabolic process namespace: biological_process def: "The chemical reactions and pathways involving acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate metabolism" EXACT [] is_a: GO:0032787 ! monocarboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:30089 ! acetate relationship: has_primary_input_or_output CHEBI:30089 ! acetate [Term] id: GO:0006091 name: generation of precursor metabolites and energy namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." [GOC:jl] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast subset: prokaryote_subset synonym: "energy pathways" BROAD [] synonym: "intermediary metabolism" RELATED [GOC:mah] synonym: "metabolic energy generation" RELATED [] is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0006094 name: gluconeogenesis namespace: biological_process def: "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [MetaCyc:GLUCONEO-PWY] synonym: "glucose biosynthesis" EXACT [] synonym: "glucose biosynthetic process" EXACT [] xref: MetaCyc:GLUCONEO-PWY xref: Wikipedia:Gluconeogenesis is_a: GO:0006006 ! glucose metabolic process is_a: GO:0019319 ! hexose biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:17234 ! glucose relationship: has_primary_output CHEBI:17234 ! glucose [Term] id: GO:0006109 name: regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." [GOC:go_curators] synonym: "regulation of carbohydrate metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005975 ! carbohydrate metabolic process relationship: regulates GO:0005975 ! carbohydrate metabolic process [Term] id: GO:0006111 name: regulation of gluconeogenesis namespace: biological_process alt_id: GO:0090526 def: "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." [GOC:go_curators] synonym: "regulation of gluconeogenesis involved in cellular glucose homeostasis" RELATED [] synonym: "regulation of glucose biosynthesis" BROAD [] synonym: "regulation of glucose biosynthetic process" BROAD [] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006094 ! gluconeogenesis relationship: regulates GO:0006094 ! gluconeogenesis created_by: tb creation_date: 2013-01-18T12:47:43Z [Term] id: GO:0006112 name: energy reserve metabolic process namespace: biological_process def: "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen." [GOC:mah] subset: goslim_pir synonym: "energy reserve metabolism" EXACT [] is_a: GO:0015980 ! energy derivation by oxidation of organic compounds [Term] id: GO:0006139 name: nucleobase-containing compound metabolic process namespace: biological_process alt_id: GO:0055134 def: "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:ai] subset: goslim_pir subset: goslim_plant synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044238 ! primary metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input_or_output CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0006259 name: DNA metabolic process namespace: biological_process alt_id: GO:0055132 def: "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." [ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "cellular DNA metabolism" EXACT [] synonym: "DNA metabolism" EXACT [] is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_input_or_output CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0006308 name: DNA catabolic process namespace: biological_process def: "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." [GOC:go_curators, ISBN:0198506732] synonym: "DNA breakdown" EXACT [] synonym: "DNA catabolism" EXACT [] synonym: "DNA degradation" EXACT [] is_a: GO:0006259 ! DNA metabolic process is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0034655 ! nucleobase-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_part GO:0004536 ! DNA nuclease activity relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0006309 name: apoptotic DNA fragmentation namespace: biological_process alt_id: GO:0008178 def: "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976, PMID:15723341, PMID:23379520] comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341). synonym: "chromatinolysis" BROAD [GOC:mtg_apoptosis] synonym: "DNA catabolic process during apoptosis" EXACT [] synonym: "DNA catabolism during apoptosis" EXACT [] synonym: "DNA fragmentation" BROAD [] synonym: "DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:cjm, GOC:dph, GOC:tb] synonym: "endonucleolytic DNA catabolic process involved in apoptosis" EXACT [] is_a: GO:0006308 ! DNA catabolic process intersection_of: GO:0006308 ! DNA catabolic process intersection_of: part_of GO:0030262 ! apoptotic nuclear changes relationship: part_of GO:0030262 ! apoptotic nuclear changes property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24396" xsd:anyURI [Term] id: GO:0006325 name: chromatin organization namespace: biological_process alt_id: GO:0006333 alt_id: GO:0006336 alt_id: GO:0016568 alt_id: GO:0031497 alt_id: GO:0034724 def: "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." [PMID:20404130] subset: goslim_generic subset: goslim_pombe subset: goslim_yeast synonym: "chromatin assembly" NARROW [] synonym: "chromatin assembly or disassembly" RELATED [] synonym: "chromatin assembly/disassembly" RELATED [] synonym: "chromatin maintenance" BROAD [] synonym: "chromatin modification" RELATED [] synonym: "chromatin organisation" EXACT [GOC:mah] synonym: "DNA replication-independent chromatin assembly" NARROW [] synonym: "DNA replication-independent chromatin organization" NARROW [] synonym: "DNA replication-independent nucleosome organisation" NARROW [] synonym: "DNA replication-independent nuclesome assembly" NARROW [] synonym: "establishment of chromatin architecture" EXACT [GOC:mah] synonym: "establishment or maintenance of chromatin architecture" EXACT [GOC:mah] synonym: "transcription-coupled nucleosome assembly" NARROW [] is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0000785 ! chromatin relationship: results_in_organization_of GO:0000785 ! chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22130" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23549" xsd:anyURI [Term] id: GO:0006401 name: RNA catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] subset: goslim_yeast synonym: "RNA breakdown" EXACT [] synonym: "RNA catabolism" EXACT [] synonym: "RNA degradation" EXACT [] is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0016070 ! RNA metabolic process is_a: GO:0034655 ! nucleobase-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: has_primary_input CHEBI:33697 ! ribonucleic acid [Term] id: GO:0006403 name: RNA localization namespace: biological_process def: "A process in which RNA is transported to, or maintained in, a specific location." [GOC:ai] subset: goslim_drosophila synonym: "establishment and maintenance of RNA localization" EXACT [] synonym: "RNA localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization [Term] id: GO:0006412 name: translation namespace: biological_process alt_id: GO:0006416 alt_id: GO:0006453 alt_id: GO:0043037 def: "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." [GOC:go_curators] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: prokaryote_subset synonym: "protein anabolism" EXACT [] synonym: "protein biosynthesis" EXACT [] synonym: "protein biosynthetic process" EXACT [] synonym: "protein formation" EXACT [] synonym: "protein synthesis" EXACT [] synonym: "protein translation" EXACT [] xref: Wikipedia:Translation_(genetics) is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0019538 ! protein metabolic process is_a: GO:0043043 ! peptide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16541 ! protein polypeptide chain intersection_of: part_of GO:0010467 ! gene expression relationship: ends_with GO:0006415 ! translational termination relationship: has_part GO:0006414 ! translational elongation relationship: has_primary_output CHEBI:16541 ! protein polypeptide chain relationship: part_of GO:0010467 ! gene expression relationship: starts_with GO:0006413 ! translational initiation [Term] id: GO:0006413 name: translational initiation namespace: biological_process alt_id: GO:0006440 alt_id: GO:0006454 def: "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." [ISBN:019879276X] subset: goslim_yeast synonym: "biopolymerisation" BROAD [] synonym: "biopolymerization" BROAD [] synonym: "protein synthesis initiation" BROAD [] synonym: "translation initiation" EXACT [] is_a: GO:0044237 ! cellular metabolic process relationship: part_of GO:0006412 ! translation relationship: starts_with GO:0001677 ! formation of translation initiation ternary complex [Term] id: GO:0006414 name: translational elongation namespace: biological_process alt_id: GO:0006442 alt_id: GO:0006455 def: "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." [GOC:ems] subset: goslim_yeast synonym: "protein synthesis elongation" BROAD [] synonym: "translation elongation" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process relationship: part_of GO:0006412 ! translation [Term] id: GO:0006415 name: translational termination namespace: biological_process alt_id: GO:0006443 alt_id: GO:0006456 def: "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." [GOC:hjd, ISBN:019879276X] synonym: "protein synthesis termination" BROAD [] synonym: "translation termination" EXACT [] synonym: "translational complex disassembly" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly relationship: part_of GO:0006412 ! translation [Term] id: GO:0006417 name: regulation of translation namespace: biological_process alt_id: GO:0006445 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] subset: goslim_yeast synonym: "regulation of protein anabolism" EXACT [] synonym: "regulation of protein biosynthesis" EXACT [] synonym: "regulation of protein formation" EXACT [] synonym: "regulation of protein synthesis" EXACT [] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010608 ! post-transcriptional regulation of gene expression is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006412 ! translation relationship: regulates GO:0006412 ! translation [Term] id: GO:0006446 name: regulation of translational initiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational initiation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006413 ! translational initiation relationship: regulates GO:0006413 ! translational initiation [Term] id: GO:0006448 name: regulation of translational elongation namespace: biological_process def: "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006414 ! translational elongation relationship: regulates GO:0006414 ! translational elongation [Term] id: GO:0006449 name: regulation of translational termination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translational termination." [GOC:go_curators] is_a: GO:0006417 ! regulation of translation is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006415 ! translational termination relationship: regulates GO:0006415 ! translational termination [Term] id: GO:0006516 name: glycoprotein catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein breakdown" EXACT [] synonym: "glycoprotein catabolism" EXACT [] synonym: "glycoprotein degradation" EXACT [] is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:0030163 ! protein catabolic process is_a: GO:1901136 ! carbohydrate derivative catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:17089 ! glycoprotein relationship: has_primary_input CHEBI:17089 ! glycoprotein [Term] id: GO:0006518 name: peptide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:go_curators] subset: goslim_pir synonym: "peptide metabolism" EXACT [] is_a: GO:0043603 ! amide metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16670 ! peptide relationship: has_primary_input_or_output CHEBI:16670 ! peptide [Term] id: GO:0006520 name: amino acid metabolic process namespace: biological_process alt_id: GO:0006519 def: "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." [ISBN:0198506732] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: prokaryote_subset synonym: "amino acid and derivative metabolism" RELATED [] synonym: "cellular amino acid and derivative metabolic process" RELATED [] synonym: "cellular amino acid metabolic process" EXACT [] synonym: "cellular amino acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process is_a: GO:0044238 ! primary metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:37022 ! amino-acid anion relationship: has_primary_input_or_output CHEBI:37022 ! amino-acid anion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0006521 name: regulation of cellular amino acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." [GOC:go_curators] synonym: "regulation of amino acid metabolism" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006520 ! amino acid metabolic process relationship: regulates GO:0006520 ! amino acid metabolic process [Term] id: GO:0006576 name: biogenic amine metabolic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine metabolism" EXACT [] synonym: "cellular biogenic amine metabolic process" EXACT [] is_a: GO:0009308 ! amine metabolic process [Term] id: GO:0006581 name: acetylcholine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine breakdown" EXACT [] synonym: "acetylcholine catabolism" EXACT [] synonym: "acetylcholine degradation" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:0042135 ! neurotransmitter catabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:15355 ! acetylcholine relationship: has_primary_input CHEBI:15355 ! acetylcholine [Term] id: GO:0006584 name: catecholamine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine metabolism" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009712 ! catechol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33567 ! catecholamine relationship: has_primary_input_or_output CHEBI:33567 ! catecholamine [Term] id: GO:0006586 name: indolalkylamine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] synonym: "indolalkylamine metabolism" EXACT [] synonym: "indolamine metabolic process" BROAD [] synonym: "indolamine metabolism" BROAD [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0042430 ! indole-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole relationship: has_primary_input_or_output CHEBI:38631 ! aminoalkylindole [Term] id: GO:0006629 name: lipid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." [GOC:ma] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast subset: prokaryote_subset synonym: "lipid metabolism" EXACT [] xref: Wikipedia:Lipid_metabolism is_a: GO:0044238 ! primary metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18059 ! lipid relationship: has_primary_input_or_output CHEBI:18059 ! lipid [Term] id: GO:0006694 name: steroid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." [GOC:go_curators] synonym: "steroid anabolism" EXACT [] synonym: "steroid biosynthesis" EXACT [] synonym: "steroid formation" EXACT [] synonym: "steroid synthesis" EXACT [] synonym: "steroidogenesis" EXACT [] xref: Wikipedia:Steroid_metabolisms#Steroid_biosynthesis is_a: GO:0008202 ! steroid metabolic process is_a: GO:0008610 ! lipid biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35341 ! steroid relationship: has_primary_output CHEBI:35341 ! steroid [Term] id: GO:0006699 name: bile acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid anabolism" EXACT [] synonym: "bile acid biosynthesis" EXACT [] synonym: "bile acid formation" EXACT [] synonym: "bile acid synthesis" EXACT [] is_a: GO:0006694 ! steroid biosynthetic process is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:36235 ! bile acid anion relationship: has_primary_output CHEBI:36235 ! bile acid anion [Term] id: GO:0006706 name: steroid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:go_curators] synonym: "steroid breakdown" EXACT [] synonym: "steroid catabolism" EXACT [] synonym: "steroid degradation" EXACT [] is_a: GO:0008202 ! steroid metabolic process is_a: GO:0016042 ! lipid catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35341 ! steroid relationship: has_primary_input CHEBI:35341 ! steroid [Term] id: GO:0006725 name: cellular aromatic compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." [GOC:ai, ISBN:0198506732] subset: goslim_pir synonym: "aromatic compound metabolism" EXACT [] synonym: "aromatic hydrocarbon metabolic process" NARROW [] synonym: "aromatic hydrocarbon metabolism" NARROW [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33655 ! aromatic compound relationship: has_primary_input_or_output CHEBI:33655 ! aromatic compound [Term] id: GO:0006790 name: sulfur compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:ai] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: prokaryote_subset synonym: "sulfur metabolism" EXACT [] synonym: "sulphur metabolic process" EXACT [] synonym: "sulphur metabolism" EXACT [] xref: Wikipedia:Sulfur_metabolism is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input_or_output CHEBI:26835 ! sulfur molecular entity [Term] id: GO:0006793 name: phosphorus metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." [GOC:ai] subset: goslim_pir synonym: "phosphorus metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity relationship: has_primary_input_or_output CHEBI:26082 ! phosphorus molecular entity [Term] id: GO:0006796 name: phosphate-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." [GOC:ai] synonym: "phosphate metabolic process" RELATED [] synonym: "phosphate metabolism" EXACT [] is_a: GO:0006793 ! phosphorus metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26020 ! phosphate relationship: has_primary_input_or_output CHEBI:26020 ! phosphate [Term] id: GO:0006807 name: nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." [GOC:jl, ISBN:0198506732] subset: goslim_metagenomics subset: goslim_pir synonym: "nitrogen compound metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity relationship: has_primary_input_or_output CHEBI:51143 ! nitrogen molecular entity [Term] id: GO:0006810 name: transport namespace: biological_process alt_id: GO:0015457 alt_id: GO:0015460 alt_id: GO:0044765 def: "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." [GOC:dos, GOC:dph, GOC:jl, GOC:mah] comment: Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: prokaryote_subset synonym: "single-organism transport" RELATED [] is_a: GO:0051234 ! establishment of localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20292" xsd:anyURI created_by: jl creation_date: 2012-12-13T16:25:32Z [Term] id: GO:0006811 name: monoatomic ion transport namespace: biological_process def: "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:ai] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "ion transport" BROAD [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion relationship: has_primary_input CHEBI:24867 ! monoatomic ion [Term] id: GO:0006812 name: monoatomic cation transport namespace: biological_process alt_id: GO:0006819 alt_id: GO:0015674 alt_id: GO:0072512 def: "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:ai] synonym: "cation transport" BROAD [] synonym: "di-, tri-valent inorganic cation transport" NARROW [GOC:mah] synonym: "trivalent inorganic cation transport" NARROW [] is_a: GO:0006811 ! monoatomic ion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation relationship: has_primary_input CHEBI:23906 ! monoatomic cation [Term] id: GO:0006814 name: sodium ion transport namespace: biological_process alt_id: GO:0006834 alt_id: GO:0016974 def: "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "mitochondrial sodium/calcium ion exchange" NARROW [] synonym: "sodium channel auxiliary protein activity" RELATED [GOC:mah] synonym: "sodium transport" EXACT [] synonym: "sodium/potassium transport" BROAD [] synonym: "sodium:calcium exchange" NARROW [] synonym: "sodium:solute transport" NARROW [] is_a: GO:0030001 ! metal ion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) relationship: has_primary_input CHEBI:29101 ! sodium(1+) [Term] id: GO:0006817 name: phosphate ion transport namespace: biological_process def: "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "phosphate transport" RELATED [] is_a: GO:0015698 ! inorganic anion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35780 ! phosphate ion relationship: has_primary_input CHEBI:35780 ! phosphate ion [Term] id: GO:0006835 name: dicarboxylic acid transport namespace: biological_process alt_id: GO:0006841 def: "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "sodium:dicarboxylate transport" RELATED [] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0006836 name: neurotransmitter transport namespace: biological_process def: "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." [GOC:ai] subset: goslim_pir synonym: "sodium:neurotransmitter transport" NARROW [] is_a: GO:0006810 ! transport relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0006837 name: serotonin transport namespace: biological_process def: "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." [GOC:ai] is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) relationship: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0006846 name: acetate transport namespace: biological_process def: "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015718 ! monocarboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:30089 ! acetate relationship: has_primary_input CHEBI:30089 ! acetate [Term] id: GO:0006847 name: plasma membrane acetate transport namespace: biological_process def: "The directed movement of acetate across a plasma membrane." [GOC:ai] is_a: GO:0035433 ! acetate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:30089 ! acetate intersection_of: results_in_transport_across GO:0005886 ! plasma membrane relationship: results_in_transport_across GO:0005886 ! plasma membrane [Term] id: GO:0006858 name: extracellular transport namespace: biological_process def: "The transport of substances that occurs outside cells." [GOC:go_curators] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: occurs_in GO:0005576 ! extracellular region relationship: occurs_in GO:0005576 ! extracellular region [Term] id: GO:0006860 name: extracellular amino acid transport namespace: biological_process def: "The directed extracellular movement of amino acids." [GOC:ai] is_a: GO:0006858 ! extracellular transport is_a: GO:0006865 ! amino acid transport intersection_of: GO:0006865 ! amino acid transport intersection_of: occurs_in GO:0005576 ! extracellular region [Term] id: GO:0006865 name: amino acid transport namespace: biological_process alt_id: GO:0006866 def: "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir subset: goslim_yeast is_a: GO:0015849 ! organic acid transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33709 ! amino acid relationship: has_primary_input CHEBI:33709 ! amino acid [Term] id: GO:0006869 name: lipid transport namespace: biological_process def: "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [ISBN:0198506732] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid relationship: part_of GO:0010876 ! lipid localization [Term] id: GO:0006886 name: intracellular protein transport namespace: biological_process alt_id: GO:0032779 def: "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." [GOC:mah] subset: goslim_generic subset: prokaryote_subset synonym: "copper-induced intracellular protein transport" RELATED [GOC:al] is_a: GO:0015031 ! protein transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: part_of GO:0008104 ! protein localization [Term] id: GO:0006887 name: exocytosis namespace: biological_process alt_id: GO:0016194 alt_id: GO:0016195 def: "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." [GOC:mah, ISBN:0716731363, PMID:22323285] subset: goslim_yeast synonym: "nonselective vesicle exocytosis" RELATED [] synonym: "vesicle exocytosis" EXACT [] xref: Wikipedia:Exocytosis is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0032940 ! secretion by cell intersection_of: GO:0006810 ! transport intersection_of: process_has_causal_agent GO:0070382 ! exocytic vesicle relationship: has_part GO:0099500 ! vesicle fusion to plasma membrane relationship: process_has_causal_agent GO:0070382 ! exocytic vesicle [Term] id: GO:0006892 name: post-Golgi vesicle-mediated transport namespace: biological_process def: "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." [GOC:ai, GOC:mah] synonym: "post-Golgi transport" EXACT [] is_a: GO:0048193 ! Golgi vesicle transport [Term] id: GO:0006893 name: Golgi to plasma membrane transport namespace: biological_process def: "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." [ISBN:0716731363] synonym: "Golgi to plasma membrane vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0098876 ! vesicle-mediated transport to the plasma membrane intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus relationship: has_target_start_location GO:0005794 ! Golgi apparatus [Term] id: GO:0006896 name: Golgi to vacuole transport namespace: biological_process def: "The directed movement of substances from the Golgi to the vacuole." [GOC:ai] synonym: "Golgi to vacuole vesicle-mediated transport" EXACT [] is_a: GO:0006892 ! post-Golgi vesicle-mediated transport is_a: GO:0007034 ! vacuolar transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: has_target_end_location GO:0005773 ! vacuole intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: has_target_end_location GO:0005773 ! vacuole relationship: has_target_start_location GO:0005794 ! Golgi apparatus [Term] id: GO:0006903 name: vesicle targeting namespace: biological_process def: "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo." [GOC:mah, PMID:17335816] is_a: GO:0009987 ! cellular process relationship: part_of GO:0016192 ! vesicle-mediated transport relationship: part_of GO:0051650 ! establishment of vesicle localization [Term] id: GO:0006906 name: vesicle fusion namespace: biological_process def: "Fusion of the membrane of a transport vesicle with its target membrane." [GOC:jid] is_a: GO:0016050 ! vesicle organization is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0012506 ! vesicle membrane relationship: part_of GO:0016192 ! vesicle-mediated transport relationship: results_in_fusion_of GO:0012506 ! vesicle membrane [Term] id: GO:0006915 name: apoptotic process namespace: biological_process alt_id: GO:0006917 alt_id: GO:0008632 def: "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:cjm, GOC:dhl, GOC:ecd, GOC:go_curators, GOC:mtg_apoptosis, GOC:tb, ISBN:0198506732, PMID:18846107, PMID:21494263] synonym: "activation of apoptosis" NARROW [] synonym: "apoptosis" NARROW [] synonym: "apoptosis activator activity" RELATED [] synonym: "apoptosis signaling" NARROW [] synonym: "apoptotic cell death" EXACT [GOC:sl] synonym: "apoptotic program" NARROW [GOC:add] synonym: "apoptotic programmed cell death" EXACT [] synonym: "caspase-dependent programmed cell death" RELATED [] synonym: "cell suicide" BROAD [] synonym: "cellular suicide" BROAD [] synonym: "commitment to apoptosis" RELATED [] synonym: "induction of apoptosis" RELATED [] synonym: "induction of apoptosis by p53" RELATED [] synonym: "programmed cell death by apoptosis" EXACT [] synonym: "signaling (initiator) caspase activity" RELATED [] synonym: "type I programmed cell death" NARROW [] xref: Wikipedia:Apoptosis is_a: GO:0012501 ! programmed cell death relationship: ends_with GO:0097194 ! execution phase of apoptosis relationship: in_taxon NCBITaxon:33154 {all_only="true"} ! Opisthokonta relationship: only_in_taxon NCBITaxon:33154 ! Opisthokonta relationship: starts_with GO:0097190 ! apoptotic signaling pathway property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:4896 [Term] id: GO:0006921 name: cellular component disassembly involved in execution phase of apoptosis namespace: biological_process def: "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb] synonym: "cellular component disassembly involved in apoptosis" NARROW [] synonym: "cellular component disassembly involved in apoptotic process" BROAD [] synonym: "disassembly of cell structures" BROAD [] is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: part_of GO:0097194 ! execution phase of apoptosis relationship: part_of GO:0097194 ! execution phase of apoptosis [Term] id: GO:0006936 name: muscle contraction namespace: biological_process def: "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." [GOC:ef, GOC:mtg_muscle, ISBN:0198506732] subset: goslim_pir xref: Wikipedia:Muscle_contraction is_a: GO:0003012 ! muscle system process relationship: occurs_in UBERON:0002385 ! muscle tissue [Term] id: GO:0006937 name: regulation of muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle contraction." [GOC:go_curators] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006936 ! muscle contraction relationship: regulates GO:0006936 ! muscle contraction [Term] id: GO:0006939 name: smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." [GOC:ef, GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "visceral muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue relationship: occurs_in UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0006940 name: regulation of smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006939 ! smooth muscle contraction relationship: regulates GO:0006939 ! smooth muscle contraction [Term] id: GO:0006941 name: striated muscle contraction namespace: biological_process def: "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." [GOC:jl, GOC:mtg_muscle, ISBN:0198506732] synonym: "sarcomeric muscle contraction" EXACT [] is_a: GO:0006936 ! muscle contraction relationship: occurs_in UBERON:0002036 ! striated muscle tissue [Term] id: GO:0006942 name: regulation of striated muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] is_a: GO:0006937 ! regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006941 ! striated muscle contraction relationship: regulates GO:0006941 ! striated muscle contraction [Term] id: GO:0006949 name: syncytium formation namespace: biological_process def: "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." [ISBN:0198506732] subset: goslim_pir is_a: GO:0009987 ! cellular process is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of CL:0000228 ! multinucleate cell relationship: results_in_formation_of CL:0000228 ! multinucleate cell [Term] id: GO:0006950 name: response to stress namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant synonym: "response to abiotic stress" RELATED [] synonym: "response to biotic stress" RELATED [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0006952 name: defense response namespace: biological_process alt_id: GO:0002217 alt_id: GO:0042829 def: "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." [GOC:go_curators] synonym: "antimicrobial peptide activity" RELATED [] synonym: "defence response" EXACT [] synonym: "defense/immunity protein activity" RELATED [] synonym: "physiological defense response" EXACT [] is_a: GO:0006950 ! response to stress [Term] id: GO:0006954 name: inflammatory response namespace: biological_process def: "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." [GO_REF:0000022, ISBN:0198506732] subset: goslim_generic synonym: "inflammation" BROAD [] xref: Wikipedia:Inflammation is_a: GO:0006952 ! defense response relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0006955 name: immune response namespace: biological_process def: "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." [GO_REF:0000022, GOC:add] subset: goslim_drosophila is_a: GO:0002376 ! immune system process is_a: GO:0050896 ! response to stimulus [Term] id: GO:0006996 name: organelle organization namespace: biological_process alt_id: GO:1902589 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] subset: goslim_candida subset: goslim_pir synonym: "organelle organisation" EXACT [] synonym: "organelle organization and biogenesis" RELATED [GOC:dph, GOC:jl, GOC:mah] synonym: "single organism organelle organization" EXACT [GOC:TermGenie] synonym: "single-organism organelle organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0043226 ! organelle relationship: results_in_organization_of GO:0043226 ! organelle created_by: jl creation_date: 2013-12-19T15:25:51Z [Term] id: GO:0006997 name: nucleus organization namespace: biological_process alt_id: GO:0048287 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] subset: goslim_candida subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "nuclear morphology" RELATED [] synonym: "nuclear organisation" EXACT [] synonym: "nuclear organization" EXACT [] synonym: "nuclear organization and biogenesis" RELATED [GOC:mah] synonym: "nucleus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005634 ! nucleus relationship: results_in_organization_of GO:0005634 ! nucleus [Term] id: GO:0006998 name: nuclear envelope organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." [GOC:dph, GOC:ems, GOC:jl, GOC:mah] synonym: "nuclear envelope organisation" EXACT [GOC:mah] synonym: "nuclear envelope organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005635 ! nuclear envelope relationship: part_of GO:0006997 ! nucleus organization relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0005635 ! nuclear envelope [Term] id: GO:0007000 name: nucleolus organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." [GOC:dph, GOC:jid, GOC:jl, GOC:mah] synonym: "nucleolus organisation" EXACT [] synonym: "nucleolus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006997 ! nucleus organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005730 ! nucleolus relationship: results_in_organization_of GO:0005730 ! nucleolus [Term] id: GO:0007009 name: plasma membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl synonym: "plasma membrane organisation" EXACT [] synonym: "plasma membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005886 ! plasma membrane relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0005886 ! plasma membrane [Term] id: GO:0007010 name: cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_yeast subset: prokaryote_subset synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] synonym: "cytoskeletal regulator activity" RELATED [] synonym: "cytoskeleton organisation" EXACT [] synonym: "cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005856 ! cytoskeleton relationship: results_in_organization_of GO:0005856 ! cytoskeleton [Term] id: GO:0007015 name: actin filament organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:mah] synonym: "actin filament organisation" EXACT [] synonym: "regulation of actin filament localization" NARROW [] is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005884 ! actin filament relationship: part_of GO:0030036 ! actin cytoskeleton organization relationship: results_in_organization_of GO:0005884 ! actin filament [Term] id: GO:0007017 name: microtubule-based process namespace: biological_process def: "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." [GOC:mah] subset: goslim_chembl is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: process_has_causal_agent GO:0005874 ! microtubule relationship: process_has_causal_agent GO:0005874 ! microtubule property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0007018 name: microtubule-based movement namespace: biological_process def: "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] subset: goslim_drosophila subset: goslim_generic is_a: GO:0007017 ! microtubule-based process [Term] id: GO:0007019 name: microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of a microtubule." [ISBN:0815316194] synonym: "microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "microtubule depolymerization during nuclear congression" NARROW [] synonym: "microtubule disassembly" EXACT [] synonym: "microtubule shortening" EXACT [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051261 ! protein depolymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005874 ! microtubule relationship: results_in_disassembly_of GO:0005874 ! microtubule [Term] id: GO:0007020 name: microtubule nucleation namespace: biological_process def: "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." [GOC:go_curators, ISBN:0815316194, PMID:12517712] xref: Wikipedia:Microtubule_nucleation is_a: GO:0000226 ! microtubule cytoskeleton organization relationship: part_of GO:0046785 ! microtubule polymerization [Term] id: GO:0007026 name: negative regulation of microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." [GOC:mah, ISBN:0815316194] synonym: "down regulation of microtubule depolymerization" EXACT [] synonym: "down-regulation of microtubule depolymerization" EXACT [] synonym: "downregulation of microtubule depolymerization" EXACT [] synonym: "inhibition of microtubule depolymerization" NARROW [] synonym: "microtubule rescue" NARROW [GOC:dph, GOC:tb] synonym: "microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of microtubule disassembly" EXACT [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901880 ! negative regulation of protein depolymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007019 ! microtubule depolymerization relationship: negatively_regulates GO:0007019 ! microtubule depolymerization [Term] id: GO:0007027 name: negative regulation of axonemal microtubule depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." [GOC:dph, GOC:mah] synonym: "axonemal microtubule stabilization" EXACT [] synonym: "negative regulation of microtubule depolymerization in axoneme" RELATED [GOC:dph] is_a: GO:0007026 ! negative regulation of microtubule depolymerization is_a: GO:0010937 ! regulation of cytoplasmic microtubule depolymerization is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization relationship: negatively_regulates GO:0060404 ! axonemal microtubule depolymerization [Term] id: GO:0007028 name: cytoplasm organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." [GOC:curators, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "cytoplasm organisation" EXACT [] synonym: "cytoplasm organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005737 ! cytoplasm relationship: results_in_organization_of GO:0005737 ! cytoplasm [Term] id: GO:0007030 name: Golgi organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "Golgi apparatus organization" EXACT [] synonym: "Golgi organisation" EXACT [] synonym: "Golgi organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005794 ! Golgi apparatus relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0005794 ! Golgi apparatus [Term] id: GO:0007033 name: vacuole organization namespace: biological_process alt_id: GO:0044086 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GOC:mah] subset: goslim_drosophila subset: goslim_pir subset: goslim_yeast synonym: "vacuolar assembly" NARROW [GOC:mah] synonym: "vacuole biogenesis" RELATED [GOC:mah] synonym: "vacuole organisation" EXACT [] synonym: "vacuole organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005773 ! vacuole relationship: results_in_organization_of GO:0005773 ! vacuole [Term] id: GO:0007034 name: vacuolar transport namespace: biological_process def: "The directed movement of substances into, out of or within a vacuole." [GOC:ai] subset: goslim_chembl is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: results_in_transport_to_from_or_in GO:0005773 ! vacuole relationship: results_in_transport_to_from_or_in GO:0005773 ! vacuole [Term] id: GO:0007039 name: protein catabolic process in the vacuole namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." [GOC:mah, GOC:vw] synonym: "vacuolar protein breakdown" RELATED [] synonym: "vacuolar protein catabolic process" RELATED [] synonym: "vacuolar protein catabolism" RELATED [] synonym: "vacuolar protein degradation" RELATED [] is_a: GO:0030163 ! protein catabolic process intersection_of: GO:0030163 ! protein catabolic process intersection_of: occurs_in GO:0005773 ! vacuole relationship: occurs_in GO:0005773 ! vacuole [Term] id: GO:0007043 name: cell-cell junction assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." [GOC:ai] synonym: "intercellular junction assembly" EXACT [] is_a: GO:0034329 ! cell junction assembly is_a: GO:0045216 ! cell-cell junction organization intersection_of: GO:0034329 ! cell junction assembly intersection_of: results_in_assembly_of GO:0005911 ! cell-cell junction relationship: results_in_assembly_of GO:0005911 ! cell-cell junction [Term] id: GO:0007049 name: cell cycle namespace: biological_process def: "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." [GOC:go_curators, GOC:mtg_cell_cycle] subset: gocheck_do_not_manually_annotate subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_pir subset: goslim_plant synonym: "cell-division cycle" EXACT [] xref: Wikipedia:Cell_cycle is_a: GO:0009987 ! cellular process [Term] id: GO:0007059 name: chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:jl, GOC:mah, GOC:mtg_cell_cycle, GOC:vw] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_yeast subset: prokaryote_subset synonym: "chromosome division" EXACT [] synonym: "chromosome transmission" RELATED [] xref: Wikipedia:Chromosome_segregation is_a: GO:0022402 ! cell cycle process [Term] id: GO:0007076 name: mitotic chromosome condensation namespace: biological_process def: "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." [GOC:mah, ISBN:0815316194] is_a: GO:0030261 ! chromosome condensation is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0030261 ! chromosome condensation intersection_of: part_of GO:0000278 ! mitotic cell cycle relationship: part_of GO:0000070 ! mitotic sister chromatid segregation [Term] id: GO:0007077 name: mitotic nuclear membrane disassembly namespace: biological_process def: "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." [GOC:bf, PMID:32848252] synonym: "local NEB" BROAD [] synonym: "mitotic nuclear envelope breakdown" EXACT [] synonym: "mitotic nuclear envelope catabolism" RELATED [] synonym: "mitotic nuclear envelope degradation" RELATED [] synonym: "mitotic nuclear envelope disassembly" RELATED [] synonym: "NEB" BROAD [] synonym: "nuclear envelope breakdown" BROAD [] is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0000278 ! mitotic cell cycle [Term] id: GO:0007088 name: regulation of mitotic nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "regulation of mitosis" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0140014 ! mitotic nuclear division relationship: regulates GO:0140014 ! mitotic nuclear division [Term] id: GO:0007097 name: nuclear migration namespace: biological_process alt_id: GO:0040023 def: "The directed movement of the nucleus to a specific location within a cell." [GOC:ai] synonym: "establishment of cell nucleus localization" RELATED [] synonym: "establishment of localization of nucleus" RELATED [] synonym: "establishment of nucleus localisation" RELATED [GOC:mah] synonym: "establishment of nucleus localization" RELATED [] synonym: "establishment of position of nucleus" EXACT [] synonym: "nuclear movement" EXACT [] synonym: "nuclear positioning" EXACT [] synonym: "nucleus migration" EXACT [] synonym: "nucleus positioning" EXACT [] synonym: "positioning of nucleus" EXACT [] is_a: GO:0046907 ! intracellular transport is_a: GO:0051647 ! nucleus localization is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0005634 ! nucleus [Term] id: GO:0007113 name: endomitotic cell cycle namespace: biological_process def: "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." [GOC:curators, GOC:dos, GOC:expert_vm] comment: Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins. synonym: "endomitosis" RELATED [] xref: Wikipedia:Mitosis#Endomitosis is_a: GO:0000278 ! mitotic cell cycle [Term] id: GO:0007135 name: meiosis II namespace: biological_process def: "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." [GOC:dph, GOC:mah, ISBN:0198547684] synonym: "meiosis II nuclear division" EXACT [] xref: Wikipedia:Meiosis#Meiosis_II is_a: GO:0061983 ! meiosis II cell cycle process is_a: GO:0140013 ! meiotic nuclear division [Term] id: GO:0007140 name: male meiotic nuclear division namespace: biological_process def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." [GOC:dph, GOC:mah, GOC:vw] synonym: "male meiosis" RELATED [] synonym: "male nuclear division" BROAD [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0048232 ! male gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle relationship: part_of GO:0048232 ! male gamete generation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007142 name: male meiosis II namespace: biological_process def: "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline." [GOC:dph, GOC:mah] synonym: "male meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007140 ! male meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: part_of GO:0048232 ! male gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0007143 name: female meiotic nuclear division namespace: biological_process def: "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." [GOC:dph, GOC:ems, GOC:mah, GOC:vw] comment: Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'. synonym: "female meiosis" BROAD [] synonym: "female meiotic division" BROAD [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0140013 ! meiotic nuclear division intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0007292 ! female gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle relationship: part_of GO:0007292 ! female gamete generation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0007147 name: female meiosis II namespace: biological_process def: "The cell cycle process in which the second meiotic division occurs in the female germline." [GOC:mah] synonym: "female meiosis II nuclear division" EXACT [] is_a: GO:0007135 ! meiosis II is_a: GO:0007143 ! female meiotic nuclear division intersection_of: GO:0007135 ! meiosis II intersection_of: part_of GO:0007292 ! female gamete generation intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0007154 name: cell communication namespace: biological_process def: "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:mah] subset: goslim_pir subset: goslim_plant xref: Wikipedia:Cell_signaling is_a: GO:0009987 ! cellular process [Term] id: GO:0007155 name: cell adhesion namespace: biological_process alt_id: GO:0098602 def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe subset: prokaryote_subset synonym: "cell adhesion molecule activity" RELATED [] synonym: "single organism cell adhesion" RELATED [] xref: Wikipedia:Cell_adhesion is_a: GO:0009987 ! cellular process created_by: dos creation_date: 2014-04-15T15:59:10Z [Term] id: GO:0007159 name: leukocyte cell-cell adhesion namespace: biological_process def: "The attachment of a leukocyte to another cell via adhesion molecules." [GOC:go_curators] synonym: "leukocyte adhesion" EXACT [] synonym: "leukocyte cell adhesion" EXACT [] is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: has_participant CL:0000738 ! leukocyte relationship: has_participant CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon_Union:0000023 [Term] id: GO:0007162 name: negative regulation of cell adhesion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "cell adhesion receptor inhibitor activity" RELATED [] synonym: "down regulation of cell adhesion" EXACT [] synonym: "down-regulation of cell adhesion" EXACT [] synonym: "downregulation of cell adhesion" EXACT [] synonym: "inhibition of cell adhesion" NARROW [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007155 ! cell adhesion relationship: negatively_regulates GO:0007155 ! cell adhesion [Term] id: GO:0007163 name: establishment or maintenance of cell polarity namespace: biological_process alt_id: GO:0030012 alt_id: GO:0030467 def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: prokaryote_subset synonym: "cell polarity" RELATED [GOC:mah, GOC:vw] synonym: "establishment and/or maintenance of cell polarity" RELATED [] synonym: "establishment and/or maintenance of cell polarization" RELATED [] is_a: GO:0009987 ! cellular process [Term] id: GO:0007165 name: signal transduction namespace: biological_process alt_id: GO:0023014 alt_id: GO:0023015 alt_id: GO:0023016 alt_id: GO:0023033 alt_id: GO:0023045 def: "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." [GOC:go_curators, GOC:mtg_signaling_feb11] comment: Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "signal transduction by cis-phosphorylation" NARROW [] synonym: "signal transduction by conformational transition" NARROW [] synonym: "signal transduction by protein phosphorylation" NARROW [] synonym: "signal transduction by trans-phosphorylation" NARROW [] synonym: "signaling cascade" NARROW [] synonym: "signaling pathway" RELATED [] synonym: "signalling cascade" NARROW [] synonym: "signalling pathway" RELATED [GOC:mah] xref: Wikipedia:Signal_transduction is_a: GO:0009987 ! cellular process is_a: GO:0050794 ! regulation of cellular process relationship: part_of GO:0007154 ! cell communication relationship: part_of GO:0023052 ! signaling relationship: part_of GO:0051716 ! cellular response to stimulus [Term] id: GO:0007267 name: cell-cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." [GOC:dos, GOC:mah] subset: goslim_chembl subset: goslim_plant synonym: "cell-cell signalling" EXACT [] is_a: GO:0007154 ! cell communication is_a: GO:0023052 ! signaling [Term] id: GO:0007268 name: chemical synaptic transmission namespace: biological_process def: "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:jl, MeSH:D009435] subset: goslim_synapse synonym: "neurotransmission" RELATED [GOC:dph] synonym: "signal transmission across a synapse" BROAD [] synonym: "synaptic transmission" BROAD [] xref: Wikipedia:Neurotransmission is_a: GO:0098916 ! anterograde trans-synaptic signaling relationship: has_participant GO:0045202 ! synapse [Term] id: GO:0007269 name: neurotransmitter secretion namespace: biological_process alt_id: GO:0010554 def: "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." [GOC:dph] comment: A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. subset: goslim_synapse synonym: "neurotransmitter release" EXACT [] synonym: "neurotransmitter secretory pathway" EXACT [] is_a: GO:0001505 ! regulation of neurotransmitter levels is_a: GO:0006836 ! neurotransmitter transport is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0099643 ! signal release from synapse relationship: occurs_in GO:0098793 ! presynapse [Term] id: GO:0007271 name: synaptic transmission, cholinergic namespace: biological_process def: "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." [GOC:dos, Wikipedia:Cholinergic] synonym: "cholinergic synaptic transmission" EXACT [] is_a: GO:0007268 ! chemical synaptic transmission relationship: has_participant CHEBI:15355 ! acetylcholine [Term] id: GO:0007272 name: ensheathment of neurons namespace: biological_process def: "The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment." [GOC:dgh, GOC:dph, GOC:tb] synonym: "ionic insulation of neurons by glial cells" RELATED [] is_a: GO:0009987 ! cellular process relationship: has_participant CL:0000125 ! glial cell relationship: has_participant CL:0000540 ! neuron relationship: part_of GO:0007399 ! nervous system development [Term] id: GO:0007274 name: neuromuscular synaptic transmission namespace: biological_process def: "The process of synaptic transmission from a neuron to a muscle, across a synapse." [GOC:dos, GOC:jl, MeSH:D009435] is_a: GO:0007268 ! chemical synaptic transmission [Term] id: GO:0007275 name: multicellular organism development namespace: biological_process def: "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:dph, GOC:ems, GOC:isa_complete, GOC:tb] comment: Note that this term was 'developmental process'. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism relationship: results_in_developmental_progression_of UBERON:0000468 ! multicellular organism property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21234" xsd:anyURI [Term] id: GO:0007276 name: gamete generation namespace: biological_process alt_id: GO:0009552 def: "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." [GOC:ems, GOC:mtg_sensu] synonym: "gametogenesis" RELATED [] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0019953 ! sexual reproduction property_value: RO:0002161 NCBITaxon_Union:0000023 [Term] id: GO:0007281 name: germ cell development namespace: biological_process def: "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." [GOC:go_curators] synonym: "germ-cell development" EXACT [] synonym: "primordial germ cell development" NARROW [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000586 ! germ cell relationship: part_of GO:0007276 ! gamete generation relationship: results_in_development_of CL:0000586 ! germ cell [Term] id: GO:0007283 name: spermatogenesis namespace: biological_process def: "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." [GOC:jid, ISBN:9780878933846, PMID:28073824, PMID:30990821] synonym: "generation of spermatozoa" EXACT systematic_synonym [] xref: Wikipedia:Spermatogenesis is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048232 ! male gamete generation [Term] id: GO:0007284 name: spermatogonial cell division namespace: biological_process def: "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)." [GOC:bf, GOC:pr, ISBN:0879694238] comment: See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'. synonym: "spermatogonium division" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000020 ! spermatogonium relationship: has_input CL:0000020 ! spermatogonium relationship: part_of GO:0007283 ! spermatogenesis [Term] id: GO:0007285 name: primary spermatocyte growth namespace: biological_process def: "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." [GOC:jid, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000656 ! primary spermatocyte relationship: part_of GO:0007283 ! spermatogenesis relationship: results_in_growth_of CL:0000656 ! primary spermatocyte [Term] id: GO:0007286 name: spermatid development namespace: biological_process def: "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." [GOC:dph, GOC:go_curators] synonym: "spermatid cell development" EXACT [] synonym: "spermiogenesis" EXACT [] xref: Wikipedia:Spermiogenesis is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000018 ! spermatid relationship: part_of GO:0048515 ! spermatid differentiation relationship: results_in_development_of CL:0000018 ! spermatid [Term] id: GO:0007288 name: sperm axoneme assembly namespace: biological_process def: "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement." [GOC:bf, GOC:cilia, ISBN:0198547684] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0035082 ! axoneme assembly intersection_of: GO:0035082 ! axoneme assembly intersection_of: occurs_in CL:0000019 ! sperm relationship: occurs_in CL:0000019 ! sperm relationship: part_of GO:0120316 ! sperm flagellum assembly [Term] id: GO:0007289 name: spermatid nucleus differentiation namespace: biological_process def: "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." [GOC:bf, GOC:dph, GOC:jl, GOC:mah] comment: See also the Cell Ontology term 'spermatid ; CL:0000018'. synonym: "spermatid nuclear differentiation" EXACT [] is_a: GO:0006997 ! nucleus organization is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism relationship: part_of GO:0007286 ! spermatid development [Term] id: GO:0007292 name: female gamete generation namespace: biological_process def: "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." [GOC:dph, ISBN:0198506732] is_a: GO:0007276 ! gamete generation [Term] id: GO:0007293 name: germarium-derived egg chamber formation namespace: biological_process def: "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048477 ! oogenesis [Term] id: GO:0007308 name: oocyte construction namespace: biological_process alt_id: GO:0048110 def: "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:ems, GOC:mtg_sensu, GOC:tb, ISBN:0198506732] synonym: "oocyte arrangement" EXACT [GOC:dph, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation intersection_of: GO:0032502 ! developmental process intersection_of: results_in_formation_of CL:0000023 ! oocyte relationship: part_of GO:0048599 ! oocyte development relationship: results_in_formation_of CL:0000023 ! oocyte [Term] id: GO:0007309 name: oocyte axis specification namespace: biological_process alt_id: GO:0048111 def: "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, ISBN:0879694238] synonym: "oocyte axis determination" RELATED [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009798 ! axis specification intersection_of: GO:0009798 ! axis specification intersection_of: occurs_in CL:0000023 ! oocyte relationship: occurs_in CL:0000023 ! oocyte relationship: part_of GO:0007308 ! oocyte construction [Term] id: GO:0007314 name: oocyte anterior/posterior axis specification namespace: biological_process alt_id: GO:0048112 def: "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster." [GOC:dph, GOC:mtg_sensu, GOC:tb, ISBN:0879694238] synonym: "oocyte anterior/posterior axis determination" EXACT [GOC:dph, GOC:tb] is_a: GO:0007309 ! oocyte axis specification is_a: GO:0009948 ! anterior/posterior axis specification intersection_of: GO:0009948 ! anterior/posterior axis specification intersection_of: occurs_in CL:0000023 ! oocyte relationship: part_of GO:0008358 ! maternal determination of anterior/posterior axis, embryo [Term] id: GO:0007320 name: insemination namespace: biological_process def: "The introduction of semen or sperm into the genital tract of a female." [ISBN:0582227089] xref: Wikipedia:Insemination is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0007620 ! copulation [Term] id: GO:0007338 name: single fertilization namespace: biological_process def: "The union of male and female gametes to form a zygote." [GOC:ems, GOC:mtg_sensu] synonym: "zygote biosynthesis" RELATED [] synonym: "zygote formation" RELATED [] is_a: GO:0009566 ! fertilization relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:58024 [Term] id: GO:0007343 name: egg activation namespace: biological_process def: "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." [GOC:bf, PMID:9630751] xref: Wikipedia:Egg_activation is_a: GO:0001775 ! cell activation is_a: GO:0022414 ! reproductive process intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000025 ! egg cell relationship: has_input CL:0000025 ! egg cell relationship: part_of GO:0007338 ! single fertilization [Term] id: GO:0007346 name: regulation of mitotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "mitotic cell cycle modulation" EXACT [] synonym: "mitotic cell cycle regulation" EXACT [] synonym: "mitotic cell cycle regulator" RELATED [] synonym: "modulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000278 ! mitotic cell cycle relationship: regulates GO:0000278 ! mitotic cell cycle [Term] id: GO:0007350 name: blastoderm segmentation namespace: biological_process def: "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0009880 ! embryonic pattern specification is_a: GO:0035282 ! segmentation [Term] id: GO:0007351 name: tripartite regional subdivision namespace: biological_process def: "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions." [GOC:dph, GOC:isa_complete, http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0003002 ! regionalization relationship: part_of GO:0007350 ! blastoderm segmentation [Term] id: GO:0007354 name: zygotic determination of anterior/posterior axis, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: GO:0008595 ! anterior/posterior axis specification, embryo intersection_of: occurs_in CL:0000365 ! animal zygote relationship: occurs_in CL:0000365 ! animal zygote [Term] id: GO:0007369 name: gastrulation namespace: biological_process def: "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GOC:curators, ISBN:9780878933846] subset: goslim_drosophila xref: Wikipedia:Gastrulation is_a: GO:0048598 ! embryonic morphogenesis relationship: has_part GO:0001705 ! ectoderm formation relationship: has_part GO:0001706 ! endoderm formation relationship: has_part GO:0001707 ! mesoderm formation [Term] id: GO:0007389 name: pattern specification process namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." [GOC:go_curators, GOC:isa_complete, ISBN:0521436125] subset: goslim_drosophila synonym: "pattern biosynthesis" RELATED [] synonym: "pattern formation" RELATED [] is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0007398 name: ectoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000924 ! ectoderm relationship: results_in_development_of UBERON:0000924 ! ectoderm [Term] id: GO:0007399 name: nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." [GOC:dgh] subset: goslim_drosophila synonym: "pan-neural process" RELATED [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001016 ! nervous system relationship: results_in_development_of UBERON:0001016 ! nervous system [Term] id: GO:0007405 name: neuroblast proliferation namespace: biological_process alt_id: GO:0043349 alt_id: GO:0043350 def: "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." [GOC:ai, GOC:mtg_sensu, GOC:sart] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: acts_on_population_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048699 ! generation of neurons [Term] id: GO:0007406 name: negative regulation of neuroblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." [GOC:ai] synonym: "down regulation of neuroblast proliferation" EXACT [] synonym: "down-regulation of neuroblast proliferation" EXACT [] synonym: "downregulation of neuroblast proliferation" EXACT [] synonym: "inhibition of neuroblast proliferation" NARROW [] synonym: "suppression of neuroblast proliferation" EXACT [] is_a: GO:0050768 ! negative regulation of neurogenesis is_a: GO:1902692 ! regulation of neuroblast proliferation is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007405 ! neuroblast proliferation relationship: negatively_regulates GO:0007405 ! neuroblast proliferation [Term] id: GO:0007407 name: neuroblast activation namespace: biological_process alt_id: GO:0043351 alt_id: GO:0043352 def: "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048699 ! generation of neurons [Term] id: GO:0007409 name: axonogenesis namespace: biological_process alt_id: GO:0007410 def: "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells." [GOC:dph, GOC:jid, GOC:pg, GOC:pr, ISBN:0198506732] comment: Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon). synonym: "axon growth" NARROW [] synonym: "axon morphogenesis" EXACT [GOC:bf, PMID:23517308] synonym: "neuron long process generation" EXACT systematic_synonym [] is_a: GO:0048812 ! neuron projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0030424 ! axon relationship: part_of GO:0048667 ! cell morphogenesis involved in neuron differentiation relationship: part_of GO:0061564 ! axon development relationship: results_in_morphogenesis_of GO:0030424 ! axon [Term] id: GO:0007416 name: synapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." [GOC:mah] subset: goslim_synapse synonym: "synapse biogenesis" EXACT [GOC:mah] synonym: "synaptogenesis" EXACT [GOC:mah] xref: Wikipedia:Synaptogenesis is_a: GO:0034329 ! cell junction assembly is_a: GO:0050808 ! synapse organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0045202 ! synapse relationship: part_of GO:0007399 ! nervous system development relationship: results_in_assembly_of GO:0045202 ! synapse [Term] id: GO:0007417 name: central nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GOC:bf, GOC:jid, ISBN:0582227089] synonym: "CNS development" EXACT [] xref: Wikipedia:Neural_development is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001017 ! central nervous system relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0001017 ! central nervous system [Term] id: GO:0007420 name: brain development namespace: biological_process def: "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dph, GOC:jid, GOC:tb, UBERON:0000955] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000955 ! brain relationship: part_of GO:0007417 ! central nervous system development relationship: part_of GO:0060322 ! head development relationship: results_in_development_of UBERON:0000955 ! brain [Term] id: GO:0007422 name: peripheral nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GOC:go_curators, UBERON:0000010] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000010 ! peripheral nervous system relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0000010 ! peripheral nervous system [Term] id: GO:0007423 name: sensory organ development namespace: biological_process def: "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." [GOC:go_curators] subset: goslim_drosophila synonym: "sense organ development" EXACT [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000020 ! sense organ relationship: results_in_development_of UBERON:0000020 ! sense organ [Term] id: GO:0007439 name: ectodermal digestive tract development namespace: biological_process def: "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." [GOC:curators] synonym: "ectodermal gut development" RELATED [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_formation_of UBERON:0004906 ! ectodermal part of digestive tract relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_formation_of UBERON:0004906 ! ectodermal part of digestive tract [Term] id: GO:0007440 name: foregut morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the foregut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001041 ! foregut relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: results_in_morphogenesis_of UBERON:0001041 ! foregut [Term] id: GO:0007442 name: hindgut morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the hindgut are generated and organized." [GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001046 ! hindgut relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: part_of GO:0061525 ! hindgut development relationship: results_in_morphogenesis_of UBERON:0001046 ! hindgut [Term] id: GO:0007492 name: endoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." [GOC:dph, GOC:tb] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000925 ! endoderm relationship: results_in_development_of UBERON:0000925 ! endoderm [Term] id: GO:0007494 name: midgut development namespace: biological_process def: "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." [GOC:jid, UBERON:0001045] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001045 ! midgut relationship: results_in_development_of UBERON:0001045 ! midgut [Term] id: GO:0007498 name: mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." [GOC:dph, GOC:tb] subset: goslim_drosophila is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000926 ! mesoderm relationship: results_in_development_of UBERON:0000926 ! mesoderm [Term] id: GO:0007506 name: gonadal mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003855 ! gonad mesenchyme relationship: part_of GO:0008406 ! gonad development relationship: results_in_development_of UBERON:0003855 ! gonad mesenchyme [Term] id: GO:0007507 name: heart development namespace: biological_process alt_id: GO:0007511 def: "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." [GOC:jid, UBERON:0000948] synonym: "cardiac development" RELATED [] synonym: "dorsal vessel development" NARROW [] xref: Wikipedia:Heart_development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007100 ! primary circulatory organ relationship: part_of GO:0072359 ! circulatory system development relationship: results_in_development_of UBERON:0007100 ! primary circulatory organ [Term] id: GO:0007517 name: muscle organ development namespace: biological_process def: "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." [GOC:jid, ISBN:0198506732] is_a: GO:0048513 ! animal organ development is_a: GO:0061061 ! muscle structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001630 ! muscle organ relationship: results_in_development_of UBERON:0001630 ! muscle organ [Term] id: GO:0007519 name: skeletal muscle tissue development namespace: biological_process alt_id: GO:0048637 def: "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." [GOC:mtg_muscle] synonym: "myogenesis" RELATED [] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001134 ! skeletal muscle tissue relationship: part_of GO:0060538 ! skeletal muscle organ development relationship: results_in_development_of UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0007528 name: neuromuscular junction development namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." [GOC:mtg_OBO2OWL_2013] synonym: "neuromuscular junction organization" EXACT [] synonym: "neuromuscular junction stability" RELATED [GOC:pr] synonym: "NMJ stability" RELATED [GOC:pr] is_a: GO:0050808 ! synapse organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031594 ! neuromuscular junction relationship: results_in_organization_of GO:0031594 ! neuromuscular junction [Term] id: GO:0007548 name: sex differentiation namespace: biological_process def: "The establishment of the sex of an organism by physical differentiation." [GOC:ai] xref: Wikipedia:Sexual_differentiation is_a: GO:0003006 ! developmental process involved in reproduction [Term] id: GO:0007565 name: female pregnancy namespace: biological_process def: "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." [ISBN:0192800825] subset: goslim_chembl synonym: "carrying of young" RELATED [] synonym: "gestation" EXACT [] xref: Wikipedia:Gestation is_a: GO:0044703 ! multi-organism reproductive process is_a: GO:0044706 ! multi-multicellular organism process relationship: in_taxon NCBITaxon:40674 {all_only="true"} ! Mammalia relationship: only_in_taxon NCBITaxon:40674 ! Mammalia [Term] id: GO:0007566 name: embryo implantation namespace: biological_process def: "Attachment of the blastocyst to the uterine lining." [GOC:isa_complete, http://www.medterms.com] synonym: "blastocyst implantation" EXACT [] is_a: GO:0022414 ! reproductive process relationship: part_of GO:0007275 ! multicellular organism development relationship: part_of GO:0007565 ! female pregnancy [Term] id: GO:0007585 name: respiratory gaseous exchange by respiratory system namespace: biological_process def: "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [ISBN:0198506732] subset: goslim_chembl synonym: "breathing" BROAD [] synonym: "respiration" BROAD [] is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0007586 name: digestion namespace: biological_process def: "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, ISBN:0198506732] subset: goslim_chembl subset: goslim_pir xref: Wikipedia:Digestion is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0007588 name: excretion namespace: biological_process def: "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." [ISBN:0192801023] subset: gocheck_do_not_annotate subset: goslim_pir xref: Wikipedia:Excretion is_a: GO:0003008 ! system process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI [Term] id: GO:0007589 name: body fluid secretion namespace: biological_process def: "The controlled release of a fluid by a cell or tissue in an animal." [GOC:ai, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0046903 ! secretion is_a: GO:0050878 ! regulation of body fluid levels [Term] id: GO:0007600 name: sensory perception namespace: biological_process def: "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai, GOC:dph] subset: goslim_drosophila xref: Wikipedia:Perception is_a: GO:0050877 ! nervous system process [Term] id: GO:0007601 name: visual perception namespace: biological_process def: "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." [GOC:ai] synonym: "sense of sight" EXACT [] synonym: "sensory visual perception" EXACT [] synonym: "vision" EXACT [] xref: Wikipedia:Visual_perception is_a: GO:0050953 ! sensory perception of light stimulus [Term] id: GO:0007605 name: sensory perception of sound namespace: biological_process def: "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." [GOC:ai] synonym: "hearing" EXACT [] synonym: "perception of sound" EXACT [] xref: Wikipedia:Hearing_(sense) is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0007606 name: sensory perception of chemical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "chemosensory perception" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0007608 name: sensory perception of smell namespace: biological_process def: "The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process." [GOC:ai] synonym: "olfaction" EXACT [] synonym: "scent perception" EXACT [] synonym: "sense of smell" EXACT [] synonym: "smell perception" EXACT [] xref: Wikipedia:Olfaction is_a: GO:0007606 ! sensory perception of chemical stimulus [Term] id: GO:0007610 name: behavior namespace: biological_process alt_id: GO:0023032 alt_id: GO:0044708 alt_id: GO:0044709 def: "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." [GOC:ems, GOC:jl, ISBN:0395448956, PMID:20160973] comment: 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews.\n2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis). subset: gocheck_do_not_manually_annotate subset: goslim_agr subset: goslim_flybase_ribbon synonym: "behavioral response to stimulus" EXACT [] synonym: "behaviour" EXACT [] synonym: "behavioural response to stimulus" EXACT [] synonym: "single-organism behavior" RELATED [] xref: Wikipedia:Behavior is_a: GO:0032501 ! multicellular organismal process disjoint_from: GO:0032502 ! developmental process relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: process_has_causal_agent UBERON:0001016 ! nervous system created_by: jl creation_date: 2012-09-20T14:06:08Z [Term] id: GO:0007611 name: learning or memory namespace: biological_process def: "The acquisition and processing of information and/or the storage and retrieval of this information over time." [GOC:jid, PMID:8938125] is_a: GO:0007610 ! behavior is_a: GO:0050890 ! cognition [Term] id: GO:0007613 name: memory namespace: biological_process def: "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." [GOC:curators, ISBN:0582227089] xref: Wikipedia:Memory is_a: GO:0007611 ! learning or memory [Term] id: GO:0007617 name: mating behavior namespace: biological_process def: "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." [GOC:ai, GOC:dph] synonym: "mating behaviour" EXACT [] xref: Wikipedia:Mating_behaviour is_a: GO:0019098 ! reproductive behavior [Term] id: GO:0007620 name: copulation namespace: biological_process def: "The act of sexual union between male and female, involving the transfer of sperm." [ISBN:0721662544] is_a: GO:0007617 ! mating behavior [Term] id: GO:0007626 name: locomotory behavior namespace: biological_process def: "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." [GOC:dph] subset: goslim_drosophila synonym: "behavior via locomotion" EXACT [] synonym: "locomotion in response to stimulus" EXACT [] synonym: "locomotory behavioral response to stimulus" EXACT [] synonym: "locomotory behaviour" EXACT [] synonym: "locomotory behavioural response to stimulus" EXACT [] is_a: GO:0007610 ! behavior [Term] id: GO:0008015 name: blood circulation namespace: biological_process alt_id: GO:0070261 def: "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:mtg_heart, ISBN:0192800825] subset: goslim_pir synonym: "hemolymph circulation" RELATED [] is_a: GO:0003013 ! circulatory system process [Term] id: GO:0008016 name: regulation of heart contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "regulation of cardiac contraction" EXACT [] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060047 ! heart contraction relationship: regulates GO:0060047 ! heart contraction [Term] id: GO:0008028 name: monocarboxylic acid transmembrane transporter activity namespace: molecular_function alt_id: GO:0008505 def: "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." [GOC:ai] synonym: "monocarboxylate carrier" NARROW [] synonym: "prostaglandin/thromboxane transporter activity" NARROW [] xref: Reactome:R-HSA-429749 "SLC5A8 transports monocarboxylates from extracellular region to cytosol" xref: Reactome:R-HSA-433698 "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5624211 "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol" xref: Reactome:R-HSA-9645220 "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25384 ! monocarboxylic acid relationship: has_primary_input CHEBI:25384 ! monocarboxylic acid relationship: part_of GO:0015718 ! monocarboxylic acid transport [Term] id: GO:0008078 name: mesodermal cell migration namespace: biological_process def: "The orderly movement of mesodermal cells from one site to another." [GOC:ascb_2009, GOC:dph, GOC:mah, GOC:sat, GOC:tb, PMID:25119047] synonym: "mesoderm cell migration" EXACT [] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000222 ! mesodermal cell relationship: results_in_movement_of CL:0000222 ! mesodermal cell [Term] id: GO:0008088 name: axo-dendritic transport namespace: biological_process def: "The directed movement of organelles or molecules along microtubules in neuron projections." [ISBN:0815316194] subset: goslim_synapse synonym: "axon cargo transport" NARROW [] synonym: "axonal transport" NARROW [] synonym: "axoplasmic transport" NARROW [] xref: Wikipedia:Axoplasmic_transport is_a: GO:0010970 ! transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: occurs_in GO:0043005 ! neuron projection intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: occurs_in GO:0043005 ! neuron projection [Term] id: GO:0008089 name: anterograde axonal transport namespace: biological_process def: "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." [ISBN:0815316194] subset: goslim_synapse synonym: "anterograde axon cargo transport" EXACT [] is_a: GO:0098930 ! axonal transport intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0098793 ! presynapse intersection_of: occurs_in GO:1904115 ! axon cytoplasm intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: has_target_end_location GO:0098793 ! presynapse relationship: occurs_in GO:1904115 ! axon cytoplasm [Term] id: GO:0008090 name: retrograde axonal transport namespace: biological_process def: "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons." [ISBN:0815316194] subset: goslim_synapse synonym: "retrograde axon cargo transport" EXACT [] is_a: GO:0098930 ! axonal transport intersection_of: GO:0006810 ! transport intersection_of: has_target_start_location GO:0098793 ! presynapse intersection_of: occurs_in GO:1904115 ! axon cytoplasm intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: has_target_start_location GO:0098793 ! presynapse relationship: occurs_in GO:1904115 ! axon cytoplasm [Term] id: GO:0008104 name: protein localization namespace: biological_process alt_id: GO:0008105 alt_id: GO:0016249 alt_id: GO:0034613 def: "Any process in which a protein is transported to, or maintained in, a specific location." [GOC:ai] subset: goslim_drosophila synonym: "asymmetric protein localisation" RELATED [GOC:mah] synonym: "asymmetric protein localization" RELATED [] synonym: "cellular protein localisation" EXACT [GOC:mah] synonym: "cellular protein localization" EXACT [] synonym: "channel localizer activity" NARROW [GOC:mah] synonym: "establishment and maintenance of asymmetric protein localization" RELATED [] synonym: "establishment and maintenance of protein localization" RELATED [] synonym: "protein localisation" EXACT [GOC:mah] is_a: GO:0070727 ! cellular macromolecule localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0008150 name: biological_process namespace: biological_process alt_id: GO:0000004 alt_id: GO:0007582 alt_id: GO:0044699 def: "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] def: "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." [GOC:pdt] comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. subset: goslim_candida subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast synonym: "biological process" EXACT [] synonym: "physiological process" EXACT [] synonym: "single organism process" RELATED [] synonym: "single-organism process" RELATED [] xref: Wikipedia:Biological_process is_a: BFO:0000015 ! process is_a: http://rs.tdwg.org/dwc/terms/Event ! Event property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24968" xsd:anyURI created_by: jl creation_date: 2012-09-19T15:05:24Z [Term] id: GO:0008152 name: metabolic process namespace: biological_process alt_id: GO:0044236 alt_id: GO:0044710 def: "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." [GOC:go_curators, ISBN:0198547684] comment: Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. subset: gocheck_do_not_manually_annotate subset: goslim_chembl subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant synonym: "metabolic process resulting in cell growth" NARROW [] synonym: "metabolism" EXACT [] synonym: "metabolism resulting in cell growth" NARROW [] synonym: "multicellular organism metabolic process" NARROW [] synonym: "single-organism metabolic process" RELATED [] xref: Wikipedia:Metabolism is_a: GO:0008150 ! biological_process disjoint_from: GO:0051179 ! localization created_by: jl creation_date: 2012-10-17T15:46:40Z [Term] id: GO:0008202 name: steroid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [ISBN:0198547684] synonym: "steroid metabolism" EXACT [] xref: Wikipedia:Steroid_metabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35341 ! steroid relationship: has_primary_input_or_output CHEBI:35341 ! steroid [Term] id: GO:0008206 name: bile acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:go_curators] synonym: "bile acid metabolism" EXACT [] is_a: GO:0008202 ! steroid metabolic process is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:36235 ! bile acid anion relationship: has_primary_input_or_output CHEBI:36235 ! bile acid anion [Term] id: GO:0008219 name: cell death namespace: biological_process def: "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." [GOC:mah, GOC:mtg_apoptosis, PMID:25236395] comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term. synonym: "accidental cell death" RELATED [] synonym: "necrosis" RELATED [] is_a: GO:0009987 ! cellular process [Term] id: GO:0008272 name: sulfate transport namespace: biological_process alt_id: GO:0006870 def: "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] synonym: "sulphate transport" EXACT [] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0072348 ! sulfur compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16189 ! sulfate relationship: has_primary_input CHEBI:16189 ! sulfate [Term] id: GO:0008283 name: cell population proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population." [GOC:mah, GOC:mb] comment: This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms. subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "cell proliferation" RELATED [] is_a: GO:0009987 ! cellular process property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008284 name: positive regulation of cell population proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of cell proliferation." [GOC:go_curators] synonym: "activation of cell proliferation" NARROW [] synonym: "positive regulation of cell proliferation" RELATED [] synonym: "stimulation of cell proliferation" NARROW [] synonym: "up regulation of cell proliferation" EXACT [] synonym: "up-regulation of cell proliferation" EXACT [] synonym: "upregulation of cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008283 ! cell population proliferation relationship: positively_regulates GO:0008283 ! cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008285 name: negative regulation of cell population proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell proliferation." [GOC:go_curators] synonym: "down regulation of cell proliferation" EXACT [] synonym: "down-regulation of cell proliferation" EXACT [] synonym: "downregulation of cell proliferation" EXACT [] synonym: "inhibition of cell proliferation" NARROW [] synonym: "negative regulation of cell proliferation" RELATED [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008283 ! cell population proliferation relationship: negatively_regulates GO:0008283 ! cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0008291 name: acetylcholine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:jl, GOC:nln, ISBN:0192800752] synonym: "acetylcholine metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0042133 ! neurotransmitter metabolic process is_a: GO:1900619 ! acetate ester metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:15355 ! acetylcholine relationship: has_primary_input_or_output CHEBI:15355 ! acetylcholine [Term] id: GO:0008292 name: acetylcholine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." [GOC:jl, ISBN:0192800752] synonym: "acetylcholine anabolism" EXACT [] synonym: "acetylcholine biosynthesis" EXACT [] synonym: "acetylcholine formation" EXACT [] synonym: "acetylcholine synthesis" EXACT [] is_a: GO:0008291 ! acetylcholine metabolic process is_a: GO:0042136 ! neurotransmitter biosynthetic process is_a: GO:1900620 ! acetate ester biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:15355 ! acetylcholine relationship: has_primary_output CHEBI:15355 ! acetylcholine [Term] id: GO:0008320 name: protein transmembrane transporter activity namespace: molecular_function alt_id: GO:0015266 alt_id: GO:0015463 def: "Enables the transfer of a protein from one side of a membrane to the other." [GOC:jl] synonym: "protein channel activity" RELATED [] xref: Reactome:R-HSA-1268022 "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space" xref: Reactome:R-HSA-1299475 "TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix" xref: Reactome:R-HSA-184269 "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex" xref: Reactome:R-HSA-3149434 "Transport of GAG to the Plasma Membrane" xref: Reactome:R-HSA-5205661 "Pink1 is recruited from the cytoplasm to the mitochondria" xref: Reactome:R-HSA-5210943 "pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5210947 "pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)" xref: Reactome:R-HSA-5228406 "tetX HC transports tetX LC from target cell endosome membrane into cytosol" xref: Reactome:R-HSA-5229111 "AP4 transports APP from trans-Golgi network to endosome lumen" xref: Reactome:R-HSA-5244404 "botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244428 "botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5244506 "botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5246514 "botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol" xref: Reactome:R-HSA-5250616 "botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250884 "botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5250972 "botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol" xref: Reactome:R-HSA-5336420 "DT fragment B transports DT fragment A from target cell endosome membrane" xref: Reactome:R-HSA-9636375 "SecA2 transports SapM from cytoplasm to cytosol" xref: Reactome:R-HSA-9698930 "HCMV C Nucleocapsid Translocation" xref: Reactome:R-HSA-9698933 "HCMV B Nucleocapsid Translocation" is_a: GO:0022884 ! macromolecule transmembrane transporter activity is_a: GO:0140318 ! protein transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input PR:000000001 ! protein intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: part_of GO:0071806 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! protein transmembrane transport [Term] id: GO:0008324 name: monoatomic cation transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of cation from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "cation transmembrane transporter activity" BROAD [] synonym: "transmembrane cation transporter activity" EXACT [] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation relationship: has_primary_input CHEBI:23906 ! monoatomic cation relationship: part_of GO:0098655 ! monoatomic cation transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0008347 name: glial cell migration namespace: biological_process alt_id: GO:0043359 def: "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:jl, GOC:mtg_sensu] synonym: "glia cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000125 ! glial cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0042063 ! gliogenesis relationship: results_in_movement_of CL:0000125 ! glial cell [Term] id: GO:0008354 name: germ cell migration namespace: biological_process def: "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." [GOC:bf, GOC:jl] synonym: "germ-cell migration" EXACT [] synonym: "primordial germ cell migration" RELATED [] is_a: GO:0016477 ! cell migration is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000586 ! germ cell relationship: part_of GO:0007276 ! gamete generation relationship: results_in_movement_of CL:0000586 ! germ cell [Term] id: GO:0008356 name: asymmetric cell division namespace: biological_process def: "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." [PMID:11672519] synonym: "asymmetric cytokinesis" RELATED [] synonym: "asymmetrical cell division" EXACT [] synonym: "asymmetrical cytokinesis" RELATED [] xref: Wikipedia:Asymmetric_cell_division is_a: GO:0051301 ! cell division [Term] id: GO:0008358 name: maternal determination of anterior/posterior axis, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] is_a: GO:0008595 ! anterior/posterior axis specification, embryo [Term] id: GO:0008366 name: axon ensheathment namespace: biological_process alt_id: GO:0042553 def: "Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal." [GOC:jl, ISBN:0878932437] synonym: "cellular axon ensheathment" EXACT [] synonym: "cellular nerve ensheathment" RELATED [] synonym: "nerve ensheathment" RELATED [] is_a: GO:0007272 ! ensheathment of neurons relationship: has_participant GO:0030424 ! axon [Term] id: GO:0008406 name: gonad development namespace: biological_process def: "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." [GOC:ems, ISBN:0198506732] synonym: "gonadogenesis" EXACT [GOC:cjm] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000991 ! gonad relationship: part_of GO:0045137 ! development of primary sexual characteristics relationship: results_in_development_of UBERON:0000991 ! gonad [Term] id: GO:0008504 name: monoamine transmembrane transporter activity namespace: molecular_function alt_id: GO:0015201 def: "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." [GOC:mah] xref: Reactome:R-HSA-372542 "Loading of dopamine into synaptic veiscles" xref: Reactome:R-HSA-379393 "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-380586 "loading of Serotonin in synaptic vesicles" xref: Reactome:R-HSA-380620 "Reuptake of serotonin from the synapse" xref: Reactome:R-HSA-444160 "VMAT1/2 can mediate the transport of biogenic amines" xref: Reactome:R-HSA-5660706 "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol" is_a: GO:0022804 ! active transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:63534 ! monoamine relationship: has_primary_input CHEBI:63534 ! monoamine relationship: part_of GO:0015844 ! monoamine transport [Term] id: GO:0008514 name: organic anion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai] xref: Reactome:R-HSA-2142859 "Growing HA is extruded from the cell by ABCC5" xref: Reactome:R-HSA-561041 "OAT1-3 transport organic anions with antiport of dicarboxylic acids" xref: Reactome:R-HSA-9794830 "SLC22A8 transports Cipro into renal cell" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25696 ! organic anion relationship: has_primary_input CHEBI:25696 ! organic anion relationship: part_of GO:0015711 ! organic anion transport [Term] id: GO:0008544 name: epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:go_curators, UBERON:0001003] synonym: "hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0009888 ! tissue development property_value: RO:0002161 NCBITaxon:33090 [Term] id: GO:0008584 name: male gonad development namespace: biological_process def: "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." [GOC:jid] synonym: "testicular development" EXACT [GOC:sl] synonym: "testis development" EXACT [GOC:sl] is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000473 ! testis relationship: part_of GO:0046546 ! development of primary male sexual characteristics relationship: results_in_development_of UBERON:0000473 ! testis [Term] id: GO:0008585 name: female gonad development namespace: biological_process alt_id: GO:0061039 def: "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:tb] synonym: "ovarian development" RELATED [GOC:sl] synonym: "ovary development" RELATED [GOC:sl] is_a: GO:0008406 ! gonad development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000992 ! ovary relationship: part_of GO:0046545 ! development of primary female sexual characteristics relationship: results_in_development_of UBERON:0000992 ! ovary property_value: RO:0002161 NCBITaxon:3398 [Term] id: GO:0008594 name: photoreceptor cell morphogenesis namespace: biological_process def: "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." [GOC:jid, GOC:mah] synonym: "photoreceptor development" RELATED [] is_a: GO:0048667 ! cell morphogenesis involved in neuron differentiation intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000210 ! photoreceptor cell relationship: part_of GO:0042461 ! photoreceptor cell development relationship: results_in_morphogenesis_of CL:0000210 ! photoreceptor cell [Term] id: GO:0008595 name: anterior/posterior axis specification, embryo namespace: biological_process def: "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." [http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm, ISBN:0879694238] synonym: "anterior/posterior axis determination, embryo" RELATED [GOC:dph] is_a: GO:0000578 ! embryonic axis specification is_a: GO:0009948 ! anterior/posterior axis specification relationship: part_of GO:0007351 ! tripartite regional subdivision [Term] id: GO:0008610 name: lipid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid anabolism" EXACT [] synonym: "lipid biosynthesis" EXACT [] synonym: "lipid formation" EXACT [] synonym: "lipid synthesis" EXACT [] synonym: "lipogenesis" EXACT [GOC:sl] is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18059 ! lipid relationship: has_primary_output CHEBI:18059 ! lipid [Term] id: GO:0008643 name: carbohydrate transport namespace: biological_process alt_id: GO:0006861 alt_id: GO:0008644 def: "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y." [GOC:ai] subset: goslim_pir subset: goslim_yeast synonym: "sugar transport" NARROW [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16646 ! carbohydrate relationship: has_primary_input CHEBI:16646 ! carbohydrate [Term] id: GO:0008645 name: hexose transmembrane transport namespace: biological_process alt_id: GO:0008646 alt_id: GO:0008647 alt_id: GO:0035428 def: "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "hexose membrane transport" RELATED [] synonym: "hexose transport" RELATED [] synonym: "high-affinity hexose transport" NARROW [] synonym: "low-affinity hexose transport" NARROW [] is_a: GO:0015749 ! monosaccharide transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18133 ! hexose intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:18133 ! hexose created_by: bf creation_date: 2010-04-08T10:27:23Z [Term] id: GO:0008652 name: amino acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." [ISBN:0198506732] synonym: "amino acid anabolism" EXACT [] synonym: "amino acid biosynthesis" EXACT [] synonym: "amino acid formation" EXACT [] synonym: "amino acid synthesis" EXACT [] synonym: "cellular amino acid biosynthetic process" EXACT [] xref: Wikipedia:Amino_acid_synthesis is_a: GO:0006520 ! amino acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:37022 ! amino-acid anion relationship: has_primary_output CHEBI:37022 ! amino-acid anion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0009056 name: catabolic process namespace: biological_process alt_id: GO:0044243 alt_id: GO:0044712 def: "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." [ISBN:0198547684] subset: goslim_agr subset: goslim_chembl subset: goslim_plant synonym: "breakdown" EXACT [] synonym: "catabolism" EXACT [] synonym: "degradation" EXACT [] synonym: "multicellular organismal catabolic process" NARROW [] synonym: "single-organism catabolic process" RELATED [] xref: Wikipedia:Catabolism is_a: GO:0008152 ! metabolic process created_by: jl creation_date: 2012-10-17T15:52:35Z [Term] id: GO:0009057 name: macromolecule catabolic process namespace: biological_process alt_id: GO:0043285 alt_id: GO:0044266 def: "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: goslim_pir synonym: "biopolymer catabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "cellular macromolecule catabolic process" RELATED [] synonym: "cellular macromolecule catabolism" RELATED [] synonym: "cellular macromolecule degradation" RELATED [] synonym: "macromolecule breakdown" EXACT [] synonym: "macromolecule catabolism" EXACT [] synonym: "macromolecule degradation" EXACT [] synonym: "multicellular organismal macromolecule catabolic process" NARROW [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule relationship: has_primary_input CHEBI:33694 ! biomacromolecule [Term] id: GO:0009058 name: biosynthetic process namespace: biological_process alt_id: GO:0044274 alt_id: GO:0044711 def: "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." [GOC:curators, ISBN:0198547684] subset: goslim_chembl subset: goslim_metagenomics subset: goslim_plant synonym: "anabolism" EXACT [] synonym: "biosynthesis" EXACT [] synonym: "formation" BROAD [] synonym: "multicellular organismal biosynthetic process" NARROW [] synonym: "single-organism biosynthetic process" RELATED [] synonym: "synthesis" EXACT [] xref: Wikipedia:Anabolism is_a: GO:0008152 ! metabolic process created_by: jl creation_date: 2012-10-17T15:52:18Z [Term] id: GO:0009059 name: macromolecule biosynthetic process namespace: biological_process alt_id: GO:0043284 def: "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: goslim_pir synonym: "biopolymer biosynthetic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule anabolism" EXACT [] synonym: "macromolecule biosynthesis" EXACT [] synonym: "macromolecule formation" EXACT [] synonym: "macromolecule synthesis" EXACT [] is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33694 ! biomacromolecule relationship: has_primary_output CHEBI:33694 ! biomacromolecule property_value: IAO:0000233 "http://amigo.geneontology.org/amigo/term/GO:0070589" xsd:anyURI [Term] id: GO:0009063 name: amino acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." [GOC:ai] synonym: "amino acid breakdown" EXACT [] synonym: "amino acid catabolism" EXACT [] synonym: "amino acid degradation" EXACT [] synonym: "cellular amino acid catabolic process" EXACT [] is_a: GO:0006520 ! amino acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:37022 ! amino-acid anion relationship: has_primary_input CHEBI:37022 ! amino-acid anion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17904" xsd:anyURI [Term] id: GO:0009100 name: glycoprotein metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] subset: goslim_drosophila synonym: "glycoprotein metabolism" EXACT [] is_a: GO:0019538 ! protein metabolic process is_a: GO:1901135 ! carbohydrate derivative metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:17089 ! glycoprotein relationship: has_primary_input_or_output CHEBI:17089 ! glycoprotein [Term] id: GO:0009101 name: glycoprotein biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:go_curators, ISBN:0198506732] synonym: "glycoprotein anabolism" EXACT [] synonym: "glycoprotein biosynthesis" EXACT [] synonym: "glycoprotein formation" EXACT [] synonym: "glycoprotein synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0009100 ! glycoprotein metabolic process is_a: GO:1901137 ! carbohydrate derivative biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:17089 ! glycoprotein relationship: has_primary_output CHEBI:17089 ! glycoprotein [Term] id: GO:0009112 name: nucleobase metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." [GOC:ma] synonym: "nucleobase metabolism" EXACT [] is_a: GO:0055086 ! nucleobase-containing small molecule metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18282 ! nucleobase relationship: has_primary_input_or_output CHEBI:18282 ! nucleobase [Term] id: GO:0009250 name: glucan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan anabolism" EXACT [] synonym: "glucan biosynthesis" EXACT [] synonym: "glucan formation" EXACT [] synonym: "glucan synthesis" EXACT [] is_a: GO:0000271 ! polysaccharide biosynthetic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:37163 ! glucan relationship: has_primary_output CHEBI:37163 ! glucan [Term] id: GO:0009251 name: glucan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." [GOC:go_curators] synonym: "glucan breakdown" EXACT [] synonym: "glucan catabolism" EXACT [] synonym: "glucan degradation" EXACT [] is_a: GO:0000272 ! polysaccharide catabolic process is_a: GO:0044042 ! glucan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:37163 ! glucan relationship: has_primary_input CHEBI:37163 ! glucan [Term] id: GO:0009306 name: protein secretion namespace: biological_process alt_id: GO:0045166 alt_id: GO:0045731 def: "The controlled release of proteins from a cell." [GOC:ai] synonym: "glycoprotein secretion" NARROW [] synonym: "protein secretion during cell fate commitment" NARROW [] synonym: "protein secretion resulting in cell fate commitment" NARROW [] is_a: GO:0015031 ! protein transport is_a: GO:0032940 ! secretion by cell is_a: GO:0035592 ! establishment of protein localization to extracellular region intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input PR:000000001 ! protein [Term] id: GO:0009308 name: amine metabolic process namespace: biological_process alt_id: GO:0044106 def: "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] subset: goslim_chembl subset: goslim_pir synonym: "amine metabolism" EXACT [] synonym: "cellular amine metabolic process" EXACT [] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:32952 ! amine relationship: has_primary_input_or_output CHEBI:32952 ! amine created_by: jl creation_date: 2009-07-15T11:55:44Z [Term] id: GO:0009309 name: amine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine anabolism" EXACT [] synonym: "amine biosynthesis" EXACT [] synonym: "amine formation" EXACT [] synonym: "amine synthesis" EXACT [] is_a: GO:0009308 ! amine metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:32952 ! amine relationship: has_primary_output CHEBI:32952 ! amine [Term] id: GO:0009310 name: amine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." [GOC:jl, ISBN:0198506732] synonym: "amine breakdown" EXACT [] synonym: "amine catabolism" EXACT [] synonym: "amine degradation" EXACT [] is_a: GO:0009308 ! amine metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:32952 ! amine relationship: has_primary_input CHEBI:32952 ! amine [Term] id: GO:0009314 name: response to radiation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." [GOC:jl, Wikipedia:Electromagnetic_radiation] comment: Note that 'radiation' refers to electromagnetic radiation of any wavelength. synonym: "response to electromagnetic radiation stimulus" EXACT [] synonym: "response to radiation stimulus" EXACT [] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0009416 name: response to light stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." [GOC:go_curators, ISBN:0582227089] subset: goslim_plant is_a: GO:0009314 ! response to radiation intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:30212 ! photon relationship: has_input CHEBI:30212 ! photon [Term] id: GO:0009566 name: fertilization namespace: biological_process def: "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:tb, ISBN:0198506732] synonym: "syngamy" EXACT [] xref: Wikipedia:Fertilisation is_a: GO:0022414 ! reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: results_in_formation_of CL:0010017 ! zygote intersection_of: results_in_fusion_of GO:0043073 ! germ cell nucleus relationship: part_of GO:0019953 ! sexual reproduction relationship: results_in_formation_of CL:0010017 ! zygote relationship: results_in_fusion_of GO:0043073 ! germ cell nucleus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20176" xsd:anyURI [Term] id: GO:0009581 name: detection of external stimulus namespace: biological_process def: "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." [GOC:hb] synonym: "perception of external stimulus" RELATED [] is_a: GO:0009605 ! response to external stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009582 name: detection of abiotic stimulus namespace: biological_process def: "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." [GOC:hb] synonym: "perception of abiotic stimulus" RELATED [] is_a: GO:0009628 ! response to abiotic stimulus is_a: GO:0051606 ! detection of stimulus [Term] id: GO:0009583 name: detection of light stimulus namespace: biological_process def: "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." [GOC:go_curators] synonym: "detection of light" EXACT [] synonym: "perception of light" RELATED [] is_a: GO:0009416 ! response to light stimulus is_a: GO:0009581 ! detection of external stimulus is_a: GO:0009582 ! detection of abiotic stimulus [Term] id: GO:0009584 name: detection of visible light namespace: biological_process def: "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." [GOC:go_curators, ISBN:0198506732] synonym: "perception of visible light" RELATED [] is_a: GO:0009583 ! detection of light stimulus [Term] id: GO:0009593 name: detection of chemical stimulus namespace: biological_process def: "The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal." [GOC:jl] synonym: "chemoperception" EXACT [] synonym: "chemoreception" RELATED [] synonym: "detection of chemical substance" EXACT [] synonym: "perception of chemical stimulus" RELATED [] synonym: "perception of chemical substance" RELATED [] is_a: GO:0051606 ! detection of stimulus relationship: part_of GO:0042221 ! response to chemical [Term] id: GO:0009605 name: response to external stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_drosophila subset: goslim_plant synonym: "response to environmental stimulus" EXACT [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009607 name: response to biotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_metagenomics subset: goslim_plant synonym: "response to biotic stress" NARROW [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009612 name: response to mechanical stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus." [GOC:hb] synonym: "chemi-mechanical coupling" RELATED [] synonym: "mechanical stimulus response" EXACT [] is_a: GO:0009605 ! response to external stimulus is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0009617 name: response to bacterium namespace: biological_process alt_id: GO:0009618 alt_id: GO:0009680 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium." [GOC:hb] synonym: "response to bacteria" EXACT [] is_a: GO:0051707 ! response to other organism intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input NCBITaxon:2 ! Bacteria relationship: has_input NCBITaxon:2 ! Bacteria [Term] id: GO:0009620 name: response to fungus namespace: biological_process alt_id: GO:0009621 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." [GOC:hb] synonym: "response to fungi" EXACT [] is_a: GO:0051707 ! response to other organism intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input NCBITaxon:4751 ! Fungi relationship: has_input NCBITaxon:4751 ! Fungi [Term] id: GO:0009628 name: response to abiotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." [GOC:hb] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_metagenomics subset: goslim_plant synonym: "response to abiotic stress" NARROW [] is_a: GO:0050896 ! response to stimulus property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16572" xsd:anyURI [Term] id: GO:0009636 name: response to toxic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:lr] subset: goslim_chembl synonym: "detoxification response" NARROW [] synonym: "toxin resistance" RELATED [] synonym: "toxin susceptibility/resistance" RELATED [] is_a: GO:0042221 ! response to chemical [Term] id: GO:0009653 name: anatomical structure morphogenesis namespace: biological_process def: "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." [GOC:go_curators, ISBN:0521436125] synonym: "anatomical structure organization" EXACT [] synonym: "embryogenesis and morphogenesis" BROAD [] synonym: "morphogenesis" EXACT [] xref: Wikipedia:Morphogenesis is_a: GO:0032502 ! developmental process disjoint_from: GO:0048856 ! anatomical structure development disjoint_from: GO:0071695 ! anatomical structure maturation relationship: part_of GO:0048856 ! anatomical structure development [Term] id: GO:0009712 name: catechol-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." [GOC:sm, ISBN:0198547684] synonym: "catechol metabolic process" RELATED [] synonym: "catechol metabolism" RELATED [] is_a: GO:0018958 ! phenol-containing compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33566 ! catechols relationship: has_primary_input_or_output CHEBI:33566 ! catechols [Term] id: GO:0009713 name: catechol-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] synonym: "catechol anabolism" RELATED [] synonym: "catechol biosynthesis" RELATED [] synonym: "catechol biosynthetic process" RELATED [] synonym: "catechol formation" RELATED [] synonym: "catechol synthesis" RELATED [] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0046189 ! phenol-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33566 ! catechols relationship: has_primary_output CHEBI:33566 ! catechols [Term] id: GO:0009719 name: response to endogenous stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." [GOC:sm] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_plant is_a: GO:0050896 ! response to stimulus [Term] id: GO:0009725 name: response to hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." [GOC:jl] synonym: "growth regulator" RELATED [] synonym: "response to hormone stimulus" EXACT [GOC:dos] is_a: GO:0009719 ! response to endogenous stimulus is_a: GO:0010033 ! response to organic substance [Term] id: GO:0009743 name: response to carbohydrate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." [GOC:jl] synonym: "response to carbohydrate stimulus" EXACT [GOC:dos] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:16646 ! carbohydrate relationship: has_input CHEBI:16646 ! carbohydrate [Term] id: GO:0009746 name: response to hexose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." [GOC:jl] synonym: "response to hexose stimulus" EXACT [GOC:dos] is_a: GO:0034284 ! response to monosaccharide intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:18133 ! hexose relationship: has_input CHEBI:18133 ! hexose [Term] id: GO:0009749 name: response to glucose namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." [GOC:jl] synonym: "response to glucose stimulus" EXACT [GOC:dos] is_a: GO:0009746 ! response to hexose intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:17234 ! glucose relationship: has_input CHEBI:17234 ! glucose [Term] id: GO:0009786 name: regulation of asymmetric cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of asymmetric cell division." [GOC:lr] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008356 ! asymmetric cell division relationship: regulates GO:0008356 ! asymmetric cell division [Term] id: GO:0009790 name: embryo development namespace: biological_process alt_id: GO:0009795 def: "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] subset: gocheck_do_not_manually_annotate subset: goslim_chembl subset: goslim_plant synonym: "embryogenesis" EXACT [] synonym: "embryogenesis and morphogenesis" BROAD [] synonym: "embryonal development" EXACT [] xref: Wikipedia:Embryogenesis is_a: GO:0007275 ! multicellular organism development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000922 ! embryo relationship: results_in_development_of UBERON:0000922 ! embryo [Term] id: GO:0009791 name: post-embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." [GOC:go_curators] subset: goslim_plant is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0009792 name: embryo development ending in birth or egg hatching namespace: biological_process def: "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." [GOC:go_curators, GOC:isa_complete, GOC:mtg_sensu] synonym: "embryogenesis" BROAD [] is_a: GO:0009790 ! embryo development relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0009798 name: axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of a pattern along a line or around a point." [GOC:dph, GOC:go_curators, GOC:isa_complete] synonym: "axis determination" RELATED [] is_a: GO:0007389 ! pattern specification process [Term] id: GO:0009820 name: alkaloid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] subset: goslim_chembl synonym: "alkaloid metabolism" EXACT [] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:22315 ! alkaloid relationship: has_primary_input_or_output CHEBI:22315 ! alkaloid [Term] id: GO:0009821 name: alkaloid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid anabolism" EXACT [] synonym: "alkaloid biosynthesis" EXACT [] synonym: "alkaloid formation" EXACT [] synonym: "alkaloid synthesis" EXACT [] xref: UM-BBD_enzymeID:e0711 is_a: GO:0009820 ! alkaloid metabolic process is_a: GO:0044550 ! secondary metabolite biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:22315 ! alkaloid relationship: has_primary_output CHEBI:22315 ! alkaloid [Term] id: GO:0009822 name: alkaloid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." [GOC:lr, ISBN:0122146743] synonym: "alkaloid breakdown" EXACT [] synonym: "alkaloid catabolism" EXACT [] synonym: "alkaloid degradation" EXACT [] is_a: GO:0009820 ! alkaloid metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:22315 ! alkaloid relationship: has_primary_input CHEBI:22315 ! alkaloid [Term] id: GO:0009880 name: embryonic pattern specification namespace: biological_process def: "The process that results in the patterns of cell differentiation that will arise in an embryo." [GOC:go_curators, ISBN:0521436125] synonym: "embryonic pattern biosynthesis" BROAD [] synonym: "embryonic pattern formation" BROAD [] synonym: "ventral/lateral system" RELATED [] is_a: GO:0007389 ! pattern specification process relationship: part_of GO:0009790 ! embryo development [Term] id: GO:0009887 name: animal organ morphogenesis namespace: biological_process def: "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544] synonym: "histogenesis and organogenesis" BROAD [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000062 ! organ relationship: part_of GO:0048513 ! animal organ development relationship: results_in_morphogenesis_of UBERON:0000062 ! organ [Term] id: GO:0009888 name: tissue development namespace: biological_process def: "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." [ISBN:0471245208] synonym: "histogenesis" EXACT [] synonym: "histogenesis and organogenesis" BROAD [] xref: Wikipedia:Histogenesis is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000479 ! tissue relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: results_in_development_of UBERON:0000479 ! tissue property_value: RO:0002161 NCBITaxon:147554 property_value: RO:0002161 NCBITaxon:33630 property_value: RO:0002161 NCBITaxon:33682 property_value: RO:0002161 NCBITaxon:38254 property_value: RO:0002161 NCBITaxon:4891 [Term] id: GO:0009889 name: regulation of biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "regulation of anabolism" EXACT [] synonym: "regulation of biosynthesis" EXACT [] synonym: "regulation of formation" EXACT [] synonym: "regulation of synthesis" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009058 ! biosynthetic process relationship: regulates GO:0009058 ! biosynthetic process [Term] id: GO:0009890 name: negative regulation of biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "down regulation of biosynthetic process" EXACT [] synonym: "down-regulation of biosynthetic process" EXACT [] synonym: "downregulation of biosynthetic process" EXACT [] synonym: "inhibition of biosynthetic process" NARROW [] synonym: "negative regulation of anabolism" EXACT [] synonym: "negative regulation of biosynthesis" EXACT [] synonym: "negative regulation of formation" EXACT [] synonym: "negative regulation of synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009058 ! biosynthetic process relationship: negatively_regulates GO:0009058 ! biosynthetic process [Term] id: GO:0009891 name: positive regulation of biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." [GOC:go_curators] synonym: "activation of biosynthetic process" NARROW [] synonym: "positive regulation of anabolism" EXACT [] synonym: "positive regulation of biosynthesis" EXACT [] synonym: "positive regulation of formation" EXACT [] synonym: "positive regulation of synthesis" EXACT [] synonym: "stimulation of biosynthetic process" NARROW [] synonym: "up regulation of biosynthetic process" EXACT [] synonym: "up-regulation of biosynthetic process" EXACT [] synonym: "upregulation of biosynthetic process" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009058 ! biosynthetic process relationship: positively_regulates GO:0009058 ! biosynthetic process [Term] id: GO:0009892 name: negative regulation of metabolic process namespace: biological_process alt_id: GO:0044252 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "down regulation of metabolic process" EXACT [] synonym: "down-regulation of metabolic process" EXACT [] synonym: "downregulation of metabolic process" EXACT [] synonym: "inhibition of metabolic process" NARROW [] synonym: "inhibition of organismal metabolic process" NARROW [] synonym: "negative regulation of metabolism" EXACT [] synonym: "negative regulation of multicellular organismal metabolic process" NARROW [] synonym: "negative regulation of organismal metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008152 ! metabolic process relationship: negatively_regulates GO:0008152 ! metabolic process [Term] id: GO:0009893 name: positive regulation of metabolic process namespace: biological_process alt_id: GO:0044253 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] synonym: "activation of metabolic process" NARROW [] synonym: "positive regulation of metabolism" EXACT [] synonym: "positive regulation of multicellular organismal metabolic process" NARROW [] synonym: "positive regulation of organismal metabolism" NARROW [] synonym: "stimulation of metabolic process" NARROW [] synonym: "stimulation of organismal metabolic process" NARROW [] synonym: "up regulation of metabolic process" EXACT [] synonym: "up-regulation of metabolic process" EXACT [] synonym: "up-regulation of organismal metabolic process" NARROW [] synonym: "upregulation of metabolic process" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008152 ! metabolic process relationship: positively_regulates GO:0008152 ! metabolic process [Term] id: GO:0009894 name: regulation of catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "regulation of breakdown" EXACT [] synonym: "regulation of catabolism" EXACT [] synonym: "regulation of degradation" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009056 ! catabolic process relationship: regulates GO:0009056 ! catabolic process [Term] id: GO:0009895 name: negative regulation of catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "down regulation of catabolic process" EXACT [] synonym: "down-regulation of catabolic process" EXACT [] synonym: "downregulation of catabolic process" EXACT [] synonym: "inhibition of catabolic process" NARROW [] synonym: "negative regulation of breakdown" EXACT [] synonym: "negative regulation of catabolism" EXACT [] synonym: "negative regulation of degradation" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009056 ! catabolic process relationship: negatively_regulates GO:0009056 ! catabolic process [Term] id: GO:0009896 name: positive regulation of catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." [GOC:go_curators] synonym: "activation of catabolic process" NARROW [] synonym: "positive regulation of breakdown" EXACT [] synonym: "positive regulation of catabolism" EXACT [] synonym: "positive regulation of degradation" EXACT [] synonym: "stimulation of catabolic process" NARROW [] synonym: "up regulation of catabolic process" EXACT [] synonym: "up-regulation of catabolic process" EXACT [] synonym: "upregulation of catabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009056 ! catabolic process relationship: positively_regulates GO:0009056 ! catabolic process [Term] id: GO:0009913 name: epidermal cell differentiation namespace: biological_process alt_id: GO:0043355 def: "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." [GOC:dph, GOC:go_curators, GOC:mtg_sensu, GOC:sdb_2009, GOC:tb] synonym: "hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000362 ! epidermal cell relationship: part_of GO:0008544 ! epidermis development relationship: results_in_acquisition_of_features_of CL:0000362 ! epidermal cell [Term] id: GO:0009914 name: hormone transport namespace: biological_process def: "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:tb] subset: goslim_pir is_a: GO:0006810 ! transport is_a: GO:0010817 ! regulation of hormone levels [Term] id: GO:0009948 name: anterior/posterior axis specification namespace: biological_process def: "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "anterior/posterior axis determination" RELATED [GOC:dph] is_a: GO:0009798 ! axis specification relationship: part_of GO:0009952 ! anterior/posterior pattern specification [Term] id: GO:0009952 name: anterior/posterior pattern specification namespace: biological_process def: "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." [GOC:dph, GOC:go_curators, GOC:isa_complete, GOC:tb] synonym: "anterior/posterior pattern formation" RELATED [] is_a: GO:0003002 ! regionalization [Term] id: GO:0009966 name: regulation of signal transduction namespace: biological_process alt_id: GO:0035466 def: "Any process that modulates the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "regulation of signaling pathway" RELATED [] synonym: "regulation of signalling pathway" RELATED [GOC:mah] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007165 ! signal transduction relationship: regulates GO:0007165 ! signal transduction [Term] id: GO:0009967 name: positive regulation of signal transduction namespace: biological_process alt_id: GO:0035468 def: "Any process that activates or increases the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "activation of signal transduction" NARROW [] synonym: "positive regulation of signaling pathway" RELATED [] synonym: "positive regulation of signalling pathway" RELATED [GOC:mah] synonym: "stimulation of signal transduction" NARROW [] synonym: "up regulation of signal transduction" EXACT [] synonym: "up-regulation of signal transduction" EXACT [] synonym: "upregulation of signal transduction" EXACT [] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007165 ! signal transduction relationship: positively_regulates GO:0007165 ! signal transduction [Term] id: GO:0009968 name: negative regulation of signal transduction namespace: biological_process alt_id: GO:0035467 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." [GOC:sm] synonym: "down regulation of signal transduction" EXACT [] synonym: "down-regulation of signal transduction" EXACT [] synonym: "downregulation of signal transduction" EXACT [] synonym: "inhibition of signal transduction" NARROW [] synonym: "negative regulation of signaling pathway" RELATED [] synonym: "negative regulation of signalling pathway" RELATED [GOC:mah] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007165 ! signal transduction relationship: negatively_regulates GO:0007165 ! signal transduction [Term] id: GO:0009987 name: cellular process namespace: biological_process alt_id: GO:0008151 alt_id: GO:0044763 alt_id: GO:0050875 def: "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators, GOC:isa_complete] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate subset: goslim_plant synonym: "cell growth and/or maintenance" NARROW [] synonym: "cell physiology" EXACT [] synonym: "cellular physiological process" EXACT [] synonym: "single-organism cellular process" RELATED [] is_a: GO:0008150 ! biological_process created_by: jl creation_date: 2012-12-11T16:56:55Z [Term] id: GO:0009994 name: oocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." [GOC:go_curators, GOC:mtg_sensu] synonym: "oocyte cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000023 ! oocyte relationship: part_of GO:0048477 ! oogenesis relationship: results_in_acquisition_of_features_of CL:0000023 ! oocyte [Term] id: GO:0010001 name: glial cell differentiation namespace: biological_process alt_id: GO:0007404 alt_id: GO:0043360 def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." [GOC:go_curators, GOC:mtg_sensu] synonym: "glia cell differentiation" EXACT [] synonym: "neuroglia differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000125 ! glial cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0042063 ! gliogenesis relationship: results_in_acquisition_of_features_of CL:0000125 ! glial cell [Term] id: GO:0010002 name: cardioblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:go_curators] synonym: "cardiac precursor cell differentiation" EXACT [GOC:mtg_heart] synonym: "cardioblast cell differentiation" EXACT [] synonym: "cardiomyocyte generation" RELATED [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002664 ! cardioblast relationship: results_in_acquisition_of_features_of CL:0002664 ! cardioblast [Term] id: GO:0010032 name: meiotic chromosome condensation namespace: biological_process def: "Compaction of chromatin structure prior to meiosis in eukaryotic cells." [PMID:10072401] synonym: "chromosome condensation involved in meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0030261 ! chromosome condensation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0030261 ! chromosome condensation intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0010033 name: response to organic substance namespace: biological_process alt_id: GO:1990367 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." [GOC:sm, PMID:23356676] synonym: "process resulting in tolerance to organic substance" NARROW [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0042221 ! response to chemical intersection_of: has_input CHEBI:50860 ! organic molecular entity relationship: has_input CHEBI:50860 ! organic molecular entity [Term] id: GO:0010034 name: response to acetate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." [GOC:sm] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:30089 ! acetate relationship: has_input CHEBI:30089 ! acetate [Term] id: GO:0010035 name: response to inorganic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." [GOC:sm] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:24835 ! inorganic molecular entity relationship: has_input CHEBI:24835 ! inorganic molecular entity [Term] id: GO:0010038 name: response to metal ion namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." [GOC:sm] synonym: "heavy metal sensitivity/resistance" RELATED [] synonym: "response to heavy metal" NARROW [] synonym: "response to metal" EXACT [] is_a: GO:0010035 ! response to inorganic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:25213 ! metal cation relationship: has_input CHEBI:25213 ! metal cation [Term] id: GO:0010070 name: zygote asymmetric cell division namespace: biological_process def: "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." [GOC:tb] synonym: "zygote asymmetric cytokinesis" RELATED [] is_a: GO:0008356 ! asymmetric cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_input CL:0000365 ! animal zygote relationship: has_input CL:0000365 ! animal zygote [Term] id: GO:0010160 name: formation of animal organ boundary namespace: biological_process alt_id: GO:0048862 def: "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." [GOC:dph, GOC:isa_complete, PMID:9611175] synonym: "organ boundary specification" EXACT [] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048859 ! formation of anatomical boundary intersection_of: occurs_in UBERON:0000062 ! organ relationship: occurs_in UBERON:0000062 ! organ relationship: part_of GO:0048645 ! animal organ formation [Term] id: GO:0010171 name: body morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the soma are generated and organized." [GOC:ems, ISBN:0140512888] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000468 ! multicellular organism relationship: results_in_morphogenesis_of UBERON:0000468 ! multicellular organism [Term] id: GO:0010243 name: response to organonitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." [PMID:9869419] synonym: "response to organic nitrogen" EXACT [] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:35352 ! organonitrogen compound relationship: has_input CHEBI:35352 ! organonitrogen compound [Term] id: GO:0010256 name: endomembrane system organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." [GOC:mah, GOC:sm] subset: goslim_drosophila synonym: "endomembrane organization" EXACT [] synonym: "endomembrane system organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0012505 ! endomembrane system relationship: results_in_organization_of GO:0012505 ! endomembrane system [Term] id: GO:0010453 name: regulation of cell fate commitment namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045165 ! cell fate commitment relationship: regulates GO:0045165 ! cell fate commitment [Term] id: GO:0010454 name: negative regulation of cell fate commitment namespace: biological_process def: "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045165 ! cell fate commitment relationship: negatively_regulates GO:0045165 ! cell fate commitment [Term] id: GO:0010455 name: positive regulation of cell fate commitment namespace: biological_process def: "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." [GOC:dph, GOC:tb] is_a: GO:0010453 ! regulation of cell fate commitment is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045165 ! cell fate commitment relationship: positively_regulates GO:0045165 ! cell fate commitment [Term] id: GO:0010463 name: mesenchymal cell proliferation namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0008019 ! mesenchymal cell relationship: acts_on_population_of CL:0008019 ! mesenchymal cell [Term] id: GO:0010464 name: regulation of mesenchymal cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010463 ! mesenchymal cell proliferation relationship: regulates GO:0010463 ! mesenchymal cell proliferation [Term] id: GO:0010467 name: gene expression namespace: biological_process def: "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, translation and maturation for protein-coding genes." [GOC:txnOH-2018, PMID:25934543, PMID:31580950] subset: goslim_flybase_ribbon xref: Wikipedia:Gene_expression is_a: GO:0043170 ! macromolecule metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010468 name: regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] comment: This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation. synonym: "gene regulation" RELATED [GOC:cjm] synonym: "regulation of gene product expression" RELATED [] synonym: "regulation of protein expression" NARROW [] xref: Wikipedia:Regulation_of_gene_expression is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010467 ! gene expression relationship: regulates GO:0010467 ! gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010470 name: regulation of gastrulation namespace: biological_process def: "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0045995 ! regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007369 ! gastrulation relationship: regulates GO:0007369 ! gastrulation [Term] id: GO:0010481 name: epidermal cell division namespace: biological_process def: "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." [PMID:17450124] synonym: "hypodermal cell division" RELATED [GOC:kmv, GOC:rk] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000362 ! epidermal cell relationship: has_input CL:0000362 ! epidermal cell [Term] id: GO:0010482 name: regulation of epidermal cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." [PMID:17450124] synonym: "regulation of hypodermal cell division" RELATED [GOC:kmv, GOC:rk] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010481 ! epidermal cell division relationship: regulates GO:0010481 ! epidermal cell division [Term] id: GO:0010496 name: intercellular transport namespace: biological_process alt_id: GO:1902585 def: "The movement of substances between cells." [GOC:dhl] synonym: "single organism intercellular transport" RELATED [GOC:TermGenie] synonym: "single-organism intercellular transport" RELATED [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location CL:0000000 ! cell intersection_of: has_target_start_location CL:0000000 ! cell intersection_of: results_in_transport_across GO:0005615 ! extracellular space relationship: has_target_end_location CL:0000000 ! cell relationship: has_target_start_location CL:0000000 ! cell relationship: results_in_transport_across GO:0005615 ! extracellular space created_by: jl creation_date: 2013-12-19T13:24:56Z [Term] id: GO:0010549 name: regulation of membrane disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of membrane disassembly." [GOC:dph, GOC:tb] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030397 ! membrane disassembly relationship: regulates GO:0030397 ! membrane disassembly [Term] id: GO:0010556 name: regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009059 ! macromolecule biosynthetic process relationship: regulates GO:0009059 ! macromolecule biosynthetic process [Term] id: GO:0010557 name: positive regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010604 ! positive regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009059 ! macromolecule biosynthetic process relationship: positively_regulates GO:0009059 ! macromolecule biosynthetic process [Term] id: GO:0010558 name: negative regulation of macromolecule biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0010605 ! negative regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009059 ! macromolecule biosynthetic process relationship: negatively_regulates GO:0009059 ! macromolecule biosynthetic process [Term] id: GO:0010559 name: regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009101 ! glycoprotein biosynthetic process relationship: regulates GO:0009101 ! glycoprotein biosynthetic process [Term] id: GO:0010560 name: positive regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903020 ! positive regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009101 ! glycoprotein biosynthetic process relationship: positively_regulates GO:0009101 ! glycoprotein biosynthetic process [Term] id: GO:0010561 name: negative regulation of glycoprotein biosynthetic process namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." [GOC:dph, GOC:tb] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process is_a: GO:1903019 ! negative regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process relationship: negatively_regulates GO:0009101 ! glycoprotein biosynthetic process [Term] id: GO:0010562 name: positive regulation of phosphorus metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006793 ! phosphorus metabolic process relationship: positively_regulates GO:0006793 ! phosphorus metabolic process [Term] id: GO:0010563 name: negative regulation of phosphorus metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:dph, GOC:tb] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006793 ! phosphorus metabolic process relationship: negatively_regulates GO:0006793 ! phosphorus metabolic process [Term] id: GO:0010564 name: regulation of cell cycle process namespace: biological_process def: "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022402 ! cell cycle process relationship: regulates GO:0022402 ! cell cycle process [Term] id: GO:0010565 name: regulation of cellular ketone metabolic process namespace: biological_process def: "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:dph, GOC:tb] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042180 ! cellular ketone metabolic process relationship: regulates GO:0042180 ! cellular ketone metabolic process [Term] id: GO:0010566 name: regulation of ketone biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042181 ! ketone biosynthetic process relationship: regulates GO:0042181 ! ketone biosynthetic process [Term] id: GO:0010567 name: regulation of ketone catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." [GOC:dph, GOC:tb] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042182 ! ketone catabolic process relationship: regulates GO:0042182 ! ketone catabolic process [Term] id: GO:0010594 name: regulation of endothelial cell migration namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043542 ! endothelial cell migration relationship: regulates GO:0043542 ! endothelial cell migration [Term] id: GO:0010595 name: positive regulation of endothelial cell migration namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0010634 ! positive regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043542 ! endothelial cell migration relationship: positively_regulates GO:0043542 ! endothelial cell migration [Term] id: GO:0010596 name: negative regulation of endothelial cell migration namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010594 ! regulation of endothelial cell migration is_a: GO:0010633 ! negative regulation of epithelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043542 ! endothelial cell migration relationship: negatively_regulates GO:0043542 ! endothelial cell migration [Term] id: GO:0010604 name: positive regulation of macromolecule metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043170 ! macromolecule metabolic process relationship: positively_regulates GO:0043170 ! macromolecule metabolic process [Term] id: GO:0010605 name: negative regulation of macromolecule metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043170 ! macromolecule metabolic process relationship: negatively_regulates GO:0043170 ! macromolecule metabolic process [Term] id: GO:0010608 name: post-transcriptional regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." [GOC:dph, GOC:tb] synonym: "posttranscriptional regulation of gene expression" EXACT [] is_a: GO:0010468 ! regulation of gene expression [Term] id: GO:0010611 name: regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:dph, GOC:tb] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003300 ! cardiac muscle hypertrophy relationship: regulates GO:0003300 ! cardiac muscle hypertrophy [Term] id: GO:0010612 name: regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:dph, GOC:tb] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014887 ! cardiac muscle adaptation relationship: regulates GO:0014887 ! cardiac muscle adaptation [Term] id: GO:0010613 name: positive regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014742 ! positive regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003300 ! cardiac muscle hypertrophy relationship: positively_regulates GO:0003300 ! cardiac muscle hypertrophy [Term] id: GO:0010614 name: negative regulation of cardiac muscle hypertrophy namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010611 ! regulation of cardiac muscle hypertrophy is_a: GO:0014741 ! negative regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy relationship: negatively_regulates GO:0003300 ! cardiac muscle hypertrophy [Term] id: GO:0010615 name: positive regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014744 ! positive regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014887 ! cardiac muscle adaptation relationship: positively_regulates GO:0014887 ! cardiac muscle adaptation [Term] id: GO:0010616 name: negative regulation of cardiac muscle adaptation namespace: biological_process def: "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010612 ! regulation of cardiac muscle adaptation is_a: GO:0014745 ! negative regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014887 ! cardiac muscle adaptation relationship: negatively_regulates GO:0014887 ! cardiac muscle adaptation [Term] id: GO:0010623 name: programmed cell death involved in cell development namespace: biological_process def: "The activation of endogenous cellular processes that result in the death of a cell as part of its development." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] comment: This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure. synonym: "developmental programmed cell death" BROAD [] synonym: "programmed cell death involved in development" BROAD [] is_a: GO:0012501 ! programmed cell death is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0012501 ! programmed cell death intersection_of: part_of GO:0048468 ! cell development relationship: part_of GO:0048468 ! cell development [Term] id: GO:0010624 name: regulation of Schwann cell proliferation namespace: biological_process def: "Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014010 ! Schwann cell proliferation relationship: regulates GO:0014010 ! Schwann cell proliferation [Term] id: GO:0010625 name: positive regulation of Schwann cell proliferation namespace: biological_process def: "Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0010624 ! regulation of Schwann cell proliferation is_a: GO:0060252 ! positive regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014010 ! Schwann cell proliferation relationship: positively_regulates GO:0014010 ! Schwann cell proliferation [Term] id: GO:0010626 name: negative regulation of Schwann cell proliferation namespace: biological_process def: "Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0010624 ! regulation of Schwann cell proliferation is_a: GO:0060253 ! negative regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014010 ! Schwann cell proliferation relationship: negatively_regulates GO:0014010 ! Schwann cell proliferation [Term] id: GO:0010628 name: positive regulation of gene expression namespace: biological_process def: "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010604 ! positive regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010467 ! gene expression relationship: positively_regulates GO:0010467 ! gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010629 name: negative regulation of gene expression namespace: biological_process def: "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." [GOC:txnOH-2018] comment: This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation. synonym: "gene silencing" RELATED [] is_a: GO:0010468 ! regulation of gene expression is_a: GO:0010605 ! negative regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010467 ! gene expression relationship: negatively_regulates GO:0010467 ! gene expression property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22557" xsd:anyURI [Term] id: GO:0010631 name: epithelial cell migration namespace: biological_process def: "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:ascb_2009, GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000066 ! epithelial cell relationship: part_of GO:0090132 ! epithelium migration relationship: results_in_movement_of CL:0000066 ! epithelial cell [Term] id: GO:0010632 name: regulation of epithelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0030334 ! regulation of cell migration is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010631 ! epithelial cell migration relationship: regulates GO:0010631 ! epithelial cell migration [Term] id: GO:0010633 name: negative regulation of epithelial cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010631 ! epithelial cell migration relationship: negatively_regulates GO:0010631 ! epithelial cell migration [Term] id: GO:0010634 name: positive regulation of epithelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010632 ! regulation of epithelial cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010631 ! epithelial cell migration relationship: positively_regulates GO:0010631 ! epithelial cell migration [Term] id: GO:0010638 name: positive regulation of organelle organization namespace: biological_process def: "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] synonym: "positive regulation of organelle organisation" EXACT [GOC:mah] synonym: "positive regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006996 ! organelle organization relationship: positively_regulates GO:0006996 ! organelle organization [Term] id: GO:0010639 name: negative regulation of organelle organization namespace: biological_process def: "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:dph, GOC:tb] synonym: "negative regulation of organelle organisation" EXACT [GOC:mah] synonym: "negative regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006996 ! organelle organization relationship: negatively_regulates GO:0006996 ! organelle organization [Term] id: GO:0010646 name: regulation of cell communication namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007154 ! cell communication relationship: regulates GO:0007154 ! cell communication [Term] id: GO:0010647 name: positive regulation of cell communication namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007154 ! cell communication relationship: positively_regulates GO:0007154 ! cell communication [Term] id: GO:0010648 name: negative regulation of cell communication namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:dph, GOC:tb] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007154 ! cell communication relationship: negatively_regulates GO:0007154 ! cell communication [Term] id: GO:0010656 name: negative regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "negative regulation of muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010657 ! muscle cell apoptotic process relationship: negatively_regulates GO:0010657 ! muscle cell apoptotic process [Term] id: GO:0010657 name: muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." [CL:0000187, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "muscle cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000187 ! muscle cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in CL:0000187 ! muscle cell relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0010658 name: striated muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "striated muscle cell apoptosis" NARROW [] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000737 ! striated muscle cell relationship: occurs_in CL:0000737 ! striated muscle cell [Term] id: GO:0010659 name: cardiac muscle cell apoptotic process namespace: biological_process def: "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [CL:0000746, GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010658 ! striated muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000746 ! cardiac muscle cell relationship: occurs_in CL:0000746 ! cardiac muscle cell [Term] id: GO:0010660 name: regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of muscle cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010657 ! muscle cell apoptotic process relationship: regulates GO:0010657 ! muscle cell apoptotic process [Term] id: GO:0010661 name: positive regulation of muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010657 ! muscle cell apoptotic process relationship: positively_regulates GO:0010657 ! muscle cell apoptotic process [Term] id: GO:0010662 name: regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010658 ! striated muscle cell apoptotic process relationship: regulates GO:0010658 ! striated muscle cell apoptotic process [Term] id: GO:0010663 name: positive regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010658 ! striated muscle cell apoptotic process relationship: positively_regulates GO:0010658 ! striated muscle cell apoptotic process [Term] id: GO:0010664 name: negative regulation of striated muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of striated muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of striated muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] synonym: "negative regulation of striated muscle cell apoptosis" NARROW [] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process relationship: negatively_regulates GO:0010658 ! striated muscle cell apoptotic process [Term] id: GO:0010665 name: regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010662 ! regulation of striated muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010659 ! cardiac muscle cell apoptotic process relationship: regulates GO:0010659 ! cardiac muscle cell apoptotic process [Term] id: GO:0010666 name: positive regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:dph, GOC:mtg_apoptosis, GOC:tb] synonym: "positive regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010663 ! positive regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process relationship: positively_regulates GO:0010659 ! cardiac muscle cell apoptotic process [Term] id: GO:0010667 name: negative regulation of cardiac muscle cell apoptotic process namespace: biological_process def: "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." [GOC:BHF, GOC:dph, GOC:mtg_apoptosis, GOC:rl, GOC:tb] synonym: "down regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "down-regulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "downregulation of cardiac muscle cell apoptosis" EXACT [GOC:dph, GOC:rl, GOC:tb] synonym: "inhibition of cardiac muscle cell apoptosis" NARROW [GOC:dph, GOC:rl, GOC:tb] synonym: "negative regulation of cardiac muscle cell apoptosis" NARROW [] is_a: GO:0010664 ! negative regulation of striated muscle cell apoptotic process is_a: GO:0010665 ! regulation of cardiac muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process relationship: negatively_regulates GO:0010659 ! cardiac muscle cell apoptotic process [Term] id: GO:0010668 name: ectodermal cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000221 ! ectodermal cell relationship: part_of GO:0007398 ! ectoderm development relationship: results_in_acquisition_of_features_of CL:0000221 ! ectodermal cell [Term] id: GO:0010700 name: negative regulation of norepinephrine secretion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033604 ! negative regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048243 ! norepinephrine secretion relationship: negatively_regulates GO:0048243 ! norepinephrine secretion [Term] id: GO:0010701 name: positive regulation of norepinephrine secretion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." [GOC:dph, GOC:tb] is_a: GO:0014061 ! regulation of norepinephrine secretion is_a: GO:0033605 ! positive regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048243 ! norepinephrine secretion relationship: positively_regulates GO:0048243 ! norepinephrine secretion [Term] id: GO:0010710 name: regulation of collagen catabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030574 ! collagen catabolic process relationship: regulates GO:0030574 ! collagen catabolic process [Term] id: GO:0010711 name: negative regulation of collagen catabolic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of collagen catabolic process" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010713 ! negative regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030574 ! collagen catabolic process relationship: negatively_regulates GO:0030574 ! collagen catabolic process [Term] id: GO:0010712 name: regulation of collagen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032963 ! collagen metabolic process relationship: regulates GO:0032963 ! collagen metabolic process [Term] id: GO:0010713 name: negative regulation of collagen metabolic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032963 ! collagen metabolic process relationship: negatively_regulates GO:0032963 ! collagen metabolic process [Term] id: GO:0010714 name: positive regulation of collagen metabolic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:dph, GOC:tb] synonym: "positive regulation of collagen metabolism" EXACT [GOC:dph, GOC:tb] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032963 ! collagen metabolic process relationship: positively_regulates GO:0032963 ! collagen metabolic process [Term] id: GO:0010715 name: regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022617 ! extracellular matrix disassembly relationship: regulates GO:0022617 ! extracellular matrix disassembly [Term] id: GO:0010716 name: negative regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:BHF, GOC:dph, GOC:tb] synonym: "down regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of extracellular matrix disassembly" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of extracellular matrix disassembly" NARROW [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix breakdown" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of extracellular matrix degradation" EXACT [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022617 ! extracellular matrix disassembly relationship: negatively_regulates GO:0022617 ! extracellular matrix disassembly [Term] id: GO:0010717 name: regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001837 ! epithelial to mesenchymal transition relationship: regulates GO:0001837 ! epithelial to mesenchymal transition [Term] id: GO:0010718 name: positive regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001837 ! epithelial to mesenchymal transition relationship: positively_regulates GO:0001837 ! epithelial to mesenchymal transition [Term] id: GO:0010719 name: negative regulation of epithelial to mesenchymal transition namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition relationship: negatively_regulates GO:0001837 ! epithelial to mesenchymal transition [Term] id: GO:0010720 name: positive regulation of cell development namespace: biological_process def: "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048468 ! cell development relationship: positively_regulates GO:0048468 ! cell development [Term] id: GO:0010721 name: negative regulation of cell development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048468 ! cell development relationship: negatively_regulates GO:0048468 ! cell development [Term] id: GO:0010761 name: fibroblast migration namespace: biological_process def: "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:BHF, GOC:dph, GOC:tb] synonym: "fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000057 ! fibroblast relationship: results_in_movement_of CL:0000057 ! fibroblast [Term] id: GO:0010762 name: regulation of fibroblast migration namespace: biological_process def: "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010761 ! fibroblast migration relationship: regulates GO:0010761 ! fibroblast migration [Term] id: GO:0010763 name: positive regulation of fibroblast migration namespace: biological_process def: "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010761 ! fibroblast migration relationship: positively_regulates GO:0010761 ! fibroblast migration [Term] id: GO:0010764 name: negative regulation of fibroblast migration namespace: biological_process def: "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." [GOC:dph, GOC:tb] synonym: "negative regulation of fibroblast cell migration" EXACT [GOC:dph] is_a: GO:0010762 ! regulation of fibroblast migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010761 ! fibroblast migration relationship: negatively_regulates GO:0010761 ! fibroblast migration [Term] id: GO:0010765 name: positive regulation of sodium ion transport namespace: biological_process def: "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006814 ! sodium ion transport relationship: positively_regulates GO:0006814 ! sodium ion transport [Term] id: GO:0010766 name: negative regulation of sodium ion transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006814 ! sodium ion transport relationship: negatively_regulates GO:0006814 ! sodium ion transport [Term] id: GO:0010769 name: regulation of cell morphogenesis involved in differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0022604 ! regulation of cell morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000904 ! cell morphogenesis involved in differentiation relationship: regulates GO:0000904 ! cell morphogenesis involved in differentiation [Term] id: GO:0010770 name: positive regulation of cell morphogenesis involved in differentiation namespace: biological_process def: "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000904 ! cell morphogenesis involved in differentiation relationship: positively_regulates GO:0000904 ! cell morphogenesis involved in differentiation [Term] id: GO:0010771 name: negative regulation of cell morphogenesis involved in differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0010769 ! regulation of cell morphogenesis involved in differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000904 ! cell morphogenesis involved in differentiation relationship: negatively_regulates GO:0000904 ! cell morphogenesis involved in differentiation [Term] id: GO:0010817 name: regulation of hormone levels namespace: biological_process def: "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." [GOC:BHF, GOC:dph, GOC:tb] [Term] id: GO:0010827 name: regulation of glucose transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] synonym: "regulation of glucose transport" RELATED [] is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904659 ! glucose transmembrane transport relationship: regulates GO:1904659 ! glucose transmembrane transport [Term] id: GO:0010828 name: positive regulation of glucose transmembrane transport namespace: biological_process def: "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of glucose transport" RELATED [] is_a: GO:0010827 ! regulation of glucose transmembrane transport is_a: GO:0034764 ! positive regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904659 ! glucose transmembrane transport relationship: positively_regulates GO:1904659 ! glucose transmembrane transport [Term] id: GO:0010829 name: negative regulation of glucose transmembrane transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:dph, GOC:tb] synonym: "negative regulation of glucose transport" RELATED [] is_a: GO:0010827 ! regulation of glucose transmembrane transport is_a: GO:0034763 ! negative regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904659 ! glucose transmembrane transport relationship: negatively_regulates GO:1904659 ! glucose transmembrane transport [Term] id: GO:0010830 name: regulation of myotube differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014902 ! myotube differentiation relationship: regulates GO:0014902 ! myotube differentiation [Term] id: GO:0010831 name: positive regulation of myotube differentiation namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014902 ! myotube differentiation relationship: positively_regulates GO:0014902 ! myotube differentiation [Term] id: GO:0010832 name: negative regulation of myotube differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:dph, GOC:tb] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014902 ! myotube differentiation relationship: negatively_regulates GO:0014902 ! myotube differentiation [Term] id: GO:0010842 name: retina layer formation namespace: biological_process def: "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." [GOC:ascb_2009, GOC:dph, GOC:tb, PMID:1270266] synonym: "retinal lamination" EXACT [GOC:dph, GOC:tb] synonym: "retinal layer formation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001781 ! layer of retina relationship: part_of GO:0003407 ! neural retina development relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye relationship: results_in_formation_of UBERON:0001781 ! layer of retina [Term] id: GO:0010876 name: lipid localization namespace: biological_process def: "Any process in which a lipid is transported to, or maintained in, a specific location." [GOC:BHF, GOC:dph, GOC:tb] synonym: "lipid localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid [Term] id: GO:0010893 name: positive regulation of steroid biosynthetic process namespace: biological_process def: "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:tb] is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0046889 ! positive regulation of lipid biosynthetic process is_a: GO:0050810 ! regulation of steroid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006694 ! steroid biosynthetic process relationship: positively_regulates GO:0006694 ! steroid biosynthetic process [Term] id: GO:0010894 name: negative regulation of steroid biosynthetic process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:BHF, GOC:tb] is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:0051055 ! negative regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006694 ! steroid biosynthetic process relationship: negatively_regulates GO:0006694 ! steroid biosynthetic process [Term] id: GO:0010906 name: regulation of glucose metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006006 ! glucose metabolic process relationship: regulates GO:0006006 ! glucose metabolic process [Term] id: GO:0010907 name: positive regulation of glucose metabolic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." [GOC:BHF, GOC:tb] synonym: "positive regulation of glucose metabolism" EXACT [GOC:tb] is_a: GO:0010906 ! regulation of glucose metabolic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006006 ! glucose metabolic process relationship: positively_regulates GO:0006006 ! glucose metabolic process [Term] id: GO:0010927 name: cellular component assembly involved in morphogenesis namespace: biological_process def: "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." [GOC:dph, GOC:tb] is_a: GO:0022607 ! cellular component assembly is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0022607 ! cellular component assembly intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0032989 ! cellular component morphogenesis [Term] id: GO:0010937 name: regulation of cytoplasmic microtubule depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." [GOC:dph, GOC:tb] is_a: GO:0031114 ! regulation of microtubule depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010938 ! cytoplasmic microtubule depolymerization relationship: regulates GO:0010938 ! cytoplasmic microtubule depolymerization [Term] id: GO:0010938 name: cytoplasmic microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." [GOC:dph, GOC:tb] is_a: GO:0007019 ! microtubule depolymerization is_a: GO:0031122 ! cytoplasmic microtubule organization intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: occurs_in GO:0005737 ! cytoplasm relationship: occurs_in GO:0005737 ! cytoplasm [Term] id: GO:0010948 name: negative regulation of cell cycle process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022402 ! cell cycle process relationship: negatively_regulates GO:0022402 ! cell cycle process created_by: tb creation_date: 2009-04-27T09:53:22Z [Term] id: GO:0010959 name: regulation of metal ion transport namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030001 ! metal ion transport relationship: regulates GO:0030001 ! metal ion transport created_by: tb creation_date: 2009-05-06T11:40:55Z [Term] id: GO:0010962 name: regulation of glucan biosynthetic process namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." [GOC:dph, GOC:tb] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009250 ! glucan biosynthetic process relationship: regulates GO:0009250 ! glucan biosynthetic process created_by: tb creation_date: 2009-05-11T12:17:53Z [Term] id: GO:0010966 name: regulation of phosphate transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006817 ! phosphate ion transport relationship: regulates GO:0006817 ! phosphate ion transport created_by: tb creation_date: 2009-05-20T11:42:50Z [Term] id: GO:0010968 name: regulation of microtubule nucleation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0031113 ! regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007020 ! microtubule nucleation relationship: regulates GO:0007020 ! microtubule nucleation created_by: tb creation_date: 2009-05-20T11:51:21Z [Term] id: GO:0010970 name: transport along microtubule namespace: biological_process def: "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." [GOC:dph, GOC:mah, GOC:tb] synonym: "establishment of localization by movement along microtubule" EXACT [GOC:dph] synonym: "microtubule-based transport" BROAD [] synonym: "movement along microtubule" EXACT [] is_a: GO:0007018 ! microtubule-based movement is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: results_in_transport_along GO:0005874 ! microtubule created_by: tb creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0010975 name: regulation of neuron projection development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "regulation of neurite development" NARROW [GOC:mah] synonym: "regulation of neurite formation" NARROW [GOC:mah] synonym: "regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031175 ! neuron projection development relationship: regulates GO:0031175 ! neuron projection development created_by: tb creation_date: 2009-06-01T10:44:45Z [Term] id: GO:0010976 name: positive regulation of neuron projection development namespace: biological_process def: "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "positive regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "positive regulation of neurite development" NARROW [GOC:mah] synonym: "positive regulation of neurite formation" NARROW [GOC:mah] synonym: "positive regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031346 ! positive regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0031175 ! neuron projection development relationship: positively_regulates GO:0031175 ! neuron projection development created_by: tb creation_date: 2009-06-01T10:46:44Z [Term] id: GO:0010977 name: negative regulation of neuron projection development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:dph, GOC:tb] synonym: "growth cone collapse" RELATED [GOC:pr] synonym: "negative regulation of neurite biosynthesis" NARROW [GOC:mah] synonym: "negative regulation of neurite development" NARROW [GOC:mah] synonym: "negative regulation of neurite formation" NARROW [GOC:mah] synonym: "negative regulation of neurite growth" NARROW [GOC:mah] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0031345 ! negative regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031175 ! neuron projection development relationship: negatively_regulates GO:0031175 ! neuron projection development created_by: tb creation_date: 2009-06-01T10:47:42Z [Term] id: GO:0012501 name: programmed cell death namespace: biological_process alt_id: GO:0016244 def: "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." [GOC:lr, GOC:mtg_apoptosis] comment: Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children. subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant subset: prokaryote_subset synonym: "caspase-independent apoptosis" RELATED [] synonym: "caspase-independent cell death" NARROW [] synonym: "non-apoptotic programmed cell death" NARROW [] synonym: "nonapoptotic programmed cell death" NARROW [] synonym: "PCD" RELATED [] synonym: "RCD" RELATED [] synonym: "regulated cell death" BROAD [] xref: Wikipedia:Programmed_cell_death is_a: GO:0008219 ! cell death intersection_of: GO:0008219 ! cell death intersection_of: starts_with GO:0007165 ! signal transduction relationship: starts_with GO:0007165 ! signal transduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24835" xsd:anyURI [Term] id: GO:0012505 name: endomembrane system namespace: cellular_component def: "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." [GOC:lh] subset: goslim_candida subset: goslim_flybase_ribbon subset: goslim_yeast xref: Wikipedia:Endomembrane_system is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005773 ! vacuole relationship: has_part GO:0005886 ! plasma membrane relationship: part_of CL:0000000 ! cell [Term] id: GO:0012506 name: vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." [GOC:mah, GOC:vesicle] xref: NIF_Subcellular:sao1153182838 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0031982 ! vesicle relationship: part_of GO:0031982 ! vesicle [Term] id: GO:0014003 name: oligodendrocyte development namespace: biological_process def: "The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system." [GOC:dgh, GOC:ef] synonym: "oligodendrocyte cell development" EXACT [] is_a: GO:0021782 ! glial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000128 ! oligodendrocyte relationship: part_of GO:0048709 ! oligodendrocyte differentiation relationship: results_in_development_of CL:0000128 ! oligodendrocyte [Term] id: GO:0014009 name: glial cell proliferation namespace: biological_process def: "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." [GOC:ef, ISBN:0878932585] synonym: "glia proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000125 ! glial cell relationship: acts_on_population_of CL:0000125 ! glial cell relationship: part_of GO:0042063 ! gliogenesis [Term] id: GO:0014010 name: Schwann cell proliferation namespace: biological_process def: "The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system." [GOC:ef, ISBN:0878932585] is_a: GO:0014009 ! glial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000218 ! myelinating Schwann cell relationship: acts_on_population_of CL:0000218 ! myelinating Schwann cell [Term] id: GO:0014013 name: regulation of gliogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] is_a: GO:0050767 ! regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042063 ! gliogenesis relationship: regulates GO:0042063 ! gliogenesis [Term] id: GO:0014014 name: negative regulation of gliogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "down regulation of gliogenesis" EXACT [] synonym: "down-regulation of gliogenesis" EXACT [] synonym: "downregulation of gliogenesis" EXACT [] synonym: "inhibition of gliogenesis" NARROW [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050768 ! negative regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042063 ! gliogenesis relationship: negatively_regulates GO:0042063 ! gliogenesis [Term] id: GO:0014015 name: positive regulation of gliogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." [GOC:ef] synonym: "activation of gliogenesis" NARROW [] synonym: "stimulation of gliogenesis" NARROW [] synonym: "up regulation of gliogenesis" EXACT [] synonym: "up-regulation of gliogenesis" EXACT [] synonym: "upregulation of gliogenesis" EXACT [] is_a: GO:0014013 ! regulation of gliogenesis is_a: GO:0050769 ! positive regulation of neurogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042063 ! gliogenesis relationship: positively_regulates GO:0042063 ! gliogenesis [Term] id: GO:0014016 name: neuroblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." [GOC:ef, ISBN:0878932585] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of GO:0048699 ! generation of neurons relationship: results_in_acquisition_of_features_of CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0014019 name: neuroblast development namespace: biological_process def: "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." [GOC:ef, ISBN:0878932585] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of GO:0014016 ! neuroblast differentiation relationship: results_in_development_of CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0014020 name: primary neural tube formation namespace: biological_process alt_id: GO:0014024 def: "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." [GOC:ef, ISBN:0878932585, PMID:15327780] synonym: "neural rod cavitation" RELATED [] synonym: "primary neural tube morphogenesis" EXACT [GOC:dph] synonym: "primary neurulation" EXACT [] is_a: GO:0001838 ! embryonic epithelial tube formation relationship: part_of GO:0001841 ! neural tube formation [Term] id: GO:0014023 name: neural rod formation namespace: biological_process def: "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005068 ! neural rod relationship: in_taxon NCBITaxon:32443 {all_only="true"} ! Teleostei relationship: only_in_taxon NCBITaxon:32443 ! Teleostei relationship: part_of GO:0014020 ! primary neural tube formation relationship: results_in_formation_of UBERON:0005068 ! neural rod [Term] id: GO:0014025 name: neural keel formation namespace: biological_process def: "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0007135 ! neural keel relationship: part_of GO:0014023 ! neural rod formation relationship: results_in_formation_of UBERON:0007135 ! neural keel [Term] id: GO:0014028 name: notochord formation namespace: biological_process def: "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." [GOC:dh, GOC:ef] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002328 ! notochord relationship: part_of GO:0007399 ! nervous system development relationship: part_of GO:0048570 ! notochord morphogenesis relationship: results_in_formation_of UBERON:0002328 ! notochord [Term] id: GO:0014029 name: neural crest formation namespace: biological_process def: "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:dh, GOC:ef] is_a: GO:0001837 ! epithelial to mesenchymal transition is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002342 ! neural crest relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_formation_of UBERON:0002342 ! neural crest [Term] id: GO:0014031 name: mesenchymal cell development namespace: biological_process def: "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0008019 ! mesenchymal cell relationship: part_of GO:0048762 ! mesenchymal cell differentiation relationship: results_in_development_of CL:0008019 ! mesenchymal cell [Term] id: GO:0014032 name: neural crest cell development namespace: biological_process def: "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dh, GOC:ef] is_a: GO:0048864 ! stem cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0011012 ! neural crest cell relationship: part_of GO:0014033 ! neural crest cell differentiation relationship: results_in_development_of CL:0011012 ! neural crest cell [Term] id: GO:0014033 name: neural crest cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." [GOC:dh, GOC:ef] is_a: GO:0048762 ! mesenchymal cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000333 ! migratory neural crest cell relationship: results_in_acquisition_of_features_of CL:0000333 ! migratory neural crest cell [Term] id: GO:0014037 name: Schwann cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." [GOC:ef] is_a: GO:0010001 ! glial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000218 ! myelinating Schwann cell relationship: part_of GO:0007422 ! peripheral nervous system development relationship: results_in_acquisition_of_features_of CL:0000218 ! myelinating Schwann cell [Term] id: GO:0014038 name: regulation of Schwann cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014037 ! Schwann cell differentiation relationship: regulates GO:0014037 ! Schwann cell differentiation [Term] id: GO:0014039 name: negative regulation of Schwann cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] synonym: "down regulation of Schwann cell differentiation" EXACT [] synonym: "down-regulation of Schwann cell differentiation" EXACT [] synonym: "downregulation of Schwann cell differentiation" EXACT [] synonym: "inhibition of Schwann cell differentiation" NARROW [] is_a: GO:0014038 ! regulation of Schwann cell differentiation is_a: GO:0045686 ! negative regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014037 ! Schwann cell differentiation relationship: negatively_regulates GO:0014037 ! Schwann cell differentiation [Term] id: GO:0014040 name: positive regulation of Schwann cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation." [GOC:ef] synonym: "activation of Schwann cell differentiation" NARROW [] synonym: "stimulation of Schwann cell differentiation" NARROW [] synonym: "up regulation of Schwann cell differentiation" EXACT [] synonym: "up-regulation of Schwann cell differentiation" EXACT [] synonym: "upregulation of Schwann cell differentiation" EXACT [] is_a: GO:0014038 ! regulation of Schwann cell differentiation is_a: GO:0045687 ! positive regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014037 ! Schwann cell differentiation relationship: positively_regulates GO:0014037 ! Schwann cell differentiation [Term] id: GO:0014041 name: regulation of neuron maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." [GOC:ef] is_a: GO:0045664 ! regulation of neuron differentiation is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042551 ! neuron maturation relationship: regulates GO:0042551 ! neuron maturation [Term] id: GO:0014042 name: positive regulation of neuron maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "activation of neuron maturation" NARROW [] synonym: "stimulation of neuron maturation" NARROW [] synonym: "up regulation of neuron maturation" EXACT [] synonym: "up-regulation of neuron maturation" EXACT [] synonym: "upregulation of neuron maturation" EXACT [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903431 ! positive regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042551 ! neuron maturation relationship: positively_regulates GO:0042551 ! neuron maturation [Term] id: GO:0014043 name: negative regulation of neuron maturation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." [GOC:ef] synonym: "down regulation of neuron maturation" EXACT [] synonym: "down-regulation of neuron maturation" EXACT [] synonym: "downregulation of neuron maturation" EXACT [] synonym: "inhibition of neuron maturation" NARROW [] is_a: GO:0014041 ! regulation of neuron maturation is_a: GO:1903430 ! negative regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042551 ! neuron maturation relationship: negatively_regulates GO:0042551 ! neuron maturation [Term] id: GO:0014044 name: Schwann cell development namespace: biological_process def: "The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function." [GOC:dgh, GOC:ef] is_a: GO:0021782 ! glial cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000218 ! myelinating Schwann cell relationship: part_of GO:0014037 ! Schwann cell differentiation relationship: results_in_development_of CL:0000218 ! myelinating Schwann cell [Term] id: GO:0014055 name: acetylcholine secretion, neurotransmission namespace: biological_process def: "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." [GOC:ef] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0061526 ! acetylcholine secretion intersection_of: GO:0061526 ! acetylcholine secretion intersection_of: part_of GO:0007271 ! synaptic transmission, cholinergic relationship: part_of GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0014056 name: regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014055 ! acetylcholine secretion, neurotransmission relationship: regulates GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: GO:0014057 name: positive regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "activation of acetylcholine secretion" NARROW [] synonym: "stimulation of acetylcholine secretion" NARROW [] synonym: "up regulation of acetylcholine secretion" EXACT [] synonym: "up-regulation of acetylcholine secretion" EXACT [] synonym: "upregulation of acetylcholine secretion" EXACT [] is_a: GO:0001956 ! positive regulation of neurotransmitter secretion is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032224 ! positive regulation of synaptic transmission, cholinergic is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission relationship: positively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: GO:0014058 name: negative regulation of acetylcholine secretion, neurotransmission namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." [GOC:ef] synonym: "down regulation of acetylcholine secretion" EXACT [] synonym: "down-regulation of acetylcholine secretion" EXACT [] synonym: "downregulation of acetylcholine secretion" EXACT [] synonym: "inhibition of acetylcholine secretion" NARROW [] is_a: GO:0014056 ! regulation of acetylcholine secretion, neurotransmission is_a: GO:0032223 ! negative regulation of synaptic transmission, cholinergic is_a: GO:0046929 ! negative regulation of neurotransmitter secretion is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission relationship: negatively_regulates GO:0014055 ! acetylcholine secretion, neurotransmission [Term] id: GO:0014061 name: regulation of norepinephrine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." [GOC:ef] synonym: "regulation of noradrenaline secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048243 ! norepinephrine secretion relationship: regulates GO:0048243 ! norepinephrine secretion [Term] id: GO:0014062 name: regulation of serotonin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "regulation of serotonin release" RELATED [GOC:tb] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001820 ! serotonin secretion relationship: regulates GO:0001820 ! serotonin secretion [Term] id: GO:0014063 name: negative regulation of serotonin secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "down regulation of serotonin secretion" EXACT [] synonym: "down-regulation of serotonin secretion" EXACT [] synonym: "downregulation of serotonin secretion" EXACT [] synonym: "inhibition of serotonin secretion" NARROW [] synonym: "positive regulation of serotonin release" RELATED [GOC:tb] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043271 ! negative regulation of monoatomic ion transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001820 ! serotonin secretion relationship: negatively_regulates GO:0001820 ! serotonin secretion [Term] id: GO:0014064 name: positive regulation of serotonin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." [GOC:ef] synonym: "activation of serotonin secretion" NARROW [] synonym: "positive regulation of serotonin release" RELATED [GOC:tb] synonym: "stimulation of serotonin secretion" NARROW [] synonym: "up regulation of serotonin secretion" EXACT [] synonym: "up-regulation of serotonin secretion" EXACT [] synonym: "upregulation of serotonin secretion" EXACT [] is_a: GO:0014062 ! regulation of serotonin secretion is_a: GO:0043270 ! positive regulation of monoatomic ion transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001820 ! serotonin secretion relationship: positively_regulates GO:0001820 ! serotonin secretion [Term] id: GO:0014070 name: response to organic cyclic compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." [GOC:ef] synonym: "response to organic cyclic substance" EXACT [GOC:mah] is_a: GO:0010033 ! response to organic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:33832 ! organic cyclic compound relationship: has_input CHEBI:33832 ! organic cyclic compound [Term] id: GO:0014075 name: response to amine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." [GOC:ef] synonym: "response to amine stimulus" EXACT [GOC:dos] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:32952 ! amine relationship: has_input CHEBI:32952 ! amine [Term] id: GO:0014706 name: striated muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." [CL:0000737, GOC:dph, GOC:mtg_muscle] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002036 ! striated muscle tissue relationship: results_in_development_of UBERON:0002036 ! striated muscle tissue [Term] id: GO:0014733 name: regulation of skeletal muscle adaptation namespace: biological_process def: "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "regulation of skeletal muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043501 ! skeletal muscle adaptation relationship: regulates GO:0043501 ! skeletal muscle adaptation [Term] id: GO:0014734 name: skeletal muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014897 ! striated muscle hypertrophy is_a: GO:0043501 ! skeletal muscle adaptation intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0014741 name: negative regulation of muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014896 ! muscle hypertrophy relationship: negatively_regulates GO:0014896 ! muscle hypertrophy [Term] id: GO:0014742 name: positive regulation of muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014896 ! muscle hypertrophy relationship: positively_regulates GO:0014896 ! muscle hypertrophy [Term] id: GO:0014743 name: regulation of muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle hypertrophy." [GOC:mtg_muscle] is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014896 ! muscle hypertrophy relationship: regulates GO:0014896 ! muscle hypertrophy [Term] id: GO:0014744 name: positive regulation of muscle adaptation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle adaptation." [GOC:mtg_muscle] synonym: "positive regulation of muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043500 ! muscle adaptation relationship: positively_regulates GO:0043500 ! muscle adaptation [Term] id: GO:0014745 name: negative regulation of muscle adaptation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." [GOC:mtg_muscle] synonym: "negative regulation of muscle plasticity" RELATED [] is_a: GO:0043502 ! regulation of muscle adaptation is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043500 ! muscle adaptation relationship: negatively_regulates GO:0043500 ! muscle adaptation [Term] id: GO:0014805 name: smooth muscle adaptation namespace: biological_process def: "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "smooth muscle plasticity" RELATED [] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue relationship: occurs_in UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0014807 name: regulation of somitogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somitogenesis." [GOC:mtg_muscle] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001756 ! somitogenesis relationship: regulates GO:0001756 ! somitogenesis [Term] id: GO:0014812 name: muscle cell migration namespace: biological_process def: "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000187, GOC:mtg_muscle] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000187 ! muscle cell relationship: results_in_movement_of CL:0000187 ! muscle cell [Term] id: GO:0014819 name: regulation of skeletal muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." [GOC:ef, GOC:mtg_muscle] is_a: GO:0006942 ! regulation of striated muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003009 ! skeletal muscle contraction relationship: regulates GO:0003009 ! skeletal muscle contraction [Term] id: GO:0014821 name: phasic smooth muscle contraction namespace: biological_process def: "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations." [GOC:mtg_muscle] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014827 name: intestine smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine." [GOC:mtg_muscle, MA:0001539, MSH:D007422] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014831 ! gastro-intestinal system smooth muscle contraction [Term] id: GO:0014831 name: gastro-intestinal system smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)." [GOC:mtg_muscle, MA:0001523, MSH:D041981] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014832 name: urinary bladder smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract." [GOC:mr, GOC:mtg_muscle, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0014848 ! urinary tract smooth muscle contraction property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0014848 name: urinary tract smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." [GOC:ef, GOC:mtg_muscle, MA:0000325, MSH:D014551] is_a: GO:0006939 ! smooth muscle contraction [Term] id: GO:0014849 name: ureter smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_muscle, MA:0000378] is_a: GO:0014821 ! phasic smooth muscle contraction is_a: GO:0014848 ! urinary tract smooth muscle contraction [Term] id: GO:0014852 name: regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014819 ! regulation of skeletal muscle contraction [Term] id: GO:0014855 name: striated muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:ef, GOC:mtg_muscle] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000737 ! striated muscle cell relationship: acts_on_population_of CL:0000737 ! striated muscle cell [Term] id: GO:0014856 name: skeletal muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000188 ! cell of skeletal muscle relationship: acts_on_population_of CL:0000188 ! cell of skeletal muscle [Term] id: GO:0014857 name: regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014856 ! skeletal muscle cell proliferation relationship: regulates GO:0014856 ! skeletal muscle cell proliferation [Term] id: GO:0014858 name: positive regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014856 ! skeletal muscle cell proliferation relationship: positively_regulates GO:0014856 ! skeletal muscle cell proliferation [Term] id: GO:0014859 name: negative regulation of skeletal muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." [CL:0000188, GOC:ef, GOC:mtg_muscle] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014857 ! regulation of skeletal muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation relationship: negatively_regulates GO:0014856 ! skeletal muscle cell proliferation [Term] id: GO:0014860 name: neurotransmitter secretion involved in regulation of skeletal muscle contraction namespace: biological_process def: "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." [GOC:dph, GOC:mtg_muscle, GOC:tb] synonym: "neurotransmitter secretion involved in control of skeletal muscle contraction" EXACT [GOC:dph, GOC:tb] is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: part_of GO:0014819 ! regulation of skeletal muscle contraction relationship: part_of GO:0014852 ! regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction [Term] id: GO:0014861 name: regulation of skeletal muscle contraction via regulation of action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:mtg_muscle] synonym: "regulation of skeletal muscle contraction via membrane action potential" RELATED [] is_a: GO:0014819 ! regulation of skeletal muscle contraction is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential relationship: regulates GO:0100001 ! regulation of skeletal muscle contraction by action potential [Term] id: GO:0014866 name: skeletal myofibril assembly namespace: biological_process def: "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." [GOC:ef, GOC:mtg_muscle] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0098723 ! skeletal muscle myofibril relationship: results_in_assembly_of GO:0098723 ! skeletal muscle myofibril [Term] id: GO:0014872 name: myoblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ef, GOC:mtg_muscle] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000056 ! myoblast relationship: has_input CL:0000056 ! myoblast [Term] id: GO:0014874 name: response to stimulus involved in regulation of muscle adaptation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] synonym: "response to stimulus involved in regulation of muscle plasticity" RELATED [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation relationship: part_of GO:0043502 ! regulation of muscle adaptation [Term] id: GO:0014878 name: response to electrical stimulus involved in regulation of muscle adaptation namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] synonym: "response to electrical stimulus involved in regulation of muscle plasticity" RELATED [] is_a: GO:0014874 ! response to stimulus involved in regulation of muscle adaptation is_a: GO:0051602 ! response to electrical stimulus intersection_of: GO:0051602 ! response to electrical stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation [Term] id: GO:0014879 name: detection of electrical stimulus involved in regulation of muscle adaptation namespace: biological_process def: "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation." [GOC:ef, GOC:mtg_muscle] is_a: GO:0014878 ! response to electrical stimulus involved in regulation of muscle adaptation is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0043502 ! regulation of muscle adaptation [Term] id: GO:0014887 name: cardiac muscle adaptation namespace: biological_process def: "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." [GOC:mtg_muscle] synonym: "cardiac muscle plasticity" RELATED [] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0001133 ! cardiac muscle tissue relationship: occurs_in UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0014888 name: striated muscle adaptation namespace: biological_process def: "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle] synonym: "striated muscle plasticity" RELATED [] is_a: GO:0043500 ! muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0002036 ! striated muscle tissue relationship: occurs_in UBERON:0002036 ! striated muscle tissue [Term] id: GO:0014895 name: smooth muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." [GOC:mtg_muscle] is_a: GO:0014805 ! smooth muscle adaptation is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: occurs_in UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0014896 name: muscle hypertrophy namespace: biological_process def: "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." [GOC:mtg_muscle] xref: Wikipedia:Muscle_hypertrophy is_a: GO:0003012 ! muscle system process relationship: occurs_in UBERON:0002385 ! muscle tissue [Term] id: GO:0014897 name: striated muscle hypertrophy namespace: biological_process def: "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." [GOC:mtg_muscle] is_a: GO:0014896 ! muscle hypertrophy intersection_of: GO:0014896 ! muscle hypertrophy intersection_of: has_input UBERON:0002036 ! striated muscle tissue relationship: has_input UBERON:0002036 ! striated muscle tissue [Term] id: GO:0014902 name: myotube differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002372 ! myotube relationship: results_in_acquisition_of_features_of CL:0002372 ! myotube [Term] id: GO:0014904 name: myotube cell development namespace: biological_process def: "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." [GOC:mtg_muscle] is_a: GO:0055002 ! striated muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0002372 ! myotube relationship: part_of GO:0014902 ! myotube differentiation relationship: results_in_development_of CL:0002372 ! myotube [Term] id: GO:0014909 name: smooth muscle cell migration namespace: biological_process def: "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000192 ! smooth muscle cell relationship: results_in_movement_of CL:0000192 ! smooth muscle cell [Term] id: GO:0014910 name: regulation of smooth muscle cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014909 ! smooth muscle cell migration relationship: regulates GO:0014909 ! smooth muscle cell migration [Term] id: GO:0014911 name: positive regulation of smooth muscle cell migration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030335 ! positive regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014909 ! smooth muscle cell migration relationship: positively_regulates GO:0014909 ! smooth muscle cell migration [Term] id: GO:0014912 name: negative regulation of smooth muscle cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." [CL:0000192, GOC:mtg_muscle] is_a: GO:0014910 ! regulation of smooth muscle cell migration is_a: GO:0030336 ! negative regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014909 ! smooth muscle cell migration relationship: negatively_regulates GO:0014909 ! smooth muscle cell migration [Term] id: GO:0015031 name: protein transport namespace: biological_process alt_id: GO:0015831 def: "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_chembl subset: goslim_pir subset: goslim_yeast synonym: "enzyme transport" NARROW [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein [Term] id: GO:0015075 name: monoatomic ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an ion from one side of a membrane to the other." [GOC:dgf, GOC:mtg_transport, ISBN:0815340729] synonym: "ion transmembrane transporter activity" BROAD [] synonym: "ion transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion relationship: has_primary_input CHEBI:24867 ! monoatomic ion relationship: part_of GO:0034220 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! monoatomic ion transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0015081 name: sodium ion transmembrane transporter activity namespace: molecular_function alt_id: GO:0022816 def: "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." [GOC:ai, GOC:BHF, RHEA:34963] synonym: "sodium transporter activity" EXACT [] xref: RHEA:34963 is_a: GO:0046873 ! metal ion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) relationship: has_primary_input CHEBI:29101 ! sodium(1+) relationship: part_of GO:0035725 ! sodium ion transmembrane transport property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24076" xsd:anyURI [Term] id: GO:0015101 name: organic cation transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-2161500 "abacavir [extracellular] => abacavir [cytosol]" xref: Reactome:R-HSA-549129 "OCT1 transports organic cations into hepatic cells" xref: Reactome:R-HSA-549279 "OCT2 mediates tubular uptake of organic cations in the kidney" xref: Reactome:R-HSA-549304 "OCT3 mediates renal clearance of organic cations" xref: Reactome:R-HSA-549322 "OCT1 transports organic cations out of hepatic cells" xref: Reactome:R-HSA-561054 "OCT2 mediates tubular secretion of organic cations in the kidney" xref: Reactome:R-HSA-561072 "OCT3 mediates renal uptake of organic cations" xref: Reactome:R-HSA-9794270 "SLCO1A2 transports Cipro(1+) into the cytosol" xref: Reactome:R-HSA-9794523 "SLC22A1 transports Cipro into renal cell" xref: Reactome:R-HSA-9795207 "SLC22A1 transports Cipro into hepatic cell" is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25697 ! organic cation relationship: has_primary_input CHEBI:25697 ! organic cation relationship: part_of GO:0015695 ! organic cation transport [Term] id: GO:0015103 name: inorganic anion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:ai] is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24834 ! inorganic anion relationship: has_primary_input CHEBI:24834 ! inorganic anion relationship: part_of GO:0015698 ! inorganic anion transport [Term] id: GO:0015106 name: bicarbonate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." [GOC:ai] xref: Reactome:R-HSA-2752067 "BESTs transport cytosolic HCO3- to extracellular region" xref: RHEA:28695 is_a: GO:0008514 ! organic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate relationship: part_of GO:0015701 ! bicarbonate transport [Term] id: GO:0015114 name: phosphate ion transmembrane transporter activity namespace: molecular_function alt_id: GO:1901677 def: "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." [GOC:ai] synonym: "phosphate transmembrane transporter activity" RELATED [GOC:vw] xref: RHEA:32823 is_a: GO:0015103 ! inorganic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:35780 ! phosphate ion relationship: has_primary_input CHEBI:35780 ! phosphate ion relationship: part_of GO:0035435 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! phosphate ion transmembrane transport created_by: pr creation_date: 2012-11-22T15:43:10Z [Term] id: GO:0015116 name: sulfate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." [GOC:ai] synonym: "sulfate permease activity" RELATED [] synonym: "sulphate transporter activity" EXACT [] xref: Reactome:R-HSA-3560789 "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol" xref: Reactome:R-HSA-427555 "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol" xref: Reactome:R-HSA-8875871 "SLC26A11 transports SO4(2-) from extracellular region to cytosol" xref: RHEA:34983 is_a: GO:0015103 ! inorganic anion transmembrane transporter activity is_a: GO:1901682 ! sulfur compound transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16189 ! sulfate relationship: has_primary_input CHEBI:16189 ! sulfate relationship: part_of GO:1902358 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! sulfate transmembrane transport [Term] id: GO:0015123 name: acetate transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:ai] is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:30089 ! acetate relationship: has_primary_input CHEBI:30089 ! acetate relationship: part_of GO:0035433 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! acetate transmembrane transport [Term] id: GO:0015125 name: bile acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." [GOC:ai] xref: Reactome:R-HSA-194079 "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194083 "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol" xref: Reactome:R-HSA-194130 "Transport (influx) of bile salts and acids by OATP-A" xref: Reactome:R-HSA-5661184 "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-5661198 "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)" xref: Reactome:R-HSA-9733964 "SLC51A:SLC51B transports bile salts from cytosol to extracellular region" is_a: GO:0005319 ! lipid transporter activity is_a: GO:0008028 ! monocarboxylic acid transmembrane transporter activity is_a: GO:1901618 ! organic hydroxy compound transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:3098 ! bile acid relationship: has_primary_input CHEBI:3098 ! bile acid relationship: part_of GO:0015721 ! bile acid and bile salt transport [Term] id: GO:0015127 name: bilirubin transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." [GOC:ai, ISBN:0198547684] xref: Reactome:R-HSA-5679031 "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-5679041 "ABCC2 transports BMG,BDG from cytosol to extracellular region" xref: Reactome:R-HSA-9661417 "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region" is_a: GO:0046943 ! carboxylic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-) relationship: has_primary_input CHEBI:57977 ! bilirubin(2-) relationship: part_of GO:0015723 ! bilirubin transport [Term] id: GO:0015144 name: carbohydrate transmembrane transporter activity namespace: molecular_function alt_id: GO:1901476 def: "Enables the transfer of carbohydrate from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] synonym: "carbohydrate transporter activity" RELATED [] synonym: "sugar transporter" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16646 ! carbohydrate relationship: has_primary_input CHEBI:16646 ! carbohydrate relationship: part_of GO:0034219 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate transmembrane transport [Term] id: GO:0015145 name: monosaccharide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a monosaccharide from one side of a membrane to the other." [GOC:jl, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0051119 ! sugar transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:35381 ! monosaccharide relationship: has_primary_input CHEBI:35381 ! monosaccharide relationship: part_of GO:0015749 ! monosaccharide transmembrane transport [Term] id: GO:0015149 name: hexose transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] xref: Reactome:R-HSA-189242 "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region" xref: Reactome:R-HSA-5638222 "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region" is_a: GO:0015145 ! monosaccharide transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:18133 ! hexose relationship: has_primary_input CHEBI:18133 ! hexose relationship: part_of GO:0008645 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! hexose transmembrane transport [Term] id: GO:0015159 name: polysaccharide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] is_a: GO:0015144 ! carbohydrate transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide relationship: part_of GO:0015774 ! polysaccharide transport [Term] id: GO:0015171 name: amino acid transmembrane transporter activity namespace: molecular_function alt_id: GO:0015359 def: "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "amino acid permease activity" EXACT [] synonym: "amino acid transporter activity" BROAD [] synonym: "amino acid/choline transmembrane transporter activity" NARROW [] synonym: "general amino acid permease activity" RELATED [] synonym: "hydroxy/aromatic amino acid permease activity" RELATED [] xref: Reactome:R-HSA-210439 "glutamate uptake by astrocytes" xref: Reactome:R-HSA-212642 "L-Glutamine transport into neurons" xref: Reactome:R-HSA-351963 "SLC6A18 transports Gly from extracellular region to cytosol" xref: Reactome:R-HSA-351987 "SLC6A6-mediated uptake of taurine and beta-alanine" xref: Reactome:R-HSA-352029 "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine" xref: Reactome:R-HSA-352052 "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol" xref: Reactome:R-HSA-352059 "SLC6A15-mediated amino acid uptake" xref: Reactome:R-HSA-352103 "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352107 "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids" xref: Reactome:R-HSA-352108 "SLC38A2 (ATA2)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352119 "SLC38A1 (ATA1)-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352136 "SLC38A4 (ATA3)-mediated uptake of arginine and lysine" xref: Reactome:R-HSA-352158 "SLC16A10-mediated uptake of aromatic amino acids" xref: Reactome:R-HSA-352174 "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine" xref: Reactome:R-HSA-352182 "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine" xref: Reactome:R-HSA-352191 "SLC7A8-mediated uptake of neutral amino acids" xref: Reactome:R-HSA-352232 "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol" xref: Reactome:R-HSA-352347 "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine" xref: Reactome:R-HSA-352354 "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine" xref: Reactome:R-HSA-352364 "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine" xref: Reactome:R-HSA-352371 "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine" xref: Reactome:R-HSA-352379 "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane" xref: Reactome:R-HSA-352385 "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane" xref: Reactome:R-HSA-375405 "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-375417 "SLC36A1-mediated uptake of glycine, proline, and alanine" xref: Reactome:R-HSA-375473 "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375487 "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-375768 "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375770 "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375776 "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-375790 "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids" xref: Reactome:R-HSA-376200 "SLC7A10-mediated uptake of small neutral amino acids" xref: Reactome:R-HSA-378513 "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate" xref: Reactome:R-HSA-379415 "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-379426 "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine" xref: Reactome:R-HSA-379432 "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5653850 "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol" xref: Reactome:R-HSA-5655702 "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5659674 "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5659734 "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol" xref: Reactome:R-HSA-5659755 "Defective SLC6A18 does not transport Gly from extracellular region to cytosol" xref: Reactome:R-HSA-5660694 "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol" xref: Reactome:R-HSA-5660890 "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu" xref: Reactome:R-HSA-5660910 "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane" xref: Reactome:R-HSA-888592 "Loading of GABA into clathrin sculpted GABA transport vesicle lumen" xref: Reactome:R-HSA-8952726 "SLC38A9 transports L-Arg from lysosomal lumen to cytosol" is_a: GO:0005342 ! organic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33709 ! amino acid relationship: has_primary_input CHEBI:33709 ! amino acid relationship: part_of GO:0003333 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! amino acid transmembrane transport [Term] id: GO:0015205 name: nucleobase transmembrane transporter activity namespace: molecular_function alt_id: GO:0015392 def: "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." [ISBN:0198506732] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:18282 ! nucleobase relationship: has_primary_input CHEBI:18282 ! nucleobase relationship: part_of GO:0015851 ! nucleobase transport [Term] id: GO:0015318 name: inorganic molecular entity transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." [GOC:mtg_transport, ISBN:0815340729] subset: gocheck_do_not_annotate synonym: "inorganic solute uptake transmembrane transporter activity" EXACT [] synonym: "inorganic uptake permease activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24835 ! inorganic molecular entity relationship: has_primary_input CHEBI:24835 ! inorganic molecular entity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14372" xsd:anyURI [Term] id: GO:0015629 name: actin cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." [GOC:jl, ISBN:0395825172, ISBN:0815316194] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015630 name: microtubule cytoskeleton namespace: cellular_component def: "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." [GOC:jl, ISBN:0395825172] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0015669 name: gas transport namespace: biological_process def: "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport [Term] id: GO:0015671 name: oxygen transport namespace: biological_process def: "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0015669 ! gas transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:15379 ! dioxygen relationship: has_primary_input CHEBI:15379 ! dioxygen [Term] id: GO:0015695 name: organic cation transport namespace: biological_process def: "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." [GOC:ai] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:25697 ! organic cation relationship: has_primary_input CHEBI:25697 ! organic cation [Term] id: GO:0015698 name: inorganic anion transport namespace: biological_process def: "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." [GOC:krc] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24834 ! inorganic anion relationship: has_primary_input CHEBI:24834 ! inorganic anion [Term] id: GO:0015701 name: bicarbonate transport namespace: biological_process def: "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0015711 ! organic anion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:17544 ! hydrogencarbonate relationship: has_primary_input CHEBI:17544 ! hydrogencarbonate [Term] id: GO:0015711 name: organic anion transport namespace: biological_process def: "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." [GOC:ai, GOC:krc] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:25696 ! organic anion relationship: has_primary_input CHEBI:25696 ! organic anion [Term] id: GO:0015718 name: monocarboxylic acid transport namespace: biological_process def: "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0046942 ! carboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion [Term] id: GO:0015721 name: bile acid and bile salt transport namespace: biological_process def: "The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:krc, PMID:12663868, PMID:14699511] synonym: "bile acid transport" NARROW [] synonym: "bile salt transport" NARROW [] is_a: GO:0006869 ! lipid transport is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0015849 ! organic acid transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:3098 ! bile acid relationship: has_primary_input CHEBI:3098 ! bile acid [Term] id: GO:0015723 name: bilirubin transport namespace: biological_process def: "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:krc] is_a: GO:0006835 ! dicarboxylic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:57977 ! bilirubin(2-) relationship: has_primary_input CHEBI:57977 ! bilirubin(2-) [Term] id: GO:0015749 name: monosaccharide transmembrane transport namespace: biological_process alt_id: GO:1905950 def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." [GO_REF:0000069, GOC:TermGenie, GOC:vw] synonym: "monosaccharide transport" RELATED [] is_a: GO:0034219 ! carbohydrate transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35381 ! monosaccharide intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:35381 ! monosaccharide created_by: vw creation_date: 2017-02-19T10:41:27Z [Term] id: GO:0015774 name: polysaccharide transport namespace: biological_process def: "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." [GOC:ai] is_a: GO:0008643 ! carbohydrate transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide relationship: part_of GO:0033037 ! polysaccharide localization [Term] id: GO:0015833 name: peptide transport namespace: biological_process def: "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir is_a: GO:0042886 ! amide transport is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16670 ! peptide relationship: has_primary_input CHEBI:16670 ! peptide [Term] id: GO:0015837 name: amine transport namespace: biological_process def: "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] subset: goslim_pir synonym: "amine/polyamine transport" RELATED [] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:32952 ! amine relationship: has_primary_input CHEBI:32952 ! amine [Term] id: GO:0015844 name: monoamine transport namespace: biological_process alt_id: GO:0015873 def: "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:63534 ! monoamine relationship: has_primary_input CHEBI:63534 ! monoamine [Term] id: GO:0015849 name: organic acid transport namespace: biological_process def: "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] subset: goslim_pir is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:64709 ! organic acid relationship: has_primary_input CHEBI:64709 ! organic acid [Term] id: GO:0015850 name: organic hydroxy compound transport namespace: biological_process def: "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." [GOC:ai] synonym: "organic alcohol transport" EXACT [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound [Term] id: GO:0015851 name: nucleobase transport namespace: biological_process def: "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [ISBN:0198506732] synonym: "nucleobase transmembrane transport" EXACT [GOC:mah] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18282 ! nucleobase relationship: has_primary_input CHEBI:18282 ! nucleobase [Term] id: GO:0015869 name: protein-DNA complex transport namespace: biological_process def: "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "DNA-protein complex transport" EXACT [GOC:mah] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0015931 ! nucleobase-containing compound transport is_a: GO:0031503 ! protein-containing complex localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0032993 ! protein-DNA complex relationship: has_primary_input GO:0032993 ! protein-DNA complex [Term] id: GO:0015870 name: acetylcholine transport namespace: biological_process def: "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." [GOC:ai] is_a: GO:0015695 ! organic cation transport is_a: GO:0071705 ! nitrogen compound transport is_a: GO:1901374 ! acetate ester transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:15355 ! acetylcholine relationship: has_primary_input CHEBI:15355 ! acetylcholine [Term] id: GO:0015874 name: norepinephrine transport namespace: biological_process def: "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai, ISBN:0198506732] synonym: "levarterenol transport" EXACT [] synonym: "noradrenaline transport" EXACT [] is_a: GO:0015695 ! organic cation transport is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0015931 name: nucleobase-containing compound transport namespace: biological_process def: "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_pir subset: goslim_yeast synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0071702 ! organic substance transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0015932 name: nucleobase-containing compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." [GOC:ai] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity" RELATED [GOC:dph, GOC:tb] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: part_of GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0015980 name: energy derivation by oxidation of organic compounds namespace: biological_process def: "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released." [GOC:mah] synonym: "chemoorganotrophy" EXACT [] is_a: GO:0006091 ! generation of precursor metabolites and energy [Term] id: GO:0016020 name: membrane namespace: cellular_component alt_id: GO:0016021 alt_id: GO:0098589 alt_id: GO:0098805 def: "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." [GOC:dos, GOC:mah, ISBN:0815316194] subset: goslim_candida subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics subset: goslim_pir subset: goslim_plant subset: goslim_yeast synonym: "integral component of membrane" NARROW [] synonym: "integral to membrane" NARROW [] synonym: "membrane region" NARROW [] synonym: "region of membrane" NARROW [] synonym: "transmembrane" RELATED [GOC:mah] synonym: "whole membrane" NARROW [] xref: Wikipedia:Biological_membrane xref: Wikipedia:Transmembrane_protein is_a: GO:0110165 ! cellular anatomical entity disjoint_from: GO:0031012 ! extracellular matrix creation_date: 2014-03-06T11:37:54Z [Term] id: GO:0016042 name: lipid catabolic process namespace: biological_process alt_id: GO:0006724 alt_id: GO:0044240 def: "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." [GOC:go_curators] synonym: "lipid breakdown" EXACT [] synonym: "lipid catabolism" EXACT [] synonym: "lipid degradation" EXACT [] synonym: "lipolysis" EXACT [] synonym: "multicellular organism lipid catabolic process" NARROW [] synonym: "multicellular organismal lipid catabolic process" NARROW [] xref: Wikipedia:Lipid_catabolism is_a: GO:0006629 ! lipid metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18059 ! lipid relationship: has_primary_input CHEBI:18059 ! lipid [Term] id: GO:0016043 name: cellular component organization namespace: biological_process alt_id: GO:0044235 alt_id: GO:0071842 def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:ai, GOC:jl, GOC:mah] subset: goslim_agr subset: goslim_mouse subset: goslim_pir subset: goslim_plant synonym: "cell organisation" EXACT [] synonym: "cell organization and biogenesis" RELATED [GOC:mah] synonym: "cellular component organisation at cellular level" EXACT [GOC:mah] synonym: "cellular component organisation in other organism" EXACT [GOC:mah] synonym: "cellular component organization at cellular level" EXACT [] synonym: "cellular component organization in other organism" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0005575 ! cellular_component relationship: results_in_organization_of GO:0005575 ! cellular_component [Term] id: GO:0016049 name: cell growth namespace: biological_process alt_id: GO:0048591 def: "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." [GOC:ai] subset: gocheck_do_not_annotate subset: goslim_drosophila subset: goslim_pir subset: goslim_plant synonym: "cell expansion" RELATED [] synonym: "cellular growth" EXACT [] synonym: "growth of cell" EXACT [] synonym: "metabolic process resulting in cell growth" RELATED [] synonym: "metabolism resulting in cell growth" RELATED [] synonym: "non-developmental cell growth" RELATED [GOC:mah] synonym: "non-developmental growth of a unicellular organism" RELATED [GOC:mah] is_a: GO:0009987 ! cellular process is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000000 ! cell relationship: results_in_growth_of CL:0000000 ! cell [Term] id: GO:0016050 name: vesicle organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." [GOC:mah] subset: goslim_pir subset: goslim_yeast synonym: "vesicle organisation" EXACT [] synonym: "vesicle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031982 ! vesicle relationship: results_in_organization_of GO:0031982 ! vesicle [Term] id: GO:0016051 name: carbohydrate biosynthetic process namespace: biological_process alt_id: GO:0006093 def: "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "anabolic carbohydrate metabolic process" EXACT [] synonym: "anabolic carbohydrate metabolism" EXACT [] synonym: "carbohydrate anabolism" EXACT [] synonym: "carbohydrate biosynthesis" EXACT [] synonym: "carbohydrate formation" EXACT [] synonym: "carbohydrate synthesis" EXACT [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16646 ! carbohydrate relationship: has_primary_output CHEBI:16646 ! carbohydrate [Term] id: GO:0016052 name: carbohydrate catabolic process namespace: biological_process alt_id: GO:0006095 alt_id: GO:0044276 alt_id: GO:0044724 def: "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." [ISBN:0198506732] synonym: "carbohydrate breakdown" EXACT [] synonym: "carbohydrate catabolism" EXACT [] synonym: "carbohydrate degradation" EXACT [] synonym: "catabolic carbohydrate metabolic process" EXACT [] synonym: "catabolic carbohydrate metabolism" EXACT [] synonym: "multicellular organismal carbohydrate catabolic process" NARROW [] synonym: "single-organism carbohydrate catabolic process" RELATED [] is_a: GO:0005975 ! carbohydrate metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16646 ! carbohydrate relationship: has_primary_input CHEBI:16646 ! carbohydrate created_by: jl creation_date: 2012-10-23T16:34:39Z [Term] id: GO:0016053 name: organic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid anabolism" EXACT [] synonym: "organic acid biosynthesis" EXACT [] synonym: "organic acid formation" EXACT [] synonym: "organic acid synthesis" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:64709 ! organic acid relationship: has_primary_output CHEBI:64709 ! organic acid [Term] id: GO:0016054 name: organic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." [ISBN:0198506732] synonym: "organic acid breakdown" EXACT [] synonym: "organic acid catabolism" EXACT [] synonym: "organic acid degradation" EXACT [] is_a: GO:0006082 ! organic acid metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:64709 ! organic acid relationship: has_primary_input CHEBI:64709 ! organic acid [Term] id: GO:0016057 name: regulation of membrane potential in photoreceptor cell namespace: biological_process def: "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." [GOC:dph, GOC:hb, GOC:tb] synonym: "changes in polarization state of photoreceptor cell membrane" EXACT [GOC:dph, GOC:tb] is_a: GO:0042391 ! regulation of membrane potential intersection_of: GO:0042391 ! regulation of membrane potential intersection_of: occurs_in CL:0000210 ! photoreceptor cell relationship: occurs_in CL:0000210 ! photoreceptor cell [Term] id: GO:0016070 name: RNA metabolic process namespace: biological_process def: "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." [ISBN:0198506732] subset: goslim_agr subset: goslim_candida subset: goslim_metagenomics subset: goslim_pir subset: prokaryote_subset synonym: "RNA metabolism" EXACT [] is_a: GO:0090304 ! nucleic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid relationship: has_primary_input_or_output CHEBI:33697 ! ribonucleic acid [Term] id: GO:0016192 name: vesicle-mediated transport namespace: biological_process alt_id: GO:0006899 def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe synonym: "nonselective vesicle transport" NARROW [] synonym: "protein sorting along secretory pathway" RELATED [] synonym: "vesicle trafficking" RELATED [] synonym: "vesicle transport" EXACT [] synonym: "vesicular transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: process_has_causal_agent GO:0031982 ! vesicle relationship: process_has_causal_agent GO:0031982 ! vesicle [Term] id: GO:0016202 name: regulation of striated muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle development." [GOC:go_curators] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014706 ! striated muscle tissue development relationship: regulates GO:0014706 ! striated muscle tissue development [Term] id: GO:0016301 name: kinase activity namespace: molecular_function def: "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [ISBN:0198506732] comment: Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. subset: goslim_chembl subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant subset: goslim_yeast synonym: "phosphokinase activity" EXACT [] xref: Reactome:R-HSA-6788855 "FN3KRP phosphorylates PsiAm, RibAm" xref: Reactome:R-HSA-6788867 "FN3K phosphorylates ketosamines" is_a: GO:0016772 ! transferase activity, transferring phosphorus-containing groups property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0016310 name: phosphorylation namespace: biological_process def: "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." [ISBN:0198506732] subset: goslim_chembl subset: goslim_metagenomics xref: Wikipedia:Phosphorylation is_a: GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0016321 name: female meiosis chromosome segregation namespace: biological_process def: "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." [GOC:ai] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0045132 ! meiotic chromosome segregation intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0007143 ! female meiotic nuclear division relationship: part_of GO:0007143 ! female meiotic nuclear division [Term] id: GO:0016325 name: oocyte microtubule cytoskeleton organization namespace: biological_process alt_id: GO:0048130 def: "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." [GOC:mtg_sensu, PMID:11231123] synonym: "oocyte microtubule cytoskeleton organisation" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030951 ! establishment or maintenance of microtubule cytoskeleton polarity intersection_of: GO:0016043 ! cellular component organization intersection_of: occurs_in CL:0000023 ! oocyte intersection_of: results_in_organization_of GO:0015630 ! microtubule cytoskeleton relationship: occurs_in CL:0000023 ! oocyte relationship: part_of GO:0007308 ! oocyte construction [Term] id: GO:0016331 name: morphogenesis of embryonic epithelium namespace: biological_process def: "The process in which the anatomical structures of embryonic epithelia are generated and organized." [GOC:jl] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0048598 ! embryonic morphogenesis [Term] id: GO:0016477 name: cell migration namespace: biological_process def: "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." [GOC:cjm, GOC:dph, GOC:ems, GOC:pf, Wikipedia:Cell_migration] xref: Wikipedia:Cell_migration is_a: GO:0048870 ! cell motility property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24787" xsd:anyURI [Term] id: GO:0016525 name: negative regulation of angiogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." [GOC:go_curators] synonym: "down regulation of angiogenesis" EXACT [] synonym: "down-regulation of angiogenesis" EXACT [] synonym: "downregulation of angiogenesis" EXACT [] synonym: "inhibition of angiogenesis" NARROW [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001525 ! angiogenesis relationship: negatively_regulates GO:0001525 ! angiogenesis [Term] id: GO:0016528 name: sarcoplasm namespace: cellular_component def: "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." [ISBN:0198547684] xref: Wikipedia:Sarcoplasm is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of CL:0000187 ! muscle cell relationship: part_of CL:0000187 ! muscle cell property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0016740 name: transferase activity namespace: molecular_function def: "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: prokaryote_subset xref: EC:2.-.-.- xref: Reactome:R-HSA-1483089 "PE is converted to PS by PTDSS2" xref: Reactome:R-HSA-1483186 "PC is converted to PS by PTDSS1" xref: Reactome:R-HSA-5668414 "TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK" xref: Reactome:R-HSA-8868783 "TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248" is_a: GO:0003824 ! catalytic activity property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0016772 name: transferase activity, transferring phosphorus-containing groups namespace: molecular_function def: "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:jl, ISBN:0198506732] comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides. subset: goslim_chembl xref: EC:2.7.-.- is_a: GO:0016740 ! transferase activity property_value: isDefinedBy http://purl.obolibrary.org/obo/go.owl [Term] id: GO:0016787 name: hydrolase activity namespace: molecular_function def: "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." [ISBN:0198506732] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_mouse subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: prokaryote_subset xref: EC:3.-.-.- xref: Reactome:R-HSA-1236938 "Partial proteolysis of antigen in phagolysosomes" xref: Reactome:R-HSA-2029475 "Production of AA by iPLA2 upon FCGR activation" xref: Reactome:R-HSA-5694583 "ABHD4 hydrolyses NAPE" xref: Reactome:R-HSA-5695964 "ABHD14B hydrolyses PNPB" xref: Reactome:R-HSA-6786190 "CMBL hydrolyses OM to OLMS" xref: Reactome:R-HSA-6788295 "HDHD1:Mg2+ dephosphorylates PURIDP" xref: Reactome:R-HSA-8938314 "ENPPs hydrolyse CoA-SH to PPANT, PAP" xref: Reactome:R-HSA-8952137 "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate" is_a: GO:0003824 ! catalytic activity [Term] id: GO:0016788 name: hydrolase activity, acting on ester bonds namespace: molecular_function def: "Catalysis of the hydrolysis of any ester bond." [GOC:jl] subset: goslim_chembl synonym: "esterase activity" EXACT [] xref: EC:3.1.-.- xref: Reactome:R-HSA-162729 "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid" xref: Reactome:R-HSA-9023617 "Butyrylcholinesterase hydrolyzes acyl Ghrelin" xref: Reactome:R-HSA-9023619 "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin" xref: Reactome:R-HSA-9749609 "BCHE hydrolyzes ASA-" is_a: GO:0016787 ! hydrolase activity [Term] id: GO:0017085 name: response to insecticide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." [GOC:curators] synonym: "insecticide resistance" RELATED [] synonym: "insecticide susceptibility/resistance" RELATED [] is_a: GO:0009636 ! response to toxic substance [Term] id: GO:0017126 name: nucleologenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." [GOC:jl, ISBN:0198506732] synonym: "nucleolus assembly" NARROW [GOC:mah] synonym: "nucleolus biogenesis" EXACT [] is_a: GO:0007000 ! nucleolus organization is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: has_output GO:0005730 ! nucleolus relationship: has_output GO:0005730 ! nucleolus [Term] id: GO:0017145 name: stem cell division namespace: biological_process def: "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." [GOC:jid, ISBN:0582227089] synonym: "stem cell renewal" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000034 ! stem cell relationship: has_input CL:0000034 ! stem cell property_value: RO:0002161 NCBITaxon_Union:0000023 [Term] id: GO:0017148 name: negative regulation of translation namespace: biological_process alt_id: GO:0016478 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:isa_complete] synonym: "down regulation of protein biosynthetic process" EXACT [] synonym: "down-regulation of protein biosynthetic process" EXACT [] synonym: "downregulation of protein biosynthetic process" EXACT [] synonym: "inhibition of protein biosynthetic process" NARROW [] synonym: "negative regulation of protein anabolism" EXACT [] synonym: "negative regulation of protein biosynthesis" EXACT [] synonym: "negative regulation of protein biosynthetic process" EXACT [] synonym: "negative regulation of protein formation" EXACT [] synonym: "negative regulation of protein synthesis" EXACT [] synonym: "protein biosynthesis inhibitor activity" RELATED [] synonym: "protein biosynthetic process inhibitor activity" RELATED [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0010629 ! negative regulation of gene expression is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006412 ! translation relationship: negatively_regulates GO:0006412 ! translation [Term] id: GO:0017157 name: regulation of exocytosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of exocytosis." [GOC:go_curators] is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006887 ! exocytosis relationship: regulates GO:0006887 ! exocytosis [Term] id: GO:0018130 name: heterocycle biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198547684] synonym: "heterocycle anabolism" EXACT [] synonym: "heterocycle biosynthesis" EXACT [] synonym: "heterocycle formation" EXACT [] synonym: "heterocycle synthesis" EXACT [] is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:5686 ! heterocyclic compound relationship: has_primary_output CHEBI:5686 ! heterocyclic compound [Term] id: GO:0018958 name: phenol-containing compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] comment: Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds. synonym: "carbolic acid metabolic process" EXACT [] synonym: "carbolic acid metabolism" EXACT [] synonym: "hydroxybenzene metabolic process" EXACT [] synonym: "hydroxybenzene metabolism" EXACT [] synonym: "phenol-containing compound metabolism" EXACT [] xref: UM-BBD_pathwayID:phe is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33853 ! phenols relationship: has_primary_input_or_output CHEBI:33853 ! phenols [Term] id: GO:0019098 name: reproductive behavior namespace: biological_process alt_id: GO:0033057 alt_id: GO:0044704 alt_id: GO:0044705 def: "The specific behavior of an organism that is associated with reproduction." [GOC:jl, GOC:pr] synonym: "multi-organism reproductive behavior" NARROW [] synonym: "multicellular organism reproductive behavior" NARROW [] synonym: "reproductive behavior in a multicellular organism" EXACT [] synonym: "reproductive behaviour" EXACT [] synonym: "single-organism reproductive behavior" RELATED [] is_a: GO:0007610 ! behavior is_a: GO:0022414 ! reproductive process intersection_of: GO:0007610 ! behavior intersection_of: part_of GO:0032504 ! multicellular organism reproduction relationship: part_of GO:0032504 ! multicellular organism reproduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23491" xsd:anyURI created_by: jl creation_date: 2012-09-19T16:01:37Z [Term] id: GO:0019216 name: regulation of lipid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "regulation of lipid metabolism" EXACT [] is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006629 ! lipid metabolic process relationship: regulates GO:0006629 ! lipid metabolic process [Term] id: GO:0019218 name: regulation of steroid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "regulation of steroid metabolism" EXACT [] is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008202 ! steroid metabolic process relationship: regulates GO:0008202 ! steroid metabolic process [Term] id: GO:0019219 name: regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006139 ! nucleobase-containing compound metabolic process relationship: regulates GO:0006139 ! nucleobase-containing compound metabolic process [Term] id: GO:0019220 name: regulation of phosphate metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "regulation of phosphate metabolism" EXACT [] is_a: GO:0051174 ! regulation of phosphorus metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006796 ! phosphate-containing compound metabolic process relationship: regulates GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0019222 name: regulation of metabolic process namespace: biological_process alt_id: GO:0044246 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." [GOC:go_curators] subset: goslim_metagenomics synonym: "regulation of metabolism" EXACT [] synonym: "regulation of multicellular organismal metabolic process" NARROW [] synonym: "regulation of organismal metabolic process" NARROW [GOC:tb] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008152 ! metabolic process relationship: regulates GO:0008152 ! metabolic process [Term] id: GO:0019226 name: transmission of nerve impulse namespace: biological_process def: "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." [GOC:curators, ISBN:0815316194] synonym: "conduction of nerve impulse" EXACT [GOC:dph] synonym: "signal transmission along a neuron" EXACT [] is_a: GO:0050877 ! nervous system process relationship: has_part GO:0001508 ! action potential relationship: has_part GO:0007268 ! chemical synaptic transmission relationship: part_of GO:0007154 ! cell communication [Term] id: GO:0019228 name: neuronal action potential namespace: biological_process def: "An action potential that occurs in a neuron." [GOC:dph, GOC:isa_complete, GOC:tb] synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:0000540 ! neuron relationship: occurs_in CL:0000540 ! neuron relationship: part_of GO:0019226 ! transmission of nerve impulse [Term] id: GO:0019233 name: sensory perception of pain namespace: biological_process def: "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process." [GOC:curators] synonym: "nociception" RELATED [] synonym: "perception of physiological pain" NARROW [] xref: Wikipedia:Nociception is_a: GO:0007600 ! sensory perception [Term] id: GO:0019318 name: hexose metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose metabolism" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18133 ! hexose relationship: has_primary_input_or_output CHEBI:18133 ! hexose [Term] id: GO:0019319 name: hexose biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose anabolism" EXACT [] synonym: "hexose biosynthesis" EXACT [] synonym: "hexose formation" EXACT [] synonym: "hexose synthesis" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046364 ! monosaccharide biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18133 ! hexose relationship: has_primary_output CHEBI:18133 ! hexose [Term] id: GO:0019320 name: hexose catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." [ISBN:0198506732] synonym: "hexose breakdown" EXACT [] synonym: "hexose catabolism" EXACT [] synonym: "hexose degradation" EXACT [] is_a: GO:0019318 ! hexose metabolic process is_a: GO:0046365 ! monosaccharide catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18133 ! hexose relationship: has_primary_input CHEBI:18133 ! hexose [Term] id: GO:0019336 name: phenol-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [ISBN:0198506732] synonym: "phenol-containing compound breakdown" EXACT [] synonym: "phenol-containing compound catabolism" EXACT [] synonym: "phenol-containing compound degradation" EXACT [] xref: MetaCyc:PHENOLDEG-PWY is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901616 ! organic hydroxy compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33853 ! phenols relationship: has_primary_input CHEBI:33853 ! phenols [Term] id: GO:0019413 name: acetate biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate anabolism" EXACT [] synonym: "acetate biosynthesis" EXACT [] synonym: "acetate formation" EXACT [] synonym: "acetate synthesis" EXACT [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072330 ! monocarboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:30089 ! acetate relationship: has_primary_output CHEBI:30089 ! acetate [Term] id: GO:0019438 name: aromatic compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] synonym: "aromatic compound anabolism" EXACT [] synonym: "aromatic compound biosynthesis" EXACT [] synonym: "aromatic compound formation" EXACT [] synonym: "aromatic compound synthesis" EXACT [] synonym: "aromatic hydrocarbon biosynthesis" NARROW [] synonym: "aromatic hydrocarbon biosynthetic process" NARROW [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33655 ! aromatic compound relationship: has_primary_output CHEBI:33655 ! aromatic compound [Term] id: GO:0019439 name: aromatic compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." [GOC:ai] synonym: "aromatic compound breakdown" EXACT [] synonym: "aromatic compound catabolism" EXACT [] synonym: "aromatic compound degradation" EXACT [] synonym: "aromatic hydrocarbon catabolic process" NARROW [] synonym: "aromatic hydrocarbon catabolism" NARROW [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0044248 ! cellular catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33655 ! aromatic compound relationship: has_primary_input CHEBI:33655 ! aromatic compound [Term] id: GO:0019538 name: protein metabolic process namespace: biological_process alt_id: GO:0006411 alt_id: GO:0044267 alt_id: GO:0044268 def: "The chemical reactions and pathways involving a protein. Includes protein modification." [GOC:ma] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_plant synonym: "cellular protein metabolic process" EXACT [] synonym: "cellular protein metabolism" EXACT [] synonym: "multicellular organismal protein metabolic process" NARROW [] synonym: "protein metabolic process and modification" EXACT [] synonym: "protein metabolism" EXACT [] synonym: "protein metabolism and modification" EXACT [] xref: Wikipedia:Protein_metabolism is_a: GO:0043170 ! macromolecule metabolic process is_a: GO:0044238 ! primary metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output PR:000000001 ! protein relationship: has_primary_input_or_output PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0019614 name: catechol-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." [GOC:go_curators] synonym: "catechol breakdown" RELATED [] synonym: "catechol catabolic process" RELATED [] synonym: "catechol catabolism" RELATED [] synonym: "catechol degradation" RELATED [] is_a: GO:0009712 ! catechol-containing compound metabolic process is_a: GO:0019336 ! phenol-containing compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33566 ! catechols relationship: has_primary_input CHEBI:33566 ! catechols [Term] id: GO:0019725 name: cellular homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state at the level of the cell." [GOC:isa_complete, GOC:jl, ISBN:0395825172] subset: goslim_candida subset: goslim_plant is_a: GO:0042592 ! homeostatic process intersection_of: GO:0042592 ! homeostatic process intersection_of: occurs_in CL:0000000 ! cell disjoint_from: GO:0048872 ! homeostasis of number of cells relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: occurs_in CL:0000000 ! cell relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0019748 name: secondary metabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." [GOC:go_curators] subset: goslim_chembl subset: goslim_pir subset: goslim_plant subset: goslim_pombe synonym: "secondary metabolism" EXACT [] synonym: "secondary metabolite metabolic process" EXACT [] synonym: "secondary metabolite metabolism" EXACT [] xref: Wikipedia:Secondary_metabolism is_a: GO:0008152 ! metabolic process [Term] id: GO:0019752 name: carboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "carboxylic acid metabolism" EXACT [] is_a: GO:0043436 ! oxoacid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input_or_output CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0019755 name: one-carbon compound transport namespace: biological_process def: "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "one carbon compound transport" EXACT [] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:64708 ! one-carbon compound relationship: has_primary_input CHEBI:64708 ! one-carbon compound [Term] id: GO:0019827 name: stem cell population maintenance namespace: biological_process def: "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." [GOC:mah, ISBN:0878932437] synonym: "maintenance of pluripotency" RELATED [GOC:vk] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0098727 ! maintenance of cell number intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000034 ! stem cell relationship: acts_on_population_of CL:0000034 ! stem cell [Term] id: GO:0019867 name: outer membrane namespace: cellular_component def: "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." [GOC:go_curators] subset: goslim_metagenomics is_a: GO:0016020 ! membrane [Term] id: GO:0019882 name: antigen processing and presentation namespace: biological_process alt_id: GO:0030333 def: "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." [GO_REF:0000022, GOC:add, ISBN:0781735149, PMID:15771591, PMID:15928678] synonym: "antigen presentation" EXACT [] synonym: "antigen processing" EXACT [] xref: Wikipedia:Antigen_presentation is_a: GO:0002376 ! immune system process [Term] id: GO:0019953 name: sexual reproduction namespace: biological_process def: "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." [Wikipedia:Sexual_reproduction] comment: Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. xref: Wikipedia:Sexual_reproduction is_a: GO:0000003 ! reproduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22929" xsd:anyURI [Term] id: GO:0021501 name: prechordal plate formation namespace: biological_process def: "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003063 ! prechordal plate relationship: part_of GO:0007399 ! nervous system development relationship: results_in_formation_of UBERON:0003063 ! prechordal plate [Term] id: GO:0021510 name: spinal cord development namespace: biological_process def: "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002240 ! spinal cord relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_development_of UBERON:0002240 ! spinal cord [Term] id: GO:0021514 name: ventral spinal cord interneuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: occurs_in UBERON:0002240 ! spinal cord intersection_of: results_in_acquisition_of_features_of CL:0000099 ! interneuron relationship: part_of GO:0021517 ! ventral spinal cord development relationship: results_in_acquisition_of_features_of CL:0000099 ! interneuron [Term] id: GO:0021515 name: cell differentiation in spinal cord namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: occurs_in UBERON:0002240 ! spinal cord relationship: occurs_in UBERON:0002240 ! spinal cord relationship: part_of GO:0021510 ! spinal cord development [Term] id: GO:0021517 name: ventral spinal cord development namespace: biological_process def: "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002257 ! ventral horn of spinal cord relationship: part_of GO:0021510 ! spinal cord development relationship: results_in_development_of UBERON:0002257 ! ventral horn of spinal cord [Term] id: GO:0021522 name: spinal cord motor neuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021515 ! cell differentiation in spinal cord is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0011001 ! spinal cord motor neuron relationship: part_of GO:0021517 ! ventral spinal cord development relationship: results_in_acquisition_of_features_of CL:0011001 ! spinal cord motor neuron [Term] id: GO:0021523 name: somatic motor neuron differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0021522 ! spinal cord motor neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0005024 ! somatomotor neuron relationship: results_in_acquisition_of_features_of CL:0005024 ! somatomotor neuron [Term] id: GO:0021532 name: neural tube patterning namespace: biological_process def: "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0003002 ! regionalization relationship: part_of GO:0021915 ! neural tube development [Term] id: GO:0021533 name: cell differentiation in hindbrain namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: occurs_in UBERON:0002028 ! hindbrain relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata relationship: occurs_in UBERON:0002028 ! hindbrain relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021534 name: cell proliferation in hindbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: occurs_in UBERON:0002028 ! hindbrain relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata relationship: occurs_in UBERON:0002028 ! hindbrain relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021535 name: cell migration in hindbrain namespace: biological_process def: "The orderly movement of a cell that will reside in the hindbrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: occurs_in UBERON:0002028 ! hindbrain relationship: in_taxon NCBITaxon:89593 {all_only="true"} ! Craniata relationship: occurs_in UBERON:0002028 ! hindbrain relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of GO:0030902 ! hindbrain development [Term] id: GO:0021537 name: telencephalon development namespace: biological_process def: "The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] synonym: "cerebrum development" EXACT [GOC:sl, PMID:22331407] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001893 ! telencephalon relationship: part_of GO:0030900 ! forebrain development relationship: results_in_development_of UBERON:0001893 ! telencephalon [Term] id: GO:0021543 name: pallium development namespace: biological_process def: "The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:12626695] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000203 ! pallium relationship: part_of GO:0021537 ! telencephalon development relationship: results_in_development_of UBERON:0000203 ! pallium [Term] id: GO:0021545 name: cranial nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021675 ! nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001785 ! cranial nerve relationship: results_in_development_of UBERON:0001785 ! cranial nerve [Term] id: GO:0021546 name: rhombomere development namespace: biological_process def: "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001892 ! rhombomere relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_development_of UBERON:0001892 ! rhombomere [Term] id: GO:0021547 name: midbrain-hindbrain boundary initiation namespace: biological_process def: "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:isa_complete, GOC:jid, PMID:15541513] synonym: "isthmus biosynthesis" RELATED [GOC:cls] synonym: "isthmus formation" RELATED [GOC:cls] synonym: "MHB biosynthesis" EXACT [GOC:cls] synonym: "MHB formation" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary biosynthesis" EXACT [GOC:cls] synonym: "midbrain-hindbrain boundary formation" EXACT [GOC:cls] is_a: GO:0003002 ! regionalization is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0021999 ! neural plate anterior/posterior regionalization relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: results_in_formation_of UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0021548 name: pons development namespace: biological_process def: "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000988 ! pons relationship: part_of GO:0022037 ! metencephalon development relationship: results_in_development_of UBERON:0000988 ! pons [Term] id: GO:0021550 name: medulla oblongata development namespace: biological_process def: "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla development" RELATED [GOC:cls] synonym: "myelencephalon development" RELATED [GOC:cls] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001896 ! medulla oblongata relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_development_of UBERON:0001896 ! medulla oblongata [Term] id: GO:0021551 name: central nervous system morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001017 ! central nervous system relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_morphogenesis_of UBERON:0001017 ! central nervous system [Term] id: GO:0021555 name: midbrain-hindbrain boundary morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] synonym: "isthmus morphogenesis" EXACT [GOC:cls] synonym: "MHB morphogenesis" EXACT [GOC:cls] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: results_in_morphogenesis_of UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0021556 name: central nervous system formation namespace: biological_process def: "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001017 ! central nervous system relationship: part_of GO:0021551 ! central nervous system morphogenesis relationship: results_in_formation_of UBERON:0001017 ! central nervous system [Term] id: GO:0021559 name: trigeminal nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V development" RELATED [GOC:cls] synonym: "cranial nerve 5 development" EXACT [GOC:cls] synonym: "cranial nerve V development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001645 ! trigeminal nerve relationship: results_in_development_of UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021561 name: facial nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII development" RELATED [GOC:cls] synonym: "cranial nerve 7 development" EXACT [GOC:cls] synonym: "cranial nerve VII development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001647 ! facial nerve relationship: part_of GO:0021783 ! preganglionic parasympathetic fiber development relationship: results_in_development_of UBERON:0001647 ! facial nerve [Term] id: GO:0021563 name: glossopharyngeal nerve development namespace: biological_process def: "Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX development" RELATED [GOC:cls] synonym: "cranial nerve 9 development" EXACT [GOC:cls] synonym: "cranial nerve IX development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001649 ! glossopharyngeal nerve relationship: results_in_development_of UBERON:0001649 ! glossopharyngeal nerve [Term] id: GO:0021564 name: vagus nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X development" RELATED [GOC:cls] synonym: "cranial nerve 10 development" RELATED [GOC:cls] synonym: "cranial nerve X development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001759 ! vagus nerve relationship: part_of GO:0021783 ! preganglionic parasympathetic fiber development relationship: results_in_development_of UBERON:0001759 ! vagus nerve [Term] id: GO:0021565 name: accessory nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI development" RELATED [GOC:cls] synonym: "cranial nerve 11 development" RELATED [GOC:cls] synonym: "cranial nerve XI development" EXACT [GOC:cls] synonym: "spinal accessory nerve development" EXACT [PMID:11533729] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002019 ! accessory XI nerve relationship: results_in_development_of UBERON:0002019 ! accessory XI nerve [Term] id: GO:0021566 name: hypoglossal nerve development namespace: biological_process def: "The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII development" RELATED [GOC:cls] synonym: "cranial nerve 12 development" RELATED [GOC:cls] synonym: "cranial nerve XII development" EXACT [GOC:cls] is_a: GO:0021545 ! cranial nerve development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001650 ! hypoglossal nerve relationship: results_in_development_of UBERON:0001650 ! hypoglossal nerve [Term] id: GO:0021575 name: hindbrain morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "rhombencephalon morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002028 ! hindbrain relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_morphogenesis_of UBERON:0002028 ! hindbrain [Term] id: GO:0021576 name: hindbrain formation namespace: biological_process def: "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002028 ! hindbrain relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: results_in_formation_of UBERON:0002028 ! hindbrain [Term] id: GO:0021578 name: hindbrain maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0002028 ! hindbrain relationship: part_of GO:0021626 ! central nervous system maturation relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_maturation_of UBERON:0002028 ! hindbrain [Term] id: GO:0021579 name: medulla oblongata morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla morphogenesis" RELATED [] synonym: "myelencephalon morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001896 ! medulla oblongata relationship: part_of GO:0021550 ! medulla oblongata development relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: results_in_morphogenesis_of UBERON:0001896 ! medulla oblongata [Term] id: GO:0021580 name: medulla oblongata formation namespace: biological_process def: "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla biosynthesis" RELATED [] synonym: "medulla formation" RELATED [] synonym: "myelencephalon biosynthesis" RELATED [] synonym: "myelencephalon formation" RELATED [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001896 ! medulla oblongata relationship: part_of GO:0021576 ! hindbrain formation relationship: part_of GO:0021579 ! medulla oblongata morphogenesis relationship: results_in_formation_of UBERON:0001896 ! medulla oblongata [Term] id: GO:0021582 name: medulla oblongata maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "medulla maturation" RELATED [] synonym: "myelencephalon maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001896 ! medulla oblongata relationship: part_of GO:0021550 ! medulla oblongata development relationship: part_of GO:0021578 ! hindbrain maturation relationship: results_in_maturation_of UBERON:0001896 ! medulla oblongata [Term] id: GO:0021583 name: pons morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000988 ! pons relationship: part_of GO:0021548 ! pons development relationship: part_of GO:0021575 ! hindbrain morphogenesis relationship: results_in_morphogenesis_of UBERON:0000988 ! pons [Term] id: GO:0021584 name: pons formation namespace: biological_process def: "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000988 ! pons relationship: part_of GO:0021576 ! hindbrain formation relationship: part_of GO:0021583 ! pons morphogenesis relationship: results_in_formation_of UBERON:0000988 ! pons [Term] id: GO:0021586 name: pons maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0000988 ! pons relationship: part_of GO:0021548 ! pons development relationship: part_of GO:0021578 ! hindbrain maturation relationship: results_in_maturation_of UBERON:0000988 ! pons [Term] id: GO:0021593 name: rhombomere morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001892 ! rhombomere relationship: part_of GO:0021546 ! rhombomere development relationship: results_in_morphogenesis_of UBERON:0001892 ! rhombomere [Term] id: GO:0021594 name: rhombomere formation namespace: biological_process def: "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001892 ! rhombomere relationship: part_of GO:0021593 ! rhombomere morphogenesis relationship: results_in_formation_of UBERON:0001892 ! rhombomere [Term] id: GO:0021602 name: cranial nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001785 ! cranial nerve relationship: part_of GO:0021545 ! cranial nerve development relationship: results_in_morphogenesis_of UBERON:0001785 ! cranial nerve [Term] id: GO:0021603 name: cranial nerve formation namespace: biological_process def: "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001785 ! cranial nerve relationship: part_of GO:0021602 ! cranial nerve morphogenesis relationship: results_in_formation_of UBERON:0001785 ! cranial nerve [Term] id: GO:0021605 name: cranial nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0021682 ! nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001785 ! cranial nerve relationship: part_of GO:0021545 ! cranial nerve development relationship: results_in_maturation_of UBERON:0001785 ! cranial nerve [Term] id: GO:0021606 name: accessory nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI maturation" RELATED [] synonym: "spinal accessory nerve maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0002019 ! accessory XI nerve relationship: part_of GO:0021565 ! accessory nerve development relationship: results_in_maturation_of UBERON:0002019 ! accessory XI nerve [Term] id: GO:0021607 name: accessory nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002019 ! accessory XI nerve relationship: part_of GO:0021565 ! accessory nerve development relationship: results_in_morphogenesis_of UBERON:0002019 ! accessory XI nerve [Term] id: GO:0021608 name: accessory nerve formation namespace: biological_process def: "The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XI biosynthesis" RELATED [] synonym: "CN XI formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002019 ! accessory XI nerve relationship: part_of GO:0021607 ! accessory nerve morphogenesis relationship: results_in_formation_of UBERON:0002019 ! accessory XI nerve [Term] id: GO:0021610 name: facial nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001647 ! facial nerve relationship: part_of GO:0021561 ! facial nerve development relationship: results_in_morphogenesis_of UBERON:0001647 ! facial nerve [Term] id: GO:0021611 name: facial nerve formation namespace: biological_process def: "The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII biosynthesis" RELATED [] synonym: "CN VII formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001647 ! facial nerve relationship: part_of GO:0021610 ! facial nerve morphogenesis relationship: results_in_formation_of UBERON:0001647 ! facial nerve [Term] id: GO:0021613 name: facial nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN VII maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001647 ! facial nerve relationship: part_of GO:0021561 ! facial nerve development relationship: results_in_maturation_of UBERON:0001647 ! facial nerve [Term] id: GO:0021614 name: glossopharyngeal nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001649 ! glossopharyngeal nerve relationship: part_of GO:0021563 ! glossopharyngeal nerve development relationship: results_in_maturation_of UBERON:0001649 ! glossopharyngeal nerve [Term] id: GO:0021615 name: glossopharyngeal nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001649 ! glossopharyngeal nerve relationship: part_of GO:0021563 ! glossopharyngeal nerve development relationship: results_in_morphogenesis_of UBERON:0001649 ! glossopharyngeal nerve [Term] id: GO:0021616 name: glossopharyngeal nerve formation namespace: biological_process def: "The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN IX biosynthesis" RELATED [] synonym: "CN IX formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001649 ! glossopharyngeal nerve relationship: part_of GO:0021615 ! glossopharyngeal nerve morphogenesis relationship: results_in_formation_of UBERON:0001649 ! glossopharyngeal nerve [Term] id: GO:0021618 name: hypoglossal nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001650 ! hypoglossal nerve relationship: part_of GO:0021566 ! hypoglossal nerve development relationship: results_in_morphogenesis_of UBERON:0001650 ! hypoglossal nerve [Term] id: GO:0021619 name: hypoglossal nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001650 ! hypoglossal nerve relationship: part_of GO:0021566 ! hypoglossal nerve development relationship: results_in_maturation_of UBERON:0001650 ! hypoglossal nerve [Term] id: GO:0021620 name: hypoglossal nerve formation namespace: biological_process def: "The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN XII biosynthesis" RELATED [] synonym: "CN XII formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001650 ! hypoglossal nerve relationship: part_of GO:0021618 ! hypoglossal nerve morphogenesis relationship: results_in_formation_of UBERON:0001650 ! hypoglossal nerve [Term] id: GO:0021626 name: central nervous system maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0582227089] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001017 ! central nervous system relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_maturation_of UBERON:0001017 ! central nervous system [Term] id: GO:0021635 name: trigeminal nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001645 ! trigeminal nerve relationship: part_of GO:0021559 ! trigeminal nerve development relationship: results_in_maturation_of UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021636 name: trigeminal nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001645 ! trigeminal nerve relationship: part_of GO:0021559 ! trigeminal nerve development relationship: results_in_morphogenesis_of UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021638 name: trigeminal nerve formation namespace: biological_process def: "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN V biosynthesis" RELATED [] synonym: "CN V formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001645 ! trigeminal nerve relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis relationship: results_in_formation_of UBERON:0001645 ! trigeminal nerve [Term] id: GO:0021643 name: vagus nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X maturation" RELATED [] is_a: GO:0021605 ! cranial nerve maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001759 ! vagus nerve relationship: part_of GO:0021564 ! vagus nerve development relationship: results_in_maturation_of UBERON:0001759 ! vagus nerve [Term] id: GO:0021644 name: vagus nerve morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X morphogenesis" RELATED [] is_a: GO:0021602 ! cranial nerve morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001759 ! vagus nerve relationship: part_of GO:0021564 ! vagus nerve development relationship: results_in_morphogenesis_of UBERON:0001759 ! vagus nerve [Term] id: GO:0021646 name: vagus nerve formation namespace: biological_process def: "The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "CN X biosynthesis" RELATED [] synonym: "CN X formation" RELATED [] is_a: GO:0021603 ! cranial nerve formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001759 ! vagus nerve relationship: part_of GO:0021644 ! vagus nerve morphogenesis relationship: results_in_formation_of UBERON:0001759 ! vagus nerve [Term] id: GO:0021654 name: rhombomere boundary formation namespace: biological_process def: "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0018239 ! rhombomere boundary relationship: part_of GO:0021594 ! rhombomere formation relationship: results_in_formation_of UBERON:0018239 ! rhombomere boundary [Term] id: GO:0021675 name: nerve development namespace: biological_process def: "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001021 ! nerve relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0001021 ! nerve [Term] id: GO:0021682 name: nerve maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001021 ! nerve relationship: part_of GO:0021675 ! nerve development relationship: results_in_maturation_of UBERON:0001021 ! nerve [Term] id: GO:0021700 name: developmental maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] subset: goslim_chembl is_a: GO:0032502 ! developmental process [Term] id: GO:0021703 name: locus ceruleus development namespace: biological_process def: "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "locus caeruleus development" EXACT [] synonym: "locus coeruleus development" EXACT [] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021548 ! pons development relationship: results_in_development_of UBERON:0002148 ! locus ceruleus [Term] id: GO:0021704 name: locus ceruleus morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021583 ! pons morphogenesis relationship: part_of GO:0021703 ! locus ceruleus development relationship: results_in_morphogenesis_of UBERON:0002148 ! locus ceruleus [Term] id: GO:0021705 name: locus ceruleus formation namespace: biological_process def: "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021584 ! pons formation relationship: part_of GO:0021704 ! locus ceruleus morphogenesis relationship: results_in_formation_of UBERON:0002148 ! locus ceruleus [Term] id: GO:0021706 name: locus ceruleus maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0002148 ! locus ceruleus relationship: part_of GO:0021586 ! pons maturation relationship: part_of GO:0021703 ! locus ceruleus development relationship: results_in_maturation_of UBERON:0002148 ! locus ceruleus [Term] id: GO:0021718 name: superior olivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive development" RELATED [] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021548 ! pons development relationship: results_in_development_of UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021719 name: superior olivary nucleus morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive morphogenesis" RELATED [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021583 ! pons morphogenesis relationship: part_of GO:0021718 ! superior olivary nucleus development relationship: results_in_morphogenesis_of UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021720 name: superior olivary nucleus formation namespace: biological_process def: "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021584 ! pons formation relationship: part_of GO:0021719 ! superior olivary nucleus morphogenesis relationship: results_in_formation_of UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021722 name: superior olivary nucleus maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0838580343] synonym: "superior olive maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0007247 ! nucleus of superior olivary complex relationship: part_of GO:0021586 ! pons maturation relationship: part_of GO:0021718 ! superior olivary nucleus development relationship: results_in_maturation_of UBERON:0007247 ! nucleus of superior olivary complex [Term] id: GO:0021732 name: midbrain-hindbrain boundary maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15541513] synonym: "isthmus maturation" RELATED [] synonym: "MHB maturation" RELATED [] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0030917 ! midbrain-hindbrain boundary development relationship: results_in_maturation_of UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0021743 name: hypoglossal nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002871 ! hypoglossal nucleus relationship: part_of GO:0021550 ! medulla oblongata development relationship: results_in_development_of UBERON:0002871 ! hypoglossal nucleus [Term] id: GO:0021751 name: salivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004133 ! salivatory nucleus relationship: part_of GO:0021548 ! pons development relationship: results_in_development_of UBERON:0004133 ! salivatory nucleus [Term] id: GO:0021753 name: superior salivary nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021751 ! salivary nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002149 ! superior salivatory nucleus relationship: results_in_development_of UBERON:0002149 ! superior salivatory nucleus [Term] id: GO:0021754 name: facial nucleus development namespace: biological_process def: "The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048857 ! neural nucleus development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000127 ! facial nucleus relationship: part_of GO:0021548 ! pons development relationship: results_in_development_of UBERON:0000127 ! facial nucleus [Term] id: GO:0021782 name: glial cell development namespace: biological_process def: "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000125 ! glial cell relationship: part_of GO:0010001 ! glial cell differentiation relationship: results_in_development_of CL:0000125 ! glial cell [Term] id: GO:0021783 name: preganglionic parasympathetic fiber development namespace: biological_process def: "The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion." [GO_REF:0000021, GOC:cjm, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0011930 ! preganglionic parasympathetic fiber relationship: part_of GO:0007417 ! central nervous system development relationship: part_of GO:0048486 ! parasympathetic nervous system development relationship: results_in_development_of UBERON:0011930 ! preganglionic parasympathetic fiber [Term] id: GO:0021846 name: cell proliferation in forebrain namespace: biological_process def: "The creation of greater cell numbers in the forebrain due to cell division of progenitor cells." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: occurs_in UBERON:0001890 ! forebrain relationship: occurs_in UBERON:0001890 ! forebrain relationship: part_of GO:0030900 ! forebrain development [Term] id: GO:0021863 name: forebrain neuroblast differentiation namespace: biological_process def: "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] synonym: "abventricular progenitor cell differentiation" EXACT [PMID:16226447] synonym: "intermediate progenitor cell differentiation" EXACT [PMID:16226447] synonym: "non-surface dividing progenitor cell differentiation" EXACT [PMID:16226447] is_a: GO:0014016 ! neuroblast differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000042 ! forebrain neuroblast relationship: part_of GO:0021872 ! forebrain generation of neurons relationship: results_in_acquisition_of_features_of CL:1000042 ! forebrain neuroblast [Term] id: GO:0021872 name: forebrain generation of neurons namespace: biological_process def: "The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "generation of neurons in forebrain" EXACT [] is_a: GO:0048699 ! generation of neurons relationship: part_of GO:0030900 ! forebrain development [Term] id: GO:0021879 name: forebrain neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:16226447] is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0012001 ! neuron of the forebrain relationship: part_of GO:0021872 ! forebrain generation of neurons relationship: results_in_acquisition_of_features_of CL:0012001 ! neuron of the forebrain [Term] id: GO:0021884 name: forebrain neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021954 ! central nervous system neuron development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0012001 ! neuron of the forebrain relationship: part_of GO:0021879 ! forebrain neuron differentiation relationship: results_in_development_of CL:0012001 ! neuron of the forebrain [Term] id: GO:0021885 name: forebrain cell migration namespace: biological_process def: "The orderly movement of a cell from one site to another at least one of which is located in the forebrain." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0016477 ! cell migration relationship: part_of GO:0030900 ! forebrain development [Term] id: GO:0021895 name: cerebral cortex neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021953 ! central nervous system neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010012 ! cerebral cortex neuron relationship: part_of GO:0030900 ! forebrain development relationship: results_in_acquisition_of_features_of CL:0010012 ! cerebral cortex neuron [Term] id: GO:0021903 name: rostrocaudal neural tube patterning namespace: biological_process def: "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] synonym: "anterior-posterior neural tube patterning" RELATED [GOC:dph] is_a: GO:0009952 ! anterior/posterior pattern specification relationship: part_of GO:0021532 ! neural tube patterning [Term] id: GO:0021905 name: forebrain-midbrain boundary formation namespace: biological_process def: "The process whose specific outcome is the creation of the forebrain-midbrain boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0048856 ! anatomical structure development is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005075 ! forebrain-midbrain boundary relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: results_in_formation_of UBERON:0005075 ! forebrain-midbrain boundary [Term] id: GO:0021906 name: hindbrain-spinal cord boundary formation namespace: biological_process def: "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:11262869] is_a: GO:0048859 ! formation of anatomical boundary intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005076 ! hindbrain-spinal cord boundary relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: results_in_formation_of UBERON:0005076 ! hindbrain-spinal cord boundary [Term] id: GO:0021915 name: neural tube development namespace: biological_process def: "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001049 ! neural tube relationship: part_of GO:0007399 ! nervous system development relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_development_of UBERON:0001049 ! neural tube [Term] id: GO:0021953 name: central nervous system neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000029 ! central nervous system neuron relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_acquisition_of_features_of CL:2000029 ! central nervous system neuron [Term] id: GO:0021954 name: central nervous system neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:2000029 ! central nervous system neuron relationship: part_of GO:0021953 ! central nervous system neuron differentiation relationship: results_in_development_of CL:2000029 ! central nervous system neuron [Term] id: GO:0021987 name: cerebral cortex development namespace: biological_process def: "The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "corticogenesis" NARROW [GOC:bf, PMID:25904839] synonym: "neocortex development" RELATED [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000956 ! cerebral cortex relationship: part_of GO:0021543 ! pallium development relationship: results_in_development_of UBERON:0000956 ! cerebral cortex [Term] id: GO:0021990 name: neural plate formation namespace: biological_process def: "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, ISBN:0878932437, ISBN:0878932585, PMID:15806586] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003075 ! neural plate relationship: part_of GO:0001839 ! neural plate morphogenesis relationship: results_in_formation_of UBERON:0003075 ! neural plate [Term] id: GO:0021999 name: neural plate anterior/posterior regionalization namespace: biological_process def: "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "neural plate anterior/posterior pattern formation" RELATED [GOC:dph] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0060897 ! neural plate regionalization [Term] id: GO:0022008 name: neurogenesis namespace: biological_process def: "Generation of cells within the nervous system." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] synonym: "nervous system cell generation" EXACT systematic_synonym [] synonym: "neural cell differentiation" RELATED [GOC:BHF, GOC:dph] xref: Wikipedia:Neurogenesis is_a: GO:0030154 ! cell differentiation relationship: part_of GO:0007399 ! nervous system development [Term] id: GO:0022009 name: central nervous system vasculogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: results_in_maturation_of UBERON:0001017 ! central nervous system relationship: results_in_maturation_of UBERON:0001017 ! central nervous system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21480" xsd:anyURI [Term] id: GO:0022010 name: central nervous system myelination namespace: biological_process def: "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "myelination in central nervous system" EXACT [] is_a: GO:0032291 ! axon ensheathment in central nervous system is_a: GO:0042552 ! myelination intersection_of: GO:0042552 ! myelination intersection_of: occurs_in UBERON:0001017 ! central nervous system relationship: in_taxon NCBITaxon:33213 {all_only="true"} ! Bilateria relationship: part_of GO:0014003 ! oligodendrocyte development [Term] id: GO:0022011 name: myelination in peripheral nervous system namespace: biological_process def: "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] synonym: "peripheral nervous system myelination" EXACT [] is_a: GO:0032292 ! peripheral nervous system axon ensheathment is_a: GO:0042552 ! myelination intersection_of: GO:0042552 ! myelination intersection_of: occurs_in UBERON:0000010 ! peripheral nervous system relationship: part_of GO:0014044 ! Schwann cell development [Term] id: GO:0022029 name: telencephalon cell migration namespace: biological_process def: "The orderly movement of a cell from one site to another at least one of which is located in the telencephalon." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0021885 ! forebrain cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_transport_to_from_or_in UBERON:0001893 ! telencephalon relationship: part_of GO:0021537 ! telencephalon development relationship: results_in_transport_to_from_or_in UBERON:0001893 ! telencephalon [Term] id: GO:0022030 name: telencephalon glial cell migration namespace: biological_process def: "The orderly movement of glial cells through the telencephalon." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0008347 ! glial cell migration is_a: GO:0022029 ! telencephalon cell migration intersection_of: GO:0008347 ! glial cell migration intersection_of: results_in_transport_to_from_or_in UBERON:0001893 ! telencephalon [Term] id: GO:0022032 name: telencephalon oligodendrocyte cell migration namespace: biological_process def: "The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0022030 ! telencephalon glial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: has_primary_input CL:0000128 ! oligodendrocyte intersection_of: results_in_transport_to_from_or_in UBERON:0001893 ! telencephalon relationship: has_primary_input CL:0000128 ! oligodendrocyte [Term] id: GO:0022035 name: rhombomere cell migration namespace: biological_process def: "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15629700] is_a: GO:0021535 ! cell migration in hindbrain intersection_of: GO:0016477 ! cell migration intersection_of: results_in_transport_to_from_or_in UBERON:0001892 ! rhombomere relationship: part_of GO:0021546 ! rhombomere development relationship: results_in_transport_to_from_or_in UBERON:0001892 ! rhombomere [Term] id: GO:0022037 name: metencephalon development namespace: biological_process def: "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." [GO_REF:0000021, GOC:cls, GOC:curators, GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001895 ! metencephalon relationship: part_of GO:0030902 ! hindbrain development relationship: results_in_development_of UBERON:0001895 ! metencephalon [Term] id: GO:0022402 name: cell cycle process namespace: biological_process def: "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." [GOC:isa_complete, GOC:mtg_cell_cycle] subset: gocheck_do_not_annotate is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0007049 ! cell cycle relationship: part_of GO:0007049 ! cell cycle [Term] id: GO:0022406 name: membrane docking namespace: biological_process def: "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere." [GOC:isa_complete, PMID:27875684] subset: goslim_pir is_a: GO:0009987 ! cellular process [Term] id: GO:0022407 name: regulation of cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." [GOC:isa_complete] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098609 ! cell-cell adhesion relationship: regulates GO:0098609 ! cell-cell adhesion [Term] id: GO:0022408 name: negative regulation of cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "down regulation of cell-cell adhesion" EXACT [] synonym: "down-regulation of cell-cell adhesion" EXACT [] synonym: "downregulation of cell-cell adhesion" EXACT [] synonym: "inhibition of cell-cell adhesion" NARROW [] is_a: GO:0007162 ! negative regulation of cell adhesion is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098609 ! cell-cell adhesion relationship: negatively_regulates GO:0098609 ! cell-cell adhesion [Term] id: GO:0022409 name: positive regulation of cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the rate or extent of cell adhesion to another cell." [GOC:isa_complete] synonym: "activation of cell-cell adhesion" NARROW [] synonym: "stimulation of cell-cell adhesion" NARROW [] synonym: "up regulation of cell-cell adhesion" EXACT [] synonym: "up-regulation of cell-cell adhesion" EXACT [] synonym: "upregulation of cell-cell adhesion" EXACT [] is_a: GO:0022407 ! regulation of cell-cell adhesion is_a: GO:0045785 ! positive regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098609 ! cell-cell adhesion relationship: positively_regulates GO:0098609 ! cell-cell adhesion [Term] id: GO:0022411 name: cellular component disassembly namespace: biological_process alt_id: GO:0071845 def: "A cellular process that results in the breakdown of a cellular component." [GOC:isa_complete] subset: goslim_pir synonym: "cell structure disassembly" EXACT [] synonym: "cellular component disassembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_disassembly_of GO:0005575 ! cellular_component disjoint_from: GO:0022607 ! cellular component assembly relationship: results_in_disassembly_of GO:0005575 ! cellular_component [Term] id: GO:0022412 name: cellular process involved in reproduction in multicellular organism namespace: biological_process def: "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." [GOC:isa_complete] synonym: "reproductive cellular process in multicellular organism" EXACT [] is_a: GO:0009987 ! cellular process is_a: GO:0022414 ! reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0032504 ! multicellular organism reproduction relationship: part_of GO:0032504 ! multicellular organism reproduction [Term] id: GO:0022414 name: reproductive process namespace: biological_process alt_id: GO:0044702 def: "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:dph, GOC:isa_complete] subset: goslim_generic synonym: "single organism reproductive process" RELATED [] is_a: GO:0008150 ! biological_process intersection_of: GO:0008150 ! biological_process intersection_of: part_of GO:0000003 ! reproduction relationship: part_of GO:0000003 ! reproduction created_by: jl creation_date: 2012-09-19T15:56:06Z [Term] id: GO:0022600 name: digestive system process namespace: biological_process def: "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:isa_complete, GOC:jid, GOC:mtg_cardio] subset: goslim_generic is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: part_of GO:0007586 ! digestion relationship: part_of GO:0007586 ! digestion [Term] id: GO:0022602 name: ovulation cycle process namespace: biological_process def: "A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [GOC:isa_complete] synonym: "estrous cycle process" RELATED [] synonym: "menstrual cycle process" RELATED [] is_a: GO:0022414 ! reproductive process is_a: GO:0048511 ! rhythmic process intersection_of: GO:0008150 ! biological_process intersection_of: part_of GO:0042698 ! ovulation cycle relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0042698 ! ovulation cycle [Term] id: GO:0022603 name: regulation of anatomical structure morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." [GOC:mah] synonym: "regulation of morphogenesis" EXACT [] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009653 ! anatomical structure morphogenesis relationship: regulates GO:0009653 ! anatomical structure morphogenesis [Term] id: GO:0022604 name: regulation of cell morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." [GOC:isa_complete] synonym: "negative regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] synonym: "regulation of cell shape and cell size" RELATED [GOC:dph, GOC:tb] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000902 ! cell morphogenesis relationship: regulates GO:0000902 ! cell morphogenesis [Term] id: GO:0022607 name: cellular component assembly namespace: biological_process alt_id: GO:0071844 def: "The aggregation, arrangement and bonding together of a cellular component." [GOC:isa_complete] subset: goslim_chembl subset: goslim_pir synonym: "cell structure assembly" EXACT [] synonym: "cellular component assembly at cellular level" EXACT [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0005575 ! cellular_component relationship: part_of GO:0044085 ! cellular component biogenesis relationship: results_in_assembly_of GO:0005575 ! cellular_component [Term] id: GO:0022612 name: gland morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a gland are generated and organized." [GOC:isa_complete] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002530 ! gland relationship: part_of GO:0048732 ! gland development relationship: results_in_morphogenesis_of UBERON:0002530 ! gland [Term] id: GO:0022613 name: ribonucleoprotein complex biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." [GOC:isa_complete, GOC:mah] synonym: "ribonucleoprotein complex biogenesis and assembly" EXACT [GOC:mah] synonym: "RNA-protein complex biogenesis" EXACT [GOC:mah] is_a: GO:0044085 ! cellular component biogenesis [Term] id: GO:0022617 name: extracellular matrix disassembly namespace: biological_process def: "A process that results in the breakdown of the extracellular matrix." [GOC:jid] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0031012 ! extracellular matrix relationship: results_in_disassembly_of GO:0031012 ! extracellular matrix [Term] id: GO:0022618 name: protein-RNA complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." [GOC:jl] subset: goslim_chembl synonym: "ribonucleoprotein complex assembly" EXACT [] synonym: "RNA-protein complex assembly" EXACT [] synonym: "RNP complex assembly" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:1990904 ! ribonucleoprotein complex relationship: part_of GO:0022613 ! ribonucleoprotein complex biogenesis relationship: results_in_assembly_of GO:1990904 ! ribonucleoprotein complex [Term] id: GO:0022804 name: active transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] synonym: "active carrier activity" EXACT [] synonym: "carrier activity" EXACT [] synonym: "permease activity" EXACT [] synonym: "pump activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity [Term] id: GO:0022853 name: active monoatomic ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." [GOC:mtg_transport, ISBN:0815340729] synonym: "active ion transmembrane transporter activity" BROAD [] is_a: GO:0015075 ! monoatomic ion transmembrane transporter activity is_a: GO:0022804 ! active transmembrane transporter activity intersection_of: GO:0022804 ! active transmembrane transporter activity intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24479" xsd:anyURI [Term] id: GO:0022857 name: transmembrane transporter activity namespace: molecular_function alt_id: GO:0005386 alt_id: GO:0015563 alt_id: GO:0015646 alt_id: GO:0022891 alt_id: GO:0022892 def: "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." [GOC:jid, GOC:mtg_transport, ISBN:0815340729] subset: goslim_chembl subset: goslim_drosophila subset: goslim_yeast synonym: "substrate-specific transmembrane transporter activity" RELATED [] synonym: "substrate-specific transporter activity" RELATED [] synonym: "uptake permease activity" RELATED [] synonym: "uptake transmembrane transporter activity" RELATED [] xref: Reactome:R-HSA-1236947 "Egress of internalized antigen to the cytosol via sec61" xref: Reactome:R-HSA-429036 "SLC2A9 transports Fru, Glc, urate" xref: Reactome:R-HSA-5638209 "Defective SLC2A9 does not transport Fru, Glc, urate" xref: Reactome:R-HSA-5671707 "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA" xref: Reactome:R-HSA-6784434 "An unknown carrier transports cytosolic glyoxylate to the peroxisome" xref: Reactome:R-HSA-6784436 "An unknown carrier transports mitochondrial glyoxylate to the cytosol" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: part_of GO:0055085 ! transmembrane transport relationship: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0022884 name: macromolecule transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a macromolecule from one side of a membrane to the other." [GOC:mtg_transport, ISBN:0815340729] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33694 ! biomacromolecule relationship: has_primary_input CHEBI:33694 ! biomacromolecule [Term] id: GO:0022890 name: inorganic cation transmembrane transporter activity namespace: molecular_function alt_id: GO:0015077 alt_id: GO:0015082 alt_id: GO:0072509 alt_id: GO:0072510 def: "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "di-, tri-valent inorganic cation transmembrane transporter activity" NARROW [GOC:mah] synonym: "divalent inorganic cation transmembrane transporter activity" NARROW [] synonym: "monovalent inorganic cation transmembrane transporter activity" NARROW [] synonym: "trivalent inorganic cation transmembrane transporter activity" NARROW [] is_a: GO:0015318 ! inorganic molecular entity transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:36915 ! inorganic cation relationship: has_primary_input CHEBI:36915 ! inorganic cation [Term] id: GO:0022898 name: regulation of transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." [GOC:dph, GOC:mtg_cardio, GOC:mtg_transport] subset: term_scheduled_for_obsoletion is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022857 ! transmembrane transporter activity relationship: regulates GO:0022857 ! transmembrane transporter activity [Term] id: GO:0023019 name: signal transduction involved in regulation of gene expression namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." [GOC:mtg_signal] synonym: "regulation of gene expression as a consequence of signal transmission" RELATED [GOC:bf] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: part_of GO:0010468 ! regulation of gene expression relationship: part_of GO:0010468 ! regulation of gene expression creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023051 name: regulation of signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "regulation of signaling process" RELATED [GOC:bf] synonym: "regulation of signalling process" RELATED [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0023052 ! signaling relationship: regulates GO:0023052 ! signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023052 name: signaling namespace: biological_process alt_id: GO:0023046 alt_id: GO:0044700 def: "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_mouse subset: goslim_pombe subset: goslim_yeast subset: prokaryote_subset synonym: "biological signaling" EXACT [] synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] synonym: "signalling process" RELATED [GOC:mah] synonym: "single organism signaling" RELATED [] is_a: GO:0050789 ! regulation of biological process created_by: jl creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023056 name: positive regulation of signaling namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "positive regulation of signaling process" RELATED [GOC:bf] synonym: "positive regulation of signalling process" EXACT [GOC:mah] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0023052 ! signaling relationship: positively_regulates GO:0023052 ! signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023057 name: negative regulation of signaling namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." [GOC:mtg_signal] synonym: "negative regulation of signaling process" RELATED [GOC:bf] synonym: "negative regulation of signalling process" RELATED [GOC:mah] is_a: GO:0023051 ! regulation of signaling is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0023052 ! signaling relationship: negatively_regulates GO:0023052 ! signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0023061 name: signal release namespace: biological_process def: "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." [GOC:mtg_signal] synonym: "signal secretion" EXACT [GOC:bf] is_a: GO:0032940 ! secretion by cell intersection_of: GO:0032940 ! secretion by cell intersection_of: part_of GO:0007267 ! cell-cell signaling relationship: part_of GO:0007267 ! cell-cell signaling creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0030001 name: metal ion transport namespace: biological_process alt_id: GO:0070838 alt_id: GO:0070839 def: "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "divalent metal ion export" NARROW [] synonym: "divalent metal ion transport" NARROW [] synonym: "heavy metal ion transport" NARROW [] synonym: "metal ion export" NARROW [] is_a: GO:0006812 ! monoatomic cation transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:25213 ! metal cation relationship: has_primary_input CHEBI:25213 ! metal cation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23033" xsd:anyURI created_by: mah creation_date: 2009-07-31T01:07:46Z [Term] id: GO:0030010 name: establishment of cell polarity namespace: biological_process alt_id: GO:0000283 alt_id: GO:0030468 def: "The specification and formation of anisotropic intracellular organization or cell growth patterns." [GOC:mah] synonym: "bud site selection/establishment of cell polarity" NARROW [] synonym: "cell polarization" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030016 name: myofibril namespace: cellular_component def: "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." [ISBN:0815316194] xref: Wikipedia:Myofibril is_a: GO:0043292 ! contractile fiber intersection_of: GO:0043292 ! contractile fiber intersection_of: part_of CL:0000737 ! striated muscle cell relationship: part_of CL:0000737 ! striated muscle cell [Term] id: GO:0030017 name: sarcomere namespace: cellular_component def: "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [ISBN:0815316194] xref: Wikipedia:Sarcomere is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0030016 ! myofibril [Term] id: GO:0030029 name: actin filament-based process namespace: biological_process def: "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." [GOC:mah] synonym: "microfilament-based process" RELATED [] is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: process_has_causal_agent GO:0005884 ! actin filament relationship: process_has_causal_agent GO:0005884 ! actin filament [Term] id: GO:0030030 name: cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] subset: prokaryote_subset synonym: "cell projection organisation" EXACT [] synonym: "cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "cell surface structure organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0042995 ! cell projection relationship: results_in_organization_of GO:0042995 ! cell projection [Term] id: GO:0030031 name: cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, GOC:mah, http://www.cogsci.princeton.edu/~wn/] synonym: "cell projection biogenesis" RELATED [GOC:mah] synonym: "formation of a cell surface projection" EXACT [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030030 ! cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0042995 ! cell projection relationship: results_in_assembly_of GO:0042995 ! cell projection [Term] id: GO:0030033 name: microvillus assembly namespace: biological_process def: "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah, ISBN:0815316194] synonym: "microvillus biogenesis" RELATED [GOC:mah] is_a: GO:0032528 ! microvillus organization is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005902 ! microvillus relationship: results_in_assembly_of GO:0005902 ! microvillus [Term] id: GO:0030036 name: actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_pombe synonym: "actin cytoskeleton organisation" EXACT [] synonym: "actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] synonym: "actin modulating activity" RELATED [] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0030029 ! actin filament-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0015629 ! actin cytoskeleton relationship: results_in_organization_of GO:0015629 ! actin cytoskeleton property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23114" xsd:anyURI [Term] id: GO:0030048 name: actin filament-based movement namespace: biological_process def: "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." [GOC:BHF, GOC:mah] is_a: GO:0030029 ! actin filament-based process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0030050 name: vesicle transport along actin filament namespace: biological_process def: "Movement of a vesicle along an actin filament, mediated by motor proteins." [GOC:mah] is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0031982 ! vesicle intersection_of: results_in_transport_along GO:0005884 ! actin filament [Term] id: GO:0030054 name: cell junction namespace: cellular_component def: "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." [GOC:aruk, GOC:bc, GOC:mah, http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html, ISBN:0198506732, PMID:26820516, PMID:28096264] subset: goslim_agr subset: goslim_drosophila subset: goslim_flybase_ribbon xref: Wikipedia:Cell_junction is_a: GO:0110165 ! cellular anatomical entity property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0030072 name: peptide hormone secretion namespace: biological_process def: "The regulated release of a peptide hormone from a cell." [GOC:mah] is_a: GO:0002790 ! peptide secretion is_a: GO:0046879 ! hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:25905 ! peptide hormone relationship: has_primary_input CHEBI:25905 ! peptide hormone [Term] id: GO:0030073 name: insulin secretion namespace: biological_process def: "The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." [GOC:mah, ISBN:0198506732] is_a: GO:0009306 ! protein secretion is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input PR:000009054 ! insulin gene translation product relationship: has_primary_input PR:000009054 ! insulin gene translation product relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045" xsd:anyURI [Term] id: GO:0030097 name: hemopoiesis namespace: biological_process def: "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." [GOC:dgh, ISBN:0198506732] synonym: "blood cell biosynthesis" EXACT [] synonym: "blood cell formation" EXACT [] synonym: "haemopoiesis" EXACT [] synonym: "hematopoiesis" EXACT [] xref: Wikipedia:Haematopoiesis is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000988 ! hematopoietic cell relationship: results_in_development_of CL:0000988 ! hematopoietic cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22178" xsd:anyURI [Term] id: GO:0030098 name: lymphocyte differentiation namespace: biological_process alt_id: GO:0046650 def: "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "lymphocyte cell differentiation" EXACT [] synonym: "lymphocyte development" RELATED [GOC:add] synonym: "lymphocytic blood cell differentiation" EXACT [] is_a: GO:0046649 ! lymphocyte activation is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000542 ! lymphocyte relationship: results_in_acquisition_of_features_of CL:0000542 ! lymphocyte [Term] id: GO:0030099 name: myeloid cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." [GOC:add, ISBN:0781735149] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000763 ! myeloid cell relationship: part_of GO:0030097 ! hemopoiesis relationship: results_in_acquisition_of_features_of CL:0000763 ! myeloid cell [Term] id: GO:0030133 name: transport vesicle namespace: cellular_component def: "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." [GOC:mah, PMID:22160157] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'. synonym: "constitutive secretory pathway transport vesicle" EXACT [] synonym: "Golgi to vacuole transport vesicle" NARROW [] synonym: "Golgi-vacuole transport vesicle" NARROW [] synonym: "secretory vesicle" RELATED [] xref: NIF_Subcellular:sao885490876 is_a: GO:0031410 ! cytoplasmic vesicle relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0030141 name: secretory granule namespace: cellular_component def: "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." [GOC:mah, ISBN:0198506732] comment: Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'. synonym: "secretory vesicle" BROAD [] is_a: GO:0099503 ! secretory vesicle relationship: part_of GO:0012505 ! endomembrane system property_value: RO:0002161 NCBITaxon:4890 [Term] id: GO:0030154 name: cell differentiation namespace: biological_process def: "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." [ISBN:0198506732] subset: goslim_agr subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_mouse subset: goslim_plant xref: Wikipedia:Cellular_differentiation is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0048869 ! cellular developmental process intersection_of: results_in_acquisition_of_features_of CL:0000000 ! cell relationship: results_in_acquisition_of_features_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0030155 name: regulation of cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." [GOC:mah] synonym: "cell adhesion receptor regulator activity" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007155 ! cell adhesion relationship: regulates GO:0007155 ! cell adhesion [Term] id: GO:0030163 name: protein catabolic process namespace: biological_process alt_id: GO:0044254 alt_id: GO:0044257 def: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah] comment: This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children. subset: goslim_candida subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: prokaryote_subset synonym: "cellular protein breakdown" EXACT [] synonym: "cellular protein catabolic process" EXACT [] synonym: "cellular protein catabolism" EXACT [] synonym: "cellular protein degradation" EXACT [] synonym: "multicellular organismal protein catabolic process" NARROW [] synonym: "pheromone catabolic process" RELATED [] synonym: "pheromone catabolism" RELATED [] synonym: "protein breakdown" EXACT [] synonym: "protein catabolism" EXACT [] synonym: "protein degradation" EXACT [] xref: Wikipedia:Protein_catabolism is_a: GO:0009057 ! macromolecule catabolic process is_a: GO:0019538 ! protein metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0030182 name: neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron." [GOC:mah] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000540 ! neuron relationship: part_of GO:0048699 ! generation of neurons relationship: results_in_acquisition_of_features_of CL:0000540 ! neuron [Term] id: GO:0030198 name: extracellular matrix organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." [GOC:mah] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic synonym: "extracellular matrix organisation" EXACT [] synonym: "extracellular matrix organization and biogenesis" RELATED [GOC:mah] is_a: GO:0043062 ! extracellular structure organization is_a: GO:0045229 ! external encapsulating structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031012 ! extracellular matrix relationship: results_in_organization_of GO:0031012 ! extracellular matrix [Term] id: GO:0030199 name: collagen fibril organization namespace: biological_process def: "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." [GOC:mah, ISBN:0815316194] synonym: "collagen fibril organisation" EXACT [] synonym: "fibrillar collagen organization" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0098643 ! banded collagen fibril relationship: results_in_organization_of GO:0098643 ! banded collagen fibril property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0030203 name: glycosaminoglycan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." [ISBN:0192800981] synonym: "glycosaminoglycan metabolism" EXACT [] is_a: GO:0006022 ! aminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan relationship: has_primary_input_or_output CHEBI:18085 ! glycosaminoglycan [Term] id: GO:0030212 name: hyaluronan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan metabolism" EXACT [] is_a: GO:1903510 ! mucopolysaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid relationship: has_primary_input_or_output CHEBI:16336 ! hyaluronic acid [Term] id: GO:0030213 name: hyaluronan biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan anabolism" EXACT [] synonym: "hyaluronan biosynthesis" EXACT [] synonym: "hyaluronan formation" EXACT [] synonym: "hyaluronan synthesis" EXACT [] is_a: GO:0006024 ! glycosaminoglycan biosynthetic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16336 ! hyaluronic acid relationship: has_primary_output CHEBI:16336 ! hyaluronic acid [Term] id: GO:0030214 name: hyaluronan catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." [GOC:mah, ISBN:0198506732] synonym: "hyaluronan breakdown" EXACT [] synonym: "hyaluronan catabolism" EXACT [] synonym: "hyaluronan degradation" EXACT [] is_a: GO:0006027 ! glycosaminoglycan catabolic process is_a: GO:0030212 ! hyaluronan metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16336 ! hyaluronic acid relationship: has_primary_input CHEBI:16336 ! hyaluronic acid [Term] id: GO:0030217 name: T cell differentiation namespace: biological_process alt_id: GO:0042112 alt_id: GO:0046652 def: "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." [GO_REF:0000022, GOC:jid, GOC:mah] comment: Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "T cell development" RELATED [GOC:add] synonym: "T lymphocyte differentiation" EXACT [] synonym: "T-cell differentiation" EXACT [] synonym: "T-lymphocyte differentiation" EXACT [] is_a: GO:0030098 ! lymphocyte differentiation is_a: GO:0042110 ! T cell activation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000084 ! T cell relationship: results_in_acquisition_of_features_of CL:0000084 ! T cell [Term] id: GO:0030218 name: erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." [GOC:mah] synonym: "erythrocyte cell differentiation" EXACT [] synonym: "erythropoiesis" EXACT [GOC:add, GOC:dph] synonym: "RBC differentiation" EXACT [CL:0000232] synonym: "red blood cell differentiation" EXACT [CL:0000232] xref: Wikipedia:Erythropoiesis is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000232 ! erythrocyte relationship: part_of GO:0034101 ! erythrocyte homeostasis relationship: results_in_acquisition_of_features_of CL:0000232 ! erythrocyte [Term] id: GO:0030219 name: megakaryocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." [GOC:mah] synonym: "megakaryocyte cell differentiation" EXACT [] is_a: GO:0030099 ! myeloid cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000556 ! megakaryocyte relationship: results_in_acquisition_of_features_of CL:0000556 ! megakaryocyte [Term] id: GO:0030239 name: myofibril assembly namespace: biological_process def: "Formation of myofibrils, the repeating units of striated muscle." [GOC:mah] is_a: GO:0010927 ! cellular component assembly involved in morphogenesis is_a: GO:0031032 ! actomyosin structure organization is_a: GO:0097435 ! supramolecular fiber organization is_a: GO:0140694 ! non-membrane-bounded organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0030016 ! myofibril relationship: part_of GO:0055002 ! striated muscle cell development relationship: results_in_assembly_of GO:0030016 ! myofibril [Term] id: GO:0030261 name: chromosome condensation namespace: biological_process alt_id: GO:0000068 def: "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:mah, ISBN:0815316194] synonym: "DNA condensation" BROAD [Wikipedia:DNA_condensation] synonym: "eukaryotic chromosome condensation" EXACT [GOC:bf] synonym: "nuclear chromosome condensation" EXACT [GOC:bf] is_a: GO:0051276 ! chromosome organization [Term] id: GO:0030262 name: apoptotic nuclear changes namespace: biological_process def: "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." [GOC:mah, GOC:mtg_apoptosis] synonym: "apoptotic nuclear change" NARROW [] is_a: GO:0006921 ! cellular component disassembly involved in execution phase of apoptosis [Term] id: GO:0030263 name: apoptotic chromosome condensation namespace: biological_process def: "The compaction of chromatin during apoptosis." [GOC:mah] synonym: "pyknosis" EXACT [] xref: Wikipedia:Pyknosis is_a: GO:0030261 ! chromosome condensation relationship: part_of GO:0030262 ! apoptotic nuclear changes [Term] id: GO:0030264 name: nuclear fragmentation involved in apoptotic nuclear change namespace: biological_process def: "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." [GOC:dph, GOC:mah, GOC:mtg_apoptosis, GOC:tb, ISBN:0721639976] synonym: "apoptotic nuclear fragmentation" EXACT [] synonym: "nuclear fragmentation during apoptosis" RELATED [GOC:dph, GOC:tb] synonym: "nucleus fragmentation" EXACT [] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: part_of GO:0030262 ! apoptotic nuclear changes relationship: part_of GO:0030262 ! apoptotic nuclear changes [Term] id: GO:0030278 name: regulation of ossification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "regulation of bone biosynthesis" EXACT [] synonym: "regulation of bone formation" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001503 ! ossification relationship: regulates GO:0001503 ! ossification [Term] id: GO:0030279 name: negative regulation of ossification namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "down regulation of ossification" EXACT [] synonym: "down-regulation of ossification" EXACT [] synonym: "downregulation of ossification" EXACT [] synonym: "inhibition of ossification" NARROW [] synonym: "negative regulation of bone biosynthesis" EXACT [] synonym: "negative regulation of bone formation" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001503 ! ossification relationship: negatively_regulates GO:0001503 ! ossification [Term] id: GO:0030307 name: positive regulation of cell growth namespace: biological_process def: "Any process that activates or increases the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "activation of cell growth" NARROW [] synonym: "stimulation of cell growth" NARROW [] synonym: "up regulation of cell growth" EXACT [] synonym: "up-regulation of cell growth" EXACT [] synonym: "upregulation of cell growth" EXACT [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016049 ! cell growth relationship: positively_regulates GO:0016049 ! cell growth [Term] id: GO:0030308 name: negative regulation of cell growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." [GOC:go_curators] synonym: "down regulation of cell growth" EXACT [] synonym: "down-regulation of cell growth" EXACT [] synonym: "downregulation of cell growth" EXACT [] synonym: "inhibition of cell growth" NARROW [] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016049 ! cell growth relationship: negatively_regulates GO:0016049 ! cell growth [Term] id: GO:0030312 name: external encapsulating structure namespace: cellular_component def: "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." [GOC:go_curators] comment: The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_plant is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell relationship: part_of GO:0071944 ! cell periphery [Term] id: GO:0030317 name: flagellated sperm motility namespace: biological_process alt_id: GO:0097724 alt_id: GO:1905419 def: "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm." [GO_REF:0000060, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:26680031] synonym: "flagellated sperm movement" EXACT [] synonym: "sperm flagellum movement" EXACT [GOC:cilia, GOC:krc] synonym: "sperm flagellum movement involved in flagellated sperm motility" EXACT [] synonym: "sperm flagellum movement involved in flagellated sperm movement" EXACT [GOC:TermGenie] synonym: "sperm motility" BROAD [] synonym: "sperm movement" BROAD [] xref: Wikipedia:Sperm_motility is_a: GO:0060285 ! cilium-dependent cell motility is_a: GO:0060294 ! cilium movement involved in cell motility is_a: GO:0097722 ! sperm motility intersection_of: GO:0060285 ! cilium-dependent cell motility intersection_of: results_in_movement_of CL:0000019 ! sperm [Term] id: GO:0030323 name: respiratory tube development namespace: biological_process def: "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." [GOC:jid] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000117 ! respiratory tube relationship: results_in_development_of UBERON:0000117 ! respiratory tube [Term] id: GO:0030324 name: lung development namespace: biological_process def: "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:jid, UBERON:0002048] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002048 ! lung relationship: part_of GO:0030323 ! respiratory tube development relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0002048 ! lung [Term] id: GO:0030334 name: regulation of cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell migration." [GOC:go_curators] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016477 ! cell migration relationship: regulates GO:0016477 ! cell migration [Term] id: GO:0030335 name: positive regulation of cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "activation of cell migration" NARROW [] synonym: "stimulation of cell migration" NARROW [] synonym: "up regulation of cell migration" EXACT [] synonym: "up-regulation of cell migration" EXACT [] synonym: "upregulation of cell migration" EXACT [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016477 ! cell migration relationship: positively_regulates GO:0016477 ! cell migration [Term] id: GO:0030336 name: negative regulation of cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." [GOC:go_curators] synonym: "down regulation of cell migration" EXACT [] synonym: "down-regulation of cell migration" EXACT [] synonym: "downregulation of cell migration" EXACT [] synonym: "inhibition of cell migration" NARROW [] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016477 ! cell migration relationship: negatively_regulates GO:0016477 ! cell migration [Term] id: GO:0030397 name: membrane disassembly namespace: biological_process def: "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." [GOC:mah] synonym: "membrane breakdown" EXACT [] synonym: "membrane catabolism" EXACT [] synonym: "membrane degradation" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0016020 ! membrane relationship: results_in_disassembly_of GO:0016020 ! membrane [Term] id: GO:0030421 name: defecation namespace: biological_process def: "The expulsion of feces from the rectum." [GOC:mah] xref: Wikipedia:Defecation is_a: GO:0007588 ! excretion is_a: GO:0022600 ! digestive system process [Term] id: GO:0030424 name: axon namespace: cellular_component def: "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." [GOC:nln, ISBN:0198506732] xref: NIF_Subcellular:sao1770195789 xref: Wikipedia:Axon is_a: GO:0043005 ! neuron projection [Term] id: GO:0030432 name: peristalsis namespace: biological_process def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards." [ISBN:0198506732] xref: Wikipedia:Peristalsis is_a: GO:0014821 ! phasic smooth muscle contraction [Term] id: GO:0030473 name: nuclear migration along microtubule namespace: biological_process alt_id: GO:0000065 def: "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." [GOC:mah, GOC:sgd_curators] synonym: "microtubule cytoskeleton-dependent nuclear positioning" EXACT [] synonym: "microtubule cytoskeleton-dependent nucleus positioning" EXACT [] synonym: "microtubule-dependent nuclear positioning" EXACT [] synonym: "microtubule-dependent nucleus positioning" EXACT [] synonym: "microtubule-mediated nuclear migration" EXACT [] synonym: "nuclear migration, microtubule-mediated" EXACT [] synonym: "nuclear movement, microtubule-mediated" BROAD [] synonym: "nucleus migration" BROAD [] synonym: "transport of nucleus by microtubules" EXACT [] synonym: "transport of nucleus, microtubule-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0072384 ! organelle transport along microtubule intersection_of: GO:0007097 ! nuclear migration intersection_of: results_in_transport_along GO:0015630 ! microtubule cytoskeleton relationship: results_in_transport_along GO:0015630 ! microtubule cytoskeleton [Term] id: GO:0030485 name: smooth muscle contractile fiber namespace: cellular_component def: "The contractile fiber of smooth muscle cells." [GOC:mah] is_a: GO:0043292 ! contractile fiber intersection_of: GO:0043292 ! contractile fiber intersection_of: part_of CL:0000192 ! smooth muscle cell relationship: part_of CL:0000192 ! smooth muscle cell [Term] id: GO:0030539 name: male genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure." [GOC:ems, ISBN:0140512888] synonym: "male genital development" EXACT [] is_a: GO:0048806 ! genitalia development is_a: GO:0061458 ! reproductive system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000079 ! male reproductive system relationship: part_of GO:0046661 ! male sex differentiation relationship: results_in_development_of UBERON:0000079 ! male reproductive system [Term] id: GO:0030573 name: bile acid catabolic process namespace: biological_process alt_id: GO:0019613 def: "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile." [GOC:go_curators] synonym: "bile acid 7alpha-dehydroxylation pathway" NARROW [] synonym: "bile acid breakdown" EXACT [] synonym: "bile acid catabolism" EXACT [] synonym: "bile acid degradation" EXACT [] synonym: "cholate catabolic process" NARROW [] xref: MetaCyc:7ALPHADEHYDROX-PWY is_a: GO:0008206 ! bile acid metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36235 ! bile acid anion relationship: has_primary_input CHEBI:36235 ! bile acid anion [Term] id: GO:0030574 name: collagen catabolic process namespace: biological_process def: "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." [GOC:mah, ISBN:0815316194] synonym: "collagen breakdown" EXACT [] synonym: "collagen catabolism" EXACT [] synonym: "collagen degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input GO:0005581 ! collagen trimer relationship: has_primary_input GO:0005581 ! collagen trimer [Term] id: GO:0030658 name: transport vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a transport vesicle." [GOC:mah] synonym: "constitutive secretory pathway transport vesicle membrane" EXACT [] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0030133 ! transport vesicle relationship: bounding_layer_of GO:0030133 ! transport vesicle relationship: part_of GO:0030133 ! transport vesicle [Term] id: GO:0030659 name: cytoplasmic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a cytoplasmic vesicle." [GOC:mah] is_a: GO:0012506 ! vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0031410 ! cytoplasmic vesicle relationship: part_of GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0030660 name: Golgi-associated vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." [GOC:mah] synonym: "Golgi vesicle membrane" RELATED [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005798 ! Golgi-associated vesicle relationship: bounding_layer_of GO:0005798 ! Golgi-associated vesicle relationship: part_of GO:0005798 ! Golgi-associated vesicle [Term] id: GO:0030667 name: secretory granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a secretory granule." [GOC:mah] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0030141 ! secretory granule relationship: bounding_layer_of GO:0030141 ! secretory granule relationship: part_of GO:0030141 ! secretory granule [Term] id: GO:0030705 name: cytoskeleton-dependent intracellular transport namespace: biological_process def: "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." [GOC:mah] subset: goslim_chembl subset: goslim_drosophila is_a: GO:0046907 ! intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber relationship: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber [Term] id: GO:0030718 name: germ-line stem cell population maintenance namespace: biological_process def: "Any process by which an organism or tissue maintains a population of germ-line stem cells." [ISBN:0879694238] is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000014 ! germ line stem cell relationship: acts_on_population_of CL:0000014 ! germ line stem cell [Term] id: GO:0030720 name: oocyte localization involved in germarium-derived egg chamber formation namespace: biological_process def: "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." [GOC:mtg_sensu, PMID:10449356] synonym: "establishment and maintenance of oocyte localization in egg chamber" EXACT [] synonym: "establishment and maintenance of oocyte position during oogenesis" EXACT [] synonym: "oocyte localisation involved in germarium-derived egg chamber formation" EXACT [GOC:mah] synonym: "oocyte localization during germarium-derived egg chamber formation" RELATED [GOC:dph, GOC:tb] synonym: "oocyte localization during oogenesis" RELATED [] synonym: "oocyte positioning during oogenesis" NARROW [] synonym: "oogenesis, establishment and maintenance of oocyte localization" EXACT [] synonym: "oogenesis, oocyte localization" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051674 ! localization of cell intersection_of: GO:0051179 ! localization intersection_of: has_primary_input CL:0000023 ! oocyte relationship: has_primary_input CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:50557 {all_only="true"} ! Insecta relationship: only_in_taxon NCBITaxon:50557 ! Insecta relationship: part_of GO:0007293 ! germarium-derived egg chamber formation [Term] id: GO:0030855 name: epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." [GOC:ecd, PMID:11839751] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell relationship: part_of GO:0060429 ! epithelium development relationship: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell [Term] id: GO:0030856 name: regulation of epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030855 ! epithelial cell differentiation relationship: regulates GO:0030855 ! epithelial cell differentiation [Term] id: GO:0030857 name: negative regulation of epithelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "down regulation of epithelial cell differentiation" EXACT [] synonym: "down-regulation of epithelial cell differentiation" EXACT [] synonym: "downregulation of epithelial cell differentiation" EXACT [] synonym: "inhibition of epithelial cell differentiation" NARROW [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030855 ! epithelial cell differentiation relationship: negatively_regulates GO:0030855 ! epithelial cell differentiation [Term] id: GO:0030858 name: positive regulation of epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." [GOC:mah] synonym: "activation of epithelial cell differentiation" NARROW [] synonym: "stimulation of epithelial cell differentiation" NARROW [] synonym: "up regulation of epithelial cell differentiation" EXACT [] synonym: "up-regulation of epithelial cell differentiation" EXACT [] synonym: "upregulation of epithelial cell differentiation" EXACT [] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045597 ! positive regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030855 ! epithelial cell differentiation relationship: positively_regulates GO:0030855 ! epithelial cell differentiation [Term] id: GO:0030900 name: forebrain development namespace: biological_process def: "The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain] synonym: "prosencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001890 ! forebrain relationship: part_of GO:0007420 ! brain development relationship: results_in_development_of UBERON:0001890 ! forebrain [Term] id: GO:0030901 name: midbrain development namespace: biological_process def: "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain] synonym: "mesencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001891 ! midbrain relationship: part_of GO:0007420 ! brain development relationship: results_in_development_of UBERON:0001891 ! midbrain [Term] id: GO:0030902 name: hindbrain development namespace: biological_process def: "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." [http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain] synonym: "rhombencephalon development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002028 ! hindbrain relationship: part_of GO:0007420 ! brain development relationship: results_in_development_of UBERON:0002028 ! hindbrain [Term] id: GO:0030903 name: notochord development namespace: biological_process def: "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:dgh] is_a: GO:0048568 ! embryonic organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002328 ! notochord relationship: results_in_development_of UBERON:0002328 ! notochord [Term] id: GO:0030910 name: olfactory placode formation namespace: biological_process def: "The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:dgh] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003050 ! olfactory placode relationship: part_of GO:0043584 ! nose development relationship: part_of GO:0071699 ! olfactory placode morphogenesis relationship: results_in_formation_of UBERON:0003050 ! olfactory placode [Term] id: GO:0030916 name: otic vesicle formation namespace: biological_process def: "The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:dgh] synonym: "otocyst biosynthesis" EXACT [] synonym: "otocyst formation" EXACT [] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003051 ! ear vesicle relationship: part_of GO:0071600 ! otic vesicle morphogenesis relationship: results_in_formation_of UBERON:0003051 ! ear vesicle [Term] id: GO:0030917 name: midbrain-hindbrain boundary development namespace: biological_process def: "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." [GOC:dgh] synonym: "isthmic organizer development" EXACT [] synonym: "isthmomesencephalic boundary development" EXACT [] synonym: "isthmus development" EXACT [] synonym: "MHB development" EXACT [] synonym: "midbrain-hindbrain orgainizer development" EXACT [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of GO:0007420 ! brain development relationship: part_of GO:0021903 ! rostrocaudal neural tube patterning relationship: results_in_development_of UBERON:0003052 ! midbrain-hindbrain boundary [Term] id: GO:0030936 name: transmembrane collagen trimer namespace: cellular_component def: "Any collagen trimer that passes through a lipid bilayer membrane." [ISBN:0721639976] synonym: "MACIT" EXACT [ISBN:0198599587] is_a: GO:0005581 ! collagen trimer is_a: GO:0098797 ! plasma membrane protein complex intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0005886 ! plasma membrane [Term] id: GO:0030951 name: establishment or maintenance of microtubule cytoskeleton polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." [GOC:mah] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0030952 ! establishment or maintenance of cytoskeleton polarity [Term] id: GO:0030952 name: establishment or maintenance of cytoskeleton polarity namespace: biological_process def: "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." [GOC:mah] synonym: "cytoskeleton polarization" RELATED [] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0030990 name: intraciliary transport particle namespace: cellular_component def: "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." [GOC:cilia, GOC:kmv, PMID:14570576, PMID:22118932, PMID:23945166] comment: Note that we deem cilia and microtubule-based flagella to be equivalent. subset: goslim_pir synonym: "IFT complex" RELATED [] synonym: "intraflagellar transport complex" EXACT [] synonym: "intraflagellar transport particle" EXACT [] is_a: GO:0032991 ! protein-containing complex relationship: capable_of_part_of GO:0035735 ! intraciliary transport involved in cilium assembly [Term] id: GO:0031012 name: extracellular matrix namespace: cellular_component alt_id: GO:0005578 def: "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." [GOC:BHF, GOC:mah, GOC:rph, NIF_Subcellular:nlx_subcell_20090513, PMID:21123617, PMID:28089324] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: prokaryote_subset synonym: "matrisome" NARROW [] synonym: "proteinaceous extracellular matrix" EXACT [] xref: NIF_Subcellular:nlx_subcell_20090513 xref: Wikipedia:Extracellular_matrix is_a: GO:0030312 ! external encapsulating structure disjoint_from: GO:0032991 ! protein-containing complex disjoint_from: GO:0043226 ! organelle [Term] id: GO:0031016 name: pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones." [GOC:cvs] xref: Wikipedia:Pancreas is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001264 ! pancreas relationship: results_in_development_of UBERON:0001264 ! pancreas property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23777" xsd:anyURI [Term] id: GO:0031017 name: exocrine pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells." [GOC:cvs] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000017 ! exocrine pancreas relationship: part_of GO:0031016 ! pancreas development relationship: part_of GO:0035272 ! exocrine system development relationship: part_of GO:0055123 ! digestive system development relationship: results_in_development_of UBERON:0000017 ! exocrine pancreas [Term] id: GO:0031018 name: endocrine pancreas development namespace: biological_process def: "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin." [GOC:cvs] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000016 ! endocrine pancreas relationship: part_of GO:0031016 ! pancreas development relationship: part_of GO:0035270 ! endocrine system development relationship: results_in_development_of UBERON:0000016 ! endocrine pancreas [Term] id: GO:0031022 name: nuclear migration along microfilament namespace: biological_process def: "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." [GOC:mah] synonym: "nuclear migration, microfilament-mediated" EXACT [] is_a: GO:0007097 ! nuclear migration is_a: GO:0030048 ! actin filament-based movement is_a: GO:0099515 ! actin filament-based transport intersection_of: GO:0007097 ! nuclear migration intersection_of: results_in_transport_along GO:0005884 ! actin filament [Term] id: GO:0031032 name: actomyosin structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." [GOC:dph, GOC:jl, GOC:mah] comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins. synonym: "actomyosin organization" EXACT [] synonym: "actomyosin structure organisation" EXACT [] synonym: "actomyosin structure organization and biogenesis" RELATED [GOC:mah] is_a: GO:0030036 ! actin cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0042641 ! actomyosin relationship: results_in_organization_of GO:0042641 ! actomyosin [Term] id: GO:0031076 name: embryonic camera-type eye development namespace: biological_process def: "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." [GOC:mah, GOC:mtg_sensu] synonym: "embryonic eye development" EXACT [] is_a: GO:0043010 ! camera-type eye development is_a: GO:0048568 ! embryonic organ development [Term] id: GO:0031090 name: organelle membrane namespace: cellular_component def: "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." [GOC:dos, GOC:mah] synonym: "intracellular membrane" RELATED [NIF_Subcellular:sao830981606] xref: NIF_Subcellular:sao830981606 is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031109 name: microtubule polymerization or depolymerization namespace: biological_process def: "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] synonym: "microtubule dynamics" EXACT [] is_a: GO:0000226 ! microtubule cytoskeleton organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23195" xsd:anyURI [Term] id: GO:0031110 name: regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." [GOC:mah] is_a: GO:0070507 ! regulation of microtubule cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031109 ! microtubule polymerization or depolymerization relationship: regulates GO:0031109 ! microtubule polymerization or depolymerization [Term] id: GO:0031111 name: negative regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "down-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "downregulation of microtubule polymerization or depolymerization" EXACT [] synonym: "inhibition of microtubule polymerization or depolymerization" NARROW [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051494 ! negative regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization relationship: negatively_regulates GO:0031109 ! microtubule polymerization or depolymerization [Term] id: GO:0031112 name: positive regulation of microtubule polymerization or depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." [GOC:mah] synonym: "activation of microtubule polymerization or depolymerization" NARROW [] synonym: "stimulation of microtubule polymerization or depolymerization" NARROW [] synonym: "up regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "up-regulation of microtubule polymerization or depolymerization" EXACT [] synonym: "upregulation of microtubule polymerization or depolymerization" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0051495 ! positive regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization relationship: positively_regulates GO:0031109 ! microtubule polymerization or depolymerization [Term] id: GO:0031113 name: regulation of microtubule polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule polymerization." [GOC:mah] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:0032271 ! regulation of protein polymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046785 ! microtubule polymerization relationship: regulates GO:0046785 ! microtubule polymerization [Term] id: GO:0031114 name: regulation of microtubule depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "regulation of microtubule disassembly" EXACT [] is_a: GO:0031110 ! regulation of microtubule polymerization or depolymerization is_a: GO:1901879 ! regulation of protein depolymerization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007019 ! microtubule depolymerization relationship: regulates GO:0007019 ! microtubule depolymerization [Term] id: GO:0031115 name: negative regulation of microtubule polymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "down regulation of microtubule polymerization" EXACT [] synonym: "down-regulation of microtubule polymerization" EXACT [] synonym: "downregulation of microtubule polymerization" EXACT [] synonym: "inhibition of microtubule polymerization" NARROW [] is_a: GO:0031111 ! negative regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032272 ! negative regulation of protein polymerization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046785 ! microtubule polymerization relationship: negatively_regulates GO:0046785 ! microtubule polymerization [Term] id: GO:0031116 name: positive regulation of microtubule polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." [GOC:mah] synonym: "activation of microtubule polymerization" NARROW [] synonym: "stimulation of microtubule polymerization" NARROW [] synonym: "up regulation of microtubule polymerization" EXACT [] synonym: "up-regulation of microtubule polymerization" EXACT [] synonym: "upregulation of microtubule polymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031113 ! regulation of microtubule polymerization is_a: GO:0032273 ! positive regulation of protein polymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046785 ! microtubule polymerization relationship: positively_regulates GO:0046785 ! microtubule polymerization [Term] id: GO:0031117 name: positive regulation of microtubule depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." [GOC:mah] synonym: "activation of microtubule depolymerization" NARROW [] synonym: "microtubule destabilization" EXACT [] synonym: "positive regulation of microtubule catastrophe" NARROW [GOC:dph, GOC:tb] synonym: "positive regulation of microtubule disassembly" EXACT [] synonym: "stimulation of microtubule depolymerization" NARROW [] synonym: "up regulation of microtubule depolymerization" EXACT [] synonym: "up-regulation of microtubule depolymerization" EXACT [] synonym: "upregulation of microtubule depolymerization" EXACT [] is_a: GO:0031112 ! positive regulation of microtubule polymerization or depolymerization is_a: GO:0031114 ! regulation of microtubule depolymerization is_a: GO:1901881 ! positive regulation of protein depolymerization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007019 ! microtubule depolymerization relationship: positively_regulates GO:0007019 ! microtubule depolymerization [Term] id: GO:0031122 name: cytoplasmic microtubule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." [GOC:mah] synonym: "cytoplasmic microtubule organisation" EXACT [] synonym: "cytoplasmic microtubule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005881 ! cytoplasmic microtubule relationship: results_in_organization_of GO:0005881 ! cytoplasmic microtubule [Term] id: GO:0031128 name: developmental induction namespace: biological_process def: "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." [GOC:cjm, GOC:dph, GOC:mah, PMID:24503535] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment relationship: has_part GO:0045168 ! cell-cell signaling involved in cell fate commitment property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0031175 name: neuron projection development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." [GOC:mah] synonym: "neurite biosynthesis" NARROW [] synonym: "neurite development" NARROW [GOC:dph] synonym: "neurite formation" NARROW [] synonym: "neurite growth" NARROW [] synonym: "neurite outgrowth" NARROW [] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: part_of GO:0048666 ! neuron development relationship: part_of GO:0048666 ! neuron development [Term] id: GO:0031252 name: cell leading edge namespace: cellular_component def: "The area of a motile cell closest to the direction of movement." [GOC:pg] subset: goslim_pir synonym: "front of cell" EXACT [] synonym: "leading edge of cell" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell [Term] id: GO:0031253 name: cell projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." [GOC:krc, GOC:mah] synonym: "membrane extension" RELATED [] synonym: "membrane projection" RELATED [] is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection relationship: bounding_layer_of GO:0120025 ! plasma membrane bounded cell projection relationship: part_of GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0031256 name: leading edge membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding the leading edge of a motile cell." [GOC:mah] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0031252 ! cell leading edge [Term] id: GO:0031323 name: regulation of cellular metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gocheck_do_not_annotate synonym: "regulation of cellular metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044237 ! cellular metabolic process relationship: regulates GO:0044237 ! cellular metabolic process [Term] id: GO:0031324 name: negative regulation of cellular metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gocheck_do_not_annotate synonym: "down regulation of cellular metabolic process" EXACT [] synonym: "down-regulation of cellular metabolic process" EXACT [] synonym: "downregulation of cellular metabolic process" EXACT [] synonym: "inhibition of cellular metabolic process" NARROW [] synonym: "negative regulation of cellular metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044237 ! cellular metabolic process relationship: negatively_regulates GO:0044237 ! cellular metabolic process [Term] id: GO:0031325 name: positive regulation of cellular metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." [GOC:mah] subset: gocheck_do_not_annotate synonym: "activation of cellular metabolic process" NARROW [] synonym: "positive regulation of cellular metabolism" EXACT [] synonym: "stimulation of cellular metabolic process" NARROW [] synonym: "up regulation of cellular metabolic process" EXACT [] synonym: "up-regulation of cellular metabolic process" EXACT [] synonym: "upregulation of cellular metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044237 ! cellular metabolic process relationship: positively_regulates GO:0044237 ! cellular metabolic process [Term] id: GO:0031326 name: regulation of cellular biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "regulation of cellular anabolism" EXACT [] synonym: "regulation of cellular biosynthesis" EXACT [] synonym: "regulation of cellular formation" EXACT [] synonym: "regulation of cellular synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044249 ! cellular biosynthetic process relationship: regulates GO:0044249 ! cellular biosynthetic process [Term] id: GO:0031327 name: negative regulation of cellular biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "down regulation of cellular biosynthetic process" EXACT [] synonym: "down-regulation of cellular biosynthetic process" EXACT [] synonym: "downregulation of cellular biosynthetic process" EXACT [] synonym: "inhibition of cellular biosynthetic process" NARROW [] synonym: "negative regulation of cellular anabolism" EXACT [] synonym: "negative regulation of cellular biosynthesis" EXACT [] synonym: "negative regulation of cellular formation" EXACT [] synonym: "negative regulation of cellular synthesis" EXACT [] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044249 ! cellular biosynthetic process relationship: negatively_regulates GO:0044249 ! cellular biosynthetic process [Term] id: GO:0031328 name: positive regulation of cellular biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:mah] synonym: "activation of cellular biosynthetic process" NARROW [] synonym: "positive regulation of cellular anabolism" EXACT [] synonym: "positive regulation of cellular biosynthesis" EXACT [] synonym: "positive regulation of cellular formation" EXACT [] synonym: "positive regulation of cellular synthesis" EXACT [] synonym: "stimulation of cellular biosynthetic process" NARROW [] synonym: "up regulation of cellular biosynthetic process" EXACT [] synonym: "up-regulation of cellular biosynthetic process" EXACT [] synonym: "upregulation of cellular biosynthetic process" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044249 ! cellular biosynthetic process relationship: positively_regulates GO:0044249 ! cellular biosynthetic process [Term] id: GO:0031329 name: regulation of cellular catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "regulation of cellular breakdown" EXACT [] synonym: "regulation of cellular catabolism" EXACT [] synonym: "regulation of cellular degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044248 ! cellular catabolic process relationship: regulates GO:0044248 ! cellular catabolic process [Term] id: GO:0031330 name: negative regulation of cellular catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "down regulation of cellular catabolic process" EXACT [] synonym: "down-regulation of cellular catabolic process" EXACT [] synonym: "downregulation of cellular catabolic process" EXACT [] synonym: "inhibition of cellular catabolic process" NARROW [] synonym: "negative regulation of cellular breakdown" EXACT [] synonym: "negative regulation of cellular catabolism" EXACT [] synonym: "negative regulation of cellular degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044248 ! cellular catabolic process relationship: negatively_regulates GO:0044248 ! cellular catabolic process [Term] id: GO:0031331 name: positive regulation of cellular catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:mah] synonym: "activation of cellular catabolic process" NARROW [] synonym: "positive regulation of cellular breakdown" EXACT [] synonym: "positive regulation of cellular catabolism" EXACT [] synonym: "positive regulation of cellular degradation" EXACT [] synonym: "stimulation of cellular catabolic process" NARROW [] synonym: "up regulation of cellular catabolic process" EXACT [] synonym: "up-regulation of cellular catabolic process" EXACT [] synonym: "upregulation of cellular catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044248 ! cellular catabolic process relationship: positively_regulates GO:0044248 ! cellular catabolic process [Term] id: GO:0031333 name: negative regulation of protein-containing complex assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "down regulation of protein complex assembly" EXACT [] synonym: "down-regulation of protein complex assembly" EXACT [] synonym: "downregulation of protein complex assembly" EXACT [] synonym: "inhibition of protein complex assembly" NARROW [] synonym: "negative regulation of protein complex assembly" RELATED [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0065003 ! protein-containing complex assembly relationship: negatively_regulates GO:0065003 ! protein-containing complex assembly [Term] id: GO:0031334 name: positive regulation of protein-containing complex assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex assembly." [GOC:mah] synonym: "activation of protein complex assembly" NARROW [] synonym: "positive regulation of protein complex assembly" RELATED [] synonym: "stimulation of protein complex assembly" NARROW [] synonym: "up regulation of protein complex assembly" EXACT [] synonym: "up-regulation of protein complex assembly" EXACT [] synonym: "upregulation of protein complex assembly" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0065003 ! protein-containing complex assembly relationship: positively_regulates GO:0065003 ! protein-containing complex assembly [Term] id: GO:0031338 name: regulation of vesicle fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle fusion." [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0060627 ! regulation of vesicle-mediated transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006906 ! vesicle fusion relationship: regulates GO:0006906 ! vesicle fusion [Term] id: GO:0031339 name: negative regulation of vesicle fusion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "down regulation of vesicle fusion" EXACT [] synonym: "down-regulation of vesicle fusion" EXACT [] synonym: "downregulation of vesicle fusion" EXACT [] synonym: "inhibition of vesicle fusion" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006906 ! vesicle fusion relationship: negatively_regulates GO:0006906 ! vesicle fusion [Term] id: GO:0031340 name: positive regulation of vesicle fusion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion." [GOC:mah] synonym: "activation of vesicle fusion" NARROW [] synonym: "stimulation of vesicle fusion" NARROW [] synonym: "up regulation of vesicle fusion" EXACT [] synonym: "up-regulation of vesicle fusion" EXACT [] synonym: "upregulation of vesicle fusion" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006906 ! vesicle fusion relationship: positively_regulates GO:0006906 ! vesicle fusion [Term] id: GO:0031344 name: regulation of cell projection organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "regulation of cell projection organisation" EXACT [] synonym: "regulation of cell projection organization and biogenesis" RELATED [GOC:mah] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030030 ! cell projection organization relationship: regulates GO:0030030 ! cell projection organization [Term] id: GO:0031345 name: negative regulation of cell projection organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "down regulation of cell projection organization" EXACT [GOC:mah] synonym: "down-regulation of cell projection organization" EXACT [] synonym: "downregulation of cell projection organization" EXACT [] synonym: "inhibition of cell projection organization" NARROW [] synonym: "negative regulation of cell projection organisation" EXACT [] synonym: "negative regulation of cell projection organization and biogenesis" RELATED [GOC:mah] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030030 ! cell projection organization relationship: negatively_regulates GO:0030030 ! cell projection organization [Term] id: GO:0031346 name: positive regulation of cell projection organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." [GOC:mah] synonym: "activation of cell projection organization" NARROW [] synonym: "positive regulation of cell projection organisation" EXACT [] synonym: "positive regulation of cell projection organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cell projection organization" NARROW [] synonym: "up regulation of cell projection organization" EXACT [] synonym: "up-regulation of cell projection organization" EXACT [] synonym: "upregulation of cell projection organization" EXACT [] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030030 ! cell projection organization relationship: positively_regulates GO:0030030 ! cell projection organization [Term] id: GO:0031347 name: regulation of defense response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a defense response." [GOC:mah] is_a: GO:0080134 ! regulation of response to stress intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006952 ! defense response relationship: regulates GO:0006952 ! defense response [Term] id: GO:0031348 name: negative regulation of defense response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." [GOC:mah] synonym: "down regulation of defense response" EXACT [] synonym: "down-regulation of defense response" EXACT [] synonym: "downregulation of defense response" EXACT [] synonym: "inhibition of defense response" NARROW [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006952 ! defense response relationship: negatively_regulates GO:0006952 ! defense response [Term] id: GO:0031349 name: positive regulation of defense response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a defense response." [GOC:mah] synonym: "activation of defense response" NARROW [] synonym: "stimulation of defense response" NARROW [] synonym: "up regulation of defense response" EXACT [] synonym: "up-regulation of defense response" EXACT [] synonym: "upregulation of defense response" EXACT [] is_a: GO:0031347 ! regulation of defense response is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006952 ! defense response relationship: positively_regulates GO:0006952 ! defense response [Term] id: GO:0031410 name: cytoplasmic vesicle namespace: cellular_component alt_id: GO:0016023 def: "A vesicle found in the cytoplasm of a cell." [GOC:ai, GOC:mah, GOC:vesicles] subset: goslim_agr subset: goslim_candida subset: goslim_chembl subset: goslim_generic subset: goslim_mouse subset: goslim_yeast synonym: "cytoplasmic membrane bounded vesicle" RELATED [] synonym: "cytoplasmic membrane-enclosed vesicle" RELATED [] synonym: "cytoplasmic, membrane-bounded vesicle" RELATED [] xref: NIF_Subcellular:sao180601769 is_a: GO:0097708 ! intracellular vesicle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0031503 name: protein-containing complex localization namespace: biological_process alt_id: GO:0034629 def: "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." [GOC:mah] synonym: "cellular protein complex localisation" RELATED [GOC:mah] synonym: "cellular protein complex localization" RELATED [] synonym: "cellular protein-containing complex localization" RELATED [] synonym: "establishment and maintenance of cellular protein complex localization" RELATED [] synonym: "establishment and maintenance of protein complex localization" EXACT [] synonym: "protein complex localisation" EXACT [GOC:mah] synonym: "protein complex localization" RELATED [] is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0032991 ! protein-containing complex relationship: has_primary_input GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI [Term] id: GO:0031514 name: motile cilium namespace: cellular_component alt_id: GO:0009434 alt_id: GO:0031512 def: "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." [GOC:cilia, GOC:dgh, GOC:kmv, PMID:17009929, PMID:20144998, PMID:22118931] synonym: "microtubule-based flagellum" RELATED [] synonym: "motile cilia" EXACT [] synonym: "motile primary cilia" RELATED [] synonym: "motile primary cilium" RELATED [] synonym: "motile secondary cilium" RELATED [] synonym: "nodal cilium" RELATED [] is_a: GO:0005929 ! cilium intersection_of: GO:0005929 ! cilium intersection_of: capable_of GO:0003341 ! cilium movement relationship: capable_of GO:0003341 ! cilium movement [Term] id: GO:0031594 name: neuromuscular junction namespace: cellular_component def: "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." [GOC:nln] comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT. synonym: "motor endplate" RELATED [NIF_Subcellular:nlx_subcell_20090512] synonym: "NMJ" RELATED [GOC:ha] xref: NIF_Subcellular:sao1124888485 xref: Wikipedia:Neuromuscular_junction is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: overlaps CL:0000100 ! motor neuron intersection_of: overlaps CL:0000187 ! muscle cell relationship: overlaps CL:0000100 ! motor neuron relationship: overlaps CL:0000187 ! muscle cell [Term] id: GO:0031641 name: regulation of myelination namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042552 ! myelination relationship: regulates GO:0042552 ! myelination [Term] id: GO:0031642 name: negative regulation of myelination namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] synonym: "down regulation of myelination" EXACT [] synonym: "down-regulation of myelination" EXACT [] synonym: "downregulation of myelination" EXACT [] synonym: "inhibition of myelination" NARROW [] is_a: GO:0031641 ! regulation of myelination is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042552 ! myelination relationship: negatively_regulates GO:0042552 ! myelination [Term] id: GO:0031643 name: positive regulation of myelination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons." [GOC:mah] synonym: "activation of myelination" NARROW [] synonym: "stimulation of myelination" NARROW [] synonym: "up regulation of myelination" EXACT [] synonym: "up-regulation of myelination" EXACT [] synonym: "upregulation of myelination" EXACT [] is_a: GO:0031641 ! regulation of myelination is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042552 ! myelination relationship: positively_regulates GO:0042552 ! myelination [Term] id: GO:0031644 name: regulation of nervous system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." [GOC:dph, GOC:mah, GOC:tb] synonym: "regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "regulation of neurological system process" EXACT [] synonym: "regulation of neurophysiological process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050877 ! nervous system process relationship: regulates GO:0050877 ! nervous system process [Term] id: GO:0031645 name: negative regulation of nervous system process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "down regulation of neurological process" EXACT [] synonym: "down-regulation of neurological process" EXACT [] synonym: "downregulation of neurological process" EXACT [] synonym: "inhibition of neurological process" NARROW [] synonym: "negative regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of neurological system process" EXACT [] synonym: "negative regulation of neurophysiological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050877 ! nervous system process relationship: negatively_regulates GO:0050877 ! nervous system process [Term] id: GO:0031646 name: positive regulation of nervous system process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." [GOC:dph, GOC:mah, GOC:tb] synonym: "activation of neurological process" NARROW [] synonym: "positive regulation of neurological process" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of neurological system process" EXACT [] synonym: "positive regulation of neurophysiological process" EXACT [] synonym: "stimulation of neurological process" NARROW [] synonym: "up regulation of neurological process" EXACT [] synonym: "up-regulation of neurological process" EXACT [] synonym: "upregulation of neurological process" EXACT [] is_a: GO:0031644 ! regulation of nervous system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050877 ! nervous system process relationship: positively_regulates GO:0050877 ! nervous system process [Term] id: GO:0031965 name: nuclear membrane namespace: cellular_component def: "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." [GOC:mah, GOC:pz] xref: NIF_Subcellular:sao1687101204 is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0005635 ! nuclear envelope [Term] id: GO:0031967 name: organelle envelope namespace: cellular_component def: "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." [GOC:mah, GOC:pz] subset: goslim_mouse is_a: GO:0031975 ! envelope relationship: part_of GO:0043227 ! membrane-bounded organelle relationship: part_of GO:0043229 ! intracellular organelle [Term] id: GO:0031968 name: organelle outer membrane namespace: cellular_component def: "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." [GOC:mah] is_a: GO:0019867 ! outer membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043226 ! organelle intersection_of: part_of GO:0031967 ! organelle envelope relationship: part_of GO:0031967 ! organelle envelope [Term] id: GO:0031974 name: membrane-enclosed lumen namespace: cellular_component def: "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." [GOC:add, GOC:mah] is_a: GO:0110165 ! cellular anatomical entity disjoint_from: GO:0045202 ! synapse [Term] id: GO:0031975 name: envelope namespace: cellular_component def: "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." [GOC:mah, GOC:pz] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell [Term] id: GO:0031981 name: nuclear lumen namespace: cellular_component def: "The volume enclosed by the nuclear inner membrane." [GOC:mah, GOC:pz] is_a: GO:0070013 ! intracellular organelle lumen relationship: part_of GO:0005634 ! nucleus [Term] id: GO:0031982 name: vesicle namespace: cellular_component alt_id: GO:0031988 def: "Any small, fluid-filled, spherical organelle enclosed by membrane." [GOC:mah, GOC:pz, GOC:vesicles] subset: goslim_pir synonym: "membrane-bounded vesicle" RELATED [] synonym: "membrane-enclosed vesicle" RELATED [] xref: NIF_Subcellular:sao221389602 xref: Wikipedia:Vesicle_(biology) is_a: GO:0043227 ! membrane-bounded organelle [Term] id: GO:0031987 name: locomotion involved in locomotory behavior namespace: biological_process def: "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:mah] synonym: "locomotion during locomotory behaviour" EXACT [] is_a: GO:0040011 ! locomotion intersection_of: GO:0040011 ! locomotion intersection_of: part_of GO:0007626 ! locomotory behavior relationship: part_of GO:0007626 ! locomotory behavior [Term] id: GO:0032024 name: positive regulation of insulin secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." [GOC:mah] synonym: "activation of insulin secretion" NARROW [] synonym: "stimulation of insulin secretion" NARROW [] synonym: "up regulation of insulin secretion" EXACT [] synonym: "up-regulation of insulin secretion" EXACT [] synonym: "upregulation of insulin secretion" EXACT [] is_a: GO:0050714 ! positive regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030073 ! insulin secretion relationship: positively_regulates GO:0030073 ! insulin secretion [Term] id: GO:0032057 name: negative regulation of translational initiation in response to stress namespace: biological_process def: "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "down regulation of translation initiation in response to stress" EXACT [] synonym: "down-regulation of translation initiation in response to stress" EXACT [] synonym: "downregulation of translation initiation in response to stress" EXACT [] synonym: "inhibition of translation initiation in response to stress" NARROW [] is_a: GO:0045947 ! negative regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006413 ! translational initiation intersection_of: part_of GO:0006950 ! response to stress relationship: part_of GO:0006950 ! response to stress [Term] id: GO:0032058 name: positive regulation of translational initiation in response to stress namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." [GOC:mah] synonym: "activation of translation initiation in response to stress" NARROW [] synonym: "stimulation of translation initiation in response to stress" NARROW [] synonym: "up regulation of translation initiation in response to stress" EXACT [] synonym: "up-regulation of translation initiation in response to stress" EXACT [] synonym: "upregulation of translation initiation in response to stress" EXACT [] is_a: GO:0045948 ! positive regulation of translational initiation intersection_of: GO:0065007 ! biological regulation intersection_of: part_of GO:0006950 ! response to stress intersection_of: positively_regulates GO:0006413 ! translational initiation relationship: part_of GO:0006950 ! response to stress [Term] id: GO:0032059 name: bleb namespace: cellular_component def: "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] subset: goslim_pir synonym: "plasma membrane bleb" EXACT [GOC:pr] xref: Wikipedia:Bleb_(cell_biology) is_a: GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0032060 name: bleb assembly namespace: biological_process def: "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." [GOC:mah, GOC:mtg_apoptosis, PMID:12083798, PMID:16624291, Wikipedia:Bleb_(cell_biology)] synonym: "blebbing" BROAD [GOC:pr] synonym: "cell blebbing" EXACT [] synonym: "membrane blebbing" BROAD [GOC:pr] synonym: "plasma membrane bleb assembly" EXACT [GOC:pr] synonym: "plasma membrane blebbing" EXACT [GOC:pr] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032059 ! bleb relationship: results_in_assembly_of GO:0032059 ! bleb [Term] id: GO:0032069 name: regulation of nuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "nuclease regulator activity" RELATED [] is_a: GO:0051336 ! regulation of hydrolase activity is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0004518 ! nuclease activity relationship: regulates GO:0004518 ! nuclease activity [Term] id: GO:0032070 name: regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "deoxyribonuclease regulator" RELATED [] synonym: "DNase regulator" RELATED [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0004536 ! DNA nuclease activity relationship: regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032074 name: negative regulation of nuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "down regulation of nuclease activity" EXACT [] synonym: "down-regulation of nuclease activity" EXACT [] synonym: "downregulation of nuclease activity" EXACT [] synonym: "inhibition of nuclease activity" NARROW [] synonym: "nuclease inhibitor" RELATED [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051346 ! negative regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0004518 ! nuclease activity relationship: negatively_regulates GO:0004518 ! nuclease activity [Term] id: GO:0032075 name: positive regulation of nuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "activation of nuclease activity" NARROW [] synonym: "nuclease activator" RELATED [] synonym: "stimulation of nuclease activity" NARROW [] synonym: "up regulation of nuclease activity" EXACT [] synonym: "up-regulation of nuclease activity" EXACT [] synonym: "upregulation of nuclease activity" EXACT [] is_a: GO:0032069 ! regulation of nuclease activity is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051345 ! positive regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0004518 ! nuclease activity relationship: positively_regulates GO:0004518 ! nuclease activity [Term] id: GO:0032076 name: negative regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "deoxyribonuclease inhibitor" RELATED [] synonym: "DNase inhibitor" RELATED [] synonym: "down regulation of deoxyribonuclease activity" EXACT [] synonym: "down-regulation of deoxyribonuclease activity" EXACT [] synonym: "downregulation of deoxyribonuclease activity" EXACT [] synonym: "inhibition of deoxyribonuclease activity" NARROW [] is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032074 ! negative regulation of nuclease activity is_a: GO:0051053 ! negative regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0004536 ! DNA nuclease activity relationship: negatively_regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032077 name: positive regulation of deoxyribonuclease activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "activation of deoxyribonuclease activity" NARROW [] synonym: "deoxyribonuclease activator" RELATED [] synonym: "DNase activator" RELATED [] synonym: "stimulation of deoxyribonuclease activity" NARROW [] synonym: "up regulation of deoxyribonuclease activity" EXACT [] synonym: "up-regulation of deoxyribonuclease activity" EXACT [] synonym: "upregulation of deoxyribonuclease activity" EXACT [] is_a: GO:0032070 ! regulation of deoxyribonuclease activity is_a: GO:0032075 ! positive regulation of nuclease activity is_a: GO:0051054 ! positive regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0004536 ! DNA nuclease activity relationship: positively_regulates GO:0004536 ! DNA nuclease activity [Term] id: GO:0032101 name: regulation of response to external stimulus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009605 ! response to external stimulus relationship: regulates GO:0009605 ! response to external stimulus [Term] id: GO:0032102 name: negative regulation of response to external stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "down regulation of response to external stimulus" EXACT [] synonym: "down-regulation of response to external stimulus" EXACT [] synonym: "downregulation of response to external stimulus" EXACT [] synonym: "inhibition of response to external stimulus" NARROW [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048585 ! negative regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009605 ! response to external stimulus relationship: negatively_regulates GO:0009605 ! response to external stimulus [Term] id: GO:0032103 name: positive regulation of response to external stimulus namespace: biological_process def: "Any process that activates, maintains or increases the rate of a response to an external stimulus." [GOC:mah] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "activation of response to external stimulus" NARROW [] synonym: "stimulation of response to external stimulus" NARROW [] synonym: "up regulation of response to external stimulus" EXACT [] synonym: "up-regulation of response to external stimulus" EXACT [] synonym: "upregulation of response to external stimulus" EXACT [] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0048584 ! positive regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009605 ! response to external stimulus relationship: positively_regulates GO:0009605 ! response to external stimulus [Term] id: GO:0032222 name: regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007271 ! synaptic transmission, cholinergic relationship: regulates GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0032223 name: negative regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "down regulation of synaptic transmission, cholinergic" EXACT [] synonym: "down-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "downregulation of synaptic transmission, cholinergic" EXACT [] synonym: "inhibition of synaptic transmission, cholinergic" NARROW [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050805 ! negative regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic relationship: negatively_regulates GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0032224 name: positive regulation of synaptic transmission, cholinergic namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." [GOC:mah] synonym: "activation of synaptic transmission, cholinergic" NARROW [] synonym: "stimulation of synaptic transmission, cholinergic" NARROW [] synonym: "up regulation of synaptic transmission, cholinergic" EXACT [] synonym: "up-regulation of synaptic transmission, cholinergic" EXACT [] synonym: "upregulation of synaptic transmission, cholinergic" EXACT [] is_a: GO:0032222 ! regulation of synaptic transmission, cholinergic is_a: GO:0050806 ! positive regulation of synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007271 ! synaptic transmission, cholinergic relationship: positively_regulates GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0032231 name: regulation of actin filament bundle assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "regulation of actin cable assembly" EXACT [GOC:dph, GOC:tb] synonym: "regulation of actin filament bundle formation" RELATED [GOC:dph] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0110053 ! regulation of actin filament organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051017 ! actin filament bundle assembly relationship: regulates GO:0051017 ! actin filament bundle assembly [Term] id: GO:0032232 name: negative regulation of actin filament bundle assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "down regulation of actin filament bundle formation" EXACT [] synonym: "down-regulation of actin filament bundle formation" EXACT [] synonym: "downregulation of actin filament bundle formation" EXACT [] synonym: "inhibition of actin filament bundle formation" NARROW [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051017 ! actin filament bundle assembly relationship: negatively_regulates GO:0051017 ! actin filament bundle assembly [Term] id: GO:0032233 name: positive regulation of actin filament bundle assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." [GOC:mah] synonym: "activation of actin filament bundle formation" NARROW [] synonym: "stimulation of actin filament bundle formation" NARROW [] synonym: "up regulation of actin filament bundle formation" EXACT [] synonym: "up-regulation of actin filament bundle formation" EXACT [] synonym: "upregulation of actin filament bundle formation" EXACT [] is_a: GO:0032231 ! regulation of actin filament bundle assembly is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051017 ! actin filament bundle assembly relationship: positively_regulates GO:0051017 ! actin filament bundle assembly [Term] id: GO:0032239 name: regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015931 ! nucleobase-containing compound transport relationship: regulates GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0032240 name: negative regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015931 ! nucleobase-containing compound transport relationship: negatively_regulates GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0032241 name: positive regulation of nucleobase-containing compound transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" RELATED [GOC:dph, GOC:tb] synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" NARROW [] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" EXACT [] is_a: GO:0032239 ! regulation of nucleobase-containing compound transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015931 ! nucleobase-containing compound transport relationship: positively_regulates GO:0015931 ! nucleobase-containing compound transport [Term] id: GO:0032252 name: secretory granule localization namespace: biological_process def: "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." [GOC:mah] synonym: "secretory granule clustering" RELATED [] synonym: "secretory granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0030141 ! secretory granule relationship: has_primary_input GO:0030141 ! secretory granule [Term] id: GO:0032271 name: regulation of protein polymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "regulation of protein polymerisation" EXACT [] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051258 ! protein polymerization relationship: regulates GO:0051258 ! protein polymerization [Term] id: GO:0032272 name: negative regulation of protein polymerization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "down regulation of protein polymerization" EXACT [] synonym: "down-regulation of protein polymerization" EXACT [] synonym: "downregulation of protein polymerization" EXACT [] synonym: "inhibition of protein polymerization" NARROW [] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051258 ! protein polymerization relationship: negatively_regulates GO:0051258 ! protein polymerization [Term] id: GO:0032273 name: positive regulation of protein polymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." [GOC:mah] synonym: "activation of protein polymerization" NARROW [] synonym: "stimulation of protein polymerization" NARROW [] synonym: "up regulation of protein polymerization" EXACT [] synonym: "up-regulation of protein polymerization" EXACT [] synonym: "upregulation of protein polymerization" EXACT [] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:0032271 ! regulation of protein polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051258 ! protein polymerization relationship: positively_regulates GO:0051258 ! protein polymerization [Term] id: GO:0032288 name: myelin assembly namespace: biological_process def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system." [GOC:dgh, GOC:dph, GOC:tb] synonym: "myelin formation" RELATED [GOC:dph, GOC:tb] is_a: GO:0010927 ! cellular component assembly involved in morphogenesis intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0043209 ! myelin sheath relationship: part_of GO:0042552 ! myelination relationship: results_in_assembly_of GO:0043209 ! myelin sheath [Term] id: GO:0032289 name: central nervous system myelin formation namespace: biological_process def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system." [GOC:dgh] synonym: "myelin formation in central nervous system" EXACT [] is_a: GO:0032288 ! myelin assembly intersection_of: GO:0032288 ! myelin assembly intersection_of: occurs_in UBERON:0001017 ! central nervous system relationship: in_taxon NCBITaxon:33213 {all_only="true"} ! Bilateria relationship: occurs_in UBERON:0001017 ! central nervous system relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of GO:0022010 ! central nervous system myelination [Term] id: GO:0032290 name: peripheral nervous system myelin formation namespace: biological_process def: "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system." [GOC:dgh] synonym: "myelin formation in peripheral nervous system" EXACT [] is_a: GO:0032288 ! myelin assembly intersection_of: GO:0032288 ! myelin assembly intersection_of: occurs_in UBERON:0000010 ! peripheral nervous system relationship: occurs_in UBERON:0000010 ! peripheral nervous system relationship: part_of GO:0022011 ! myelination in peripheral nervous system property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19106" xsd:anyURI [Term] id: GO:0032291 name: axon ensheathment in central nervous system namespace: biological_process def: "The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh] synonym: "ensheathment of axons in central nervous system" EXACT [] is_a: GO:0008366 ! axon ensheathment intersection_of: GO:0008366 ! axon ensheathment intersection_of: occurs_in UBERON:0001017 ! central nervous system relationship: in_taxon NCBITaxon:33213 {all_only="true"} ! Bilateria relationship: occurs_in UBERON:0001017 ! central nervous system relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: GO:0032292 name: peripheral nervous system axon ensheathment namespace: biological_process def: "The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction." [GOC:dgh] synonym: "ensheathment of axons in peripheral nervous system" EXACT [] is_a: GO:0008366 ! axon ensheathment intersection_of: GO:0008366 ! axon ensheathment intersection_of: occurs_in UBERON:0000010 ! peripheral nervous system relationship: occurs_in UBERON:0000010 ! peripheral nervous system [Term] id: GO:0032330 name: regulation of chondrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002062 ! chondrocyte differentiation relationship: regulates GO:0002062 ! chondrocyte differentiation [Term] id: GO:0032331 name: negative regulation of chondrocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "down regulation of chondrocyte differentiation" EXACT [] synonym: "down-regulation of chondrocyte differentiation" EXACT [] synonym: "downregulation of chondrocyte differentiation" EXACT [] synonym: "inhibition of chondrocyte differentiation" NARROW [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0061037 ! negative regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002062 ! chondrocyte differentiation relationship: negatively_regulates GO:0002062 ! chondrocyte differentiation [Term] id: GO:0032332 name: positive regulation of chondrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." [GOC:mah] synonym: "activation of chondrocyte differentiation" NARROW [] synonym: "stimulation of chondrocyte differentiation" NARROW [] synonym: "up regulation of chondrocyte differentiation" EXACT [] synonym: "up-regulation of chondrocyte differentiation" EXACT [] synonym: "upregulation of chondrocyte differentiation" EXACT [] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0061036 ! positive regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002062 ! chondrocyte differentiation relationship: positively_regulates GO:0002062 ! chondrocyte differentiation [Term] id: GO:0032365 name: intracellular lipid transport namespace: biological_process def: "The directed movement of lipids within cells." [GOC:mah] is_a: GO:0006869 ! lipid transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure [Term] id: GO:0032368 name: regulation of lipid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006869 ! lipid transport relationship: regulates GO:0006869 ! lipid transport [Term] id: GO:0032369 name: negative regulation of lipid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of lipid transport" EXACT [] synonym: "down-regulation of lipid transport" EXACT [] synonym: "downregulation of lipid transport" EXACT [] synonym: "inhibition of lipid transport" NARROW [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051051 ! negative regulation of transport is_a: GO:1905953 ! negative regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006869 ! lipid transport relationship: negatively_regulates GO:0006869 ! lipid transport [Term] id: GO:0032370 name: positive regulation of lipid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of lipid transport" NARROW [] synonym: "stimulation of lipid transport" NARROW [] synonym: "up regulation of lipid transport" EXACT [] synonym: "up-regulation of lipid transport" EXACT [] synonym: "upregulation of lipid transport" EXACT [] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0051050 ! positive regulation of transport is_a: GO:1905954 ! positive regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006869 ! lipid transport relationship: positively_regulates GO:0006869 ! lipid transport [Term] id: GO:0032377 name: regulation of intracellular lipid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032365 ! intracellular lipid transport relationship: regulates GO:0032365 ! intracellular lipid transport [Term] id: GO:0032378 name: negative regulation of intracellular lipid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "down regulation of intracellular lipid transport" EXACT [] synonym: "down-regulation of intracellular lipid transport" EXACT [] synonym: "downregulation of intracellular lipid transport" EXACT [] synonym: "inhibition of intracellular lipid transport" NARROW [] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032387 ! negative regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032365 ! intracellular lipid transport relationship: negatively_regulates GO:0032365 ! intracellular lipid transport [Term] id: GO:0032379 name: positive regulation of intracellular lipid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." [GOC:mah] synonym: "activation of intracellular lipid transport" NARROW [] synonym: "stimulation of intracellular lipid transport" NARROW [] synonym: "up regulation of intracellular lipid transport" EXACT [] synonym: "up-regulation of intracellular lipid transport" EXACT [] synonym: "upregulation of intracellular lipid transport" EXACT [] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0032377 ! regulation of intracellular lipid transport is_a: GO:0032388 ! positive regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032365 ! intracellular lipid transport relationship: positively_regulates GO:0032365 ! intracellular lipid transport [Term] id: GO:0032386 name: regulation of intracellular transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] is_a: GO:0051049 ! regulation of transport is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046907 ! intracellular transport relationship: regulates GO:0046907 ! intracellular transport [Term] id: GO:0032387 name: negative regulation of intracellular transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "down regulation of intracellular transport" EXACT [] synonym: "down-regulation of intracellular transport" EXACT [] synonym: "downregulation of intracellular transport" EXACT [] synonym: "inhibition of intracellular transport" NARROW [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046907 ! intracellular transport relationship: negatively_regulates GO:0046907 ! intracellular transport [Term] id: GO:0032388 name: positive regulation of intracellular transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." [GOC:mah] synonym: "activation of intracellular transport" NARROW [] synonym: "stimulation of intracellular transport" NARROW [] synonym: "up regulation of intracellular transport" EXACT [] synonym: "up-regulation of intracellular transport" EXACT [] synonym: "upregulation of intracellular transport" EXACT [] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046907 ! intracellular transport relationship: positively_regulates GO:0046907 ! intracellular transport [Term] id: GO:0032409 name: regulation of transporter activity namespace: biological_process def: "Any process that modulates the activity of a transporter." [GOC:mah] subset: term_scheduled_for_obsoletion is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005215 ! transporter activity relationship: regulates GO:0005215 ! transporter activity [Term] id: GO:0032410 name: negative regulation of transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of a transporter." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "down regulation of transporter activity" EXACT [] synonym: "down-regulation of transporter activity" EXACT [] synonym: "downregulation of transporter activity" EXACT [] synonym: "inhibition of transporter activity" NARROW [] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005215 ! transporter activity relationship: negatively_regulates GO:0005215 ! transporter activity [Term] id: GO:0032411 name: positive regulation of transporter activity namespace: biological_process def: "Any process that activates or increases the activity of a transporter." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "activation of transporter activity" NARROW [] synonym: "stimulation of transporter activity" NARROW [] synonym: "up regulation of transporter activity" EXACT [] synonym: "up-regulation of transporter activity" EXACT [] synonym: "upregulation of transporter activity" EXACT [] is_a: GO:0032409 ! regulation of transporter activity is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005215 ! transporter activity relationship: positively_regulates GO:0005215 ! transporter activity [Term] id: GO:0032412 name: regulation of monoatomic ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the activity of an ion transporter." [GOC:mah, GOC:tb] subset: term_scheduled_for_obsoletion synonym: "regulation of ion transmembrane transporter activity" BROAD [] synonym: "regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0022898 ! regulation of transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015075 ! monoatomic ion transmembrane transporter activity relationship: regulates GO:0015075 ! monoatomic ion transmembrane transporter activity [Term] id: GO:0032413 name: negative regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that stops or reduces the activity of an ion transporter." [GOC:mah, GOC:tb] subset: term_scheduled_for_obsoletion synonym: "down regulation of ion transporter activity" EXACT [] synonym: "down-regulation of ion transporter activity" EXACT [] synonym: "downregulation of ion transporter activity" EXACT [] synonym: "inhibition of ion transporter activity" NARROW [] synonym: "negative regulation of ion transporter activity" EXACT [GOC:tb] is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity relationship: negatively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity [Term] id: GO:0032414 name: positive regulation of ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the activity of an ion transporter." [GOC:mah, GOC:tb] subset: term_scheduled_for_obsoletion synonym: "activation of ion transporter activity" NARROW [] synonym: "positive regulation of ion transporter activity" EXACT [GOC:tb] synonym: "stimulation of ion transporter activity" NARROW [] synonym: "up regulation of ion transporter activity" EXACT [] synonym: "up-regulation of ion transporter activity" EXACT [] synonym: "upregulation of ion transporter activity" EXACT [] is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity relationship: positively_regulates GO:0015075 ! monoatomic ion transmembrane transporter activity [Term] id: GO:0032432 name: actin filament bundle namespace: cellular_component alt_id: GO:0000141 alt_id: GO:0030482 def: "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:mah] synonym: "actin cable" RELATED [GOC:mah] is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005884 ! actin filament relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0032501 name: multicellular organismal process namespace: biological_process alt_id: GO:0044707 alt_id: GO:0050874 def: "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." [GOC:curators, GOC:dph, GOC:isa_complete, GOC:tb] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "organismal physiological process" EXACT [] synonym: "single-multicellular organism process" RELATED [] is_a: GO:0008150 ! biological_process property_value: RO:0002161 NCBITaxon:2 property_value: RO:0002161 NCBITaxon:2157 property_value: RO:0002161 NCBITaxon:4896 property_value: RO:0002161 NCBITaxon:4932 created_by: jl creation_date: 2012-09-19T16:07:47Z [Term] id: GO:0032502 name: developmental process namespace: biological_process alt_id: GO:0044767 def: "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." [GOC:isa_complete] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_pir synonym: "development" NARROW [] synonym: "single-organism developmental process" RELATED [] is_a: GO:0008150 ! biological_process created_by: jl creation_date: 2012-12-19T12:21:31Z [Term] id: GO:0032504 name: multicellular organism reproduction namespace: biological_process def: "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." [GOC:isa_complete, GOC:jid] subset: goslim_drosophila is_a: GO:0000003 ! reproduction is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0032528 name: microvillus organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." [GOC:mah] synonym: "microvillus organisation" EXACT [GOC:mah] synonym: "microvillus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005902 ! microvillus relationship: results_in_organization_of GO:0005902 ! microvillus property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0032530 name: regulation of microvillus organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." [GOC:mah] synonym: "regulation of microvillus organisation" EXACT [GOC:mah] synonym: "regulation of microvillus organization and biogenesis" RELATED [GOC:mah] is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032528 ! microvillus organization relationship: regulates GO:0032528 ! microvillus organization [Term] id: GO:0032534 name: regulation of microvillus assembly namespace: biological_process def: "A process that modulates the formation of a microvillus." [GOC:mah] synonym: "regulation of microvillus biogenesis" RELATED [GOC:mah] is_a: GO:0032530 ! regulation of microvillus organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030033 ! microvillus assembly relationship: regulates GO:0030033 ! microvillus assembly [Term] id: GO:0032589 name: neuron projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a neuron projection." [GOC:mah] is_a: GO:0031253 ! cell projection membrane is_a: GO:0031256 ! leading edge membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043005 ! neuron projection relationship: bounding_layer_of GO:0043005 ! neuron projection relationship: part_of GO:0043005 ! neuron projection [Term] id: GO:0032594 name: protein transport within lipid bilayer namespace: biological_process def: "The directed movement of a protein from one location to another within a lipid bilayer." [GOC:mah] synonym: "protein translocation within membrane" EXACT [] synonym: "receptor translocation within membrane" NARROW [] synonym: "receptor transport within lipid bilayer" NARROW [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0061024 ! membrane organization intersection_of: GO:0015031 ! protein transport intersection_of: occurs_in GO:0016020 ! membrane relationship: occurs_in GO:0016020 ! membrane [Term] id: GO:0032774 name: RNA biosynthetic process namespace: biological_process alt_id: GO:0062103 def: "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." [GOC:mah, GOC:txnOH] comment: Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study. subset: gocheck_do_not_annotate synonym: "double-stranded RNA biosynthesis" NARROW [] synonym: "double-stranded RNA biosynthetic process" NARROW [] synonym: "dsRNA biosynthesis" NARROW [] synonym: "dsRNA biosynthetic process" NARROW [GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:rl] synonym: "RNA anabolism" EXACT [] synonym: "RNA biosynthesis" EXACT [] synonym: "RNA formation" EXACT [] synonym: "RNA synthesis" EXACT [] is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0016070 ! RNA metabolic process is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33697 ! ribonucleic acid relationship: has_primary_output CHEBI:33697 ! ribonucleic acid [Term] id: GO:0032782 name: bile acid secretion namespace: biological_process def: "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." [GOC:ecd] is_a: GO:0015718 ! monocarboxylic acid transport is_a: GO:0046717 ! acid secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:36235 ! bile acid anion relationship: has_primary_input CHEBI:36235 ! bile acid anion [Term] id: GO:0032787 name: monocarboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." [GOC:vk] subset: goslim_yeast synonym: "monocarboxylate metabolic process" EXACT [] synonym: "monocarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_input_or_output CHEBI:35757 ! monocarboxylic acid anion [Term] id: GO:0032790 name: ribosome disassembly namespace: biological_process def: "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." [GOC:mah, GOC:vk] synonym: "ribosome dissociation factor" RELATED [] synonym: "ribosome recycling" NARROW [GOC:db, PMID:9463391] is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005840 ! ribosome relationship: results_in_disassembly_of GO:0005840 ! ribosome [Term] id: GO:0032838 name: plasma membrane bounded cell projection cytoplasm namespace: cellular_component def: "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." [GOC:krc, GOC:mah] is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0120025 ! plasma membrane bounded cell projection relationship: part_of GO:0120025 ! plasma membrane bounded cell projection [Term] id: GO:0032868 name: response to insulin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." [GOC:mah, ISBN:0198506732] synonym: "response to insulin stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0042221 ! response to chemical intersection_of: has_input PR:000009054 ! insulin gene translation product relationship: has_input PR:000009054 ! insulin gene translation product [Term] id: GO:0032871 name: regulation of karyogamy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." [GOC:mah] is_a: GO:1903353 ! regulation of nucleus organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000741 ! karyogamy relationship: regulates GO:0000741 ! karyogamy [Term] id: GO:0032878 name: regulation of establishment or maintenance of cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007163 ! establishment or maintenance of cell polarity relationship: regulates GO:0007163 ! establishment or maintenance of cell polarity [Term] id: GO:0032879 name: regulation of localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." [GOC:mah] synonym: "regulation of localisation" EXACT [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051179 ! localization relationship: regulates GO:0051179 ! localization [Term] id: GO:0032880 name: regulation of protein localization namespace: biological_process alt_id: GO:1903827 def: "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." [GOC:dph, GOC:mah, GOC:tb] subset: goslim_chembl synonym: "regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein localization" EXACT [] synonym: "regulation of protein localisation" EXACT [GOC:mah] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008104 ! protein localization relationship: regulates GO:0008104 ! protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:14Z [Term] id: GO:0032881 name: regulation of polysaccharide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." [GOC:mah] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005976 ! polysaccharide metabolic process relationship: regulates GO:0005976 ! polysaccharide metabolic process [Term] id: GO:0032885 name: regulation of polysaccharide biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." [GOC:mah] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043255 ! regulation of carbohydrate biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000271 ! polysaccharide biosynthetic process relationship: regulates GO:0000271 ! polysaccharide biosynthetic process [Term] id: GO:0032886 name: regulation of microtubule-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007017 ! microtubule-based process relationship: regulates GO:0007017 ! microtubule-based process [Term] id: GO:0032890 name: regulation of organic acid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015849 ! organic acid transport relationship: regulates GO:0015849 ! organic acid transport [Term] id: GO:0032891 name: negative regulation of organic acid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "down regulation of organic acid transport" EXACT [] synonym: "down-regulation of organic acid transport" EXACT [] synonym: "downregulation of organic acid transport" EXACT [] synonym: "inhibition of organic acid transport" NARROW [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015849 ! organic acid transport relationship: negatively_regulates GO:0015849 ! organic acid transport [Term] id: GO:0032892 name: positive regulation of organic acid transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "activation of organic acid transport" NARROW [] synonym: "stimulation of organic acid transport" NARROW [] synonym: "up regulation of organic acid transport" EXACT [] synonym: "up-regulation of organic acid transport" EXACT [] synonym: "upregulation of organic acid transport" EXACT [] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015849 ! organic acid transport relationship: positively_regulates GO:0015849 ! organic acid transport [Term] id: GO:0032940 name: secretion by cell namespace: biological_process def: "The controlled release of a substance by a cell." [GOC:mah] synonym: "cellular secretion" EXACT [] xref: Wikipedia:Secretion is_a: GO:0046903 ! secretion is_a: GO:0140352 ! export from cell [Term] id: GO:0032941 name: secretion by tissue namespace: biological_process def: "The controlled release of a substance by a tissue." [GOC:mah] synonym: "expulsion of gland contents" RELATED [GOC:mah] synonym: "tissue secretion" EXACT [] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0046903 ! secretion [Term] id: GO:0032943 name: mononuclear cell proliferation namespace: biological_process def: "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." [GOC:add] synonym: "PBMC proliferation" NARROW [] synonym: "peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0070661 ! leukocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000842 ! mononuclear cell relationship: acts_on_population_of CL:0000842 ! mononuclear cell [Term] id: GO:0032944 name: regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "regulation of PBMC proliferation" NARROW [] synonym: "regulation of peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032943 ! mononuclear cell proliferation relationship: regulates GO:0032943 ! mononuclear cell proliferation [Term] id: GO:0032945 name: negative regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "negative regulation of PBMC proliferation" NARROW [] synonym: "negative regulation of peripheral blood mononuclear cell proliferation" NARROW [] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070664 ! negative regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032943 ! mononuclear cell proliferation relationship: negatively_regulates GO:0032943 ! mononuclear cell proliferation [Term] id: GO:0032946 name: positive regulation of mononuclear cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." [GOC:add] synonym: "activation of mononuclear cell proliferation" NARROW [] synonym: "positive regulation of PBMC proliferation" NARROW [] synonym: "positive regulation of peripheral blood mononuclear cell proliferation" NARROW [] synonym: "stimulation of mononuclear cell proliferation" NARROW [] synonym: "up regulation of mononuclear cell proliferation" EXACT [] synonym: "up-regulation of mononuclear cell proliferation" EXACT [] synonym: "upregulation of mononuclear cell proliferation" EXACT [] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0070665 ! positive regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032943 ! mononuclear cell proliferation relationship: positively_regulates GO:0032943 ! mononuclear cell proliferation [Term] id: GO:0032956 name: regulation of actin cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:mah] synonym: "regulation of actin cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of actin cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0032970 ! regulation of actin filament-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030036 ! actin cytoskeleton organization relationship: regulates GO:0030036 ! actin cytoskeleton organization [Term] id: GO:0032963 name: collagen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output GO:0005581 ! collagen trimer relationship: has_primary_input_or_output GO:0005581 ! collagen trimer [Term] id: GO:0032964 name: collagen biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." [GOC:mah, ISBN:0198506732] synonym: "collagen anabolism" EXACT [] synonym: "collagen biosynthesis" EXACT [] synonym: "collagen formation" EXACT [] synonym: "collagen synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0032963 ! collagen metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output GO:0005581 ! collagen trimer relationship: has_primary_output GO:0005581 ! collagen trimer [Term] id: GO:0032965 name: regulation of collagen biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "regulation of collagen anabolism" EXACT [] synonym: "regulation of collagen biosynthesis" EXACT [] synonym: "regulation of collagen formation" EXACT [] synonym: "regulation of collagen synthesis" EXACT [] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0010712 ! regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032964 ! collagen biosynthetic process relationship: regulates GO:0032964 ! collagen biosynthetic process [Term] id: GO:0032966 name: negative regulation of collagen biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "negative regulation of collagen anabolism" EXACT [] synonym: "negative regulation of collagen biosynthesis" EXACT [] synonym: "negative regulation of collagen formation" EXACT [] synonym: "negative regulation of collagen synthesis" EXACT [] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0010713 ! negative regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032964 ! collagen biosynthetic process relationship: negatively_regulates GO:0032964 ! collagen biosynthetic process [Term] id: GO:0032967 name: positive regulation of collagen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." [GOC:mah] synonym: "positive regulation of collagen anabolism" EXACT [] synonym: "positive regulation of collagen biosynthesis" EXACT [] synonym: "positive regulation of collagen formation" EXACT [] synonym: "positive regulation of collagen synthesis" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0010714 ! positive regulation of collagen metabolic process is_a: GO:0032965 ! regulation of collagen biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032964 ! collagen biosynthetic process relationship: positively_regulates GO:0032964 ! collagen biosynthetic process [Term] id: GO:0032970 name: regulation of actin filament-based process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030029 ! actin filament-based process relationship: regulates GO:0030029 ! actin filament-based process [Term] id: GO:0032984 name: protein-containing complex disassembly namespace: biological_process alt_id: GO:0034623 alt_id: GO:0043241 alt_id: GO:0043624 def: "The disaggregation of a protein-containing macromolecular complex into its constituent components." [GOC:mah] synonym: "cellular macromolecule complex disassembly" RELATED [] synonym: "cellular protein complex disassembly" RELATED [] synonym: "macromolecule complex disassembly" RELATED [] synonym: "protein complex disassembly" EXACT [] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0032991 ! protein-containing complex relationship: results_in_disassembly_of GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI [Term] id: GO:0032986 name: protein-DNA complex disassembly namespace: biological_process def: "The disaggregation of a protein-DNA complex into its constituent components." [GOC:mah] synonym: "DNA-protein complex disassembly" EXACT [GOC:mah] is_a: GO:0032984 ! protein-containing complex disassembly is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0032993 ! protein-DNA complex relationship: results_in_disassembly_of GO:0032993 ! protein-DNA complex [Term] id: GO:0032988 name: protein-RNA complex disassembly namespace: biological_process def: "The disaggregation of a protein-RNA complex into its constituent components." [GOC:mah] synonym: "ribonucleoprotein complex disassembly" EXACT [] synonym: "RNA-protein complex disassembly" EXACT [] synonym: "RNP complex disassembly" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly is_a: GO:0071826 ! protein-RNA complex organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:1990904 ! ribonucleoprotein complex relationship: results_in_disassembly_of GO:1990904 ! ribonucleoprotein complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI [Term] id: GO:0032989 name: cellular component morphogenesis namespace: biological_process def: "The process in which cellular structures, including whole cells or cell parts, are generated and organized." [GOC:dph, GOC:mah, GOC:tb] subset: goslim_pir synonym: "cellular structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis is_a: GO:0016043 ! cellular component organization is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0005575 ! cellular_component relationship: results_in_morphogenesis_of GO:0005575 ! cellular_component [Term] id: GO:0032990 name: cell part morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a cell part are generated and organized." [GOC:mah] is_a: GO:0032989 ! cellular component morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0110165 ! cellular anatomical entity relationship: results_in_morphogenesis_of GO:0110165 ! cellular anatomical entity [Term] id: GO:0032991 name: protein-containing complex namespace: cellular_component alt_id: GO:0043234 def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." [GOC:dos, GOC:mah] comment: A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole. subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "macromolecular complex" EXACT [] synonym: "macromolecule complex" EXACT [] synonym: "protein complex" NARROW [] synonym: "protein containing complex" EXACT [] synonym: "protein-protein complex" NARROW [] is_a: GO:0005575 ! cellular_component is_a: PR:000050567 ! protein-containing material entity disjoint_from: GO:0110165 ! cellular anatomical entity [Term] id: GO:0032993 name: protein-DNA complex namespace: cellular_component def: "A macromolecular complex containing both protein and DNA molecules." [GOC:mah] comment: Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here. subset: goslim_pir synonym: "DNA-protein complex" EXACT [GOC:mah] is_a: GO:0032991 ! protein-containing complex relationship: has_part CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0033002 name: muscle cell proliferation namespace: biological_process def: "The expansion of a muscle cell population by cell division." [CL:0000187, GOC:mah] synonym: "myocyte proliferation" EXACT [] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000187 ! muscle cell relationship: acts_on_population_of CL:0000187 ! muscle cell [Term] id: GO:0033013 name: tetrapyrrole metabolic process namespace: biological_process def: "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] subset: goslim_pombe subset: prokaryote_subset synonym: "tetrapyrrole metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole relationship: has_primary_input_or_output CHEBI:26932 ! tetrapyrrole [Term] id: GO:0033014 name: tetrapyrrole biosynthetic process namespace: biological_process def: "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole anabolism" EXACT [] synonym: "tetrapyrrole biosynthesis" EXACT [] synonym: "tetrapyrrole formation" EXACT [] synonym: "tetrapyrrole synthesis" EXACT [] is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0033013 ! tetrapyrrole metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:26932 ! tetrapyrrole relationship: has_primary_output CHEBI:26932 ! tetrapyrrole [Term] id: GO:0033015 name: tetrapyrrole catabolic process namespace: biological_process def: "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." [GOC:mah] synonym: "tetrapyrrole breakdown" EXACT [] synonym: "tetrapyrrole catabolism" EXACT [] synonym: "tetrapyrrole degradation" EXACT [] is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0033013 ! tetrapyrrole metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:26932 ! tetrapyrrole relationship: has_primary_input CHEBI:26932 ! tetrapyrrole [Term] id: GO:0033028 name: myeloid cell apoptotic process namespace: biological_process def: "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." [CL:0000763, GOC:add, GOC:mtg_apoptosis, PMID:11292031, PMID:15330259, PMID:17133093] synonym: "apoptosis of myeloid cells" EXACT [] synonym: "myeloid cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000763 ! myeloid cell relationship: occurs_in CL:0000763 ! myeloid cell [Term] id: GO:0033032 name: regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "regulation of myeloid cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033028 ! myeloid cell apoptotic process relationship: regulates GO:0033028 ! myeloid cell apoptotic process [Term] id: GO:0033033 name: negative regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "down regulation of myeloid cell apoptosis" EXACT [] synonym: "down-regulation of myeloid cell apoptosis" EXACT [] synonym: "downregulation of myeloid cell apoptosis" EXACT [] synonym: "inhibition of myeloid cell apoptosis" NARROW [] synonym: "negative regulation of myeloid cell apoptosis" NARROW [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033028 ! myeloid cell apoptotic process relationship: negatively_regulates GO:0033028 ! myeloid cell apoptotic process [Term] id: GO:0033034 name: positive regulation of myeloid cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." [GOC:add, GOC:mtg_apoptosis] synonym: "activation of myeloid cell apoptosis" NARROW [] synonym: "positive regulation of myeloid cell apoptosis" NARROW [] synonym: "stimulation of myeloid cell apoptosis" NARROW [] synonym: "up regulation of myeloid cell apoptosis" EXACT [] synonym: "up-regulation of myeloid cell apoptosis" EXACT [] synonym: "upregulation of myeloid cell apoptosis" EXACT [] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033028 ! myeloid cell apoptotic process relationship: positively_regulates GO:0033028 ! myeloid cell apoptotic process [Term] id: GO:0033036 name: macromolecule localization namespace: biological_process def: "Any process in which a macromolecule is transported to, or maintained in, a specific location." [GOC:mah] subset: goslim_flybase_ribbon synonym: "macromolecule localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization [Term] id: GO:0033037 name: polysaccharide localization namespace: biological_process def: "Any process in which a polysaccharide is transported to, or maintained in, a specific location." [GOC:mah] synonym: "polysaccharide localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization intersection_of: GO:0033036 ! macromolecule localization intersection_of: has_primary_input CHEBI:18154 ! polysaccharide relationship: has_primary_input CHEBI:18154 ! polysaccharide [Term] id: GO:0033043 name: regulation of organelle organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." [GOC:mah] subset: goslim_yeast synonym: "regulation of organelle organisation" EXACT [GOC:mah] synonym: "regulation of organelle organization and biogenesis" RELATED [GOC:mah] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006996 ! organelle organization relationship: regulates GO:0006996 ! organelle organization [Term] id: GO:0033044 name: regulation of chromosome organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." [GOC:mah] synonym: "regulation of chromosome organisation" EXACT [GOC:mah] synonym: "regulation of chromosome organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051276 ! chromosome organization relationship: regulates GO:0051276 ! chromosome organization [Term] id: GO:0033045 name: regulation of sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033044 ! regulation of chromosome organization is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000819 ! sister chromatid segregation relationship: regulates GO:0000819 ! sister chromatid segregation [Term] id: GO:0033046 name: negative regulation of sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation is_a: GO:0051985 ! negative regulation of chromosome segregation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000819 ! sister chromatid segregation relationship: negatively_regulates GO:0000819 ! sister chromatid segregation [Term] id: GO:0033047 name: regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033045 ! regulation of sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000070 ! mitotic sister chromatid segregation relationship: regulates GO:0000070 ! mitotic sister chromatid segregation [Term] id: GO:0033048 name: negative regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." [GOC:mah] is_a: GO:0033046 ! negative regulation of sister chromatid segregation is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation relationship: negatively_regulates GO:0000070 ! mitotic sister chromatid segregation [Term] id: GO:0033059 name: cellular pigmentation namespace: biological_process def: "The deposition or aggregation of coloring matter in a cell." [GOC:mtg_MIT_16mar07] is_a: GO:0009987 ! cellular process is_a: GO:0043473 ! pigmentation [Term] id: GO:0033157 name: regulation of intracellular protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." [GOC:mah] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0051223 ! regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006886 ! intracellular protein transport relationship: regulates GO:0006886 ! intracellular protein transport [Term] id: GO:0033238 name: regulation of amine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." [GOC:mah] synonym: "regulation of amine metabolism" EXACT [] synonym: "regulation of cellular amine metabolic process" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009308 ! amine metabolic process relationship: regulates GO:0009308 ! amine metabolic process [Term] id: GO:0033239 name: negative regulation of amine metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "negative regulation of amine metabolism" EXACT [] synonym: "negative regulation of cellular amine metabolic process" EXACT [] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009308 ! amine metabolic process relationship: negatively_regulates GO:0009308 ! amine metabolic process [Term] id: GO:0033240 name: positive regulation of amine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." [GOC:mah] synonym: "positive regulation of amine metabolism" EXACT [] synonym: "positive regulation of cellular amine metabolic process" EXACT [] is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009308 ! amine metabolic process relationship: positively_regulates GO:0009308 ! amine metabolic process [Term] id: GO:0033241 name: regulation of amine catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "regulation of amine breakdown" EXACT [] synonym: "regulation of amine catabolism" EXACT [] synonym: "regulation of amine degradation" EXACT [] synonym: "regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0033238 ! regulation of amine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009310 ! amine catabolic process relationship: regulates GO:0009310 ! amine catabolic process [Term] id: GO:0033242 name: negative regulation of amine catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "negative regulation of amine breakdown" EXACT [] synonym: "negative regulation of amine catabolism" EXACT [] synonym: "negative regulation of amine degradation" EXACT [] synonym: "negative regulation of cellular amine catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009310 ! amine catabolic process relationship: negatively_regulates GO:0009310 ! amine catabolic process [Term] id: GO:0033243 name: positive regulation of amine catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." [GOC:mah] synonym: "positive regulation of amine breakdown" EXACT [] synonym: "positive regulation of amine catabolism" EXACT [] synonym: "positive regulation of amine degradation" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0033241 ! regulation of amine catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009310 ! amine catabolic process relationship: positively_regulates GO:0009310 ! amine catabolic process [Term] id: GO:0033278 name: cell proliferation in midbrain namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." [GO_REF:0000021, GOC:dgf] synonym: "cell proliferation in mesencephalon" EXACT [] synonym: "mesencepahalic cell proliferation" RELATED [] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: occurs_in UBERON:0001891 ! midbrain relationship: occurs_in UBERON:0001891 ! midbrain relationship: part_of GO:0030901 ! midbrain development [Term] id: GO:0033363 name: secretory granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "secretory granule organisation" EXACT [GOC:mah] synonym: "secretory granule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030141 ! secretory granule relationship: part_of GO:0010256 ! endomembrane system organization relationship: results_in_organization_of GO:0030141 ! secretory granule [Term] id: GO:0033365 name: protein localization to organelle namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within an organelle." [GOC:mah] synonym: "protein localisation to organelle" EXACT [GOC:mah] synonym: "protein localization in organelle" EXACT [GOC:mah] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0043226 ! organelle relationship: has_target_end_location GO:0043226 ! organelle [Term] id: GO:0033366 name: protein localization to secretory granule namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a secretory granule." [GOC:mah] synonym: "protein localisation in secretory granule" EXACT [GOC:mah] synonym: "protein localization in secretory granule" EXACT [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0030141 ! secretory granule relationship: has_target_end_location GO:0030141 ! secretory granule [Term] id: GO:0033371 name: T cell secretory granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." [GOC:mah] synonym: "T cell secretory granule organisation" EXACT [GOC:mah] synonym: "T cell secretory granule organization and biogenesis" RELATED [GOC:mah] synonym: "T lymphocyte secretory granule organization" EXACT [] synonym: "T-cell secretory granule organization" EXACT [] synonym: "T-lymphocyte secretory granule maturation" RELATED [] synonym: "T-lymphocyte secretory granule organization" EXACT [] is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0016043 ! cellular component organization intersection_of: occurs_in CL:0000084 ! T cell intersection_of: results_in_organization_of GO:0030141 ! secretory granule relationship: occurs_in CL:0000084 ! T cell [Term] id: GO:0033604 name: negative regulation of catecholamine secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "down regulation of catecholamine secretion" EXACT [] synonym: "down-regulation of catecholamine secretion" EXACT [] synonym: "downregulation of catecholamine secretion" EXACT [] synonym: "inhibition of catecholamine secretion" NARROW [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050432 ! catecholamine secretion relationship: negatively_regulates GO:0050432 ! catecholamine secretion [Term] id: GO:0033605 name: positive regulation of catecholamine secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." [GOC:mah] synonym: "activation of catecholamine secretion" NARROW [] synonym: "stimulation of catecholamine secretion" NARROW [] synonym: "up regulation of catecholamine secretion" EXACT [] synonym: "up-regulation of catecholamine secretion" EXACT [] synonym: "upregulation of catecholamine secretion" EXACT [] is_a: GO:0050433 ! regulation of catecholamine secretion is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050432 ! catecholamine secretion relationship: positively_regulates GO:0050432 ! catecholamine secretion [Term] id: GO:0033673 name: negative regulation of kinase activity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "down regulation of kinase activity" EXACT [] synonym: "down-regulation of kinase activity" EXACT [] synonym: "downregulation of kinase activity" EXACT [] synonym: "inhibition of kinase activity" NARROW [] synonym: "kinase inhibitor" NARROW [] is_a: GO:0042326 ! negative regulation of phosphorylation is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051348 ! negative regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016301 ! kinase activity relationship: negatively_regulates GO:0016301 ! kinase activity [Term] id: GO:0033674 name: positive regulation of kinase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:mah] subset: term_scheduled_for_obsoletion synonym: "kinase activator" NARROW [] synonym: "stimulation of kinase activity" NARROW [] synonym: "up regulation of kinase activity" EXACT [] synonym: "up-regulation of kinase activity" EXACT [] synonym: "upregulation of kinase activity" EXACT [] is_a: GO:0042327 ! positive regulation of phosphorylation is_a: GO:0043549 ! regulation of kinase activity is_a: GO:0051347 ! positive regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016301 ! kinase activity relationship: positively_regulates GO:0016301 ! kinase activity [Term] id: GO:0033750 name: ribosome localization namespace: biological_process alt_id: GO:0033753 def: "A process in which a ribosome is transported to, and/or maintained in, a specific location." [GOC:mah] synonym: "establishment of ribosome localisation" RELATED [] synonym: "establishment of ribosome localization" RELATED [] synonym: "ribosome localisation" RELATED [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005840 ! ribosome relationship: has_primary_input GO:0005840 ! ribosome [Term] id: GO:0033762 name: response to glucagon namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." [GOC:sl] synonym: "response to glucagon stimulus" EXACT [GOC:dos] is_a: GO:0043434 ! response to peptide hormone intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:5391 ! glucagon relationship: has_input CHEBI:5391 ! glucagon [Term] id: GO:0033993 name: response to lipid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." [GOC:sl] is_a: GO:0010033 ! response to organic substance intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:18059 ! lipid relationship: has_input CHEBI:18059 ! lipid [Term] id: GO:0034067 name: protein localization to Golgi apparatus namespace: biological_process alt_id: GO:0000042 alt_id: GO:0072600 def: "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." [GOC:mah] synonym: "establishment of protein localisation to Golgi" NARROW [GOC:mah] synonym: "establishment of protein localization in Golgi" NARROW [] synonym: "establishment of protein localization to Golgi" NARROW [] synonym: "establishment of protein localization to Golgi apparatus" NARROW [GOC:mah] synonym: "protein localisation in Golgi apparatus" EXACT [GOC:mah] synonym: "protein localization in Golgi apparatus" EXACT [] synonym: "protein targeting to Golgi" RELATED [] synonym: "protein-Golgi targeting" RELATED [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005794 ! Golgi apparatus relationship: has_target_end_location GO:0005794 ! Golgi apparatus created_by: mah creation_date: 2011-02-14T02:26:36Z [Term] id: GO:0034101 name: erythrocyte homeostasis namespace: biological_process def: "Any process of regulating the production and elimination of erythrocytes within an organism." [GOC:add, PMID:10694114, PMID:14754397] synonym: "RBC homeostasis" EXACT [CL:0000232] synonym: "red blood cell homeostasis" EXACT [CL:0000232] is_a: GO:0002262 ! myeloid cell homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000232 ! erythrocyte relationship: acts_on_population_of CL:0000232 ! erythrocyte [Term] id: GO:0034219 name: carbohydrate transmembrane transport namespace: biological_process def: "The process in which a carbohydrate is transported across a membrane." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "carbohydrate membrane transport" EXACT [] synonym: "transmembrane carbohydrate transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0008643 ! carbohydrate transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16646 ! carbohydrate intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0034220 name: monoatomic ion transmembrane transport namespace: biological_process alt_id: GO:0099131 def: "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "ATP hydrolysis coupled ion transmembrane transport" NARROW [] synonym: "ion membrane transport" EXACT [] synonym: "ion transmembrane transport" BROAD [] synonym: "transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0006811 ! monoatomic ion transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24867 ! monoatomic ion intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0034242 name: negative regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:mah] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion relationship: negatively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion [Term] id: GO:0034248 name: regulation of amide metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "regulation of amide metabolism" EXACT [] synonym: "regulation of cellular amide metabolic process" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043603 ! amide metabolic process relationship: regulates GO:0043603 ! amide metabolic process [Term] id: GO:0034249 name: negative regulation of amide metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "negative regulation of amide metabolism" EXACT [] synonym: "negative regulation of cellular amide metabolic process" EXACT [] is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043603 ! amide metabolic process relationship: negatively_regulates GO:0043603 ! amide metabolic process [Term] id: GO:0034250 name: positive regulation of amide metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." [GOC:mah] synonym: "positive regulation of amide metabolism" EXACT [] synonym: "positive regulation of cellular amide metabolic process" EXACT [] is_a: GO:0034248 ! regulation of amide metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043603 ! amide metabolic process relationship: positively_regulates GO:0043603 ! amide metabolic process [Term] id: GO:0034251 name: regulation of amide catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "regulation of amide breakdown" EXACT [] synonym: "regulation of amide catabolism" EXACT [] synonym: "regulation of amide degradation" EXACT [] synonym: "regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0034248 ! regulation of amide metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043605 ! amide catabolic process relationship: regulates GO:0043605 ! amide catabolic process [Term] id: GO:0034252 name: negative regulation of amide catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "negative regulation of amide breakdown" EXACT [] synonym: "negative regulation of amide catabolism" EXACT [] synonym: "negative regulation of amide degradation" RELATED [] synonym: "negative regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0034249 ! negative regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043605 ! amide catabolic process relationship: negatively_regulates GO:0043605 ! amide catabolic process [Term] id: GO:0034253 name: positive regulation of amide catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." [GOC:mah] synonym: "positive regulation of amide breakdown" EXACT [] synonym: "positive regulation of amide catabolism" EXACT [] synonym: "positive regulation of amide degradation" RELATED [] synonym: "positive regulation of cellular amide catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0034251 ! regulation of amide catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043605 ! amide catabolic process relationship: positively_regulates GO:0043605 ! amide catabolic process [Term] id: GO:0034284 name: response to monosaccharide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." [GOC:mah] synonym: "response to monosaccharide stimulus" EXACT [GOC:dos] is_a: GO:0009743 ! response to carbohydrate intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:35381 ! monosaccharide relationship: has_input CHEBI:35381 ! monosaccharide [Term] id: GO:0034329 name: cell junction assembly namespace: biological_process def: "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0030054 ! cell junction relationship: results_in_assembly_of GO:0030054 ! cell junction [Term] id: GO:0034330 name: cell junction organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl subset: goslim_generic synonym: "cell junction assembly and maintenance" EXACT [] synonym: "cell junction biogenesis" RELATED [] synonym: "cell junction organisation" EXACT [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030054 ! cell junction relationship: results_in_organization_of GO:0030054 ! cell junction [Term] id: GO:0034349 name: glial cell apoptotic process namespace: biological_process def: "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." [CL:0000125, GOC:mtg_apoptosis, GOC:sart] synonym: "apoptosis of glia" EXACT [] synonym: "apoptosis of glial cells" EXACT [] synonym: "glia apoptosis" EXACT [] synonym: "glia programmed cell death by apoptosis" EXACT [] synonym: "glial cell apoptosis" NARROW [] synonym: "glial cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of glia by apoptosis" EXACT [] synonym: "programmed cell death of glial cells by apoptosis" EXACT [] synonym: "programmed cell death, glia" EXACT [] synonym: "programmed cell death, glial cells" EXACT [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000125 ! glial cell relationship: occurs_in CL:0000125 ! glial cell [Term] id: GO:0034350 name: regulation of glial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "regulation of glial cell apoptosis" RELATED [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034349 ! glial cell apoptotic process relationship: regulates GO:0034349 ! glial cell apoptotic process [Term] id: GO:0034351 name: negative regulation of glial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "down regulation of glial cell apoptosis" EXACT [] synonym: "down-regulation of glial cell apoptosis" EXACT [] synonym: "downregulation of glial cell apoptosis" EXACT [] synonym: "inhibition of glial cell apoptosis" NARROW [] synonym: "negative regulation of glial cell apoptosis" NARROW [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043066 ! negative regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034349 ! glial cell apoptotic process relationship: negatively_regulates GO:0034349 ! glial cell apoptotic process [Term] id: GO:0034352 name: positive regulation of glial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "activation of glial cell apoptosis" NARROW [] synonym: "positive regulation of glial cell apoptosis" NARROW [] synonym: "stimulation of glial cell apoptosis" NARROW [] synonym: "up regulation of glial cell apoptosis" EXACT [] synonym: "up-regulation of glial cell apoptosis" EXACT [] synonym: "upregulation of glial cell apoptosis" EXACT [] is_a: GO:0034350 ! regulation of glial cell apoptotic process is_a: GO:0043065 ! positive regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034349 ! glial cell apoptotic process relationship: positively_regulates GO:0034349 ! glial cell apoptotic process [Term] id: GO:0034390 name: smooth muscle cell apoptotic process namespace: biological_process def: "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." [CL:0000192, GOC:BHF, GOC:mah, GOC:mtg_apoptosis, GOC:rl] synonym: "apoptosis of smooth muscle cells" EXACT [] synonym: "programmed cell death of smooth muscle cells by apoptosis" EXACT [] synonym: "programmed cell death, smooth muscle cells" EXACT [] synonym: "SMC apoptosis" EXACT [] synonym: "smooth muscle cell apoptosis" NARROW [] synonym: "smooth muscle cell programmed cell death by apoptosis" EXACT [] is_a: GO:0010657 ! muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000192 ! smooth muscle cell relationship: occurs_in CL:0000192 ! smooth muscle cell [Term] id: GO:0034391 name: regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "regulation of SMC apoptosis" EXACT [] synonym: "regulation of smooth muscle cell apoptosis" NARROW [] is_a: GO:0010660 ! regulation of muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034390 ! smooth muscle cell apoptotic process relationship: regulates GO:0034390 ! smooth muscle cell apoptotic process [Term] id: GO:0034392 name: negative regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "down regulation of smooth muscle cell apoptosis" EXACT [] synonym: "down-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "downregulation of smooth muscle cell apoptosis" EXACT [] synonym: "inhibition of smooth muscle cell apoptosis" NARROW [] synonym: "negative regulation of SMC apoptosis" EXACT [] synonym: "negative regulation of smooth muscle cell apoptosis" NARROW [] is_a: GO:0010656 ! negative regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process relationship: negatively_regulates GO:0034390 ! smooth muscle cell apoptotic process [Term] id: GO:0034393 name: positive regulation of smooth muscle cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl] synonym: "activation of smooth muscle cell apoptosis" NARROW [] synonym: "positive regulation of SMC apoptosis" EXACT [] synonym: "positive regulation of smooth muscle cell apoptosis" NARROW [] synonym: "stimulation of smooth muscle cell apoptosis" NARROW [] synonym: "up regulation of smooth muscle cell apoptosis" EXACT [] synonym: "up-regulation of smooth muscle cell apoptosis" EXACT [] synonym: "upregulation of smooth muscle cell apoptosis" EXACT [] is_a: GO:0010661 ! positive regulation of muscle cell apoptotic process is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process relationship: positively_regulates GO:0034390 ! smooth muscle cell apoptotic process [Term] id: GO:0034436 name: glycoprotein transport namespace: biological_process def: "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:BHF, GOC:mah, GOC:rl] is_a: GO:0015031 ! protein transport is_a: GO:1901264 ! carbohydrate derivative transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:17089 ! glycoprotein relationship: has_primary_input CHEBI:17089 ! glycoprotein [Term] id: GO:0034486 name: vacuolar transmembrane transport namespace: biological_process def: "The process in which a solute is transported from one side of the vacuolar membrane to the other." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "vacuolar membrane transport" EXACT [] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_across GO:0016020 ! membrane intersection_of: results_in_transport_to_from_or_in GO:0005773 ! vacuole relationship: results_in_transport_to_from_or_in GO:0005773 ! vacuole [Term] id: GO:0034487 name: vacuolar amino acid transmembrane transport namespace: biological_process def: "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "vacuolar amino acid membrane transport" EXACT [] is_a: GO:0003333 ! amino acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33709 ! amino acid intersection_of: results_in_transport_across GO:0005774 ! vacuolar membrane relationship: results_in_transport_across GO:0005774 ! vacuolar membrane [Term] id: GO:0034502 name: protein localization to chromosome namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." [GOC:mah] synonym: "condensin localization to chromosome" NARROW [] synonym: "protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005694 ! chromosome relationship: has_target_end_location GO:0005694 ! chromosome [Term] id: GO:0034504 name: protein localization to nucleus namespace: biological_process alt_id: GO:0044744 def: "A process in which a protein transports or maintains the localization of another protein to the nucleus." [GOC:ecd] synonym: "protein localisation to nucleus" EXACT [GOC:mah] synonym: "protein localization in cell nucleus" EXACT [] synonym: "protein localization in nucleus" EXACT [GOC:mah] synonym: "protein targeting to nucleus" RELATED [] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005634 ! nucleus relationship: has_target_end_location GO:0005634 ! nucleus creation_date: 2012-11-07T15:45:54Z [Term] id: GO:0034641 name: cellular nitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." [GOC:mah] subset: goslim_chembl synonym: "cellular nitrogen compound metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0034654 name: nucleobase-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid anabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid formation" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" NARROW [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_output CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0034655 name: nucleobase-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:mah] subset: goslim_chembl synonym: "nucleobase, nucleoside, nucleotide and nucleic acid breakdown" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" RELATED [GOC:dph, GOC:tb] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid catabolism" EXACT [] synonym: "nucleobase, nucleoside, nucleotide and nucleic acid degradation" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity relationship: has_primary_input CHEBI:61120 ! nucleobase-containing molecular entity [Term] id: GO:0034672 name: anterior/posterior pattern specification involved in pronephros development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mah] synonym: "anterior/posterior pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0039017 ! pattern specification involved in pronephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0048793 ! pronephros development [Term] id: GO:0034762 name: regulation of transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "regulation of membrane transport" EXACT [] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055085 ! transmembrane transport relationship: regulates GO:0055085 ! transmembrane transport [Term] id: GO:0034763 name: negative regulation of transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane transport" EXACT [] synonym: "down-regulation of transmembrane transport" EXACT [] synonym: "downregulation of transmembrane transport" EXACT [] synonym: "inhibition of transmembrane transport" NARROW [] synonym: "negative regulation of membrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055085 ! transmembrane transport relationship: negatively_regulates GO:0055085 ! transmembrane transport [Term] id: GO:0034764 name: positive regulation of transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." [GOC:mah] synonym: "activation of transmembrane transport" NARROW [] synonym: "positive regulation of membrane transport" EXACT [] synonym: "stimulation of transmembrane transport" NARROW [] synonym: "up regulation of transmembrane transport" EXACT [] synonym: "up-regulation of transmembrane transport" EXACT [] synonym: "upregulation of transmembrane transport" EXACT [] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055085 ! transmembrane transport relationship: positively_regulates GO:0055085 ! transmembrane transport [Term] id: GO:0034765 name: regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "regulation of ion membrane transport" EXACT [] synonym: "regulation of ion transmembrane transport" BROAD [] synonym: "regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0043269 ! regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034220 ! monoatomic ion transmembrane transport relationship: regulates GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0034766 name: negative regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "down regulation of transmembrane ion transport" EXACT [] synonym: "down-regulation of transmembrane ion transport" EXACT [] synonym: "downregulation of transmembrane ion transport" EXACT [] synonym: "inhibition of transmembrane ion transport" NARROW [] synonym: "negative regulation of ion membrane transport" EXACT [] synonym: "negative regulation of ion transmembrane transport" BROAD [] synonym: "negative regulation of transmembrane ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043271 ! negative regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034220 ! monoatomic ion transmembrane transport relationship: negatively_regulates GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0034767 name: positive regulation of monoatomic ion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." [GOC:mah] synonym: "activation of transmembrane ion transport" NARROW [] synonym: "positive regulation of ion membrane transport" EXACT [] synonym: "positive regulation of ion transmembrane transport" BROAD [] synonym: "positive regulation of transmembrane ion transport" EXACT [] synonym: "stimulation of transmembrane ion transport" NARROW [] synonym: "up regulation of transmembrane ion transport" EXACT [] synonym: "up-regulation of transmembrane ion transport" EXACT [] synonym: "upregulation of transmembrane ion transport" EXACT [] is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport is_a: GO:0043270 ! positive regulation of monoatomic ion transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034220 ! monoatomic ion transmembrane transport relationship: positively_regulates GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0034769 name: basement membrane disassembly namespace: biological_process alt_id: GO:0060881 def: "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." [GOC:sart, PMID:17301221] comment: Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer. synonym: "basal lamina disassembly" RELATED [] is_a: GO:0022617 ! extracellular matrix disassembly is_a: GO:0071711 ! basement membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005604 ! basement membrane relationship: results_in_disassembly_of GO:0005604 ! basement membrane created_by: dph creation_date: 2009-08-13T11:27:24Z [Term] id: GO:0035019 name: somatic stem cell population maintenance namespace: biological_process def: "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." [GOC:bf, ISBN:0582227089] is_a: GO:0019827 ! stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000723 ! somatic stem cell relationship: acts_on_population_of CL:0000723 ! somatic stem cell [Term] id: GO:0035039 name: male pronucleus assembly namespace: biological_process def: "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." [GOC:bf, PMID:11735001] synonym: "male pronucleus formation" RELATED [GOC:dph] is_a: GO:0006997 ! nucleus organization is_a: GO:0022414 ! reproductive process is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0001940 ! male pronucleus relationship: part_of GO:0007338 ! single fertilization relationship: results_in_assembly_of GO:0001940 ! male pronucleus [Term] id: GO:0035040 name: sperm nuclear envelope removal namespace: biological_process def: "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." [GOC:bf, PMID:11735001] is_a: GO:0022414 ! reproductive process is_a: GO:0051081 ! nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: occurs_in CL:0000019 ! sperm relationship: occurs_in CL:0000019 ! sperm relationship: part_of GO:0035039 ! male pronucleus assembly [Term] id: GO:0035045 name: sperm plasma membrane disassembly namespace: biological_process def: "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." [GOC:bf, ISBN:0879694238] synonym: "sperm plasma membrane breakdown" EXACT [] synonym: "sperm plasma membrane catabolism" EXACT [] synonym: "sperm plasma membrane degradation" EXACT [] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030397 ! membrane disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0097524 ! sperm plasma membrane relationship: part_of GO:0007338 ! single fertilization relationship: results_in_disassembly_of GO:0097524 ! sperm plasma membrane [Term] id: GO:0035050 name: embryonic heart tube development namespace: biological_process def: "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." [GOC:go_curators] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004141 ! heart tube relationship: part_of GO:0007507 ! heart development relationship: part_of GO:0048568 ! embryonic organ development relationship: results_in_development_of UBERON:0004141 ! heart tube [Term] id: GO:0035051 name: cardiocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." [GOC:bf] synonym: "cardiac cell differentiation" EXACT [] synonym: "heart cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002494 ! cardiocyte relationship: part_of GO:0007507 ! heart development relationship: results_in_acquisition_of_features_of CL:0002494 ! cardiocyte [Term] id: GO:0035082 name: axoneme assembly namespace: biological_process alt_id: GO:0035083 alt_id: GO:0035084 def: "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." [GOC:bf, GOC:cilia, GOC:jl, ISBN:0815316194] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. synonym: "axoneme biogenesis" RELATED [GOC:mah] synonym: "ciliary axoneme assembly" EXACT [] synonym: "cilium axoneme assembly" EXACT [] synonym: "cilium axoneme biogenesis" RELATED [GOC:mah] synonym: "flagellar axoneme assembly" EXACT [] synonym: "flagellum axoneme assembly" EXACT [] is_a: GO:0001578 ! microtubule bundle formation is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005930 ! axoneme relationship: part_of GO:0060271 ! cilium assembly relationship: results_in_assembly_of GO:0005930 ! axoneme [Term] id: GO:0035107 name: appendage morphogenesis namespace: biological_process def: "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [ISBN:0582227089] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000026 ! appendage relationship: part_of GO:0048736 ! appendage development relationship: results_in_morphogenesis_of UBERON:0000026 ! appendage [Term] id: GO:0035108 name: limb morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping." [UBERON:0002101] synonym: "limb bud morphogenesis" NARROW [GOC:dph] is_a: GO:0035107 ! appendage morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002101 ! limb relationship: part_of GO:0060173 ! limb development relationship: results_in_morphogenesis_of UBERON:0002101 ! limb [Term] id: GO:0035112 name: genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." [GOC:bf] synonym: "genital morphogenesis" RELATED [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000990 ! reproductive system relationship: part_of GO:0048806 ! genitalia development relationship: results_in_morphogenesis_of UBERON:0000990 ! reproductive system [Term] id: GO:0035136 name: forelimb morphogenesis namespace: biological_process alt_id: GO:0035140 def: "The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human." [GOC:go_curators] synonym: "arm morphogenesis" NARROW [GOC:bf, GOC:cjm] is_a: GO:0035108 ! limb morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002102 ! forelimb relationship: results_in_morphogenesis_of UBERON:0002102 ! forelimb [Term] id: GO:0035137 name: hindlimb morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the hindlimb are generated and organized." [GOC:go_curators] is_a: GO:0035108 ! limb morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002103 ! hindlimb relationship: results_in_morphogenesis_of UBERON:0002103 ! hindlimb [Term] id: GO:0035148 name: tube formation namespace: biological_process def: "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." [GOC:bf] synonym: "lumen formation in an anatomical structure" RELATED [GOC:dph, GOC:mah] synonym: "tube lumen formation" EXACT [GOC:dph, GOC:mah] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000025 ! tube relationship: part_of GO:0035239 ! tube morphogenesis relationship: results_in_formation_of UBERON:0000025 ! tube [Term] id: GO:0035190 name: syncytial nuclear migration namespace: biological_process def: "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." [GOC:bf, ISBN:0879694238, PMID:8314839] is_a: GO:0007097 ! nuclear migration intersection_of: GO:0007097 ! nuclear migration intersection_of: occurs_in CL:0000228 ! multinucleate cell relationship: occurs_in CL:0000228 ! multinucleate cell relationship: part_of GO:0001700 ! embryonic development via the syncytial blastoderm [Term] id: GO:0035234 name: ectopic germ cell programmed cell death namespace: biological_process def: "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." [PMID:12814944] synonym: "programmed cell death of ectopic germ cells" EXACT [] synonym: "programmed cell death, ectopic germ cells" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0010623 ! programmed cell death involved in cell development intersection_of: GO:0012501 ! programmed cell death intersection_of: occurs_in CL:0000586 ! germ cell relationship: occurs_in CL:0000586 ! germ cell [Term] id: GO:0035239 name: tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:bf, PMID:14624839] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000025 ! tube relationship: part_of GO:0035295 ! tube development relationship: results_in_morphogenesis_of UBERON:0000025 ! tube [Term] id: GO:0035260 name: internal genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [http://www.ndif.org/Terms/genitalia.html] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004175 ! internal genitalia relationship: results_in_morphogenesis_of UBERON:0004175 ! internal genitalia [Term] id: GO:0035261 name: external genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [http://www.ndif.org/Terms/genitalia.html] is_a: GO:0035112 ! genitalia morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004176 ! external genitalia relationship: results_in_morphogenesis_of UBERON:0004176 ! external genitalia [Term] id: GO:0035262 name: gonad morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." [ISBN:0198612001] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000991 ! gonad relationship: part_of GO:0008406 ! gonad development relationship: results_in_morphogenesis_of UBERON:0000991 ! gonad [Term] id: GO:0035264 name: multicellular organism growth namespace: biological_process def: "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." [GOC:bf, GOC:curators, GOC:dph, GOC:tb] synonym: "body growth" RELATED [] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0000468 ! multicellular organism relationship: results_in_growth_of UBERON:0000468 ! multicellular organism [Term] id: GO:0035265 name: organ growth namespace: biological_process def: "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." [GOC:bf, ISBN:0471245208, ISBN:0721662544] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0000062 ! organ relationship: results_in_growth_of UBERON:0000062 ! organ [Term] id: GO:0035270 name: endocrine system development namespace: biological_process def: "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." [GOC:bf, Wikipedia:Development_of_the_endocrine_system] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000949 ! endocrine system relationship: results_in_development_of UBERON:0000949 ! endocrine system [Term] id: GO:0035272 name: exocrine system development namespace: biological_process def: "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." [GOC:bf, Wikipedia:Exocrine_gland] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002330 ! exocrine system relationship: results_in_development_of UBERON:0002330 ! exocrine system [Term] id: GO:0035282 name: segmentation namespace: biological_process def: "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." [PMID:10611687, PMID:9706689] xref: Wikipedia:Segmentation_(biology) is_a: GO:0003002 ! regionalization [Term] id: GO:0035290 name: trunk segmentation namespace: biological_process def: "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." [PMID:1360402] is_a: GO:0035282 ! segmentation relationship: part_of GO:0007350 ! blastoderm segmentation [Term] id: GO:0035295 name: tube development namespace: biological_process def: "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." [PMID:12526790] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000025 ! tube relationship: part_of GO:0007275 ! multicellular organism development relationship: results_in_development_of UBERON:0000025 ! tube [Term] id: GO:0035322 name: mesenchymal cell migration involved in limb bud formation namespace: biological_process def: "The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud." [GOC:dgh] is_a: GO:0090497 ! mesenchymal cell migration intersection_of: GO:0090497 ! mesenchymal cell migration intersection_of: part_of GO:0060174 ! limb bud formation relationship: part_of GO:0090496 ! mesenchyme migration involved in limb bud formation created_by: bf creation_date: 2010-02-24T02:05:14Z [Term] id: GO:0035372 name: protein localization to microtubule namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a microtubule." [GOC:bf, GOC:lb] synonym: "protein localisation to microtubule" EXACT [GOC:mah] is_a: GO:0072698 ! protein localization to microtubule cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005874 ! microtubule relationship: has_target_end_location GO:0005874 ! microtubule created_by: bf creation_date: 2010-03-11T11:00:56Z [Term] id: GO:0035418 name: protein localization to synapse namespace: biological_process def: "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:bf] synonym: "protein localisation to synapse" EXACT [GOC:mah] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0045202 ! synapse relationship: has_target_end_location GO:0045202 ! synapse created_by: bf creation_date: 2010-03-29T10:58:53Z [Term] id: GO:0035433 name: acetate transmembrane transport namespace: biological_process def: "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "acetate membrane transport" EXACT [] is_a: GO:0006846 ! acetate transport is_a: GO:1905039 ! carboxylic acid transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:30089 ! acetate intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: bf creation_date: 2010-04-08T10:59:01Z [Term] id: GO:0035435 name: phosphate ion transmembrane transport namespace: biological_process def: "The process in which a phosphate is transported across a membrane." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "phosphate ion membrane transport" EXACT [] is_a: GO:0006817 ! phosphate ion transport is_a: GO:0098661 ! inorganic anion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:35780 ! phosphate ion intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: bf creation_date: 2010-04-08T11:24:06Z [Term] id: GO:0035441 name: cell migration involved in vasculogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." [GOC:dgh] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001570 ! vasculogenesis relationship: part_of GO:0001570 ! vasculogenesis created_by: bf creation_date: 2010-04-09T03:53:01Z [Term] id: GO:0035556 name: intracellular signal transduction namespace: biological_process alt_id: GO:0007242 alt_id: GO:0007243 alt_id: GO:0023013 alt_id: GO:0023034 def: "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782] subset: goslim_drosophila synonym: "intracellular protein kinase cascade" NARROW [GOC:signaling] synonym: "intracellular signal transduction pathway" NARROW [] synonym: "intracellular signaling cascade" RELATED [GOC:signaling] synonym: "intracellular signaling chain" EXACT [ISBN:3527303782] synonym: "intracellular signaling pathway" RELATED [] synonym: "protein kinase cascade" NARROW [GOC:signaling] synonym: "signal transduction via intracellular signaling cascade" RELATED [] synonym: "signal transmission via intracellular cascade" NARROW [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: occurs_in GO:0005622 ! intracellular anatomical structure created_by: bf creation_date: 2010-05-14T01:14:37Z [Term] id: GO:0035592 name: establishment of protein localization to extracellular region namespace: biological_process def: "The directed movement of a protein to a specific location within the extracellular region." [GOC:bf, GOC:BHF] synonym: "establishment of protein localisation in extracellular region" EXACT [GOC:mah] synonym: "establishment of protein localization in extracellular region" EXACT [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0071692 ! protein localization to extracellular region intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005576 ! extracellular region created_by: bf creation_date: 2010-11-09T10:25:08Z [Term] id: GO:0035622 name: intrahepatic bile duct development namespace: biological_process def: "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." [GOC:bf, PMID:20614624] synonym: "IHBD development" EXACT [PMID:20614624] synonym: "intrahepatic biliary duct development" EXACT [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003704 ! intrahepatic bile duct relationship: part_of GO:0001889 ! liver development relationship: results_in_development_of UBERON:0003704 ! intrahepatic bile duct created_by: bf creation_date: 2010-12-08T04:10:50Z [Term] id: GO:0035628 name: cystic duct development namespace: biological_process def: "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct." [PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001152 ! cystic duct relationship: results_in_development_of UBERON:0001152 ! cystic duct created_by: bf creation_date: 2010-12-10T01:24:28Z [Term] id: GO:0035645 name: enteric smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." [CL:0002504, GOC:BHF] synonym: "intestinal smooth muscle cell differentiation" EXACT [CL:0002504] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002504 ! enteric smooth muscle cell relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_acquisition_of_features_of CL:0002504 ! enteric smooth muscle cell created_by: bf creation_date: 2011-01-21T02:58:58Z [Term] id: GO:0035701 name: hematopoietic stem cell migration namespace: biological_process def: "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." [CL:0000037, GOC:BHF, PMID:20234092] synonym: "hemopoietic stem cell migration" EXACT [CL:0000037] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000037 ! hematopoietic stem cell relationship: results_in_movement_of CL:0000037 ! hematopoietic stem cell created_by: bf creation_date: 2011-02-28T03:20:36Z [Term] id: GO:0035725 name: sodium ion transmembrane transport namespace: biological_process def: "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "sodium ion membrane transport" EXACT [] is_a: GO:0006814 ! sodium ion transport is_a: GO:0098655 ! monoatomic cation transmembrane transport is_a: GO:0098662 ! inorganic cation transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: has_primary_input CHEBI:29101 ! sodium(1+) created_by: bf creation_date: 2011-03-10T02:52:36Z [Term] id: GO:0035735 name: intraciliary transport involved in cilium assembly namespace: biological_process def: "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." [GOC:bf, GOC:cilia, Reactome:R-HSA-5620924.2] synonym: "intraciliary transport involved in cilium morphogenesis" RELATED [] synonym: "intraflagellar transport" BROAD [] synonym: "intraflagellar transport involved in cilium morphogenesis" RELATED [] xref: Reactome:R-HSA-5620924.2 is_a: GO:0042073 ! intraciliary transport intersection_of: GO:0042073 ! intraciliary transport intersection_of: part_of GO:0060271 ! cilium assembly relationship: part_of GO:0060271 ! cilium assembly created_by: bf creation_date: 2011-03-17T10:55:42Z [Term] id: GO:0035736 name: cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." [GOC:bf, GOC:sart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001745 ! compound eye morphogenesis relationship: part_of GO:0001745 ! compound eye morphogenesis created_by: bf creation_date: 2011-03-17T10:57:03Z [Term] id: GO:0035778 name: pronephric nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:yaf, PMID:18787069] is_a: GO:0039014 ! cell differentiation involved in pronephros development is_a: GO:0072160 ! nephron tubule epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000090 ! pronephric nephron tubule epithelial cell relationship: part_of GO:0039020 ! pronephric nephron tubule development relationship: results_in_acquisition_of_features_of CL:1000090 ! pronephric nephron tubule epithelial cell created_by: bf creation_date: 2011-04-04T11:07:47Z [Term] id: GO:0035779 name: angioblast cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." [CL:0000566, GOC:yaf] synonym: "angioblastic mesenchymal cell differentiation" EXACT [CL:0000566] is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000566 ! angioblastic mesenchymal cell relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_acquisition_of_features_of CL:0000566 ! angioblastic mesenchymal cell created_by: bf creation_date: 2011-04-04T11:10:38Z [Term] id: GO:0035787 name: cell migration involved in kidney development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: bf creation_date: 2011-04-06T10:39:52Z [Term] id: GO:0035788 name: cell migration involved in metanephros development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf] synonym: "cell migration involved in metanephric kidney development" EXACT [GOC:bf] is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: bf creation_date: 2011-04-06T10:42:21Z [Term] id: GO:0035799 name: ureter maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:17881463] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0000056 ! ureter relationship: part_of GO:0072189 ! ureter development relationship: results_in_maturation_of UBERON:0000056 ! ureter created_by: bf creation_date: 2011-04-14T01:13:39Z [Term] id: GO:0035805 name: egg coat namespace: cellular_component def: "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." [PMID:16944418, PMID:17163408] synonym: "vitelline membrane" NARROW [PMID:16944418, PMID:17163408] synonym: "zona pellucida" NARROW [PMID:16944418, PMID:17163408] is_a: GO:0031012 ! extracellular matrix intersection_of: GO:0031012 ! extracellular matrix intersection_of: part_of CL:0000025 ! egg cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of CL:0000025 ! egg cell created_by: bf creation_date: 2011-04-19T02:07:23Z [Term] id: GO:0035809 name: regulation of urine volume namespace: biological_process def: "Any process that modulates the amount of urine excreted from the body over a unit of time." [GOC:mtg_25march11, GOC:yaf] synonym: "regulation of urinary volume" EXACT [] synonym: "regulation of urine flow" EXACT [] is_a: GO:0003014 ! renal system process is_a: GO:0050878 ! regulation of body fluid levels created_by: bf creation_date: 2011-04-20T01:17:38Z [Term] id: GO:0035834 name: indole alkaloid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid metabolism" EXACT [GOC:bf] is_a: GO:0009820 ! alkaloid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:38958 ! indole alkaloid relationship: has_primary_input_or_output CHEBI:38958 ! indole alkaloid created_by: bf creation_date: 2011-05-04T03:17:44Z [Term] id: GO:0035835 name: indole alkaloid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." [GOC:yaf] synonym: "indole alkaloid anabolism" EXACT [GOC:bf] synonym: "indole alkaloid biosynthesis" EXACT [GOC:bf] synonym: "indole alkaloid formation" EXACT [GOC:bf] synonym: "indole alkaloid synthesis" EXACT [GOC:bf] is_a: GO:0009821 ! alkaloid biosynthetic process is_a: GO:0035834 ! indole alkaloid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:38958 ! indole alkaloid relationship: has_primary_output CHEBI:38958 ! indole alkaloid created_by: bf creation_date: 2011-05-04T03:18:31Z [Term] id: GO:0035844 name: cloaca development namespace: biological_process def: "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." [GOC:dgh, ISBN:0582227089] synonym: "cloacal development" EXACT [GOC:bf] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000162 ! cloaca relationship: part_of GO:0001655 ! urogenital system development relationship: part_of GO:0048546 ! digestive tract morphogenesis relationship: results_in_development_of UBERON:0000162 ! cloaca created_by: bf creation_date: 2011-05-06T01:54:35Z [Term] id: GO:0035846 name: oviduct epithelium development namespace: biological_process def: "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." [GOC:yaf, http://www.thefreedictionary.com/oviduct] synonym: "fallopian tube epithelium development" NARROW [GOC:yaf] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004804 ! oviduct epithelium relationship: part_of GO:0060066 ! oviduct development relationship: results_in_development_of UBERON:0004804 ! oviduct epithelium created_by: bf creation_date: 2011-05-10T10:53:05Z [Term] id: GO:0035847 name: uterine epithelium development namespace: biological_process def: "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:bf, GOC:yaf] synonym: "uterus epithelial development" EXACT [GOC:yaf] is_a: GO:0035846 ! oviduct epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006955 ! uterine epithelium relationship: part_of GO:0060065 ! uterus development relationship: results_in_development_of UBERON:0006955 ! uterine epithelium created_by: bf creation_date: 2011-05-10T10:57:45Z [Term] id: GO:0035848 name: oviduct morphogenesis namespace: biological_process def: "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:yaf, http://www.thefreedictionary.com/oviduct] synonym: "fallopian tube morphogenesis" NARROW [GOC:yaf] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000993 ! oviduct relationship: part_of GO:0060066 ! oviduct development relationship: results_in_morphogenesis_of UBERON:0000993 ! oviduct created_by: bf creation_date: 2011-05-10T11:01:20Z [Term] id: GO:0035850 name: epithelial cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:bf, GOC:mtg_kidney_jan10, GOC:yaf, PMID:16216236] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: part_of GO:0001822 ! kidney development created_by: bf creation_date: 2011-05-11T11:34:21Z [Term] id: GO:0035855 name: megakaryocyte development namespace: biological_process def: "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." [CL:0000556, GOC:BHF, GOC:vk] synonym: "megakaryocyte cell development" EXACT [GOC:bf] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0000556 ! megakaryocyte relationship: part_of GO:0030219 ! megakaryocyte differentiation relationship: results_in_development_of CL:0000556 ! megakaryocyte created_by: bf creation_date: 2011-05-13T01:28:06Z [Term] id: GO:0035869 name: ciliary transition zone namespace: cellular_component def: "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." [GOC:cilia, GOC:kmv, PMID:21422230] comment: Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone. synonym: "cilial transition zone" EXACT [] synonym: "cilium transition zone" EXACT [] synonym: "connecting cilium" RELATED [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0005929 ! cilium created_by: bf creation_date: 2011-05-25T03:09:58Z [Term] id: GO:0035878 name: nail development namespace: biological_process def: "The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it." [GOC:bf, ISBN:0323025781, UBERON:0001705, Wikipedia:Nail_(anatomy)] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001705 ! nail relationship: part_of GO:0060173 ! limb development relationship: results_in_development_of UBERON:0001705 ! nail created_by: bf creation_date: 2011-05-31T02:30:34Z [Term] id: GO:0035883 name: enteroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." [CL:0000164, GOC:bf] is_a: GO:0002067 ! glandular epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000164 ! enteroendocrine cell relationship: results_in_acquisition_of_features_of CL:0000164 ! enteroendocrine cell created_by: bf creation_date: 2011-06-06T11:48:51Z [Term] id: GO:0035886 name: vascular associated smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." [GOC:sl, PMID:16151017, PMID:18267954] synonym: "vascular smooth muscle cell differentiation" EXACT [] synonym: "VSMC differentiation" EXACT [PMID:16151017] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000359 ! vascular associated smooth muscle cell relationship: part_of GO:0001944 ! vasculature development relationship: results_in_acquisition_of_features_of CL:0000359 ! vascular associated smooth muscle cell created_by: bf creation_date: 2011-06-08T11:23:52Z [Term] id: GO:0035887 name: aortic smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." [GOC:sl] is_a: GO:0035886 ! vascular associated smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002539 ! aortic smooth muscle cell relationship: results_in_acquisition_of_features_of CL:0002539 ! aortic smooth muscle cell created_by: bf creation_date: 2011-06-08T11:34:26Z [Term] id: GO:0035904 name: aorta development namespace: biological_process def: "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0060840 ! artery development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000947 ! aorta relationship: results_in_development_of UBERON:0000947 ! aorta created_by: bf creation_date: 2011-06-24T11:00:07Z [Term] id: GO:0035905 name: ascending aorta development namespace: biological_process def: "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001496 ! ascending aorta relationship: part_of GO:0035904 ! aorta development relationship: results_in_development_of UBERON:0001496 ! ascending aorta created_by: bf creation_date: 2011-06-24T11:02:01Z [Term] id: GO:0035906 name: descending aorta development namespace: biological_process def: "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001514 ! descending aorta relationship: part_of GO:0035904 ! aorta development relationship: results_in_development_of UBERON:0001514 ! descending aorta created_by: bf creation_date: 2011-06-24T11:05:22Z [Term] id: GO:0035907 name: dorsal aorta development namespace: biological_process def: "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035904 ! aorta development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005805 ! dorsal aorta relationship: results_in_development_of UBERON:0005805 ! dorsal aorta created_by: bf creation_date: 2011-06-24T11:07:01Z [Term] id: GO:0035909 name: aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, MA:0000062, UBERON:0000947, Wikipedia:Aorta] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000947 ! aorta relationship: part_of GO:0035904 ! aorta development relationship: results_in_morphogenesis_of UBERON:0000947 ! aorta created_by: bf creation_date: 2011-06-24T11:11:11Z [Term] id: GO:0035910 name: ascending aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002570, UBERON:0001496, Wikipedia:Ascending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001496 ! ascending aorta relationship: part_of GO:0035905 ! ascending aorta development relationship: part_of GO:0035909 ! aorta morphogenesis relationship: results_in_morphogenesis_of UBERON:0001496 ! ascending aorta created_by: bf creation_date: 2011-06-24T11:14:52Z [Term] id: GO:0035911 name: descending aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." [GOC:bf, GOC:dgh, MA:0002571, UBERON:0001514, Wikipedia:Descending_aorta] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001514 ! descending aorta relationship: part_of GO:0035906 ! descending aorta development relationship: part_of GO:0035909 ! aorta morphogenesis relationship: results_in_morphogenesis_of UBERON:0001514 ! descending aorta created_by: bf creation_date: 2011-06-24T11:19:24Z [Term] id: GO:0035912 name: dorsal aorta morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GOC:bf, GOC:dgh, UBERON:0005805, Wikipedia:Aorta, ZFA:0000014] is_a: GO:0035909 ! aorta morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005805 ! dorsal aorta relationship: part_of GO:0035907 ! dorsal aorta development relationship: results_in_morphogenesis_of UBERON:0005805 ! dorsal aorta created_by: bf creation_date: 2011-06-24T11:22:14Z [Term] id: GO:0035914 name: skeletal muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." [CL:0000188, GOC:BHF, GOC:vk] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000188 ! cell of skeletal muscle relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: results_in_acquisition_of_features_of CL:0000188 ! cell of skeletal muscle created_by: bf creation_date: 2011-06-24T02:36:19Z [Term] id: GO:0035929 name: steroid hormone secretion namespace: biological_process def: "The regulated release of any steroid that acts as a hormone into the circulatory system." [GOC:sl] is_a: GO:0060986 ! endocrine hormone secretion is_a: GO:0140353 ! lipid export from cell intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:26764 ! steroid hormone relationship: has_primary_input CHEBI:26764 ! steroid hormone created_by: bf creation_date: 2011-07-20T01:01:00Z [Term] id: GO:0035935 name: androgen secretion namespace: biological_process def: "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." [GOC:sl] is_a: GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-20T01:11:31Z [Term] id: GO:0035981 name: tongue muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell." [CL:0002673, GOC:yaf, PMID:3393851] is_a: GO:0098528 ! skeletal muscle fiber differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002673 ! tongue muscle cell relationship: results_in_acquisition_of_features_of CL:0002673 ! tongue muscle cell created_by: bf creation_date: 2011-08-22T01:35:16Z [Term] id: GO:0035987 name: endodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." [CL:0000223, GOC:yaf, PMID:17624332] synonym: "endoderm cell differentiation" EXACT [CL:0000223] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000223 ! endodermal cell relationship: part_of GO:0001706 ! endoderm formation relationship: results_in_acquisition_of_features_of CL:0000223 ! endodermal cell created_by: bf creation_date: 2011-08-25T04:50:36Z [Term] id: GO:0035989 name: tendon development namespace: biological_process def: "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." [GOC:yaf, PMID:21412429, UBERON:0000043] synonym: "sinew development" RELATED [UBERON:0000043] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000043 ! tendon relationship: results_in_development_of UBERON:0000043 ! tendon created_by: bf creation_date: 2011-08-26T04:14:30Z [Term] id: GO:0035992 name: tendon formation namespace: biological_process def: "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." [GOC:yaf, PMID:17567668, UBERON:0000043] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000043 ! tendon relationship: part_of GO:0035989 ! tendon development relationship: results_in_formation_of UBERON:0000043 ! tendon created_by: bf creation_date: 2011-08-30T01:35:10Z [Term] id: GO:0035993 name: deltoid tuberosity development namespace: biological_process def: "The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase." [GOC:yaf, PMID:17567668, UBERON:0002498, Wikipedia:Deltoid_tuberosity] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002498 ! deltopectoral crest relationship: part_of GO:0060173 ! limb development relationship: part_of GO:0060348 ! bone development relationship: results_in_development_of UBERON:0002498 ! deltopectoral crest created_by: bf creation_date: 2011-08-30T01:46:53Z [Term] id: GO:0036022 name: limb joint morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner." [GOC:bf] synonym: "knee morphogenesis" NARROW [GOC:bf] synonym: "leg joint morphogenesis" NARROW [GOC:bf] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003657 ! limb joint relationship: part_of GO:0035108 ! limb morphogenesis relationship: results_in_morphogenesis_of UBERON:0003657 ! limb joint created_by: bf creation_date: 2011-10-13T04:52:59Z [Term] id: GO:0036072 name: direct ossification namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." [GO_REF:0000034] is_a: GO:0001503 ! ossification created_by: bf creation_date: 2011-12-19T01:47:22Z [Term] id: GO:0036093 name: germ cell proliferation namespace: biological_process def: "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." [CL:0000586, GOC:kmv] is_a: GO:0008283 ! cell population proliferation is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000586 ! germ cell relationship: acts_on_population_of CL:0000586 ! germ cell relationship: part_of GO:0007276 ! gamete generation created_by: bf creation_date: 2012-01-17T04:06:27Z [Term] id: GO:0036099 name: female germ-line stem cell population maintenance namespace: biological_process def: "The process by which an organism or tissue maintains a population of female germ-line stem cells." [GOC:sart] is_a: GO:0030718 ! germ-line stem cell population maintenance intersection_of: GO:0098727 ! maintenance of cell number intersection_of: acts_on_population_of CL:0000022 ! female germ line stem cell relationship: acts_on_population_of CL:0000022 ! female germ line stem cell created_by: bf creation_date: 2012-01-26T01:58:10Z [Term] id: GO:0036135 name: Schwann cell migration namespace: biological_process def: "The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function." [CL:0002573, PMID:20335460] is_a: GO:0008347 ! glial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0002573 ! Schwann cell relationship: results_in_movement_of CL:0002573 ! Schwann cell created_by: bf creation_date: 2012-03-06T10:44:39Z [Term] id: GO:0036145 name: dendritic cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [CL:0000451, GOC:uh, PMID:12570827, PMID:19176316] synonym: "DC homeostasis" RELATED [PMID:19176316] is_a: GO:0001776 ! leukocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000451 ! dendritic cell relationship: acts_on_population_of CL:0000451 ! dendritic cell created_by: bf creation_date: 2012-03-12T11:05:36Z [Term] id: GO:0036194 name: muscle cell projection namespace: cellular_component def: "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] synonym: "muscle arm" NARROW [GOC:kmv] synonym: "myocyte projection" EXACT [CL:0000187] synonym: "myopodia" NARROW [GOC:kmv] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000187 ! muscle cell relationship: part_of CL:0000187 ! muscle cell created_by: bf creation_date: 2012-04-20T10:20:47Z [Term] id: GO:0036195 name: muscle cell projection membrane namespace: cellular_component def: "The portion of the plasma membrane surrounding a muscle cell projection." [CL:0000187, GOC:kmv, PMID:15930100, PMID:22464329] is_a: GO:0031253 ! cell projection membrane intersection_of: GO:0031253 ! cell projection membrane intersection_of: part_of GO:0036194 ! muscle cell projection relationship: part_of GO:0036194 ! muscle cell projection created_by: bf creation_date: 2012-04-20T10:21:51Z [Term] id: GO:0036304 name: umbilical cord morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:gr, PMID:15107403] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002331 ! umbilical cord relationship: part_of GO:0061027 ! umbilical cord development relationship: results_in_morphogenesis_of UBERON:0002331 ! umbilical cord created_by: bf creation_date: 2012-08-08T10:12:11Z [Term] id: GO:0036305 name: ameloblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ." [CL:0000059] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000059 ! ameloblast relationship: results_in_acquisition_of_features_of CL:0000059 ! ameloblast created_by: bf creation_date: 2012-08-08T13:49:15Z [Term] id: GO:0036333 name: hepatocyte homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." [CL:0000182, GOC:nhn, PMID:19878874] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000182 ! hepatocyte relationship: acts_on_population_of CL:0000182 ! hepatocyte created_by: bf creation_date: 2012-09-05T10:17:07Z [Term] id: GO:0036334 name: epidermal stem cell homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." [CL:1000428, GOC:nhn, PMID:17666529] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:1000428 ! stem cell of epidermis relationship: acts_on_population_of CL:1000428 ! stem cell of epidermis created_by: bf creation_date: 2012-09-05T10:21:23Z [Term] id: GO:0036336 name: dendritic cell migration namespace: biological_process def: "The movement of a dendritic cell within or between different tissues and organs of the body." [CL:0000451, GOC:nhn, PMID:19339990] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000451 ! dendritic cell relationship: results_in_movement_of CL:0000451 ! dendritic cell created_by: bf creation_date: 2012-09-05T10:24:46Z [Term] id: GO:0036342 name: post-anal tail morphogenesis namespace: biological_process def: "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance." [GOC:bf, GOC:kmv, Wikipedia:Chordate] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007812 ! post-anal tail relationship: in_taxon NCBITaxon:7711 {all_only="true"} ! Chordata relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: results_in_morphogenesis_of UBERON:0007812 ! post-anal tail created_by: bf creation_date: 2012-09-11T13:54:49Z [Term] id: GO:0036477 name: somatodendritic compartment namespace: cellular_component def: "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." [GOC:pad, GOC:PARL] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000540 ! neuron created_by: bf creation_date: 2014-07-24T10:06:19Z [Term] id: GO:0036484 name: trunk neural crest cell migration namespace: biological_process def: "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." [GOC:bf, GOC:mat, GOC:PARL, PMID:2387238] synonym: "trunk NCC migration" EXACT [PMID:2387238] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000011 ! migratory trunk neural crest cell relationship: part_of GO:0035290 ! trunk segmentation relationship: results_in_movement_of CL:0000011 ! migratory trunk neural crest cell created_by: bf creation_date: 2014-08-26T15:27:44Z [Term] id: GO:0036504 name: Golgi membrane fusion namespace: biological_process def: "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." [GOC:bf, GOC:PARL, PMID:12473691] synonym: "Golgi apparatus membrane fusion" EXACT [] synonym: "membrane fusion involved in Golgi reassembly" EXACT [GOC:bf] synonym: "post-mitotic fusion of Golgi membranes" EXACT [PMID:10811609] is_a: GO:0090174 ! organelle membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: results_in_fusion_of GO:0000139 ! Golgi membrane relationship: part_of GO:0090168 ! Golgi reassembly relationship: results_in_fusion_of GO:0000139 ! Golgi membrane created_by: bf creation_date: 2015-05-21T10:05:06Z [Term] id: GO:0039006 name: pronephric nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros." [GOC:mtg_kidney_jan10] synonym: "pronephric tubule formation" EXACT [GOC:mtg_kidney_jan10] synonym: "pronephros tubule formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of GO:0039008 ! pronephric nephron tubule morphogenesis relationship: part_of GO:0072116 ! pronephros formation relationship: results_in_formation_of UBERON:0005310 ! pronephric nephron tubule created_by: bf creation_date: 2010-07-02T09:37:27Z [Term] id: GO:0039007 name: pronephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005309 ! pronephric nephron relationship: part_of GO:0039019 ! pronephric nephron development relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: results_in_morphogenesis_of UBERON:0005309 ! pronephric nephron created_by: bf creation_date: 2010-07-02T09:38:53Z [Term] id: GO:0039008 name: pronephric nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron." [GOC:mtg_kidney_jan10, ZFA:00001558] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of GO:0039007 ! pronephric nephron morphogenesis relationship: part_of GO:0039020 ! pronephric nephron tubule development relationship: results_in_morphogenesis_of UBERON:0005310 ! pronephric nephron tubule created_by: bf creation_date: 2010-07-02T09:45:55Z [Term] id: GO:0039014 name: cell differentiation involved in pronephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "cell differentiation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T09:59:25Z [Term] id: GO:0039015 name: cell proliferation involved in pronephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros." [GOC:mtg_kidney_jan10] synonym: "cell proliferation involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:01:49Z [Term] id: GO:0039016 name: cell-cell signaling involved in pronephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signaling involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in pronephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:03:16Z [Term] id: GO:0039017 name: pattern specification involved in pronephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "pattern specification involved in pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0048793 ! pronephros development relationship: part_of GO:0048793 ! pronephros development created_by: bf creation_date: 2010-07-02T10:04:39Z [Term] id: GO:0039019 name: pronephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros." [GOC:mtg_kidney_jan10, XAO:00002785] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005309 ! pronephric nephron relationship: part_of GO:0048793 ! pronephros development relationship: results_in_development_of UBERON:0005309 ! pronephric nephron created_by: bf creation_date: 2010-07-02T10:10:20Z [Term] id: GO:0039020 name: pronephric nephron tubule development namespace: biological_process def: "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct." [GOC:mtg_kidney_jan10, PMID:19909807, PMID:9268568] is_a: GO:0072080 ! nephron tubule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005310 ! pronephric nephron tubule relationship: part_of GO:0039019 ! pronephric nephron development relationship: results_in_development_of UBERON:0005310 ! pronephric nephron tubule created_by: bf creation_date: 2010-07-02T10:11:36Z [Term] id: GO:0039022 name: pronephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney." [GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003060 ! pronephric duct relationship: part_of GO:0048793 ! pronephros development relationship: results_in_development_of UBERON:0003060 ! pronephric duct created_by: bf creation_date: 2010-07-02T10:15:03Z [Term] id: GO:0039023 name: pronephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney." [GOC:mtg_kidney_jan10, XAO:0000063, ZFA:0000150] is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003060 ! pronephric duct relationship: part_of GO:0039022 ! pronephric duct development relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: results_in_morphogenesis_of UBERON:0003060 ! pronephric duct created_by: bf creation_date: 2010-07-02T10:18:09Z [Term] id: GO:0040007 name: growth namespace: biological_process alt_id: GO:0048590 def: "The increase in size or mass of an entire organism, a part of an organism or a cell." [GOC:bf, GOC:ma] comment: See also the biological process term 'cell growth ; GO:0016049'. subset: gocheck_do_not_annotate subset: goslim_chembl subset: goslim_pir subset: goslim_plant synonym: "growth pattern" RELATED [] synonym: "non-developmental growth" RELATED [GOC:mah] is_a: GO:0008150 ! biological_process relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0040008 name: regulation of growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." [GOC:ems, GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0040007 ! growth relationship: regulates GO:0040007 ! growth [Term] id: GO:0040011 name: locomotion namespace: biological_process def: "Self-propelled movement of a cell or organism from one location to another." [GOC:dgh] subset: goslim_chembl subset: goslim_pir is_a: GO:0008150 ! biological_process property_value: RO:0002161 NCBITaxon:451864 [Term] id: GO:0040012 name: regulation of locomotion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." [GOC:ems] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0040011 ! locomotion relationship: regulates GO:0040011 ! locomotion [Term] id: GO:0040013 name: negative regulation of locomotion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "down regulation of locomotion" EXACT [] synonym: "down-regulation of locomotion" EXACT [] synonym: "downregulation of locomotion" EXACT [] synonym: "inhibition of locomotion" NARROW [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0040011 ! locomotion relationship: negatively_regulates GO:0040011 ! locomotion [Term] id: GO:0040014 name: regulation of multicellular organism growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035264 ! multicellular organism growth relationship: regulates GO:0035264 ! multicellular organism growth [Term] id: GO:0040015 name: negative regulation of multicellular organism growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:ems, GOC:tb] synonym: "negative regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "negative regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035264 ! multicellular organism growth relationship: negatively_regulates GO:0035264 ! multicellular organism growth [Term] id: GO:0040016 name: embryonic cleavage namespace: biological_process def: "The first few specialized divisions of an activated animal egg." [GOC:clt, ISBN:0070524300] is_a: GO:0051301 ! cell division relationship: part_of GO:0009790 ! embryo development [Term] id: GO:0040017 name: positive regulation of locomotion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." [GOC:go_curators] synonym: "activation of locomotion" NARROW [] synonym: "stimulation of locomotion" NARROW [] synonym: "up regulation of locomotion" EXACT [] synonym: "up-regulation of locomotion" EXACT [] synonym: "upregulation of locomotion" EXACT [] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0040011 ! locomotion relationship: positively_regulates GO:0040011 ! locomotion [Term] id: GO:0040018 name: positive regulation of multicellular organism growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "positive regulation of body growth" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of body size" EXACT [GOC:dph, GOC:tb] is_a: GO:0040014 ! regulation of multicellular organism growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035264 ! multicellular organism growth relationship: positively_regulates GO:0035264 ! multicellular organism growth [Term] id: GO:0040019 name: positive regulation of embryonic development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "activation of embryonic development" NARROW [] synonym: "stimulation of embryonic development" NARROW [] synonym: "up regulation of embryonic development" EXACT [] synonym: "up-regulation of embryonic development" EXACT [] synonym: "upregulation of embryonic development" EXACT [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009790 ! embryo development relationship: positively_regulates GO:0009790 ! embryo development [Term] id: GO:0040020 name: regulation of meiotic nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." [GOC:ems, GOC:ma] synonym: "regulation of meiosis" BROAD [GOC:vw] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0140013 ! meiotic nuclear division relationship: regulates GO:0140013 ! meiotic nuclear division [Term] id: GO:0040034 name: regulation of development, heterochronic namespace: biological_process def: "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." [PMID:9442909] synonym: "developmental timing" RELATED [] synonym: "heterochronic regulation of development" EXACT [] synonym: "temporal regulation of development" EXACT [] is_a: GO:0050793 ! regulation of developmental process [Term] id: GO:0042063 name: gliogenesis namespace: biological_process def: "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." [GOC:dgh, GOC:jid] synonym: "glial cell generation" EXACT systematic_synonym [] is_a: GO:0022008 ! neurogenesis intersection_of: GO:0008150 ! biological_process intersection_of: results_in_formation_of CL:0000125 ! glial cell relationship: results_in_formation_of CL:0000125 ! glial cell [Term] id: GO:0042065 name: glial cell growth namespace: biological_process def: "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of CL:0000125 ! glial cell relationship: part_of GO:0042063 ! gliogenesis relationship: results_in_growth_of CL:0000125 ! glial cell [Term] id: GO:0042069 name: regulation of catecholamine metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." [GOC:go_curators] synonym: "regulation of catecholamine metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006584 ! catecholamine metabolic process relationship: regulates GO:0006584 ! catecholamine metabolic process [Term] id: GO:0042073 name: intraciliary transport namespace: biological_process alt_id: GO:0035734 def: "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." [GOC:cilia, GOC:kmv, PMID:17981739, PMID:18180368, PMID:22869374, Reactome:R-HSA-5620924.2] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "IFT" RELATED [] synonym: "intraflagellar transport" EXACT [] synonym: "intraflagellar transport involved in cilium organization" EXACT [] synonym: "intraflagellar transport involved in microtubule-based flagellum organisation" EXACT [] xref: Wikipedia:Intraflagellar_transport is_a: GO:0010970 ! transport along microtubule is_a: GO:0031503 ! protein-containing complex localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0032991 ! protein-containing complex intersection_of: occurs_in GO:0005929 ! cilium intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: occurs_in GO:0005929 ! cilium relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0044782 ! cilium organization property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0042074 name: cell migration involved in gastrulation namespace: biological_process def: "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." [GOC:jl, http://www.cellmigration.org/, ISBN:0878932437] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0007369 ! gastrulation relationship: part_of GO:0007369 ! gastrulation [Term] id: GO:0042078 name: germ-line stem cell division namespace: biological_process alt_id: GO:0048131 def: "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." [GOC:jid, PMID:2279698] synonym: "germ-line stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000014 ! germ line stem cell relationship: has_input CL:0000014 ! germ line stem cell relationship: part_of GO:0007281 ! germ cell development [Term] id: GO:0042098 name: T cell proliferation namespace: biological_process alt_id: GO:0042111 def: "The expansion of a T cell population by cell division. Follows T cell activation." [GOC:jl] synonym: "T lymphocyte proliferation" EXACT [] synonym: "T-cell proliferation" EXACT [] synonym: "T-lymphocyte proliferation" EXACT [] is_a: GO:0042110 ! T cell activation is_a: GO:0046651 ! lymphocyte proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000084 ! T cell relationship: acts_on_population_of CL:0000084 ! T cell [Term] id: GO:0042102 name: positive regulation of T cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of T cell proliferation." [GOC:ai] synonym: "activation of T cell proliferation" NARROW [] synonym: "positive regulation of T lymphocyte proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte proliferation" EXACT [] synonym: "stimulation of T cell proliferation" NARROW [] synonym: "up regulation of T cell proliferation" EXACT [] synonym: "up-regulation of T cell proliferation" EXACT [] synonym: "upregulation of T cell proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050671 ! positive regulation of lymphocyte proliferation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042098 ! T cell proliferation relationship: positively_regulates GO:0042098 ! T cell proliferation [Term] id: GO:0042103 name: positive regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of resting T cell proliferation." [GOC:jl] synonym: "activation of T cell homeostatic proliferation" NARROW [] synonym: "positive regulation of resting T cell proliferation" EXACT [] synonym: "positive regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "positive regulation of T-cell homeostatic proliferation" EXACT [] synonym: "positive regulation of T-lymphocyte homeostatic proliferation" EXACT [] synonym: "stimulation of T cell homeostatic proliferation" NARROW [] synonym: "up regulation of T cell homeostatic proliferation" EXACT [] synonym: "up-regulation of T cell homeostatic proliferation" EXACT [] synonym: "upregulation of T cell homeostatic proliferation" EXACT [] is_a: GO:0042102 ! positive regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001777 ! T cell homeostatic proliferation relationship: positively_regulates GO:0001777 ! T cell homeostatic proliferation [Term] id: GO:0042110 name: T cell activation namespace: biological_process def: "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." [GOC:mgi_curators, ISBN:0781735149] synonym: "T lymphocyte activation" EXACT [] synonym: "T-cell activation" EXACT [] synonym: "T-lymphocyte activation" EXACT [] is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000084 ! T cell relationship: has_input CL:0000084 ! T cell [Term] id: GO:0042118 name: endothelial cell activation namespace: biological_process def: "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149, PMID:12851652, PMID:14581484] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000115 ! endothelial cell relationship: has_input CL:0000115 ! endothelial cell [Term] id: GO:0042127 name: regulation of cell population proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation." [GOC:jl] synonym: "regulation of cell proliferation" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008283 ! cell population proliferation relationship: regulates GO:0008283 ! cell population proliferation property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0042129 name: regulation of T cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell proliferation." [GOC:jl] synonym: "regulation of T lymphocyte proliferation" EXACT [] synonym: "regulation of T-cell proliferation" EXACT [] synonym: "regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042098 ! T cell proliferation relationship: regulates GO:0042098 ! T cell proliferation [Term] id: GO:0042130 name: negative regulation of T cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." [GOC:jl] synonym: "down regulation of T cell proliferation" EXACT [] synonym: "down-regulation of T cell proliferation" EXACT [] synonym: "downregulation of T cell proliferation" EXACT [] synonym: "inhibition of T cell proliferation" NARROW [] synonym: "negative regulation of T lymphocyte proliferation" EXACT [] synonym: "negative regulation of T-cell proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation is_a: GO:0050672 ! negative regulation of lymphocyte proliferation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042098 ! T cell proliferation relationship: negatively_regulates GO:0042098 ! T cell proliferation [Term] id: GO:0042133 name: neurotransmitter metabolic process namespace: biological_process def: "The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." [GOC:jl] subset: goslim_pir synonym: "neurotransmitter metabolism" EXACT [] is_a: GO:0001505 ! regulation of neurotransmitter levels is_a: GO:0044237 ! cellular metabolic process property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0042135 name: neurotransmitter catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." [GOC:jl] subset: goslim_synapse synonym: "neurotransmitter breakdown" EXACT [] synonym: "neurotransmitter catabolism" EXACT [] synonym: "neurotransmitter degradation" EXACT [] is_a: GO:0042133 ! neurotransmitter metabolic process is_a: GO:0044248 ! cellular catabolic process [Term] id: GO:0042136 name: neurotransmitter biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." [GOC:jl] subset: goslim_synapse synonym: "neurotransmitter anabolism" EXACT [] synonym: "neurotransmitter biosynthesis" EXACT [] synonym: "neurotransmitter biosynthesis and storage" BROAD [] synonym: "neurotransmitter biosynthetic process and storage" BROAD [] synonym: "neurotransmitter formation" EXACT [] synonym: "neurotransmitter synthesis" EXACT [] is_a: GO:0042133 ! neurotransmitter metabolic process is_a: GO:0044249 ! cellular biosynthetic process [Term] id: GO:0042175 name: nuclear outer membrane-endoplasmic reticulum membrane network namespace: cellular_component def: "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." [GOC:bf, GOC:jl, GOC:mah, GOC:mcc, GOC:pr, GOC:vw] synonym: "NE-ER continuum" RELATED [] synonym: "NE-ER network" RELATED [] synonym: "nuclear envelope-endoplasmic reticulum continuum" RELATED [] synonym: "nuclear envelope-endoplasmic reticulum network" RELATED [GOC:mah] synonym: "nuclear envelope-ER network" RELATED [] synonym: "nuclear membrane-endoplasmic reticulum continuum" EXACT [GOC:mah] synonym: "nuclear membrane-ER network" EXACT [GOC:mah] is_a: GO:0016020 ! membrane relationship: part_of GO:0012505 ! endomembrane system [Term] id: GO:0042176 name: regulation of protein catabolic process namespace: biological_process alt_id: GO:1903362 alt_id: GO:2000598 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators, GOC:jl] synonym: "regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein catabolic process" EXACT [] synonym: "regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "regulation of cyclin breakdown" NARROW [GOC:obol] synonym: "regulation of cyclin catabolic process" NARROW [] synonym: "regulation of cyclin catabolism" NARROW [GOC:obol] synonym: "regulation of cyclin degradation" NARROW [GOC:obol] synonym: "regulation of degradation of cyclin" NARROW [GOC:obol] synonym: "regulation of protein breakdown" EXACT [] synonym: "regulation of protein catabolism" EXACT [] synonym: "regulation of protein degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030163 ! protein catabolic process relationship: regulates GO:0030163 ! protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI created_by: kmv creation_date: 2014-08-21T15:05:45Z [Term] id: GO:0042177 name: negative regulation of protein catabolic process namespace: biological_process alt_id: GO:1903363 alt_id: GO:2000599 def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." [GO_REF:0000058, GOC:kmv, GOC:obol, GOC:TermGenie, PMID:24785082] synonym: "down regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down regulation of protein catabolic process" EXACT [] synonym: "down-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein catabolic process" EXACT [] synonym: "downregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein catabolic process" EXACT [] synonym: "inhibition of cellular protein breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein degradation" NARROW [GOC:TermGenie] synonym: "inhibition of protein catabolic process" NARROW [] synonym: "negative regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein catabolic process" EXACT [] synonym: "negative regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein breakdown" EXACT [] synonym: "negative regulation of protein catabolism" EXACT [] synonym: "negative regulation of protein degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051248 ! negative regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030163 ! protein catabolic process relationship: negatively_regulates GO:0030163 ! protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0042180 name: cellular ketone metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:jl, ISBN:0787650153] subset: goslim_pir synonym: "ketone metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process is_a: GO:0044281 ! small molecule metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:17087 ! ketone relationship: has_primary_input_or_output CHEBI:17087 ! ketone [Term] id: GO:0042181 name: ketone biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone anabolism" EXACT [] synonym: "ketone biosynthesis" EXACT [] synonym: "ketone formation" EXACT [] synonym: "ketone synthesis" EXACT [] is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0044249 ! cellular biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:17087 ! ketone relationship: has_primary_output CHEBI:17087 ! ketone [Term] id: GO:0042182 name: ketone catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." [GOC:go_curators] synonym: "ketone breakdown" EXACT [] synonym: "ketone catabolism" EXACT [] synonym: "ketone degradation" EXACT [] is_a: GO:0042180 ! cellular ketone metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:0044282 ! small molecule catabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:17087 ! ketone relationship: has_primary_input CHEBI:17087 ! ketone [Term] id: GO:0042221 name: response to chemical namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." [GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_candida subset: goslim_drosophila subset: goslim_metagenomics subset: goslim_plant subset: goslim_yeast synonym: "response to chemical stimulus" EXACT [GOC:dos] synonym: "response to chemical substance" EXACT [] is_a: GO:0050896 ! response to stimulus intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:24431 ! chemical entity relationship: has_input CHEBI:24431 ! chemical entity [Term] id: GO:0042254 name: ribosome biogenesis namespace: biological_process alt_id: GO:0007046 def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." [GOC:ma, PMID:26404467, Wikipedia:Ribosome_biogenesis] subset: goslim_candida subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: prokaryote_subset synonym: "ribosome biogenesis and assembly" EXACT [] is_a: GO:0022613 ! ribonucleoprotein complex biogenesis [Term] id: GO:0042255 name: ribosome assembly namespace: biological_process alt_id: GO:0042257 def: "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." [GOC:ma, PMID:30467428] subset: goslim_yeast synonym: "ribosomal subunit assembly" NARROW [GOC:mah, GOC:vw] is_a: GO:0140694 ! non-membrane-bounded organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005840 ! ribosome relationship: part_of GO:0042254 ! ribosome biogenesis relationship: results_in_assembly_of GO:0005840 ! ribosome [Term] id: GO:0042325 name: regulation of phosphorylation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." [GOC:jl] is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016310 ! phosphorylation relationship: regulates GO:0016310 ! phosphorylation [Term] id: GO:0042326 name: negative regulation of phosphorylation namespace: biological_process def: "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." [GOC:jl] synonym: "down regulation of phosphorylation" EXACT [] synonym: "down-regulation of phosphorylation" EXACT [] synonym: "downregulation of phosphorylation" EXACT [] synonym: "inhibition of phosphorylation" NARROW [] is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0045936 ! negative regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016310 ! phosphorylation relationship: negatively_regulates GO:0016310 ! phosphorylation [Term] id: GO:0042327 name: positive regulation of phosphorylation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." [GOC:jl] synonym: "activation of phosphorylation" NARROW [] synonym: "stimulation of phosphorylation" NARROW [] synonym: "up regulation of phosphorylation" EXACT [] synonym: "up-regulation of phosphorylation" EXACT [] synonym: "upregulation of phosphorylation" EXACT [] is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0045937 ! positive regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016310 ! phosphorylation relationship: positively_regulates GO:0016310 ! phosphorylation [Term] id: GO:0042391 name: regulation of membrane potential namespace: biological_process def: "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." [GOC:jl, GOC:mtg_cardio, GOC:tb, ISBN:0198506732] is_a: BFO:0000003 ! occurrent relationship: has_part GO:0034220 ! monoatomic ion transmembrane transport [Term] id: GO:0042401 name: biogenic amine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:jl, ISBN:0395825172] synonym: "biogenic amine anabolism" EXACT [] synonym: "biogenic amine biosynthesis" EXACT [] synonym: "biogenic amine formation" EXACT [] synonym: "biogenic amine synthesis" EXACT [] synonym: "cellular biogenic amine biosynthetic process" EXACT [] is_a: GO:0006576 ! biogenic amine metabolic process is_a: GO:0009309 ! amine biosynthetic process [Term] id: GO:0042402 name: cellular biogenic amine catabolic process namespace: biological_process def: "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." [GOC:go_curators, GOC:jl, ISBN:0198506732] synonym: "biogenic amine breakdown" EXACT [] synonym: "biogenic amine catabolism" EXACT [] synonym: "biogenic amine degradation" EXACT [] is_a: GO:0009310 ! amine catabolic process [Term] id: GO:0042415 name: norepinephrine metabolic process namespace: biological_process def: "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol metabolic process" EXACT [] synonym: "levarterenol metabolism" EXACT [] synonym: "noradrenaline metabolic process" EXACT [] synonym: "noradrenaline metabolism" EXACT [] synonym: "norepinephrine metabolism" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_input_or_output CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0042421 name: norepinephrine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol biosynthesis" EXACT [] synonym: "levarterenol biosynthetic process" EXACT [] synonym: "noradrenaline biosynthesis" EXACT [] synonym: "noradrenaline biosynthetic process" EXACT [] synonym: "norepinephrine anabolism" EXACT [] synonym: "norepinephrine biosynthesis" EXACT [] synonym: "norepinephrine formation" EXACT [] synonym: "norepinephrine synthesis" EXACT [] is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_output CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0042422 name: norepinephrine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." [GOC:jl, ISBN:0198506732] synonym: "levarterenol catabolic process" EXACT [] synonym: "levarterenol catabolism" EXACT [] synonym: "noradrenaline catabolic process" EXACT [] synonym: "noradrenaline catabolism" EXACT [] synonym: "norepinephrine breakdown" EXACT [] synonym: "norepinephrine catabolism" EXACT [] synonym: "norepinephrine degradation" EXACT [] xref: Wikipedia:Norepinephrine#Degradation is_a: GO:0042415 ! norepinephrine metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0042423 name: catecholamine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine anabolism" EXACT [] synonym: "catecholamine biosynthesis" EXACT [] synonym: "catecholamine formation" EXACT [] synonym: "catecholamine synthesis" EXACT [] xref: Wikipedia:Catecholamines is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0009713 ! catechol-containing compound biosynthetic process is_a: GO:0042401 ! biogenic amine biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33567 ! catecholamine relationship: has_primary_output CHEBI:33567 ! catecholamine [Term] id: GO:0042424 name: catecholamine catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:jl, ISBN:0198506732] synonym: "catecholamine breakdown" EXACT [] synonym: "catecholamine catabolism" EXACT [] synonym: "catecholamine degradation" EXACT [] is_a: GO:0006584 ! catecholamine metabolic process is_a: GO:0019614 ! catechol-containing compound catabolic process is_a: GO:0042402 ! cellular biogenic amine catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33567 ! catecholamine relationship: has_primary_input CHEBI:33567 ! catecholamine [Term] id: GO:0042427 name: serotonin biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin anabolism" EXACT [] synonym: "serotonin biosynthesis" EXACT [] synonym: "serotonin formation" EXACT [] synonym: "serotonin synthesis" EXACT [] xref: Wikipedia:Serotonin is_a: GO:0009058 ! biosynthetic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:350546 ! serotonin(1+) relationship: has_primary_output CHEBI:350546 ! serotonin(1+) [Term] id: GO:0042428 name: serotonin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin metabolism" EXACT [] is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0097164 ! ammonium ion metabolic process is_a: GO:1901160 ! primary amino compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:350546 ! serotonin(1+) relationship: has_primary_input_or_output CHEBI:350546 ! serotonin(1+) [Term] id: GO:0042429 name: serotonin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." [GOC:jl, ISBN:0198506732] synonym: "serotonin breakdown" EXACT [] synonym: "serotonin catabolism" EXACT [] synonym: "serotonin degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0042428 ! serotonin metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) relationship: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0042430 name: indole-containing compound metabolic process namespace: biological_process alt_id: GO:0042434 def: "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl, GOC:mah] synonym: "indole and derivative metabolic process" EXACT [] synonym: "indole and derivative metabolism" EXACT [] synonym: "indole derivative metabolic process" NARROW [] synonym: "indole derivative metabolism" NARROW [] synonym: "indole-containing compound metabolism" EXACT [] synonym: "ketole metabolic process" EXACT [] synonym: "ketole metabolism" EXACT [] is_a: GO:0006725 ! cellular aromatic compound metabolic process is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0046483 ! heterocycle metabolic process is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:24828 ! indoles relationship: has_primary_input_or_output CHEBI:24828 ! indoles [Term] id: GO:0042435 name: indole-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative biosynthesis" EXACT [] synonym: "indole derivative biosynthetic process" EXACT [] synonym: "indole-containing compound anabolism" EXACT [] synonym: "indole-containing compound biosynthesis" EXACT [] synonym: "indole-containing compound formation" EXACT [] synonym: "indole-containing compound synthesis" EXACT [] is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:24828 ! indoles relationship: has_primary_output CHEBI:24828 ! indoles [Term] id: GO:0042436 name: indole-containing compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." [GOC:jl] synonym: "indole derivative catabolic process" EXACT [] synonym: "indole derivative catabolism" EXACT [] synonym: "indole-containing compound breakdown" EXACT [] synonym: "indole-containing compound catabolism" EXACT [] synonym: "indole-containing compound degradation" EXACT [] is_a: GO:0019439 ! aromatic compound catabolic process is_a: GO:0042430 ! indole-containing compound metabolic process is_a: GO:0044270 ! cellular nitrogen compound catabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:24828 ! indoles relationship: has_primary_input CHEBI:24828 ! indoles [Term] id: GO:0042461 name: photoreceptor cell development namespace: biological_process alt_id: GO:0046531 def: "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." [GOC:go_curators] synonym: "photoreceptor morphogenesis" EXACT [] is_a: GO:0048666 ! neuron development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000210 ! photoreceptor cell relationship: part_of GO:0046530 ! photoreceptor cell differentiation relationship: results_in_development_of CL:0000210 ! photoreceptor cell [Term] id: GO:0042462 name: eye photoreceptor cell development namespace: biological_process def: "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." [GOC:jl, ISBN:0192800981] is_a: GO:0042461 ! photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000287 ! eye photoreceptor cell relationship: part_of GO:0001754 ! eye photoreceptor cell differentiation relationship: results_in_development_of CL:0000287 ! eye photoreceptor cell [Term] id: GO:0042471 name: ear morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GOC:jl, ISBN:0192801023] synonym: "hearing organ morphogenesis" EXACT [] is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001690 ! ear relationship: part_of GO:0043583 ! ear development relationship: results_in_morphogenesis_of UBERON:0001690 ! ear [Term] id: GO:0042472 name: inner ear morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively." [GOC:jl, ISBN:0192801023] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001846 ! internal ear relationship: part_of GO:0042471 ! ear morphogenesis relationship: part_of GO:0048839 ! inner ear development relationship: results_in_morphogenesis_of UBERON:0001846 ! internal ear [Term] id: GO:0042473 name: outer ear morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull." [GOC:jl, ISBN:0192801023] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001691 ! external ear relationship: part_of GO:0042471 ! ear morphogenesis relationship: results_in_morphogenesis_of UBERON:0001691 ! external ear [Term] id: GO:0042474 name: middle ear morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)." [GOC:jl, ISBN:0192801023] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001756 ! middle ear relationship: part_of GO:0042471 ! ear morphogenesis relationship: results_in_morphogenesis_of UBERON:0001756 ! middle ear [Term] id: GO:0042475 name: odontogenesis of dentin-containing tooth namespace: biological_process def: "The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel." [GOC:cjm, GOC:mah, GOC:mtg_sensu, PMID:10333884, PMID:15355794] comment: Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales. synonym: "odontogenesis of dentine-containing teeth" EXACT [] synonym: "odontogenesis of dentine-containing tooth" EXACT [GOC:mah] synonym: "odontogeny" BROAD [] synonym: "odontosis" BROAD [] synonym: "tooth development" BROAD [] is_a: GO:0042476 ! odontogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001091 ! calcareous tooth relationship: in_taxon NCBITaxon:7711 {all_only="true"} ! Chordata relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: results_in_morphogenesis_of UBERON:0001091 ! calcareous tooth [Term] id: GO:0042476 name: odontogenesis namespace: biological_process alt_id: GO:0042477 def: "The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food." [GOC:jl, GOC:mah] synonym: "odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "odontogeny" EXACT [] synonym: "odontosis" EXACT [] synonym: "tooth development" RELATED [] synonym: "tooth morphogenesis" EXACT [] xref: Wikipedia:Odontogenesis is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003913 ! tooth-like structure relationship: results_in_morphogenesis_of UBERON:0003913 ! tooth-like structure property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0042478 name: regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "regulation of eye photoreceptor development" EXACT [] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042462 ! eye photoreceptor cell development relationship: regulates GO:0042462 ! eye photoreceptor cell development [Term] id: GO:0042479 name: positive regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "activation of eye photoreceptor cell development" NARROW [] synonym: "positive regulation of eye photoreceptor development" EXACT [] synonym: "stimulation of eye photoreceptor cell development" NARROW [] synonym: "up regulation of eye photoreceptor cell development" EXACT [] synonym: "up-regulation of eye photoreceptor cell development" EXACT [] synonym: "upregulation of eye photoreceptor cell development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042462 ! eye photoreceptor cell development relationship: positively_regulates GO:0042462 ! eye photoreceptor cell development [Term] id: GO:0042480 name: negative regulation of eye photoreceptor cell development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." [GOC:jl] synonym: "down regulation of eye photoreceptor cell development" EXACT [] synonym: "down-regulation of eye photoreceptor cell development" EXACT [] synonym: "downregulation of eye photoreceptor cell development" EXACT [] synonym: "inhibition of eye photoreceptor cell development" NARROW [] synonym: "negative regulation of eye photoreceptor development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0042478 ! regulation of eye photoreceptor cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042462 ! eye photoreceptor cell development relationship: negatively_regulates GO:0042462 ! eye photoreceptor cell development [Term] id: GO:0042481 name: regulation of odontogenesis namespace: biological_process alt_id: GO:0042484 def: "Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] synonym: "regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "regulation of tooth development" EXACT [] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042476 ! odontogenesis relationship: regulates GO:0042476 ! odontogenesis [Term] id: GO:0042482 name: positive regulation of odontogenesis namespace: biological_process alt_id: GO:0042485 def: "Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] synonym: "activation of odontogenesis" NARROW [] synonym: "positive regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "positive regulation of tooth development" EXACT [] synonym: "stimulation of odontogenesis" NARROW [] synonym: "up regulation of odontogenesis" EXACT [] synonym: "up-regulation of odontogenesis" EXACT [] synonym: "upregulation of odontogenesis" EXACT [] is_a: GO:0042481 ! regulation of odontogenesis is_a: GO:0110110 ! positive regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042476 ! odontogenesis relationship: positively_regulates GO:0042476 ! odontogenesis [Term] id: GO:0042483 name: negative regulation of odontogenesis namespace: biological_process alt_id: GO:0042486 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth." [GOC:jl] synonym: "down regulation of odontogenesis" EXACT [] synonym: "down-regulation of odontogenesis" EXACT [] synonym: "downregulation of odontogenesis" EXACT [] synonym: "inhibition of odontogenesis" NARROW [] synonym: "negative regulation of odontogenesis of calcareous or chitinous tooth" NARROW [] synonym: "negative regulation of tooth development" EXACT [] is_a: GO:0042481 ! regulation of odontogenesis is_a: GO:0110111 ! negative regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042476 ! odontogenesis relationship: negatively_regulates GO:0042476 ! odontogenesis [Term] id: GO:0042487 name: regulation of odontogenesis of dentin-containing tooth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates." [GOC:jl, GOC:mtg_sensu, PMID:15355794] synonym: "regulation of odontogenesis of dentine-containing teeth" EXACT [] synonym: "regulation of odontogenesis of dentine-containing tooth" EXACT [GOC:mah] is_a: GO:0042481 ! regulation of odontogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042475 ! odontogenesis of dentin-containing tooth relationship: regulates GO:0042475 ! odontogenesis of dentin-containing tooth [Term] id: GO:0042488 name: positive regulation of odontogenesis of dentin-containing tooth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates." [GOC:jl, PMID:15355794] synonym: "activation of odontogenesis" BROAD [] synonym: "positive regulation of odontogenesis of dentine-containing teeth" EXACT [] synonym: "positive regulation of odontogenesis of dentine-containing tooth" RELATED [] synonym: "stimulation of odontogenesis" BROAD [] synonym: "up regulation of odontogenesis" BROAD [] synonym: "up-regulation of odontogenesis" BROAD [] synonym: "upregulation of odontogenesis" BROAD [] is_a: GO:0042482 ! positive regulation of odontogenesis is_a: GO:0042487 ! regulation of odontogenesis of dentin-containing tooth intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth relationship: positively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth [Term] id: GO:0042489 name: negative regulation of odontogenesis of dentin-containing tooth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx." [GOC:jl, GOC:mtg_sensu, PMID:15355794] synonym: "down regulation of odontogenesis" BROAD [] synonym: "down-regulation of odontogenesis" BROAD [] synonym: "downregulation of odontogenesis" BROAD [] synonym: "inhibition of odontogenesis" BROAD [] synonym: "negative regulation of odontogenesis" BROAD [] synonym: "negative regulation of odontogenesis of dentine-containing teeth" EXACT [] synonym: "negative regulation of odontogenesis of dentine-containing tooth" RELATED [] is_a: GO:0042483 ! negative regulation of odontogenesis is_a: GO:0042487 ! regulation of odontogenesis of dentin-containing tooth intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth relationship: negatively_regulates GO:0042475 ! odontogenesis of dentin-containing tooth [Term] id: GO:0042551 name: neuron maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." [GOC:dph, GOC:jl] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000540 ! neuron relationship: part_of GO:0048666 ! neuron development relationship: results_in_maturation_of CL:0000540 ! neuron [Term] id: GO:0042552 name: myelination namespace: biological_process def: "The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier." [GOC:dgh, GOC:mah] synonym: "myelinogenesis" RELATED [GOC:cjm, HP:0003429] xref: Wikipedia:Myelin is_a: GO:0008366 ! axon ensheathment [Term] id: GO:0042588 name: zymogen granule namespace: cellular_component def: "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." [GOC:jl, ISBN:0198506732] is_a: GO:0030141 ! secretory granule [Term] id: GO:0042589 name: zymogen granule membrane namespace: cellular_component def: "The lipid bilayer surrounding a zymogen granule." [GOC:jl] is_a: GO:0030667 ! secretory granule membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0042588 ! zymogen granule relationship: bounding_layer_of GO:0042588 ! zymogen granule relationship: part_of GO:0042588 ! zymogen granule [Term] id: GO:0042592 name: homeostatic process namespace: biological_process alt_id: GO:0032844 alt_id: GO:0032845 alt_id: GO:0032846 def: "Any biological process involved in the maintenance of an internal steady state." [GOC:jl, ISBN:0395825172] subset: goslim_agr subset: goslim_chembl subset: goslim_mouse synonym: "activation of homeostatic process" NARROW [] synonym: "homeostasis" EXACT [] synonym: "inhibition of homeostatic process" NARROW [] synonym: "negative regulation of homeostatic process" RELATED [] synonym: "positive regulation of homeostatic process" RELATED [] synonym: "regulation of homeostatic process" RELATED [] is_a: GO:0008150 ! biological_process [Term] id: GO:0042611 name: MHC protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0781735149, PMID:15928678, PMID:16153240] subset: goslim_pir is_a: GO:0098797 ! plasma membrane protein complex [Term] id: GO:0042613 name: MHC class II protein complex namespace: cellular_component def: "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." [GOC:add, GOC:jl, ISBN:0120781859, PMID:15928678] is_a: GO:0042611 ! MHC protein complex [Term] id: GO:0042641 name: actomyosin namespace: cellular_component def: "Any complex of actin, myosin, and accessory proteins." [GOC:go_curators] synonym: "actomyosin complex" EXACT [] synonym: "actomyosin structure" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of GO:0015629 ! actin cytoskeleton [Term] id: GO:0042670 name: retinal cone cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." [GOC:go_curators] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000573 ! retinal cone cell relationship: results_in_acquisition_of_features_of CL:0000573 ! retinal cone cell [Term] id: GO:0042692 name: muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." [CL:0000187, GOC:go_curators] synonym: "myogenesis" RELATED [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000187 ! muscle cell relationship: part_of GO:0061061 ! muscle structure development relationship: results_in_acquisition_of_features_of CL:0000187 ! muscle cell [Term] id: GO:0042698 name: ovulation cycle namespace: biological_process def: "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." [ISBN:0721662544] is_a: GO:0048511 ! rhythmic process is_a: GO:0048609 ! multicellular organismal reproductive process relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: GO:0042702 name: uterine wall growth namespace: biological_process def: "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels." [GOC:jl] is_a: GO:0022602 ! ovulation cycle process is_a: GO:0048589 ! developmental growth intersection_of: GO:0040007 ! growth intersection_of: results_in_growth_of UBERON:0000459 ! uterine wall relationship: part_of GO:0001553 ! luteinization relationship: results_in_growth_of UBERON:0000459 ! uterine wall [Term] id: GO:0042713 name: sperm ejaculation namespace: biological_process def: "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0007320 ! insemination [Term] id: GO:0042742 name: defense response to bacterium namespace: biological_process alt_id: GO:0009816 alt_id: GO:0042830 def: "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism." [GOC:jl] synonym: "antibacterial peptide activity" RELATED [] synonym: "defence response to bacteria" EXACT [] synonym: "defence response to bacterium" EXACT [] synonym: "defense response to bacteria" EXACT [] synonym: "defense response to bacterium, incompatible interaction" NARROW [] synonym: "resistance response to pathogenic bacteria" NARROW [] synonym: "resistance response to pathogenic bacterium" NARROW [] is_a: GO:0009617 ! response to bacterium is_a: GO:0098542 ! defense response to other organism intersection_of: GO:0006952 ! defense response intersection_of: has_input NCBITaxon:2 ! Bacteria [Term] id: GO:0042762 name: regulation of sulfur metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." [GOC:go_curators] synonym: "regulation of sulfur metabolism" EXACT [] synonym: "regulation of sulphur metabolic process" EXACT [] synonym: "regulation of sulphur metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006790 ! sulfur compound metabolic process relationship: regulates GO:0006790 ! sulfur compound metabolic process [Term] id: GO:0042886 name: amide transport namespace: biological_process def: "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl, ISBN:0198506732] subset: goslim_pir is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:32988 ! amide relationship: has_primary_input CHEBI:32988 ! amide [Term] id: GO:0042887 name: amide transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." [GOC:jl, ISBN:0198506732] synonym: "amine/amide/polyamine channel activity" NARROW [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:32988 ! amide relationship: has_primary_input CHEBI:32988 ! amide relationship: part_of GO:0042886 ! amide transport [Term] id: GO:0042981 name: regulation of apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym: "apoptosis regulator activity" RELATED [] synonym: "regulation of apoptosis" NARROW [] is_a: GO:0043067 ! regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006915 ! apoptotic process relationship: regulates GO:0006915 ! apoptotic process [Term] id: GO:0042995 name: cell projection namespace: cellular_component def: "A prolongation or process extending from a cell, e.g. a flagellum or axon." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: prokaryote_subset synonym: "cell process" BROAD [] synonym: "cellular process" BROAD [] synonym: "cellular projection" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell [Term] id: GO:0042996 name: regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] is_a: GO:0051223 ! regulation of protein transport is_a: GO:0060627 ! regulation of vesicle-mediated transport is_a: GO:1903076 ! regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043001 ! Golgi to plasma membrane protein transport relationship: regulates GO:0043001 ! Golgi to plasma membrane protein transport [Term] id: GO:0042997 name: negative regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "down regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "down-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "downregulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "inhibition of Golgi to plasma membrane protein transport" NARROW [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903077 ! negative regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport relationship: negatively_regulates GO:0043001 ! Golgi to plasma membrane protein transport [Term] id: GO:0042998 name: positive regulation of Golgi to plasma membrane protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." [GOC:jl] synonym: "activation of Golgi to plasma membrane protein transport" NARROW [] synonym: "stimulation of Golgi to plasma membrane protein transport" NARROW [] synonym: "up regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "up-regulation of Golgi to plasma membrane protein transport" EXACT [] synonym: "upregulation of Golgi to plasma membrane protein transport" EXACT [] is_a: GO:0042996 ! regulation of Golgi to plasma membrane protein transport is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903078 ! positive regulation of protein localization to plasma membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport relationship: positively_regulates GO:0043001 ! Golgi to plasma membrane protein transport [Term] id: GO:0043001 name: Golgi to plasma membrane protein transport namespace: biological_process def: "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." [ISBN:0716731363] is_a: GO:0006893 ! Golgi to plasma membrane transport is_a: GO:0015031 ! protein transport is_a: GO:0061951 ! establishment of protein localization to plasma membrane intersection_of: GO:0015031 ! protein transport intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: process_has_causal_agent GO:0031982 ! vesicle [Term] id: GO:0043005 name: neuron projection namespace: cellular_component def: "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." [GOC:jl, http://www.cogsci.princeton.edu/~wn/] subset: goslim_pir synonym: "nerve fiber" RELATED [GOC:dph] synonym: "neurite" NARROW [] synonym: "neuron process" EXACT [] synonym: "neuron protrusion" EXACT [NIF_Subcellular:sao250931889] synonym: "neuronal cell projection" EXACT [] xref: NIF_Subcellular:sao867568886 is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000540 ! neuron relationship: part_of CL:0000540 ! neuron property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0043009 name: chordate embryonic development namespace: biological_process def: "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." [GOC:mtg_sensu] is_a: GO:0009792 ! embryo development ending in birth or egg hatching relationship: in_taxon NCBITaxon:7711 {all_only="true"} ! Chordata relationship: only_in_taxon NCBITaxon:7711 ! Chordata [Term] id: GO:0043010 name: camera-type eye development namespace: biological_process alt_id: GO:0001747 alt_id: GO:0031075 def: "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:go_curators, GOC:mtg_sensu] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000019 ! camera-type eye relationship: results_in_development_of UBERON:0000019 ! camera-type eye property_value: RO:0002161 NCBITaxon:6656 [Term] id: GO:0043025 name: neuronal cell body namespace: cellular_component def: "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." [GOC:go_curators] comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. subset: goslim_pir synonym: "neuron cell body" EXACT [] synonym: "neuronal cell soma" EXACT [] xref: NIF_Subcellular:sao1044911821 xref: Wikipedia:Soma_(biology) is_a: GO:0044297 ! cell body intersection_of: GO:0044297 ! cell body intersection_of: part_of CL:0000540 ! neuron relationship: part_of GO:0036477 ! somatodendritic compartment [Term] id: GO:0043029 name: T cell homeostasis namespace: biological_process def: "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." [GOC:mgi_curators, ISBN:0781735149] comment: Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus. synonym: "T lymphocyte homeostasis" EXACT [] synonym: "T-cell homeostasis" EXACT [] synonym: "T-lymphocyte homeostasis" EXACT [] is_a: GO:0002260 ! lymphocyte homeostasis intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000084 ! T cell relationship: acts_on_population_of CL:0000084 ! T cell [Term] id: GO:0043043 name: peptide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." [GOC:dph, GOC:jl] synonym: "peptide anabolism" EXACT [] synonym: "peptide biosynthesis" EXACT [] synonym: "peptide formation" EXACT [] synonym: "peptide synthesis" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0043604 ! amide biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16670 ! peptide relationship: has_primary_output CHEBI:16670 ! peptide [Term] id: GO:0043049 name: otic placode formation namespace: biological_process def: "The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain." [GOC:go_curators, PMID:12668634] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003069 ! otic placode relationship: part_of GO:0030916 ! otic vesicle formation relationship: results_in_formation_of UBERON:0003069 ! otic placode [Term] id: GO:0043062 name: extracellular structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir subset: prokaryote_subset synonym: "extracellular structure organisation" EXACT [] synonym: "extracellular structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005576 ! extracellular region relationship: results_in_organization_of GO:0005576 ! extracellular region [Term] id: GO:0043065 name: positive regulation of apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. subset: goslim_chembl synonym: "activation of apoptosis" NARROW [] synonym: "positive regulation of apoptosis" NARROW [] synonym: "pro-apoptosis" RELATED [] synonym: "stimulation of apoptosis" NARROW [] synonym: "up regulation of apoptosis" EXACT [] synonym: "up-regulation of apoptosis" EXACT [] synonym: "upregulation of apoptosis" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043068 ! positive regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006915 ! apoptotic process relationship: positively_regulates GO:0006915 ! apoptotic process [Term] id: GO:0043066 name: negative regulation of apoptotic process namespace: biological_process alt_id: GO:0006916 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." [GOC:jl, GOC:mtg_apoptosis] comment: This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used. synonym: "anti-apoptosis" EXACT [] synonym: "apoptosis inhibitor activity" RELATED [] synonym: "down regulation of apoptosis" EXACT [] synonym: "down-regulation of apoptosis" EXACT [] synonym: "downregulation of apoptosis" EXACT [] synonym: "inhibition of apoptosis" NARROW [] synonym: "negative regulation of apoptosis" NARROW [] synonym: "pro-survival" RELATED [] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0043069 ! negative regulation of programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006915 ! apoptotic process relationship: negatively_regulates GO:0006915 ! apoptotic process [Term] id: GO:0043067 name: regulation of programmed cell death namespace: biological_process alt_id: GO:0043070 def: "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "regulation of non-apoptotic programmed cell death" NARROW [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0012501 ! programmed cell death relationship: regulates GO:0012501 ! programmed cell death [Term] id: GO:0043068 name: positive regulation of programmed cell death namespace: biological_process alt_id: GO:0043071 def: "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "activation of programmed cell death" NARROW [] synonym: "positive regulation of non-apoptotic programmed cell death" NARROW [] synonym: "stimulation of programmed cell death" NARROW [] synonym: "up regulation of programmed cell death" EXACT [] synonym: "up-regulation of programmed cell death" EXACT [] synonym: "upregulation of programmed cell death" EXACT [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0012501 ! programmed cell death relationship: positively_regulates GO:0012501 ! programmed cell death [Term] id: GO:0043069 name: negative regulation of programmed cell death namespace: biological_process alt_id: GO:0043072 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." [GOC:jl] synonym: "down regulation of programmed cell death" EXACT [] synonym: "down-regulation of programmed cell death" EXACT [] synonym: "downregulation of programmed cell death" EXACT [] synonym: "inhibition of programmed cell death" NARROW [] synonym: "negative regulation of non-apoptotic programmed cell death" NARROW [] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0012501 ! programmed cell death relationship: negatively_regulates GO:0012501 ! programmed cell death [Term] id: GO:0043073 name: germ cell nucleus namespace: cellular_component def: "The nucleus of a germ cell, a reproductive cell in multicellular organisms." [CL:0000586, GOC:go_curators] synonym: "germ-cell nucleus" EXACT [] is_a: GO:0005634 ! nucleus intersection_of: GO:0005634 ! nucleus intersection_of: part_of CL:0000586 ! germ cell relationship: part_of CL:0000586 ! germ cell [Term] id: GO:0043085 name: positive regulation of catalytic activity namespace: biological_process alt_id: GO:0048554 def: "Any process that activates or increases the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: goslim_chembl subset: term_scheduled_for_obsoletion synonym: "activation of enzyme activity" NARROW [] synonym: "activation of metalloenzyme activity" NARROW [] synonym: "positive regulation of enzyme activity" EXACT [GOC:tb] synonym: "positive regulation of metalloenzyme activity" NARROW [] synonym: "stimulation of enzyme activity" NARROW [] synonym: "stimulation of metalloenzyme activity" NARROW [] synonym: "up regulation of enzyme activity" EXACT [] synonym: "up regulation of metalloenzyme activity" NARROW [] synonym: "up-regulation of enzyme activity" EXACT [] synonym: "up-regulation of metalloenzyme activity" NARROW [] synonym: "upregulation of enzyme activity" EXACT [] synonym: "upregulation of metalloenzyme activity" NARROW [] is_a: GO:0044093 ! positive regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003824 ! catalytic activity relationship: positively_regulates GO:0003824 ! catalytic activity [Term] id: GO:0043086 name: negative regulation of catalytic activity namespace: biological_process alt_id: GO:0048553 def: "Any process that stops or reduces the activity of an enzyme." [GOC:ebc, GOC:jl, GOC:tb, GOC:vw] subset: term_scheduled_for_obsoletion synonym: "down regulation of enzyme activity" EXACT [] synonym: "down regulation of metalloenzyme activity" NARROW [] synonym: "down-regulation of enzyme activity" EXACT [] synonym: "down-regulation of metalloenzyme activity" EXACT [] synonym: "downregulation of enzyme activity" EXACT [] synonym: "downregulation of metalloenzyme activity" NARROW [] synonym: "inhibition of enzyme activity" NARROW [] synonym: "inhibition of metalloenzyme activity" NARROW [] synonym: "negative regulation of enzyme activity" EXACT [GOC:tb] synonym: "negative regulation of metalloenzyme activity" NARROW [] is_a: GO:0044092 ! negative regulation of molecular function is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003824 ! catalytic activity relationship: negatively_regulates GO:0003824 ! catalytic activity [Term] id: GO:0043129 name: surfactant homeostasis namespace: biological_process alt_id: GO:0050828 def: "Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid." [PMID:23708874, PMID:9751757] synonym: "regulation of liquid surface tension" RELATED [] synonym: "regulation of surface tension of a liquid" RELATED [] synonym: "surfactant activity" RELATED [] is_a: GO:0048871 ! multicellular organismal-level homeostasis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24222" xsd:anyURI [Term] id: GO:0043133 name: hindgut contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, GOC:mtg_muscle, UBERON:0001046] is_a: GO:0006939 ! smooth muscle contraction is_a: GO:0022600 ! digestive system process intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: occurs_in UBERON:0001046 ! hindgut relationship: occurs_in UBERON:0001046 ! hindgut [Term] id: GO:0043134 name: regulation of hindgut contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:jl, UBERON:0001046] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044058 ! regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043133 ! hindgut contraction relationship: regulates GO:0043133 ! hindgut contraction [Term] id: GO:0043143 name: regulation of translation by machinery localization namespace: biological_process def: "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." [GOC:jl] synonym: "establishment and maintenance of translational machinery localization" EXACT [] synonym: "establishment and maintenance of translational protein localization" EXACT [] synonym: "regulation of translation by machinery localisation" EXACT [GOC:mah] synonym: "translational machinery localization" EXACT [GOC:dph, GOC:tb] synonym: "translational protein localization" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: part_of GO:0006412 ! translation relationship: part_of GO:0006412 ! translation [Term] id: GO:0043170 name: macromolecule metabolic process namespace: biological_process alt_id: GO:0034960 alt_id: GO:0043283 alt_id: GO:0044259 def: "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:mah] subset: goslim_pir synonym: "biopolymer metabolic process" EXACT [GOC:mtg_chebi_dec09] synonym: "macromolecule metabolism" EXACT [] synonym: "multicellular organismal macromolecule metabolic process" NARROW [] synonym: "organismal macromolecule metabolism" EXACT [] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33694 ! biomacromolecule relationship: has_primary_input_or_output CHEBI:33694 ! biomacromolecule [Term] id: GO:0043171 name: peptide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." [GOC:jl] synonym: "peptide breakdown" EXACT [] synonym: "peptide catabolism" EXACT [] synonym: "peptide degradation" EXACT [] is_a: GO:0006518 ! peptide metabolic process is_a: GO:0044248 ! cellular catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:16670 ! peptide relationship: has_primary_input CHEBI:16670 ! peptide [Term] id: GO:0043200 name: response to amino acid namespace: biological_process alt_id: GO:0010237 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." [GOC:ef, GOC:mlg] synonym: "response to amino acid stimulus" EXACT [GOC:dos] is_a: GO:0001101 ! response to acid chemical is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:33709 ! amino acid relationship: has_input CHEBI:33709 ! amino acid [Term] id: GO:0043207 name: response to external biotic stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." [GOC:go_curators] is_a: GO:0009605 ! response to external stimulus is_a: GO:0009607 ! response to biotic stimulus [Term] id: GO:0043209 name: myelin sheath namespace: cellular_component def: "An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system." [GOC:cjm, GOC:jl, NIF_Subcellular:sao593830697, Wikipedia:Myelin] synonym: "astrocyte sheath" NARROW [NIF_Subcellular:nlx_subcell_20090204] synonym: "oligodendrocyte myelin sheath" NARROW [NIF_Subcellular:sao1279474730] synonym: "Schwann cell myelin sheath" NARROW [] xref: FMA:62983 xref: NIF_Subcellular:sao593830697 xref: Wikipedia:Myelin is_a: GO:0110165 ! cellular anatomical entity relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of CL:0000125 ! glial cell [Term] id: GO:0043226 name: organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_chembl subset: goslim_generic subset: goslim_pir subset: prokaryote_subset xref: NIF_Subcellular:sao1539965131 xref: Wikipedia:Organelle is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0043227 name: membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] synonym: "membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao414196390 is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: has_part GO:0016020 ! membrane disjoint_from: GO:0043228 ! non-membrane-bounded organelle relationship: has_part GO:0016020 ! membrane [Term] id: GO:0043228 name: non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: goslim_mouse synonym: "biological condensate" NARROW [] synonym: "non-membrane-enclosed organelle" EXACT [] xref: NIF_Subcellular:sao1456184038 is_a: GO:0043226 ! organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21881" xsd:anyURI [Term] id: GO:0043229 name: intracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure disjoint_from: GO:0043230 ! extracellular organelle relationship: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043230 name: extracellular organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." [GOC:jl, PMID:9914479] subset: goslim_pir is_a: GO:0043226 ! organelle intersection_of: GO:0043226 ! organelle intersection_of: part_of GO:0005576 ! extracellular region relationship: part_of GO:0005576 ! extracellular region [Term] id: GO:0043231 name: intracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." [GOC:go_curators] subset: goslim_pir synonym: "intracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043232 name: intracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." [GOC:go_curators] subset: goslim_pir synonym: "intracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! non-membrane-bounded organelle is_a: GO:0043229 ! intracellular organelle intersection_of: GO:0043228 ! non-membrane-bounded organelle intersection_of: part_of GO:0005622 ! intracellular anatomical structure [Term] id: GO:0043233 name: organelle lumen namespace: cellular_component def: "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." [GOC:jl, GOC:mah] subset: goslim_mouse is_a: GO:0031974 ! membrane-enclosed lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0043226 ! organelle relationship: part_of GO:0043226 ! organelle [Term] id: GO:0043242 name: negative regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "down regulation of protein complex disassembly" EXACT [] synonym: "down-regulation of protein complex disassembly" EXACT [] synonym: "downregulation of protein complex disassembly" EXACT [] synonym: "inhibition of protein complex disassembly" NARROW [] synonym: "negative regulation of protein complex disassembly" RELATED [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032984 ! protein-containing complex disassembly relationship: negatively_regulates GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0043243 name: positive regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "activation of protein complex disassembly" NARROW [] synonym: "positive regulation of protein complex disassembly" RELATED [] synonym: "stimulation of protein complex disassembly" NARROW [] synonym: "up regulation of protein complex disassembly" EXACT [] synonym: "up-regulation of protein complex disassembly" EXACT [] synonym: "upregulation of protein complex disassembly" EXACT [] is_a: GO:0043244 ! regulation of protein-containing complex disassembly is_a: GO:0051130 ! positive regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032984 ! protein-containing complex disassembly relationship: positively_regulates GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0043244 name: regulation of protein-containing complex disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." [GOC:jl] synonym: "regulation of protein complex disassembly" RELATED [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032984 ! protein-containing complex disassembly relationship: regulates GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0043249 name: erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." [GOC:devbiol, GOC:jl] synonym: "RBC maturation" EXACT [CL:0000232] synonym: "red blood cell maturation" EXACT [CL:0000232] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000232 ! erythrocyte relationship: part_of GO:0048821 ! erythrocyte development relationship: results_in_maturation_of CL:0000232 ! erythrocyte [Term] id: GO:0043254 name: regulation of protein-containing complex assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein complex assembly." [GOC:jl] synonym: "regulation of protein complex assembly" RELATED [] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0065003 ! protein-containing complex assembly relationship: regulates GO:0065003 ! protein-containing complex assembly [Term] id: GO:0043255 name: regulation of carbohydrate biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." [GOC:jl] synonym: "regulation of carbohydrate anabolism" EXACT [] synonym: "regulation of carbohydrate biosynthesis" EXACT [] synonym: "regulation of carbohydrate formation" EXACT [] synonym: "regulation of carbohydrate synthesis" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009889 ! regulation of biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016051 ! carbohydrate biosynthetic process relationship: regulates GO:0016051 ! carbohydrate biosynthetic process [Term] id: GO:0043264 name: extracellular non-membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:jl] synonym: "extracellular non-membrane-enclosed organelle" EXACT [] is_a: GO:0043228 ! non-membrane-bounded organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043228 ! non-membrane-bounded organelle intersection_of: part_of GO:0005576 ! extracellular region [Term] id: GO:0043269 name: regulation of monoatomic ion transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "regulation of ion transport" BROAD [] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006811 ! monoatomic ion transport relationship: regulates GO:0006811 ! monoatomic ion transport [Term] id: GO:0043270 name: positive regulation of monoatomic ion transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "activation of ion transport" NARROW [] synonym: "stimulation of ion transport" NARROW [] synonym: "up regulation of ion transport" EXACT [] synonym: "up-regulation of ion transport" EXACT [] synonym: "upregulation of ion transport" EXACT [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006811 ! monoatomic ion transport relationship: positively_regulates GO:0006811 ! monoatomic ion transport [Term] id: GO:0043271 name: negative regulation of monoatomic ion transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:jl] synonym: "down regulation of ion transport" EXACT [] synonym: "down-regulation of ion transport" EXACT [] synonym: "downregulation of ion transport" EXACT [] synonym: "inhibition of ion transport" NARROW [] synonym: "negative regulation of ion transport" BROAD [] is_a: GO:0043269 ! regulation of monoatomic ion transport is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006811 ! monoatomic ion transport relationship: negatively_regulates GO:0006811 ! monoatomic ion transport [Term] id: GO:0043279 name: response to alkaloid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." [GOC:jl] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:22315 ! alkaloid relationship: has_input CHEBI:22315 ! alkaloid [Term] id: GO:0043282 name: pharyngeal muscle development namespace: biological_process def: "The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx." [GOC:go_curators] is_a: GO:0007517 ! muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000933 ! chordate pharyngeal muscle relationship: part_of GO:0060465 ! pharynx development relationship: results_in_development_of UBERON:0000933 ! chordate pharyngeal muscle [Term] id: GO:0043292 name: contractile fiber namespace: cellular_component def: "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." [GOC:go_curators, ISBN:0815316194] synonym: "contractile fibre" EXACT [] is_a: GO:0043232 ! intracellular non-membrane-bounded organelle is_a: GO:0099512 ! supramolecular fiber relationship: part_of CL:0000187 ! muscle cell relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0043353 name: enucleate erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus." [GOC:go_curators] synonym: "enucleate RBC differentiation" EXACT [CL:0000232] synonym: "enucleate red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0030218 ! erythrocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000595 ! enucleate erythrocyte relationship: results_in_acquisition_of_features_of CL:0000595 ! enucleate erythrocyte [Term] id: GO:0043354 name: enucleate erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus." [GOC:go_curators] synonym: "enucleate RBC maturation" EXACT [CL:0000232] synonym: "enucleate red blood cell maturation" EXACT [CL:0000232] is_a: GO:0043249 ! erythrocyte maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000595 ! enucleate erythrocyte relationship: part_of GO:0048822 ! enucleate erythrocyte development relationship: results_in_maturation_of CL:0000595 ! enucleate erythrocyte [Term] id: GO:0043362 name: nucleate erythrocyte maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." [GOC:devbiol, GOC:jl] synonym: "nucleate RBC maturation" EXACT [CL:0000232] synonym: "nucleate red blood cell maturation" EXACT [CL:0000232] is_a: GO:0043249 ! erythrocyte maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000562 ! nucleate erythrocyte relationship: part_of GO:0048823 ! nucleate erythrocyte development relationship: results_in_maturation_of CL:0000562 ! nucleate erythrocyte [Term] id: GO:0043363 name: nucleate erythrocyte differentiation namespace: biological_process def: "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." [GOC:jl] synonym: "nucleate RBC differentiation" EXACT [CL:0000232] synonym: "nucleate red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0030218 ! erythrocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000562 ! nucleate erythrocyte relationship: results_in_acquisition_of_features_of CL:0000562 ! nucleate erythrocyte [Term] id: GO:0043434 name: response to peptide hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." [PMID:11027914, PMID:15134857, Wikipedia:Peptide_hormone] synonym: "response to peptide hormone stimulus" EXACT [GOC:dos] synonym: "response to polypeptide hormone stimulus" EXACT [] is_a: GO:0009725 ! response to hormone is_a: GO:1901652 ! response to peptide intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:25905 ! peptide hormone relationship: has_input CHEBI:25905 ! peptide hormone [Term] id: GO:0043436 name: oxoacid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." [Wikipedia:Oxyacid] synonym: "keto acid metabolic process" EXACT [] synonym: "keto acid metabolism" EXACT [] synonym: "ketoacid metabolic process" EXACT [] synonym: "ketoacid metabolism" EXACT [] synonym: "oxo acid metabolic process" EXACT [] synonym: "oxo acid metabolism" EXACT [] synonym: "oxoacid metabolism" EXACT [] is_a: GO:0006082 ! organic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35406 ! oxoanion relationship: has_primary_input_or_output CHEBI:35406 ! oxoanion [Term] id: GO:0043455 name: regulation of secondary metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] synonym: "regulation of secondary metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019748 ! secondary metabolic process relationship: regulates GO:0019748 ! secondary metabolic process [Term] id: GO:0043467 name: regulation of generation of precursor metabolites and energy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." [GOC:jl] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006091 ! generation of precursor metabolites and energy relationship: regulates GO:0006091 ! generation of precursor metabolites and energy [Term] id: GO:0043470 name: regulation of carbohydrate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." [GOC:mlg] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016052 ! carbohydrate catabolic process relationship: regulates GO:0016052 ! carbohydrate catabolic process [Term] id: GO:0043473 name: pigmentation namespace: biological_process def: "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." [GOC:jl] subset: goslim_chembl subset: goslim_pir is_a: GO:0008150 ! biological_process relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0043500 name: muscle adaptation namespace: biological_process def: "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] subset: goslim_pir synonym: "muscle plasticity" RELATED [] is_a: GO:0003012 ! muscle system process is_a: GO:0050896 ! response to stimulus relationship: occurs_in UBERON:0002385 ! muscle tissue [Term] id: GO:0043501 name: skeletal muscle adaptation namespace: biological_process def: "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." [GOC:mtg_muscle, PMID:11181628, PMID:11449884, PMID:12605307] synonym: "skeletal muscle plasticity" RELATED [] is_a: GO:0014888 ! striated muscle adaptation intersection_of: GO:0043500 ! muscle adaptation intersection_of: occurs_in UBERON:0001134 ! skeletal muscle tissue relationship: occurs_in UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0043502 name: regulation of muscle adaptation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle adaptation." [GOC:go_curators, GOC:mtg_muscle] synonym: "regulation of muscle plasticity" RELATED [] is_a: GO:0048583 ! regulation of response to stimulus is_a: GO:0090257 ! regulation of muscle system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043500 ! muscle adaptation relationship: regulates GO:0043500 ! muscle adaptation [Term] id: GO:0043523 name: regulation of neuron apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of neuronal cells" EXACT [] synonym: "regulation of apoptosis of neurons" EXACT [] synonym: "regulation of neuron apoptosis" NARROW [] synonym: "regulation of neuron programmed cell death" EXACT [] synonym: "regulation of neuronal cell programmed cell death" EXACT [] synonym: "regulation of programmed cell death of neuronal cells" EXACT [] synonym: "regulation of programmed cell death, neurons" EXACT [] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:1901214 ! regulation of neuron death intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051402 ! neuron apoptotic process relationship: regulates GO:0051402 ! neuron apoptotic process [Term] id: GO:0043524 name: negative regulation of neuron apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "down regulation of neuron apoptosis" EXACT [] synonym: "down-regulation of neuron apoptosis" EXACT [] synonym: "downregulation of neuron apoptosis" EXACT [] synonym: "inhibition of neuron apoptosis" NARROW [] synonym: "negative regulation of neuron apoptosis" NARROW [] synonym: "negative regulation of programmed cell death, neurons" EXACT [] synonym: "neuron survival" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process is_a: GO:1901215 ! negative regulation of neuron death intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051402 ! neuron apoptotic process relationship: negatively_regulates GO:0051402 ! neuron apoptotic process [Term] id: GO:0043525 name: positive regulation of neuron apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." [GOC:go_curators, GOC:mtg_apoptosis] synonym: "activation of neuron apoptosis" NARROW [] synonym: "positive regulation of neuron apoptosis" NARROW [] synonym: "positive regulation of programmed cell death, neurons" EXACT [] synonym: "stimulation of neuron apoptosis" NARROW [] synonym: "up regulation of neuron apoptosis" EXACT [] synonym: "up-regulation of neuron apoptosis" EXACT [] synonym: "upregulation of neuron apoptosis" EXACT [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0043523 ! regulation of neuron apoptotic process is_a: GO:1901216 ! positive regulation of neuron death intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051402 ! neuron apoptotic process relationship: positively_regulates GO:0051402 ! neuron apoptotic process [Term] id: GO:0043534 name: blood vessel endothelial cell migration namespace: biological_process def: "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." [PMID:11166264] is_a: GO:0043542 ! endothelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000071 ! blood vessel endothelial cell relationship: results_in_movement_of CL:0000071 ! blood vessel endothelial cell [Term] id: GO:0043535 name: regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] is_a: GO:0010594 ! regulation of endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043534 ! blood vessel endothelial cell migration relationship: regulates GO:0043534 ! blood vessel endothelial cell migration [Term] id: GO:0043536 name: positive regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "activation of blood vessel endothelial cell migration" NARROW [] synonym: "stimulation of blood vessel endothelial cell migration" NARROW [] synonym: "up regulation of blood vessel endothelial cell migration" EXACT [] synonym: "up-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "upregulation of blood vessel endothelial cell migration" EXACT [] is_a: GO:0010595 ! positive regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043534 ! blood vessel endothelial cell migration relationship: positively_regulates GO:0043534 ! blood vessel endothelial cell migration [Term] id: GO:0043537 name: negative regulation of blood vessel endothelial cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." [GOC:go_curators] synonym: "down regulation of blood vessel endothelial cell migration" EXACT [] synonym: "down-regulation of blood vessel endothelial cell migration" EXACT [] synonym: "downregulation of blood vessel endothelial cell migration" EXACT [] synonym: "inhibition of blood vessel endothelial cell migration" NARROW [] is_a: GO:0010596 ! negative regulation of endothelial cell migration is_a: GO:0043535 ! regulation of blood vessel endothelial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration relationship: negatively_regulates GO:0043534 ! blood vessel endothelial cell migration [Term] id: GO:0043542 name: endothelial cell migration namespace: biological_process def: "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." [GOC:go_curators] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000115 ! endothelial cell relationship: results_in_movement_of CL:0000115 ! endothelial cell [Term] id: GO:0043549 name: regulation of kinase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." [GOC:bf] subset: term_scheduled_for_obsoletion is_a: GO:0042325 ! regulation of phosphorylation is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016301 ! kinase activity relationship: regulates GO:0016301 ! kinase activity [Term] id: GO:0043576 name: regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: regulates GO:0007585 ! respiratory gaseous exchange by respiratory system [Term] id: GO:0043583 name: ear development namespace: biological_process def: "The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GOC:jl, ISBN:0192801023] synonym: "hearing organ development" EXACT [] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001690 ! ear relationship: results_in_development_of UBERON:0001690 ! ear [Term] id: GO:0043584 name: nose development namespace: biological_process def: "The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [GOC:jl] synonym: "nasus development" EXACT [] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000004 ! nose relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0000004 ! nose [Term] id: GO:0043585 name: nose morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)." [GOC:jl] synonym: "nasus morphogenesis" EXACT [] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000004 ! nose relationship: part_of GO:0043584 ! nose development relationship: results_in_morphogenesis_of UBERON:0000004 ! nose [Term] id: GO:0043586 name: tongue development namespace: biological_process def: "The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." [GOC:jl, UBERON:0001723] synonym: "glossa development" NARROW [] synonym: "lingua development" NARROW [] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001723 ! tongue relationship: results_in_development_of UBERON:0001723 ! tongue [Term] id: GO:0043587 name: tongue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech." [GOC:jl, UBERON:0001723] synonym: "glossa morphogenesis" NARROW [] synonym: "lingua morphogenesis" EXACT [] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001723 ! tongue relationship: part_of GO:0043586 ! tongue development relationship: results_in_morphogenesis_of UBERON:0001723 ! tongue [Term] id: GO:0043588 name: skin development namespace: biological_process def: "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] synonym: "animal skin development" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002097 ! skin of body relationship: results_in_development_of UBERON:0002097 ! skin of body property_value: RO:0002161 NCBITaxon:50557 property_value: RO:0002161 NCBITaxon:6656 [Term] id: GO:0043589 name: skin morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." [GOC:jl, UBERON:0002097] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002097 ! skin of body relationship: part_of GO:0043588 ! skin development relationship: results_in_morphogenesis_of UBERON:0002097 ! skin of body [Term] id: GO:0043603 name: amide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." [GOC:curators] subset: goslim_pir synonym: "amide metabolism" EXACT [] synonym: "cellular amide metabolic process" EXACT [] is_a: GO:0006807 ! nitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:32988 ! amide relationship: has_primary_input_or_output CHEBI:32988 ! amide [Term] id: GO:0043604 name: amide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] is_a: GO:0043603 ! amide metabolic process is_a: GO:0044271 ! cellular nitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:32988 ! amide relationship: has_primary_output CHEBI:32988 ! amide [Term] id: GO:0043605 name: amide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." [GOC:curators] synonym: "cellular amide catabolic process" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0043603 ! amide metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_output CHEBI:32988 ! amide relationship: has_primary_output CHEBI:32988 ! amide [Term] id: GO:0043648 name: dicarboxylic acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." [ISBN:0198506732] synonym: "dicarboxylate metabolic process" EXACT [] synonym: "dicarboxylate metabolism" EXACT [] synonym: "dicarboxylic acid metabolism" EXACT [] is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_input_or_output CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0043649 name: dicarboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate catabolic process" EXACT [] synonym: "dicarboxylate catabolism" EXACT [] synonym: "dicarboxylic acid breakdown" EXACT [] synonym: "dicarboxylic acid catabolism" EXACT [] synonym: "dicarboxylic acid degradation" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_input CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0043650 name: dicarboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "dicarboxylate biosynthesis" EXACT [] synonym: "dicarboxylate biosynthetic process" EXACT [] synonym: "dicarboxylic acid anabolism" EXACT [] synonym: "dicarboxylic acid biosynthesis" EXACT [] synonym: "dicarboxylic acid formation" EXACT [] synonym: "dicarboxylic acid synthesis" EXACT [] is_a: GO:0043648 ! dicarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35693 ! dicarboxylic acid anion relationship: has_primary_output CHEBI:35693 ! dicarboxylic acid anion [Term] id: GO:0043931 name: ossification involved in bone maturation namespace: biological_process def: "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." [GOC:dph, GOC:mah, GOC:mtg_mpo] synonym: "ossification involved in bone modeling" NARROW [GO_REF:0000034] synonym: "ossification involved in skeletal development" EXACT [GOC:dph] is_a: GO:0001503 ! ossification intersection_of: GO:0001503 ! ossification intersection_of: part_of GO:0070977 ! bone maturation relationship: part_of GO:0070977 ! bone maturation [Term] id: GO:0043933 name: protein-containing complex organization namespace: biological_process alt_id: GO:0034600 alt_id: GO:0034621 alt_id: GO:0071822 def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." [GOC:mah] synonym: "cellular macromolecular complex organization" RELATED [] synonym: "cellular macromolecular complex subunit organisation" RELATED [] synonym: "cellular macromolecular complex subunit organization" RELATED [] synonym: "macromolecular complex organization" RELATED [] synonym: "macromolecular complex subunit organisation" RELATED [] synonym: "macromolecular complex subunit organization" RELATED [] synonym: "protein complex subunit organisation" EXACT [GOC:mah] synonym: "protein complex subunit organization" EXACT [] synonym: "protein-containing complex subunit organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0032991 ! protein-containing complex relationship: results_in_organization_of GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI created_by: mah creation_date: 2010-09-08T10:01:42Z [Term] id: GO:0044042 name: glucan metabolic process namespace: biological_process def: "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." [GOC:jl] synonym: "glucan metabolism" EXACT [] is_a: GO:0005976 ! polysaccharide metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:37163 ! glucan relationship: has_primary_input_or_output CHEBI:37163 ! glucan [Term] id: GO:0044057 name: regulation of system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." [GOC:jl] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003008 ! system process relationship: regulates GO:0003008 ! system process [Term] id: GO:0044058 name: regulation of digestive system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jl] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022600 ! digestive system process relationship: regulates GO:0022600 ! digestive system process [Term] id: GO:0044060 name: regulation of endocrine process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [GOC:jl] synonym: "regulation of endocrine system process" EXACT [] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050886 ! endocrine process relationship: regulates GO:0050886 ! endocrine process [Term] id: GO:0044062 name: regulation of excretion namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." [GOC:jl] is_a: GO:0044057 ! regulation of system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007588 ! excretion relationship: regulates GO:0007588 ! excretion [Term] id: GO:0044065 name: regulation of respiratory system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." [GOC:jl] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003016 ! respiratory system process relationship: regulates GO:0003016 ! respiratory system process [Term] id: GO:0044085 name: cellular component biogenesis namespace: biological_process alt_id: GO:0071843 def: "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." [GOC:jl, GOC:mah] subset: goslim_pir synonym: "cellular component biogenesis at cellular level" EXACT [] is_a: GO:0071840 ! cellular component organization or biogenesis [Term] id: GO:0044087 name: regulation of cellular component biogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044085 ! cellular component biogenesis relationship: regulates GO:0044085 ! cellular component biogenesis [Term] id: GO:0044088 name: regulation of vacuole organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "regulation of vacuole biogenesis" RELATED [GOC:mah] synonym: "regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007033 ! vacuole organization relationship: regulates GO:0007033 ! vacuole organization [Term] id: GO:0044089 name: positive regulation of cellular component biogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." [GOC:jl] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044085 ! cellular component biogenesis relationship: positively_regulates GO:0044085 ! cellular component biogenesis [Term] id: GO:0044090 name: positive regulation of vacuole organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." [GOC:jl, GOC:mah] synonym: "positive regulation of vacuole biogenesis" RELATED [GOC:mah] synonym: "positive regulation of vacuole organisation" EXACT [GOC:mah] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044088 ! regulation of vacuole organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007033 ! vacuole organization relationship: positively_regulates GO:0007033 ! vacuole organization [Term] id: GO:0044091 name: membrane biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." [GOC:jl] is_a: GO:0044085 ! cellular component biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: has_output GO:0016020 ! membrane relationship: has_output GO:0016020 ! membrane [Term] id: GO:0044092 name: negative regulation of molecular function namespace: biological_process def: "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] subset: term_scheduled_for_obsoletion is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003674 ! molecular_function relationship: negatively_regulates GO:0003674 ! molecular_function created_by: jl creation_date: 2009-04-21T04:07:27Z [Term] id: GO:0044093 name: positive regulation of molecular function namespace: biological_process def: "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GO:jl] subset: term_scheduled_for_obsoletion is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003674 ! molecular_function relationship: positively_regulates GO:0003674 ! molecular_function created_by: jl creation_date: 2009-04-21T04:11:06Z [Term] id: GO:0044207 name: translation initiation ternary complex namespace: cellular_component def: "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." [GOC:jl] synonym: "Met-tRNA/eIF2.GTP ternary complex" NARROW [] synonym: "translation initiation (ternary) complex" EXACT [] is_a: GO:1990904 ! ribonucleoprotein complex relationship: part_of GO:0005737 ! cytoplasm created_by: jl creation_date: 2009-10-22T02:38:55Z [Term] id: GO:0044237 name: cellular metabolic process namespace: biological_process def: "The chemical reactions and pathways by which individual cells transform chemical substances." [GOC:go_curators] comment: This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term. subset: gocheck_do_not_annotate synonym: "cellular metabolism" EXACT [] synonym: "intermediary metabolism" RELATED [GOC:mah] is_a: GO:0008152 ! metabolic process is_a: GO:0009987 ! cellular process [Term] id: GO:0044238 name: primary metabolic process namespace: biological_process def: "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [GOC:go_curators, http://www.metacyc.org] subset: goslim_pir synonym: "primary metabolism" EXACT [] is_a: GO:0008152 ! metabolic process [Term] id: GO:0044248 name: cellular catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." [GOC:jl] synonym: "cellular breakdown" EXACT [] synonym: "cellular catabolism" EXACT [] synonym: "cellular degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0044249 name: cellular biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." [GOC:jl] synonym: "cellular anabolism" EXACT [] synonym: "cellular biosynthesis" EXACT [] synonym: "cellular formation" EXACT [] synonym: "cellular synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044237 ! cellular metabolic process [Term] id: GO:0044258 name: intestinal lipid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas." [GOC:jl, http://www.emc.maricopa.edu/] synonym: "intestinal lipid breakdown" EXACT [] synonym: "intestinal lipid catabolism" EXACT [] synonym: "intestinal lipid degradation" EXACT [] is_a: GO:0016042 ! lipid catabolic process intersection_of: GO:0016042 ! lipid catabolic process intersection_of: occurs_in UBERON:0000160 ! intestine relationship: occurs_in UBERON:0000160 ! intestine [Term] id: GO:0044270 name: cellular nitrogen compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] synonym: "nitrogen compound breakdown" BROAD [] synonym: "nitrogen compound catabolism" BROAD [] synonym: "nitrogen compound degradation" BROAD [] is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044248 ! cellular catabolic process [Term] id: GO:0044271 name: cellular nitrogen compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." [GOC:jl, ISBN:0198506732] synonym: "nitrogen compound anabolism" BROAD [] synonym: "nitrogen compound biosynthesis" BROAD [] synonym: "nitrogen compound formation" BROAD [] synonym: "nitrogen compound synthesis" BROAD [] is_a: GO:0034641 ! cellular nitrogen compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process [Term] id: GO:0044272 name: sulfur compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur biosynthesis" NARROW [] synonym: "sulfur biosynthetic process" NARROW [] synonym: "sulfur compound anabolism" EXACT [] synonym: "sulfur compound biosynthesis" EXACT [] synonym: "sulfur compound formation" EXACT [] synonym: "sulfur compound synthesis" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0044249 ! cellular biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:26835 ! sulfur molecular entity relationship: has_primary_output CHEBI:26835 ! sulfur molecular entity [Term] id: GO:0044273 name: sulfur compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." [GOC:jl] synonym: "sulfur catabolic process" NARROW [] synonym: "sulfur catabolism" NARROW [] synonym: "sulfur compound breakdown" EXACT [] synonym: "sulfur compound catabolism" EXACT [] synonym: "sulfur compound degradation" EXACT [] is_a: GO:0006790 ! sulfur compound metabolic process is_a: GO:0044248 ! cellular catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity [Term] id: GO:0044281 name: small molecule metabolic process namespace: biological_process def: "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_metagenomics synonym: "small molecule metabolism" EXACT [] is_a: GO:0008152 ! metabolic process created_by: jl creation_date: 2010-01-26T12:05:20Z [Term] id: GO:0044282 name: small molecule catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. synonym: "small molecule catabolism" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0044281 ! small molecule metabolic process created_by: jl creation_date: 2010-01-26T12:06:10Z [Term] id: GO:0044283 name: small molecule biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." [GOC:curators, GOC:pde, GOC:vw] comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. subset: prokaryote_subset synonym: "small molecule biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0044281 ! small molecule metabolic process created_by: jl creation_date: 2010-01-26T12:06:49Z [Term] id: GO:0044297 name: cell body namespace: cellular_component def: "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." [GOC:go_curators] comment: Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. synonym: "cell soma" EXACT [] xref: FBbt:00005107 xref: FMA:67301 xref: Wikipedia:Cell_body is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell property_value: RO:0002161 NCBITaxon:4890 created_by: jl creation_date: 2010-02-05T10:37:16Z [Term] id: GO:0044342 name: type B pancreatic cell proliferation namespace: biological_process def: "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin." [GOC:jl, GOC:yaf] synonym: "pancreatic B cell proliferation" EXACT [GOC:mah] synonym: "pancreatic beta cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000169 ! type B pancreatic cell relationship: acts_on_population_of CL:0000169 ! type B pancreatic cell created_by: jl creation_date: 2010-08-25T01:44:51Z [Term] id: GO:0044346 name: fibroblast apoptotic process namespace: biological_process def: "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." [CL:0000057, GOC:jl, GOC:mtg_apoptosis, GOC:yaf] synonym: "fibroblast apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000057 ! fibroblast relationship: occurs_in CL:0000057 ! fibroblast created_by: jl creation_date: 2010-09-23T11:33:38Z [Term] id: GO:0044380 name: protein localization to cytoskeleton namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." [GOC:jl] synonym: "protein localisation to cytoskeleton" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005856 ! cytoskeleton relationship: has_target_end_location GO:0005856 ! cytoskeleton created_by: jl creation_date: 2011-12-13T11:43:24Z [Term] id: GO:0044419 name: biological process involved in interspecies interaction between organisms namespace: biological_process def: "Any process evolved to enable an interaction with an organism of a different species." [GOC:cc] subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_pir synonym: "interaction with another species" EXACT [] synonym: "interspecies interaction" EXACT [] synonym: "interspecies interaction between organisms" EXACT [] synonym: "interspecies interaction with other organisms" EXACT [] is_a: GO:0008150 ! biological_process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20191" xsd:anyURI property_value: RO:0002161 NCBITaxon:4895 [Term] id: GO:0044458 name: motile cilium assembly namespace: biological_process alt_id: GO:1903887 def: "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." [GO_REF:0000079, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:19776033, PMID:21129373, ZFIN:dsf] synonym: "motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "motile primary cilium assembly" RELATED [] synonym: "motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:0060271 ! cilium assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0031514 ! motile cilium relationship: results_in_assembly_of GO:0031514 ! motile cilium created_by: krc creation_date: 2015-02-06T17:23:23Z [Term] id: GO:0044550 name: secondary metabolite biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." [GOC:jl] subset: prokaryote_subset synonym: "secondary metabolite biosynthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0019748 ! secondary metabolic process created_by: jl creation_date: 2012-03-29T01:55:18Z [Term] id: GO:0044565 name: dendritic cell proliferation namespace: biological_process def: "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, PMID:18469816] is_a: GO:0032943 ! mononuclear cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000451 ! dendritic cell relationship: acts_on_population_of CL:0000451 ! dendritic cell created_by: jl creation_date: 2012-04-05T04:31:39Z [Term] id: GO:0044566 name: chondrocyte activation namespace: biological_process def: "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." [CL:0000138, GOC:jl] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000138 ! chondrocyte relationship: has_input CL:0000138 ! chondrocyte created_by: jl creation_date: 2012-04-05T04:45:38Z [Term] id: GO:0044703 name: multi-organism reproductive process namespace: biological_process def: "A biological process that directly contributes to the process of producing new individuals, involving another organism." [GOC:jl] subset: goslim_drosophila is_a: GO:0022414 ! reproductive process created_by: jl creation_date: 2012-09-19T15:56:30Z [Term] id: GO:0044706 name: multi-multicellular organism process namespace: biological_process def: "A multicellular organism process which involves another multicellular organism of the same or different species." [GOC:jl] is_a: GO:0032501 ! multicellular organismal process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21459" xsd:anyURI created_by: jl creation_date: 2012-09-19T16:06:16Z [Term] id: GO:0044782 name: cilium organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:jl] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. subset: goslim_drosophila subset: goslim_generic synonym: "microtubule-based flagellum organization" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: results_in_organization_of GO:0005929 ! cilium created_by: jl creation_date: 2013-03-27T15:09:58Z [Term] id: GO:0045026 name: plasma membrane fusion namespace: biological_process alt_id: GO:0006947 def: "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." [GOC:elh, GOC:mtg_muscle] synonym: "cell fusion" BROAD [] synonym: "cell-cell fusion" BROAD [] is_a: GO:0007009 ! plasma membrane organization is_a: GO:0061025 ! membrane fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005886 ! plasma membrane relationship: results_in_fusion_of GO:0005886 ! plasma membrane [Term] id: GO:0045095 name: keratin filament namespace: cellular_component def: "A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins." [ISBN:0716731363] synonym: "acidic keratin" RELATED [] synonym: "basic/neutral keratin" RELATED [] is_a: GO:0005882 ! intermediate filament [Term] id: GO:0045103 name: intermediate filament-based process namespace: biological_process def: "Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins." [GOC:ai] is_a: GO:0009987 ! cellular process [Term] id: GO:0045104 name: intermediate filament cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins." [GOC:ai] synonym: "intermediate filament cytoskeleton organisation" EXACT [] synonym: "intermediate filament cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0007010 ! cytoskeleton organization is_a: GO:0045103 ! intermediate filament-based process intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0045111 ! intermediate filament cytoskeleton relationship: results_in_organization_of GO:0045111 ! intermediate filament cytoskeleton [Term] id: GO:0045109 name: intermediate filament organization namespace: biological_process def: "Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking." [GOC:ai] synonym: "intermediate filament organisation" EXACT [] is_a: GO:0045104 ! intermediate filament cytoskeleton organization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005882 ! intermediate filament relationship: results_in_organization_of GO:0005882 ! intermediate filament [Term] id: GO:0045110 name: intermediate filament bundle assembly namespace: biological_process def: "The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs." [ISBN:0716731363] synonym: "tonofilament assembly" NARROW [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0045109 ! intermediate filament organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_organization_of GO:0005882 ! intermediate filament [Term] id: GO:0045111 name: intermediate filament cytoskeleton namespace: cellular_component def: "Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell." [ISBN:0716731363] is_a: GO:0005856 ! cytoskeleton [Term] id: GO:0045120 name: pronucleus namespace: cellular_component def: "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." [ISBN:0198506732] xref: Wikipedia:Pronucleus is_a: GO:0005634 ! nucleus relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0045132 name: meiotic chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." [GOC:ai, GOC:mah] is_a: GO:0098813 ! nuclear chromosome segregation is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0098813 ! nuclear chromosome segregation intersection_of: part_of GO:0140013 ! meiotic nuclear division relationship: part_of GO:0140013 ! meiotic nuclear division [Term] id: GO:0045137 name: development of primary sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0003006 ! developmental process involved in reproduction relationship: part_of GO:0007275 ! multicellular organism development relationship: part_of GO:0007548 ! sex differentiation [Term] id: GO:0045144 name: meiotic sister chromatid segregation namespace: biological_process def: "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." [GOC:ai, ISBN:0815316194] synonym: "meiosis II, chromosome segregation" EXACT [] is_a: GO:0000819 ! sister chromatid segregation is_a: GO:0045132 ! meiotic chromosome segregation is_a: GO:0070192 ! chromosome organization involved in meiotic cell cycle intersection_of: GO:0000819 ! sister chromatid segregation intersection_of: part_of GO:0007135 ! meiosis II relationship: part_of GO:0007135 ! meiosis II [Term] id: GO:0045165 name: cell fate commitment namespace: biological_process def: "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." [ISBN:0716731185] comment: Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created. is_a: GO:0048869 ! cellular developmental process relationship: part_of GO:0030154 ! cell differentiation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0045168 name: cell-cell signaling involved in cell fate commitment namespace: biological_process def: "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "cell fate commitment, cell-cell signaling" EXACT [] synonym: "cell fate commitment, cell-cell signalling" EXACT [] synonym: "cell-cell signaling during in cell fate commitment" EXACT [] synonym: "cell-cell signaling resulting in cell fate commitment" EXACT [] synonym: "cell-cell signalling during cell fate commitment" EXACT [] synonym: "cell-cell signalling involved in cell fate specification" NARROW [GOC:dph, GOC:tb] synonym: "cell-cell signalling resulting in cell fate commitment" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0045165 ! cell fate commitment relationship: part_of GO:0045165 ! cell fate commitment [Term] id: GO:0045184 name: establishment of protein localization namespace: biological_process def: "The directed movement of a protein to a specific location." [GOC:bf] synonym: "establishment of protein localisation" EXACT [GOC:mah] synonym: "protein positioning" EXACT [] synonym: "protein recruitment" EXACT [] is_a: GO:0008104 ! protein localization is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input CHEBI:36080 ! protein [Term] id: GO:0045196 name: establishment or maintenance of neuroblast polarity namespace: biological_process alt_id: GO:0043339 alt_id: GO:0043342 def: "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mah, GOC:mtg_sensu, PMID:19375318, PMID:20066083] synonym: "establishment and/or maintenance of neuroblast cell polarity" EXACT [] is_a: GO:0007163 ! establishment or maintenance of cell polarity relationship: part_of GO:0055059 ! asymmetric neuroblast division [Term] id: GO:0045200 name: establishment of neuroblast polarity namespace: biological_process alt_id: GO:0043340 alt_id: GO:0043343 def: "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." [GOC:bf, GOC:mtg_sensu] synonym: "establishment of neuroblast cell polarity" EXACT [] is_a: GO:0030010 ! establishment of cell polarity is_a: GO:0045196 ! establishment or maintenance of neuroblast polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000031 ! neuroblast (sensu Vertebrata) relationship: occurs_in CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0045202 name: synapse namespace: cellular_component def: "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." [GOC:aruk, ISBN:0198506732, PMID:24619342, PMID:29383328, PMID:31998110] subset: goslim_agr subset: goslim_drosophila subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: goslim_synapse synonym: "electrotonic synapse" RELATED [NIF_Subcellular:sao1311109124] synonym: "mixed synapse" NARROW [NIF_Subcellular:sao1506103497] synonym: "synaptic junction" EXACT [] xref: NIF_Subcellular:sao914572699 xref: Wikipedia:Chemical_synapse is_a: GO:0030054 ! cell junction relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0045214 name: sarcomere organization namespace: biological_process alt_id: GO:0006938 def: "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:bf] synonym: "sarcomere alignment" EXACT [] synonym: "sarcomere organisation" EXACT [] is_a: GO:0031032 ! actomyosin structure organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030017 ! sarcomere relationship: part_of GO:0030239 ! myofibril assembly relationship: results_in_organization_of GO:0030017 ! sarcomere [Term] id: GO:0045216 name: cell-cell junction organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] synonym: "cell-cell junction assembly and maintenance" EXACT [] synonym: "cell-cell junction biogenesis" RELATED [] synonym: "cell-cell junction organisation" EXACT [GOC:mah] synonym: "intercellular junction assembly and maintenance" EXACT [] is_a: GO:0034330 ! cell junction organization intersection_of: GO:0034330 ! cell junction organization intersection_of: results_in_organization_of GO:0005911 ! cell-cell junction relationship: results_in_organization_of GO:0005911 ! cell-cell junction [Term] id: GO:0045222 name: CD4 biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions." [GOC:go_curators, ISBN:0198506732] synonym: "CD4 anabolism" EXACT [] synonym: "CD4 biosynthesis" EXACT [] synonym: "CD4 formation" EXACT [] synonym: "CD4 synthesis" EXACT [] is_a: GO:0009101 ! glycoprotein biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output PR:000001004 ! CD4 molecule relationship: has_primary_output PR:000001004 ! CD4 molecule [Term] id: GO:0045223 name: regulation of CD4 production namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "regulation of CD4 anabolism" EXACT [] synonym: "regulation of CD4 biosynthesis" EXACT [] synonym: "regulation of CD4 biosynthetic process" EXACT [] synonym: "regulation of CD4 formation" EXACT [] synonym: "regulation of CD4 synthesis" EXACT [] is_a: GO:0010559 ! regulation of glycoprotein biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045222 ! CD4 biosynthetic process relationship: regulates GO:0045222 ! CD4 biosynthetic process [Term] id: GO:0045224 name: positive regulation of CD4 production namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "activation of CD4 biosynthetic process" NARROW [] synonym: "positive regulation of CD4 anabolism" EXACT [] synonym: "positive regulation of CD4 biosynthesis" EXACT [] synonym: "positive regulation of CD4 biosynthetic process" EXACT [] synonym: "positive regulation of CD4 formation" EXACT [] synonym: "positive regulation of CD4 synthesis" EXACT [] synonym: "stimulation of CD4 biosynthetic process" NARROW [] synonym: "up regulation of CD4 biosynthetic process" EXACT [] synonym: "up-regulation of CD4 biosynthetic process" EXACT [] synonym: "upregulation of CD4 biosynthetic process" EXACT [] is_a: GO:0010560 ! positive regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045222 ! CD4 biosynthetic process relationship: positively_regulates GO:0045222 ! CD4 biosynthetic process [Term] id: GO:0045225 name: negative regulation of CD4 production namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." [GOC:go_curators] synonym: "down regulation of CD4 biosynthetic process" EXACT [] synonym: "down-regulation of CD4 biosynthetic process" EXACT [] synonym: "downregulation of CD4 biosynthetic process" EXACT [] synonym: "inhibition of CD4 biosynthetic process" NARROW [] synonym: "negative regulation of CD4 anabolism" EXACT [] synonym: "negative regulation of CD4 biosynthesis" EXACT [] synonym: "negative regulation of CD4 biosynthetic process" EXACT [] synonym: "negative regulation of CD4 formation" EXACT [] synonym: "negative regulation of CD4 synthesis" EXACT [] is_a: GO:0010561 ! negative regulation of glycoprotein biosynthetic process is_a: GO:0045223 ! regulation of CD4 production intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045222 ! CD4 biosynthetic process relationship: negatively_regulates GO:0045222 ! CD4 biosynthetic process [Term] id: GO:0045229 name: external encapsulating structure organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_pir synonym: "external encapsulating structure organisation" EXACT [] synonym: "external encapsulating structure organization and biogenesis" EXACT [GOC:dph, GOC:jl, GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0030312 ! external encapsulating structure relationship: results_in_organization_of GO:0030312 ! external encapsulating structure [Term] id: GO:0045321 name: leukocyte activation namespace: biological_process def: "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." [GOC:add] synonym: "immune cell activation" EXACT [] synonym: "leucocyte activation" EXACT [] xref: Wikipedia:Immunologic_activation is_a: GO:0001775 ! cell activation is_a: GO:0002376 ! immune system process intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000738 ! leukocyte relationship: has_input CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: GO:0045444 name: fat cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." [CL:0000136, GOC:go_curators] synonym: "adipocyte cell differentiation" EXACT [] synonym: "adipocyte differentiation" EXACT [] synonym: "adipogenesis" RELATED [] synonym: "adipose cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000136 ! fat cell relationship: results_in_acquisition_of_features_of CL:0000136 ! fat cell [Term] id: GO:0045445 name: myoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "myoblast cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000056 ! myoblast relationship: part_of GO:0061061 ! muscle structure development relationship: results_in_acquisition_of_features_of CL:0000056 ! myoblast [Term] id: GO:0045446 name: endothelial cell differentiation namespace: biological_process def: "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." [CL:0000115, GOC:go_curators] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000115 ! endothelial cell relationship: part_of GO:0003158 ! endothelium development relationship: results_in_acquisition_of_features_of CL:0000115 ! endothelial cell [Term] id: GO:0045580 name: regulation of T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "regulation of T cell development" RELATED [GOC:add] synonym: "regulation of T lymphocyte differentiation" EXACT [] synonym: "regulation of T-cell differentiation" EXACT [] synonym: "regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0050863 ! regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030217 ! T cell differentiation relationship: regulates GO:0030217 ! T cell differentiation [Term] id: GO:0045581 name: negative regulation of T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "down regulation of T cell differentiation" EXACT [] synonym: "down-regulation of T cell differentiation" EXACT [] synonym: "downregulation of T cell differentiation" EXACT [] synonym: "inhibition of T cell differentiation" NARROW [] synonym: "negative regulation of T cell development" RELATED [GOC:add] synonym: "negative regulation of T lymphocyte differentiation" EXACT [] synonym: "negative regulation of T-cell differentiation" EXACT [] synonym: "negative regulation of T-lymphocyte differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045620 ! negative regulation of lymphocyte differentiation is_a: GO:0050868 ! negative regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030217 ! T cell differentiation relationship: negatively_regulates GO:0030217 ! T cell differentiation [Term] id: GO:0045582 name: positive regulation of T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "activation of T cell differentiation" NARROW [] synonym: "positive regulation of T cell development" RELATED [GOC:add] synonym: "positive regulation of T lymphocyte differentiation" EXACT [] synonym: "positive regulation of T-cell differentiation" EXACT [] synonym: "positive regulation of T-lymphocyte differentiation" EXACT [] synonym: "stimulation of T cell differentiation" NARROW [] synonym: "up regulation of T cell differentiation" EXACT [] synonym: "up-regulation of T cell differentiation" EXACT [] synonym: "upregulation of T cell differentiation" EXACT [] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:0045621 ! positive regulation of lymphocyte differentiation is_a: GO:0050870 ! positive regulation of T cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030217 ! T cell differentiation relationship: positively_regulates GO:0030217 ! T cell differentiation [Term] id: GO:0045595 name: regulation of cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030154 ! cell differentiation relationship: regulates GO:0030154 ! cell differentiation [Term] id: GO:0045596 name: negative regulation of cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "down regulation of cell differentiation" EXACT [] synonym: "down-regulation of cell differentiation" EXACT [] synonym: "downregulation of cell differentiation" EXACT [] synonym: "inhibition of cell differentiation" NARROW [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030154 ! cell differentiation relationship: negatively_regulates GO:0030154 ! cell differentiation [Term] id: GO:0045597 name: positive regulation of cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell differentiation." [GOC:go_curators] synonym: "activation of cell differentiation" NARROW [] synonym: "stimulation of cell differentiation" NARROW [] synonym: "up regulation of cell differentiation" EXACT [] synonym: "up-regulation of cell differentiation" EXACT [] synonym: "upregulation of cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030154 ! cell differentiation relationship: positively_regulates GO:0030154 ! cell differentiation [Term] id: GO:0045598 name: regulation of fat cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "regulation of adipocyte cell differentiation" EXACT [] synonym: "regulation of adipocyte differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045444 ! fat cell differentiation relationship: regulates GO:0045444 ! fat cell differentiation [Term] id: GO:0045599 name: negative regulation of fat cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "down regulation of fat cell differentiation" EXACT [] synonym: "down-regulation of fat cell differentiation" EXACT [] synonym: "downregulation of fat cell differentiation" EXACT [] synonym: "inhibition of fat cell differentiation" NARROW [] synonym: "negative regulation of adipocyte cell differentiation" EXACT [] synonym: "negative regulation of adipocyte differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045444 ! fat cell differentiation relationship: negatively_regulates GO:0045444 ! fat cell differentiation [Term] id: GO:0045600 name: positive regulation of fat cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." [GOC:go_curators] synonym: "activation of fat cell differentiation" NARROW [] synonym: "positive regulation of adipocyte cell differentiation" EXACT [] synonym: "positive regulation of adipocyte differentiation" EXACT [] synonym: "stimulation of fat cell differentiation" NARROW [] synonym: "up regulation of fat cell differentiation" EXACT [] synonym: "up-regulation of fat cell differentiation" EXACT [] synonym: "upregulation of fat cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045598 ! regulation of fat cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045444 ! fat cell differentiation relationship: positively_regulates GO:0045444 ! fat cell differentiation [Term] id: GO:0045601 name: regulation of endothelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045446 ! endothelial cell differentiation relationship: regulates GO:0045446 ! endothelial cell differentiation [Term] id: GO:0045602 name: negative regulation of endothelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "down regulation of endothelial cell differentiation" EXACT [] synonym: "down-regulation of endothelial cell differentiation" EXACT [] synonym: "downregulation of endothelial cell differentiation" EXACT [] synonym: "inhibition of endothelial cell differentiation" NARROW [] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045446 ! endothelial cell differentiation relationship: negatively_regulates GO:0045446 ! endothelial cell differentiation [Term] id: GO:0045603 name: positive regulation of endothelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." [GOC:go_curators] synonym: "activation of endothelial cell differentiation" NARROW [] synonym: "stimulation of endothelial cell differentiation" NARROW [] synonym: "up regulation of endothelial cell differentiation" EXACT [] synonym: "up-regulation of endothelial cell differentiation" EXACT [] synonym: "upregulation of endothelial cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045446 ! endothelial cell differentiation relationship: positively_regulates GO:0045446 ! endothelial cell differentiation [Term] id: GO:0045604 name: regulation of epidermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045682 ! regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009913 ! epidermal cell differentiation relationship: regulates GO:0009913 ! epidermal cell differentiation [Term] id: GO:0045605 name: negative regulation of epidermal cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "down regulation of epidermal cell differentiation" EXACT [] synonym: "down-regulation of epidermal cell differentiation" EXACT [] synonym: "downregulation of epidermal cell differentiation" EXACT [] synonym: "inhibition of epidermal cell differentiation" NARROW [] synonym: "negative regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045683 ! negative regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009913 ! epidermal cell differentiation relationship: negatively_regulates GO:0009913 ! epidermal cell differentiation [Term] id: GO:0045606 name: positive regulation of epidermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." [GOC:go_curators] synonym: "activation of epidermal cell differentiation" NARROW [] synonym: "positive regulation of hypodermal cell differentiation" RELATED [GOC:kmv, GOC:rk] synonym: "stimulation of epidermal cell differentiation" NARROW [] synonym: "up regulation of epidermal cell differentiation" EXACT [] synonym: "up-regulation of epidermal cell differentiation" EXACT [] synonym: "upregulation of epidermal cell differentiation" EXACT [] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0045604 ! regulation of epidermal cell differentiation is_a: GO:0045684 ! positive regulation of epidermis development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009913 ! epidermal cell differentiation relationship: positively_regulates GO:0009913 ! epidermal cell differentiation [Term] id: GO:0045619 name: regulation of lymphocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "regulation of lymphocyte development" RELATED [GOC:add] is_a: GO:0051249 ! regulation of lymphocyte activation is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030098 ! lymphocyte differentiation relationship: regulates GO:0030098 ! lymphocyte differentiation [Term] id: GO:0045620 name: negative regulation of lymphocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "down regulation of lymphocyte differentiation" EXACT [] synonym: "down-regulation of lymphocyte differentiation" EXACT [] synonym: "downregulation of lymphocyte differentiation" EXACT [] synonym: "inhibition of lymphocyte differentiation" NARROW [] synonym: "negative regulation of lymphocyte development" RELATED [GOC:add] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1902106 ! negative regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030098 ! lymphocyte differentiation relationship: negatively_regulates GO:0030098 ! lymphocyte differentiation [Term] id: GO:0045621 name: positive regulation of lymphocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." [GOC:go_curators] comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. synonym: "activation of lymphocyte differentiation" NARROW [] synonym: "positive regulation of lymphocyte development" RELATED [GOC:add] synonym: "stimulation of lymphocyte differentiation" NARROW [] synonym: "up regulation of lymphocyte differentiation" EXACT [] synonym: "up-regulation of lymphocyte differentiation" EXACT [] synonym: "upregulation of lymphocyte differentiation" EXACT [] is_a: GO:0045619 ! regulation of lymphocyte differentiation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1902107 ! positive regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030098 ! lymphocyte differentiation relationship: positively_regulates GO:0030098 ! lymphocyte differentiation [Term] id: GO:0045637 name: regulation of myeloid cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030099 ! myeloid cell differentiation relationship: regulates GO:0030099 ! myeloid cell differentiation [Term] id: GO:0045638 name: negative regulation of myeloid cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "down regulation of myeloid cell differentiation" EXACT [] synonym: "down-regulation of myeloid cell differentiation" EXACT [] synonym: "downregulation of myeloid cell differentiation" EXACT [] synonym: "inhibition of myeloid cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030099 ! myeloid cell differentiation relationship: negatively_regulates GO:0030099 ! myeloid cell differentiation [Term] id: GO:0045639 name: positive regulation of myeloid cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." [GOC:go_curators] synonym: "activation of myeloid cell differentiation" NARROW [] synonym: "stimulation of myeloid cell differentiation" NARROW [] synonym: "up regulation of myeloid cell differentiation" EXACT [] synonym: "up-regulation of myeloid cell differentiation" EXACT [] synonym: "upregulation of myeloid cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030099 ! myeloid cell differentiation relationship: positively_regulates GO:0030099 ! myeloid cell differentiation [Term] id: GO:0045646 name: regulation of erythrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "regulation of RBC differentiation" EXACT [CL:0000232] synonym: "regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030218 ! erythrocyte differentiation relationship: regulates GO:0030218 ! erythrocyte differentiation [Term] id: GO:0045647 name: negative regulation of erythrocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "down regulation of erythrocyte differentiation" EXACT [] synonym: "down-regulation of erythrocyte differentiation" EXACT [] synonym: "downregulation of erythrocyte differentiation" EXACT [] synonym: "inhibition of erythrocyte differentiation" NARROW [] synonym: "negative regulation of RBC differentiation" EXACT [CL:0000232] synonym: "negative regulation of red blood cell differentiation" EXACT [CL:0000232] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030218 ! erythrocyte differentiation relationship: negatively_regulates GO:0030218 ! erythrocyte differentiation [Term] id: GO:0045648 name: positive regulation of erythrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." [GOC:go_curators] synonym: "activation of erythrocyte differentiation" NARROW [] synonym: "positive regulation of RBC differentiation" EXACT [CL:0000232] synonym: "positive regulation of red blood cell differentiation" EXACT [CL:0000232] synonym: "stimulation of erythrocyte differentiation" NARROW [] synonym: "up regulation of erythrocyte differentiation" EXACT [] synonym: "up-regulation of erythrocyte differentiation" EXACT [] synonym: "upregulation of erythrocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045646 ! regulation of erythrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030218 ! erythrocyte differentiation relationship: positively_regulates GO:0030218 ! erythrocyte differentiation [Term] id: GO:0045652 name: regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] is_a: GO:0045637 ! regulation of myeloid cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030219 ! megakaryocyte differentiation relationship: regulates GO:0030219 ! megakaryocyte differentiation [Term] id: GO:0045653 name: negative regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "down regulation of megakaryocyte differentiation" EXACT [] synonym: "down-regulation of megakaryocyte differentiation" EXACT [] synonym: "downregulation of megakaryocyte differentiation" EXACT [] synonym: "inhibition of megakaryocyte differentiation" NARROW [] is_a: GO:0045638 ! negative regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030219 ! megakaryocyte differentiation relationship: negatively_regulates GO:0030219 ! megakaryocyte differentiation [Term] id: GO:0045654 name: positive regulation of megakaryocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." [GOC:go_curators] synonym: "activation of megakaryocyte differentiation" NARROW [] synonym: "stimulation of megakaryocyte differentiation" NARROW [] synonym: "up regulation of megakaryocyte differentiation" EXACT [] synonym: "up-regulation of megakaryocyte differentiation" EXACT [] synonym: "upregulation of megakaryocyte differentiation" EXACT [] is_a: GO:0045639 ! positive regulation of myeloid cell differentiation is_a: GO:0045652 ! regulation of megakaryocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030219 ! megakaryocyte differentiation relationship: positively_regulates GO:0030219 ! megakaryocyte differentiation [Term] id: GO:0045661 name: regulation of myoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045445 ! myoblast differentiation relationship: regulates GO:0045445 ! myoblast differentiation [Term] id: GO:0045662 name: negative regulation of myoblast differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "down regulation of myoblast differentiation" EXACT [] synonym: "down-regulation of myoblast differentiation" EXACT [] synonym: "downregulation of myoblast differentiation" EXACT [] synonym: "inhibition of myoblast differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045445 ! myoblast differentiation relationship: negatively_regulates GO:0045445 ! myoblast differentiation [Term] id: GO:0045663 name: positive regulation of myoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:go_curators, GOC:mtg_muscle] synonym: "activation of myoblast differentiation" NARROW [] synonym: "stimulation of myoblast differentiation" NARROW [] synonym: "up regulation of myoblast differentiation" EXACT [] synonym: "up-regulation of myoblast differentiation" EXACT [] synonym: "upregulation of myoblast differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045661 ! regulation of myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045445 ! myoblast differentiation relationship: positively_regulates GO:0045445 ! myoblast differentiation [Term] id: GO:0045664 name: regulation of neuron differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron differentiation." [GOC:go_curators] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030182 ! neuron differentiation relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: regulates GO:0030182 ! neuron differentiation [Term] id: GO:0045665 name: negative regulation of neuron differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "down regulation of neuron differentiation" EXACT [] synonym: "down-regulation of neuron differentiation" EXACT [] synonym: "downregulation of neuron differentiation" EXACT [] synonym: "inhibition of neuron differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030182 ! neuron differentiation relationship: negatively_regulates GO:0030182 ! neuron differentiation [Term] id: GO:0045666 name: positive regulation of neuron differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron differentiation." [GOC:go_curators] synonym: "activation of neuron differentiation" NARROW [] synonym: "stimulation of neuron differentiation" NARROW [] synonym: "up regulation of neuron differentiation" EXACT [] synonym: "up-regulation of neuron differentiation" EXACT [] synonym: "upregulation of neuron differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030182 ! neuron differentiation relationship: positively_regulates GO:0030182 ! neuron differentiation [Term] id: GO:0045682 name: regulation of epidermis development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "regulation of epidermal development" EXACT [] synonym: "regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008544 ! epidermis development relationship: regulates GO:0008544 ! epidermis development [Term] id: GO:0045683 name: negative regulation of epidermis development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "down regulation of epidermis development" EXACT [] synonym: "down-regulation of epidermis development" EXACT [] synonym: "downregulation of epidermis development" EXACT [] synonym: "inhibition of epidermis development" NARROW [] synonym: "negative regulation of epidermal development" EXACT [] synonym: "negative regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008544 ! epidermis development relationship: negatively_regulates GO:0008544 ! epidermis development [Term] id: GO:0045684 name: positive regulation of epidermis development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epidermis development." [GOC:go_curators] synonym: "activation of epidermis development" NARROW [] synonym: "positive regulation of epidermal development" EXACT [] synonym: "positive regulation of hypodermis development" RELATED [GOC:kmv, GOC:rk] synonym: "stimulation of epidermis development" NARROW [] synonym: "up regulation of epidermis development" EXACT [] synonym: "up-regulation of epidermis development" EXACT [] synonym: "upregulation of epidermis development" EXACT [] is_a: GO:0045682 ! regulation of epidermis development is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008544 ! epidermis development relationship: positively_regulates GO:0008544 ! epidermis development [Term] id: GO:0045685 name: regulation of glial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "regulation of glia cell differentiation" EXACT [] synonym: "regulation of neuroglia differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010001 ! glial cell differentiation relationship: regulates GO:0010001 ! glial cell differentiation [Term] id: GO:0045686 name: negative regulation of glial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "down regulation of glial cell differentiation" EXACT [] synonym: "down-regulation of glial cell differentiation" EXACT [] synonym: "downregulation of glial cell differentiation" EXACT [] synonym: "inhibition of glial cell differentiation" NARROW [] synonym: "negative regulation of glia cell differentiation" EXACT [] synonym: "negative regulation of neuroglia differentiation" EXACT [] is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010001 ! glial cell differentiation relationship: negatively_regulates GO:0010001 ! glial cell differentiation [Term] id: GO:0045687 name: positive regulation of glial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." [GOC:go_curators] synonym: "activation of glial cell differentiation" NARROW [] synonym: "positive regulation of glia cell differentiation" EXACT [] synonym: "positive regulation of neuroglia differentiation" EXACT [] synonym: "stimulation of glial cell differentiation" NARROW [] synonym: "up regulation of glial cell differentiation" EXACT [] synonym: "up-regulation of glial cell differentiation" EXACT [] synonym: "upregulation of glial cell differentiation" EXACT [] is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010001 ! glial cell differentiation relationship: positively_regulates GO:0010001 ! glial cell differentiation [Term] id: GO:0045700 name: regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903353 ! regulation of nucleus organization is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007289 ! spermatid nucleus differentiation relationship: regulates GO:0007289 ! spermatid nucleus differentiation [Term] id: GO:0045701 name: negative regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "down regulation of spermatid nuclear differentiation" EXACT [] synonym: "down-regulation of spermatid nuclear differentiation" EXACT [] synonym: "downregulation of spermatid nuclear differentiation" EXACT [] synonym: "inhibition of spermatid nuclear differentiation" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007289 ! spermatid nucleus differentiation relationship: negatively_regulates GO:0007289 ! spermatid nucleus differentiation [Term] id: GO:0045702 name: positive regulation of spermatid nuclear differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." [GOC:go_curators] synonym: "activation of spermatid nuclear differentiation" NARROW [] synonym: "stimulation of spermatid nuclear differentiation" NARROW [] synonym: "up regulation of spermatid nuclear differentiation" EXACT [] synonym: "up-regulation of spermatid nuclear differentiation" EXACT [] synonym: "upregulation of spermatid nuclear differentiation" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0045700 ! regulation of spermatid nuclear differentiation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007289 ! spermatid nucleus differentiation relationship: positively_regulates GO:0007289 ! spermatid nucleus differentiation [Term] id: GO:0045719 name: negative regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen biosynthetic process" EXACT [] synonym: "down-regulation of glycogen biosynthetic process" EXACT [] synonym: "downregulation of glycogen biosynthetic process" EXACT [] synonym: "inhibition of glycogen biosynthetic process" NARROW [] synonym: "negative regulation of glycogen anabolism" EXACT [] synonym: "negative regulation of glycogen biosynthesis" EXACT [] synonym: "negative regulation of glycogen formation" EXACT [] synonym: "negative regulation of glycogen synthesis" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005978 ! glycogen biosynthetic process relationship: negatively_regulates GO:0005978 ! glycogen biosynthetic process [Term] id: GO:0045721 name: negative regulation of gluconeogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "down regulation of gluconeogenesis" EXACT [] synonym: "down-regulation of gluconeogenesis" EXACT [] synonym: "downregulation of gluconeogenesis" EXACT [] synonym: "inhibition of gluconeogenesis" NARROW [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006094 ! gluconeogenesis relationship: negatively_regulates GO:0006094 ! gluconeogenesis [Term] id: GO:0045722 name: positive regulation of gluconeogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." [GOC:go_curators] synonym: "activation of gluconeogenesis" NARROW [] synonym: "stimulation of gluconeogenesis" NARROW [] synonym: "up regulation of gluconeogenesis" EXACT [] synonym: "up-regulation of gluconeogenesis" EXACT [] synonym: "upregulation of gluconeogenesis" EXACT [] is_a: GO:0006111 ! regulation of gluconeogenesis is_a: GO:0010907 ! positive regulation of glucose metabolic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006094 ! gluconeogenesis relationship: positively_regulates GO:0006094 ! gluconeogenesis [Term] id: GO:0045724 name: positive regulation of cilium assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." [GOC:cilia, GOC:go_curators] synonym: "activation of cilium assembly" NARROW [] synonym: "positive regulation of flagellum assembly" BROAD [] synonym: "positive regulation of flagellum biogenesis" RELATED [GOC:mah] synonym: "stimulation of cilium assembly" NARROW [] synonym: "up regulation of cilium assembly" EXACT [] synonym: "up-regulation of cilium assembly" EXACT [] synonym: "upregulation of cilium assembly" EXACT [] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902117 ! positive regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060271 ! cilium assembly relationship: positively_regulates GO:0060271 ! cilium assembly [Term] id: GO:0045725 name: positive regulation of glycogen biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." [GOC:go_curators] synonym: "activation of glycogen biosynthetic process" NARROW [] synonym: "positive regulation of glycogen anabolism" EXACT [] synonym: "positive regulation of glycogen biosynthesis" EXACT [] synonym: "positive regulation of glycogen formation" EXACT [] synonym: "positive regulation of glycogen synthesis" EXACT [] synonym: "stimulation of glycogen biosynthetic process" NARROW [] synonym: "up regulation of glycogen biosynthetic process" EXACT [] synonym: "up-regulation of glycogen biosynthetic process" EXACT [] synonym: "upregulation of glycogen biosynthetic process" EXACT [] is_a: GO:0005979 ! regulation of glycogen biosynthetic process is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005978 ! glycogen biosynthetic process relationship: positively_regulates GO:0005978 ! glycogen biosynthetic process [Term] id: GO:0045727 name: positive regulation of translation namespace: biological_process alt_id: GO:0045946 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of protein biosynthetic process" NARROW [] synonym: "positive regulation of protein anabolism" EXACT [] synonym: "positive regulation of protein biosynthesis" EXACT [] synonym: "positive regulation of protein biosynthetic process" EXACT [GOC:tb] synonym: "positive regulation of protein formation" EXACT [] synonym: "positive regulation of protein synthesis" EXACT [] synonym: "stimulation of protein biosynthetic process" NARROW [] synonym: "up regulation of protein biosynthetic process" EXACT [] synonym: "up-regulation of protein biosynthetic process" EXACT [] synonym: "upregulation of protein biosynthetic process" EXACT [] is_a: GO:0006417 ! regulation of translation is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0010628 ! positive regulation of gene expression is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0034250 ! positive regulation of amide metabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006412 ! translation relationship: positively_regulates GO:0006412 ! translation [Term] id: GO:0045732 name: positive regulation of protein catabolic process namespace: biological_process alt_id: GO:1903364 alt_id: GO:2000600 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:go_curators] synonym: "activation of cellular protein breakdown" NARROW [GOC:TermGenie] synonym: "activation of cellular protein catabolic process" NARROW [GOC:TermGenie] synonym: "activation of cellular protein catabolism" NARROW [GOC:TermGenie] synonym: "activation of cellular protein degradation" NARROW [GOC:TermGenie] synonym: "activation of protein catabolic process" NARROW [] synonym: "positive regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein catabolic process" EXACT [] synonym: "positive regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of cyclin breakdown" NARROW [GOC:obol] synonym: "positive regulation of cyclin catabolic process" NARROW [] synonym: "positive regulation of cyclin catabolism" NARROW [GOC:obol] synonym: "positive regulation of cyclin degradation" NARROW [GOC:obol] synonym: "positive regulation of degradation of cyclin" NARROW [GOC:obol] synonym: "positive regulation of protein breakdown" EXACT [] synonym: "positive regulation of protein catabolism" EXACT [] synonym: "positive regulation of protein degradation" EXACT [] synonym: "stimulation of protein catabolic process" NARROW [] synonym: "up regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein catabolic process" EXACT [] synonym: "up-regulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein catabolic process" EXACT [] synonym: "upregulation of cellular protein breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0051247 ! positive regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030163 ! protein catabolic process relationship: positively_regulates GO:0030163 ! protein catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0045733 name: acetate catabolic process namespace: biological_process alt_id: GO:0019663 def: "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "acetate breakdown" EXACT [] synonym: "acetate catabolism" EXACT [] synonym: "acetate degradation" EXACT [] synonym: "homoacetate catabolic process" RELATED [] is_a: GO:0006083 ! acetate metabolic process is_a: GO:0072329 ! monocarboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:30089 ! acetate relationship: has_primary_input CHEBI:30089 ! acetate [Term] id: GO:0045734 name: regulation of acetate catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." [GOC:go_curators] synonym: "regulation of acetate breakdown" EXACT [] synonym: "regulation of acetate catabolism" EXACT [] synonym: "regulation of acetate degradation" EXACT [] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031329 ! regulation of cellular catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045733 ! acetate catabolic process relationship: regulates GO:0045733 ! acetate catabolic process [Term] id: GO:0045753 name: negative regulation of acetate catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "down regulation of acetate catabolic process" EXACT [] synonym: "down-regulation of acetate catabolic process" EXACT [] synonym: "downregulation of acetate catabolic process" EXACT [] synonym: "inhibition of acetate catabolic process" NARROW [] synonym: "negative regulation of acetate breakdown" EXACT [] synonym: "negative regulation of acetate catabolism" EXACT [] synonym: "negative regulation of acetate degradation" EXACT [] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045733 ! acetate catabolic process relationship: negatively_regulates GO:0045733 ! acetate catabolic process [Term] id: GO:0045754 name: positive regulation of acetate catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." [GOC:go_curators] synonym: "activation of acetate catabolic process" NARROW [] synonym: "positive regulation of acetate breakdown" EXACT [] synonym: "positive regulation of acetate catabolism" EXACT [] synonym: "positive regulation of acetate degradation" EXACT [] synonym: "stimulation of acetate catabolic process" NARROW [] synonym: "up regulation of acetate catabolic process" EXACT [] synonym: "up-regulation of acetate catabolic process" EXACT [] synonym: "upregulation of acetate catabolic process" EXACT [] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0045734 ! regulation of acetate catabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045733 ! acetate catabolic process relationship: positively_regulates GO:0045733 ! acetate catabolic process [Term] id: GO:0045759 name: negative regulation of action potential namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "down regulation of action potential" EXACT [] synonym: "down-regulation of action potential" EXACT [] synonym: "downregulation of action potential" EXACT [] synonym: "inhibition of action potential" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001508 ! action potential relationship: negatively_regulates GO:0001508 ! action potential [Term] id: GO:0045760 name: positive regulation of action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:go_curators] synonym: "activation of action potential" NARROW [] synonym: "stimulation of action potential" NARROW [] synonym: "up regulation of action potential" EXACT [] synonym: "up-regulation of action potential" EXACT [] synonym: "upregulation of action potential" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001508 ! action potential relationship: positively_regulates GO:0001508 ! action potential [Term] id: GO:0045763 name: negative regulation of cellular amino acid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "down regulation of amino acid metabolic process" EXACT [] synonym: "down-regulation of amino acid metabolic process" EXACT [] synonym: "downregulation of amino acid metabolic process" EXACT [] synonym: "inhibition of amino acid metabolic process" NARROW [] synonym: "negative regulation of amino acid metabolism" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006520 ! amino acid metabolic process relationship: negatively_regulates GO:0006520 ! amino acid metabolic process [Term] id: GO:0045764 name: positive regulation of amino acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." [GOC:go_curators] synonym: "activation of amino acid metabolic process" NARROW [] synonym: "positive regulation of amino acid metabolism" EXACT [] synonym: "positive regulation of cellular amino acid metabolic process" EXACT [] synonym: "stimulation of amino acid metabolic process" NARROW [] synonym: "up regulation of amino acid metabolic process" EXACT [] synonym: "up-regulation of amino acid metabolic process" EXACT [] synonym: "upregulation of amino acid metabolic process" EXACT [] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006520 ! amino acid metabolic process relationship: positively_regulates GO:0006520 ! amino acid metabolic process [Term] id: GO:0045765 name: regulation of angiogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of angiogenesis." [GOC:go_curators] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001525 ! angiogenesis relationship: regulates GO:0001525 ! angiogenesis [Term] id: GO:0045766 name: positive regulation of angiogenesis namespace: biological_process def: "Any process that activates or increases angiogenesis." [GOC:go_curators] synonym: "activation of angiogenesis" NARROW [] synonym: "stimulation of angiogenesis" NARROW [] synonym: "up regulation of angiogenesis" EXACT [] synonym: "up-regulation of angiogenesis" EXACT [] synonym: "upregulation of angiogenesis" EXACT [] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:1904018 ! positive regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001525 ! angiogenesis relationship: positively_regulates GO:0001525 ! angiogenesis [Term] id: GO:0045769 name: negative regulation of asymmetric cell division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "down regulation of asymmetric cell division" EXACT [] synonym: "down-regulation of asymmetric cell division" EXACT [] synonym: "downregulation of asymmetric cell division" EXACT [] synonym: "inhibition of asymmetric cell division" NARROW [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051782 ! negative regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008356 ! asymmetric cell division relationship: negatively_regulates GO:0008356 ! asymmetric cell division [Term] id: GO:0045770 name: positive regulation of asymmetric cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." [GOC:go_curators] synonym: "activation of asymmetric cell division" NARROW [] synonym: "stimulation of asymmetric cell division" NARROW [] synonym: "up regulation of asymmetric cell division" EXACT [] synonym: "up-regulation of asymmetric cell division" EXACT [] synonym: "upregulation of asymmetric cell division" EXACT [] is_a: GO:0009786 ! regulation of asymmetric cell division is_a: GO:0051781 ! positive regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008356 ! asymmetric cell division relationship: positively_regulates GO:0008356 ! asymmetric cell division [Term] id: GO:0045778 name: positive regulation of ossification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." [GOC:go_curators] synonym: "activation of ossification" NARROW [] synonym: "positive regulation of bone biosynthesis" EXACT [] synonym: "positive regulation of bone formation" EXACT [] synonym: "stimulation of ossification" NARROW [] synonym: "up regulation of ossification" EXACT [] synonym: "up-regulation of ossification" EXACT [] synonym: "upregulation of ossification" EXACT [] is_a: GO:0030278 ! regulation of ossification is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001503 ! ossification relationship: positively_regulates GO:0001503 ! ossification [Term] id: GO:0045785 name: positive regulation of cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell adhesion." [GOC:go_curators] synonym: "activation of cell adhesion" NARROW [] synonym: "stimulation of cell adhesion" NARROW [] synonym: "up regulation of cell adhesion" EXACT [] synonym: "up-regulation of cell adhesion" EXACT [] synonym: "upregulation of cell adhesion" EXACT [] is_a: GO:0030155 ! regulation of cell adhesion is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007155 ! cell adhesion relationship: positively_regulates GO:0007155 ! cell adhesion [Term] id: GO:0045786 name: negative regulation of cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through cell cycle" EXACT [] synonym: "down-regulation of progression through cell cycle" EXACT [] synonym: "downregulation of progression through cell cycle" EXACT [] synonym: "inhibition of progression through cell cycle" NARROW [] synonym: "negative regulation of cell cycle progression" EXACT [] synonym: "negative regulation of progression through cell cycle" EXACT [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007049 ! cell cycle relationship: negatively_regulates GO:0007049 ! cell cycle [Term] id: GO:0045787 name: positive regulation of cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the cell cycle." [GOC:go_curators] synonym: "activation of progression through cell cycle" NARROW [] synonym: "positive regulation of cell cycle progression" EXACT [] synonym: "positive regulation of progression through cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through cell cycle" NARROW [] synonym: "up regulation of progression through cell cycle" EXACT [] synonym: "up-regulation of progression through cell cycle" EXACT [] synonym: "upregulation of progression through cell cycle" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051726 ! regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007049 ! cell cycle relationship: positively_regulates GO:0007049 ! cell cycle [Term] id: GO:0045818 name: negative regulation of glycogen catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "down regulation of glycogen catabolic process" EXACT [] synonym: "down-regulation of glycogen catabolic process" EXACT [] synonym: "downregulation of glycogen catabolic process" EXACT [] synonym: "inhibition of glycogen catabolic process" NARROW [] synonym: "negative regulation of glycogen breakdown" EXACT [] synonym: "negative regulation of glycogen catabolism" EXACT [] synonym: "negative regulation of glycogen degradation" EXACT [] synonym: "negative regulation of glycogenolysis" EXACT [GOC:sl] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0070874 ! negative regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005980 ! glycogen catabolic process relationship: negatively_regulates GO:0005980 ! glycogen catabolic process [Term] id: GO:0045819 name: positive regulation of glycogen catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." [GOC:go_curators] synonym: "activation of glycogen catabolic process" NARROW [] synonym: "positive regulation of glycogen breakdown" EXACT [] synonym: "positive regulation of glycogen catabolism" EXACT [] synonym: "positive regulation of glycogen degradation" EXACT [] synonym: "positive regulation of glycogenolysis" EXACT [GOC:sl] synonym: "stimulation of glycogen catabolic process" NARROW [] synonym: "up regulation of glycogen catabolic process" EXACT [] synonym: "up-regulation of glycogen catabolic process" EXACT [] synonym: "upregulation of glycogen catabolic process" EXACT [] is_a: GO:0005981 ! regulation of glycogen catabolic process is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0070875 ! positive regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005980 ! glycogen catabolic process relationship: positively_regulates GO:0005980 ! glycogen catabolic process [Term] id: GO:0045822 name: negative regulation of heart contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "down regulation of heart contraction" EXACT [] synonym: "down-regulation of heart contraction" EXACT [] synonym: "downregulation of heart contraction" EXACT [] synonym: "inhibition of heart contraction" NARROW [] synonym: "negative regulation of cardiac contraction" RELATED [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903523 ! negative regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060047 ! heart contraction relationship: negatively_regulates GO:0060047 ! heart contraction [Term] id: GO:0045823 name: positive regulation of heart contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of heart contraction." [GOC:go_curators] synonym: "activation of heart contraction" NARROW [] synonym: "positive regulation of cardiac contraction" EXACT [] synonym: "stimulation of heart contraction" NARROW [] synonym: "up regulation of heart contraction" EXACT [] synonym: "up-regulation of heart contraction" EXACT [] synonym: "upregulation of heart contraction" EXACT [] is_a: GO:0008016 ! regulation of heart contraction is_a: GO:1903524 ! positive regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060047 ! heart contraction relationship: positively_regulates GO:0060047 ! heart contraction [Term] id: GO:0045833 name: negative regulation of lipid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "down regulation of lipid metabolic process" EXACT [] synonym: "down-regulation of lipid metabolic process" EXACT [] synonym: "downregulation of lipid metabolic process" EXACT [] synonym: "inhibition of lipid metabolic process" NARROW [] synonym: "negative regulation of lipid metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006629 ! lipid metabolic process relationship: negatively_regulates GO:0006629 ! lipid metabolic process [Term] id: GO:0045834 name: positive regulation of lipid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." [GOC:go_curators] synonym: "activation of lipid metabolic process" NARROW [] synonym: "positive regulation of lipid metabolism" EXACT [] synonym: "stimulation of lipid metabolic process" NARROW [] synonym: "up regulation of lipid metabolic process" EXACT [] synonym: "up-regulation of lipid metabolic process" EXACT [] synonym: "upregulation of lipid metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006629 ! lipid metabolic process relationship: positively_regulates GO:0006629 ! lipid metabolic process [Term] id: GO:0045835 name: negative regulation of meiotic nuclear division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "down regulation of meiosis" EXACT [] synonym: "down-regulation of meiosis" EXACT [] synonym: "downregulation of meiosis" EXACT [] synonym: "inhibition of meiosis" NARROW [] synonym: "negative regulation of meiosis" EXACT [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0140013 ! meiotic nuclear division relationship: negatively_regulates GO:0140013 ! meiotic nuclear division [Term] id: GO:0045836 name: positive regulation of meiotic nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of meiosis." [GOC:go_curators] synonym: "activation of meiosis" NARROW [] synonym: "positive regulation of meiosis" EXACT [] synonym: "stimulation of meiosis" NARROW [] synonym: "up regulation of meiosis" EXACT [] synonym: "up-regulation of meiosis" EXACT [] synonym: "upregulation of meiosis" EXACT [] is_a: GO:0040020 ! regulation of meiotic nuclear division is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0140013 ! meiotic nuclear division relationship: positively_regulates GO:0140013 ! meiotic nuclear division [Term] id: GO:0045839 name: negative regulation of mitotic nuclear division namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of mitosis" EXACT [] synonym: "down-regulation of mitosis" EXACT [] synonym: "downregulation of mitosis" EXACT [] synonym: "inhibition of mitosis" NARROW [] synonym: "negative regulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0045930 ! negative regulation of mitotic cell cycle is_a: GO:0051784 ! negative regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0140014 ! mitotic nuclear division relationship: negatively_regulates GO:0140014 ! mitotic nuclear division [Term] id: GO:0045840 name: positive regulation of mitotic nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitosis." [GOC:go_curators] synonym: "activation of mitosis" NARROW [] synonym: "mitogenic activity" NARROW [] synonym: "positive regulation of mitosis" EXACT [] synonym: "stimulation of mitosis" NARROW [] synonym: "up regulation of mitosis" EXACT [] synonym: "up-regulation of mitosis" EXACT [] synonym: "upregulation of mitosis" EXACT [] is_a: GO:0007088 ! regulation of mitotic nuclear division is_a: GO:0051785 ! positive regulation of nuclear division is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0140014 ! mitotic nuclear division relationship: positively_regulates GO:0140014 ! mitotic nuclear division [Term] id: GO:0045843 name: negative regulation of striated muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "down regulation of striated muscle development" EXACT [] synonym: "down-regulation of striated muscle development" EXACT [] synonym: "downregulation of striated muscle development" EXACT [] synonym: "inhibition of striated muscle development" NARROW [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048635 ! negative regulation of muscle organ development is_a: GO:1901862 ! negative regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014706 ! striated muscle tissue development relationship: negatively_regulates GO:0014706 ! striated muscle tissue development [Term] id: GO:0045844 name: positive regulation of striated muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle development." [GOC:go_curators] synonym: "activation of striated muscle development" NARROW [] synonym: "stimulation of striated muscle development" NARROW [] synonym: "up regulation of striated muscle development" EXACT [] synonym: "up-regulation of striated muscle development" EXACT [] synonym: "upregulation of striated muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development is_a: GO:0048636 ! positive regulation of muscle organ development is_a: GO:1901863 ! positive regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014706 ! striated muscle tissue development relationship: positively_regulates GO:0014706 ! striated muscle tissue development [Term] id: GO:0045900 name: negative regulation of translational elongation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "down regulation of translational elongation" EXACT [] synonym: "down-regulation of translational elongation" EXACT [] synonym: "downregulation of translational elongation" EXACT [] synonym: "inhibition of translational elongation" NARROW [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006414 ! translational elongation relationship: negatively_regulates GO:0006414 ! translational elongation [Term] id: GO:0045901 name: positive regulation of translational elongation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational elongation." [GOC:go_curators] synonym: "activation of translational elongation" NARROW [] synonym: "stimulation of translational elongation" NARROW [] synonym: "up regulation of translational elongation" EXACT [] synonym: "up-regulation of translational elongation" EXACT [] synonym: "upregulation of translational elongation" EXACT [] is_a: GO:0006448 ! regulation of translational elongation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006414 ! translational elongation relationship: positively_regulates GO:0006414 ! translational elongation [Term] id: GO:0045904 name: negative regulation of translational termination namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "down regulation of translational termination" EXACT [] synonym: "down-regulation of translational termination" EXACT [] synonym: "downregulation of translational termination" EXACT [] synonym: "inhibition of translational termination" NARROW [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0017148 ! negative regulation of translation is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006415 ! translational termination relationship: negatively_regulates GO:0006415 ! translational termination [Term] id: GO:0045905 name: positive regulation of translational termination namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational termination." [GOC:go_curators] synonym: "activation of translational termination" NARROW [] synonym: "stimulation of translational termination" NARROW [] synonym: "up regulation of translational termination" EXACT [] synonym: "up-regulation of translational termination" EXACT [] synonym: "upregulation of translational termination" EXACT [] is_a: GO:0006449 ! regulation of translational termination is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006415 ! translational termination relationship: positively_regulates GO:0006415 ! translational termination [Term] id: GO:0045912 name: negative regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "down regulation of carbohydrate metabolic process" EXACT [] synonym: "down-regulation of carbohydrate metabolic process" EXACT [] synonym: "downregulation of carbohydrate metabolic process" EXACT [] synonym: "inhibition of carbohydrate metabolic process" NARROW [] synonym: "negative regulation of carbohydrate metabolism" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009892 ! negative regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005975 ! carbohydrate metabolic process relationship: negatively_regulates GO:0005975 ! carbohydrate metabolic process [Term] id: GO:0045913 name: positive regulation of carbohydrate metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." [GOC:go_curators] synonym: "activation of carbohydrate metabolic process" NARROW [] synonym: "positive regulation of carbohydrate metabolism" EXACT [] synonym: "stimulation of carbohydrate metabolic process" NARROW [] synonym: "up regulation of carbohydrate metabolic process" EXACT [] synonym: "up-regulation of carbohydrate metabolic process" EXACT [] synonym: "upregulation of carbohydrate metabolic process" EXACT [] is_a: GO:0006109 ! regulation of carbohydrate metabolic process is_a: GO:0009893 ! positive regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005975 ! carbohydrate metabolic process relationship: positively_regulates GO:0005975 ! carbohydrate metabolic process [Term] id: GO:0045914 name: negative regulation of catecholamine metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] synonym: "down regulation of catecholamine metabolic process" EXACT [] synonym: "down-regulation of catecholamine metabolic process" EXACT [] synonym: "downregulation of catecholamine metabolic process" EXACT [] synonym: "inhibition of catecholamine metabolic process" NARROW [] synonym: "negative regulation of catecholamine metabolism" EXACT [] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0042069 ! regulation of catecholamine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006584 ! catecholamine metabolic process relationship: negatively_regulates GO:0006584 ! catecholamine metabolic process [Term] id: GO:0045915 name: positive regulation of catecholamine metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." [GOC:go_curators] synonym: "activation of catecholamine metabolic process" NARROW [] synonym: "positive regulation of catecholamine metabolism" EXACT [] synonym: "stimulation of catecholamine metabolic process" NARROW [] synonym: "up regulation of catecholamine metabolic process" EXACT [] synonym: "up-regulation of catecholamine metabolic process" EXACT [] synonym: "upregulation of catecholamine metabolic process" EXACT [] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0042069 ! regulation of catecholamine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006584 ! catecholamine metabolic process relationship: positively_regulates GO:0006584 ! catecholamine metabolic process [Term] id: GO:0045920 name: negative regulation of exocytosis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "down regulation of exocytosis" EXACT [] synonym: "down-regulation of exocytosis" EXACT [] synonym: "downregulation of exocytosis" EXACT [] synonym: "inhibition of exocytosis" NARROW [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006887 ! exocytosis relationship: negatively_regulates GO:0006887 ! exocytosis [Term] id: GO:0045921 name: positive regulation of exocytosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exocytosis." [GOC:go_curators] synonym: "activation of exocytosis" NARROW [] synonym: "stimulation of exocytosis" NARROW [] synonym: "up regulation of exocytosis" EXACT [] synonym: "up-regulation of exocytosis" EXACT [] synonym: "upregulation of exocytosis" EXACT [] is_a: GO:0017157 ! regulation of exocytosis is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006887 ! exocytosis relationship: positively_regulates GO:0006887 ! exocytosis [Term] id: GO:0045926 name: negative regulation of growth namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "down regulation of growth" EXACT [] synonym: "down-regulation of growth" EXACT [] synonym: "downregulation of growth" EXACT [] synonym: "inhibition of growth" NARROW [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0040007 ! growth relationship: negatively_regulates GO:0040007 ! growth [Term] id: GO:0045927 name: positive regulation of growth namespace: biological_process def: "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." [GOC:go_curators] synonym: "activation of growth" NARROW [] synonym: "stimulation of growth" NARROW [] synonym: "up regulation of growth" EXACT [] synonym: "up-regulation of growth" EXACT [] synonym: "upregulation of growth" EXACT [] is_a: GO:0040008 ! regulation of growth is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0040007 ! growth relationship: positively_regulates GO:0040007 ! growth [Term] id: GO:0045930 name: negative regulation of mitotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "down regulation of progression through mitotic cell cycle" EXACT [] synonym: "down-regulation of progression through mitotic cell cycle" EXACT [] synonym: "downregulation of progression through mitotic cell cycle" EXACT [] synonym: "inhibition of progression through mitotic cell cycle" NARROW [] synonym: "negative regulation of mitotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045786 ! negative regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000278 ! mitotic cell cycle relationship: negatively_regulates GO:0000278 ! mitotic cell cycle [Term] id: GO:0045931 name: positive regulation of mitotic cell cycle namespace: biological_process def: "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] synonym: "activation of progression through mitotic cell cycle" NARROW [] synonym: "positive regulation of mitotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through mitotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through mitotic cell cycle" NARROW [] synonym: "up regulation of progression through mitotic cell cycle" EXACT [] synonym: "up-regulation of progression through mitotic cell cycle" EXACT [] synonym: "upregulation of progression through mitotic cell cycle" EXACT [] is_a: GO:0007346 ! regulation of mitotic cell cycle is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000278 ! mitotic cell cycle relationship: positively_regulates GO:0000278 ! mitotic cell cycle [Term] id: GO:0045932 name: negative regulation of muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "down regulation of muscle contraction" EXACT [] synonym: "down-regulation of muscle contraction" EXACT [] synonym: "downregulation of muscle contraction" EXACT [] synonym: "inhibition of muscle contraction" NARROW [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006936 ! muscle contraction relationship: negatively_regulates GO:0006936 ! muscle contraction [Term] id: GO:0045933 name: positive regulation of muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle contraction." [GOC:go_curators] synonym: "activation of muscle contraction" NARROW [] synonym: "stimulation of muscle contraction" NARROW [] synonym: "up regulation of muscle contraction" EXACT [] synonym: "up-regulation of muscle contraction" EXACT [] synonym: "upregulation of muscle contraction" EXACT [] is_a: GO:0006937 ! regulation of muscle contraction is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006936 ! muscle contraction relationship: positively_regulates GO:0006936 ! muscle contraction [Term] id: GO:0045934 name: negative regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process relationship: negatively_regulates GO:0006139 ! nucleobase-containing compound metabolic process [Term] id: GO:0045935 name: positive regulation of nucleobase-containing compound metabolic process namespace: biological_process def: "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." [GOC:go_curators] synonym: "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" RELATED [GOC:dph, GOC:tb] synonym: "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" EXACT [] synonym: "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" NARROW [] synonym: "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] synonym: "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process relationship: positively_regulates GO:0006139 ! nucleobase-containing compound metabolic process [Term] id: GO:0045936 name: negative regulation of phosphate metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "down regulation of phosphate metabolic process" EXACT [] synonym: "down-regulation of phosphate metabolic process" EXACT [] synonym: "downregulation of phosphate metabolic process" EXACT [] synonym: "inhibition of phosphate metabolic process" NARROW [] synonym: "negative regulation of phosphate metabolism" EXACT [] is_a: GO:0010563 ! negative regulation of phosphorus metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process relationship: negatively_regulates GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0045937 name: positive regulation of phosphate metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." [GOC:go_curators] synonym: "activation of phosphate metabolic process" NARROW [] synonym: "positive regulation of phosphate metabolism" EXACT [] synonym: "stimulation of phosphate metabolic process" NARROW [] synonym: "up regulation of phosphate metabolic process" EXACT [] synonym: "up-regulation of phosphate metabolic process" EXACT [] synonym: "upregulation of phosphate metabolic process" EXACT [] is_a: GO:0010562 ! positive regulation of phosphorus metabolic process is_a: GO:0019220 ! regulation of phosphate metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process relationship: positively_regulates GO:0006796 ! phosphate-containing compound metabolic process [Term] id: GO:0045939 name: negative regulation of steroid metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "down regulation of steroid metabolic process" EXACT [] synonym: "down-regulation of steroid metabolic process" EXACT [] synonym: "downregulation of steroid metabolic process" EXACT [] synonym: "inhibition of steroid metabolic process" NARROW [] synonym: "negative regulation of steroid metabolism" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008202 ! steroid metabolic process relationship: negatively_regulates GO:0008202 ! steroid metabolic process [Term] id: GO:0045940 name: positive regulation of steroid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." [GOC:go_curators] synonym: "activation of steroid metabolic process" NARROW [] synonym: "positive regulation of steroid metabolism" EXACT [] synonym: "stimulation of steroid metabolic process" NARROW [] synonym: "up regulation of steroid metabolic process" EXACT [] synonym: "up-regulation of steroid metabolic process" EXACT [] synonym: "upregulation of steroid metabolic process" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008202 ! steroid metabolic process relationship: positively_regulates GO:0008202 ! steroid metabolic process [Term] id: GO:0045947 name: negative regulation of translational initiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "down regulation of translational initiation" EXACT [] synonym: "down-regulation of translational initiation" EXACT [] synonym: "downregulation of translational initiation" EXACT [] synonym: "inhibition of translational initiation" NARROW [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0017148 ! negative regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006413 ! translational initiation relationship: negatively_regulates GO:0006413 ! translational initiation [Term] id: GO:0045948 name: positive regulation of translational initiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of translational initiation." [GOC:go_curators] synonym: "activation of translational initiation" NARROW [] synonym: "stimulation of translational initiation" NARROW [] synonym: "up regulation of translational initiation" EXACT [] synonym: "up-regulation of translational initiation" EXACT [] synonym: "upregulation of translational initiation" EXACT [] is_a: GO:0006446 ! regulation of translational initiation is_a: GO:0045727 ! positive regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006413 ! translational initiation relationship: positively_regulates GO:0006413 ! translational initiation [Term] id: GO:0045986 name: negative regulation of smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "down regulation of smooth muscle contraction" EXACT [] synonym: "down-regulation of smooth muscle contraction" EXACT [] synonym: "downregulation of smooth muscle contraction" EXACT [] synonym: "inhibition of smooth muscle contraction" NARROW [] synonym: "smooth muscle relaxation" RELATED [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006939 ! smooth muscle contraction relationship: negatively_regulates GO:0006939 ! smooth muscle contraction [Term] id: GO:0045987 name: positive regulation of smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." [GOC:go_curators] synonym: "activation of smooth muscle contraction" NARROW [] synonym: "stimulation of smooth muscle contraction" NARROW [] synonym: "up regulation of smooth muscle contraction" EXACT [] synonym: "up-regulation of smooth muscle contraction" EXACT [] synonym: "upregulation of smooth muscle contraction" EXACT [] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006939 ! smooth muscle contraction relationship: positively_regulates GO:0006939 ! smooth muscle contraction [Term] id: GO:0045988 name: negative regulation of striated muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "down regulation of striated muscle contraction" EXACT [] synonym: "down-regulation of striated muscle contraction" EXACT [] synonym: "downregulation of striated muscle contraction" EXACT [] synonym: "inhibition of striated muscle contraction" NARROW [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045932 ! negative regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006941 ! striated muscle contraction relationship: negatively_regulates GO:0006941 ! striated muscle contraction [Term] id: GO:0045989 name: positive regulation of striated muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." [GOC:go_curators] synonym: "activation of striated muscle contraction" NARROW [] synonym: "stimulation of striated muscle contraction" NARROW [] synonym: "up regulation of striated muscle contraction" EXACT [] synonym: "up-regulation of striated muscle contraction" EXACT [] synonym: "upregulation of striated muscle contraction" EXACT [] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0045933 ! positive regulation of muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006941 ! striated muscle contraction relationship: positively_regulates GO:0006941 ! striated muscle contraction [Term] id: GO:0045992 name: negative regulation of embryonic development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." [GOC:go_curators] synonym: "down regulation of embryonic development" EXACT [] synonym: "down-regulation of embryonic development" EXACT [] synonym: "downregulation of embryonic development" EXACT [] synonym: "inhibition of embryonic development" NARROW [] is_a: GO:0045995 ! regulation of embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009790 ! embryo development relationship: negatively_regulates GO:0009790 ! embryo development [Term] id: GO:0045995 name: regulation of embryonic development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic development." [GOC:go_curators] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009790 ! embryo development relationship: regulates GO:0009790 ! embryo development [Term] id: GO:0046013 name: regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "regulation of resting T cell proliferation" EXACT [] synonym: "regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "regulation of T-cell homeostatic proliferation" EXACT [] synonym: "regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042129 ! regulation of T cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001777 ! T cell homeostatic proliferation relationship: regulates GO:0001777 ! T cell homeostatic proliferation [Term] id: GO:0046014 name: negative regulation of T cell homeostatic proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." [GOC:go_curators] synonym: "down regulation of T cell homeostatic proliferation" EXACT [] synonym: "down-regulation of T cell homeostatic proliferation" EXACT [] synonym: "downregulation of T cell homeostatic proliferation" EXACT [] synonym: "inhibition of T cell homeostatic proliferation" NARROW [] synonym: "negative regulation of resting T cell proliferation" EXACT [] synonym: "negative regulation of T lymphocyte homeostatic proliferation" EXACT [] synonym: "negative regulation of T-cell homeostatic proliferation" EXACT [] synonym: "negative regulation of T-lymphocyte homeostatic proliferation" EXACT [] is_a: GO:0042130 ! negative regulation of T cell proliferation is_a: GO:0046013 ! regulation of T cell homeostatic proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001777 ! T cell homeostatic proliferation relationship: negatively_regulates GO:0001777 ! T cell homeostatic proliferation [Term] id: GO:0046112 name: nucleobase biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase anabolism" EXACT [] synonym: "nucleobase biosynthesis" EXACT [] synonym: "nucleobase formation" EXACT [] synonym: "nucleobase synthesis" EXACT [] is_a: GO:0009112 ! nucleobase metabolic process is_a: GO:0018130 ! heterocycle biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:18282 ! nucleobase relationship: has_primary_output CHEBI:18282 ! nucleobase [Term] id: GO:0046113 name: nucleobase catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." [GOC:ai] synonym: "nucleobase breakdown" EXACT [] synonym: "nucleobase catabolism" EXACT [] synonym: "nucleobase degradation" EXACT [] is_a: GO:0009112 ! nucleobase metabolic process is_a: GO:0046700 ! heterocycle catabolic process is_a: GO:1901361 ! organic cyclic compound catabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:18282 ! nucleobase relationship: has_primary_input CHEBI:18282 ! nucleobase [Term] id: GO:0046189 name: phenol-containing compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." [GOC:ai] synonym: "phenol-containing compound anabolism" EXACT [] synonym: "phenol-containing compound biosynthesis" EXACT [] synonym: "phenol-containing compound formation" EXACT [] synonym: "phenol-containing compound synthesis" EXACT [] is_a: GO:0018958 ! phenol-containing compound metabolic process is_a: GO:0019438 ! aromatic compound biosynthetic process is_a: GO:1901362 ! organic cyclic compound biosynthetic process is_a: GO:1901617 ! organic hydroxy compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33853 ! phenols relationship: has_primary_output CHEBI:33853 ! phenols [Term] id: GO:0046219 name: indolalkylamine biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." [GOC:curators] synonym: "indolalkylamine anabolism" EXACT [] synonym: "indolalkylamine biosynthesis" EXACT [] synonym: "indolalkylamine formation" EXACT [] synonym: "indolalkylamine synthesis" EXACT [] is_a: GO:0006586 ! indolalkylamine metabolic process is_a: GO:0042401 ! biogenic amine biosynthetic process is_a: GO:0042435 ! indole-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:38631 ! aminoalkylindole relationship: has_primary_output CHEBI:38631 ! aminoalkylindole [Term] id: GO:0046364 name: monosaccharide biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide anabolism" EXACT [] synonym: "monosaccharide biosynthesis" EXACT [] synonym: "monosaccharide formation" EXACT [] synonym: "monosaccharide synthesis" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016051 ! carbohydrate biosynthetic process is_a: GO:0044283 ! small molecule biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35381 ! monosaccharide relationship: has_primary_output CHEBI:35381 ! monosaccharide [Term] id: GO:0046365 name: monosaccharide catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." [ISBN:0198506732] synonym: "monosaccharide breakdown" EXACT [] synonym: "monosaccharide catabolism" EXACT [] synonym: "monosaccharide degradation" EXACT [] is_a: GO:0005996 ! monosaccharide metabolic process is_a: GO:0016052 ! carbohydrate catabolic process is_a: GO:0044282 ! small molecule catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35381 ! monosaccharide relationship: has_primary_input CHEBI:35381 ! monosaccharide [Term] id: GO:0046394 name: carboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid anabolism" EXACT [] synonym: "carboxylic acid biosynthesis" EXACT [] synonym: "carboxylic acid formation" EXACT [] synonym: "carboxylic acid synthesis" EXACT [] is_a: GO:0016053 ! organic acid biosynthetic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:29067 ! carboxylic acid anion relationship: has_primary_output CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0046395 name: carboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." [ISBN:0198506732] synonym: "carboxylic acid breakdown" EXACT [] synonym: "carboxylic acid catabolism" EXACT [] synonym: "carboxylic acid degradation" EXACT [] is_a: GO:0016054 ! organic acid catabolic process is_a: GO:0019752 ! carboxylic acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0046483 name: heterocycle metabolic process namespace: biological_process def: "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [ISBN:0198506732] subset: goslim_pir synonym: "heterocycle metabolism" EXACT [] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound relationship: has_primary_input_or_output CHEBI:5686 ! heterocyclic compound [Term] id: GO:0046530 name: photoreceptor cell differentiation namespace: biological_process alt_id: GO:0007467 def: "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." [GOC:ai, ISBN:0198506732] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000210 ! photoreceptor cell relationship: results_in_acquisition_of_features_of CL:0000210 ! photoreceptor cell [Term] id: GO:0046532 name: regulation of photoreceptor cell differentiation namespace: biological_process alt_id: GO:0045673 def: "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046530 ! photoreceptor cell differentiation relationship: regulates GO:0046530 ! photoreceptor cell differentiation [Term] id: GO:0046533 name: negative regulation of photoreceptor cell differentiation namespace: biological_process alt_id: GO:0045674 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "down regulation of photoreceptor cell differentiation" EXACT [] synonym: "down regulation of photoreceptor differentiation" EXACT [] synonym: "down-regulation of photoreceptor cell differentiation" EXACT [] synonym: "down-regulation of photoreceptor differentiation" EXACT [] synonym: "downregulation of photoreceptor cell differentiation" EXACT [] synonym: "downregulation of photoreceptor differentiation" EXACT [] synonym: "inhibition of photoreceptor cell differentiation" NARROW [] synonym: "inhibition of photoreceptor differentiation" NARROW [] synonym: "negative regulation of photoreceptor differentiation" EXACT [] is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046530 ! photoreceptor cell differentiation relationship: negatively_regulates GO:0046530 ! photoreceptor cell differentiation [Term] id: GO:0046534 name: positive regulation of photoreceptor cell differentiation namespace: biological_process alt_id: GO:0045675 def: "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." [GOC:go_curators] synonym: "activation of photoreceptor cell differentiation" NARROW [] synonym: "activation of photoreceptor differentiation" NARROW [] synonym: "positive regulation of photoreceptor differentiation" EXACT [] synonym: "stimulation of photoreceptor cell differentiation" NARROW [] synonym: "stimulation of photoreceptor differentiation" NARROW [] synonym: "up regulation of photoreceptor cell differentiation" EXACT [] synonym: "up regulation of photoreceptor differentiation" EXACT [] synonym: "up-regulation of photoreceptor cell differentiation" EXACT [] synonym: "up-regulation of photoreceptor differentiation" EXACT [] synonym: "upregulation of photoreceptor cell differentiation" EXACT [] synonym: "upregulation of photoreceptor differentiation" EXACT [] is_a: GO:0045666 ! positive regulation of neuron differentiation is_a: GO:0046532 ! regulation of photoreceptor cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046530 ! photoreceptor cell differentiation relationship: positively_regulates GO:0046530 ! photoreceptor cell differentiation [Term] id: GO:0046545 name: development of primary female sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: part_of GO:0046660 ! female sex differentiation [Term] id: GO:0046546 name: development of primary male sexual characteristics namespace: biological_process def: "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." [GOC:ai] is_a: GO:0045137 ! development of primary sexual characteristics relationship: part_of GO:0046661 ! male sex differentiation [Term] id: GO:0046548 name: retinal rod cell development namespace: biological_process def: "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000604 ! retinal rod cell relationship: part_of GO:0060221 ! retinal rod cell differentiation relationship: results_in_development_of CL:0000604 ! retinal rod cell [Term] id: GO:0046549 name: retinal cone cell development namespace: biological_process def: "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." [ISBN:0198506732] is_a: GO:0042462 ! eye photoreceptor cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000573 ! retinal cone cell relationship: part_of GO:0042670 ! retinal cone cell differentiation relationship: results_in_development_of CL:0000573 ! retinal cone cell [Term] id: GO:0046620 name: regulation of organ growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035265 ! organ growth relationship: regulates GO:0035265 ! organ growth [Term] id: GO:0046621 name: negative regulation of organ growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048640 ! negative regulation of developmental growth is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035265 ! organ growth relationship: negatively_regulates GO:0035265 ! organ growth [Term] id: GO:0046622 name: positive regulation of organ growth namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." [GOC:bf, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035265 ! organ growth relationship: positively_regulates GO:0035265 ! organ growth [Term] id: GO:0046649 name: lymphocyte activation namespace: biological_process def: "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." [GOC:mgi_curators, ISBN:0781735149] is_a: GO:0045321 ! leukocyte activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000542 ! lymphocyte relationship: has_input CL:0000542 ! lymphocyte [Term] id: GO:0046651 name: lymphocyte proliferation namespace: biological_process def: "The expansion of a lymphocyte population by cell division." [GOC:ai] is_a: GO:0032943 ! mononuclear cell proliferation is_a: GO:0046649 ! lymphocyte activation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000542 ! lymphocyte relationship: acts_on_population_of CL:0000542 ! lymphocyte [Term] id: GO:0046660 name: female sex differentiation namespace: biological_process def: "The establishment of the sex of a female organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0046661 name: male sex differentiation namespace: biological_process def: "The establishment of the sex of a male organism by physical differentiation." [GOC:bf] is_a: GO:0007548 ! sex differentiation relationship: part_of GO:0007275 ! multicellular organism development [Term] id: GO:0046666 name: retinal cell programmed cell death namespace: biological_process def: "Programmed cell death that occurs in the developing retina." [GOC:bf] synonym: "programmed cell death, retina cells" EXACT [] synonym: "programmed cell death, retinal cells" EXACT [] synonym: "retina cell programmed cell death" EXACT [] synonym: "retina programmed cell death" EXACT [] synonym: "retinal programmed cell death" EXACT [] is_a: GO:0010623 ! programmed cell death involved in cell development relationship: part_of GO:0048592 ! eye morphogenesis [Term] id: GO:0046667 name: compound eye retinal cell programmed cell death namespace: biological_process def: "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." [PMID:12006672] is_a: GO:0046666 ! retinal cell programmed cell death intersection_of: GO:0046666 ! retinal cell programmed cell death intersection_of: results_in_maturation_of UBERON:0000018 ! compound eye relationship: part_of GO:0001745 ! compound eye morphogenesis relationship: results_in_maturation_of UBERON:0000018 ! compound eye [Term] id: GO:0046668 name: regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043067 ! regulation of programmed cell death is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046666 ! retinal cell programmed cell death relationship: regulates GO:0046666 ! retinal cell programmed cell death [Term] id: GO:0046669 name: regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "regulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046668 ! regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046667 ! compound eye retinal cell programmed cell death relationship: regulates GO:0046667 ! compound eye retinal cell programmed cell death [Term] id: GO:0046670 name: positive regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "activation of retinal programmed cell death" NARROW [] synonym: "positive regulation of retinal programmed cell death" EXACT [GOC:tb] synonym: "stimulation of retinal programmed cell death" NARROW [] synonym: "up regulation of retinal programmed cell death" EXACT [] synonym: "up-regulation of retinal programmed cell death" EXACT [] synonym: "upregulation of retinal programmed cell death" EXACT [] is_a: GO:0043068 ! positive regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046666 ! retinal cell programmed cell death relationship: positively_regulates GO:0046666 ! retinal cell programmed cell death [Term] id: GO:0046671 name: negative regulation of retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." [GOC:ai, GOC:tb] synonym: "down regulation of retinal programmed cell death" EXACT [] synonym: "down-regulation of retinal programmed cell death" EXACT [] synonym: "downregulation of retinal programmed cell death" EXACT [] synonym: "inhibition of retinal programmed cell death" NARROW [] synonym: "negative regulation of retinal programmed cell death" EXACT [GOC:tb] is_a: GO:0043069 ! negative regulation of programmed cell death is_a: GO:0046668 ! regulation of retinal cell programmed cell death is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046666 ! retinal cell programmed cell death relationship: negatively_regulates GO:0046666 ! retinal cell programmed cell death [Term] id: GO:0046672 name: positive regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "activation of retinal cell programmed cell death" BROAD [] synonym: "positive regulation of retinal cell programmed cell death" BROAD [] synonym: "stimulation of retinal cell programmed cell death" BROAD [] synonym: "up regulation of retinal cell programmed cell death" BROAD [] synonym: "up-regulation of retinal cell programmed cell death" BROAD [] synonym: "upregulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046670 ! positive regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death relationship: positively_regulates GO:0046667 ! compound eye retinal cell programmed cell death [Term] id: GO:0046673 name: negative regulation of compound eye retinal cell programmed cell death namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." [GOC:ai] synonym: "down regulation of retinal cell programmed cell death" BROAD [] synonym: "down-regulation of retinal cell programmed cell death" BROAD [] synonym: "downregulation of retinal cell programmed cell death" BROAD [] synonym: "inhibition of retinal cell programmed cell death" BROAD [] synonym: "negative regulation of retina cell programmed cell death" BROAD [] synonym: "negative regulation of retinal cell programmed cell death" BROAD [] is_a: GO:0046669 ! regulation of compound eye retinal cell programmed cell death is_a: GO:0046671 ! negative regulation of retinal cell programmed cell death intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death relationship: negatively_regulates GO:0046667 ! compound eye retinal cell programmed cell death [Term] id: GO:0046676 name: negative regulation of insulin secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin." [GOC:ai] synonym: "down regulation of insulin secretion" EXACT [] synonym: "down-regulation of insulin secretion" EXACT [] synonym: "downregulation of insulin secretion" EXACT [] synonym: "inhibition of insulin secretion" NARROW [] is_a: GO:0050709 ! negative regulation of protein secretion is_a: GO:0050796 ! regulation of insulin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030073 ! insulin secretion relationship: negatively_regulates GO:0030073 ! insulin secretion [Term] id: GO:0046681 name: response to carbamate namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." [ISBN:0721662544] synonym: "carbamate resistance" RELATED [] synonym: "carbamate susceptibility/resistance" RELATED [] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:0017085 ! response to insecticide is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:13941 ! carbamate relationship: has_input CHEBI:13941 ! carbamate [Term] id: GO:0046700 name: heterocycle catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." [GOC:ai] synonym: "heterocycle breakdown" EXACT [] synonym: "heterocycle catabolism" EXACT [] synonym: "heterocycle degradation" EXACT [] is_a: GO:0044248 ! cellular catabolic process is_a: GO:0046483 ! heterocycle metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:5686 ! heterocyclic compound relationship: has_primary_input CHEBI:5686 ! heterocyclic compound [Term] id: GO:0046716 name: muscle cell cellular homeostasis namespace: biological_process def: "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." [GOC:mah, PMID:3091429, PMID:7781901] synonym: "muscle fiber maintenance" NARROW [GOC:dph, GOC:tb] synonym: "muscle homeostasis" RELATED [GOC:dph] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: occurs_in CL:0000187 ! muscle cell relationship: occurs_in CL:0000187 ! muscle cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI property_value: RO:0002161 NCBITaxon:4751 [Term] id: GO:0046717 name: acid secretion namespace: biological_process def: "The controlled release of acid by a cell or a tissue." [GOC:ai] is_a: GO:0046903 ! secretion [Term] id: GO:0046785 name: microtubule polymerization namespace: biological_process def: "The addition of tubulin heterodimers to one or both ends of a microtubule." [GOC:ai, GOC:go_curators] synonym: "microtubule assembly" EXACT [] synonym: "microtubule formation" RELATED [] is_a: GO:0031109 ! microtubule polymerization or depolymerization is_a: GO:0051258 ! protein polymerization is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005874 ! microtubule relationship: results_in_assembly_of GO:0005874 ! microtubule relationship: starts_with GO:0007020 ! microtubule nucleation [Term] id: GO:0046873 name: metal ion transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of metal ions from one side of a membrane to the other." [GOC:ai] synonym: "heavy metal ion porter activity" NARROW [] synonym: "heavy metal ion transporter activity" NARROW [] synonym: "heavy metal ion:hydrogen symporter activity" NARROW [] synonym: "heavy metal-exporting ATPase activity" NARROW [] synonym: "high affinity metal ion uptake transporter activity" NARROW [] synonym: "low affinity metal ion uptake transporter activity" NARROW [] is_a: GO:0008324 ! monoatomic cation transmembrane transporter activity is_a: GO:0022890 ! inorganic cation transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:25213 ! metal cation relationship: has_primary_input CHEBI:25213 ! metal cation relationship: part_of GO:0030001 ! metal ion transport [Term] id: GO:0046879 name: hormone secretion namespace: biological_process def: "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." [ISBN:0198506732] is_a: GO:0009914 ! hormone transport is_a: GO:0023061 ! signal release [Term] id: GO:0046883 name: regulation of hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0010817 ! regulation of hormone levels is_a: GO:0023051 ! regulation of signaling is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046879 ! hormone secretion relationship: regulates GO:0046879 ! hormone secretion [Term] id: GO:0046887 name: positive regulation of hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "activation of hormone secretion" NARROW [] synonym: "stimulation of hormone secretion" NARROW [] synonym: "up regulation of hormone secretion" EXACT [] synonym: "up-regulation of hormone secretion" EXACT [] synonym: "upregulation of hormone secretion" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046879 ! hormone secretion relationship: positively_regulates GO:0046879 ! hormone secretion [Term] id: GO:0046888 name: negative regulation of hormone secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." [GOC:ai] synonym: "down regulation of hormone secretion" EXACT [] synonym: "down-regulation of hormone secretion" EXACT [] synonym: "downregulation of hormone secretion" EXACT [] synonym: "inhibition of hormone secretion" NARROW [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0046883 ! regulation of hormone secretion is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046879 ! hormone secretion relationship: negatively_regulates GO:0046879 ! hormone secretion [Term] id: GO:0046889 name: positive regulation of lipid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "activation of lipid biosynthetic process" NARROW [] synonym: "positive regulation of lipid anabolism" EXACT [] synonym: "positive regulation of lipid biosynthesis" EXACT [] synonym: "positive regulation of lipid formation" EXACT [] synonym: "positive regulation of lipid synthesis" EXACT [] synonym: "positive regulation of lipogenesis" EXACT [GOC:sl] synonym: "stimulation of lipid biosynthetic process" NARROW [] synonym: "up regulation of lipid biosynthetic process" EXACT [] synonym: "up-regulation of lipid biosynthetic process" EXACT [] synonym: "upregulation of lipid biosynthetic process" EXACT [] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008610 ! lipid biosynthetic process relationship: positively_regulates GO:0008610 ! lipid biosynthetic process [Term] id: GO:0046890 name: regulation of lipid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "regulation of lipid anabolism" EXACT [] synonym: "regulation of lipid biosynthesis" EXACT [] synonym: "regulation of lipid formation" EXACT [] synonym: "regulation of lipid synthesis" EXACT [] synonym: "regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008610 ! lipid biosynthetic process relationship: regulates GO:0008610 ! lipid biosynthetic process [Term] id: GO:0046903 name: secretion namespace: biological_process def: "The controlled release of a substance by a cell or a tissue." [GOC:ai] subset: goslim_pir is_a: GO:0006810 ! transport [Term] id: GO:0046907 name: intracellular transport namespace: biological_process alt_id: GO:1902582 def: "The directed movement of substances within a cell." [GOC:ai] synonym: "single organism intracellular transport" RELATED [GOC:TermGenie] synonym: "single-organism intracellular transport" RELATED [] is_a: GO:0006810 ! transport is_a: GO:0051641 ! cellular localization is_a: GO:0051649 ! establishment of localization in cell intersection_of: GO:0006810 ! transport intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure relationship: occurs_in GO:0005622 ! intracellular anatomical structure created_by: jl creation_date: 2013-12-18T14:04:50Z [Term] id: GO:0046928 name: regulation of neurotransmitter secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." [GOC:ai] is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0051588 ! regulation of neurotransmitter transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007269 ! neurotransmitter secretion relationship: regulates GO:0007269 ! neurotransmitter secretion [Term] id: GO:0046929 name: negative regulation of neurotransmitter secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." [GOC:ai] synonym: "conotoxin activity" NARROW [] synonym: "down regulation of neurotransmitter secretion" EXACT [] synonym: "down-regulation of neurotransmitter secretion" EXACT [] synonym: "downregulation of neurotransmitter secretion" EXACT [] synonym: "inhibition of neurotransmitter secretion" NARROW [] is_a: GO:0046928 ! regulation of neurotransmitter secretion is_a: GO:0051589 ! negative regulation of neurotransmitter transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007269 ! neurotransmitter secretion relationship: negatively_regulates GO:0007269 ! neurotransmitter secretion [Term] id: GO:0046942 name: carboxylic acid transport namespace: biological_process def: "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] is_a: GO:0015711 ! organic anion transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion [Term] id: GO:0046943 name: carboxylic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." [GOC:ai] xref: Reactome:R-HSA-390347 "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane" is_a: GO:0008514 ! organic anion transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: has_primary_input CHEBI:29067 ! carboxylic acid anion relationship: part_of GO:1905039 ! carboxylic acid transmembrane transport [Term] id: GO:0047496 name: vesicle transport along microtubule namespace: biological_process def: "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." [GOC:ecd, GOC:rl] synonym: "microtubule-based vesicle localization" EXACT [GOC:rl] is_a: GO:0072384 ! organelle transport along microtubule is_a: GO:0099518 ! vesicle cytoskeletal trafficking intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0031982 ! vesicle intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0048048 name: embryonic eye morphogenesis namespace: biological_process def: "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0048592 ! eye morphogenesis [Term] id: GO:0048066 name: developmental pigmentation namespace: biological_process def: "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." [ISBN:0582227089] synonym: "pigmentation during development" RELATED [] is_a: GO:0043473 ! pigmentation [Term] id: GO:0048070 name: regulation of developmental pigmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "regulation of pigmentation during development" EXACT [GOC:dph, GOC:tb] is_a: GO:0120305 ! regulation of pigmentation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048066 ! developmental pigmentation relationship: regulates GO:0048066 ! developmental pigmentation [Term] id: GO:0048086 name: negative regulation of developmental pigmentation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "down regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "down-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "downregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "inhibition of pigmentation" NARROW [] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048519 ! negative regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048066 ! developmental pigmentation relationship: negatively_regulates GO:0048066 ! developmental pigmentation [Term] id: GO:0048087 name: positive regulation of developmental pigmentation namespace: biological_process def: "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." [GOC:dph, GOC:jid, GOC:tb] synonym: "activation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] synonym: "stimulation of developmental pigmentation" NARROW [GOC:dph, GOC:tb] synonym: "up regulation of developmental pigmentation" EXACT [GOC:dph] synonym: "up-regulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of developmental pigmentation" EXACT [GOC:dph, GOC:tb] is_a: GO:0048070 ! regulation of developmental pigmentation is_a: GO:0048518 ! positive regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048066 ! developmental pigmentation relationship: positively_regulates GO:0048066 ! developmental pigmentation [Term] id: GO:0048103 name: somatic stem cell division namespace: biological_process def: "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." [GOC:jid, ISBN:0582227089] synonym: "somatic stem cell renewal" EXACT [] is_a: GO:0017145 ! stem cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000723 ! somatic stem cell relationship: has_input CL:0000723 ! somatic stem cell [Term] id: GO:0048132 name: female germ-line stem cell asymmetric division namespace: biological_process alt_id: GO:0048141 def: "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." [GOC:jid, GOC:mtg_sensu] synonym: "female germ-line stem cell renewal" EXACT [] is_a: GO:0098728 ! germline stem cell asymmetric division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_input CL:0000022 ! female germ line stem cell relationship: has_input CL:0000022 ! female germ line stem cell relationship: in_taxon NCBITaxon:6656 {all_only="true"} ! Arthropoda relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of GO:0048477 ! oogenesis [Term] id: GO:0048137 name: spermatocyte division namespace: biological_process def: "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids." [GOC:jid, GOC:pr, ISBN:0879694238] synonym: "spermatocyte cell division" EXACT [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000017 ! spermatocyte relationship: has_input CL:0000017 ! spermatocyte relationship: part_of GO:0007283 ! spermatogenesis [Term] id: GO:0048144 name: fibroblast proliferation namespace: biological_process def: "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." [GOC:jid] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000057 ! fibroblast relationship: acts_on_population_of CL:0000057 ! fibroblast [Term] id: GO:0048145 name: regulation of fibroblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048144 ! fibroblast proliferation relationship: regulates GO:0048144 ! fibroblast proliferation [Term] id: GO:0048146 name: positive regulation of fibroblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "activation of fibroblast proliferation" NARROW [] synonym: "stimulation of fibroblast proliferation" NARROW [] synonym: "up regulation of fibroblast proliferation" EXACT [] synonym: "up-regulation of fibroblast proliferation" EXACT [] synonym: "upregulation of fibroblast proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048144 ! fibroblast proliferation relationship: positively_regulates GO:0048144 ! fibroblast proliferation [Term] id: GO:0048147 name: negative regulation of fibroblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." [GOC:jid] synonym: "down regulation of fibroblast proliferation" EXACT [] synonym: "down-regulation of fibroblast proliferation" EXACT [] synonym: "downregulation of fibroblast proliferation" EXACT [] synonym: "inhibition of fibroblast proliferation" NARROW [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048145 ! regulation of fibroblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048144 ! fibroblast proliferation relationship: negatively_regulates GO:0048144 ! fibroblast proliferation [Term] id: GO:0048193 name: Golgi vesicle transport namespace: biological_process def: "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." [GOC:jid, ISBN:0716731363, PMID:10219233] subset: goslim_yeast synonym: "Golgi-derived vesicle transport" RELATED [] is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_to_from_or_in GO:0005798 ! Golgi-associated vesicle relationship: results_in_transport_to_from_or_in GO:0005798 ! Golgi-associated vesicle [Term] id: GO:0048199 name: vesicle targeting, to, from or within Golgi namespace: biological_process def: "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "dictyosome vesicle targeting" NARROW [] synonym: "Golgi vesicle targeting" EXACT [] synonym: "vesicle targeting, to, from or within dictyosome" NARROW [] is_a: GO:0006903 ! vesicle targeting intersection_of: GO:0006903 ! vesicle targeting intersection_of: has_primary_input GO:0005798 ! Golgi-associated vesicle intersection_of: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus relationship: has_primary_input GO:0005798 ! Golgi-associated vesicle relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: results_in_transport_to_from_or_in GO:0005794 ! Golgi apparatus [Term] id: GO:0048209 name: regulation of vesicle targeting, to, from or within Golgi namespace: biological_process def: "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." [GOC:jid, GOC:mah, ISBN:0716731363, PMID:10219233] synonym: "regulation of Golgi vesicle targeting" EXACT [] is_a: GO:0060341 ! regulation of cellular localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi relationship: regulates GO:0048199 ! vesicle targeting, to, from or within Golgi [Term] id: GO:0048232 name: male gamete generation namespace: biological_process def: "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." [GOC:dph, GOC:jid] is_a: GO:0007276 ! gamete generation [Term] id: GO:0048240 name: sperm capacitation namespace: biological_process def: "A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium." [GOC:jid, ISBN:978-3-642-58301-8, PMID:11820818] comment: Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract. synonym: "sperm activation" RELATED [PMID:23180860] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0048469 ! cell maturation relationship: part_of GO:0007286 ! spermatid development [Term] id: GO:0048243 name: norepinephrine secretion namespace: biological_process def: "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." [GOC:ef, GOC:jid] synonym: "noradrenaline secretion" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0023061 ! signal release is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) [Term] id: GO:0048251 name: elastic fiber assembly namespace: biological_process def: "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." [GOC:jid, PMID:10841810, PMID:12615674] synonym: "elastic fibre assembly" EXACT [] synonym: "elastin fiber assembly" EXACT [GOC:BHF] synonym: "elastin fibre assembly" EXACT [GOC:BHF] is_a: GO:0085029 ! extracellular matrix assembly is_a: GO:0097435 ! supramolecular fiber organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0071953 ! elastic fiber relationship: results_in_assembly_of GO:0071953 ! elastic fiber [Term] id: GO:0048280 name: vesicle fusion with Golgi apparatus namespace: biological_process def: "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." [GOC:jid] is_a: GO:0006906 ! vesicle fusion is_a: GO:0007030 ! Golgi organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005794 ! Golgi apparatus intersection_of: results_in_fusion_of GO:0031982 ! vesicle relationship: part_of GO:0048193 ! Golgi vesicle transport relationship: results_in_fusion_of GO:0005794 ! Golgi apparatus relationship: results_in_fusion_of GO:0031982 ! vesicle [Term] id: GO:0048284 name: organelle fusion namespace: biological_process def: "The creation of a single organelle from two or more organelles." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0043226 ! organelle relationship: results_in_fusion_of GO:0043226 ! organelle [Term] id: GO:0048285 name: organelle fission namespace: biological_process def: "The creation of two or more organelles by division of one organelle." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fission_of GO:0043226 ! organelle relationship: results_in_fission_of GO:0043226 ! organelle [Term] id: GO:0048288 name: nuclear membrane fusion involved in karyogamy namespace: biological_process def: "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." [GOC:jid] synonym: "nuclear membrane fusion during karyogamy" RELATED [GOC:dph, GOC:tb] is_a: GO:0000740 ! nuclear membrane fusion intersection_of: GO:0000740 ! nuclear membrane fusion intersection_of: part_of GO:0000741 ! karyogamy relationship: part_of GO:0000741 ! karyogamy [Term] id: GO:0048308 name: organelle inheritance namespace: biological_process def: "The partitioning of organelles between daughter cells at cell division." [GOC:jid] subset: goslim_pir subset: goslim_yeast is_a: GO:0006996 ! organelle organization [Term] id: GO:0048313 name: Golgi inheritance namespace: biological_process def: "The partitioning of Golgi apparatus between daughter cells at cell division." [GOC:jid, PMID:12851069] synonym: "Golgi apparatus inheritance" EXACT [] synonym: "Golgi division" EXACT [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi partitioning" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:0048308 ! organelle inheritance intersection_of: GO:0048308 ! organelle inheritance intersection_of: results_in_distribution_of GO:0005794 ! Golgi apparatus relationship: results_in_distribution_of GO:0005794 ! Golgi apparatus [Term] id: GO:0048318 name: axial mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003068 ! axial mesoderm relationship: results_in_development_of UBERON:0003068 ! axial mesoderm [Term] id: GO:0048319 name: axial mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the axial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003068 ! axial mesoderm relationship: part_of GO:0048318 ! axial mesoderm development relationship: results_in_morphogenesis_of UBERON:0003068 ! axial mesoderm [Term] id: GO:0048320 name: axial mesoderm formation namespace: biological_process def: "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003068 ! axial mesoderm relationship: part_of GO:0048319 ! axial mesoderm morphogenesis relationship: results_in_formation_of UBERON:0003068 ! axial mesoderm [Term] id: GO:0048332 name: mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000926 ! mesoderm relationship: part_of GO:0007498 ! mesoderm development relationship: results_in_morphogenesis_of UBERON:0000926 ! mesoderm [Term] id: GO:0048333 name: mesodermal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." [GOC:dgh] synonym: "mesoderm cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000222 ! mesodermal cell relationship: part_of GO:0001707 ! mesoderm formation relationship: results_in_acquisition_of_features_of CL:0000222 ! mesodermal cell [Term] id: GO:0048339 name: paraxial mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." [GOC:dgh] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003077 ! paraxial mesoderm relationship: results_in_development_of UBERON:0003077 ! paraxial mesoderm [Term] id: GO:0048340 name: paraxial mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003077 ! paraxial mesoderm relationship: part_of GO:0048339 ! paraxial mesoderm development relationship: results_in_morphogenesis_of UBERON:0003077 ! paraxial mesoderm [Term] id: GO:0048341 name: paraxial mesoderm formation namespace: biological_process def: "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003077 ! paraxial mesoderm relationship: part_of GO:0048340 ! paraxial mesoderm morphogenesis relationship: results_in_formation_of UBERON:0003077 ! paraxial mesoderm [Term] id: GO:0048368 name: lateral mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." [GOC:go_curators] synonym: "lateral plate mesoderm development" EXACT [] is_a: GO:0007498 ! mesoderm development is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003081 ! lateral plate mesoderm relationship: results_in_development_of UBERON:0003081 ! lateral plate mesoderm [Term] id: GO:0048369 name: lateral mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the lateral mesoderm are generated and organized." [GOC:go_curators] synonym: "lateral plate mesoderm morphogenesis" EXACT [] is_a: GO:0048332 ! mesoderm morphogenesis is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm relationship: part_of GO:0048368 ! lateral mesoderm development relationship: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm [Term] id: GO:0048370 name: lateral mesoderm formation namespace: biological_process def: "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:jid] synonym: "lateral plate mesoderm biosynthesis" EXACT [] synonym: "lateral plate mesoderm formation" EXACT [] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm relationship: part_of GO:0048369 ! lateral mesoderm morphogenesis relationship: results_in_morphogenesis_of UBERON:0003081 ! lateral plate mesoderm [Term] id: GO:0048389 name: intermediate mesoderm development namespace: biological_process def: "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:dgh] is_a: GO:0007498 ! mesoderm development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003064 ! intermediate mesoderm relationship: results_in_development_of UBERON:0003064 ! intermediate mesoderm [Term] id: GO:0048390 name: intermediate mesoderm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." [GOC:go_curators] is_a: GO:0048332 ! mesoderm morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003064 ! intermediate mesoderm relationship: part_of GO:0048389 ! intermediate mesoderm development relationship: results_in_morphogenesis_of UBERON:0003064 ! intermediate mesoderm [Term] id: GO:0048391 name: intermediate mesoderm formation namespace: biological_process def: "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." [GOC:dgh] is_a: GO:0001707 ! mesoderm formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003064 ! intermediate mesoderm relationship: part_of GO:0048390 ! intermediate mesoderm morphogenesis relationship: results_in_formation_of UBERON:0003064 ! intermediate mesoderm [Term] id: GO:0048468 name: cell development namespace: biological_process def: "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." [GOC:go_curators] subset: goslim_candida synonym: "terminal differentiation" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0008150 ! biological_process intersection_of: results_in_development_of CL:0000000 ! cell relationship: part_of GO:0030154 ! cell differentiation relationship: results_in_development_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048469 name: cell maturation namespace: biological_process def: "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." [GOC:go_curators] subset: goslim_pir synonym: "functional differentiation" RELATED [GOC:dph] is_a: GO:0021700 ! developmental maturation is_a: GO:0048869 ! cellular developmental process intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000000 ! cell relationship: part_of GO:0048468 ! cell development relationship: results_in_maturation_of CL:0000000 ! cell property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24390" xsd:anyURI [Term] id: GO:0048477 name: oogenesis namespace: biological_process alt_id: GO:0009993 alt_id: GO:0048157 def: "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." [GOC:kmv, GOC:mtg_sensu, GOC:pr] synonym: "ovum development" EXACT systematic_synonym [] xref: Wikipedia:Oogenesis is_a: GO:0007281 ! germ cell development is_a: GO:0007292 ! female gamete generation intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0000025 ! egg cell relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: results_in_development_of CL:0000025 ! egg cell [Term] id: GO:0048483 name: autonomic nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." [FMA:9905, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002410 ! autonomic nervous system relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0002410 ! autonomic nervous system [Term] id: GO:0048485 name: sympathetic nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." [FMA:9906, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000013 ! sympathetic nervous system relationship: part_of GO:0048483 ! autonomic nervous system development relationship: results_in_development_of UBERON:0000013 ! sympathetic nervous system [Term] id: GO:0048486 name: parasympathetic nervous system development namespace: biological_process def: "The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia." [FMA:9907, GOC:jid, GOC:sr] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000011 ! parasympathetic nervous system relationship: part_of GO:0048483 ! autonomic nervous system development relationship: results_in_development_of UBERON:0000011 ! parasympathetic nervous system [Term] id: GO:0048505 name: regulation of timing of cell differentiation namespace: biological_process def: "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." [GOC:bf, GOC:dph, GOC:jid, GOC:tb] synonym: "timing of cell differentiation" RELATED [] is_a: GO:0040034 ! regulation of development, heterochronic is_a: GO:0045595 ! regulation of cell differentiation [Term] id: GO:0048511 name: rhythmic process namespace: biological_process def: "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." [GOC:jid] subset: goslim_pir synonym: "rhythm" RELATED [] is_a: GO:0008150 ! biological_process relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms [Term] id: GO:0048513 name: animal organ development namespace: biological_process def: "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:dph, GOC:jid] synonym: "development of an organ" EXACT [] synonym: "organogenesis" EXACT [] xref: Wikipedia:Organogenesis is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000062 ! organ relationship: results_in_development_of UBERON:0000062 ! organ [Term] id: GO:0048514 name: blood vessel morphogenesis namespace: biological_process def: "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:jid] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001981 ! blood vessel relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_morphogenesis_of UBERON:0001981 ! blood vessel [Term] id: GO:0048515 name: spermatid differentiation namespace: biological_process def: "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:jid] synonym: "spermatid cell differentiation" EXACT [] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000018 ! spermatid relationship: part_of GO:0007283 ! spermatogenesis relationship: results_in_acquisition_of_features_of CL:0000018 ! spermatid [Term] id: GO:0048518 name: positive regulation of biological process namespace: biological_process alt_id: GO:0043119 def: "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] subset: gocheck_do_not_annotate synonym: "activation of biological process" NARROW [] synonym: "positive regulation of physiological process" EXACT [] synonym: "stimulation of biological process" NARROW [] synonym: "up regulation of biological process" EXACT [] synonym: "up-regulation of biological process" EXACT [] synonym: "upregulation of biological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008150 ! biological_process relationship: positively_regulates GO:0008150 ! biological_process [Term] id: GO:0048519 name: negative regulation of biological process namespace: biological_process alt_id: GO:0043118 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:jid] subset: gocheck_do_not_annotate synonym: "down regulation of biological process" EXACT [] synonym: "down-regulation of biological process" EXACT [] synonym: "downregulation of biological process" EXACT [] synonym: "inhibition of biological process" NARROW [] synonym: "negative regulation of physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008150 ! biological_process relationship: negatively_regulates GO:0008150 ! biological_process [Term] id: GO:0048520 name: positive regulation of behavior namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "activation of behavior" NARROW [] synonym: "stimulation of behavior" NARROW [] synonym: "up regulation of behavior" EXACT [] synonym: "up-regulation of behavior" EXACT [] synonym: "upregulation of behavior" EXACT [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007610 ! behavior relationship: positively_regulates GO:0007610 ! behavior [Term] id: GO:0048521 name: negative regulation of behavior namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:jid, GOC:pr] synonym: "down regulation of behavior" EXACT [] synonym: "down-regulation of behavior" EXACT [] synonym: "downregulation of behavior" EXACT [] synonym: "inhibition of behavior" NARROW [] is_a: GO:0050795 ! regulation of behavior is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007610 ! behavior relationship: negatively_regulates GO:0007610 ! behavior [Term] id: GO:0048522 name: positive regulation of cellular process namespace: biological_process alt_id: GO:0051242 def: "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] subset: gocheck_do_not_annotate synonym: "activation of cellular process" NARROW [] synonym: "positive regulation of cellular physiological process" EXACT [] synonym: "stimulation of cellular process" NARROW [] synonym: "up regulation of cellular process" EXACT [] synonym: "up-regulation of cellular process" EXACT [] synonym: "upregulation of cellular process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009987 ! cellular process relationship: positively_regulates GO:0009987 ! cellular process [Term] id: GO:0048523 name: negative regulation of cellular process namespace: biological_process alt_id: GO:0051243 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:jid] subset: gocheck_do_not_annotate synonym: "down regulation of cellular process" EXACT [] synonym: "down-regulation of cellular process" EXACT [] synonym: "downregulation of cellular process" EXACT [] synonym: "inhibition of cellular process" NARROW [] synonym: "negative regulation of cellular physiological process" EXACT [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009987 ! cellular process relationship: negatively_regulates GO:0009987 ! cellular process [Term] id: GO:0048534 name: hematopoietic or lymphoid organ development namespace: biological_process def: "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." [GOC:add, GOC:rl, ISBN:0781735149] synonym: "haematopoietic or lymphoid organ development" EXACT [] synonym: "haemopoietic or lymphoid organ development" EXACT [] synonym: "hemopoietic or lymphoid organ development" EXACT [] is_a: GO:0048513 ! animal organ development relationship: part_of GO:0002520 ! immune system development [Term] id: GO:0048536 name: spleen development namespace: biological_process def: "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions." [GOC:add, ISBN:0781735149] is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002106 ! spleen relationship: results_in_development_of UBERON:0002106 ! spleen [Term] id: GO:0048539 name: bone marrow development namespace: biological_process def: "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." [GOC:add, ISBN:0781735149] is_a: GO:0009888 ! tissue development is_a: GO:0048534 ! hematopoietic or lymphoid organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002371 ! bone marrow relationship: part_of GO:0060348 ! bone development relationship: results_in_development_of UBERON:0002371 ! bone marrow [Term] id: GO:0048545 name: response to steroid hormone namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." [GOC:go_curators] synonym: "response to steroid hormone stimulus" EXACT [GOC:dos] is_a: GO:0009725 ! response to hormone is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0033993 ! response to lipid intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:26764 ! steroid hormone relationship: has_input CHEBI:26764 ! steroid hormone [Term] id: GO:0048546 name: digestive tract morphogenesis namespace: biological_process alt_id: GO:0048547 def: "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:dph, GOC:go_curators, PMID:12618131] synonym: "alimentary canal morphogenesis" EXACT [] synonym: "digestive tube morphogenesis" EXACT [] synonym: "gastrointestinal tract morphogenesis" EXACT [] synonym: "gut morphogenesis" BROAD [GOC:dph] synonym: "intestinal morphogenesis" NARROW [] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001555 ! digestive tract relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_morphogenesis_of UBERON:0001555 ! digestive tract [Term] id: GO:0048562 name: embryonic organ morphogenesis namespace: biological_process def: "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048598 ! embryonic morphogenesis relationship: part_of GO:0048568 ! embryonic organ development [Term] id: GO:0048565 name: digestive tract development namespace: biological_process def: "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." [GOC:go_curators] synonym: "gut development" BROAD [GOC:dph] synonym: "intestinal development" NARROW [] synonym: "intestine development" NARROW [] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001555 ! digestive tract relationship: part_of GO:0055123 ! digestive system development relationship: results_in_development_of UBERON:0001555 ! digestive tract [Term] id: GO:0048568 name: embryonic organ development namespace: biological_process def: "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:jid] synonym: "embryonic organogenesis" EXACT [] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: part_of GO:0009790 ! embryo development intersection_of: results_in_development_of UBERON:0000062 ! organ relationship: part_of GO:0009790 ! embryo development [Term] id: GO:0048570 name: notochord morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." [GOC:jid] is_a: GO:0048562 ! embryonic organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002328 ! notochord relationship: part_of GO:0030903 ! notochord development relationship: results_in_morphogenesis_of UBERON:0002328 ! notochord [Term] id: GO:0048580 name: regulation of post-embryonic development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009791 ! post-embryonic development relationship: regulates GO:0009791 ! post-embryonic development [Term] id: GO:0048581 name: negative regulation of post-embryonic development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "down regulation of post-embryonic development" EXACT [] synonym: "down-regulation of post-embryonic development" EXACT [] synonym: "downregulation of post-embryonic development" EXACT [] synonym: "inhibition of post-embryonic development" NARROW [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009791 ! post-embryonic development relationship: negatively_regulates GO:0009791 ! post-embryonic development [Term] id: GO:0048582 name: positive regulation of post-embryonic development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." [GOC:jid] synonym: "activation of post-embryonic development" NARROW [] synonym: "stimulation of post-embryonic development" NARROW [] synonym: "up regulation of post-embryonic development" EXACT [] synonym: "up-regulation of post-embryonic development" EXACT [] synonym: "upregulation of post-embryonic development" EXACT [] is_a: GO:0048580 ! regulation of post-embryonic development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009791 ! post-embryonic development relationship: positively_regulates GO:0009791 ! post-embryonic development [Term] id: GO:0048583 name: regulation of response to stimulus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050896 ! response to stimulus relationship: regulates GO:0050896 ! response to stimulus [Term] id: GO:0048584 name: positive regulation of response to stimulus namespace: biological_process def: "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "activation of response to stimulus" NARROW [] synonym: "stimulation of response to stimulus" NARROW [] synonym: "up regulation of response to stimulus" EXACT [] synonym: "up-regulation of response to stimulus" EXACT [] synonym: "upregulation of response to stimulus" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050896 ! response to stimulus relationship: positively_regulates GO:0050896 ! response to stimulus [Term] id: GO:0048585 name: negative regulation of response to stimulus namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." [GOC:jid] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate synonym: "down regulation of response to stimulus" EXACT [] synonym: "down-regulation of response to stimulus" EXACT [] synonym: "downregulation of response to stimulus" EXACT [] synonym: "inhibition of response to stimulus" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050896 ! response to stimulus relationship: negatively_regulates GO:0050896 ! response to stimulus [Term] id: GO:0048588 name: developmental cell growth namespace: biological_process def: "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." [GOC:go_curators, GOC:isa_complete] synonym: "developmental growth of a unicellular organism" EXACT [] is_a: GO:0016049 ! cell growth is_a: GO:0048589 ! developmental growth relationship: part_of GO:0048468 ! cell development [Term] id: GO:0048589 name: developmental growth namespace: biological_process def: "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:go_curators] is_a: GO:0040007 ! growth intersection_of: GO:0040007 ! growth intersection_of: part_of GO:0032502 ! developmental process relationship: part_of GO:0032502 ! developmental process [Term] id: GO:0048592 name: eye morphogenesis namespace: biological_process alt_id: GO:0048748 def: "The process in which the anatomical structures of the eye are generated and organized." [GOC:jid, GOC:mtg_sensu] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000970 ! eye relationship: part_of GO:0001654 ! eye development relationship: results_in_morphogenesis_of UBERON:0000970 ! eye [Term] id: GO:0048593 name: camera-type eye morphogenesis namespace: biological_process alt_id: GO:0048594 alt_id: GO:0048595 def: "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." [GOC:jid, GOC:mtg_sensu] synonym: "camera-style eye morphogenesis" EXACT [GOC:dph] is_a: GO:0048592 ! eye morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000019 ! camera-type eye relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_morphogenesis_of UBERON:0000019 ! camera-type eye [Term] id: GO:0048596 name: embryonic camera-type eye morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the eye are generated and organized during embryonic development." [GOC:jid, GOC:mtg_sensu] synonym: "embryonic eye morphogenesis" BROAD [] is_a: GO:0048048 ! embryonic eye morphogenesis relationship: part_of GO:0031076 ! embryonic camera-type eye development relationship: part_of GO:0048593 ! camera-type eye morphogenesis [Term] id: GO:0048598 name: embryonic morphogenesis namespace: biological_process alt_id: GO:0048828 def: "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." [GOC:jid, GOC:mtg_sensu] synonym: "embryonic anatomical structure morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009790 ! embryo development [Term] id: GO:0048599 name: oocyte development namespace: biological_process def: "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:go_curators] is_a: GO:0007281 ! germ cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000023 ! oocyte relationship: part_of GO:0009994 ! oocyte differentiation relationship: results_in_development_of CL:0000023 ! oocyte [Term] id: GO:0048601 name: oocyte morphogenesis namespace: biological_process def: "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." [GOC:go_curators] synonym: "oocyte morphogenesis during differentiation" EXACT [] is_a: GO:0000904 ! cell morphogenesis involved in differentiation is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of CL:0000023 ! oocyte relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0048599 ! oocyte development relationship: results_in_morphogenesis_of CL:0000023 ! oocyte [Term] id: GO:0048608 name: reproductive structure development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." [GOC:dph, GOC:isa_complete, GOC:jid] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0048856 ! anatomical structure development relationship: part_of GO:0061458 ! reproductive system development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23445" xsd:anyURI [Term] id: GO:0048609 name: multicellular organismal reproductive process namespace: biological_process def: "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." [GOC:dph, GOC:jid, GOC:tb] synonym: "organismal reproductive process" BROAD [] synonym: "reproductive process in a multicellular organism" EXACT [] is_a: GO:0022414 ! reproductive process relationship: part_of GO:0032504 ! multicellular organism reproduction [Term] id: GO:0048627 name: myoblast development namespace: biological_process def: "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000056 ! myoblast relationship: part_of GO:0045445 ! myoblast differentiation relationship: results_in_development_of CL:0000056 ! myoblast [Term] id: GO:0048628 name: myoblast maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:dph, GOC:mtg_muscle] is_a: GO:0048469 ! cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000056 ! myoblast relationship: part_of GO:0048627 ! myoblast development relationship: results_in_maturation_of CL:0000056 ! myoblast [Term] id: GO:0048630 name: skeletal muscle tissue growth namespace: biological_process def: "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0001134 ! skeletal muscle tissue relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: results_in_growth_of UBERON:0001134 ! skeletal muscle tissue [Term] id: GO:0048631 name: regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048630 ! skeletal muscle tissue growth relationship: regulates GO:0048630 ! skeletal muscle tissue growth [Term] id: GO:0048632 name: negative regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "down regulation of skeletal muscle growth" EXACT [] synonym: "down-regulation of skeletal muscle growth" EXACT [] synonym: "downregulation of skeletal muscle growth" EXACT [] synonym: "inhibition of skeletal muscle growth" NARROW [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048640 ! negative regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048630 ! skeletal muscle tissue growth relationship: negatively_regulates GO:0048630 ! skeletal muscle tissue growth [Term] id: GO:0048633 name: positive regulation of skeletal muscle tissue growth namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle growth." [GOC:lm, PMID:15726494, PMID:15907921] synonym: "activation of skeletal muscle growth" NARROW [] synonym: "stimulation of skeletal muscle growth" NARROW [] synonym: "up regulation of skeletal muscle growth" EXACT [] synonym: "up-regulation of skeletal muscle growth" EXACT [] synonym: "upregulation of skeletal muscle growth" EXACT [] is_a: GO:0048631 ! regulation of skeletal muscle tissue growth is_a: GO:0048639 ! positive regulation of developmental growth is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048630 ! skeletal muscle tissue growth relationship: positively_regulates GO:0048630 ! skeletal muscle tissue growth [Term] id: GO:0048634 name: regulation of muscle organ development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle development." [GOC:go_curators] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007517 ! muscle organ development relationship: regulates GO:0007517 ! muscle organ development [Term] id: GO:0048635 name: negative regulation of muscle organ development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." [GOC:go_curators] synonym: "down regulation of muscle development" EXACT [] synonym: "down-regulation of muscle development" EXACT [] synonym: "downregulation of muscle development" EXACT [] synonym: "inhibition of muscle development" NARROW [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007517 ! muscle organ development relationship: negatively_regulates GO:0007517 ! muscle organ development [Term] id: GO:0048636 name: positive regulation of muscle organ development namespace: biological_process def: "Any process that activates, maintains or increases the rate of muscle development." [GOC:go_curators] synonym: "activation of muscle development" NARROW [] synonym: "stimulation of muscle development" NARROW [] synonym: "up regulation of muscle development" EXACT [] synonym: "up-regulation of muscle development" EXACT [] synonym: "upregulation of muscle development" EXACT [] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007517 ! muscle organ development relationship: positively_regulates GO:0007517 ! muscle organ development [Term] id: GO:0048638 name: regulation of developmental growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of developmental growth." [GOC:go_curators] is_a: GO:0040008 ! regulation of growth is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048589 ! developmental growth relationship: regulates GO:0048589 ! developmental growth [Term] id: GO:0048639 name: positive regulation of developmental growth namespace: biological_process def: "Any process that activates, maintains or increases the rate of developmental growth." [GOC:go_curators] synonym: "activation of developmental growth" NARROW [] synonym: "stimulation of developmental growth" NARROW [] synonym: "up regulation of developmental growth" EXACT [] synonym: "up-regulation of developmental growth" EXACT [] synonym: "upregulation of developmental growth" EXACT [] is_a: GO:0045927 ! positive regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051094 ! positive regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048589 ! developmental growth relationship: positively_regulates GO:0048589 ! developmental growth [Term] id: GO:0048640 name: negative regulation of developmental growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." [GOC:go_curators] synonym: "down regulation of developmental growth" EXACT [] synonym: "down-regulation of developmental growth" EXACT [] synonym: "downregulation of developmental growth" EXACT [] synonym: "inhibition of developmental growth" NARROW [] is_a: GO:0045926 ! negative regulation of growth is_a: GO:0048638 ! regulation of developmental growth is_a: GO:0051093 ! negative regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048589 ! developmental growth relationship: negatively_regulates GO:0048589 ! developmental growth [Term] id: GO:0048641 name: regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007519 ! skeletal muscle tissue development relationship: regulates GO:0007519 ! skeletal muscle tissue development [Term] id: GO:0048642 name: negative regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." [GOC:go_curators] synonym: "down regulation of skeletal muscle development" EXACT [] synonym: "down-regulation of skeletal muscle development" EXACT [] synonym: "downregulation of skeletal muscle development" EXACT [] synonym: "inhibition of skeletal muscle development" NARROW [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007519 ! skeletal muscle tissue development relationship: negatively_regulates GO:0007519 ! skeletal muscle tissue development [Term] id: GO:0048643 name: positive regulation of skeletal muscle tissue development namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." [GOC:go_curators] synonym: "activation of skeletal muscle development" NARROW [] synonym: "stimulation of skeletal muscle development" NARROW [] synonym: "up regulation of skeletal muscle development" EXACT [] synonym: "up-regulation of skeletal muscle development" EXACT [] synonym: "upregulation of skeletal muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0048641 ! regulation of skeletal muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007519 ! skeletal muscle tissue development relationship: positively_regulates GO:0007519 ! skeletal muscle tissue development [Term] id: GO:0048644 name: muscle organ morphogenesis namespace: biological_process def: "The process in which the anatomical structures of muscle are generated and organized." [GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001630 ! muscle organ relationship: part_of GO:0007517 ! muscle organ development relationship: results_in_morphogenesis_of UBERON:0001630 ! muscle organ [Term] id: GO:0048645 name: animal organ formation namespace: biological_process def: "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." [GOC:dph, GOC:jid] synonym: "animal organ primordium initiation" NARROW [] synonym: "initiation of an animal organ primordium" NARROW [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003103 ! compound organ relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: results_in_formation_of UBERON:0003103 ! compound organ [Term] id: GO:0048646 name: anatomical structure formation involved in morphogenesis namespace: biological_process def: "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GOC:dph, GOC:jid, GOC:tb] comment: Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense. subset: goslim_chembl synonym: "formation of an anatomical structure involved in morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0032502 ! developmental process relationship: part_of GO:0009653 ! anatomical structure morphogenesis [Term] id: GO:0048659 name: smooth muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." [CL:0000192, GOC:ebc, PMID:1840698] synonym: "SMC proliferation" EXACT [] is_a: GO:0033002 ! muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000192 ! smooth muscle cell relationship: acts_on_population_of CL:0000192 ! smooth muscle cell [Term] id: GO:0048660 name: regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "regulation of SMC proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048659 ! smooth muscle cell proliferation relationship: regulates GO:0048659 ! smooth muscle cell proliferation [Term] id: GO:0048661 name: positive regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "activation of smooth muscle cell proliferation" NARROW [] synonym: "positive regulation of SMC proliferation" EXACT [] synonym: "stimulation of smooth muscle cell proliferation" NARROW [] synonym: "up regulation of smooth muscle cell proliferation" EXACT [] synonym: "up-regulation of smooth muscle cell proliferation" EXACT [] synonym: "upregulation of smooth muscle cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048659 ! smooth muscle cell proliferation relationship: positively_regulates GO:0048659 ! smooth muscle cell proliferation [Term] id: GO:0048662 name: negative regulation of smooth muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." [CL:0000192, GOC:ebc] synonym: "down regulation of smooth muscle cell proliferation" EXACT [] synonym: "down-regulation of smooth muscle cell proliferation" EXACT [] synonym: "downregulation of smooth muscle cell proliferation" EXACT [] synonym: "inhibition of smooth muscle cell proliferation" NARROW [] synonym: "negative regulation of SMC proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048659 ! smooth muscle cell proliferation relationship: negatively_regulates GO:0048659 ! smooth muscle cell proliferation [Term] id: GO:0048666 name: neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000540 ! neuron relationship: part_of GO:0030182 ! neuron differentiation relationship: results_in_development_of CL:0000540 ! neuron [Term] id: GO:0048667 name: cell morphogenesis involved in neuron differentiation namespace: biological_process def: "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." [GOC:dph, GOC:tb] synonym: "neuron morphogenesis involved in differentiation" EXACT [GOC:dph, GOC:tb] is_a: GO:0000904 ! cell morphogenesis involved in differentiation intersection_of: GO:0000902 ! cell morphogenesis intersection_of: part_of GO:0030182 ! neuron differentiation relationship: part_of GO:0048666 ! neuron development [Term] id: GO:0048699 name: generation of neurons namespace: biological_process def: "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." [GOC:nln] synonym: "neuron generation" EXACT [] is_a: GO:0022008 ! neurogenesis [Term] id: GO:0048705 name: skeletal system morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the skeleton are generated and organized." [GOC:dph, GOC:dsf, GOC:jid, GOC:tb] synonym: "skeletal morphogenesis" EXACT [GOC:dph, GOC:tb] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001434 ! skeletal system relationship: part_of GO:0001501 ! skeletal system development relationship: results_in_morphogenesis_of UBERON:0001434 ! skeletal system [Term] id: GO:0048709 name: oligodendrocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system." [GOC:vp, PMID:15139015] is_a: GO:0010001 ! glial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000128 ! oligodendrocyte relationship: part_of GO:0007417 ! central nervous system development relationship: results_in_acquisition_of_features_of CL:0000128 ! oligodendrocyte [Term] id: GO:0048713 name: regulation of oligodendrocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] is_a: GO:0045685 ! regulation of glial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048709 ! oligodendrocyte differentiation relationship: regulates GO:0048709 ! oligodendrocyte differentiation [Term] id: GO:0048714 name: positive regulation of oligodendrocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "activation of oligodendrocyte differentiation" NARROW [] synonym: "stimulation of oligodendrocyte differentiation" NARROW [] synonym: "up regulation of oligodendrocyte differentiation" EXACT [] synonym: "up-regulation of oligodendrocyte differentiation" EXACT [] synonym: "upregulation of oligodendrocyte differentiation" EXACT [] is_a: GO:0045687 ! positive regulation of glial cell differentiation is_a: GO:0048713 ! regulation of oligodendrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048709 ! oligodendrocyte differentiation relationship: positively_regulates GO:0048709 ! oligodendrocyte differentiation [Term] id: GO:0048715 name: negative regulation of oligodendrocyte differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation." [GOC:vp, PMID:15139015] synonym: "down regulation of oligodendrocyte differentiation" EXACT [] synonym: "down-regulation of oligodendrocyte differentiation" EXACT [] synonym: "downregulation of oligodendrocyte differentiation" EXACT [] synonym: "inhibition of oligodendrocyte differentiation" NARROW [] is_a: GO:0045686 ! negative regulation of glial cell differentiation is_a: GO:0048713 ! regulation of oligodendrocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048709 ! oligodendrocyte differentiation relationship: negatively_regulates GO:0048709 ! oligodendrocyte differentiation [Term] id: GO:0048729 name: tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tissue are generated and organized." [GOC:dph, GOC:jid] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000479 ! tissue relationship: part_of GO:0009888 ! tissue development relationship: results_in_morphogenesis_of UBERON:0000479 ! tissue [Term] id: GO:0048730 name: epidermis morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." [GOC:jid, UBERON:0001003] synonym: "hypodermis morphogenesis" RELATED [GOC:kmv, GOC:rk] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007376 ! outer epithelium relationship: part_of GO:0008544 ! epidermis development relationship: results_in_morphogenesis_of UBERON:0007376 ! outer epithelium [Term] id: GO:0048731 name: system development namespace: biological_process def: "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." [GOC:dph, GOC:jid] subset: goslim_mouse is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000467 ! anatomical system relationship: part_of GO:0007275 ! multicellular organism development relationship: results_in_development_of UBERON:0000467 ! anatomical system [Term] id: GO:0048732 name: gland development namespace: biological_process def: "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." [GOC:jid] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002530 ! gland relationship: results_in_development_of UBERON:0002530 ! gland [Term] id: GO:0048736 name: appendage development namespace: biological_process def: "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." [GOC:jid, GOC:rc] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000026 ! appendage relationship: part_of GO:0007275 ! multicellular organism development relationship: results_in_development_of UBERON:0000026 ! appendage [Term] id: GO:0048738 name: cardiac muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] synonym: "heart muscle development" EXACT [] is_a: GO:0014706 ! striated muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0048741 name: skeletal muscle fiber development namespace: biological_process def: "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:ef, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "skeletal muscle fibre development" EXACT [] synonym: "skeletal myofiber development" EXACT [] synonym: "skeletal myofibre development" EXACT [] is_a: GO:0014904 ! myotube cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0008002 ! skeletal muscle fiber relationship: part_of GO:0007519 ! skeletal muscle tissue development relationship: results_in_development_of CL:0008002 ! skeletal muscle fiber [Term] id: GO:0048742 name: regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:mtg_muscle, GOC:sm] synonym: "regulation of skeletal muscle fibre development" EXACT [] synonym: "regulation of skeletal myofiber development" EXACT [] synonym: "regulation of skeletal myofibre development" EXACT [] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048741 ! skeletal muscle fiber development relationship: regulates GO:0048741 ! skeletal muscle fiber development [Term] id: GO:0048743 name: positive regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "activation of skeletal muscle fiber development" NARROW [] synonym: "positive regulation of skeletal muscle fibre development" EXACT [] synonym: "positive regulation of skeletal myofiber development" EXACT [] synonym: "positive regulation of skeletal myofibre development" EXACT [] synonym: "stimulation of skeletal muscle fiber development" NARROW [] synonym: "up regulation of skeletal muscle fiber development" EXACT [] synonym: "up-regulation of skeletal muscle fiber development" EXACT [] synonym: "upregulation of skeletal muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0048643 ! positive regulation of skeletal muscle tissue development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048741 ! skeletal muscle fiber development relationship: positively_regulates GO:0048741 ! skeletal muscle fiber development [Term] id: GO:0048744 name: negative regulation of skeletal muscle fiber development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." [GOC:dph, GOC:jid, GOC:lm, GOC:mtg_muscle] synonym: "down regulation of skeletal muscle fiber development" EXACT [] synonym: "down-regulation of skeletal muscle fiber development" EXACT [] synonym: "downregulation of skeletal muscle fiber development" EXACT [] synonym: "inhibition of skeletal muscle fiber development" NARROW [] synonym: "negative regulation of skeletal muscle fibre development" EXACT [] synonym: "negative regulation of skeletal myofiber development" EXACT [] synonym: "negative regulation of skeletal myofibre development" EXACT [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0048742 ! regulation of skeletal muscle fiber development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048741 ! skeletal muscle fiber development relationship: negatively_regulates GO:0048741 ! skeletal muscle fiber development [Term] id: GO:0048745 name: smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." [GOC:dph, GOC:jid, GOC:lm] is_a: GO:0060537 ! muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001135 ! smooth muscle tissue relationship: results_in_development_of UBERON:0001135 ! smooth muscle tissue [Term] id: GO:0048749 name: compound eye development namespace: biological_process alt_id: GO:0007456 def: "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." [GOC:jid, GOC:mtg_sensu, Wikipedia:Eye] synonym: "insect-type retina development" EXACT [PMID:11735386] is_a: GO:0001654 ! eye development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000018 ! compound eye relationship: results_in_development_of UBERON:0000018 ! compound eye [Term] id: GO:0048753 name: pigment granule organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." [GOC:rc] subset: goslim_pir synonym: "pigment granule organisation" EXACT [] synonym: "pigment granule organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016050 ! vesicle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0048770 ! pigment granule relationship: part_of GO:0033059 ! cellular pigmentation relationship: results_in_organization_of GO:0048770 ! pigment granule [Term] id: GO:0048754 name: branching morphogenesis of an epithelial tube namespace: biological_process def: "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." [GOC:dgh, GOC:dph, GOC:jid] synonym: "tubulogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0035239 ! tube morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: results_in_morphogenesis_of UBERON:0000025 ! tube relationship: part_of GO:0060562 ! epithelial tube morphogenesis [Term] id: GO:0048755 name: branching morphogenesis of a nerve namespace: biological_process def: "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." [GOC:dgh, GOC:dph, GOC:jid] is_a: GO:0001763 ! morphogenesis of a branching structure intersection_of: GO:0001763 ! morphogenesis of a branching structure intersection_of: results_in_morphogenesis_of UBERON:0001021 ! nerve relationship: part_of GO:0007399 ! nervous system development relationship: results_in_morphogenesis_of UBERON:0001021 ! nerve [Term] id: GO:0048762 name: mesenchymal cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph, GOC:jid] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell relationship: part_of GO:0060485 ! mesenchyme development relationship: results_in_acquisition_of_features_of CL:0008019 ! mesenchymal cell [Term] id: GO:0048770 name: pigment granule namespace: cellular_component def: "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." [GOC:jid, GOC:mh] is_a: GO:0031410 ! cytoplasmic vesicle [Term] id: GO:0048793 name: pronephros development namespace: biological_process def: "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:bf, GOC:mtg_kidney_jan10, PMID:10535314, PMID:15968585, PMID:18322540, XAO:00002000, ZFA:0000151] synonym: "pronephric kidney development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0001822 ! kidney development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002120 ! pronephros relationship: results_in_development_of UBERON:0002120 ! pronephros [Term] id: GO:0048799 name: animal organ maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." [GOC:curators] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0000062 ! organ relationship: part_of GO:0048513 ! animal organ development relationship: results_in_maturation_of UBERON:0000062 ! organ [Term] id: GO:0048806 name: genitalia development namespace: biological_process def: "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." [GOC:jid] synonym: "genital development" EXACT [] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development relationship: part_of GO:0007548 ! sex differentiation [Term] id: GO:0048808 name: male genitalia morphogenesis namespace: biological_process def: "The process in which the anatomical structures of male genitalia are generated and organized." [GOC:ems, ISBN:0140512888] synonym: "male genital morphogenesis" RELATED [] is_a: GO:0035112 ! genitalia morphogenesis is_a: GO:0090598 ! male anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000079 ! male reproductive system relationship: part_of GO:0030539 ! male genitalia development relationship: results_in_morphogenesis_of UBERON:0000079 ! male reproductive system [Term] id: GO:0048812 name: neuron projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." [GOC:mah] synonym: "neurite biosynthesis" NARROW [] synonym: "neurite formation" NARROW [] synonym: "neurite growth" NARROW [] synonym: "neurite morphogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0120039 ! plasma membrane bounded cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0043005 ! neuron projection relationship: part_of GO:0031175 ! neuron projection development relationship: results_in_morphogenesis_of GO:0043005 ! neuron projection [Term] id: GO:0048821 name: erythrocyte development namespace: biological_process def: "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." [GOC:devbiol] synonym: "RBC development" EXACT [CL:0000232] synonym: "red blood cell development" EXACT [CL:0000232] is_a: GO:0061515 ! myeloid cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000232 ! erythrocyte relationship: part_of GO:0030218 ! erythrocyte differentiation relationship: results_in_development_of CL:0000232 ! erythrocyte [Term] id: GO:0048822 name: enucleate erythrocyte development namespace: biological_process def: "The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] synonym: "enucleate RBC development" EXACT [CL:0000232] synonym: "enucleate red blood cell development" EXACT [CL:0000232] is_a: GO:0048821 ! erythrocyte development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000595 ! enucleate erythrocyte relationship: part_of GO:0043353 ! enucleate erythrocyte differentiation relationship: results_in_development_of CL:0000595 ! enucleate erythrocyte [Term] id: GO:0048823 name: nucleate erythrocyte development namespace: biological_process def: "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:devbiol] synonym: "nucleate RBC development" EXACT [CL:0000232] synonym: "nucleate red blood cell development" EXACT [CL:0000232] is_a: GO:0048821 ! erythrocyte development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000562 ! nucleate erythrocyte relationship: part_of GO:0043363 ! nucleate erythrocyte differentiation relationship: results_in_development_of CL:0000562 ! nucleate erythrocyte [Term] id: GO:0048839 name: inner ear development namespace: biological_process def: "The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure." [GOC:sr] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001846 ! internal ear relationship: part_of GO:0043583 ! ear development relationship: results_in_development_of UBERON:0001846 ! internal ear [Term] id: GO:0048844 name: artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." [GOC:dsf, PMID:16740480] synonym: "arterial morphogenesis" EXACT [] synonym: "arteriogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001637 ! artery relationship: part_of GO:0060840 ! artery development relationship: results_in_morphogenesis_of UBERON:0001637 ! artery [Term] id: GO:0048845 name: venous blood vessel morphogenesis namespace: biological_process def: "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." [GOC:dsf, PMID:16740480] synonym: "vein morphogenesis" BROAD [] synonym: "venous morphogenesis" EXACT [] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001638 ! vein relationship: part_of GO:0060841 ! venous blood vessel development relationship: results_in_morphogenesis_of UBERON:0001638 ! vein [Term] id: GO:0048853 name: forebrain morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)." [GOC:cvs, GOC:dgh, GOC:dph, GOC:jid] synonym: "prosencephalon morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001890 ! forebrain relationship: part_of GO:0030900 ! forebrain development relationship: part_of GO:0048854 ! brain morphogenesis relationship: results_in_morphogenesis_of UBERON:0001890 ! forebrain [Term] id: GO:0048854 name: brain morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." [GOC:dgh, GOC:jid] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000955 ! brain relationship: part_of GO:0007420 ! brain development relationship: results_in_morphogenesis_of UBERON:0000955 ! brain [Term] id: GO:0048856 name: anatomical structure development namespace: biological_process def: "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] subset: goslim_chembl subset: goslim_generic subset: goslim_plant synonym: "development of an anatomical structure" EXACT [] is_a: GO:0032502 ! developmental process intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of UBERON:0000061 ! anatomical structure relationship: results_in_development_of UBERON:0000061 ! anatomical structure [Term] id: GO:0048857 name: neural nucleus development namespace: biological_process def: "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." [GO_REF:0000021] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000125 ! neural nucleus relationship: results_in_development_of UBERON:0000125 ! neural nucleus [Term] id: GO:0048858 name: cell projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a cell projection are generated and organized." [GO_REF:0000021] is_a: GO:0030030 ! cell projection organization is_a: GO:0032990 ! cell part morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0042995 ! cell projection relationship: part_of GO:0000902 ! cell morphogenesis relationship: results_in_morphogenesis_of GO:0042995 ! cell projection [Term] id: GO:0048859 name: formation of anatomical boundary namespace: biological_process def: "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." [GO_REF:0000021] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0007651 ! anatomical junction relationship: results_in_formation_of UBERON:0007651 ! anatomical junction [Term] id: GO:0048860 name: glioblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a glioblast into daughter cells." [GOC:devbiol] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000030 ! glioblast relationship: has_input CL:0000030 ! glioblast [Term] id: GO:0048863 name: stem cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [CL:0000034, GOC:isa_complete] xref: Wikipedia:Stem_cell_differentiation is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000034 ! stem cell relationship: results_in_acquisition_of_features_of CL:0000034 ! stem cell [Term] id: GO:0048864 name: stem cell development namespace: biological_process def: "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." [CL:0000034, GOC:isa_complete] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000034 ! stem cell relationship: part_of GO:0048863 ! stem cell differentiation relationship: results_in_development_of CL:0000034 ! stem cell [Term] id: GO:0048869 name: cellular developmental process namespace: biological_process def: "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." [GOC:isa_complete] is_a: GO:0009987 ! cellular process is_a: GO:0032502 ! developmental process [Term] id: GO:0048870 name: cell motility namespace: biological_process def: "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: prokaryote_subset synonym: "cell locomotion" EXACT [] synonym: "cell movement" RELATED [] synonym: "movement of a cell" EXACT [] is_a: GO:0009987 ! cellular process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0048871 name: multicellular organismal-level homeostasis namespace: biological_process def: "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." [GOC:isa_complete] is_a: GO:0032501 ! multicellular organismal process is_a: GO:0042592 ! homeostatic process [Term] id: GO:0048872 name: homeostasis of number of cells namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." [GOC:isa_complete] synonym: "cell population homeostasis" EXACT [] synonym: "homeostasis of cell number" EXACT [GOC:dph] is_a: GO:0048871 ! multicellular organismal-level homeostasis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI [Term] id: GO:0048880 name: sensory system development namespace: biological_process def: "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." [GOC:dgh] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001032 ! sensory system relationship: results_in_development_of UBERON:0001032 ! sensory system [Term] id: GO:0048934 name: peripheral nervous system neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." [GOC:dgh] is_a: GO:0030182 ! neuron differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:2000032 ! peripheral nervous system neuron relationship: part_of GO:0007422 ! peripheral nervous system development relationship: results_in_acquisition_of_features_of CL:2000032 ! peripheral nervous system neuron [Term] id: GO:0048935 name: peripheral nervous system neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." [GOC:dgh] is_a: GO:0048666 ! neuron development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:2000032 ! peripheral nervous system neuron relationship: part_of GO:0048934 ! peripheral nervous system neuron differentiation relationship: results_in_development_of CL:2000032 ! peripheral nervous system neuron [Term] id: GO:0050000 name: chromosome localization namespace: biological_process def: "Any process in which a chromosome is transported to, or maintained in, a specific location." [GOC:ai] synonym: "chromosome localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of chromosome localization" EXACT [] synonym: "establishment and maintenance of chromosome position" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005694 ! chromosome relationship: has_primary_input GO:0005694 ! chromosome [Term] id: GO:0050432 name: catecholamine secretion namespace: biological_process def: "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, GOC:ef] is_a: GO:0032940 ! secretion by cell is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:33567 ! catecholamine [Term] id: GO:0050433 name: regulation of catecholamine secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." [GOC:ai] is_a: GO:0051952 ! regulation of amine transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050432 ! catecholamine secretion relationship: regulates GO:0050432 ! catecholamine secretion [Term] id: GO:0050657 name: nucleic acid transport namespace: biological_process def: "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai, ISBN:0198506732] is_a: GO:0015931 ! nucleobase-containing compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33696 ! nucleic acid relationship: has_primary_input CHEBI:33696 ! nucleic acid [Term] id: GO:0050658 name: RNA transport namespace: biological_process def: "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050657 ! nucleic acid transport is_a: GO:0051236 ! establishment of RNA localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: has_primary_input CHEBI:33697 ! ribonucleic acid [Term] id: GO:0050670 name: regulation of lymphocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." [GOC:ai] is_a: GO:0032944 ! regulation of mononuclear cell proliferation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046651 ! lymphocyte proliferation relationship: regulates GO:0046651 ! lymphocyte proliferation [Term] id: GO:0050671 name: positive regulation of lymphocyte proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "activation of lymphocyte proliferation" NARROW [] synonym: "stimulation of lymphocyte proliferation" NARROW [] synonym: "up regulation of lymphocyte proliferation" EXACT [] synonym: "up-regulation of lymphocyte proliferation" EXACT [] synonym: "upregulation of lymphocyte proliferation" EXACT [] is_a: GO:0032946 ! positive regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051251 ! positive regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046651 ! lymphocyte proliferation relationship: positively_regulates GO:0046651 ! lymphocyte proliferation [Term] id: GO:0050672 name: negative regulation of lymphocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." [GOC:ai] synonym: "down regulation of lymphocyte proliferation" EXACT [] synonym: "down-regulation of lymphocyte proliferation" EXACT [] synonym: "downregulation of lymphocyte proliferation" EXACT [] synonym: "inhibition of lymphocyte proliferation" NARROW [] is_a: GO:0032945 ! negative regulation of mononuclear cell proliferation is_a: GO:0050670 ! regulation of lymphocyte proliferation is_a: GO:0051250 ! negative regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046651 ! lymphocyte proliferation relationship: negatively_regulates GO:0046651 ! lymphocyte proliferation [Term] id: GO:0050673 name: epithelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." [ISBN:0721662544] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000066 ! epithelial cell relationship: acts_on_population_of CL:0000066 ! epithelial cell [Term] id: GO:0050678 name: regulation of epithelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." [GOC:ai] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050673 ! epithelial cell proliferation relationship: regulates GO:0050673 ! epithelial cell proliferation [Term] id: GO:0050679 name: positive regulation of epithelial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "activation of epithelial cell proliferation" NARROW [] synonym: "stimulation of epithelial cell proliferation" NARROW [] synonym: "up regulation of epithelial cell proliferation" EXACT [] synonym: "up-regulation of epithelial cell proliferation" EXACT [] synonym: "upregulation of epithelial cell proliferation" EXACT [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050673 ! epithelial cell proliferation relationship: positively_regulates GO:0050673 ! epithelial cell proliferation [Term] id: GO:0050680 name: negative regulation of epithelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." [GOC:ai] synonym: "down regulation of epithelial cell proliferation" EXACT [] synonym: "down-regulation of epithelial cell proliferation" EXACT [] synonym: "downregulation of epithelial cell proliferation" EXACT [] synonym: "inhibition of epithelial cell proliferation" NARROW [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050673 ! epithelial cell proliferation relationship: negatively_regulates GO:0050673 ! epithelial cell proliferation [Term] id: GO:0050708 name: regulation of protein secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] is_a: GO:0051223 ! regulation of protein transport is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009306 ! protein secretion relationship: regulates GO:0009306 ! protein secretion [Term] id: GO:0050709 name: negative regulation of protein secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "down regulation of protein secretion" EXACT [] synonym: "down-regulation of protein secretion" EXACT [] synonym: "downregulation of protein secretion" EXACT [] synonym: "inhibition of protein secretion" NARROW [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051224 ! negative regulation of protein transport is_a: GO:1903531 ! negative regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009306 ! protein secretion relationship: negatively_regulates GO:0009306 ! protein secretion [Term] id: GO:0050714 name: positive regulation of protein secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." [GOC:ai] synonym: "activation of protein secretion" NARROW [] synonym: "stimulation of protein secretion" NARROW [] synonym: "up regulation of protein secretion" EXACT [] synonym: "up-regulation of protein secretion" EXACT [] synonym: "upregulation of protein secretion" EXACT [] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0051222 ! positive regulation of protein transport is_a: GO:1903532 ! positive regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009306 ! protein secretion relationship: positively_regulates GO:0009306 ! protein secretion [Term] id: GO:0050727 name: regulation of inflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." [GOC:ai] is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006954 ! inflammatory response relationship: regulates GO:0006954 ! inflammatory response [Term] id: GO:0050728 name: negative regulation of inflammatory response namespace: biological_process alt_id: GO:0030236 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "anti-inflammatory response" EXACT [] synonym: "down regulation of inflammatory response" EXACT [] synonym: "down-regulation of inflammatory response" EXACT [] synonym: "downregulation of inflammatory response" EXACT [] synonym: "inhibition of inflammatory response" NARROW [] is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006954 ! inflammatory response relationship: negatively_regulates GO:0006954 ! inflammatory response [Term] id: GO:0050729 name: positive regulation of inflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the inflammatory response." [GOC:ai] synonym: "activation of inflammatory response" NARROW [] synonym: "stimulation of inflammatory response" NARROW [] synonym: "up regulation of inflammatory response" EXACT [] synonym: "up-regulation of inflammatory response" EXACT [] synonym: "upregulation of inflammatory response" EXACT [] is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006954 ! inflammatory response relationship: positively_regulates GO:0006954 ! inflammatory response [Term] id: GO:0050767 name: regulation of neurogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." [GOC:ai] is_a: GO:0051960 ! regulation of nervous system development is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022008 ! neurogenesis relationship: regulates GO:0022008 ! neurogenesis [Term] id: GO:0050768 name: negative regulation of neurogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "down regulation of neurogenesis" EXACT [] synonym: "down-regulation of neurogenesis" EXACT [] synonym: "downregulation of neurogenesis" EXACT [] synonym: "inhibition of neurogenesis" NARROW [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051961 ! negative regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022008 ! neurogenesis relationship: negatively_regulates GO:0022008 ! neurogenesis [Term] id: GO:0050769 name: positive regulation of neurogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." [GOC:ai] synonym: "activation of neurogenesis" NARROW [] synonym: "stimulation of neurogenesis" NARROW [] synonym: "up regulation of neurogenesis" EXACT [] synonym: "up-regulation of neurogenesis" EXACT [] synonym: "upregulation of neurogenesis" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0050767 ! regulation of neurogenesis is_a: GO:0051962 ! positive regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022008 ! neurogenesis relationship: positively_regulates GO:0022008 ! neurogenesis [Term] id: GO:0050770 name: regulation of axonogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." [GOC:ai] is_a: GO:0010975 ! regulation of neuron projection development is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007409 ! axonogenesis relationship: regulates GO:0007409 ! axonogenesis [Term] id: GO:0050771 name: negative regulation of axonogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." [GOC:ai] synonym: "down regulation of axonogenesis" EXACT [] synonym: "down-regulation of axonogenesis" EXACT [] synonym: "downregulation of axonogenesis" EXACT [] synonym: "inhibition of axonogenesis" NARROW [] is_a: GO:0010977 ! negative regulation of neuron projection development is_a: GO:0050768 ! negative regulation of neurogenesis is_a: GO:0050770 ! regulation of axonogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007409 ! axonogenesis relationship: negatively_regulates GO:0007409 ! axonogenesis [Term] id: GO:0050772 name: positive regulation of axonogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axonogenesis." [GOC:ai] synonym: "activation of axonogenesis" NARROW [] synonym: "stimulation of axonogenesis" NARROW [] synonym: "up regulation of axonogenesis" EXACT [] synonym: "up-regulation of axonogenesis" EXACT [] synonym: "upregulation of axonogenesis" EXACT [] is_a: GO:0031346 ! positive regulation of cell projection organization is_a: GO:0050769 ! positive regulation of neurogenesis is_a: GO:0050770 ! regulation of axonogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007409 ! axonogenesis relationship: positively_regulates GO:0007409 ! axonogenesis [Term] id: GO:0050776 name: regulation of immune response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006955 ! immune response relationship: regulates GO:0006955 ! immune response [Term] id: GO:0050777 name: negative regulation of immune response namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "down regulation of immune response" EXACT [] synonym: "down-regulation of immune response" EXACT [] synonym: "downregulation of immune response" EXACT [] synonym: "inhibition of immune response" NARROW [] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006955 ! immune response relationship: negatively_regulates GO:0006955 ! immune response [Term] id: GO:0050778 name: positive regulation of immune response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." [GOC:ai] synonym: "stimulation of immune response" NARROW [] synonym: "up regulation of immune response" EXACT [] synonym: "up-regulation of immune response" EXACT [] synonym: "upregulation of immune response" EXACT [] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:0050776 ! regulation of immune response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006955 ! immune response relationship: positively_regulates GO:0006955 ! immune response [Term] id: GO:0050789 name: regulation of biological process namespace: biological_process alt_id: GO:0050791 def: "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." [GOC:ai, GOC:go_curators] subset: gocheck_do_not_annotate subset: goslim_candida subset: goslim_pir synonym: "regulation of physiological process" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008150 ! biological_process relationship: regulates GO:0008150 ! biological_process [Term] id: GO:0050790 name: regulation of catalytic activity namespace: biological_process alt_id: GO:0048552 def: "Any process that modulates the activity of an enzyme." [GOC:ai, GOC:ebc, GOC:vw] subset: goslim_chembl subset: term_scheduled_for_obsoletion synonym: "regulation of enzyme activity" EXACT [] synonym: "regulation of metalloenzyme activity" NARROW [] is_a: GO:0065009 ! regulation of molecular function intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003824 ! catalytic activity relationship: regulates GO:0003824 ! catalytic activity [Term] id: GO:0050793 name: regulation of developmental process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:go_curators] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032502 ! developmental process relationship: regulates GO:0032502 ! developmental process [Term] id: GO:0050794 name: regulation of cellular process namespace: biological_process alt_id: GO:0051244 def: "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." [GOC:go_curators] subset: gocheck_do_not_annotate synonym: "regulation of cellular physiological process" EXACT [] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009987 ! cellular process relationship: regulates GO:0009987 ! cellular process [Term] id: GO:0050795 name: regulation of behavior namespace: biological_process def: "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." [GOC:go_curators, GOC:pr] synonym: "regulation of behaviour" EXACT [] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007610 ! behavior relationship: regulates GO:0007610 ! behavior [Term] id: GO:0050796 name: regulation of insulin secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of insulin." [GOC:ai] is_a: GO:0050708 ! regulation of protein secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030073 ! insulin secretion relationship: regulates GO:0030073 ! insulin secretion [Term] id: GO:0050803 name: regulation of synapse structure or activity namespace: biological_process def: "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai] relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa [Term] id: GO:0050804 name: modulation of chemical synaptic transmission namespace: biological_process def: "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." [GOC:ai] subset: goslim_synapse synonym: "modulation of synaptic transmission" BROAD [] synonym: "regulation of chemical synaptic transmission" EXACT [] synonym: "regulation of synaptic transmission" EXACT [] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0050805 name: negative regulation of synaptic transmission namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "down regulation of synaptic transmission" EXACT [] synonym: "down-regulation of synaptic transmission" EXACT [] synonym: "downregulation of synaptic transmission" EXACT [] synonym: "inhibition of synaptic transmission" NARROW [] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007268 ! chemical synaptic transmission relationship: negatively_regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0050806 name: positive regulation of synaptic transmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." [GOC:ai] synonym: "activation of synaptic transmission" NARROW [] synonym: "stimulation of synaptic transmission" NARROW [] synonym: "up regulation of synaptic transmission" EXACT [] synonym: "up-regulation of synaptic transmission" EXACT [] synonym: "upregulation of synaptic transmission" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007268 ! chemical synaptic transmission relationship: positively_regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0050807 name: regulation of synapse organization namespace: biological_process def: "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of synapse organisation" EXACT [GOC:mah] synonym: "regulation of synapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of synapse structure" EXACT [] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050808 ! synapse organization relationship: part_of GO:0050803 ! regulation of synapse structure or activity relationship: regulates GO:0050808 ! synapse organization [Term] id: GO:0050808 name: synapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." [GOC:ai, GOC:pr] subset: goslim_drosophila subset: goslim_synapse synonym: "synapse development" RELATED [GOC:aruk] synonym: "synapse morphogenesis" RELATED [GOC:BHF] synonym: "synapse organisation" EXACT [] synonym: "synapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0034330 ! cell junction organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0045202 ! synapse relationship: results_in_organization_of GO:0045202 ! synapse [Term] id: GO:0050810 name: regulation of steroid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." [GOC:ai] synonym: "regulation of steroid anabolism" EXACT [] synonym: "regulation of steroid biosynthesis" EXACT [] synonym: "regulation of steroid formation" EXACT [] synonym: "regulation of steroid synthesis" EXACT [] synonym: "regulation of steroidogenesis" EXACT [] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006694 ! steroid biosynthetic process relationship: regulates GO:0006694 ! steroid biosynthetic process [Term] id: GO:0050832 name: defense response to fungus namespace: biological_process alt_id: GO:0009623 alt_id: GO:0009817 alt_id: GO:0042831 def: "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." [GOC:ai] synonym: "defence response to fungi" EXACT [] synonym: "defence response to fungus" EXACT [] synonym: "defense response to fungi" EXACT [] synonym: "defense response to fungus, incompatible interaction" NARROW [] synonym: "resistance response to pathogenic fungi" NARROW [] synonym: "resistance response to pathogenic fungus" NARROW [] synonym: "response to parasitic fungi" NARROW [] synonym: "response to parasitic fungus" NARROW [] is_a: GO:0009620 ! response to fungus is_a: GO:0098542 ! defense response to other organism intersection_of: GO:0006952 ! defense response intersection_of: has_input NCBITaxon:4751 ! Fungi [Term] id: GO:0050863 name: regulation of T cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "regulation of T lymphocyte activation" EXACT [] synonym: "regulation of T-cell activation" EXACT [] synonym: "regulation of T-lymphocyte activation" EXACT [] is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042110 ! T cell activation relationship: regulates GO:0042110 ! T cell activation [Term] id: GO:0050865 name: regulation of cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." [GOC:ai] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001775 ! cell activation relationship: regulates GO:0001775 ! cell activation [Term] id: GO:0050866 name: negative regulation of cell activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." [GOC:ai] synonym: "down regulation of cell activation" EXACT [] synonym: "down-regulation of cell activation" EXACT [] synonym: "downregulation of cell activation" EXACT [] synonym: "inhibition of cell activation" NARROW [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001775 ! cell activation relationship: negatively_regulates GO:0001775 ! cell activation [Term] id: GO:0050867 name: positive regulation of cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of activation." [GOC:ai] synonym: "activation of cell activation" NARROW [] synonym: "stimulation of cell activation" NARROW [] synonym: "up regulation of cell activation" EXACT [] synonym: "up-regulation of cell activation" EXACT [] synonym: "upregulation of cell activation" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0050865 ! regulation of cell activation is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001775 ! cell activation relationship: positively_regulates GO:0001775 ! cell activation [Term] id: GO:0050868 name: negative regulation of T cell activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "down regulation of T cell activation" EXACT [] synonym: "down-regulation of T cell activation" EXACT [] synonym: "downregulation of T cell activation" EXACT [] synonym: "inhibition of T cell activation" NARROW [] synonym: "negative regulation of T lymphocyte activation" EXACT [] synonym: "negative regulation of T-cell activation" EXACT [] synonym: "negative regulation of T-lymphocyte activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051250 ! negative regulation of lymphocyte activation is_a: GO:1903038 ! negative regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042110 ! T cell activation relationship: negatively_regulates GO:0042110 ! T cell activation [Term] id: GO:0050870 name: positive regulation of T cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell activation." [GOC:ai] synonym: "activation of T cell activation" NARROW [] synonym: "positive regulation of T lymphocyte activation" EXACT [] synonym: "positive regulation of T-cell activation" EXACT [] synonym: "positive regulation of T-lymphocyte activation" EXACT [] synonym: "stimulation of T cell activation" NARROW [] synonym: "up regulation of T cell activation" EXACT [] synonym: "up-regulation of T cell activation" EXACT [] synonym: "upregulation of T cell activation" EXACT [] is_a: GO:0050863 ! regulation of T cell activation is_a: GO:0051251 ! positive regulation of lymphocyte activation is_a: GO:1903039 ! positive regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042110 ! T cell activation relationship: positively_regulates GO:0042110 ! T cell activation [Term] id: GO:0050877 name: nervous system process namespace: biological_process def: "A organ system process carried out by any of the organs or tissues of neurological system." [GOC:ai, GOC:mtg_cardio] subset: goslim_agr subset: goslim_chembl subset: goslim_flybase_ribbon subset: goslim_generic subset: goslim_pir synonym: "neurological system process" EXACT [] synonym: "neurophysiological process" EXACT [] synonym: "pan-neural process" RELATED [] is_a: GO:0003008 ! system process intersection_of: GO:0003008 ! system process intersection_of: has_participant UBERON:0001016 ! nervous system relationship: has_participant UBERON:0001016 ! nervous system relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13824" xsd:anyURI [Term] id: GO:0050878 name: regulation of body fluid levels namespace: biological_process def: "Any process that modulates the levels of body fluids." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_pir [Term] id: GO:0050879 name: multicellular organismal movement namespace: biological_process def: "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." [GOC:dph, GOC:mtg_muscle, GOC:tb] subset: goslim_pir is_a: GO:0032501 ! multicellular organismal process [Term] id: GO:0050881 name: musculoskeletal movement namespace: biological_process def: "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." [GOC:dph] is_a: GO:0050879 ! multicellular organismal movement is_a: GO:0050905 ! neuromuscular process [Term] id: GO:0050886 name: endocrine process namespace: biological_process def: "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." [ISBN:0721662544] subset: goslim_generic subset: goslim_pir synonym: "endocrine physiological process" EXACT [] synonym: "endocrine physiology" EXACT [] is_a: GO:0003008 ! system process [Term] id: GO:0050890 name: cognition namespace: biological_process def: "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." [ISBN:0721619908] subset: goslim_drosophila xref: Wikipedia:Cognition is_a: GO:0050877 ! nervous system process [Term] id: GO:0050896 name: response to stimulus namespace: biological_process alt_id: GO:0051869 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." [GOC:ai, GOC:bf] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir subset: prokaryote_subset synonym: "physiological response to stimulus" EXACT [] is_a: GO:0008150 ! biological_process [Term] id: GO:0050900 name: leukocyte migration namespace: biological_process def: "The movement of a leukocyte within or between different tissues and organs of the body." [GOC:add, ISBN:0781735149, PMID:14680625, PMID:14708592, PMID:7507411, PMID:8600538] synonym: "immune cell migration" EXACT [] synonym: "immune cell trafficking" EXACT [] synonym: "leucocyte migration" EXACT [] synonym: "leucocyte trafficking" EXACT [] synonym: "leukocyte trafficking" EXACT [] is_a: GO:0002376 ! immune system process is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: results_in_movement_of CL:0000738 ! leukocyte [Term] id: GO:0050905 name: neuromuscular process namespace: biological_process def: "Any process pertaining to the functions of the nervous and muscular systems of an organism." [GOC:ai] synonym: "neuromotor process" EXACT [] synonym: "neuromuscular physiological process" EXACT [] is_a: GO:0050877 ! nervous system process [Term] id: GO:0050906 name: detection of stimulus involved in sensory perception namespace: biological_process def: "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph] synonym: "sensory detection of stimulus" EXACT [] synonym: "sensory perception, sensory transduction of stimulus" EXACT [] synonym: "sensory perception, stimulus detection" EXACT [] synonym: "sensory transduction" EXACT [] xref: Wikipedia:Transduction_(physiology) is_a: GO:0051606 ! detection of stimulus intersection_of: GO:0051606 ! detection of stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0007600 ! sensory perception [Term] id: GO:0050907 name: detection of chemical stimulus involved in sensory perception namespace: biological_process def: "The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of chemical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus" EXACT [] synonym: "sensory transduction of chemical stimulus during sensory perception" EXACT [] is_a: GO:0009593 ! detection of chemical stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0007606 ! sensory perception of chemical stimulus [Term] id: GO:0050908 name: detection of light stimulus involved in visual perception namespace: biological_process def: "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "sensory detection of light during visual perception" EXACT [] synonym: "sensory detection of light stimulus during visual perception" EXACT [] synonym: "sensory transduction of light during visual perception" EXACT [] synonym: "sensory transduction of light stimulus during visual perception" EXACT [] synonym: "visual perception, detection of light stimulus" EXACT [] synonym: "visual perception, sensory transduction during perception of light" EXACT [] synonym: "visual perception, sensory transduction of light stimulus" EXACT [] is_a: GO:0009584 ! detection of visible light is_a: GO:0050962 ! detection of light stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: part_of GO:0007601 ! visual perception relationship: part_of GO:0007601 ! visual perception [Term] id: GO:0050909 name: sensory perception of taste namespace: biological_process def: "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process." [GOC:ai] synonym: "gustation" EXACT [] synonym: "sense of taste" EXACT [] synonym: "taste" EXACT [] synonym: "taste perception" EXACT [] xref: Wikipedia:Taste is_a: GO:0007606 ! sensory perception of chemical stimulus [Term] id: GO:0050910 name: detection of mechanical stimulus involved in sensory perception of sound namespace: biological_process alt_id: GO:0009592 alt_id: GO:0055128 def: "The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal." [GOC:ai] synonym: "detection of sound" EXACT [] synonym: "hearing, sensory transduction of sound" EXACT [] synonym: "perception of sound, detection of mechanical stimulus" EXACT [] synonym: "perception of sound, sensory detection of mechanical stimulus" EXACT [] synonym: "perception of sound, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during perception of sound" EXACT [] synonym: "sensory transduction of mechanical stimulus during perception of sound" EXACT [] synonym: "sensory transduction of sound" EXACT [] is_a: GO:0050877 ! nervous system process is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0007605 ! sensory perception of sound relationship: part_of GO:0007605 ! sensory perception of sound [Term] id: GO:0050911 name: detection of chemical stimulus involved in sensory perception of smell namespace: biological_process def: "The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "perception of smell, detection of chemical stimulus" EXACT [] synonym: "perception of smell, sensory detection of chemical stimulus" EXACT [] synonym: "perception of smell, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of smell" EXACT [] synonym: "sensory detection of scent" EXACT [] synonym: "sensory detection of smell" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of smell" EXACT [] synonym: "sensory transduction of scent" EXACT [] synonym: "sensory transduction of smell" EXACT [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0007608 ! sensory perception of smell relationship: part_of GO:0007608 ! sensory perception of smell [Term] id: GO:0050912 name: detection of chemical stimulus involved in sensory perception of taste namespace: biological_process def: "The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "perception of taste, detection of chemical stimulus" EXACT [] synonym: "perception of taste, sensory detection of chemical stimulus" EXACT [] synonym: "perception of taste, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of taste" EXACT [] synonym: "sensory detection of taste" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of taste" EXACT [] synonym: "sensory transduction of taste" EXACT [] synonym: "taste perception" BROAD [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0050909 ! sensory perception of taste relationship: part_of GO:0050909 ! sensory perception of taste [Term] id: GO:0050931 name: pigment cell differentiation namespace: biological_process alt_id: GO:0043357 alt_id: GO:0043358 def: "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." [GOC:dgh] comment: Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore. synonym: "chromatophore differentiation" EXACT [] synonym: "pigmented cell differentiation" EXACT [] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000147 ! pigment cell relationship: part_of GO:0048066 ! developmental pigmentation relationship: results_in_acquisition_of_features_of CL:0000147 ! pigment cell [Term] id: GO:0050932 name: regulation of pigment cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." [GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050931 ! pigment cell differentiation relationship: regulates GO:0050931 ! pigment cell differentiation [Term] id: GO:0050941 name: negative regulation of pigment cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "down regulation of pigment cell differentiation" EXACT [] synonym: "down-regulation of pigment cell differentiation" EXACT [] synonym: "downregulation of pigment cell differentiation" EXACT [] synonym: "inhibition of pigment cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0048086 ! negative regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050931 ! pigment cell differentiation relationship: negatively_regulates GO:0050931 ! pigment cell differentiation [Term] id: GO:0050942 name: positive regulation of pigment cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." [GOC:ai] synonym: "activation of pigment cell differentiation" NARROW [] synonym: "stimulation of pigment cell differentiation" NARROW [] synonym: "up regulation of pigment cell differentiation" EXACT [] synonym: "up-regulation of pigment cell differentiation" EXACT [] synonym: "upregulation of pigment cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0048087 ! positive regulation of developmental pigmentation is_a: GO:0050932 ! regulation of pigment cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050931 ! pigment cell differentiation relationship: positively_regulates GO:0050931 ! pigment cell differentiation [Term] id: GO:0050952 name: sensory perception of electrical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050953 name: sensory perception of light stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050954 name: sensory perception of mechanical stimulus namespace: biological_process def: "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." [GOC:ai] synonym: "chemi-mechanical coupling" RELATED [] synonym: "mechanosensory perception" EXACT [] synonym: "perception of mechanical stimulus" EXACT [] is_a: GO:0007600 ! sensory perception [Term] id: GO:0050956 name: electroception namespace: biological_process def: "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location." [GOC:ai, PMID:10210663, Wikipedia:Electroreception] synonym: "electroception sense" EXACT [] synonym: "electroceptive sense" EXACT [] xref: Wikipedia:Electroreception is_a: GO:0050952 ! sensory perception of electrical stimulus [Term] id: GO:0050962 name: detection of light stimulus involved in sensory perception namespace: biological_process def: "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." [GOC:ai, GOC:dos] synonym: "sensory detection of light stimulus" EXACT [] synonym: "sensory detection of light stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of light stimulus" EXACT [] synonym: "sensory perception, sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus" EXACT [] synonym: "sensory transduction of light stimulus during sensory perception" EXACT [] is_a: GO:0009583 ! detection of light stimulus is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0009583 ! detection of light stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050953 ! sensory perception of light stimulus [Term] id: GO:0050963 name: detection of electrical stimulus involved in sensory perception namespace: biological_process def: "The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of electrical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus" EXACT [] synonym: "sensory transduction of electrical stimulus during sensory perception" EXACT [] is_a: GO:0050906 ! detection of stimulus involved in sensory perception is_a: GO:0050981 ! detection of electrical stimulus intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050952 ! sensory perception of electrical stimulus [Term] id: GO:0050964 name: detection of electrical stimulus involved in electroception namespace: biological_process def: "The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "detection of electrical stimulus during electroreception" RELATED [GOC:dph, GOC:tb] synonym: "electroception, detection of electrical stimulus" EXACT [] synonym: "electroception, sensory detection of electrical stimulus" EXACT [] synonym: "electroception, sensory transduction" EXACT [] synonym: "electroception, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during electroception" RELATED [] synonym: "sensory transduction of electrical stimulus during electroception" RELATED [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0050956 ! electroception relationship: part_of GO:0050956 ! electroception [Term] id: GO:0050966 name: detection of mechanical stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "mechanical nociception" RELATED [GOC:pr] synonym: "perception of pain, detection of mechanical stimulus" EXACT [] synonym: "perception of pain, sensory detection of mechanical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during perception of pain" EXACT [] synonym: "sensory transduction of mechanical stimulus during perception of pain" EXACT [] is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050967 name: detection of electrical stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "detection of electrical stimulus during sensory perception of pain" RELATED [GOC:dph, GOC:tb] synonym: "perception of pain, detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory detection of electrical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of electrical stimulus" EXACT [] synonym: "sensory detection of electrical stimulus during perception of pain" RELATED [] synonym: "sensory transduction of electrical stimulus during perception of pain" RELATED [] is_a: GO:0050963 ! detection of electrical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0050981 ! detection of electrical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050968 name: detection of chemical stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal." [GOC:ai] synonym: "chemical nociception" RELATED [GOC:pr] synonym: "perception of pain, detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory detection of chemical stimulus" EXACT [] synonym: "perception of pain, sensory transduction of chemical stimulus" EXACT [] synonym: "sensory detection of chemical stimulus during perception of pain" EXACT [] synonym: "sensory transduction of chemical stimulus during perception of pain" EXACT [] is_a: GO:0050907 ! detection of chemical stimulus involved in sensory perception is_a: GO:0062149 ! detection of stimulus involved in sensory perception of pain intersection_of: GO:0009593 ! detection of chemical stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain [Term] id: GO:0050974 name: detection of mechanical stimulus involved in sensory perception namespace: biological_process def: "The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception." [GOC:ai, GOC:dos] synonym: "sensory detection of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during sensory perception" EXACT [] synonym: "sensory perception, sensory detection of mechanical stimulus" EXACT [] synonym: "sensory perception, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory transduction of mechanical stimulus during sensory perception" EXACT [] is_a: GO:0050906 ! detection of stimulus involved in sensory perception is_a: GO:0050982 ! detection of mechanical stimulus intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0007600 ! sensory perception relationship: part_of GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0050975 name: sensory perception of touch namespace: biological_process def: "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." [GOC:ai] synonym: "perception of touch" EXACT [] synonym: "tactile sense" EXACT [] synonym: "taction" EXACT [] synonym: "tactition" EXACT [] xref: Wikipedia:Touch is_a: GO:0050954 ! sensory perception of mechanical stimulus [Term] id: GO:0050976 name: detection of mechanical stimulus involved in sensory perception of touch namespace: biological_process def: "The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] synonym: "perception of touch, detection of mechanical stimulus" EXACT [] synonym: "perception of touch, sensory detection of mechanical stimulus" EXACT [] synonym: "perception of touch, sensory transduction of mechanical stimulus" EXACT [] synonym: "sensory detection of mechanical stimulus during perception of touch" EXACT [] synonym: "sensory transduction of mechanical stimulus during perception of touch" EXACT [] synonym: "tactition, sensory detection of mechanical stimulus" EXACT [] is_a: GO:0050974 ! detection of mechanical stimulus involved in sensory perception intersection_of: GO:0050982 ! detection of mechanical stimulus intersection_of: part_of GO:0050975 ! sensory perception of touch relationship: part_of GO:0050975 ! sensory perception of touch [Term] id: GO:0050981 name: detection of electrical stimulus namespace: biological_process def: "The series of events by which an electrical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] is_a: GO:0009582 ! detection of abiotic stimulus is_a: GO:0051602 ! response to electrical stimulus [Term] id: GO:0050982 name: detection of mechanical stimulus namespace: biological_process def: "The series of events by which a mechanical stimulus is received and converted into a molecular signal." [GOC:ai, GOC:dos] is_a: GO:0009581 ! detection of external stimulus is_a: GO:0009582 ! detection of abiotic stimulus is_a: GO:0009612 ! response to mechanical stimulus [Term] id: GO:0050994 name: regulation of lipid catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "regulation of lipid breakdown" EXACT [] synonym: "regulation of lipid catabolism" EXACT [] synonym: "regulation of lipid degradation" EXACT [] is_a: GO:0009894 ! regulation of catabolic process is_a: GO:0019216 ! regulation of lipid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016042 ! lipid catabolic process relationship: regulates GO:0016042 ! lipid catabolic process [Term] id: GO:0050995 name: negative regulation of lipid catabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "down regulation of lipid catabolic process" EXACT [] synonym: "down-regulation of lipid catabolic process" EXACT [] synonym: "downregulation of lipid catabolic process" EXACT [] synonym: "inhibition of lipid catabolic process" NARROW [] synonym: "negative regulation of lipid breakdown" EXACT [] synonym: "negative regulation of lipid catabolism" EXACT [] synonym: "negative regulation of lipid degradation" EXACT [] is_a: GO:0009895 ! negative regulation of catabolic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016042 ! lipid catabolic process relationship: negatively_regulates GO:0016042 ! lipid catabolic process [Term] id: GO:0050996 name: positive regulation of lipid catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." [GOC:ai] synonym: "activation of lipid catabolic process" NARROW [] synonym: "positive regulation of lipid breakdown" EXACT [] synonym: "positive regulation of lipid catabolism" EXACT [] synonym: "positive regulation of lipid degradation" EXACT [] synonym: "stimulation of lipid catabolic process" NARROW [] synonym: "up regulation of lipid catabolic process" EXACT [] synonym: "up-regulation of lipid catabolic process" EXACT [] synonym: "upregulation of lipid catabolic process" EXACT [] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0045834 ! positive regulation of lipid metabolic process is_a: GO:0050994 ! regulation of lipid catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016042 ! lipid catabolic process relationship: positively_regulates GO:0016042 ! lipid catabolic process [Term] id: GO:0051017 name: actin filament bundle assembly namespace: biological_process alt_id: GO:0045011 def: "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." [GOC:ai] synonym: "actin bundling activity" RELATED [] synonym: "actin cable assembly" RELATED [GOC:mah] synonym: "actin cable formation" RELATED [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061572 ! actin filament bundle organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032432 ! actin filament bundle relationship: results_in_assembly_of GO:0032432 ! actin filament bundle [Term] id: GO:0051027 name: DNA transport namespace: biological_process def: "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0050657 ! nucleic acid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid [Term] id: GO:0051032 name: nucleic acid transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." [GOC:ai] is_a: GO:0015932 ! nucleobase-containing compound transmembrane transporter activity is_a: GO:0022884 ! macromolecule transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33696 ! nucleic acid relationship: has_primary_input CHEBI:33696 ! nucleic acid relationship: part_of GO:0050657 ! nucleic acid transport [Term] id: GO:0051033 name: RNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." [GOC:ai] xref: Reactome:R-HSA-203906 "Exportin complex translocates pre-miRNA to cytosol" is_a: GO:0051032 ! nucleic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: has_primary_input CHEBI:33697 ! ribonucleic acid relationship: part_of GO:0050658 ! RNA transport [Term] id: GO:0051035 name: DNA transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." [GOC:ai] is_a: GO:0051032 ! nucleic acid transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_input CHEBI:16991 ! deoxyribonucleic acid relationship: part_of GO:0051027 ! DNA transport [Term] id: GO:0051046 name: regulation of secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046903 ! secretion relationship: regulates GO:0046903 ! secretion [Term] id: GO:0051047 name: positive regulation of secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "activation of secretion" NARROW [] synonym: "stimulation of secretion" NARROW [] synonym: "up regulation of secretion" EXACT [] synonym: "up-regulation of secretion" EXACT [] synonym: "upregulation of secretion" EXACT [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051050 ! positive regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046903 ! secretion relationship: positively_regulates GO:0046903 ! secretion [Term] id: GO:0051048 name: negative regulation of secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." [GOC:ai] synonym: "down regulation of secretion" EXACT [] synonym: "down-regulation of secretion" EXACT [] synonym: "downregulation of secretion" EXACT [] synonym: "inhibition of secretion" NARROW [] is_a: GO:0051046 ! regulation of secretion is_a: GO:0051051 ! negative regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046903 ! secretion relationship: negatively_regulates GO:0046903 ! secretion [Term] id: GO:0051049 name: regulation of transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] subset: goslim_yeast is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006810 ! transport relationship: regulates GO:0006810 ! transport [Term] id: GO:0051050 name: positive regulation of transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of transport" NARROW [] synonym: "stimulation of transport" NARROW [] synonym: "up regulation of transport" EXACT [] synonym: "up-regulation of transport" EXACT [] synonym: "upregulation of transport" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006810 ! transport relationship: positively_regulates GO:0006810 ! transport [Term] id: GO:0051051 name: negative regulation of transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of transport" EXACT [] synonym: "down-regulation of transport" EXACT [] synonym: "downregulation of transport" EXACT [] synonym: "inhibition of transport" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006810 ! transport relationship: negatively_regulates GO:0006810 ! transport [Term] id: GO:0051052 name: regulation of DNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] subset: goslim_yeast synonym: "regulation of DNA metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006259 ! DNA metabolic process relationship: regulates GO:0006259 ! DNA metabolic process [Term] id: GO:0051053 name: negative regulation of DNA metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] synonym: "down regulation of DNA metabolic process" EXACT [] synonym: "down-regulation of DNA metabolic process" EXACT [] synonym: "downregulation of DNA metabolic process" EXACT [] synonym: "inhibition of DNA metabolic process" NARROW [] synonym: "negative regulation of DNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006259 ! DNA metabolic process relationship: negatively_regulates GO:0006259 ! DNA metabolic process [Term] id: GO:0051054 name: positive regulation of DNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." [GOC:ai] synonym: "activation of DNA metabolic process" NARROW [] synonym: "positive regulation of DNA metabolism" EXACT [] synonym: "stimulation of DNA metabolic process" NARROW [] synonym: "up regulation of DNA metabolic process" EXACT [] synonym: "up-regulation of DNA metabolic process" EXACT [] synonym: "upregulation of DNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006259 ! DNA metabolic process relationship: positively_regulates GO:0006259 ! DNA metabolic process [Term] id: GO:0051055 name: negative regulation of lipid biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." [GOC:ai] synonym: "down regulation of lipid biosynthetic process" EXACT [] synonym: "down-regulation of lipid biosynthetic process" EXACT [] synonym: "downregulation of lipid biosynthetic process" EXACT [] synonym: "inhibition of lipid biosynthetic process" NARROW [] synonym: "negative regulation of lipid anabolism" EXACT [] synonym: "negative regulation of lipid biosynthesis" EXACT [] synonym: "negative regulation of lipid formation" EXACT [] synonym: "negative regulation of lipid synthesis" EXACT [] synonym: "negative regulation of lipogenesis" EXACT [GOC:sl] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0045833 ! negative regulation of lipid metabolic process is_a: GO:0046890 ! regulation of lipid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008610 ! lipid biosynthetic process relationship: negatively_regulates GO:0008610 ! lipid biosynthetic process [Term] id: GO:0051078 name: meiotic nuclear membrane disassembly namespace: biological_process def: "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." [GOC:bf] synonym: "meiotic nuclear envelope breakdown" RELATED [] synonym: "meiotic nuclear envelope catabolism" RELATED [] synonym: "meiotic nuclear envelope degradation" RELATED [] synonym: "meiotic nuclear envelope disassembly" RELATED [] is_a: GO:0051081 ! nuclear membrane disassembly is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0051080 name: meiosis II nuclear membrane disassembly namespace: biological_process def: "The controlled breakdown of the nuclear membranes during the second division of meiosis." [GOC:bf] synonym: "meiosis II nuclear envelope breakdown" RELATED [] synonym: "meiosis II nuclear envelope catabolism" RELATED [] synonym: "meiosis II nuclear envelope degradation" RELATED [] synonym: "meiosis II nuclear envelope disassembly" RELATED [] is_a: GO:0051078 ! meiotic nuclear membrane disassembly intersection_of: GO:0051081 ! nuclear membrane disassembly intersection_of: part_of GO:0007135 ! meiosis II relationship: part_of GO:0007135 ! meiosis II [Term] id: GO:0051081 name: nuclear membrane disassembly namespace: biological_process def: "The controlled breakdown of the nuclear membranes, for example during cellular division." [GOC:ai] synonym: "nuclear envelope breakdown" RELATED [] synonym: "nuclear envelope catabolism" RELATED [] synonym: "nuclear envelope degradation" RELATED [] synonym: "nuclear envelope disassembly" RELATED [] is_a: GO:0030397 ! membrane disassembly is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0031965 ! nuclear membrane relationship: results_in_disassembly_of GO:0031965 ! nuclear membrane [Term] id: GO:0051093 name: negative regulation of developmental process namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "down regulation of developmental process" EXACT [] synonym: "down-regulation of developmental process" EXACT [] synonym: "downregulation of developmental process" EXACT [] synonym: "inhibition of developmental process" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032502 ! developmental process relationship: negatively_regulates GO:0032502 ! developmental process [Term] id: GO:0051094 name: positive regulation of developmental process namespace: biological_process def: "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." [GOC:ai] synonym: "activation of developmental process" NARROW [] synonym: "stimulation of developmental process" NARROW [] synonym: "up regulation of developmental process" EXACT [] synonym: "up-regulation of developmental process" EXACT [] synonym: "upregulation of developmental process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032502 ! developmental process relationship: positively_regulates GO:0032502 ! developmental process [Term] id: GO:0051119 name: sugar transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." [GOC:ai, GOC:mtg_transport, ISBN:0815340729] synonym: "sugar/polyol channel activity" NARROW [] xref: Reactome:R-HSA-428779 "GLUT7 and GLUT11 transport glucose and fructose" xref: Reactome:R-HSA-8875902 "SLC45A3 transports Glc from extracellular region to cytosol" xref: Reactome:R-HSA-8876319 "SLC50A1 transports Glc from cytosol to extracellular region" is_a: GO:0015144 ! carbohydrate transmembrane transporter activity [Term] id: GO:0051128 name: regulation of cellular component organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "regulation of cell organisation" RELATED [GOC:mah] synonym: "regulation of cell organization" RELATED [GOC:mah] synonym: "regulation of cellular component organisation" EXACT [] synonym: "regulation of cellular component organization and biogenesis" RELATED [GOC:mah] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016043 ! cellular component organization relationship: regulates GO:0016043 ! cellular component organization [Term] id: GO:0051129 name: negative regulation of cellular component organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "down regulation of cell organization" EXACT [] synonym: "down-regulation of cell organization" EXACT [] synonym: "downregulation of cell organization" EXACT [] synonym: "inhibition of cell organization" NARROW [] synonym: "negative regulation of cell organisation" RELATED [GOC:mah] synonym: "negative regulation of cellular component organization and biogenesis" RELATED [GOC:mah] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016043 ! cellular component organization relationship: negatively_regulates GO:0016043 ! cellular component organization [Term] id: GO:0051130 name: positive regulation of cellular component organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." [GOC:ai] synonym: "activation of cell organization" NARROW [] synonym: "positive regulation of cell organisation" EXACT [] synonym: "positive regulation of cellular component organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cell organization" NARROW [] synonym: "up regulation of cell organization" EXACT [] synonym: "up-regulation of cell organization" EXACT [] synonym: "upregulation of cell organization" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016043 ! cellular component organization relationship: positively_regulates GO:0016043 ! cellular component organization [Term] id: GO:0051145 name: smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." [CL:0000192, GOC:ai] synonym: "nonstriated muscle cell differentiation" EXACT [] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000192 ! smooth muscle cell relationship: results_in_acquisition_of_features_of CL:0000192 ! smooth muscle cell [Term] id: GO:0051146 name: striated muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." [CL:0000737, GOC:ai] synonym: "voluntary muscle cell differentiation" NARROW [] is_a: GO:0042692 ! muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000737 ! striated muscle cell relationship: results_in_acquisition_of_features_of CL:0000737 ! striated muscle cell [Term] id: GO:0051147 name: regulation of muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042692 ! muscle cell differentiation relationship: regulates GO:0042692 ! muscle cell differentiation [Term] id: GO:0051148 name: negative regulation of muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "down regulation of muscle cell differentiation" EXACT [] synonym: "down-regulation of muscle cell differentiation" EXACT [] synonym: "downregulation of muscle cell differentiation" EXACT [] synonym: "inhibition of muscle cell differentiation" NARROW [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042692 ! muscle cell differentiation relationship: negatively_regulates GO:0042692 ! muscle cell differentiation [Term] id: GO:0051149 name: positive regulation of muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." [CL:0000187, GOC:ai] synonym: "activation of muscle cell differentiation" NARROW [] synonym: "stimulation of muscle cell differentiation" NARROW [] synonym: "up regulation of muscle cell differentiation" EXACT [] synonym: "up-regulation of muscle cell differentiation" EXACT [] synonym: "upregulation of muscle cell differentiation" EXACT [] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042692 ! muscle cell differentiation relationship: positively_regulates GO:0042692 ! muscle cell differentiation [Term] id: GO:0051150 name: regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051145 ! smooth muscle cell differentiation relationship: regulates GO:0051145 ! smooth muscle cell differentiation [Term] id: GO:0051151 name: negative regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "down regulation of smooth muscle cell differentiation" EXACT [] synonym: "down-regulation of smooth muscle cell differentiation" EXACT [] synonym: "downregulation of smooth muscle cell differentiation" EXACT [] synonym: "inhibition of smooth muscle cell differentiation" NARROW [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051145 ! smooth muscle cell differentiation relationship: negatively_regulates GO:0051145 ! smooth muscle cell differentiation [Term] id: GO:0051152 name: positive regulation of smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." [CL:0000192, GOC:ai] synonym: "activation of smooth muscle cell differentiation" NARROW [] synonym: "stimulation of smooth muscle cell differentiation" NARROW [] synonym: "up regulation of smooth muscle cell differentiation" EXACT [] synonym: "up-regulation of smooth muscle cell differentiation" EXACT [] synonym: "upregulation of smooth muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051145 ! smooth muscle cell differentiation relationship: positively_regulates GO:0051145 ! smooth muscle cell differentiation [Term] id: GO:0051153 name: regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] is_a: GO:0051147 ! regulation of muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051146 ! striated muscle cell differentiation relationship: regulates GO:0051146 ! striated muscle cell differentiation [Term] id: GO:0051154 name: negative regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "down regulation of striated muscle cell differentiation" EXACT [] synonym: "down-regulation of striated muscle cell differentiation" EXACT [] synonym: "downregulation of striated muscle cell differentiation" EXACT [] synonym: "inhibition of striated muscle cell differentiation" NARROW [] is_a: GO:0051148 ! negative regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051146 ! striated muscle cell differentiation relationship: negatively_regulates GO:0051146 ! striated muscle cell differentiation [Term] id: GO:0051155 name: positive regulation of striated muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." [CL:0000737, GOC:ai] synonym: "activation of striated muscle cell differentiation" NARROW [] synonym: "stimulation of striated muscle cell differentiation" NARROW [] synonym: "up regulation of striated muscle cell differentiation" EXACT [] synonym: "up-regulation of striated muscle cell differentiation" EXACT [] synonym: "upregulation of striated muscle cell differentiation" EXACT [] is_a: GO:0051149 ! positive regulation of muscle cell differentiation is_a: GO:0051153 ! regulation of striated muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051146 ! striated muscle cell differentiation relationship: positively_regulates GO:0051146 ! striated muscle cell differentiation [Term] id: GO:0051169 name: nuclear transport namespace: biological_process def: "The directed movement of substances into, out of, or within the nucleus." [GOC:ai] subset: goslim_yeast synonym: "nucleus transport" EXACT [] xref: Wikipedia:Nuclear_transport is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure intersection_of: results_in_transport_to_from_or_in GO:0005634 ! nucleus relationship: results_in_transport_to_from_or_in GO:0005634 ! nucleus [Term] id: GO:0051171 name: regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "regulation of nitrogen metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006807 ! nitrogen compound metabolic process relationship: regulates GO:0006807 ! nitrogen compound metabolic process [Term] id: GO:0051172 name: negative regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "down regulation of nitrogen metabolic process" EXACT [] synonym: "down-regulation of nitrogen metabolic process" EXACT [] synonym: "downregulation of nitrogen metabolic process" EXACT [] synonym: "inhibition of nitrogen metabolic process" NARROW [] synonym: "negative regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "negative regulation of nitrogen metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006807 ! nitrogen compound metabolic process relationship: negatively_regulates GO:0006807 ! nitrogen compound metabolic process [Term] id: GO:0051173 name: positive regulation of nitrogen compound metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." [GOC:ai, GOC:tb] synonym: "activation of nitrogen metabolic process" NARROW [] synonym: "positive regulation of nitrogen metabolic process" EXACT [GOC:tb] synonym: "positive regulation of nitrogen metabolism" EXACT [] synonym: "stimulation of nitrogen metabolic process" NARROW [] synonym: "up regulation of nitrogen metabolic process" EXACT [] synonym: "up-regulation of nitrogen metabolic process" EXACT [] synonym: "upregulation of nitrogen metabolic process" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006807 ! nitrogen compound metabolic process relationship: positively_regulates GO:0006807 ! nitrogen compound metabolic process [Term] id: GO:0051174 name: regulation of phosphorus metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." [GOC:ai] synonym: "regulation of phosphorus metabolism" EXACT [] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006793 ! phosphorus metabolic process relationship: regulates GO:0006793 ! phosphorus metabolic process [Term] id: GO:0051175 name: negative regulation of sulfur metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] synonym: "down regulation of sulfur metabolic process" EXACT [] synonym: "down-regulation of sulfur metabolic process" EXACT [] synonym: "downregulation of sulfur metabolic process" EXACT [] synonym: "inhibition of sulfur metabolic process" NARROW [] synonym: "negative regulation of sulfur metabolism" EXACT [] synonym: "negative regulation of sulphur metabolic process" EXACT [] synonym: "negative regulation of sulphur metabolism" EXACT [] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0042762 ! regulation of sulfur metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006790 ! sulfur compound metabolic process relationship: negatively_regulates GO:0006790 ! sulfur compound metabolic process [Term] id: GO:0051176 name: positive regulation of sulfur metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." [GOC:ai] synonym: "activation of sulfur metabolic process" NARROW [] synonym: "positive regulation of sulfur metabolism" EXACT [] synonym: "positive regulation of sulphur metabolic process" EXACT [] synonym: "positive regulation of sulphur metabolism" EXACT [] synonym: "stimulation of sulfur metabolic process" NARROW [] synonym: "up regulation of sulfur metabolic process" EXACT [] synonym: "up-regulation of sulfur metabolic process" EXACT [] synonym: "upregulation of sulfur metabolic process" EXACT [] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0042762 ! regulation of sulfur metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006790 ! sulfur compound metabolic process relationship: positively_regulates GO:0006790 ! sulfur compound metabolic process [Term] id: GO:0051179 name: localization namespace: biological_process alt_id: GO:1902578 def: "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." [GOC:ai, GOC:dos] subset: goslim_pir synonym: "establishment and maintenance of cellular component location" NARROW [] synonym: "establishment and maintenance of localization" EXACT [] synonym: "establishment and maintenance of position" EXACT [] synonym: "establishment and maintenance of substance location" NARROW [] synonym: "establishment and maintenance of substrate location" NARROW [] synonym: "localisation" EXACT [GOC:mah] synonym: "single organism localization" RELATED [GOC:TermGenie] synonym: "single-organism localization" RELATED [] is_a: GO:0008150 ! biological_process created_by: jl creation_date: 2013-12-18T13:51:04Z [Term] id: GO:0051216 name: cartilage development namespace: biological_process def: "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:cjm, PMID:23251424] synonym: "cartilage biogenesis" EXACT [] synonym: "cartilage biosynthesis" EXACT [] synonym: "cartilage element development" EXACT [] synonym: "cartilage formation" EXACT [] synonym: "cartilage organ development" EXACT [] synonym: "chondrogenesis" EXACT [] xref: Wikipedia:Chondrogenesis is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007844 ! cartilage element relationship: part_of GO:0001501 ! skeletal system development relationship: part_of GO:0061448 ! connective tissue development relationship: results_in_development_of UBERON:0007844 ! cartilage element [Term] id: GO:0051222 name: positive regulation of protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of protein transport" NARROW [] synonym: "stimulation of protein transport" NARROW [] synonym: "up regulation of protein transport" EXACT [] synonym: "up-regulation of protein transport" EXACT [] synonym: "upregulation of protein transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1904951 ! positive regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015031 ! protein transport relationship: positively_regulates GO:0015031 ! protein transport [Term] id: GO:0051223 name: regulation of protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015031 ! protein transport relationship: regulates GO:0015031 ! protein transport [Term] id: GO:0051224 name: negative regulation of protein transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of protein transport" EXACT [] synonym: "down-regulation of protein transport" EXACT [] synonym: "downregulation of protein transport" EXACT [] synonym: "inhibition of protein transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051223 ! regulation of protein transport is_a: GO:1904950 ! negative regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015031 ! protein transport relationship: negatively_regulates GO:0015031 ! protein transport [Term] id: GO:0051234 name: establishment of localization namespace: biological_process def: "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos] subset: goslim_agr subset: goslim_flybase_ribbon subset: goslim_mouse subset: goslim_pir synonym: "establishment of localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization [Term] id: GO:0051236 name: establishment of RNA localization namespace: biological_process def: "The directed movement of RNA to a specific location." [GOC:ai] synonym: "establishment of RNA localisation" EXACT [GOC:mah] synonym: "RNA positioning" EXACT [] synonym: "RNA recruitment" EXACT [] is_a: GO:0051234 ! establishment of localization relationship: part_of GO:0006403 ! RNA localization [Term] id: GO:0051239 name: regulation of multicellular organismal process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai, GOC:dph, GOC:tb] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032501 ! multicellular organismal process relationship: regulates GO:0032501 ! multicellular organismal process [Term] id: GO:0051240 name: positive regulation of multicellular organismal process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "activation of multicellular organismal process" NARROW [] synonym: "stimulation of multicellular organismal process" NARROW [] synonym: "up regulation of multicellular organismal process" EXACT [] synonym: "up-regulation of multicellular organismal process" EXACT [] synonym: "upregulation of multicellular organismal process" EXACT [] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032501 ! multicellular organismal process relationship: positively_regulates GO:0032501 ! multicellular organismal process [Term] id: GO:0051241 name: negative regulation of multicellular organismal process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." [GOC:ai] synonym: "down regulation of multicellular organismal process" EXACT [] synonym: "down-regulation of multicellular organismal process" EXACT [] synonym: "downregulation of multicellular organismal process" EXACT [] synonym: "inhibition of multicellular organismal process" NARROW [] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032501 ! multicellular organismal process relationship: negatively_regulates GO:0032501 ! multicellular organismal process [Term] id: GO:0051246 name: regulation of protein metabolic process namespace: biological_process alt_id: GO:0032268 def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "regulation of cellular protein metabolic process" RELATED [] synonym: "regulation of cellular protein metabolism" RELATED [] synonym: "regulation of protein metabolism" EXACT [] is_a: GO:0051171 ! regulation of nitrogen compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019538 ! protein metabolic process relationship: regulates GO:0019538 ! protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051247 name: positive regulation of protein metabolic process namespace: biological_process alt_id: GO:0032270 def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." [GOC:ai] synonym: "activation of cellular protein metabolic process" NARROW [] synonym: "activation of protein metabolic process" NARROW [] synonym: "positive regulation of cellular protein metabolic process" EXACT [] synonym: "positive regulation of cellular protein metabolism" EXACT [] synonym: "positive regulation of protein metabolism" EXACT [] synonym: "stimulation of cellular protein metabolic process" NARROW [] synonym: "stimulation of protein metabolic process" NARROW [] synonym: "up regulation of cellular protein metabolic process" EXACT [] synonym: "up regulation of protein metabolic process" EXACT [] synonym: "up-regulation of cellular protein metabolic process" EXACT [] synonym: "up-regulation of protein metabolic process" EXACT [] synonym: "upregulation of cellular protein metabolic process" EXACT [] synonym: "upregulation of protein metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019538 ! protein metabolic process relationship: positively_regulates GO:0019538 ! protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051248 name: negative regulation of protein metabolic process namespace: biological_process alt_id: GO:0032269 def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." [GOC:ai] synonym: "down regulation of cellular protein metabolic process" EXACT [] synonym: "down regulation of protein metabolic process" EXACT [] synonym: "down-regulation of cellular protein metabolic process" EXACT [] synonym: "down-regulation of protein metabolic process" EXACT [] synonym: "downregulation of cellular protein metabolic process" EXACT [] synonym: "downregulation of protein metabolic process" EXACT [] synonym: "inhibition of cellular protein metabolic process" NARROW [] synonym: "inhibition of protein metabolic process" NARROW [] synonym: "negative regulation of cellular protein metabolic process" EXACT [] synonym: "negative regulation of cellular protein metabolism" EXACT [] synonym: "negative regulation of protein metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019538 ! protein metabolic process relationship: negatively_regulates GO:0019538 ! protein metabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23112" xsd:anyURI [Term] id: GO:0051249 name: regulation of lymphocyte activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte activation." [GOC:ai] is_a: GO:0002694 ! regulation of leukocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0046649 ! lymphocyte activation relationship: regulates GO:0046649 ! lymphocyte activation [Term] id: GO:0051250 name: negative regulation of lymphocyte activation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "down regulation of lymphocyte activation" EXACT [] synonym: "down-regulation of lymphocyte activation" EXACT [] synonym: "downregulation of lymphocyte activation" EXACT [] synonym: "inhibition of lymphocyte activation" NARROW [] is_a: GO:0002695 ! negative regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0046649 ! lymphocyte activation relationship: negatively_regulates GO:0046649 ! lymphocyte activation [Term] id: GO:0051251 name: positive regulation of lymphocyte activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." [GOC:ai] synonym: "activation of lymphocyte activation" NARROW [] synonym: "stimulation of lymphocyte activation" NARROW [] synonym: "up regulation of lymphocyte activation" EXACT [] synonym: "up-regulation of lymphocyte activation" EXACT [] synonym: "upregulation of lymphocyte activation" EXACT [] is_a: GO:0002696 ! positive regulation of leukocyte activation is_a: GO:0051249 ! regulation of lymphocyte activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0046649 ! lymphocyte activation relationship: positively_regulates GO:0046649 ! lymphocyte activation [Term] id: GO:0051252 name: regulation of RNA metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "regulation of RNA metabolism" EXACT [] is_a: GO:0019219 ! regulation of nucleobase-containing compound metabolic process is_a: GO:0060255 ! regulation of macromolecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016070 ! RNA metabolic process relationship: regulates GO:0016070 ! RNA metabolic process [Term] id: GO:0051253 name: negative regulation of RNA metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "down regulation of RNA metabolic process" EXACT [] synonym: "down-regulation of RNA metabolic process" EXACT [] synonym: "downregulation of RNA metabolic process" EXACT [] synonym: "inhibition of RNA metabolic process" NARROW [] synonym: "negative regulation of RNA metabolism" EXACT [] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0045934 ! negative regulation of nucleobase-containing compound metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016070 ! RNA metabolic process relationship: negatively_regulates GO:0016070 ! RNA metabolic process [Term] id: GO:0051254 name: positive regulation of RNA metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." [GOC:ai] synonym: "activation of RNA metabolic process" NARROW [] synonym: "positive regulation of RNA metabolism" EXACT [] synonym: "stimulation of RNA metabolic process" NARROW [] synonym: "up regulation of RNA metabolic process" EXACT [] synonym: "up-regulation of RNA metabolic process" EXACT [] synonym: "upregulation of RNA metabolic process" EXACT [] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0045935 ! positive regulation of nucleobase-containing compound metabolic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016070 ! RNA metabolic process relationship: positively_regulates GO:0016070 ! RNA metabolic process [Term] id: GO:0051258 name: protein polymerization namespace: biological_process def: "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." [GOC:ai] subset: goslim_pir synonym: "protein polymer biosynthesis" EXACT [] synonym: "protein polymer biosynthetic process" EXACT [] synonym: "protein polymer formation" EXACT [] is_a: GO:0065003 ! protein-containing complex assembly [Term] id: GO:0051261 name: protein depolymerization namespace: biological_process def: "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." [GOC:ai] subset: goslim_pir synonym: "protein polymer breakdown" EXACT [] synonym: "protein polymer catabolic process" EXACT [] synonym: "protein polymer catabolism" EXACT [] synonym: "protein polymer degradation" EXACT [] is_a: GO:0032984 ! protein-containing complex disassembly [Term] id: GO:0051276 name: chromosome organization namespace: biological_process alt_id: GO:0006323 alt_id: GO:0007001 alt_id: GO:0051277 def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_chembl subset: goslim_drosophila subset: goslim_pir synonym: "chromosome organisation" EXACT [] synonym: "chromosome organization and biogenesis" RELATED [GOC:mah] synonym: "DNA condensation" EXACT [] synonym: "DNA packaging" NARROW [] synonym: "maintenance of genome integrity" RELATED [] synonym: "nuclear genome maintenance" RELATED [] is_a: GO:0006996 ! organelle organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005694 ! chromosome relationship: results_in_organization_of GO:0005694 ! chromosome property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22811" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/4585" xsd:anyURI [Term] id: GO:0051301 name: cell division namespace: biological_process def: "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." [GOC:di, GOC:go_curators, GOC:pr] comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division. subset: goslim_chembl subset: goslim_drosophila subset: goslim_pir xref: Wikipedia:Cell_division is_a: GO:0009987 ! cellular process [Term] id: GO:0051302 name: regulation of cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." [GOC:go_curators] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051301 ! cell division relationship: regulates GO:0051301 ! cell division [Term] id: GO:0051303 name: establishment of chromosome localization namespace: biological_process def: "The directed movement of a chromosome to a specific location." [GOC:ai] synonym: "chromosome positioning" EXACT [] synonym: "establishment of chromosome localisation" EXACT [GOC:mah] is_a: GO:0050000 ! chromosome localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0005694 ! chromosome [Term] id: GO:0051321 name: meiotic cell cycle namespace: biological_process alt_id: GO:0007126 def: "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." [GOC:ai] comment: Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. subset: goslim_drosophila subset: goslim_yeast synonym: "meiosis" RELATED [] xref: Wikipedia:Meiosis is_a: GO:0007049 ! cell cycle is_a: GO:0022414 ! reproductive process intersection_of: GO:0007049 ! cell cycle intersection_of: has_part GO:0140013 ! meiotic nuclear division relationship: has_part GO:0140013 ! meiotic nuclear division relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0019953 ! sexual reproduction property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24599" xsd:anyURI [Term] id: GO:0051336 name: regulation of hydrolase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." [GOC:ai] subset: term_scheduled_for_obsoletion synonym: "hydrolase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016787 ! hydrolase activity relationship: regulates GO:0016787 ! hydrolase activity [Term] id: GO:0051338 name: regulation of transferase activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_do_not_manually_annotate subset: term_scheduled_for_obsoletion synonym: "transferase regulator" EXACT [] is_a: GO:0050790 ! regulation of catalytic activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016740 ! transferase activity relationship: regulates GO:0016740 ! transferase activity [Term] id: GO:0051345 name: positive regulation of hydrolase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] subset: term_scheduled_for_obsoletion synonym: "activation of hydrolase activity" NARROW [] synonym: "hydrolase activator" EXACT [] synonym: "stimulation of hydrolase activity" NARROW [] synonym: "up regulation of hydrolase activity" EXACT [] synonym: "up-regulation of hydrolase activity" EXACT [] synonym: "upregulation of hydrolase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016787 ! hydrolase activity relationship: positively_regulates GO:0016787 ! hydrolase activity [Term] id: GO:0051346 name: negative regulation of hydrolase activity namespace: biological_process def: "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." [GOC:ai] subset: term_scheduled_for_obsoletion synonym: "down regulation of hydrolase activity" EXACT [] synonym: "down-regulation of hydrolase activity" EXACT [] synonym: "downregulation of hydrolase activity" EXACT [] synonym: "hydrolase inhibitor" EXACT [] synonym: "inhibition of hydrolase activity" NARROW [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051336 ! regulation of hydrolase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016787 ! hydrolase activity relationship: negatively_regulates GO:0016787 ! hydrolase activity [Term] id: GO:0051347 name: positive regulation of transferase activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_do_not_manually_annotate subset: term_scheduled_for_obsoletion synonym: "activation of transferase activity" NARROW [] synonym: "stimulation of transferase activity" NARROW [] synonym: "transferase activator" EXACT [] synonym: "up regulation of transferase activity" EXACT [] synonym: "up-regulation of transferase activity" EXACT [] synonym: "upregulation of transferase activity" EXACT [] is_a: GO:0043085 ! positive regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0016740 ! transferase activity relationship: positively_regulates GO:0016740 ! transferase activity [Term] id: GO:0051348 name: negative regulation of transferase activity namespace: biological_process def: "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." [GOC:ai] comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. subset: gocheck_do_not_manually_annotate subset: term_scheduled_for_obsoletion synonym: "down regulation of transferase activity" EXACT [] synonym: "down-regulation of transferase activity" EXACT [] synonym: "downregulation of transferase activity" EXACT [] synonym: "inhibition of transferase activity" NARROW [] synonym: "transferase inhibitor" EXACT [] is_a: GO:0043086 ! negative regulation of catalytic activity is_a: GO:0051338 ! regulation of transferase activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0016740 ! transferase activity relationship: negatively_regulates GO:0016740 ! transferase activity [Term] id: GO:0051402 name: neuron apoptotic process namespace: biological_process def: "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." [CL:0000540, GOC:mtg_apoptosis] synonym: "apoptosis of neuronal cells" EXACT [] synonym: "apoptosis of neurons" EXACT [] synonym: "neuron apoptosis" NARROW [] synonym: "neuron programmed cell death by apoptosis" EXACT [] synonym: "neuronal cell apoptosis" EXACT [] synonym: "neuronal cell programmed cell death by apoptosis" EXACT [] synonym: "programmed cell death of neuronal cells by apoptosis" EXACT [] synonym: "programmed cell death of neurons by apoptosis" EXACT [] synonym: "programmed cell death, neuronal cells" EXACT [] synonym: "programmed cell death, neurons" EXACT [] is_a: GO:0006915 ! apoptotic process is_a: GO:0070997 ! neuron death intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000540 ! neuron [Term] id: GO:0051410 name: detoxification of nitrogen compound namespace: biological_process def: "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." [GOC:ai] synonym: "detoxification of nitrogenous compound" EXACT [] synonym: "nitric oxide (NO) detoxification" NARROW [] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: has_input CHEBI:51143 ! nitrogen molecular entity relationship: has_input CHEBI:51143 ! nitrogen molecular entity relationship: part_of GO:1901698 ! response to nitrogen compound [Term] id: GO:0051445 name: regulation of meiotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "meiotic cell cycle modulation" EXACT [] synonym: "meiotic cell cycle regulation" EXACT [] synonym: "meiotic cell cycle regulator" RELATED [] synonym: "modulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of meiotic cell cycle progression" EXACT [] synonym: "regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0051726 ! regulation of cell cycle is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051321 ! meiotic cell cycle relationship: regulates GO:0051321 ! meiotic cell cycle [Term] id: GO:0051446 name: positive regulation of meiotic cell cycle namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "activation of progression through meiotic cell cycle" NARROW [] synonym: "positive regulation of meiotic cell cycle progression" EXACT [] synonym: "positive regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of progression through meiotic cell cycle" NARROW [] synonym: "up regulation of progression through meiotic cell cycle" EXACT [] synonym: "up-regulation of progression through meiotic cell cycle" EXACT [] synonym: "upregulation of progression through meiotic cell cycle" EXACT [] is_a: GO:0045787 ! positive regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051321 ! meiotic cell cycle relationship: positively_regulates GO:0051321 ! meiotic cell cycle [Term] id: GO:0051447 name: negative regulation of meiotic cell cycle namespace: biological_process def: "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." [GOC:ai, GOC:dph, GOC:tb] synonym: "down regulation of progression through meiotic cell cycle" EXACT [] synonym: "down-regulation of progression through meiotic cell cycle" EXACT [] synonym: "downregulation of progression through meiotic cell cycle" EXACT [] synonym: "inhibition of progression through meiotic cell cycle" NARROW [] synonym: "negative regulation of meiotic cell cycle progression" EXACT [] synonym: "negative regulation of progression through meiotic cell cycle" EXACT [GOC:dph, GOC:tb] is_a: GO:0045786 ! negative regulation of cell cycle is_a: GO:0051445 ! regulation of meiotic cell cycle is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051321 ! meiotic cell cycle relationship: negatively_regulates GO:0051321 ! meiotic cell cycle [Term] id: GO:0051450 name: myoblast proliferation namespace: biological_process def: "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000056 ! myoblast relationship: acts_on_population_of CL:0000056 ! myoblast [Term] id: GO:0051451 name: myoblast migration namespace: biological_process def: "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." [CL:0000056, GOC:ai, GOC:mtg_muscle] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000056 ! myoblast relationship: results_in_movement_of CL:0000056 ! myoblast [Term] id: GO:0051469 name: vesicle fusion with vacuole namespace: biological_process alt_id: GO:0042146 def: "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." [GOC:ai] synonym: "heterotypic vacuole fusion (non-autophagic)" RELATED [] synonym: "heterotypic vacuole fusion, non-autophagic" RELATED [] is_a: GO:0006906 ! vesicle fusion is_a: GO:0097576 ! vacuole fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005773 ! vacuole intersection_of: results_in_fusion_of GO:0031982 ! vesicle relationship: results_in_fusion_of GO:0031982 ! vesicle [Term] id: GO:0051493 name: regulation of cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007010 ! cytoskeleton organization relationship: regulates GO:0007010 ! cytoskeleton organization [Term] id: GO:0051494 name: negative regulation of cytoskeleton organization namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "down regulation of cytoskeleton organization" EXACT [] synonym: "down-regulation of cytoskeleton organization" EXACT [] synonym: "downregulation of cytoskeleton organization" EXACT [] synonym: "inhibition of cytoskeleton organization" NARROW [] synonym: "negative regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "negative regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007010 ! cytoskeleton organization relationship: negatively_regulates GO:0007010 ! cytoskeleton organization [Term] id: GO:0051495 name: positive regulation of cytoskeleton organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:ai] synonym: "activation of cytoskeleton organization" NARROW [] synonym: "positive regulation of cytoskeleton organisation" EXACT [GOC:mah] synonym: "positive regulation of cytoskeleton organization and biogenesis" RELATED [GOC:mah] synonym: "stimulation of cytoskeleton organization" NARROW [] synonym: "up regulation of cytoskeleton organization" EXACT [] synonym: "up-regulation of cytoskeleton organization" EXACT [] synonym: "upregulation of cytoskeleton organization" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007010 ! cytoskeleton organization relationship: positively_regulates GO:0007010 ! cytoskeleton organization [Term] id: GO:0051588 name: regulation of neurotransmitter transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006836 ! neurotransmitter transport relationship: regulates GO:0006836 ! neurotransmitter transport [Term] id: GO:0051589 name: negative regulation of neurotransmitter transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of neurotransmitter transport" EXACT [] synonym: "down-regulation of neurotransmitter transport" EXACT [] synonym: "downregulation of neurotransmitter transport" EXACT [] synonym: "inhibition of neurotransmitter transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006836 ! neurotransmitter transport relationship: negatively_regulates GO:0006836 ! neurotransmitter transport [Term] id: GO:0051590 name: positive regulation of neurotransmitter transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of neurotransmitter transport" NARROW [] synonym: "stimulation of neurotransmitter transport" NARROW [] synonym: "up regulation of neurotransmitter transport" EXACT [] synonym: "up-regulation of neurotransmitter transport" EXACT [] synonym: "upregulation of neurotransmitter transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051588 ! regulation of neurotransmitter transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006836 ! neurotransmitter transport relationship: positively_regulates GO:0006836 ! neurotransmitter transport [Term] id: GO:0051602 name: response to electrical stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus." [GOC:ai] synonym: "response to electricity" RELATED [] is_a: GO:0009628 ! response to abiotic stimulus [Term] id: GO:0051606 name: detection of stimulus namespace: biological_process def: "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." [GOC:add, GOC:ai, GOC:dph, GOC:mah] subset: goslim_pir synonym: "perception of stimulus" RELATED [] synonym: "stimulus detection" EXACT [] synonym: "stimulus sensing" RELATED [] is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051620 name: norepinephrine uptake namespace: biological_process def: "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." [GOC:ai] synonym: "levarterenol reuptake" EXACT [] synonym: "levarterenol uptake" EXACT [] synonym: "noradrenaline reuptake" EXACT [] synonym: "noradrenaline uptake" EXACT [] synonym: "norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "norepinephrine reuptake" EXACT [] is_a: GO:0015874 ! norepinephrine transport is_a: GO:0090493 ! catecholamine uptake intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0051621 name: regulation of norepinephrine uptake namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." [GOC:ai] synonym: "regulation of levarterenol uptake" EXACT [] synonym: "regulation of noradrenaline uptake" EXACT [] synonym: "regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051620 ! norepinephrine uptake relationship: regulates GO:0051620 ! norepinephrine uptake [Term] id: GO:0051622 name: negative regulation of norepinephrine uptake namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "down regulation of norepinephrine uptake" EXACT [] synonym: "down-regulation of norepinephrine uptake" EXACT [] synonym: "downregulation of norepinephrine uptake" EXACT [] synonym: "negative regulation of levarterenol uptake" EXACT [] synonym: "negative regulation of noradrenaline uptake" EXACT [] synonym: "negative regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051620 ! norepinephrine uptake relationship: negatively_regulates GO:0051620 ! norepinephrine uptake [Term] id: GO:0051623 name: positive regulation of norepinephrine uptake namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." [GOC:ai] synonym: "activation of norepinephrine uptake" NARROW [] synonym: "positive regulation of levarterenol uptake" EXACT [] synonym: "positive regulation of noradrenaline uptake" EXACT [] synonym: "positive regulation of norepinephrine import" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of norepinephrine uptake" NARROW [] synonym: "up regulation of norepinephrine uptake" EXACT [] synonym: "up-regulation of norepinephrine uptake" EXACT [] synonym: "upregulation of norepinephrine uptake" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051621 ! regulation of norepinephrine uptake intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051620 ! norepinephrine uptake relationship: positively_regulates GO:0051620 ! norepinephrine uptake [Term] id: GO:0051630 name: acetylcholine uptake namespace: biological_process def: "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:ai] synonym: "acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0015870 ! acetylcholine transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:15355 ! acetylcholine intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure relationship: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0051631 name: regulation of acetylcholine uptake namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." [GOC:ai] synonym: "regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051630 ! acetylcholine uptake relationship: regulates GO:0051630 ! acetylcholine uptake [Term] id: GO:0051632 name: negative regulation of acetylcholine uptake namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "down regulation of acetylcholine uptake" EXACT [] synonym: "down-regulation of acetylcholine uptake" EXACT [] synonym: "downregulation of acetylcholine uptake" EXACT [] synonym: "negative regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051953 ! negative regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051630 ! acetylcholine uptake relationship: negatively_regulates GO:0051630 ! acetylcholine uptake [Term] id: GO:0051633 name: positive regulation of acetylcholine uptake namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." [GOC:ai] synonym: "activation of acetylcholine uptake" NARROW [] synonym: "positive regulation of acetylcholine import" EXACT [GOC:dph, GOC:tb] synonym: "stimulation of acetylcholine uptake" NARROW [] synonym: "up regulation of acetylcholine uptake" EXACT [] synonym: "up-regulation of acetylcholine uptake" EXACT [] synonym: "upregulation of acetylcholine uptake" EXACT [] is_a: GO:0051631 ! regulation of acetylcholine uptake is_a: GO:0051954 ! positive regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051630 ! acetylcholine uptake relationship: positively_regulates GO:0051630 ! acetylcholine uptake [Term] id: GO:0051640 name: organelle localization namespace: biological_process def: "Any process in which an organelle is transported to, and/or maintained in, a specific location." [GOC:ai] subset: goslim_pir synonym: "establishment and maintenance of organelle localization" EXACT [] synonym: "organelle localisation" EXACT [GOC:mah] is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0043226 ! organelle relationship: has_primary_input GO:0043226 ! organelle relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19809" xsd:anyURI [Term] id: GO:0051641 name: cellular localization namespace: biological_process alt_id: GO:1902580 def: "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." [GOC:tb, GOC:vw] subset: goslim_pir synonym: "cellular localisation" EXACT [GOC:mah] synonym: "establishment and maintenance of cellular localization" EXACT [] synonym: "establishment and maintenance of localization in cell or cell membrane" EXACT [] synonym: "intracellular localization" NARROW [] synonym: "localization within cell" NARROW [] synonym: "single organism cellular localization" EXACT [GOC:TermGenie] synonym: "single-organism cellular localization" RELATED [] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization created_by: jl creation_date: 2013-12-18T14:04:32Z [Term] id: GO:0051645 name: Golgi localization namespace: biological_process def: "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "establishment and maintenance of Golgi localization" EXACT [] synonym: "Golgi apparatus localization" EXACT [] synonym: "Golgi body localization" EXACT [] synonym: "Golgi localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005794 ! Golgi apparatus relationship: has_primary_input GO:0005794 ! Golgi apparatus [Term] id: GO:0051647 name: nucleus localization namespace: biological_process def: "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "cell nucleus localization" EXACT [] synonym: "establishment and maintenance of nucleus localization" EXACT [] synonym: "localization of nucleus" EXACT [] synonym: "nucleus localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005634 ! nucleus relationship: has_primary_input GO:0005634 ! nucleus [Term] id: GO:0051648 name: vesicle localization namespace: biological_process def: "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cytoplasmic vesicle localization" EXACT [] synonym: "establishment and maintenance of vesicle localization" EXACT [] synonym: "vesicle localisation" EXACT [GOC:mah] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0031982 ! vesicle relationship: has_primary_input GO:0031982 ! vesicle [Term] id: GO:0051649 name: establishment of localization in cell namespace: biological_process def: "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." [GOC:ai, GOC:dos, GOC:dph, GOC:tb] synonym: "establishment of cellular localization" RELATED [GOC:dph, GOC:tb] synonym: "establishment of intracellular localization" NARROW [] synonym: "establishment of localisation in cell" EXACT [GOC:mah] synonym: "establishment of localization within cell" NARROW [] synonym: "positioning within cell" NARROW [] is_a: GO:0051234 ! establishment of localization intersection_of: GO:0051234 ! establishment of localization intersection_of: occurs_in CL:0000000 ! cell relationship: in_taxon NCBITaxon:131567 {all_only="true"} ! cellular organisms relationship: occurs_in CL:0000000 ! cell relationship: only_in_taxon NCBITaxon:131567 ! cellular organisms relationship: part_of GO:0051641 ! cellular localization [Term] id: GO:0051650 name: establishment of vesicle localization namespace: biological_process def: "The directed movement of a vesicle to a specific location." [GOC:ai] synonym: "establishment of vesicle localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0031982 ! vesicle [Term] id: GO:0051656 name: establishment of organelle localization namespace: biological_process def: "The directed movement of an organelle to a specific location." [GOC:ai] synonym: "establishment of organelle localisation" EXACT [GOC:mah] is_a: GO:0051234 ! establishment of localization is_a: GO:0051640 ! organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0043226 ! organelle [Term] id: GO:0051668 name: localization within membrane namespace: biological_process def: "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." [GOC:ai] synonym: "establishment and maintenance of localization in membrane" EXACT [] synonym: "establishment and maintenance of position in membrane" EXACT [] synonym: "localisation within membrane" EXACT [GOC:mah] synonym: "localization to membrane" EXACT [] synonym: "positioning within membrane" NARROW [] is_a: GO:0051641 ! cellular localization intersection_of: GO:0051179 ! localization intersection_of: has_target_end_location GO:0016020 ! membrane relationship: has_target_end_location GO:0016020 ! membrane [Term] id: GO:0051674 name: localization of cell namespace: biological_process def: "Any process in which a cell is transported to, and/or maintained in, a specific location." [GOC:ai] synonym: "cell localization" EXACT [] synonym: "establishment and maintenance of cell localization" EXACT [] synonym: "establishment and maintenance of localization of cell" EXACT [] synonym: "localisation of cell" EXACT [GOC:mah] is_a: GO:0009987 ! cellular process is_a: GO:0051179 ! localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input CL:0000000 ! cell relationship: has_primary_input CL:0000000 ! cell [Term] id: GO:0051683 name: establishment of Golgi localization namespace: biological_process def: "The directed movement of the Golgi to a specific location." [GOC:ai] synonym: "establishment of Golgi apparatus localization" EXACT [] synonym: "establishment of Golgi body localization" EXACT [] synonym: "establishment of Golgi localisation" EXACT [GOC:mah] is_a: GO:0051645 ! Golgi localization is_a: GO:0051649 ! establishment of localization in cell is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0051234 ! establishment of localization intersection_of: has_primary_input GO:0005794 ! Golgi apparatus [Term] id: GO:0051707 name: response to other organism namespace: biological_process alt_id: GO:0009613 alt_id: GO:0042828 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." [GOC:ai] is_a: GO:0043207 ! response to external biotic stimulus is_a: GO:0044419 ! biological process involved in interspecies interaction between organisms intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input NCBITaxon_Union:0000030 relationship: has_input NCBITaxon_Union:0000030 [Term] id: GO:0051716 name: cellular response to stimulus namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." [GOC:bf, GOC:jl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0009987 ! cellular process is_a: GO:0050896 ! response to stimulus [Term] id: GO:0051726 name: regulation of cell cycle namespace: biological_process alt_id: GO:0000074 alt_id: GO:0007050 alt_id: GO:0071156 alt_id: GO:0071157 alt_id: GO:0071158 alt_id: GO:0071850 def: "Any process that modulates the rate or extent of progression through the cell cycle." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_yeast synonym: "arrest of mitotic cell cycle progression" NARROW [GOC:mah] synonym: "cell cycle arrest" NARROW [] synonym: "cell cycle modulation" EXACT [] synonym: "cell cycle regulation" EXACT [] synonym: "cell cycle regulator" RELATED [] synonym: "control of cell cycle progression" EXACT [] synonym: "mitotic cell cycle arrest" NARROW [] synonym: "modulation of cell cycle progression" EXACT [] synonym: "negative regulation of cell cycle arrest" NARROW [] synonym: "positive regulation of cell cycle arrest" NARROW [] synonym: "regulation of cell cycle arrest" NARROW [] synonym: "regulation of cell cycle progression" EXACT [] synonym: "regulation of progression through cell cycle" EXACT [] synonym: "tumor suppressor" RELATED [] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007049 ! cell cycle relationship: regulates GO:0007049 ! cell cycle [Term] id: GO:0051781 name: positive regulation of cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell division." [GOC:ai] synonym: "activation of cell division" NARROW [] synonym: "stimulation of cell division" NARROW [] synonym: "up regulation of cell division" EXACT [] synonym: "up-regulation of cell division" EXACT [] synonym: "upregulation of cell division" EXACT [] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051301 ! cell division relationship: positively_regulates GO:0051301 ! cell division [Term] id: GO:0051782 name: negative regulation of cell division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." [GOC:ai] synonym: "down regulation of cell division" EXACT [] synonym: "down-regulation of cell division" EXACT [] synonym: "downregulation of cell division" EXACT [] synonym: "inhibition of cell division" NARROW [] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051301 ! cell division relationship: negatively_regulates GO:0051301 ! cell division [Term] id: GO:0051783 name: regulation of nuclear division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000280 ! nuclear division relationship: regulates GO:0000280 ! nuclear division [Term] id: GO:0051784 name: negative regulation of nuclear division namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "down regulation of nuclear division" EXACT [] synonym: "down-regulation of nuclear division" EXACT [] synonym: "downregulation of nuclear division" EXACT [] synonym: "inhibition of nuclear division" NARROW [] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0000280 ! nuclear division relationship: negatively_regulates GO:0000280 ! nuclear division [Term] id: GO:0051785 name: positive regulation of nuclear division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." [GOC:ai] synonym: "activation of nuclear division" NARROW [] synonym: "stimulation of nuclear division" NARROW [] synonym: "up regulation of nuclear division" EXACT [] synonym: "up-regulation of nuclear division" EXACT [] synonym: "upregulation of nuclear division" EXACT [] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0051783 ! regulation of nuclear division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000280 ! nuclear division relationship: positively_regulates GO:0000280 ! nuclear division [Term] id: GO:0051875 name: pigment granule localization namespace: biological_process def: "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." [GOC:ai] synonym: "pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051648 ! vesicle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0048770 ! pigment granule relationship: has_primary_input GO:0048770 ! pigment granule relationship: part_of GO:0033059 ! cellular pigmentation [Term] id: GO:0051890 name: regulation of cardioblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] is_a: GO:1905207 ! regulation of cardiocyte differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010002 ! cardioblast differentiation relationship: regulates GO:0010002 ! cardioblast differentiation [Term] id: GO:0051891 name: positive regulation of cardioblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "activation of cardioblast differentiation" NARROW [] synonym: "stimulation of cardioblast differentiation" NARROW [] synonym: "up regulation of cardioblast differentiation" EXACT [] synonym: "up-regulation of cardioblast differentiation" EXACT [] synonym: "upregulation of cardioblast differentiation" EXACT [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010002 ! cardioblast differentiation relationship: positively_regulates GO:0010002 ! cardioblast differentiation [Term] id: GO:0051892 name: negative regulation of cardioblast differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." [GOC:ai] synonym: "down regulation of cardioblast differentiation" EXACT [] synonym: "down-regulation of cardioblast differentiation" EXACT [] synonym: "downregulation of cardioblast differentiation" EXACT [] synonym: "inhibition of cardioblast differentiation" NARROW [] is_a: GO:0051890 ! regulation of cardioblast differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010002 ! cardioblast differentiation relationship: negatively_regulates GO:0010002 ! cardioblast differentiation [Term] id: GO:0051904 name: pigment granule transport namespace: biological_process def: "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "pigment granule translocation" EXACT [] is_a: GO:0006810 ! transport is_a: GO:0051875 ! pigment granule localization is_a: GO:0051905 ! establishment of pigment granule localization intersection_of: GO:0006810 ! transport intersection_of: has_primary_input GO:0048770 ! pigment granule [Term] id: GO:0051905 name: establishment of pigment granule localization namespace: biological_process def: "The directed movement of a pigment granule to a specific location." [GOC:ai] synonym: "establishment of pigment granule localisation" EXACT [GOC:mah] is_a: GO:0051650 ! establishment of vesicle localization relationship: part_of GO:0051875 ! pigment granule localization [Term] id: GO:0051930 name: regulation of sensory perception of pain namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0051931 ! regulation of sensory perception intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019233 ! sensory perception of pain relationship: regulates GO:0019233 ! sensory perception of pain [Term] id: GO:0051931 name: regulation of sensory perception namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." [GOC:ai] is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007600 ! sensory perception relationship: regulates GO:0007600 ! sensory perception [Term] id: GO:0051937 name: catecholamine transport namespace: biological_process def: "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." [GOC:ai, ISBN:0198506732] is_a: GO:0015844 ! monoamine transport is_a: GO:0015850 ! organic hydroxy compound transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33567 ! catecholamine relationship: has_primary_input CHEBI:33567 ! catecholamine [Term] id: GO:0051952 name: regulation of amine transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015837 ! amine transport relationship: regulates GO:0015837 ! amine transport [Term] id: GO:0051953 name: negative regulation of amine transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amine transport" EXACT [] synonym: "down-regulation of amine transport" EXACT [] synonym: "downregulation of amine transport" EXACT [] synonym: "inhibition of amine transport" NARROW [] is_a: GO:0051051 ! negative regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015837 ! amine transport relationship: negatively_regulates GO:0015837 ! amine transport [Term] id: GO:0051954 name: positive regulation of amine transport namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of amine transport" NARROW [] synonym: "stimulation of amine transport" NARROW [] synonym: "up regulation of amine transport" EXACT [] synonym: "up-regulation of amine transport" EXACT [] synonym: "upregulation of amine transport" EXACT [] is_a: GO:0051050 ! positive regulation of transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015837 ! amine transport relationship: positively_regulates GO:0015837 ! amine transport [Term] id: GO:0051955 name: regulation of amino acid transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] is_a: GO:0032890 ! regulation of organic acid transport is_a: GO:0051952 ! regulation of amine transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006865 ! amino acid transport relationship: regulates GO:0006865 ! amino acid transport [Term] id: GO:0051956 name: negative regulation of amino acid transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "down regulation of amino acid transport" EXACT [] synonym: "down-regulation of amino acid transport" EXACT [] synonym: "downregulation of amino acid transport" EXACT [] synonym: "inhibition of amino acid transport" NARROW [] synonym: "negative regulation of amino acid transmembrane transport" EXACT [GOC:mah] is_a: GO:0032891 ! negative regulation of organic acid transport is_a: GO:0051953 ! negative regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006865 ! amino acid transport relationship: negatively_regulates GO:0006865 ! amino acid transport [Term] id: GO:0051957 name: positive regulation of amino acid transport namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:ai] synonym: "activation of amino acid transport" NARROW [] synonym: "positive regulation of amino acid transmembrane transport" EXACT [GOC:mah] synonym: "stimulation of amino acid transport" NARROW [] synonym: "up regulation of amino acid transport" EXACT [] synonym: "up-regulation of amino acid transport" EXACT [] synonym: "upregulation of amino acid transport" EXACT [] is_a: GO:0032892 ! positive regulation of organic acid transport is_a: GO:0051954 ! positive regulation of amine transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006865 ! amino acid transport relationship: positively_regulates GO:0006865 ! amino acid transport [Term] id: GO:0051960 name: regulation of nervous system development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007399 ! nervous system development relationship: regulates GO:0007399 ! nervous system development [Term] id: GO:0051961 name: negative regulation of nervous system development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "down regulation of nervous system development" EXACT [] synonym: "down-regulation of nervous system development" EXACT [] synonym: "downregulation of nervous system development" EXACT [] synonym: "inhibition of nervous system development" NARROW [] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007399 ! nervous system development relationship: negatively_regulates GO:0007399 ! nervous system development [Term] id: GO:0051962 name: positive regulation of nervous system development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." [GOC:ai] synonym: "activation of nervous system development" NARROW [] synonym: "stimulation of nervous system development" NARROW [] synonym: "up regulation of nervous system development" EXACT [] synonym: "up-regulation of nervous system development" EXACT [] synonym: "upregulation of nervous system development" EXACT [] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0051960 ! regulation of nervous system development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007399 ! nervous system development relationship: positively_regulates GO:0007399 ! nervous system development [Term] id: GO:0051963 name: regulation of synapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] subset: goslim_synapse synonym: "regulation of synapse biogenesis" EXACT [] synonym: "regulation of synaptogenesis" EXACT [] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007416 ! synapse assembly relationship: regulates GO:0007416 ! synapse assembly [Term] id: GO:0051964 name: negative regulation of synapse assembly namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "down regulation of synapse assembly" EXACT [] synonym: "down-regulation of synapse assembly" EXACT [] synonym: "downregulation of synapse assembly" EXACT [] synonym: "inhibition of synapse assembly" NARROW [] synonym: "negative regulation of synapse biogenesis" EXACT [] synonym: "negative regulation of synaptogenesis" EXACT [] is_a: GO:0051961 ! negative regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901889 ! negative regulation of cell junction assembly is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007416 ! synapse assembly relationship: negatively_regulates GO:0007416 ! synapse assembly [Term] id: GO:0051965 name: positive regulation of synapse assembly namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." [GOC:ai, GOC:pr] synonym: "activation of synapse assembly" NARROW [] synonym: "positive regulation of synapse biogenesis" EXACT [] synonym: "positive regulation of synaptogenesis" EXACT [] synonym: "stimulation of synapse assembly" NARROW [] synonym: "up regulation of synapse assembly" EXACT [] synonym: "up-regulation of synapse assembly" EXACT [] synonym: "upregulation of synapse assembly" EXACT [] is_a: GO:0051962 ! positive regulation of nervous system development is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:1901890 ! positive regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007416 ! synapse assembly relationship: positively_regulates GO:0007416 ! synapse assembly [Term] id: GO:0051969 name: regulation of transmission of nerve impulse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0031644 ! regulation of nervous system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019226 ! transmission of nerve impulse relationship: regulates GO:0019226 ! transmission of nerve impulse [Term] id: GO:0051970 name: negative regulation of transmission of nerve impulse namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "down regulation of transmission of nerve impulse" EXACT [] synonym: "down-regulation of transmission of nerve impulse" EXACT [] synonym: "downregulation of transmission of nerve impulse" EXACT [] synonym: "inhibition of transmission of nerve impulse" NARROW [] synonym: "negative regulation of conduction of nerve impulse" EXACT [GOC:dph] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019226 ! transmission of nerve impulse relationship: negatively_regulates GO:0019226 ! transmission of nerve impulse [Term] id: GO:0051971 name: positive regulation of transmission of nerve impulse namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." [GOC:ai] synonym: "activation of transmission of nerve impulse" NARROW [] synonym: "positive regulation of conduction of nerve impulse" EXACT [GOC:dph] synonym: "stimulation of transmission of nerve impulse" NARROW [] synonym: "up regulation of transmission of nerve impulse" EXACT [] synonym: "up-regulation of transmission of nerve impulse" EXACT [] synonym: "upregulation of transmission of nerve impulse" EXACT [] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051969 ! regulation of transmission of nerve impulse intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019226 ! transmission of nerve impulse relationship: positively_regulates GO:0019226 ! transmission of nerve impulse [Term] id: GO:0051983 name: regulation of chromosome segregation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007059 ! chromosome segregation relationship: regulates GO:0007059 ! chromosome segregation [Term] id: GO:0051984 name: positive regulation of chromosome segregation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "activation of chromosome segregation" NARROW [] synonym: "stimulation of chromosome segregation" NARROW [] synonym: "up regulation of chromosome segregation" EXACT [] synonym: "up-regulation of chromosome segregation" EXACT [] synonym: "upregulation of chromosome segregation" EXACT [] is_a: GO:0051983 ! regulation of chromosome segregation is_a: GO:0090068 ! positive regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007059 ! chromosome segregation relationship: positively_regulates GO:0007059 ! chromosome segregation [Term] id: GO:0051985 name: negative regulation of chromosome segregation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." [GOC:ai] synonym: "down regulation of chromosome segregation" EXACT [] synonym: "down-regulation of chromosome segregation" EXACT [] synonym: "downregulation of chromosome segregation" EXACT [] synonym: "inhibition of chromosome segregation" NARROW [] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051983 ! regulation of chromosome segregation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007059 ! chromosome segregation relationship: negatively_regulates GO:0007059 ! chromosome segregation [Term] id: GO:0055001 name: muscle cell development namespace: biological_process alt_id: GO:0048747 def: "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." [CL:0000187, GOC:devbiol] synonym: "muscle fiber development" EXACT [] synonym: "muscle fibre development" EXACT [] synonym: "myofiber development" EXACT [] synonym: "myofibre development" EXACT [] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000187 ! muscle cell relationship: part_of GO:0042692 ! muscle cell differentiation relationship: results_in_development_of CL:0000187 ! muscle cell [Term] id: GO:0055002 name: striated muscle cell development namespace: biological_process def: "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." [CL:0000737, GOC:devbiol] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000737 ! striated muscle cell relationship: part_of GO:0051146 ! striated muscle cell differentiation relationship: results_in_development_of CL:0000737 ! striated muscle cell [Term] id: GO:0055003 name: cardiac myofibril assembly namespace: biological_process def: "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:devbiol] synonym: "cardiac myofibril development" EXACT [] synonym: "cardiac myofibril morphogenesis" EXACT [] synonym: "heart myofibril assembly" RELATED [] is_a: GO:0030239 ! myofibril assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0097512 ! cardiac myofibril relationship: part_of GO:0055013 ! cardiac muscle cell development relationship: results_in_assembly_of GO:0097512 ! cardiac myofibril [Term] id: GO:0055006 name: cardiac cell development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." [GOC:devbiol] synonym: "cardiocyte development" EXACT [GOC:dph] synonym: "heart cell development" RELATED [] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0002494 ! cardiocyte relationship: part_of GO:0035051 ! cardiocyte differentiation relationship: results_in_development_of CL:0002494 ! cardiocyte [Term] id: GO:0055007 name: cardiac muscle cell differentiation namespace: biological_process def: "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiomyocyte differentiation" EXACT [] synonym: "heart muscle cell differentiation" RELATED [] is_a: GO:0035051 ! cardiocyte differentiation is_a: GO:0051146 ! striated muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000746 ! cardiac muscle cell relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: results_in_acquisition_of_features_of CL:0000746 ! cardiac muscle cell [Term] id: GO:0055008 name: cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." [GOC:devbiol] synonym: "heart muscle morphogenesis" EXACT [] synonym: "myocardium morphogenesis" BROAD [GOC:mtg_heart] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: results_in_morphogenesis_of UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0055009 name: atrial cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." [GOC:devbiol] synonym: "atrial heart muscle morphogenesis" EXACT [] synonym: "atrial myocardium morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac atrium muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004490 ! cardiac muscle tissue of atrium relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: part_of GO:0003228 ! atrial cardiac muscle tissue development relationship: results_in_morphogenesis_of UBERON:0004490 ! cardiac muscle tissue of atrium [Term] id: GO:0055010 name: ventricular cardiac muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." [GOC:devbiol] synonym: "cardiac ventricle muscle morphogenesis" EXACT [] synonym: "ventricular heart muscle morphogenesis" EXACT [] is_a: GO:0055008 ! cardiac muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: part_of GO:0003208 ! cardiac ventricle morphogenesis relationship: part_of GO:0003229 ! ventricular cardiac muscle tissue development relationship: results_in_morphogenesis_of UBERON:0018649 ! cardiac muscle tissue of ventricle [Term] id: GO:0055013 name: cardiac muscle cell development namespace: biological_process alt_id: GO:0048739 def: "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." [GOC:devbiol, GOC:mtg_heart] synonym: "cardiac muscle fiber development" EXACT [] synonym: "cardiac muscle fibre development" EXACT [] synonym: "cardiomyocyte cell development" EXACT [GOC:mtg_muscle] synonym: "heart muscle cell development" EXACT [] synonym: "heart muscle fiber development" RELATED [] is_a: GO:0055002 ! striated muscle cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000746 ! cardiac muscle cell relationship: part_of GO:0055007 ! cardiac muscle cell differentiation relationship: results_in_development_of CL:0000746 ! cardiac muscle cell [Term] id: GO:0055017 name: cardiac muscle tissue growth namespace: biological_process def: "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." [GOC:devbiol] synonym: "heart muscle growth" EXACT [] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0048738 ! cardiac muscle tissue development relationship: part_of GO:0060419 ! heart growth relationship: results_in_growth_of UBERON:0001133 ! cardiac muscle tissue [Term] id: GO:0055018 name: regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "regulation of cardiac muscle fibre development" EXACT [] synonym: "regulation of heart muscle fiber development" EXACT [] is_a: GO:0060284 ! regulation of cell development is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055013 ! cardiac muscle cell development relationship: regulates GO:0055013 ! cardiac muscle cell development [Term] id: GO:0055019 name: negative regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "down regulation of cardiac muscle fiber development" EXACT [] synonym: "down-regulation of cardiac muscle fiber development" EXACT [] synonym: "downregulation of cardiac muscle fiber development" EXACT [] synonym: "inhibition of cardiac muscle fiber development" NARROW [] synonym: "negative regulation of cardiac muscle fibre development" EXACT [] synonym: "negative regulation of heart muscle fiber development" RELATED [] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055018 ! regulation of cardiac muscle fiber development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055013 ! cardiac muscle cell development relationship: negatively_regulates GO:0055013 ! cardiac muscle cell development [Term] id: GO:0055020 name: positive regulation of cardiac muscle fiber development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." [GOC:vk] synonym: "activation of cardiac muscle fiber development" NARROW [] synonym: "positive regulation of cardiac muscle fibre development" EXACT [] synonym: "positive regulation of heart muscle fiber development" EXACT [] synonym: "stimulation of cardiac muscle fiber development" NARROW [] synonym: "up regulation of cardiac muscle fiber development" EXACT [] synonym: "up-regulation of cardiac muscle fiber development" EXACT [] synonym: "upregulation of cardiac muscle fiber development" EXACT [] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0055018 ! regulation of cardiac muscle fiber development is_a: GO:2000727 ! positive regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055013 ! cardiac muscle cell development relationship: positively_regulates GO:0055013 ! cardiac muscle cell development [Term] id: GO:0055021 name: regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle growth." [GOC:vk] is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055017 ! cardiac muscle tissue growth relationship: regulates GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0055022 name: negative regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "down regulation of cardiac muscle growth" EXACT [] synonym: "down-regulation of cardiac muscle growth" EXACT [] synonym: "downregulation of cardiac muscle growth" EXACT [] synonym: "inhibition of cardiac muscle growth" NARROW [] synonym: "negative regulation of heart muscle growth" RELATED [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0061117 ! negative regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055017 ! cardiac muscle tissue growth relationship: negatively_regulates GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0055023 name: positive regulation of cardiac muscle tissue growth namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." [GOC:vk] synonym: "activation of cardiac muscle growth" NARROW [] synonym: "positive regulation of heart muscle growth" EXACT [] synonym: "stimulation of cardiac muscle growth" NARROW [] synonym: "up regulation of cardiac muscle growth" EXACT [] synonym: "up-regulation of cardiac muscle growth" EXACT [] synonym: "upregulation of cardiac muscle growth" EXACT [] is_a: GO:0055021 ! regulation of cardiac muscle tissue growth is_a: GO:0060421 ! positive regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055017 ! cardiac muscle tissue growth relationship: positively_regulates GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0055024 name: regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "regulation of heart muscle development" EXACT [] is_a: GO:0016202 ! regulation of striated muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048738 ! cardiac muscle tissue development relationship: regulates GO:0048738 ! cardiac muscle tissue development [Term] id: GO:0055025 name: positive regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "activation of cardiac muscle development" NARROW [] synonym: "positive regulation of heart muscle development" EXACT [] synonym: "stimulation of cardiac muscle development" NARROW [] synonym: "up regulation of cardiac muscle development" EXACT [] synonym: "up-regulation of cardiac muscle development" EXACT [] synonym: "upregulation of cardiac muscle development" EXACT [] is_a: GO:0045844 ! positive regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048738 ! cardiac muscle tissue development relationship: positively_regulates GO:0048738 ! cardiac muscle tissue development [Term] id: GO:0055026 name: negative regulation of cardiac muscle tissue development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." [GOC:vk] synonym: "down regulation of cardiac muscle development" EXACT [] synonym: "down-regulation of cardiac muscle development" EXACT [] synonym: "downregulation of cardiac muscle development" EXACT [] synonym: "inhibition of cardiac muscle development" NARROW [] synonym: "negative regulation of heart muscle development" EXACT [] is_a: GO:0045843 ! negative regulation of striated muscle tissue development is_a: GO:0055024 ! regulation of cardiac muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048738 ! cardiac muscle tissue development relationship: negatively_regulates GO:0048738 ! cardiac muscle tissue development [Term] id: GO:0055057 name: neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." [PMID:11163136, PMID:11250167] synonym: "neuroblast cell division" EXACT [] is_a: GO:0051301 ! cell division intersection_of: GO:0051301 ! cell division intersection_of: has_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: has_input CL:0000031 ! neuroblast (sensu Vertebrata) relationship: part_of GO:0007405 ! neuroblast proliferation [Term] id: GO:0055059 name: asymmetric neuroblast division namespace: biological_process def: "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." [GOC:dph] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0045165 ! cell fate commitment is_a: GO:0055057 ! neuroblast division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_input CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: GO:0055085 name: transmembrane transport namespace: biological_process alt_id: GO:0090662 def: "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." [GOC:dph, GOC:jid] comment: Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes. subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_yeast synonym: "ATP hydrolysis coupled transmembrane transport" NARROW [] synonym: "membrane transport" EXACT [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: results_in_transport_across GO:0016020 ! membrane created_by: tb creation_date: 2015-10-21T13:22:47Z [Term] id: GO:0055086 name: nucleobase-containing small molecule metabolic process namespace: biological_process def: "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." [GOC:vw] subset: goslim_drosophila subset: goslim_generic subset: goslim_pombe subset: goslim_yeast subset: prokaryote_subset synonym: "nucleobase, nucleoside and nucleotide metabolic process" RELATED [] synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT [] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0044281 ! small molecule metabolic process [Term] id: GO:0055107 name: Golgi to secretory granule transport namespace: biological_process def: "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." [GOC:curators] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0030141 ! secretory granule intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: occurs_in GO:0005737 ! cytoplasm relationship: has_target_end_location GO:0030141 ! secretory granule relationship: has_target_start_location GO:0005794 ! Golgi apparatus relationship: occurs_in GO:0005737 ! cytoplasm [Term] id: GO:0055108 name: Golgi to transport vesicle transport namespace: biological_process def: "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." [GOC:jid] is_a: GO:0046907 ! intracellular transport intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0030133 ! transport vesicle intersection_of: has_target_start_location GO:0005794 ! Golgi apparatus intersection_of: occurs_in GO:0005737 ! cytoplasm relationship: has_target_end_location GO:0030133 ! transport vesicle relationship: has_target_start_location GO:0005794 ! Golgi apparatus relationship: occurs_in GO:0005737 ! cytoplasm relationship: part_of GO:0048193 ! Golgi vesicle transport [Term] id: GO:0055111 name: ingression involved in gastrulation with mouth forming second namespace: biological_process def: "The migration of individual cells into the embryo involved in deuterostomic gastrulation." [ISBN:0878932437] is_a: GO:0042074 ! cell migration involved in gastrulation intersection_of: GO:0001667 ! ameboidal-type cell migration intersection_of: part_of GO:0001702 ! gastrulation with mouth forming second relationship: part_of GO:0001702 ! gastrulation with mouth forming second [Term] id: GO:0055117 name: regulation of cardiac muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0006942 ! regulation of striated muscle contraction is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060048 ! cardiac muscle contraction relationship: regulates GO:0060048 ! cardiac muscle contraction [Term] id: GO:0055118 name: negative regulation of cardiac muscle contraction namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." [GOC:ecd] is_a: GO:0045822 ! negative regulation of heart contraction is_a: GO:0045988 ! negative regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060048 ! cardiac muscle contraction relationship: negatively_regulates GO:0060048 ! cardiac muscle contraction [Term] id: GO:0055123 name: digestive system development namespace: biological_process def: "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:jid] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001007 ! digestive system relationship: results_in_development_of UBERON:0001007 ! digestive system [Term] id: GO:0055127 name: vibrational conductance of sound to the inner ear namespace: biological_process def: "The transmission of vibrations via ossicles to the inner ear." [GOC:mh] is_a: GO:0032501 ! multicellular organismal process relationship: part_of GO:0007605 ! sensory perception of sound created_by: jid creation_date: 2009-10-13T10:59:39Z [Term] id: GO:0060008 name: Sertoli cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000216 ! Sertoli cell relationship: part_of GO:0008584 ! male gonad development relationship: results_in_acquisition_of_features_of CL:0000216 ! Sertoli cell [Term] id: GO:0060009 name: Sertoli cell development namespace: biological_process def: "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." [GOC:dph] is_a: GO:0002064 ! epithelial cell development is_a: GO:0003006 ! developmental process involved in reproduction intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000216 ! Sertoli cell relationship: part_of GO:0060008 ! Sertoli cell differentiation relationship: results_in_development_of CL:0000216 ! Sertoli cell [Term] id: GO:0060011 name: Sertoli cell proliferation namespace: biological_process def: "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." [GOC:dph] is_a: GO:0022414 ! reproductive process is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000216 ! Sertoli cell relationship: acts_on_population_of CL:0000216 ! Sertoli cell relationship: part_of GO:0008584 ! male gonad development [Term] id: GO:0060021 name: roof of mouth development namespace: biological_process def: "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities." [GOC:dph, ISBN:0721662544] synonym: "palatum development" EXACT [ISBN:0721662544] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0007375 ! roof of mouth relationship: results_in_development_of UBERON:0007375 ! roof of mouth [Term] id: GO:0060022 name: hard palate development namespace: biological_process def: "The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes." [GOC:dph, ISBN:0721662544] synonym: "palatum durum development" EXACT [ISBN:0721662544] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003216 ! hard palate relationship: part_of GO:0062009 ! secondary palate development relationship: results_in_development_of UBERON:0003216 ! hard palate [Term] id: GO:0060037 name: pharyngeal system development namespace: biological_process def: "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0008814 ! pharyngeal arch system relationship: part_of GO:0043009 ! chordate embryonic development relationship: results_in_development_of UBERON:0008814 ! pharyngeal arch system [Term] id: GO:0060038 name: cardiac muscle cell proliferation namespace: biological_process def: "The expansion of a cardiac muscle cell population by cell division." [GOC:dph, GOC:rph, PMID:11161571] synonym: "cardiac myocyte proliferation" EXACT [] synonym: "cardiomyocyte proliferation" RELATED [GOC:dph, PMID:10074473] synonym: "heart muscle cell proliferation" EXACT [] is_a: GO:0014855 ! striated muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000746 ! cardiac muscle cell relationship: acts_on_population_of CL:0000746 ! cardiac muscle cell relationship: part_of GO:0055017 ! cardiac muscle tissue growth [Term] id: GO:0060039 name: pericardium development namespace: biological_process def: "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." [GOC:dph, GOC:rph, PMID:15138308, PMID:16376438] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002407 ! pericardium relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0002407 ! pericardium [Term] id: GO:0060041 name: retina development in camera-type eye namespace: biological_process alt_id: GO:0002073 def: "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [GOC:bf, GOC:dph, ISBN:0815340729] synonym: "retina development in camera-style eye" EXACT [] synonym: "retinal development" RELATED [GOC:dph, GOC:tb] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: part_of GO:0043010 ! camera-type eye development intersection_of: results_in_development_of UBERON:0000966 ! retina relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_development_of UBERON:0000966 ! retina [Term] id: GO:0060042 name: retina morphogenesis in camera-type eye namespace: biological_process def: "The process in which the anatomical structure of the retina is generated and organized." [GOC:bf, GOC:dph, GOC:mtg_sensu] synonym: "retina morphogenesis in camera-style eye" EXACT [] synonym: "retinogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000966 ! retina relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: results_in_morphogenesis_of UBERON:0000966 ! retina [Term] id: GO:0060043 name: regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "regulation of cardiomyocyte proliferation" RELATED [GOC:dph] synonym: "regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060038 ! cardiac muscle cell proliferation relationship: regulates GO:0060038 ! cardiac muscle cell proliferation [Term] id: GO:0060044 name: negative regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "negative regulation of heart muscle cell proliferation" EXACT [] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation relationship: negatively_regulates GO:0060038 ! cardiac muscle cell proliferation [Term] id: GO:0060045 name: positive regulation of cardiac muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." [GOC:dph, GOC:rph] synonym: "positive regulation of heart muscle cell proliferation" RELATED [] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0060043 ! regulation of cardiac muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060038 ! cardiac muscle cell proliferation relationship: positively_regulates GO:0060038 ! cardiac muscle cell proliferation [Term] id: GO:0060047 name: heart contraction namespace: biological_process def: "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." [GOC:dph] synonym: "cardiac contraction" RELATED [] synonym: "heart beating" EXACT [] synonym: "hemolymph circulation" RELATED [] is_a: GO:0003015 ! heart process relationship: part_of GO:0008015 ! blood circulation [Term] id: GO:0060048 name: cardiac muscle contraction namespace: biological_process def: "Muscle contraction of cardiac muscle tissue." [GOC:dph] synonym: "heart muscle contraction" EXACT [] is_a: GO:0006941 ! striated muscle contraction intersection_of: GO:0006936 ! muscle contraction intersection_of: occurs_in UBERON:0001133 ! cardiac muscle tissue relationship: occurs_in UBERON:0001133 ! cardiac muscle tissue relationship: part_of GO:0060047 ! heart contraction [Term] id: GO:0060065 name: uterus development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." [GOC:dph, GOC:ebc] synonym: "Mullerian tract development" RELATED [] is_a: GO:0048513 ! animal organ development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000995 ! uterus relationship: results_in_development_of UBERON:0000995 ! uterus [Term] id: GO:0060066 name: oviduct development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." [GOC:dph, GOC:ebc, http://www.thefreedictionary.com/oviduct] synonym: "fallopian tube development" NARROW [GOC:bf] synonym: "Mullerian tract development" RELATED [] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003889 ! fallopian tube relationship: results_in_development_of UBERON:0003889 ! fallopian tube [Term] id: GO:0060073 name: micturition namespace: biological_process def: "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." [GOC:dph] synonym: "urination" EXACT [] synonym: "urine voiding" EXACT [] xref: Wikipedia:Urination is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion [Term] id: GO:0060083 name: smooth muscle contraction involved in micturition namespace: biological_process def: "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." [GOC:dph, PMID:15827347] synonym: "smooth muscle contraction involved in urination" RELATED [] synonym: "urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:dph] is_a: GO:0014832 ! urinary bladder smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: part_of GO:0060073 ! micturition relationship: part_of GO:0060073 ! micturition [Term] id: GO:0060084 name: synaptic transmission involved in micturition namespace: biological_process def: "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." [GOC:dph, PMID:15827347] synonym: "synaptic transmission involved in urination" RELATED [] is_a: GO:0007274 ! neuromuscular synaptic transmission intersection_of: GO:0007268 ! chemical synaptic transmission intersection_of: part_of GO:0060073 ! micturition relationship: part_of GO:0060073 ! micturition [Term] id: GO:0060096 name: serotonin secretion, neurotransmission namespace: biological_process def: "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." [GOC:dph] synonym: "serotonin release, neurotransmission" RELATED [GOC:tb] is_a: GO:0001820 ! serotonin secretion is_a: GO:0007269 ! neurotransmitter secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: has_primary_input CHEBI:350546 ! serotonin(1+) [Term] id: GO:0060135 name: maternal process involved in female pregnancy namespace: biological_process def: "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process relationship: part_of GO:0007565 ! female pregnancy [Term] id: GO:0060136 name: embryonic process involved in female pregnancy namespace: biological_process def: "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." [GOC:dph] is_a: GO:0048609 ! multicellular organismal reproductive process intersection_of: GO:0022414 ! reproductive process intersection_of: part_of GO:0007565 ! female pregnancy intersection_of: part_of GO:0009790 ! embryo development relationship: part_of GO:0007565 ! female pregnancy relationship: part_of GO:0009792 ! embryo development ending in birth or egg hatching [Term] id: GO:0060142 name: regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000768 ! syncytium formation by plasma membrane fusion relationship: regulates GO:0000768 ! syncytium formation by plasma membrane fusion [Term] id: GO:0060143 name: positive regulation of syncytium formation by plasma membrane fusion namespace: biological_process def: "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0060142 ! regulation of syncytium formation by plasma membrane fusion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion relationship: positively_regulates GO:0000768 ! syncytium formation by plasma membrane fusion [Term] id: GO:0060157 name: urinary bladder development namespace: biological_process def: "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." [GOC:dph, GOC:ln, GOC:mr, PMID:11768524, PMID:18276178, PMID:538956] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001255 ! urinary bladder relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0001255 ! urinary bladder property_value: RO:0002161 NCBITaxon:8782 [Term] id: GO:0060166 name: olfactory pit development namespace: biological_process def: "The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx." [GOC:dph, ISBN:0124020607] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005870 ! olfactory pit relationship: part_of GO:0043584 ! nose development relationship: results_in_development_of UBERON:0005870 ! olfactory pit property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22589" xsd:anyURI [Term] id: GO:0060170 name: ciliary membrane namespace: cellular_component alt_id: GO:0020017 def: "The portion of the plasma membrane surrounding a cilium." [GOC:cilia, GOC:dph, GOC:rph] comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. synonym: "cilial membrane" EXACT [] synonym: "cilium membrane" EXACT [] synonym: "flagellar membrane" NARROW [] synonym: "flagellum membrane" NARROW [] is_a: GO:0031253 ! cell projection membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0005929 ! cilium relationship: bounding_layer_of GO:0005929 ! cilium relationship: part_of GO:0005929 ! cilium [Term] id: GO:0060173 name: limb development namespace: biological_process def: "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." [GOC:dgh, GOC:dph, PMID:11487378] synonym: "limb bud development" NARROW [GOC:dph] synonym: "paired limb/fin development" EXACT [] xref: Wikipedia:Limb_development is_a: GO:0048736 ! appendage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004708 ! paired limb/fin relationship: results_in_development_of UBERON:0004708 ! paired limb/fin [Term] id: GO:0060174 name: limb bud formation namespace: biological_process def: "The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable." [GOC:dgh, GOC:dph] synonym: "limb formation" EXACT [] synonym: "limbbud formation" EXACT [] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002101 ! limb relationship: part_of GO:0035108 ! limb morphogenesis relationship: results_in_formation_of UBERON:0002101 ! limb [Term] id: GO:0060214 name: endocardium formation namespace: biological_process def: "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:bf, GOC:dph, PMID:17722983] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002165 ! endocardium relationship: part_of GO:0003160 ! endocardium morphogenesis relationship: results_in_formation_of UBERON:0002165 ! endocardium [Term] id: GO:0060218 name: hematopoietic stem cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:bf, GOC:BHF, GOC:dph, GOC:rl, PMID:15378083] synonym: "haematopoietic stem cell differentiation" EXACT [] synonym: "haemopoietic stem cell differentiation" EXACT [] synonym: "hemopoietic stem cell differentiation" EXACT [] is_a: GO:0002244 ! hematopoietic progenitor cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000037 ! hematopoietic stem cell relationship: results_in_acquisition_of_features_of CL:0000037 ! hematopoietic stem cell [Term] id: GO:0060219 name: camera-type eye photoreceptor cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0001754 ! eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010009 ! camera-type eye photoreceptor cell relationship: part_of GO:0003407 ! neural retina development relationship: part_of GO:0060042 ! retina morphogenesis in camera-type eye relationship: results_in_acquisition_of_features_of CL:0010009 ! camera-type eye photoreceptor cell [Term] id: GO:0060221 name: retinal rod cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." [GOC:dph] is_a: GO:0060219 ! camera-type eye photoreceptor cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000604 ! retinal rod cell relationship: results_in_acquisition_of_features_of CL:0000604 ! retinal rod cell [Term] id: GO:0060231 name: mesenchymal to epithelial transition namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "epithelial cell differentiation from mesenchymal cell" EXACT [GOC:BHF, GOC:dph, GOC:rl] synonym: "mesenchymal-epithelial transition" EXACT [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: has_input CL:0008019 ! mesenchymal cell intersection_of: results_in_acquisition_of_features_of CL:0000066 ! epithelial cell relationship: has_input CL:0008019 ! mesenchymal cell [Term] id: GO:0060251 name: regulation of glial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glial cell proliferation." [GOC:dph, GOC:tb] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014009 ! glial cell proliferation relationship: regulates GO:0014009 ! glial cell proliferation [Term] id: GO:0060252 name: positive regulation of glial cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014009 ! glial cell proliferation relationship: positively_regulates GO:0014009 ! glial cell proliferation [Term] id: GO:0060253 name: negative regulation of glial cell proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of glial cell proliferation." [GOC:dph, GOC:sl, GOC:tb] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0060251 ! regulation of glial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014009 ! glial cell proliferation relationship: negatively_regulates GO:0014009 ! glial cell proliferation [Term] id: GO:0060255 name: regulation of macromolecule metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." [GOC:dph, GOC:tb] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043170 ! macromolecule metabolic process relationship: regulates GO:0043170 ! macromolecule metabolic process [Term] id: GO:0060271 name: cilium assembly namespace: biological_process alt_id: GO:0042384 def: "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:BHF, GOC:cilia, GOC:dph, GOC:kmv, GOC:pr, GOC:vw, ISBN:0198506732, PMID:13978319, PMID:27350441, Reactome:R-HSA-5617833.2] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "ciliogenesis" EXACT [] synonym: "cilium biogenesis" RELATED [GOC:mah] synonym: "cilium formation" EXACT [] synonym: "cilium morphogenesis" RELATED [] synonym: "cilium organization" RELATED [GOC:dph] synonym: "microtubule-based flagellum assembly" EXACT [] xref: Reactome:R-HSA-5617833.2 is_a: GO:0044782 ! cilium organization is_a: GO:0070925 ! organelle assembly is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005929 ! cilium relationship: has_part GO:0035082 ! axoneme assembly relationship: has_part GO:0035735 ! intraciliary transport involved in cilium assembly relationship: has_part GO:0061512 ! protein localization to cilium relationship: has_part GO:0097712 ! vesicle targeting, trans-Golgi to periciliary membrane compartment relationship: has_part GO:1905349 ! ciliary transition zone assembly relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: results_in_assembly_of GO:0005929 ! cilium relationship: starts_with GO:0097711 ! ciliary basal body-plasma membrane docking property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 [Term] id: GO:0060281 name: regulation of oocyte development namespace: biological_process def: "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb, PMID:2394318] is_a: GO:1905879 ! regulation of oogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048599 ! oocyte development relationship: regulates GO:0048599 ! oocyte development [Term] id: GO:0060282 name: positive regulation of oocyte development namespace: biological_process def: "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048599 ! oocyte development relationship: positively_regulates GO:0048599 ! oocyte development [Term] id: GO:0060283 name: negative regulation of oocyte development namespace: biological_process def: "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." [GOC:dph, GOC:tb] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0060281 ! regulation of oocyte development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048599 ! oocyte development relationship: negatively_regulates GO:0048599 ! oocyte development [Term] id: GO:0060284 name: regulation of cell development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [GOC:dph, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048468 ! cell development relationship: regulates GO:0048468 ! cell development [Term] id: GO:0060285 name: cilium-dependent cell motility namespace: biological_process alt_id: GO:0071974 def: "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." [GOC:cilia, GOC:dgh, GOC:dph, GOC:krc, GOC:mlg, GOC:mtg_cambridge_2013] comment: Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent. synonym: "ciliary cell motility" RELATED [] synonym: "cilium cell motility" EXACT [] synonym: "microtubule-based flagellar cell motility" EXACT [] is_a: GO:0001539 ! cilium or flagellum-dependent cell motility relationship: has_part GO:0003341 ! cilium movement [Term] id: GO:0060294 name: cilium movement involved in cell motility namespace: biological_process def: "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003341 ! cilium movement intersection_of: GO:0003341 ! cilium movement intersection_of: part_of GO:0048870 ! cell motility relationship: part_of GO:0060285 ! cilium-dependent cell motility [Term] id: GO:0060295 name: regulation of cilium movement involved in cell motility namespace: biological_process def: "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0003352 ! regulation of cilium movement is_a: GO:1902019 ! regulation of cilium-dependent cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060294 ! cilium movement involved in cell motility relationship: regulates GO:0060294 ! cilium movement involved in cell motility [Term] id: GO:0060297 name: regulation of sarcomere organization namespace: biological_process def: "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045214 ! sarcomere organization relationship: regulates GO:0045214 ! sarcomere organization [Term] id: GO:0060298 name: positive regulation of sarcomere organization namespace: biological_process def: "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "positive regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902905 ! positive regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045214 ! sarcomere organization relationship: positively_regulates GO:0045214 ! sarcomere organization [Term] id: GO:0060299 name: negative regulation of sarcomere organization namespace: biological_process def: "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." [GOC:BHF, GOC:dph, GOC:tb] synonym: "negative regulation of sarcomere organisation" EXACT [GOC:mah] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:0060297 ! regulation of sarcomere organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045214 ! sarcomere organization relationship: negatively_regulates GO:0045214 ! sarcomere organization [Term] id: GO:0060322 name: head development namespace: biological_process def: "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000033 ! head relationship: results_in_development_of UBERON:0000033 ! head [Term] id: GO:0060323 name: head morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000033 ! head relationship: part_of GO:0010171 ! body morphogenesis relationship: part_of GO:0060322 ! head development relationship: results_in_morphogenesis_of UBERON:0000033 ! head [Term] id: GO:0060324 name: face development namespace: biological_process def: "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001456 ! face relationship: part_of GO:0060322 ! head development relationship: results_in_development_of UBERON:0001456 ! face [Term] id: GO:0060325 name: face morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001456 ! face relationship: part_of GO:0060323 ! head morphogenesis relationship: part_of GO:0060324 ! face development relationship: results_in_morphogenesis_of UBERON:0001456 ! face [Term] id: GO:0060341 name: regulation of cellular localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." [GOC:dph, GOC:tb] synonym: "regulation of cellular localisation" EXACT [GOC:mah] is_a: GO:0032879 ! regulation of localization is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051641 ! cellular localization relationship: regulates GO:0051641 ! cellular localization [Term] id: GO:0060343 name: trabecula formation namespace: biological_process def: "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] synonym: "trabecula biogenesis" RELATED [GOC:dph] synonym: "trabeculation" EXACT [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000440 ! trabecula relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: part_of GO:0061383 ! trabecula morphogenesis relationship: results_in_formation_of UBERON:0000440 ! trabecula [Term] id: GO:0060344 name: liver trabecula formation namespace: biological_process def: "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "liver trabecula biogenesis" RELATED [] synonym: "liver trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0010183 ! liver trabecula relationship: part_of GO:0001889 ! liver development relationship: results_in_formation_of UBERON:0010183 ! liver trabecula [Term] id: GO:0060345 name: spleen trabecula formation namespace: biological_process def: "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "spleen trabecula biogenesis" RELATED [GOC:dph] synonym: "spleen trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001265 ! trabecula of spleen relationship: part_of GO:0048536 ! spleen development relationship: results_in_formation_of UBERON:0001265 ! trabecula of spleen [Term] id: GO:0060347 name: heart trabecula formation namespace: biological_process def: "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod." [GOC:dph] synonym: "cardiac trabecula formation" EXACT [GOC:dph] synonym: "cardiac trabeculation" EXACT [GOC:dph] synonym: "heart trabecula biogenesis" RELATED [GOC:dph] synonym: "heart trabeculation" EXACT [GOC:dph] is_a: GO:0060343 ! trabecula formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002511 ! trabecula carnea relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: part_of GO:0061384 ! heart trabecula morphogenesis relationship: results_in_formation_of UBERON:0002511 ! trabecula carnea [Term] id: GO:0060348 name: bone development namespace: biological_process def: "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048513 ! animal organ development intersection_of: results_in_development_of UBERON:0001474 ! bone element relationship: part_of GO:0001501 ! skeletal system development relationship: results_in_development_of UBERON:0001474 ! bone element [Term] id: GO:0060349 name: bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001474 ! bone element relationship: part_of GO:0048705 ! skeletal system morphogenesis relationship: part_of GO:0060348 ! bone development relationship: results_in_morphogenesis_of UBERON:0001474 ! bone element [Term] id: GO:0060350 name: endochondral bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." [GOC:dph, PMID:11680679] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002513 ! endochondral bone relationship: results_in_morphogenesis_of UBERON:0002513 ! endochondral bone [Term] id: GO:0060351 name: cartilage development involved in endochondral bone morphogenesis namespace: biological_process def: "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." [GOC:dph] is_a: GO:0051216 ! cartilage development intersection_of: GO:0051216 ! cartilage development intersection_of: part_of GO:0060350 ! endochondral bone morphogenesis relationship: part_of GO:0060350 ! endochondral bone morphogenesis [Term] id: GO:0060359 name: response to ammonium ion namespace: biological_process alt_id: GO:1903717 def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:23509267] synonym: "response to ammonia" EXACT [] is_a: GO:0010035 ! response to inorganic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:28938 ! ammonium relationship: has_input CHEBI:28938 ! ammonium [Term] id: GO:0060363 name: cranial suture morphogenesis namespace: biological_process def: "The process in which any suture between cranial bones is generated and organized." [GOC:dph, GOC:pr, GOC:sl] is_a: GO:0097094 ! craniofacial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003685 ! cranial suture relationship: results_in_morphogenesis_of UBERON:0003685 ! cranial suture [Term] id: GO:0060364 name: frontal suture morphogenesis namespace: biological_process def: "The process in which the frontal suture is generated and organized." [GOC:dph, GOC:sl] synonym: "interfrontal suture morphogenesis" EXACT [] is_a: GO:0060363 ! cranial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002490 ! frontal suture relationship: results_in_morphogenesis_of UBERON:0002490 ! frontal suture [Term] id: GO:0060379 name: cardiac muscle cell myoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:dph, GOC:tb] synonym: "cardiac myoblast differentiation" RELATED [GOC:dph, GOC:tb] synonym: "myocardial precursor cell differentiation" EXACT [GOC:mtg_heart] is_a: GO:0010002 ! cardioblast differentiation is_a: GO:0045445 ! myoblast differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000513 ! cardiac muscle myoblast relationship: results_in_acquisition_of_features_of CL:0000513 ! cardiac muscle myoblast [Term] id: GO:0060404 name: axonemal microtubule depolymerization namespace: biological_process def: "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." [GOC:cilia, GOC:dph, GOC:krc, GOC:tb] is_a: GO:0010938 ! cytoplasmic microtubule depolymerization is_a: GO:0061523 ! cilium disassembly intersection_of: GO:0007019 ! microtubule depolymerization intersection_of: occurs_in GO:0005930 ! axoneme relationship: occurs_in GO:0005930 ! axoneme [Term] id: GO:0060408 name: regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0033238 ! regulation of amine metabolic process is_a: GO:0080090 ! regulation of primary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008291 ! acetylcholine metabolic process relationship: regulates GO:0008291 ! acetylcholine metabolic process [Term] id: GO:0060409 name: positive regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0033240 ! positive regulation of amine metabolic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008291 ! acetylcholine metabolic process relationship: positively_regulates GO:0008291 ! acetylcholine metabolic process [Term] id: GO:0060410 name: negative regulation of acetylcholine metabolic process namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." [GOC:dph, GOC:tb] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0033239 ! negative regulation of amine metabolic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008291 ! acetylcholine metabolic process relationship: negatively_regulates GO:0008291 ! acetylcholine metabolic process [Term] id: GO:0060411 name: cardiac septum morphogenesis namespace: biological_process alt_id: GO:0003280 def: "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." [GOC:dph, GOC:mtg_heart] synonym: "heart septum morphogenesis" EXACT [] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002099 ! cardiac septum relationship: part_of GO:0003206 ! cardiac chamber morphogenesis relationship: part_of GO:0003279 ! cardiac septum development relationship: results_in_morphogenesis_of UBERON:0002099 ! cardiac septum [Term] id: GO:0060412 name: ventricular septum morphogenesis namespace: biological_process def: "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." [GOC:dph] synonym: "interventricular septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002094 ! interventricular septum relationship: part_of GO:0003281 ! ventricular septum development relationship: results_in_morphogenesis_of UBERON:0002094 ! interventricular septum [Term] id: GO:0060413 name: atrial septum morphogenesis namespace: biological_process alt_id: GO:0003287 def: "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." [GOC:dph, GOC:mtg_heart] synonym: "interatrial septum morphogenesis" EXACT [GOC:dph] is_a: GO:0060411 ! cardiac septum morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002085 ! interatrial septum relationship: part_of GO:0003209 ! cardiac atrium morphogenesis relationship: part_of GO:0003283 ! atrial septum development relationship: results_in_morphogenesis_of UBERON:0002085 ! interatrial septum [Term] id: GO:0060414 name: aorta smooth muscle tissue morphogenesis namespace: biological_process def: "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." [GOC:bf, GOC:dgh, GOC:dph, Wikipedia:Aorta] is_a: GO:0060415 ! muscle tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004178 ! aorta smooth muscle tissue relationship: part_of GO:0035909 ! aorta morphogenesis relationship: part_of GO:0048745 ! smooth muscle tissue development relationship: results_in_morphogenesis_of UBERON:0004178 ! aorta smooth muscle tissue [Term] id: GO:0060415 name: muscle tissue morphogenesis namespace: biological_process def: "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0048729 ! tissue morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002385 ! muscle tissue relationship: part_of GO:0048644 ! muscle organ morphogenesis relationship: results_in_morphogenesis_of UBERON:0002385 ! muscle tissue [Term] id: GO:0060419 name: heart growth namespace: biological_process def: "The increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0000948 ! heart relationship: part_of GO:0007507 ! heart development relationship: results_in_growth_of UBERON:0000948 ! heart [Term] id: GO:0060420 name: regulation of heart growth namespace: biological_process def: "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:tb] is_a: GO:0046620 ! regulation of organ growth is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060419 ! heart growth relationship: regulates GO:0060419 ! heart growth [Term] id: GO:0060421 name: positive regulation of heart growth namespace: biological_process def: "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:BHF, GOC:dph, GOC:tb] is_a: GO:0046622 ! positive regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060419 ! heart growth relationship: positively_regulates GO:0060419 ! heart growth [Term] id: GO:0060425 name: lung morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the lung are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002048 ! lung relationship: part_of GO:0030324 ! lung development relationship: results_in_morphogenesis_of UBERON:0002048 ! lung [Term] id: GO:0060426 name: lung vasculature development namespace: biological_process def: "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary vasculature development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000102 ! lung vasculature relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0000102 ! lung vasculature [Term] id: GO:0060427 name: lung connective tissue development namespace: biological_process def: "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary connective tissue development" EXACT [] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000114 ! lung connective tissue relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0000114 ! lung connective tissue [Term] id: GO:0060428 name: lung epithelium development namespace: biological_process def: "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary epithelium development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000115 ! lung epithelium relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0000115 ! lung epithelium [Term] id: GO:0060429 name: epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:dph, GOC:mtg_lung] subset: goslim_drosophila is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000483 ! epithelium relationship: results_in_development_of UBERON:0000483 ! epithelium [Term] id: GO:0060431 name: primary lung bud formation namespace: biological_process def: "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." [GOC:dph, GOC:mtg_lung] synonym: "lung formation" EXACT [GOC:dph] is_a: GO:0016331 ! morphogenesis of embryonic epithelium is_a: GO:0048645 ! animal organ formation is_a: GO:0060441 ! epithelial tube branching involved in lung morphogenesis is_a: GO:0060572 ! morphogenesis of an epithelial bud intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002048 ! lung relationship: results_in_formation_of UBERON:0002048 ! lung [Term] id: GO:0060433 name: bronchus development namespace: biological_process def: "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph] is_a: GO:0030323 ! respiratory tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002185 ! bronchus relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0002185 ! bronchus [Term] id: GO:0060434 name: bronchus morphogenesis namespace: biological_process def: "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002185 ! bronchus relationship: part_of GO:0060433 ! bronchus development relationship: results_in_morphogenesis_of UBERON:0002185 ! bronchus [Term] id: GO:0060435 name: bronchiole development namespace: biological_process def: "The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." [GOC:dph, GOC:mtg_lung] is_a: GO:0030323 ! respiratory tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002186 ! bronchiole relationship: part_of GO:0030324 ! lung development relationship: results_in_development_of UBERON:0002186 ! bronchiole [Term] id: GO:0060436 name: bronchiole morphogenesis namespace: biological_process def: "The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." [GOC:dph] is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002186 ! bronchiole relationship: part_of GO:0060435 ! bronchiole development relationship: results_in_morphogenesis_of UBERON:0002186 ! bronchiole [Term] id: GO:0060437 name: lung growth namespace: biological_process def: "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." [GOC:dph] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0002048 ! lung relationship: part_of GO:0030324 ! lung development relationship: results_in_growth_of UBERON:0002048 ! lung [Term] id: GO:0060438 name: trachea development namespace: biological_process def: "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001005 ! respiratory airway relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0001005 ! respiratory airway [Term] id: GO:0060439 name: trachea morphogenesis namespace: biological_process def: "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001005 ! respiratory airway relationship: part_of GO:0060438 ! trachea development relationship: results_in_morphogenesis_of UBERON:0001005 ! respiratory airway [Term] id: GO:0060440 name: trachea formation namespace: biological_process def: "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." [GOC:dph] is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001005 ! respiratory airway relationship: part_of GO:0060439 ! trachea morphogenesis relationship: results_in_formation_of UBERON:0001005 ! respiratory airway [Term] id: GO:0060441 name: epithelial tube branching involved in lung morphogenesis namespace: biological_process def: "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:mtg_lung] synonym: "lung branching morphogenesis" EXACT [GOC:dph] is_a: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: GO:0048754 ! branching morphogenesis of an epithelial tube intersection_of: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060425 ! lung morphogenesis [Term] id: GO:0060450 name: positive regulation of hindgut contraction namespace: biological_process def: "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0043133 ! hindgut contraction relationship: positively_regulates GO:0043133 ! hindgut contraction [Term] id: GO:0060451 name: negative regulation of hindgut contraction namespace: biological_process def: "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." [GOC:dph, GOC:tb] is_a: GO:0043134 ! regulation of hindgut contraction is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0043133 ! hindgut contraction relationship: negatively_regulates GO:0043133 ! hindgut contraction [Term] id: GO:0060452 name: positive regulation of cardiac muscle contraction namespace: biological_process def: "Any process that increases the frequency, rate or extent of cardiac muscle contraction." [GOC:dph, GOC:tb] is_a: GO:0045823 ! positive regulation of heart contraction is_a: GO:0045989 ! positive regulation of striated muscle contraction is_a: GO:0055117 ! regulation of cardiac muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060048 ! cardiac muscle contraction relationship: positively_regulates GO:0060048 ! cardiac muscle contraction [Term] id: GO:0060453 name: regulation of gastric acid secretion namespace: biological_process def: "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001696 ! gastric acid secretion relationship: regulates GO:0001696 ! gastric acid secretion [Term] id: GO:0060454 name: positive regulation of gastric acid secretion namespace: biological_process def: "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060456 ! positive regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001696 ! gastric acid secretion relationship: positively_regulates GO:0001696 ! gastric acid secretion [Term] id: GO:0060455 name: negative regulation of gastric acid secretion namespace: biological_process def: "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." [GOC:dph, GOC:tb] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060453 ! regulation of gastric acid secretion is_a: GO:0060457 ! negative regulation of digestive system process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001696 ! gastric acid secretion relationship: negatively_regulates GO:0001696 ! gastric acid secretion [Term] id: GO:0060456 name: positive regulation of digestive system process namespace: biological_process def: "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022600 ! digestive system process relationship: positively_regulates GO:0022600 ! digestive system process [Term] id: GO:0060457 name: negative regulation of digestive system process namespace: biological_process def: "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." [GOC:dph, GOC:tb] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022600 ! digestive system process relationship: negatively_regulates GO:0022600 ! digestive system process [Term] id: GO:0060458 name: right lung development namespace: biological_process def: "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "right pulmonary development" EXACT [GOC:dph, GOC:mtg_lung] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002167 ! right lung relationship: results_in_development_of UBERON:0002167 ! right lung [Term] id: GO:0060459 name: left lung development namespace: biological_process def: "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." [GOC:dph, GOC:mtg_lung] synonym: "left pulmonary development" EXACT [GOC:dph] is_a: GO:0030324 ! lung development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002168 ! left lung relationship: results_in_development_of UBERON:0002168 ! left lung [Term] id: GO:0060460 name: left lung morphogenesis namespace: biological_process def: "The process in which anatomical structures of the left lung are generated and organized." [GOC:dph] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002168 ! left lung relationship: part_of GO:0060459 ! left lung development relationship: results_in_morphogenesis_of UBERON:0002168 ! left lung [Term] id: GO:0060461 name: right lung morphogenesis namespace: biological_process def: "The process in which anatomical structures of the right lung are generated and organized." [GOC:dph, GOC:mtg_lung] is_a: GO:0060425 ! lung morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002167 ! right lung relationship: part_of GO:0060458 ! right lung development relationship: results_in_morphogenesis_of UBERON:0002167 ! right lung [Term] id: GO:0060465 name: pharynx development namespace: biological_process def: "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." [GOC:dph, GOC:rk] synonym: "pharyngeal development" RELATED [] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006562 ! pharynx relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_development_of UBERON:0006562 ! pharynx [Term] id: GO:0060467 name: negative regulation of fertilization namespace: biological_process def: "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:dph] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009566 ! fertilization relationship: negatively_regulates GO:0009566 ! fertilization [Term] id: GO:0060468 name: prevention of polyspermy namespace: biological_process def: "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." [GOC:dph] synonym: "negative regulation of fertilization involved in egg activation" EXACT [GOC:dph] synonym: "polyspermy block" EXACT [GOC:dph] is_a: GO:0022414 ! reproductive process is_a: GO:0060467 ! negative regulation of fertilization intersection_of: GO:0060467 ! negative regulation of fertilization intersection_of: part_of GO:0007343 ! egg activation relationship: part_of GO:0007343 ! egg activation [Term] id: GO:0060474 name: positive regulation of flagellated sperm motility involved in capacitation namespace: biological_process def: "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence." [GOC:cilia, GOC:dph, GOC:krc] synonym: "positive regulation of sperm motility involved in capacitation" RELATED [] is_a: GO:0022414 ! reproductive process is_a: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: GO:1902093 ! positive regulation of flagellated sperm motility intersection_of: part_of GO:0048240 ! sperm capacitation relationship: part_of GO:0048240 ! sperm capacitation [Term] id: GO:0060479 name: lung cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary cell differentiation" EXACT [GOC:dph] is_a: GO:0030154 ! cell differentiation relationship: part_of GO:0030324 ! lung development [Term] id: GO:0060485 name: mesenchyme development namespace: biological_process def: "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:dph] synonym: "mesenchymal development" EXACT [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003104 ! mesenchyme relationship: part_of GO:0048513 ! animal organ development relationship: results_in_development_of UBERON:0003104 ! mesenchyme [Term] id: GO:0060486 name: club cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles." [GOC:dph, GOC:mtg_lung, PMID:28144783] synonym: "Clara cell differentiation" EXACT [PMID:28144783] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000158 ! club cell relationship: results_in_acquisition_of_features_of CL:0000158 ! club cell [Term] id: GO:0060487 name: lung epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." [GOC:dph] synonym: "pulmonary epithelial cell differentiation" RELATED [GOC:dph] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060479 ! lung cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000082 ! epithelial cell of lung relationship: part_of GO:0060428 ! lung epithelium development relationship: results_in_acquisition_of_features_of CL:0000082 ! epithelial cell of lung [Term] id: GO:0060491 name: regulation of cell projection assembly namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cell projection assembly." [GOC:dph, GOC:tb] synonym: "regulation of cell projection formation" RELATED [GOC:dph, GOC:tb] is_a: GO:0031344 ! regulation of cell projection organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030031 ! cell projection assembly relationship: regulates GO:0030031 ! cell projection assembly [Term] id: GO:0060495 name: cell-cell signaling involved in lung development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." [GOC:dph, GOC:mtg_lung] synonym: "cell-cell signalling involved in lung development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0030324 ! lung development relationship: part_of GO:0030324 ! lung development [Term] id: GO:0060501 name: positive regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." [GOC:dph] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis relationship: positively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis [Term] id: GO:0060502 name: epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." [GOC:dph] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060425 ! lung morphogenesis relationship: part_of GO:0060428 ! lung epithelium development [Term] id: GO:0060532 name: bronchus cartilage development namespace: biological_process def: "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph, GOC:mtg_lung] synonym: "pulmonary cartilage development" EXACT [] is_a: GO:0051216 ! cartilage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001956 ! cartilage of bronchus relationship: part_of GO:0060433 ! bronchus development relationship: results_in_development_of UBERON:0001956 ! cartilage of bronchus created_by: dph creation_date: 2009-04-10T08:12:06Z [Term] id: GO:0060533 name: bronchus cartilage morphogenesis namespace: biological_process def: "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs." [GOC:dph] is_a: GO:0060536 ! cartilage morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001956 ! cartilage of bronchus relationship: part_of GO:0060434 ! bronchus morphogenesis relationship: part_of GO:0060532 ! bronchus cartilage development relationship: results_in_morphogenesis_of UBERON:0001956 ! cartilage of bronchus created_by: dph creation_date: 2009-04-10T08:47:41Z [Term] id: GO:0060534 name: trachea cartilage development namespace: biological_process def: "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051216 ! cartilage development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003604 ! trachea cartilage relationship: part_of GO:0060438 ! trachea development relationship: results_in_development_of UBERON:0003604 ! trachea cartilage created_by: dph creation_date: 2009-04-10T09:00:18Z [Term] id: GO:0060535 name: trachea cartilage morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cartilage in the trachea are generated and organized." [GOC:dph] is_a: GO:0060536 ! cartilage morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003604 ! trachea cartilage relationship: part_of GO:0060439 ! trachea morphogenesis relationship: part_of GO:0060534 ! trachea cartilage development relationship: results_in_morphogenesis_of UBERON:0003604 ! trachea cartilage created_by: dph creation_date: 2009-04-10T09:07:48Z [Term] id: GO:0060536 name: cartilage morphogenesis namespace: biological_process def: "The process in which the anatomical structures of cartilage are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007844 ! cartilage element relationship: part_of GO:0051216 ! cartilage development relationship: results_in_morphogenesis_of UBERON:0007844 ! cartilage element created_by: dph creation_date: 2009-04-10T09:13:27Z [Term] id: GO:0060537 name: muscle tissue development namespace: biological_process def: "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." [GOC:dph] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002385 ! muscle tissue relationship: results_in_development_of UBERON:0002385 ! muscle tissue created_by: dph creation_date: 2009-04-10T08:05:37Z [Term] id: GO:0060538 name: skeletal muscle organ development namespace: biological_process def: "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." [GOC:dph] is_a: GO:0007517 ! muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0014892 ! skeletal muscle organ relationship: results_in_development_of UBERON:0014892 ! skeletal muscle organ created_by: dph creation_date: 2009-04-10T08:25:12Z [Term] id: GO:0060539 name: diaphragm development namespace: biological_process def: "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." [GOC:dph] is_a: GO:0060538 ! skeletal muscle organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001103 ! diaphragm relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0001103 ! diaphragm property_value: RO:0002161 NCBITaxon:8782 created_by: dph creation_date: 2009-04-10T08:44:56Z [Term] id: GO:0060540 name: diaphragm morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the diaphragm are generated and organized." [GOC:dph] is_a: GO:0048644 ! muscle organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001103 ! diaphragm relationship: part_of GO:0060539 ! diaphragm development relationship: results_in_morphogenesis_of UBERON:0001103 ! diaphragm property_value: RO:0002161 NCBITaxon:8782 created_by: dph creation_date: 2009-04-10T08:47:51Z [Term] id: GO:0060541 name: respiratory system development namespace: biological_process def: "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." [GOC:dph] subset: goslim_drosophila is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001004 ! respiratory system relationship: results_in_development_of UBERON:0001004 ! respiratory system created_by: dph creation_date: 2009-04-10T08:55:42Z [Term] id: GO:0060560 name: developmental growth involved in morphogenesis namespace: biological_process def: "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." [GOC:dph] synonym: "differential growth" EXACT [GOC:dph] is_a: GO:0048589 ! developmental growth intersection_of: GO:0048589 ! developmental growth intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009653 ! anatomical structure morphogenesis created_by: dph creation_date: 2009-04-28T08:42:53Z [Term] id: GO:0060561 name: apoptotic process involved in morphogenesis namespace: biological_process def: "Any apoptotic process that contributes to the shaping of an anatomical structure." [GOC:dph, GOC:mtg_apoptosis] synonym: "apoptosis involved in development" RELATED [] synonym: "apoptosis involved in morphogenesis" NARROW [] synonym: "morphogenetic apoptosis" RELATED [GOC:dph] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0009653 ! anatomical structure morphogenesis created_by: dph creation_date: 2009-04-28T09:17:27Z [Term] id: GO:0060562 name: epithelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003914 ! epithelial tube relationship: results_in_morphogenesis_of UBERON:0003914 ! epithelial tube created_by: dph creation_date: 2009-04-28T09:33:36Z [Term] id: GO:0060563 name: neuroepithelial cell differentiation namespace: biological_process def: "The process in which epiblast cells acquire specialized features of neuroepithelial cells." [GOC:dph, GOC:tb] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000710 ! neurecto-epithelial cell relationship: results_in_acquisition_of_features_of CL:0000710 ! neurecto-epithelial cell created_by: dph creation_date: 2009-04-29T01:50:05Z [Term] id: GO:0060571 name: morphogenesis of an epithelial fold namespace: biological_process def: "The morphogenetic process in which an epithelial sheet bends along a linear axis." [GOC:dph] synonym: "epithelial folding" EXACT [GOC:dph] synonym: "folding of an epithelial sheet" RELATED [GOC:dph] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005157 ! epithelial fold relationship: results_in_morphogenesis_of UBERON:0005157 ! epithelial fold created_by: dph creation_date: 2009-04-30T09:27:17Z [Term] id: GO:0060572 name: morphogenesis of an epithelial bud namespace: biological_process def: "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." [GOC:dph] is_a: GO:0060571 ! morphogenesis of an epithelial fold intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005153 ! epithelial bud relationship: results_in_morphogenesis_of UBERON:0005153 ! epithelial bud created_by: dph creation_date: 2009-04-30T09:38:35Z [Term] id: GO:0060574 name: intestinal epithelial cell maturation namespace: biological_process def: "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." [GOC:dph, PMID:18824147] is_a: GO:0002069 ! columnar/cuboidal epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0002563 ! intestinal epithelial cell relationship: part_of GO:0060576 ! intestinal epithelial cell development relationship: results_in_maturation_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:10:41Z [Term] id: GO:0060575 name: intestinal epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." [GOC:dph] is_a: GO:0002065 ! columnar/cuboidal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002563 ! intestinal epithelial cell relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_acquisition_of_features_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:17:56Z [Term] id: GO:0060576 name: intestinal epithelial cell development namespace: biological_process def: "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0002066 ! columnar/cuboidal epithelial cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0002563 ! intestinal epithelial cell relationship: part_of GO:0060575 ! intestinal epithelial cell differentiation relationship: results_in_development_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2009-05-06T08:20:24Z [Term] id: GO:0060577 name: pulmonary vein morphogenesis namespace: biological_process def: "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." [GOC:dph] synonym: "pulmonary venous blood vessel morphogenesis" RELATED [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002016 ! pulmonary vein relationship: results_in_morphogenesis_of UBERON:0002016 ! pulmonary vein created_by: dph creation_date: 2009-05-06T08:44:04Z [Term] id: GO:0060578 name: superior vena cava morphogenesis namespace: biological_process def: "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." [GOC:dph] is_a: GO:0048845 ! venous blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001585 ! anterior vena cava relationship: results_in_morphogenesis_of UBERON:0001585 ! anterior vena cava created_by: dph creation_date: 2009-05-06T08:47:21Z [Term] id: GO:0060581 name: cell fate commitment involved in pattern specification namespace: biological_process def: "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." [GOC:dph] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: part_of GO:0007389 ! pattern specification process relationship: part_of GO:0007389 ! pattern specification process created_by: dph creation_date: 2009-05-07T12:40:55Z [Term] id: GO:0060591 name: chondroblast differentiation namespace: biological_process def: "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." [GOC:dph] synonym: "chondrocyte progenitor cell differentiation" RELATED [GOC:dph] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000058 ! chondroblast relationship: part_of GO:0051216 ! cartilage development relationship: results_in_acquisition_of_features_of CL:0000058 ! chondroblast created_by: dph creation_date: 2009-05-11T07:47:36Z [Term] id: GO:0060612 name: adipose tissue development namespace: biological_process def: "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." [GOC:dph] synonym: "adipogenesis" RELATED [GOC:mah, GOC:sl] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001013 ! adipose tissue relationship: part_of GO:0048513 ! animal organ development relationship: results_in_development_of UBERON:0001013 ! adipose tissue created_by: dph creation_date: 2009-05-15T12:36:28Z [Term] id: GO:0060623 name: regulation of chromosome condensation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." [GOC:dph, GOC:tb] is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030261 ! chromosome condensation relationship: regulates GO:0030261 ! chromosome condensation created_by: dph creation_date: 2009-05-18T02:12:13Z [Term] id: GO:0060627 name: regulation of vesicle-mediated transport namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." [GOC:dph, GOC:tb] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0016192 ! vesicle-mediated transport relationship: regulates GO:0016192 ! vesicle-mediated transport created_by: dph creation_date: 2009-05-18T02:29:43Z [Term] id: GO:0060632 name: regulation of microtubule-based movement namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007018 ! microtubule-based movement relationship: regulates GO:0007018 ! microtubule-based movement created_by: dph creation_date: 2009-05-18T03:07:02Z [Term] id: GO:0060669 name: embryonic placenta morphogenesis namespace: biological_process def: "The process in which the embryonic placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007106 ! chorionic villus relationship: part_of GO:0001892 ! embryonic placenta development relationship: results_in_morphogenesis_of UBERON:0007106 ! chorionic villus created_by: dph creation_date: 2009-06-02T09:33:37Z [Term] id: GO:0060670 name: branching involved in labyrinthine layer morphogenesis namespace: biological_process def: "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." [GOC:dph, PMID:16916377] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0060713 ! labyrinthine layer morphogenesis relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis created_by: dph creation_date: 2009-06-02T10:40:40Z [Term] id: GO:0060671 name: epithelial cell differentiation involved in embryonic placenta development namespace: biological_process def: "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." [GOC:dph, PMID:16916377] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0060706 ! cell differentiation involved in embryonic placenta development intersection_of: GO:0030855 ! epithelial cell differentiation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: part_of GO:0060711 ! labyrinthine layer development created_by: dph creation_date: 2009-06-02T11:40:52Z [Term] id: GO:0060673 name: cell-cell signaling involved in placenta development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another." [GOC:dph, PMID:16916377] synonym: "cell-cell signalling involved in placenta development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001890 ! placenta development relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-02T12:58:03Z [Term] id: GO:0060674 name: placenta blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." [GOC:dph, PMID:16916377] is_a: GO:0001568 ! blood vessel development relationship: part_of GO:0001890 ! placenta development created_by: dph creation_date: 2009-06-02T01:09:43Z [Term] id: GO:0060675 name: ureteric bud morphogenesis namespace: biological_process def: "The process in which the ureteric bud is generated and organized." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0072171 ! mesonephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000084 ! ureteric bud relationship: part_of GO:0001657 ! ureteric bud development relationship: results_in_morphogenesis_of UBERON:0000084 ! ureteric bud created_by: dph creation_date: 2009-06-02T01:31:41Z [Term] id: GO:0060676 name: ureteric bud formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." [GOC:dph, PMID:16916378] is_a: GO:0072172 ! mesonephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000084 ! ureteric bud relationship: part_of GO:0060675 ! ureteric bud morphogenesis relationship: results_in_formation_of UBERON:0000084 ! ureteric bud created_by: dph creation_date: 2009-06-02T01:47:23Z [Term] id: GO:0060688 name: regulation of morphogenesis of a branching structure namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." [GOC:dph] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001763 ! morphogenesis of a branching structure relationship: regulates GO:0001763 ! morphogenesis of a branching structure created_by: dph creation_date: 2009-06-05T12:41:44Z [Term] id: GO:0060706 name: cell differentiation involved in embryonic placenta development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-09T10:26:42Z [Term] id: GO:0060711 name: labyrinthine layer development namespace: biological_process def: "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003946 ! placenta labyrinth relationship: part_of GO:0001892 ! embryonic placenta development relationship: results_in_development_of UBERON:0003946 ! placenta labyrinth created_by: dph creation_date: 2009-06-09T03:27:43Z [Term] id: GO:0060713 name: labyrinthine layer morphogenesis namespace: biological_process def: "The process in which the labyrinthine layer of the placenta is generated and organized." [GOC:dph] is_a: GO:0048598 ! embryonic morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003946 ! placenta labyrinth relationship: part_of GO:0060669 ! embryonic placenta morphogenesis relationship: part_of GO:0060711 ! labyrinthine layer development relationship: results_in_morphogenesis_of UBERON:0003946 ! placenta labyrinth created_by: dph creation_date: 2009-06-10T08:10:19Z [Term] id: GO:0060714 name: labyrinthine layer formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003946 ! placenta labyrinth relationship: part_of GO:0060713 ! labyrinthine layer morphogenesis relationship: results_in_formation_of UBERON:0003946 ! placenta labyrinth created_by: dph creation_date: 2009-06-10T08:13:14Z [Term] id: GO:0060716 name: labyrinthine layer blood vessel development namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GOC:dph] is_a: GO:0048568 ! embryonic organ development is_a: GO:0060674 ! placenta blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004183 ! placental labyrinth blood vessel relationship: part_of GO:0060711 ! labyrinthine layer development relationship: results_in_development_of UBERON:0004183 ! placental labyrinth blood vessel created_by: dph creation_date: 2009-06-11T09:04:38Z [Term] id: GO:0060717 name: chorion development namespace: biological_process def: "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." [GOC:dph] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003124 ! chorion membrane relationship: results_in_development_of UBERON:0003124 ! chorion membrane created_by: dph creation_date: 2009-06-11T02:37:50Z [Term] id: GO:0060718 name: chorionic trophoblast cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." [CL:0011101, GOC:dph, PMID:16983341] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0011101 ! chorionic trophoblast cell relationship: part_of GO:0060717 ! chorion development relationship: results_in_acquisition_of_features_of CL:0011101 ! chorionic trophoblast cell created_by: dph creation_date: 2009-06-11T02:48:27Z [Term] id: GO:0060719 name: chorionic trophoblast cell development namespace: biological_process def: "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." [CL:0011101, GOC:16983341, GOC:dph] is_a: GO:0048468 ! cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0011101 ! chorionic trophoblast cell relationship: part_of GO:0060718 ! chorionic trophoblast cell differentiation relationship: results_in_development_of CL:0011101 ! chorionic trophoblast cell created_by: dph creation_date: 2009-06-11T02:58:45Z [Term] id: GO:0060722 name: cell proliferation involved in embryonic placenta development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." [GOC:dph] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001892 ! embryonic placenta development relationship: part_of GO:0001892 ! embryonic placenta development created_by: dph creation_date: 2009-06-12T12:46:04Z [Term] id: GO:0060723 name: regulation of cell proliferation involved in embryonic placenta development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development relationship: regulates GO:0060722 ! cell proliferation involved in embryonic placenta development created_by: dph creation_date: 2009-06-12T12:50:23Z [Term] id: GO:0060788 name: ectodermal placode formation namespace: biological_process def: "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005085 ! ectodermal placode relationship: part_of GO:0071697 ! ectodermal placode morphogenesis relationship: results_in_formation_of UBERON:0005085 ! ectodermal placode created_by: dph creation_date: 2009-08-04T12:15:57Z [Term] id: GO:0060790 name: tooth placode formation namespace: biological_process def: "The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060788 ! ectodermal placode formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005087 ! tooth placode relationship: part_of GO:0042475 ! odontogenesis of dentin-containing tooth relationship: results_in_formation_of UBERON:0005087 ! tooth placode created_by: dph creation_date: 2009-08-04T12:21:47Z [Term] id: GO:0060795 name: cell fate commitment involved in formation of primary germ layer namespace: biological_process def: "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045165 ! cell fate commitment intersection_of: GO:0045165 ! cell fate commitment intersection_of: part_of GO:0001704 ! formation of primary germ layer relationship: part_of GO:0001704 ! formation of primary germ layer created_by: dph creation_date: 2009-08-04T03:11:22Z [Term] id: GO:0060800 name: regulation of cell differentiation involved in embryonic placenta development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045595 ! regulation of cell differentiation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development relationship: regulates GO:0060706 ! cell differentiation involved in embryonic placenta development created_by: dph creation_date: 2009-08-06T01:20:25Z [Term] id: GO:0060806 name: negative regulation of cell differentiation involved in embryonic placenta development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0060800 ! regulation of cell differentiation involved in embryonic placenta development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development relationship: negatively_regulates GO:0060706 ! cell differentiation involved in embryonic placenta development created_by: dph creation_date: 2009-08-06T02:02:18Z [Term] id: GO:0060815 name: regulation of translation involved in anterior/posterior axis specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0006417 ! regulation of translation intersection_of: GO:0006417 ! regulation of translation intersection_of: part_of GO:0009948 ! anterior/posterior axis specification relationship: part_of GO:0009948 ! anterior/posterior axis specification created_by: dph creation_date: 2009-08-07T10:02:31Z [Term] id: GO:0060837 name: blood vessel endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0045446 ! endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000071 ! blood vessel endothelial cell relationship: part_of GO:0001568 ! blood vessel development relationship: results_in_acquisition_of_features_of CL:0000071 ! blood vessel endothelial cell created_by: dph creation_date: 2009-08-11T03:47:36Z [Term] id: GO:0060840 name: artery development namespace: biological_process def: "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001637 ! artery relationship: results_in_development_of UBERON:0001637 ! artery created_by: dph creation_date: 2009-08-12T10:10:51Z [Term] id: GO:0060841 name: venous blood vessel development namespace: biological_process def: "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001638 ! vein relationship: results_in_development_of UBERON:0001638 ! vein created_by: dph creation_date: 2009-08-12T10:14:07Z [Term] id: GO:0060842 name: arterial endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000413 ! endothelial cell of artery relationship: results_in_acquisition_of_features_of CL:1000413 ! endothelial cell of artery created_by: dph creation_date: 2009-08-12T10:41:34Z [Term] id: GO:0060843 name: venous endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002543 ! vein endothelial cell relationship: results_in_acquisition_of_features_of CL:0002543 ! vein endothelial cell created_by: dph creation_date: 2009-08-12T10:43:40Z [Term] id: GO:0060887 name: limb epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0098773 ! skin epidermis development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009200 ! limb epidermis relationship: part_of GO:0060173 ! limb development relationship: results_in_development_of UBERON:0009200 ! limb epidermis created_by: dph creation_date: 2009-08-13T12:39:39Z [Term] id: GO:0060896 name: neural plate pattern specification namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0007389 ! pattern specification process created_by: dph creation_date: 2009-08-13T02:06:27Z [Term] id: GO:0060897 name: neural plate regionalization namespace: biological_process def: "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0003002 ! regionalization is_a: GO:0060896 ! neural plate pattern specification created_by: dph creation_date: 2009-08-13T02:09:04Z [Term] id: GO:0060900 name: embryonic camera-type eye formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis relationship: part_of GO:0048596 ! embryonic camera-type eye morphogenesis created_by: dph creation_date: 2009-08-13T02:26:54Z [Term] id: GO:0060914 name: heart formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." [GOC:mtg_heart] synonym: "cardiogenesis" RELATED [GOC:mtg_heart] is_a: GO:0048645 ! animal organ formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000948 ! heart relationship: part_of GO:0003007 ! heart morphogenesis relationship: results_in_formation_of UBERON:0000948 ! heart created_by: dph creation_date: 2009-09-17T09:02:13Z [Term] id: GO:0060915 name: mesenchymal cell differentiation involved in lung development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [GOC:dph] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0030324 ! lung development relationship: part_of GO:0030324 ! lung development created_by: dph creation_date: 2009-09-18T11:45:33Z [Term] id: GO:0060916 name: mesenchymal cell proliferation involved in lung development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:dph] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0030324 ! lung development relationship: part_of GO:0030324 ! lung development created_by: dph creation_date: 2009-09-18T11:50:17Z [Term] id: GO:0060920 name: cardiac pacemaker cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "pacemaker cell differentiation" BROAD [] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002072 ! nodal myocyte relationship: results_in_acquisition_of_features_of CL:0002072 ! nodal myocyte created_by: dph creation_date: 2009-09-29T11:01:31Z [Term] id: GO:0060921 name: sinoatrial node cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell differentiation" EXACT [GOC:mtg_heart] synonym: "SAN cell differentiation" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node cell differentiation" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000409 ! myocyte of sinoatrial node relationship: part_of GO:0003163 ! sinoatrial node development relationship: results_in_acquisition_of_features_of CL:1000409 ! myocyte of sinoatrial node created_by: dph creation_date: 2009-09-29T11:03:30Z [Term] id: GO:0060922 name: atrioventricular node cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." [GOC:mtg_heart] synonym: "AV node cell differentiation" RELATED [GOC:mtg_heart] is_a: GO:0003292 ! cardiac septum cell differentiation is_a: GO:0060920 ! cardiac pacemaker cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000410 ! myocyte of atrioventricular node relationship: part_of GO:0003162 ! atrioventricular node development relationship: results_in_acquisition_of_features_of CL:1000410 ! myocyte of atrioventricular node created_by: dph creation_date: 2009-09-29T11:07:06Z [Term] id: GO:0060926 name: cardiac pacemaker cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." [GOC:mtg_cardiac_conduct_nov11, GOC:mtg_heart] synonym: "pacemaker cell development" BROAD [] is_a: GO:0055013 ! cardiac muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0002072 ! nodal myocyte relationship: part_of GO:0060920 ! cardiac pacemaker cell differentiation relationship: results_in_development_of CL:0002072 ! nodal myocyte created_by: dph creation_date: 2009-09-29T11:51:55Z [Term] id: GO:0060928 name: atrioventricular node cell development namespace: biological_process def: "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "AV node cell development" EXACT [GOC:mtg_heart] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:1000410 ! myocyte of atrioventricular node relationship: part_of GO:0060922 ! atrioventricular node cell differentiation relationship: results_in_development_of CL:1000410 ! myocyte of atrioventricular node created_by: dph creation_date: 2009-09-29T11:59:26Z [Term] id: GO:0060931 name: sinoatrial node cell development namespace: biological_process def: "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." [GOC:mtg_heart] synonym: "SA node cell development" EXACT [GOC:mtg_heart] synonym: "SAN cell development" EXACT [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "sinus node cell development" NARROW [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0060926 ! cardiac pacemaker cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:1000409 ! myocyte of sinoatrial node relationship: part_of GO:0060921 ! sinoatrial node cell differentiation relationship: results_in_development_of CL:1000409 ! myocyte of sinoatrial node created_by: dph creation_date: 2009-09-29T12:05:47Z [Term] id: GO:0060932 name: His-Purkinje system cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055007 ! cardiac muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010007 ! His-Purkinje system cell relationship: part_of GO:0003164 ! His-Purkinje system development relationship: results_in_acquisition_of_features_of CL:0010007 ! His-Purkinje system cell created_by: dph creation_date: 2009-09-29T01:10:32Z [Term] id: GO:0060933 name: His-Purkinje system cell development namespace: biological_process def: "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0010007 ! His-Purkinje system cell relationship: part_of GO:0060932 ! His-Purkinje system cell differentiation relationship: results_in_development_of CL:0010007 ! His-Purkinje system cell created_by: dph creation_date: 2009-09-29T01:15:02Z [Term] id: GO:0060935 name: cardiac fibroblast cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002548 ! fibroblast of cardiac tissue relationship: results_in_acquisition_of_features_of CL:0002548 ! fibroblast of cardiac tissue created_by: dph creation_date: 2009-09-29T01:20:04Z [Term] id: GO:0060936 name: cardiac fibroblast cell development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." [GOC:mtg_heart] is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0002548 ! fibroblast of cardiac tissue relationship: part_of GO:0060935 ! cardiac fibroblast cell differentiation relationship: results_in_development_of CL:0002548 ! fibroblast of cardiac tissue created_by: dph creation_date: 2009-09-29T01:23:03Z [Term] id: GO:0060945 name: cardiac neuron differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." [GOC:mtg_heart] synonym: "heart neuron differentiation" EXACT [GOC:mtg_heart] is_a: GO:0030182 ! neuron differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010022 ! cardiac neuron relationship: part_of GO:0048483 ! autonomic nervous system development relationship: results_in_acquisition_of_features_of CL:0010022 ! cardiac neuron created_by: dph creation_date: 2009-09-29T02:45:33Z [Term] id: GO:0060946 name: cardiac blood vessel endothelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation is_a: GO:0060837 ! blood vessel endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010006 ! cardiac blood vessel endothelial cell relationship: results_in_acquisition_of_features_of CL:0010006 ! cardiac blood vessel endothelial cell created_by: dph creation_date: 2009-09-29T02:48:55Z [Term] id: GO:0060950 name: cardiac glial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." [GOC:mtg_heart] is_a: GO:0010001 ! glial cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0010020 ! cardiac glial cell relationship: results_in_acquisition_of_features_of CL:0010020 ! cardiac glial cell created_by: dph creation_date: 2009-09-29T03:06:37Z [Term] id: GO:0060952 name: cardiac glial cell development namespace: biological_process def: "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." [GOC:mtg_heart] is_a: GO:0021782 ! glial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0010020 ! cardiac glial cell relationship: part_of GO:0060950 ! cardiac glial cell differentiation relationship: results_in_development_of CL:0010020 ! cardiac glial cell created_by: dph creation_date: 2009-09-29T03:09:24Z [Term] id: GO:0060956 name: endocardial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:mtg_heart] is_a: GO:0003348 ! cardiac endothelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002350 ! endocardial cell relationship: part_of GO:0003157 ! endocardium development relationship: results_in_acquisition_of_features_of CL:0002350 ! endocardial cell created_by: dph creation_date: 2009-09-29T03:20:39Z [Term] id: GO:0060958 name: endocardial cell development namespace: biological_process def: "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." [GOC:mtg_heart] is_a: GO:0001885 ! endothelial cell development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0002350 ! endocardial cell relationship: part_of GO:0060956 ! endocardial cell differentiation relationship: results_in_development_of CL:0002350 ! endocardial cell created_by: dph creation_date: 2009-09-29T03:26:59Z [Term] id: GO:0060959 name: cardiac neuron development namespace: biological_process def: "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." [GOC:mtg_heart] synonym: "heart neuron development" EXACT [GOC:mtg_heart] is_a: GO:0048666 ! neuron development is_a: GO:0055006 ! cardiac cell development intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0010022 ! cardiac neuron relationship: part_of GO:0060945 ! cardiac neuron differentiation relationship: results_in_development_of CL:0010022 ! cardiac neuron created_by: dph creation_date: 2009-09-30T10:14:56Z [Term] id: GO:0060973 name: cell migration involved in heart development namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." [GOC:mtg_heart] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0007507 ! heart development relationship: part_of GO:0007507 ! heart development created_by: dph creation_date: 2009-10-06T10:53:49Z [Term] id: GO:0060974 name: cell migration involved in heart formation namespace: biological_process def: "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060914 ! heart formation relationship: part_of GO:0060914 ! heart formation created_by: dph creation_date: 2009-10-06T10:56:33Z [Term] id: GO:0060976 name: coronary vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." [GOC:mtg_heart] synonym: "cardiac blood vessel development" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature development" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart blood vessel development" EXACT [GOC:mtg_heart] synonym: "heart vasculature development" EXACT [GOC:mtg_heart] is_a: GO:0001568 ! blood vessel development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003498 ! heart blood vessel relationship: part_of GO:0007507 ! heart development relationship: results_in_development_of UBERON:0003498 ! heart blood vessel created_by: dph creation_date: 2009-10-06T12:15:23Z [Term] id: GO:0060977 name: coronary vasculature morphogenesis namespace: biological_process def: "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." [GOC:mtg_heart] synonym: "cardiac blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "cardiac vasculature morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart blood vessel morphogenesis" EXACT [GOC:mtg_heart] synonym: "heart vasculature morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0048514 ! blood vessel morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003498 ! heart blood vessel relationship: part_of GO:0060976 ! coronary vasculature development relationship: results_in_morphogenesis_of UBERON:0003498 ! heart blood vessel created_by: dph creation_date: 2009-10-06T12:28:23Z [Term] id: GO:0060978 name: angiogenesis involved in coronary vascular morphogenesis namespace: biological_process def: "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." [GOC:mtg_heart] synonym: "angiogenesis involved in cardiac vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "angiogenesis involved in heart vascular morphogenesis" EXACT [GOC:mtg_heart] synonym: "coronary blood vessel angiogenesis" EXACT [GOC:mtg_heart] synonym: "coronary vasculature angiogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001525 ! angiogenesis intersection_of: GO:0001525 ! angiogenesis intersection_of: part_of GO:0060976 ! coronary vasculature development relationship: part_of GO:0060977 ! coronary vasculature morphogenesis created_by: dph creation_date: 2009-10-06T02:02:12Z [Term] id: GO:0060979 name: vasculogenesis involved in coronary vascular morphogenesis namespace: biological_process def: "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." [GOC:mtg_heart] synonym: "coronary vasculogenesis" EXACT [GOC:mtg_heart] synonym: "vasculogenesis involved in coronary blood vessel morphogenesis" EXACT [GOC:mtg_heart] is_a: GO:0001570 ! vasculogenesis intersection_of: GO:0001570 ! vasculogenesis intersection_of: part_of GO:0060977 ! coronary vasculature morphogenesis relationship: part_of GO:0060977 ! coronary vasculature morphogenesis created_by: dph creation_date: 2009-10-06T02:19:42Z [Term] id: GO:0060980 name: cell migration involved in coronary vasculogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." [GOC:mtg_heart] is_a: GO:0035441 ! cell migration involved in vasculogenesis is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis relationship: part_of GO:0060979 ! vasculogenesis involved in coronary vascular morphogenesis created_by: dph creation_date: 2009-10-06T02:33:06Z [Term] id: GO:0060981 name: cell migration involved in coronary angiogenesis namespace: biological_process def: "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." [GOC:mtg_heart] is_a: GO:0060973 ! cell migration involved in heart development intersection_of: GO:0016477 ! cell migration intersection_of: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis relationship: part_of GO:0060978 ! angiogenesis involved in coronary vascular morphogenesis created_by: dph creation_date: 2009-10-06T02:49:12Z [Term] id: GO:0060986 name: endocrine hormone secretion namespace: biological_process def: "The regulated release of a hormone into the circulatory system." [GOC:dph] is_a: GO:0046879 ! hormone secretion relationship: part_of GO:0050886 ! endocrine process created_by: dph creation_date: 2010-01-11T09:03:48Z [Term] id: GO:0060993 name: kidney morphogenesis namespace: biological_process def: "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002113 ! kidney relationship: part_of GO:0001822 ! kidney development relationship: results_in_morphogenesis_of UBERON:0002113 ! kidney created_by: dph creation_date: 2010-01-19T08:16:55Z [Term] id: GO:0060995 name: cell-cell signaling involved in kidney development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in kidney development" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: dph creation_date: 2010-01-19T08:33:40Z [Term] id: GO:0061004 name: pattern specification involved in kidney development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." [GOC:dph, GOC:mtg_kidney_jan10] synonym: "kidney pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney pattern specification" EXACT [GOC:mtg_kidney_jan10] synonym: "pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development relationship: part_of GO:0072048 ! renal system pattern specification created_by: dph creation_date: 2010-01-21T09:05:54Z [Term] id: GO:0061005 name: cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0030154 ! cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: dph creation_date: 2010-01-21T09:13:55Z [Term] id: GO:0061006 name: regulation of cell proliferation involved in kidney morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0042127 ! regulation of cell population proliferation intersection_of: part_of GO:0060993 ! kidney morphogenesis relationship: part_of GO:0060993 ! kidney morphogenesis created_by: dph creation_date: 2010-01-21T11:25:23Z [Term] id: GO:0061007 name: hepaticobiliary system process namespace: biological_process def: "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] subset: goslim_generic synonym: "hepatobiliary system process" EXACT [GOC:dph] is_a: GO:0003008 ! system process created_by: dph creation_date: 2010-01-22T09:09:10Z [Term] id: GO:0061008 name: hepaticobiliary system development namespace: biological_process def: "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." [GOC:dph] synonym: "hepatobiliary system development" EXACT [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002423 ! hepatobiliary system relationship: results_in_development_of UBERON:0002423 ! hepatobiliary system created_by: dph creation_date: 2010-01-22T09:11:59Z [Term] id: GO:0061009 name: common bile duct development namespace: biological_process def: "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine." [PMID:20614624] synonym: "bile duct development" EXACT [GOC:dph] synonym: "CBD development" EXACT [PMID:20614624] synonym: "EHBD development" BROAD [PMID:20614624] synonym: "extrahepatic bile duct development" BROAD [PMID:20614624] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002394 ! bile duct relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: results_in_development_of UBERON:0002394 ! bile duct created_by: dph creation_date: 2010-01-22T09:17:13Z [Term] id: GO:0061010 name: gallbladder development namespace: biological_process def: "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002110 ! gallbladder relationship: part_of GO:0061008 ! hepaticobiliary system development relationship: results_in_development_of UBERON:0002110 ! gallbladder created_by: dph creation_date: 2010-01-22T09:38:44Z [Term] id: GO:0061011 name: hepatic duct development namespace: biological_process def: "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." [GOC:dph, PMID:20614624] is_a: GO:0061009 ! common bile duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001175 ! common hepatic duct relationship: results_in_development_of UBERON:0001175 ! common hepatic duct created_by: dph creation_date: 2010-01-22T09:44:39Z [Term] id: GO:0061017 name: hepatoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." [GOC:dph, PMID:15226394] is_a: GO:0030855 ! epithelial cell differentiation is_a: GO:0048863 ! stem cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000488 ! cholangiocyte relationship: part_of GO:0001889 ! liver development relationship: results_in_acquisition_of_features_of CL:1000488 ! cholangiocyte created_by: dph creation_date: 2010-02-02T09:08:03Z [Term] id: GO:0061024 name: membrane organization namespace: biological_process alt_id: GO:0016044 alt_id: GO:0044802 def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." [GOC:dph, GOC:tb] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: prokaryote_subset synonym: "cellular membrane organisation" EXACT [] synonym: "cellular membrane organization" EXACT [] synonym: "membrane organisation" EXACT [GOC:mah] synonym: "membrane organization and biogenesis" RELATED [GOC:mah] synonym: "single-organism membrane organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0016020 ! membrane relationship: results_in_organization_of GO:0016020 ! membrane created_by: jl creation_date: 2010-02-08T02:43:11Z [Term] id: GO:0061025 name: membrane fusion namespace: biological_process alt_id: GO:0006944 alt_id: GO:0044801 def: "The membrane organization process that joins two lipid bilayers to form a single membrane." [GOC:dph, GOC:tb] subset: goslim_yeast synonym: "cellular membrane fusion" EXACT [] synonym: "single-organism membrane fusion" RELATED [] xref: Wikipedia:Lipid_bilayer_fusion is_a: GO:0061024 ! membrane organization intersection_of: GO:0061024 ! membrane organization intersection_of: results_in_fusion_of GO:0016020 ! membrane relationship: results_in_fusion_of GO:0016020 ! membrane created_by: jl creation_date: 2010-02-08T02:48:06Z [Term] id: GO:0061027 name: umbilical cord development namespace: biological_process def: "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." [GOC:BHF, GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002331 ! umbilical cord relationship: results_in_development_of UBERON:0002331 ! umbilical cord created_by: dph creation_date: 2010-02-09T09:09:22Z [Term] id: GO:0061032 name: visceral serous pericardium development namespace: biological_process def: "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." [GOC:dph, GOC:yaf] synonym: "epicardium development" EXACT [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002425 ! visceral serous pericardium relationship: part_of GO:0060039 ! pericardium development relationship: results_in_development_of UBERON:0002425 ! visceral serous pericardium created_by: dph creation_date: 2010-02-09T09:52:49Z [Term] id: GO:0061035 name: regulation of cartilage development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051216 ! cartilage development relationship: regulates GO:0051216 ! cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061036 name: positive regulation of cartilage development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051216 ! cartilage development relationship: positively_regulates GO:0051216 ! cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061037 name: negative regulation of cartilage development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." [GOC:dph] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061035 ! regulation of cartilage development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051216 ! cartilage development relationship: negatively_regulates GO:0051216 ! cartilage development created_by: dph creation_date: 2010-02-09T03:41:35Z [Term] id: GO:0061038 name: uterus morphogenesis namespace: biological_process def: "The process in which anatomical structures of the uterus are generated and organized." [GOC:BHF, GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000995 ! uterus relationship: part_of GO:0060065 ! uterus development relationship: results_in_morphogenesis_of UBERON:0000995 ! uterus created_by: dph creation_date: 2010-02-22T11:12:35Z [Term] id: GO:0061040 name: female gonad morphogenesis namespace: biological_process def: "The process in which a female gonad is generated and organized." [GOC:BHF, GOC:dph] synonym: "ovary morphogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0035262 ! gonad morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000992 ! ovary relationship: part_of GO:0008585 ! female gonad development relationship: results_in_morphogenesis_of UBERON:0000992 ! ovary created_by: dph creation_date: 2010-02-22T11:29:28Z [Term] id: GO:0061046 name: regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis relationship: regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:41:38Z [Term] id: GO:0061047 name: positive regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis relationship: positively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:50:01Z [Term] id: GO:0061048 name: negative regulation of branching involved in lung morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." [GOC:dph, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0061046 ! regulation of branching involved in lung morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis relationship: negatively_regulates GO:0060441 ! epithelial tube branching involved in lung morphogenesis created_by: dph creation_date: 2010-02-25T10:51:31Z [Term] id: GO:0061049 name: cell growth involved in cardiac muscle cell development namespace: biological_process def: "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] synonym: "cardiac muscle cell hypertrophy" RELATED [GOC:dph] synonym: "cardiomyocyte growth" RELATED [GOC:dph] synonym: "heart muscle cell growth" RELATED [GOC:dph] is_a: GO:0048588 ! developmental cell growth intersection_of: GO:0016049 ! cell growth intersection_of: part_of GO:0055013 ! cardiac muscle cell development relationship: part_of GO:0003301 ! physiological cardiac muscle hypertrophy relationship: part_of GO:0055013 ! cardiac muscle cell development created_by: dph creation_date: 2010-02-25T12:56:07Z [Term] id: GO:0061050 name: regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0001558 ! regulation of cell growth is_a: GO:0055021 ! regulation of cardiac muscle tissue growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development relationship: regulates GO:0061049 ! cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:05:16Z [Term] id: GO:0061051 name: positive regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010613 ! positive regulation of cardiac muscle hypertrophy is_a: GO:0030307 ! positive regulation of cell growth is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:0055023 ! positive regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development relationship: positively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:08:08Z [Term] id: GO:0061052 name: negative regulation of cell growth involved in cardiac muscle cell development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." [GOC:dph] is_a: GO:0010614 ! negative regulation of cardiac muscle hypertrophy is_a: GO:0030308 ! negative regulation of cell growth is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:0055022 ! negative regulation of cardiac muscle tissue growth is_a: GO:0061050 ! regulation of cell growth involved in cardiac muscle cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development relationship: negatively_regulates GO:0061049 ! cell growth involved in cardiac muscle cell development created_by: dph creation_date: 2010-02-25T01:11:30Z [Term] id: GO:0061053 name: somite development namespace: biological_process def: "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." [GOC:dph] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002329 ! somite relationship: part_of GO:0009790 ! embryo development relationship: results_in_development_of UBERON:0002329 ! somite created_by: dph creation_date: 2010-03-02T12:05:13Z [Term] id: GO:0061054 name: dermatome development namespace: biological_process def: "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004016 ! dermatome relationship: part_of GO:0061053 ! somite development relationship: results_in_development_of UBERON:0004016 ! dermatome created_by: dph creation_date: 2010-03-02T12:07:37Z [Term] id: GO:0061055 name: myotome development namespace: biological_process def: "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003082 ! myotome relationship: part_of GO:0061053 ! somite development relationship: results_in_development_of UBERON:0003082 ! myotome created_by: dph creation_date: 2010-03-02T12:11:01Z [Term] id: GO:0061056 name: sclerotome development namespace: biological_process def: "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003089 ! sclerotome relationship: part_of GO:0061053 ! somite development relationship: results_in_development_of UBERON:0003089 ! sclerotome created_by: dph creation_date: 2010-03-02T12:12:40Z [Term] id: GO:0061061 name: muscle structure development namespace: biological_process def: "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." [GOC:dph] subset: goslim_drosophila is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005090 ! muscle structure relationship: in_taxon NCBITaxon:6072 {all_only="true"} ! Eumetazoa relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: results_in_development_of UBERON:0005090 ! muscle structure created_by: dph creation_date: 2010-03-09T08:55:14Z [Term] id: GO:0061062 name: regulation of nematode larval development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048580 ! regulation of post-embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002119 ! nematode larval development relationship: regulates GO:0002119 ! nematode larval development created_by: dph creation_date: 2010-03-11T12:59:21Z [Term] id: GO:0061063 name: positive regulation of nematode larval development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048582 ! positive regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002119 ! nematode larval development relationship: positively_regulates GO:0002119 ! nematode larval development created_by: dph creation_date: 2010-03-11T01:03:34Z [Term] id: GO:0061064 name: negative regulation of nematode larval development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GOC:dph, GOC:kmv] is_a: GO:0048581 ! negative regulation of post-embryonic development is_a: GO:0061062 ! regulation of nematode larval development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002119 ! nematode larval development relationship: negatively_regulates GO:0002119 ! nematode larval development created_by: dph creation_date: 2010-03-11T01:04:39Z [Term] id: GO:0061068 name: urethra development namespace: biological_process def: "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." [GOC:dph] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000057 ! urethra relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0000057 ! urethra created_by: dph creation_date: 2010-03-12T08:24:52Z [Term] id: GO:0061069 name: male urethra development namespace: biological_process def: "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001333 ! male urethra relationship: results_in_development_of UBERON:0001333 ! male urethra created_by: dph creation_date: 2010-03-12T08:28:19Z [Term] id: GO:0061070 name: female urethra development namespace: biological_process def: "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." [GOC:dph] is_a: GO:0061068 ! urethra development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001334 ! female urethra relationship: results_in_development_of UBERON:0001334 ! female urethra created_by: dph creation_date: 2010-03-12T08:29:43Z [Term] id: GO:0061071 name: urethra epithelium development namespace: biological_process def: "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." [GOC:dph] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002325 ! epithelium of urethra relationship: part_of GO:0061068 ! urethra development relationship: results_in_development_of UBERON:0002325 ! epithelium of urethra created_by: dph creation_date: 2010-03-12T08:36:53Z [Term] id: GO:0061072 name: iris morphogenesis namespace: biological_process def: "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001769 ! iris relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0001769 ! iris created_by: dph creation_date: 2010-03-16T10:48:42Z [Term] id: GO:0061073 name: ciliary body morphogenesis namespace: biological_process def: "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001775 ! ciliary body relationship: part_of GO:0048593 ! camera-type eye morphogenesis relationship: results_in_morphogenesis_of UBERON:0001775 ! ciliary body created_by: dph creation_date: 2010-03-16T10:55:19Z [Term] id: GO:0061074 name: regulation of neural retina development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003407 ! neural retina development relationship: regulates GO:0003407 ! neural retina development created_by: dph creation_date: 2010-03-16T11:47:05Z [Term] id: GO:0061075 name: positive regulation of neural retina development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902868 ! positive regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003407 ! neural retina development relationship: positively_regulates GO:0003407 ! neural retina development created_by: dph creation_date: 2010-03-16T11:59:48Z [Term] id: GO:0061076 name: negative regulation of neural retina development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." [GOC:dph] is_a: GO:0061074 ! regulation of neural retina development is_a: GO:1902867 ! negative regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003407 ! neural retina development relationship: negatively_regulates GO:0003407 ! neural retina development created_by: dph creation_date: 2010-03-16T12:46:11Z [Term] id: GO:0061080 name: right horn of sinus venosus development namespace: biological_process def: "The progression of the right horn of the sinus venosus from its formation to the mature structure." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005092 ! right horn of sinus venosus relationship: part_of GO:0003235 ! sinus venosus development relationship: results_in_development_of UBERON:0005092 ! right horn of sinus venosus created_by: dph creation_date: 2010-04-08T02:45:10Z [Term] id: GO:0061100 name: lung neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." [GOC:dph, PMID:9126746] is_a: GO:0061101 ! neuroendocrine cell differentiation is_a: GO:0061140 ! lung secretory cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell relationship: results_in_acquisition_of_features_of CL:1000223 ! lung neuroendocrine cell created_by: dph creation_date: 2010-04-27T03:28:46Z [Term] id: GO:0061101 name: neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." [GOC:dph] is_a: GO:0030182 ! neuron differentiation is_a: GO:0060563 ! neuroepithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000165 ! neuroendocrine cell relationship: results_in_acquisition_of_features_of CL:0000165 ! neuroendocrine cell created_by: dph creation_date: 2010-04-28T09:42:20Z [Term] id: GO:0061102 name: stomach neuroendocrine cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." [GOC:dph, PMID:18173746] synonym: "gastric neuroendocrine cell differentiation" RELATED [GOC:dph] is_a: GO:0035883 ! enteroendocrine cell differentiation is_a: GO:0061101 ! neuroendocrine cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000222 ! stomach neuroendocrine cell relationship: part_of GO:0062094 ! stomach development relationship: results_in_acquisition_of_features_of CL:1000222 ! stomach neuroendocrine cell created_by: dph creation_date: 2010-04-28T09:47:07Z [Term] id: GO:0061105 name: regulation of stomach neuroendocrine cell differentiation namespace: biological_process def: "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061102 ! stomach neuroendocrine cell differentiation relationship: regulates GO:0061102 ! stomach neuroendocrine cell differentiation created_by: dph creation_date: 2010-04-29T12:19:37Z [Term] id: GO:0061106 name: negative regulation of stomach neuroendocrine cell differentiation namespace: biological_process def: "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." [GOC:dph] is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:0061105 ! regulation of stomach neuroendocrine cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation relationship: negatively_regulates GO:0061102 ! stomach neuroendocrine cell differentiation created_by: dph creation_date: 2010-04-29T12:23:05Z [Term] id: GO:0061107 name: seminal vesicle development namespace: biological_process def: "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." [GOC:dph] is_a: GO:0048608 ! reproductive structure development is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000998 ! seminal vesicle relationship: results_in_development_of UBERON:0000998 ! seminal vesicle created_by: dph creation_date: 2010-04-30T10:17:30Z [Term] id: GO:0061108 name: seminal vesicle epithelium development namespace: biological_process def: "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004805 ! seminal vesicle epithelium relationship: part_of GO:0061107 ! seminal vesicle development relationship: results_in_development_of UBERON:0004805 ! seminal vesicle epithelium created_by: dph creation_date: 2010-04-30T10:19:54Z [Term] id: GO:0061113 name: pancreas morphogenesis namespace: biological_process def: "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." [GOC:dph] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001264 ! pancreas relationship: part_of GO:0031016 ! pancreas development relationship: results_in_morphogenesis_of UBERON:0001264 ! pancreas created_by: dph creation_date: 2010-05-05T11:55:30Z [Term] id: GO:0061114 name: branching involved in pancreas morphogenesis namespace: biological_process def: "The process in which the branches of the pancreas are generated and organized." [GOC:dph] is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0061113 ! pancreas morphogenesis relationship: part_of GO:0061113 ! pancreas morphogenesis created_by: dph creation_date: 2010-05-05T12:03:04Z [Term] id: GO:0061117 name: negative regulation of heart growth namespace: biological_process def: "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." [GOC:dph, GOC:hjd] is_a: GO:0046621 ! negative regulation of organ growth is_a: GO:0060420 ! regulation of heart growth intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060419 ! heart growth relationship: negatively_regulates GO:0060419 ! heart growth created_by: dph creation_date: 2010-05-17T07:31:28Z [Term] id: GO:0061130 name: pancreatic bud formation namespace: biological_process def: "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." [GOC:dph] is_a: GO:0048645 ! animal organ formation is_a: GO:0061114 ! branching involved in pancreas morphogenesis is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003922 ! pancreatic epithelial bud relationship: results_in_formation_of UBERON:0003922 ! pancreatic epithelial bud created_by: dph creation_date: 2010-05-17T09:33:40Z [Term] id: GO:0061138 name: morphogenesis of a branching epithelium namespace: biological_process def: "The process in which the anatomical structures of a branched epithelium are generated and organized." [GOC:dph] is_a: GO:0001763 ! morphogenesis of a branching structure is_a: GO:0002009 ! morphogenesis of an epithelium created_by: dph creation_date: 2010-05-25T09:05:34Z [Term] id: GO:0061140 name: lung secretory cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." [GOC:dph] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000272 ! lung secretory cell relationship: results_in_acquisition_of_features_of CL:1000272 ! lung secretory cell created_by: dph creation_date: 2010-05-25T09:28:53Z [Term] id: GO:0061141 name: lung ciliated cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." [GOC:cilia, GOC:dph, GOC:krc] is_a: GO:0060487 ! lung epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell relationship: results_in_acquisition_of_features_of CL:1000271 ! lung ciliated cell created_by: dph creation_date: 2010-05-25T09:31:14Z [Term] id: GO:0061147 name: endocardial endothelium development namespace: biological_process def: "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] is_a: GO:0003158 ! endothelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005316 ! endocardial endothelium relationship: part_of GO:0003157 ! endocardium development relationship: results_in_development_of UBERON:0005316 ! endocardial endothelium created_by: dph creation_date: 2010-06-03T09:15:31Z [Term] id: GO:0061148 name: extracellular matrix organization involved in endocardium development namespace: biological_process def: "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." [GOC:dph] synonym: "extracellular matrix organisation involved in endocardium development" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0030198 ! extracellular matrix organization intersection_of: part_of GO:0003157 ! endocardium development relationship: part_of GO:0003157 ! endocardium development created_by: dph creation_date: 2010-06-03T09:18:02Z [Term] id: GO:0061152 name: trachea submucosa development namespace: biological_process def: "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea." [GOC:dph, GOC:yaf] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002202 ! submucosa of trachea relationship: part_of GO:0060438 ! trachea development relationship: results_in_development_of UBERON:0002202 ! submucosa of trachea created_by: dph creation_date: 2010-06-07T09:58:40Z [Term] id: GO:0061153 name: trachea gland development namespace: biological_process def: "The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection." [GOC:dph] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005203 ! trachea gland relationship: part_of GO:0061152 ! trachea submucosa development relationship: results_in_development_of UBERON:0005203 ! trachea gland created_by: dph creation_date: 2010-06-07T10:10:51Z [Term] id: GO:0061154 name: endothelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." [GOC:dph, GOC:yaf] is_a: GO:0003159 ! morphogenesis of an endothelium is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003915 ! endothelial tube relationship: results_in_morphogenesis_of UBERON:0003915 ! endothelial tube created_by: dph creation_date: 2010-06-15T09:05:00Z [Term] id: GO:0061155 name: pulmonary artery endothelial tube morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." [GOC:dph, GOC:yaf] is_a: GO:0061154 ! endothelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005317 ! pulmonary artery endothelium relationship: part_of GO:0061156 ! pulmonary artery morphogenesis relationship: results_in_morphogenesis_of UBERON:0005317 ! pulmonary artery endothelium created_by: dph creation_date: 2010-06-15T09:09:04Z [Term] id: GO:0061156 name: pulmonary artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." [GOC:dph, GOC:yaf] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002012 ! pulmonary artery relationship: results_in_morphogenesis_of UBERON:0002012 ! pulmonary artery created_by: dph creation_date: 2010-06-15T09:13:47Z [Term] id: GO:0061181 name: regulation of chondrocyte development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002063 ! chondrocyte development relationship: regulates GO:0002063 ! chondrocyte development created_by: dph creation_date: 2010-07-14T08:28:52Z [Term] id: GO:0061182 name: negative regulation of chondrocyte development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." [GOC:BHF, GOC:dph] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0032331 ! negative regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002063 ! chondrocyte development relationship: negatively_regulates GO:0002063 ! chondrocyte development created_by: dph creation_date: 2010-07-14T08:33:05Z [Term] id: GO:0061183 name: regulation of dermatome development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061054 ! dermatome development relationship: regulates GO:0061054 ! dermatome development created_by: dph creation_date: 2010-07-14T08:40:26Z [Term] id: GO:0061184 name: positive regulation of dermatome development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0040019 ! positive regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061054 ! dermatome development relationship: positively_regulates GO:0061054 ! dermatome development created_by: dph creation_date: 2010-07-14T08:42:03Z [Term] id: GO:0061185 name: negative regulation of dermatome development namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." [GOC:BHF, GOC:dph] is_a: GO:0045992 ! negative regulation of embryonic development is_a: GO:0061183 ! regulation of dermatome development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061054 ! dermatome development relationship: negatively_regulates GO:0061054 ! dermatome development created_by: dph creation_date: 2010-07-14T08:43:08Z [Term] id: GO:0061189 name: positive regulation of sclerotome development namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:BHF, GOC:dph] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0061190 ! regulation of sclerotome development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061056 ! sclerotome development relationship: positively_regulates GO:0061056 ! sclerotome development created_by: dph creation_date: 2010-07-14T09:17:23Z [Term] id: GO:0061190 name: regulation of sclerotome development namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." [GOC:dph] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061056 ! sclerotome development relationship: regulates GO:0061056 ! sclerotome development created_by: dph creation_date: 2010-07-14T09:19:47Z [Term] id: GO:0061193 name: taste bud development namespace: biological_process def: "The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] is_a: GO:0007423 ! sensory organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001727 ! taste bud relationship: part_of GO:0043586 ! tongue development relationship: results_in_development_of UBERON:0001727 ! taste bud created_by: dph creation_date: 2010-07-27T10:55:08Z [Term] id: GO:0061194 name: taste bud morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] is_a: GO:0090596 ! sensory organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001727 ! taste bud relationship: part_of GO:0043587 ! tongue morphogenesis relationship: part_of GO:0061193 ! taste bud development relationship: results_in_morphogenesis_of UBERON:0001727 ! taste bud created_by: dph creation_date: 2010-07-27T11:01:31Z [Term] id: GO:0061195 name: taste bud formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors." [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001727 ! taste bud relationship: part_of GO:0061194 ! taste bud morphogenesis relationship: results_in_formation_of UBERON:0001727 ! taste bud created_by: dph creation_date: 2010-07-27T12:22:26Z [Term] id: GO:0061205 name: paramesonephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." [GOC:dph, GOC:yaf] synonym: "Mullerian duct development" EXACT [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003890 ! Mullerian duct relationship: results_in_development_of UBERON:0003890 ! Mullerian duct created_by: dph creation_date: 2010-07-30T10:54:47Z [Term] id: GO:0061206 name: mesonephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephros are generated and organized." [GOC:mtg_kidney_jan10] synonym: "Wolffian body morphogenesis" EXACT [GOC:dph] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000080 ! mesonephros relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_morphogenesis_of UBERON:0000080 ! mesonephros created_by: dph creation_date: 2010-08-17T03:11:10Z [Term] id: GO:0061208 name: cell differentiation involved in mesonephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:21:23Z [Term] id: GO:0061209 name: cell proliferation involved in mesonephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:22:46Z [Term] id: GO:0061210 name: cell-cell signaling involved in mesonephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in mesonephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:24:08Z [Term] id: GO:0061211 name: mesonephric collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005319 ! mesonephric collecting duct relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005319 ! mesonephric collecting duct created_by: dph creation_date: 2010-08-17T03:25:51Z [Term] id: GO:0061213 name: positive regulation of mesonephros development namespace: biological_process def: "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001823 ! mesonephros development relationship: positively_regulates GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:39:35Z [Term] id: GO:0061214 name: mesonephric smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005321 ! mesonephric smooth muscle tissue relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005321 ! mesonephric smooth muscle tissue created_by: dph creation_date: 2010-08-17T03:29:54Z [Term] id: GO:0061215 name: mesonephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005322 ! mesonephric nephron relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005322 ! mesonephric nephron created_by: dph creation_date: 2010-08-17T03:31:08Z [Term] id: GO:0061217 name: regulation of mesonephros development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001823 ! mesonephros development relationship: regulates GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:35:31Z [Term] id: GO:0061218 name: negative regulation of mesonephros development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001823 ! mesonephros development relationship: negatively_regulates GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-17T03:43:06Z [Term] id: GO:0061219 name: mesonephric mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005323 ! mesonephric mesenchyme relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005323 ! mesonephric mesenchyme created_by: dph creation_date: 2010-08-17T03:45:44Z [Term] id: GO:0061221 name: mesonephric mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005323 ! mesonephric mesenchyme relationship: part_of GO:0061219 ! mesonephric mesenchyme development relationship: results_in_morphogenesis_of UBERON:0005323 ! mesonephric mesenchyme created_by: dph creation_date: 2010-08-19T01:17:38Z [Term] id: GO:0061227 name: pattern specification involved in mesonephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "mesonephros pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "mesonephros pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001823 ! mesonephros development relationship: part_of GO:0001823 ! mesonephros development created_by: dph creation_date: 2010-08-19T02:22:22Z [Term] id: GO:0061228 name: mesonephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005322 ! mesonephric nephron relationship: part_of GO:0061206 ! mesonephros morphogenesis relationship: part_of GO:0061215 ! mesonephric nephron development relationship: results_in_morphogenesis_of UBERON:0005322 ! mesonephric nephron created_by: dph creation_date: 2010-08-19T02:26:24Z [Term] id: GO:0061235 name: mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis created_by: dph creation_date: 2010-08-19T02:57:11Z [Term] id: GO:0061241 name: mesonephric nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005330 ! mesonephric nephron epithelium relationship: part_of GO:0061215 ! mesonephric nephron development relationship: results_in_development_of UBERON:0005330 ! mesonephric nephron epithelium created_by: dph creation_date: 2010-08-19T03:11:59Z [Term] id: GO:0061243 name: mesonephric renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005331 ! mesonephric renal vesicle relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0005331 ! mesonephric renal vesicle created_by: dph creation_date: 2010-08-19T03:20:21Z [Term] id: GO:0061261 name: mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." [GOC:mtg_kidney_jan10] synonym: "mesonephric mesenchyme to epithelial transition" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition is_a: GO:0061208 ! cell differentiation involved in mesonephros development intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0061206 ! mesonephros morphogenesis relationship: part_of GO:0061206 ! mesonephros morphogenesis created_by: dph creation_date: 2010-08-30T02:35:15Z [Term] id: GO:0061262 name: mesonephric renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the mesonephros." [GOC:mtg_kidney_jan10] synonym: "mesonephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005331 ! mesonephric renal vesicle relationship: part_of GO:0061243 ! mesonephric renal vesicle morphogenesis relationship: results_in_formation_of UBERON:0005331 ! mesonephric renal vesicle created_by: dph creation_date: 2010-08-30T02:41:20Z [Term] id: GO:0061271 name: mesenchymal to epithelial transition involved in mesonephric renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0061262 ! mesonephric renal vesicle formation relationship: part_of GO:0061262 ! mesonephric renal vesicle formation created_by: dph creation_date: 2010-08-30T03:26:30Z [Term] id: GO:0061285 name: mesonephric capsule development namespace: biological_process def: "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006170 ! mesonephric capsule relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0006170 ! mesonephric capsule created_by: dph creation_date: 2010-09-02T01:50:06Z [Term] id: GO:0061286 name: mesonephric capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0006170 ! mesonephric capsule relationship: part_of GO:0061285 ! mesonephric capsule development relationship: results_in_morphogenesis_of UBERON:0006170 ! mesonephric capsule created_by: dph creation_date: 2010-09-02T01:53:31Z [Term] id: GO:0061287 name: mesonephric capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0006170 ! mesonephric capsule relationship: part_of GO:0061286 ! mesonephric capsule morphogenesis relationship: results_in_formation_of UBERON:0006170 ! mesonephric capsule created_by: dph creation_date: 2010-09-02T01:55:03Z [Term] id: GO:0061295 name: regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:48:56Z [Term] id: GO:0061296 name: negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061218 ! negative regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: negatively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: negatively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:54:49Z [Term] id: GO:0061297 name: positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" EXACT [] is_a: GO:0061213 ! positive regulation of mesonephros development is_a: GO:0061295 ! regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis relationship: positively_regulates GO:0061235 ! mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis relationship: positively_regulates GO:1901146 ! mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis created_by: dph creation_date: 2010-09-06T09:58:59Z [Term] id: GO:0061298 name: retina vasculature development in camera-type eye namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] synonym: "retinal vasculature development" EXACT [GOC:dph] is_a: GO:0001944 ! vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004864 ! vasculature of retina relationship: part_of GO:0060041 ! retina development in camera-type eye relationship: results_in_development_of UBERON:0004864 ! vasculature of retina created_by: dph creation_date: 2010-09-06T03:27:06Z [Term] id: GO:0061299 name: retina vasculature morphogenesis in camera-type eye namespace: biological_process def: "The process in which the vasculature of the retina is generated and organized." [GOC:BHF, GOC:dph] synonym: "retinal vasculature morphogenesis" EXACT [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004864 ! vasculature of retina relationship: part_of GO:0061298 ! retina vasculature development in camera-type eye relationship: results_in_morphogenesis_of UBERON:0004864 ! vasculature of retina created_by: dph creation_date: 2010-09-06T03:28:25Z [Term] id: GO:0061303 name: cornea development in camera-type eye namespace: biological_process def: "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." [GOC:dph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000964 ! cornea relationship: part_of GO:0043010 ! camera-type eye development relationship: results_in_development_of UBERON:0000964 ! cornea created_by: dph creation_date: 2010-09-14T02:09:08Z [Term] id: GO:0061304 name: retinal blood vessel morphogenesis namespace: biological_process def: "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." [GOC:BHF, GOC:dph] is_a: GO:0048514 ! blood vessel morphogenesis is_a: GO:0061299 ! retina vasculature morphogenesis in camera-type eye intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003501 ! retina blood vessel relationship: results_in_morphogenesis_of UBERON:0003501 ! retina blood vessel created_by: dph creation_date: 2010-09-16T09:02:59Z [Term] id: GO:0061307 name: cardiac neural crest cell differentiation involved in heart development namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." [GOC:dph, GOC:mtg_heart, PMID:19705442] is_a: GO:0014033 ! neural crest cell differentiation is_a: GO:0035051 ! cardiocyte differentiation intersection_of: GO:0014033 ! neural crest cell differentiation intersection_of: part_of GO:0007507 ! heart development created_by: dph creation_date: 2010-09-23T08:50:56Z [Term] id: GO:0061308 name: cardiac neural crest cell development involved in heart development namespace: biological_process def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0014032 ! neural crest cell development intersection_of: GO:0014032 ! neural crest cell development intersection_of: part_of GO:0007507 ! heart development relationship: part_of GO:0061307 ! cardiac neural crest cell differentiation involved in heart development created_by: dph creation_date: 2010-09-23T09:01:49Z [Term] id: GO:0061309 name: cardiac neural crest cell development involved in outflow tract morphogenesis namespace: biological_process def: "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061308 ! cardiac neural crest cell development involved in heart development intersection_of: GO:0014032 ! neural crest cell development intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2010-09-23T09:08:37Z [Term] id: GO:0061323 name: cell proliferation involved in heart morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2010-09-28T09:05:26Z [Term] id: GO:0061325 name: cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." [GOC:dph, GOC:mtg_heart] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003151 ! outflow tract morphogenesis relationship: part_of GO:0003151 ! outflow tract morphogenesis created_by: dph creation_date: 2010-09-28T09:29:30Z [Term] id: GO:0061326 name: renal tubule development namespace: biological_process def: "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009773 ! renal tubule relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0009773 ! renal tubule created_by: dph creation_date: 2010-09-28T12:50:43Z [Term] id: GO:0061333 name: renal tubule morphogenesis namespace: biological_process def: "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0009773 ! renal tubule relationship: part_of GO:0061326 ! renal tubule development relationship: results_in_morphogenesis_of UBERON:0009773 ! renal tubule created_by: dph creation_date: 2010-09-28T01:43:04Z [Term] id: GO:0061337 name: cardiac conduction namespace: biological_process def: "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." [GOC:dph] is_a: GO:0008016 ! regulation of heart contraction created_by: dph creation_date: 2010-09-29T08:46:05Z [Term] id: GO:0061343 name: cell adhesion involved in heart morphogenesis namespace: biological_process def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0007155 ! cell adhesion intersection_of: GO:0007155 ! cell adhesion intersection_of: part_of GO:0003007 ! heart morphogenesis relationship: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2010-09-29T11:34:06Z [Term] id: GO:0061344 name: regulation of cell adhesion involved in heart morphogenesis namespace: biological_process def: "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." [GOC:dph, GOC:mtg_heart, PMID:16860783] is_a: GO:0030155 ! regulation of cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis relationship: regulates GO:0061343 ! cell adhesion involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T11:35:27Z [Term] id: GO:0061351 name: neural precursor cell proliferation namespace: biological_process def: "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." [GOC:dph, GOC:yaf] is_a: GO:0008283 ! cell population proliferation created_by: dph creation_date: 2010-10-01T11:06:04Z [Term] id: GO:0061383 name: trabecula morphogenesis namespace: biological_process def: "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000440 ! trabecula relationship: results_in_morphogenesis_of UBERON:0000440 ! trabecula created_by: dph creation_date: 2010-12-02T08:51:45Z [Term] id: GO:0061384 name: heart trabecula morphogenesis namespace: biological_process def: "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue." [GOC:dph] is_a: GO:0061383 ! trabecula morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002511 ! trabecula carnea relationship: results_in_morphogenesis_of UBERON:0002511 ! trabecula carnea created_by: dph creation_date: 2010-12-02T08:54:20Z [Term] id: GO:0061385 name: fibroblast proliferation involved in heart morphogenesis namespace: biological_process def: "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." [GOC:dph] is_a: GO:0048144 ! fibroblast proliferation is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0048144 ! fibroblast proliferation intersection_of: part_of GO:0003007 ! heart morphogenesis created_by: dph creation_date: 2011-02-10T01:41:59Z [Term] id: GO:0061437 name: renal system vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0001944 ! vasculature development relationship: part_of GO:0072001 ! renal system development created_by: dph creation_date: 2012-03-08T12:16:24Z [Term] id: GO:0061438 name: renal system vasculature morphogenesis namespace: biological_process def: "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0009653 ! anatomical structure morphogenesis relationship: part_of GO:0061437 ! renal system vasculature development created_by: dph creation_date: 2012-03-08T12:21:56Z [Term] id: GO:0061439 name: kidney vasculature morphogenesis namespace: biological_process def: "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." [GOC:dph, GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0006544 ! kidney vasculature relationship: part_of GO:0061438 ! renal system vasculature morphogenesis relationship: part_of GO:0061440 ! kidney vasculature development relationship: results_in_morphogenesis_of UBERON:0006544 ! kidney vasculature created_by: dph creation_date: 2012-03-08T12:30:11Z [Term] id: GO:0061440 name: kidney vasculature development namespace: biological_process def: "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." [GOC:dph, GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0061437 ! renal system vasculature development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006544 ! kidney vasculature relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0006544 ! kidney vasculature created_by: dph creation_date: 2012-03-08T12:39:09Z [Term] id: GO:0061441 name: renal artery morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." [GOC:mtg_kidney_jan10, PMID:11891195] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001184 ! renal artery relationship: part_of GO:0061439 ! kidney vasculature morphogenesis relationship: results_in_morphogenesis_of UBERON:0001184 ! renal artery created_by: dph creation_date: 2012-03-08T12:42:09Z [Term] id: GO:0061448 name: connective tissue development namespace: biological_process def: "The progression of a connective tissue over time, from its formation to the mature structure." [GOC:BHF] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002384 ! connective tissue relationship: results_in_development_of UBERON:0002384 ! connective tissue created_by: dph creation_date: 2012-03-22T12:53:41Z [Term] id: GO:0061450 name: trophoblast cell migration namespace: biological_process def: "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." [GOC:dph] is_a: GO:0001667 ! ameboidal-type cell migration is_a: GO:0022414 ! reproductive process intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000351 ! trophoblast cell relationship: part_of GO:0007566 ! embryo implantation relationship: results_in_movement_of CL:0000351 ! trophoblast cell created_by: dph creation_date: 2012-07-10T08:38:37Z [Term] id: GO:0061453 name: interstitial cell of Cajal differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." [GOC:dph] synonym: "ICC differentiation" RELATED [GOC:dph] is_a: GO:0060563 ! neuroepithelial cell differentiation is_a: GO:0060575 ! intestinal epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0002088 ! interstitial cell of Cajal relationship: results_in_acquisition_of_features_of CL:0002088 ! interstitial cell of Cajal created_by: dph creation_date: 2012-07-20T08:20:50Z [Term] id: GO:0061458 name: reproductive system development namespace: biological_process def: "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." [GOC:dph] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000990 ! reproductive system relationship: results_in_development_of UBERON:0000990 ! reproductive system created_by: dph creation_date: 2012-08-22T17:47:53Z [Term] id: GO:0061469 name: regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." [GOC:dph] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044342 ! type B pancreatic cell proliferation relationship: regulates GO:0044342 ! type B pancreatic cell proliferation created_by: dph creation_date: 2012-11-01T13:16:23Z [Term] id: GO:0061484 name: hematopoietic stem cell homeostasis namespace: biological_process def: "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." [GOC:dph, PMID:21508411] is_a: GO:0048872 ! homeostasis of number of cells intersection_of: GO:0048872 ! homeostasis of number of cells intersection_of: acts_on_population_of CL:0000037 ! hematopoietic stem cell relationship: acts_on_population_of CL:0000037 ! hematopoietic stem cell created_by: dph creation_date: 2012-12-04T09:41:02Z [Term] id: GO:0061512 name: protein localization to cilium namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cilium." [GOC:dph] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005929 ! cilium relationship: has_target_end_location GO:0005929 ! cilium relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota property_value: RO:0002161 NCBITaxon:3176 property_value: RO:0002161 NCBITaxon:3312 property_value: RO:0002161 NCBITaxon:3378 property_value: RO:0002161 NCBITaxon:3398 property_value: RO:0002161 NCBITaxon:4890 property_value: RO:0002161 NCBITaxon:5782 created_by: dph creation_date: 2013-03-22T15:41:44Z [Term] id: GO:0061515 name: myeloid cell development namespace: biological_process def: "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." [GOC:dph] is_a: GO:0030097 ! hemopoiesis intersection_of: GO:0048468 ! cell development intersection_of: results_in_development_of CL:0000763 ! myeloid cell relationship: part_of GO:0030099 ! myeloid cell differentiation relationship: results_in_development_of CL:0000763 ! myeloid cell created_by: dph creation_date: 2013-04-18T13:03:16Z [Term] id: GO:0061523 name: cilium disassembly namespace: biological_process def: "A cellular process that results in the breakdown of a cilium." [GOC:cilia, GOC:dph, PMID:17604723, PMID:27350441] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. synonym: "cilium resorption" EXACT [GOC:dph] is_a: GO:0044782 ! cilium organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005929 ! cilium relationship: results_in_disassembly_of GO:0005929 ! cilium created_by: dph creation_date: 2013-04-18T14:59:59Z [Term] id: GO:0061525 name: hindgut development namespace: biological_process def: "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." [GOC:dph] is_a: GO:0048565 ! digestive tract development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001046 ! hindgut relationship: results_in_development_of UBERON:0001046 ! hindgut created_by: dph creation_date: 2013-06-14T11:22:21Z [Term] id: GO:0061526 name: acetylcholine secretion namespace: biological_process def: "The regulated release of acetylcholine by a cell." [GOC:dph] is_a: GO:0015870 ! acetylcholine transport is_a: GO:0023061 ! signal release intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:15355 ! acetylcholine created_by: dph creation_date: 2013-06-21T15:40:39Z [Term] id: GO:0061533 name: norepinephrine secretion, neurotransmission namespace: biological_process def: "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." [GOC:dph] synonym: "noradrenaline secretion, neurotransmission" EXACT [GOC:dph] is_a: GO:0048243 ! norepinephrine secretion is_a: GO:0160043 ! catecholamine secretion, neurotransmission intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: has_primary_input CHEBI:72587 ! (R)-noradrenaline(1+) created_by: dph creation_date: 2013-06-21T16:05:08Z [Term] id: GO:0061548 name: ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "ganglia development" RELATED [GOC:dph] synonym: "gangliogenesis" NARROW [GOC:BHF, GOC:rl] is_a: GO:0009888 ! tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000045 ! ganglion relationship: part_of GO:0007399 ! nervous system development relationship: results_in_development_of UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:36:12Z [Term] id: GO:0061549 name: sympathetic ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." [GOC:BHF, GOC:rl] synonym: "sympathetic ganglia development" RELATED [GOC:dph] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001806 ! sympathetic ganglion relationship: part_of GO:0048485 ! sympathetic nervous system development relationship: results_in_development_of UBERON:0001806 ! sympathetic ganglion created_by: dph creation_date: 2013-07-10T08:38:01Z [Term] id: GO:0061550 name: cranial ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "cranial ganglia development" RELATED [GOC:dph] is_a: GO:0061548 ! ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001714 ! cranial ganglion relationship: part_of GO:0021545 ! cranial nerve development relationship: results_in_development_of UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T08:40:14Z [Term] id: GO:0061551 name: trigeminal ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." [GOC:dph] synonym: "trigeminal ganglia development" RELATED [GOC:dph] is_a: GO:0061550 ! cranial ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001675 ! trigeminal ganglion relationship: results_in_development_of UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:42:19Z [Term] id: GO:0061552 name: ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structures of ganglion are generated and organized." [GOC:dph] synonym: "ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000045 ! ganglion relationship: part_of GO:0061548 ! ganglion development relationship: results_in_morphogenesis_of UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:44:57Z [Term] id: GO:0061553 name: ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." [GOC:dph] synonym: "ganglia maturation" RELATED [GOC:dph] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0000045 ! ganglion relationship: part_of GO:0061548 ! ganglion development relationship: results_in_maturation_of UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:45:59Z [Term] id: GO:0061554 name: ganglion formation namespace: biological_process def: "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "ganglia formation" RELATED [GOC:dph] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000045 ! ganglion relationship: part_of GO:0061552 ! ganglion morphogenesis relationship: results_in_formation_of UBERON:0000045 ! ganglion created_by: dph creation_date: 2013-07-10T08:51:50Z [Term] id: GO:0061556 name: trigeminal ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." [GOC:dph] synonym: "trigeminal ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0061559 ! cranial ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001675 ! trigeminal ganglion relationship: part_of GO:0021636 ! trigeminal nerve morphogenesis relationship: part_of GO:0061551 ! trigeminal ganglion development relationship: results_in_morphogenesis_of UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:57:12Z [Term] id: GO:0061557 name: trigeminal ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." [GOC:dph] synonym: "trigeminal ganglia maturation" RELATED [GOC:dph] is_a: GO:0061558 ! cranial ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0001675 ! trigeminal ganglion relationship: part_of GO:0021635 ! trigeminal nerve maturation relationship: part_of GO:0061551 ! trigeminal ganglion development relationship: results_in_maturation_of UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T08:58:24Z [Term] id: GO:0061558 name: cranial ganglion maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." [GOC:dph] synonym: "cranial ganglia maturation" RELATED [GOC:dph] is_a: GO:0061553 ! ganglion maturation intersection_of: GO:0071695 ! anatomical structure maturation intersection_of: results_in_maturation_of UBERON:0001714 ! cranial ganglion relationship: part_of GO:0021605 ! cranial nerve maturation relationship: part_of GO:0061550 ! cranial ganglion development relationship: results_in_maturation_of UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T08:59:52Z [Term] id: GO:0061559 name: cranial ganglion morphogenesis namespace: biological_process def: "The process in which the anatomical structure of a cranial ganglion is generated and organized." [GOC:dph] synonym: "cranial ganglia morphogenesis" RELATED [GOC:dph] is_a: GO:0061552 ! ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001714 ! cranial ganglion relationship: part_of GO:0021602 ! cranial nerve morphogenesis relationship: part_of GO:0061550 ! cranial ganglion development relationship: results_in_morphogenesis_of UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T09:02:15Z [Term] id: GO:0061560 name: cranial ganglion formation namespace: biological_process def: "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "cranial ganglia formation" RELATED [GOC:dph] is_a: GO:0061554 ! ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001714 ! cranial ganglion relationship: part_of GO:0061559 ! cranial ganglion morphogenesis relationship: results_in_formation_of UBERON:0001714 ! cranial ganglion created_by: dph creation_date: 2013-07-10T09:07:27Z [Term] id: GO:0061561 name: trigeminal ganglion formation namespace: biological_process def: "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." [GOC:dph] synonym: "trigeminal ganglia formation" RELATED [GOC:dph] is_a: GO:0061560 ! cranial ganglion formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001675 ! trigeminal ganglion relationship: part_of GO:0061556 ! trigeminal ganglion morphogenesis relationship: results_in_formation_of UBERON:0001675 ! trigeminal ganglion created_by: dph creation_date: 2013-07-10T09:08:13Z [Term] id: GO:0061564 name: axon development namespace: biological_process def: "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." [GOC:dph, GOC:pg, GOC:pr] is_a: GO:0031175 ! neuron projection development created_by: dph creation_date: 2013-07-18T14:43:01Z [Term] id: GO:0061572 name: actin filament bundle organization namespace: biological_process def: "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." [GOC:dph] synonym: "actin filament cable organization" RELATED [GOC:dph] is_a: GO:0007015 ! actin filament organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0032432 ! actin filament bundle relationship: results_in_organization_of GO:0032432 ! actin filament bundle created_by: dph creation_date: 2013-08-02T11:24:11Z [Term] id: GO:0061580 name: colon epithelial cell migration namespace: biological_process def: "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0061582 ! intestinal epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0011108 ! colon epithelial cell relationship: results_in_movement_of CL:0011108 ! colon epithelial cell created_by: dph creation_date: 2013-12-23T07:26:54Z [Term] id: GO:0061581 name: corneal epithelial cell migration namespace: biological_process def: "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000575 ! corneal epithelial cell relationship: results_in_movement_of CL:0000575 ! corneal epithelial cell created_by: dph creation_date: 2013-12-23T07:28:29Z [Term] id: GO:0061582 name: intestinal epithelial cell migration namespace: biological_process def: "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." [GOC:dph] is_a: GO:0010631 ! epithelial cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0002563 ! intestinal epithelial cell relationship: results_in_movement_of CL:0002563 ! intestinal epithelial cell created_by: dph creation_date: 2013-12-23T07:30:55Z [Term] id: GO:0061626 name: pharyngeal arch artery morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." [GOC:BHF, GOC:dph, PMID:20122914] synonym: "aortic arch artery morphogenesis" BROAD [GOC:dph] is_a: GO:0048844 ! artery morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004363 ! pharyngeal arch artery relationship: part_of GO:0060037 ! pharyngeal system development relationship: results_in_morphogenesis_of UBERON:0004363 ! pharyngeal arch artery created_by: dph creation_date: 2014-05-09T15:34:06Z [Term] id: GO:0061682 name: seminal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a seminal vesicle are generated and organized." [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000998 ! seminal vesicle relationship: part_of GO:0061107 ! seminal vesicle development relationship: results_in_morphogenesis_of UBERON:0000998 ! seminal vesicle created_by: dph creation_date: 2015-03-04T13:33:49Z [Term] id: GO:0061683 name: branching involved in seminal vesicle morphogenesis namespace: biological_process def: "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." [GOC:dph, PMID:16916376] synonym: "gonecyst branching morphogenesis" EXACT [GOC:dph] synonym: "seminal gland branching morphogenesis" EXACT [GOC:dph] synonym: "seminal vesicle branching" EXACT [GOC:dph] synonym: "seminal vesicle branching morphogenesis" EXACT [GOC:dph] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: GO:0061138 ! morphogenesis of a branching epithelium intersection_of: part_of GO:0061682 ! seminal vesicle morphogenesis relationship: part_of GO:0061108 ! seminal vesicle epithelium development relationship: part_of GO:0061682 ! seminal vesicle morphogenesis created_by: dph creation_date: 2015-03-04T13:39:47Z [Term] id: GO:0061687 name: detoxification of inorganic compound namespace: biological_process def: "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." [GOC:vw] is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: has_input CHEBI:24835 ! inorganic molecular entity relationship: has_input CHEBI:24835 ! inorganic molecular entity created_by: dph creation_date: 2015-03-09T09:16:23Z [Term] id: GO:0061695 name: transferase complex, transferring phosphorus-containing groups namespace: cellular_component def: "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." [GOC:bhm, GOC:dph] is_a: GO:1990234 ! transferase complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0016772 ! transferase activity, transferring phosphorus-containing groups relationship: capable_of GO:0016772 ! transferase activity, transferring phosphorus-containing groups created_by: dph creation_date: 2015-05-06T11:22:38Z [Term] id: GO:0061792 name: secretory granule maturation namespace: biological_process def: "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling." [GOC:bf, GOC:dph, GOC:PARL, PMID:16618809] is_a: GO:0021700 ! developmental maturation is_a: GO:0033363 ! secretory granule organization intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of GO:0030141 ! secretory granule relationship: results_in_maturation_of GO:0030141 ! secretory granule created_by: dph creation_date: 2016-09-09T13:24:34Z [Term] id: GO:0061853 name: regulation of neuroblast migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097402 ! neuroblast migration relationship: regulates GO:0097402 ! neuroblast migration created_by: dph creation_date: 2017-03-08T18:17:07Z [Term] id: GO:0061854 name: positive regulation of neuroblast migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097402 ! neuroblast migration relationship: positively_regulates GO:0097402 ! neuroblast migration created_by: dph creation_date: 2017-03-08T18:22:30Z [Term] id: GO:0061855 name: negative regulation of neuroblast migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." [PMID:23149556] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0061853 ! regulation of neuroblast migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097402 ! neuroblast migration relationship: negatively_regulates GO:0097402 ! neuroblast migration created_by: dph creation_date: 2017-03-08T18:26:21Z [Term] id: GO:0061900 name: glial cell activation namespace: biological_process def: "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." [GOC:aruk, GOC:bc, PMID:18723082] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000125 ! glial cell relationship: has_input CL:0000125 ! glial cell relationship: part_of GO:0150076 ! neuroinflammatory response created_by: dph creation_date: 2017-06-13T13:06:23Z [Term] id: GO:0061938 name: protein localization to somatodendritic compartment namespace: biological_process def: "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." [PMID:18341993] synonym: "somatodendritic protein localization" EXACT [] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0036477 ! somatodendritic compartment relationship: has_target_end_location GO:0036477 ! somatodendritic compartment created_by: dph creation_date: 2017-09-08T13:22:26Z [Term] id: GO:0061951 name: establishment of protein localization to plasma membrane namespace: biological_process def: "The directed movement of a protein to a specific location in a plasma membrane." [GOC:dph, GOC:vw] is_a: GO:0072659 ! protein localization to plasma membrane is_a: GO:0090150 ! establishment of protein localization to membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: dph creation_date: 2017-10-26T12:55:15Z [Term] id: GO:0061971 name: replacement bone morphogenesis namespace: biological_process def: "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." [PMID:29852585] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0012075 ! replacement bone relationship: results_in_morphogenesis_of UBERON:0012075 ! replacement bone created_by: dph creation_date: 2018-02-12T18:10:59Z [Term] id: GO:0061972 name: dermal bone morphogenesis namespace: biological_process def: "The process in which bone which forms superficially in the organism are generated and organized." [PMID:12588850, PMID:15003632] is_a: GO:0061973 ! membrane bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0008907 ! dermal bone relationship: results_in_morphogenesis_of UBERON:0008907 ! dermal bone created_by: dph creation_date: 2018-02-12T18:16:21Z [Term] id: GO:0061973 name: membrane bone morphogenesis namespace: biological_process def: "The process in which bone which forms deep in the organism are generated and organized." [PMID:14579374] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0007842 ! membrane bone relationship: results_in_morphogenesis_of UBERON:0007842 ! membrane bone created_by: dph creation_date: 2018-02-12T18:21:09Z [Term] id: GO:0061983 name: meiosis II cell cycle process namespace: biological_process def: "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." [PMID:29385397] synonym: "second meiotic division" EXACT [PMID:29385397] is_a: GO:1903046 ! meiotic cell cycle process created_by: dph creation_date: 2018-02-14T22:37:44Z [Term] id: GO:0062009 name: secondary palate development namespace: biological_process def: "The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences." [PMID:28784960] is_a: GO:0060021 ! roof of mouth development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001716 ! secondary palate relationship: results_in_development_of UBERON:0001716 ! secondary palate created_by: dph creation_date: 2018-02-26T22:55:20Z [Term] id: GO:0062012 name: regulation of small molecule metabolic process namespace: biological_process def: "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." [GOC:vw] synonym: "regulation of small molecule metabolism" EXACT [] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044281 ! small molecule metabolic process relationship: regulates GO:0044281 ! small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:11:54Z [Term] id: GO:0062013 name: positive regulation of small molecule metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "positive regulation of small molecule metabolism" EXACT [] is_a: GO:0009893 ! positive regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044281 ! small molecule metabolic process relationship: positively_regulates GO:0044281 ! small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:25:10Z [Term] id: GO:0062014 name: negative regulation of small molecule metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." [GOC:vw] synonym: "negative regulation of small molecule metabolism" EXACT [] is_a: GO:0009892 ! negative regulation of metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044281 ! small molecule metabolic process relationship: negatively_regulates GO:0044281 ! small molecule metabolic process created_by: dph creation_date: 2018-03-19T14:27:23Z [Term] id: GO:0062023 name: collagen-containing extracellular matrix namespace: cellular_component def: "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells." [GOC:BHF, GOC:rph, PMID:21123617] is_a: GO:0031012 ! extracellular matrix relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa created_by: dph creation_date: 2018-04-13T12:47:21Z [Term] id: GO:0062033 name: positive regulation of mitotic sister chromatid segregation namespace: biological_process def: "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." [PMID:12773390] is_a: GO:0033047 ! regulation of mitotic sister chromatid segregation is_a: GO:0051984 ! positive regulation of chromosome segregation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0000070 ! mitotic sister chromatid segregation relationship: positively_regulates GO:0000070 ! mitotic sister chromatid segregation created_by: dph creation_date: 2018-04-23T14:32:23Z [Term] id: GO:0062094 name: stomach development namespace: biological_process def: "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ." [PMID:11967278] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000945 ! stomach relationship: part_of GO:0048565 ! digestive tract development relationship: results_in_development_of UBERON:0000945 ! stomach created_by: dph creation_date: 2018-11-20T18:15:45Z [Term] id: GO:0062149 name: detection of stimulus involved in sensory perception of pain namespace: biological_process def: "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal." [PMID:19837031] is_a: GO:0050906 ! detection of stimulus involved in sensory perception intersection_of: GO:0051606 ! detection of stimulus intersection_of: part_of GO:0019233 ! sensory perception of pain relationship: part_of GO:0019233 ! sensory perception of pain created_by: dph creation_date: 2019-09-13T13:48:47Z [Term] id: GO:0062237 name: protein localization to postsynapse namespace: biological_process def: "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." [PMID:31189538] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0098794 ! postsynapse relationship: has_target_end_location GO:0098794 ! postsynapse created_by: dph creation_date: 2020-04-20T13:58:43Z [Term] id: GO:0065002 name: intracellular protein transmembrane transport namespace: biological_process def: "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." [GOC:isa_complete] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "intracellular membrane translocation of a protein" EXACT [] synonym: "intracellular protein membrane transport" EXACT [] synonym: "intracellular protein transport across a membrane" EXACT [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0071806 ! protein transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0005622 ! intracellular anatomical structure intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0065003 name: protein-containing complex assembly namespace: biological_process alt_id: GO:0006461 alt_id: GO:0034622 alt_id: GO:0043623 def: "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." [GOC:jl] subset: goslim_chembl subset: goslim_drosophila subset: goslim_generic subset: goslim_metagenomics subset: goslim_pir subset: goslim_pombe subset: prokaryote_subset synonym: "cellular macromolecule complex assembly" RELATED [] synonym: "cellular protein complex assembly" EXACT [] synonym: "cellular protein-containing complex assembly" RELATED [] synonym: "chaperone activity" RELATED [] synonym: "macromolecular complex assembly" RELATED [] synonym: "macromolecule complex assembly" RELATED [] synonym: "protein complex assembly" RELATED [] synonym: "protein complex formation" RELATED [] is_a: GO:0022607 ! cellular component assembly is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032991 ! protein-containing complex relationship: results_in_assembly_of GO:0032991 ! protein-containing complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22580" xsd:anyURI [Term] id: GO:0065004 name: protein-DNA complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." [GOC:jl] synonym: "DNA-protein complex assembly" EXACT [GOC:mah] is_a: GO:0065003 ! protein-containing complex assembly is_a: GO:0071824 ! protein-DNA complex organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0032993 ! protein-DNA complex relationship: results_in_assembly_of GO:0032993 ! protein-DNA complex [Term] id: GO:0065007 name: biological regulation namespace: biological_process def: "Any process that modulates a measurable attribute of any biological process, quality or function." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] subset: gocheck_do_not_annotate subset: goslim_pir synonym: "regulation" BROAD [] is_a: GO:0008150 ! biological_process [Term] id: GO:0065008 name: regulation of biological quality namespace: biological_process def: "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw] subset: goslim_pir synonym: "regulation of biological attribute" EXACT [] synonym: "regulation of biological characteristic" EXACT [] is_a: GO:0065007 ! biological regulation [Term] id: GO:0065009 name: regulation of molecular function namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." [GOC:isa_complete] subset: gocheck_do_not_annotate subset: goslim_pir subset: goslim_plant subset: term_scheduled_for_obsoletion synonym: "regulation of a molecular function" EXACT [] is_a: GO:0065007 ! biological regulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003674 ! molecular_function relationship: regulates GO:0003674 ! molecular_function [Term] id: GO:0065010 name: extracellular membrane-bounded organelle namespace: cellular_component def: "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." [GOC:isa_complete] synonym: "extracellular membrane-enclosed organelle" EXACT [] is_a: GO:0043227 ! membrane-bounded organelle is_a: GO:0043230 ! extracellular organelle intersection_of: GO:0043227 ! membrane-bounded organelle intersection_of: part_of GO:0005576 ! extracellular region [Term] id: GO:0070013 name: intracellular organelle lumen namespace: cellular_component def: "An organelle lumen that is part of an intracellular organelle." [GOC:mah] is_a: GO:0043233 ! organelle lumen intersection_of: GO:0031974 ! membrane-enclosed lumen intersection_of: part_of GO:0043229 ! intracellular organelle relationship: part_of GO:0043229 ! intracellular organelle [Term] id: GO:0070050 name: neuron cellular homeostasis namespace: biological_process def: "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." [GOC:BHF, GOC:mah] synonym: "neuron maintenance" EXACT [] is_a: GO:0019725 ! cellular homeostasis intersection_of: GO:0019725 ! cellular homeostasis intersection_of: occurs_in CL:0000540 ! neuron relationship: occurs_in CL:0000540 ! neuron property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/24218" xsd:anyURI [Term] id: GO:0070062 name: extracellular exosome namespace: cellular_component def: "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894] synonym: "exosome" EXACT [GOC:pr] synonym: "extracellular vesicular exosome" EXACT [GOC:vesicles] is_a: GO:1903561 ! extracellular vesicle relationship: part_of GO:0005615 ! extracellular space [Term] id: GO:0070091 name: glucagon secretion namespace: biological_process def: "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." [GOC:BHF, GOC:rl] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:5391 ! glucagon relationship: has_primary_input CHEBI:5391 ! glucagon [Term] id: GO:0070092 name: regulation of glucagon secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070091 ! glucagon secretion relationship: regulates GO:0070091 ! glucagon secretion [Term] id: GO:0070093 name: negative regulation of glucagon secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "down regulation of glucagon secretion" EXACT [] synonym: "down-regulation of glucagon secretion" EXACT [] synonym: "downregulation of glucagon secretion" EXACT [] synonym: "inhibition of glucagon secretion" NARROW [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070091 ! glucagon secretion relationship: negatively_regulates GO:0070091 ! glucagon secretion [Term] id: GO:0070094 name: positive regulation of glucagon secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." [GOC:BHF, GOC:mah] synonym: "activation of glucagon secretion" NARROW [] synonym: "stimulation of glucagon secretion" NARROW [] synonym: "up regulation of glucagon secretion" EXACT [] synonym: "up-regulation of glucagon secretion" EXACT [] synonym: "upregulation of glucagon secretion" EXACT [] is_a: GO:0070092 ! regulation of glucagon secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070091 ! glucagon secretion relationship: positively_regulates GO:0070091 ! glucagon secretion [Term] id: GO:0070161 name: anchoring junction namespace: cellular_component def: "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." [ISBN:0815332181] synonym: "anchoring cell junction" EXACT [GOC:mah] is_a: GO:0030054 ! cell junction [Term] id: GO:0070192 name: chromosome organization involved in meiotic cell cycle namespace: biological_process def: "A process of chromosome organization that is involved in a meiotic cell cycle." [GOC:mah] synonym: "chromosome organisation involved in meiosis" EXACT [GOC:mah] synonym: "meiotic chromosome organization" EXACT [GOC:mah] is_a: GO:0051276 ! chromosome organization is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0051276 ! chromosome organization intersection_of: part_of GO:0051321 ! meiotic cell cycle [Term] id: GO:0070199 name: establishment of protein localization to chromosome namespace: biological_process def: "The directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0034502 ! protein localization to chromosome is_a: GO:0072594 ! establishment of protein localization to organelle intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005694 ! chromosome [Term] id: GO:0070201 name: regulation of establishment of protein localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation" EXACT [GOC:mah] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0045184 ! establishment of protein localization relationship: regulates GO:0045184 ! establishment of protein localization [Term] id: GO:0070202 name: regulation of establishment of protein localization to chromosome namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." [GOC:BHF, GOC:mah] synonym: "regulation of establishment of protein localisation to chromosome" EXACT [GOC:mah] is_a: GO:0070201 ! regulation of establishment of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070199 ! establishment of protein localization to chromosome relationship: regulates GO:0070199 ! establishment of protein localization to chromosome [Term] id: GO:0070227 name: lymphocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." [CL:0000542, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "lymphocyte apoptosis" NARROW [] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000542 ! lymphocyte relationship: occurs_in CL:0000542 ! lymphocyte [Term] id: GO:0070228 name: regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "regulation of lymphocyte apoptosis" NARROW [] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070227 ! lymphocyte apoptotic process relationship: regulates GO:0070227 ! lymphocyte apoptotic process [Term] id: GO:0070229 name: negative regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "down regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "down-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "downregulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "inhibition of lymphocyte apoptosis" NARROW [GOC:add] synonym: "negative regulation of lymphocyte apoptosis" NARROW [] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070227 ! lymphocyte apoptotic process relationship: negatively_regulates GO:0070227 ! lymphocyte apoptotic process [Term] id: GO:0070230 name: positive regulation of lymphocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "activation of lymphocyte apoptosis" NARROW [GOC:add] synonym: "positive regulation of lymphocyte apoptosis" NARROW [] synonym: "stimulation of lymphocyte apoptosis" NARROW [GOC:add] synonym: "up regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "up-regulation of lymphocyte apoptosis" EXACT [GOC:add] synonym: "upregulation of lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070227 ! lymphocyte apoptotic process relationship: positively_regulates GO:0070227 ! lymphocyte apoptotic process [Term] id: GO:0070231 name: T cell apoptotic process namespace: biological_process def: "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." [CL:0000084, GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "T cell apoptosis" NARROW [] synonym: "T lymphocyte apoptosis" EXACT [GOC:add] synonym: "T-cell apoptosis" EXACT [GOC:add] synonym: "T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070227 ! lymphocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000084 ! T cell relationship: occurs_in CL:0000084 ! T cell [Term] id: GO:0070232 name: regulation of T cell apoptotic process namespace: biological_process def: "Any process that modulates the occurrence or rate of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "regulation of T cell apoptosis" NARROW [] synonym: "regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070228 ! regulation of lymphocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070231 ! T cell apoptotic process relationship: regulates GO:0070231 ! T cell apoptotic process [Term] id: GO:0070233 name: negative regulation of T cell apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "down regulation of T cell apoptosis" EXACT [GOC:add] synonym: "down-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "downregulation of T cell apoptosis" EXACT [GOC:add] synonym: "inhibition of T cell apoptosis" NARROW [GOC:add] synonym: "negative regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "negative regulation of T cell apoptosis" NARROW [] synonym: "negative regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "negative regulation of T-lymphocyte apoptosis" EXACT [GOC:add] is_a: GO:0070229 ! negative regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070231 ! T cell apoptotic process relationship: negatively_regulates GO:0070231 ! T cell apoptotic process [Term] id: GO:0070234 name: positive regulation of T cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." [GOC:add, GOC:mtg_apoptosis, ISBN:0781765196] synonym: "activation of T cell apoptosis" NARROW [GOC:add] synonym: "positive regulation of programmed cell death of T cells by apoptosis" EXACT [GOC:add] synonym: "positive regulation of T cell apoptosis" NARROW [] synonym: "positive regulation of T lymphocyte apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-cell apoptosis" EXACT [GOC:add] synonym: "positive regulation of T-lymphocyte apoptosis" EXACT [GOC:add] synonym: "stimulation of T cell apoptosis" NARROW [GOC:add] synonym: "up regulation of T cell apoptosis" EXACT [GOC:add] synonym: "up-regulation of T cell apoptosis" EXACT [GOC:add] synonym: "upregulation of T cell apoptosis" EXACT [GOC:add] is_a: GO:0070230 ! positive regulation of lymphocyte apoptotic process is_a: GO:0070232 ! regulation of T cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070231 ! T cell apoptotic process relationship: positively_regulates GO:0070231 ! T cell apoptotic process [Term] id: GO:0070253 name: somatostatin secretion namespace: biological_process def: "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:mah] is_a: GO:0030072 ! peptide hormone secretion intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input CHEBI:64628 ! somatostatin relationship: has_primary_input CHEBI:64628 ! somatostatin [Term] id: GO:0070254 name: mucus secretion namespace: biological_process def: "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." [GOC:add, ISBN:068340007X, ISBN:0721662544] synonym: "mucus production" EXACT [GOC:add] is_a: GO:0007589 ! body fluid secretion is_a: GO:0032941 ! secretion by tissue intersection_of: GO:0046903 ! secretion intersection_of: has_primary_input UBERON:0000912 ! mucus relationship: has_primary_input UBERON:0000912 ! mucus [Term] id: GO:0070255 name: regulation of mucus secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "regulation of mucus production" EXACT [GOC:add] is_a: GO:0050878 ! regulation of body fluid levels is_a: GO:0051046 ! regulation of secretion is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070254 ! mucus secretion relationship: regulates GO:0070254 ! mucus secretion [Term] id: GO:0070256 name: negative regulation of mucus secretion namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "negative regulation of mucus production" EXACT [GOC:add] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070254 ! mucus secretion relationship: negatively_regulates GO:0070254 ! mucus secretion [Term] id: GO:0070257 name: positive regulation of mucus secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." [GOC:add] synonym: "positive regulation of mucus production" EXACT [GOC:add] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070255 ! regulation of mucus secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070254 ! mucus secretion relationship: positively_regulates GO:0070254 ! mucus secretion [Term] id: GO:0070285 name: pigment cell development namespace: biological_process def: "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." [GOC:cvs] is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0000147 ! pigment cell relationship: part_of GO:0050931 ! pigment cell differentiation relationship: results_in_development_of CL:0000147 ! pigment cell [Term] id: GO:0070341 name: fat cell proliferation namespace: biological_process def: "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." [GOC:mah, GOC:sl] synonym: "adipocyte proliferation" EXACT [GOC:sl] synonym: "adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000136 ! fat cell relationship: acts_on_population_of CL:0000136 ! fat cell [Term] id: GO:0070344 name: regulation of fat cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070341 ! fat cell proliferation relationship: regulates GO:0070341 ! fat cell proliferation [Term] id: GO:0070345 name: negative regulation of fat cell proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "down regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "down-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "downregulation of fat cell proliferation" EXACT [GOC:mah] synonym: "inhibition of fat cell proliferation" NARROW [GOC:mah] synonym: "negative regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "negative regulation of adipose cell proliferation" EXACT [GOC:sl] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070341 ! fat cell proliferation relationship: negatively_regulates GO:0070341 ! fat cell proliferation [Term] id: GO:0070346 name: positive regulation of fat cell proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of fat cell proliferation." [GOC:mah, GOC:sl] synonym: "activation of fat cell proliferation" NARROW [GOC:mah] synonym: "positive regulation of adipocyte proliferation" EXACT [GOC:sl] synonym: "positive regulation of adipose cell proliferation" EXACT [GOC:sl] synonym: "stimulation of fat cell proliferation" NARROW [GOC:mah] synonym: "up regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "up-regulation of fat cell proliferation" EXACT [GOC:mah] synonym: "upregulation of fat cell proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070344 ! regulation of fat cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070341 ! fat cell proliferation relationship: positively_regulates GO:0070341 ! fat cell proliferation [Term] id: GO:0070365 name: hepatocyte differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." [CL:0000182, PMID:7588884] synonym: "liver cell differentiation" EXACT [GOC:mah] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000182 ! hepatocyte relationship: part_of GO:0001889 ! liver development relationship: results_in_acquisition_of_features_of CL:0000182 ! hepatocyte [Term] id: GO:0070366 name: regulation of hepatocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070365 ! hepatocyte differentiation relationship: regulates GO:0070365 ! hepatocyte differentiation [Term] id: GO:0070367 name: negative regulation of hepatocyte differentiation namespace: biological_process def: "Any process that stops or decreases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "down regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "down-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "downregulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "inhibition of hepatocyte differentiation" NARROW [GOC:mah] synonym: "negative regulation of liver cell differentiation" EXACT [GOC:sl] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070365 ! hepatocyte differentiation relationship: negatively_regulates GO:0070365 ! hepatocyte differentiation [Term] id: GO:0070368 name: positive regulation of hepatocyte differentiation namespace: biological_process def: "Any process that activates or increases the rate or extent of hepatocyte differentiation." [GOC:mah, GOC:sl] synonym: "activation of hepatocyte differentiation" NARROW [GOC:mah] synonym: "positive regulation of liver cell differentiation" EXACT [GOC:sl] synonym: "stimulation of hepatocyte differentiation" NARROW [GOC:mah] synonym: "up regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "up-regulation of hepatocyte differentiation" EXACT [GOC:mah] synonym: "upregulation of hepatocyte differentiation" EXACT [GOC:mah] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0070366 ! regulation of hepatocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070365 ! hepatocyte differentiation relationship: positively_regulates GO:0070365 ! hepatocyte differentiation [Term] id: GO:0070382 name: exocytic vesicle namespace: cellular_component def: "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." [GOC:kad, GOC:mah] synonym: "exocytic constitutive secretory pathway transport vesicle" EXACT [] synonym: "exocytotic vesicle" EXACT [GOC:kad] is_a: GO:0030133 ! transport vesicle is_a: GO:0099503 ! secretory vesicle intersection_of: GO:0030133 ! transport vesicle intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane [Term] id: GO:0070444 name: oligodendrocyte progenitor proliferation namespace: biological_process def: "The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system." [GOC:mah, GOC:sl, PMID:15504915] synonym: "oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:0061351 ! neural precursor cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0002453 ! oligodendrocyte precursor cell relationship: acts_on_population_of CL:0002453 ! oligodendrocyte precursor cell relationship: part_of GO:0042063 ! gliogenesis [Term] id: GO:0070445 name: regulation of oligodendrocyte progenitor proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] synonym: "regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070444 ! oligodendrocyte progenitor proliferation relationship: regulates GO:0070444 ! oligodendrocyte progenitor proliferation [Term] id: GO:0070446 name: negative regulation of oligodendrocyte progenitor proliferation namespace: biological_process def: "Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] synonym: "negative regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:0014014 ! negative regulation of gliogenesis is_a: GO:0070445 ! regulation of oligodendrocyte progenitor proliferation is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation relationship: negatively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation [Term] id: GO:0070447 name: positive regulation of oligodendrocyte progenitor proliferation namespace: biological_process def: "Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation." [GOC:mah, GOC:sl] synonym: "positive regulation of oligodendrocyte precursor proliferation" EXACT [GOC:mah] is_a: GO:0014015 ! positive regulation of gliogenesis is_a: GO:0070445 ! regulation of oligodendrocyte progenitor proliferation is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation relationship: positively_regulates GO:0070444 ! oligodendrocyte progenitor proliferation [Term] id: GO:0070507 name: regulation of microtubule cytoskeleton organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." [GOC:mah] synonym: "regulation of microtubule cytoskeleton organisation" EXACT [GOC:mah] synonym: "regulation of microtubule dynamics" EXACT [GOC:dph, GOC:tb] is_a: GO:0032886 ! regulation of microtubule-based process is_a: GO:0051493 ! regulation of cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0000226 ! microtubule cytoskeleton organization relationship: regulates GO:0000226 ! microtubule cytoskeleton organization [Term] id: GO:0070633 name: transepithelial transport namespace: biological_process def: "The directed movement of a substance from one side of an epithelium to the other." [GOC:mah, GOC:yaf, ISBN:0716731363] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: results_in_transport_across UBERON:0000483 ! epithelium relationship: results_in_transport_across UBERON:0000483 ! epithelium created_by: mah creation_date: 2009-05-06T03:31:02Z [Term] id: GO:0070634 name: transepithelial ammonium transport namespace: biological_process def: "The directed movement of ammonium ions from one side of an epithelium to the other." [GOC:mah, GOC:yaf] is_a: GO:0070633 ! transepithelial transport is_a: GO:0071705 ! nitrogen compound transport intersection_of: GO:0070633 ! transepithelial transport intersection_of: has_primary_input CHEBI:28938 ! ammonium relationship: has_primary_input CHEBI:28938 ! ammonium created_by: mah creation_date: 2009-05-06T03:34:43Z [Term] id: GO:0070661 name: leukocyte proliferation namespace: biological_process def: "The expansion of a leukocyte population by cell division." [GOC:add] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000738 ! leukocyte relationship: acts_on_population_of CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata created_by: mah creation_date: 2009-05-28T05:25:28Z [Term] id: GO:0070663 name: regulation of leukocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070661 ! leukocyte proliferation relationship: regulates GO:0070661 ! leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:30:39Z [Term] id: GO:0070664 name: negative regulation of leukocyte proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "down regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "down-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "downregulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "inhibition of leukocyte proliferation" NARROW [GOC:mah] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070661 ! leukocyte proliferation relationship: negatively_regulates GO:0070661 ! leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:34:50Z [Term] id: GO:0070665 name: positive regulation of leukocyte proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." [GOC:add, GOC:mah] synonym: "activation of leukocyte proliferation" NARROW [GOC:mah] synonym: "stimulation of leukocyte proliferation" NARROW [GOC:mah] synonym: "up regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "up-regulation of leukocyte proliferation" EXACT [GOC:mah] synonym: "upregulation of leukocyte proliferation" EXACT [GOC:mah] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0070663 ! regulation of leukocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070661 ! leukocyte proliferation relationship: positively_regulates GO:0070661 ! leukocyte proliferation created_by: mah creation_date: 2009-05-28T05:36:46Z [Term] id: GO:0070727 name: cellular macromolecule localization namespace: biological_process def: "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." [GOC:mah] synonym: "cellular macromolecule localisation" EXACT [GOC:mah] is_a: GO:0033036 ! macromolecule localization is_a: GO:0051641 ! cellular localization created_by: mah creation_date: 2009-06-16T04:08:29Z [Term] id: GO:0070831 name: basement membrane assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." [GOC:mah] comment: Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer. is_a: GO:0071711 ! basement membrane organization is_a: GO:0085029 ! extracellular matrix assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0005604 ! basement membrane relationship: results_in_assembly_of GO:0005604 ! basement membrane created_by: mah creation_date: 2009-07-23T05:01:51Z [Term] id: GO:0070857 name: regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "regulation of bile acid formation" EXACT [GOC:mah] synonym: "regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010565 ! regulation of cellular ketone metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0050810 ! regulation of steroid biosynthetic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006699 ! bile acid biosynthetic process relationship: regulates GO:0006699 ! bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:09:02Z [Term] id: GO:0070858 name: negative regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "down regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "down-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "downregulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "inhibition of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "negative regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "negative regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "negative regulation of bile acid formation" EXACT [GOC:mah] synonym: "negative regulation of bile acid synthesis" EXACT [GOC:mah] is_a: GO:0010894 ! negative regulation of steroid biosynthetic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process is_a: GO:1904252 ! negative regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006699 ! bile acid biosynthetic process relationship: negatively_regulates GO:0006699 ! bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:16:40Z [Term] id: GO:0070859 name: positive regulation of bile acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." [GOC:BHF, GOC:mah] synonym: "activation of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "positive regulation of bile acid anabolism" EXACT [GOC:mah] synonym: "positive regulation of bile acid biosynthesis" EXACT [GOC:mah] synonym: "positive regulation of bile acid formation" EXACT [GOC:mah] synonym: "positive regulation of bile acid synthesis" EXACT [GOC:mah] synonym: "stimulation of bile acid biosynthetic process" NARROW [GOC:mah] synonym: "up regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "up-regulation of bile acid biosynthetic process" EXACT [GOC:mah] synonym: "upregulation of bile acid biosynthetic process" EXACT [GOC:mah] is_a: GO:0010893 ! positive regulation of steroid biosynthetic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0070857 ! regulation of bile acid biosynthetic process is_a: GO:1904253 ! positive regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006699 ! bile acid biosynthetic process relationship: positively_regulates GO:0006699 ! bile acid biosynthetic process created_by: mah creation_date: 2009-08-14T03:22:58Z [Term] id: GO:0070873 name: regulation of glycogen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0032881 ! regulation of polysaccharide metabolic process is_a: GO:0043467 ! regulation of generation of precursor metabolites and energy intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005977 ! glycogen metabolic process relationship: regulates GO:0005977 ! glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:44:53Z [Term] id: GO:0070874 name: negative regulation of glycogen metabolic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "negative regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010605 ! negative regulation of macromolecule metabolic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005977 ! glycogen metabolic process relationship: negatively_regulates GO:0005977 ! glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:50:41Z [Term] id: GO:0070875 name: positive regulation of glycogen metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen." [GOC:mah] synonym: "positive regulation of glycogen metabolism" EXACT [GOC:mah] is_a: GO:0010604 ! positive regulation of macromolecule metabolic process is_a: GO:0010907 ! positive regulation of glucose metabolic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0070873 ! regulation of glycogen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005977 ! glycogen metabolic process relationship: positively_regulates GO:0005977 ! glycogen metabolic process created_by: mah creation_date: 2009-08-20T02:53:55Z [Term] id: GO:0070925 name: organelle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." [GOC:mah] subset: goslim_yeast is_a: GO:0006996 ! organelle organization is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0043226 ! organelle relationship: results_in_assembly_of GO:0043226 ! organelle created_by: mah creation_date: 2009-09-15T03:00:51Z [Term] id: GO:0070977 name: bone maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." [GOC:dph, GOC:mah] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0001474 ! bone element relationship: part_of GO:0060348 ! bone development relationship: results_in_maturation_of UBERON:0001474 ! bone element created_by: mah creation_date: 2009-10-05T04:35:31Z [Term] id: GO:0070997 name: neuron death namespace: biological_process def: "The process of cell death in a neuron." [GOC:BHF, GOC:mah] comment: This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate. synonym: "neuron cell death" EXACT [GOC:mah, GOC:rl] synonym: "neuronal cell death" EXACT [GOC:mah] is_a: GO:0008219 ! cell death intersection_of: GO:0008219 ! cell death intersection_of: occurs_in CL:0000540 ! neuron relationship: occurs_in CL:0000540 ! neuron created_by: mah creation_date: 2009-11-03T02:37:17Z [Term] id: GO:0071168 name: protein localization to chromatin namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0034502 ! protein localization to chromosome intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0000785 ! chromatin relationship: has_target_end_location GO:0000785 ! chromatin created_by: mah creation_date: 2009-11-20T11:51:20Z [Term] id: GO:0071169 name: establishment of protein localization to chromatin namespace: biological_process def: "The directed movement of a protein to a part of a chromosome that is organized into chromatin." [GOC:mah] synonym: "establishment of protein localisation to chromatin" EXACT [GOC:mah] is_a: GO:0070199 ! establishment of protein localization to chromosome is_a: GO:0071168 ! protein localization to chromatin intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0000785 ! chromatin created_by: mah creation_date: 2009-11-20T11:52:43Z [Term] id: GO:0071425 name: hematopoietic stem cell proliferation namespace: biological_process def: "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." [CL:0000037, GOC:add, GOC:BHF, GOC:mah, GOC:rl] synonym: "hemopoietic stem cell proliferation" EXACT [] is_a: GO:0072089 ! stem cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000037 ! hematopoietic stem cell relationship: acts_on_population_of CL:0000037 ! hematopoietic stem cell relationship: part_of GO:0030097 ! hemopoiesis created_by: mah creation_date: 2009-12-16T10:22:52Z [Term] id: GO:0071599 name: otic vesicle development namespace: biological_process def: "The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:mah] is_a: GO:0007423 ! sensory organ development is_a: GO:0035295 ! tube development is_a: GO:0048839 ! inner ear development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003051 ! ear vesicle relationship: results_in_development_of UBERON:0003051 ! ear vesicle created_by: mah creation_date: 2010-02-04T04:07:17Z [Term] id: GO:0071600 name: otic vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear." [GOC:mah] is_a: GO:0042472 ! inner ear morphogenesis is_a: GO:0048562 ! embryonic organ morphogenesis is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003051 ! ear vesicle relationship: part_of GO:0071599 ! otic vesicle development relationship: results_in_morphogenesis_of UBERON:0003051 ! ear vesicle created_by: mah creation_date: 2010-02-04T04:07:27Z [Term] id: GO:0071626 name: mastication namespace: biological_process def: "The process of biting and mashing food with the teeth prior to swallowing." [GOC:gvg] synonym: "chewing" EXACT [GOC:mah] is_a: GO:0022600 ! digestive system process created_by: mah creation_date: 2010-02-10T11:19:48Z [Term] id: GO:0071674 name: mononuclear cell migration namespace: biological_process def: "The movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000842 ! mononuclear cell relationship: results_in_movement_of CL:0000842 ! mononuclear cell created_by: mah creation_date: 2010-02-16T02:11:00Z [Term] id: GO:0071675 name: regulation of mononuclear cell migration namespace: biological_process def: "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] is_a: GO:0002685 ! regulation of leukocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071674 ! mononuclear cell migration relationship: regulates GO:0071674 ! mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:11:53Z [Term] id: GO:0071676 name: negative regulation of mononuclear cell migration namespace: biological_process def: "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "down regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "down-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "downregulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "inhibition of mononuclear cell migration" NARROW [GOC:mah] is_a: GO:0002686 ! negative regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071674 ! mononuclear cell migration relationship: negatively_regulates GO:0071674 ! mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:13:55Z [Term] id: GO:0071677 name: positive regulation of mononuclear cell migration namespace: biological_process def: "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." [GOC:mah] synonym: "activation of mononuclear cell migration" NARROW [GOC:mah] synonym: "stimulation of mononuclear cell migration" NARROW [GOC:mah] synonym: "up regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "up-regulation of mononuclear cell migration" EXACT [GOC:mah] synonym: "upregulation of mononuclear cell migration" EXACT [GOC:mah] is_a: GO:0002687 ! positive regulation of leukocyte migration is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071674 ! mononuclear cell migration relationship: positively_regulates GO:0071674 ! mononuclear cell migration created_by: mah creation_date: 2010-02-16T02:15:29Z [Term] id: GO:0071692 name: protein localization to extracellular region namespace: biological_process def: "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." [GOC:mah] synonym: "protein localisation in extracellular region" EXACT [GOC:mah] synonym: "protein localization in extracellular region" EXACT [] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005576 ! extracellular region created_by: mah creation_date: 2010-02-25T04:00:13Z [Term] id: GO:0071695 name: anatomical structure maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." [GOC:mah] is_a: GO:0021700 ! developmental maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CARO:0000003 ! connected anatomical structure relationship: part_of GO:0048856 ! anatomical structure development relationship: results_in_maturation_of CARO:0000003 ! connected anatomical structure created_by: mah creation_date: 2010-03-02T11:43:38Z [Term] id: GO:0071696 name: ectodermal placode development namespace: biological_process def: "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005085 ! ectodermal placode relationship: results_in_development_of UBERON:0005085 ! ectodermal placode created_by: mah creation_date: 2010-03-02T11:48:01Z [Term] id: GO:0071697 name: ectodermal placode morphogenesis namespace: biological_process def: "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." [GOC:mah] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005085 ! ectodermal placode relationship: part_of GO:0071696 ! ectodermal placode development relationship: results_in_morphogenesis_of UBERON:0005085 ! ectodermal placode created_by: mah creation_date: 2010-03-02T11:49:51Z [Term] id: GO:0071698 name: olfactory placode development namespace: biological_process def: "The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] is_a: GO:0071696 ! ectodermal placode development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003050 ! olfactory placode relationship: results_in_development_of UBERON:0003050 ! olfactory placode created_by: mah creation_date: 2010-03-02T12:45:14Z [Term] id: GO:0071699 name: olfactory placode morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] is_a: GO:0048598 ! embryonic morphogenesis is_a: GO:0071697 ! ectodermal placode morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003050 ! olfactory placode relationship: part_of GO:0071698 ! olfactory placode development relationship: results_in_morphogenesis_of UBERON:0003050 ! olfactory placode created_by: mah creation_date: 2010-03-02T12:45:45Z [Term] id: GO:0071700 name: olfactory placode maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity." [GOC:mah] is_a: GO:0071695 ! anatomical structure maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0003050 ! olfactory placode relationship: part_of GO:0071698 ! olfactory placode development relationship: results_in_maturation_of UBERON:0003050 ! olfactory placode created_by: mah creation_date: 2010-03-02T01:10:54Z [Term] id: GO:0071702 name: organic substance transport namespace: biological_process def: "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity relationship: has_primary_input CHEBI:50860 ! organic molecular entity created_by: mah creation_date: 2010-03-08T02:15:14Z [Term] id: GO:0071704 name: organic substance metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." [GOC:mah] synonym: "organic molecular entity metabolic process" EXACT [] synonym: "organic molecular entity metabolism" EXACT [] synonym: "organic substance metabolism" EXACT [] is_a: GO:0008152 ! metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:50860 ! organic molecular entity relationship: has_primary_input_or_output CHEBI:50860 ! organic molecular entity created_by: mah creation_date: 2010-03-08T03:32:18Z [Term] id: GO:0071705 name: nitrogen compound transport namespace: biological_process def: "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:51143 ! nitrogen molecular entity relationship: has_primary_input CHEBI:51143 ! nitrogen molecular entity created_by: mah creation_date: 2010-03-08T03:56:28Z [Term] id: GO:0071709 name: membrane assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a membrane." [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0061024 ! membrane organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0016020 ! membrane relationship: part_of GO:0044091 ! membrane biogenesis relationship: results_in_assembly_of GO:0016020 ! membrane created_by: mah creation_date: 2010-03-10T11:19:17Z [Term] id: GO:0071711 name: basement membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." [GOC:mah] comment: Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer. synonym: "basement membrane organisation" EXACT [GOC:mah] is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005604 ! basement membrane relationship: results_in_organization_of GO:0005604 ! basement membrane created_by: mah creation_date: 2010-03-10T11:57:10Z [Term] id: GO:0071763 name: nuclear membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." [GOC:mah] synonym: "nuclear membrane organisation" EXACT [GOC:mah] synonym: "nuclear membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0061024 ! membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0031965 ! nuclear membrane relationship: part_of GO:0006998 ! nuclear envelope organization relationship: results_in_organization_of GO:0031965 ! nuclear membrane created_by: mah creation_date: 2010-03-29T03:59:35Z [Term] id: GO:0071764 name: nuclear outer membrane organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." [GOC:mah] synonym: "nuclear outer membrane organisation" EXACT [GOC:mah] synonym: "nuclear outer membrane organization and biogenesis" RELATED [GOC:mah] is_a: GO:0071763 ! nuclear membrane organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0005640 ! nuclear outer membrane relationship: results_in_organization_of GO:0005640 ! nuclear outer membrane created_by: mah creation_date: 2010-03-29T04:03:37Z [Term] id: GO:0071806 name: protein transmembrane transport namespace: biological_process def: "The process in which a protein is transported across a membrane." [GOC:mah, GOC:vw] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "protein membrane transport" EXACT [] is_a: GO:0015031 ! protein transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: mah creation_date: 2010-09-03T02:54:26Z [Term] id: GO:0071824 name: protein-DNA complex organization namespace: biological_process def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." [GOC:mah] synonym: "DNA-protein complex subunit organization" EXACT [GOC:mah] synonym: "protein-DNA complex subunit organisation" EXACT [GOC:mah] synonym: "protein-DNA complex subunit organization" EXACT [] is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0032993 ! protein-DNA complex relationship: results_in_organization_of GO:0032993 ! protein-DNA complex created_by: mah creation_date: 2010-09-08T10:03:26Z [Term] id: GO:0071826 name: protein-RNA complex organization namespace: biological_process def: "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." [GOC:mah] synonym: "protein-RNA complex subunit organization" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organisation" EXACT [GOC:mah] synonym: "ribonucleoprotein complex subunit organization" EXACT [] synonym: "RNA-protein complex subunit organization" EXACT [GOC:mah] is_a: GO:0043933 ! protein-containing complex organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:1990904 ! ribonucleoprotein complex relationship: results_in_organization_of GO:1990904 ! ribonucleoprotein complex property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/25143" xsd:anyURI created_by: mah creation_date: 2010-09-08T10:10:35Z [Term] id: GO:0071840 name: cellular component organization or biogenesis namespace: biological_process alt_id: GO:0071841 def: "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." [GOC:mah] subset: goslim_flybase_ribbon subset: goslim_metagenomics synonym: "cellular component organisation or biogenesis" EXACT [GOC:mah] synonym: "cellular component organisation or biogenesis at cellular level" EXACT [GOC:mah] synonym: "cellular component organization or biogenesis at cellular level" EXACT [] is_a: GO:0009987 ! cellular process created_by: mah creation_date: 2010-09-10T01:39:16Z [Term] id: GO:0071867 name: response to monoamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." [GOC:mah] synonym: "response to monoamine stimulus" EXACT [GOC:dos] is_a: GO:0010243 ! response to organonitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:63534 ! monoamine relationship: has_input CHEBI:63534 ! monoamine created_by: mah creation_date: 2010-09-13T02:36:37Z [Term] id: GO:0071869 name: response to catecholamine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." [GOC:BHF, GOC:mah] synonym: "response to catecholamine stimulus" EXACT [GOC:dos] is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0071867 ! response to monoamine is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:33567 ! catecholamine relationship: has_input CHEBI:33567 ! catecholamine created_by: mah creation_date: 2010-09-13T02:51:13Z [Term] id: GO:0071873 name: response to norepinephrine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." [GOC:BHF, GOC:mah] comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. synonym: "response to noradrenaline stimulus" EXACT [GOC:mah] synonym: "response to norepinephrine stimulus" EXACT [GOC:dos] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:72587 ! (R)-noradrenaline(1+) relationship: has_input CHEBI:72587 ! (R)-noradrenaline(1+) created_by: mah creation_date: 2010-09-13T03:31:53Z [Term] id: GO:0071887 name: leukocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." [CL:0000738, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542). synonym: "leukocyte apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000738 ! leukocyte relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in CL:0000738 ! leukocyte relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata created_by: mah creation_date: 2010-09-14T12:44:09Z [Term] id: GO:0071895 name: odontoblast differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin." [GOC:sl, PMID:20425127] is_a: GO:0060563 ! neuroepithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000060 ! odontoblast relationship: results_in_acquisition_of_features_of CL:0000060 ! odontoblast created_by: mah creation_date: 2010-09-14T04:00:40Z [Term] id: GO:0071897 name: DNA biosynthetic process namespace: biological_process def: "The biosynthetic process resulting in the formation of DNA." [GOC:mah] synonym: "DNA anabolism" EXACT [GOC:mah] synonym: "DNA biosynthesis" EXACT [GOC:mah] synonym: "DNA formation" EXACT [GOC:mah] synonym: "DNA synthesis" EXACT [GOC:mah] is_a: GO:0006259 ! DNA metabolic process is_a: GO:0009059 ! macromolecule biosynthetic process is_a: GO:0034654 ! nucleobase-containing compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:16991 ! deoxyribonucleic acid relationship: has_primary_output CHEBI:16991 ! deoxyribonucleic acid created_by: mah creation_date: 2010-09-15T02:14:33Z [Term] id: GO:0071944 name: cell periphery namespace: cellular_component def: "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." [GOC:pdt] subset: goslim_flybase_ribbon is_a: GO:0110165 ! cellular anatomical entity created_by: mah creation_date: 2010-10-04T01:51:47Z [Term] id: GO:0071953 name: elastic fiber namespace: cellular_component def: "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." [GOC:BHF, GOC:mah, PMID:20236620] synonym: "elastic fibre" EXACT [GOC:mah] synonym: "elastin fiber" EXACT [GOC:BHF] is_a: GO:0099512 ! supramolecular fiber relationship: part_of GO:0031012 ! extracellular matrix created_by: mah creation_date: 2010-10-11T11:44:57Z [Term] id: GO:0071971 name: extracellular exosome assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." [GOC:mah, GOC:tfm, PMID:19442504, PMID:27462458] synonym: "extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:0016050 ! vesicle organization is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0070062 ! extracellular exosome relationship: part_of GO:0097734 ! extracellular exosome biogenesis relationship: results_in_assembly_of GO:0070062 ! extracellular exosome created_by: mah creation_date: 2010-10-18T03:44:18Z [Term] id: GO:0072001 name: renal system development namespace: biological_process def: "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels." [GOC:mtg_kidney_jan10, GOC:yaf, http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System] subset: gocheck_do_not_annotate synonym: "urinary system development" BROAD [GOC:yaf] synonym: "urinary tract development" BROAD [GOC:yaf, PMID:17881463] is_a: GO:0048731 ! system development intersection_of: GO:0048731 ! system development intersection_of: results_in_development_of UBERON:0001008 ! renal system relationship: results_in_development_of UBERON:0001008 ! renal system created_by: mah creation_date: 2010-01-25T10:31:00Z [Term] id: GO:0072003 name: kidney rudiment formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] synonym: "kidney anlage formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005095 ! kidney rudiment relationship: part_of GO:0060993 ! kidney morphogenesis relationship: results_in_formation_of UBERON:0005095 ! kidney rudiment created_by: mah creation_date: 2010-01-25T11:18:58Z [Term] id: GO:0072006 name: nephron development namespace: biological_process def: "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] synonym: "nephrogenesis" RELATED [GOC:rph] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001285 ! nephron relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0001285 ! nephron created_by: mah creation_date: 2010-01-25T01:37:16Z [Term] id: GO:0072009 name: nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004211 ! nephron epithelium relationship: part_of GO:0072006 ! nephron development relationship: results_in_development_of UBERON:0004211 ! nephron epithelium created_by: mah creation_date: 2010-01-25T02:01:39Z [Term] id: GO:0072028 name: nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001285 ! nephron relationship: part_of GO:0060993 ! kidney morphogenesis relationship: part_of GO:0072006 ! nephron development relationship: results_in_morphogenesis_of UBERON:0001285 ! nephron created_by: mah creation_date: 2010-01-25T02:45:52Z [Term] id: GO:0072033 name: renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] synonym: "nephron epithelium formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0004209 ! renal vesicle relationship: part_of GO:0072077 ! renal vesicle morphogenesis relationship: results_in_formation_of UBERON:0004209 ! renal vesicle created_by: mah creation_date: 2010-01-25T02:57:03Z [Term] id: GO:0072036 name: mesenchymal to epithelial transition involved in renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development is_a: GO:0060231 ! mesenchymal to epithelial transition intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0072033 ! renal vesicle formation relationship: part_of GO:0072033 ! renal vesicle formation created_by: mah creation_date: 2010-01-25T03:04:24Z [Term] id: GO:0072038 name: mesenchymal stem cell maintenance involved in nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0035019 ! somatic stem cell population maintenance relationship: part_of GO:0072028 ! nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:08:05Z [Term] id: GO:0072039 name: regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904672 ! regulation of somatic stem cell population maintenance is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:08:34Z [Term] id: GO:0072040 name: negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis is_a: GO:1904673 ! negative regulation of somatic stem cell population maintenance is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: negatively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: negatively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:09:30Z [Term] id: GO:0072041 name: positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis is_a: GO:1904674 ! positive regulation of somatic stem cell population maintenance is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis relationship: positively_regulates GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: positively_regulates GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis created_by: mah creation_date: 2010-01-25T03:10:32Z [Term] id: GO:0072044 name: collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001232 ! collecting duct of renal tubule relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0001232 ! collecting duct of renal tubule created_by: mah creation_date: 2010-01-25T03:18:06Z [Term] id: GO:0072048 name: renal system pattern specification namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system." [GOC:mtg_kidney_jan10] subset: gocheck_do_not_annotate synonym: "renal system pattern formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0007389 ! pattern specification process relationship: part_of GO:0072001 ! renal system development created_by: mah creation_date: 2010-01-25T03:31:51Z [Term] id: GO:0072055 name: renal cortex development namespace: biological_process def: "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001225 ! cortex of kidney relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0001225 ! cortex of kidney created_by: mah creation_date: 2010-01-25T04:01:12Z [Term] id: GO:0072059 name: cortical collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004203 ! cortical collecting duct relationship: results_in_development_of UBERON:0004203 ! cortical collecting duct created_by: mah creation_date: 2010-01-25T04:07:07Z [Term] id: GO:0072071 name: kidney interstitial fibroblast differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell differentiation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000692 ! kidney interstitial fibroblast relationship: results_in_acquisition_of_features_of CL:1000692 ! kidney interstitial fibroblast created_by: mah creation_date: 2010-01-25T04:34:31Z [Term] id: GO:0072073 name: kidney epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004819 ! kidney epithelium relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0004819 ! kidney epithelium created_by: mah creation_date: 2010-01-25T04:37:42Z [Term] id: GO:0072074 name: kidney mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003918 ! kidney mesenchyme relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0003918 ! kidney mesenchyme created_by: mah creation_date: 2010-01-25T04:39:04Z [Term] id: GO:0072075 name: metanephric mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003220 ! metanephric mesenchyme relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0003220 ! metanephric mesenchyme created_by: mah creation_date: 2010-01-25T04:40:11Z [Term] id: GO:0072076 name: nephrogenic mesenchyme development namespace: biological_process def: "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072074 ! kidney mesenchyme development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004208 ! nephrogenic mesenchyme relationship: part_of GO:0072006 ! nephron development relationship: results_in_development_of UBERON:0004208 ! nephrogenic mesenchyme created_by: mah creation_date: 2010-01-25T04:40:44Z [Term] id: GO:0072077 name: renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004209 ! renal vesicle relationship: part_of GO:0072087 ! renal vesicle development relationship: part_of GO:0072088 ! nephron epithelium morphogenesis relationship: results_in_morphogenesis_of UBERON:0004209 ! renal vesicle created_by: mah creation_date: 2010-02-01T02:21:06Z [Term] id: GO:0072078 name: nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061333 ! renal tubule morphogenesis is_a: GO:0072088 ! nephron epithelium morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001231 ! nephron tubule relationship: part_of GO:0072080 ! nephron tubule development relationship: results_in_morphogenesis_of UBERON:0001231 ! nephron tubule created_by: mah creation_date: 2010-02-01T02:25:14Z [Term] id: GO:0072079 name: nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0001838 ! embryonic epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001231 ! nephron tubule relationship: part_of GO:0072078 ! nephron tubule morphogenesis relationship: results_in_formation_of UBERON:0001231 ! nephron tubule created_by: mah creation_date: 2010-02-01T02:29:26Z [Term] id: GO:0072080 name: nephron tubule development namespace: biological_process def: "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0061326 ! renal tubule development is_a: GO:0072009 ! nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001231 ! nephron tubule relationship: results_in_development_of UBERON:0001231 ! nephron tubule created_by: mah creation_date: 2010-02-01T02:32:12Z [Term] id: GO:0072087 name: renal vesicle development namespace: biological_process def: "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004209 ! renal vesicle relationship: part_of GO:0072009 ! nephron epithelium development relationship: results_in_development_of UBERON:0004209 ! renal vesicle created_by: mah creation_date: 2010-02-08T01:18:31Z [Term] id: GO:0072088 name: nephron epithelium morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron." [GOC:mtg_kidney_jan10] is_a: GO:0002009 ! morphogenesis of an epithelium intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004211 ! nephron epithelium relationship: part_of GO:0072009 ! nephron epithelium development relationship: part_of GO:0072028 ! nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0004211 ! nephron epithelium created_by: mah creation_date: 2010-02-08T01:19:06Z [Term] id: GO:0072089 name: stem cell proliferation namespace: biological_process def: "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000034 ! stem cell relationship: acts_on_population_of CL:0000034 ! stem cell relationship: has_part GO:0017145 ! stem cell division created_by: mah creation_date: 2010-02-08T02:03:36Z [Term] id: GO:0072091 name: regulation of stem cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." [GOC:mtg_kidney_jan10] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072089 ! stem cell proliferation relationship: regulates GO:0072089 ! stem cell proliferation created_by: mah creation_date: 2010-02-08T02:09:03Z [Term] id: GO:0072093 name: metanephric renal vesicle formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the metanephros." [GOC:mtg_kidney_jan10] synonym: "metanephros formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0072033 ! renal vesicle formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005147 ! metanephric renal vesicle relationship: part_of GO:0072283 ! metanephric renal vesicle morphogenesis relationship: results_in_formation_of UBERON:0005147 ! metanephric renal vesicle created_by: mah creation_date: 2010-02-10T01:17:11Z [Term] id: GO:0072098 name: anterior/posterior pattern specification involved in kidney development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "anterior/posterior pattern formation involved in kidney development" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "kidney anterior/posterior pattern specification" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0009952 ! anterior/posterior pattern specification is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-02-10T02:06:24Z [Term] id: GO:0072099 name: anterior/posterior pattern specification involved in ureteric bud development namespace: biological_process def: "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "ureteric bud anterior/posterior pattern formation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0061227 ! pattern specification involved in mesonephros development is_a: GO:0072098 ! anterior/posterior pattern specification involved in kidney development intersection_of: GO:0009952 ! anterior/posterior pattern specification intersection_of: part_of GO:0001657 ! ureteric bud development relationship: part_of GO:0001657 ! ureteric bud development created_by: mah creation_date: 2010-02-10T02:12:09Z [Term] id: GO:0072105 name: ureteric peristalsis namespace: biological_process def: "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0014849 ! ureter smooth muscle contraction is_a: GO:0030432 ! peristalsis intersection_of: GO:0030432 ! peristalsis intersection_of: occurs_in UBERON:0000056 ! ureter relationship: occurs_in UBERON:0000056 ! ureter created_by: mah creation_date: 2010-02-10T03:07:54Z [Term] id: GO:0072106 name: regulation of ureteric bud formation namespace: biological_process def: "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0061217 ! regulation of mesonephros development is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060676 ! ureteric bud formation relationship: regulates GO:0060676 ! ureteric bud formation created_by: mah creation_date: 2010-02-12T02:34:40Z [Term] id: GO:0072107 name: positive regulation of ureteric bud formation namespace: biological_process def: "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." [GOC:mtg_kidney_jan10] is_a: GO:0072106 ! regulation of ureteric bud formation is_a: GO:0110110 ! positive regulation of animal organ morphogenesis is_a: GO:1905278 ! positive regulation of epithelial tube formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060676 ! ureteric bud formation relationship: positively_regulates GO:0060676 ! ureteric bud formation created_by: mah creation_date: 2010-02-12T02:37:28Z [Term] id: GO:0072108 name: positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0003339 ! regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis relationship: positively_regulates GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis created_by: mah creation_date: 2010-02-12T02:45:57Z [Term] id: GO:0072111 name: cell proliferation involved in kidney development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-02-22T10:48:45Z [Term] id: GO:0072114 name: pronephros morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney morphogenesis" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0060993 ! kidney morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002120 ! pronephros relationship: part_of GO:0048793 ! pronephros development relationship: results_in_morphogenesis_of UBERON:0002120 ! pronephros created_by: mah creation_date: 2010-02-22T11:12:15Z [Term] id: GO:0072116 name: pronephros formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney formation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048645 ! animal organ formation is_a: GO:0072003 ! kidney rudiment formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002120 ! pronephros relationship: part_of GO:0072114 ! pronephros morphogenesis relationship: results_in_formation_of UBERON:0002120 ! pronephros created_by: mah creation_date: 2010-02-22T11:16:26Z [Term] id: GO:0072120 name: pronephros maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." [GOC:mtg_kidney_jan10] synonym: "pronephric kidney maturation" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048799 ! animal organ maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of UBERON:0002120 ! pronephros relationship: part_of GO:0048793 ! pronephros development relationship: results_in_maturation_of UBERON:0002120 ! pronephros created_by: mah creation_date: 2010-02-22T11:25:48Z [Term] id: GO:0072127 name: renal capsule development namespace: biological_process def: "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0061448 ! connective tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002015 ! kidney capsule relationship: part_of GO:0001822 ! kidney development relationship: results_in_development_of UBERON:0002015 ! kidney capsule created_by: mah creation_date: 2010-02-22T02:02:55Z [Term] id: GO:0072128 name: renal capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002015 ! kidney capsule relationship: part_of GO:0072127 ! renal capsule development relationship: results_in_morphogenesis_of UBERON:0002015 ! kidney capsule created_by: mah creation_date: 2010-02-22T02:06:19Z [Term] id: GO:0072129 name: renal capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." [GOC:mtg_kidney_jan10] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0002015 ! kidney capsule relationship: part_of GO:0072128 ! renal capsule morphogenesis relationship: results_in_formation_of UBERON:0002015 ! kidney capsule created_by: mah creation_date: 2010-02-22T02:08:14Z [Term] id: GO:0072131 name: kidney mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072132 ! mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003918 ! kidney mesenchyme relationship: part_of GO:0072074 ! kidney mesenchyme development relationship: results_in_morphogenesis_of UBERON:0003918 ! kidney mesenchyme created_by: mah creation_date: 2010-02-22T02:16:43Z [Term] id: GO:0072132 name: mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." [GOC:mtg_kidney_jan10] is_a: GO:0048729 ! tissue morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003104 ! mesenchyme relationship: part_of GO:0009887 ! animal organ morphogenesis relationship: part_of GO:0060485 ! mesenchyme development relationship: results_in_morphogenesis_of UBERON:0003104 ! mesenchyme created_by: mah creation_date: 2010-02-22T02:17:15Z [Term] id: GO:0072133 name: metanephric mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003220 ! metanephric mesenchyme relationship: part_of GO:0072075 ! metanephric mesenchyme development relationship: results_in_morphogenesis_of UBERON:0003220 ! metanephric mesenchyme created_by: mah creation_date: 2010-02-22T02:20:14Z [Term] id: GO:0072134 name: nephrogenic mesenchyme morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GOC:mtg_kidney_jan10] is_a: GO:0072131 ! kidney mesenchyme morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0004208 ! nephrogenic mesenchyme relationship: part_of GO:0072076 ! nephrogenic mesenchyme development relationship: results_in_morphogenesis_of UBERON:0004208 ! nephrogenic mesenchyme created_by: mah creation_date: 2010-02-22T02:21:16Z [Term] id: GO:0072138 name: mesenchymal cell proliferation involved in ureteric bud development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development." [GOC:mtg_kidney_jan10] synonym: "ureteric bud mesenchymal cell proliferation" BROAD [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation is_a: GO:0061209 ! cell proliferation involved in mesonephros development intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0001657 ! ureteric bud development relationship: part_of GO:0001657 ! ureteric bud development created_by: mah creation_date: 2010-02-22T02:40:38Z [Term] id: GO:0072141 name: renal interstitial fibroblast development namespace: biological_process def: "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] synonym: "kidney interstitial cell development" EXACT [GOC:mtg_kidney_jan10] is_a: GO:0048468 ! cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:1000692 ! kidney interstitial fibroblast relationship: part_of GO:0072071 ! kidney interstitial fibroblast differentiation relationship: results_in_development_of CL:1000692 ! kidney interstitial fibroblast created_by: mah creation_date: 2010-02-24T01:39:05Z [Term] id: GO:0072155 name: epithelial cell migration involved in nephron tubule morphogenesis namespace: biological_process def: "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0010631 ! epithelial cell migration is_a: GO:0035787 ! cell migration involved in kidney development intersection_of: GO:0010631 ! epithelial cell migration intersection_of: part_of GO:0072078 ! nephron tubule morphogenesis relationship: part_of GO:0072078 ! nephron tubule morphogenesis created_by: mah creation_date: 2010-02-24T02:21:25Z [Term] id: GO:0072160 name: nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0035850 ! epithelial cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000494 ! nephron tubule epithelial cell relationship: part_of GO:0072080 ! nephron tubule development relationship: results_in_acquisition_of_features_of CL:1000494 ! nephron tubule epithelial cell created_by: mah creation_date: 2010-02-24T02:40:11Z [Term] id: GO:0072161 name: mesenchymal cell differentiation involved in kidney development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development is_a: GO:2001012 ! mesenchymal cell differentiation involved in renal system development intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0001822 ! kidney development relationship: part_of GO:0072074 ! kidney mesenchyme development created_by: mah creation_date: 2010-02-26T01:31:49Z [Term] id: GO:0072163 name: mesonephric epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005103 ! mesonephric epithelium relationship: part_of GO:0001823 ! mesonephros development relationship: results_in_development_of UBERON:0005103 ! mesonephric epithelium created_by: mah creation_date: 2010-02-26T01:40:43Z [Term] id: GO:0072164 name: mesonephric tubule development namespace: biological_process def: "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072163 ! mesonephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000083 ! mesonephric tubule relationship: results_in_development_of UBERON:0000083 ! mesonephric tubule created_by: mah creation_date: 2010-02-26T01:45:58Z [Term] id: GO:0072170 name: metanephric tubule development namespace: biological_process def: "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005106 ! metanephric tubule relationship: results_in_development_of UBERON:0005106 ! metanephric tubule created_by: mah creation_date: 2010-02-26T01:58:18Z [Term] id: GO:0072171 name: mesonephric tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000083 ! mesonephric tubule relationship: part_of GO:0072164 ! mesonephric tubule development relationship: results_in_morphogenesis_of UBERON:0000083 ! mesonephric tubule created_by: mah creation_date: 2010-02-26T02:02:13Z [Term] id: GO:0072172 name: mesonephric tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0000083 ! mesonephric tubule relationship: part_of GO:0072171 ! mesonephric tubule morphogenesis relationship: results_in_formation_of UBERON:0000083 ! mesonephric tubule created_by: mah creation_date: 2010-02-26T02:02:37Z [Term] id: GO:0072173 name: metanephric tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005106 ! metanephric tubule relationship: part_of GO:0072170 ! metanephric tubule development relationship: results_in_morphogenesis_of UBERON:0005106 ! metanephric tubule created_by: mah creation_date: 2010-02-26T02:06:42Z [Term] id: GO:0072174 name: metanephric tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric tubule." [GOC:mtg_kidney_jan10] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005106 ! metanephric tubule relationship: part_of GO:0072173 ! metanephric tubule morphogenesis relationship: results_in_formation_of UBERON:0005106 ! metanephric tubule created_by: mah creation_date: 2010-02-26T02:07:41Z [Term] id: GO:0072175 name: epithelial tube formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an epithelial tube." [GOC:mtg_kidney_jan10] is_a: GO:0035148 ! tube formation intersection_of: GO:0035148 ! tube formation intersection_of: results_in_formation_of UBERON:0003914 ! epithelial tube relationship: part_of GO:0060562 ! epithelial tube morphogenesis relationship: results_in_formation_of UBERON:0003914 ! epithelial tube property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI created_by: mah creation_date: 2010-02-26T02:15:40Z [Term] id: GO:0072176 name: nephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009201 ! nephric duct relationship: results_in_development_of UBERON:0009201 ! nephric duct created_by: mah creation_date: 2010-02-26T02:27:31Z [Term] id: GO:0072177 name: mesonephric duct development namespace: biological_process def: "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct development" EXACT [GOC:dph] is_a: GO:0072164 ! mesonephric tubule development is_a: GO:0072176 ! nephric duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003074 ! mesonephric duct relationship: results_in_development_of UBERON:0003074 ! mesonephric duct created_by: mah creation_date: 2010-02-26T02:32:22Z [Term] id: GO:0072178 name: nephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0060562 ! epithelial tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0009201 ! nephric duct relationship: part_of GO:0072176 ! nephric duct development relationship: results_in_morphogenesis_of UBERON:0009201 ! nephric duct created_by: mah creation_date: 2010-02-26T02:35:29Z [Term] id: GO:0072179 name: nephric duct formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0009201 ! nephric duct relationship: part_of GO:0072178 ! nephric duct morphogenesis relationship: results_in_formation_of UBERON:0009201 ! nephric duct created_by: mah creation_date: 2010-02-26T02:35:55Z [Term] id: GO:0072180 name: mesonephric duct morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct morphogenesis" RELATED [GOC:dph] is_a: GO:0072171 ! mesonephric tubule morphogenesis is_a: GO:0072178 ! nephric duct morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003074 ! mesonephric duct relationship: part_of GO:0072177 ! mesonephric duct development relationship: results_in_morphogenesis_of UBERON:0003074 ! mesonephric duct created_by: mah creation_date: 2010-02-26T02:37:13Z [Term] id: GO:0072181 name: mesonephric duct formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros." [GOC:mtg_kidney_jan10] synonym: "Wolffian duct formation" EXACT [GOC:dph] is_a: GO:0072172 ! mesonephric tubule formation is_a: GO:0072179 ! nephric duct formation is_a: GO:0072180 ! mesonephric duct morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0003074 ! mesonephric duct relationship: results_in_formation_of UBERON:0003074 ! mesonephric duct created_by: mah creation_date: 2010-02-26T02:38:03Z [Term] id: GO:0072182 name: regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072160 ! nephron tubule epithelial cell differentiation relationship: regulates GO:0072160 ! nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-02-26T02:45:09Z [Term] id: GO:0072183 name: negative regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:0090185 ! negative regulation of kidney development is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation relationship: negatively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-02-26T02:47:25Z [Term] id: GO:0072189 name: ureter development namespace: biological_process def: "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." [GOC:mtg_kidney_jan10] is_a: GO:0035295 ! tube development is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000056 ! ureter relationship: part_of GO:0072001 ! renal system development relationship: results_in_development_of UBERON:0000056 ! ureter created_by: mah creation_date: 2010-03-01T01:44:14Z [Term] id: GO:0072191 name: ureter smooth muscle development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0009919 ! ureter smooth muscle relationship: part_of GO:0072189 ! ureter development relationship: results_in_development_of UBERON:0009919 ! ureter smooth muscle created_by: mah creation_date: 2010-03-01T01:48:53Z [Term] id: GO:0072193 name: ureter smooth muscle cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter." [GOC:mtg_kidney_jan10] is_a: GO:0051145 ! smooth muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000979 ! ureter smooth muscle cell relationship: part_of GO:0072191 ! ureter smooth muscle development relationship: results_in_acquisition_of_features_of CL:1000979 ! ureter smooth muscle cell created_by: mah creation_date: 2010-03-01T01:55:01Z [Term] id: GO:0072194 name: kidney smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0048745 ! smooth muscle tissue development relationship: part_of GO:0001822 ! kidney development created_by: mah creation_date: 2010-03-01T02:05:30Z [Term] id: GO:0072197 name: ureter morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder." [GOC:mtg_kidney_jan10] is_a: GO:0009887 ! animal organ morphogenesis is_a: GO:0035239 ! tube morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000056 ! ureter relationship: part_of GO:0072189 ! ureter development relationship: results_in_morphogenesis_of UBERON:0000056 ! ureter created_by: mah creation_date: 2010-03-01T02:24:55Z [Term] id: GO:0072198 name: mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development." [GOC:mtg_kidney_jan10] synonym: "ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0010463 ! mesenchymal cell proliferation intersection_of: GO:0010463 ! mesenchymal cell proliferation intersection_of: part_of GO:0072189 ! ureter development relationship: part_of GO:0072189 ! ureter development created_by: mah creation_date: 2010-03-01T03:24:41Z [Term] id: GO:0072199 name: regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] synonym: "regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development relationship: regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development created_by: mah creation_date: 2010-03-01T03:38:13Z [Term] id: GO:0072200 name: negative regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] synonym: "negative regulation of ureter mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] synonym: "negative regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development relationship: negatively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development created_by: mah creation_date: 2010-03-01T03:42:31Z [Term] id: GO:0072201 name: negative regulation of mesenchymal cell proliferation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." [GOC:mtg_kidney_jan10] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010463 ! mesenchymal cell proliferation relationship: negatively_regulates GO:0010463 ! mesenchymal cell proliferation created_by: mah creation_date: 2010-03-01T03:43:29Z [Term] id: GO:0072202 name: cell differentiation involved in metanephros development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state." [GOC:mah, GOC:mtg_kidney_jan10] is_a: GO:0061005 ! cell differentiation involved in kidney development intersection_of: GO:0030154 ! cell differentiation intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:40:14Z [Term] id: GO:0072203 name: cell proliferation involved in metanephros development namespace: biological_process def: "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072111 ! cell proliferation involved in kidney development intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:42:27Z [Term] id: GO:0072204 name: cell-cell signaling involved in metanephros development namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." [GOC:mtg_kidney_jan10] synonym: "cell-cell signalling involved in metanephros development" EXACT [GOC:mah] is_a: GO:0060995 ! cell-cell signaling involved in kidney development intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T10:54:36Z [Term] id: GO:0072205 name: metanephric collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." [GOC:mtg_kidney_jan10] is_a: GO:0072044 ! collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004737 ! metanephric collecting duct relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0004737 ! metanephric collecting duct created_by: mah creation_date: 2010-03-18T11:15:37Z [Term] id: GO:0072207 name: metanephric epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." [GOC:mtg_kidney_jan10] is_a: GO:0072073 ! kidney epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005108 ! metanephric epithelium relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005108 ! metanephric epithelium created_by: mah creation_date: 2010-03-18T11:50:37Z [Term] id: GO:0072208 name: metanephric smooth muscle tissue development namespace: biological_process def: "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure." [GOC:mtg_kidney_jan10] is_a: GO:0072194 ! kidney smooth muscle tissue development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005109 ! metanephric smooth muscle tissue relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005109 ! metanephric smooth muscle tissue created_by: mah creation_date: 2010-03-18T11:51:59Z [Term] id: GO:0072210 name: metanephric nephron development namespace: biological_process def: "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." [GOC:mtg_kidney_jan10] is_a: GO:0072006 ! nephron development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005110 ! metanephric nephron relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005110 ! metanephric nephron created_by: mah creation_date: 2010-03-18T12:52:57Z [Term] id: GO:0072213 name: metanephric capsule development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072127 ! renal capsule development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005137 ! metanephric capsule relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005137 ! metanephric capsule created_by: mah creation_date: 2010-03-18T01:25:19Z [Term] id: GO:0072214 name: metanephric cortex development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0060485 ! mesenchyme development is_a: GO:0072055 ! renal cortex development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005113 ! metanephric cortex mesenchyme relationship: part_of GO:0001656 ! metanephros development relationship: results_in_development_of UBERON:0005113 ! metanephric cortex mesenchyme created_by: mah creation_date: 2010-03-18T01:29:49Z [Term] id: GO:0072215 name: regulation of metanephros development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001656 ! metanephros development relationship: regulates GO:0001656 ! metanephros development [Term] id: GO:0072216 name: positive regulation of metanephros development namespace: biological_process def: "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090184 ! positive regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001656 ! metanephros development relationship: positively_regulates GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T01:40:12Z [Term] id: GO:0072217 name: negative regulation of metanephros development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:mtg_kidney_jan10] is_a: GO:0072215 ! regulation of metanephros development is_a: GO:0090185 ! negative regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001656 ! metanephros development relationship: negatively_regulates GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-18T01:45:48Z [Term] id: GO:0072219 name: metanephric cortical collecting duct development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex." [GOC:mtg_kidney_jan10] is_a: GO:0072059 ! cortical collecting duct development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005115 ! metanephric cortical collecting duct relationship: results_in_development_of UBERON:0005115 ! metanephric cortical collecting duct created_by: mah creation_date: 2010-03-18T03:34:52Z [Term] id: GO:0072234 name: metanephric nephron tubule development namespace: biological_process def: "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072080 ! nephron tubule development is_a: GO:0072170 ! metanephric tubule development is_a: GO:0072243 ! metanephric nephron epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005146 ! metanephric nephron tubule relationship: results_in_development_of UBERON:0005146 ! metanephric nephron tubule created_by: mah creation_date: 2010-03-18T03:41:23Z [Term] id: GO:0072243 name: metanephric nephron epithelium development namespace: biological_process def: "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072009 ! nephron epithelium development is_a: GO:0072207 ! metanephric epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005134 ! metanephric nephron epithelium relationship: results_in_development_of UBERON:0005134 ! metanephric nephron epithelium created_by: mah creation_date: 2010-03-19T03:29:49Z [Term] id: GO:0072257 name: metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10] is_a: GO:0072160 ! nephron tubule epithelial cell differentiation is_a: GO:0072202 ! cell differentiation involved in metanephros development intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:1000123 ! metanephric nephron tubule epithelial cell relationship: part_of GO:0072234 ! metanephric nephron tubule development relationship: results_in_acquisition_of_features_of CL:1000123 ! metanephric nephron tubule epithelial cell created_by: mah creation_date: 2010-03-19T04:11:02Z [Term] id: GO:0072265 name: metanephric capsule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072128 ! renal capsule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005137 ! metanephric capsule relationship: part_of GO:0072213 ! metanephric capsule development relationship: results_in_morphogenesis_of UBERON:0005137 ! metanephric capsule created_by: mah creation_date: 2010-03-30T02:54:49Z [Term] id: GO:0072266 name: metanephric capsule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." [GOC:mtg_kidney_jan10] is_a: GO:0072129 ! renal capsule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005137 ! metanephric capsule relationship: part_of GO:0072265 ! metanephric capsule morphogenesis relationship: results_in_formation_of UBERON:0005137 ! metanephric capsule created_by: mah creation_date: 2010-03-30T02:56:35Z [Term] id: GO:0072268 name: pattern specification involved in metanephros development namespace: biological_process def: "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate." [GOC:mtg_kidney_jan10] synonym: "metanephros pattern formation" RELATED [GOC:mtg_kidney_jan10] synonym: "metanephros pattern specification" EXACT [GOC:mtg_kidney_jan10] synonym: "pattern formation involved in metanephros development" RELATED [GOC:mtg_kidney_jan10] is_a: GO:0061004 ! pattern specification involved in kidney development intersection_of: GO:0007389 ! pattern specification process intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: mah creation_date: 2010-03-30T03:06:30Z [Term] id: GO:0072273 name: metanephric nephron morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072028 ! nephron morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005110 ! metanephric nephron relationship: part_of GO:0003338 ! metanephros morphogenesis relationship: part_of GO:0072210 ! metanephric nephron development relationship: results_in_morphogenesis_of UBERON:0005110 ! metanephric nephron created_by: mah creation_date: 2010-03-30T03:33:19Z [Term] id: GO:0072282 name: metanephric nephron tubule morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072078 ! nephron tubule morphogenesis is_a: GO:0072173 ! metanephric tubule morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005146 ! metanephric nephron tubule relationship: part_of GO:0072234 ! metanephric nephron tubule development relationship: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0005146 ! metanephric nephron tubule created_by: mah creation_date: 2010-04-01T03:25:11Z [Term] id: GO:0072283 name: metanephric renal vesicle morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072077 ! renal vesicle morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005147 ! metanephric renal vesicle relationship: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: results_in_morphogenesis_of UBERON:0005147 ! metanephric renal vesicle created_by: mah creation_date: 2010-04-01T03:28:00Z [Term] id: GO:0072285 name: mesenchymal to epithelial transition involved in metanephric renal vesicle formation namespace: biological_process def: "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle." [GOC:mtg_kidney_jan10] is_a: GO:0003337 ! mesenchymal to epithelial transition involved in metanephros morphogenesis is_a: GO:0072036 ! mesenchymal to epithelial transition involved in renal vesicle formation intersection_of: GO:0060231 ! mesenchymal to epithelial transition intersection_of: part_of GO:0072093 ! metanephric renal vesicle formation relationship: part_of GO:0072093 ! metanephric renal vesicle formation created_by: mah creation_date: 2010-04-01T03:43:31Z [Term] id: GO:0072289 name: metanephric nephron tubule formation namespace: biological_process def: "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros." [GOC:mtg_kidney_jan10] is_a: GO:0072079 ! nephron tubule formation is_a: GO:0072174 ! metanephric tubule formation intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0005146 ! metanephric nephron tubule relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis relationship: results_in_formation_of UBERON:0005146 ! metanephric nephron tubule created_by: mah creation_date: 2010-04-09T03:47:44Z [Term] id: GO:0072290 name: epithelial cell migration involved in metanephric nephron tubule morphogenesis namespace: biological_process def: "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." [GOC:mtg_kidney_jan10] is_a: GO:0035788 ! cell migration involved in metanephros development is_a: GO:0072155 ! epithelial cell migration involved in nephron tubule morphogenesis intersection_of: GO:0010631 ! epithelial cell migration intersection_of: part_of GO:0072282 ! metanephric nephron tubule morphogenesis relationship: part_of GO:0072282 ! metanephric nephron tubule morphogenesis created_by: mah creation_date: 2010-04-09T03:52:29Z [Term] id: GO:0072304 name: regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072039 ! regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072305 name: negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072040 ! negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900212 ! negative regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: negatively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: negatively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072306 name: positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10] synonym: "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" NARROW [] synonym: "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" EXACT [] is_a: GO:0072041 ! positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis is_a: GO:0072304 ! regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis is_a: GO:1900213 ! positive regulation of mesenchymal cell apoptotic process involved in metanephros development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis relationship: positively_regulates GO:0072309 ! mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis relationship: positively_regulates GO:1901147 ! mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072307 name: regulation of metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation relationship: regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072308 name: negative regulation of metanephric nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." [GOC:mtg_kidney_jan10] is_a: GO:0072183 ! negative regulation of nephron tubule epithelial cell differentiation is_a: GO:0072307 ! regulation of metanephric nephron tubule epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation relationship: negatively_regulates GO:0072257 ! metanephric nephron tubule epithelial cell differentiation created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072309 name: mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis namespace: biological_process def: "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." [GOC:mtg_kidney_jan10] is_a: GO:0072038 ! mesenchymal stem cell maintenance involved in nephron morphogenesis relationship: part_of GO:0072273 ! metanephric nephron morphogenesis created_by: mah creation_date: 2010-04-09T05:03:41Z [Term] id: GO:0072329 name: monocarboxylic acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046395 ! carboxylic acid catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_input CHEBI:35757 ! monocarboxylic acid anion created_by: mah creation_date: 2010-11-02T04:41:55Z [Term] id: GO:0072330 name: monocarboxylic acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." [GOC:mah] synonym: "monocarboxylic acid anabolism" EXACT [GOC:mah] synonym: "monocarboxylic acid biosynthesis" EXACT [GOC:mah] synonym: "monocarboxylic acid formation" EXACT [GOC:mah] synonym: "monocarboxylic acid synthesis" EXACT [GOC:mah] is_a: GO:0032787 ! monocarboxylic acid metabolic process is_a: GO:0046394 ! carboxylic acid biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35757 ! monocarboxylic acid anion relationship: has_primary_output CHEBI:35757 ! monocarboxylic acid anion created_by: mah creation_date: 2010-11-02T04:51:32Z [Term] id: GO:0072348 name: sulfur compound transport namespace: biological_process def: "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:mah] synonym: "sulfur-containing compound transport" EXACT [GOC:mah] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity created_by: mah creation_date: 2010-11-11T11:43:56Z [Term] id: GO:0072359 name: circulatory system development namespace: biological_process alt_id: GO:0072358 def: "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." [GOC:mah, UBERON:0001009] subset: goslim_drosophila synonym: "cardiovascular system development" NARROW [] is_a: GO:0048731 ! system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001009 ! circulatory system relationship: results_in_development_of UBERON:0001009 ! circulatory system created_by: mah creation_date: 2010-11-16T11:27:39Z [Term] id: GO:0072360 name: vascular cord development namespace: biological_process def: "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." [GOC:mah, PMID:7084422, ZFA:0005077] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006965 ! vascular cord relationship: part_of GO:0072359 ! circulatory system development relationship: results_in_development_of UBERON:0006965 ! vascular cord created_by: mah creation_date: 2010-11-16T11:46:55Z [Term] id: GO:0072384 name: organelle transport along microtubule namespace: biological_process def: "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." [GOC:mah] synonym: "microtubule-based organelle localization" EXACT [GOC:rl] is_a: GO:0010970 ! transport along microtubule is_a: GO:0051656 ! establishment of organelle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0043226 ! organelle intersection_of: results_in_transport_along GO:0005874 ! microtubule created_by: mah creation_date: 2010-12-01T04:59:11Z [Term] id: GO:0072488 name: ammonium transmembrane transport namespace: biological_process alt_id: GO:0015696 def: "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "ammonia transport" BROAD [] synonym: "ammonium membrane transport" EXACT [] synonym: "ammonium transport" BROAD [] is_a: GO:0071705 ! nitrogen compound transport is_a: GO:0098662 ! inorganic cation transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:28938 ! ammonium intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:28938 ! ammonium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22228" xsd:anyURI created_by: mah creation_date: 2010-12-10T10:29:57Z [Term] id: GO:0072520 name: seminiferous tubule development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa." [GOC:BHF, GOC:mah, UBERON:0001343] is_a: GO:0035295 ! tube development is_a: GO:0048608 ! reproductive structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001343 ! seminiferous tubule of testis relationship: part_of GO:0008584 ! male gonad development relationship: results_in_development_of UBERON:0001343 ! seminiferous tubule of testis created_by: mah creation_date: 2011-01-04T12:50:36Z [Term] id: GO:0072537 name: fibroblast activation namespace: biological_process def: "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." [CL:0000057, GOC:BHF, GOC:mah] is_a: GO:0001775 ! cell activation intersection_of: GO:0001775 ! cell activation intersection_of: has_input CL:0000057 ! fibroblast relationship: has_input CL:0000057 ! fibroblast created_by: mah creation_date: 2011-01-14T04:35:08Z [Term] id: GO:0072560 name: type B pancreatic cell maturation namespace: biological_process def: "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF] comment: These processes continue to 60 DPA in Gossypium spp. synonym: "pancreatic B cell maturation" EXACT [CL:0000169, GOC:mah] synonym: "pancreatic beta cell maturation" EXACT [CL:0000169, GOC:mah] is_a: GO:0002071 ! glandular epithelial cell maturation intersection_of: GO:0021700 ! developmental maturation intersection_of: results_in_maturation_of CL:0000169 ! type B pancreatic cell relationship: part_of GO:0003323 ! type B pancreatic cell development relationship: results_in_maturation_of CL:0000169 ! type B pancreatic cell created_by: mah creation_date: 2011-01-27T01:57:14Z [Term] id: GO:0072575 name: epithelial cell proliferation involved in liver morphogenesis namespace: biological_process def: "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver." [GOC:BHF, GOC:mah] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0072576 ! liver morphogenesis relationship: part_of GO:0072576 ! liver morphogenesis created_by: mah creation_date: 2011-02-02T03:37:50Z [Term] id: GO:0072576 name: liver morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the liver are generated and organized." [GOC:mah] is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002107 ! liver relationship: part_of GO:0001889 ! liver development relationship: results_in_morphogenesis_of UBERON:0002107 ! liver created_by: mah creation_date: 2011-02-02T03:41:30Z [Term] id: GO:0072577 name: endothelial cell apoptotic process namespace: biological_process def: "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." [CL:0000115, GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "apoptosis of endothelial cells" EXACT [GOC:mah] synonym: "endothelial cell apoptosis" NARROW [] synonym: "endothelial cell programmed cell death by apoptosis" EXACT [GOC:mah] synonym: "killing of endothelial cells" EXACT [GOC:mah] synonym: "programmed cell death of endothelial cells by apoptosis" EXACT [GOC:mah] synonym: "programmed cell death, endothelial cells" EXACT [GOC:mah] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000115 ! endothelial cell relationship: occurs_in CL:0000115 ! endothelial cell created_by: mah creation_date: 2011-02-02T03:56:24Z [Term] id: GO:0072592 name: oxygen metabolic process namespace: biological_process def: "The chemical reactions and pathways involving diatomic oxygen (O2)." [GOC:mah] synonym: "diatomic oxygen metabolic process" EXACT [CHEBI:33263] synonym: "oxygen metabolism" EXACT [GOC:mah] is_a: GO:0044237 ! cellular metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:15379 ! dioxygen relationship: has_primary_input_or_output CHEBI:15379 ! dioxygen created_by: mah creation_date: 2011-02-11T10:46:51Z [Term] id: GO:0072594 name: establishment of protein localization to organelle namespace: biological_process def: "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." [GOC:mah] synonym: "establishment of protein localisation to organelle" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle is_a: GO:0045184 ! establishment of protein localization intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0043226 ! organelle created_by: mah creation_date: 2011-02-14T01:56:51Z [Term] id: GO:0072657 name: protein localization to membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a specific location in a membrane." [GOC:mah] subset: prokaryote_subset synonym: "protein localisation in membrane" EXACT [GOC:mah] synonym: "protein localization in membrane" EXACT [] is_a: GO:0008104 ! protein localization is_a: GO:0051668 ! localization within membrane intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0016020 ! membrane created_by: mah creation_date: 2011-02-14T02:35:18Z [Term] id: GO:0072659 name: protein localization to plasma membrane namespace: biological_process alt_id: GO:0072661 alt_id: GO:0090002 def: "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." [GOC:mah] subset: goslim_generic subset: goslim_pombe synonym: "protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "protein localization in plasma membrane" RELATED [] synonym: "protein targeting to plasma membrane" RELATED [] synonym: "protein-plasma membrane targeting" RELATED [GOC:mah] is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure relationship: has_target_end_location GO:0005886 ! plasma membrane relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: tb creation_date: 2009-07-10T10:29:23Z [Term] id: GO:0072665 name: protein localization to vacuole namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a location in a vacuole." [GOC:ecd] synonym: "protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0033365 ! protein localization to organelle intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005773 ! vacuole relationship: has_target_end_location GO:0005773 ! vacuole created_by: mah creation_date: 2011-02-14T02:55:35Z [Term] id: GO:0072666 name: establishment of protein localization to vacuole namespace: biological_process def: "The directed movement of a protein to a specific location in a vacuole." [GOC:mah] synonym: "establishment of protein localisation to vacuole" EXACT [GOC:mah] is_a: GO:0072594 ! establishment of protein localization to organelle is_a: GO:0072665 ! protein localization to vacuole intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0005773 ! vacuole created_by: mah creation_date: 2011-02-14T02:56:29Z [Term] id: GO:0072676 name: lymphocyte migration namespace: biological_process def: "The movement of a lymphocyte within or between different tissues and organs of the body." [CL:0000542, GOC:BHF, GOC:mah] is_a: GO:0071674 ! mononuclear cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000542 ! lymphocyte relationship: results_in_movement_of CL:0000542 ! lymphocyte created_by: mah creation_date: 2011-02-22T03:38:12Z [Term] id: GO:0072678 name: T cell migration namespace: biological_process def: "The movement of a T cell within or between different tissues and organs of the body." [CL:0000084, GOC:BHF, GOC:mah] synonym: "T lymphocyte migration" EXACT [CL:0000084] synonym: "T-cell migration" EXACT [CL:0000084] synonym: "T-lymphocyte migration" EXACT [CL:0000084] is_a: GO:0072676 ! lymphocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000084 ! T cell relationship: results_in_movement_of CL:0000084 ! T cell created_by: mah creation_date: 2011-02-22T03:40:40Z [Term] id: GO:0072697 name: protein localization to cell cortex namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the cell cortex." [GOC:mah] synonym: "protein localisation to cell cortex" EXACT [GOC:mah] is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005938 ! cell cortex relationship: has_target_end_location GO:0005938 ! cell cortex created_by: mah creation_date: 2012-04-11T01:16:33Z [Term] id: GO:0072698 name: protein localization to microtubule cytoskeleton namespace: biological_process def: "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." [GOC:mah] synonym: "protein localisation to microtubule cytoskeleton" EXACT [GOC:mah] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0015630 ! microtubule cytoskeleton relationship: has_target_end_location GO:0015630 ! microtubule cytoskeleton created_by: mah creation_date: 2012-04-11T01:19:35Z [Term] id: GO:0080090 name: regulation of primary metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." [PMID:19211694] is_a: GO:0019222 ! regulation of metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044238 ! primary metabolic process relationship: regulates GO:0044238 ! primary metabolic process created_by: dhl creation_date: 2009-04-22T04:30:52Z [Term] id: GO:0080134 name: regulation of response to stress namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." [GOC:dhl] comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. subset: gocheck_do_not_manually_annotate is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006950 ! response to stress relationship: regulates GO:0006950 ! response to stress created_by: dhl creation_date: 2009-05-06T04:51:28Z [Term] id: GO:0080154 name: regulation of fertilization namespace: biological_process def: "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." [GOC:DHL, PMID:20478994] is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009566 ! fertilization relationship: regulates GO:0009566 ! fertilization created_by: dhl creation_date: 2010-09-01T03:44:27Z [Term] id: GO:0085029 name: extracellular matrix assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of the extracellular matrix." [GOC:jl] is_a: GO:0022607 ! cellular component assembly is_a: GO:0030198 ! extracellular matrix organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0031012 ! extracellular matrix relationship: results_in_assembly_of GO:0031012 ! extracellular matrix created_by: jl creation_date: 2010-07-14T12:52:49Z [Term] id: GO:0086001 name: cardiac muscle cell action potential namespace: biological_process def: "An action potential that occurs in a cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0001508 ! action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:0000746 ! cardiac muscle cell relationship: occurs_in CL:0000746 ! cardiac muscle cell created_by: tb creation_date: 2011-11-10T07:45:11Z [Term] id: GO:0086015 name: SA node cell action potential namespace: biological_process def: "An action potential that occurs in a sinoatrial node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell action potential" EXACT [] synonym: "SAN cardiac muscle cell action potential" EXACT [] synonym: "sinoatrial node cardiac muscle cell action potential" EXACT [] synonym: "sinus node cardiac muscle cell action potential" NARROW [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:1000409 ! myocyte of sinoatrial node relationship: occurs_in CL:1000409 ! myocyte of sinoatrial node relationship: part_of GO:0086018 ! SA node cell to atrial cardiac muscle cell signaling created_by: tb creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0086016 name: AV node cell action potential namespace: biological_process def: "An action potential that occurs in an atrioventricular node cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:1000410 ! myocyte of atrioventricular node relationship: occurs_in CL:1000410 ! myocyte of atrioventricular node relationship: part_of GO:0086027 ! AV node cell to bundle of His cell signaling created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086017 name: Purkinje myocyte action potential namespace: biological_process def: "An action potential that occurs in a Purkinje myocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086001 ! cardiac muscle cell action potential intersection_of: GO:0001508 ! action potential intersection_of: occurs_in CL:0002068 ! Purkinje myocyte relationship: occurs_in CL:0002068 ! Purkinje myocyte relationship: part_of GO:0086029 ! Purkinje myocyte to ventricular cardiac muscle cell signaling created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0086018 name: SA node cell to atrial cardiac muscle cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell signalling" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling" EXACT [] synonym: "sinus node cardiomyocyte to atrial cardiomyocyte signalling" NARROW [] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086070 ! SA node cell to atrial cardiac muscle cell communication created_by: tb creation_date: 2011-11-10T09:15:01Z [Term] id: GO:0086019 name: cell-cell signaling involved in cardiac conduction namespace: biological_process def: "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "cell-cell signalling involved in cardiac conduction" EXACT [GOC:mah] is_a: GO:0007267 ! cell-cell signaling is_a: GO:0086065 ! cell communication involved in cardiac conduction intersection_of: GO:0007267 ! cell-cell signaling intersection_of: part_of GO:0061337 ! cardiac conduction created_by: dph creation_date: 2011-11-16T03:43:52Z [Term] id: GO:0086027 name: AV node cell to bundle of His cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node to bundle of His cell signaling" EXACT [] synonym: "AV node cell to bundle of His cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086067 ! AV node cell to bundle of His cell communication created_by: tb creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086029 name: Purkinje myocyte to ventricular cardiac muscle cell signaling namespace: biological_process def: "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "Purkinje myocyte to ventricular cardiac muscle cell signalling" EXACT [GOC:mah] is_a: GO:0086019 ! cell-cell signaling involved in cardiac conduction is_a: GO:0086068 ! Purkinje myocyte to ventricular cardiac muscle cell communication created_by: tb creation_date: 2011-11-11T02:02:14Z [Term] id: GO:0086065 name: cell communication involved in cardiac conduction namespace: biological_process def: "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0007154 ! cell communication intersection_of: GO:0007154 ! cell communication intersection_of: part_of GO:0061337 ! cardiac conduction relationship: part_of GO:0061337 ! cardiac conduction created_by: dph creation_date: 2011-11-22T08:57:02Z [Term] id: GO:0086067 name: AV node cell to bundle of His cell communication namespace: biological_process def: "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "atrioventricular node cell to bundle of His cell communication" EXACT [] is_a: GO:0086065 ! cell communication involved in cardiac conduction created_by: dph creation_date: 2011-11-22T09:11:44Z [Term] id: GO:0086068 name: Purkinje myocyte to ventricular cardiac muscle cell communication namespace: biological_process def: "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0086065 ! cell communication involved in cardiac conduction created_by: dph creation_date: 2011-11-22T09:14:49Z [Term] id: GO:0086070 name: SA node cell to atrial cardiac muscle cell communication namespace: biological_process def: "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "SA node cardiac muscle cell to atrial cardiac muscle cell communication" EXACT [] synonym: "SA node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "SAN cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication" EXACT [] synonym: "sinus node cardiomyocyte to atrial cardiomyocyte communication" NARROW [] is_a: GO:0086065 ! cell communication involved in cardiac conduction created_by: dph creation_date: 2011-11-22T09:32:45Z [Term] id: GO:0090009 name: primitive streak formation namespace: biological_process def: "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." [GOC:dph, GOC:sdb_2009, GOC:tb] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0004341 ! primitive streak relationship: part_of GO:0001702 ! gastrulation with mouth forming second relationship: part_of GO:0009948 ! anterior/posterior axis specification relationship: results_in_formation_of UBERON:0004341 ! primitive streak created_by: tb creation_date: 2009-07-29T10:31:31Z [Term] id: GO:0090063 name: positive regulation of microtubule nucleation namespace: biological_process def: "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." [GOC:dph, GOC:tb] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031116 ! positive regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007020 ! microtubule nucleation relationship: positively_regulates GO:0007020 ! microtubule nucleation created_by: tb creation_date: 2009-08-12T11:33:09Z [Term] id: GO:0090068 name: positive regulation of cell cycle process namespace: biological_process def: "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." [GOC:dph, GOC:tb] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0045787 ! positive regulation of cell cycle intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022402 ! cell cycle process relationship: positively_regulates GO:0022402 ! cell cycle process created_by: tb creation_date: 2009-09-09T11:39:52Z [Term] id: GO:0090069 name: regulation of ribosome biogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042254 ! ribosome biogenesis relationship: regulates GO:0042254 ! ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090070 name: positive regulation of ribosome biogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042254 ! ribosome biogenesis relationship: positively_regulates GO:0042254 ! ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090071 name: negative regulation of ribosome biogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." [GOC:dph, GOC:tb] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0090069 ! regulation of ribosome biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042254 ! ribosome biogenesis relationship: negatively_regulates GO:0042254 ! ribosome biogenesis created_by: tb creation_date: 2009-09-11T10:32:17Z [Term] id: GO:0090087 name: regulation of peptide transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:dph, GOC:tb] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015833 ! peptide transport relationship: regulates GO:0015833 ! peptide transport created_by: tb creation_date: 2009-10-23T11:21:38Z [Term] id: GO:0090091 name: positive regulation of extracellular matrix disassembly namespace: biological_process def: "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." [GOC:dph, GOC:tb] is_a: GO:0010715 ! regulation of extracellular matrix disassembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022617 ! extracellular matrix disassembly relationship: positively_regulates GO:0022617 ! extracellular matrix disassembly created_by: tb creation_date: 2009-11-04T10:03:25Z [Term] id: GO:0090130 name: tissue migration namespace: biological_process def: "The process in which the population of cells that make up a tissue undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0032501 ! multicellular organismal process created_by: tb creation_date: 2009-12-07T03:13:55Z [Term] id: GO:0090131 name: mesenchyme migration namespace: biological_process def: "The process in which the population of cells that make up a mesenchyme undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090130 ! tissue migration relationship: part_of GO:0072132 ! mesenchyme morphogenesis created_by: tb creation_date: 2009-12-07T03:15:17Z [Term] id: GO:0090132 name: epithelium migration namespace: biological_process def: "The process in which the population of cells that make up an epithelium undergo directed movement." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0090130 ! tissue migration created_by: tb creation_date: 2009-12-07T03:19:34Z [Term] id: GO:0090138 name: regulation of actin cytoskeleton organization by cell-cell adhesion namespace: biological_process def: "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "regulation of actin cytoskeleton organisation by cell-cell adhesion" EXACT [GOC:mah] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:0098609 ! cell-cell adhesion intersection_of: GO:0098609 ! cell-cell adhesion intersection_of: regulates GO:0030036 ! actin cytoskeleton organization created_by: tb creation_date: 2009-12-08T02:05:00Z [Term] id: GO:0090150 name: establishment of protein localization to membrane namespace: biological_process def: "The directed movement of a protein to a specific location in a membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "establishment of protein localisation in membrane" EXACT [GOC:mah] synonym: "establishment of protein localization in membrane" EXACT [] is_a: GO:0045184 ! establishment of protein localization is_a: GO:0072657 ! protein localization to membrane intersection_of: GO:0045184 ! establishment of protein localization intersection_of: has_target_end_location GO:0016020 ! membrane created_by: tb creation_date: 2009-12-08T03:18:51Z [Term] id: GO:0090162 name: establishment of epithelial cell polarity namespace: biological_process def: "The specification and formation of anisotropic intracellular organization of an epithelial cell." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0030010 ! establishment of cell polarity intersection_of: GO:0030010 ! establishment of cell polarity intersection_of: occurs_in CL:0000066 ! epithelial cell relationship: occurs_in CL:0000066 ! epithelial cell created_by: tb creation_date: 2009-12-08T08:58:27Z [Term] id: GO:0090166 name: Golgi disassembly namespace: biological_process def: "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus disassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005794 ! Golgi apparatus relationship: part_of GO:0048313 ! Golgi inheritance relationship: results_in_disassembly_of GO:0005794 ! Golgi apparatus created_by: tb creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090168 name: Golgi reassembly namespace: biological_process def: "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." [GOC:ascb_2009, GOC:dph, GOC:tb] synonym: "Golgi apparatus reassembly" EXACT [] is_a: GO:0007030 ! Golgi organization is_a: GO:0022607 ! cellular component assembly relationship: part_of GO:0048313 ! Golgi inheritance created_by: tb creation_date: 2009-12-08T09:15:11Z [Term] id: GO:0090170 name: regulation of Golgi inheritance namespace: biological_process def: "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048313 ! Golgi inheritance relationship: regulates GO:0048313 ! Golgi inheritance created_by: tb creation_date: 2009-12-11T10:21:59Z [Term] id: GO:0090171 name: chondrocyte morphogenesis namespace: biological_process def: "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0000904 ! cell morphogenesis involved in differentiation intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_maturation_of CL:0000138 ! chondrocyte relationship: part_of GO:0002063 ! chondrocyte development relationship: results_in_maturation_of CL:0000138 ! chondrocyte created_by: tb creation_date: 2009-12-11T10:36:02Z [Term] id: GO:0090174 name: organelle membrane fusion namespace: biological_process def: "The joining of two lipid bilayers to form a single organelle membrane." [GOC:ascb_2009, GOC:dph, GOC:tb] is_a: GO:0048284 ! organelle fusion is_a: GO:0061025 ! membrane fusion intersection_of: GO:0061025 ! membrane fusion intersection_of: results_in_fusion_of GO:0031090 ! organelle membrane relationship: results_in_fusion_of GO:0031090 ! organelle membrane created_by: tb creation_date: 2009-12-11T11:44:58Z [Term] id: GO:0090183 name: regulation of kidney development namespace: biological_process def: "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001822 ! kidney development relationship: regulates GO:0001822 ! kidney development created_by: tb creation_date: 2009-12-18T10:50:56Z [Term] id: GO:0090184 name: positive regulation of kidney development namespace: biological_process def: "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "positive regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001822 ! kidney development relationship: positively_regulates GO:0001822 ! kidney development created_by: tb creation_date: 2009-12-18T10:52:01Z [Term] id: GO:0090185 name: negative regulation of kidney development namespace: biological_process def: "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." [GOC:dph, GOC:tb, GOC:yaf] synonym: "negative regulation of nephrogenesis" RELATED [GOC:dph, GOC:tb] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090183 ! regulation of kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001822 ! kidney development relationship: negatively_regulates GO:0001822 ! kidney development created_by: tb creation_date: 2009-12-18T10:58:45Z [Term] id: GO:0090189 name: regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:0090183 ! regulation of kidney development is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis relationship: regulates GO:0001658 ! branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090190 name: positive regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis relationship: positively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090191 name: negative regulation of branching involved in ureteric bud morphogenesis namespace: biological_process def: "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." [GOC:dph, GOC:tb, GOC:yaf] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0090189 ! regulation of branching involved in ureteric bud morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis relationship: negatively_regulates GO:0001658 ! branching involved in ureteric bud morphogenesis created_by: tb creation_date: 2009-12-18T11:11:17Z [Term] id: GO:0090257 name: regulation of muscle system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." [GOC:dph, GOC:tb] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003012 ! muscle system process relationship: regulates GO:0003012 ! muscle system process created_by: tb creation_date: 2010-02-03T11:48:13Z [Term] id: GO:0090273 name: regulation of somatostatin secretion namespace: biological_process def: "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070253 ! somatostatin secretion relationship: regulates GO:0070253 ! somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090274 name: positive regulation of somatostatin secretion namespace: biological_process def: "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090277 ! positive regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070253 ! somatostatin secretion relationship: positively_regulates GO:0070253 ! somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090275 name: negative regulation of somatostatin secretion namespace: biological_process def: "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." [GOC:BHF] is_a: GO:0090273 ! regulation of somatostatin secretion is_a: GO:0090278 ! negative regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070253 ! somatostatin secretion relationship: negatively_regulates GO:0070253 ! somatostatin secretion created_by: tb creation_date: 2010-02-05T02:54:14Z [Term] id: GO:0090276 name: regulation of peptide hormone secretion namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002791 ! regulation of peptide secretion is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030072 ! peptide hormone secretion relationship: regulates GO:0030072 ! peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090277 name: positive regulation of peptide hormone secretion namespace: biological_process def: "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002793 ! positive regulation of peptide secretion is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030072 ! peptide hormone secretion relationship: positively_regulates GO:0030072 ! peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090278 name: negative regulation of peptide hormone secretion namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." [GOC:tb] is_a: GO:0002792 ! negative regulation of peptide secretion is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0090276 ! regulation of peptide hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030072 ! peptide hormone secretion relationship: negatively_regulates GO:0030072 ! peptide hormone secretion created_by: tb creation_date: 2010-02-05T02:56:39Z [Term] id: GO:0090299 name: regulation of neural crest formation namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." [GOC:tb] is_a: GO:0010717 ! regulation of epithelial to mesenchymal transition is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014029 ! neural crest formation relationship: regulates GO:0014029 ! neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090300 name: positive regulation of neural crest formation namespace: biological_process def: "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] is_a: GO:0010718 ! positive regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014029 ! neural crest formation relationship: positively_regulates GO:0014029 ! neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090301 name: negative regulation of neural crest formation namespace: biological_process def: "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." [GOC:tb] is_a: GO:0010719 ! negative regulation of epithelial to mesenchymal transition is_a: GO:0090299 ! regulation of neural crest formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014029 ! neural crest formation relationship: negatively_regulates GO:0014029 ! neural crest formation created_by: tb creation_date: 2010-03-12T04:08:26Z [Term] id: GO:0090304 name: nucleic acid metabolic process namespace: biological_process def: "Any cellular metabolic process involving nucleic acids." [GOC:dph, GOC:tb] is_a: GO:0006139 ! nucleobase-containing compound metabolic process is_a: GO:0043170 ! macromolecule metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33696 ! nucleic acid relationship: has_primary_input_or_output CHEBI:33696 ! nucleic acid created_by: tb creation_date: 2010-04-07T10:18:47Z [Term] id: GO:0090316 name: positive regulation of intracellular protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051222 ! positive regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006886 ! intracellular protein transport relationship: positively_regulates GO:0006886 ! intracellular protein transport created_by: tb creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090317 name: negative regulation of intracellular protein transport namespace: biological_process def: "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." [GOC:tb] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0051224 ! negative regulation of protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006886 ! intracellular protein transport relationship: negatively_regulates GO:0006886 ! intracellular protein transport created_by: tb creation_date: 2010-04-16T03:45:07Z [Term] id: GO:0090325 name: regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050795 ! regulation of behavior intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031987 ! locomotion involved in locomotory behavior relationship: regulates GO:0031987 ! locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:24:29Z [Term] id: GO:0090326 name: positive regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048520 ! positive regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0050789 ! regulation of biological process intersection_of: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior relationship: positively_regulates GO:0031987 ! locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090327 name: negative regulation of locomotion involved in locomotory behavior namespace: biological_process def: "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." [GOC:dph, GOC:kmv, GOC:tb] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048521 ! negative regulation of behavior is_a: GO:0090325 ! regulation of locomotion involved in locomotory behavior intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior relationship: negatively_regulates GO:0031987 ! locomotion involved in locomotory behavior created_by: tb creation_date: 2010-05-14T10:26:58Z [Term] id: GO:0090425 name: acinar cell differentiation namespace: biological_process def: "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." [GOC:dph, GOC:tb] is_a: GO:0002067 ! glandular epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000622 ! acinar cell relationship: results_in_acquisition_of_features_of CL:0000622 ! acinar cell created_by: tb creation_date: 2012-05-04T09:24:48Z [Term] id: GO:0090435 name: protein localization to nuclear envelope namespace: biological_process def: "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." [GOC:tb] synonym: "protein localization in nuclear envelope" EXACT [] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005635 ! nuclear envelope relationship: has_target_end_location GO:0005635 ! nuclear envelope created_by: tb creation_date: 2012-07-30T01:50:41Z [Term] id: GO:0090493 name: catecholamine uptake namespace: biological_process def: "The directed movement of catecholamine into a cell." [GOC:dph, GOC:tb] is_a: GO:0051937 ! catecholamine transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:33567 ! catecholamine intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure relationship: has_target_start_location GO:0005576 ! extracellular region created_by: tb creation_date: 2012-10-17T11:06:17Z [Term] id: GO:0090496 name: mesenchyme migration involved in limb bud formation namespace: biological_process def: "The migration of mesenchymal tissue that contributes to the formation of a limb bud." [GOC:dph, GOC:tb] is_a: GO:0090131 ! mesenchyme migration intersection_of: GO:0090131 ! mesenchyme migration intersection_of: part_of GO:0060174 ! limb bud formation relationship: part_of GO:0060174 ! limb bud formation created_by: tb creation_date: 2012-10-17T12:04:20Z [Term] id: GO:0090497 name: mesenchymal cell migration namespace: biological_process def: "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." [GOC:dph, GOC:tb] is_a: GO:0001667 ! ameboidal-type cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0008019 ! mesenchymal cell relationship: results_in_movement_of CL:0008019 ! mesenchymal cell created_by: tb creation_date: 2012-10-17T12:08:17Z [Term] id: GO:0090596 name: sensory organ morphogenesis namespace: biological_process def: "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." [GOC:kmv, ISBN:978-0199210893] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0000020 ! sense organ relationship: part_of GO:0007423 ! sensory organ development relationship: results_in_morphogenesis_of UBERON:0000020 ! sense organ created_by: tb creation_date: 2014-08-22T13:23:20Z [Term] id: GO:0090598 name: male anatomical structure morphogenesis namespace: biological_process def: "The processes by which anatomical structures that are only present in the male organism are generated and organized." [GOC:kmv, GOC:tb] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0014403 ! male anatomical structure relationship: part_of GO:0046661 ! male sex differentiation relationship: results_in_morphogenesis_of UBERON:0014403 ! male anatomical structure created_by: tb creation_date: 2014-08-22T13:29:45Z [Term] id: GO:0090685 name: RNA localization to nucleus namespace: biological_process def: "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." [GOC:mah, PMID:26305931] synonym: "RNA localisation to nucleus" EXACT [GOC:mah] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: has_target_end_location GO:0005634 ! nucleus relationship: has_target_end_location GO:0005634 ! nucleus created_by: tb creation_date: 2016-07-19T17:00:49Z [Term] id: GO:0090741 name: pigment granule membrane namespace: cellular_component def: "Any membrane that is part of a pigment granule." [PMID:11294610] is_a: GO:0030659 ! cytoplasmic vesicle membrane is_a: GO:0098588 ! bounding membrane of organelle intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0048770 ! pigment granule relationship: bounding_layer_of GO:0048770 ! pigment granule relationship: part_of GO:0048770 ! pigment granule created_by: tb creation_date: 2017-05-16T22:33:39Z [Term] id: GO:0097014 name: ciliary plasm namespace: cellular_component def: "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." [GOC:BHF, GOC:cilia, GOC:dos, PMID:17895364] comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm". synonym: "cilial cytoplasm" RELATED [] synonym: "ciliary cytoplasm" RELATED [] synonym: "cilium cytoplasm" RELATED [] synonym: "cilium plasm" EXACT [] synonym: "microtubule-based flagellar cytoplasm" RELATED [] synonym: "microtubule-based flagellar matrix" NARROW [] synonym: "microtubule-based flagellum cytoplasm" RELATED [] synonym: "microtubule-based flagellum matrix" NARROW [] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0005929 ! cilium relationship: part_of GO:0005929 ! cilium created_by: pr creation_date: 2011-03-23T01:52:31Z [Term] id: GO:0097026 name: dendritic cell dendrite assembly namespace: biological_process def: "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, PMID:12200351] comment: Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals. synonym: "dendritic extension" BROAD [] is_a: GO:0120031 ! plasma membrane bounded cell projection assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0097511 ! dendritic cell dendrite relationship: results_in_assembly_of GO:0097511 ! dendritic cell dendrite created_by: pr creation_date: 2011-03-31T04:52:53Z [Term] id: GO:0097028 name: dendritic cell differentiation namespace: biological_process def: "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:pr] comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'. is_a: GO:1903131 ! mononuclear cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000451 ! dendritic cell relationship: results_in_acquisition_of_features_of CL:0000451 ! dendritic cell created_by: pr creation_date: 2011-04-01T10:08:42Z [Term] id: GO:0097048 name: dendritic cell apoptotic process namespace: biological_process def: "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." [CL:0000451, GOC:BHF, GOC:mtg_apoptosis, PMID:15059845] synonym: "dendritic cell apoptosis" NARROW [] is_a: GO:0071887 ! leukocyte apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000451 ! dendritic cell relationship: occurs_in CL:0000451 ! dendritic cell created_by: pr creation_date: 2011-05-04T02:18:59Z [Term] id: GO:0097049 name: motor neuron apoptotic process namespace: biological_process def: "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:BHF, GOC:mtg_apoptosis, PMID:14523086] synonym: "motoneuron apoptosis" EXACT [] synonym: "motor neuron apoptosis" NARROW [] is_a: GO:0051402 ! neuron apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000100 ! motor neuron relationship: occurs_in CL:0000100 ! motor neuron created_by: pr creation_date: 2011-05-04T02:21:43Z [Term] id: GO:0097050 name: type B pancreatic cell apoptotic process namespace: biological_process def: "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin." [CL:0000169, GOC:BHF, GOC:mtg_apoptosis, PMID:16087305] synonym: "pancreatic B cell apoptosis" EXACT [] synonym: "pancreatic beta cell apoptosis" EXACT [] synonym: "type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000169 ! type B pancreatic cell relationship: occurs_in CL:0000169 ! type B pancreatic cell created_by: pr creation_date: 2011-05-04T02:24:38Z [Term] id: GO:0097060 name: synaptic membrane namespace: cellular_component def: "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." [GOC:BHF, PMID:20410104] subset: goslim_synapse is_a: GO:0098590 ! plasma membrane region intersection_of: GO:0098590 ! plasma membrane region intersection_of: part_of GO:0045202 ! synapse relationship: part_of GO:0045202 ! synapse created_by: pr creation_date: 2011-06-07T11:22:09Z [Term] id: GO:0097084 name: vascular associated smooth muscle cell development namespace: biological_process def: "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [GOC:BHF] synonym: "vascular smooth muscle cell development" EXACT [] is_a: GO:0055001 ! muscle cell development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of CL:0000359 ! vascular associated smooth muscle cell relationship: part_of GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: results_in_development_of CL:0000359 ! vascular associated smooth muscle cell created_by: pr creation_date: 2011-06-20T04:03:08Z [Term] id: GO:0097094 name: craniofacial suture morphogenesis namespace: biological_process def: "The process in which any suture between cranial and/or facial bones is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0009198 ! craniofacial suture relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0060349 ! bone morphogenesis relationship: part_of GO:1904888 ! cranial skeletal system development relationship: results_in_morphogenesis_of UBERON:0009198 ! craniofacial suture created_by: pr creation_date: 2011-07-05T02:51:54Z [Term] id: GO:0097095 name: frontonasal suture morphogenesis namespace: biological_process def: "The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized." [GOC:pr, GOC:sl, PMID:12416537, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] synonym: "nasofrontal suture morphogenesis" EXACT [] is_a: GO:0097094 ! craniofacial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0005404 ! frontonasal suture relationship: results_in_morphogenesis_of UBERON:0005404 ! frontonasal suture created_by: pr creation_date: 2011-07-05T02:57:46Z [Term] id: GO:0097096 name: facial suture morphogenesis namespace: biological_process def: "The process in which any suture between facial bones is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] is_a: GO:0097094 ! craniofacial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0009199 ! facial suture relationship: results_in_morphogenesis_of UBERON:0009199 ! facial suture created_by: pr creation_date: 2011-07-05T03:06:27Z [Term] id: GO:0097097 name: nasal suture morphogenesis namespace: biological_process def: "The process in which the nasal suture is generated and organized." [GOC:pr, GOC:sl, Wikipedia:Cranial_sutures, Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system] synonym: "internasal suture morphogenesis" EXACT [] is_a: GO:0097096 ! facial suture morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0009203 ! internasal suture relationship: results_in_morphogenesis_of UBERON:0009203 ! internasal suture created_by: pr creation_date: 2011-07-05T03:09:04Z [Term] id: GO:0097152 name: mesenchymal cell apoptotic process namespace: biological_process def: "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." [CL:0000134, GOC:mtg_apoptosis, GOC:yaf, PMID:18231833] synonym: "mesenchymal cell apoptosis" NARROW [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0008019 ! mesenchymal cell relationship: occurs_in CL:0008019 ! mesenchymal cell created_by: pr creation_date: 2011-09-06T02:31:59Z [Term] id: GO:0097164 name: ammonium ion metabolic process namespace: biological_process def: "The chemical reactions and pathways involving the ammonium ion." [GOC:dhl, GOC:tb, PMID:14671018] synonym: "ammonium ion metabolism" EXACT [] synonym: "ammonium metabolic process" RELATED [] is_a: GO:0006807 ! nitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:28938 ! ammonium relationship: has_primary_input_or_output CHEBI:28938 ! ammonium created_by: pr creation_date: 2011-09-28T04:21:30Z [Term] id: GO:0097186 name: amelogenesis namespace: biological_process def: "The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage." [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346] synonym: "enamel development" EXACT [] is_a: GO:0042475 ! odontogenesis of dentin-containing tooth is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001752 ! enamel relationship: results_in_formation_of UBERON:0001752 ! enamel created_by: pr creation_date: 2011-11-21T09:01:24Z [Term] id: GO:0097187 name: dentinogenesis namespace: biological_process def: "The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin." [GOC:cjm, GOC:sl, PMID:10206335, PMID:21196346] synonym: "dentin development" EXACT [] synonym: "dentine development" EXACT [] is_a: GO:0042475 ! odontogenesis of dentin-containing tooth is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0001751 ! dentine relationship: results_in_formation_of UBERON:0001751 ! dentine created_by: pr creation_date: 2011-11-21T09:04:17Z [Term] id: GO:0097190 name: apoptotic signaling pathway namespace: biological_process alt_id: GO:0008624 def: "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." [GOC:mtg_apoptosis] comment: This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways. synonym: "apoptotic signalling pathway" EXACT [GOC:mah] synonym: "induction of apoptosis by extracellular signals" EXACT [] is_a: GO:0007165 ! signal transduction relationship: part_of GO:0006915 ! apoptotic process created_by: pr creation_date: 2011-11-23T09:30:23Z [Term] id: GO:0097194 name: execution phase of apoptosis namespace: biological_process def: "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." [GOC:mtg_apoptosis, PMID:21760595] synonym: "apoptosis" NARROW [] synonym: "execution phase of apoptotic process" EXACT [] is_a: GO:0009987 ! cellular process relationship: has_part GO:0032060 ! bleb assembly relationship: part_of GO:0006915 ! apoptotic process created_by: pr creation_date: 2011-11-23T09:45:24Z [Term] id: GO:0097237 name: cellular response to toxic substance namespace: biological_process def: "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." [GOC:pr] created_by: pr creation_date: 2012-02-02T12:23:31Z [Term] id: GO:0097252 name: oligodendrocyte apoptotic process namespace: biological_process def: "Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons." [CL:0000128, GOC:mtg_apoptosis, GOC:yaf, PMID:16723520] synonym: "oligodendrocyte apoptosis" NARROW [] is_a: GO:0034349 ! glial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000128 ! oligodendrocyte relationship: occurs_in CL:0000128 ! oligodendrocyte created_by: pr creation_date: 2012-03-05T10:51:15Z [Term] id: GO:0097254 name: renal tubular secretion namespace: biological_process def: "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs." [GOC:rph, PMID:25287933, Wikipedia:Renal_secretion#Secretion] is_a: GO:0003014 ! renal system process is_a: GO:0007588 ! excretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI created_by: pr creation_date: 2012-03-05T02:03:58Z [Term] id: GO:0097284 name: hepatocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a hepatocyte, the main structural component of the liver." [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020] synonym: "hepatocyte apoptosis" NARROW [] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000182 ! hepatocyte relationship: occurs_in CL:0000182 ! hepatocyte created_by: pr creation_date: 2012-03-29T10:23:21Z [Term] id: GO:0097355 name: protein localization to heterochromatin namespace: biological_process def: "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." [GOC:mah] synonym: "protein localisation to heterochromatin" EXACT [GOC:mah] is_a: GO:0071168 ! protein localization to chromatin intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0000792 ! heterochromatin relationship: has_target_end_location GO:0000792 ! heterochromatin created_by: pr creation_date: 2012-07-03T03:19:07Z [Term] id: GO:0097360 name: chorionic trophoblast cell proliferation namespace: biological_process def: "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population." [CL:0011101, GOC:BHF, PMID:15150278] is_a: GO:0008283 ! cell population proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0011101 ! chorionic trophoblast cell relationship: acts_on_population_of CL:0011101 ! chorionic trophoblast cell created_by: pr creation_date: 2012-07-19T10:17:37Z [Term] id: GO:0097386 name: glial cell projection namespace: cellular_component def: "A prolongation or process extending from a glial cell." [GOC:mc] synonym: "glial process" RELATED [] synonym: "glial projection" RELATED [] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000125 ! glial cell relationship: part_of CL:0000125 ! glial cell created_by: pr creation_date: 2012-10-22T13:55:54Z [Term] id: GO:0097402 name: neuroblast migration namespace: biological_process def: "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." [CL:0000031, GOC:jc, PMID:15543145] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000031 ! neuroblast (sensu Vertebrata) relationship: results_in_movement_of CL:0000031 ! neuroblast (sensu Vertebrata) created_by: pr creation_date: 2012-10-29T08:24:37Z [Term] id: GO:0097427 name: microtubule bundle namespace: cellular_component def: "An arrangement of closely apposed microtubules running parallel to each other." [NIF_Subcellular:sao1872343973] synonym: "microtubule fascicle" EXACT [] xref: NIF_Subcellular:sao1872343973 is_a: GO:0110165 ! cellular anatomical entity relationship: has_part GO:0005874 ! microtubule relationship: part_of GO:0005856 ! cytoskeleton created_by: pr creation_date: 2012-11-07T15:01:27Z [Term] id: GO:0097435 name: supramolecular fiber organization namespace: biological_process alt_id: GO:0043206 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:pr] synonym: "extracellular fibril organisation" NARROW [] synonym: "extracellular fibril organization" NARROW [] synonym: "extracellular fibril organization and biogenesis" NARROW [GOC:mah] synonym: "fibril organisation" RELATED [] synonym: "fibril organization" RELATED [] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0099512 ! supramolecular fiber relationship: results_in_organization_of GO:0099512 ! supramolecular fiber created_by: pr creation_date: 2012-11-27T15:46:25Z [Term] id: GO:0097454 name: Schwann cell microvillus namespace: cellular_component def: "Small finger-like extension of a Schwann cell that contacts the nodal membrane." [NIF_Subcellular:sao1890444066, PMID:15988042] xref: NIF_Subcellular:sao1890444066 is_a: GO:0005902 ! microvillus is_a: GO:0097386 ! glial cell projection intersection_of: GO:0005902 ! microvillus intersection_of: part_of CL:0002573 ! Schwann cell relationship: part_of CL:0002573 ! Schwann cell created_by: pr creation_date: 2012-12-19T13:01:02Z [Term] id: GO:0097473 name: retinal rod cell apoptotic process namespace: biological_process def: "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000604, GOC:jc, PMID:17202487] synonym: "rod photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000604 ! retinal rod cell relationship: occurs_in CL:0000604 ! retinal rod cell created_by: pr creation_date: 2013-03-21T09:44:45Z [Term] id: GO:0097474 name: retinal cone cell apoptotic process namespace: biological_process def: "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." [CL:0000573, GOC:jc] synonym: "cone photoreceptor apoptotic process" EXACT [] is_a: GO:0051402 ! neuron apoptotic process is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000573 ! retinal cone cell relationship: occurs_in CL:0000573 ! retinal cone cell created_by: pr creation_date: 2013-03-21T09:46:22Z [Term] id: GO:0097475 name: motor neuron migration namespace: biological_process def: "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." [CL:0000100, GOC:yaf, PMID:20711475] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000100 ! motor neuron relationship: results_in_movement_of CL:0000100 ! motor neuron created_by: pr creation_date: 2013-04-23T13:00:46Z [Term] id: GO:0097476 name: spinal cord motor neuron migration namespace: biological_process def: "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." [CL:0011001, GOC:yaf, PMID:20711475] is_a: GO:0097475 ! motor neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0011001 ! spinal cord motor neuron relationship: results_in_movement_of CL:0011001 ! spinal cord motor neuron created_by: pr creation_date: 2013-04-23T13:03:46Z [Term] id: GO:0097511 name: dendritic cell dendrite namespace: cellular_component def: "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." [CL:0000451, GOC:BHF, GOC:cjm, PMID:12200351] is_a: GO:0120025 ! plasma membrane bounded cell projection intersection_of: GO:0120025 ! plasma membrane bounded cell projection intersection_of: part_of CL:0000451 ! dendritic cell relationship: part_of CL:0000451 ! dendritic cell created_by: pr creation_date: 2013-10-16T13:02:25Z [Term] id: GO:0097512 name: cardiac myofibril namespace: cellular_component def: "A cardiac myofibril is a myofibril specific to cardiac muscle cells." [GOC:cjm, GOC:devbiol] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: part_of CL:0000746 ! cardiac muscle cell relationship: part_of CL:0000746 ! cardiac muscle cell created_by: pr creation_date: 2013-10-16T13:04:58Z [Term] id: GO:0097524 name: sperm plasma membrane namespace: cellular_component def: "A plasma membrane that is part of a sperm cell." [GOC:cjm] is_a: GO:0005886 ! plasma membrane intersection_of: GO:0005886 ! plasma membrane intersection_of: part_of CL:0000019 ! sperm relationship: part_of CL:0000019 ! sperm created_by: pr creation_date: 2013-10-18T11:31:17Z [Term] id: GO:0097529 name: myeloid leukocyte migration namespace: biological_process def: "The movement of a myeloid leukocyte within or between different tissues and organs of the body." [GOC:cvs, PMID:22342843, PMID:24157461] is_a: GO:0050900 ! leukocyte migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000766 ! myeloid leukocyte relationship: results_in_movement_of CL:0000766 ! myeloid leukocyte created_by: pr creation_date: 2013-11-11T13:59:43Z [Term] id: GO:0097534 name: lymphoid lineage cell migration namespace: biological_process def: "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." [GOC:pr, PMID:22342843] synonym: "lymphoid lineage restricted progenitor cell migration" EXACT [] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000838 ! lymphoid lineage restricted progenitor cell relationship: results_in_movement_of CL:0000838 ! lymphoid lineage restricted progenitor cell created_by: pr creation_date: 2013-11-28T10:47:15Z [Term] id: GO:0097576 name: vacuole fusion namespace: biological_process def: "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." [GOC:pr, GOC:vw, Wikipedia:Vacuole] is_a: GO:0007033 ! vacuole organization is_a: GO:0048284 ! organelle fusion intersection_of: GO:0009987 ! cellular process intersection_of: results_in_fusion_of GO:0005773 ! vacuole relationship: results_in_fusion_of GO:0005773 ! vacuole created_by: pr creation_date: 2014-02-28T09:49:31Z [Term] id: GO:0097708 name: intracellular vesicle namespace: cellular_component def: "Any vesicle that is part of the intracellular region." [GOC:vesicles] is_a: GO:0031982 ! vesicle is_a: GO:0043231 ! intracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005622 ! intracellular anatomical structure created_by: pr creation_date: 2016-03-29T17:39:45Z [Term] id: GO:0097711 name: ciliary basal body-plasma membrane docking namespace: biological_process def: "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane." [GOC:cilia, PMID:13978319, PMID:23348840, PMID:23530209, PMID:25686250, PMID:26981235, Reactome:R-HSA-5620912.1] comment: Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella. synonym: "anchoring of the basal body to the plasma membrane" RELATED [] synonym: "ciliary basal body docking" EXACT [] xref: Reactome:R-HSA-5620912.1 is_a: GO:0140056 ! organelle localization by membrane tethering relationship: part_of GO:0060271 ! cilium assembly created_by: pr creation_date: 2016-08-05T16:12:33Z [Term] id: GO:0097712 name: vesicle targeting, trans-Golgi to periciliary membrane compartment namespace: biological_process def: "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces." [GOC:cilia, PMID:20106869, PMID:23351793, PMID:24814148, PMID:26485645, Reactome:R-HSA-5620920.1] is_a: GO:0048199 ! vesicle targeting, to, from or within Golgi relationship: part_of GO:0060271 ! cilium assembly created_by: pr creation_date: 2016-08-05T16:16:28Z [Term] id: GO:0097722 name: sperm motility namespace: biological_process def: "Any process involved in the controlled movement of a sperm cell." [GOC:cilia, GOC:krc] subset: gocheck_do_not_annotate synonym: "sperm movement" EXACT [] is_a: GO:0022414 ! reproductive process is_a: GO:0048870 ! cell motility intersection_of: GO:0048870 ! cell motility intersection_of: results_in_movement_of CL:0000019 ! sperm relationship: results_in_movement_of CL:0000019 ! sperm created_by: pr creation_date: 2016-09-01T12:00:45Z [Term] id: GO:0097734 name: extracellular exosome biogenesis namespace: biological_process def: "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:bf, GOC:PARL, PMID:19442504, PMID:25392495] synonym: "exosome assembly or secretion" EXACT [] synonym: "exosome biogenesis" EXACT [] synonym: "exosome production" EXACT [] synonym: "ILV assembly" RELATED [] synonym: "intraluminal vesicle assembly" RELATED [] is_a: GO:0140112 ! extracellular vesicle biogenesis created_by: pr creation_date: 2016-10-03T14:35:25Z [Term] id: GO:0098523 name: neuromuscular junction of myotube namespace: cellular_component def: "A neuromuscular junction in which the target muscle cell is a myotube." [GOC:dos] comment: In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes. is_a: GO:0031594 ! neuromuscular junction intersection_of: GO:0045202 ! synapse intersection_of: overlaps CL:0000100 ! motor neuron intersection_of: overlaps CL:0002372 ! myotube relationship: overlaps CL:0002372 ! myotube created_by: dos creation_date: 2013-10-14T12:05:12Z [Term] id: GO:0098528 name: skeletal muscle fiber differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." [GOC:dos] is_a: GO:0014902 ! myotube differentiation is_a: GO:0035914 ! skeletal muscle cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0008002 ! skeletal muscle fiber relationship: results_in_acquisition_of_features_of CL:0008002 ! skeletal muscle fiber created_by: dos creation_date: 2013-10-15T14:00:34Z [Term] id: GO:0098542 name: defense response to other organism namespace: biological_process alt_id: GO:0009814 def: "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." [GOC:dos] subset: goslim_generic subset: prokaryote_subset synonym: "defence response incompatible interaction" NARROW [] synonym: "defence response to pathogen, incompatible interaction" NARROW [] synonym: "defense response, incompatible interaction" NARROW [] synonym: "resistance response to pathogen" NARROW [] is_a: GO:0006952 ! defense response is_a: GO:0051707 ! response to other organism intersection_of: GO:0006952 ! defense response intersection_of: has_input NCBITaxon_Union:0000030 property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22173" xsd:anyURI created_by: dos creation_date: 2013-11-11T12:59:11Z [Term] id: GO:0098588 name: bounding membrane of organelle namespace: cellular_component def: "The lipid bilayer that forms the outer-most layer of an organelle." [GOC:dos] comment: Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes. is_a: GO:0031090 ! organelle membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0043226 ! organelle relationship: bounding_layer_of GO:0043226 ! organelle created_by: dos creation_date: 2014-02-26T13:41:31Z [Term] id: GO:0098590 name: plasma membrane region namespace: cellular_component def: "A membrane that is a (regional) part of the plasma membrane." [GOC:dos] comment: Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. subset: gocheck_do_not_manually_annotate synonym: "region of plasma membrane" EXACT [] is_a: GO:0016020 ! membrane intersection_of: GO:0016020 ! membrane intersection_of: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0005886 ! plasma membrane created_by: dos creation_date: 2014-03-06T11:55:32Z [Term] id: GO:0098609 name: cell-cell adhesion namespace: biological_process alt_id: GO:0016337 def: "The attachment of one cell to another cell via adhesion molecules." [GOC:dos] synonym: "single organismal cell-cell adhesion" RELATED [] is_a: GO:0007155 ! cell adhesion created_by: dos creation_date: 2014-04-16T13:40:03Z [Term] id: GO:0098635 name: protein complex involved in cell-cell adhesion namespace: cellular_component def: "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." [GOC:dos] is_a: GO:0098636 ! protein complex involved in cell adhesion intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of_part_of GO:0098609 ! cell-cell adhesion relationship: capable_of_part_of GO:0098609 ! cell-cell adhesion [Term] id: GO:0098636 name: protein complex involved in cell adhesion namespace: cellular_component alt_id: GO:1990307 def: "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." [GOC:dos] synonym: "cell adhesion complex" RELATED [] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of_part_of GO:0007155 ! cell adhesion relationship: capable_of_part_of GO:0007155 ! cell adhesion [Term] id: GO:0098642 name: network-forming collagen trimer namespace: cellular_component def: "A collagen trimer that forms networks." [PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0098645 ! collagen network relationship: part_of GO:0098645 ! collagen network [Term] id: GO:0098643 name: banded collagen fibril namespace: cellular_component def: "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." [GOC:dos, PMID:21421911] is_a: GO:0098644 ! complex of collagen trimers is_a: GO:0099512 ! supramolecular fiber [Term] id: GO:0098644 name: complex of collagen trimers namespace: cellular_component def: "A complex of collagen trimers such as a fibril or collagen network." [GOC:dos] synonym: "Supramolecular aggregate of collagen" EXACT [PMID:19693541] synonym: "Supramolecular collagen assembly" EXACT [PMID:21421911] is_a: GO:0099080 ! supramolecular complex is_a: PR:000050567 ! protein-containing material entity relationship: has_part GO:0005581 ! collagen trimer relationship: part_of GO:0062023 ! collagen-containing extracellular matrix [Term] id: GO:0098645 name: collagen network namespace: cellular_component def: "A supramolecular complex that consists of collagen triple helices associated to form a network." [GOC:dos, PMID:21421911] is_a: GO:0098644 ! complex of collagen trimers is_a: GO:0099081 ! supramolecular polymer [Term] id: GO:0098651 name: basement membrane collagen trimer namespace: cellular_component def: "Any collagen timer that is part of a basement membrane." [GOC:dos, PMID:21421911] is_a: GO:0005581 ! collagen trimer intersection_of: GO:0005581 ! collagen trimer intersection_of: part_of GO:0005604 ! basement membrane relationship: part_of GO:0005604 ! basement membrane [Term] id: GO:0098655 name: monoatomic cation transmembrane transport namespace: biological_process alt_id: GO:0099132 def: "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." [GOC:dos, GOC:vw] synonym: "ATP hydrolysis coupled cation transmembrane transport" NARROW [] synonym: "cation transmembrane transport" BROAD [] is_a: GO:0006812 ! monoatomic cation transport is_a: GO:0034220 ! monoatomic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:23906 ! monoatomic cation intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0098657 name: import into cell namespace: biological_process def: "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:dos] synonym: "uptake" BROAD [] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24431 ! chemical entity intersection_of: has_target_end_location GO:0005737 ! cytoplasm intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_primary_input CHEBI:24431 ! chemical entity relationship: has_target_end_location GO:0005737 ! cytoplasm relationship: has_target_start_location GO:0005576 ! extracellular region [Term] id: GO:0098660 name: inorganic ion transmembrane transport namespace: biological_process def: "The process in which an inorganic ion is transported across a membrane." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "inorganic ion membrane transport" EXACT [] synonym: "transmembrane inorganic ion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:36914 ! inorganic ion intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:36914 ! inorganic ion [Term] id: GO:0098661 name: inorganic anion transmembrane transport namespace: biological_process def: "The process in which an inorganic anion is transported across a membrane." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "inorganic anion membrane transport" EXACT [] synonym: "transmembrane inorganic anion transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0015698 ! inorganic anion transport is_a: GO:0098660 ! inorganic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:24834 ! inorganic anion intersection_of: results_in_transport_across GO:0016020 ! membrane [Term] id: GO:0098662 name: inorganic cation transmembrane transport namespace: biological_process alt_id: GO:0015672 alt_id: GO:0072511 def: "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." [GOC:mah] comment: Note that this term is not intended for use in annotating lateral movement within membranes. synonym: "divalent inorganic cation transport" NARROW [] synonym: "inorganic cation membrane transport" EXACT [] synonym: "monovalent inorganic cation transport" NARROW [] synonym: "transmembrane inorganic cation transport" EXACT [GOC:dph, GOC:tb] is_a: GO:0098660 ! inorganic ion transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:36915 ! inorganic cation intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:36915 ! inorganic cation [Term] id: GO:0098722 name: asymmetric stem cell division namespace: biological_process def: "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." [GOC:dos, PMID:18513950] is_a: GO:0008356 ! asymmetric cell division is_a: GO:0017145 ! stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_input CL:0000034 ! stem cell [Term] id: GO:0098723 name: skeletal muscle myofibril namespace: cellular_component def: "A myofibril of a skeletal muscle fiber." [GOC:dos] is_a: GO:0030016 ! myofibril intersection_of: GO:0030016 ! myofibril intersection_of: part_of CL:0008002 ! skeletal muscle fiber relationship: part_of CL:0008002 ! skeletal muscle fiber [Term] id: GO:0098727 name: maintenance of cell number namespace: biological_process def: "Any process by which the numbers of cells of a particular type or in a tissue are maintained." [GOC:dos] is_a: GO:0032502 ! developmental process [Term] id: GO:0098728 name: germline stem cell asymmetric division namespace: biological_process def: "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." [GOC:dos] is_a: GO:0042078 ! germ-line stem cell division is_a: GO:0098722 ! asymmetric stem cell division intersection_of: GO:0008356 ! asymmetric cell division intersection_of: has_input CL:0000014 ! germ line stem cell [Term] id: GO:0098751 name: bone cell development namespace: biological_process def: "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." [GOC:dos] comment: Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development. subset: gocheck_do_not_annotate is_a: GO:0048468 ! cell development intersection_of: GO:0032502 ! developmental process intersection_of: results_in_development_of CL:0001035 ! bone cell relationship: part_of GO:0060348 ! bone development relationship: results_in_development_of CL:0001035 ! bone cell [Term] id: GO:0098754 name: detoxification namespace: biological_process def: "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:dos] subset: goslim_generic subset: goslim_pombe subset: prokaryote_subset is_a: GO:0008150 ! biological_process relationship: part_of GO:0009636 ! response to toxic substance [Term] id: GO:0098773 name: skin epidermis development namespace: biological_process def: "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." [GOC:dos] is_a: GO:0008544 ! epidermis development is_a: GO:0060429 ! epithelium development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001003 ! skin epidermis relationship: part_of GO:0043588 ! skin development relationship: results_in_development_of UBERON:0001003 ! skin epidermis [Term] id: GO:0098793 name: presynapse namespace: cellular_component def: "The part of a synapse that is part of the presynaptic cell." [GOC:dos] subset: goslim_synapse synonym: "presynaptic terminal" EXACT [] is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000540 ! neuron relationship: part_of GO:0045202 ! synapse [Term] id: GO:0098794 name: postsynapse namespace: cellular_component def: "The part of a synapse that is part of the post-synaptic cell." [GOC:dos] subset: goslim_synapse is_a: GO:0110165 ! cellular anatomical entity relationship: part_of CL:0000000 ! cell relationship: part_of GO:0045202 ! synapse [Term] id: GO:0098796 name: membrane protein complex namespace: cellular_component def: "Any protein complex that is part of a membrane." [GOC:dos] subset: goslim_metagenomics is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0016020 ! membrane relationship: part_of GO:0016020 ! membrane [Term] id: GO:0098797 name: plasma membrane protein complex namespace: cellular_component def: "Any protein complex that is part of the plasma membrane." [GOC:dos] is_a: GO:0098796 ! membrane protein complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0005886 ! plasma membrane relationship: part_of GO:0005886 ! plasma membrane [Term] id: GO:0098801 name: regulation of renal system process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system." [GOC:dos] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003014 ! renal system process relationship: regulates GO:0003014 ! renal system process [Term] id: GO:0098813 name: nuclear chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:dos] is_a: GO:0007059 ! chromosome segregation [Term] id: GO:0098840 name: protein transport along microtubule namespace: biological_process def: "The directed movement of a protein along a microtubule, mediated by motor proteins." [PMID:25987607] synonym: "microtubule-based protein transport" BROAD [] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0010970 ! transport along microtubule is_a: GO:0099118 ! microtubule-based protein transport intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0098858 name: actin-based cell projection namespace: cellular_component def: "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." [PMID:15661519] is_a: GO:0120025 ! plasma membrane bounded cell projection relationship: has_part GO:0005884 ! actin filament [Term] id: GO:0098867 name: intramembranous bone growth namespace: biological_process def: "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." [PMID:26399686] is_a: GO:0098868 ! bone growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0002514 ! intramembranous bone relationship: results_in_growth_of UBERON:0002514 ! intramembranous bone [Term] id: GO:0098868 name: bone growth namespace: biological_process def: "The increase in size or mass of a bone that contributes to the shaping of that bone." [GOC:dos] is_a: GO:0035265 ! organ growth intersection_of: GO:0048589 ! developmental growth intersection_of: results_in_growth_of UBERON:0001474 ! bone element relationship: part_of GO:0060348 ! bone development relationship: results_in_growth_of UBERON:0001474 ! bone element [Term] id: GO:0098871 name: postsynaptic actin cytoskeleton namespace: cellular_component def: "The actin cytoskeleton that is part of a postsynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099571 ! postsynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse [Term] id: GO:0098876 name: vesicle-mediated transport to the plasma membrane namespace: biological_process def: "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." [GOC:dos] is_a: GO:0016192 ! vesicle-mediated transport is_a: GO:0051668 ! localization within membrane intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0005886 ! plasma membrane intersection_of: process_has_causal_agent GO:0031982 ! vesicle relationship: ends_with GO:0006887 ! exocytosis relationship: has_target_end_location GO:0005886 ! plasma membrane [Term] id: GO:0098883 name: synapse pruning namespace: biological_process def: "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." [GOC:dos, PMID:12062020, PMID:18083105, PMID:22632716, PMID:29844190] subset: goslim_synapse synonym: "synapse clearance" EXACT [GOC:aruk, GOC:bc, PMID:22632716] synonym: "synapse disassembly" EXACT syngo_official_label [PMID:12062020] synonym: "synapse elimination" EXACT [GOC:aruk, GOC:bc, PMID:18083105, PMID:29844190] synonym: "synapse removal" EXACT [GOC:aruk, GOC:bc, PMID:22632716] is_a: GO:0050808 ! synapse organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0045202 ! synapse relationship: results_in_disassembly_of GO:0045202 ! synapse [Term] id: GO:0098900 name: regulation of action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:dph, GOC:go_curators, GOC:tb, ISBN:978-0-07-139011-8] comment: The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term. is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0001508 ! action potential relationship: regulates GO:0001508 ! action potential [Term] id: GO:0098901 name: regulation of cardiac muscle cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dos, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086001 ! cardiac muscle cell action potential relationship: regulates GO:0086001 ! cardiac muscle cell action potential [Term] id: GO:0098904 name: regulation of AV node cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of atrioventricular node cardiac muscle cell action potential" EXACT [] synonym: "regulation of AV node cardiac muscle cell action potential" EXACT [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086016 ! AV node cell action potential relationship: regulates GO:0086016 ! AV node cell action potential created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098906 name: regulation of Purkinje myocyte action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086017 ! Purkinje myocyte action potential relationship: regulates GO:0086017 ! Purkinje myocyte action potential created_by: tb creation_date: 2011-11-10T08:58:56Z [Term] id: GO:0098907 name: regulation of SA node cell action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11] synonym: "regulation of SA node cardiac muscle cell action potential" EXACT [] synonym: "regulation of SAN cardiac muscle cell action potential" EXACT [] synonym: "regulation of sinoatrial node cardiac muscle cell action potential" EXACT [] synonym: "regulation of sinus node cardiac muscle cell action potential" NARROW [] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0098901 ! regulation of cardiac muscle cell action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0086015 ! SA node cell action potential relationship: regulates GO:0086015 ! SA node cell action potential created_by: tb creation_date: 2011-11-10T08:50:15Z [Term] id: GO:0098908 name: regulation of neuronal action potential namespace: biological_process def: "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." [GOC:dph, GOC:isa_complete, GOC:tb] synonym: "generation of action potential" RELATED [GOC:dph, GOC:tb] is_a: GO:0051969 ! regulation of transmission of nerve impulse is_a: GO:0098900 ! regulation of action potential intersection_of: GO:0050789 ! regulation of biological process intersection_of: regulates GO:0019228 ! neuronal action potential relationship: regulates GO:0019228 ! neuronal action potential [Term] id: GO:0098916 name: anterograde trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098794 ! postsynapse intersection_of: has_start_location GO:0098793 ! presynapse relationship: has_end_location GO:0098794 ! postsynapse relationship: has_start_location GO:0098793 ! presynapse [Term] id: GO:0098917 name: retrograde trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." [GOC:dos] is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse relationship: has_end_location GO:0098793 ! presynapse relationship: has_start_location GO:0098794 ! postsynapse [Term] id: GO:0098920 name: retrograde trans-synaptic signaling by lipid namespace: biological_process def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." [GOC:dos] subset: goslim_synapse is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099541 ! trans-synaptic signaling by lipid intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse intersection_of: process_has_causal_agent CHEBI:18059 ! lipid [Term] id: GO:0098926 name: postsynaptic signal transduction namespace: biological_process def: "Signal transduction in which the initial step occurs in a postsynapse." [GOC:dos] subset: goslim_synapse synonym: "postsynaptic signaling pathway" EXACT syngo_official_label [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: has_start_location GO:0098794 ! postsynapse relationship: has_start_location GO:0098794 ! postsynapse relationship: part_of GO:0099536 ! synaptic signaling [Term] id: GO:0098928 name: presynaptic signal transduction namespace: biological_process def: "Signal transduction in which the initial step occurs in a presynapse." [GOC:dos] subset: goslim_synapse synonym: "presynaptic signaling pathway" EXACT syngo_official_label [] is_a: GO:0007165 ! signal transduction intersection_of: GO:0007165 ! signal transduction intersection_of: has_start_location GO:0098793 ! presynapse relationship: has_start_location GO:0098793 ! presynapse [Term] id: GO:0098930 name: axonal transport namespace: biological_process def: "The directed movement of organelles or molecules along microtubules in axons." [ISBN:0815316194] subset: goslim_synapse synonym: "axon cargo transport" EXACT [] synonym: "axoplasmic transport" EXACT [] xref: Wikipedia:Axoplasmic_transport is_a: GO:0008088 ! axo-dendritic transport intersection_of: GO:0046907 ! intracellular transport intersection_of: occurs_in GO:0030424 ! axon intersection_of: results_in_transport_along GO:0005874 ! microtubule relationship: occurs_in GO:0030424 ! axon [Term] id: GO:0098974 name: postsynaptic actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099188 ! postsynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0098871 ! postsynaptic actin cytoskeleton relationship: results_in_organization_of GO:0098871 ! postsynaptic actin cytoskeleton [Term] id: GO:0098975 name: postsynapse of neuromuscular junction namespace: cellular_component def: "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." [GOC:dos, Wikipedia:Neuromuscular_junction&oldid=723623502] is_a: GO:0098794 ! postsynapse intersection_of: GO:0098794 ! postsynapse intersection_of: part_of CL:0000187 ! muscle cell intersection_of: part_of GO:0031594 ! neuromuscular junction relationship: part_of CL:0000187 ! muscle cell relationship: part_of GO:0031594 ! neuromuscular junction [Term] id: GO:0098981 name: cholinergic synapse namespace: cellular_component def: "A synapse that uses acetylcholine as a neurotransmitter." [GOC:dos] subset: goslim_synapse is_a: GO:0045202 ! synapse intersection_of: GO:0045202 ! synapse intersection_of: capable_of GO:0007271 ! synaptic transmission, cholinergic relationship: capable_of GO:0007271 ! synaptic transmission, cholinergic [Term] id: GO:0099003 name: vesicle-mediated transport in synapse namespace: biological_process def: "Any vesicle-mediated transport that occurs in a synapse." [GOC:dos] subset: goslim_synapse is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0016192 ! vesicle-mediated transport intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0099054 name: presynapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a presynapse." [GOC:bf, GOC:dos, GOC:PARL, PMID:24449494] subset: goslim_synapse synonym: "presynapse biogenesis" EXACT [GOC:mah] synonym: "presynaptic terminal assembly" EXACT [PMID:24449494] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099172 ! presynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0098793 ! presynapse relationship: part_of GO:0007416 ! synapse assembly relationship: results_in_assembly_of GO:0098793 ! presynapse [Term] id: GO:0099068 name: postsynapse assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:bf, GOC:dos, GOCL:PARL] synonym: "postsynapse biogenesis" EXACT [GOC:mah] is_a: GO:0022607 ! cellular component assembly is_a: GO:0099173 ! postsynapse organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_assembly_of GO:0098794 ! postsynapse relationship: part_of GO:0007416 ! synapse assembly relationship: results_in_assembly_of GO:0098794 ! postsynapse [Term] id: GO:0099080 name: supramolecular complex namespace: cellular_component def: "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." [GOC:dos] is_a: GO:0110165 ! cellular anatomical entity [Term] id: GO:0099081 name: supramolecular polymer namespace: cellular_component def: "A polymeric supramolecular structure." [GOC:dos] is_a: GO:0099080 ! supramolecular complex intersection_of: GO:0099080 ! supramolecular complex intersection_of: has_characteristic PATO:0015006 ! polymeric relationship: has_characteristic PATO:0015006 ! polymeric [Term] id: GO:0099082 name: retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] subset: goslim_synapse is_a: GO:0098917 ! retrograde trans-synaptic signaling is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse intersection_of: process_has_causal_agent CHEBI:16670 ! peptide [Term] id: GO:0099083 name: retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission namespace: biological_process def: "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." [GOC:bf, GOC:dos, GOC:PARL, PMID:19448629] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide is_a: GO:0099551 ! trans-synaptic signaling by neuropeptide, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: has_end_location GO:0098793 ! presynapse intersection_of: has_start_location GO:0098794 ! postsynapse intersection_of: process_has_causal_agent CHEBI:16670 ! peptide intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099098 name: microtubule polymerization based movement namespace: biological_process def: "The movement of a cellular component as a result of microtubule polymerization." [GOC:cjm, ISBN:0815316194] is_a: GO:0007018 ! microtubule-based movement intersection_of: GO:0007018 ! microtubule-based movement intersection_of: has_part GO:0046785 ! microtubule polymerization relationship: has_part GO:0046785 ! microtubule polymerization [Term] id: GO:0099111 name: microtubule-based transport namespace: biological_process def: "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." [GOC:cjm, ISBN:0815316194] is_a: GO:0006810 ! transport intersection_of: GO:0006810 ! transport intersection_of: process_has_causal_agent GO:0005874 ! microtubule relationship: process_has_causal_agent GO:0005874 ! microtubule [Term] id: GO:0099112 name: microtubule polymerization based protein transport namespace: biological_process def: "The transport of a protein driven by polymerization of a microtubule to which it is attached." [GOC:dos, GOC:vw, PMID:11018050] is_a: GO:0006886 ! intracellular protein transport is_a: GO:0099118 ! microtubule-based protein transport intersection_of: GO:0046907 ! intracellular transport intersection_of: has_part GO:0046785 ! microtubule polymerization intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: process_has_causal_agent GO:0005874 ! microtubule relationship: has_part GO:0046785 ! microtubule polymerization [Term] id: GO:0099118 name: microtubule-based protein transport namespace: biological_process def: "A microtubule-based process that results in the transport of proteins." [GOC:vw] is_a: GO:0007017 ! microtubule-based process is_a: GO:0015031 ! protein transport is_a: GO:0099111 ! microtubule-based transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: process_has_causal_agent GO:0005874 ! microtubule [Term] id: GO:0099140 name: presynaptic actin cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0030036 ! actin cytoskeleton organization is_a: GO:0099187 ! presynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0099143 ! presynaptic actin cytoskeleton relationship: results_in_organization_of GO:0099143 ! presynaptic actin cytoskeleton created_by: dos creation_date: 2017-06-09T18:34:19Z [Term] id: GO:0099143 name: presynaptic actin cytoskeleton namespace: cellular_component def: "The actin cytoskeleton that is part of a presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0015629 ! actin cytoskeleton is_a: GO:0099569 ! presynaptic cytoskeleton intersection_of: GO:0015629 ! actin cytoskeleton intersection_of: part_of GO:0098793 ! presynapse created_by: dos creation_date: 2017-06-09T18:36:19Z [Term] id: GO:0099156 name: cell-cell signaling via exosome namespace: biological_process def: "Cell-cell signaling in which the ligand is carried between cells by an exosome." [GOC:dos, PMID:19837038] synonym: "exosome mediated" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: process_has_causal_agent GO:0070062 ! extracellular exosome relationship: process_has_causal_agent GO:0070062 ! extracellular exosome created_by: dos creation_date: 2017-07-05T16:40:45Z [Term] id: GO:0099157 name: trans-synaptic signalling via exosome namespace: biological_process def: "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." [GOC:dos, PMID:19837038] subset: goslim_synapse synonym: "exosome mediated transynaptic signalling" EXACT [] is_a: GO:0099156 ! cell-cell signaling via exosome is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent GO:0070062 ! extracellular exosome created_by: dos creation_date: 2017-07-05T16:49:44Z [Term] id: GO:0099160 name: postsynaptic intermediate filament cytoskeleton namespace: cellular_component def: "The intermediate filament cytoskeleton that is part of a postsynapse." [GOC:dos, PMID:25869803] subset: goslim_synapse is_a: GO:0045111 ! intermediate filament cytoskeleton is_a: GO:0099571 ! postsynaptic cytoskeleton intersection_of: GO:0045111 ! intermediate filament cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse created_by: dos creation_date: 2017-08-28T15:26:08Z [Term] id: GO:0099170 name: postsynaptic modulation of chemical synaptic transmission namespace: biological_process def: "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." [GOC:dos] subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse created_by: dos creation_date: 2017-09-11T17:09:17Z [Term] id: GO:0099171 name: presynaptic modulation of chemical synaptic transmission namespace: biological_process def: "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." [GOC:dos] subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse created_by: dos creation_date: 2017-09-11T17:09:31Z [Term] id: GO:0099172 name: presynapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." [GOC:dos] subset: goslim_synapse synonym: "presynapse development" EXACT [] synonym: "presynapse morphogenesis" RELATED [GOC:BHF] synonym: "presynapse organisation" EXACT [] synonym: "presynapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0098793 ! presynapse relationship: part_of GO:0050808 ! synapse organization relationship: results_in_organization_of GO:0098793 ! presynapse [Term] id: GO:0099173 name: postsynapse organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." [GOC:dos] subset: goslim_synapse synonym: "postsynapse development" EXACT [] synonym: "postsynapse morphogenesis" RELATED [GOC:BHF] synonym: "postsynapse organisation" EXACT [] synonym: "postsynapse organization and biogenesis" RELATED [GOC:mah] is_a: GO:0016043 ! cellular component organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0098794 ! postsynapse relationship: part_of GO:0050808 ! synapse organization relationship: results_in_organization_of GO:0098794 ! postsynapse [Term] id: GO:0099174 name: regulation of presynapse organization namespace: biological_process def: "Any process that modulates the physical form of a presynapse." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of presynapse organisation" EXACT [GOC:mah] synonym: "regulation of presynapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of presynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099172 ! presynapse organization relationship: regulates GO:0099172 ! presynapse organization [Term] id: GO:0099175 name: regulation of postsynapse organization namespace: biological_process def: "Any process that modulates the physical form of a postsynapse." [GOC:ai, GOC:dph, GOC:tb] subset: goslim_synapse synonym: "regulation of postsynapse organisation" EXACT [GOC:mah] synonym: "regulation of postsynapse organization and biogenesis" RELATED [GOC:mah] synonym: "regulation of postsynapse structure" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099173 ! postsynapse organization relationship: regulates GO:0099173 ! postsynapse organization [Term] id: GO:0099177 name: regulation of trans-synaptic signaling namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." [GOC:dos] is_a: GO:0010646 ! regulation of cell communication is_a: GO:0023051 ! regulation of signaling intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099537 ! trans-synaptic signaling relationship: regulates GO:0099537 ! trans-synaptic signaling [Term] id: GO:0099182 name: presynaptic intermediate filament cytoskeleton namespace: cellular_component def: "The intermediate filament cytoskeleton that is part of a presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0045111 ! intermediate filament cytoskeleton is_a: GO:0099569 ! presynaptic cytoskeleton intersection_of: GO:0045111 ! intermediate filament cytoskeleton intersection_of: part_of GO:0098793 ! presynapse created_by: dos creation_date: 2017-12-01T18:10:21Z [Term] id: GO:0099185 name: postsynaptic intermediate filament cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0045104 ! intermediate filament cytoskeleton organization is_a: GO:0099188 ! postsynaptic cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0099160 ! postsynaptic intermediate filament cytoskeleton relationship: results_in_organization_of GO:0099160 ! postsynaptic intermediate filament cytoskeleton created_by: dos creation_date: 2017-12-20T13:47:30Z [Term] id: GO:0099187 name: presynaptic cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." [GOC:dos] is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0009987 ! cellular process intersection_of: results_in_organization_of GO:0099569 ! presynaptic cytoskeleton relationship: part_of GO:0099172 ! presynapse organization relationship: results_in_organization_of GO:0099569 ! presynaptic cytoskeleton created_by: dos creation_date: 2017-12-20T15:05:34Z [Term] id: GO:0099188 name: postsynaptic cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." [GOC:dos] subset: goslim_synapse is_a: GO:0007010 ! cytoskeleton organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0099571 ! postsynaptic cytoskeleton relationship: part_of GO:0099173 ! postsynapse organization relationship: results_in_organization_of GO:0099571 ! postsynaptic cytoskeleton created_by: dos creation_date: 2017-12-20T15:06:57Z [Term] id: GO:0099500 name: vesicle fusion to plasma membrane namespace: biological_process def: "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." [GOC:aruk, GOC:bc, ISBN:0071120009, PMID:18618940] is_a: GO:0006906 ! vesicle fusion is_a: GO:0140029 ! exocytic process intersection_of: GO:0061025 ! membrane fusion intersection_of: part_of GO:0006887 ! exocytosis intersection_of: results_in_fusion_of GO:0012506 ! vesicle membrane intersection_of: results_in_fusion_of GO:0098590 ! plasma membrane region relationship: results_in_fusion_of GO:0098590 ! plasma membrane region [Term] id: GO:0099501 name: exocytic vesicle membrane namespace: cellular_component def: "The lipid bilayer surrounding an exocytic vesicle." [GOC:dos] synonym: "secretory vesicle membrane" BROAD [] is_a: GO:0030658 ! transport vesicle membrane intersection_of: GO:0016020 ! membrane intersection_of: bounding_layer_of GO:0070382 ! exocytic vesicle relationship: bounding_layer_of GO:0070382 ! exocytic vesicle relationship: part_of GO:0070382 ! exocytic vesicle [Term] id: GO:0099503 name: secretory vesicle namespace: cellular_component def: "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." [GOC:dos] subset: goslim_drosophila is_a: GO:0031410 ! cytoplasmic vesicle intersection_of: GO:0031982 ! vesicle intersection_of: capable_of GO:0099500 ! vesicle fusion to plasma membrane relationship: capable_of GO:0099500 ! vesicle fusion to plasma membrane [Term] id: GO:0099512 name: supramolecular fiber namespace: cellular_component alt_id: GO:0043205 def: "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." [GOC:dos] synonym: "fibril" RELATED [] is_a: GO:0099081 ! supramolecular polymer intersection_of: GO:0099080 ! supramolecular complex intersection_of: has_characteristic PATO:0002309 ! fiber shaped intersection_of: has_characteristic PATO:0015006 ! polymeric relationship: has_characteristic PATO:0002309 ! fiber shaped [Term] id: GO:0099513 name: polymeric cytoskeletal fiber namespace: cellular_component def: "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." [GOC:dos] is_a: GO:0099512 ! supramolecular fiber intersection_of: GO:0099512 ! supramolecular fiber intersection_of: has_characteristic PATO:0015006 ! polymeric intersection_of: part_of GO:0005856 ! cytoskeleton relationship: part_of GO:0005856 ! cytoskeleton [Term] id: GO:0099515 name: actin filament-based transport namespace: biological_process def: "The transport of organelles or other particles from one location in the cell to another along actin filaments." [GOC:dos, GOC:dph, GOC:mah, GOC:tb] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport intersection_of: GO:0046907 ! intracellular transport intersection_of: results_in_transport_along GO:0005884 ! actin filament relationship: results_in_transport_along GO:0005884 ! actin filament created_by: tb creation_date: 2009-05-27T10:56:08Z [Term] id: GO:0099518 name: vesicle cytoskeletal trafficking namespace: biological_process def: "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." [GOC:ecd, GOC:rl] synonym: "cytoskeletal fiber-based vesicle localization" EXACT [GOC:rl] synonym: "vesicle cytoskeletal transport" EXACT [] is_a: GO:0030705 ! cytoskeleton-dependent intracellular transport is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input GO:0031982 ! vesicle intersection_of: results_in_transport_along GO:0099513 ! polymeric cytoskeletal fiber [Term] id: GO:0099531 name: presynaptic process involved in chemical synaptic transmission namespace: biological_process def: "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." [GOC:dos] subset: gocheck_do_not_annotate subset: goslim_synapse is_a: GO:0050877 ! nervous system process intersection_of: GO:0050877 ! nervous system process intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: part_of GO:0007268 ! chemical synaptic transmission relationship: occurs_in GO:0098793 ! presynapse relationship: part_of GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099536 name: synaptic signaling namespace: biological_process def: "Cell-cell signaling to, from or within a synapse." [GOC:dos] subset: goslim_drosophila subset: goslim_synapse is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa [Term] id: GO:0099537 name: trans-synaptic signaling namespace: biological_process def: "Cell-cell signaling in either direction across the synaptic cleft." [GOC:dos] subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling [Term] id: GO:0099538 name: synaptic signaling via neuropeptide namespace: biological_process def: "Cell-cell signaling to or from a synapse, mediated by a peptide." [GOC:dos] subset: goslim_synapse is_a: GO:0099536 ! synaptic signaling intersection_of: GO:0099536 ! synaptic signaling intersection_of: process_has_causal_agent CHEBI:16670 ! peptide relationship: process_has_causal_agent CHEBI:16670 ! peptide [Term] id: GO:0099540 name: trans-synaptic signaling by neuropeptide namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." [GOC:dos] subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling is_a: GO:0099538 ! synaptic signaling via neuropeptide intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:16670 ! peptide [Term] id: GO:0099541 name: trans-synaptic signaling by lipid namespace: biological_process def: "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." [GOC:dos] subset: goslim_synapse is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:18059 ! lipid relationship: process_has_causal_agent CHEBI:18059 ! lipid [Term] id: GO:0099546 name: protein catabolic process, modulating synaptic transmission namespace: biological_process def: "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." [GOC:dos, PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099547 name: regulation of translation at synapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0006412 ! translation intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa [Term] id: GO:0099550 name: trans-synaptic signaling, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0099537 ! trans-synaptic signaling intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099551 name: trans-synaptic signaling by neuropeptide, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099540 ! trans-synaptic signaling by neuropeptide is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:16670 ! peptide intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099552 name: trans-synaptic signaling by lipid, modulating synaptic transmission namespace: biological_process def: "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." [GOC:dos, PMID:21531987] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099541 ! trans-synaptic signaling by lipid is_a: GO:0099550 ! trans-synaptic signaling, modulating synaptic transmission intersection_of: GO:0099537 ! trans-synaptic signaling intersection_of: process_has_causal_agent CHEBI:18059 ! lipid intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099568 name: cytoplasmic region namespace: cellular_component def: "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." [GOC:dos] subset: gocheck_do_not_annotate is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm [Term] id: GO:0099569 name: presynaptic cytoskeleton namespace: cellular_component def: "The portion of the cytoskeleton contained within the presynapse." [GOC:dos] subset: goslim_synapse is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: part_of GO:0098793 ! presynapse relationship: part_of GO:0098793 ! presynapse [Term] id: GO:0099571 name: postsynaptic cytoskeleton namespace: cellular_component def: "The portion of the cytoskeleton contained within the postsynapse." [GOC:dos, PMID:19889835] subset: goslim_synapse is_a: GO:0005856 ! cytoskeleton intersection_of: GO:0005856 ! cytoskeleton intersection_of: part_of GO:0098794 ! postsynapse relationship: part_of GO:0098794 ! postsynapse [Term] id: GO:0099574 name: regulation of protein catabolic process at synapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0050804 ! modulation of chemical synaptic transmission is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: has_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission intersection_of: regulates GO:0009056 ! catabolic process relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa [Term] id: GO:0099575 name: regulation of protein catabolic process at presynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099576 name: regulation of protein catabolic process at postsynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0042176 ! regulation of protein catabolic process is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission intersection_of: GO:0042176 ! regulation of protein catabolic process intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099577 name: regulation of translation at presynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099171 ! presynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140244 ! regulation of translation at presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0006412 ! translation intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099578 name: regulation of translation at postsynapse, modulating synaptic transmission namespace: biological_process def: "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." [GOC:dos] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0099170 ! postsynaptic modulation of chemical synaptic transmission is_a: GO:0099547 ! regulation of translation at synapse, modulating synaptic transmission is_a: GO:0140245 ! regulation of translation at postsynapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0006412 ! translation intersection_of: regulates GO:0007268 ! chemical synaptic transmission [Term] id: GO:0099612 name: protein localization to axon namespace: biological_process def: "A process in which a protein is transported to or maintained in a location within an axon." [GOC:dos, PMID:26157139] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0030424 ! axon relationship: has_target_end_location GO:0030424 ! axon [Term] id: GO:0099632 name: protein transport within plasma membrane namespace: biological_process def: "A process in which protein is transported from one region of the plasma membrane to another." [GOC:dos] is_a: GO:0032594 ! protein transport within lipid bilayer intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0005886 ! plasma membrane relationship: occurs_in GO:0005886 ! plasma membrane [Term] id: GO:0099640 name: axo-dendritic protein transport namespace: biological_process def: "The directed movement of proteins along microtubules in neuron projections." [ISBN:0815316194] subset: goslim_synapse synonym: "axonal protein transport" NARROW [] is_a: GO:0008088 ! axo-dendritic transport is_a: GO:0098840 ! protein transport along microtubule intersection_of: GO:0046907 ! intracellular transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: occurs_in GO:0043005 ! neuron projection intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0099641 name: anterograde axonal protein transport namespace: biological_process def: "The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons." [GOC:dos] subset: goslim_synapse synonym: "anterograde axon cargo transport" BROAD [] is_a: GO:0008089 ! anterograde axonal transport is_a: GO:0099640 ! axo-dendritic protein transport is_a: GO:1905383 ! protein localization to presynapse intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: has_target_end_location GO:0098793 ! presynapse intersection_of: occurs_in GO:1904115 ! axon cytoplasm intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0099642 name: retrograde axonal protein transport namespace: biological_process def: "The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons." [ISBN:0815316194] subset: goslim_synapse synonym: "retrograde axon cargo transport" BROAD [] is_a: GO:0008090 ! retrograde axonal transport is_a: GO:0099640 ! axo-dendritic protein transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input PR:000000001 ! protein intersection_of: has_target_start_location GO:0098793 ! presynapse intersection_of: occurs_in GO:1904115 ! axon cytoplasm intersection_of: results_in_transport_along GO:0005874 ! microtubule [Term] id: GO:0099643 name: signal release from synapse namespace: biological_process def: "Any signal release from a synapse." [GOC:dos] subset: goslim_synapse is_a: GO:0023061 ! signal release intersection_of: GO:0023061 ! signal release intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of GO:0099536 ! synaptic signaling [Term] id: GO:0099738 name: cell cortex region namespace: cellular_component def: "The complete extent of cell cortex that underlies some some region of the plasma membrane." [GOC:dos] subset: gocheck_do_not_annotate synonym: "perimembrane region" EXACT [] is_a: GO:0005938 ! cell cortex is_a: GO:0099568 ! cytoplasmic region intersection_of: GO:0005938 ! cell cortex intersection_of: part_of GO:0005938 ! cell cortex relationship: part_of GO:0005938 ! cell cortex [Term] id: GO:0100001 name: regulation of skeletal muscle contraction by action potential namespace: biological_process def: "Any action potential process that regulates skeletal muscle contraction." [GOC:cjm, GOC:obol] is_a: BFO:0000015 ! process is_a: GO:0001508 ! action potential is_a: http://rs.tdwg.org/dwc/terms/Event ! Event intersection_of: GO:0001508 ! action potential intersection_of: regulates GO:0003009 ! skeletal muscle contraction relationship: regulates GO:0003009 ! skeletal muscle contraction created_by: cjm creation_date: 2015-04-02T04:13:19Z [Term] id: GO:0101023 name: vascular endothelial cell proliferation namespace: biological_process def: "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." [GOC:BHF, GOC:BHF_telomere, GOC:nc, PMID:23201774] is_a: GO:0001935 ! endothelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000071 ! blood vessel endothelial cell relationship: acts_on_population_of CL:0000071 ! blood vessel endothelial cell [Term] id: GO:0101024 name: mitotic nuclear membrane organization namespace: biological_process def: "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." [GOC:vw, PMID:15147872] comment: This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown. synonym: "nuclear membrane organization involved in mitotic nuclear division" EXACT [] is_a: GO:0071763 ! nuclear membrane organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0071763 ! nuclear membrane organization intersection_of: part_of GO:0140014 ! mitotic nuclear division relationship: in_taxon NCBITaxon:2759 {all_only="true"} ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: part_of GO:0140014 ! mitotic nuclear division property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19949" xsd:anyURI [Term] id: GO:0101025 name: nuclear membrane biogenesis namespace: biological_process def: "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." [GOC:vw] is_a: GO:0044091 ! membrane biogenesis intersection_of: GO:0044085 ! cellular component biogenesis intersection_of: has_output GO:0031965 ! nuclear membrane relationship: has_output GO:0031965 ! nuclear membrane relationship: part_of GO:0071763 ! nuclear membrane organization [Term] id: GO:0106027 name: neuron projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." [GOC:aruk, GOC:bc, PMID:11585923] is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0043005 ! neuron projection relationship: results_in_organization_of GO:0043005 ! neuron projection created_by: hjd creation_date: 2017-06-23T18:30:18Z [Term] id: GO:0106214 name: regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031338 ! regulation of vesicle fusion is_a: GO:1903358 ! regulation of Golgi organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048280 ! vesicle fusion with Golgi apparatus relationship: regulates GO:0048280 ! vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:12:22Z [Term] id: GO:0106215 name: negative regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031339 ! negative regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus relationship: negatively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:17:17Z [Term] id: GO:0106216 name: positive regulation of vesicle fusion with Golgi apparatus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." [GOC:se, PMID:26195667] is_a: GO:0031340 ! positive regulation of vesicle fusion is_a: GO:0106214 ! regulation of vesicle fusion with Golgi apparatus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus relationship: positively_regulates GO:0048280 ! vesicle fusion with Golgi apparatus created_by: hjd creation_date: 2019-06-27T15:20:59Z [Term] id: GO:0110011 name: regulation of basement membrane organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." [GOC:ha, PMID:27404358] is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071711 ! basement membrane organization relationship: regulates GO:0071711 ! basement membrane organization created_by: kmv [Term] id: GO:0110020 name: regulation of actomyosin structure organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." [GOC:lf, PMID:22790195] is_a: GO:0032956 ! regulation of actin cytoskeleton organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031032 ! actomyosin structure organization relationship: regulates GO:0031032 ! actomyosin structure organization created_by: kmv creation_date: 2017-06-20T19:28:58Z [Term] id: GO:0110021 name: cardiac muscle myoblast proliferation namespace: biological_process def: "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0051450 ! myoblast proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000513 ! cardiac muscle myoblast relationship: acts_on_population_of CL:0000513 ! cardiac muscle myoblast created_by: kmv creation_date: 2017-06-29T14:35:24Z [Term] id: GO:0110022 name: regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0110021 ! cardiac muscle myoblast proliferation relationship: regulates GO:0110021 ! cardiac muscle myoblast proliferation created_by: kmv creation_date: 2017-06-29T15:11:47Z [Term] id: GO:0110023 name: negative regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000818 ! negative regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation relationship: negatively_regulates GO:0110021 ! cardiac muscle myoblast proliferation created_by: kmv creation_date: 2017-06-29T15:18:30Z [Term] id: GO:0110024 name: positive regulation of cardiac muscle myoblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:26512644] is_a: GO:0110022 ! regulation of cardiac muscle myoblast proliferation is_a: GO:2000288 ! positive regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation relationship: positively_regulates GO:0110021 ! cardiac muscle myoblast proliferation created_by: kmv creation_date: 2017-06-29T15:24:16Z [Term] id: GO:0110040 name: pharynx morphogenesis namespace: biological_process def: "The process in which the anatomical structures of the pharynx are generated and organized." [GOC:rz, PMID:20805556] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0006562 ! pharynx relationship: results_in_morphogenesis_of UBERON:0006562 ! pharynx created_by: kmv creation_date: 2017-07-24T20:51:28Z [Term] id: GO:0110041 name: regulation of pharynx morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized." [GOC:rz, PMID:20805556] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0110040 ! pharynx morphogenesis relationship: regulates GO:0110040 ! pharynx morphogenesis created_by: kmv creation_date: 2017-07-24T21:00:20Z [Term] id: GO:0110042 name: negative regulation of pharynx morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis." [GOC:rz, PMID:20805556] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0110041 ! regulation of pharynx morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0110040 ! pharynx morphogenesis relationship: negatively_regulates GO:0110040 ! pharynx morphogenesis created_by: kmv creation_date: 2017-07-24T21:05:08Z [Term] id: GO:0110043 name: positive regulation of pharynx morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis." [GOC:rz, PMID:20805556] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0110041 ! regulation of pharynx morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0110040 ! pharynx morphogenesis relationship: positively_regulates GO:0110040 ! pharynx morphogenesis created_by: kmv creation_date: 2017-07-24T21:09:48Z [Term] id: GO:0110053 name: regulation of actin filament organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin filament organization." [GOC:kmv] is_a: GO:0032956 ! regulation of actin cytoskeleton organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007015 ! actin filament organization relationship: regulates GO:0007015 ! actin filament organization created_by: kmv creation_date: 2017-09-20T19:52:57Z [Term] id: GO:0110057 name: regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045601 ! regulation of endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060837 ! blood vessel endothelial cell differentiation relationship: regulates GO:0060837 ! blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:32:09Z [Term] id: GO:0110058 name: positive regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045603 ! positive regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation relationship: positively_regulates GO:0060837 ! blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:38:19Z [Term] id: GO:0110059 name: negative regulation of blood vessel endothelial cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:23072816] is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:0110057 ! regulation of blood vessel endothelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation relationship: negatively_regulates GO:0060837 ! blood vessel endothelial cell differentiation created_by: kmv creation_date: 2017-10-23T14:47:29Z [Term] id: GO:0110077 name: vesicle-mediated intercellular transport namespace: biological_process def: "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." [GOC:sp, PMID:29328915, PMID:29328916] is_a: GO:0010496 ! intercellular transport is_a: GO:0016192 ! vesicle-mediated transport intersection_of: GO:0010496 ! intercellular transport intersection_of: process_has_causal_agent GO:1903561 ! extracellular vesicle relationship: process_has_causal_agent GO:1903561 ! extracellular vesicle created_by: kmv creation_date: 2018-01-29T14:46:52Z [Term] id: GO:0110079 name: regulation of placenta blood vessel development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060674 ! placenta blood vessel development relationship: regulates GO:0060674 ! placenta blood vessel development created_by: kmv creation_date: 2018-02-01T14:49:12Z [Term] id: GO:0110080 name: positive regulation of placenta blood vessel development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060674 ! placenta blood vessel development relationship: positively_regulates GO:0060674 ! placenta blood vessel development created_by: kmv creation_date: 2018-02-01T14:55:30Z [Term] id: GO:0110081 name: negative regulation of placenta blood vessel development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27748453] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0110079 ! regulation of placenta blood vessel development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060674 ! placenta blood vessel development relationship: negatively_regulates GO:0060674 ! placenta blood vessel development created_by: kmv creation_date: 2018-02-01T15:01:11Z [Term] id: GO:0110110 name: positive regulation of animal organ morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009887 ! animal organ morphogenesis relationship: positively_regulates GO:0009887 ! animal organ morphogenesis created_by: kmv creation_date: 2018-07-05T14:10:14Z [Term] id: GO:0110111 name: negative regulation of animal organ morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." [GOC:kmv] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009887 ! animal organ morphogenesis relationship: negatively_regulates GO:0009887 ! animal organ morphogenesis created_by: kmv creation_date: 2018-07-05T14:25:21Z [Term] id: GO:0110112 name: regulation of lipid transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: term_scheduled_for_obsoletion is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0032409 ! regulation of transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0005319 ! lipid transporter activity relationship: regulates GO:0005319 ! lipid transporter activity created_by: kmv creation_date: 2018-07-06T18:53:55Z [Term] id: GO:0110113 name: positive regulation of lipid transporter activity namespace: biological_process def: "Any process that increases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: term_scheduled_for_obsoletion is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0032411 ! positive regulation of transporter activity is_a: GO:0110112 ! regulation of lipid transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0005319 ! lipid transporter activity relationship: positively_regulates GO:0005319 ! lipid transporter activity created_by: kmv creation_date: 2018-07-06T19:14:13Z [Term] id: GO:0110114 name: negative regulation of lipid transporter activity namespace: biological_process def: "Any process that decreases the frequency, rate, or extent of lipid transporter activity." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:27365390] subset: term_scheduled_for_obsoletion is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0032410 ! negative regulation of transporter activity is_a: GO:0110112 ! regulation of lipid transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0005319 ! lipid transporter activity relationship: negatively_regulates GO:0005319 ! lipid transporter activity created_by: kmv creation_date: 2018-07-06T19:21:44Z [Term] id: GO:0110116 name: regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046532 ! regulation of photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001751 ! compound eye photoreceptor cell differentiation relationship: regulates GO:0001751 ! compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:08:49Z [Term] id: GO:0110117 name: positive regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046534 ! positive regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation relationship: positively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:13:28Z [Term] id: GO:0110118 name: negative regulation of compound eye photoreceptor cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." [GOC:ha, PMID:16377567] is_a: GO:0046533 ! negative regulation of photoreceptor cell differentiation is_a: GO:0110116 ! regulation of compound eye photoreceptor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation relationship: negatively_regulates GO:0001751 ! compound eye photoreceptor cell differentiation created_by: kmv creation_date: 2018-07-16T18:15:52Z [Term] id: GO:0110122 name: myotube cell migration namespace: biological_process def: "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." [GOC:ha, PMID:29122742] is_a: GO:0014812 ! muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0002372 ! myotube relationship: results_in_movement_of CL:0002372 ! myotube created_by: kmv creation_date: 2018-08-22T20:58:09Z [Term] id: GO:0110123 name: regulation of myotube cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0110122 ! myotube cell migration relationship: regulates GO:0110122 ! myotube cell migration created_by: kmv creation_date: 2018-08-22T21:06:53Z [Term] id: GO:0110124 name: positive regulation of myotube cell migration namespace: biological_process def: "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0110122 ! myotube cell migration relationship: positively_regulates GO:0110122 ! myotube cell migration created_by: kmv creation_date: 2018-08-22T21:09:38Z [Term] id: GO:0110125 name: negative regulation of myotube cell migration namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." [GOC:ha, PMID:29122742] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0110123 ! regulation of myotube cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0110122 ! myotube cell migration relationship: negatively_regulates GO:0110122 ! myotube cell migration created_by: kmv creation_date: 2018-08-22T21:12:47Z [Term] id: GO:0110165 name: cellular anatomical entity namespace: cellular_component def: "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." [GOC:kmv] subset: goslim_pir is_a: CARO:0000000 ! anatomical entity is_a: GO:0005575 ! cellular_component created_by: kmv creation_date: 2019-08-12T18:01:37Z [Term] id: GO:0120025 name: plasma membrane bounded cell projection namespace: cellular_component def: "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] is_a: GO:0042995 ! cell projection intersection_of: GO:0042995 ! cell projection intersection_of: has_part GO:0098590 ! plasma membrane region relationship: has_part GO:0098590 ! plasma membrane region property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13193" xsd:anyURI created_by: krc creation_date: 2017-03-21T17:26:07Z [Term] id: GO:0120031 name: plasma membrane bounded cell projection assembly namespace: biological_process def: "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." [GOC:krc] synonym: "eupodium" NARROW [GOC:krc, GOC:rjd, PMID:10328951, PMID:9096956] is_a: GO:0030031 ! cell projection assembly is_a: GO:0120036 ! plasma membrane bounded cell projection organization intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0120025 ! plasma membrane bounded cell projection relationship: results_in_assembly_of GO:0120025 ! plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-24T23:56:08Z [Term] id: GO:0120032 name: regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0060491 ! regulation of cell projection assembly is_a: GO:0120035 ! regulation of plasma membrane bounded cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0120031 ! plasma membrane bounded cell projection assembly relationship: regulates GO:0120031 ! plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:27:04Z [Term] id: GO:0120033 name: negative regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031345 ! negative regulation of cell projection organization is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly relationship: negatively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:34:31Z [Term] id: GO:0120034 name: positive regulation of plasma membrane bounded cell projection assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." [GOC:krc] is_a: GO:0031346 ! positive regulation of cell projection organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly relationship: positively_regulates GO:0120031 ! plasma membrane bounded cell projection assembly property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T04:34:45Z [Term] id: GO:0120035 name: regulation of plasma membrane bounded cell projection organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." [GOC:krc] is_a: GO:0031344 ! regulation of cell projection organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0120036 ! plasma membrane bounded cell projection organization relationship: regulates GO:0120036 ! plasma membrane bounded cell projection organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T16:02:06Z [Term] id: GO:0120036 name: plasma membrane bounded cell projection organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." [GOC:krc] is_a: GO:0030030 ! cell projection organization intersection_of: GO:0016043 ! cellular component organization intersection_of: results_in_organization_of GO:0120025 ! plasma membrane bounded cell projection relationship: results_in_organization_of GO:0120025 ! plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-26T16:07:02Z [Term] id: GO:0120039 name: plasma membrane bounded cell projection morphogenesis namespace: biological_process def: "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." [GOC:krc] is_a: GO:0048858 ! cell projection morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of GO:0120025 ! plasma membrane bounded cell projection relationship: results_in_morphogenesis_of GO:0120025 ! plasma membrane bounded cell projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/13298" xsd:anyURI created_by: krc creation_date: 2017-04-28T23:39:37Z [Term] id: GO:0120111 name: neuron projection cytoplasm namespace: cellular_component def: "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." [GOC:ha] is_a: GO:0032838 ! plasma membrane bounded cell projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0043005 ! neuron projection relationship: part_of GO:0043005 ! neuron projection property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14472" xsd:anyURI created_by: krc creation_date: 2017-11-01T18:58:12Z [Term] id: GO:0120158 name: positive regulation of collagen catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." [GOC:dph, GOC:tb] synonym: "activation of collagen catabolic process" NARROW [GOC:dph, GOC:tb] synonym: "positive regulation of collagen breakdown" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen catabolism" EXACT [GOC:dph, GOC:tb] synonym: "positive regulation of collagen degradation" EXACT [GOC:dph, GOC:tb] synonym: "up regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "up-regulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] synonym: "upregulation of collagen catabolic process" EXACT [GOC:dph, GOC:tb] is_a: GO:0009896 ! positive regulation of catabolic process is_a: GO:0010710 ! regulation of collagen catabolic process is_a: GO:0010714 ! positive regulation of collagen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030574 ! collagen catabolic process relationship: positively_regulates GO:0030574 ! collagen catabolic process property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15720" xsd:anyURI created_by: krc creation_date: 2018-05-11T16:31:42Z [Term] id: GO:0120178 name: steroid hormone biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." [GOC:krc, GOC:nln] is_a: GO:0006694 ! steroid biosynthetic process intersection_of: GO:0006694 ! steroid biosynthetic process intersection_of: has_output CHEBI:26764 ! steroid hormone relationship: has_output CHEBI:26764 ! steroid hormone property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16000" xsd:anyURI created_by: krc creation_date: 2019-05-20T22:34:00Z [Term] id: GO:0120186 name: negative regulation of protein localization to chromatin namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "negative regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071168 ! protein localization to chromatin relationship: negatively_regulates GO:0071168 ! protein localization to chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI created_by: krc creation_date: 2018-07-14T00:19:32Z [Term] id: GO:0120187 name: positive regulation of protein localization to chromatin namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." [PMID:20889714, PMID:29899453] synonym: "positive regulation of protein localisation to chromatin" EXACT [GOC:krc] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905634 ! regulation of protein localization to chromatin intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071168 ! protein localization to chromatin relationship: positively_regulates GO:0071168 ! protein localization to chromatin property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16012" xsd:anyURI created_by: krc creation_date: 2018-07-14T00:21:28Z [Term] id: GO:0120188 name: regulation of bile acid secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032782 ! bile acid secretion relationship: regulates GO:0032782 ! bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:28:58Z [Term] id: GO:0120189 name: positive regulation of bile acid secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032782 ! bile acid secretion relationship: positively_regulates GO:0032782 ! bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:36:17Z [Term] id: GO:0120190 name: negative regulation of bile acid secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." [GOC:BHF, GOC:BHF_miRNA, GOC:rph, PMID:22767443] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0120188 ! regulation of bile acid secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032782 ! bile acid secretion relationship: negatively_regulates GO:0032782 ! bile acid secretion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/16040" xsd:anyURI created_by: krc creation_date: 2018-07-16T22:38:34Z [Term] id: GO:0120222 name: regulation of blastocyst development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blastocyst development." [GOC:krc, PMID:29593216] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001824 ! blastocyst development relationship: regulates GO:0001824 ! blastocyst development property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18871" xsd:anyURI created_by: krc creation_date: 2020-02-17T19:59:20Z [Term] id: GO:0120223 name: larynx morphogenesis namespace: biological_process def: "The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." [GOC:krc, PMID:28177282] synonym: "laryngeal morphogenesis" EXACT [GOC:krc, PMID:28177282] is_a: GO:0009887 ! animal organ morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001737 ! larynx relationship: part_of GO:0120224 ! larynx development relationship: results_in_morphogenesis_of UBERON:0001737 ! larynx property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18924" xsd:anyURI created_by: krc creation_date: 2020-02-22T01:42:04Z [Term] id: GO:0120224 name: larynx development namespace: biological_process def: "The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." [GOC:krc, PMID:28177282] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001737 ! larynx relationship: part_of GO:0060541 ! respiratory system development relationship: results_in_development_of UBERON:0001737 ! larynx property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/18924" xsd:anyURI created_by: krc creation_date: 2020-02-24T17:13:10Z [Term] id: GO:0120229 name: protein localization to motile cilium namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a motile cilium." [GOC:krc, PMID:27486780] synonym: "protein localization to nonmotile primary cilium" RELATED [] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0031514 ! motile cilium relationship: has_target_end_location GO:0031514 ! motile cilium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19588" xsd:anyURI created_by: krc creation_date: 2020-06-05T23:43:04Z [Term] id: GO:0120275 name: cerebral blood circulation namespace: biological_process def: "The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products." [GOC:krc, PMID:25397684] synonym: "cerebrum blood circulation" EXACT [] synonym: "telencephelon blood circulation" EXACT [] is_a: GO:0008015 ! blood circulation intersection_of: GO:0008015 ! blood circulation intersection_of: occurs_in UBERON:0001893 ! telencephalon relationship: occurs_in UBERON:0001893 ! telencephalon property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI created_by: krc creation_date: 2020-10-20T19:13:51Z [Term] id: GO:0120276 name: regulation of cerebral blood circulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cerebral blood circulation." [GOC:krc, PMID:25397684] synonym: "regulation of cerebrum blood circulation" EXACT [] synonym: "regulation of telencephalon blood circulation" EXACT [] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0120275 ! cerebral blood circulation relationship: regulates GO:0120275 ! cerebral blood circulation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI created_by: krc creation_date: 2020-10-21T06:52:22Z [Term] id: GO:0120277 name: positive regulation of cerebral blood circulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cerebral blood circulation." [GOC:krc, PMID:25397684] synonym: "activation of cerebral blood circulation" NARROW [] synonym: "positive regulation of cerebrum blood circulation" EXACT [] synonym: "positive regulation of telencephalon blood circulation" EXACT [] synonym: "up regulation of cerebral blood circulation" EXACT [] synonym: "up-regulation of cerebral blood circulation" EXACT [] synonym: "upregulation of cerebral blood circulation" EXACT [] is_a: GO:0120276 ! regulation of cerebral blood circulation is_a: GO:1903524 ! positive regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0120275 ! cerebral blood circulation relationship: positively_regulates GO:0120275 ! cerebral blood circulation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI created_by: krc creation_date: 2020-10-21T06:55:42Z [Term] id: GO:0120278 name: negative regulation of cerebral blood circulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation." [GOC:krc, PMID:25397684] synonym: "down regulation of cerebral blood circulation" EXACT [] synonym: "down-regulation of cerebral blood circulation" EXACT [] synonym: "downregulation of cerebral blood circulation" EXACT [] synonym: "inhibition of cerebral blood circulation" NARROW [] synonym: "negative regulation of cerebrum blood circulation" EXACT [] synonym: "negative regulation of telencephalon blood circulation" EXACT [] is_a: GO:0120276 ! regulation of cerebral blood circulation is_a: GO:1903523 ! negative regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0120275 ! cerebral blood circulation relationship: negatively_regulates GO:0120275 ! cerebral blood circulation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20107" xsd:anyURI created_by: krc creation_date: 2020-10-21T07:02:05Z [Term] id: GO:0120305 name: regulation of pigmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." [GOC:krc] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0043473 ! pigmentation relationship: regulates GO:0043473 ! pigmentation property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20524" xsd:anyURI created_by: krc creation_date: 2021-02-09T19:37:35Z [Term] id: GO:0120316 name: sperm flagellum assembly namespace: biological_process def: "The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium)." [GOC:krc, PMID:32791035] is_a: GO:0003006 ! developmental process involved in reproduction is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:0044458 ! motile cilium assembly intersection_of: GO:0044458 ! motile cilium assembly intersection_of: occurs_in CL:0000019 ! sperm relationship: occurs_in CL:0000019 ! sperm relationship: part_of GO:0007286 ! spermatid development relationship: part_of GO:0030317 ! flagellated sperm motility property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21361" xsd:anyURI created_by: krc creation_date: 2021-04-29T01:27:27Z [Term] id: GO:0120331 name: endothelial tube formation namespace: biological_process def: "The developmental process pertaining to the initial formation of an endothelial tube." [GOC:sl, PMID:23239824] is_a: GO:0072175 ! epithelial tube formation intersection_of: GO:0035148 ! tube formation intersection_of: results_in_formation_of UBERON:0003915 ! endothelial tube relationship: part_of GO:0061154 ! endothelial tube morphogenesis relationship: results_in_formation_of UBERON:0003915 ! endothelial tube property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22302" xsd:anyURI created_by: krc creation_date: 2022-05-25T16:17:59Z [Term] id: GO:0140013 name: meiotic nuclear division namespace: biological_process def: "One of the two nuclear divisions that occur as part of the meiotic cell cycle." [PMID:9334324] subset: goslim_generic synonym: "meiosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0051321 ! meiotic cell cycle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI created_by: pg creation_date: 2017-03-23T09:40:00Z [Term] id: GO:0140014 name: mitotic nuclear division namespace: biological_process def: "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." [ISBN:0198547684] subset: goslim_chembl subset: goslim_generic synonym: "mitosis" EXACT [] is_a: GO:0000280 ! nuclear division is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000280 ! nuclear division intersection_of: part_of GO:0000278 ! mitotic cell cycle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19910" xsd:anyURI created_by: pg creation_date: 2017-03-23T14:44:23Z [Term] id: GO:0140029 name: exocytic process namespace: biological_process def: "The cellular processes that contribute to exocytosis." [Wikipedia:Exocytosis] subset: gocheck_do_not_annotate is_a: GO:0009987 ! cellular process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0006887 ! exocytosis relationship: part_of GO:0006887 ! exocytosis created_by: pg creation_date: 2017-05-15T13:20:45Z [Term] id: GO:0140056 name: organelle localization by membrane tethering namespace: biological_process def: "The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other." [PMID:27875684] subset: goslim_pombe is_a: GO:0022406 ! membrane docking is_a: GO:0051640 ! organelle localization created_by: pg creation_date: 2017-06-27T09:58:51Z [Term] id: GO:0140096 name: catalytic activity, acting on a protein namespace: molecular_function def: "Catalytic activity that acts to modify a protein." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: prokaryote_subset is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_input PR:000000001 ! protein relationship: has_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-14T10:32:59Z [Term] id: GO:0140097 name: catalytic activity, acting on DNA namespace: molecular_function def: "Catalytic activity that acts to modify DNA." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: prokaryote_subset is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid intersection_of: GO:0003824 ! catalytic activity intersection_of: has_input CHEBI:16991 ! deoxyribonucleic acid relationship: has_input CHEBI:16991 ! deoxyribonucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-14T12:03:51Z [Term] id: GO:0140098 name: catalytic activity, acting on RNA namespace: molecular_function def: "Catalytic activity that acts to modify RNA, driven by ATP hydrolysis." [GOC:molecular_function_refactoring, GOC:pdt] subset: goslim_generic subset: prokaryote_subset is_a: GO:0140640 ! catalytic activity, acting on a nucleic acid intersection_of: GO:0003824 ! catalytic activity intersection_of: has_input CHEBI:33697 ! ribonucleic acid relationship: has_input CHEBI:33697 ! ribonucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21612" xsd:anyURI created_by: pg creation_date: 2017-09-14T12:05:21Z [Term] id: GO:0140103 name: catalytic activity, acting on a glycoprotein namespace: molecular_function def: "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein." [GOC:molecular_function_refactoring, GOC:pdt] is_a: GO:0140096 ! catalytic activity, acting on a protein intersection_of: GO:0003824 ! catalytic activity intersection_of: has_input CHEBI:17089 ! glycoprotein relationship: has_input CHEBI:17089 ! glycoprotein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14225" xsd:anyURI created_by: pg creation_date: 2017-09-15T19:27:54Z [Term] id: GO:0140112 name: extracellular vesicle biogenesis namespace: biological_process def: "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content." [PMID:28736435] synonym: "extracellular vesicle assembly" EXACT [] is_a: GO:0044085 ! cellular component biogenesis property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14256" xsd:anyURI created_by: pg creation_date: 2017-10-23T11:53:42Z [Term] id: GO:0140236 name: translation at presynapse namespace: biological_process def: "Translation that occurs at the presynapse." [PMID:27321671] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI created_by: pg creation_date: 2018-07-13T13:00:33Z [Term] id: GO:0140237 name: translation at presynapse, modulating chemical synaptic transmission namespace: biological_process def: "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." [PMID:27321671] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140236 ! translation at presynapse intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0007268 ! chemical synaptic transmission relationship: regulates GO:0007268 ! chemical synaptic transmission property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/216" xsd:anyURI created_by: pg creation_date: 2018-07-13T13:07:23Z [Term] id: GO:0140241 name: translation at synapse namespace: biological_process def: "Translation that occurs at the synapse." [PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006412 ! translation intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:23:12Z [Term] id: GO:0140242 name: translation at postsynapse namespace: biological_process def: "Translation that occurs at the postsynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140241 ! translation at synapse intersection_of: GO:0006412 ! translation intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:26:27Z [Term] id: GO:0140243 name: regulation of translation at synapse namespace: biological_process def: "Any process that regulates translation occurring at the synapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0006417 ! regulation of translation intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0006412 ! translation relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:26Z [Term] id: GO:0140244 name: regulation of translation at presynapse namespace: biological_process def: "Any process that regulates translation occurring at the presynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0006412 ! translation relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:33Z [Term] id: GO:0140245 name: regulation of translation at postsynapse namespace: biological_process def: "Any process that regulates translation occurring at the postsynapse." [PMID:20427644] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140243 ! regulation of translation at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0006412 ! translation relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T09:38:54Z [Term] id: GO:0140246 name: protein catabolic process at synapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0030163 ! protein catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/210" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:12:51Z [Term] id: GO:0140247 name: protein catabolic process at presynapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse." [PMID:27764673] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098793 ! presynapse relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:23:49Z [Term] id: GO:0140249 name: protein catabolic process at postsynapse namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140246 ! protein catabolic process at synapse intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098794 ! postsynapse relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:25:04Z [Term] id: GO:0140250 name: regulation protein catabolic process at synapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse." [PMID:23083742] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0009894 ! regulation of catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: has_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0045202 ! synapse intersection_of: regulates GO:0009056 ! catabolic process relationship: has_input CHEBI:36080 ! protein relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: occurs_in GO:0045202 ! synapse relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:34:56Z [Term] id: GO:0140251 name: regulation protein catabolic process at presynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse." [PMID:27764673] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: has_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098793 ! presynapse intersection_of: regulates GO:0009056 ! catabolic process relationship: occurs_in GO:0098793 ! presynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:35:39Z [Term] id: GO:0140252 name: regulation protein catabolic process at postsynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse." [PMID:17062563] comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. subset: goslim_synapse is_a: GO:0140250 ! regulation protein catabolic process at synapse intersection_of: GO:0065007 ! biological regulation intersection_of: has_input CHEBI:36080 ! protein intersection_of: occurs_in GO:0098794 ! postsynapse intersection_of: regulates GO:0009056 ! catabolic process relationship: occurs_in GO:0098794 ! postsynapse property_value: IAO:0000233 "https://github.com/geneontology/synapse/issues/204" xsd:anyURI created_by: pg creation_date: 2018-07-15T10:35:56Z [Term] id: GO:0140253 name: cell-cell fusion namespace: biological_process def: "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." [Wikipedia:Cell_fusion] synonym: "cell cell fusion" EXACT [] synonym: "cell fusion" BROAD [] is_a: GO:0009987 ! cellular process relationship: has_part GO:0045026 ! plasma membrane fusion property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/15939" xsd:anyURI created_by: pg creation_date: 2018-08-13T18:38:18Z [Term] id: GO:0140318 name: protein transporter activity namespace: molecular_function def: "Directly binding to a specific protein and delivering it to a specific cellular location." [PMID:18706423] comment: Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation. synonym: "protein carrier activity" RELATED [] synonym: "protein transport chaperone" RELATED [] xref: Reactome:R-HSA-9662747 "iRHOM2 transports ADAM17 from ER to the Golgi-network" xref: Reactome:R-HSA-9662818 "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane" is_a: GO:0005215 ! transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input PR:000000001 ! protein relationship: has_primary_input PR:000000001 ! protein property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/17073" xsd:anyURI created_by: pg creation_date: 2019-04-01T10:41:38Z [Term] id: GO:0140352 name: export from cell namespace: biological_process def: "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." [GOC:pg] synonym: "efflux" BROAD [] is_a: GO:0006810 ! transport is_a: GO:0009987 ! cellular process intersection_of: GO:0006810 ! transport intersection_of: has_target_end_location GO:0005576 ! extracellular region intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure relationship: has_target_end_location GO:0005576 ! extracellular region relationship: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: pg creation_date: 2019-05-22T11:20:45Z [Term] id: GO:0140353 name: lipid export from cell namespace: biological_process def: "The directed movement of a lipid from a cell, into the extracellular region." [GOC:pg] synonym: "lipid efflux" BROAD [] is_a: GO:0006869 ! lipid transport is_a: GO:0140352 ! export from cell intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid intersection_of: has_target_end_location GO:0005576 ! extracellular region intersection_of: has_target_start_location GO:0005622 ! intracellular anatomical structure created_by: pg creation_date: 2019-05-22T11:33:07Z [Term] id: GO:0140354 name: lipid import into cell namespace: biological_process def: "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." [GOC:pg] synonym: "lipid uptake" BROAD [] is_a: GO:0006869 ! lipid transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:18059 ! lipid intersection_of: has_target_end_location GO:0005622 ! intracellular anatomical structure intersection_of: has_target_start_location GO:0005576 ! extracellular region relationship: has_target_end_location GO:0005622 ! intracellular anatomical structure relationship: has_target_start_location GO:0005576 ! extracellular region created_by: pg creation_date: 2019-05-22T11:38:15Z [Term] id: GO:0140513 name: nuclear protein-containing complex namespace: cellular_component def: "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." [GOC:pg] subset: gocheck_do_not_annotate synonym: "nuclear complex" EXACT [] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: part_of GO:0005634 ! nucleus relationship: part_of GO:0005634 ! nucleus created_by: pg creation_date: 2020-09-09T05:12:38Z [Term] id: GO:0140572 name: vacuole fission namespace: biological_process def: "The division of a vacuole within a cell to form two or more separate vacuoles." [PMID:19643199] is_a: GO:0048285 ! organelle fission intersection_of: GO:0048285 ! organelle fission intersection_of: results_in_fission_of GO:0005773 ! vacuole relationship: results_in_fission_of GO:0005773 ! vacuole property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/20639" xsd:anyURI created_by: pg creation_date: 2021-01-04T10:17:58Z [Term] id: GO:0140640 name: catalytic activity, acting on a nucleic acid namespace: molecular_function def: "Catalytic activity that acts to modify a nucleic acid." [GOC:pg] is_a: GO:0003824 ! catalytic activity intersection_of: GO:0003824 ! catalytic activity intersection_of: has_input CHEBI:33696 ! nucleic acid relationship: has_input CHEBI:33696 ! nucleic acid property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21402" xsd:anyURI created_by: pg creation_date: 2021-05-11T06:31:07Z [Term] id: GO:0140694 name: non-membrane-bounded organelle assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." [PMID:28225081] synonym: "non-membrane-bounded organelle formation" EXACT [] synonym: "non-membrane-enclosed organelle assembly" EXACT [] synonym: "non-membrane-enclosed organelle formation" EXACT [] is_a: GO:0070925 ! organelle assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0043228 ! non-membrane-bounded organelle relationship: results_in_assembly_of GO:0043228 ! non-membrane-bounded organelle property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/21939" xsd:anyURI created_by: pg creation_date: 2021-08-09T15:30:06Z [Term] id: GO:0140734 name: ammonium excretion namespace: biological_process def: "The elimination of ammonium ions from an excretory cell." [PMID:25740900] synonym: "ammonia excretion" RELATED [] is_a: GO:0007588 ! excretion intersection_of: GO:0007588 ! excretion intersection_of: has_primary_input CHEBI:28938 ! ammonium relationship: has_primary_input CHEBI:28938 ! ammonium property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22368" xsd:anyURI created_by: pg creation_date: 2021-11-24T17:55:51Z [Term] id: GO:0140961 name: cellular detoxification of metal ion namespace: biological_process def: "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion." [PMID:26729300, PMID:33046888, PMID:34442707] synonym: "cellular detoxification of metal cation" EXACT [] is_a: GO:0061687 ! detoxification of inorganic compound is_a: GO:1990748 ! cellular detoxification intersection_of: GO:1990748 ! cellular detoxification intersection_of: has_primary_input CHEBI:25213 ! metal cation relationship: has_primary_input CHEBI:25213 ! metal cation created_by: pg creation_date: 2022-12-07T15:35:18Z [Term] id: GO:0150052 name: regulation of postsynapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse." [GOC:aruk, GOC:bc, PMID:16394100, PMID:16672654, PMID:28185854] subset: goslim_synapse is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099175 ! regulation of postsynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099068 ! postsynapse assembly relationship: regulates GO:0099068 ! postsynapse assembly created_by: bc creation_date: 2018-05-08T16:38:55Z [Term] id: GO:0150063 name: visual system development namespace: biological_process def: "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways." [GOC:aruk, GOC:bc, GOC:krc, PMID:15004427, PMID:20647017, PMID:22632727] synonym: "optic pathway development" RELATED [] synonym: "visual pathway development" RELATED [] is_a: GO:0048880 ! sensory system development created_by: bc creation_date: 2018-07-23T10:31:58Z [Term] id: GO:0150076 name: neuroinflammatory response namespace: biological_process def: "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] synonym: "nerve tissue inflammatory response" EXACT [] synonym: "nervous tissue inflammatory response" EXACT [] synonym: "neural tissue inflammatory response" EXACT [] is_a: GO:0006954 ! inflammatory response created_by: bc creation_date: 2018-07-26T12:25:34Z [Term] id: GO:0150077 name: regulation of neuroinflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:10981966, PMID:11099416, PMID:18164423] is_a: GO:0050727 ! regulation of inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0150076 ! neuroinflammatory response relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: regulates GO:0150076 ! neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:32:18Z [Term] id: GO:0150078 name: positive regulation of neuroinflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc] is_a: GO:0050729 ! positive regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0150076 ! neuroinflammatory response relationship: positively_regulates GO:0150076 ! neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:35:50Z [Term] id: GO:0150079 name: negative regulation of neuroinflammatory response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response." [GOC:aruk, GOC:bc, PMID:11099416, PMID:18164423] is_a: GO:0050728 ! negative regulation of inflammatory response is_a: GO:0150077 ! regulation of neuroinflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0150076 ! neuroinflammatory response relationship: negatively_regulates GO:0150076 ! neuroinflammatory response created_by: bc creation_date: 2018-07-26T12:38:08Z [Term] id: GO:0150098 name: glial cell-neuron signaling namespace: biological_process def: "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum." [GOC:aruk, GOC:bc, PMID:14980203, PMID:16144764, PMID:16547515, PMID:18685038, PMID:27788368, PMID:9459440] synonym: "glia-neuron signaling" EXACT [] synonym: "glia-neuron signalling" EXACT [] synonym: "glia-neurone signaling" EXACT [] synonym: "glia-neurone signalling" EXACT [] synonym: "glial cell- neuron signalling" EXACT [] synonym: "glial cell-neurone signalling" EXACT [] synonym: "glial cell-neurone singaling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000540 ! neuron intersection_of: has_start_location CL:0000125 ! glial cell relationship: has_end_location CL:0000540 ! neuron relationship: has_start_location CL:0000125 ! glial cell created_by: bc creation_date: 2018-12-17T12:28:09Z [Term] id: GO:0150099 name: neuron-glial cell signaling namespace: biological_process def: "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine." [GOC:aruk, GOC:bc, PMID:10195197, PMID:10196584, PMID:10377338, PMID:10493741, PMID:11356870, PMID:11399439, PMID:15252819, PMID:27788368] synonym: "neuron-glia signaling" EXACT [] synonym: "neuron-glia signalling" EXACT [] synonym: "neuron-glial cell signalling" EXACT [] synonym: "neurone-glia signaling" EXACT [] synonym: "neurone-glia signalling" EXACT [] synonym: "neurone-glial cell signaling" EXACT [] synonym: "neurone-glial cell signalling" EXACT [] is_a: GO:0007267 ! cell-cell signaling intersection_of: GO:0007267 ! cell-cell signaling intersection_of: has_end_location CL:0000125 ! glial cell intersection_of: has_start_location CL:0000540 ! neuron relationship: has_end_location CL:0000125 ! glial cell relationship: has_start_location CL:0000540 ! neuron created_by: bc creation_date: 2018-12-17T12:30:12Z [Term] id: GO:0150105 name: protein localization to cell-cell junction namespace: biological_process def: "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:1902414 ! protein localization to cell junction intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005911 ! cell-cell junction relationship: has_target_end_location GO:0005911 ! cell-cell junction created_by: bc creation_date: 2019-06-11T11:00:18Z [Term] id: GO:0150106 name: regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0150105 ! protein localization to cell-cell junction relationship: regulates GO:0150105 ! protein localization to cell-cell junction created_by: bc creation_date: 2019-06-11T11:17:15Z [Term] id: GO:0150107 name: positive regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc, PMID:26706435] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0150105 ! protein localization to cell-cell junction relationship: positively_regulates GO:0150105 ! protein localization to cell-cell junction created_by: bc creation_date: 2019-06-11T11:23:58Z [Term] id: GO:0150111 name: regulation of transepithelial transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of transepithelial transport." [GOC:aruk, PMID:27593915] is_a: GO:0051049 ! regulation of transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070633 ! transepithelial transport relationship: regulates GO:0070633 ! transepithelial transport created_by: bc creation_date: 2019-09-15T07:16:49Z [Term] id: GO:0150119 name: negative regulation of protein localization to cell-cell junction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction." [GOC:aruk, GOC:bc] synonym: "negative regulation of protein localisation to cell-cell junction" EXACT [] is_a: GO:0150106 ! regulation of protein localization to cell-cell junction is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0150105 ! protein localization to cell-cell junction relationship: negatively_regulates GO:0150105 ! protein localization to cell-cell junction created_by: bc creation_date: 2019-11-21T13:53:34Z [Term] id: GO:0150146 name: cell junction disassembly namespace: biological_process def: "The disaggregation of a cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0022411 ! cellular component disassembly is_a: GO:0034330 ! cell junction organization intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0030054 ! cell junction relationship: results_in_disassembly_of GO:0030054 ! cell junction created_by: bc creation_date: 2019-12-08T11:12:13Z [Term] id: GO:0150147 name: cell-cell junction disassembly namespace: biological_process def: "The disaggregation of a cell-cell junction into its constituent components." [GOC:aruk, PMID:25490267] is_a: GO:0045216 ! cell-cell junction organization is_a: GO:0150146 ! cell junction disassembly intersection_of: GO:0150146 ! cell junction disassembly intersection_of: results_in_disassembly_of GO:0005911 ! cell-cell junction relationship: results_in_disassembly_of GO:0005911 ! cell-cell junction created_by: bc creation_date: 2019-12-08T11:16:14Z [Term] id: GO:0160038 name: somatic sensory system development namespace: biological_process def: "The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain." [PMID:25832476, PMID:31399790] synonym: "somatosensory system development" EXACT [] is_a: GO:0048880 ! sensory system development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003942 ! somatosensory system relationship: results_in_development_of UBERON:0003942 ! somatosensory system created_by: rynl creation_date: 2022-07-07T16:49:26Z [Term] id: GO:0160043 name: catecholamine secretion, neurotransmission namespace: biological_process def: "The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter." [PMID:10191060] is_a: GO:0007269 ! neurotransmitter secretion is_a: GO:0050432 ! catecholamine secretion intersection_of: GO:0007269 ! neurotransmitter secretion intersection_of: has_primary_input CHEBI:33567 ! catecholamine property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23804" xsd:anyURI created_by: rynl creation_date: 2022-08-17T00:36:44Z [Term] id: GO:0160048 name: craniofacial suture closure namespace: biological_process def: "The process of fusing together the edges of a craniofacial suture." [PMID:33842480] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0060349 ! bone morphogenesis intersection_of: results_in_fusion_of UBERON:0009198 ! craniofacial suture relationship: results_in_fusion_of UBERON:0009198 ! craniofacial suture property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/23213" xsd:anyURI created_by: rynl creation_date: 2022-08-19T23:18:54Z [Term] id: GO:1900015 name: regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] is_a: GO:0001817 ! regulation of cytokine production intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002534 ! cytokine production involved in inflammatory response relationship: regulates GO:0002534 ! cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:27Z [Term] id: GO:1900016 name: negative regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "down regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] synonym: "down regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] synonym: "negative regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] is_a: GO:0001818 ! negative regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response relationship: negatively_regulates GO:0002534 ! cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:31Z [Term] id: GO:1900017 name: positive regulation of cytokine production involved in inflammatory response namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response." [GOC:TermGenie] synonym: "positive regulation of cytokine production involved in acute inflammatory response" NARROW [GOC:TermGenie] synonym: "up regulation of cytokine production involved in acute inflammatory response" BROAD [GOC:TermGenie] synonym: "up regulation of cytokine production involved in inflammatory response" RELATED [GOC:TermGenie] is_a: GO:0001819 ! positive regulation of cytokine production is_a: GO:1900015 ! regulation of cytokine production involved in inflammatory response intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response relationship: positively_regulates GO:0002534 ! cytokine production involved in inflammatory response created_by: rph creation_date: 2012-01-11T09:34:35Z [Term] id: GO:1900073 name: regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] is_a: GO:0050804 ! modulation of chemical synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007274 ! neuromuscular synaptic transmission relationship: regulates GO:0007274 ! neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:10Z [Term] id: GO:1900074 name: negative regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] synonym: "down regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "down-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "downregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "inhibition of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] is_a: GO:0050805 ! negative regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission relationship: negatively_regulates GO:0007274 ! neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:18Z [Term] id: GO:1900075 name: positive regulation of neuromuscular synaptic transmission namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." [GOC:kmv, GOC:TermGenie] synonym: "activation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "up regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "up-regulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] synonym: "upregulation of neuromuscular synaptic transmission" RELATED [GOC:TermGenie] is_a: GO:0050806 ! positive regulation of synaptic transmission is_a: GO:1900073 ! regulation of neuromuscular synaptic transmission intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007274 ! neuromuscular synaptic transmission relationship: positively_regulates GO:0007274 ! neuromuscular synaptic transmission created_by: kmv creation_date: 2012-01-26T10:14:22Z [Term] id: GO:1900115 name: extracellular regulation of signal transduction namespace: biological_process def: "Any regulation of signal transduction that takes place in the extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0009966 ! regulation of signal transduction intersection_of: occurs_in GO:0005576 ! extracellular region relationship: occurs_in GO:0005576 ! extracellular region created_by: bf creation_date: 2012-02-22T10:21:48Z [Term] id: GO:1900116 name: extracellular negative regulation of signal transduction namespace: biological_process def: "Any negative regulation of signal transduction that takes place in extracellular region." [GOC:signaling, GOC:TermGenie] synonym: "down regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "down-regulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "downregulation of signal transduction in extracellular region" EXACT [GOC:TermGenie] synonym: "extracellular inhibition of signaling pathway" NARROW [GOC:bf] synonym: "inhibition of signal transduction in extracellular region" NARROW [GOC:TermGenie] synonym: "negative regulation of signaling pathway in extracellular region" EXACT [GOC:TermGenie] synonym: "negative regulation of signalling pathway in extracellular region" EXACT [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1900115 ! extracellular regulation of signal transduction intersection_of: GO:0009968 ! negative regulation of signal transduction intersection_of: occurs_in GO:0005576 ! extracellular region created_by: bf creation_date: 2012-02-22T10:27:56Z [Term] id: GO:1900117 name: regulation of execution phase of apoptosis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097194 ! execution phase of apoptosis relationship: regulates GO:0097194 ! execution phase of apoptosis created_by: pr creation_date: 2012-02-22T11:26:20Z [Term] id: GO:1900118 name: negative regulation of execution phase of apoptosis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "down regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "inhibition of execution phase of apoptosis" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097194 ! execution phase of apoptosis relationship: negatively_regulates GO:0097194 ! execution phase of apoptosis created_by: pr creation_date: 2012-02-22T11:26:24Z [Term] id: GO:1900119 name: positive regulation of execution phase of apoptosis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis." [GOC:mtg_apoptosis, GOC:TermGenie] synonym: "activation of execution phase of apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of execution phase of apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of execution phase of apoptosis" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1900117 ! regulation of execution phase of apoptosis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097194 ! execution phase of apoptosis relationship: positively_regulates GO:0097194 ! execution phase of apoptosis created_by: pr creation_date: 2012-02-22T11:26:27Z [Term] id: GO:1900125 name: regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0032885 ! regulation of polysaccharide biosynthetic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030213 ! hyaluronan biosynthetic process relationship: regulates GO:0030213 ! hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:21Z [Term] id: GO:1900126 name: negative regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "down regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "down-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "downregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "inhibition of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "negative regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0045912 ! negative regulation of carbohydrate metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process relationship: negatively_regulates GO:0030213 ! hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:29Z [Term] id: GO:1900127 name: positive regulation of hyaluronan biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process." [GOC:TermGenie, GOC:yaf] synonym: "activation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "activation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "positive regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "up-regulation of hyaluronan synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan formation" EXACT [GOC:TermGenie] synonym: "upregulation of hyaluronan synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0045913 ! positive regulation of carbohydrate metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1900125 ! regulation of hyaluronan biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030213 ! hyaluronan biosynthetic process relationship: positively_regulates GO:0030213 ! hyaluronan biosynthetic process created_by: yaf creation_date: 2012-02-23T01:09:33Z [Term] id: GO:1900141 name: regulation of oligodendrocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] synonym: "regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:0034350 ! regulation of glial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097252 ! oligodendrocyte apoptotic process relationship: regulates GO:0097252 ! oligodendrocyte apoptotic process created_by: yaf creation_date: 2012-03-06T10:22:45Z [Term] id: GO:1900142 name: negative regulation of oligodendrocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] synonym: "down regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of oligodendrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:0034351 ! negative regulation of glial cell apoptotic process is_a: GO:1900141 ! regulation of oligodendrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097252 ! oligodendrocyte apoptotic process relationship: negatively_regulates GO:0097252 ! oligodendrocyte apoptotic process created_by: yaf creation_date: 2012-03-06T10:22:50Z [Term] id: GO:1900143 name: positive regulation of oligodendrocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process." [GOC:TermGenie, GOC:yaf] synonym: "activation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of oligodendrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of oligodendrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of oligodendrocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034352 ! positive regulation of glial cell apoptotic process is_a: GO:1900141 ! regulation of oligodendrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097252 ! oligodendrocyte apoptotic process relationship: positively_regulates GO:0097252 ! oligodendrocyte apoptotic process created_by: yaf creation_date: 2012-03-06T10:22:54Z [Term] id: GO:1900147 name: regulation of Schwann cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0036135 ! Schwann cell migration relationship: regulates GO:0036135 ! Schwann cell migration created_by: bf creation_date: 2012-03-06T04:14:50Z [Term] id: GO:1900148 name: negative regulation of Schwann cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] synonym: "down regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of Schwann cell migration" NARROW [GOC:TermGenie] is_a: GO:1900147 ! regulation of Schwann cell migration is_a: GO:1903976 ! negative regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0036135 ! Schwann cell migration relationship: negatively_regulates GO:0036135 ! Schwann cell migration created_by: bf creation_date: 2012-03-06T04:14:55Z [Term] id: GO:1900149 name: positive regulation of Schwann cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of Schwann cell migration." [GOC:sjw, GOC:TermGenie] synonym: "activation of Schwann cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of Schwann cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of Schwann cell migration" EXACT [GOC:TermGenie] is_a: GO:1900147 ! regulation of Schwann cell migration is_a: GO:1903977 ! positive regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0036135 ! Schwann cell migration relationship: positively_regulates GO:0036135 ! Schwann cell migration created_by: bf creation_date: 2012-03-06T04:14:58Z [Term] id: GO:1900150 name: regulation of defense response to fungus namespace: biological_process alt_id: GO:2000072 def: "Any process that modulates the frequency, rate or extent of defense response to fungus." [GOC:dhl, GOC:TermGenie, PMID:22242006] synonym: "regulation of defence response to fungi" EXACT [GOC:TermGenie] synonym: "regulation of defence response to fungus" EXACT [GOC:TermGenie] synonym: "regulation of defense response to fungi" EXACT [GOC:TermGenie] synonym: "regulation of defense response to fungi, incompatible interaction" NARROW [GOC:obol] synonym: "regulation of defense response to fungus, incompatible interaction" NARROW [] synonym: "regulation of resistance response to pathogenic fungi" NARROW [GOC:obol] synonym: "regulation of resistance response to pathogenic fungus" NARROW [GOC:obol] synonym: "regulation of response to pathogenic fungus (incompatible interaction)" NARROW [GOC:obol] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050832 ! defense response to fungus relationship: regulates GO:0050832 ! defense response to fungus created_by: dhl creation_date: 2012-03-06T10:00:16Z [Term] id: GO:1900180 name: regulation of protein localization to nucleus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034504 ! protein localization to nucleus relationship: regulates GO:0034504 ! protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:44Z [Term] id: GO:1900181 name: negative regulation of protein localization to nucleus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in cell nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in nucleus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to nucleus" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034504 ! protein localization to nucleus relationship: negatively_regulates GO:0034504 ! protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:48Z [Term] id: GO:1900182 name: positive regulation of protein localization to nucleus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." [GOC:TermGenie] synonym: "activation of protein localisation to nucleus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in cell nucleus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "activation of protein localization to nucleus" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034504 ! protein localization to nucleus relationship: positively_regulates GO:0034504 ! protein localization to nucleus created_by: bf creation_date: 2012-03-12T01:23:52Z [Term] id: GO:1900193 name: regulation of oocyte maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001556 ! oocyte maturation relationship: regulates GO:0001556 ! oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:18Z [Term] id: GO:1900194 name: negative regulation of oocyte maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "down regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "inhibition of oocyte maturation" NARROW [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001556 ! oocyte maturation relationship: negatively_regulates GO:0001556 ! oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:27Z [Term] id: GO:1900195 name: positive regulation of oocyte maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oocyte maturation." [GOC:kmv, GOC:TermGenie] synonym: "activation of oocyte maturation" NARROW [GOC:TermGenie] synonym: "up regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:1900193 ! regulation of oocyte maturation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001556 ! oocyte maturation relationship: positively_regulates GO:0001556 ! oocyte maturation created_by: kmv creation_date: 2012-03-19T09:41:35Z [Term] id: GO:1900200 name: mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:0097152 ! mesenchymal cell apoptotic process is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0001656 ! metanephros development relationship: part_of GO:0001656 ! metanephros development created_by: yaf creation_date: 2012-03-21T11:58:05Z [Term] id: GO:1900204 name: apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any apoptotic process that is involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0072205 ! metanephric collecting duct development relationship: part_of GO:0072205 ! metanephric collecting duct development created_by: yaf creation_date: 2012-03-21T01:21:32Z [Term] id: GO:1900205 name: apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any apoptotic process that is involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1902742 ! apoptotic process involved in development intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0072234 ! metanephric nephron tubule development relationship: part_of GO:0072234 ! metanephric nephron tubule development created_by: yaf creation_date: 2012-03-21T01:21:45Z [Term] id: GO:1900206 name: regulation of pronephric nephron tubule development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pronephric nephron tubule development." [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0039020 ! pronephric nephron tubule development relationship: regulates GO:0039020 ! pronephric nephron tubule development created_by: bf creation_date: 2012-03-22T09:23:13Z [Term] id: GO:1900207 name: negative regulation of pronephric nephron tubule development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development." [GOC:bf, GOC:TermGenie, PMID:9758706] synonym: "down regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of pronephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of pronephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1900206 ! regulation of pronephric nephron tubule development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0039020 ! pronephric nephron tubule development relationship: negatively_regulates GO:0039020 ! pronephric nephron tubule development created_by: bf creation_date: 2012-03-22T09:23:23Z [Term] id: GO:1900211 name: regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:1904748 ! regulation of apoptotic process involved in development is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development relationship: regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:52:50Z [Term] id: GO:1900212 name: negative regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "inhibition of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] synonym: "negative regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development is_a: GO:2001054 ! negative regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development relationship: negatively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:53:00Z [Term] id: GO:1900213 name: positive regulation of mesenchymal cell apoptotic process involved in metanephros development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development." [GOC:mtg_apoptosis, GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of mesenchymal cell apoptosis involved in metanephros development" NARROW [GOC:TermGenie] synonym: "positive regulation of mesenchymal cell apoptosis involved in metanephros development" NARROW [] synonym: "up regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal cell apoptosis involved in metanephros development" EXACT [GOC:TermGenie] is_a: GO:1900211 ! regulation of mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development is_a: GO:2001055 ! positive regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development relationship: positively_regulates GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development created_by: yaf creation_date: 2012-03-22T10:53:09Z [Term] id: GO:1900214 name: regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development relationship: regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:21Z [Term] id: GO:1900215 name: negative regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development relationship: negatively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:31Z [Term] id: GO:1900216 name: positive regulation of apoptotic process involved in metanephric collecting duct development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process involved in metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program of metanephric collecting duct development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric collecting duct development" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity of metanephric collecting duct development" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death of metanephric collecting duct development" NARROW [GOC:TermGenie] is_a: GO:1900214 ! regulation of apoptotic process involved in metanephric collecting duct development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development relationship: positively_regulates GO:1900204 ! apoptotic process involved in metanephric collecting duct development created_by: yaf creation_date: 2012-03-22T10:53:39Z [Term] id: GO:1900217 name: regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development relationship: regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:53:51Z [Term] id: GO:1900218 name: negative regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "down regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development relationship: negatively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:54:01Z [Term] id: GO:1900219 name: positive regulation of apoptotic process involved in metanephric nephron tubule development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development." [GOC:mtg_kidney_jan10, GOC:TermGenie, GOC:yaf, PMID:17314325] synonym: "activation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic process involved in metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program of metanephric nephron tubule development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death of metanephric nephron tubule development" NARROW [GOC:TermGenie] is_a: GO:1900217 ! regulation of apoptotic process involved in metanephric nephron tubule development is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development relationship: positively_regulates GO:1900205 ! apoptotic process involved in metanephric nephron tubule development created_by: yaf creation_date: 2012-03-22T10:54:09Z [Term] id: GO:1900366 name: negative regulation of defense response to insect namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "down regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "down-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "downregulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "inhibition of defense response to insect" NARROW [GOC:TermGenie] synonym: "inhibition of physiological defense response to insect" NARROW [GOC:TermGenie] synonym: "negative regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "susceptibility to insect" RELATED [] is_a: GO:0031348 ! negative regulation of defense response is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002213 ! defense response to insect relationship: negatively_regulates GO:0002213 ! defense response to insect created_by: dhl creation_date: 2012-04-12T04:44:00Z [Term] id: GO:1900367 name: positive regulation of defense response to insect namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of defense response to insect." [GOC:TermGenie, PMID:22474183] synonym: "activation of defense response to insect" NARROW [GOC:TermGenie] synonym: "activation of physiological defense response to insect" NARROW [GOC:TermGenie] synonym: "positive regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "up-regulation of physiological defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to insect" EXACT [GOC:TermGenie] synonym: "upregulation of physiological defense response to insect" EXACT [GOC:TermGenie] is_a: GO:0031349 ! positive regulation of defense response is_a: GO:2000068 ! regulation of defense response to insect intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002213 ! defense response to insect relationship: positively_regulates GO:0002213 ! defense response to insect created_by: dhl creation_date: 2012-04-12T04:44:10Z [Term] id: GO:1900376 name: regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0043455 ! regulation of secondary metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044550 ! secondary metabolite biosynthetic process relationship: regulates GO:0044550 ! secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:23Z [Term] id: GO:1900377 name: negative regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "inhibition of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] synonym: "negative regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process relationship: negatively_regulates GO:0044550 ! secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:32Z [Term] id: GO:1900378 name: positive regulation of secondary metabolite biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process." [GOC:di, GOC:TermGenie] synonym: "activation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of secondary metabolite biosynthetic process" NARROW [GOC:TermGenie] synonym: "positive regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of secondary metabolite biosynthetic process" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:1900376 ! regulation of secondary metabolite biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process relationship: positively_regulates GO:0044550 ! secondary metabolite biosynthetic process created_by: di creation_date: 2012-04-17T01:55:41Z [Term] id: GO:1900424 name: regulation of defense response to bacterium namespace: biological_process alt_id: GO:1902477 def: "Any process that modulates the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "regulation of defence response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "regulation of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie] synonym: "regulation of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "regulation of defense response to bacterium, incompatible interaction" NARROW [] synonym: "regulation of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] synonym: "regulation of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] is_a: GO:0002831 ! regulation of response to biotic stimulus is_a: GO:0031347 ! regulation of defense response is_a: GO:0032101 ! regulation of response to external stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042742 ! defense response to bacterium relationship: regulates GO:0042742 ! defense response to bacterium created_by: dhl creation_date: 2012-04-24T10:12:43Z [Term] id: GO:1900425 name: negative regulation of defense response to bacterium namespace: biological_process alt_id: GO:1902478 def: "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "down regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "down regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "down regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "down regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "down regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "down-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "down-regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "down-regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "down-regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "downregulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "downregulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "downregulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "downregulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "inhibition of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "inhibition of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "inhibition of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "inhibition of defence response to pathogenic bacteria, incompatible interaction" NARROW [GOC:TermGenie] synonym: "inhibition of defence response to pathogenic bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "inhibition of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "inhibition of defense response to bacterium" NARROW [GOC:TermGenie] synonym: "inhibition of defense response to bacterium, incompatible interaction" NARROW [GOC:TermGenie] synonym: "inhibition of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] synonym: "inhibition of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] synonym: "inhibition of response to pathogenic bacteria (incompatible interaction)" NARROW [GOC:TermGenie] synonym: "inhibition of response to pathogenic bacterium (incompatible interaction)" NARROW [GOC:TermGenie] synonym: "negative regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "negative regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "negative regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "negative regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "negative regulation of defense response to bacterium, incompatible interaction" NARROW [] is_a: GO:0002832 ! negative regulation of response to biotic stimulus is_a: GO:0031348 ! negative regulation of defense response is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:1900424 ! regulation of defense response to bacterium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042742 ! defense response to bacterium relationship: negatively_regulates GO:0042742 ! defense response to bacterium created_by: dhl creation_date: 2012-04-24T10:12:54Z [Term] id: GO:1900426 name: positive regulation of defense response to bacterium namespace: biological_process alt_id: GO:1902479 def: "Any process that activates or increases the frequency, rate or extent of defense response to bacterium." [GOC:TermGenie, PMID:22346749] synonym: "activation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "activation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "activation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "activation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "activation of defense response to bacterium" NARROW [GOC:TermGenie] synonym: "activation of resistance response to pathogenic bacteria" NARROW [GOC:TermGenie] synonym: "activation of resistance response to pathogenic bacterium" NARROW [GOC:TermGenie] synonym: "positive regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "positive regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "positive regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "positive regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "positive regulation of defense response to bacterium, incompatible interaction" NARROW [] synonym: "up regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "up regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "up regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "up regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "up-regulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "up-regulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "up-regulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "up-regulation of defense response to bacterium" EXACT [GOC:TermGenie] synonym: "upregulation of antibacterial peptide activity" RELATED [GOC:TermGenie] synonym: "upregulation of defence response to bacteria" EXACT [GOC:TermGenie] synonym: "upregulation of defence response to bacterium" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to bacteria" EXACT [GOC:TermGenie] synonym: "upregulation of defense response to bacterium" EXACT [GOC:TermGenie] is_a: GO:0002833 ! positive regulation of response to biotic stimulus is_a: GO:0031349 ! positive regulation of defense response is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:1900424 ! regulation of defense response to bacterium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042742 ! defense response to bacterium relationship: positively_regulates GO:0042742 ! defense response to bacterium created_by: dhl creation_date: 2012-04-24T10:13:13Z [Term] id: GO:1900619 name: acetate ester metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie] synonym: "acetate ester metabolism" EXACT [GOC:TermGenie] synonym: "acetyl ester metabolic process" EXACT [CHEBI:47622] synonym: "acetyl ester metabolism" EXACT [CHEBI:47622] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:47622 ! acetate ester relationship: has_primary_input_or_output CHEBI:47622 ! acetate ester created_by: bf creation_date: 2012-05-16T12:29:51Z [Term] id: GO:1900620 name: acetate ester biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." [GOC:TermGenie, PMID:15042596] synonym: "acetate ester anabolism" EXACT [GOC:TermGenie] synonym: "acetate ester biosynthesis" EXACT [GOC:TermGenie] synonym: "acetate ester formation" EXACT [GOC:TermGenie] synonym: "acetate ester synthesis" EXACT [GOC:TermGenie] synonym: "acetyl ester biosynthesis" EXACT [CHEBI:47622] synonym: "acetyl ester biosynthetic process" EXACT [CHEBI:47622] is_a: GO:1900619 ! acetate ester metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:47622 ! acetate ester relationship: has_primary_output CHEBI:47622 ! acetate ester created_by: bf creation_date: 2012-05-16T12:30:12Z [Term] id: GO:1901135 name: carbohydrate derivative metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carbohydrate derivative." [GOC:TermGenie] subset: goslim_agr subset: goslim_generic subset: goslim_mouse subset: prokaryote_subset synonym: "carbohydrate derivative metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input_or_output CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:09Z [Term] id: GO:1901136 name: carbohydrate derivative catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative breakdown" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative catabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative degradation" EXACT [GOC:TermGenie] is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:31Z [Term] id: GO:1901137 name: carbohydrate derivative biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of carbohydrate derivative." [GOC:TermGenie] synonym: "carbohydrate derivative anabolism" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative biosynthesis" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative formation" EXACT [GOC:TermGenie] synonym: "carbohydrate derivative synthesis" EXACT [GOC:TermGenie] is_a: GO:1901135 ! carbohydrate derivative metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:63299 ! carbohydrate derivative relationship: has_primary_output CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-07-12T04:05:39Z [Term] id: GO:1901142 name: insulin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving insulin." [GOC:TermGenie] synonym: "insulin metabolism" EXACT [GOC:TermGenie] is_a: GO:0019538 ! protein metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output PR:000009054 ! insulin gene translation product relationship: has_primary_input_or_output PR:000009054 ! insulin gene translation product property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon_Union:0000023 created_by: pm creation_date: 2012-07-13T12:32:40Z [Term] id: GO:1901143 name: insulin catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of insulin." [GOC:TermGenie] synonym: "insulin breakdown" EXACT [GOC:TermGenie] synonym: "insulin catabolism" EXACT [GOC:TermGenie] synonym: "insulin degradation" EXACT [GOC:TermGenie] is_a: GO:0030163 ! protein catabolic process is_a: GO:1901142 ! insulin metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input PR:000009054 ! insulin gene translation product relationship: has_primary_input PR:000009054 ! insulin gene translation product created_by: pm creation_date: 2012-07-13T12:33:03Z [Term] id: GO:1901145 name: mesenchymal cell apoptotic process involved in nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis is_a: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0072028 ! nephron morphogenesis relationship: part_of GO:0072028 ! nephron morphogenesis created_by: pr creation_date: 2012-07-13T01:43:51Z [Term] id: GO:1901146 name: mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0061228 ! mesonephric nephron morphogenesis relationship: part_of GO:0061228 ! mesonephric nephron morphogenesis created_by: pr creation_date: 2012-07-13T02:40:43Z [Term] id: GO:1901147 name: mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis namespace: biological_process def: "Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis." [GOC:mtg_apoptosis, GOC:TermGenie] is_a: GO:1900200 ! mesenchymal cell apoptotic process involved in metanephros development is_a: GO:1901145 ! mesenchymal cell apoptotic process involved in nephron morphogenesis intersection_of: GO:0097152 ! mesenchymal cell apoptotic process intersection_of: part_of GO:0072273 ! metanephric nephron morphogenesis relationship: part_of GO:0072273 ! metanephric nephron morphogenesis created_by: pr creation_date: 2012-07-13T02:41:12Z [Term] id: GO:1901148 name: gene expression involved in extracellular matrix organization namespace: biological_process def: "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form." [GOC:pg, GOC:TermGenie, PMID:18668558] synonym: "expression of extracellular matrix proteins" EXACT [GOC:bf] synonym: "extracellular matrix protein production" RELATED [GOC:pg] is_a: GO:0010467 ! gene expression intersection_of: GO:0010467 ! gene expression intersection_of: part_of GO:0030198 ! extracellular matrix organization relationship: part_of GO:0030198 ! extracellular matrix organization created_by: bf creation_date: 2012-07-16T03:29:30Z [Term] id: GO:1901160 name: primary amino compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving primary amino compound." [GOC:TermGenie] synonym: "primary amino compound metabolism" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:50994 ! primary amino compound relationship: has_primary_input_or_output CHEBI:50994 ! primary amino compound created_by: bf creation_date: 2012-07-18T04:44:39Z [Term] id: GO:1901161 name: primary amino compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound breakdown" EXACT [GOC:TermGenie] synonym: "primary amino compound catabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901160 ! primary amino compound metabolic process is_a: GO:1901565 ! organonitrogen compound catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:50994 ! primary amino compound relationship: has_primary_input CHEBI:50994 ! primary amino compound created_by: bf creation_date: 2012-07-18T04:45:06Z [Term] id: GO:1901162 name: primary amino compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of primary amino compound." [GOC:TermGenie] synonym: "primary amino compound anabolism" EXACT [GOC:TermGenie] synonym: "primary amino compound biosynthesis" EXACT [GOC:TermGenie] synonym: "primary amino compound formation" EXACT [GOC:TermGenie] synonym: "primary amino compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901160 ! primary amino compound metabolic process is_a: GO:1901566 ! organonitrogen compound biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:50994 ! primary amino compound relationship: has_primary_output CHEBI:50994 ! primary amino compound created_by: bf creation_date: 2012-07-18T04:45:14Z [Term] id: GO:1901163 name: regulation of trophoblast cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061450 ! trophoblast cell migration relationship: regulates GO:0061450 ! trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:06Z [Term] id: GO:1901164 name: negative regulation of trophoblast cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of trophoblast cell migration" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061450 ! trophoblast cell migration relationship: negatively_regulates GO:0061450 ! trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:28Z [Term] id: GO:1901165 name: positive regulation of trophoblast cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration." [GOC:BHF, GOC:TermGenie] synonym: "activation of trophoblast cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of trophoblast cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of trophoblast cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901163 ! regulation of trophoblast cell migration is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061450 ! trophoblast cell migration relationship: positively_regulates GO:0061450 ! trophoblast cell migration created_by: vk creation_date: 2012-07-19T07:53:35Z [Term] id: GO:1901166 name: neural crest cell migration involved in autonomic nervous system development namespace: biological_process def: "Any neural crest cell migration that is involved in autonomic nervous system development." [GOC:BHF, GOC:TermGenie] is_a: GO:0001755 ! neural crest cell migration intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0048483 ! autonomic nervous system development relationship: part_of GO:0048483 ! autonomic nervous system development created_by: vk creation_date: 2012-07-19T08:39:56Z [Term] id: GO:1901190 name: regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0043254 ! regulation of protein-containing complex assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001677 ! formation of translation initiation ternary complex relationship: regulates GO:0001677 ! formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:26:58Z [Term] id: GO:1901191 name: negative regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "down regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "down-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "downregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "downregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "inhibition of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] synonym: "inhibition of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "negative regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031333 ! negative regulation of protein-containing complex assembly is_a: GO:0045947 ! negative regulation of translational initiation is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex relationship: negatively_regulates GO:0001677 ! formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:27:21Z [Term] id: GO:1901192 name: positive regulation of formation of translation initiation ternary complex namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex." [GOC:TermGenie] synonym: "activation of formation of translation initiation ternary complex" NARROW [GOC:TermGenie] synonym: "activation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "positive regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "up-regulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] synonym: "upregulation of formation of translation initiation ternary complex" EXACT [GOC:TermGenie] synonym: "upregulation of translation initiation ternary complex assembly" EXACT [GOC:TermGenie] is_a: GO:0031334 ! positive regulation of protein-containing complex assembly is_a: GO:1901190 ! regulation of formation of translation initiation ternary complex intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001677 ! formation of translation initiation ternary complex relationship: positively_regulates GO:0001677 ! formation of translation initiation ternary complex created_by: ss creation_date: 2012-07-25T02:27:29Z [Term] id: GO:1901201 name: regulation of extracellular matrix assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0085029 ! extracellular matrix assembly relationship: regulates GO:0085029 ! extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:00Z [Term] id: GO:1901202 name: negative regulation of extracellular matrix assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "inhibition of extracellular matrix assembly" NARROW [GOC:TermGenie] is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903054 ! negative regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0085029 ! extracellular matrix assembly relationship: negatively_regulates GO:0085029 ! extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:24Z [Term] id: GO:1901203 name: positive regulation of extracellular matrix assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly." [GOC:BHF, GOC:TermGenie] synonym: "activation of extracellular matrix assembly" NARROW [GOC:TermGenie] synonym: "up regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1901201 ! regulation of extracellular matrix assembly is_a: GO:1903055 ! positive regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0085029 ! extracellular matrix assembly relationship: positively_regulates GO:0085029 ! extracellular matrix assembly created_by: rl creation_date: 2012-07-27T04:04:32Z [Term] id: GO:1901210 name: regulation of cardiac chamber formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003207 ! cardiac chamber formation relationship: regulates GO:0003207 ! cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:18:35Z [Term] id: GO:1901211 name: negative regulation of cardiac chamber formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac chamber formation" NARROW [GOC:TermGenie] synonym: "inhibition of heart chamber formation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003207 ! cardiac chamber formation relationship: negatively_regulates GO:0003207 ! cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:18:57Z [Term] id: GO:1901212 name: positive regulation of cardiac chamber formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation." [GOC:BHF, GOC:TermGenie] synonym: "activation of cardiac chamber formation" NARROW [GOC:TermGenie] synonym: "activation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber formation" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber formation" EXACT [GOC:TermGenie] is_a: GO:1901210 ! regulation of cardiac chamber formation is_a: GO:1901221 ! positive regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003207 ! cardiac chamber formation relationship: positively_regulates GO:0003207 ! cardiac chamber formation created_by: rl creation_date: 2012-07-31T07:19:05Z [Term] id: GO:1901214 name: regulation of neuron death namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron death." [GOC:rph, GOC:TermGenie] synonym: "regulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "regulation of neuronal cell death" EXACT [GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070997 ! neuron death relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: regulates GO:0070997 ! neuron death created_by: rph creation_date: 2012-08-02T09:57:41Z [Term] id: GO:1901215 name: negative regulation of neuron death namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron death." [GOC:rph, GOC:TermGenie] synonym: "down regulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "down regulation of neuron death" EXACT [GOC:TermGenie] synonym: "down regulation of neuronal cell death" EXACT [GOC:TermGenie] synonym: "down-regulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "down-regulation of neuron death" EXACT [GOC:TermGenie] synonym: "down-regulation of neuronal cell death" EXACT [GOC:TermGenie] synonym: "downregulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "downregulation of neuron death" EXACT [GOC:TermGenie] synonym: "downregulation of neuronal cell death" EXACT [GOC:TermGenie] synonym: "inhibition of neuron cell death" NARROW [GOC:TermGenie] synonym: "inhibition of neuron death" NARROW [GOC:TermGenie] synonym: "inhibition of neuronal cell death" NARROW [GOC:TermGenie] synonym: "negative regulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "negative regulation of neuronal cell death" EXACT [GOC:TermGenie] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:1901214 ! regulation of neuron death intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070997 ! neuron death relationship: negatively_regulates GO:0070997 ! neuron death created_by: rph creation_date: 2012-08-02T09:58:07Z [Term] id: GO:1901216 name: positive regulation of neuron death namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron death." [GOC:rph, GOC:TermGenie] synonym: "activation of neuron cell death" NARROW [GOC:TermGenie] synonym: "activation of neuron death" NARROW [GOC:TermGenie] synonym: "activation of neuronal cell death" NARROW [GOC:TermGenie] synonym: "positive regulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "positive regulation of neuronal cell death" EXACT [GOC:TermGenie] synonym: "up regulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "up regulation of neuron death" EXACT [GOC:TermGenie] synonym: "up regulation of neuronal cell death" EXACT [GOC:TermGenie] synonym: "up-regulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "up-regulation of neuron death" EXACT [GOC:TermGenie] synonym: "up-regulation of neuronal cell death" EXACT [GOC:TermGenie] synonym: "upregulation of neuron cell death" EXACT [GOC:TermGenie] synonym: "upregulation of neuron death" EXACT [GOC:TermGenie] synonym: "upregulation of neuronal cell death" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:1901214 ! regulation of neuron death intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070997 ! neuron death relationship: positively_regulates GO:0070997 ! neuron death created_by: rph creation_date: 2012-08-02T09:58:15Z [Term] id: GO:1901219 name: regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:2000826 ! regulation of heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003206 ! cardiac chamber morphogenesis relationship: regulates GO:0003206 ! cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:11Z [Term] id: GO:1901220 name: negative regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of heart chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis relationship: negatively_regulates GO:0003206 ! cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:34Z [Term] id: GO:1901221 name: positive regulation of cardiac chamber morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis." [GOC:BHF, GOC:TermGenie] synonym: "activation of cardiac chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of heart chamber morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac chamber morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of heart chamber morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901219 ! regulation of cardiac chamber morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003206 ! cardiac chamber morphogenesis relationship: positively_regulates GO:0003206 ! cardiac chamber morphogenesis created_by: rl creation_date: 2012-08-06T17:59:42Z [Term] id: GO:1901246 name: regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061141 ! lung ciliated cell differentiation relationship: regulates GO:0061141 ! lung ciliated cell differentiation created_by: vk creation_date: 2012-08-08T08:58:34Z [Term] id: GO:1901247 name: negative regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of lung ciliated cell differentiation" NARROW [GOC:TermGenie] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901246 ! regulation of lung ciliated cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061141 ! lung ciliated cell differentiation relationship: negatively_regulates GO:0061141 ! lung ciliated cell differentiation created_by: vk creation_date: 2012-08-08T08:58:58Z [Term] id: GO:1901248 name: positive regulation of lung ciliated cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation." [GOC:BHF, GOC:TermGenie] synonym: "activation of lung ciliated cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of lung ciliated cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901246 ! regulation of lung ciliated cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061141 ! lung ciliated cell differentiation relationship: positively_regulates GO:0061141 ! lung ciliated cell differentiation created_by: vk creation_date: 2012-08-08T08:59:05Z [Term] id: GO:1901264 name: carbohydrate derivative transport namespace: biological_process def: "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:bf, GOC:jl, GOC:TermGenie] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative created_by: bf creation_date: 2012-08-16T14:51:22Z [Term] id: GO:1901317 name: regulation of flagellated sperm motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] synonym: "regulation of sperm motility" BROAD [] synonym: "regulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0060295 ! regulation of cilium movement involved in cell motility is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030317 ! flagellated sperm motility relationship: regulates GO:0030317 ! flagellated sperm motility created_by: hjd creation_date: 2012-08-22T20:50:14Z [Term] id: GO:1901318 name: negative regulation of flagellated sperm motility namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:krc, GOC:TermGenie] synonym: "down regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "down regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "down-regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "down-regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "downregulation of sperm motility" BROAD [GOC:TermGenie] synonym: "downregulation of sperm movement" BROAD [GOC:TermGenie] synonym: "inhibition of sperm motility" NARROW [GOC:TermGenie] synonym: "inhibition of sperm movement" BROAD [GOC:TermGenie] synonym: "negative regulation of sperm motility" BROAD [] synonym: "negative regulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0003354 ! negative regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:1902020 ! negative regulation of cilium-dependent cell motility is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030317 ! flagellated sperm motility relationship: negatively_regulates GO:0030317 ! flagellated sperm motility created_by: hjd creation_date: 2012-08-22T20:50:35Z [Term] id: GO:1901329 name: regulation of odontoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071895 ! odontoblast differentiation relationship: regulates GO:0071895 ! odontoblast differentiation created_by: hjd creation_date: 2012-08-31T16:50:05Z [Term] id: GO:1901330 name: negative regulation of odontoblast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] synonym: "down regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of odontoblast differentiation" NARROW [GOC:TermGenie] is_a: GO:0002085 ! inhibition of neuroepithelial cell differentiation is_a: GO:1901329 ! regulation of odontoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071895 ! odontoblast differentiation relationship: negatively_regulates GO:0071895 ! odontoblast differentiation created_by: hjd creation_date: 2012-08-31T16:50:27Z [Term] id: GO:1901331 name: positive regulation of odontoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of odontoblast differentiation." [GOC:TermGenie] synonym: "activation of odontoblast differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of odontoblast differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of odontoblast differentiation" EXACT [GOC:TermGenie] is_a: GO:1901329 ! regulation of odontoblast differentiation is_a: GO:1902913 ! positive regulation of neuroepithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071895 ! odontoblast differentiation relationship: positively_regulates GO:0071895 ! odontoblast differentiation created_by: hjd creation_date: 2012-08-31T16:50:35Z [Term] id: GO:1901342 name: regulation of vasculature development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vasculature development." [GOC:TermGenie] synonym: "regulation of vascular system development" RELATED [GOC:TermGenie] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001944 ! vasculature development relationship: regulates GO:0001944 ! vasculature development created_by: bf creation_date: 2012-09-06T09:16:15Z [Term] id: GO:1901343 name: negative regulation of vasculature development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development." [GOC:TermGenie] synonym: "down regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "down regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "down-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "downregulation of vascular system development" RELATED [GOC:TermGenie] synonym: "downregulation of vasculature development" EXACT [GOC:TermGenie] synonym: "inhibition of vascular system development" RELATED [GOC:TermGenie] synonym: "inhibition of vasculature development" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular system development" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001944 ! vasculature development relationship: negatively_regulates GO:0001944 ! vasculature development created_by: bf creation_date: 2012-09-06T09:17:24Z [Term] id: GO:1901360 name: organic cyclic compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound relationship: has_primary_input_or_output CHEBI:33832 ! organic cyclic compound created_by: bf creation_date: 2012-09-14T09:03:51Z [Term] id: GO:1901361 name: organic cyclic compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound breakdown" EXACT [GOC:TermGenie] synonym: "organic cyclic compound catabolism" EXACT [GOC:TermGenie] synonym: "organic cyclic compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33832 ! organic cyclic compound relationship: has_primary_input CHEBI:33832 ! organic cyclic compound created_by: bf creation_date: 2012-09-14T09:05:04Z [Term] id: GO:1901362 name: organic cyclic compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic cyclic compound." [GOC:TermGenie] synonym: "organic cyclic compound anabolism" EXACT [GOC:TermGenie] synonym: "organic cyclic compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organic cyclic compound formation" EXACT [GOC:TermGenie] synonym: "organic cyclic compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901360 ! organic cyclic compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33832 ! organic cyclic compound relationship: has_primary_output CHEBI:33832 ! organic cyclic compound created_by: bf creation_date: 2012-09-14T09:05:22Z [Term] id: GO:1901374 name: acetate ester transport namespace: biological_process def: "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." [GOC:TermGenie] is_a: GO:0071702 ! organic substance transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:47622 ! acetate ester relationship: has_primary_input CHEBI:47622 ! acetate ester created_by: bf creation_date: 2012-09-28T10:42:13Z [Term] id: GO:1901375 name: acetate ester transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of an acetate ester from one side of a membrane to the other." [GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:47622 ! acetate ester relationship: has_primary_input CHEBI:47622 ! acetate ester relationship: part_of GO:1901374 ! acetate ester transport created_by: bf creation_date: 2012-09-28T10:47:08Z [Term] id: GO:1901382 name: regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097360 ! chorionic trophoblast cell proliferation relationship: regulates GO:0097360 ! chorionic trophoblast cell proliferation created_by: vk creation_date: 2012-10-01T10:03:13Z [Term] id: GO:1901383 name: negative regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "down regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation relationship: negatively_regulates GO:0097360 ! chorionic trophoblast cell proliferation created_by: vk creation_date: 2012-10-01T10:04:23Z [Term] id: GO:1901384 name: positive regulation of chorionic trophoblast cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation." [GOC:BHF, GOC:TermGenie] synonym: "activation of chorionic trophoblast cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of chorionic trophoblast cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901382 ! regulation of chorionic trophoblast cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation relationship: positively_regulates GO:0097360 ! chorionic trophoblast cell proliferation created_by: vk creation_date: 2012-10-01T10:04:41Z [Term] id: GO:1901401 name: regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033013 ! tetrapyrrole metabolic process relationship: regulates GO:0033013 ! tetrapyrrole metabolic process created_by: tt creation_date: 2012-10-01T14:34:03Z [Term] id: GO:1901402 name: negative regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process relationship: negatively_regulates GO:0033013 ! tetrapyrrole metabolic process created_by: tt creation_date: 2012-10-01T14:35:11Z [Term] id: GO:1901403 name: positive regulation of tetrapyrrole metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole metabolic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole metabolism" EXACT [GOC:TermGenie] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033013 ! tetrapyrrole metabolic process relationship: positively_regulates GO:0033013 ! tetrapyrrole metabolic process created_by: tt creation_date: 2012-10-01T14:35:29Z [Term] id: GO:1901404 name: regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031329 ! regulation of cellular catabolic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033015 ! tetrapyrrole catabolic process relationship: regulates GO:0033015 ! tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:38:12Z [Term] id: GO:1901405 name: negative regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process relationship: negatively_regulates GO:0033015 ! tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:39:22Z [Term] id: GO:1901406 name: positive regulation of tetrapyrrole catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole catabolic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole degradation" EXACT [GOC:TermGenie] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process is_a: GO:1901404 ! regulation of tetrapyrrole catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033015 ! tetrapyrrole catabolic process relationship: positively_regulates GO:0033015 ! tetrapyrrole catabolic process created_by: tt creation_date: 2012-10-01T14:39:40Z [Term] id: GO:1901457 name: regulation of response to acetate namespace: biological_process def: "Any process that modulates the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] is_a: GO:0048583 ! regulation of response to stimulus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010034 ! response to acetate relationship: regulates GO:0010034 ! response to acetate created_by: tt creation_date: 2012-10-02T14:25:06Z [Term] id: GO:1901458 name: negative regulation of response to acetate namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "down-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "downregulation of response to acetate" EXACT [GOC:TermGenie] synonym: "inhibition of response to acetate" NARROW [GOC:TermGenie] is_a: GO:0048585 ! negative regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010034 ! response to acetate relationship: negatively_regulates GO:0010034 ! response to acetate created_by: tt creation_date: 2012-10-02T14:26:15Z [Term] id: GO:1901459 name: positive regulation of response to acetate namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of response to acetate." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of response to acetate" NARROW [GOC:TermGenie] synonym: "up regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "up-regulation of response to acetate" EXACT [GOC:TermGenie] synonym: "upregulation of response to acetate" EXACT [GOC:TermGenie] is_a: GO:0048584 ! positive regulation of response to stimulus is_a: GO:1901457 ! regulation of response to acetate intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010034 ! response to acetate relationship: positively_regulates GO:0010034 ! response to acetate created_by: tt creation_date: 2012-10-02T14:26:34Z [Term] id: GO:1901463 name: regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:1901401 ! regulation of tetrapyrrole metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033014 ! tetrapyrrole biosynthetic process relationship: regulates GO:0033014 ! tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:34:14Z [Term] id: GO:1901464 name: negative regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "down regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "down-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "downregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "inhibition of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "negative regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:1901402 ! negative regulation of tetrapyrrole metabolic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process relationship: negatively_regulates GO:0033014 ! tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:35:26Z [Term] id: GO:1901465 name: positive regulation of tetrapyrrole biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process." [GOC:mengo_curators, GOC:TermGenie] synonym: "activation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "activation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "positive regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "up-regulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole formation" EXACT [GOC:TermGenie] synonym: "upregulation of tetrapyrrole synthesis" EXACT [GOC:TermGenie] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:1901403 ! positive regulation of tetrapyrrole metabolic process is_a: GO:1901463 ! regulation of tetrapyrrole biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process relationship: positively_regulates GO:0033014 ! tetrapyrrole biosynthetic process created_by: tt creation_date: 2012-10-02T14:35:43Z [Term] id: GO:1901505 name: carbohydrate derivative transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of carbohydrate derivative from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] synonym: "carbohydrate derivative transporter activity" RELATED [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: has_primary_input CHEBI:63299 ! carbohydrate derivative relationship: part_of GO:1901264 {http://purl.org/dc/terms/source="GO_REF:0000090"} ! carbohydrate derivative transport created_by: pr creation_date: 2012-10-17T10:31:22Z [Term] id: GO:1901509 name: regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis." [GOC:dph, GOC:TermGenie] is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061154 ! endothelial tube morphogenesis relationship: regulates GO:0061154 ! endothelial tube morphogenesis created_by: dph creation_date: 2012-10-17T14:30:40Z [Term] id: GO:1901532 name: regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002244 ! hematopoietic progenitor cell differentiation relationship: regulates GO:0002244 ! hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:01Z [Term] id: GO:1901533 name: negative regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "down regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "down regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "down-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "downregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "inhibition of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic progenitor cell differentiation" EXACT [] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation relationship: negatively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:06Z [Term] id: GO:1901534 name: positive regulation of hematopoietic progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation." [GOC:BHF, GOC:rl, GOC:TermGenie] synonym: "activation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "activation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "activation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "activation of hemopoietic progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic progenitor cell differentiation" EXACT [] synonym: "up regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "up regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "up-regulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic progenitor cell differentiation" RELATED [GOC:TermGenie] synonym: "upregulation of hemopoietic progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation relationship: positively_regulates GO:0002244 ! hematopoietic progenitor cell differentiation created_by: vk creation_date: 2012-10-24T11:23:14Z [Term] id: GO:1901550 name: regulation of endothelial cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] is_a: GO:0045601 ! regulation of endothelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001885 ! endothelial cell development relationship: regulates GO:0001885 ! endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:50Z [Term] id: GO:1901551 name: negative regulation of endothelial cell development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "down regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial cell development" NARROW [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0045602 ! negative regulation of endothelial cell differentiation is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001885 ! endothelial cell development relationship: negatively_regulates GO:0001885 ! endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:54Z [Term] id: GO:1901552 name: positive regulation of endothelial cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell development." [GOC:pr, GOC:TermGenie, PMID:19470579] synonym: "activation of endothelial cell development" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1901550 ! regulation of endothelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001885 ! endothelial cell development relationship: positively_regulates GO:0001885 ! endothelial cell development created_by: pr creation_date: 2012-10-30T12:59:58Z [Term] id: GO:1901564 name: organonitrogen compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0006807 ! nitrogen compound metabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound relationship: has_primary_input_or_output CHEBI:35352 ! organonitrogen compound created_by: pr creation_date: 2012-11-04T15:17:52Z [Term] id: GO:1901565 name: organonitrogen compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound breakdown" EXACT [GOC:TermGenie] synonym: "organonitrogen compound catabolism" EXACT [GOC:TermGenie] synonym: "organonitrogen compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process is_a: GO:1901575 ! organic substance catabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:35352 ! organonitrogen compound relationship: has_primary_input CHEBI:35352 ! organonitrogen compound created_by: pr creation_date: 2012-11-04T15:17:56Z [Term] id: GO:1901566 name: organonitrogen compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organonitrogen compound." [GOC:pr, GOC:TermGenie] synonym: "organonitrogen compound anabolism" EXACT [GOC:TermGenie] synonym: "organonitrogen compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organonitrogen compound formation" EXACT [GOC:TermGenie] synonym: "organonitrogen compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901564 ! organonitrogen compound metabolic process is_a: GO:1901576 ! organic substance biosynthetic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:35352 ! organonitrogen compound relationship: has_primary_output CHEBI:35352 ! organonitrogen compound created_by: pr creation_date: 2012-11-04T15:18:00Z [Term] id: GO:1901575 name: organic substance catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] synonym: "organic molecular entity breakdown" EXACT [GOC:TermGenie] synonym: "organic molecular entity catabolic process" EXACT [] synonym: "organic molecular entity catabolism" EXACT [GOC:TermGenie] synonym: "organic molecular entity degradation" EXACT [GOC:TermGenie] synonym: "organic substance breakdown" EXACT [] synonym: "organic substance catabolism" EXACT [] synonym: "organic substance degradation" EXACT [] is_a: GO:0009056 ! catabolic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:50860 ! organic molecular entity relationship: has_primary_input CHEBI:50860 ! organic molecular entity created_by: pr creation_date: 2012-11-05T11:04:36Z [Term] id: GO:1901576 name: organic substance biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." [GOC:pr, GOC:TermGenie] synonym: "organic molecular entity anabolism" EXACT [GOC:TermGenie] synonym: "organic molecular entity biosynthesis" EXACT [GOC:TermGenie] synonym: "organic molecular entity biosynthetic process" EXACT [] synonym: "organic molecular entity formation" EXACT [GOC:TermGenie] synonym: "organic molecular entity synthesis" EXACT [GOC:TermGenie] synonym: "organic substance anabolism" EXACT [] synonym: "organic substance biosynthesis" EXACT [] synonym: "organic substance formation" EXACT [] synonym: "organic substance synthesis" EXACT [] is_a: GO:0009058 ! biosynthetic process is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:50860 ! organic molecular entity relationship: has_primary_output CHEBI:50860 ! organic molecular entity created_by: pr creation_date: 2012-11-05T11:04:40Z [Term] id: GO:1901589 name: axon microtubule bundle namespace: cellular_component def: "An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment." [GOC:TermGenie, NIF_Subcellular:sao707332678] synonym: "axon microtubule fascicle" EXACT [] synonym: "microtubule bundle of axon" EXACT [GOC:TermGenie] synonym: "microtubule fascicle of axon" EXACT [GOC:TermGenie] xref: NIF_Subcellular:sao707332678 is_a: GO:0097427 ! microtubule bundle intersection_of: GO:0097427 ! microtubule bundle intersection_of: part_of GO:0030424 ! axon relationship: part_of GO:0030424 ! axon created_by: pr creation_date: 2012-11-07T15:37:12Z [Term] id: GO:1901605 name: alpha-amino acid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0006520 ! amino acid metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion relationship: has_primary_input_or_output CHEBI:78608 ! alpha-amino acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:50Z [Term] id: GO:1901606 name: alpha-amino acid catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid breakdown" EXACT [GOC:TermGenie] synonym: "alpha-amino acid catabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid degradation" EXACT [GOC:TermGenie] is_a: GO:1901575 ! organic substance catabolic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion relationship: has_primary_input CHEBI:78608 ! alpha-amino acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:54Z [Term] id: GO:1901607 name: alpha-amino acid biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of an alpha-amino acid." [GOC:TermGenie] synonym: "alpha-amino acid anabolism" EXACT [GOC:TermGenie] synonym: "alpha-amino acid biosynthesis" EXACT [GOC:TermGenie] synonym: "alpha-amino acid formation" EXACT [GOC:TermGenie] synonym: "alpha-amino acid synthesis" EXACT [GOC:TermGenie] is_a: GO:0008652 ! amino acid biosynthetic process is_a: GO:1901605 ! alpha-amino acid metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion relationship: has_primary_output CHEBI:78608 ! alpha-amino acid zwitterion created_by: tb creation_date: 2012-11-08T17:39:58Z [Term] id: GO:1901608 name: regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0047496 ! vesicle transport along microtubule relationship: regulates GO:0047496 ! vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:44Z [Term] id: GO:1901609 name: negative regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "down regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "down-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "downregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "inhibition of vesicle transport along microtubule" NARROW [GOC:TermGenie] synonym: "negative regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0047496 ! vesicle transport along microtubule relationship: negatively_regulates GO:0047496 ! vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:48Z [Term] id: GO:1901610 name: positive regulation of vesicle transport along microtubule namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." [GOC:TermGenie] synonym: "activation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "activation of vesicle transport along microtubule" NARROW [GOC:TermGenie] synonym: "positive regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "up-regulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-based vesicle localization" EXACT [GOC:TermGenie] synonym: "upregulation of vesicle transport along microtubule" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1901608 ! regulation of vesicle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0047496 ! vesicle transport along microtubule relationship: positively_regulates GO:0047496 ! vesicle transport along microtubule created_by: hjd creation_date: 2012-11-08T21:49:53Z [Term] id: GO:1901615 name: organic hydroxy compound metabolic process namespace: biological_process def: "The chemical reactions and pathways involving organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound metabolism" EXACT [GOC:TermGenie] is_a: GO:0071704 ! organic substance metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input_or_output CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:54:27Z [Term] id: GO:1901616 name: organic hydroxy compound catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound breakdown" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound catabolism" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound degradation" EXACT [GOC:TermGenie] is_a: GO:1901575 ! organic substance catabolic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009056 ! catabolic process intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:54:31Z [Term] id: GO:1901617 name: organic hydroxy compound biosynthetic process namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of organic hydroxy compound." [GOC:pr, GOC:TermGenie] synonym: "organic hydroxy compound anabolism" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound biosynthesis" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound formation" EXACT [GOC:TermGenie] synonym: "organic hydroxy compound synthesis" EXACT [GOC:TermGenie] is_a: GO:1901576 ! organic substance biosynthetic process is_a: GO:1901615 ! organic hydroxy compound metabolic process intersection_of: GO:0009058 ! biosynthetic process intersection_of: has_primary_output CHEBI:33822 ! organic hydroxy compound relationship: has_primary_output CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:54:36Z [Term] id: GO:1901618 name: organic hydroxy compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of organic hydroxy compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:33822 ! organic hydroxy compound relationship: has_primary_input CHEBI:33822 ! organic hydroxy compound created_by: pr creation_date: 2012-11-13T12:59:01Z [Term] id: GO:1901652 name: response to peptide namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus." [GOC:pr, GOC:TermGenie] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:16670 ! peptide relationship: has_input CHEBI:16670 ! peptide created_by: pr creation_date: 2012-11-20T09:45:15Z [Term] id: GO:1901654 name: response to ketone namespace: biological_process alt_id: GO:1990369 def: "A response that results in a state of tolerance to ketone." [GOC:mengo_curators, PMID:23356676] synonym: "process resulting in tolerance to ketone" NARROW [] is_a: GO:0010033 ! response to organic substance is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:17087 ! ketone relationship: has_input CHEBI:17087 ! ketone created_by: pr creation_date: 2012-11-20T10:55:47Z [Term] id: GO:1901682 name: sulfur compound transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of a sulfur compound from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] synonym: "sulfur molecular entity transmembrane transporter activity" EXACT [] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:26835 ! sulfur molecular entity relationship: has_primary_input CHEBI:26835 ! sulfur molecular entity created_by: pr creation_date: 2012-11-26T20:45:29Z [Term] id: GO:1901692 name: regulation of compound eye retinal cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990010 ! compound eye retinal cell apoptotic process relationship: regulates GO:1990010 ! compound eye retinal cell apoptotic process created_by: pr creation_date: 2012-12-12T10:28:35Z [Term] id: GO:1901693 name: negative regulation of compound eye retinal cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "down regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process relationship: negatively_regulates GO:1990010 ! compound eye retinal cell apoptotic process created_by: pr creation_date: 2012-12-12T10:28:40Z [Term] id: GO:1901694 name: positive regulation of compound eye retinal cell apoptotic process namespace: biological_process alt_id: GO:0046675 def: "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process." [GOC:mtg_apoptosis, GOC:TermGenie, PMID:12021768] synonym: "activation of compound eye retinal cell apoptotic process" NARROW [GOC:TermGenie] synonym: "induction of compound eye retinal cell programmed cell death" RELATED [] synonym: "up regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of compound eye retinal cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0046672 ! positive regulation of compound eye retinal cell programmed cell death is_a: GO:1901692 ! regulation of compound eye retinal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process relationship: positively_regulates GO:1990010 ! compound eye retinal cell apoptotic process created_by: pr creation_date: 2012-12-12T10:28:45Z [Term] id: GO:1901698 name: response to nitrogen compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "response to nitrogen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:51143 ! nitrogen molecular entity relationship: has_input CHEBI:51143 ! nitrogen molecular entity created_by: pr creation_date: 2012-12-13T15:06:08Z [Term] id: GO:1901700 name: response to oxygen-containing compound namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." [GOC:pr, GOC:TermGenie] synonym: "response to oxygen molecular entity" EXACT [] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:25806 ! oxygen molecular entity relationship: has_input CHEBI:25806 ! oxygen molecular entity created_by: pr creation_date: 2012-12-13T15:11:37Z [Term] id: GO:1901702 name: salt transmembrane transporter activity namespace: molecular_function def: "Enables the transfer of salt from one side of a membrane to the other." [GOC:pr, GOC:TermGenie] is_a: GO:0022857 ! transmembrane transporter activity intersection_of: GO:0022857 ! transmembrane transporter activity intersection_of: has_primary_input CHEBI:24866 ! salt relationship: has_primary_input CHEBI:24866 ! salt created_by: pr creation_date: 2012-12-13T15:14:47Z [Term] id: GO:1901706 name: mesenchymal cell differentiation involved in bone development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state." [GOC:hjd, GOC:TermGenie, PMID:21571217] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0060348 ! bone development relationship: part_of GO:0060348 ! bone development created_by: hjd creation_date: 2012-12-14T16:04:16Z [Term] id: GO:1901722 name: regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072111 ! cell proliferation involved in kidney development relationship: regulates GO:0072111 ! cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:31Z [Term] id: GO:1901723 name: negative regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "down regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "inhibition of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development relationship: negatively_regulates GO:0072111 ! cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:35Z [Term] id: GO:1901724 name: positive regulation of cell proliferation involved in kidney development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development." [GOC:TermGenie, PMID:18182616] synonym: "activation of cell proliferation involved in kidney development" NARROW [GOC:TermGenie] synonym: "up regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in kidney development" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072111 ! cell proliferation involved in kidney development relationship: positively_regulates GO:0072111 ! cell proliferation involved in kidney development created_by: krc creation_date: 2012-12-27T19:30:40Z [Term] id: GO:1901861 name: regulation of muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060537 ! muscle tissue development relationship: regulates GO:0060537 ! muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:47Z [Term] id: GO:1901862 name: negative regulation of muscle tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "down regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of muscle tissue development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060537 ! muscle tissue development relationship: negatively_regulates GO:0060537 ! muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:52Z [Term] id: GO:1901863 name: positive regulation of muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of muscle tissue development." [GOC:TermGenie, GOC:yaf, PMID:23150719] synonym: "activation of muscle tissue development" NARROW [GOC:TermGenie] synonym: "up regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060537 ! muscle tissue development relationship: positively_regulates GO:0060537 ! muscle tissue development created_by: yaf creation_date: 2013-02-01T10:30:57Z [Term] id: GO:1901879 name: regulation of protein depolymerization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043244 ! regulation of protein-containing complex disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051261 ! protein depolymerization relationship: regulates GO:0051261 ! protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:23Z [Term] id: GO:1901880 name: negative regulation of protein depolymerization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "down regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "downregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "inhibition of protein depolymerization" NARROW [GOC:TermGenie] synonym: "inhibition of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "inhibition of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043242 ! negative regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051261 ! protein depolymerization relationship: negatively_regulates GO:0051261 ! protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:28Z [Term] id: GO:1901881 name: positive regulation of protein depolymerization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein depolymerization." [GOC:BHF, GOC:rl, GOC:TermGenie, PMID:12032137] synonym: "activation of protein depolymerization" NARROW [GOC:TermGenie] synonym: "activation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "activation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "activation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of protein polymer degradation" EXACT [GOC:TermGenie] synonym: "upregulation of protein depolymerization" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of protein polymer degradation" EXACT [GOC:TermGenie] is_a: GO:0043243 ! positive regulation of protein-containing complex disassembly is_a: GO:1901879 ! regulation of protein depolymerization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051261 ! protein depolymerization relationship: positively_regulates GO:0051261 ! protein depolymerization created_by: rl creation_date: 2013-02-06T13:57:32Z [Term] id: GO:1901888 name: regulation of cell junction assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] is_a: GO:0044087 ! regulation of cellular component biogenesis is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0034329 ! cell junction assembly relationship: regulates GO:0034329 ! cell junction assembly created_by: tb creation_date: 2013-02-06T19:40:32Z [Term] id: GO:1901889 name: negative regulation of cell junction assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "down regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "inhibition of cell junction assembly" NARROW [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0034329 ! cell junction assembly relationship: negatively_regulates GO:0034329 ! cell junction assembly created_by: tb creation_date: 2013-02-06T19:40:41Z [Term] id: GO:1901890 name: positive regulation of cell junction assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell junction assembly." [GOC:TermGenie] synonym: "activation of cell junction assembly" NARROW [GOC:TermGenie] synonym: "up regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell junction assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell junction assembly" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1901888 ! regulation of cell junction assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0034329 ! cell junction assembly relationship: positively_regulates GO:0034329 ! cell junction assembly created_by: tb creation_date: 2013-02-06T19:40:46Z [Term] id: GO:1901963 name: regulation of cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis relationship: regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis created_by: dph creation_date: 2013-02-20T20:30:26Z [Term] id: GO:1901964 name: positive regulation of cell proliferation involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_heart, GOC:TermGenie, PMID:21419760] synonym: "activation of cell proliferation involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1901963 ! regulation of cell proliferation involved in outflow tract morphogenesis is_a: GO:2000138 ! positive regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis relationship: positively_regulates GO:0061325 ! cell proliferation involved in outflow tract morphogenesis created_by: dph creation_date: 2013-02-20T20:30:31Z [Term] id: GO:1902017 name: regulation of cilium assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "regulation of cilium biogenesis" RELATED [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060271 ! cilium assembly relationship: regulates GO:0060271 ! cilium assembly created_by: dph creation_date: 2013-03-26T18:10:51Z [Term] id: GO:1902018 name: negative regulation of cilium assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly." [GOC:cilia, GOC:dph, GOC:TermGenie, PMID:17719545] synonym: "down regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cilium assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of ciliogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cilium assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cilium biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of ciliogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of cilium biogenesis" RELATED [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1902017 ! regulation of cilium assembly is_a: GO:1902116 ! negative regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060271 ! cilium assembly relationship: negatively_regulates GO:0060271 ! cilium assembly created_by: dph creation_date: 2013-03-26T18:10:56Z [Term] id: GO:1902019 name: regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "regulation of ciliary cell motility" RELATED [] synonym: "regulation of cilium cell motility" EXACT [] is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060285 ! cilium-dependent cell motility relationship: regulates GO:0060285 ! cilium-dependent cell motility created_by: jl creation_date: 2013-03-27T14:42:38Z [Term] id: GO:1902020 name: negative regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl, GOC:TermGenie] synonym: "down regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "down-regulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "downregulation of ciliary cell motility" EXACT [GOC:TermGenie] synonym: "inhibition of ciliary cell motility" NARROW [GOC:TermGenie] synonym: "negative regulation of ciliary cell motility" RELATED [] synonym: "negative regulation of cilium cell motility" EXACT [] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000146 ! negative regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060285 ! cilium-dependent cell motility relationship: negatively_regulates GO:0060285 ! cilium-dependent cell motility created_by: jl creation_date: 2013-03-27T14:42:42Z [Term] id: GO:1902033 name: regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071425 ! hematopoietic stem cell proliferation relationship: regulates GO:0071425 ! hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:19Z [Term] id: GO:1902034 name: negative regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:1903707 ! negative regulation of hemopoiesis is_a: GO:2000647 ! negative regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation relationship: negatively_regulates GO:0071425 ! hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:24Z [Term] id: GO:1902035 name: positive regulation of hematopoietic stem cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation." [GOC:TermGenie, PMID:23403623] synonym: "activation of hematopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of hemopoietic stem cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell proliferation" EXACT [GOC:TermGenie] is_a: GO:1902033 ! regulation of hematopoietic stem cell proliferation is_a: GO:2000648 ! positive regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation relationship: positively_regulates GO:0071425 ! hematopoietic stem cell proliferation created_by: ss creation_date: 2013-04-02T05:13:31Z [Term] id: GO:1902036 name: regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060218 ! hematopoietic stem cell differentiation relationship: regulates GO:0060218 ! hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:09Z [Term] id: GO:1902037 name: negative regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "down regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation relationship: negatively_regulates GO:0060218 ! hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:14Z [Term] id: GO:1902038 name: positive regulation of hematopoietic stem cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation." [GOC:TermGenie, PMID:23403623] synonym: "activation of haematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of haemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of hematopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of hemopoietic stem cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoietic stem cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoietic stem cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1902036 ! regulation of hematopoietic stem cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation relationship: positively_regulates GO:0060218 ! hematopoietic stem cell differentiation created_by: ss creation_date: 2013-04-02T05:19:19Z [Term] id: GO:1902074 name: response to salt namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." [GOC:mls, GOC:TermGenie, PMID:16666921] synonym: "response to salinity" NARROW [GOC:mls] is_a: GO:0042221 ! response to chemical intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:24866 ! salt relationship: has_input CHEBI:24866 ! salt created_by: mls creation_date: 2013-04-22T15:41:57Z [Term] id: GO:1902093 name: positive regulation of flagellated sperm motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility." [GOC:cilia, GOC:jh2, GOC:krc, GOC:TermGenie, PMID:7513657] synonym: "activation of sperm motility" NARROW [GOC:TermGenie] synonym: "activation of sperm movement" BROAD [GOC:TermGenie] synonym: "positive regulation of sperm motility" BROAD [] synonym: "positive regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "up regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "up regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "up-regulation of sperm motility" BROAD [GOC:TermGenie] synonym: "up-regulation of sperm movement" BROAD [GOC:TermGenie] synonym: "upregulation of sperm motility" BROAD [GOC:TermGenie] synonym: "upregulation of sperm movement" BROAD [GOC:TermGenie] is_a: GO:0003353 ! positive regulation of cilium movement is_a: GO:1901317 ! regulation of flagellated sperm motility is_a: GO:2000155 ! positive regulation of cilium-dependent cell motility is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030317 ! flagellated sperm motility relationship: positively_regulates GO:0030317 ! flagellated sperm motility created_by: bf creation_date: 2013-04-29T09:15:25Z [Term] id: GO:1902105 name: regulation of leukocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002521 ! leukocyte differentiation relationship: regulates GO:0002521 ! leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:42Z [Term] id: GO:1902106 name: negative regulation of leukocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "down regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of immune cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of leucocyte differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of leucocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903707 ! negative regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002521 ! leukocyte differentiation relationship: negatively_regulates GO:0002521 ! leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:47Z [Term] id: GO:1902107 name: positive regulation of leukocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation." [GOC:add, GOC:TermGenie] synonym: "activation of immune cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of leucocyte differentiation" NARROW [GOC:TermGenie] synonym: "activation of leukocyte differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of immune cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leucocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte differentiation" EXACT [GOC:TermGenie] is_a: GO:1902105 ! regulation of leukocyte differentiation is_a: GO:1903708 ! positive regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002521 ! leukocyte differentiation relationship: positively_regulates GO:0002521 ! leukocyte differentiation created_by: pr creation_date: 2013-05-02T17:32:52Z [Term] id: GO:1902115 name: regulation of organelle assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization is_a: GO:0044087 ! regulation of cellular component biogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0070925 ! organelle assembly relationship: regulates GO:0070925 ! organelle assembly created_by: pr creation_date: 2013-05-14T09:43:21Z [Term] id: GO:1902116 name: negative regulation of organelle assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "down regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "downregulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "inhibition of organelle assembly" NARROW [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0070925 ! organelle assembly relationship: negatively_regulates GO:0070925 ! organelle assembly created_by: pr creation_date: 2013-05-14T09:43:31Z [Term] id: GO:1902117 name: positive regulation of organelle assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of organelle assembly." [GOC:pr, GOC:TermGenie] synonym: "activation of organelle assembly" NARROW [GOC:TermGenie] synonym: "up regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of organelle assembly" EXACT [GOC:TermGenie] synonym: "upregulation of organelle assembly" EXACT [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0070925 ! organelle assembly relationship: positively_regulates GO:0070925 ! organelle assembly created_by: pr creation_date: 2013-05-14T09:43:36Z [Term] id: GO:1902217 name: erythrocyte apoptotic process namespace: biological_process def: "Any apoptotic process in an erythrocyte." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "RBC apoptosis" NARROW [GOC:TermGenie] synonym: "RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033028 ! myeloid cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000232 ! erythrocyte relationship: occurs_in CL:0000232 ! erythrocyte property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-13T10:02:29Z [Term] id: GO:1902250 name: regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033032 ! regulation of myeloid cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902217 ! erythrocyte apoptotic process relationship: regulates GO:1902217 ! erythrocyte apoptotic process created_by: rl creation_date: 2013-06-20T19:30:53Z [Term] id: GO:1902251 name: negative regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "down regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of erythrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of RBC apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of red blood cell apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033033 ! negative regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902217 ! erythrocyte apoptotic process relationship: negatively_regulates GO:1902217 ! erythrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-20T19:30:59Z [Term] id: GO:1902252 name: positive regulation of erythrocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis, GOC:rl, GOC:TermGenie, PMID:14569084] synonym: "activation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of erythrocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "activation of RBC apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of red blood cell apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of erythrocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of erythrocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of RBC apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of RBC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of red blood cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of red blood cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0033034 ! positive regulation of myeloid cell apoptotic process is_a: GO:1902250 ! regulation of erythrocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902217 ! erythrocyte apoptotic process relationship: positively_regulates GO:1902217 ! erythrocyte apoptotic process property_value: RO:0002161 NCBITaxon:4751 created_by: rl creation_date: 2013-06-20T19:31:04Z [Term] id: GO:1902256 name: regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis relationship: regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:24Z [Term] id: GO:1902257 name: negative regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "down regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902338 ! negative regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis relationship: negatively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:30Z [Term] id: GO:1902258 name: positive regulation of apoptotic process involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16839542] synonym: "activation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptosis involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1902256 ! regulation of apoptotic process involved in outflow tract morphogenesis is_a: GO:1902339 ! positive regulation of apoptotic process involved in morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis relationship: positively_regulates GO:0003275 ! apoptotic process involved in outflow tract morphogenesis created_by: dph creation_date: 2013-06-24T19:12:42Z [Term] id: GO:1902262 name: apoptotic process involved in blood vessel morphogenesis namespace: biological_process def: "Any apoptotic process that is involved in blood vessel morphogenesis." [GOC:dph, GOC:mtg_apoptosis, GOC:TermGenie, PMID:16163358] synonym: "apoptosis involved in patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "apoptotic cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "apoptotic program involved in patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in patterning of blood vessels" RELATED [GOC:TermGenie] synonym: "type I programmed cell death involved in patterning of blood vessels" NARROW [GOC:TermGenie] is_a: GO:0060561 ! apoptotic process involved in morphogenesis intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0048514 ! blood vessel morphogenesis relationship: part_of GO:0048514 ! blood vessel morphogenesis created_by: dph creation_date: 2013-06-25T16:16:00Z [Term] id: GO:1902275 name: regulation of chromatin organization namespace: biological_process alt_id: GO:0001672 alt_id: GO:1903308 def: "Any process that modulates the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:bf, GOC:TermGenie, GOC:vw, PMID:18314879] synonym: "regulation of chromatin assembly or disassembly" RELATED [] synonym: "regulation of chromatin assembly/disassembly" RELATED [] synonym: "regulation of chromatin modification" RELATED [] synonym: "regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006325 ! chromatin organization relationship: regulates GO:0006325 ! chromatin organization created_by: bf creation_date: 2013-07-01T13:21:52Z [Term] id: GO:1902305 name: regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0002028 ! regulation of sodium ion transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035725 ! sodium ion transmembrane transport relationship: regulates GO:0035725 ! sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:33:53Z [Term] id: GO:1902306 name: negative regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "down regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "inhibition of sodium ion membrane transport" NARROW [GOC:TermGenie] synonym: "inhibition of sodium ion transmembrane transport" NARROW [GOC:TermGenie] synonym: "negative regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] is_a: GO:0010766 ! negative regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904063 ! negative regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035725 ! sodium ion transmembrane transport relationship: negatively_regulates GO:0035725 ! sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:34:01Z [Term] id: GO:1902307 name: positive regulation of sodium ion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport." [GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rl, GOC:TermGenie, PMID:18591664] synonym: "activation of sodium ion membrane transport" NARROW [GOC:TermGenie] synonym: "activation of sodium ion transmembrane transport" NARROW [GOC:TermGenie] synonym: "positive regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of sodium ion transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0010765 ! positive regulation of sodium ion transport is_a: GO:1902305 ! regulation of sodium ion transmembrane transport is_a: GO:1904064 ! positive regulation of cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035725 ! sodium ion transmembrane transport relationship: positively_regulates GO:0035725 ! sodium ion transmembrane transport created_by: rl creation_date: 2013-07-18T13:34:18Z [Term] id: GO:1902337 name: regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060561 ! apoptotic process involved in morphogenesis relationship: regulates GO:0060561 ! apoptotic process involved in morphogenesis created_by: sart creation_date: 2013-07-29T15:03:16Z [Term] id: GO:1902338 name: negative regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "down regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904746 ! negative regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis relationship: negatively_regulates GO:0060561 ! apoptotic process involved in morphogenesis created_by: sart creation_date: 2013-07-29T15:03:25Z [Term] id: GO:1902339 name: positive regulation of apoptotic process involved in morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." [GOC:sart, GOC:TermGenie, PMID:12202035] synonym: "activation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "activation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in development" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in morphogenesis" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of morphogenetic apoptosis" RELATED [GOC:TermGenie] is_a: GO:1902337 ! regulation of apoptotic process involved in morphogenesis is_a: GO:1904747 ! positive regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis relationship: positively_regulates GO:0060561 ! apoptotic process involved in morphogenesis created_by: sart creation_date: 2013-07-29T15:03:33Z [Term] id: GO:1902340 name: negative regulation of chromosome condensation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." [GOC:TermGenie, PMID:23219725] synonym: "down regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "inhibition of chromosome condensation" NARROW [GOC:TermGenie] synonym: "inhibition of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear chromosome condensation" NARROW [GOC:TermGenie] synonym: "negative regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001251 ! negative regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030261 ! chromosome condensation relationship: negatively_regulates GO:0030261 ! chromosome condensation created_by: dgf creation_date: 2013-07-29T20:54:14Z [Term] id: GO:1902358 name: sulfate transmembrane transport namespace: biological_process def: "The directed movement of sulfate across a membrane." [GOC:dph, GOC:TermGenie, PMID:9055073] is_a: GO:0008272 ! sulfate transport is_a: GO:0098661 ! inorganic anion transmembrane transport intersection_of: GO:0055085 ! transmembrane transport intersection_of: has_primary_input CHEBI:16189 ! sulfate created_by: dph creation_date: 2013-08-14T14:46:04Z [Term] id: GO:1902369 name: negative regulation of RNA catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." [GOC:bf, GOC:TermGenie, PMID:16640457] synonym: "down regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA degradation" EXACT [GOC:TermGenie] synonym: "inhibition of RNA breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of RNA catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of RNA catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of RNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of RNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0051253 ! negative regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006401 ! RNA catabolic process relationship: negatively_regulates GO:0006401 ! RNA catabolic process created_by: bf creation_date: 2013-08-22T14:59:39Z [Term] id: GO:1902414 name: protein localization to cell junction namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cell junction." [GOC:TermGenie, PMID:18332111] synonym: "protein localisation in cell junction" EXACT [GOC:TermGenie] synonym: "protein localisation to cell junction" EXACT [GOC:TermGenie] synonym: "protein localization in cell junction" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0030054 ! cell junction relationship: has_target_end_location GO:0030054 ! cell junction created_by: tb creation_date: 2013-09-13T16:55:57Z [Term] id: GO:1902455 name: negative regulation of stem cell population maintenance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "down regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "downregulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "inhibition of stem cell maintenance" NARROW [GOC:TermGenie] synonym: "negative regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019827 ! stem cell population maintenance relationship: negatively_regulates GO:0019827 ! stem cell population maintenance created_by: cjm creation_date: 2013-10-16T22:19:17Z [Term] id: GO:1902459 name: positive regulation of stem cell population maintenance namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance." [GOC:hjd, GOC:TermGenie, PMID:22969033] synonym: "activation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "activation of stem cell maintenance" NARROW [GOC:TermGenie] synonym: "positive regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "up-regulation of stem cell maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "upregulation of stem cell maintenance" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019827 ! stem cell population maintenance relationship: positively_regulates GO:0019827 ! stem cell population maintenance created_by: cjm creation_date: 2013-10-16T22:27:47Z [Term] id: GO:1902463 name: protein localization to cell leading edge namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cell leading edge." [GOC:lb, GOC:TermGenie, PMID:21543326] synonym: "protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0031252 ! cell leading edge relationship: has_target_end_location GO:0031252 ! cell leading edge created_by: jl creation_date: 2013-10-22T12:36:07Z [Term] id: GO:1902473 name: regulation of protein localization to synapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "regulation of protein localisation to synapse" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035418 ! protein localization to synapse relationship: regulates GO:0035418 ! protein localization to synapse created_by: kmv creation_date: 2013-10-25T15:09:09Z [Term] id: GO:1902474 name: positive regulation of protein localization to synapse namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to synapse." [GOC:kmv, GOC:TermGenie, PMID:22588719] synonym: "activation of protein localisation to synapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization to synapse" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to synapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to synapse" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035418 ! protein localization to synapse relationship: positively_regulates GO:0035418 ! protein localization to synapse created_by: kmv creation_date: 2013-10-25T15:09:18Z [Term] id: GO:1902484 name: Sertoli cell apoptotic process namespace: biological_process def: "Any apoptotic process in a Sertoli cell." [GOC:ic, GOC:TermGenie, PMID:17761895] synonym: "Sertoli cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000216 ! Sertoli cell relationship: occurs_in CL:0000216 ! Sertoli cell created_by: pr creation_date: 2013-11-06T11:27:34Z [Term] id: GO:1902488 name: cholangiocyte apoptotic process namespace: biological_process def: "Any apoptotic process in a cholangiocyte." [GOC:TermGenie, PMID:22961800] synonym: "cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904019 ! epithelial cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:1000488 ! cholangiocyte relationship: occurs_in CL:1000488 ! cholangiocyte created_by: cls creation_date: 2013-11-12T15:30:08Z [Term] id: GO:1902489 name: hepatoblast apoptotic process namespace: biological_process def: "Any apoptotic process in a hepatoblast." [GOC:TermGenie, PMID:22412967] synonym: "hepatoblast apoptosis" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0005026 ! hepatoblast relationship: occurs_in CL:0005026 ! hepatoblast created_by: cls creation_date: 2013-11-12T17:02:52Z [Term] id: GO:1902490 name: regulation of sperm capacitation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "regulation of sperm activation" RELATED [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:1903429 ! regulation of cell maturation is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048240 ! sperm capacitation relationship: regulates GO:0048240 ! sperm capacitation created_by: hjd creation_date: 2013-11-12T21:17:03Z [Term] id: GO:1902491 name: negative regulation of sperm capacitation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "down regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "down regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "down-regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "down-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "downregulation of sperm activation" RELATED [GOC:TermGenie] synonym: "downregulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "inhibition of sperm activation" RELATED [GOC:TermGenie] synonym: "inhibition of sperm capacitation" NARROW [GOC:TermGenie] synonym: "negative regulation of sperm activation" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903430 ! negative regulation of cell maturation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048240 ! sperm capacitation relationship: negatively_regulates GO:0048240 ! sperm capacitation created_by: hjd creation_date: 2013-11-12T21:17:12Z [Term] id: GO:1902492 name: positive regulation of sperm capacitation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sperm capacitation." [GOC:hjd, GOC:TermGenie, PMID:22539676] synonym: "activation of sperm activation" RELATED [GOC:TermGenie] synonym: "activation of sperm capacitation" NARROW [GOC:TermGenie] synonym: "positive regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "up-regulation of sperm activation" RELATED [GOC:TermGenie] synonym: "up-regulation of sperm capacitation" EXACT [GOC:TermGenie] synonym: "upregulation of sperm activation" RELATED [GOC:TermGenie] synonym: "upregulation of sperm capacitation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902490 ! regulation of sperm capacitation is_a: GO:1903431 ! positive regulation of cell maturation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048240 ! sperm capacitation relationship: positively_regulates GO:0048240 ! sperm capacitation created_by: hjd creation_date: 2013-11-12T21:17:21Z [Term] id: GO:1902494 name: catalytic complex namespace: cellular_component def: "A protein complex which is capable of catalytic activity." [GOC:bhm, GOC:TermGenie, PMID:8077207] subset: goslim_metagenomics synonym: "enzyme complex" EXACT [GOC:bhm, GOC:jl] is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0003824 ! catalytic activity relationship: capable_of GO:0003824 ! catalytic activity property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/19980" xsd:anyURI created_by: bhm creation_date: 2013-11-13T16:18:47Z [Term] id: GO:1902495 name: transmembrane transporter complex namespace: cellular_component def: "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other." [GOC:bhm, GOC:TermGenie, PMID:18024586] is_a: GO:0098796 ! membrane protein complex is_a: GO:1990351 ! transporter complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0022857 ! transmembrane transporter activity relationship: capable_of GO:0022857 ! transmembrane transporter activity created_by: bhm creation_date: 2013-11-13T16:23:04Z [Term] id: GO:1902510 name: regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351, PMID:15723341] comment: DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341). synonym: "regulation of chromatinolysis" BROAD [GOC:TermGenie] synonym: "regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "regulation of DNA fragmentation" BROAD [GOC:TermGenie] synonym: "regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006309 ! apoptotic DNA fragmentation relationship: regulates GO:0006309 ! apoptotic DNA fragmentation created_by: hjd creation_date: 2013-11-15T18:28:32Z [Term] id: GO:1902511 name: negative regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] synonym: "down regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "down regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "down regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "down-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "downregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "downregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "inhibition of apoptotic DNA fragmentation" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolism during apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie] synonym: "inhibition of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "negative regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation is_a: GO:1903625 ! negative regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation relationship: negatively_regulates GO:0006309 ! apoptotic DNA fragmentation created_by: hjd creation_date: 2013-11-15T18:28:41Z [Term] id: GO:1902512 name: positive regulation of apoptotic DNA fragmentation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation." [GOC:hjd, GOC:TermGenie, PMID:15572351] synonym: "activation of apoptotic DNA fragmentation" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolic process during apoptosis" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolism during apoptosis" NARROW [GOC:TermGenie] synonym: "activation of DNA fragmentation involved in apoptotic nuclear change" NARROW [GOC:TermGenie] synonym: "activation of endonucleolytic DNA catabolic process involved in apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "positive regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "up regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "up regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "up-regulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic DNA fragmentation" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolic process during apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolism during apoptosis" EXACT [GOC:TermGenie] synonym: "upregulation of DNA fragmentation involved in apoptotic nuclear change" EXACT [GOC:TermGenie] synonym: "upregulation of endonucleolytic DNA catabolic process involved in apoptosis" EXACT [GOC:TermGenie] is_a: GO:1902510 ! regulation of apoptotic DNA fragmentation is_a: GO:1903626 ! positive regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006309 ! apoptotic DNA fragmentation relationship: positively_regulates GO:0006309 ! apoptotic DNA fragmentation created_by: hjd creation_date: 2013-11-15T18:28:50Z [Term] id: GO:1902513 name: regulation of organelle transport along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." [GOC:dph, GOC:TermGenie, PMID:21147087] synonym: "regulation of microtubule-based organelle localization" EXACT [GOC:TermGenie] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072384 ! organelle transport along microtubule relationship: regulates GO:0072384 ! organelle transport along microtubule created_by: dph creation_date: 2013-11-15T20:15:17Z [Term] id: GO:1902531 name: regulation of intracellular signal transduction namespace: biological_process alt_id: GO:0010627 def: "Any process that modulates the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "regulation of intracellular protein kinase cascade" NARROW [] synonym: "regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009966 ! regulation of signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035556 ! intracellular signal transduction relationship: regulates GO:0035556 ! intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:32:52Z [Term] id: GO:1902532 name: negative regulation of intracellular signal transduction namespace: biological_process alt_id: GO:0010741 def: "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." [GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "down regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "down regulation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "down regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "down regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "down regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "down-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "down-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "down-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "down-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "down-regulation of signal transmission via intracellular cascade" RELATED [GOC:TermGenie] synonym: "downregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "downregulation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "downregulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "downregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "downregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "downregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signal transduction" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling chain" NARROW [GOC:TermGenie] synonym: "inhibition of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "inhibition of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "inhibition of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "negative regulation of intracellular protein kinase cascade" EXACT [] synonym: "negative regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "negative regulation of intracellular signaling cascade" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "negative regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "negative regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "negative regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035556 ! intracellular signal transduction relationship: negatively_regulates GO:0035556 ! intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:33:01Z [Term] id: GO:1902533 name: positive regulation of intracellular signal transduction namespace: biological_process alt_id: GO:0010740 def: "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." [GOC:BHF, GOC:dph, GOC:signaling, GOC:tb, GOC:TermGenie] synonym: "activation of intracellular signal transduction" NARROW [GOC:TermGenie] synonym: "activation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling cascade" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling chain" NARROW [GOC:TermGenie] synonym: "activation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "activation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "activation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "positive regulation of intracellular protein kinase cascade" NARROW [] synonym: "positive regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "positive regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "positive regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "positive regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "positive regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "positive regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "up regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "up regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "up regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "up-regulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "up-regulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up-regulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "up-regulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "up-regulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "up-regulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] synonym: "upregulation of intracellular signal transduction" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signal transduction pathway" NARROW [GOC:TermGenie] synonym: "upregulation of intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "upregulation of intracellular signaling chain" EXACT [GOC:TermGenie] synonym: "upregulation of intracellular signaling pathway" RELATED [GOC:TermGenie] synonym: "upregulation of signal transduction via intracellular signaling cascade" RELATED [GOC:TermGenie] synonym: "upregulation of signal transmission via intracellular cascade" NARROW [GOC:TermGenie] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:1902531 ! regulation of intracellular signal transduction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035556 ! intracellular signal transduction relationship: positively_regulates GO:0035556 ! intracellular signal transduction created_by: bf creation_date: 2013-12-02T11:33:10Z [Term] id: GO:1902570 name: protein localization to nucleolus namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a nucleolus." [GOC:TermGenie, PMID:22809626] synonym: "protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:0034504 ! protein localization to nucleus intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005730 ! nucleolus relationship: has_target_end_location GO:0005730 ! nucleolus created_by: mah creation_date: 2013-12-10T16:25:28Z [Term] id: GO:1902679 name: negative regulation of RNA biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "down regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "down-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "downregulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of RNA anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of RNA biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of RNA biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of RNA formation" NARROW [GOC:TermGenie] synonym: "inhibition of RNA synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "negative regulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0051253 ! negative regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032774 ! RNA biosynthetic process relationship: negatively_regulates GO:0032774 ! RNA biosynthetic process created_by: jl creation_date: 2014-02-05T16:32:01Z [Term] id: GO:1902680 name: positive regulation of RNA biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." [GO:jl, GO_REF:0000058, GOC:TermGenie] synonym: "activation of RNA anabolism" NARROW [GOC:TermGenie] synonym: "activation of RNA biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of RNA biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of RNA formation" NARROW [GOC:TermGenie] synonym: "activation of RNA synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "positive regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA formation" EXACT [GOC:TermGenie] synonym: "up-regulation of RNA synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of RNA biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of RNA formation" EXACT [GOC:TermGenie] synonym: "upregulation of RNA synthesis" EXACT [GOC:TermGenie] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0051254 ! positive regulation of RNA metabolic process is_a: GO:2001141 ! regulation of RNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032774 ! RNA biosynthetic process relationship: positively_regulates GO:0032774 ! RNA biosynthetic process created_by: jl creation_date: 2014-02-05T16:32:10Z [Term] id: GO:1902692 name: regulation of neuroblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuroblast proliferation." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:21168496] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007405 ! neuroblast proliferation relationship: regulates GO:0007405 ! neuroblast proliferation created_by: rl creation_date: 2014-02-18T10:03:31Z [Term] id: GO:1902738 name: regulation of chondrocyte differentiation involved in endochondral bone morphogenesis namespace: biological_process def: "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." [GO_REF:0000058, GOC:TermGenie, PMID:8662546] is_a: GO:0032330 ! regulation of chondrocyte differentiation is_a: GO:1903010 ! regulation of bone development is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis relationship: regulates GO:0003413 ! chondrocyte differentiation involved in endochondral bone morphogenesis created_by: mr creation_date: 2014-02-26T15:36:15Z [Term] id: GO:1902742 name: apoptotic process involved in development namespace: biological_process def: "Any apoptotic process that is involved in anatomical structure development." [GO_REF:0000060, GOC:mtg_apoptosis, GOC:pg, GOC:TermGenie] synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic process involved in anatomical structure development" EXACT [] synonym: "apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: part_of GO:0048856 ! anatomical structure development relationship: part_of GO:0048856 ! anatomical structure development created_by: pr creation_date: 2014-02-28T13:09:43Z [Term] id: GO:1902761 name: positive regulation of chondrocyte development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chondrocyte development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16575901] synonym: "activation of chondrocyte development" NARROW [GOC:TermGenie] synonym: "up regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "up-regulation of chondrocyte development" EXACT [GOC:TermGenie] synonym: "upregulation of chondrocyte development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0032332 ! positive regulation of chondrocyte differentiation is_a: GO:0061181 ! regulation of chondrocyte development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002063 ! chondrocyte development relationship: positively_regulates GO:0002063 ! chondrocyte development created_by: mr creation_date: 2014-03-07T17:45:55Z [Term] id: GO:1902809 name: regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] is_a: GO:0010830 ! regulation of myotube differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098528 ! skeletal muscle fiber differentiation relationship: regulates GO:0098528 ! skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:26Z [Term] id: GO:1902810 name: negative regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "down regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] is_a: GO:0010832 ! negative regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001015 ! negative regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation relationship: negatively_regulates GO:0098528 ! skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:32Z [Term] id: GO:1902811 name: positive regulation of skeletal muscle fiber differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:17879321] synonym: "activation of skeletal muscle fiber differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle fiber differentiation" EXACT [GOC:TermGenie] is_a: GO:0010831 ! positive regulation of myotube differentiation is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation is_a: GO:2001016 ! positive regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation relationship: positively_regulates GO:0098528 ! skeletal muscle fiber differentiation created_by: mr creation_date: 2014-03-26T21:18:38Z [Term] id: GO:1902816 name: regulation of protein localization to microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035372 ! protein localization to microtubule relationship: regulates GO:0035372 ! protein localization to microtubule created_by: tb creation_date: 2014-03-27T22:07:12Z [Term] id: GO:1902817 name: negative regulation of protein localization to microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule." [GO_REF:0000058, GOC:TermGenie, GOC:vw, PMID:23087209] synonym: "down regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to microtubule" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to microtubule" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to microtubule" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to microtubule" EXACT [GOC:TermGenie] is_a: GO:1902816 ! regulation of protein localization to microtubule is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035372 ! protein localization to microtubule relationship: negatively_regulates GO:0035372 ! protein localization to microtubule created_by: tb creation_date: 2014-03-27T22:07:18Z [Term] id: GO:1902838 name: regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "regulation of nuclear movement, microtubule-mediated" BROAD [GOC:TermGenie] synonym: "regulation of nucleus migration" BROAD [GOC:TermGenie] synonym: "regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:1902513 ! regulation of organelle transport along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030473 ! nuclear migration along microtubule relationship: regulates GO:0030473 ! nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:23Z [Term] id: GO:1902839 name: negative regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "down regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "down-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "down-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "downregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "downregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "inhibition of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear migration along microtubule" NARROW [GOC:TermGenie] synonym: "inhibition of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "inhibition of transport of nucleus by microtubules" NARROW [GOC:TermGenie] synonym: "inhibition of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "negative regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "negative regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030473 ! nuclear migration along microtubule relationship: negatively_regulates GO:0030473 ! nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:29Z [Term] id: GO:1902840 name: positive regulation of nuclear migration along microtubule namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule." [GO_REF:0000058, GOC:TermGenie, PMID:23087209] synonym: "activation of microtubule cytoskeleton-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule cytoskeleton-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-dependent nuclear positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-dependent nucleus positioning" NARROW [GOC:TermGenie] synonym: "activation of microtubule-mediated nuclear migration" NARROW [GOC:TermGenie] synonym: "activation of nuclear migration along microtubule" NARROW [GOC:TermGenie] synonym: "activation of nuclear migration, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "activation of transport of nucleus by microtubules" NARROW [GOC:TermGenie] synonym: "activation of transport of nucleus, microtubule-mediated" NARROW [GOC:TermGenie] synonym: "positive regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "positive regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "up-regulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule cytoskeleton-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nuclear positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-dependent nucleus positioning" EXACT [GOC:TermGenie] synonym: "upregulation of microtubule-mediated nuclear migration" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration along microtubule" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear migration, microtubule-mediated" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus by microtubules" EXACT [GOC:TermGenie] synonym: "upregulation of transport of nucleus, microtubule-mediated" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1902838 ! regulation of nuclear migration along microtubule intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030473 ! nuclear migration along microtubule relationship: positively_regulates GO:0030473 ! nuclear migration along microtubule created_by: vw creation_date: 2014-04-01T13:50:35Z [Term] id: GO:1902850 name: microtubule cytoskeleton organization involved in mitosis namespace: biological_process def: "Any microtubule cytoskeleton organization that is involved in mitosis." [GO_REF:0000060, GOC:TermGenie, PMID:18799626] synonym: "microtubule cytoskeleton organisation involved in mitosis" EXACT [GOC:TermGenie] synonym: "microtubule cytoskeleton organization and biogenesis involved in mitosis" RELATED [GOC:TermGenie] synonym: "microtubule dynamics involved in mitosis" EXACT [GOC:TermGenie] is_a: GO:0000226 ! microtubule cytoskeleton organization is_a: GO:1903047 ! mitotic cell cycle process intersection_of: GO:0000226 ! microtubule cytoskeleton organization intersection_of: part_of GO:0000278 ! mitotic cell cycle created_by: vw creation_date: 2014-04-02T14:19:38Z [Term] id: GO:1902863 name: regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0031076 ! embryonic camera-type eye development relationship: regulates GO:0031076 ! embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:00Z [Term] id: GO:1902864 name: negative regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "down-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "downregulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "inhibition of embryonic camera-type eye development" NARROW [GOC:TermGenie] synonym: "inhibition of embryonic eye development" NARROW [GOC:TermGenie] synonym: "negative regulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0031076 ! embryonic camera-type eye development relationship: negatively_regulates GO:0031076 ! embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:06Z [Term] id: GO:1902865 name: positive regulation of embryonic camera-type eye development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of embryonic camera-type eye development" NARROW [GOC:TermGenie] synonym: "activation of embryonic eye development" NARROW [GOC:TermGenie] synonym: "positive regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "up-regulation of embryonic eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic camera-type eye development" EXACT [GOC:TermGenie] synonym: "upregulation of embryonic eye development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1902863 ! regulation of embryonic camera-type eye development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0031076 ! embryonic camera-type eye development relationship: positively_regulates GO:0031076 ! embryonic camera-type eye development created_by: mr creation_date: 2014-04-03T15:24:12Z [Term] id: GO:1902866 name: regulation of retina development in camera-type eye namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "regulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060041 ! retina development in camera-type eye relationship: regulates GO:0060041 ! retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:17Z [Term] id: GO:1902867 name: negative regulation of retina development in camera-type eye namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "down regulation of retinal development" RELATED [GOC:TermGenie] synonym: "down-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "down-regulation of retinal development" RELATED [GOC:TermGenie] synonym: "downregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "downregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "downregulation of retinal development" RELATED [GOC:TermGenie] synonym: "inhibition of retina development in camera-style eye" NARROW [GOC:TermGenie] synonym: "inhibition of retina development in camera-type eye" NARROW [GOC:TermGenie] synonym: "inhibition of retinal development" RELATED [GOC:TermGenie] synonym: "negative regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "negative regulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060041 ! retina development in camera-type eye relationship: negatively_regulates GO:0060041 ! retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:23Z [Term] id: GO:1902868 name: positive regulation of retina development in camera-type eye namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of retina development in camera-style eye" NARROW [GOC:TermGenie] synonym: "activation of retina development in camera-type eye" NARROW [GOC:TermGenie] synonym: "activation of retinal development" RELATED [GOC:TermGenie] synonym: "positive regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "positive regulation of retinal development" RELATED [GOC:TermGenie] synonym: "up regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "up regulation of retinal development" RELATED [GOC:TermGenie] synonym: "up-regulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "up-regulation of retinal development" RELATED [GOC:TermGenie] synonym: "upregulation of retina development in camera-style eye" EXACT [GOC:TermGenie] synonym: "upregulation of retina development in camera-type eye" EXACT [GOC:TermGenie] synonym: "upregulation of retinal development" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902866 ! regulation of retina development in camera-type eye intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060041 ! retina development in camera-type eye relationship: positively_regulates GO:0060041 ! retina development in camera-type eye created_by: mr creation_date: 2014-04-03T15:24:29Z [Term] id: GO:1902875 name: regulation of embryonic pattern specification namespace: biological_process def: "Any process that modulates the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "regulation of embryonic pattern biosynthesis" BROAD [GOC:TermGenie] synonym: "regulation of embryonic pattern formation" BROAD [GOC:TermGenie] synonym: "regulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009880 ! embryonic pattern specification relationship: regulates GO:0009880 ! embryonic pattern specification created_by: mr creation_date: 2014-04-03T15:25:15Z [Term] id: GO:1902876 name: negative regulation of embryonic pattern specification namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "down regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "down regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "down-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "down-regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "downregulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "downregulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "inhibition of embryonic pattern specification" NARROW [GOC:TermGenie] synonym: "inhibition of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "negative regulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009880 ! embryonic pattern specification relationship: negatively_regulates GO:0009880 ! embryonic pattern specification created_by: mr creation_date: 2014-04-03T15:25:20Z [Term] id: GO:1902877 name: positive regulation of embryonic pattern specification namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16872597] synonym: "activation of embryonic pattern specification" NARROW [GOC:TermGenie] synonym: "activation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "positive regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "up regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "up regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "up-regulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "up-regulation of ventral/lateral system" RELATED [GOC:TermGenie] synonym: "upregulation of embryonic pattern specification" EXACT [GOC:TermGenie] synonym: "upregulation of ventral/lateral system" RELATED [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1902875 ! regulation of embryonic pattern specification intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009880 ! embryonic pattern specification relationship: positively_regulates GO:0009880 ! embryonic pattern specification created_by: mr creation_date: 2014-04-03T15:25:26Z [Term] id: GO:1902903 name: regulation of supramolecular fiber organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "regulation of fibril organisation" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097435 ! supramolecular fiber organization relationship: regulates GO:0097435 ! supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:36Z [Term] id: GO:1902904 name: negative regulation of supramolecular fiber organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "down regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "down regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "down-regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "down-regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "downregulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "downregulation of fibril organization" RELATED [GOC:TermGenie] synonym: "inhibition of fibril organisation" NARROW [GOC:TermGenie] synonym: "inhibition of fibril organization" NARROW [GOC:TermGenie] synonym: "negative regulation of fibril organisation" RELATED [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097435 ! supramolecular fiber organization relationship: negatively_regulates GO:0097435 ! supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:42Z [Term] id: GO:1902905 name: positive regulation of supramolecular fiber organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." [GO_REF:0000058, GOC:PARL, GOC:rl, GOC:TermGenie, PMID:23921388] comment: HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro synonym: "activation of fibril organisation" NARROW [GOC:TermGenie] synonym: "activation of fibril organization" NARROW [GOC:TermGenie] synonym: "positive regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "up-regulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "up-regulation of fibril organization" RELATED [GOC:TermGenie] synonym: "upregulation of fibril organisation" RELATED [GOC:TermGenie] synonym: "upregulation of fibril organization" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097435 ! supramolecular fiber organization relationship: positively_regulates GO:0097435 ! supramolecular fiber organization created_by: rl creation_date: 2014-04-15T16:46:48Z [Term] id: GO:1902913 name: positive regulation of neuroepithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:16916506] synonym: "activation of neuroepithelial cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neuroepithelial cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060563 ! neuroepithelial cell differentiation relationship: positively_regulates GO:0060563 ! neuroepithelial cell differentiation created_by: mr creation_date: 2014-04-18T21:06:42Z [Term] id: GO:1903008 name: organelle disassembly namespace: biological_process def: "The disaggregation of an organelle into its constituent components." [GO_REF:0000079, GOC:TermGenie] synonym: "organelle degradation" EXACT [] is_a: GO:0006996 ! organelle organization is_a: GO:0022411 ! cellular component disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0043226 ! organelle relationship: results_in_disassembly_of GO:0043226 ! organelle created_by: jl creation_date: 2014-05-13T12:36:03Z [Term] id: GO:1903010 name: regulation of bone development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060348 ! bone development relationship: regulates GO:0060348 ! bone development created_by: mr creation_date: 2014-05-13T22:41:53Z [Term] id: GO:1903011 name: negative regulation of bone development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "down regulation of bone development" EXACT [GOC:TermGenie] synonym: "down-regulation of bone development" EXACT [GOC:TermGenie] synonym: "downregulation of bone development" EXACT [GOC:TermGenie] synonym: "inhibition of bone development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060348 ! bone development relationship: negatively_regulates GO:0060348 ! bone development created_by: mr creation_date: 2014-05-13T22:42:00Z [Term] id: GO:1903012 name: positive regulation of bone development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bone development." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:22510437] synonym: "activation of bone development" NARROW [GOC:TermGenie] synonym: "up regulation of bone development" EXACT [GOC:TermGenie] synonym: "up-regulation of bone development" EXACT [GOC:TermGenie] synonym: "upregulation of bone development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903010 ! regulation of bone development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060348 ! bone development relationship: positively_regulates GO:0060348 ! bone development created_by: mr creation_date: 2014-05-13T22:42:06Z [Term] id: GO:1903018 name: regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0051246 ! regulation of protein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009100 ! glycoprotein metabolic process relationship: regulates GO:0009100 ! glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:19Z [Term] id: GO:1903019 name: negative regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "down regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of glycoprotein metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0051248 ! negative regulation of protein metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0009100 ! glycoprotein metabolic process relationship: negatively_regulates GO:0009100 ! glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:25Z [Term] id: GO:1903020 name: positive regulation of glycoprotein metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:23544079] comment: human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein synonym: "activation of glycoprotein metabolic process" NARROW [GOC:TermGenie] synonym: "activation of glycoprotein metabolism" NARROW [GOC:TermGenie] synonym: "positive regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of glycoprotein metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of glycoprotein metabolism" EXACT [GOC:TermGenie] is_a: GO:0051247 ! positive regulation of protein metabolic process is_a: GO:1903018 ! regulation of glycoprotein metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009100 ! glycoprotein metabolic process relationship: positively_regulates GO:0009100 ! glycoprotein metabolic process created_by: rl creation_date: 2014-05-14T18:44:31Z [Term] id: GO:1903037 name: regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022407 ! regulation of cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007159 ! leukocyte cell-cell adhesion relationship: regulates GO:0007159 ! leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:29:58Z [Term] id: GO:1903038 name: negative regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "down regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "down-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "downregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "inhibition of leukocyte adhesion" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte cell adhesion" NARROW [GOC:TermGenie] synonym: "inhibition of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] synonym: "negative regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "negative regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022408 ! negative regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion relationship: negatively_regulates GO:0007159 ! leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:30:05Z [Term] id: GO:1903039 name: positive regulation of leukocyte cell-cell adhesion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21106532] comment: Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion synonym: "activation of leukocyte adhesion" NARROW [GOC:TermGenie] synonym: "activation of leukocyte cell adhesion" NARROW [GOC:TermGenie] synonym: "activation of leukocyte cell-cell adhesion" NARROW [GOC:TermGenie] synonym: "positive regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "positive regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "up-regulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell adhesion" EXACT [GOC:TermGenie] synonym: "upregulation of leukocyte cell-cell adhesion" EXACT [GOC:TermGenie] is_a: GO:0022409 ! positive regulation of cell-cell adhesion is_a: GO:1903037 ! regulation of leukocyte cell-cell adhesion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion relationship: positively_regulates GO:0007159 ! leukocyte cell-cell adhesion created_by: rl creation_date: 2014-05-19T15:30:15Z [Term] id: GO:1903045 name: neural crest cell migration involved in sympathetic nervous system development namespace: biological_process def: "Any neural crest cell migration that is involved in sympathetic nervous system development." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:19325129] comment: Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development is_a: GO:1901166 ! neural crest cell migration involved in autonomic nervous system development intersection_of: GO:0001755 ! neural crest cell migration intersection_of: part_of GO:0048485 ! sympathetic nervous system development relationship: part_of GO:0048485 ! sympathetic nervous system development created_by: rl creation_date: 2014-05-22T07:06:02Z [Term] id: GO:1903046 name: meiotic cell cycle process namespace: biological_process def: "A process that is part of the meiotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] subset: gocheck_do_not_annotate subset: goslim_pombe is_a: GO:0022402 ! cell cycle process is_a: GO:0022414 ! reproductive process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0051321 ! meiotic cell cycle disjoint_from: GO:1903047 ! mitotic cell cycle process relationship: part_of GO:0051321 ! meiotic cell cycle created_by: jl creation_date: 2014-05-22T14:22:28Z [Term] id: GO:1903047 name: mitotic cell cycle process namespace: biological_process def: "A process that is part of the mitotic cell cycle." [GO_REF:0000060, GOC:mtg_cell_cycle, GOC:TermGenie] subset: gocheck_do_not_annotate is_a: GO:0022402 ! cell cycle process intersection_of: GO:0009987 ! cellular process intersection_of: part_of GO:0000278 ! mitotic cell cycle relationship: part_of GO:0000278 ! mitotic cell cycle created_by: jl creation_date: 2014-05-22T14:22:34Z [Term] id: GO:1903053 name: regulation of extracellular matrix organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030198 ! extracellular matrix organization relationship: regulates GO:0030198 ! extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:41Z [Term] id: GO:1903054 name: negative regulation of extracellular matrix organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "down regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of extracellular matrix organisation" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular matrix organization" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030198 ! extracellular matrix organization relationship: negatively_regulates GO:0030198 ! extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:47Z [Term] id: GO:1903055 name: positive regulation of extracellular matrix organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:22357537] synonym: "activation of extracellular matrix organisation" NARROW [GOC:TermGenie] synonym: "activation of extracellular matrix organization" NARROW [GOC:TermGenie] synonym: "activation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of extracellular matrix organisation" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organization" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular matrix organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030198 ! extracellular matrix organization relationship: positively_regulates GO:0030198 ! extracellular matrix organization created_by: rl creation_date: 2014-05-23T17:15:53Z [Term] id: GO:1903076 name: regulation of protein localization to plasma membrane namespace: biological_process alt_id: GO:0090003 alt_id: GO:1905963 def: "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "regulation of establishment of protein localization in plasma membrane" RELATED [] synonym: "regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] synonym: "regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein targeting to plasma membrane" RELATED [] synonym: "regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072659 ! protein localization to plasma membrane relationship: regulates GO:0072659 ! protein localization to plasma membrane created_by: tb creation_date: 2009-07-10T10:32:44Z [Term] id: GO:1903077 name: negative regulation of protein localization to plasma membrane namespace: biological_process alt_id: GO:0090005 alt_id: GO:1905964 def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "down regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "down regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "down-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "down-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "downregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "downregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "inhibition of protein localisation in plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein targeting to plasma membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein-plasma membrane targeting" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "negative regulation of establishment of protein localization in plasma membrane" RELATED [] synonym: "negative regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "negative regulation of protein localisation in plasma membrane" RELATED [GOC:TermGenie] synonym: "negative regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein targeting to plasma membrane" RELATED [] synonym: "negative regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072659 ! protein localization to plasma membrane relationship: negatively_regulates GO:0072659 ! protein localization to plasma membrane created_by: tb creation_date: 2014-05-29T17:10:16Z [Term] id: GO:1903078 name: positive regulation of protein localization to plasma membrane namespace: biological_process alt_id: GO:0090004 alt_id: GO:1905965 def: "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:11602640] synonym: "activation of protein localisation in plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein targeting to plasma membrane" NARROW [GOC:TermGenie] synonym: "activation of protein-plasma membrane targeting" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of protein localisation in plasma membrane" RELATED [GOC:mah] synonym: "positive regulation of establishment of protein localization to plasma membrane" RELATED [] synonym: "positive regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein targeting to plasma membrane" RELATED [] synonym: "positive regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "up regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "up regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "up-regulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "up-regulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] synonym: "upregulation of protein localisation in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to plasma membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein targeting to plasma membrane" RELATED [GOC:TermGenie] synonym: "upregulation of protein-plasma membrane targeting" RELATED [GOC:TermGenie] is_a: GO:1903076 ! regulation of protein localization to plasma membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072659 ! protein localization to plasma membrane relationship: positively_regulates GO:0072659 ! protein localization to plasma membrane created_by: tb creation_date: 2009-07-10T10:34:17Z [Term] id: GO:1903115 name: regulation of actin filament-based movement namespace: biological_process def: "Any process that modulates the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] is_a: GO:0032970 ! regulation of actin filament-based process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030048 ! actin filament-based movement relationship: regulates GO:0030048 ! actin filament-based movement created_by: al creation_date: 2014-06-12T16:55:57Z [Term] id: GO:1903116 name: positive regulation of actin filament-based movement namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of actin filament-based movement." [GO_REF:0000058, GOC:TermGenie, PMID:24798735] synonym: "activation of actin filament-based movement" NARROW [GOC:TermGenie] synonym: "up regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "up-regulation of actin filament-based movement" EXACT [GOC:TermGenie] synonym: "upregulation of actin filament-based movement" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:1903115 ! regulation of actin filament-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030048 ! actin filament-based movement relationship: positively_regulates GO:0030048 ! actin filament-based movement created_by: al creation_date: 2014-06-12T16:56:04Z [Term] id: GO:1903119 name: protein localization to actin cytoskeleton namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localisation to actin cytoskeleton" EXACT [GOC:TermGenie] synonym: "protein localization in actin cytoskeleton" EXACT [GOC:TermGenie] is_a: GO:0044380 ! protein localization to cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0015629 ! actin cytoskeleton relationship: has_target_end_location GO:0015629 ! actin cytoskeleton created_by: mah creation_date: 2014-06-16T11:27:09Z [Term] id: GO:1903120 name: protein localization to actin filament bundle namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle." [GO_REF:0000087, GOC:TermGenie, PMID:24798735] synonym: "protein localisation in actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localisation to actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localization in actin filament bundle" EXACT [GOC:TermGenie] synonym: "protein localization to actin cable" RELATED [GOC:mah] is_a: GO:1903119 ! protein localization to actin cytoskeleton intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0032432 ! actin filament bundle relationship: has_target_end_location GO:0032432 ! actin filament bundle created_by: mah creation_date: 2014-06-16T11:27:16Z [Term] id: GO:1903131 name: mononuclear cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell." [CL:0000842, GO_REF:0000086, GOC:TermGenie, PMID:24759906] is_a: GO:0002521 ! leukocyte differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0000842 ! mononuclear cell relationship: results_in_acquisition_of_features_of CL:0000842 ! mononuclear cell created_by: cls creation_date: 2014-06-25T15:47:09Z [Term] id: GO:1903224 name: regulation of endodermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035987 ! endodermal cell differentiation relationship: regulates GO:0035987 ! endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:35Z [Term] id: GO:1903225 name: negative regulation of endodermal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "down regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of endoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of endodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035987 ! endodermal cell differentiation relationship: negatively_regulates GO:0035987 ! endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:41Z [Term] id: GO:1903226 name: positive regulation of endodermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23154389] synonym: "activation of endoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of endodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of endodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of endodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1903224 ! regulation of endodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035987 ! endodermal cell differentiation relationship: positively_regulates GO:0035987 ! endodermal cell differentiation created_by: als creation_date: 2014-07-29T13:22:47Z [Term] id: GO:1903251 name: multi-ciliated epithelial cell differentiation namespace: biological_process def: "The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell." [GO_REF:0000086, GOC:sp, GOC:TermGenie, PMID:22231168, PMID:24934224] synonym: "multiciliate cell differentiation" BROAD [] is_a: GO:0030855 ! epithelial cell differentiation intersection_of: GO:0030154 ! cell differentiation intersection_of: results_in_acquisition_of_features_of CL:0005012 ! multi-ciliated epithelial cell relationship: results_in_acquisition_of_features_of CL:0005012 ! multi-ciliated epithelial cell created_by: tb creation_date: 2014-08-05T19:21:21Z [Term] id: GO:1903292 name: protein localization to Golgi membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane." [GO_REF:0000087, GOC:TermGenie, PMID:11378902] synonym: "protein localisation in Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to Golgi membrane" EXACT [GOC:TermGenie] synonym: "protein localization in Golgi membrane" EXACT [GOC:TermGenie] is_a: GO:0034067 ! protein localization to Golgi apparatus is_a: GO:0072657 ! protein localization to membrane intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0000139 ! Golgi membrane relationship: has_target_end_location GO:0000139 ! Golgi membrane created_by: mah creation_date: 2014-08-12T14:22:31Z [Term] id: GO:1903335 name: regulation of vacuolar transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] is_a: GO:0032386 ! regulation of intracellular transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007034 ! vacuolar transport relationship: regulates GO:0007034 ! vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:04Z [Term] id: GO:1903336 name: negative regulation of vacuolar transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "down-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "downregulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "inhibition of vacuolar transport" NARROW [GOC:TermGenie] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007034 ! vacuolar transport relationship: negatively_regulates GO:0007034 ! vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:11Z [Term] id: GO:1903337 name: positive regulation of vacuolar transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vacuolar transport." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "activation of vacuolar transport" NARROW [GOC:TermGenie] synonym: "up regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "up-regulation of vacuolar transport" EXACT [GOC:TermGenie] synonym: "upregulation of vacuolar transport" EXACT [GOC:TermGenie] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:1903335 ! regulation of vacuolar transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007034 ! vacuolar transport relationship: positively_regulates GO:0007034 ! vacuolar transport created_by: vw creation_date: 2014-08-18T13:16:19Z [Term] id: GO:1903353 name: regulation of nucleus organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of nucleus organization." [GO_REF:0000058, GOC:TermGenie, PMID:16943282] synonym: "regulation of nuclear morphology" RELATED [GOC:TermGenie] synonym: "regulation of nuclear organisation" EXACT [GOC:TermGenie] synonym: "regulation of nuclear organization" EXACT [GOC:TermGenie] synonym: "regulation of nuclear organization and biogenesis" RELATED [GOC:TermGenie] synonym: "regulation of nucleus organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006997 ! nucleus organization relationship: regulates GO:0006997 ! nucleus organization created_by: hjd creation_date: 2014-08-20T19:36:16Z [Term] id: GO:1903358 name: regulation of Golgi organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of Golgi organization." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:17562788] synonym: "regulation of Golgi organisation" EXACT [GOC:TermGenie] synonym: "regulation of Golgi organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007030 ! Golgi organization relationship: regulates GO:0007030 ! Golgi organization created_by: als creation_date: 2014-08-21T10:22:22Z [Term] id: GO:1903375 name: facioacoustic ganglion development namespace: biological_process def: "The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure." [GO_REF:0000094, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] synonym: "acoustico-facial VII-VIII ganglion complex development" EXACT [UBERON:0012175] synonym: "acousticofacial ganglion development" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion complex VII-VIII development" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion development" EXACT [GOC:TermGenie] synonym: "facio-acoustic VII-VIII ganglion complex development" EXACT [GOC:TermGenie] is_a: GO:0061550 ! cranial ganglion development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0012175 ! acoustico-facial VII-VIII ganglion complex relationship: results_in_development_of UBERON:0012175 ! acoustico-facial VII-VIII ganglion complex created_by: bf creation_date: 2014-08-26T12:40:36Z [Term] id: GO:1903379 name: regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:0060623 ! regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007076 ! mitotic chromosome condensation relationship: regulates GO:0007076 ! mitotic chromosome condensation created_by: al creation_date: 2014-08-26T13:57:13Z [Term] id: GO:1903380 name: positive regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:9490640] synonym: "activation of mitotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "up regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903379 ! regulation of mitotic chromosome condensation is_a: GO:1905821 ! positive regulation of chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007076 ! mitotic chromosome condensation relationship: positively_regulates GO:0007076 ! mitotic chromosome condensation created_by: al creation_date: 2014-08-26T13:57:29Z [Term] id: GO:1903412 name: response to bile acid namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus." [GO_REF:0000071, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:21757002] is_a: GO:0014070 ! response to organic cyclic compound is_a: GO:0033993 ! response to lipid is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:3098 ! bile acid relationship: has_input CHEBI:3098 ! bile acid created_by: rl creation_date: 2014-09-03T12:45:43Z [Term] id: GO:1903429 name: regulation of cell maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "regulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048469 ! cell maturation relationship: regulates GO:0048469 ! cell maturation created_by: jl creation_date: 2014-09-15T13:31:23Z [Term] id: GO:1903430 name: negative regulation of cell maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "down regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "down regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "down-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "downregulation of cell maturation" EXACT [GOC:TermGenie] synonym: "downregulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "inhibition of cell maturation" NARROW [GOC:TermGenie] synonym: "inhibition of functional differentiation" RELATED [GOC:TermGenie] synonym: "negative regulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048469 ! cell maturation relationship: negatively_regulates GO:0048469 ! cell maturation created_by: jl creation_date: 2014-09-15T13:31:32Z [Term] id: GO:1903431 name: positive regulation of cell maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell maturation." [GO_REF:0000058, GOC:TermGenie, PMID:17459944] synonym: "activation of cell maturation" NARROW [GOC:TermGenie] synonym: "activation of functional differentiation" RELATED [GOC:TermGenie] synonym: "positive regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "up regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "up regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "up-regulation of cell maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of functional differentiation" RELATED [GOC:TermGenie] synonym: "upregulation of cell maturation" EXACT [GOC:TermGenie] synonym: "upregulation of functional differentiation" RELATED [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:1903429 ! regulation of cell maturation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048469 ! cell maturation relationship: positively_regulates GO:0048469 ! cell maturation created_by: jl creation_date: 2014-09-15T13:31:41Z [Term] id: GO:1903441 name: protein localization to ciliary membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane." [GO_REF:0000087, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22139371] synonym: "protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium is_a: GO:0072657 ! protein localization to membrane is_a: GO:1990778 ! protein localization to cell periphery intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0060170 ! ciliary membrane relationship: has_target_end_location GO:0060170 ! ciliary membrane created_by: pr creation_date: 2014-09-16T15:15:39Z [Term] id: GO:1903510 name: mucopolysaccharide metabolic process namespace: biological_process def: "The chemical reactions and pathways involving mucopolysaccharide." [GO_REF:0000068, GOC:dph, GOC:TermGenie, PMID:4236091] synonym: "mucopolysaccharide metabolism" EXACT [GOC:TermGenie] is_a: GO:0030203 ! glycosaminoglycan metabolic process intersection_of: GO:0008152 ! metabolic process intersection_of: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide relationship: has_primary_input_or_output CHEBI:37395 ! mucopolysaccharide created_by: dph creation_date: 2014-10-01T21:55:47Z [Term] id: GO:1903522 name: regulation of blood circulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "regulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0044057 ! regulation of system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008015 ! blood circulation relationship: regulates GO:0008015 ! blood circulation created_by: mr creation_date: 2014-10-06T18:38:56Z [Term] id: GO:1903523 name: negative regulation of blood circulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "down regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "down regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "down-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "downregulation of blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "inhibition of blood circulation" NARROW [GOC:TermGenie] synonym: "inhibition of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "negative regulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008015 ! blood circulation relationship: negatively_regulates GO:0008015 ! blood circulation created_by: mr creation_date: 2014-10-06T18:39:05Z [Term] id: GO:1903524 name: positive regulation of blood circulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood circulation." [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969] synonym: "activation of blood circulation" NARROW [GOC:TermGenie] synonym: "activation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "positive regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "up regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "up-regulation of blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of hemolymph circulation" RELATED [GOC:TermGenie] synonym: "upregulation of blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of hemolymph circulation" RELATED [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008015 ! blood circulation relationship: positively_regulates GO:0008015 ! blood circulation created_by: mr creation_date: 2014-10-06T18:39:13Z [Term] id: GO:1903530 name: regulation of secretion by cell namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0050794 ! regulation of cellular process is_a: GO:0051046 ! regulation of secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032940 ! secretion by cell relationship: regulates GO:0032940 ! secretion by cell created_by: pm creation_date: 2014-10-08T13:24:59Z [Term] id: GO:1903531 name: negative regulation of secretion by cell namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "down regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "downregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "inhibition of cellular secretion" NARROW [GOC:TermGenie] synonym: "inhibition of secretion by cell" NARROW [GOC:TermGenie] synonym: "negative regulation of cellular secretion" EXACT [GOC:TermGenie] is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:0051048 ! negative regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032940 ! secretion by cell relationship: negatively_regulates GO:0032940 ! secretion by cell created_by: pm creation_date: 2014-10-08T13:25:08Z [Term] id: GO:1903532 name: positive regulation of secretion by cell namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secretion by cell." [GO_REF:0000058, GOC:pm, GOC:TermGenie, PMID:12130530] synonym: "activation of cellular secretion" NARROW [GOC:TermGenie] synonym: "activation of secretion by cell" NARROW [GOC:TermGenie] synonym: "positive regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion by cell" EXACT [GOC:TermGenie] synonym: "upregulation of cellular secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion by cell" EXACT [GOC:TermGenie] is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:0051047 ! positive regulation of secretion is_a: GO:1903530 ! regulation of secretion by cell intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032940 ! secretion by cell relationship: positively_regulates GO:0032940 ! secretion by cell created_by: pm creation_date: 2014-10-08T13:25:17Z [Term] id: GO:1903537 name: meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any meiotic cell cycle process that is involved in oocyte maturation." [GO_REF:0000060, GOC:jz, GOC:TermGenie, PMID:25212395] synonym: "meiosis involved in oocyte maturation" BROAD [] is_a: GO:0022412 ! cellular process involved in reproduction in multicellular organism is_a: GO:1903046 ! meiotic cell cycle process intersection_of: GO:1903046 ! meiotic cell cycle process intersection_of: part_of GO:0001556 ! oocyte maturation relationship: part_of GO:0001556 ! oocyte maturation created_by: pr creation_date: 2014-10-09T10:46:14Z [Term] id: GO:1903538 name: regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:jz, GOC:TermGenie, PMID:25212395] synonym: "regulation of meiosis involved in oocyte maturation" BROAD [GOC:TermGenie] is_a: GO:0010564 ! regulation of cell cycle process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation relationship: regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation created_by: pr creation_date: 2014-10-09T10:52:38Z [Term] id: GO:1903541 name: regulation of exosomal secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0017157 ! regulation of exocytosis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990182 ! exosomal secretion relationship: regulates GO:1990182 ! exosomal secretion created_by: pga creation_date: 2014-10-14T11:38:52Z [Term] id: GO:1903542 name: negative regulation of exosomal secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "down regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "down-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "down-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "downregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "downregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "downregulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "inhibition of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "inhibition of exosomal secretion" NARROW [GOC:TermGenie] synonym: "inhibition of exosomal secretory pathway" NARROW [GOC:TermGenie] synonym: "inhibition of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] synonym: "inhibition of secretion of exosome" NARROW [GOC:TermGenie] synonym: "negative regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "negative regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "negative regulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0045920 ! negative regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990182 ! exosomal secretion relationship: negatively_regulates GO:1990182 ! exosomal secretion created_by: pga creation_date: 2014-10-14T11:39:02Z [Term] id: GO:1903543 name: positive regulation of exosomal secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of exosomal secretion." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "activation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "activation of exosomal secretion" NARROW [GOC:TermGenie] synonym: "activation of exosomal secretory pathway" NARROW [GOC:TermGenie] synonym: "activation of extracellular vesicular exosome secretion" NARROW [GOC:TermGenie] synonym: "activation of secretion of exosome" NARROW [GOC:TermGenie] synonym: "positive regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "positive regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "positive regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "positive regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "up regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "up-regulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "up-regulation of secretion of exosome" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal protein secretion" NARROW [GOC:TermGenie] synonym: "upregulation of exosomal secretion" EXACT [GOC:TermGenie] synonym: "upregulation of exosomal secretory pathway" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome secretion" EXACT [GOC:TermGenie] synonym: "upregulation of secretion of exosome" EXACT [GOC:TermGenie] is_a: GO:0044089 ! positive regulation of cellular component biogenesis is_a: GO:0045921 ! positive regulation of exocytosis is_a: GO:1903541 ! regulation of exosomal secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990182 ! exosomal secretion relationship: positively_regulates GO:1990182 ! exosomal secretion created_by: pga creation_date: 2014-10-14T11:39:10Z [Term] id: GO:1903551 name: regulation of extracellular exosome assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902115 ! regulation of organelle assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071971 ! extracellular exosome assembly relationship: regulates GO:0071971 ! extracellular exosome assembly created_by: pga creation_date: 2014-10-20T15:37:25Z [Term] id: GO:1903552 name: negative regulation of extracellular exosome assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "down regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "downregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "inhibition of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] synonym: "negative regulation of extracellular vesicular exosome assembly" EXACT [GOC:vesicles] is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071971 ! extracellular exosome assembly relationship: negatively_regulates GO:0071971 ! extracellular exosome assembly created_by: pga creation_date: 2014-10-20T15:37:33Z [Term] id: GO:1903553 name: positive regulation of extracellular exosome assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly." [GO_REF:0000058, GOC:TermGenie, PMID:24105262] synonym: "activation of extracellular vesicular exosome assembly" NARROW [GOC:TermGenie] synonym: "positive regulation of extracellular vesicular exosome assembly" RELATED [GOC:vesicles] synonym: "up regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] synonym: "upregulation of extracellular vesicular exosome assembly" EXACT [GOC:TermGenie] is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1903551 ! regulation of extracellular exosome assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071971 ! extracellular exosome assembly relationship: positively_regulates GO:0071971 ! extracellular exosome assembly created_by: pga creation_date: 2014-10-20T15:37:42Z [Term] id: GO:1903561 name: extracellular vesicle namespace: cellular_component def: "Any vesicle that is part of the extracellular region." [GO_REF:0000064, GOC:pm, GOC:TermGenie, PMID:24769233] synonym: "microparticle" RELATED [GOC:vesicles] is_a: GO:0031982 ! vesicle is_a: GO:0065010 ! extracellular membrane-bounded organelle intersection_of: GO:0031982 ! vesicle intersection_of: part_of GO:0005576 ! extracellular region created_by: jl creation_date: 2014-10-22T14:26:11Z [Term] id: GO:1903564 name: regulation of protein localization to cilium namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061512 ! protein localization to cilium relationship: regulates GO:0061512 ! protein localization to cilium created_by: krc creation_date: 2014-10-24T20:58:11Z [Term] id: GO:1903565 name: negative regulation of protein localization to cilium namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "inhibition of protein localization to cilium" NARROW [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061512 ! protein localization to cilium relationship: negatively_regulates GO:0061512 ! protein localization to cilium created_by: krc creation_date: 2014-10-24T20:58:20Z [Term] id: GO:1903566 name: positive regulation of protein localization to cilium namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cilium." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "activation of protein localization to cilium" NARROW [GOC:TermGenie] synonym: "up regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cilium" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cilium" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061512 ! protein localization to cilium relationship: positively_regulates GO:0061512 ! protein localization to cilium created_by: krc creation_date: 2014-10-24T20:58:28Z [Term] id: GO:1903567 name: regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903564 ! regulation of protein localization to cilium is_a: GO:1904375 ! regulation of protein localization to cell periphery is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1903441 ! protein localization to ciliary membrane relationship: regulates GO:1903441 ! protein localization to ciliary membrane created_by: krc creation_date: 2014-10-24T21:32:51Z [Term] id: GO:1903568 name: negative regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "down regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in ciliary membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to ciliary membrane" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903565 ! negative regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1905476 ! negative regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1903441 ! protein localization to ciliary membrane relationship: negatively_regulates GO:1903441 ! protein localization to ciliary membrane created_by: krc creation_date: 2014-10-24T21:32:59Z [Term] id: GO:1903569 name: positive regulation of protein localization to ciliary membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:22072986] synonym: "activation of protein localisation in ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in ciliary membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to ciliary membrane" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in ciliary membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to ciliary membrane" EXACT [GOC:TermGenie] is_a: GO:1903566 ! positive regulation of protein localization to cilium is_a: GO:1903567 ! regulation of protein localization to ciliary membrane is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1905477 ! positive regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1903441 ! protein localization to ciliary membrane relationship: positively_regulates GO:1903441 ! protein localization to ciliary membrane created_by: krc creation_date: 2014-10-24T21:33:08Z [Term] id: GO:1903624 name: regulation of DNA catabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "regulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031329 ! regulation of cellular catabolic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0006308 ! DNA catabolic process relationship: regulates GO:0006308 ! DNA catabolic process created_by: sl creation_date: 2014-11-19T22:36:35Z [Term] id: GO:1903625 name: negative regulation of DNA catabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "down regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "downregulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "inhibition of DNA breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of DNA catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of DNA degradation" NARROW [GOC:TermGenie] synonym: "negative regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031330 ! negative regulation of cellular catabolic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006308 ! DNA catabolic process relationship: negatively_regulates GO:0006308 ! DNA catabolic process created_by: sl creation_date: 2014-11-19T22:36:43Z [Term] id: GO:1903626 name: positive regulation of DNA catabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA catabolic process." [GO_REF:0000058, GOC:TermGenie, PMID:2001740] synonym: "activation of DNA breakdown" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolic process" NARROW [GOC:TermGenie] synonym: "activation of DNA catabolism" NARROW [GOC:TermGenie] synonym: "activation of DNA degradation" NARROW [GOC:TermGenie] synonym: "positive regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "up regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of DNA degradation" EXACT [GOC:TermGenie] synonym: "upregulation of DNA breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of DNA catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of DNA degradation" EXACT [GOC:TermGenie] is_a: GO:0031331 ! positive regulation of cellular catabolic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:1903624 ! regulation of DNA catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006308 ! DNA catabolic process relationship: positively_regulates GO:0006308 ! DNA catabolic process created_by: sl creation_date: 2014-11-19T22:36:51Z [Term] id: GO:1903697 name: negative regulation of microvillus assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "down regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "down regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "downregulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of microvillus assembly" NARROW [GOC:TermGenie] synonym: "inhibition of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of microvillus biogenesis" RELATED [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030033 ! microvillus assembly relationship: negatively_regulates GO:0030033 ! microvillus assembly created_by: als creation_date: 2014-12-03T11:45:08Z [Term] id: GO:1903698 name: positive regulation of microvillus assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of microvillus assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:22797597] synonym: "activation of microvillus assembly" NARROW [GOC:TermGenie] synonym: "activation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "up regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of microvillus biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of microvillus assembly" EXACT [GOC:TermGenie] synonym: "upregulation of microvillus biogenesis" RELATED [GOC:TermGenie] is_a: GO:0032534 ! regulation of microvillus assembly is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030033 ! microvillus assembly relationship: positively_regulates GO:0030033 ! microvillus assembly created_by: als creation_date: 2014-12-03T11:45:17Z [Term] id: GO:1903701 name: substantia propria of cornea development namespace: biological_process def: "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12556382] synonym: "corneal stroma development" EXACT [GOC:TermGenie] synonym: "stroma of cornea development" EXACT [GOC:TermGenie] synonym: "substantia propria development" RELATED [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001777 ! substantia propria of cornea relationship: results_in_development_of UBERON:0001777 ! substantia propria of cornea created_by: cls creation_date: 2014-12-03T13:12:09Z [Term] id: GO:1903702 name: esophagus development namespace: biological_process def: "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0-683-40008-8] synonym: "esophageal development" EXACT [MGI:csmith] synonym: "gullet development" EXACT [GOC:TermGenie] synonym: "oesophagus development" EXACT [GOC:TermGenie] is_a: GO:0048513 ! animal organ development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001043 ! esophagus relationship: results_in_development_of UBERON:0001043 ! esophagus created_by: cls creation_date: 2014-12-03T14:41:30Z [Term] id: GO:1903706 name: regulation of hemopoiesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002682 ! regulation of immune system process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030097 ! hemopoiesis relationship: regulates GO:0030097 ! hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:13Z [Term] id: GO:1903707 name: negative regulation of hemopoiesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "down regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "down-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "down-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "downregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "downregulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "inhibition of blood cell biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of blood cell formation" NARROW [GOC:TermGenie] synonym: "inhibition of haemopoiesis" NARROW [GOC:TermGenie] synonym: "inhibition of hematopoiesis" NARROW [GOC:TermGenie] synonym: "inhibition of hemopoiesis" NARROW [GOC:TermGenie] synonym: "negative regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "negative regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "negative regulation of hematopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002683 ! negative regulation of immune system process is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030097 ! hemopoiesis relationship: negatively_regulates GO:0030097 ! hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:21Z [Term] id: GO:1903708 name: positive regulation of hemopoiesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hemopoiesis." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:20080761] comment: An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. synonym: "activation of blood cell biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of blood cell formation" NARROW [GOC:TermGenie] synonym: "activation of haemopoiesis" NARROW [GOC:TermGenie] synonym: "activation of hematopoiesis" NARROW [GOC:TermGenie] synonym: "activation of hemopoiesis" NARROW [GOC:TermGenie] synonym: "positive regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "positive regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "positive regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "up-regulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "up-regulation of hemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of blood cell formation" EXACT [GOC:TermGenie] synonym: "upregulation of haemopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hematopoiesis" EXACT [GOC:TermGenie] synonym: "upregulation of hemopoiesis" EXACT [GOC:TermGenie] is_a: GO:0002684 ! positive regulation of immune system process is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1903706 ! regulation of hemopoiesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030097 ! hemopoiesis relationship: positively_regulates GO:0030097 ! hemopoiesis created_by: pad creation_date: 2014-12-04T15:34:30Z [Term] id: GO:1903709 name: uterine gland development namespace: biological_process def: "The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:23619340] synonym: "endometrial gland development" EXACT [GOC:TermGenie] synonym: "endometrium gland development" EXACT [GOC:TermGenie] synonym: "glandulae uterinae development" RELATED [GOC:TermGenie] synonym: "glandular part of endometrium development" RELATED [GOC:TermGenie] synonym: "set of uterine glands development" RELATED [GOC:TermGenie] synonym: "uterine glands development" EXACT [GOC:TermGenie] synonym: "uterine glands set development" EXACT [GOC:TermGenie] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002451 ! endometrial gland relationship: results_in_development_of UBERON:0002451 ! endometrial gland created_by: cls creation_date: 2014-12-04T18:57:21Z [Term] id: GO:1903729 name: regulation of plasma membrane organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of plasma membrane organization." [GO_REF:0000058, GOC:TermGenie, PMID:24514900] synonym: "regulation of plasma membrane organisation" EXACT [GOC:TermGenie] synonym: "regulation of plasma membrane organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0051128 ! regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007009 ! plasma membrane organization relationship: regulates GO:0007009 ! plasma membrane organization created_by: al creation_date: 2014-12-10T18:59:44Z [Term] id: GO:1903778 name: protein localization to vacuolar membrane namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane." [GO_REF:0000087, GOC:TermGenie, PMID:25378562] synonym: "protein localisation in vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localisation to vacuolar membrane" EXACT [GOC:TermGenie] synonym: "protein localization in vacuolar membrane" EXACT [GOC:TermGenie] is_a: GO:0072657 ! protein localization to membrane is_a: GO:0072665 ! protein localization to vacuole intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005774 ! vacuolar membrane relationship: has_target_end_location GO:0005774 ! vacuolar membrane created_by: mah creation_date: 2015-01-07T13:15:54Z [Term] id: GO:1903779 name: regulation of cardiac conduction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] is_a: GO:0008016 ! regulation of heart contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061337 ! cardiac conduction relationship: regulates GO:0061337 ! cardiac conduction created_by: rph creation_date: 2015-01-07T13:20:11Z [Term] id: GO:1903780 name: negative regulation of cardiac conduction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "down regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac conduction" NARROW [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061337 ! cardiac conduction relationship: negatively_regulates GO:0061337 ! cardiac conduction created_by: rph creation_date: 2015-01-07T13:20:20Z [Term] id: GO:1903781 name: positive regulation of cardiac conduction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac conduction." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:rph, GOC:TermGenie, PMID:12967627] synonym: "activation of cardiac conduction" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac conduction" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac conduction" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1903779 ! regulation of cardiac conduction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061337 ! cardiac conduction relationship: positively_regulates GO:0061337 ! cardiac conduction created_by: rph creation_date: 2015-01-07T13:20:28Z [Term] id: GO:1903789 name: regulation of amino acid transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:16115814] synonym: "regulation of amino acid membrane transport" EXACT [GOC:TermGenie] is_a: GO:0034762 ! regulation of transmembrane transport is_a: GO:0051955 ! regulation of amino acid transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003333 ! amino acid transmembrane transport relationship: regulates GO:0003333 ! amino acid transmembrane transport created_by: al creation_date: 2015-01-08T17:42:18Z [Term] id: GO:1903795 name: regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034762 ! regulation of transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098661 ! inorganic anion transmembrane transport relationship: regulates GO:0098661 ! inorganic anion transmembrane transport created_by: sl creation_date: 2015-01-14T21:44:49Z [Term] id: GO:1903796 name: negative regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "down regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "down-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "downregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "inhibition of inorganic anion membrane transport" NARROW [GOC:TermGenie] synonym: "inhibition of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] synonym: "inhibition of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] synonym: "negative regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "negative regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034763 ! negative regulation of transmembrane transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport relationship: negatively_regulates GO:0098661 ! inorganic anion transmembrane transport created_by: sl creation_date: 2015-01-14T21:44:59Z [Term] id: GO:1903797 name: positive regulation of inorganic anion transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:11336802] synonym: "activation of inorganic anion membrane transport" NARROW [GOC:TermGenie] synonym: "activation of inorganic anion transmembrane transport" NARROW [GOC:TermGenie] synonym: "activation of transmembrane inorganic anion transport" NARROW [GOC:TermGenie] synonym: "positive regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "positive regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "up regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "up-regulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] synonym: "upregulation of inorganic anion membrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of inorganic anion transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of transmembrane inorganic anion transport" EXACT [GOC:TermGenie] is_a: GO:0034764 ! positive regulation of transmembrane transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098661 ! inorganic anion transmembrane transport relationship: positively_regulates GO:0098661 ! inorganic anion transmembrane transport created_by: sl creation_date: 2015-01-14T21:45:08Z [Term] id: GO:1903825 name: organic acid transmembrane transport namespace: biological_process def: "The process in which an organic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie] is_a: GO:0015849 ! organic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:64709 ! organic acid intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: vw creation_date: 2015-01-20T10:20:58Z [Term] id: GO:1903828 name: negative regulation of protein localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "down regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "inhibition of cellular protein localisation" NARROW [GOC:TermGenie] synonym: "inhibition of cellular protein localization" NARROW [GOC:TermGenie] synonym: "negative regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of cellular protein localization" EXACT [] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048523 ! negative regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008104 ! protein localization relationship: negatively_regulates GO:0008104 ! protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:24Z [Term] id: GO:1903829 name: positive regulation of protein localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of a protein localization." [GO_REF:0000058, GOC:TermGenie, GOC:vw] synonym: "positive regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of cellular protein localization" EXACT [] synonym: "up regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of cellular protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of cellular protein localization" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization is_a: GO:0048522 ! positive regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008104 ! protein localization relationship: positively_regulates GO:0008104 ! protein localization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22021" xsd:anyURI created_by: jl creation_date: 2015-01-20T14:32:33Z [Term] id: GO:1903847 name: regulation of aorta morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035909 ! aorta morphogenesis relationship: regulates GO:0035909 ! aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:00:51Z [Term] id: GO:1903848 name: negative regulation of aorta morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "down regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of aorta morphogenesis" NARROW [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905652 ! negative regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035909 ! aorta morphogenesis relationship: negatively_regulates GO:0035909 ! aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:01:01Z [Term] id: GO:1903849 name: positive regulation of aorta morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22269326] synonym: "activation of aorta morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of aorta morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of aorta morphogenesis" EXACT [GOC:TermGenie] is_a: GO:1903847 ! regulation of aorta morphogenesis is_a: GO:1905653 ! positive regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035909 ! aorta morphogenesis relationship: positively_regulates GO:0035909 ! aorta morphogenesis created_by: rph creation_date: 2015-01-23T14:01:09Z [Term] id: GO:1903867 name: extraembryonic membrane development namespace: biological_process def: "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, ISBN:0073040584] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0005631 ! extraembryonic membrane relationship: results_in_development_of UBERON:0005631 ! extraembryonic membrane created_by: cjm creation_date: 2015-02-05T00:42:16Z [Term] id: GO:1903903 name: regulation of establishment of T cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:2000114 ! regulation of establishment of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001768 ! establishment of T cell polarity relationship: regulates GO:0001768 ! establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:21Z [Term] id: GO:1903904 name: negative regulation of establishment of T cell polarity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "down regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "down-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "down-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "downregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "downregulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "inhibition of establishment of T cell polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T-cell polarity" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "inhibition of T cell polarization" NARROW [GOC:TermGenie] synonym: "inhibition of T lymphocyte polarization" NARROW [GOC:TermGenie] synonym: "inhibition of T-cell polarization" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "negative regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "negative regulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050868 ! negative regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001768 ! establishment of T cell polarity relationship: negatively_regulates GO:0001768 ! establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:30Z [Term] id: GO:1903905 name: positive regulation of establishment of T cell polarity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:23575248] synonym: "activation of establishment of T cell polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T-cell polarity" NARROW [GOC:TermGenie] synonym: "activation of establishment of T-lymphocyte polarity" NARROW [GOC:TermGenie] synonym: "activation of T cell polarization" NARROW [GOC:TermGenie] synonym: "activation of T lymphocyte polarization" NARROW [GOC:TermGenie] synonym: "activation of T-cell polarization" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "positive regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "positive regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "up-regulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "up-regulation of T-cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-cell polarity" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of T-lymphocyte polarity" EXACT [GOC:TermGenie] synonym: "upregulation of T cell polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T lymphocyte polarization" EXACT [GOC:TermGenie] synonym: "upregulation of T-cell polarization" EXACT [GOC:TermGenie] is_a: GO:0050870 ! positive regulation of T cell activation is_a: GO:1903903 ! regulation of establishment of T cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001768 ! establishment of T cell polarity relationship: positively_regulates GO:0001768 ! establishment of T cell polarity created_by: als creation_date: 2015-02-09T10:50:40Z [Term] id: GO:1903941 name: negative regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "down regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "down-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "downregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "inhibition of respiratory gaseous exchange" NARROW [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051241 ! negative regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: negatively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system created_by: sl creation_date: 2015-02-17T20:26:24Z [Term] id: GO:1903942 name: positive regulation of respiratory gaseous exchange namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange." [GO_REF:0000058, GOC:TermGenie, PMID:22819705] synonym: "activation of respiratory gaseous exchange" NARROW [GOC:TermGenie] synonym: "up regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "up-regulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] synonym: "upregulation of respiratory gaseous exchange" EXACT [GOC:TermGenie] is_a: GO:0043576 ! regulation of respiratory gaseous exchange is_a: GO:0051240 ! positive regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: positively_regulates GO:0007585 ! respiratory gaseous exchange by respiratory system created_by: sl creation_date: 2015-02-17T20:26:35Z [Term] id: GO:1903943 name: regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097284 ! hepatocyte apoptotic process relationship: regulates GO:0097284 ! hepatocyte apoptotic process created_by: sl creation_date: 2015-02-19T12:54:40Z [Term] id: GO:1903944 name: negative regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "down regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of hepatocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097284 ! hepatocyte apoptotic process relationship: negatively_regulates GO:0097284 ! hepatocyte apoptotic process created_by: sl creation_date: 2015-02-19T12:54:50Z [Term] id: GO:1903945 name: positive regulation of hepatocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:8649852] synonym: "activation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of hepatocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of hepatocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of hepatocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1903943 ! regulation of hepatocyte apoptotic process is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097284 ! hepatocyte apoptotic process relationship: positively_regulates GO:0097284 ! hepatocyte apoptotic process created_by: sl creation_date: 2015-02-19T12:54:59Z [Term] id: GO:1903950 name: negative regulation of AV node cell action potential namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "down regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "downregulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "inhibition of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "inhibition of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "inhibition of AV node cell action potential" NARROW [GOC:TermGenie] synonym: "negative regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "negative regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0086016 ! AV node cell action potential relationship: negatively_regulates GO:0086016 ! AV node cell action potential created_by: nc creation_date: 2015-02-20T14:59:41Z [Term] id: GO:1903951 name: positive regulation of AV node cell action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of AV node cell action potential." [GO_REF:0000058, GOC:BHF, GOC:mtg_cardiac_conduct_nov11, GOC:nc, GOC:TermGenie, PMID:25281747] synonym: "activation of atrioventricular node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "activation of AV node cardiac muscle cell action potential" NARROW [GOC:TermGenie] synonym: "activation of AV node cell action potential" NARROW [GOC:TermGenie] synonym: "positive regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "positive regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of AV node cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of atrioventricular node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cardiac muscle cell action potential" EXACT [GOC:TermGenie] synonym: "upregulation of AV node cell action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0098904 ! regulation of AV node cell action potential intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0086016 ! AV node cell action potential relationship: positively_regulates GO:0086016 ! AV node cell action potential created_by: nc creation_date: 2015-02-20T14:59:50Z [Term] id: GO:1903975 name: regulation of glial cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008347 ! glial cell migration relationship: regulates GO:0008347 ! glial cell migration created_by: nc creation_date: 2015-03-02T15:13:31Z [Term] id: GO:1903976 name: negative regulation of glial cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "down regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of glia cell migration" NARROW [GOC:TermGenie] synonym: "inhibition of glial cell migration" NARROW [GOC:TermGenie] synonym: "negative regulation of glia cell migration" EXACT [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008347 ! glial cell migration relationship: negatively_regulates GO:0008347 ! glial cell migration created_by: nc creation_date: 2015-03-02T15:13:38Z [Term] id: GO:1903977 name: positive regulation of glial cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of glial cell migration." [GO_REF:0000058, GOC:BHF, GOC:nc, GOC:TermGenie, PMID:19100238] synonym: "activation of glia cell migration" NARROW [GOC:TermGenie] synonym: "activation of glial cell migration" NARROW [GOC:TermGenie] synonym: "positive regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of glial cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glia cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of glial cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1903975 ! regulation of glial cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008347 ! glial cell migration relationship: positively_regulates GO:0008347 ! glial cell migration created_by: nc creation_date: 2015-03-02T15:13:43Z [Term] id: GO:1904014 name: response to serotonin namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:1505525] is_a: GO:1901698 ! response to nitrogen compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:350546 ! serotonin(1+) relationship: has_input CHEBI:350546 ! serotonin(1+) created_by: sl creation_date: 2015-03-06T19:33:54Z [Term] id: GO:1904018 name: positive regulation of vasculature development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vasculature development." [GO_REF:0000058, GOC:TermGenie, PMID:21472453] synonym: "activation of vascular system development" RELATED [GOC:TermGenie] synonym: "activation of vasculature development" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular system development" RELATED [GOC:TermGenie] synonym: "up-regulation of vasculature development" EXACT [GOC:TermGenie] synonym: "upregulation of vascular system development" RELATED [GOC:TermGenie] synonym: "upregulation of vasculature development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901342 ! regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001944 ! vasculature development relationship: positively_regulates GO:0001944 ! vasculature development created_by: sl creation_date: 2015-03-06T22:17:04Z [Term] id: GO:1904019 name: epithelial cell apoptotic process namespace: biological_process def: "Any apoptotic process in an epithelial cell." [GO_REF:0000085, GOC:TermGenie, PMID:19137015] synonym: "epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000066 ! epithelial cell relationship: occurs_in CL:0000066 ! epithelial cell property_value: RO:0002161 NCBITaxon:33090 property_value: RO:0002161 NCBITaxon_Union:0000023 created_by: sl creation_date: 2015-03-06T22:27:17Z [Term] id: GO:1904026 name: regulation of collagen fibril organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "regulation of collagen fibrillogenesis" RELATED [] synonym: "regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902903 ! regulation of supramolecular fiber organization is_a: GO:1903053 ! regulation of extracellular matrix organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030199 ! collagen fibril organization relationship: regulates GO:0030199 ! collagen fibril organization created_by: ae creation_date: 2015-03-12T12:36:52Z [Term] id: GO:1904027 name: negative regulation of collagen fibril organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "down regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "down-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "downregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "downregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "inhibition of collagen fibril organisation" NARROW [GOC:TermGenie] synonym: "inhibition of collagen fibril organization" NARROW [GOC:TermGenie] synonym: "inhibition of fibrillar collagen organization" NARROW [GOC:TermGenie] synonym: "negative regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902904 ! negative regulation of supramolecular fiber organization is_a: GO:1903054 ! negative regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030199 ! collagen fibril organization relationship: negatively_regulates GO:0030199 ! collagen fibril organization created_by: ae creation_date: 2015-03-12T12:36:59Z [Term] id: GO:1904028 name: positive regulation of collagen fibril organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of collagen fibril organization." [GO_REF:0000058, GOC:TermGenie, PMID:25451920] synonym: "activation of collagen fibril organisation" NARROW [GOC:TermGenie] synonym: "activation of collagen fibril organization" NARROW [GOC:TermGenie] synonym: "activation of fibrillar collagen organization" NARROW [GOC:TermGenie] synonym: "positive regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "up-regulation of fibrillar collagen organization" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organisation" EXACT [GOC:TermGenie] synonym: "upregulation of collagen fibril organization" EXACT [GOC:TermGenie] synonym: "upregulation of fibrillar collagen organization" EXACT [GOC:TermGenie] is_a: GO:1902905 ! positive regulation of supramolecular fiber organization is_a: GO:1903055 ! positive regulation of extracellular matrix organization is_a: GO:1904026 ! regulation of collagen fibril organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030199 ! collagen fibril organization relationship: positively_regulates GO:0030199 ! collagen fibril organization created_by: ae creation_date: 2015-03-12T12:37:06Z [Term] id: GO:1904035 name: regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904019 ! epithelial cell apoptotic process relationship: regulates GO:1904019 ! epithelial cell apoptotic process created_by: sl creation_date: 2015-03-13T22:05:41Z [Term] id: GO:1904036 name: negative regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "down regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904019 ! epithelial cell apoptotic process relationship: negatively_regulates GO:1904019 ! epithelial cell apoptotic process created_by: sl creation_date: 2015-03-13T22:05:47Z [Term] id: GO:1904037 name: positive regulation of epithelial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:19137015] synonym: "activation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epitheliocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epithelial cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epitheliocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epitheliocyte apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904019 ! epithelial cell apoptotic process relationship: positively_regulates GO:1904019 ! epithelial cell apoptotic process created_by: sl creation_date: 2015-03-13T22:05:53Z [Term] id: GO:1904054 name: regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990705 ! cholangiocyte proliferation relationship: regulates GO:1990705 ! cholangiocyte proliferation created_by: sl creation_date: 2015-03-18T17:56:14Z [Term] id: GO:1904055 name: negative regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "down regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of cholangiocyte proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of hepatoblast proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990705 ! cholangiocyte proliferation relationship: negatively_regulates GO:1990705 ! cholangiocyte proliferation created_by: sl creation_date: 2015-03-18T17:56:20Z [Term] id: GO:1904056 name: positive regulation of cholangiocyte proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24434010] synonym: "activation of cholangiocyte proliferation" NARROW [GOC:TermGenie] synonym: "activation of hepatoblast proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of hepatoblast proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of hepatoblast proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904054 ! regulation of cholangiocyte proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990705 ! cholangiocyte proliferation relationship: positively_regulates GO:1990705 ! cholangiocyte proliferation created_by: sl creation_date: 2015-03-18T17:56:26Z [Term] id: GO:1904057 name: negative regulation of sensory perception of pain namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "down regulation of nociception" EXACT [GOC:TermGenie] synonym: "down regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "down regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "down-regulation of nociception" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "down-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "downregulation of nociception" EXACT [GOC:TermGenie] synonym: "downregulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "downregulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "inhibition of nociception" NARROW [GOC:TermGenie] synonym: "inhibition of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "inhibition of sensory perception of pain" NARROW [GOC:TermGenie] synonym: "negative regulation of nociception" EXACT [GOC:TermGenie] synonym: "negative regulation of perception of physiological pain" NARROW [GOC:TermGenie] is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019233 ! sensory perception of pain relationship: negatively_regulates GO:0019233 ! sensory perception of pain created_by: sl creation_date: 2015-03-18T20:33:57Z [Term] id: GO:1904058 name: positive regulation of sensory perception of pain namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sensory perception of pain." [GO_REF:0000058, GOC:TermGenie, PMID:17167094] synonym: "activation of nociception" NARROW [GOC:TermGenie] synonym: "activation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "activation of sensory perception of pain" NARROW [GOC:TermGenie] synonym: "positive regulation of nociception" EXACT [GOC:TermGenie] synonym: "positive regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up regulation of nociception" EXACT [GOC:TermGenie] synonym: "up regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "up-regulation of nociception" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "up-regulation of sensory perception of pain" EXACT [GOC:TermGenie] synonym: "upregulation of nociception" EXACT [GOC:TermGenie] synonym: "upregulation of perception of physiological pain" NARROW [GOC:TermGenie] synonym: "upregulation of sensory perception of pain" EXACT [GOC:TermGenie] is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0051930 ! regulation of sensory perception of pain intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019233 ! sensory perception of pain relationship: positively_regulates GO:0019233 ! sensory perception of pain created_by: sl creation_date: 2015-03-18T20:34:03Z [Term] id: GO:1904062 name: regulation of monoatomic cation transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "regulation of cation transmembrane transport" BROAD [] is_a: GO:0034765 ! regulation of monoatomic ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098655 ! monoatomic cation transmembrane transport relationship: regulates GO:0098655 ! monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:43Z [Term] id: GO:1904063 name: negative regulation of cation transmembrane transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "down regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "down-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "downregulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "inhibition of cation transmembrane transport" NARROW [GOC:TermGenie] is_a: GO:0034766 ! negative regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098655 ! monoatomic cation transmembrane transport relationship: negatively_regulates GO:0098655 ! monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:50Z [Term] id: GO:1904064 name: positive regulation of cation transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cation transmembrane transport." [GO_REF:0000058, GOC:TermGenie, PMID:15304482] synonym: "activation of cation transmembrane transport" NARROW [GOC:TermGenie] synonym: "up regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "up-regulation of cation transmembrane transport" EXACT [GOC:TermGenie] synonym: "upregulation of cation transmembrane transport" EXACT [GOC:TermGenie] is_a: GO:0034767 ! positive regulation of monoatomic ion transmembrane transport is_a: GO:1904062 ! regulation of monoatomic cation transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098655 ! monoatomic cation transmembrane transport relationship: positively_regulates GO:0098655 ! monoatomic cation transmembrane transport created_by: sl creation_date: 2015-03-18T21:11:55Z [Term] id: GO:1904073 name: regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0048638 ! regulation of developmental growth intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001834 ! trophectodermal cell proliferation relationship: regulates GO:0001834 ! trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:55:56Z [Term] id: GO:1904074 name: negative regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "down regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of trophectoderm cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of trophectodermal cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001834 ! trophectodermal cell proliferation relationship: negatively_regulates GO:0001834 ! trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:56:02Z [Term] id: GO:1904075 name: positive regulation of trophectodermal cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24508636] synonym: "activation of trophectoderm cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of trophectodermal cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectoderm cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of trophectodermal cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:1904073 ! regulation of trophectodermal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001834 ! trophectodermal cell proliferation relationship: positively_regulates GO:0001834 ! trophectodermal cell proliferation created_by: tb creation_date: 2015-03-20T16:56:08Z [Term] id: GO:1904106 name: protein localization to microvillus namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a microvillus." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:25335890] synonym: "protein localisation in microvillus" EXACT [GOC:TermGenie] synonym: "protein localisation to microvillus" EXACT [GOC:TermGenie] synonym: "protein localization in microvillus" EXACT [GOC:TermGenie] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005902 ! microvillus relationship: has_target_end_location GO:0005902 ! microvillus created_by: kmv creation_date: 2015-04-01T18:14:41Z [Term] id: GO:1904115 name: axon cytoplasm namespace: cellular_component def: "Any cytoplasm that is part of a axon." [GO_REF:0000064, GOC:TermGenie, PMID:18667152] synonym: "axoplasm" EXACT [] is_a: GO:0120111 ! neuron projection cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of GO:0030424 ! axon relationship: part_of GO:0030424 ! axon property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/14472" xsd:anyURI created_by: sl creation_date: 2015-04-06T18:13:14Z [Term] id: GO:1904118 name: regulation of otic vesicle morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071600 ! otic vesicle morphogenesis relationship: regulates GO:0071600 ! otic vesicle morphogenesis created_by: pga creation_date: 2015-04-07T14:00:56Z [Term] id: GO:1904119 name: negative regulation of otic vesicle morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] synonym: "down regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of otic vesicle morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0110111 ! negative regulation of animal organ morphogenesis is_a: GO:1904118 ! regulation of otic vesicle morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071600 ! otic vesicle morphogenesis relationship: negatively_regulates GO:0071600 ! otic vesicle morphogenesis created_by: pga creation_date: 2015-04-07T14:01:02Z [Term] id: GO:1904120 name: positive regulation of otic vesicle morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:25677106] synonym: "activation of otic vesicle morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of otic vesicle morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0110110 ! positive regulation of animal organ morphogenesis is_a: GO:1904118 ! regulation of otic vesicle morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071600 ! otic vesicle morphogenesis relationship: positively_regulates GO:0071600 ! otic vesicle morphogenesis created_by: pga creation_date: 2015-04-07T14:01:08Z [Term] id: GO:1904145 name: negative regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "down regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "down-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "downregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "inhibition of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051447 ! negative regulation of meiotic cell cycle is_a: GO:1900194 ! negative regulation of oocyte maturation is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation relationship: negatively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation created_by: tb creation_date: 2015-04-14T15:59:22Z [Term] id: GO:1904146 name: positive regulation of meiotic cell cycle process involved in oocyte maturation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." [GO_REF:0000058, GOC:TermGenie, PMID:22674394] synonym: "activation of meiotic cell cycle process involved in oocyte maturation" NARROW [GOC:TermGenie] synonym: "up regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "up-regulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] synonym: "upregulation of meiotic cell cycle process involved in oocyte maturation" EXACT [GOC:TermGenie] is_a: GO:0051446 ! positive regulation of meiotic cell cycle is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1903538 ! regulation of meiotic cell cycle process involved in oocyte maturation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation relationship: positively_regulates GO:1903537 ! meiotic cell cycle process involved in oocyte maturation created_by: tb creation_date: 2015-04-14T15:59:28Z [Term] id: GO:1904170 name: regulation of bleb assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032060 ! bleb assembly relationship: regulates GO:0032060 ! bleb assembly created_by: als creation_date: 2015-04-23T09:32:19Z [Term] id: GO:1904171 name: negative regulation of bleb assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "down regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "down-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "downregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "inhibition of bleb assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cell blebbing" NARROW [GOC:TermGenie] synonym: "negative regulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0032060 ! bleb assembly relationship: negatively_regulates GO:0032060 ! bleb assembly created_by: als creation_date: 2015-04-23T09:32:25Z [Term] id: GO:1904172 name: positive regulation of bleb assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bleb assembly." [GO_REF:0000058, GOC:als, GOC:TermGenie, PMID:25651887] synonym: "activation of bleb assembly" NARROW [GOC:TermGenie] synonym: "activation of cell blebbing" NARROW [GOC:TermGenie] synonym: "positive regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "up-regulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cell blebbing" EXACT [GOC:TermGenie] synonym: "upregulation of bleb assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cell blebbing" EXACT [GOC:TermGenie] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:1904170 ! regulation of bleb assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0032060 ! bleb assembly relationship: positively_regulates GO:0032060 ! bleb assembly created_by: als creation_date: 2015-04-23T09:32:31Z [Term] id: GO:1904177 name: regulation of adipose tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "regulation of adipogenesis" RELATED [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060612 ! adipose tissue development relationship: regulates GO:0060612 ! adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:01Z [Term] id: GO:1904178 name: negative regulation of adipose tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "down regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "down regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of adipogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of adipose tissue development" NARROW [GOC:TermGenie] synonym: "negative regulation of adipogenesis" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060612 ! adipose tissue development relationship: negatively_regulates GO:0060612 ! adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:07Z [Term] id: GO:1904179 name: positive regulation of adipose tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of adipose tissue development." [GO_REF:0000058, GOC:TermGenie, PMID:23081848] synonym: "activation of adipogenesis" RELATED [GOC:TermGenie] synonym: "activation of adipose tissue development" NARROW [GOC:TermGenie] synonym: "positive regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of adipose tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of adipogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of adipose tissue development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904177 ! regulation of adipose tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060612 ! adipose tissue development relationship: positively_regulates GO:0060612 ! adipose tissue development created_by: sl creation_date: 2015-04-29T20:01:13Z [Term] id: GO:1904192 name: regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902488 ! cholangiocyte apoptotic process relationship: regulates GO:1902488 ! cholangiocyte apoptotic process created_by: sl creation_date: 2015-05-06T15:25:48Z [Term] id: GO:1904193 name: negative regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "down regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process relationship: negatively_regulates GO:1902488 ! cholangiocyte apoptotic process created_by: sl creation_date: 2015-05-06T15:25:55Z [Term] id: GO:1904194 name: positive regulation of cholangiocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:24498161] synonym: "activation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of cholangiocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "activation of epithelial cell of bile duct apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of cholangiocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of cholangiocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial cell of bile duct apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of epithelial cell of bile duct apoptotic process" EXACT [GOC:TermGenie] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:1904192 ! regulation of cholangiocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902488 ! cholangiocyte apoptotic process relationship: positively_regulates GO:1902488 ! cholangiocyte apoptotic process created_by: sl creation_date: 2015-05-06T15:26:00Z [Term] id: GO:1904204 name: regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] is_a: GO:0014733 ! regulation of skeletal muscle adaptation is_a: GO:0014743 ! regulation of muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014734 ! skeletal muscle hypertrophy relationship: regulates GO:0014734 ! skeletal muscle hypertrophy created_by: sl creation_date: 2015-05-08T17:38:13Z [Term] id: GO:1904205 name: negative regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "down regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "inhibition of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy relationship: negatively_regulates GO:0014734 ! skeletal muscle hypertrophy created_by: sl creation_date: 2015-05-08T17:38:19Z [Term] id: GO:1904206 name: positive regulation of skeletal muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy." [GO_REF:0000058, GOC:TermGenie, PMID:23470307] synonym: "activation of skeletal muscle hypertrophy" NARROW [GOC:TermGenie] synonym: "up regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of skeletal muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1904204 ! regulation of skeletal muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014734 ! skeletal muscle hypertrophy relationship: positively_regulates GO:0014734 ! skeletal muscle hypertrophy created_by: sl creation_date: 2015-05-08T17:38:25Z [Term] id: GO:1904251 name: regulation of bile acid metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "regulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0019218 ! regulation of steroid metabolic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0062012 ! regulation of small molecule metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008206 ! bile acid metabolic process relationship: regulates GO:0008206 ! bile acid metabolic process created_by: bf creation_date: 2015-05-20T11:04:28Z [Term] id: GO:1904252 name: negative regulation of bile acid metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "down regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "down regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "down-regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "downregulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "downregulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "inhibition of bile acid metabolic process" NARROW [GOC:TermGenie] synonym: "inhibition of bile acid metabolism" NARROW [GOC:TermGenie] synonym: "negative regulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0045939 ! negative regulation of steroid metabolic process is_a: GO:0062014 ! negative regulation of small molecule metabolic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008206 ! bile acid metabolic process relationship: negatively_regulates GO:0008206 ! bile acid metabolic process created_by: bf creation_date: 2015-05-20T11:04:35Z [Term] id: GO:1904253 name: positive regulation of bile acid metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of bile acid metabolic process." [GO_REF:0000058, GOC:bf, GOC:TermGenie] synonym: "activation of bile acid metabolic process" NARROW [GOC:TermGenie] synonym: "activation of bile acid metabolism" NARROW [GOC:TermGenie] synonym: "positive regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "up regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "up regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "up-regulation of bile acid metabolism" EXACT [GOC:TermGenie] synonym: "upregulation of bile acid metabolic process" EXACT [GOC:TermGenie] synonym: "upregulation of bile acid metabolism" EXACT [GOC:TermGenie] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0045940 ! positive regulation of steroid metabolic process is_a: GO:0062013 ! positive regulation of small molecule metabolic process is_a: GO:1904251 ! regulation of bile acid metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008206 ! bile acid metabolic process relationship: positively_regulates GO:0008206 ! bile acid metabolic process created_by: bf creation_date: 2015-05-20T11:04:40Z [Term] id: GO:1904269 name: cell leading edge cell cortex namespace: cellular_component def: "The cell cortex of the leading edge of a cell." [GO_REF:0000064, GOC:kmv, GOC:TermGenie, PMID:25843030] synonym: "cell cortex of cell leading edge" EXACT [GOC:TermGenie] synonym: "cell cortex of front of cell" EXACT [GOC:TermGenie] synonym: "cell cortex of leading edge of cell" EXACT [GOC:TermGenie] synonym: "cell periphery of cell leading edge" RELATED [GOC:TermGenie] synonym: "cell periphery of front of cell" RELATED [GOC:TermGenie] synonym: "cell periphery of leading edge of cell" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of cell leading edge" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of front of cell" RELATED [GOC:TermGenie] synonym: "peripheral cytoplasm of leading edge of cell" RELATED [GOC:TermGenie] is_a: GO:0099738 ! cell cortex region intersection_of: GO:0099738 ! cell cortex region intersection_of: part_of GO:0031252 ! cell leading edge relationship: part_of GO:0031252 ! cell leading edge created_by: kmv creation_date: 2015-05-28T19:16:03Z [Term] id: GO:1904304 name: regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] is_a: GO:0006940 ! regulation of smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction relationship: regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction created_by: sl creation_date: 2015-06-09T23:18:42Z [Term] id: GO:1904305 name: negative regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "down regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction relationship: negatively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction created_by: sl creation_date: 2015-06-09T23:18:48Z [Term] id: GO:1904306 name: positive regulation of gastro-intestinal system smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:10821044] synonym: "activation of gastro-intestinal system smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of gastro-intestinal system smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction relationship: positively_regulates GO:0014831 ! gastro-intestinal system smooth muscle contraction created_by: sl creation_date: 2015-06-09T23:18:54Z [Term] id: GO:1904318 name: regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0006940 ! regulation of smooth muscle contraction is_a: GO:0044062 ! regulation of excretion is_a: GO:0098801 ! regulation of renal system process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060083 ! smooth muscle contraction involved in micturition relationship: regulates GO:0060083 ! smooth muscle contraction involved in micturition created_by: sl creation_date: 2015-06-10T18:46:11Z [Term] id: GO:1904319 name: negative regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "down regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "down regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "down regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "down-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "down-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "downregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "downregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "inhibition of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] synonym: "inhibition of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "inhibition of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "negative regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "negative regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0045986 ! negative regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition relationship: negatively_regulates GO:0060083 ! smooth muscle contraction involved in micturition created_by: sl creation_date: 2015-06-10T18:46:17Z [Term] id: GO:1904320 name: positive regulation of smooth muscle contraction involved in micturition namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition." [GO_REF:0000058, GOC:TermGenie, PMID:18562635] synonym: "activation of smooth muscle contraction involved in micturition" NARROW [GOC:TermGenie] synonym: "activation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "activation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "positive regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "positive regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "up regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "up regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "up regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "up-regulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "up-regulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] synonym: "upregulation of smooth muscle contraction involved in micturition" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle contraction involved in urination" RELATED [GOC:TermGenie] synonym: "upregulation of urinary bladder smooth muscle contraction involved in micturition" RELATED [GOC:TermGenie] is_a: GO:0045987 ! positive regulation of smooth muscle contraction is_a: GO:1904318 ! regulation of smooth muscle contraction involved in micturition intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition relationship: positively_regulates GO:0060083 ! smooth muscle contraction involved in micturition created_by: sl creation_date: 2015-06-10T18:46:23Z [Term] id: GO:1904341 name: regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990765 ! colon smooth muscle contraction relationship: regulates GO:1990765 ! colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:16:58Z [Term] id: GO:1904342 name: negative regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "down regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of colon smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990765 ! colon smooth muscle contraction relationship: negatively_regulates GO:1990765 ! colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:17:05Z [Term] id: GO:1904343 name: positive regulation of colon smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:24170253] synonym: "activation of colon smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of colon smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904341 ! regulation of colon smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990765 ! colon smooth muscle contraction relationship: positively_regulates GO:1990765 ! colon smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:17:11Z [Term] id: GO:1904344 name: regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903522 ! regulation of blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990768 ! gastric mucosal blood circulation relationship: regulates GO:1990768 ! gastric mucosal blood circulation created_by: sl creation_date: 2015-06-11T21:20:31Z [Term] id: GO:1904345 name: negative regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "down regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "down-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "downregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "inhibition of gastric mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "inhibition of stomach mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "negative regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903523 ! negative regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990768 ! gastric mucosal blood circulation relationship: negatively_regulates GO:1990768 ! gastric mucosal blood circulation created_by: sl creation_date: 2015-06-11T21:20:44Z [Term] id: GO:1904346 name: positive regulation of gastric mucosal blood circulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation." [GO_REF:0000058, GOC:TermGenie, PMID:10807413] synonym: "activation of gastric mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "activation of stomach mucosal blood circulation" NARROW [GOC:TermGenie] synonym: "positive regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "up-regulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of gastric mucosal blood circulation" EXACT [GOC:TermGenie] synonym: "upregulation of stomach mucosal blood circulation" EXACT [GOC:TermGenie] is_a: GO:1903524 ! positive regulation of blood circulation is_a: GO:1904344 ! regulation of gastric mucosal blood circulation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990768 ! gastric mucosal blood circulation relationship: positively_regulates GO:1990768 ! gastric mucosal blood circulation created_by: sl creation_date: 2015-06-11T21:20:50Z [Term] id: GO:1904347 name: regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] is_a: GO:1904304 ! regulation of gastro-intestinal system smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990770 ! small intestine smooth muscle contraction relationship: regulates GO:1990770 ! small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:34Z [Term] id: GO:1904348 name: negative regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "down regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "down-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "downregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "inhibition of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] is_a: GO:1904305 ! negative regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction relationship: negatively_regulates GO:1990770 ! small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:40Z [Term] id: GO:1904349 name: positive regulation of small intestine smooth muscle contraction namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction." [GO_REF:0000058, GOC:TermGenie, PMID:11991626] synonym: "activation of small intestine smooth muscle contraction" NARROW [GOC:TermGenie] synonym: "up regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "up-regulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] synonym: "upregulation of small intestine smooth muscle contraction" EXACT [GOC:TermGenie] is_a: GO:1904306 ! positive regulation of gastro-intestinal system smooth muscle contraction is_a: GO:1904347 ! regulation of small intestine smooth muscle contraction intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990770 ! small intestine smooth muscle contraction relationship: positively_regulates GO:1990770 ! small intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T21:37:46Z [Term] id: GO:1904350 name: regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0042176 ! regulation of protein catabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007039 ! protein catabolic process in the vacuole relationship: regulates GO:0007039 ! protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:36Z [Term] id: GO:1904351 name: negative regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "down regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "down regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "down regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "down-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "down-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "down-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "downregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "downregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "downregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "inhibition of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] synonym: "inhibition of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "inhibition of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "negative regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0042177 ! negative regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole relationship: negatively_regulates GO:0007039 ! protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:42Z [Term] id: GO:1904352 name: positive regulation of protein catabolic process in the vacuole namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:25635054] synonym: "activation of protein catabolic process in the vacuole" NARROW [GOC:TermGenie] synonym: "activation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "activation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "positive regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "up regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "up regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "up regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "up-regulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "up-regulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "up-regulation of vacuolar protein degradation" RELATED [GOC:TermGenie] synonym: "upregulation of protein catabolic process in the vacuole" EXACT [GOC:TermGenie] synonym: "upregulation of vacuolar protein breakdown" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein catabolic process" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein catabolism" RELATED [GOC:TermGenie] synonym: "upregulation of vacuolar protein degradation" RELATED [GOC:TermGenie] is_a: GO:0045732 ! positive regulation of protein catabolic process is_a: GO:1904350 ! regulation of protein catabolic process in the vacuole intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007039 ! protein catabolic process in the vacuole relationship: positively_regulates GO:0007039 ! protein catabolic process in the vacuole created_by: rl creation_date: 2015-06-12T09:10:49Z [Term] id: GO:1904375 name: regulation of protein localization to cell periphery namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990778 ! protein localization to cell periphery relationship: regulates GO:1990778 ! protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:25Z [Term] id: GO:1904376 name: negative regulation of protein localization to cell periphery namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "down regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "inhibition of protein localization to cell periphery" NARROW [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990778 ! protein localization to cell periphery relationship: negatively_regulates GO:1990778 ! protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:32Z [Term] id: GO:1904377 name: positive regulation of protein localization to cell periphery namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery." [GO_REF:0000058, GOC:TermGenie, PMID:18216290] synonym: "activation of protein localization to cell periphery" NARROW [GOC:TermGenie] synonym: "up regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell periphery" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell periphery" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990778 ! protein localization to cell periphery relationship: positively_regulates GO:1990778 ! protein localization to cell periphery created_by: sl creation_date: 2015-06-22T22:09:37Z [Term] id: GO:1904396 name: regulation of neuromuscular junction development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "regulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007528 ! neuromuscular junction development relationship: regulates GO:0007528 ! neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:42Z [Term] id: GO:1904397 name: negative regulation of neuromuscular junction development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "down regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "down regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "down regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "down-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "down-regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "downregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "downregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "downregulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "inhibition of neuromuscular junction development" NARROW [GOC:TermGenie] synonym: "inhibition of neuromuscular junction organization" NARROW [GOC:TermGenie] synonym: "inhibition of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "inhibition of NMJ stability" RELATED [GOC:TermGenie] synonym: "negative regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "negative regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "negative regulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:1904396 ! regulation of neuromuscular junction development is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007528 ! neuromuscular junction development relationship: negatively_regulates GO:0007528 ! neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:48Z [Term] id: GO:1904398 name: positive regulation of neuromuscular junction development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development." [GO_REF:0000058, GOC:TermGenie, PMID:7722643] synonym: "activation of neuromuscular junction development" NARROW [GOC:TermGenie] synonym: "activation of neuromuscular junction organization" NARROW [GOC:TermGenie] synonym: "activation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "activation of NMJ stability" RELATED [GOC:TermGenie] synonym: "positive regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "positive regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "positive regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "up regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "up regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "up-regulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "up-regulation of NMJ stability" RELATED [GOC:TermGenie] synonym: "upregulation of neuromuscular junction development" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction organization" EXACT [GOC:TermGenie] synonym: "upregulation of neuromuscular junction stability" RELATED [GOC:TermGenie] synonym: "upregulation of NMJ stability" RELATED [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1904396 ! regulation of neuromuscular junction development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007528 ! neuromuscular junction development relationship: positively_regulates GO:0007528 ! neuromuscular junction development created_by: sl creation_date: 2015-06-23T19:23:54Z [Term] id: GO:1904409 name: regulation of secretory granule organization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0033043 ! regulation of organelle organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033363 ! secretory granule organization relationship: regulates GO:0033363 ! secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:42Z [Term] id: GO:1904410 name: negative regulation of secretory granule organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "down regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "down regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "down-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "downregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of secretory granule organisation" NARROW [GOC:TermGenie] synonym: "inhibition of secretory granule organization" NARROW [GOC:TermGenie] synonym: "inhibition of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033363 ! secretory granule organization relationship: negatively_regulates GO:0033363 ! secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:49Z [Term] id: GO:1904411 name: positive regulation of secretory granule organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of secretory granule organization." [GO_REF:0000058, GOC:TermGenie, PMID:15039777] synonym: "activation of secretory granule organisation" NARROW [GOC:TermGenie] synonym: "activation of secretory granule organization" NARROW [GOC:TermGenie] synonym: "activation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "positive regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "up regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "up-regulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "up-regulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] synonym: "upregulation of secretory granule organisation" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organization" EXACT [GOC:TermGenie] synonym: "upregulation of secretory granule organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:1904409 ! regulation of secretory granule organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033363 ! secretory granule organization relationship: positively_regulates GO:0033363 ! secretory granule organization created_by: sl creation_date: 2015-06-25T19:40:55Z [Term] id: GO:1904412 name: regulation of cardiac ventricle development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003231 ! cardiac ventricle development relationship: regulates GO:0003231 ! cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:15Z [Term] id: GO:1904413 name: negative regulation of cardiac ventricle development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "down regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac ventricle development" NARROW [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003231 ! cardiac ventricle development relationship: negatively_regulates GO:0003231 ! cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:21Z [Term] id: GO:1904414 name: positive regulation of cardiac ventricle development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development." [GO_REF:0000058, GOC:TermGenie, PMID:19590510] synonym: "activation of cardiac ventricle development" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle development" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1904412 ! regulation of cardiac ventricle development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003231 ! cardiac ventricle development relationship: positively_regulates GO:0003231 ! cardiac ventricle development created_by: sl creation_date: 2015-06-25T19:52:27Z [Term] id: GO:1904456 name: negative regulation of neuronal action potential namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "down regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "down regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "down-regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "down-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "downregulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "downregulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "inhibition of generation of action potential" RELATED [GOC:TermGenie] synonym: "inhibition of neuronal action potential" NARROW [GOC:TermGenie] synonym: "negative regulation of generation of action potential" RELATED [GOC:TermGenie] is_a: GO:0045759 ! negative regulation of action potential is_a: GO:0051970 ! negative regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0019228 ! neuronal action potential relationship: negatively_regulates GO:0019228 ! neuronal action potential created_by: sl creation_date: 2015-07-09T18:02:40Z [Term] id: GO:1904457 name: positive regulation of neuronal action potential namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuronal action potential." [GO_REF:0000058, GOC:TermGenie, PMID:25126967] synonym: "activation of generation of action potential" RELATED [GOC:TermGenie] synonym: "activation of neuronal action potential" NARROW [GOC:TermGenie] synonym: "positive regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "up-regulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "up-regulation of neuronal action potential" EXACT [GOC:TermGenie] synonym: "upregulation of generation of action potential" RELATED [GOC:TermGenie] synonym: "upregulation of neuronal action potential" EXACT [GOC:TermGenie] is_a: GO:0045760 ! positive regulation of action potential is_a: GO:0051971 ! positive regulation of transmission of nerve impulse is_a: GO:0098908 ! regulation of neuronal action potential intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0019228 ! neuronal action potential relationship: positively_regulates GO:0019228 ! neuronal action potential created_by: sl creation_date: 2015-07-09T18:02:46Z [Term] id: GO:1904484 name: cloacal gland development namespace: biological_process def: "The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure." [GO_REF:0000094, GOC:mr, GOC:TermGenie, PMID:18805421] is_a: GO:0048732 ! gland development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0012478 ! cloacal gland relationship: results_in_development_of UBERON:0012478 ! cloacal gland created_by: mr creation_date: 2015-07-15T22:14:39Z [Term] id: GO:1904491 name: protein localization to ciliary transition zone namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone." [GO_REF:0000087, GOC:kmv, GOC:TermGenie, PMID:21422230] synonym: "protein localisation in ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localisation to ciliary transition zone" EXACT [GOC:TermGenie] synonym: "protein localization in ciliary transition zone" EXACT [GOC:TermGenie] is_a: GO:0061512 ! protein localization to cilium intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0035869 ! ciliary transition zone relationship: has_target_end_location GO:0035869 ! ciliary transition zone created_by: kmv creation_date: 2015-07-17T20:43:21Z [Term] id: GO:1904587 name: response to glycoprotein namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:14597422] synonym: "response to glycoproteins" EXACT [] is_a: GO:0010243 ! response to organonitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:17089 ! glycoprotein relationship: has_input CHEBI:17089 ! glycoprotein created_by: sl creation_date: 2015-08-20T16:46:24Z [Term] id: GO:1904606 name: fat cell apoptotic process namespace: biological_process def: "Any apoptotic process in a fat cell." [GO_REF:0000085, GOC:TermGenie, PMID:17024416] synonym: "adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000136 ! fat cell relationship: occurs_in CL:0000136 ! fat cell created_by: sl creation_date: 2015-08-27T18:13:06Z [Term] id: GO:1904649 name: regulation of fat cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904606 ! fat cell apoptotic process relationship: regulates GO:1904606 ! fat cell apoptotic process created_by: sl creation_date: 2015-08-31T20:59:28Z [Term] id: GO:1904650 name: negative regulation of fat cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "down regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of adipocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of adipose cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of fat cell apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of fat cell apoptosis" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904606 ! fat cell apoptotic process relationship: negatively_regulates GO:1904606 ! fat cell apoptotic process created_by: sl creation_date: 2015-08-31T20:59:34Z [Term] id: GO:1904651 name: positive regulation of fat cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process." [GO_REF:0000058, GOC:TermGenie, PMID:17024416] synonym: "activation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "activation of adipocyte apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of adipose cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of fat cell apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of fat cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipocyte apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of adipocyte apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of adipose cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of adipose cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of fat cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of fat cell apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:1904649 ! regulation of fat cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904606 ! fat cell apoptotic process relationship: positively_regulates GO:1904606 ! fat cell apoptotic process created_by: sl creation_date: 2015-08-31T20:59:40Z [Term] id: GO:1904659 name: glucose transmembrane transport namespace: biological_process alt_id: GO:0015758 def: "The process in which glucose is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:9090050] synonym: "glucose transport" RELATED [] is_a: GO:0008645 ! hexose transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:17234 ! glucose intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:17234 ! glucose created_by: vw creation_date: 2015-09-04T17:20:16Z [Term] id: GO:1904671 name: negative regulation of cell differentiation involved in stem cell population maintenance namespace: biological_process def: "Any negative regulation of cell differentiation that is involved in stem cell population maintenance." [GO_REF:0000060, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "down-regulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "downregulation of cell differentiation involved in stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] synonym: "inhibition of cell differentiation involved in stem cell population maintenance" NARROW [GOC:TermGenie] synonym: "negative regulation of cell differentiation involved in maintenance of pluripotency" RELATED [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation intersection_of: GO:0045596 ! negative regulation of cell differentiation intersection_of: part_of GO:0019827 ! stem cell population maintenance relationship: part_of GO:0019827 ! stem cell population maintenance created_by: tb creation_date: 2015-09-12T00:46:08Z [Term] id: GO:1904672 name: regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] is_a: GO:2000036 ! regulation of stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035019 ! somatic stem cell population maintenance relationship: regulates GO:0035019 ! somatic stem cell population maintenance created_by: rph creation_date: 2015-09-14T08:40:19Z [Term] id: GO:1904673 name: negative regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "inhibition of somatic stem cell population maintenance" NARROW [GOC:TermGenie] is_a: GO:1902455 ! negative regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035019 ! somatic stem cell population maintenance relationship: negatively_regulates GO:0035019 ! somatic stem cell population maintenance created_by: rph creation_date: 2015-09-14T08:40:25Z [Term] id: GO:1904674 name: positive regulation of somatic stem cell population maintenance namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "activation of somatic stem cell population maintenance" NARROW [GOC:TermGenie] synonym: "up regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell population maintenance" EXACT [GOC:TermGenie] is_a: GO:1902459 ! positive regulation of stem cell population maintenance is_a: GO:1904672 ! regulation of somatic stem cell population maintenance intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035019 ! somatic stem cell population maintenance relationship: positively_regulates GO:0035019 ! somatic stem cell population maintenance created_by: rph creation_date: 2015-09-14T08:40:32Z [Term] id: GO:1904675 name: regulation of somatic stem cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:2000035 ! regulation of stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048103 ! somatic stem cell division relationship: regulates GO:0048103 ! somatic stem cell division created_by: rph creation_date: 2015-09-14T08:47:22Z [Term] id: GO:1904676 name: negative regulation of somatic stem cell division namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "down regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "down-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "downregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "inhibition of somatic stem cell division" NARROW [GOC:TermGenie] synonym: "inhibition of somatic stem cell renewal" NARROW [GOC:TermGenie] synonym: "negative regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051782 ! negative regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048103 ! somatic stem cell division relationship: negatively_regulates GO:0048103 ! somatic stem cell division created_by: rph creation_date: 2015-09-14T08:47:28Z [Term] id: GO:1904677 name: positive regulation of somatic stem cell division namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of somatic stem cell division." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19409607] synonym: "activation of somatic stem cell division" NARROW [GOC:TermGenie] synonym: "activation of somatic stem cell renewal" NARROW [GOC:TermGenie] synonym: "positive regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "up-regulation of somatic stem cell renewal" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell division" EXACT [GOC:TermGenie] synonym: "upregulation of somatic stem cell renewal" EXACT [GOC:TermGenie] is_a: GO:0051781 ! positive regulation of cell division is_a: GO:1904675 ! regulation of somatic stem cell division intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048103 ! somatic stem cell division relationship: positively_regulates GO:0048103 ! somatic stem cell division created_by: rph creation_date: 2015-09-14T08:47:34Z [Term] id: GO:1904680 name: peptide transmembrane transporter activity namespace: molecular_function alt_id: GO:0015197 alt_id: GO:0015637 def: "Enables the transfer of a peptide from one side of a membrane to the other." [GO_REF:0000070, GOC:TermGenie, GOC:vw] synonym: "peptide transporter activity" RELATED [] synonym: "peptide uptake permease activity" RELATED [] xref: Reactome:R-HSA-1500817 "Glutathione is taken up by the bacterium" is_a: GO:0042887 ! amide transmembrane transporter activity intersection_of: GO:0005215 ! transporter activity intersection_of: has_primary_input CHEBI:16670 ! peptide intersection_of: results_in_transport_across GO:0016020 ! membrane relationship: has_primary_input CHEBI:16670 ! peptide created_by: tb creation_date: 2015-09-22T18:50:41Z [Term] id: GO:1904691 name: negative regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "down regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of pancreatic B cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation relationship: negatively_regulates GO:0044342 ! type B pancreatic cell proliferation created_by: sl creation_date: 2015-09-25T15:23:38Z [Term] id: GO:1904692 name: positive regulation of type B pancreatic cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:24055447] synonym: "activation of pancreatic B cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of pancreatic beta cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of type B pancreatic cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic B cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of pancreatic beta cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of type B pancreatic cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:0061469 ! regulation of type B pancreatic cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044342 ! type B pancreatic cell proliferation relationship: positively_regulates GO:0044342 ! type B pancreatic cell proliferation created_by: sl creation_date: 2015-09-25T15:23:44Z [Term] id: GO:1904693 name: midbrain morphogenesis namespace: biological_process def: "The developmental process by which a midbrain is generated and organized." [GO_REF:0000083, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:21347250] synonym: "MB morphogenesis" BROAD [GOC:TermGenie] synonym: "mesencephalon morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0001891 ! midbrain relationship: part_of GO:0030901 ! midbrain development relationship: part_of GO:0048854 ! brain morphogenesis relationship: results_in_morphogenesis_of UBERON:0001891 ! midbrain created_by: bf creation_date: 2015-09-29T09:15:28Z [Term] id: GO:1904697 name: regulation of acinar cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990863 ! acinar cell proliferation relationship: regulates GO:1990863 ! acinar cell proliferation created_by: sl creation_date: 2015-09-30T15:19:50Z [Term] id: GO:1904698 name: negative regulation of acinar cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "down regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of acinar cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of acinic cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of acinous cell proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "negative regulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990863 ! acinar cell proliferation relationship: negatively_regulates GO:1990863 ! acinar cell proliferation created_by: sl creation_date: 2015-09-30T15:19:57Z [Term] id: GO:1904699 name: positive regulation of acinar cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:9788538] synonym: "activation of acinar cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of acinic cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of acinous cell proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "positive regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of acinous cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinar cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinic cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of acinous cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0050679 ! positive regulation of epithelial cell proliferation is_a: GO:1904697 ! regulation of acinar cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990863 ! acinar cell proliferation relationship: positively_regulates GO:1990863 ! acinar cell proliferation created_by: sl creation_date: 2015-09-30T15:20:03Z [Term] id: GO:1904705 name: regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048660 ! regulation of smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1990874 ! vascular associated smooth muscle cell proliferation relationship: regulates GO:1990874 ! vascular associated smooth muscle cell proliferation created_by: sl creation_date: 2015-10-01T16:05:20Z [Term] id: GO:1904706 name: negative regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "down regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC proliferation" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "negative regulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048662 ! negative regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation relationship: negatively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation created_by: sl creation_date: 2015-10-01T16:05:26Z [Term] id: GO:1904707 name: positive regulation of vascular associated smooth muscle cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:23246467] synonym: "activation of vascular smooth muscle cell proliferation" NARROW [GOC:TermGenie] synonym: "activation of VSMC proliferation" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell proliferation" EXACT [] synonym: "positive regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC proliferation" EXACT [GOC:TermGenie] is_a: GO:0048661 ! positive regulation of smooth muscle cell proliferation is_a: GO:1904705 ! regulation of vascular associated smooth muscle cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation relationship: positively_regulates GO:1990874 ! vascular associated smooth muscle cell proliferation created_by: sl creation_date: 2015-10-01T16:05:32Z [Term] id: GO:1904738 name: vascular associated smooth muscle cell migration namespace: biological_process def: "The orderly movement of a vascular associated smooth muscle cell from one site to another." [GO_REF:0000091, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "vascular smooth muscle cell migration" EXACT [] is_a: GO:0014909 ! smooth muscle cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000359 ! vascular associated smooth muscle cell relationship: results_in_movement_of CL:0000359 ! vascular associated smooth muscle cell created_by: rph creation_date: 2015-10-15T09:56:00Z [Term] id: GO:1904746 name: negative regulation of apoptotic process involved in development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: U4PR86 in PMID:22801495 inferred from mutant phenotype synonym: "down regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "down-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "downregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "downregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "inhibition of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "inhibition of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "negative regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902742 ! apoptotic process involved in development relationship: negatively_regulates GO:1902742 ! apoptotic process involved in development created_by: es creation_date: 2015-10-19T14:12:27Z [Term] id: GO:1904747 name: positive regulation of apoptotic process involved in development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: U4PR86 in PMID:22801495 inferred from mutant phenotype synonym: "activation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic process involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of apoptotic programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of programmed cell death by apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "activation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "activation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "activation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "positive regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "up-regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "upregulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "upregulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1904748 ! regulation of apoptotic process involved in development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902742 ! apoptotic process involved in development relationship: positively_regulates GO:1902742 ! apoptotic process involved in development created_by: es creation_date: 2015-10-19T14:12:34Z [Term] id: GO:1904748 name: regulation of apoptotic process involved in development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." [GO_REF:0000058, GOC:TermGenie, PMID:22801495] comment: Q10943 in PMID:22801495, inferred from mutant phenotype synonym: "regulation of activation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of activation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis activator activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis activator activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of apoptosis involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis signaling involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptosis signaling involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic process involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic program involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic program involved in development of an anatomical structure" NARROW [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of apoptotic programmed cell death involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of commitment to apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of commitment to apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis by p53 involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis by p53 involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of induction of apoptosis involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in anatomical structure development" EXACT [GOC:TermGenie] synonym: "regulation of programmed cell death by apoptosis involved in development of an anatomical structure" EXACT [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity involved in anatomical structure development" RELATED [GOC:TermGenie] synonym: "regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" RELATED [GOC:TermGenie] synonym: "regulation of type I programmed cell death involved in anatomical structure development" NARROW [GOC:TermGenie] synonym: "regulation of type I programmed cell death involved in development of an anatomical structure" NARROW [GOC:TermGenie] is_a: GO:0042981 ! regulation of apoptotic process is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902742 ! apoptotic process involved in development relationship: regulates GO:1902742 ! apoptotic process involved in development created_by: es creation_date: 2015-10-19T15:02:28Z [Term] id: GO:1904749 name: regulation of protein localization to nucleolus namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900180 ! regulation of protein localization to nucleus intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902570 ! protein localization to nucleolus relationship: regulates GO:1902570 ! protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:17Z [Term] id: GO:1904750 name: negative regulation of protein localization to nucleolus namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "down regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in nucleolus" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to nucleolus" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900181 ! negative regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902570 ! protein localization to nucleolus relationship: negatively_regulates GO:1902570 ! protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:24Z [Term] id: GO:1904751 name: positive regulation of protein localization to nucleolus namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:24415760] synonym: "activation of protein localisation in nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localization in nucleolus" NARROW [GOC:TermGenie] synonym: "activation of protein localization to nucleolus" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in nucleolus" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to nucleolus" EXACT [GOC:TermGenie] is_a: GO:1900182 ! positive regulation of protein localization to nucleus is_a: GO:1904749 ! regulation of protein localization to nucleolus intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902570 ! protein localization to nucleolus relationship: positively_regulates GO:1902570 ! protein localization to nucleolus created_by: nc creation_date: 2015-10-19T15:16:30Z [Term] id: GO:1904752 name: regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014910 ! regulation of smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1904738 ! vascular associated smooth muscle cell migration relationship: regulates GO:1904738 ! vascular associated smooth muscle cell migration created_by: rph creation_date: 2015-10-19T15:49:52Z [Term] id: GO:1904753 name: negative regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "down regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014912 ! negative regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration relationship: negatively_regulates GO:1904738 ! vascular associated smooth muscle cell migration created_by: rph creation_date: 2015-10-19T15:49:58Z [Term] id: GO:1904754 name: positive regulation of vascular associated smooth muscle cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:20693317] synonym: "activation of vascular associated smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell migration" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell migration" EXACT [GOC:TermGenie] is_a: GO:0014911 ! positive regulation of smooth muscle cell migration is_a: GO:1904752 ! regulation of vascular associated smooth muscle cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration relationship: positively_regulates GO:1904738 ! vascular associated smooth muscle cell migration created_by: rph creation_date: 2015-10-19T15:50:05Z [Term] id: GO:1904770 name: intramembranous bone morphogenesis namespace: biological_process def: "The developmental process by which an intramembranous bone is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:26399686] synonym: "intramembranous bones morphogenesis" RELATED [GOC:TermGenie] synonym: "membrane bone morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0060349 ! bone morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002514 ! intramembranous bone relationship: results_in_morphogenesis_of UBERON:0002514 ! intramembranous bone created_by: dos creation_date: 2015-10-28T11:46:04Z [Term] id: GO:1904776 name: regulation of protein localization to cell cortex namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904375 ! regulation of protein localization to cell periphery intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072697 ! protein localization to cell cortex relationship: regulates GO:0072697 ! protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:01Z [Term] id: GO:1904777 name: negative regulation of protein localization to cell cortex namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "down regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation to cell cortex" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to cell cortex" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904376 ! negative regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072697 ! protein localization to cell cortex relationship: negatively_regulates GO:0072697 ! protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:08Z [Term] id: GO:1904778 name: positive regulation of protein localization to cell cortex namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex." [GO_REF:0000058, GOC:TermGenie, PMID:17115027] comment: An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. synonym: "activation of protein localisation to cell cortex" NARROW [GOC:TermGenie] synonym: "activation of protein localization to cell cortex" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell cortex" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell cortex" EXACT [GOC:TermGenie] is_a: GO:1904377 ! positive regulation of protein localization to cell periphery is_a: GO:1904776 ! regulation of protein localization to cell cortex intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072697 ! protein localization to cell cortex relationship: positively_regulates GO:0072697 ! protein localization to cell cortex created_by: es creation_date: 2015-10-29T16:55:15Z [Term] id: GO:1904817 name: serous membrane development namespace: biological_process def: "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "serosa development" RELATED [GOC:TermGenie] synonym: "tunica serosa development" EXACT [GOC:TermGenie] synonym: "wall of serous sac development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0000042 ! serous membrane relationship: results_in_development_of UBERON:0000042 ! serous membrane created_by: dph creation_date: 2015-11-17T19:00:01Z [Term] id: GO:1904818 name: visceral peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001178 ! visceral peritoneum relationship: part_of GO:1904820 ! peritoneum development relationship: results_in_development_of UBERON:0001178 ! visceral peritoneum created_by: dph creation_date: 2015-11-17T19:00:17Z [Term] id: GO:1904819 name: parietal peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "peritoneal cavity lining development" EXACT [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001366 ! parietal peritoneum relationship: part_of GO:1904820 ! peritoneum development relationship: results_in_development_of UBERON:0001366 ! parietal peritoneum created_by: dph creation_date: 2015-11-17T19:00:24Z [Term] id: GO:1904820 name: peritoneum development namespace: biological_process def: "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure." [GO_REF:0000094, GOC:dph, GOC:TermGenie, PMID:15840053] synonym: "peritonaeum development" RELATED [GOC:TermGenie] is_a: GO:1904817 ! serous membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0002358 ! peritoneum relationship: results_in_development_of UBERON:0002358 ! peritoneum created_by: dph creation_date: 2015-11-18T17:23:51Z [Term] id: GO:1904829 name: regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035887 ! aortic smooth muscle cell differentiation relationship: regulates GO:0035887 ! aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:40Z [Term] id: GO:1904830 name: negative regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "down regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905064 ! negative regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation relationship: negatively_regulates GO:0035887 ! aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:47Z [Term] id: GO:1904831 name: positive regulation of aortic smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:22034194] synonym: "activation of aortic smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of aortic smooth muscle cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1904829 ! regulation of aortic smooth muscle cell differentiation is_a: GO:1905065 ! positive regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation relationship: positively_regulates GO:0035887 ! aortic smooth muscle cell differentiation created_by: rph creation_date: 2015-11-24T10:20:54Z [Term] id: GO:1904836 name: facioacoustic ganglion morphogenesis namespace: biological_process def: "The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized." [GO_REF:0000083, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] synonym: "acoustico-facial VII-VIII ganglion complex morphogenesis" EXACT [UBERON:0012175] synonym: "acousticofacial ganglion morphogenesis" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion complex morphogenesis" RELATED [GOC:TermGenie] synonym: "facio-acoustic ganglion complex VII-VIII morphogenesis" EXACT [GOC:TermGenie] synonym: "facio-acoustic ganglion morphogenesis" EXACT [GOC:TermGenie] synonym: "facio-acoustic VII-VIII ganglion complex morphogenesis" RELATED [GOC:TermGenie] is_a: GO:0061559 ! cranial ganglion morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0012175 ! acoustico-facial VII-VIII ganglion complex relationship: part_of GO:1903375 ! facioacoustic ganglion development relationship: results_in_morphogenesis_of UBERON:0012175 ! acoustico-facial VII-VIII ganglion complex created_by: bf creation_date: 2015-12-01T17:02:06Z [Term] id: GO:1904888 name: cranial skeletal system development namespace: biological_process def: "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000094, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:11262227] synonym: "cranial skeleton development" NARROW [GOC:TermGenie] synonym: "craniofacial development" NARROW [PMID:11262227] synonym: "cranium development" RELATED [GOC:TermGenie] synonym: "osteocranium development" NARROW [GOC:TermGenie] is_a: GO:0048856 ! anatomical structure development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0010323 ! cranial skeletal system relationship: results_in_development_of UBERON:0010323 ! cranial skeletal system created_by: bf creation_date: 2016-01-07T13:45:06Z [Term] id: GO:1904933 name: regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0033278 ! cell proliferation in midbrain relationship: regulates GO:0033278 ! cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:11Z [Term] id: GO:1904934 name: negative regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:18953410, PMID:24431302] synonym: "down regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "down regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "down-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "down-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "down-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "downregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "downregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "downregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "inhibition of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] synonym: "inhibition of cell proliferation in midbrain" NARROW [GOC:TermGenie] synonym: "inhibition of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "negative regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "negative regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000178 ! negative regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0033278 ! cell proliferation in midbrain relationship: negatively_regulates GO:0033278 ! cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:19Z [Term] id: GO:1904935 name: positive regulation of cell proliferation in midbrain namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24431302] synonym: "activation of cell proliferation in mesencephalon" NARROW [GOC:TermGenie] synonym: "activation of cell proliferation in midbrain" NARROW [GOC:TermGenie] synonym: "activation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "positive regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "positive regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "up regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "up regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "up-regulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "up-regulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "up-regulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] synonym: "upregulation of cell proliferation in mesencephalon" EXACT [GOC:TermGenie] synonym: "upregulation of cell proliferation in midbrain" EXACT [GOC:TermGenie] synonym: "upregulation of mesencepahalic cell proliferation" RELATED [GOC:TermGenie] is_a: GO:1904933 ! regulation of cell proliferation in midbrain is_a: GO:2000179 ! positive regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0033278 ! cell proliferation in midbrain relationship: positively_regulates GO:0033278 ! cell proliferation in midbrain created_by: bf creation_date: 2016-02-01T13:16:27Z [Term] id: GO:1904936 name: interneuron migration namespace: biological_process def: "The orderly movement of an interneuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] synonym: "inter neuron migration" EXACT [GOC:ah] synonym: "inter-neuron migration" EXACT [GOC:ah] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000099 ! interneuron relationship: results_in_movement_of CL:0000099 ! interneuron created_by: ah creation_date: 2016-02-01T14:04:32Z [Term] id: GO:1904937 name: sensory neuron migration namespace: biological_process def: "The orderly movement of a sensory neuron from one site to another." [GO_REF:0000091, GOC:ah, GOC:TermGenie, PMID:18622031] is_a: GO:0001764 ! neuron migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000101 ! sensory neuron relationship: results_in_movement_of CL:0000101 ! sensory neuron created_by: ah creation_date: 2016-02-01T14:15:50Z [Term] id: GO:1904942 name: regulation of cardiac ventricle formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] is_a: GO:1901210 ! regulation of cardiac chamber formation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003211 ! cardiac ventricle formation relationship: regulates GO:0003211 ! cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:16Z [Term] id: GO:1904943 name: negative regulation of cardiac ventricle formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "down regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac ventricle formation" NARROW [GOC:TermGenie] is_a: GO:1901211 ! negative regulation of cardiac chamber formation is_a: GO:1904413 ! negative regulation of cardiac ventricle development is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003211 ! cardiac ventricle formation relationship: negatively_regulates GO:0003211 ! cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:24Z [Term] id: GO:1904944 name: positive regulation of cardiac ventricle formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23575307] synonym: "activation of cardiac ventricle formation" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac ventricle formation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac ventricle formation" EXACT [GOC:TermGenie] is_a: GO:1901212 ! positive regulation of cardiac chamber formation is_a: GO:1904942 ! regulation of cardiac ventricle formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003211 ! cardiac ventricle formation relationship: positively_regulates GO:0003211 ! cardiac ventricle formation created_by: bc creation_date: 2016-02-02T16:37:31Z [Term] id: GO:1904950 name: negative regulation of establishment of protein localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "down regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "down-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "down-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "downregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "downregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "downregulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "inhibition of establishment of protein localisation" NARROW [GOC:TermGenie] synonym: "inhibition of establishment of protein localization" NARROW [GOC:TermGenie] synonym: "inhibition of protein positioning" NARROW [GOC:TermGenie] synonym: "inhibition of protein recruitment" NARROW [GOC:TermGenie] synonym: "negative regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "negative regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "negative regulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0070201 ! regulation of establishment of protein localization is_a: GO:1903828 ! negative regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045184 ! establishment of protein localization relationship: negatively_regulates GO:0045184 ! establishment of protein localization created_by: mec creation_date: 2016-02-05T09:59:24Z [Term] id: GO:1904951 name: positive regulation of establishment of protein localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." [GO_REF:0000058, GOC:TermGenie, PMID:22761445] synonym: "activation of establishment of protein localisation" NARROW [GOC:TermGenie] synonym: "activation of establishment of protein localization" NARROW [GOC:TermGenie] synonym: "activation of protein positioning" NARROW [GOC:TermGenie] synonym: "activation of protein recruitment" NARROW [GOC:TermGenie] synonym: "positive regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "positive regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "positive regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "up-regulation of protein positioning" EXACT [GOC:TermGenie] synonym: "up-regulation of protein recruitment" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localisation" EXACT [GOC:TermGenie] synonym: "upregulation of establishment of protein localization" EXACT [GOC:TermGenie] synonym: "upregulation of protein positioning" EXACT [GOC:TermGenie] synonym: "upregulation of protein recruitment" EXACT [GOC:TermGenie] is_a: GO:0070201 ! regulation of establishment of protein localization is_a: GO:1903829 ! positive regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0045184 ! establishment of protein localization relationship: positively_regulates GO:0045184 ! establishment of protein localization created_by: mec creation_date: 2016-02-05T09:59:32Z [Term] id: GO:1904987 name: regulation of endothelial cell activation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] is_a: GO:0050865 ! regulation of cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042118 ! endothelial cell activation relationship: regulates GO:0042118 ! endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:09Z [Term] id: GO:1904988 name: negative regulation of endothelial cell activation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "down regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial cell activation" NARROW [GOC:TermGenie] is_a: GO:0050866 ! negative regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042118 ! endothelial cell activation relationship: negatively_regulates GO:0042118 ! endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:18Z [Term] id: GO:1904989 name: positive regulation of endothelial cell activation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell activation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:24255059] synonym: "activation of endothelial cell activation" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial cell activation" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial cell activation" EXACT [GOC:TermGenie] is_a: GO:0050867 ! positive regulation of cell activation is_a: GO:1904987 ! regulation of endothelial cell activation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042118 ! endothelial cell activation relationship: positively_regulates GO:0042118 ! endothelial cell activation created_by: bc creation_date: 2016-02-29T16:16:25Z [Term] id: GO:1905039 name: carboxylic acid transmembrane transport namespace: biological_process def: "The process in which carboxylic acid is transported across a membrane." [GO_REF:0000069, GOC:TermGenie, PMID:10869563] is_a: GO:0046942 ! carboxylic acid transport is_a: GO:0055085 ! transmembrane transport intersection_of: GO:0006810 ! transport intersection_of: has_primary_input CHEBI:29067 ! carboxylic acid anion intersection_of: results_in_transport_across GO:0016020 ! membrane created_by: vw creation_date: 2016-03-09T15:33:53Z [Term] id: GO:1905040 name: otic placode development namespace: biological_process def: "The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure." [GO_REF:0000094, GOC:bf, GOC:mat, GOC:PARL, GOC:TermGenie, PMID:18356247] synonym: "auditory placode development" RELATED [GOC:TermGenie] synonym: "ear placode development" RELATED [GOC:TermGenie] synonym: "ear/otic placode development" RELATED [GOC:TermGenie] synonym: "octaval placode development" RELATED [GOC:TermGenie] synonym: "octaval VIII placode development" RELATED [GOC:TermGenie] synonym: "placoda otica development" EXACT [GOC:TermGenie] is_a: GO:0071696 ! ectodermal placode development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0003069 ! otic placode relationship: results_in_development_of UBERON:0003069 ! otic placode created_by: bf creation_date: 2016-03-10T09:30:20Z [Term] id: GO:1905063 name: regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: regulates GO:0035886 ! vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:14:53Z [Term] id: GO:1905064 name: negative regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "down regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: negatively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:15:03Z [Term] id: GO:1905065 name: positive regulation of vascular associated smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:19088079] synonym: "activation of vascular associated smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of VSMC differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC differentiation" EXACT [GOC:TermGenie] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:1905063 ! regulation of vascular associated smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation relationship: positively_regulates GO:0035886 ! vascular associated smooth muscle cell differentiation created_by: rph creation_date: 2016-03-21T11:15:13Z [Term] id: GO:1905069 name: allantois development namespace: biological_process def: "The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:17440924, PMID:21470579] synonym: "allantoic bud development" RELATED [GOC:TermGenie] is_a: GO:1903867 ! extraembryonic membrane development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0004340 ! allantois relationship: results_in_development_of UBERON:0004340 ! allantois created_by: cls creation_date: 2016-03-21T15:18:21Z [Term] id: GO:1905126 name: regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "regulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0033157 ! regulation of intracellular protein transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099640 ! axo-dendritic protein transport relationship: regulates GO:0099640 ! axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:31Z [Term] id: GO:1905127 name: negative regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "down regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "down regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "down-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "down-regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "downregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "downregulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "inhibition of axo-dendritic protein transport" NARROW [GOC:TermGenie] synonym: "inhibition of axonal protein transport" NARROW [GOC:TermGenie] synonym: "negative regulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0090317 ! negative regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0099640 ! axo-dendritic protein transport relationship: negatively_regulates GO:0099640 ! axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:40Z [Term] id: GO:1905128 name: positive regulation of axo-dendritic protein transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport." [GO_REF:0000058, GOC:TermGenie, PMID:20694152] synonym: "activation of axo-dendritic protein transport" NARROW [GOC:TermGenie] synonym: "activation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "positive regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "up regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "up regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "up-regulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "up-regulation of axonal protein transport" NARROW [GOC:TermGenie] synonym: "upregulation of axo-dendritic protein transport" EXACT [GOC:TermGenie] synonym: "upregulation of axonal protein transport" NARROW [GOC:TermGenie] is_a: GO:0090316 ! positive regulation of intracellular protein transport is_a: GO:1905126 ! regulation of axo-dendritic protein transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0099640 ! axo-dendritic protein transport relationship: positively_regulates GO:0099640 ! axo-dendritic protein transport created_by: sl creation_date: 2016-04-11T20:38:48Z [Term] id: GO:1905139 name: apical ectodermal ridge formation namespace: biological_process def: "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts." [GO_REF:0000081, GOC:TermGenie, PMID:18359901, PMID:9323126, PMID:9596583] synonym: "AER formation" RELATED [GOC:TermGenie] synonym: "apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: GO:0048646 ! anatomical structure formation involved in morphogenesis intersection_of: results_in_formation_of UBERON:0004356 ! apical ectodermal ridge relationship: part_of GO:0035107 ! appendage morphogenesis relationship: results_in_formation_of UBERON:0004356 ! apical ectodermal ridge created_by: dph creation_date: 2016-04-13T11:46:40Z [Term] id: GO:1905140 name: regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "regulation of AER formation" RELATED [GOC:TermGenie] synonym: "regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905139 ! apical ectodermal ridge formation relationship: regulates GO:1905139 ! apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:40Z [Term] id: GO:1905141 name: negative regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "down regulation of AER formation" RELATED [GOC:TermGenie] synonym: "down regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "down regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "down-regulation of AER formation" RELATED [GOC:TermGenie] synonym: "down-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "down-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "downregulation of AER formation" RELATED [GOC:TermGenie] synonym: "downregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "downregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "inhibition of AER formation" RELATED [GOC:TermGenie] synonym: "inhibition of apical ectodermal ridge formation" NARROW [GOC:TermGenie] synonym: "inhibition of apical epidermal ridge formation" NARROW [GOC:TermGenie] synonym: "inhibition of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "negative regulation of AER formation" RELATED [GOC:TermGenie] synonym: "negative regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "negative regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905139 ! apical ectodermal ridge formation relationship: negatively_regulates GO:1905139 ! apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:48Z [Term] id: GO:1905142 name: positive regulation of apical ectodermal ridge formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation." [GO_REF:0000058, GOC:TermGenie, PMID:18359901] synonym: "activation of AER formation" RELATED [GOC:TermGenie] synonym: "positive regulation of AER formation" RELATED [GOC:TermGenie] synonym: "positive regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "positive regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "up regulation of AER formation" RELATED [GOC:TermGenie] synonym: "up regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "up-regulation of AER formation" RELATED [GOC:TermGenie] synonym: "up-regulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "up-regulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] synonym: "upregulation of AER formation" RELATED [GOC:TermGenie] synonym: "upregulation of apical ectodermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of apical epidermal ridge formation" EXACT [GOC:TermGenie] synonym: "upregulation of crista ectodermalis apicalis formation" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905140 ! regulation of apical ectodermal ridge formation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905139 ! apical ectodermal ridge formation relationship: positively_regulates GO:1905139 ! apical ectodermal ridge formation created_by: dph creation_date: 2016-04-13T12:16:57Z [Term] id: GO:1905144 name: response to acetylcholine namespace: biological_process def: "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus." [GO_REF:0000071, GOC:TermGenie, PMID:21238497] is_a: GO:0010033 ! response to organic substance is_a: GO:1901698 ! response to nitrogen compound is_a: GO:1901700 ! response to oxygen-containing compound intersection_of: GO:0050896 ! response to stimulus intersection_of: has_input CHEBI:15355 ! acetylcholine relationship: has_input CHEBI:15355 ! acetylcholine created_by: dos creation_date: 2016-04-14T08:54:49Z [Term] id: GO:1905147 name: regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] is_a: GO:0014743 ! regulation of muscle hypertrophy is_a: GO:0043502 ! regulation of muscle adaptation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014895 ! smooth muscle hypertrophy relationship: regulates GO:0014895 ! smooth muscle hypertrophy created_by: bc creation_date: 2016-04-15T12:47:07Z [Term] id: GO:1905148 name: negative regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "down regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "inhibition of smooth muscle hypertrophy" NARROW [GOC:TermGenie] is_a: GO:0014741 ! negative regulation of muscle hypertrophy is_a: GO:0014745 ! negative regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014895 ! smooth muscle hypertrophy relationship: negatively_regulates GO:0014895 ! smooth muscle hypertrophy created_by: bc creation_date: 2016-04-15T12:47:16Z [Term] id: GO:1905149 name: positive regulation of smooth muscle hypertrophy namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:22161164] synonym: "activation of smooth muscle hypertrophy" NARROW [GOC:TermGenie] synonym: "up regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle hypertrophy" EXACT [GOC:TermGenie] is_a: GO:0014742 ! positive regulation of muscle hypertrophy is_a: GO:0014744 ! positive regulation of muscle adaptation is_a: GO:1905147 ! regulation of smooth muscle hypertrophy intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014895 ! smooth muscle hypertrophy relationship: positively_regulates GO:0014895 ! smooth muscle hypertrophy created_by: bc creation_date: 2016-04-15T12:47:24Z [Term] id: GO:1905207 name: regulation of cardiocyte differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035051 ! cardiocyte differentiation relationship: regulates GO:0035051 ! cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:01Z [Term] id: GO:1905208 name: negative regulation of cardiocyte differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "down regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of cardiocyte differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of heart cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "negative regulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035051 ! cardiocyte differentiation relationship: negatively_regulates GO:0035051 ! cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:09Z [Term] id: GO:1905209 name: positive regulation of cardiocyte differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation." [GO_REF:0000058, GOC:bc, GOC:BHF, GOC:BHF_miRNA, GOC:TermGenie, PMID:23069713] synonym: "activation of cardiac cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of cardiocyte differentiation" NARROW [GOC:TermGenie] synonym: "activation of heart cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "positive regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of heart cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of cardiocyte differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of heart cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035051 ! cardiocyte differentiation relationship: positively_regulates GO:0035051 ! cardiocyte differentiation created_by: bc creation_date: 2016-06-02T07:20:16Z [Term] id: GO:1905213 name: negative regulation of mitotic chromosome condensation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." [GO_REF:0000058, GOC:TermGenie, PMID:23219725] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:1902340 ! negative regulation of chromosome condensation is_a: GO:1903379 ! regulation of mitotic chromosome condensation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007076 ! mitotic chromosome condensation relationship: negatively_regulates GO:0007076 ! mitotic chromosome condensation created_by: vw creation_date: 2016-06-03T08:41:08Z [Term] id: GO:1905223 name: epicardium morphogenesis namespace: biological_process def: "The developmental process by which an epicardium is generated and organized." [GO_REF:0000083, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:18718461] synonym: "heart epicardium morphogenesis" EXACT [GOC:TermGenie] synonym: "pericardium visceral mesothelium morphogenesis" RELATED [GOC:TermGenie] synonym: "visceral serous pericardium of heart morphogenesis" EXACT [GOC:TermGenie] synonym: "visceral serous pericardium proper morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0002348 ! epicardium relationship: results_in_morphogenesis_of UBERON:0002348 ! epicardium created_by: rl creation_date: 2016-06-07T10:02:32Z [Term] id: GO:1905268 name: negative regulation of chromatin organization namespace: biological_process alt_id: GO:0045798 alt_id: GO:1903309 def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "down regulation of chromatin assembly or disassembly" RELATED [] synonym: "down regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin assembly or disassembly" RELATED [] synonym: "down-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "down-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin assembly or disassembly" RELATED [] synonym: "downregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "downregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "downregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "inhibition of chromatin assembly or disassembly" NARROW [] synonym: "inhibition of chromatin organisation" NARROW [GOC:TermGenie] synonym: "inhibition of chromatin organization" NARROW [GOC:TermGenie] synonym: "inhibition of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] synonym: "negative regulation of chromatin assembly or disassembly" RELATED [] synonym: "negative regulation of chromatin assembly/disassembly" EXACT [] synonym: "negative regulation of chromatin modification" RELATED [] synonym: "negative regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1902275 ! regulation of chromatin organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0006325 ! chromatin organization relationship: negatively_regulates GO:0006325 ! chromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI created_by: pr creation_date: 2016-06-15T20:14:47Z [Term] id: GO:1905269 name: positive regulation of chromatin organization namespace: biological_process alt_id: GO:0045799 alt_id: GO:1903310 def: "Any process that activates or increases the frequency, rate or extent of chromatin organization." [GO_REF:0000058, GOC:pr, GOC:TermGenie, GOC:vw, PMID:654321] synonym: "activation of chromatin assembly or disassembly" NARROW [] synonym: "activation of chromatin organisation" NARROW [GOC:TermGenie] synonym: "activation of chromatin organization" NARROW [GOC:TermGenie] synonym: "activation of establishment or maintenance of chromatin architecture" NARROW [GOC:TermGenie] synonym: "positive regulation of chromatin assembly or disassembly" RELATED [] synonym: "positive regulation of chromatin assembly/disassembly" RELATED [] synonym: "positive regulation of chromatin modification" RELATED [] synonym: "positive regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "positive regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "stimulation of chromatin assembly or disassembly" NARROW [] synonym: "up regulation of chromatin assembly or disassembly" RELATED [] synonym: "up regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin assembly or disassembly" RELATED [] synonym: "up-regulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "up-regulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin assembly or disassembly" EXACT [] synonym: "upregulation of chromatin organisation" EXACT [GOC:TermGenie] synonym: "upregulation of chromatin organization" EXACT [GOC:TermGenie] synonym: "upregulation of establishment or maintenance of chromatin architecture" EXACT [GOC:TermGenie] is_a: GO:1902275 ! regulation of chromatin organization is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0006325 ! chromatin organization relationship: positively_regulates GO:0006325 ! chromatin organization property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22766" xsd:anyURI created_by: pr creation_date: 2016-06-15T20:14:56Z [Term] id: GO:1905276 name: regulation of epithelial tube formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). is_a: GO:1905330 ! regulation of morphogenesis of an epithelium is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072175 ! epithelial tube formation relationship: regulates GO:0072175 ! epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:41Z [Term] id: GO:1905277 name: negative regulation of epithelial tube formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "down regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "downregulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "inhibition of epithelial tube formation" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072175 ! epithelial tube formation relationship: negatively_regulates GO:0072175 ! epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:49Z [Term] id: GO:1905278 name: positive regulation of epithelial tube formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial tube formation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "activation of epithelial tube formation" NARROW [GOC:TermGenie] synonym: "up regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelial tube formation" EXACT [GOC:TermGenie] synonym: "upregulation of epithelial tube formation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905276 ! regulation of epithelial tube formation is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072175 ! epithelial tube formation relationship: positively_regulates GO:0072175 ! epithelial tube formation created_by: bhm creation_date: 2016-06-20T09:35:57Z [Term] id: GO:1905288 name: vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any apoptotic process in a vascular associated smooth muscle cell." [GO_REF:0000085, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034390 ! smooth muscle cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0000359 ! vascular associated smooth muscle cell relationship: occurs_in CL:0000359 ! vascular associated smooth muscle cell created_by: rph creation_date: 2016-06-23T13:24:20Z [Term] id: GO:1905292 name: regulation of neural crest cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0014033 ! neural crest cell differentiation relationship: regulates GO:0014033 ! neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:01Z [Term] id: GO:1905293 name: negative regulation of neural crest cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "down regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of neural crest cell differentiation" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000737 ! negative regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0014033 ! neural crest cell differentiation relationship: negatively_regulates GO:0014033 ! neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:09Z [Term] id: GO:1905294 name: positive regulation of neural crest cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:15073157] synonym: "activation of neural crest cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of neural crest cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of neural crest cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905292 ! regulation of neural crest cell differentiation is_a: GO:2000738 ! positive regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0014033 ! neural crest cell differentiation relationship: positively_regulates GO:0014033 ! neural crest cell differentiation created_by: rl creation_date: 2016-06-28T15:02:16Z [Term] id: GO:1905298 name: regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] is_a: GO:0030856 ! regulation of epithelial cell differentiation is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060576 ! intestinal epithelial cell development relationship: regulates GO:0060576 ! intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:40:47Z [Term] id: GO:1905299 name: negative regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "down regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "down-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "downregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "inhibition of intestinal epithelial cell development" NARROW [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060576 ! intestinal epithelial cell development relationship: negatively_regulates GO:0060576 ! intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:40:55Z [Term] id: GO:1905300 name: positive regulation of intestinal epithelial cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23904268] synonym: "activation of intestinal epithelial cell development" NARROW [GOC:TermGenie] synonym: "up regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "up-regulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] synonym: "upregulation of intestinal epithelial cell development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905298 ! regulation of intestinal epithelial cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060576 ! intestinal epithelial cell development relationship: positively_regulates GO:0060576 ! intestinal epithelial cell development created_by: rph creation_date: 2016-06-30T11:41:02Z [Term] id: GO:1905304 name: regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "regulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0060284 ! regulation of cell development is_a: GO:0110020 ! regulation of actomyosin structure organization is_a: GO:1902115 ! regulation of organelle assembly is_a: GO:1902903 ! regulation of supramolecular fiber organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055003 ! cardiac myofibril assembly relationship: regulates GO:0055003 ! cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:01:49Z [Term] id: GO:1905305 name: negative regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "down regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "downregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "inhibition of cardiac myofibril assembly" NARROW [GOC:TermGenie] synonym: "inhibition of cardiac myofibril development" NARROW [GOC:TermGenie] synonym: "inhibition of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "negative regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0051494 ! negative regulation of cytoskeleton organization is_a: GO:1902116 ! negative regulation of organelle assembly is_a: GO:1902904 ! negative regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly is_a: GO:2000726 ! negative regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055003 ! cardiac myofibril assembly relationship: negatively_regulates GO:0055003 ! cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:01:58Z [Term] id: GO:1905306 name: positive regulation of cardiac myofibril assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:16151019] synonym: "activation of cardiac myofibril assembly" NARROW [GOC:TermGenie] synonym: "activation of cardiac myofibril development" NARROW [GOC:TermGenie] synonym: "activation of cardiac myofibril morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "positive regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "up regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of heart myofibril assembly" RELATED [GOC:TermGenie] synonym: "upregulation of cardiac myofibril assembly" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril development" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac myofibril morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of heart myofibril assembly" RELATED [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051495 ! positive regulation of cytoskeleton organization is_a: GO:1902117 ! positive regulation of organelle assembly is_a: GO:1902905 ! positive regulation of supramolecular fiber organization is_a: GO:1905304 ! regulation of cardiac myofibril assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055003 ! cardiac myofibril assembly relationship: positively_regulates GO:0055003 ! cardiac myofibril assembly created_by: rl creation_date: 2016-07-06T10:02:07Z [Term] id: GO:1905310 name: regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:26Z [Term] id: GO:1905311 name: negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: negatively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:35Z [Term] id: GO:1905312 name: positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:17628518] synonym: "activation of cardiac neural crest cell migration involved in outflow tract morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905310 ! regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis relationship: positively_regulates GO:0003253 ! cardiac neural crest cell migration involved in outflow tract morphogenesis created_by: rl creation_date: 2016-07-11T17:34:43Z [Term] id: GO:1905315 name: cell proliferation involved in endocardial cushion morphogenesis namespace: biological_process def: "Any cell proliferation that is involved in endocardial cushion morphogenesis." [GO_REF:0000060, GOC:BHF, GOC:rl, GOC:TermGenie, PMID:20652948] is_a: GO:0061323 ! cell proliferation involved in heart morphogenesis intersection_of: GO:0008283 ! cell population proliferation intersection_of: part_of GO:0003203 ! endocardial cushion morphogenesis relationship: part_of GO:0003203 ! endocardial cushion morphogenesis created_by: rl creation_date: 2016-07-12T13:56:36Z [Term] id: GO:1905319 name: mesenchymal stem cell migration namespace: biological_process def: "The orderly movement of a mesenchymal stem cell from one site to another." [GO_REF:0000091, GOC:TermGenie, PMID:24924806, PMID:25181476] is_a: GO:0016477 ! cell migration intersection_of: GO:0016477 ! cell migration intersection_of: results_in_movement_of CL:0000134 ! mesenchymal stem cell relationship: results_in_movement_of CL:0000134 ! mesenchymal stem cell created_by: sl creation_date: 2016-07-14T17:13:02Z [Term] id: GO:1905320 name: regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905319 ! mesenchymal stem cell migration relationship: regulates GO:1905319 ! mesenchymal stem cell migration created_by: sl creation_date: 2016-07-15T22:19:14Z [Term] id: GO:1905321 name: negative regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "down regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "down-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "downregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "inhibition of mesenchymal stem cell migration" NARROW [GOC:TermGenie] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905319 ! mesenchymal stem cell migration relationship: negatively_regulates GO:1905319 ! mesenchymal stem cell migration created_by: sl creation_date: 2016-07-15T22:19:22Z [Term] id: GO:1905322 name: positive regulation of mesenchymal stem cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration." [GO_REF:0000058, GOC:TermGenie, PMID:26846297] synonym: "activation of mesenchymal stem cell migration" NARROW [GOC:TermGenie] synonym: "up regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "up-regulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] synonym: "upregulation of mesenchymal stem cell migration" EXACT [GOC:TermGenie] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:1905320 ! regulation of mesenchymal stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905319 ! mesenchymal stem cell migration relationship: positively_regulates GO:1905319 ! mesenchymal stem cell migration created_by: sl creation_date: 2016-07-15T22:19:29Z [Term] id: GO:1905330 name: regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002009 ! morphogenesis of an epithelium relationship: regulates GO:0002009 ! morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:13:49Z [Term] id: GO:1905331 name: negative regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "down regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "down-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "downregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "inhibition of epithelium morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of morphogenesis of an epithelium" NARROW [GOC:TermGenie] synonym: "negative regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002009 ! morphogenesis of an epithelium relationship: negatively_regulates GO:0002009 ! morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:13:57Z [Term] id: GO:1905332 name: positive regulation of morphogenesis of an epithelium namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:25745997] comment: An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). synonym: "activation of epithelium morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of morphogenesis of an epithelium" NARROW [GOC:TermGenie] synonym: "positive regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "up-regulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] synonym: "upregulation of epithelium morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of morphogenesis of an epithelium" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002009 ! morphogenesis of an epithelium relationship: positively_regulates GO:0002009 ! morphogenesis of an epithelium created_by: bhm creation_date: 2016-07-22T07:14:05Z [Term] id: GO:1905349 name: ciliary transition zone assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone." [GO_REF:0000079, GOC:cilia, GOC:TermGenie, PMID:21725307, PMID:23644468, PMID:24448408, PMID:26595381, PMID:26982032] synonym: "cilial transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilial transition zone formation" EXACT [GOC:TermGenie] synonym: "ciliary transition zone formation" EXACT [GOC:TermGenie] synonym: "cilium transition zone assembly" EXACT [GOC:TermGenie] synonym: "cilium transition zone formation" EXACT [GOC:TermGenie] is_a: GO:0022607 ! cellular component assembly intersection_of: GO:0022607 ! cellular component assembly intersection_of: results_in_assembly_of GO:0035869 ! ciliary transition zone relationship: part_of GO:0060271 ! cilium assembly relationship: results_in_assembly_of GO:0035869 ! ciliary transition zone created_by: pr creation_date: 2016-08-04T14:49:43Z [Term] id: GO:1905383 name: protein localization to presynapse namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a presynapse." [GO_REF:0000087, GOC:TermGenie, PMID:24449494] synonym: "protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "recruitment of presynaptic proteins" EXACT [PMID:24449494] is_a: GO:0035418 ! protein localization to synapse intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0098793 ! presynapse relationship: has_target_end_location GO:0098793 ! presynapse created_by: dos creation_date: 2016-08-18T14:42:59Z [Term] id: GO:1905384 name: regulation of protein localization to presynapse namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902473 ! regulation of protein localization to synapse intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905383 ! protein localization to presynapse relationship: regulates GO:1905383 ! protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:00Z [Term] id: GO:1905385 name: negative regulation of protein localization to presynapse namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "down regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "down-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "downregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to presynapse" NARROW [GOC:TermGenie] synonym: "inhibition of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "negative regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905383 ! protein localization to presynapse relationship: negatively_regulates GO:1905383 ! protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:08Z [Term] id: GO:1905386 name: positive regulation of protein localization to presynapse namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:24449494] synonym: "activation of protein localisation in presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization in presynapse" NARROW [GOC:TermGenie] synonym: "activation of protein localization to presynapse" NARROW [GOC:TermGenie] synonym: "activation of recruitment of presynaptic proteins" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "positive regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "up-regulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to presynapse" EXACT [GOC:TermGenie] synonym: "upregulation of recruitment of presynaptic proteins" EXACT [GOC:TermGenie] is_a: GO:1902474 ! positive regulation of protein localization to synapse is_a: GO:1905384 ! regulation of protein localization to presynapse intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905383 ! protein localization to presynapse relationship: positively_regulates GO:1905383 ! protein localization to presynapse created_by: dos creation_date: 2016-08-18T14:56:21Z [Term] id: GO:1905427 name: intracellular signal transduction involved in positive regulation of cell growth namespace: biological_process def: "Any intracellular signal transduction that is involved in positive regulation of cell growth." [GO_REF:0000060, GOC:al, GOC:TermGenie, GOC:vw, PMID:15917811] synonym: "intracellular protein kinase cascade involved in activation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular protein kinase cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular protein kinase cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular protein kinase cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular protein kinase cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular protein kinase cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction involved in activation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction involved in stimulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction involved in up regulation of cell growth" EXACT [GOC:TermGenie] synonym: "intracellular signal transduction involved in up-regulation of cell growth" EXACT [GOC:TermGenie] synonym: "intracellular signal transduction involved in upregulation of cell growth" EXACT [GOC:TermGenie] synonym: "intracellular signal transduction pathway involved in activation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction pathway involved in positive regulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction pathway involved in stimulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction pathway involved in up regulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction pathway involved in up-regulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signal transduction pathway involved in upregulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signaling cascade involved in activation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling cascade involved in positive regulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling cascade involved in stimulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling cascade involved in up regulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling cascade involved in up-regulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling cascade involved in upregulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling chain involved in activation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signaling chain involved in positive regulation of cell growth" EXACT [GOC:TermGenie] synonym: "intracellular signaling chain involved in stimulation of cell growth" NARROW [GOC:TermGenie] synonym: "intracellular signaling chain involved in up regulation of cell growth" EXACT [GOC:TermGenie] synonym: "intracellular signaling chain involved in up-regulation of cell growth" EXACT [GOC:TermGenie] synonym: "intracellular signaling chain involved in upregulation of cell growth" EXACT [GOC:TermGenie] synonym: "intracellular signaling pathway involved in activation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling pathway involved in positive regulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling pathway involved in stimulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling pathway involved in up regulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling pathway involved in up-regulation of cell growth" RELATED [GOC:TermGenie] synonym: "intracellular signaling pathway involved in upregulation of cell growth" RELATED [GOC:TermGenie] synonym: "protein kinase cascade involved in activation of cell growth" NARROW [GOC:TermGenie] synonym: "protein kinase cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] synonym: "protein kinase cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] synonym: "protein kinase cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] synonym: "protein kinase cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] synonym: "protein kinase cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] synonym: "signal transduction via intracellular signaling cascade involved in activation of cell growth" RELATED [GOC:TermGenie] synonym: "signal transduction via intracellular signaling cascade involved in positive regulation of cell growth" RELATED [GOC:TermGenie] synonym: "signal transduction via intracellular signaling cascade involved in stimulation of cell growth" RELATED [GOC:TermGenie] synonym: "signal transduction via intracellular signaling cascade involved in up regulation of cell growth" RELATED [GOC:TermGenie] synonym: "signal transduction via intracellular signaling cascade involved in up-regulation of cell growth" RELATED [GOC:TermGenie] synonym: "signal transduction via intracellular signaling cascade involved in upregulation of cell growth" RELATED [GOC:TermGenie] synonym: "signal transmission via intracellular cascade involved in activation of cell growth" NARROW [GOC:TermGenie] synonym: "signal transmission via intracellular cascade involved in positive regulation of cell growth" NARROW [GOC:TermGenie] synonym: "signal transmission via intracellular cascade involved in stimulation of cell growth" NARROW [GOC:TermGenie] synonym: "signal transmission via intracellular cascade involved in up regulation of cell growth" NARROW [GOC:TermGenie] synonym: "signal transmission via intracellular cascade involved in up-regulation of cell growth" NARROW [GOC:TermGenie] synonym: "signal transmission via intracellular cascade involved in upregulation of cell growth" NARROW [GOC:TermGenie] is_a: GO:0035556 ! intracellular signal transduction intersection_of: GO:0035556 ! intracellular signal transduction intersection_of: part_of GO:0030307 ! positive regulation of cell growth relationship: part_of GO:0030307 ! positive regulation of cell growth created_by: dph creation_date: 2016-09-07T18:15:01Z [Term] id: GO:1905432 name: regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] is_a: GO:0099177 ! regulation of trans-synaptic signaling intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide relationship: regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:56:47Z [Term] id: GO:1905433 name: negative regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "down regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "down-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "downregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "inhibition of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] synonym: "inhibition of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] synonym: "negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] is_a: GO:0010648 ! negative regulation of cell communication is_a: GO:0023057 ! negative regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide relationship: negatively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:56:55Z [Term] id: GO:1905434 name: positive regulation of retrograde trans-synaptic signaling by neuropeptide namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide." [GO_REF:0000058, GOC:bf, GOC:PARL, GOC:TermGenie, PMID:19448629] synonym: "activation of retrograde trans-synaptic signaling by neuropeptide" NARROW [GOC:TermGenie] synonym: "positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling" RELATED [GOC:bf] synonym: "up regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "up-regulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] synonym: "upregulation of retrograde trans-synaptic signaling by neuropeptide" EXACT [GOC:TermGenie] is_a: GO:0010647 ! positive regulation of cell communication is_a: GO:0023056 ! positive regulation of signaling is_a: GO:1905432 ! regulation of retrograde trans-synaptic signaling by neuropeptide intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide relationship: positively_regulates GO:0099082 ! retrograde trans-synaptic signaling by neuropeptide created_by: bf creation_date: 2016-09-14T10:57:02Z [Term] id: GO:1905453 name: regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002318 ! myeloid progenitor cell differentiation relationship: regulates GO:0002318 ! myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:18Z [Term] id: GO:1905454 name: negative regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation relationship: negatively_regulates GO:0002318 ! myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:26Z [Term] id: GO:1905455 name: positive regulation of myeloid progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "activation of myeloid progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of myeloid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905453 ! regulation of myeloid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation relationship: positively_regulates GO:0002318 ! myeloid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:33Z [Term] id: GO:1905456 name: regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] is_a: GO:1901532 ! regulation of hematopoietic progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002320 ! lymphoid progenitor cell differentiation relationship: regulates GO:0002320 ! lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:40Z [Term] id: GO:1905457 name: negative regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "down regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] is_a: GO:1901533 ! negative regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation relationship: negatively_regulates GO:0002320 ! lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:48Z [Term] id: GO:1905458 name: positive regulation of lymphoid progenitor cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation." [GO_REF:0000058, GOC:TermGenie, PMID:27010503] synonym: "activation of lymphoid progenitor cell differentiation" NARROW [GOC:TermGenie] synonym: "up regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of lymphoid progenitor cell differentiation" EXACT [GOC:TermGenie] is_a: GO:1901534 ! positive regulation of hematopoietic progenitor cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation relationship: positively_regulates GO:0002320 ! lymphoid progenitor cell differentiation created_by: rz creation_date: 2016-09-16T12:32:55Z [Term] id: GO:1905459 name: regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034391 ! regulation of smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process relationship: regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:33:54Z [Term] id: GO:1905460 name: negative regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "down regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "down regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "down-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "down-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "downregulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "downregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "inhibition of VSMC apoptotic process" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "negative regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "negative regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034392 ! negative regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process relationship: negatively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:34:03Z [Term] id: GO:1905461 name: positive regulation of vascular associated smooth muscle cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:26493107] synonym: "activation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of vascular associated smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "activation of vascular smooth muscle cell apoptotic process" NARROW [GOC:TermGenie] synonym: "activation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "activation of VSMC apoptotic process" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "positive regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "positive regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "up regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "up-regulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "up-regulation of VSMC apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of vascular associated smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of vascular smooth muscle cell apoptotic process" EXACT [GOC:TermGenie] synonym: "upregulation of VSMC apoptosis" NARROW [GOC:TermGenie] synonym: "upregulation of VSMC apoptotic process" EXACT [GOC:TermGenie] is_a: GO:0034393 ! positive regulation of smooth muscle cell apoptotic process is_a: GO:1905459 ! regulation of vascular associated smooth muscle cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process relationship: positively_regulates GO:1905288 ! vascular associated smooth muscle cell apoptotic process created_by: rph creation_date: 2016-09-19T11:34:10Z [Term] id: GO:1905475 name: regulation of protein localization to membrane namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072657 ! protein localization to membrane relationship: regulates GO:0072657 ! protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:03Z [Term] id: GO:1905476 name: negative regulation of protein localization to membrane namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "down regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in membrane" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to membrane" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in membrane" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072657 ! protein localization to membrane relationship: negatively_regulates GO:0072657 ! protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:10Z [Term] id: GO:1905477 name: positive regulation of protein localization to membrane namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to membrane." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:26911690] synonym: "activation of protein localisation in membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization in membrane" NARROW [GOC:TermGenie] synonym: "activation of protein localization to membrane" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in membrane" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to membrane" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905475 ! regulation of protein localization to membrane intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072657 ! protein localization to membrane relationship: positively_regulates GO:0072657 ! protein localization to membrane created_by: bc creation_date: 2016-09-21T16:20:18Z [Term] id: GO:1905483 name: regulation of motor neuron migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097475 ! motor neuron migration relationship: regulates GO:0097475 ! motor neuron migration created_by: hbye creation_date: 2016-09-23T12:49:54Z [Term] id: GO:1905484 name: negative regulation of motor neuron migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "down regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "down-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "downregulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "inhibition of motor neuron migration" NARROW [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001223 ! negative regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097475 ! motor neuron migration relationship: negatively_regulates GO:0097475 ! motor neuron migration created_by: hbye creation_date: 2016-09-23T12:50:11Z [Term] id: GO:1905485 name: positive regulation of motor neuron migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motor neuron migration." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "activation of motor neuron migration" NARROW [GOC:TermGenie] synonym: "up regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "up-regulation of motor neuron migration" EXACT [GOC:TermGenie] synonym: "upregulation of motor neuron migration" EXACT [GOC:TermGenie] is_a: GO:1905483 ! regulation of motor neuron migration is_a: GO:2001224 ! positive regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097475 ! motor neuron migration relationship: positively_regulates GO:0097475 ! motor neuron migration created_by: hbye creation_date: 2016-09-23T12:50:19Z [Term] id: GO:1905492 name: positive regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve." [GO_REF:0000058, GOC:TermGenie, PMID:16516839] synonym: "activation of branching morphogenesis of a nerve" NARROW [GOC:TermGenie] synonym: "up regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "up-regulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] synonym: "upregulation of branching morphogenesis of a nerve" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048755 ! branching morphogenesis of a nerve relationship: positively_regulates GO:0048755 ! branching morphogenesis of a nerve created_by: hbye creation_date: 2016-09-23T14:11:52Z [Term] id: GO:1905503 name: regulation of motile cilium assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "regulation of motile primary cilium assembly" RELATED [] synonym: "regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "regulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:1902017 ! regulation of cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044458 ! motile cilium assembly relationship: regulates GO:0044458 ! motile cilium assembly created_by: krc creation_date: 2016-09-27T18:27:47Z [Term] id: GO:1905504 name: negative regulation of motile cilium assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "down regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "down regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "down regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "down regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "down-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "down-regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "downregulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "downregulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "downregulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "inhibition of motile primary cilia assembly" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilia formation" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilium assembly" NARROW [GOC:TermGenie] synonym: "inhibition of motile primary cilium formation" NARROW [GOC:TermGenie] synonym: "inhibition of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "inhibition of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "negative regulation of motile primary cilium assembly" RELATED [] synonym: "negative regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "negative regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "negative regulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:1902018 ! negative regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044458 ! motile cilium assembly relationship: negatively_regulates GO:0044458 ! motile cilium assembly created_by: krc creation_date: 2016-09-27T18:27:55Z [Term] id: GO:1905505 name: positive regulation of motile cilium assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motile cilium assembly." [GO_REF:0000058, GOC:cilia, GOC:krc, GOC:TermGenie, PMID:25294941] synonym: "activation of motile primary cilia assembly" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilia formation" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilium assembly" NARROW [GOC:TermGenie] synonym: "activation of motile primary cilium formation" NARROW [GOC:TermGenie] synonym: "activation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "activation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "positive regulation of motile primary cilium assembly" RELATED [] synonym: "positive regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "positive regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "positive regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "up regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "up regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "up regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "up-regulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "up-regulation of nodal cilium formation" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilia assembly" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilia formation" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilium assembly" RELATED [GOC:TermGenie] synonym: "upregulation of motile primary cilium formation" RELATED [GOC:TermGenie] synonym: "upregulation of nodal cilium assembly" RELATED [GOC:TermGenie] synonym: "upregulation of nodal cilium formation" RELATED [GOC:TermGenie] is_a: GO:0045724 ! positive regulation of cilium assembly is_a: GO:1905503 ! regulation of motile cilium assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044458 ! motile cilium assembly relationship: positively_regulates GO:0044458 ! motile cilium assembly created_by: krc creation_date: 2016-09-27T18:28:03Z [Term] id: GO:1905516 name: positive regulation of fertilization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fertilization." [GO_REF:0000058, GOC:hbye, GOC:TermGenie, PMID:27564576] synonym: "activation of fertilization" NARROW [GOC:TermGenie] synonym: "activation of syngamy" NARROW [GOC:TermGenie] synonym: "positive regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up regulation of syngamy" EXACT [GOC:TermGenie] synonym: "up-regulation of fertilization" EXACT [GOC:TermGenie] synonym: "up-regulation of syngamy" EXACT [GOC:TermGenie] synonym: "upregulation of fertilization" EXACT [GOC:TermGenie] synonym: "upregulation of syngamy" EXACT [GOC:TermGenie] is_a: GO:0080154 ! regulation of fertilization is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0009566 ! fertilization relationship: positively_regulates GO:0009566 ! fertilization created_by: pr creation_date: 2016-09-30T14:32:32Z [Term] id: GO:1905553 name: regulation of blood vessel branching namespace: biological_process def: "Any process that modulates the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0045765 ! regulation of angiogenesis is_a: GO:0060688 ! regulation of morphogenesis of a branching structure is_a: GO:1905330 ! regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001569 ! branching involved in blood vessel morphogenesis relationship: regulates GO:0001569 ! branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:33Z [Term] id: GO:1905554 name: negative regulation of vessel branching namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "down-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "downregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "inhibition of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "negative regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0016525 ! negative regulation of angiogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis relationship: negatively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:41Z [Term] id: GO:1905555 name: positive regulation of blood vessel branching namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of blood vessel branching." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "activation of branching involved in blood vessel morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of patterning of blood vessels" NARROW [GOC:TermGenie] synonym: "positive regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "up-regulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of patterning of blood vessels" EXACT [GOC:TermGenie] synonym: "upregulation of branching involved in blood vessel morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of patterning of blood vessels" EXACT [GOC:TermGenie] is_a: GO:0045766 ! positive regulation of angiogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium is_a: GO:1905553 ! regulation of blood vessel branching intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis relationship: positively_regulates GO:0001569 ! branching involved in blood vessel morphogenesis created_by: nc creation_date: 2016-10-12T14:19:49Z [Term] id: GO:1905557 name: regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010549 ! regulation of membrane disassembly is_a: GO:0010564 ! regulation of cell cycle process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007077 ! mitotic nuclear membrane disassembly relationship: regulates GO:0007077 ! mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:14:57Z [Term] id: GO:1905558 name: negative regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "down regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "down-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "downregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] synonym: "inhibition of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] is_a: GO:0010948 ! negative regulation of cell cycle process is_a: GO:0051129 ! negative regulation of cellular component organization is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007077 ! mitotic nuclear membrane disassembly relationship: negatively_regulates GO:0007077 ! mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:15:08Z [Term] id: GO:1905559 name: positive regulation of mitotic nuclear envelope disassembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." [GO_REF:0000058, GOC:TermGenie, PMID:18765790] synonym: "activation of mitotic nuclear envelope breakdown" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope catabolism" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope degradation" NARROW [GOC:TermGenie] synonym: "activation of mitotic nuclear envelope disassembly" NARROW [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "up-regulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope breakdown" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope catabolism" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope degradation" EXACT [GOC:TermGenie] synonym: "upregulation of mitotic nuclear envelope disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:0090068 ! positive regulation of cell cycle process is_a: GO:1905557 ! regulation of mitotic nuclear envelope disassembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007077 ! mitotic nuclear membrane disassembly relationship: positively_regulates GO:0007077 ! mitotic nuclear membrane disassembly created_by: hbye creation_date: 2016-10-14T13:15:17Z [Term] id: GO:1905562 name: regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] is_a: GO:0001936 ! regulation of endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0101023 ! vascular endothelial cell proliferation relationship: regulates GO:0101023 ! vascular endothelial cell proliferation created_by: nc creation_date: 2016-10-17T09:24:17Z [Term] id: GO:1905563 name: negative regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "down regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0001937 ! negative regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation relationship: negatively_regulates GO:0101023 ! vascular endothelial cell proliferation created_by: nc creation_date: 2016-10-17T09:24:26Z [Term] id: GO:1905564 name: positive regulation of vascular endothelial cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation." [GO_REF:0000058, GOC:BHF, GOC:BHF_telomere, GOC:nc, GOC:TermGenie, PMID:23201774] synonym: "activation of vascular endothelial cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of vascular endothelial cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0001938 ! positive regulation of endothelial cell proliferation is_a: GO:1905562 ! regulation of vascular endothelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0101023 ! vascular endothelial cell proliferation relationship: positively_regulates GO:0101023 ! vascular endothelial cell proliferation created_by: nc creation_date: 2016-10-17T09:24:35Z [Term] id: GO:1905606 name: regulation of presynapse assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] subset: goslim_synapse synonym: "regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051963 ! regulation of synapse assembly is_a: GO:0099174 ! regulation of presynapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0099054 ! presynapse assembly relationship: regulates GO:0099054 ! presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:13Z [Term] id: GO:1905607 name: negative regulation of presynapse assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "down regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "down-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "downregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "inhibition of presynapse assembly" NARROW [GOC:TermGenie] synonym: "inhibition of presynapse biogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of presynaptic terminal assembly" NARROW [GOC:TermGenie] synonym: "negative regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051964 ! negative regulation of synapse assembly is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0099054 ! presynapse assembly relationship: negatively_regulates GO:0099054 ! presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:20Z [Term] id: GO:1905608 name: positive regulation of presynapse assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of presynapse assembly." [GO_REF:0000058, GOC:bc, GOC:PARL, GOC:TermGenie, PMID:25533483] synonym: "activation of presynapse assembly" NARROW [GOC:TermGenie] synonym: "activation of presynapse biogenesis" NARROW [GOC:TermGenie] synonym: "activation of presynaptic terminal assembly" NARROW [GOC:TermGenie] synonym: "positive regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "up-regulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse assembly" EXACT [GOC:TermGenie] synonym: "upregulation of presynapse biogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of presynaptic terminal assembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905606 ! regulation of presynapse assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0099054 ! presynapse assembly relationship: positively_regulates GO:0099054 ! presynapse assembly created_by: bc creation_date: 2016-10-27T16:08:28Z [Term] id: GO:1905627 name: regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009889 ! regulation of biosynthetic process is_a: GO:0031323 ! regulation of cellular metabolic process is_a: GO:0051171 ! regulation of nitrogen compound metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0042427 ! serotonin biosynthetic process relationship: regulates GO:0042427 ! serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:20Z [Term] id: GO:1905628 name: negative regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "down regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "down-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "downregulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of serotonin anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin formation" NARROW [GOC:TermGenie] synonym: "inhibition of serotonin synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "negative regulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009890 ! negative regulation of biosynthetic process is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:0051172 ! negative regulation of nitrogen compound metabolic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0042427 ! serotonin biosynthetic process relationship: negatively_regulates GO:0042427 ! serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:28Z [Term] id: GO:1905629 name: positive regulation of serotonin biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID:25642596] synonym: "activation of serotonin anabolism" NARROW [GOC:TermGenie] synonym: "activation of serotonin biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of serotonin biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of serotonin formation" NARROW [GOC:TermGenie] synonym: "activation of serotonin synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "positive regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "up-regulation of serotonin synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin formation" EXACT [GOC:TermGenie] synonym: "upregulation of serotonin synthesis" EXACT [GOC:TermGenie] is_a: GO:0009891 ! positive regulation of biosynthetic process is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:0051173 ! positive regulation of nitrogen compound metabolic process is_a: GO:1905627 ! regulation of serotonin biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0042427 ! serotonin biosynthetic process relationship: positively_regulates GO:0042427 ! serotonin biosynthetic process created_by: pad creation_date: 2016-10-31T14:26:36Z [Term] id: GO:1905634 name: regulation of protein localization to chromatin namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to chromatin." [GO_REF:0000058, GOC:TermGenie, PMID:20889714] synonym: "regulation of protein localisation to chromatin" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071168 ! protein localization to chromatin relationship: regulates GO:0071168 ! protein localization to chromatin created_by: pga creation_date: 2016-11-01T16:33:52Z [Term] id: GO:1905651 name: regulation of artery morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048844 ! artery morphogenesis relationship: regulates GO:0048844 ! artery morphogenesis created_by: rph creation_date: 2016-11-09T12:19:37Z [Term] id: GO:1905652 name: negative regulation of artery morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "down regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of arterial morphogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of arteriogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of artery morphogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "negative regulation of arteriogenesis" EXACT [GOC:TermGenie] is_a: GO:1905651 ! regulation of artery morphogenesis is_a: GO:2000181 ! negative regulation of blood vessel morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048844 ! artery morphogenesis relationship: negatively_regulates GO:0048844 ! artery morphogenesis created_by: rph creation_date: 2016-11-09T12:19:53Z [Term] id: GO:1905653 name: positive regulation of artery morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of artery morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:27389411] synonym: "activation of arterial morphogenesis" NARROW [GOC:TermGenie] synonym: "activation of arteriogenesis" NARROW [GOC:TermGenie] synonym: "activation of artery morphogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "positive regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of artery morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arterial morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of arteriogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of artery morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:1905651 ! regulation of artery morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048844 ! artery morphogenesis relationship: positively_regulates GO:0048844 ! artery morphogenesis created_by: rph creation_date: 2016-11-09T12:20:01Z [Term] id: GO:1905690 name: nucleus disassembly namespace: biological_process def: "The disaggregation of a nucleus into its constituent components." [GO_REF:0000079, GOC:autophagy, GOC:pr, GOC:TermGenie] synonym: "cell nucleus disassembly" EXACT [GOC:TermGenie] is_a: GO:0006997 ! nucleus organization is_a: GO:1903008 ! organelle disassembly intersection_of: GO:0022411 ! cellular component disassembly intersection_of: results_in_disassembly_of GO:0005634 ! nucleus relationship: results_in_disassembly_of GO:0005634 ! nucleus created_by: pr creation_date: 2016-11-14T13:38:57Z [Term] id: GO:1905720 name: cytoplasmic microtubule bundle namespace: cellular_component def: "Any microtubule bundle that is part of a cytoplasm." [GO_REF:0000064, GOC:TermGenie, PMID:11007487, PMID:26124291] synonym: "microtubule bundle of cytoplasm" EXACT [GOC:TermGenie] synonym: "microtubule fascicle of cytoplasm" EXACT [GOC:TermGenie] is_a: GO:0097427 ! microtubule bundle intersection_of: GO:0097427 ! microtubule bundle intersection_of: part_of GO:0005737 ! cytoplasm relationship: part_of GO:0005737 ! cytoplasm created_by: mah creation_date: 2016-11-24T16:52:02Z [Term] id: GO:1905748 name: hard palate morphogenesis namespace: biological_process def: "The developmental process by which a hard palate is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:23419067] synonym: "palatum durum morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0009653 ! anatomical structure morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003216 ! hard palate relationship: results_in_morphogenesis_of UBERON:0003216 ! hard palate created_by: pga creation_date: 2016-12-09T12:22:24Z [Term] id: GO:1905755 name: protein localization to cytoplasmic microtubule namespace: biological_process def: "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule." [GO_REF:0000087, GOC:TermGenie, PMID:15177031] synonym: "protein localisation to cytoplasmic microtubule" EXACT [GOC:TermGenie] is_a: GO:0035372 ! protein localization to microtubule intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0005881 ! cytoplasmic microtubule relationship: has_target_end_location GO:0005881 ! cytoplasmic microtubule created_by: mah creation_date: 2016-12-12T15:31:07Z [Term] id: GO:1905770 name: regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048333 ! mesodermal cell differentiation relationship: regulates GO:0048333 ! mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:13Z [Term] id: GO:1905771 name: negative regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "down regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "downregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "inhibition of mesoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "inhibition of mesodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "negative regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048333 ! mesodermal cell differentiation relationship: negatively_regulates GO:0048333 ! mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:23Z [Term] id: GO:1905772 name: positive regulation of mesodermal cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23765923] synonym: "activation of mesoderm cell differentiation" NARROW [GOC:TermGenie] synonym: "activation of mesodermal cell differentiation" NARROW [GOC:TermGenie] synonym: "positive regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm cell differentiation" EXACT [GOC:TermGenie] synonym: "upregulation of mesodermal cell differentiation" EXACT [GOC:TermGenie] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:1905770 ! regulation of mesodermal cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048333 ! mesodermal cell differentiation relationship: positively_regulates GO:0048333 ! mesodermal cell differentiation created_by: rph creation_date: 2016-12-21T12:44:32Z [Term] id: GO:1905787 name: regulation of detection of mechanical stimulus involved in sensory perception of touch namespace: biological_process def: "Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] synonym: "regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] is_a: GO:0032101 ! regulation of response to external stimulus is_a: GO:0051931 ! regulation of sensory perception intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch relationship: regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch created_by: hbye creation_date: 2017-01-09T15:11:04Z [Term] id: GO:1905788 name: negative regulation of detection of mechanical stimulus involved in sensory perception of touch namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] synonym: "down regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "down regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "down-regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down-regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "down-regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "downregulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "downregulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "downregulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "downregulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "inhibition of detection of mechanical stimulus involved in sensory perception of touch" NARROW [GOC:TermGenie] synonym: "inhibition of perception of touch, detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "inhibition of perception of touch, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "inhibition of perception of touch, sensory transduction of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "inhibition of sensory detection of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "inhibition of sensory transduction of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "inhibition of tactition, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "negative regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "negative regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "negative regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "negative regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "negative regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "negative regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] is_a: GO:0031645 ! negative regulation of nervous system process is_a: GO:0032102 ! negative regulation of response to external stimulus is_a: GO:1905787 ! regulation of detection of mechanical stimulus involved in sensory perception of touch intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch relationship: negatively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch created_by: hbye creation_date: 2017-01-09T15:11:14Z [Term] id: GO:1905789 name: positive regulation of detection of mechanical stimulus involved in sensory perception of touch namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch." [GO_REF:0000058, GOC:TermGenie, PMID:8692859] synonym: "activation of detection of mechanical stimulus involved in sensory perception of touch" NARROW [GOC:TermGenie] synonym: "activation of perception of touch, detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "activation of perception of touch, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "activation of perception of touch, sensory transduction of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "activation of sensory detection of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "activation of sensory transduction of mechanical stimulus during perception of touch" NARROW [GOC:TermGenie] synonym: "activation of tactition, sensory detection of mechanical stimulus" NARROW [GOC:TermGenie] synonym: "positive regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "positive regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "positive regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "positive regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "positive regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "positive regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "up regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "up-regulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up-regulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "up-regulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of detection of mechanical stimulus involved in sensory perception of touch" EXACT [GOC:TermGenie] synonym: "upregulation of perception of touch, detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of perception of touch, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of perception of touch, sensory transduction of mechanical stimulus" EXACT [GOC:TermGenie] synonym: "upregulation of sensory detection of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "upregulation of sensory transduction of mechanical stimulus during perception of touch" EXACT [GOC:TermGenie] synonym: "upregulation of tactition, sensory detection of mechanical stimulus" EXACT [GOC:TermGenie] is_a: GO:0031646 ! positive regulation of nervous system process is_a: GO:0032103 ! positive regulation of response to external stimulus is_a: GO:1905787 ! regulation of detection of mechanical stimulus involved in sensory perception of touch intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch relationship: positively_regulates GO:0050976 ! detection of mechanical stimulus involved in sensory perception of touch created_by: hbye creation_date: 2017-01-09T15:11:23Z [Term] id: GO:1905806 name: regulation of synapse pruning namespace: biological_process def: "Any process that modulates the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] subset: goslim_synapse synonym: "regulation of synapse clearance" EXACT [] synonym: "regulation of synapse disassembly" EXACT syngo_official_label [] synonym: "regulation of synapse elimination" EXACT [] synonym: "regulation of synapse removal" EXACT [] is_a: GO:0050807 ! regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0098883 ! synapse pruning relationship: regulates GO:0098883 ! synapse pruning created_by: tb creation_date: 2017-01-11T22:03:15Z [Term] id: GO:1905807 name: negative regulation of synapse pruning namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "downregulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "inhibition of synapse disassembly" NARROW [GOC:TermGenie] synonym: "regulation of synapse clearance" BROAD [] synonym: "regulation of synapse disassembly" BROAD [] synonym: "regulation of synapse elimination" BROAD [] synonym: "regulation of synapse removal" BROAD [] is_a: GO:1905806 ! regulation of synapse pruning is_a: GO:1905809 ! negative regulation of synapse organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0098883 ! synapse pruning relationship: negatively_regulates GO:0098883 ! synapse pruning created_by: tb creation_date: 2017-01-11T22:03:24Z [Term] id: GO:1905808 name: positive regulation of synapse pruning namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of synapse pruning." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "activation of synapse disassembly" NARROW [GOC:TermGenie] synonym: "regulation of synapse clearance" BROAD [] synonym: "regulation of synapse disassembly" BROAD [] synonym: "regulation of synapse elimination" BROAD [] synonym: "regulation of synapse removal" BROAD [] synonym: "up regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "up-regulation of synapse disassembly" EXACT [GOC:TermGenie] synonym: "upregulation of synapse disassembly" EXACT [GOC:TermGenie] is_a: GO:0051130 ! positive regulation of cellular component organization is_a: GO:1905806 ! regulation of synapse pruning intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0098883 ! synapse pruning relationship: positively_regulates GO:0098883 ! synapse pruning created_by: tb creation_date: 2017-01-11T22:03:33Z [Term] id: GO:1905809 name: negative regulation of synapse organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." [GO_REF:0000058, GOC:TermGenie, PMID:27779093] synonym: "down regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "down regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "down regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of synapse development" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "down-regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organization" EXACT [GOC:TermGenie] synonym: "down-regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of synapse development" EXACT [GOC:TermGenie] synonym: "downregulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "downregulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organization" EXACT [GOC:TermGenie] synonym: "downregulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of synapse development" NARROW [GOC:TermGenie] synonym: "inhibition of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "inhibition of synapse organisation" NARROW [GOC:TermGenie] synonym: "inhibition of synapse organization" NARROW [GOC:TermGenie] synonym: "inhibition of synapse organization and biogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of synapse development" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse morphogenesis" RELATED [GOC:TermGenie] synonym: "negative regulation of synapse organisation" EXACT [GOC:TermGenie] synonym: "negative regulation of synapse organization and biogenesis" RELATED [GOC:TermGenie] is_a: GO:0050807 ! regulation of synapse organization is_a: GO:0051129 ! negative regulation of cellular component organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0050808 ! synapse organization relationship: negatively_regulates GO:0050808 ! synapse organization created_by: tb creation_date: 2017-01-11T22:03:41Z [Term] id: GO:1905821 name: positive regulation of chromosome condensation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome condensation." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:17268547] synonym: "activation of chromosome condensation" NARROW [GOC:TermGenie] synonym: "activation of eukaryotic chromosome condensation" NARROW [GOC:TermGenie] synonym: "activation of nuclear chromosome condensation" NARROW [GOC:TermGenie] synonym: "positive regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "positive regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "up-regulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of eukaryotic chromosome condensation" EXACT [GOC:TermGenie] synonym: "upregulation of nuclear chromosome condensation" EXACT [GOC:TermGenie] is_a: GO:0060623 ! regulation of chromosome condensation is_a: GO:2001252 ! positive regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030261 ! chromosome condensation relationship: positively_regulates GO:0030261 ! chromosome condensation created_by: bhm creation_date: 2017-01-13T14:13:44Z [Term] id: GO:1905833 name: negative regulation of microtubule nucleation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." [GO_REF:0000058, GOC:TermGenie, PMID:27689799] synonym: "down regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "down-regulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "downregulation of microtubule nucleation" EXACT [GOC:TermGenie] synonym: "inhibition of microtubule nucleation" NARROW [GOC:TermGenie] is_a: GO:0010968 ! regulation of microtubule nucleation is_a: GO:0031115 ! negative regulation of microtubule polymerization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007020 ! microtubule nucleation relationship: negatively_regulates GO:0007020 ! microtubule nucleation created_by: hbye creation_date: 2017-01-17T12:00:56Z [Term] id: GO:1905867 name: epididymis development namespace: biological_process def: "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure." [GO_REF:0000094, GOC:TermGenie, PMID:12388089] synonym: "epididymus development" EXACT [GOC:TermGenie] is_a: GO:0035295 ! tube development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0001301 ! epididymis relationship: results_in_development_of UBERON:0001301 ! epididymis created_by: sl creation_date: 2017-01-27T00:00:33Z [Term] id: GO:1905871 name: regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:0032880 ! regulation of protein localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:1902463 ! protein localization to cell leading edge relationship: regulates GO:1902463 ! protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:34:55Z [Term] id: GO:1905872 name: negative regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "down regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "down-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "downregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "inhibition of protein localisation in cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localisation to cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization in cell leading edge" NARROW [GOC:TermGenie] synonym: "inhibition of protein localization to cell leading edge" NARROW [GOC:TermGenie] synonym: "negative regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "negative regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903828 ! negative regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:1902463 ! protein localization to cell leading edge relationship: negatively_regulates GO:1902463 ! protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:35:04Z [Term] id: GO:1905873 name: positive regulation of protein localization to cell leading edge namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge." [GO_REF:0000058, GOC:TermGenie, PMID:26324884] synonym: "activation of protein localisation in cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localisation to cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localization in cell leading edge" NARROW [GOC:TermGenie] synonym: "activation of protein localization to cell leading edge" NARROW [GOC:TermGenie] synonym: "positive regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "positive regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "up-regulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localisation to cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization in cell leading edge" EXACT [GOC:TermGenie] synonym: "upregulation of protein localization to cell leading edge" EXACT [GOC:TermGenie] is_a: GO:1903829 ! positive regulation of protein localization is_a: GO:1905871 ! regulation of protein localization to cell leading edge intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:1902463 ! protein localization to cell leading edge relationship: positively_regulates GO:1902463 ! protein localization to cell leading edge created_by: sl creation_date: 2017-01-27T19:35:13Z [Term] id: GO:1905879 name: regulation of oogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:0060284 ! regulation of cell development is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048477 ! oogenesis relationship: regulates GO:0048477 ! oogenesis created_by: hbye creation_date: 2017-01-31T09:31:05Z [Term] id: GO:1905880 name: negative regulation of oogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "down regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down regulation of ovum development" EXACT [GOC:TermGenie] synonym: "down-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "downregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of ovum development" EXACT [GOC:TermGenie] synonym: "inhibition of oogenesis" NARROW [GOC:TermGenie] synonym: "inhibition of ovum development" NARROW [GOC:TermGenie] synonym: "negative regulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048477 ! oogenesis relationship: negatively_regulates GO:0048477 ! oogenesis created_by: hbye creation_date: 2017-01-31T09:31:15Z [Term] id: GO:1905881 name: positive regulation of oogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oogenesis." [GO_REF:0000058, GOC:TermGenie, PMID:26434723] synonym: "activation of oogenesis" NARROW [GOC:TermGenie] synonym: "activation of ovum development" NARROW [GOC:TermGenie] synonym: "positive regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of ovum development" EXACT [GOC:TermGenie] synonym: "up-regulation of oogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of ovum development" EXACT [GOC:TermGenie] synonym: "upregulation of oogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of ovum development" EXACT [GOC:TermGenie] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905879 ! regulation of oogenesis is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048477 ! oogenesis relationship: positively_regulates GO:0048477 ! oogenesis created_by: hbye creation_date: 2017-01-31T09:31:23Z [Term] id: GO:1905899 name: regulation of smooth muscle tissue development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] is_a: GO:1901861 ! regulation of muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048745 ! smooth muscle tissue development relationship: regulates GO:0048745 ! smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:16Z [Term] id: GO:1905900 name: negative regulation of smooth muscle tissue development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "down regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "down-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "downregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "inhibition of smooth muscle tissue development" NARROW [GOC:TermGenie] is_a: GO:1901862 ! negative regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048745 ! smooth muscle tissue development relationship: negatively_regulates GO:0048745 ! smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:24Z [Term] id: GO:1905901 name: positive regulation of smooth muscle tissue development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development." [GO_REF:0000058, GOC:bhm, GOC:TermGenie, PMID:14709716] synonym: "activation of smooth muscle tissue development" NARROW [GOC:TermGenie] synonym: "up regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "up-regulation of smooth muscle tissue development" EXACT [GOC:TermGenie] synonym: "upregulation of smooth muscle tissue development" EXACT [GOC:TermGenie] is_a: GO:1901863 ! positive regulation of muscle tissue development is_a: GO:1905899 ! regulation of smooth muscle tissue development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048745 ! smooth muscle tissue development relationship: positively_regulates GO:0048745 ! smooth muscle tissue development created_by: bhm creation_date: 2017-02-01T14:31:33Z [Term] id: GO:1905902 name: regulation of mesoderm formation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001707 ! mesoderm formation relationship: regulates GO:0001707 ! mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:20Z [Term] id: GO:1905903 name: negative regulation of mesoderm formation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "down regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "down-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "downregulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "inhibition of mesoderm formation" NARROW [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000381 ! negative regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001707 ! mesoderm formation relationship: negatively_regulates GO:0001707 ! mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:29Z [Term] id: GO:1905904 name: positive regulation of mesoderm formation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm formation." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:23939491] synonym: "activation of mesoderm formation" NARROW [GOC:TermGenie] synonym: "up regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "up-regulation of mesoderm formation" EXACT [GOC:TermGenie] synonym: "upregulation of mesoderm formation" EXACT [GOC:TermGenie] is_a: GO:1905902 ! regulation of mesoderm formation is_a: GO:2000382 ! positive regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001707 ! mesoderm formation relationship: positively_regulates GO:0001707 ! mesoderm formation created_by: rph creation_date: 2017-02-03T12:28:38Z [Term] id: GO:1905905 name: pharyngeal gland morphogenesis namespace: biological_process def: "The developmental process by which a pharyngeal gland is generated and organized." [GO_REF:0000083, GOC:TermGenie, PMID:21868609] synonym: "glandulae pharyngeae morphogenesis" RELATED [GOC:TermGenie] synonym: "pharynx gland morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0022612 ! gland morphogenesis intersection_of: GO:0009653 ! anatomical structure morphogenesis intersection_of: results_in_morphogenesis_of UBERON:0003295 ! pharyngeal gland relationship: results_in_morphogenesis_of UBERON:0003295 ! pharyngeal gland created_by: rz creation_date: 2017-02-03T14:39:10Z [Term] id: GO:1905921 name: regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0060408 ! regulation of acetylcholine metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008292 ! acetylcholine biosynthetic process relationship: regulates GO:0008292 ! acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:30Z [Term] id: GO:1905922 name: negative regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "down regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "down-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "downregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "inhibition of acetylcholine anabolism" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine biosynthesis" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine formation" NARROW [GOC:TermGenie] synonym: "inhibition of acetylcholine synthesis" NARROW [GOC:TermGenie] synonym: "negative regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "negative regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0060410 ! negative regulation of acetylcholine metabolic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process relationship: negatively_regulates GO:0008292 ! acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:39Z [Term] id: GO:1905923 name: positive regulation of acetylcholine biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process." [GO_REF:0000058, GOC:aruk, GOC:bc, GOC:TermGenie, PMID:20164328] synonym: "activation of acetylcholine anabolism" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine biosynthesis" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine biosynthetic process" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine formation" NARROW [GOC:TermGenie] synonym: "activation of acetylcholine synthesis" NARROW [GOC:TermGenie] synonym: "positive regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "positive regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "up-regulation of acetylcholine synthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine anabolism" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthesis" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine biosynthetic process" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine formation" EXACT [GOC:TermGenie] synonym: "upregulation of acetylcholine synthesis" EXACT [GOC:TermGenie] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0060409 ! positive regulation of acetylcholine metabolic process is_a: GO:1905921 ! regulation of acetylcholine biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008292 ! acetylcholine biosynthetic process relationship: positively_regulates GO:0008292 ! acetylcholine biosynthetic process created_by: bc creation_date: 2017-02-08T13:08:48Z [Term] id: GO:1905936 name: regulation of germ cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] is_a: GO:0042127 ! regulation of cell population proliferation is_a: GO:0051239 ! regulation of multicellular organismal process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0036093 ! germ cell proliferation relationship: regulates GO:0036093 ! germ cell proliferation created_by: hbye creation_date: 2017-02-09T14:51:31Z [Term] id: GO:1905937 name: negative regulation of germ cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "down-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "downregulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "inhibition of germ cell proliferation" NARROW [GOC:TermGenie] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0036093 ! germ cell proliferation relationship: negatively_regulates GO:0036093 ! germ cell proliferation created_by: hbye creation_date: 2017-02-09T14:51:41Z [Term] id: GO:1905938 name: positive regulation of germ cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of germ cell proliferation." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "activation of germ cell proliferation" NARROW [GOC:TermGenie] synonym: "up regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "up-regulation of germ cell proliferation" EXACT [GOC:TermGenie] synonym: "upregulation of germ cell proliferation" EXACT [GOC:TermGenie] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905936 ! regulation of germ cell proliferation is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0036093 ! germ cell proliferation relationship: positively_regulates GO:0036093 ! germ cell proliferation created_by: hbye creation_date: 2017-02-09T14:51:51Z [Term] id: GO:1905939 name: regulation of gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0050793 ! regulation of developmental process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008406 ! gonad development relationship: regulates GO:0008406 ! gonad development created_by: hbye creation_date: 2017-02-09T17:01:50Z [Term] id: GO:1905940 name: negative regulation of gonad development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "down regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "down-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of gonad development" EXACT [GOC:TermGenie] synonym: "downregulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of gonad development" NARROW [GOC:TermGenie] synonym: "inhibition of gonadogenesis" NARROW [GOC:TermGenie] synonym: "negative regulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000242 ! negative regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008406 ! gonad development relationship: negatively_regulates GO:0008406 ! gonad development created_by: hbye creation_date: 2017-02-09T17:01:59Z [Term] id: GO:1905941 name: positive regulation of gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gonad development." [GO_REF:0000058, GOC:TermGenie, PMID:15342467] synonym: "activation of gonad development" NARROW [GOC:TermGenie] synonym: "activation of gonadogenesis" NARROW [GOC:TermGenie] synonym: "positive regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of gonad development" EXACT [GOC:TermGenie] synonym: "up-regulation of gonadogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of gonad development" EXACT [GOC:TermGenie] synonym: "upregulation of gonadogenesis" EXACT [GOC:TermGenie] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000243 ! positive regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008406 ! gonad development relationship: positively_regulates GO:0008406 ! gonad development created_by: hbye creation_date: 2017-02-09T17:02:08Z [Term] id: GO:1905952 name: regulation of lipid localization namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0032879 ! regulation of localization intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0010876 ! lipid localization relationship: regulates GO:0010876 ! lipid localization created_by: rz creation_date: 2017-02-21T12:12:22Z [Term] id: GO:1905953 name: negative regulation of lipid localization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "down regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "down-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "downregulation of lipid localization" EXACT [GOC:TermGenie] synonym: "inhibition of lipid localisation" NARROW [GOC:TermGenie] synonym: "inhibition of lipid localization" NARROW [GOC:TermGenie] synonym: "negative regulation of lipid localisation" EXACT [GOC:TermGenie] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0010876 ! lipid localization relationship: negatively_regulates GO:0010876 ! lipid localization created_by: rz creation_date: 2017-02-21T12:12:41Z [Term] id: GO:1905954 name: positive regulation of lipid localization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lipid localization." [GO_REF:0000058, GOC:TermGenie, PMID:17564681] synonym: "activation of lipid localisation" NARROW [GOC:TermGenie] synonym: "activation of lipid localization" NARROW [GOC:TermGenie] synonym: "positive regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "up-regulation of lipid localization" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localisation" EXACT [GOC:TermGenie] synonym: "upregulation of lipid localization" EXACT [GOC:TermGenie] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:1905952 ! regulation of lipid localization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0010876 ! lipid localization relationship: positively_regulates GO:0010876 ! lipid localization created_by: rz creation_date: 2017-02-21T12:12:49Z [Term] id: GO:1905955 name: negative regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "down regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "down-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "downregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "inhibition of endothelial tube morphogenesis" NARROW [GOC:TermGenie] is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905331 ! negative regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061154 ! endothelial tube morphogenesis relationship: negatively_regulates GO:0061154 ! endothelial tube morphogenesis created_by: rph creation_date: 2017-02-21T15:17:31Z [Term] id: GO:1905956 name: positive regulation of endothelial tube morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis." [GO_REF:0000058, GOC:BHF, GOC:BHF_miRNA, GOC:rph, GOC:TermGenie, PMID:25961718] synonym: "activation of endothelial tube morphogenesis" NARROW [GOC:TermGenie] synonym: "up regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "up-regulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] synonym: "upregulation of endothelial tube morphogenesis" EXACT [GOC:TermGenie] is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:1901509 ! regulation of endothelial tube morphogenesis is_a: GO:1905332 ! positive regulation of morphogenesis of an epithelium intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061154 ! endothelial tube morphogenesis relationship: positively_regulates GO:0061154 ! endothelial tube morphogenesis created_by: rph creation_date: 2017-02-21T15:17:39Z [Term] id: GO:1990009 name: retinal cell apoptotic process namespace: biological_process alt_id: GO:0046674 def: "Any apoptotic process in a retinal cell." [GOC:mtg_apoptosis, PMID:15558487, PMID:24664675] synonym: "induction of retinal programmed cell death" RELATED [] is_a: GO:0006915 ! apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0009004 ! retinal cell relationship: occurs_in CL:0009004 ! retinal cell created_by: pr creation_date: 2012-12-12T10:15:08Z [Term] id: GO:1990010 name: compound eye retinal cell apoptotic process namespace: biological_process def: "Any apoptotic process in a compound eye retinal cell." [GOC:mtg_apoptosis, PMID:12021768] is_a: GO:1990009 ! retinal cell apoptotic process intersection_of: GO:0006915 ! apoptotic process intersection_of: occurs_in CL:0009001 ! compound eye retinal cell relationship: occurs_in CL:0009001 ! compound eye retinal cell created_by: pr creation_date: 2012-12-12T10:21:07Z [Term] id: GO:1990182 name: exosomal secretion namespace: biological_process def: "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." [GOC:hjd, PMID:10572093, PMID:12154376, PMID:16773132, PMID:18617898] synonym: "exosomal protein secretion" NARROW [PMID:18617898] synonym: "exosomal secretory pathway" EXACT [PMID:18617898] synonym: "extracellular vesicular exosome secretion" EXACT [GOC:hjd] synonym: "multi-vesicular body fusion with plasma membrane" EXACT [] synonym: "secretion of exosome" EXACT [PMID:18617898] is_a: GO:0006887 ! exocytosis is_a: GO:0051650 ! establishment of vesicle localization intersection_of: GO:0006887 ! exocytosis intersection_of: has_primary_input GO:0070062 ! extracellular exosome relationship: has_primary_input GO:0070062 ! extracellular exosome relationship: part_of GO:0097734 ! extracellular exosome biogenesis property_value: RO:0002161 NCBITaxon:4890 created_by: hjd creation_date: 2013-09-04T21:08:14Z [Term] id: GO:1990234 name: transferase complex namespace: cellular_component def: "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)." [GOC:bhm, PMID:16540464] is_a: GO:1902494 ! catalytic complex intersection_of: GO:1902494 ! catalytic complex intersection_of: capable_of GO:0016740 ! transferase activity relationship: capable_of GO:0016740 ! transferase activity created_by: bhm creation_date: 2013-11-12T13:20:12Z [Term] id: GO:1990280 name: RNA localization to chromatin namespace: biological_process def: "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin." [GOC:dos, GOC:mah, PMID:22582262] synonym: "RNA localisation to chromatin" EXACT [] is_a: GO:0006403 ! RNA localization intersection_of: GO:0006403 ! RNA localization intersection_of: has_target_end_location GO:0000785 ! chromatin relationship: has_target_end_location GO:0000785 ! chromatin created_by: mah creation_date: 2014-01-30T15:55:34Z [Term] id: GO:1990351 name: transporter complex namespace: cellular_component def: "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells." [GOC:bhm, PMID:15449578] comment: An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay). is_a: GO:0032991 ! protein-containing complex intersection_of: GO:0032991 ! protein-containing complex intersection_of: capable_of GO:0005215 ! transporter activity relationship: capable_of GO:0005215 ! transporter activity created_by: bhm creation_date: 2014-03-26T14:23:27Z [Term] id: GO:1990375 name: baculum development namespace: biological_process def: "The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure." [GOC:sl, PMID:21471296] synonym: "os penis development" EXACT [GOC:sl] synonym: "penile bone development" EXACT [GOC:sl] synonym: "penis bone development" EXACT [GOC:sl] is_a: GO:0048608 ! reproductive structure development is_a: GO:0060348 ! bone development intersection_of: GO:0048856 ! anatomical structure development intersection_of: results_in_development_of UBERON:0006435 ! os penis relationship: results_in_development_of UBERON:0006435 ! os penis created_by: sl creation_date: 2014-05-01T23:59:13Z [Term] id: GO:1990705 name: cholangiocyte proliferation namespace: biological_process def: "The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water." [PMID:24434010] synonym: "hepatoblast proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:1000488 ! cholangiocyte relationship: acts_on_population_of CL:1000488 ! cholangiocyte creation_date: 2015-03-16T23:23:50Z [Term] id: GO:1990748 name: cellular detoxification namespace: biological_process def: "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." [GOC:vw] is_a: GO:0009987 ! cellular process is_a: GO:0098754 ! detoxification intersection_of: GO:0098754 ! detoxification intersection_of: occurs_in CL:0000000 ! cell relationship: occurs_in CL:0000000 ! cell relationship: part_of GO:0097237 ! cellular response to toxic substance created_by: vw creation_date: 2015-05-18T16:17:46Z [Term] id: GO:1990765 name: colon smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum." [PMID:24170253] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: occurs_in UBERON:0001155 ! colon relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in UBERON:0001155 ! colon relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014827 ! intestine smooth muscle contraction created_by: sl creation_date: 2015-06-10T18:29:21Z [Term] id: GO:1990768 name: gastric mucosal blood circulation namespace: biological_process def: "The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products." [PMID:10807413] synonym: "stomach mucosal blood circulation" EXACT [] is_a: GO:0008015 ! blood circulation intersection_of: GO:0008015 ! blood circulation intersection_of: occurs_in UBERON:0004786 ! gastrointestinal system mucosa relationship: occurs_in UBERON:0004786 ! gastrointestinal system mucosa created_by: sl creation_date: 2015-06-10T20:11:09Z [Term] id: GO:1990770 name: small intestine smooth muscle contraction namespace: biological_process def: "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine." [PMID:11991626] is_a: GO:0006939 ! smooth muscle contraction intersection_of: GO:0006939 ! smooth muscle contraction intersection_of: occurs_in UBERON:0002108 ! small intestine relationship: in_taxon NCBITaxon:7742 {all_only="true"} ! Vertebrata relationship: occurs_in UBERON:0002108 ! small intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of GO:0014827 ! intestine smooth muscle contraction created_by: sl creation_date: 2015-06-11T18:02:33Z [Term] id: GO:1990778 name: protein localization to cell periphery namespace: biological_process def: "A process in which a protein is transported to, or maintained in, the cell periphery." [PMID:18216290] is_a: GO:0008104 ! protein localization intersection_of: GO:0008104 ! protein localization intersection_of: has_target_end_location GO:0071944 ! cell periphery relationship: has_target_end_location GO:0071944 ! cell periphery creation_date: 2015-06-18T22:37:39Z [Term] id: GO:1990849 name: vacuolar localization namespace: biological_process def: "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell." [PMID:26283797] synonym: "maintenance of vacuolar localization" EXACT [] synonym: "maintenance of vacuolar location" NARROW [] synonym: "maintenance of vacuole localization" EXACT [] synonym: "maintenance of vacuole location" EXACT [] is_a: GO:0051640 ! organelle localization intersection_of: GO:0051179 ! localization intersection_of: has_primary_input GO:0005773 ! vacuole relationship: has_primary_input GO:0005773 ! vacuole property_value: IAO:0000233 "https://github.com/geneontology/go-ontology/issues/22182" xsd:anyURI created_by: mcc creation_date: 2015-09-10T08:16:02Z [Term] id: GO:1990863 name: acinar cell proliferation namespace: biological_process def: "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus)." [PMID:9788538] synonym: "acinic cell proliferation" EXACT [] synonym: "acinous cell proliferation" EXACT [] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000622 ! acinar cell relationship: acts_on_population_of CL:0000622 ! acinar cell created_by: sl creation_date: 2015-09-25T14:26:09Z [Term] id: GO:1990874 name: vascular associated smooth muscle cell proliferation namespace: biological_process def: "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." [PMID:23246467] synonym: "vascular smooth muscle cell proliferation" EXACT [] synonym: "VSMC proliferation" EXACT [] is_a: GO:0048659 ! smooth muscle cell proliferation intersection_of: GO:0008283 ! cell population proliferation intersection_of: acts_on_population_of CL:0000359 ! vascular associated smooth muscle cell relationship: acts_on_population_of CL:0000359 ! vascular associated smooth muscle cell created_by: sl creation_date: 2015-09-29T16:34:59Z [Term] id: GO:1990904 name: ribonucleoprotein complex namespace: cellular_component alt_id: GO:0030529 alt_id: GO:1990903 def: "A macromolecular complex that contains both RNA and protein molecules." [GOC:krc, GOC:vesicles] subset: goslim_pir synonym: "extracellular ribonucleoprotein complex" NARROW [] synonym: "intracellular ribonucleoprotein complex" NARROW [] synonym: "protein-RNA complex" EXACT [] synonym: "RNA-protein complex" EXACT [] synonym: "RNP" EXACT [] xref: Wikipedia:Ribonucleoprotein is_a: GO:0032991 ! protein-containing complex relationship: has_part CHEBI:33697 ! ribonucleic acid created_by: pr creation_date: 2015-11-19T12:26:37Z [Term] id: GO:1990917 name: ooplasm namespace: cellular_component def: "The cytoplasm of an ovum." [PMID:19022436] is_a: GO:0005737 ! cytoplasm intersection_of: GO:0005737 ! cytoplasm intersection_of: part_of CL:0000025 ! egg cell relationship: part_of CL:0000025 ! egg cell property_value: RO:0002161 NCBITaxon:4751 created_by: sl creation_date: 2015-12-10T21:40:16Z [Term] id: GO:2000018 name: regulation of male gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "regulation of testicular development" EXACT [GOC:obol] synonym: "regulation of testis development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008584 ! male gonad development relationship: regulates GO:0008584 ! male gonad development created_by: jl creation_date: 2010-07-15T03:29:05Z [Term] id: GO:2000019 name: negative regulation of male gonad development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." [GOC:obol, GOC:yaf] synonym: "negative regulation of testicular development" EXACT [GOC:obol] synonym: "negative regulation of testis development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008584 ! male gonad development relationship: negatively_regulates GO:0008584 ! male gonad development created_by: jl creation_date: 2010-07-15T03:29:10Z [Term] id: GO:2000020 name: positive regulation of male gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of male gonad development." [GOC:obol] synonym: "positive regulation of testicular development" EXACT [GOC:obol] synonym: "positive regulation of testis development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000018 ! regulation of male gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008584 ! male gonad development relationship: positively_regulates GO:0008584 ! male gonad development created_by: jl creation_date: 2010-07-15T03:29:13Z [Term] id: GO:2000026 name: regulation of multicellular organismal development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of multicellular organismal development." [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007275 ! multicellular organism development relationship: regulates GO:0007275 ! multicellular organism development created_by: tb creation_date: 2010-08-05T11:25:59Z [Term] id: GO:2000027 name: regulation of animal organ morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of animal organ morphogenesis." [GOC:obol] synonym: "regulation of histogenesis and organogenesis" RELATED [GOC:obol] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0009887 ! animal organ morphogenesis relationship: regulates GO:0009887 ! animal organ morphogenesis created_by: tb creation_date: 2010-08-05T11:26:27Z [Term] id: GO:2000035 name: regulation of stem cell division namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell division." [GOC:obol] synonym: "regulation of stem cell renewal" EXACT [GOC:obol] is_a: GO:0051302 ! regulation of cell division intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0017145 ! stem cell division relationship: regulates GO:0017145 ! stem cell division created_by: tb creation_date: 2010-08-05T11:34:53Z [Term] id: GO:2000036 name: regulation of stem cell population maintenance namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell population maintenance." [GOC:obol] synonym: "regulation of maintenance of pluripotency" RELATED [GOC:obol] is_a: GO:0050793 ! regulation of developmental process is_a: GO:0051239 ! regulation of multicellular organismal process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0019827 ! stem cell population maintenance relationship: regulates GO:0019827 ! stem cell population maintenance created_by: tb creation_date: 2010-08-05T11:35:25Z [Term] id: GO:2000061 name: regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0048634 ! regulation of muscle organ development is_a: GO:0051150 ! regulation of smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072193 ! ureter smooth muscle cell differentiation relationship: regulates GO:0072193 ! ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:16Z [Term] id: GO:2000062 name: negative regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051151 ! negative regulation of smooth muscle cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation relationship: negatively_regulates GO:0072193 ! ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:23Z [Term] id: GO:2000063 name: positive regulation of ureter smooth muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] is_a: GO:0051152 ! positive regulation of smooth muscle cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000061 ! regulation of ureter smooth muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation relationship: positively_regulates GO:0072193 ! ureter smooth muscle cell differentiation created_by: jl creation_date: 2010-08-20T01:44:28Z [Term] id: GO:2000068 name: regulation of defense response to insect namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defense response to insect." [GOC:obol] synonym: "regulation of physiological defense response to insect" EXACT [GOC:obol] is_a: GO:0031347 ! regulation of defense response intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002213 ! defense response to insect relationship: regulates GO:0002213 ! defense response to insect created_by: tb creation_date: 2010-08-23T09:30:00Z [Term] id: GO:2000074 name: regulation of type B pancreatic cell development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0060284 ! regulation of cell development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003323 ! type B pancreatic cell development relationship: regulates GO:0003323 ! type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:19:37Z [Term] id: GO:2000077 name: negative regulation of type B pancreatic cell development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "negative regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "negative regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010721 ! negative regulation of cell development is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003323 ! type B pancreatic cell development relationship: negatively_regulates GO:0003323 ! type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:21:17Z [Term] id: GO:2000078 name: positive regulation of type B pancreatic cell development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development." [GOC:obol, GOC:yaf] synonym: "positive regulation of pancreatic B cell development" EXACT [GOC:mah] synonym: "positive regulation of pancreatic beta cell development" EXACT [GOC:obol] is_a: GO:0010720 ! positive regulation of cell development is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000074 ! regulation of type B pancreatic cell development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003323 ! type B pancreatic cell development relationship: positively_regulates GO:0003323 ! type B pancreatic cell development created_by: tb creation_date: 2010-08-27T11:21:19Z [Term] id: GO:2000084 name: regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:06:41Z [Term] id: GO:2000085 name: negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "negative regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000697 ! negative regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: negatively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:08:21Z [Term] id: GO:2000086 name: positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis." [GOC:mtg_kidney_jan10] synonym: "positive regulation of mesonephric mesenchyme to epithelial transition" RELATED [GOC:obol] is_a: GO:2000084 ! regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis relationship: positively_regulates GO:0061261 ! mesenchymal to epithelial transition involved in mesonephros morphogenesis created_by: dph creation_date: 2010-09-03T06:08:24Z [Term] id: GO:2000106 name: regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "regulation of leukocyte apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071887 ! leukocyte apoptotic process relationship: regulates GO:0071887 ! leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:05Z [Term] id: GO:2000107 name: negative regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "negative regulation of leukocyte apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071887 ! leukocyte apoptotic process relationship: negatively_regulates GO:0071887 ! leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:09Z [Term] id: GO:2000108 name: positive regulation of leukocyte apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process." [GOC:BHF, GOC:mtg_apoptosis] synonym: "positive regulation of leukocyte apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071887 ! leukocyte apoptotic process relationship: positively_regulates GO:0071887 ! leukocyte apoptotic process created_by: mah creation_date: 2010-09-15T01:42:12Z [Term] id: GO:2000114 name: regulation of establishment of cell polarity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of establishment of cell polarity." [GOC:dph] synonym: "regulation of bud site selection/establishment of cell polarity" RELATED [GOC:obol] synonym: "regulation of cell polarization" EXACT [GOC:obol] is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030010 ! establishment of cell polarity relationship: regulates GO:0030010 ! establishment of cell polarity created_by: dph creation_date: 2010-09-16T01:22:36Z [Term] id: GO:2000136 name: regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis relationship: regulates GO:0061323 ! cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:53Z [Term] id: GO:2000137 name: negative regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis relationship: negatively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:55Z [Term] id: GO:2000138 name: positive regulation of cell proliferation involved in heart morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000136 ! regulation of cell proliferation involved in heart morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis relationship: positively_regulates GO:0061323 ! cell proliferation involved in heart morphogenesis created_by: dph creation_date: 2010-09-29T12:43:57Z [Term] id: GO:2000145 name: regulation of cell motility namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell motility." [GOC:mah] synonym: "regulation of cell locomotion" EXACT [GOC:obol] synonym: "regulation of cell movement" RELATED [GOC:obol] synonym: "regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040012 ! regulation of locomotion is_a: GO:0050794 ! regulation of cellular process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048870 ! cell motility relationship: regulates GO:0048870 ! cell motility created_by: mah creation_date: 2010-10-01T09:41:21Z [Term] id: GO:2000146 name: negative regulation of cell motility namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." [GOC:mah] synonym: "negative regulation of cell locomotion" EXACT [GOC:obol] synonym: "negative regulation of cell movement" RELATED [GOC:obol] synonym: "negative regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040013 ! negative regulation of locomotion is_a: GO:0048523 ! negative regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048870 ! cell motility relationship: negatively_regulates GO:0048870 ! cell motility created_by: mah creation_date: 2010-10-01T09:41:26Z [Term] id: GO:2000147 name: positive regulation of cell motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell motility." [GOC:mah] synonym: "positive regulation of cell locomotion" EXACT [GOC:obol] synonym: "positive regulation of cell movement" RELATED [GOC:obol] synonym: "positive regulation of movement of a cell" EXACT [GOC:obol] is_a: GO:0040017 ! positive regulation of locomotion is_a: GO:0048522 ! positive regulation of cellular process is_a: GO:2000145 ! regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048870 ! cell motility relationship: positively_regulates GO:0048870 ! cell motility created_by: mah creation_date: 2010-10-01T09:41:30Z [Term] id: GO:2000155 name: positive regulation of cilium-dependent cell motility namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility." [GOC:cilia, GOC:jl] synonym: "positive regulation of ciliary cell motility" RELATED [] is_a: GO:1902019 ! regulation of cilium-dependent cell motility is_a: GO:2000147 ! positive regulation of cell motility intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060285 ! cilium-dependent cell motility relationship: positively_regulates GO:0060285 ! cilium-dependent cell motility created_by: mah creation_date: 2010-10-04T12:41:05Z [Term] id: GO:2000172 name: regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0060688 ! regulation of morphogenesis of a branching structure intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048755 ! branching morphogenesis of a nerve relationship: regulates GO:0048755 ! branching morphogenesis of a nerve created_by: rl creation_date: 2010-10-07T12:07:54Z [Term] id: GO:2000173 name: negative regulation of branching morphogenesis of a nerve namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000172 ! regulation of branching morphogenesis of a nerve intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve relationship: negatively_regulates GO:0048755 ! branching morphogenesis of a nerve created_by: rl creation_date: 2010-10-07T12:07:56Z [Term] id: GO:2000174 name: regulation of pro-T cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045580 ! regulation of T cell differentiation is_a: GO:1905456 ! regulation of lymphoid progenitor cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002572 ! pro-T cell differentiation relationship: regulates GO:0002572 ! pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:30Z [Term] id: GO:2000175 name: negative regulation of pro-T cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "negative regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045581 ! negative regulation of T cell differentiation is_a: GO:1905457 ! negative regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002572 ! pro-T cell differentiation relationship: negatively_regulates GO:0002572 ! pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:33Z [Term] id: GO:2000176 name: positive regulation of pro-T cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation." [GOC:BHF] synonym: "positive regulation of pro-T lymphocyte differentiation" EXACT [GOC:obol] is_a: GO:0045582 ! positive regulation of T cell differentiation is_a: GO:1905458 ! positive regulation of lymphoid progenitor cell differentiation is_a: GO:2000174 ! regulation of pro-T cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002572 ! pro-T cell differentiation relationship: positively_regulates GO:0002572 ! pro-T cell differentiation created_by: mah creation_date: 2010-10-11T10:24:35Z [Term] id: GO:2000177 name: regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061351 ! neural precursor cell proliferation relationship: regulates GO:0061351 ! neural precursor cell proliferation created_by: dph creation_date: 2010-10-13T12:40:41Z [Term] id: GO:2000178 name: negative regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061351 ! neural precursor cell proliferation relationship: negatively_regulates GO:0061351 ! neural precursor cell proliferation created_by: dph creation_date: 2010-10-13T12:40:43Z [Term] id: GO:2000179 name: positive regulation of neural precursor cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation." [GOC:dph, GOC:yaf] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000177 ! regulation of neural precursor cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061351 ! neural precursor cell proliferation relationship: positively_regulates GO:0061351 ! neural precursor cell proliferation created_by: dph creation_date: 2010-10-13T12:40:45Z [Term] id: GO:2000181 name: negative regulation of blood vessel morphogenesis namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis." [GOC:dph, GOC:yaf] is_a: GO:0022603 ! regulation of anatomical structure morphogenesis is_a: GO:1901343 ! negative regulation of vasculature development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048514 ! blood vessel morphogenesis relationship: negatively_regulates GO:0048514 ! blood vessel morphogenesis created_by: dph creation_date: 2010-10-13T12:46:31Z [Term] id: GO:2000185 name: regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "regulation of phosphate membrane transport" EXACT [] is_a: GO:0010966 ! regulation of phosphate transport is_a: GO:1903795 ! regulation of inorganic anion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035435 ! phosphate ion transmembrane transport relationship: regulates GO:0035435 ! phosphate ion transmembrane transport created_by: vw creation_date: 2010-10-15T11:33:04Z [Term] id: GO:2000186 name: negative regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "negative regulation of phosphate membrane transport" EXACT [] is_a: GO:1903796 ! negative regulation of inorganic anion transmembrane transport is_a: GO:2000185 ! regulation of phosphate transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport relationship: negatively_regulates GO:0035435 ! phosphate ion transmembrane transport created_by: vw creation_date: 2010-10-15T11:33:08Z [Term] id: GO:2000187 name: positive regulation of phosphate transmembrane transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport." [GOC:obol] synonym: "positive regulation of phosphate membrane transport" EXACT [] is_a: GO:1903797 ! positive regulation of inorganic anion transmembrane transport is_a: GO:2000185 ! regulation of phosphate transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035435 ! phosphate ion transmembrane transport relationship: positively_regulates GO:0035435 ! phosphate ion transmembrane transport created_by: vw creation_date: 2010-10-15T11:33:10Z [Term] id: GO:2000194 name: regulation of female gonad development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "regulation of ovarian development" EXACT [GOC:obol] synonym: "regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905939 ! regulation of gonad development is_a: GO:2000026 ! regulation of multicellular organismal development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008585 ! female gonad development relationship: regulates GO:0008585 ! female gonad development created_by: yaf creation_date: 2010-10-19T10:45:34Z [Term] id: GO:2000195 name: negative regulation of female gonad development namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "negative regulation of ovarian development" EXACT [GOC:obol] synonym: "negative regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905940 ! negative regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008585 ! female gonad development relationship: negatively_regulates GO:0008585 ! female gonad development created_by: yaf creation_date: 2010-10-19T10:45:38Z [Term] id: GO:2000196 name: positive regulation of female gonad development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of female gonad development." [GOC:obol] synonym: "positive regulation of ovarian development" EXACT [GOC:obol] synonym: "positive regulation of ovary development" EXACT [GOC:obol] is_a: GO:1905941 ! positive regulation of gonad development is_a: GO:2000194 ! regulation of female gonad development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008585 ! female gonad development relationship: positively_regulates GO:0008585 ! female gonad development created_by: yaf creation_date: 2010-10-19T10:45:41Z [Term] id: GO:2000226 name: regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003310 ! pancreatic A cell differentiation relationship: regulates GO:0003310 ! pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:37Z [Term] id: GO:2000227 name: negative regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "negative regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0003310 ! pancreatic A cell differentiation relationship: negatively_regulates GO:0003310 ! pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:40Z [Term] id: GO:2000228 name: positive regulation of pancreatic A cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation." [GOC:mah] synonym: "positive regulation of pancreatic alpha cell differentiation" EXACT [GOC:obol] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000226 ! regulation of pancreatic A cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0003310 ! pancreatic A cell differentiation relationship: positively_regulates GO:0003310 ! pancreatic A cell differentiation created_by: mah creation_date: 2010-11-09T03:43:42Z [Term] id: GO:2000241 name: regulation of reproductive process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0050789 ! regulation of biological process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0022414 ! reproductive process relationship: regulates GO:0022414 ! reproductive process created_by: mah creation_date: 2010-11-10T02:44:02Z [Term] id: GO:2000242 name: negative regulation of reproductive process namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048519 ! negative regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0022414 ! reproductive process relationship: negatively_regulates GO:0022414 ! reproductive process created_by: mah creation_date: 2010-11-10T02:44:05Z [Term] id: GO:2000243 name: positive regulation of reproductive process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of reproductive process." [GOC:mah] is_a: GO:0048518 ! positive regulation of biological process is_a: GO:2000241 ! regulation of reproductive process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0022414 ! reproductive process relationship: positively_regulates GO:0022414 ! reproductive process created_by: mah creation_date: 2010-11-10T02:44:08Z [Term] id: GO:2000248 name: negative regulation of establishment or maintenance of neuroblast polarity namespace: biological_process def: "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity." [GOC:obol] synonym: "negative regulation of establishment and/or maintenance of neuroblast cell polarity" EXACT [GOC:obol] is_a: GO:0010454 ! negative regulation of cell fate commitment is_a: GO:0032878 ! regulation of establishment or maintenance of cell polarity is_a: GO:0045769 ! negative regulation of asymmetric cell division intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity relationship: negatively_regulates GO:0045196 ! establishment or maintenance of neuroblast polarity created_by: vw creation_date: 2010-11-11T11:40:34Z [Term] id: GO:2000254 name: regulation of male germ cell proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905936 ! regulation of germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0002176 ! male germ cell proliferation relationship: regulates GO:0002176 ! male germ cell proliferation created_by: dph creation_date: 2010-11-18T09:29:44Z [Term] id: GO:2000255 name: negative regulation of male germ cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905937 ! negative regulation of germ cell proliferation is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0002176 ! male germ cell proliferation relationship: negatively_regulates GO:0002176 ! male germ cell proliferation created_by: dph creation_date: 2010-11-18T09:29:47Z [Term] id: GO:2000256 name: positive regulation of male germ cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation." [GOC:obol] is_a: GO:1905938 ! positive regulation of germ cell proliferation is_a: GO:2000254 ! regulation of male germ cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0002176 ! male germ cell proliferation relationship: positively_regulates GO:0002176 ! male germ cell proliferation created_by: dph creation_date: 2010-11-18T09:29:50Z [Term] id: GO:2000269 name: regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "regulation of fibroblast apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0044346 ! fibroblast apoptotic process relationship: regulates GO:0044346 ! fibroblast apoptotic process created_by: jl creation_date: 2010-11-23T01:07:23Z [Term] id: GO:2000270 name: negative regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "negative regulation of fibroblast apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0044346 ! fibroblast apoptotic process relationship: negatively_regulates GO:0044346 ! fibroblast apoptotic process created_by: jl creation_date: 2010-11-23T01:07:27Z [Term] id: GO:2000271 name: positive regulation of fibroblast apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process." [GOC:mtg_apoptosis, GOC:obol, GOC:yaf] synonym: "positive regulation of fibroblast apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2000269 ! regulation of fibroblast apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0044346 ! fibroblast apoptotic process relationship: positively_regulates GO:0044346 ! fibroblast apoptotic process created_by: jl creation_date: 2010-11-23T01:07:29Z [Term] id: GO:2000278 name: regulation of DNA biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "regulation of DNA anabolism" EXACT [GOC:obol] synonym: "regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of DNA formation" EXACT [GOC:obol] synonym: "regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0051052 ! regulation of DNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0071897 ! DNA biosynthetic process relationship: regulates GO:0071897 ! DNA biosynthetic process created_by: yaf creation_date: 2010-12-08T04:48:15Z [Term] id: GO:2000279 name: negative regulation of DNA biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "negative regulation of DNA anabolism" EXACT [GOC:obol] synonym: "negative regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of DNA formation" EXACT [GOC:obol] synonym: "negative regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010558 ! negative regulation of macromolecule biosynthetic process is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0051053 ! negative regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0071897 ! DNA biosynthetic process relationship: negatively_regulates GO:0071897 ! DNA biosynthetic process created_by: yaf creation_date: 2010-12-08T04:48:20Z [Term] id: GO:2000282 name: regulation of cellular amino acid biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "regulation of amino acid biosynthetic process" EXACT [GOC:obol] synonym: "regulation of cellular amino acid anabolism" EXACT [GOC:obol] synonym: "regulation of cellular amino acid biosynthesis" EXACT [GOC:obol] synonym: "regulation of cellular amino acid formation" EXACT [GOC:obol] synonym: "regulation of cellular amino acid synthesis" EXACT [GOC:obol] is_a: GO:0006521 ! regulation of cellular amino acid metabolic process is_a: GO:0031326 ! regulation of cellular biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008652 ! amino acid biosynthetic process relationship: regulates GO:0008652 ! amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:19Z [Term] id: GO:2000283 name: negative regulation of amino acid biosynthetic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process." [GOC:obol] synonym: "negative regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "negative regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "negative regulation of amino acid formation" EXACT [GOC:obol] synonym: "negative regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "negative regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0031327 ! negative regulation of cellular biosynthetic process is_a: GO:0045763 ! negative regulation of cellular amino acid metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008652 ! amino acid biosynthetic process relationship: negatively_regulates GO:0008652 ! amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:23Z [Term] id: GO:2000284 name: positive regulation of amino acid biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process." [GOC:obol] synonym: "positive regulation of amino acid anabolism" EXACT [GOC:obol] synonym: "positive regulation of amino acid biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of amino acid formation" EXACT [GOC:obol] synonym: "positive regulation of amino acid synthesis" EXACT [GOC:obol] synonym: "positive regulation of cellular amino acid biosynthetic process" EXACT [GOC:obol] is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0045764 ! positive regulation of amino acid metabolic process is_a: GO:2000282 ! regulation of cellular amino acid biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008652 ! amino acid biosynthetic process relationship: positively_regulates GO:0008652 ! amino acid biosynthetic process created_by: vw creation_date: 2010-12-10T11:54:27Z [Term] id: GO:2000287 name: positive regulation of myotome development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myotome development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000290 ! regulation of myotome development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061055 ! myotome development relationship: positively_regulates GO:0061055 ! myotome development created_by: rl creation_date: 2010-12-16T05:17:15Z [Term] id: GO:2000288 name: positive regulation of myoblast proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of myoblast proliferation." [GOC:BHF] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051450 ! myoblast proliferation relationship: positively_regulates GO:0051450 ! myoblast proliferation created_by: rl creation_date: 2010-12-16T05:20:52Z [Term] id: GO:2000290 name: regulation of myotome development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myotome development." [GOC:mah] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061055 ! myotome development relationship: regulates GO:0061055 ! myotome development created_by: mah creation_date: 2010-12-20T10:22:05Z [Term] id: GO:2000291 name: regulation of myoblast proliferation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of myoblast proliferation." [GOC:mah] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0051450 ! myoblast proliferation relationship: regulates GO:0051450 ! myoblast proliferation created_by: mah creation_date: 2010-12-20T10:34:26Z [Term] id: GO:2000292 name: regulation of defecation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0044058 ! regulation of digestive system process is_a: GO:0044062 ! regulation of excretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0030421 ! defecation relationship: regulates GO:0030421 ! defecation created_by: bf creation_date: 2010-12-21T09:23:08Z [Term] id: GO:2000293 name: negative regulation of defecation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051048 ! negative regulation of secretion is_a: GO:0060457 ! negative regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0030421 ! defecation relationship: negatively_regulates GO:0030421 ! defecation created_by: bf creation_date: 2010-12-21T09:23:13Z [Term] id: GO:2000294 name: positive regulation of defecation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of defecation." [GOC:obol] is_a: GO:0051047 ! positive regulation of secretion is_a: GO:0060456 ! positive regulation of digestive system process is_a: GO:2000292 ! regulation of defecation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0030421 ! defecation relationship: positively_regulates GO:0030421 ! defecation created_by: bf creation_date: 2010-12-21T09:23:16Z [Term] id: GO:2000351 name: regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process." [GOC:mah, GOC:mtg_apoptosis] synonym: "regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "regulation of endothelial cell apoptosis" NARROW [] synonym: "regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072577 ! endothelial cell apoptotic process relationship: regulates GO:0072577 ! endothelial cell apoptotic process created_by: mah creation_date: 2011-02-03T10:43:16Z [Term] id: GO:2000352 name: negative regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "negative regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of endothelial cell apoptosis" NARROW [] synonym: "negative regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "negative regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072577 ! endothelial cell apoptotic process relationship: negatively_regulates GO:0072577 ! endothelial cell apoptotic process created_by: mah creation_date: 2011-02-03T10:43:20Z [Term] id: GO:2000353 name: positive regulation of endothelial cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process." [GOC:BHF, GOC:mah, GOC:mtg_apoptosis] synonym: "positive regulation of apoptosis of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of endothelial cell apoptosis" NARROW [] synonym: "positive regulation of endothelial cell programmed cell death by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of killing of endothelial cells" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death of endothelial cells by apoptosis" EXACT [GOC:obol] synonym: "positive regulation of programmed cell death, endothelial cells" EXACT [GOC:obol] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:2000351 ! regulation of endothelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072577 ! endothelial cell apoptotic process relationship: positively_regulates GO:0072577 ! endothelial cell apoptotic process created_by: mah creation_date: 2011-02-03T10:43:23Z [Term] id: GO:2000374 name: regulation of oxygen metabolic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031323 ! regulation of cellular metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072592 ! oxygen metabolic process relationship: regulates GO:0072592 ! oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:32Z [Term] id: GO:2000375 name: negative regulation of oxygen metabolic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "negative regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "negative regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031324 ! negative regulation of cellular metabolic process is_a: GO:2000374 ! regulation of oxygen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072592 ! oxygen metabolic process relationship: negatively_regulates GO:0072592 ! oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:44Z [Term] id: GO:2000376 name: positive regulation of oxygen metabolic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process." [GOC:mah] synonym: "positive regulation of diatomic oxygen metabolic process" EXACT [GOC:obol] synonym: "positive regulation of oxygen metabolism" EXACT [GOC:obol] is_a: GO:0031325 ! positive regulation of cellular metabolic process is_a: GO:2000374 ! regulation of oxygen metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072592 ! oxygen metabolic process relationship: positively_regulates GO:0072592 ! oxygen metabolic process created_by: mah creation_date: 2011-02-11T02:03:52Z [Term] id: GO:2000380 name: regulation of mesoderm development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007498 ! mesoderm development relationship: regulates GO:0007498 ! mesoderm development created_by: vk creation_date: 2011-02-15T03:09:46Z [Term] id: GO:2000381 name: negative regulation of mesoderm development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007498 ! mesoderm development relationship: negatively_regulates GO:0007498 ! mesoderm development created_by: vk creation_date: 2011-02-15T03:10:02Z [Term] id: GO:2000382 name: positive regulation of mesoderm development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000380 ! regulation of mesoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007498 ! mesoderm development relationship: positively_regulates GO:0007498 ! mesoderm development created_by: vk creation_date: 2011-02-15T03:10:12Z [Term] id: GO:2000383 name: regulation of ectoderm development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0050793 ! regulation of developmental process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0007398 ! ectoderm development relationship: regulates GO:0007398 ! ectoderm development created_by: vk creation_date: 2011-02-15T03:17:10Z [Term] id: GO:2000384 name: negative regulation of ectoderm development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007398 ! ectoderm development relationship: negatively_regulates GO:0007398 ! ectoderm development created_by: vk creation_date: 2011-02-15T03:17:27Z [Term] id: GO:2000385 name: positive regulation of ectoderm development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of ectoderm development." [GOC:BHF] is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:2000383 ! regulation of ectoderm development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007398 ! ectoderm development relationship: positively_regulates GO:0007398 ! ectoderm development created_by: vk creation_date: 2011-02-15T03:17:39Z [Term] id: GO:2000401 name: regulation of lymphocyte migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071675 ! regulation of mononuclear cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072676 ! lymphocyte migration relationship: regulates GO:0072676 ! lymphocyte migration created_by: mah creation_date: 2011-02-23T10:45:19Z [Term] id: GO:2000402 name: negative regulation of lymphocyte migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071676 ! negative regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072676 ! lymphocyte migration relationship: negatively_regulates GO:0072676 ! lymphocyte migration created_by: mah creation_date: 2011-02-23T10:45:47Z [Term] id: GO:2000403 name: positive regulation of lymphocyte migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of lymphocyte migration." [GOC:mah] is_a: GO:0071677 ! positive regulation of mononuclear cell migration is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072676 ! lymphocyte migration relationship: positively_regulates GO:0072676 ! lymphocyte migration created_by: mah creation_date: 2011-02-23T10:46:06Z [Term] id: GO:2000404 name: regulation of T cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "regulation of T-cell migration" EXACT [GOC:obol] synonym: "regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000401 ! regulation of lymphocyte migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0072678 ! T cell migration relationship: regulates GO:0072678 ! T cell migration created_by: mah creation_date: 2011-02-23T10:48:24Z [Term] id: GO:2000405 name: negative regulation of T cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "negative regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "negative regulation of T-cell migration" EXACT [GOC:obol] synonym: "negative regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000402 ! negative regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072678 ! T cell migration relationship: negatively_regulates GO:0072678 ! T cell migration created_by: mah creation_date: 2011-02-23T10:48:52Z [Term] id: GO:2000406 name: positive regulation of T cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of T cell migration." [GOC:mah] synonym: "positive regulation of T lymphocyte migration" EXACT [GOC:obol] synonym: "positive regulation of T-cell migration" EXACT [GOC:obol] synonym: "positive regulation of T-lymphocyte migration" EXACT [GOC:obol] is_a: GO:2000403 ! positive regulation of lymphocyte migration is_a: GO:2000404 ! regulation of T cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072678 ! T cell migration relationship: positively_regulates GO:0072678 ! T cell migration created_by: mah creation_date: 2011-02-23T10:49:12Z [Term] id: GO:2000471 name: regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035701 ! hematopoietic stem cell migration relationship: regulates GO:0035701 ! hematopoietic stem cell migration created_by: bf creation_date: 2011-03-09T09:34:08Z [Term] id: GO:2000472 name: negative regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "negative regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035701 ! hematopoietic stem cell migration relationship: negatively_regulates GO:0035701 ! hematopoietic stem cell migration created_by: bf creation_date: 2011-03-09T09:34:54Z [Term] id: GO:2000473 name: positive regulation of hematopoietic stem cell migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration." [GOC:obol] synonym: "positive regulation of hemopoietic stem cell migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2000471 ! regulation of hematopoietic stem cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035701 ! hematopoietic stem cell migration relationship: positively_regulates GO:0035701 ! hematopoietic stem cell migration created_by: bf creation_date: 2011-03-09T09:35:25Z [Term] id: GO:2000495 name: regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0042127 ! regulation of cell population proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis relationship: regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:18:34Z [Term] id: GO:2000496 name: negative regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis relationship: negatively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:19:22Z [Term] id: GO:2000497 name: positive regulation of cell proliferation involved in compound eye morphogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis." [GOC:obol] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:2000495 ! regulation of cell proliferation involved in compound eye morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis relationship: positively_regulates GO:0035736 ! cell proliferation involved in compound eye morphogenesis created_by: bf creation_date: 2011-03-18T02:19:54Z [Term] id: GO:2000542 name: negative regulation of gastrulation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0045992 ! negative regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0007369 ! gastrulation relationship: negatively_regulates GO:0007369 ! gastrulation created_by: yaf creation_date: 2011-04-01T04:10:08Z [Term] id: GO:2000543 name: positive regulation of gastrulation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of gastrulation." [GOC:obol] is_a: GO:0010470 ! regulation of gastrulation is_a: GO:0040019 ! positive regulation of embryonic development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0007369 ! gastrulation relationship: positively_regulates GO:0007369 ! gastrulation created_by: yaf creation_date: 2011-04-01T04:10:15Z [Term] id: GO:2000547 name: regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120032 ! regulation of plasma membrane bounded cell projection assembly intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097026 ! dendritic cell dendrite assembly relationship: regulates GO:0097026 ! dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:21:55Z [Term] id: GO:2000548 name: negative regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "negative regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120033 ! negative regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly relationship: negatively_regulates GO:0097026 ! dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:22:01Z [Term] id: GO:2000549 name: positive regulation of dendritic cell dendrite assembly namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly." [GOC:obol] synonym: "positive regulation of dendritic extension" RELATED [GOC:obol] is_a: GO:0120034 ! positive regulation of plasma membrane bounded cell projection assembly is_a: GO:2000547 ! regulation of dendritic cell dendrite assembly intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097026 ! dendritic cell dendrite assembly relationship: positively_regulates GO:0097026 ! dendritic cell dendrite assembly created_by: ebc creation_date: 2011-04-03T07:22:06Z [Term] id: GO:2000573 name: positive regulation of DNA biosynthetic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." [GOC:obol] synonym: "positive regulation of DNA anabolism" EXACT [GOC:obol] synonym: "positive regulation of DNA biosynthesis" EXACT [GOC:obol] synonym: "positive regulation of DNA formation" EXACT [GOC:obol] synonym: "positive regulation of DNA synthesis" EXACT [GOC:obol] is_a: GO:0010557 ! positive regulation of macromolecule biosynthetic process is_a: GO:0031328 ! positive regulation of cellular biosynthetic process is_a: GO:0051054 ! positive regulation of DNA metabolic process is_a: GO:2000278 ! regulation of DNA biosynthetic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0071897 ! DNA biosynthetic process relationship: positively_regulates GO:0071897 ! DNA biosynthetic process created_by: yaf creation_date: 2011-04-04T10:01:20Z [Term] id: GO:2000606 name: regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901722 ! regulation of cell proliferation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0061209 ! cell proliferation involved in mesonephros development relationship: regulates GO:0061209 ! cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:19Z [Term] id: GO:2000607 name: negative regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901723 ! negative regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development relationship: negatively_regulates GO:0061209 ! cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:23Z [Term] id: GO:2000608 name: positive regulation of cell proliferation involved in mesonephros development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development." [GOC:obol] is_a: GO:1901724 ! positive regulation of cell proliferation involved in kidney development is_a: GO:2000606 ! regulation of cell proliferation involved in mesonephros development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development relationship: positively_regulates GO:0061209 ! cell proliferation involved in mesonephros development created_by: yaf creation_date: 2011-04-18T08:42:25Z [Term] id: GO:2000647 name: negative regulation of stem cell proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0072089 ! stem cell proliferation relationship: negatively_regulates GO:0072089 ! stem cell proliferation created_by: dph creation_date: 2011-04-27T01:04:22Z [Term] id: GO:2000648 name: positive regulation of stem cell proliferation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell proliferation." [GOC:dph] is_a: GO:0008284 ! positive regulation of cell population proliferation is_a: GO:0072091 ! regulation of stem cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072089 ! stem cell proliferation relationship: positively_regulates GO:0072089 ! stem cell proliferation created_by: dph creation_date: 2011-04-27T01:04:25Z [Term] id: GO:2000649 name: regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: term_scheduled_for_obsoletion synonym: "regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032412 ! regulation of monoatomic ion transmembrane transporter activity is_a: GO:1902305 ! regulation of sodium ion transmembrane transport intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0015081 ! sodium ion transmembrane transporter activity relationship: regulates GO:0015081 ! sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:42:53Z [Term] id: GO:2000650 name: negative regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: term_scheduled_for_obsoletion synonym: "negative regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032413 ! negative regulation of ion transmembrane transporter activity is_a: GO:1902306 ! negative regulation of sodium ion transmembrane transport is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity relationship: negatively_regulates GO:0015081 ! sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:42:57Z [Term] id: GO:2000651 name: positive regulation of sodium ion transmembrane transporter activity namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity." [GOC:obol] subset: term_scheduled_for_obsoletion synonym: "positive regulation of sodium transporter activity" EXACT [GOC:obol] is_a: GO:0032414 ! positive regulation of ion transmembrane transporter activity is_a: GO:1902307 ! positive regulation of sodium ion transmembrane transport is_a: GO:2000649 ! regulation of sodium ion transmembrane transporter activity intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity relationship: positively_regulates GO:0015081 ! sodium ion transmembrane transporter activity created_by: yaf creation_date: 2011-04-28T08:43:00Z [Term] id: GO:2000668 name: regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000106 ! regulation of leukocyte apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097048 ! dendritic cell apoptotic process relationship: regulates GO:0097048 ! dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:16Z [Term] id: GO:2000669 name: negative regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000107 ! negative regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097048 ! dendritic cell apoptotic process relationship: negatively_regulates GO:0097048 ! dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:21Z [Term] id: GO:2000670 name: positive regulation of dendritic cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of dendritic cell apoptosis" NARROW [] is_a: GO:2000108 ! positive regulation of leukocyte apoptotic process is_a: GO:2000668 ! regulation of dendritic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097048 ! dendritic cell apoptotic process relationship: positively_regulates GO:0097048 ! dendritic cell apoptotic process created_by: pr creation_date: 2011-05-09T07:34:26Z [Term] id: GO:2000671 name: regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043523 ! regulation of neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097049 ! motor neuron apoptotic process relationship: regulates GO:0097049 ! motor neuron apoptotic process created_by: pr creation_date: 2011-05-09T10:56:17Z [Term] id: GO:2000672 name: negative regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "negative regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043524 ! negative regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097049 ! motor neuron apoptotic process relationship: negatively_regulates GO:0097049 ! motor neuron apoptotic process created_by: pr creation_date: 2011-05-09T10:56:21Z [Term] id: GO:2000673 name: positive regulation of motor neuron apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of motoneuron apoptosis" EXACT [GOC:obol] synonym: "positive regulation of motor neuron apoptosis" NARROW [] is_a: GO:0043525 ! positive regulation of neuron apoptotic process is_a: GO:2000671 ! regulation of motor neuron apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097049 ! motor neuron apoptotic process relationship: positively_regulates GO:0097049 ! motor neuron apoptotic process created_by: pr creation_date: 2011-05-09T10:56:24Z [Term] id: GO:2000674 name: regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904035 ! regulation of epithelial cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097050 ! type B pancreatic cell apoptotic process relationship: regulates GO:0097050 ! type B pancreatic cell apoptotic process created_by: pr creation_date: 2011-05-09T11:51:09Z [Term] id: GO:2000675 name: negative regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "negative regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "negative regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904036 ! negative regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process relationship: negatively_regulates GO:0097050 ! type B pancreatic cell apoptotic process created_by: pr creation_date: 2011-05-09T11:51:12Z [Term] id: GO:2000676 name: positive regulation of type B pancreatic cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of pancreatic B cell apoptosis" EXACT [GOC:obol] synonym: "positive regulation of pancreatic beta cell apoptosis" EXACT [GOC:obol] synonym: "positive regulation of type B pancreatic cell apoptosis" NARROW [] is_a: GO:1904037 ! positive regulation of epithelial cell apoptotic process is_a: GO:2000674 ! regulation of type B pancreatic cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process relationship: positively_regulates GO:0097050 ! type B pancreatic cell apoptotic process created_by: pr creation_date: 2011-05-09T11:51:15Z [Term] id: GO:2000690 name: regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045661 ! regulation of myoblast differentiation is_a: GO:0051890 ! regulation of cardioblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation relationship: regulates GO:0060379 ! cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:01Z [Term] id: GO:2000691 name: negative regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "negative regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "negative regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045662 ! negative regulation of myoblast differentiation is_a: GO:0051892 ! negative regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation relationship: negatively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:06Z [Term] id: GO:2000696 name: regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030856 ! regulation of epithelial cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development relationship: regulates GO:0035850 ! epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:52Z [Term] id: GO:2000697 name: negative regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030857 ! negative regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development relationship: negatively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:55Z [Term] id: GO:2000698 name: positive regulation of epithelial cell differentiation involved in kidney development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development." [GOC:mtg_kidney_jan10, GOC:yaf] is_a: GO:0030858 ! positive regulation of epithelial cell differentiation is_a: GO:2000696 ! regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development relationship: positively_regulates GO:0035850 ! epithelial cell differentiation involved in kidney development created_by: bf creation_date: 2011-05-16T04:23:57Z [Term] id: GO:2000700 name: positive regulation of cardiac muscle cell myoblast differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation." [GOC:obol] synonym: "positive regulation of cardiac myoblast differentiation" RELATED [GOC:obol] synonym: "positive regulation of myocardial precursor cell differentiation" EXACT [GOC:obol] is_a: GO:0045663 ! positive regulation of myoblast differentiation is_a: GO:0051891 ! positive regulation of cardioblast differentiation is_a: GO:2000690 ! regulation of cardiac muscle cell myoblast differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation relationship: positively_regulates GO:0060379 ! cardiac muscle cell myoblast differentiation created_by: yaf creation_date: 2011-05-25T09:08:09Z [Term] id: GO:2000725 name: regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051153 ! regulation of striated muscle cell differentiation is_a: GO:1905207 ! regulation of cardiocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0055007 ! cardiac muscle cell differentiation relationship: regulates GO:0055007 ! cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:06Z [Term] id: GO:2000726 name: negative regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "negative regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "negative regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051154 ! negative regulation of striated muscle cell differentiation is_a: GO:1905208 ! negative regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation relationship: negatively_regulates GO:0055007 ! cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:11Z [Term] id: GO:2000727 name: positive regulation of cardiac muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation." [GOC:BHF] synonym: "positive regulation of cardiomyocyte differentiation" EXACT [GOC:obol] synonym: "positive regulation of heart muscle cell differentiation" RELATED [GOC:obol] is_a: GO:0051155 ! positive regulation of striated muscle cell differentiation is_a: GO:1905209 ! positive regulation of cardiocyte differentiation is_a: GO:2000725 ! regulation of cardiac muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0055007 ! cardiac muscle cell differentiation relationship: positively_regulates GO:0055007 ! cardiac muscle cell differentiation created_by: vk creation_date: 2011-06-08T10:51:15Z [Term] id: GO:2000729 name: positive regulation of mesenchymal cell proliferation involved in ureter development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development." [GOC:obol] synonym: "positive regulation of ureter mesenchymal cell proliferation" RELATED [GOC:obol] synonym: "positive regulation of ureteral mesenchymal cell proliferation" RELATED [GOC:obol] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0072199 ! regulation of mesenchymal cell proliferation involved in ureter development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development relationship: positively_regulates GO:0072198 ! mesenchymal cell proliferation involved in ureter development created_by: yaf creation_date: 2011-06-10T02:27:19Z [Term] id: GO:2000736 name: regulation of stem cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0048863 ! stem cell differentiation relationship: regulates GO:0048863 ! stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:16Z [Term] id: GO:2000737 name: negative regulation of stem cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0048863 ! stem cell differentiation relationship: negatively_regulates GO:0048863 ! stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:20Z [Term] id: GO:2000738 name: positive regulation of stem cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of stem cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2000736 ! regulation of stem cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0048863 ! stem cell differentiation relationship: positively_regulates GO:0048863 ! stem cell differentiation created_by: yaf creation_date: 2011-06-14T02:05:23Z [Term] id: GO:2000768 name: positive regulation of nephron tubule epithelial cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation." [GOC:obol] is_a: GO:0072182 ! regulation of nephron tubule epithelial cell differentiation is_a: GO:2000698 ! positive regulation of epithelial cell differentiation involved in kidney development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation relationship: positively_regulates GO:0072160 ! nephron tubule epithelial cell differentiation created_by: yaf creation_date: 2011-06-22T11:55:06Z [Term] id: GO:2000790 name: regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0010464 ! regulation of mesenchymal cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development relationship: regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:50Z [Term] id: GO:2000791 name: negative regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0051093 ! negative regulation of developmental process is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:0072201 ! negative regulation of mesenchymal cell proliferation is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development relationship: negatively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:53Z [Term] id: GO:2000792 name: positive regulation of mesenchymal cell proliferation involved in lung development namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development." [PMID:21513708] is_a: GO:0002053 ! positive regulation of mesenchymal cell proliferation is_a: GO:0051094 ! positive regulation of developmental process is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000790 ! regulation of mesenchymal cell proliferation involved in lung development intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development relationship: positively_regulates GO:0060916 ! mesenchymal cell proliferation involved in lung development created_by: pr creation_date: 2011-06-24T01:53:56Z [Term] id: GO:2000794 name: regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050678 ! regulation of epithelial cell proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis relationship: regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis created_by: pr creation_date: 2011-06-25T07:22:38Z [Term] id: GO:2000795 name: negative regulation of epithelial cell proliferation involved in lung morphogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis." [PMID:21513708] is_a: GO:0050680 ! negative regulation of epithelial cell proliferation is_a: GO:2000794 ! regulation of epithelial cell proliferation involved in lung morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis relationship: negatively_regulates GO:0060502 ! epithelial cell proliferation involved in lung morphogenesis created_by: pr creation_date: 2011-06-25T07:22:42Z [Term] id: GO:2000818 name: negative regulation of myoblast proliferation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation." [GOC:obol] is_a: GO:0008285 ! negative regulation of cell population proliferation is_a: GO:2000291 ! regulation of myoblast proliferation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051450 ! myoblast proliferation relationship: negatively_regulates GO:0051450 ! myoblast proliferation created_by: pr creation_date: 2011-07-12T03:06:04Z [Term] id: GO:2000826 name: regulation of heart morphogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of heart morphogenesis." [GOC:BHF] synonym: "regulation of cardiac morphogenesis" RELATED [GOC:obol] is_a: GO:2000027 ! regulation of animal organ morphogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0003007 ! heart morphogenesis relationship: regulates GO:0003007 ! heart morphogenesis created_by: vk creation_date: 2011-07-19T10:08:58Z [Term] id: GO:2000831 name: regulation of steroid hormone secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032368 ! regulation of lipid transport is_a: GO:0044060 ! regulation of endocrine process is_a: GO:0046883 ! regulation of hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035929 ! steroid hormone secretion relationship: regulates GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-26T08:38:46Z [Term] id: GO:2000832 name: negative regulation of steroid hormone secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032369 ! negative regulation of lipid transport is_a: GO:0046888 ! negative regulation of hormone secretion is_a: GO:0051241 ! negative regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035929 ! steroid hormone secretion relationship: negatively_regulates GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-26T08:38:50Z [Term] id: GO:2000833 name: positive regulation of steroid hormone secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion." [GOC:sl] is_a: GO:0032370 ! positive regulation of lipid transport is_a: GO:0046887 ! positive regulation of hormone secretion is_a: GO:0051240 ! positive regulation of multicellular organismal process is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035929 ! steroid hormone secretion relationship: positively_regulates GO:0035929 ! steroid hormone secretion created_by: bf creation_date: 2011-07-26T08:38:51Z [Term] id: GO:2000834 name: regulation of androgen secretion namespace: biological_process def: "Any process that modulates the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000831 ! regulation of steroid hormone secretion intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035935 ! androgen secretion relationship: regulates GO:0035935 ! androgen secretion created_by: bf creation_date: 2011-07-26T08:39:45Z [Term] id: GO:2000835 name: negative regulation of androgen secretion namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000832 ! negative regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035935 ! androgen secretion relationship: negatively_regulates GO:0035935 ! androgen secretion created_by: bf creation_date: 2011-07-26T08:39:48Z [Term] id: GO:2000836 name: positive regulation of androgen secretion namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of androgen secretion." [GOC:sl] is_a: GO:2000833 ! positive regulation of steroid hormone secretion is_a: GO:2000834 ! regulation of androgen secretion intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035935 ! androgen secretion relationship: positively_regulates GO:0035935 ! androgen secretion created_by: bf creation_date: 2011-07-26T08:39:51Z [Term] id: GO:2000977 name: regulation of forebrain neuron differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] is_a: GO:0045664 ! regulation of neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0021879 ! forebrain neuron differentiation relationship: regulates GO:0021879 ! forebrain neuron differentiation created_by: yaf creation_date: 2011-08-03T12:09:12Z [Term] id: GO:2000978 name: negative regulation of forebrain neuron differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] is_a: GO:0045665 ! negative regulation of neuron differentiation is_a: GO:2000977 ! regulation of forebrain neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0021879 ! forebrain neuron differentiation relationship: negatively_regulates GO:0021879 ! forebrain neuron differentiation created_by: yaf creation_date: 2011-08-03T12:09:16Z [Term] id: GO:2000979 name: positive regulation of forebrain neuron differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation." [GOC:obol] is_a: GO:0045666 ! positive regulation of neuron differentiation is_a: GO:2000977 ! regulation of forebrain neuron differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0021879 ! forebrain neuron differentiation relationship: positively_regulates GO:0021879 ! forebrain neuron differentiation created_by: yaf creation_date: 2011-08-03T12:09:19Z [Term] id: GO:2001012 name: mesenchymal cell differentiation involved in renal system development namespace: biological_process def: "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state." [GOC:mtg_kidney_jan10, GOC:obol, GOC:yaf] synonym: "mesenchymal cell differentiation involved in urinary system development" RELATED [GOC:obol] synonym: "mesenchymal cell differentiation involved in urinary tract development" RELATED [GOC:obol] is_a: GO:0048762 ! mesenchymal cell differentiation intersection_of: GO:0048762 ! mesenchymal cell differentiation intersection_of: part_of GO:0072001 ! renal system development relationship: part_of GO:0072001 ! renal system development created_by: yaf creation_date: 2011-08-09T04:05:14Z [Term] id: GO:2001013 name: epithelial cell proliferation involved in renal tubule morphogenesis namespace: biological_process def: "Any epithelial cell proliferation that is involved in renal tubule morphogenesis." [GOC:obol] is_a: GO:0050673 ! epithelial cell proliferation intersection_of: GO:0050673 ! epithelial cell proliferation intersection_of: part_of GO:0061333 ! renal tubule morphogenesis relationship: part_of GO:0061333 ! renal tubule morphogenesis created_by: yaf creation_date: 2011-08-12T11:37:29Z [Term] id: GO:2001014 name: regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035914 ! skeletal muscle cell differentiation relationship: regulates GO:0035914 ! skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:37Z [Term] id: GO:2001015 name: negative regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation relationship: negatively_regulates GO:0035914 ! skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:41Z [Term] id: GO:2001016 name: positive regulation of skeletal muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation." [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001014 ! regulation of skeletal muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035914 ! skeletal muscle cell differentiation relationship: positively_regulates GO:0035914 ! skeletal muscle cell differentiation created_by: yaf creation_date: 2011-08-11T08:54:44Z [Term] id: GO:2001017 name: regulation of retrograde axon cargo transport namespace: biological_process def: "Any process that modulates the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] synonym: "regulation of retrograde axonal transport" EXACT [GOC:obol] is_a: GO:0032386 ! regulation of intracellular transport is_a: GO:0060632 ! regulation of microtubule-based movement intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0008090 ! retrograde axonal transport relationship: regulates GO:0008090 ! retrograde axonal transport created_by: kmv creation_date: 2011-08-11T09:44:42Z [Term] id: GO:2001018 name: negative regulation of retrograde axon cargo transport namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] synonym: "negative regulation of retrograde axonal transport" EXACT [GOC:obol] is_a: GO:0032387 ! negative regulation of intracellular transport is_a: GO:2001017 ! regulation of retrograde axon cargo transport intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0008090 ! retrograde axonal transport relationship: negatively_regulates GO:0008090 ! retrograde axonal transport created_by: kmv creation_date: 2011-08-11T09:44:46Z [Term] id: GO:2001019 name: positive regulation of retrograde axon cargo transport namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport." [GOC:obol] synonym: "positive regulation of retrograde axonal transport" EXACT [GOC:obol] is_a: GO:0032388 ! positive regulation of intracellular transport is_a: GO:2001017 ! regulation of retrograde axon cargo transport intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0008090 ! retrograde axonal transport relationship: positively_regulates GO:0008090 ! retrograde axonal transport created_by: kmv creation_date: 2011-08-11T09:44:49Z [Term] id: GO:2001035 name: regulation of tongue muscle cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] is_a: GO:1902809 ! regulation of skeletal muscle fiber differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0035981 ! tongue muscle cell differentiation relationship: regulates GO:0035981 ! tongue muscle cell differentiation created_by: yaf creation_date: 2011-08-24T11:10:16Z [Term] id: GO:2001036 name: negative regulation of tongue muscle cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] is_a: GO:1902810 ! negative regulation of skeletal muscle fiber differentiation is_a: GO:2001035 ! regulation of tongue muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0035981 ! tongue muscle cell differentiation relationship: negatively_regulates GO:0035981 ! tongue muscle cell differentiation created_by: yaf creation_date: 2011-08-24T11:10:20Z [Term] id: GO:2001037 name: positive regulation of tongue muscle cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation." [GOC:obol] is_a: GO:1902811 ! positive regulation of skeletal muscle fiber differentiation is_a: GO:2001035 ! regulation of tongue muscle cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0035981 ! tongue muscle cell differentiation relationship: positively_regulates GO:0035981 ! tongue muscle cell differentiation created_by: yaf creation_date: 2011-08-24T11:10:22Z [Term] id: GO:2001053 name: regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097152 ! mesenchymal cell apoptotic process relationship: regulates GO:0097152 ! mesenchymal cell apoptotic process created_by: yaf creation_date: 2011-09-08T02:49:59Z [Term] id: GO:2001054 name: negative regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "negative regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process relationship: negatively_regulates GO:0097152 ! mesenchymal cell apoptotic process created_by: yaf creation_date: 2011-09-08T02:50:05Z [Term] id: GO:2001055 name: positive regulation of mesenchymal cell apoptotic process namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process." [GOC:mtg_apoptosis, GOC:obol] synonym: "positive regulation of mesenchymal cell apoptosis" NARROW [] is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001053 ! regulation of mesenchymal cell apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process relationship: positively_regulates GO:0097152 ! mesenchymal cell apoptotic process created_by: yaf creation_date: 2011-09-08T02:50:09Z [Term] id: GO:2001141 name: regulation of RNA biosynthetic process namespace: biological_process def: "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." [GOC:dph] synonym: "regulation of RNA anabolism" EXACT [GOC:obol] synonym: "regulation of RNA biosynthesis" EXACT [GOC:obol] synonym: "regulation of RNA formation" EXACT [GOC:obol] synonym: "regulation of RNA synthesis" EXACT [GOC:obol] is_a: GO:0010556 ! regulation of macromolecule biosynthetic process is_a: GO:0031326 ! regulation of cellular biosynthetic process is_a: GO:0051252 ! regulation of RNA metabolic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0032774 ! RNA biosynthetic process relationship: regulates GO:0032774 ! RNA biosynthetic process created_by: dph creation_date: 2011-10-17T11:36:25Z [Term] id: GO:2001198 name: regulation of dendritic cell differentiation namespace: biological_process def: "Any process that modulates the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902105 ! regulation of leukocyte differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097028 ! dendritic cell differentiation relationship: regulates GO:0097028 ! dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:27Z [Term] id: GO:2001199 name: negative regulation of dendritic cell differentiation namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902106 ! negative regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097028 ! dendritic cell differentiation relationship: negatively_regulates GO:0097028 ! dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:33Z [Term] id: GO:2001200 name: positive regulation of dendritic cell differentiation namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation." [GOC:obol] is_a: GO:1902107 ! positive regulation of leukocyte differentiation is_a: GO:2001198 ! regulation of dendritic cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097028 ! dendritic cell differentiation relationship: positively_regulates GO:0097028 ! dendritic cell differentiation created_by: yaf creation_date: 2011-11-04T02:01:36Z [Term] id: GO:2001212 name: regulation of vasculogenesis namespace: biological_process def: "Any process that modulates the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045595 ! regulation of cell differentiation intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001570 ! vasculogenesis relationship: regulates GO:0001570 ! vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:31Z [Term] id: GO:2001213 name: negative regulation of vasculogenesis namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "negative regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045596 ! negative regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001570 ! vasculogenesis relationship: negatively_regulates GO:0001570 ! vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:36Z [Term] id: GO:2001214 name: positive regulation of vasculogenesis namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of vasculogenesis." [GOC:obol] synonym: "positive regulation of vascular morphogenesis" EXACT [GOC:obol] is_a: GO:0045597 ! positive regulation of cell differentiation is_a: GO:2001212 ! regulation of vasculogenesis intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001570 ! vasculogenesis relationship: positively_regulates GO:0001570 ! vasculogenesis created_by: yaf creation_date: 2011-11-15T01:22:39Z [Term] id: GO:2001222 name: regulation of neuron migration namespace: biological_process def: "Any process that modulates the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "regulation of neuron guidance" RELATED [GOC:obol] synonym: "regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030334 ! regulation of cell migration intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0001764 ! neuron migration relationship: in_taxon NCBITaxon:33208 {all_only="true"} ! Metazoa relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: regulates GO:0001764 ! neuron migration created_by: kmv creation_date: 2011-11-17T10:01:38Z [Term] id: GO:2001223 name: negative regulation of neuron migration namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "negative regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "negative regulation of neuron guidance" RELATED [GOC:obol] synonym: "negative regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030336 ! negative regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0001764 ! neuron migration relationship: negatively_regulates GO:0001764 ! neuron migration created_by: kmv creation_date: 2011-11-17T10:01:45Z [Term] id: GO:2001224 name: positive regulation of neuron migration namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of neuron migration." [GOC:obol] synonym: "positive regulation of neuron chemotaxis" EXACT [GOC:obol] synonym: "positive regulation of neuron guidance" RELATED [GOC:obol] synonym: "positive regulation of neuronal migration" EXACT [GOC:obol] is_a: GO:0030335 ! positive regulation of cell migration is_a: GO:2001222 ! regulation of neuron migration intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0001764 ! neuron migration relationship: positively_regulates GO:0001764 ! neuron migration created_by: kmv creation_date: 2011-11-17T10:01:49Z [Term] id: GO:2001233 name: regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009966 ! regulation of signal transduction is_a: GO:0042981 ! regulation of apoptotic process intersection_of: GO:0065007 ! biological regulation intersection_of: regulates GO:0097190 ! apoptotic signaling pathway relationship: regulates GO:0097190 ! apoptotic signaling pathway created_by: pr creation_date: 2011-11-24T01:20:49Z [Term] id: GO:2001234 name: negative regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "negative regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009968 ! negative regulation of signal transduction is_a: GO:0043066 ! negative regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0097190 ! apoptotic signaling pathway relationship: negatively_regulates GO:0097190 ! apoptotic signaling pathway created_by: pr creation_date: 2011-11-24T01:20:54Z [Term] id: GO:2001235 name: positive regulation of apoptotic signaling pathway namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." [GOC:mtg_apoptosis] synonym: "positive regulation of apoptotic signalling pathway" EXACT [GOC:mah] is_a: GO:0009967 ! positive regulation of signal transduction is_a: GO:0043065 ! positive regulation of apoptotic process is_a: GO:2001233 ! regulation of apoptotic signaling pathway intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0097190 ! apoptotic signaling pathway relationship: positively_regulates GO:0097190 ! apoptotic signaling pathway created_by: pr creation_date: 2011-11-24T01:20:58Z [Term] id: GO:2001251 name: negative regulation of chromosome organization namespace: biological_process def: "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "negative regulation of chromosome organisation" EXACT [GOC:obol] synonym: "negative regulation of chromosome organization and biogenesis" RELATED [GOC:obol] synonym: "negative regulation of maintenance of genome integrity" RELATED [GOC:obol] synonym: "negative regulation of nuclear genome maintenance" RELATED [GOC:obol] is_a: GO:0010639 ! negative regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: negatively_regulates GO:0051276 ! chromosome organization relationship: negatively_regulates GO:0051276 ! chromosome organization created_by: yaf creation_date: 2011-12-02T02:01:20Z [Term] id: GO:2001252 name: positive regulation of chromosome organization namespace: biological_process def: "Any process that activates or increases the frequency, rate or extent of chromosome organization." [GOC:obol] synonym: "positive regulation of chromosome organisation" EXACT [GOC:obol] synonym: "positive regulation of chromosome organization and biogenesis" RELATED [GOC:obol] synonym: "positive regulation of maintenance of genome integrity" RELATED [GOC:obol] synonym: "positive regulation of nuclear genome maintenance" RELATED [GOC:obol] is_a: GO:0010638 ! positive regulation of organelle organization is_a: GO:0033044 ! regulation of chromosome organization intersection_of: GO:0065007 ! biological regulation intersection_of: positively_regulates GO:0051276 ! chromosome organization relationship: positively_regulates GO:0051276 ! chromosome organization created_by: yaf creation_date: 2011-12-02T02:01:26Z [Term] id: IAO:0000005 name: objective specification def: "A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved." [] is_a: IAO:0000033 ! directive information entity property_value: editor_note "2009-03-16: original definition when imported from OBI read: \"objective is an non realizable information entity which can serve as that proper part of a plan towards which the realization of the plan is directed.\"" xsd:string property_value: editor_note "2014-03-31: In the example of usage (\"In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction\") there is a protocol which is the ChIP assay protocol. In addition to being concretized on paper, the protocol can be concretized as a realizable entity, such as a plan that inheres in a person. The objective specification is the part that says that some protein and DNA interactions are identified. This is a specification of a process endpoint: the boundary in the process before which they are not identified and after which they are. During the realization of the plan, the goal is to get to the point of having the interactions, and participants in the realization of the plan try to do that." xsd:string property_value: editor_note "Answers the question, why did you do this experiment?" xsd:string property_value: IAO:0000111 "objective specification" xsd:string property_value: IAO:0000112 "In the protocol of a ChIP assay the objective specification says to identify protein and DNA interaction." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Barry Smith" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Jennifer Fostel" xsd:string property_value: IAO:0000118 "goal specification" xsd:string property_value: IAO:0000119 "OBI Plan and Planned Process/Roles Branch" xsd:string property_value: IAO:0000119 "OBI_0000217" xsd:string [Term] id: IAO:0000007 name: action specification def: "A directive information entity that describes an action the bearer will take." [] is_a: IAO:0000033 ! directive information entity property_value: IAO:0000112 "Pour the contents of flask 1 into flask 2" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "OBI Plan and Planned Process branch" xsd:string [Term] id: IAO:0000027 name: data item def: "a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." [] def: "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements." [] is_a: IAO:0000030 ! information content entity property_value: editor_note "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers." xsd:string property_value: editor_note "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum." xsd:string property_value: editor_note "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym." xsd:string property_value: editor_note "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/" xsd:string property_value: editor_note "JAR: datum -- well, this will be very tricky to define, but maybe some \ninformation-like stuff that might be put into a computer and that is \nmeant, by someone, to denote and/or to be interpreted by some \nprocess... I would include lists, tables, sentences... I think I might \ndefer to Barry, or to Brian Cantwell Smith\n\nJAR: A data item is an approximately justified approximately true approximate belief" xsd:string property_value: IAO:0000111 "data item" xsd:string property_value: IAO:0000112 "Data items include counts of things, analyte concentrations, and statistical summaries." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string property_value: IAO:0000117 "PERSON: Jonathan Rees" xsd:string property_value: IAO:0000118 "data" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl [Term] id: IAO:0000030 name: information content entity def: "A generically dependent continuant that is about some thing." [] is_a: BFO:0000031 ! generically dependent continuant relationship: IAO:0000136 BFO:0000001 ! is about entity property_value: editor_note "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)." xsd:string property_value: editor_note "information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907).\n\nPrevious. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity." xsd:string property_value: IAO:0000111 "information content entity" xsd:string property_value: IAO:0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Chris Stoeckert" xsd:string property_value: IAO:0000119 "OBI_0000142" xsd:string [Term] id: IAO:0000033 name: directive information entity def: "An information content entity whose concretizations indicate to their bearer how to realize them in a process." [] is_a: IAO:0000030 ! information content entity relationship: IAO:0000136 BFO:0000017 ! is about realizable entity property_value: editor_note "2009-03-16: provenance: a term realizable information entity was proposed for OBI (OBI_0000337) , edited by the PlanAndPlannedProcess branch. Original definition was \"is the specification of a process that can be concretized and realized by an actor\" with alternative term \"instruction\".It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term." xsd:string property_value: editor_note "2013-05-30 Alan Ruttenberg: What differentiates a directive information entity from an information concretization is that it can have concretizations that are either qualities or realizable entities. The concretizations that are realizable entities are created when an individual chooses to take up the direction, i.e. has the intention to (try to) realize it." xsd:string property_value: editor_note "8/6/2009 Alan Ruttenberg: Changed label from \"information entity about a realizable\" after discussions at ICBO" xsd:string property_value: editor_note "Werner pushed back on calling it realizable information entity as it isn't realizable. However this name isn't right either. An example would be a recipe. The realizable entity would be a plan, but the information entity isn't about the plan, it, once concretized, *is* the plan. -Alan" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string [Term] id: IAO:0000078 name: curation status specification def: "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: editor_note "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)" xsd:string property_value: IAO:0000111 "curation status specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON:Bill Bug" xsd:string property_value: IAO:0000119 "GROUP:OBI:" xsd:string property_value: IAO:0000119 "OBI_0000266" xsd:string [Term] id: IAO:0000102 name: data about an ontology part def: "Data about an ontology part is a data item about a part of an ontology, for example a term" [] def: "data about an ontology part is a data item about a part of an ontology, for example a term" [] is_a: IAO:0000027 ! data item property_value: IAO:0000111 "data about an ontology part" xsd:string property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string property_value: IAO:0000117 "Person:Alan Ruttenberg" xsd:string [Term] id: IAO:0000104 name: plan specification def: "A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified." [] comment: 2/3/2009 Comment from OBI review.\n\nAction specification not well enough specified.\nConditional specification not well enough specified.\nQuestion whether all plan specifications have objective specifications.\n\nRequest that IAO either clarify these or change definitions not to use them is_a: IAO:0000033 ! directive information entity relationship: has_part IAO:0000005 ! objective specification relationship: has_part IAO:0000007 ! action specification property_value: editor_note "2009-03-16: provenance: a term a plan was proposed for OBI (OBI_0000344) , edited by the PlanAndPlannedProcess branch. Original definition was \" a plan is a specification of a process that is realized by an actor to achieve the objective specified as part of the plan\". It has been subsequently moved to IAO where the objective for which the original term was defined was satisfied with the definitionof this, different, term." xsd:string property_value: editor_note "2014-03-31: A plan specification can have other parts, such as conditional specifications." xsd:string property_value: editor_note "Alternative previous definition: a plan is a set of instructions that specify how an objective should be achieved" xsd:string property_value: IAO:0000111 "plan specification" xsd:string property_value: IAO:0000112 "PMID: 18323827.Nat Med. 2008 Mar;14(3):226.New plan proposed to help resolve conflicting medical advice." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "OBI Plan and Planned Process branch" xsd:string property_value: IAO:0000119 "OBI_0000344" xsd:string [Term] id: IAO:0000178 name: material information bearer def: "A material entity in which a concretization of an information content entity inheres." [] is_a: BFO:0000040 ! material entity property_value: IAO:0000111 "material information bearer" xsd:string property_value: IAO:0000112 "a brain" xsd:string property_value: IAO:0000112 "a hard drive" xsd:string property_value: IAO:0000112 "A page of a paperback novel with writing on it. The paper itself is a material information bearer, the pattern of ink is the information carrier." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "GROUP: IAO" xsd:string [Term] id: IAO:0000225 name: obsolescence reason specification def: "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value." [] is_a: IAO:0000102 ! data about an ontology part property_value: editor_note "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology." xsd:string property_value: IAO:0000111 "obsolescence reason specification" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string [Term] id: IAO:0000409 name: denotator type def: "A denotator type indicates how a term should be interpreted from an ontological perspective." [] is_a: IAO:0000102 ! data about an ontology part property_value: IAO:0000111 "denotator type" xsd:string property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string property_value: IAO:0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities." xsd:string property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string property_value: IAO:0000119 "Barry Smith, Werner Ceusters" xsd:string [Term] id: NBO:0000001 name: body part movement namespace: behavior_ontology def: "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]" [] synonym: "stationary movement" EXACT [] is_a: NBO:0000338 ! kinesthetic behavior property_value: http://purl.org/dc/elements/1.1/date "2011-04-14T01:03:39Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000007 name: mouth movement namespace: behavior_ontology def: "The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC]" [] synonym: "mouth part movement" NARROW [] synonym: "other moved mouth parts" NARROW [] is_a: NBO:0000001 ! body part movement property_value: http://purl.org/dc/elements/1.1/date "2011-04-14T01:03:39Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000073 name: chewing namespace: behavior_ontology def: "The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]" [] synonym: "chew" EXACT [] synonym: "gnaw" EXACT [] synonym: "mastication" EXACT [] is_a: NBO:0000747 ! jaw movement property_value: http://purl.org/dc/elements/1.1/date "2011-04-14T01:20:02Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000313 name: behavior process namespace: behavior_ontology alt_id: NBO:0000000 def: "\"The action, reaction, or performance of an organism in response to external or internal stimuli.\" [GO:GO\\:0007610]" [] synonym: "behavior" EXACT [] synonym: "behaviour" EXACT [] xref: GO:0007610 is_a: GO:0007610 ! behavior property_value: http://purl.org/dc/elements/1.1/date "2011-04-05T09:53:10Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000338 name: kinesthetic behavior namespace: behavior_ontology def: "\"Movement behavior of the body or its parts.\"" [] is_a: NBO:0000313 ! behavior process property_value: http://purl.org/dc/elements/1.1/date "2011-04-05T02:08:47Z" xsd:string created_by: George Gkoutos [Term] id: NBO:0000747 name: jaw movement namespace: behavior_ontology is_a: NBO:0000007 ! mouth movement property_value: http://purl.org/dc/elements/1.1/date "2012-03-17T09:51:17Z" xsd:string created_by: gkoutos [Term] id: NBO:0001786 name: regulation of behavior def: "\"Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.\" [GO:0050795]" [] xref: GO:0050795 is_a: NBO:0000313 ! behavior process relationship: regulates NBO:0000313 ! behavior process created_by: George Gkoutos [Term] id: NCBITaxon:1 name: root namespace: ncbi_taxonomy synonym: "all" RELATED synonym [] xref: GC_ID:1 is_a: OBI:0100026 ! organism [Term] id: NCBITaxon:10066 name: Muridae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15371245 is_a: NCBITaxon:337687 ! Muroidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:10088 name: Mus namespace: ncbi_taxonomy synonym: "mice" EXACT common_name [] synonym: "mouse" EXACT common_name [] synonym: "Mus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:10090 name: Mus musculus namespace: ncbi_taxonomy alt_id: NCBITaxon:85055 synonym: "house mouse" EXACT genbank_common_name [] synonym: "mouse" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:862507 ! Mus property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:10114 name: Rattus namespace: ncbi_taxonomy synonym: "rat" EXACT common_name [] synonym: "rats" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:39107 ! Murinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:10239 name: Viruses is_a: OBI:0100026 ! organism property_value: IAO:0000111 "Viruses" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:105389 name: Sedentaria namespace: ncbi_taxonomy synonym: "Palpata" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6341 ! Polychaeta property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:105391 name: Canalipalpata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:105389 ! Sedentaria property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:110814 name: Xenoturbellida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:110815 name: Xenoturbella namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1547233 ! Xenoturbellidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:117565 name: Myxini namespace: ncbi_taxonomy synonym: "Agnatha" RELATED in_part [] synonym: "fish" EXACT common_name [] synonym: "fishes" EXACT common_name [] synonym: "Hyperotreti" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1476529 ! Cyclostomata property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:117569 name: Hyperoartia namespace: ncbi_taxonomy synonym: "Agnatha" RELATED in_part [] synonym: "Cephalaspidomorphi" RELATED in_part [] synonym: "fish" EXACT common_name [] synonym: "fishes" EXACT common_name [] synonym: "Monorhina" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:1476529 ! Cyclostomata property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:117570 name: Teleostomi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:117571 name: Euteleostomi namespace: ncbi_taxonomy alt_id: NCBITaxon:40673 synonym: "bony vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:117570 ! Teleostomi property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:119089 name: Chromadorea namespace: ncbi_taxonomy alt_id: NCBITaxon:27837 synonym: "Adenophorea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6231 ! Nematoda property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:1206794 name: Ecdysozoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1206795 name: Lophotrochozoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2697495 ! Spiralia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123365 name: Neoteleostei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489388 ! Euteleosteomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123366 name: Eurypterygia namespace: ncbi_taxonomy synonym: "Eurypterygii" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123365 ! Neoteleostei property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123367 name: Ctenosquamata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123366 ! Eurypterygia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123368 name: Acanthomorphata namespace: ncbi_taxonomy synonym: "Acanthomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123367 ! Ctenosquamata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:123369 name: Euacanthomorphacea namespace: ncbi_taxonomy synonym: "Euacanthomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:123368 ! Acanthomorphata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:124129 name: Acipenserinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7900 ! Acipenseridae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:124130 name: Acipenserini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:124129 ! Acipenserinae property_value: has_rank NCBITaxon:tribe [Term] id: NCBITaxon:131209 name: Zygnemophyceae namespace: ncbi_taxonomy synonym: "Conjugatophyceae" RELATED synonym [] synonym: "Gamophyceae" RELATED synonym [] synonym: "Gamophyta" RELATED synonym [] synonym: "gamophytes" EXACT common_name [] synonym: "Zygnematophyceae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:131221 ! Streptophytina property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:131221 name: Streptophytina namespace: ncbi_taxonomy synonym: "Charophyta/Embryophyta group" RELATED synonym [] synonym: "charophyte/embryophyte group" EXACT equivalent_name [] xref: GC_ID:1 is_a: NCBITaxon:35493 ! Streptophyta property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:1312402 name: Xenacoelomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:131567 name: cellular organisms namespace: ncbi_taxonomy synonym: "biota" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1 ! root property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:1329799 name: Archelosauria namespace: ncbi_taxonomy synonym: "Archosauria-Testudines" RELATED synonym [] synonym: "Testudines + Archosauria group" RELATED synonym [] xref: GC_ID:1 xref: PMID:22839753 xref: PMID:25450099 is_a: NCBITaxon:32561 ! Sauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1329911 name: Toxicofera namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:16286089 xref: PMID:19281946 xref: PMID:22982760 is_a: NCBITaxon:1329912 ! Episquamata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1329912 name: Episquamata namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:16286089 xref: PMID:22982760 is_a: NCBITaxon:1329950 ! Unidentata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1329950 name: Unidentata namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:22982760 is_a: NCBITaxon:1329961 ! Bifurcata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1329961 name: Bifurcata namespace: ncbi_taxonomy synonym: "split-tongued squamates" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:22982760 is_a: NCBITaxon:8509 ! Squamata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1338369 name: Dipnotetrapodomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8287 ! Sarcopterygii property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:142796 name: Eumycetozoa namespace: ncbi_taxonomy synonym: "Eumycetozoa Zopf, 1884" RELATED synonym [] synonym: "Mycetozoa" RELATED synonym [] synonym: "mycetozoans" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:9342353 is_a: NCBITaxon:2605435 ! Evosea property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:1437010 name: Boreoeutheria namespace: ncbi_taxonomy synonym: "Boreotheria" RELATED synonym [] xref: GC_ID:1 xref: PMID:11743200 xref: PMID:11791233 is_a: NCBITaxon:9347 ! Eutheria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1437180 name: Acrogymnospermae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:58024 ! Spermatophyta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1445966 name: Gnetidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:3372 ! Gnetopsida property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:147099 name: Acoelomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1312402 ! Xenacoelomorpha property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:147537 name: Saccharomycotina namespace: ncbi_taxonomy synonym: "true yeasts" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:716545 ! saccharomyceta property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:147554 name: Schizosaccharomycetes namespace: ncbi_taxonomy synonym: "Archiascomycota" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:451866 ! Taphrinomycotina property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:1476529 name: Cyclostomata namespace: ncbi_taxonomy synonym: "Agnatha" RELATED synonym [] synonym: "jawless vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1489340 name: Elopocephalai namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32443 ! Teleostei property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1489341 name: Osteoglossocephalai namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32443 ! Teleostei property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1489388 name: Euteleosteomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala property_value: has_rank NCBITaxon:cohort [Term] id: NCBITaxon:1489872 name: Percomorphaceae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:123369 ! Euacanthomorphacea property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1489922 name: Eupercaria namespace: ncbi_taxonomy synonym: "Percomorpharia" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1489872 ! Percomorphaceae property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:1547233 name: Xenoturbellidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:110814 ! Xenoturbellida property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:182222 name: Muraeninae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:46660 ! Muraenidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:186622 name: Acipenseroidei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7899 ! Acipenseriformes property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:186623 name: Actinopteri namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7898 ! Actinopterygii property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:186624 name: Elopocephala namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489340 ! Elopocephalai property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:186625 name: Clupeocephala namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1489341 ! Osteoglossocephalai [Term] id: NCBITaxon:186626 name: Otophysi namespace: ncbi_taxonomy synonym: "Otophysa" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:32519 ! Ostariophysi property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:186627 name: Cypriniphysae namespace: ncbi_taxonomy synonym: "Cypriniphysi" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186626 ! Otophysi property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:186634 name: Otomorpha namespace: ncbi_taxonomy synonym: "Ostarioclupeomorpha" RELATED synonym [] synonym: "Otocephala" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186625 ! Clupeocephala property_value: has_rank NCBITaxon:cohort [Term] id: NCBITaxon:189497 name: Echidna namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:182222 ! Muraeninae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:1963758 name: Myomorpha namespace: ncbi_taxonomy synonym: "mice and others" EXACT genbank_common_name [] synonym: "Sciurognathi" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:9989 ! Rodentia property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:197562 name: Pancrustacea namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:10874751 xref: PMID:11557979 is_a: NCBITaxon:197563 ! Mandibulata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:197563 name: Mandibulata namespace: ncbi_taxonomy synonym: "mandibulates" EXACT common_name [] xref: GC_ID:1 xref: PMID:11557979 xref: PMID:9727836 is_a: NCBITaxon:6656 ! Arthropoda property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:2 name: Bacteria namespace: ncbi_taxonomy synonym: "bacteria" RELATED blast_name [] synonym: "eubacteria" EXACT genbank_common_name [] synonym: "Monera" RELATED in_part [] synonym: "Procaryotae" RELATED in_part [] synonym: "Prokaryota" RELATED in_part [] synonym: "Prokaryotae" RELATED in_part [] synonym: "prokaryote" RELATED in_part [] synonym: "prokaryotes" RELATED in_part [] xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11542017 xref: PMID:11542087 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:270744 xref: PMID:7520741 xref: PMID:8123559 xref: PMID:8186100 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms property_value: has_rank NCBITaxon:superkingdom property_value: IAO:0000111 "Bacteria" xsd:string property_value: IAO:0000118 "eubacteria" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:2058185 name: Dictyosteliaceae namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:2058949 ! Dictyosteliales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:2058949 name: Dictyosteliales namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:33083 ! Dictyostelia property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:207598 name: Homininae namespace: ncbi_taxonomy synonym: "Homo/Pan/Gorilla group" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:9604 ! Hominidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:2157 name: Archaea namespace: ncbi_taxonomy synonym: "archaea" RELATED blast_name [] synonym: "Archaebacteria" RELATED synonym [] synonym: "Mendosicutes" RELATED synonym [] synonym: "Metabacteria" RELATED synonym [] synonym: "Monera" RELATED in_part [] synonym: "Procaryotae" RELATED in_part [] synonym: "Prokaryota" RELATED in_part [] synonym: "Prokaryotae" RELATED in_part [] synonym: "prokaryote" RELATED in_part [] synonym: "prokaryotes" RELATED in_part [] xref: GC_ID:11 xref: PMID:10425795 xref: PMID:10425796 xref: PMID:10425797 xref: PMID:10490293 xref: PMID:10843050 xref: PMID:10939651 xref: PMID:10939673 xref: PMID:10939677 xref: PMID:11211268 xref: PMID:11321083 xref: PMID:11321113 xref: PMID:11411719 xref: PMID:11540071 xref: PMID:11541975 xref: PMID:11542064 xref: PMID:11542149 xref: PMID:11760965 xref: PMID:12054223 xref: PMID:2112744 xref: PMID:25527841 xref: PMID:270744 xref: PMID:8123559 xref: PMID:8590690 xref: PMID:9103655 xref: PMID:9336922 is_a: NCBITaxon:131567 ! cellular organisms property_value: has_rank NCBITaxon:superkingdom property_value: IAO:0000111 "Archaea" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:2301116 name: Rhabditina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6236 ! Rhabditida property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:2301119 name: Rhabditomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2301116 ! Rhabditina property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:2605435 name: Evosea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:554915 ! Amoebozoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:2611352 name: Discoba namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:262014 name: Xenopus namespace: ncbi_taxonomy synonym: "Xenopus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:8353 ! Xenopus property_value: has_rank NCBITaxon:subgenus [Term] id: NCBITaxon:2653789 name: Whippomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:2684882 name: Zygnematophycidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:131209 ! Zygnemophyceae property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:2697495 name: Spiralia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33317 ! Protostomia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:2698737 name: Sar namespace: ncbi_taxonomy synonym: "SAR supergroup" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:2743709 name: Danionidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:30727 ! Cyprinoidei property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:2743711 name: Danioninae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2743709 ! Danionidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:2759 name: Eukaryota namespace: ncbi_taxonomy synonym: "Eucarya" RELATED synonym [] synonym: "Eucaryotae" RELATED synonym [] synonym: "eucaryotes" EXACT genbank_common_name [] synonym: "Eukarya" RELATED synonym [] synonym: "Eukaryotae" RELATED synonym [] synonym: "eukaryotes" EXACT common_name [] synonym: "eukaryotes" RELATED blast_name [] xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:131567 ! cellular organisms property_value: has_rank NCBITaxon:superkingdom property_value: IAO:0000111 "Eukaryota" xsd:string property_value: IAO:0000118 "eucaryotes" xsd:string property_value: IAO:0000118 "eukaryotes" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/ncbitaxon.owl property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:27592 name: Bovinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9895 ! Bovidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:2841271 name: Testudinata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1329799 ! Archelosauria property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:30319 name: Pipoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8342 ! Anura property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:30727 name: Cyprinoidei namespace: ncbi_taxonomy synonym: "Cyprinoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7952 ! Cypriniformes property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:31022 name: Tetraodontiformes namespace: ncbi_taxonomy synonym: "pufferfishes and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1489922 ! Eupercaria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:31028 name: Tetraodontoidei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31022 ! Tetraodontiformes property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:31031 name: Tetraodontidae namespace: ncbi_taxonomy synonym: "puffer fishes" EXACT common_name [] synonym: "puffers" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32517 ! Tetradontoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:31032 name: Takifugu namespace: ncbi_taxonomy synonym: "Fugu" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:31031 ! Tetraodontidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:31033 name: Takifugu rubripes namespace: ncbi_taxonomy synonym: "Fugu rubripes" RELATED synonym [] synonym: "Sphaeroides rubripes" RELATED synonym [] synonym: "Tetraodon rubripes" RELATED synonym [] synonym: "tiger puffer" EXACT common_name [] synonym: "torafugu" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:31032 ! Takifugu property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:311790 name: Afrotheria namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11114173 xref: PMID:11214319 xref: PMID:12128031 xref: PMID:12878460 xref: PMID:15306319 xref: PMID:9214502 xref: PMID:9667998 is_a: NCBITaxon:9347 ! Eutheria property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:314145 name: Laurasiatheria namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11214318 xref: PMID:11214319 xref: PMID:12878460 is_a: NCBITaxon:1437010 ! Boreoeutheria property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:314146 name: Euarchontoglires namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:12878460 xref: PMID:15522813 is_a: NCBITaxon:1437010 ! Boreoeutheria property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:314147 name: Glires namespace: ncbi_taxonomy synonym: "Rodents and rabbits" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:11214319 xref: PMID:12082125 xref: PMID:15522813 is_a: NCBITaxon:314146 ! Euarchontoglires property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:314293 name: Simiiformes namespace: ncbi_taxonomy synonym: "Anthropoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:376913 ! Haplorrhini property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:314295 name: Hominoidea namespace: ncbi_taxonomy synonym: "ape" EXACT common_name [] synonym: "apes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9526 ! Catarrhini property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:3176 name: Zygnematales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2684882 ! Zygnematophycidae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:3193 name: Embryophyta namespace: ncbi_taxonomy synonym: "higher plants" EXACT common_name [] synonym: "land plants" EXACT common_name [] synonym: "land plants" RELATED blast_name [] synonym: "plants" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:131221 ! Streptophytina property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32341 name: Sophophora namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7215 ! Drosophila property_value: has_rank NCBITaxon:subgenus [Term] id: NCBITaxon:32346 name: melanogaster group namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32341 ! Sophophora property_value: has_rank NCBITaxon:species_group [Term] id: NCBITaxon:32351 name: melanogaster subgroup namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:32346 ! melanogaster group property_value: has_rank NCBITaxon:species_subgroup [Term] id: NCBITaxon:32440 name: Chondrostei namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:32443 name: Teleostei namespace: ncbi_taxonomy synonym: "teleost fishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:41665 ! Neopterygii property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:32517 name: Tetradontoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:31028 ! Tetraodontoidei property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:32519 name: Ostariophysi namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186634 ! Otomorpha property_value: has_rank NCBITaxon:subcohort [Term] id: NCBITaxon:32521 name: Elopomorpha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:186624 ! Elopocephala property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32523 name: Tetrapoda namespace: ncbi_taxonomy synonym: "tetrapods" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32524 name: Amniota namespace: ncbi_taxonomy synonym: "amniotes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32525 name: Theria namespace: ncbi_taxonomy synonym: "Theria" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:32561 name: Sauria namespace: ncbi_taxonomy synonym: "Diapsida" RELATED synonym [] synonym: "diapsids" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8457 ! Sauropsida property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33083 name: Dictyostelia namespace: ncbi_taxonomy synonym: "cellular slime molds" RELATED blast_name [] synonym: "dictyostelid cellular slime molds" EXACT genbank_common_name [] synonym: "Dictyostelida" RELATED synonym [] synonym: "Dictyostelids" RELATED synonym [] synonym: "Dictyosteliida" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:29367151 xref: PMID:9342353 is_a: NCBITaxon:142796 ! Eumycetozoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33090 name: Viridiplantae namespace: ncbi_taxonomy synonym: "Chlorobionta" RELATED synonym [] synonym: "Chlorophyta/Embryophyta group" EXACT equivalent_name [] synonym: "chlorophyte/embryophyte group" EXACT equivalent_name [] synonym: "Chloroplastida" RELATED synonym [] synonym: "green plants" EXACT common_name [] synonym: "green plants" RELATED blast_name [] xref: GC_ID:1 xref: PMID:16248873 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:kingdom [Term] id: NCBITaxon:3312 name: Coniferophyta namespace: ncbi_taxonomy synonym: "conifers" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1437180 ! Acrogymnospermae property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33154 name: Opisthokonta namespace: ncbi_taxonomy synonym: "Fungi/Metazoa group" RELATED synonym [] synonym: "opisthokonts" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:clade property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:33208 name: Metazoa namespace: ncbi_taxonomy synonym: "Animalia" RELATED synonym [] synonym: "animals" RELATED blast_name [] synonym: "metazoans" EXACT genbank_common_name [] synonym: "multicellular animals" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:33154 ! Opisthokonta property_value: has_rank NCBITaxon:kingdom property_value: isDefinedBy http://purl.obolibrary.org/obo/ncbitaxon.owl [Term] id: NCBITaxon:33213 name: Bilateria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33317 name: Protostomia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33340 name: Neoptera namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7496 ! Pterygota property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:33392 name: Endopterygota namespace: ncbi_taxonomy synonym: "Holometabola" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:33340 ! Neoptera property_value: has_rank NCBITaxon:cohort [Term] id: NCBITaxon:33511 name: Deuterostomia namespace: ncbi_taxonomy synonym: "deuterostomes" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:33213 ! Bilateria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33554 name: Carnivora namespace: ncbi_taxonomy synonym: "carnivores" EXACT genbank_common_name [] synonym: "carnivores" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314145 ! Laurasiatheria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:33630 name: Alveolata namespace: ncbi_taxonomy synonym: "alveolates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:2698737 ! Sar property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:33682 name: Euglenozoa namespace: ncbi_taxonomy synonym: "Euglenozoans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2611352 ! Discoba property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:3372 name: Gnetopsida namespace: ncbi_taxonomy synonym: "Chlamydospermopsida" RELATED synonym [] synonym: "Gneticae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:1437180 ! Acrogymnospermae property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:337687 name: Muroidea namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15019624 xref: PMID:15371245 is_a: NCBITaxon:1963758 ! Myomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:3378 name: Gnetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1445966 ! Gnetidae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:338152 name: Felinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9681 ! Felidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:3398 name: Magnoliopsida namespace: ncbi_taxonomy synonym: "Angiospermae" RELATED synonym [] synonym: "angiosperms" EXACT common_name [] synonym: "flowering plants" EXACT genbank_common_name [] synonym: "flowering plants" RELATED blast_name [] synonym: "Magnoliophyta" RELATED synonym [] xref: GC_ID:1 xref: PMID:25249442 is_a: NCBITaxon:58024 ! Spermatophyta property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:34346 name: Schizosaccharomycetales namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:147554 ! Schizosaccharomycetes property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:34878 name: Cervinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9850 ! Cervidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:35493 name: Streptophyta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33090 ! Viridiplantae property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:35497 name: Suina namespace: ncbi_taxonomy synonym: "Suiformes" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:35500 name: Pecora namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9845 ! Ruminantia property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:376913 name: Haplorrhini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9443 ! Primates property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:379583 name: Feliformia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33554 ! Carnivora property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:379584 name: Caniformia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33554 ! Carnivora property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:38254 name: Glaucocystophyceae namespace: ncbi_taxonomy synonym: "algae" RELATED in_part [] synonym: "glaucocystophytes" EXACT common_name [] synonym: "Glaucophyceae" RELATED synonym [] synonym: "Glaucophyta" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:39107 name: Murinae namespace: ncbi_taxonomy alt_id: NCBITaxon:109679 xref: GC_ID:1 is_a: NCBITaxon:10066 ! Muridae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:40674 name: Mammalia namespace: ncbi_taxonomy synonym: "mammals" EXACT genbank_common_name [] synonym: "mammals" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:41324 name: Siboglinidae namespace: ncbi_taxonomy alt_id: NCBITaxon:167797 alt_id: NCBITaxon:27906 alt_id: NCBITaxon:29174 alt_id: NCBITaxon:41329 alt_id: NCBITaxon:54122 alt_id: NCBITaxon:55674 alt_id: NCBITaxon:55678 alt_id: NCBITaxon:6422 synonym: "Frenulata" RELATED synonym [] synonym: "Lamellibrachiidae" RELATED synonym [] synonym: "Obturata" RELATED synonym [] synonym: "Oligobrachiidae" RELATED synonym [] synonym: "Perviata" RELATED synonym [] synonym: "Pogonophora" RELATED synonym [] synonym: "pogonophores" EXACT common_name [] synonym: "Polybrachiidae" RELATED synonym [] synonym: "Sclerolinidae" RELATED synonym [] synonym: "tube worms" RELATED blast_name [] synonym: "Vestimentifera" RELATED synonym [] synonym: "vestimentiferans" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:6362 ! Sabellida property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:41665 name: Neopterygii namespace: ncbi_taxonomy synonym: "Neopterygi" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:186623 ! Actinopteri property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:41666 name: Batrachia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8292 ! Amphibia property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:436486 name: Dinosauria namespace: ncbi_taxonomy synonym: "dinosaur" EXACT common_name [] synonym: "dinosaurs" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:8492 ! Archosauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:436489 name: Saurischia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436486 ! Dinosauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:436491 name: Theropoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436489 ! Saurischia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:436492 name: Coelurosauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:436491 ! Theropoda property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:43733 name: Muscomorpha namespace: ncbi_taxonomy alt_id: NCBITaxon:43732 synonym: "Asilomorpha" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7203 ! Brachycera property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:43738 name: Schizophora namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:480117 ! Cyclorrhapha [Term] id: NCBITaxon:43741 name: Acalyptratae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43738 ! Schizophora [Term] id: NCBITaxon:43746 name: Ephydroidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43741 ! Acalyptratae property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:43845 name: Drosophilinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7214 ! Drosophilidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:451864 name: Dikarya namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:15689432 xref: PMID:16151185 xref: PMID:17010206 xref: PMID:17051209 xref: PMID:17572334 is_a: NCBITaxon:4751 ! Fungi property_value: has_rank NCBITaxon:subkingdom [Term] id: NCBITaxon:451866 name: Taphrinomycotina namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:46660 name: Muraenidae namespace: ncbi_taxonomy synonym: "moray eels" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7933 ! Anguilliformes property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:46877 name: Drosophilini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43845 ! Drosophilinae property_value: has_rank NCBITaxon:tribe [Term] id: NCBITaxon:4751 name: Fungi namespace: ncbi_taxonomy synonym: "fungi" RELATED blast_name [] synonym: "Mycota" RELATED synonym [] xref: GC_ID:1 xref: PMID:11062127 xref: PMID:12684019 is_a: NCBITaxon:33154 ! Opisthokonta property_value: has_rank NCBITaxon:kingdom [Term] id: NCBITaxon:480117 name: Cyclorrhapha namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:480118 ! Eremoneura property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:480118 name: Eremoneura namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:43733 ! Muscomorpha property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:4890 name: Ascomycota namespace: ncbi_taxonomy synonym: "ascomycete fungi" RELATED blast_name [] synonym: "ascomycetes" EXACT genbank_common_name [] synonym: "sac fungi" EXACT common_name [] xref: GC_ID:1 xref: PMID:17572334 is_a: NCBITaxon:451864 ! Dikarya property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:4891 name: Saccharomycetes namespace: ncbi_taxonomy synonym: "Hemiascomycetes" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:147537 ! Saccharomycotina property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:4892 name: Saccharomycetales namespace: ncbi_taxonomy synonym: "budding yeasts" RELATED blast_name [] synonym: "Endomycetales" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4891 ! Saccharomycetes property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:4893 name: Saccharomycetaceae namespace: ncbi_taxonomy alt_id: NCBITaxon:221665 alt_id: NCBITaxon:44280 xref: GC_ID:1 is_a: NCBITaxon:4892 ! Saccharomycetales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:4894 name: Schizosaccharomycetaceae namespace: ncbi_taxonomy synonym: "fission yeasts" EXACT genbank_common_name [] synonym: "Schizosaccharomycetoideae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:34346 ! Schizosaccharomycetales property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:4895 name: Schizosaccharomyces namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4894 ! Schizosaccharomycetaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:4896 name: Schizosaccharomyces pombe namespace: ncbi_taxonomy alt_id: NCBITaxon:45042 synonym: "fission yeast" EXACT genbank_common_name [] synonym: "Schizosaccharomyces malidevorans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4895 ! Schizosaccharomyces property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:4930 name: Saccharomyces namespace: ncbi_taxonomy alt_id: NCBITaxon:36915 synonym: "Pachytichospora" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4893 ! Saccharomycetaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:4932 name: Saccharomyces cerevisiae namespace: ncbi_taxonomy synonym: "baker's yeast" EXACT genbank_common_name [] synonym: "brewer's yeast" EXACT common_name [] synonym: "Candida robusta" RELATED synonym [] synonym: "Mycoderma cerevisiae" RELATED synonym [] synonym: "S. cerevisiae" EXACT common_name [] synonym: "Saccharomyces capensis" RELATED synonym [] synonym: "Saccharomyces italicus" RELATED synonym [] synonym: "Saccharomyces oviformis" RELATED synonym [] synonym: "Saccharomyces uvarum var. melibiosus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:4930 ! Saccharomyces property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:50557 name: Insecta namespace: ncbi_taxonomy synonym: "insects" RELATED blast_name [] synonym: "true insects" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:6960 ! Hexapoda property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:554915 name: Amoebozoa namespace: ncbi_taxonomy xref: GC_ID:1 xref: PMID:23020233 xref: PMID:30257078 is_a: NCBITaxon:2759 ! Eukaryota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:55879 name: Rhabditoidea namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:2301119 ! Rhabditomorpha property_value: has_rank NCBITaxon:superfamily [Term] id: NCBITaxon:55885 name: Peloderinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:6243 ! Rhabditidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:5782 name: Dictyostelium namespace: ncbi_taxonomy synonym: "Hyalostilbum" RELATED synonym [] xref: GC_ID:1 xref: PMID:29367151 is_a: NCBITaxon:2058185 ! Dictyosteliaceae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:58023 name: Tracheophyta namespace: ncbi_taxonomy synonym: "vascular plants" EXACT common_name [] synonym: "vascular plants" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:3193 ! Embryophyta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:58024 name: Spermatophyta namespace: ncbi_taxonomy synonym: "seed plants" EXACT common_name [] synonym: "seed plants" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:78536 ! Euphyllophyta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:6040 name: Porifera namespace: ncbi_taxonomy synonym: "Parazoa" RELATED synonym [] synonym: "sponges" EXACT genbank_common_name [] synonym: "sponges" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6072 name: Eumetazoa namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:33208 ! Metazoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:6073 name: Cnidaria namespace: ncbi_taxonomy synonym: "cnidarians" EXACT genbank_common_name [] synonym: "cnidarians" RELATED blast_name [] synonym: "Coelenterata" RELATED in_part [] synonym: "coelenterates" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:6072 ! Eumetazoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6157 name: Platyhelminthes namespace: ncbi_taxonomy synonym: "flatworm" EXACT common_name [] synonym: "flatworms" EXACT genbank_common_name [] synonym: "flatworms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6231 name: Nematoda namespace: ncbi_taxonomy synonym: "Nemata" RELATED synonym [] synonym: "nematode" EXACT common_name [] synonym: "nematodes" EXACT common_name [] synonym: "nematodes" RELATED blast_name [] synonym: "roundworm" EXACT common_name [] synonym: "roundworms" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6236 name: Rhabditida namespace: ncbi_taxonomy alt_id: NCBITaxon:33251 xref: GC_ID:1 is_a: NCBITaxon:119089 ! Chromadorea property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:6237 name: Caenorhabditis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:55885 ! Peloderinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:6239 name: Caenorhabditis elegans namespace: ncbi_taxonomy synonym: "Rhabditis elegans" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:6237 ! Caenorhabditis property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:6243 name: Rhabditidae namespace: ncbi_taxonomy alt_id: NCBITaxon:54603 xref: GC_ID:1 is_a: NCBITaxon:55879 ! Rhabditoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:6340 name: Annelida namespace: ncbi_taxonomy synonym: "annelid worms" EXACT genbank_common_name [] synonym: "segmented worms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:1206795 ! Lophotrochozoa property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6341 name: Polychaeta namespace: ncbi_taxonomy synonym: "polychaetes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:6340 ! Annelida property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:6362 name: Sabellida namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:105391 ! Canalipalpata property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:6656 name: Arthropoda namespace: ncbi_taxonomy synonym: "arthropods" EXACT genbank_common_name [] synonym: "arthropods" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:88770 ! Panarthropoda property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:6960 name: Hexapoda namespace: ncbi_taxonomy synonym: "Atelocerata" RELATED in_part [] synonym: "hexapods" RELATED blast_name [] synonym: "insects" EXACT genbank_common_name [] synonym: "Tracheata" RELATED in_part [] synonym: "Uniramia" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:197562 ! Pancrustacea property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:7147 name: Diptera namespace: ncbi_taxonomy synonym: "flies" EXACT genbank_common_name [] synonym: "flies" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33392 ! Endopterygota property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:716545 name: saccharomyceta namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:4890 ! Ascomycota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7203 name: Brachycera namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7147 ! Diptera property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:7214 name: Drosophilidae namespace: ncbi_taxonomy synonym: "pomace flies" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:43746 ! Ephydroidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:7215 name: Drosophila namespace: ncbi_taxonomy alt_id: NCBITaxon:7326 synonym: "Drosophila" EXACT scientific_name [] synonym: "fruit flies" EXACT genbank_common_name [] synonym: "fruit fly" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:46877 ! Drosophilini property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:7227 name: Drosophila melanogaster namespace: ncbi_taxonomy alt_id: NCBITaxon:2267365 synonym: "fruit fly" EXACT genbank_common_name [] synonym: "Sophophora melanogaster" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:32351 ! melanogaster subgroup property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:7496 name: Pterygota namespace: ncbi_taxonomy synonym: "Pterygota" EXACT scientific_name [] synonym: "winged insects" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:85512 ! Dicondylia property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:7586 name: Echinodermata namespace: ncbi_taxonomy synonym: "echinoderms" EXACT genbank_common_name [] synonym: "echinoderms" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33511 ! Deuterostomia property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:7711 name: Chordata namespace: ncbi_taxonomy synonym: "chordates" EXACT genbank_common_name [] synonym: "chordates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:33511 ! Deuterostomia property_value: has_rank NCBITaxon:phylum [Term] id: NCBITaxon:7712 name: Tunicata namespace: ncbi_taxonomy synonym: "tunicates" EXACT genbank_common_name [] synonym: "tunicates" RELATED blast_name [] synonym: "Urochordata" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:7742 name: Vertebrata namespace: ncbi_taxonomy synonym: "Vertebrata" EXACT scientific_name [] synonym: "vertebrates" EXACT genbank_common_name [] synonym: "vertebrates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:89593 ! Craniata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7745 name: Petromyzontiformes namespace: ncbi_taxonomy synonym: "lampreys" RELATED blast_name [] synonym: "Petromyzoniformes" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:117569 ! Hyperoartia property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7761 name: Myxiniformes namespace: ncbi_taxonomy synonym: "hagfishes" RELATED blast_name [] synonym: "Myxinoidea" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:117565 ! Myxini property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7762 name: Myxinidae namespace: ncbi_taxonomy synonym: "hagfishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7761 ! Myxiniformes property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:7776 name: Gnathostomata namespace: ncbi_taxonomy synonym: "Gnathostomata" EXACT scientific_name [] synonym: "jawed vertebrates" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7742 ! Vertebrata property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7777 name: Chondrichthyes namespace: ncbi_taxonomy synonym: "cartilaginous fishes" EXACT genbank_common_name [] synonym: "cartilaginous fishes" RELATED blast_name [] synonym: "fish" EXACT common_name [] synonym: "fishes" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:7776 ! Gnathostomata property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:7778 name: Elasmobranchii namespace: ncbi_taxonomy synonym: "elasmobranchs" EXACT genbank_common_name [] synonym: "sharks and rays" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:7777 ! Chondrichthyes property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:78536 name: Euphyllophyta namespace: ncbi_taxonomy synonym: "euphyllophytes" EXACT equivalent_name [] xref: GC_ID:1 is_a: NCBITaxon:58023 ! Tracheophyta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:7863 name: Holocephali namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:7777 ! Chondrichthyes property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:7864 name: Chimaeriformes namespace: ncbi_taxonomy synonym: "chimaeras" EXACT genbank_common_name [] synonym: "chimaeras" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:7863 ! Holocephali property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7878 name: Dipnomorpha namespace: ncbi_taxonomy synonym: "Choanichthyes" RELATED in_part [] synonym: "Dipneusti" RELATED synonym [] synonym: "dipnoans" EXACT common_name [] synonym: "Dipnoi" RELATED synonym [] synonym: "fish" EXACT common_name [] synonym: "fishes" EXACT common_name [] synonym: "lungfishes" EXACT genbank_common_name [] synonym: "lungfishes" RELATED blast_name [] synonym: "Osteichthyes" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:1338369 ! Dipnotetrapodomorpha property_value: has_rank NCBITaxon:subclass [Term] id: NCBITaxon:7898 name: Actinopterygii namespace: ncbi_taxonomy synonym: "Actinopterygi" RELATED synonym [] synonym: "bony fishes" RELATED blast_name [] synonym: "fish" EXACT common_name [] synonym: "fishes" EXACT common_name [] synonym: "Osteichthyes" RELATED in_part [] synonym: "ray-finned fishes" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi property_value: has_rank NCBITaxon:superclass [Term] id: NCBITaxon:7899 name: Acipenseriformes namespace: ncbi_taxonomy synonym: "sturgeons and paddlefish" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32440 ! Chondrostei property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7900 name: Acipenseridae namespace: ncbi_taxonomy synonym: "sturgeons" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:186622 ! Acipenseroidei property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:7901 name: Acipenser namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:124130 ! Acipenserini property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:7933 name: Anguilliformes namespace: ncbi_taxonomy alt_id: NCBITaxon:30678 synonym: "true eels" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32521 ! Elopomorpha property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7952 name: Cypriniformes namespace: ncbi_taxonomy synonym: "carps and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:186627 ! Cypriniphysae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:7954 name: Danio namespace: ncbi_taxonomy alt_id: NCBITaxon:46777 alt_id: NCBITaxon:487617 synonym: "Brachydanio" RELATED synonym [] synonym: "Celestichthys" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:2743711 ! Danioninae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:7955 name: Danio rerio namespace: ncbi_taxonomy alt_id: NCBITaxon:27702 alt_id: NCBITaxon:37966 synonym: "Brachydanio rerio" RELATED synonym [] synonym: "Brachydanio rerio frankei" RELATED synonym [] synonym: "Cyprinus rerio" RELATED synonym [] synonym: "Danio frankei" RELATED synonym [] synonym: "Danio rerio frankei" RELATED synonym [] synonym: "leopard danio" EXACT common_name [] synonym: "zebra danio" EXACT common_name [] synonym: "zebra fish" EXACT common_name [] synonym: "zebrafish" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:7954 ! Danio property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:8287 name: Sarcopterygii namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:117571 ! Euteleostomi property_value: has_rank NCBITaxon:superclass [Term] id: NCBITaxon:8292 name: Amphibia namespace: ncbi_taxonomy synonym: "amphibians" EXACT genbank_common_name [] synonym: "amphibians" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32523 ! Tetrapoda property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:8342 name: Anura namespace: ncbi_taxonomy synonym: "anurans" EXACT common_name [] synonym: "frogs" EXACT common_name [] synonym: "frogs & toads" RELATED blast_name [] synonym: "frogs and toads" EXACT genbank_common_name [] synonym: "Salientia" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:41666 ! Batrachia property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8352 name: Pipidae namespace: ncbi_taxonomy synonym: "pipid frogs" EXACT common_name [] synonym: "tongueless frogs" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:30319 ! Pipoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:8353 name: Xenopus namespace: ncbi_taxonomy synonym: "Xenopus" EXACT scientific_name [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8360 ! Xenopodinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:8355 name: Xenopus laevis namespace: ncbi_taxonomy synonym: "African clawed frog" EXACT genbank_common_name [] synonym: "Bufo laevis" RELATED synonym [] synonym: "clawed frog" EXACT common_name [] synonym: "common platanna" EXACT common_name [] synonym: "platanna" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:262014 ! Xenopus property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:8360 name: Xenopodinae namespace: ncbi_taxonomy synonym: "Siluraninae" RELATED synonym [] xref: GC_ID:1 xref: PMID:2385174 is_a: NCBITaxon:8352 ! Pipidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:8457 name: Sauropsida namespace: ncbi_taxonomy synonym: "sauropsids" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:32524 ! Amniota property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:8459 name: Testudines namespace: ncbi_taxonomy synonym: "anapsid reptiles" EXACT common_name [] synonym: "Anapsida" RELATED synonym [] synonym: "reptiles" RELATED in_part [] synonym: "Reptilia" RELATED in_part [] synonym: "turtles" EXACT genbank_common_name [] synonym: "turtles" RELATED blast_name [] xref: GC_ID:1 xref: PMID:22839753 xref: PMID:25450099 is_a: NCBITaxon:2841271 ! Testudinata property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8492 name: Archosauria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1329799 ! Archelosauria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:8504 name: Lepidosauria namespace: ncbi_taxonomy synonym: "lepidosaurs" EXACT genbank_common_name [] synonym: "lizards & snakes" RELATED blast_name [] synonym: "reptiles" RELATED in_part [] synonym: "Reptilia" RELATED in_part [] xref: GC_ID:1 xref: PMID:22982760 is_a: NCBITaxon:32561 ! Sauria property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:8505 name: Sphenodontia namespace: ncbi_taxonomy synonym: "beaked reptiles" EXACT genbank_common_name [] synonym: "Rhynchocephalia" RELATED synonym [] synonym: "rhynchocephalians" EXACT common_name [] synonym: "Rhynchosauria" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:8504 ! Lepidosauria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8506 name: Sphenodontidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8505 ! Sphenodontia property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:8507 name: Sphenodon namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8506 ! Sphenodontidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:8509 name: Squamata namespace: ncbi_taxonomy synonym: "squamates" EXACT genbank_common_name [] xref: GC_ID:1 xref: PMID:16286089 xref: PMID:22982760 xref: PMID:23627680 is_a: NCBITaxon:8504 ! Lepidosauria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:85512 name: Dicondylia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:50557 ! Insecta property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:8570 name: Serpentes namespace: ncbi_taxonomy synonym: "Ophidia" RELATED synonym [] synonym: "snakes" EXACT genbank_common_name [] synonym: "snakes" RELATED blast_name [] xref: GC_ID:1 xref: PMID:19281946 is_a: NCBITaxon:1329911 ! Toxicofera property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:862507 name: Mus namespace: ncbi_taxonomy synonym: "Mus" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:10088 ! Mus property_value: has_rank NCBITaxon:subgenus [Term] id: NCBITaxon:8782 name: Aves namespace: ncbi_taxonomy synonym: "avian" RELATED synonym [] synonym: "birds" EXACT genbank_common_name [] synonym: "birds" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:436492 ! Coelurosauria property_value: has_rank NCBITaxon:class [Term] id: NCBITaxon:8783 name: Palaeognathae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:8798 name: Struthioniformes namespace: ncbi_taxonomy synonym: "ostriches" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8783 ! Palaeognathae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8799 name: Struthionidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8798 ! Struthioniformes property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:8800 name: Struthio namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8799 ! Struthionidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:8801 name: Struthio camelus namespace: ncbi_taxonomy synonym: "African ostrich" EXACT genbank_common_name [] synonym: "ostrich" EXACT common_name [] synonym: "Struthio camelus domesticus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:8800 ! Struthio property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:8825 name: Neognathae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:8782 ! Aves property_value: has_rank NCBITaxon:infraclass [Term] id: NCBITaxon:88770 name: Panarthropoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:1206794 ! Ecdysozoa property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:8929 name: Columbiformes namespace: ncbi_taxonomy synonym: "pigeons and others" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8825 ! Neognathae property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:8930 name: Columbidae namespace: ncbi_taxonomy synonym: "pigeons" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:8929 ! Columbiformes property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:89593 name: Craniata namespace: ncbi_taxonomy synonym: "Craniata" EXACT scientific_name [] xref: GC_ID:1 is_a: NCBITaxon:7711 ! Chordata property_value: has_rank NCBITaxon:subphylum [Term] id: NCBITaxon:91561 name: Artiodactyla namespace: ncbi_taxonomy synonym: "Cetartiodactyla" RELATED synonym [] synonym: "even-toed ungulates" RELATED blast_name [] synonym: "whales, hippos, ruminants, pigs, camels etc." EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:314145 ! Laurasiatheria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9254 name: Prototheria namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:40674 ! Mammalia property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:9255 name: Monotremata namespace: ncbi_taxonomy synonym: "egg-laying mammals" EXACT genbank_common_name [] synonym: "monotremes" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:9254 ! Prototheria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9256 name: Ornithorhynchidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9255 ! Monotremata property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9257 name: Ornithorhynchus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9256 ! Ornithorhynchidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9259 name: Tachyglossidae namespace: ncbi_taxonomy synonym: "echidnas" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9255 ! Monotremata property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9347 name: Eutheria namespace: ncbi_taxonomy synonym: "eutherian mammals" EXACT common_name [] synonym: "placental mammals" EXACT common_name [] synonym: "Placentalia" RELATED synonym [] synonym: "placentals" EXACT genbank_common_name [] synonym: "placentals" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:32525 ! Theria property_value: has_rank NCBITaxon:clade [Term] id: NCBITaxon:9348 name: Xenarthra namespace: ncbi_taxonomy synonym: "armadillos and others" EXACT genbank_common_name [] synonym: "Edentata" RELATED in_part [] xref: GC_ID:1 xref: PMID:11214319 is_a: NCBITaxon:9347 ! Eutheria property_value: has_rank NCBITaxon:superorder [Term] id: NCBITaxon:9359 name: Dasypodidae namespace: ncbi_taxonomy synonym: "armadillo" EXACT common_name [] synonym: "armadillos" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:948951 ! Cingulata property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9443 name: Primates namespace: ncbi_taxonomy synonym: "Primata" RELATED synonym [] synonym: "primate" EXACT equivalent_name [] synonym: "primates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314146 ! Euarchontoglires property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:948951 name: Cingulata namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9348 ! Xenarthra property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9526 name: Catarrhini namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:314293 ! Simiiformes property_value: has_rank NCBITaxon:parvorder [Term] id: NCBITaxon:9596 name: Pan namespace: ncbi_taxonomy alt_id: NCBITaxon:317028 alt_id: NCBITaxon:445518 synonym: "chimpanzees" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:207598 ! Homininae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9604 name: Hominidae namespace: ncbi_taxonomy synonym: "great apes" EXACT genbank_common_name [] synonym: "Pongidae" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:314295 ! Hominoidea property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9605 name: Homo namespace: ncbi_taxonomy synonym: "humans" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:207598 ! Homininae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9606 name: Homo sapiens namespace: ncbi_taxonomy synonym: "human" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9605 ! Homo property_value: has_rank NCBITaxon:species [Term] id: NCBITaxon:9608 name: Canidae namespace: ncbi_taxonomy synonym: "dog, coyote, wolf, fox" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379584 ! Caniformia property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9611 name: Canis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9608 ! Canidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9632 name: Ursidae namespace: ncbi_taxonomy synonym: "bears" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379584 ! Caniformia property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9639 name: Ursus namespace: ncbi_taxonomy alt_id: NCBITaxon:29068 xref: GC_ID:1 is_a: NCBITaxon:9632 ! Ursidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9681 name: Felidae namespace: ncbi_taxonomy synonym: "cat family" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379583 ! Feliformia property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9682 name: Felis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:338152 ! Felinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9709 name: Phocidae namespace: ncbi_taxonomy synonym: "crawling seals" EXACT common_name [] synonym: "earless seals" EXACT common_name [] synonym: "seal" EXACT common_name [] synonym: "seals" EXACT common_name [] synonym: "true seals" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:379584 ! Caniformia property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9721 name: Cetacea namespace: ncbi_taxonomy synonym: "cetaceans" EXACT common_name [] synonym: "whale" EXACT common_name [] synonym: "whales" EXACT genbank_common_name [] synonym: "whales & dolphins" RELATED blast_name [] synonym: "whales, dolphins, and porpoises" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:2653789 ! Whippomorpha property_value: has_rank NCBITaxon:infraorder [Term] id: NCBITaxon:9761 name: Mysticeti namespace: ncbi_taxonomy synonym: "baleen whales" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9721 ! Cetacea property_value: has_rank NCBITaxon:parvorder [Term] id: NCBITaxon:9787 name: Perissodactyla namespace: ncbi_taxonomy synonym: "odd-toed ungulates" EXACT genbank_common_name [] synonym: "odd-toed ungulates" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314145 ! Laurasiatheria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9788 name: Equidae namespace: ncbi_taxonomy synonym: "horses" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9787 ! Perissodactyla property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9789 name: Equus namespace: ncbi_taxonomy alt_id: NCBITaxon:1225530 alt_id: NCBITaxon:35506 alt_id: NCBITaxon:35507 alt_id: NCBITaxon:35508 alt_id: NCBITaxon:35509 alt_id: NCBITaxon:35510 alt_id: NCBITaxon:475184 synonym: "Amerhippus" RELATED synonym [] synonym: "Asinus" RELATED synonym [] synonym: "Dolichohippus" RELATED synonym [] synonym: "Equus subg. Amerhippus" RELATED synonym [] synonym: "Equus subg. Asinus" RELATED synonym [] synonym: "Equus subg. Dolichohippus" RELATED synonym [] synonym: "Equus subg. Equus" RELATED synonym [] synonym: "Equus subg. Hemionus" RELATED synonym [] synonym: "Equus subg. Hippotigris" RELATED synonym [] synonym: "Equus subgen. Sussemionus" RELATED synonym [] synonym: "Hemionus" RELATED synonym [] synonym: "Hippotigris" RELATED synonym [] synonym: "Sussemionus" RELATED synonym [] xref: GC_ID:1 is_a: NCBITaxon:9788 ! Equidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9815 name: Tubulidentata namespace: ncbi_taxonomy synonym: "aardvarks" EXACT genbank_common_name [] synonym: "Edentata" RELATED in_part [] xref: GC_ID:1 is_a: NCBITaxon:311790 ! Afrotheria property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9816 name: Orycteropodidae namespace: ncbi_taxonomy synonym: "aardvark" EXACT genbank_common_name [] synonym: "aardvarks" EXACT common_name [] xref: GC_ID:1 is_a: NCBITaxon:9815 ! Tubulidentata property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9821 name: Suidae namespace: ncbi_taxonomy alt_id: NCBITaxon:39423 synonym: "boars" EXACT common_name [] synonym: "pigs" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:35497 ! Suina property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9822 name: Sus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9821 ! Suidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9834 name: Tylopoda namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:9835 name: Camelidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9834 ! Tylopoda property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9836 name: Camelus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9835 ! Camelidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9845 name: Ruminantia namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:91561 ! Artiodactyla property_value: has_rank NCBITaxon:suborder [Term] id: NCBITaxon:9850 name: Cervidae namespace: ncbi_taxonomy synonym: "deer" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:35500 ! Pecora property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9859 name: Cervus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:34878 ! Cervinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9895 name: Bovidae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:35500 ! Pecora property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9903 name: Bos namespace: ncbi_taxonomy synonym: "oxen, cattle" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:27592 ! Bovinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9922 name: Capra namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9963 ! Caprinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9935 name: Ovis namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9963 ! Caprinae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9963 name: Caprinae namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9895 ! Bovidae property_value: has_rank NCBITaxon:subfamily [Term] id: NCBITaxon:9975 name: Lagomorpha namespace: ncbi_taxonomy synonym: "rabbits & hares" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314147 ! Glires property_value: has_rank NCBITaxon:order [Term] id: NCBITaxon:9979 name: Leporidae namespace: ncbi_taxonomy synonym: "rabbits and hares" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9975 ! Lagomorpha property_value: has_rank NCBITaxon:family [Term] id: NCBITaxon:9980 name: Lepus namespace: ncbi_taxonomy synonym: "hares" EXACT genbank_common_name [] xref: GC_ID:1 is_a: NCBITaxon:9979 ! Leporidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9984 name: Oryctolagus namespace: ncbi_taxonomy xref: GC_ID:1 is_a: NCBITaxon:9979 ! Leporidae property_value: has_rank NCBITaxon:genus [Term] id: NCBITaxon:9989 name: Rodentia namespace: ncbi_taxonomy synonym: "rodent" EXACT genbank_common_name [] synonym: "rodents" RELATED blast_name [] xref: GC_ID:1 is_a: NCBITaxon:314147 ! Glires property_value: has_rank NCBITaxon:order [Term] id: OBA:0002017 name: gonad size def: "The size of a gonad." [AUTO:patterns/patterns/entity_attribute] synonym: "size of gonad" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000991 ! gonad relationship: characteristic_of UBERON:0000991 ! gonad [Term] id: OBA:0002161 name: diaphysis length def: "The length of a diaphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "length of diaphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002587 ! diaphysis size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004769 ! diaphysis [Term] id: OBA:0002162 name: ilium size def: "The size of a ilium." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ilium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: OBA:VT0005354 ! ilium morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001273 ! ilium relationship: characteristic_of UBERON:0001273 ! ilium [Term] id: OBA:0002188 name: manus size def: "The size of a manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000550 ! forelimb morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002398 ! manus relationship: characteristic_of UBERON:0002398 ! manus [Term] id: OBA:0002195 name: metacarpal bone size def: "The size of a metacarpal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metacarpal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003763 ! metacarpal bone morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002374 ! metacarpal bone relationship: characteristic_of UBERON:0002374 ! metacarpal bone [Term] id: OBA:0002225 name: diastema between upper central incisors length def: "The length of a diastema between upper central incisors." [AUTO:patterns/patterns/entity_attribute] synonym: "length of diastema between upper central incisors" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: FOVT:0001346 ! diastema between central incisors length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0035116 ! diastema between upper central incisors relationship: characteristic_of UBERON:0035116 ! diastema between upper central incisors [Term] id: OBA:0002251 name: metatarsal bone size def: "The size of a metatarsal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metatarsal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0003072 ! metatarsus morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001448 ! metatarsal bone relationship: characteristic_of UBERON:0001448 ! metatarsal bone [Term] id: OBA:0002265 name: calcaneus morphology def: "The morphology of a calcaneus." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of calcaneus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001450 ! calcaneus relationship: characteristic_of_part_of UBERON:0001450 ! calcaneus [Term] id: OBA:0002267 name: distal phalanx of pes length def: "The length of a distal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003079 ! distal phalanx of pes size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003867 ! distal phalanx of pes [Term] id: OBA:0002346 name: foramen magnum size def: "The size of a foramen magnum." [AUTO:patterns/patterns/entity_attribute] synonym: "size of foramen magnum" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0005278 ! foramen magnum morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003687 ! foramen magnum relationship: characteristic_of UBERON:0003687 ! foramen magnum [Term] id: OBA:0002374 name: radius bone size def: "The size of a radius bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of radius bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000552 ! radius morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001423 ! radius bone relationship: characteristic_of UBERON:0001423 ! radius bone [Term] id: OBA:0002379 name: ulna size def: "The size of a ulna." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ulna" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005108 ! ulna morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001424 ! ulna relationship: characteristic_of UBERON:0001424 ! ulna [Term] id: OBA:0002384 name: fibula size def: "The size of a fibula." [AUTO:patterns/patterns/entity_attribute] synonym: "size of fibula" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0002187 ! fibula morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001446 ! fibula relationship: characteristic_of UBERON:0001446 ! fibula [Term] id: OBA:0002386 name: patella size def: "The size of a patella." [AUTO:patterns/patterns/entity_attribute] synonym: "size of patella" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005353 ! patella morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002446 ! patella relationship: characteristic_of UBERON:0002446 ! patella [Term] id: OBA:0002389 name: proximal epiphysis of femur size def: "The size of a proximal epiphysis of femur." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal epiphysis of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000559 ! femur morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004412 ! proximal epiphysis of femur relationship: characteristic_of UBERON:0004412 ! proximal epiphysis of femur [Term] id: OBA:0002391 name: ischium size def: "The size of a ischium." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ischium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002413 ! pelvic girdle bone/zone size is_a: OBA:VT0010087 ! ischium morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001274 ! ischium relationship: characteristic_of UBERON:0001274 ! ischium [Term] id: OBA:0002395 name: pubic symphysis size def: "The size of a pubic symphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pubic symphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0004782 ! pubic symphysis morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003699 ! pubic symphysis relationship: characteristic_of UBERON:0003699 ! pubic symphysis [Term] id: OBA:0002412 name: acetabular part of hip bone size def: "The size of a acetabular part of hip bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of acetabular part of hip bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000334 ! acetabular part of hip bone quality is_a: OBA:VT0005354 ! ilium morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001269 ! acetabular part of hip bone relationship: characteristic_of UBERON:0001269 ! acetabular part of hip bone [Term] id: OBA:0002413 name: pelvic girdle bone/zone size def: "The size of a pelvic girdle bone/zone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pelvic girdle bone/zone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003356 ! pelvic girdle bone/zone morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0007830 ! pelvic girdle bone/zone relationship: characteristic_of UBERON:0007830 ! pelvic girdle bone/zone [Term] id: OBA:0002452 name: middle phalanx of pes length def: "The length of a middle phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003083 ! middle phalanx of pes size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003866 ! middle phalanx of pes [Term] id: OBA:0002474 name: humerus diaphysis size def: "The size of a humerus diaphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of humerus diaphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002587 ! diaphysis size is_a: OBA:VT0005296 ! humerus morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004652 ! humerus diaphysis relationship: characteristic_of UBERON:0004652 ! humerus diaphysis [Term] id: OBA:0002514 name: distal phalanx of manual digit 3 length def: "The length of a distal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002939 ! distal phalanx of manual digit 3 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004312 ! distal phalanx of manual digit 3 [Term] id: OBA:0002517 name: middle phalanx of manual digit 5 length def: "The length of a middle phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002895 ! middle phalanx of manual digit 5 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004323 ! middle phalanx of manual digit 5 [Term] id: OBA:0002519 name: distal phalanx of manual digit 5 length def: "The length of a distal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002909 ! distal phalanx of manual digit 5 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004314 ! distal phalanx of manual digit 5 [Term] id: OBA:0002546 name: facial skeleton size def: "The size of a facial skeleton." [AUTO:patterns/patterns/entity_attribute] synonym: "size of facial skeleton" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "viscerocranium size" RELATED [] is_a: OBA:VT0005274 ! facial skeleton morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0011156 ! facial skeleton relationship: characteristic_of UBERON:0011156 ! facial skeleton relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0002556 name: fused sacrum size def: "The size of a fused sacrum." [AUTO:patterns/patterns/entity_attribute] synonym: "size of fused sacrum" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0004993 ! fused sacrum morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003690 ! fused sacrum relationship: characteristic_of UBERON:0003690 ! fused sacrum [Term] id: OBA:0002565 name: metatarsal bone of digit 3 length def: "The length of a metatarsal bone of digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 3 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 3 maximal length (M1)" EXACT [] synonym: "metatarsal III greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "third metatarsal maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000413 ! metatarsal bone of digit 3 quality intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: characteristic_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0002567 name: metatarsal bone of digit 4 length def: "The length of a metatarsal bone of digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 4 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 4 maximal length (M1)" EXACT [] synonym: "metatarsal IV greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metatarsal IV maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000611 ! metatarsal bone of digit 4 quality intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: characteristic_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0002569 name: metatarsal bone of digit 5 length def: "The length of a metatarsal bone of digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 5 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 5 maximal length (M1)" EXACT [] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000254 ! metatarsal bone of digit 5 quality intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003654 ! metatarsal bone of digit 5 relationship: characteristic_of UBERON:0003654 ! metatarsal bone of digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0002587 name: diaphysis size def: "The size of a diaphysis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of diaphysis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0004214 ! long bone diaphysis morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004769 ! diaphysis relationship: characteristic_of UBERON:0004769 ! diaphysis [Term] id: OBA:0002588 name: phalanx of pes length def: "The length of a phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:VT0002543 ! phalanx length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001449 ! phalanx of pes [Term] id: OBA:0002620 name: chest size def: "The size of a chest." [AUTO:patterns/patterns/entity_attribute] synonym: "size of chest" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003917 ! chest morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001443 relationship: characteristic_of UBERON:0001443 [Term] id: OBA:0002661 name: middle phalanx of manus length def: "The length of a middle phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002683 ! phalanx of manus length is_a: OBA:0003009 ! middle phalanx of manus size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003864 ! middle phalanx of manus [Term] id: OBA:0002674 name: phalanx size def: "The size of a phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005306 ! phalanx morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003221 ! phalanx relationship: characteristic_of UBERON:0003221 ! phalanx [Term] id: OBA:0002676 name: metacarpal bone of digit 2 length def: "The length of a metacarpal bone of digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 2 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 2 maximal length (M1)" EXACT [] synonym: "metacarpal II greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metacarpal II length" EXACT [] synonym: "metacarpal II maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003646 ! metacarpal bone of digit 2 relationship: characteristic_of UBERON:0003646 ! metacarpal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0002681 name: proximal phalanx of manus length def: "The length of a proximal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002683 ! phalanx of manus length is_a: OBA:0003012 ! proximal phalanx of manus size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002234 ! proximal phalanx of manus [Term] id: OBA:0002683 name: phalanx of manus length def: "The length of a phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:VT0002543 ! phalanx length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001436 ! phalanx of manus [Term] id: OBA:0002703 name: primary dentition size def: "The size of a primary dentition." [AUTO:patterns/patterns/entity_attribute] synonym: "size of primary dentition" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0007116 ! primary dentition relationship: characteristic_of UBERON:0007116 ! primary dentition [Term] id: OBA:0002710 name: premolar tooth size def: "The size of a premolar tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "size of premolar tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003215 ! premolar tooth morphology is_a: OBA:1000112 ! tooth size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0007120 ! premolar tooth relationship: characteristic_of UBERON:0007120 ! premolar tooth [Term] id: OBA:0002716 name: distal epiphysis of radius size def: "The size of a distal epiphysis of radius." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal epiphysis of radius" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000600 ! distal epiphysis of radius quality is_a: OBA:VT0000552 ! radius morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004407 ! distal epiphysis of radius relationship: characteristic_of UBERON:0004407 ! distal epiphysis of radius [Term] id: OBA:0002726 name: distal epiphysis of femur size def: "The size of a distal epiphysis of femur." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal epiphysis of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000180 ! distal epiphysis of femur quality is_a: OBA:VT0000559 ! femur morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004406 ! distal epiphysis of femur relationship: characteristic_of UBERON:0004406 ! distal epiphysis of femur [Term] id: OBA:0002741 name: glenoid fossa size def: "The size of a glenoid fossa." [AUTO:patterns/patterns/entity_attribute] synonym: "size of glenoid fossa" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000409 ! glenoid fossa quality is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0006657 ! glenoid fossa relationship: characteristic_of UBERON:0006657 ! glenoid fossa [Term] id: OBA:0002823 name: vertebra size def: "The size of a vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "size of vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000137 ! vertebra morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002412 ! vertebra relationship: characteristic_of UBERON:0002412 ! vertebra [Term] id: OBA:0002828 name: lumbar vertebra 5 size def: "The size of a lumbar vertebra 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of lumbar vertebra 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010518 ! lumbar vertebra size trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004621 ! lumbar vertebra 5 relationship: characteristic_of UBERON:0004621 ! lumbar vertebra 5 [Term] id: OBA:0002830 name: cervical vertebra size def: "The size of a cervical vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "size of cervical vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002823 ! vertebra size is_a: OBA:0003760 ! cervical vertebra morphology intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002413 ! cervical vertebra relationship: characteristic_of UBERON:0002413 ! cervical vertebra [Term] id: OBA:0002845 name: external ear morphology def: "The morphology of a external ear." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of external ear" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0002102 ! ear morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001691 ! external ear relationship: characteristic_of_part_of UBERON:0001691 ! external ear [Term] id: OBA:0002863 name: lesser trochanter size def: "The size of a lesser trochanter." [AUTO:patterns/patterns/entity_attribute] synonym: "size of lesser trochanter" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000559 ! femur morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002504 ! lesser trochanter relationship: characteristic_of UBERON:0002504 ! lesser trochanter [Term] id: OBA:0002864 name: head of femur size def: "The size of a head of femur." [AUTO:patterns/patterns/entity_attribute] synonym: "size of head of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000559 ! femur morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0006767 ! head of femur relationship: characteristic_of UBERON:0006767 ! head of femur [Term] id: OBA:0002895 name: middle phalanx of manual digit 5 size def: "The size of a middle phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002931 ! manual digit 5 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000555 ! middle phalanx of manual digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004323 ! middle phalanx of manual digit 5 relationship: characteristic_of UBERON:0004323 ! middle phalanx of manual digit 5 [Term] id: OBA:0002903 name: proximal phalanx of manual digit 5 length def: "The length of a proximal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002904 ! proximal phalanx of manual digit 5 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004331 ! proximal phalanx of manual digit 5 [Term] id: OBA:0002904 name: proximal phalanx of manual digit 5 size def: "The size of a proximal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002931 ! manual digit 5 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000150 ! proximal phalanx of manual digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004331 ! proximal phalanx of manual digit 5 relationship: characteristic_of UBERON:0004331 ! proximal phalanx of manual digit 5 [Term] id: OBA:0002909 name: distal phalanx of manual digit 5 size def: "The size of a distal phalanx of manual digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002931 ! manual digit 5 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000271 ! distal phalanx of manual digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004314 ! distal phalanx of manual digit 5 relationship: characteristic_of UBERON:0004314 ! distal phalanx of manual digit 5 [Term] id: OBA:0002918 name: distal phalanx of manual digit 4 length def: "The length of a distal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002919 ! distal phalanx of manual digit 4 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004313 ! distal phalanx of manual digit 4 [Term] id: OBA:0002919 name: distal phalanx of manual digit 4 size def: "The size of a distal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002936 ! manual digit 4 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000291 ! distal phalanx of manual digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004313 ! distal phalanx of manual digit 4 relationship: characteristic_of UBERON:0004313 ! distal phalanx of manual digit 4 [Term] id: OBA:0002920 name: middle phalanx of manual digit 4 size def: "The size of a middle phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002936 ! manual digit 4 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000208 ! middle phalanx of manual digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004322 ! middle phalanx of manual digit 4 relationship: characteristic_of UBERON:0004322 ! middle phalanx of manual digit 4 [Term] id: OBA:0002921 name: middle phalanx of manual digit 4 length def: "The length of a middle phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002920 ! middle phalanx of manual digit 4 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004322 ! middle phalanx of manual digit 4 [Term] id: OBA:0002923 name: proximal phalanx of manual digit 4 length def: "The length of a proximal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002927 ! proximal phalanx of manual digit 4 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004330 ! proximal phalanx of manual digit 4 [Term] id: OBA:0002927 name: proximal phalanx of manual digit 4 size def: "The size of a proximal phalanx of manual digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002936 ! manual digit 4 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000204 ! proximal phalanx of manual digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004330 ! proximal phalanx of manual digit 4 relationship: characteristic_of UBERON:0004330 ! proximal phalanx of manual digit 4 [Term] id: OBA:0002931 name: manual digit 5 phalanx size def: "The size of a manual digit 5 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 5 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003639 ! manual digit 5 phalanx relationship: characteristic_of UBERON:0003639 ! manual digit 5 phalanx [Term] id: OBA:0002936 name: manual digit 4 phalanx size def: "The size of a manual digit 4 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 4 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000158 ! manual digit 4 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003638 ! manual digit 4 phalanx relationship: characteristic_of UBERON:0003638 ! manual digit 4 phalanx [Term] id: OBA:0002939 name: distal phalanx of manual digit 3 size def: "The size of a distal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002948 ! manual digit 3 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000210 ! distal phalanx of manual digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004312 ! distal phalanx of manual digit 3 relationship: characteristic_of UBERON:0004312 ! distal phalanx of manual digit 3 [Term] id: OBA:0002943 name: middle phalanx of manual digit 3 size def: "The size of a middle phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002948 ! manual digit 3 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000526 ! middle phalanx of manual digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004321 ! middle phalanx of manual digit 3 relationship: characteristic_of UBERON:0004321 ! middle phalanx of manual digit 3 [Term] id: OBA:0002947 name: middle phalanx of manual digit 3 length def: "The length of a middle phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002943 ! middle phalanx of manual digit 3 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004321 ! middle phalanx of manual digit 3 [Term] id: OBA:0002948 name: manual digit 3 phalanx size def: "The size of a manual digit 3 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 3 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003637 ! manual digit 3 phalanx relationship: characteristic_of UBERON:0003637 ! manual digit 3 phalanx [Term] id: OBA:0002952 name: proximal phalanx of manual digit 3 size def: "The size of a proximal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002948 ! manual digit 3 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000178 ! proximal phalanx of manual digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004329 ! proximal phalanx of manual digit 3 relationship: characteristic_of UBERON:0004329 ! proximal phalanx of manual digit 3 [Term] id: OBA:0002956 name: proximal phalanx of manual digit 3 length def: "The length of a proximal phalanx of manual digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002952 ! proximal phalanx of manual digit 3 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004329 ! proximal phalanx of manual digit 3 [Term] id: OBA:0002962 name: manual digit 2 phalanx size def: "The size of a manual digit 2 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of manual digit 2 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003636 ! manual digit 2 phalanx relationship: characteristic_of UBERON:0003636 ! manual digit 2 phalanx [Term] id: OBA:0002966 name: distal phalanx of manual digit 2 size def: "The size of a distal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002962 ! manual digit 2 phalanx size is_a: OBA:0003006 ! distal phalanx of manus size is_a: OBA:1000325 ! distal phalanx of manual digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004311 ! distal phalanx of manual digit 2 relationship: characteristic_of UBERON:0004311 ! distal phalanx of manual digit 2 [Term] id: OBA:0002970 name: distal phalanx of manual digit 2 length def: "The length of a distal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002966 ! distal phalanx of manual digit 2 size is_a: OBA:0003016 ! distal phalanx of manus length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004311 ! distal phalanx of manual digit 2 [Term] id: OBA:0002971 name: middle phalanx of manual digit 2 size def: "The size of a middle phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002962 ! manual digit 2 phalanx size is_a: OBA:0003009 ! middle phalanx of manus size is_a: OBA:1000510 ! middle phalanx of manual digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004320 ! middle phalanx of manual digit 2 relationship: characteristic_of UBERON:0004320 ! middle phalanx of manual digit 2 [Term] id: OBA:0002975 name: middle phalanx of manual digit 2 length def: "The length of a middle phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of middle phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002661 ! middle phalanx of manus length is_a: OBA:0002971 ! middle phalanx of manual digit 2 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004320 ! middle phalanx of manual digit 2 [Term] id: OBA:0002976 name: proximal phalanx of manual digit 2 size def: "The size of a proximal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002962 ! manual digit 2 phalanx size is_a: OBA:0003012 ! proximal phalanx of manus size is_a: OBA:1000228 ! proximal phalanx of manual digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004328 ! proximal phalanx of manual digit 2 relationship: characteristic_of UBERON:0004328 ! proximal phalanx of manual digit 2 [Term] id: OBA:0002980 name: proximal phalanx of manual digit 2 length def: "The length of a proximal phalanx of manual digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002976 ! proximal phalanx of manual digit 2 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004328 ! proximal phalanx of manual digit 2 [Term] id: OBA:0002986 name: proximal phalanx of manual digit 1 size def: "The size of a proximal phalanx of manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003012 ! proximal phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004338 ! proximal phalanx of manual digit 1 relationship: characteristic_of UBERON:0004338 ! proximal phalanx of manual digit 1 [Term] id: OBA:0002989 name: proximal phalanx of manual digit 1 length def: "The length of a proximal phalanx of manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002681 ! proximal phalanx of manus length is_a: OBA:0002986 ! proximal phalanx of manual digit 1 size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0004338 ! proximal phalanx of manual digit 1 [Term] id: OBA:0002990 name: distal phalanx of manual digit 1 size def: "The size of a distal phalanx of manual digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manual digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003006 ! distal phalanx of manus size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004337 ! distal phalanx of manual digit 1 relationship: characteristic_of UBERON:0004337 ! distal phalanx of manual digit 1 [Term] id: OBA:0002999 name: phalanx of manus size def: "The size of a phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002674 ! phalanx size is_a: OBA:1000632 ! phalanx of manus quality is_a: OBA:VT0000550 ! forelimb morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001436 ! phalanx of manus relationship: characteristic_of UBERON:0001436 ! phalanx of manus [Term] id: OBA:0003006 name: distal phalanx of manus size def: "The size of a distal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003865 ! distal phalanx of manus relationship: characteristic_of UBERON:0003865 ! distal phalanx of manus [Term] id: OBA:0003009 name: middle phalanx of manus size def: "The size of a middle phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000382 ! middle phalanx of manus quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003864 ! middle phalanx of manus relationship: characteristic_of UBERON:0003864 ! middle phalanx of manus [Term] id: OBA:0003012 name: proximal phalanx of manus size def: "The size of a proximal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002999 ! phalanx of manus size is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002234 ! proximal phalanx of manus relationship: characteristic_of UBERON:0002234 ! proximal phalanx of manus [Term] id: OBA:0003016 name: distal phalanx of manus length def: "The length of a distal phalanx of manus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of distal phalanx of manus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002683 ! phalanx of manus length is_a: OBA:0003006 ! distal phalanx of manus size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003865 ! distal phalanx of manus [Term] id: OBA:0003040 name: metacarpal bone of digit 1 size def: "The size of a metacarpal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metacarpal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002195 ! metacarpal bone size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003645 ! metacarpal bone of digit 1 relationship: characteristic_of UBERON:0003645 ! metacarpal bone of digit 1 [Term] id: OBA:0003043 name: metacarpal bone of digit 1 length def: "The length of a metacarpal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 1 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 1 maximal length (M1)" EXACT [] synonym: "metacarpal I length" EXACT [] is_a: OBA:0003040 ! metacarpal bone of digit 1 size is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003645 ! metacarpal bone of digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003044 name: metacarpal bone of digit 3 length def: "The length of a metacarpal bone of digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpa III greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metacarpal bone of digit 3 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 3 maximal length (M1)" EXACT [] synonym: "metacarpal III length" EXACT [] synonym: "third metacarpal maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003045 name: metacarpal bone of digit 4 length def: "The length of a metacarpal bone of digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 4 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 4 maximal length (M1)" EXACT [] synonym: "metacarpal IV greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metacarpal IV length" EXACT [] synonym: "metacarpal IV maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003648 ! metacarpal bone of digit 4 relationship: characteristic_of UBERON:0003648 ! metacarpal bone of digit 4 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003046 name: metacarpal bone of digit 5 length def: "The length of a metacarpal bone of digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone of digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metacarpal bone of digit 5 greatest length (GL)" EXACT [] synonym: "metacarpal bone of digit 5 maximal length (M1)" EXACT [] synonym: "metacarpal V greatest length" RELATED [ISBN:9780873659505] synonym: "metacarpal V length" EXACT [] is_a: OBA:0003047 ! metacarpal bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003649 ! metacarpal bone of digit 5 relationship: characteristic_of UBERON:0003649 ! metacarpal bone of digit 5 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003047 name: metacarpal bone length def: "The length of a metacarpal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metacarpal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: FOVT:0001141 ! metapodial bone length is_a: OBA:0002195 ! metacarpal bone size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002374 ! metacarpal bone [Term] id: OBA:0003049 name: pedal digit 1 phalanx size def: "The size of a pedal digit 1 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 1 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000161 ! pedal digit 1 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003640 ! pedal digit 1 phalanx relationship: characteristic_of UBERON:0003640 ! pedal digit 1 phalanx [Term] id: OBA:0003053 name: metatarsal bone of digit 1 size def: "The size of a metatarsal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of metatarsal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002251 ! metatarsal bone size is_a: OBA:1000597 ! metatarsal bone of digit 1 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003650 ! metatarsal bone of digit 1 relationship: characteristic_of UBERON:0003650 ! metatarsal bone of digit 1 [Term] id: OBA:0003057 name: distal phalanx of pedal digit 1 size def: "The size of a distal phalanx of pedal digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003049 ! pedal digit 1 phalanx size is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:1000571 ! distal phalanx of pedal digit 1 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004315 ! distal phalanx of pedal digit 1 relationship: characteristic_of UBERON:0004315 ! distal phalanx of pedal digit 1 [Term] id: OBA:0003061 name: proximal phalanx of pedal digit 1 size def: "The size of a proximal phalanx of pedal digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003049 ! pedal digit 1 phalanx size is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:1000461 ! proximal phalanx of pedal digit 1 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004332 ! proximal phalanx of pedal digit 1 relationship: characteristic_of UBERON:0004332 ! proximal phalanx of pedal digit 1 [Term] id: OBA:0003066 name: metatarsal bone of digit 1 length def: "The length of a metatarsal bone of digit 1." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 1" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 1 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 1 maximal length (M1)" EXACT [] is_a: OBA:0003053 ! metatarsal bone of digit 1 size is_a: OBA:0004033 ! metatarsal bone length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003650 ! metatarsal bone of digit 1 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003067 name: pedal digit 1 phalanx length def: "The length of a pedal digit 1 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "length of pedal digit 1 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003049 ! pedal digit 1 phalanx size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003640 ! pedal digit 1 phalanx [Term] id: OBA:0003075 name: phalanx of pes size def: "The size of a phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002674 ! phalanx size is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001449 ! phalanx of pes relationship: characteristic_of UBERON:0001449 ! phalanx of pes [Term] id: OBA:0003079 name: distal phalanx of pes size def: "The size of a distal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003867 ! distal phalanx of pes relationship: characteristic_of UBERON:0003867 ! distal phalanx of pes [Term] id: OBA:0003083 name: middle phalanx of pes size def: "The size of a middle phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003866 ! middle phalanx of pes relationship: characteristic_of UBERON:0003866 ! middle phalanx of pes [Term] id: OBA:0003087 name: proximal phalanx of pes size def: "The size of a proximal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000212 ! proximal phalanx of pes quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003868 ! proximal phalanx of pes relationship: characteristic_of UBERON:0003868 ! proximal phalanx of pes [Term] id: OBA:0003100 name: hard palate size def: "The size of a hard palate." [AUTO:patterns/patterns/entity_attribute] synonym: "size of hard palate" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0003756 ! hard palate morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003216 ! hard palate relationship: characteristic_of UBERON:0003216 ! hard palate [Term] id: OBA:0003105 name: chest length def: "The length of a chest." [AUTO:patterns/patterns/entity_attribute] synonym: "length of chest" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002620 ! chest size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001443 [Term] id: OBA:0003111 name: pedal digit 2 phalanx size def: "The size of a pedal digit 2 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 2 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000353 ! pedal digit 2 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003641 ! pedal digit 2 phalanx relationship: characteristic_of UBERON:0003641 ! pedal digit 2 phalanx [Term] id: OBA:0003115 name: pedal digit 3 phalanx size def: "The size of a pedal digit 3 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 3 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000378 ! pedal digit 3 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003642 ! pedal digit 3 phalanx relationship: characteristic_of UBERON:0003642 ! pedal digit 3 phalanx [Term] id: OBA:0003119 name: pedal digit 4 phalanx size def: "The size of a pedal digit 4 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 4 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000575 ! pedal digit 4 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003862 ! pedal digit 4 phalanx relationship: characteristic_of UBERON:0003862 ! pedal digit 4 phalanx [Term] id: OBA:0003123 name: pedal digit 5 phalanx size def: "The size of a pedal digit 5 phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pedal digit 5 phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003075 ! phalanx of pes size is_a: OBA:1000329 ! pedal digit 5 phalanx quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003863 ! pedal digit 5 phalanx relationship: characteristic_of UBERON:0003863 ! pedal digit 5 phalanx [Term] id: OBA:0003127 name: proximal phalanx of pedal digit 2 size def: "The size of a proximal phalanx of pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003111 ! pedal digit 2 phalanx size is_a: OBA:1000170 ! proximal phalanx of pedal digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004333 ! proximal phalanx of pedal digit 2 relationship: characteristic_of UBERON:0004333 ! proximal phalanx of pedal digit 2 [Term] id: OBA:0003131 name: middle phalanx of pedal digit 2 size def: "The size of a middle phalanx of pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003111 ! pedal digit 2 phalanx size is_a: OBA:1000389 ! middle phalanx of pedal digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004324 ! middle phalanx of pedal digit 2 relationship: characteristic_of UBERON:0004324 ! middle phalanx of pedal digit 2 [Term] id: OBA:0003135 name: distal phalanx of pedal digit 2 size def: "The size of a distal phalanx of pedal digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003111 ! pedal digit 2 phalanx size is_a: OBA:1000427 ! distal phalanx of pedal digit 2 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: characteristic_of UBERON:0004316 ! distal phalanx of pedal digit 2 [Term] id: OBA:0003215 name: premolar tooth morphology def: "The morphology of a premolar tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of premolar tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000593 ! premolar tooth quality is_a: OBA:VT0002100 ! tooth morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0007120 ! premolar tooth [Term] id: OBA:0003272 name: metatarsal bone of digit 2 length def: "The length of a metatarsal bone of digit 2." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone of digit 2" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "metatarsal bone of digit 2 greatest length (GL)" EXACT [] synonym: "metatarsal bone of digit 2 maximal length (M1)" EXACT [] synonym: "metatarsal II greatest length (GL)" RELATED [ISBN:9780873659505] synonym: "metatarsal II maximal length (M1)" RELATED [ISBN:9004086161\, 9789004086166] is_a: OBA:0004033 ! metatarsal bone length is_a: OBA:1000491 ! metatarsal bone of digit 2 quality intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003651 ! metatarsal bone of digit 2 relationship: characteristic_of UBERON:0003651 ! metatarsal bone of digit 2 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003281 name: proximal phalanx of pes length def: "The length of a proximal phalanx of pes." [AUTO:patterns/patterns/entity_attribute] synonym: "length of proximal phalanx of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002588 ! phalanx of pes length is_a: OBA:0003087 ! proximal phalanx of pes size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003868 ! proximal phalanx of pes [Term] id: OBA:0003298 name: proximal epiphysis of tibia size def: "The size of a proximal epiphysis of tibia." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal epiphysis of tibia" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000148 ! proximal epiphysis of tibia quality is_a: OBA:VT0000558 ! tibia morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0008772 ! proximal epiphysis of tibia relationship: characteristic_of UBERON:0008772 ! proximal epiphysis of tibia [Term] id: OBA:0003330 name: calcaneus size def: "The size of a calcaneus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of calcaneus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002265 ! calcaneus morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001450 ! calcaneus relationship: characteristic_of UBERON:0001450 ! calcaneus [Term] id: OBA:0003356 name: pelvic girdle bone/zone morphology def: "The morphology of a pelvic girdle bone/zone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of pelvic girdle bone/zone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0007830 ! pelvic girdle bone/zone relationship: characteristic_of_part_of UBERON:0007830 ! pelvic girdle bone/zone [Term] id: OBA:0003366 name: distal phalanx of pedal digit 3 size def: "The size of a distal phalanx of pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003115 ! pedal digit 3 phalanx size is_a: OBA:1000328 ! distal phalanx of pedal digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: characteristic_of UBERON:0004317 ! distal phalanx of pedal digit 3 [Term] id: OBA:0003367 name: distal phalanx of pedal digit 4 size def: "The size of a distal phalanx of pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003119 ! pedal digit 4 phalanx size is_a: OBA:1000468 ! distal phalanx of pedal digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: characteristic_of UBERON:0004318 ! distal phalanx of pedal digit 4 [Term] id: OBA:0003368 name: distal phalanx of pedal digit 5 size def: "The size of a distal phalanx of pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of distal phalanx of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003079 ! distal phalanx of pes size is_a: OBA:0003123 ! pedal digit 5 phalanx size is_a: OBA:1000283 ! distal phalanx of pedal digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004319 ! distal phalanx of pedal digit 5 relationship: characteristic_of UBERON:0004319 ! distal phalanx of pedal digit 5 [Term] id: OBA:0003369 name: middle phalanx of pedal digit 3 size def: "The size of a middle phalanx of pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003115 ! pedal digit 3 phalanx size is_a: OBA:1000419 ! middle phalanx of pedal digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004325 ! middle phalanx of pedal digit 3 relationship: characteristic_of UBERON:0004325 ! middle phalanx of pedal digit 3 [Term] id: OBA:0003370 name: middle phalanx of pedal digit 4 size def: "The size of a middle phalanx of pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003119 ! pedal digit 4 phalanx size is_a: OBA:1000299 ! middle phalanx of pedal digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004326 ! middle phalanx of pedal digit 4 relationship: characteristic_of UBERON:0004326 ! middle phalanx of pedal digit 4 [Term] id: OBA:0003371 name: middle phalanx of pedal digit 5 size def: "The size of a middle phalanx of pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of middle phalanx of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003083 ! middle phalanx of pes size is_a: OBA:0003123 ! pedal digit 5 phalanx size is_a: OBA:1000175 ! middle phalanx of pedal digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004327 ! middle phalanx of pedal digit 5 relationship: characteristic_of UBERON:0004327 ! middle phalanx of pedal digit 5 [Term] id: OBA:0003372 name: proximal phalanx of pedal digit 3 size def: "The size of a proximal phalanx of pedal digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003115 ! pedal digit 3 phalanx size is_a: OBA:1000422 ! proximal phalanx of pedal digit 3 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004334 ! proximal phalanx of pedal digit 3 relationship: characteristic_of UBERON:0004334 ! proximal phalanx of pedal digit 3 [Term] id: OBA:0003373 name: proximal phalanx of pedal digit 4 size def: "The size of a proximal phalanx of pedal digit 4." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 4" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003119 ! pedal digit 4 phalanx size is_a: OBA:1000215 ! proximal phalanx of pedal digit 4 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004335 ! proximal phalanx of pedal digit 4 relationship: characteristic_of UBERON:0004335 ! proximal phalanx of pedal digit 4 [Term] id: OBA:0003374 name: proximal phalanx of pedal digit 5 size def: "The size of a proximal phalanx of pedal digit 5." [AUTO:patterns/patterns/entity_attribute] synonym: "size of proximal phalanx of pedal digit 5" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0003087 ! proximal phalanx of pes size is_a: OBA:0003123 ! pedal digit 5 phalanx size is_a: OBA:1000240 ! proximal phalanx of pedal digit 5 quality intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004336 ! proximal phalanx of pedal digit 5 relationship: characteristic_of UBERON:0004336 ! proximal phalanx of pedal digit 5 [Term] id: OBA:0003407 name: ilium height def: "The height of a ilium." [AUTO:patterns/patterns/entity_attribute] synonym: "height of ilium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002162 ! ilium size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0001273 ! ilium [Term] id: OBA:0003426 name: external ear length def: "The length of a external ear." [AUTO:patterns/patterns/entity_attribute] synonym: "ear length" BROAD [] synonym: "length of external ear" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000017 ! outer ear size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001691 ! external ear relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:0003439 name: ear size def: "The size of a ear." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ear" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0002102 ! ear morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001690 ! ear relationship: characteristic_of UBERON:0001690 ! ear [Term] id: OBA:0003618 name: zone of skin size def: "The size of a zone of skin." [AUTO:patterns/patterns/entity_attribute] synonym: "size of zone of skin" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0002096 ! skin morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000014 ! zone of skin relationship: characteristic_of UBERON:0000014 ! zone of skin [Term] id: OBA:0003722 name: jaw skeleton size def: "The size of a jaw skeleton." [AUTO:patterns/patterns/entity_attribute] synonym: "size of jaw skeleton" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000454 ! jaw morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001708 ! jaw skeleton relationship: characteristic_of UBERON:0001708 ! jaw skeleton [Term] id: OBA:0003760 name: cervical vertebra morphology def: "The morphology of a cervical vertebra." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of cervical vertebra" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002413 ! cervical vertebra relationship: characteristic_of_part_of UBERON:0002413 ! cervical vertebra [Term] id: OBA:0003763 name: metacarpal bone morphology def: "The morphology of a metacarpal bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of metacarpal bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000550 ! forelimb morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002374 ! metacarpal bone relationship: characteristic_of_part_of UBERON:0002374 ! metacarpal bone [Term] id: OBA:0003917 name: chest morphology def: "The morphology of a chest." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of chest" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001443 relationship: characteristic_of_part_of UBERON:0001443 [Term] id: OBA:0003980 name: supraoccipital bone size def: "The size of a supraoccipital bone." [AUTO:patterns/patterns/entity_attribute] synonym: "size of supraoccipital bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000078 ! supraoccipital bone morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0004747 ! supraoccipital bone relationship: characteristic_of UBERON:0004747 ! supraoccipital bone [Term] id: OBA:0004026 name: vertebral bone 1 morphology def: "The morphology of a vertebral bone 1." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of vertebral bone 1" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001092 ! vertebral bone 1 relationship: characteristic_of_part_of UBERON:0001092 ! vertebral bone 1 [Term] id: OBA:0004027 name: vertebral bone 2 morphology def: "The morphology of a vertebral bone 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of vertebral bone 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001093 ! vertebral bone 2 relationship: characteristic_of_part_of UBERON:0001093 ! vertebral bone 2 [Term] id: OBA:0004033 name: metatarsal bone length def: "The length of a metatarsal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "length of metatarsal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: FOVT:0001141 ! metapodial bone length is_a: OBA:0002251 ! metatarsal bone size intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001448 ! metatarsal bone [Term] id: OBA:0004048 name: lumbar vertebra length def: "The length of a lumbar vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "length of lumbar vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010518 ! lumbar vertebra size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002414 ! lumbar vertebra [Term] id: OBA:0004075 name: incisor tooth length def: "The length of a incisor tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "length of incisor tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000113 ! incisor size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001098 ! incisor tooth [Term] id: OBA:0004257 name: molar tooth size def: "The size of a molar tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "size of molar tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000112 ! tooth size is_a: OBA:VT0002689 ! molar morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003655 ! molar tooth relationship: characteristic_of UBERON:0003655 ! molar tooth [Term] id: OBA:0004448 name: cranium height def: "The height of a cranium." [AUTO:patterns/patterns/entity_attribute] synonym: "height of cranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010613 ! cranium size is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0003128 ! cranium [Term] id: OBA:0004782 name: pubic symphysis morphology def: "The morphology of a pubic symphysis." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of pubic symphysis" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003356 ! pelvic girdle bone/zone morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003699 ! pubic symphysis relationship: characteristic_of_part_of UBERON:0003699 ! pubic symphysis [Term] id: OBA:0004840 name: navicular bone of pes morphology def: "The morphology of a navicular bone of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of navicular bone of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000189 ! navicular bone of pes quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001451 ! navicular bone of pes [Term] id: OBA:0004900 name: vomer size def: "The size of a vomer." [AUTO:patterns/patterns/entity_attribute] synonym: "size of vomer" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000098 ! vomer bone morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002396 ! vomer relationship: characteristic_of UBERON:0002396 ! vomer [Term] id: OBA:0004993 name: fused sacrum morphology def: "The morphology of a fused sacrum." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of fused sacrum" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003690 ! fused sacrum relationship: characteristic_of_part_of UBERON:0003690 ! fused sacrum [Term] id: OBA:0005278 name: foramen magnum morphology def: "The morphology of a foramen magnum." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of foramen magnum" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000438 ! skull morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003687 ! foramen magnum relationship: characteristic_of_part_of UBERON:0003687 ! foramen magnum [Term] id: OBA:0005564 name: cranium length def: "The length of a cranium." [AUTO:patterns/patterns/entity_attribute] synonym: "length of cranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010613 ! cranium size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003128 ! cranium [Term] id: OBA:0006029 name: horn size def: "The size of a horn." [AUTO:patterns/patterns/entity_attribute] synonym: "size of horn" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0006030 ! horn morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0006967 ! horn relationship: characteristic_of UBERON:0006967 ! horn [Term] id: OBA:0006030 name: horn morphology def: "The morphology of a horn." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of horn" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0006967 ! horn relationship: characteristic_of_part_of UBERON:0006967 ! horn [Term] id: OBA:1000048 name: manus length namespace: oba def: "The length of a manus." [AUTO:patterns/patterns/entity_attribute] synonym: "hand length" EXACT [] synonym: "length of manus" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "manus length trait" EXACT [GOC:TermGenie] is_a: OBA:0002188 ! manus size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002398 ! manus created_by: cjmungall creation_date: 2014-01-27T23:51:00Z [Term] id: OBA:1000049 name: pes length namespace: oba def: "The length of a pes." [AUTO:patterns/patterns/entity_attribute] synonym: "foot length" EXACT [] synonym: "hindfoot length" EXACT [] synonym: "length of pes" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "pes length trait" EXACT [GOC:TermGenie] is_a: OBA:VT0000573 ! hind paw size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002387 ! pes relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 created_by: cjmungall creation_date: 2014-01-27T23:51:06Z [Term] id: OBA:1000112 name: tooth size namespace: oba def: "The size of a calcareous tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "calcareous tooth size trait" EXACT [GOC:TermGenie] synonym: "size of calcareous tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0002100 ! tooth morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001091 ! calcareous tooth relationship: characteristic_of UBERON:0001091 ! calcareous tooth created_by: cjmungall creation_date: 2014-07-27T01:19:07Z [Term] id: OBA:1000113 name: incisor size namespace: oba def: "The size of a incisor tooth." [AUTO:patterns/patterns/entity_attribute] synonym: "incisor tooth size trait" EXACT [GOC:TermGenie] synonym: "size of incisor tooth" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000112 ! tooth size is_a: OBA:VT0005358 ! incisor morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001098 ! incisor tooth relationship: characteristic_of UBERON:0001098 ! incisor tooth created_by: cjmungall creation_date: 2014-07-27T01:19:11Z [Term] id: OBA:1000148 name: proximal epiphysis of tibia quality def: "The quality of a proximal epiphysis of tibia." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal epiphysis of tibia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000340 ! tibia quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0008772 ! proximal epiphysis of tibia relationship: characteristic_of_part_of UBERON:0008772 ! proximal epiphysis of tibia [Term] id: OBA:1000150 name: proximal phalanx of manual digit 5 quality def: "The quality of a proximal phalanx of manual digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004331 ! proximal phalanx of manual digit 5 relationship: characteristic_of_part_of UBERON:0004331 ! proximal phalanx of manual digit 5 [Term] id: OBA:1000158 name: manual digit 4 phalanx quality def: "The quality of a manual digit 4 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of manual digit 4 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000632 ! phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003638 ! manual digit 4 phalanx relationship: characteristic_of_part_of UBERON:0003638 ! manual digit 4 phalanx [Term] id: OBA:1000161 name: pedal digit 1 phalanx quality def: "The quality of a pedal digit 1 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 1 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003640 ! pedal digit 1 phalanx relationship: characteristic_of_part_of UBERON:0003640 ! pedal digit 1 phalanx [Term] id: OBA:1000170 name: proximal phalanx of pedal digit 2 quality def: "The quality of a proximal phalanx of pedal digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000353 ! pedal digit 2 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004333 ! proximal phalanx of pedal digit 2 relationship: characteristic_of_part_of UBERON:0004333 ! proximal phalanx of pedal digit 2 [Term] id: OBA:1000175 name: middle phalanx of pedal digit 5 quality def: "The quality of a middle phalanx of pedal digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000329 ! pedal digit 5 phalanx quality is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004327 ! middle phalanx of pedal digit 5 relationship: characteristic_of_part_of UBERON:0004327 ! middle phalanx of pedal digit 5 [Term] id: OBA:1000177 name: ilium quality def: "The quality of a ilium." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of ilium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001273 ! ilium relationship: characteristic_of_part_of UBERON:0001273 ! ilium [Term] id: OBA:1000178 name: proximal phalanx of manual digit 3 quality def: "The quality of a proximal phalanx of manual digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004329 ! proximal phalanx of manual digit 3 relationship: characteristic_of_part_of UBERON:0004329 ! proximal phalanx of manual digit 3 [Term] id: OBA:1000180 name: distal epiphysis of femur quality def: "The quality of a distal epiphysis of femur." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal epiphysis of femur" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000621 ! femur quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004406 ! distal epiphysis of femur relationship: characteristic_of_part_of UBERON:0004406 ! distal epiphysis of femur [Term] id: OBA:1000189 name: navicular bone of pes quality def: "The quality of a navicular bone of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of navicular bone of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001451 ! navicular bone of pes relationship: characteristic_of_part_of UBERON:0001451 ! navicular bone of pes [Term] id: OBA:1000190 name: distal phalanx of manus quality def: "The quality of a distal phalanx of manus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000632 ! phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003865 ! distal phalanx of manus relationship: characteristic_of_part_of UBERON:0003865 ! distal phalanx of manus [Term] id: OBA:1000196 name: distal epiphysis of tibia quality def: "The quality of a distal epiphysis of tibia." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal epiphysis of tibia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000340 ! tibia quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004405 ! distal epiphysis of tibia relationship: characteristic_of_part_of UBERON:0004405 ! distal epiphysis of tibia [Term] id: OBA:1000204 name: proximal phalanx of manual digit 4 quality def: "The quality of a proximal phalanx of manual digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000158 ! manual digit 4 phalanx quality is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004330 ! proximal phalanx of manual digit 4 relationship: characteristic_of_part_of UBERON:0004330 ! proximal phalanx of manual digit 4 [Term] id: OBA:1000208 name: middle phalanx of manual digit 4 quality def: "The quality of a middle phalanx of manual digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of manual digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000158 ! manual digit 4 phalanx quality is_a: OBA:1000382 ! middle phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004322 ! middle phalanx of manual digit 4 relationship: characteristic_of_part_of UBERON:0004322 ! middle phalanx of manual digit 4 [Term] id: OBA:1000210 name: distal phalanx of manual digit 3 quality def: "The quality of a distal phalanx of manual digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004312 ! distal phalanx of manual digit 3 relationship: characteristic_of_part_of UBERON:0004312 ! distal phalanx of manual digit 3 [Term] id: OBA:1000212 name: proximal phalanx of pes quality def: "The quality of a proximal phalanx of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003868 ! proximal phalanx of pes relationship: characteristic_of_part_of UBERON:0003868 ! proximal phalanx of pes [Term] id: OBA:1000215 name: proximal phalanx of pedal digit 4 quality def: "The quality of a proximal phalanx of pedal digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000575 ! pedal digit 4 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004335 ! proximal phalanx of pedal digit 4 relationship: characteristic_of_part_of UBERON:0004335 ! proximal phalanx of pedal digit 4 [Term] id: OBA:1000228 name: proximal phalanx of manual digit 2 quality def: "The quality of a proximal phalanx of manual digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manual digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000610 ! proximal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004328 ! proximal phalanx of manual digit 2 relationship: characteristic_of_part_of UBERON:0004328 ! proximal phalanx of manual digit 2 [Term] id: OBA:1000240 name: proximal phalanx of pedal digit 5 quality def: "The quality of a proximal phalanx of pedal digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000329 ! pedal digit 5 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004336 ! proximal phalanx of pedal digit 5 relationship: characteristic_of_part_of UBERON:0004336 ! proximal phalanx of pedal digit 5 [Term] id: OBA:1000249 name: basicranium quality def: "The quality of a basicranium." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of basicranium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000429 ! skull quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0002517 ! basicranium relationship: characteristic_of_part_of UBERON:0002517 ! basicranium [Term] id: OBA:1000254 name: metatarsal bone of digit 5 quality def: "The quality of a metatarsal bone of digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of metatarsal bone of digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003654 ! metatarsal bone of digit 5 relationship: characteristic_of_part_of UBERON:0003654 ! metatarsal bone of digit 5 [Term] id: OBA:1000271 name: distal phalanx of manual digit 5 quality def: "The quality of a distal phalanx of manual digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004314 ! distal phalanx of manual digit 5 relationship: characteristic_of_part_of UBERON:0004314 ! distal phalanx of manual digit 5 [Term] id: OBA:1000283 name: distal phalanx of pedal digit 5 quality def: "The quality of a distal phalanx of pedal digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000329 ! pedal digit 5 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004319 ! distal phalanx of pedal digit 5 relationship: characteristic_of_part_of UBERON:0004319 ! distal phalanx of pedal digit 5 [Term] id: OBA:1000291 name: distal phalanx of manual digit 4 quality def: "The quality of a distal phalanx of manual digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000158 ! manual digit 4 phalanx quality is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004313 ! distal phalanx of manual digit 4 relationship: characteristic_of_part_of UBERON:0004313 ! distal phalanx of manual digit 4 [Term] id: OBA:1000299 name: middle phalanx of pedal digit 4 quality def: "The quality of a middle phalanx of pedal digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000492 ! middle phalanx of pes quality is_a: OBA:1000575 ! pedal digit 4 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004326 ! middle phalanx of pedal digit 4 relationship: characteristic_of_part_of UBERON:0004326 ! middle phalanx of pedal digit 4 [Term] id: OBA:1000300 name: ulna quality def: "The quality of a ulna." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of ulna" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001424 ! ulna relationship: characteristic_of_part_of UBERON:0001424 ! ulna [Term] id: OBA:1000304 name: proximal epiphysis of radius quality def: "The quality of a proximal epiphysis of radius." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal epiphysis of radius" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000591 ! radius bone quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004413 ! proximal epiphysis of radius relationship: characteristic_of_part_of UBERON:0004413 ! proximal epiphysis of radius [Term] id: OBA:1000325 name: distal phalanx of manual digit 2 quality def: "The quality of a distal phalanx of manual digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of manual digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000190 ! distal phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004311 ! distal phalanx of manual digit 2 relationship: characteristic_of_part_of UBERON:0004311 ! distal phalanx of manual digit 2 [Term] id: OBA:1000326 name: humerus quality def: "The quality of a humerus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of humerus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0000976 ! humerus relationship: characteristic_of_part_of UBERON:0000976 ! humerus [Term] id: OBA:1000328 name: distal phalanx of pedal digit 3 quality def: "The quality of a distal phalanx of pedal digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000378 ! pedal digit 3 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: characteristic_of_part_of UBERON:0004317 ! distal phalanx of pedal digit 3 [Term] id: OBA:1000329 name: pedal digit 5 phalanx quality def: "The quality of a pedal digit 5 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 5 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003863 ! pedal digit 5 phalanx relationship: characteristic_of_part_of UBERON:0003863 ! pedal digit 5 phalanx [Term] id: OBA:1000334 name: acetabular part of hip bone quality def: "The quality of a acetabular part of hip bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of acetabular part of hip bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000177 ! ilium quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001269 ! acetabular part of hip bone relationship: characteristic_of_part_of UBERON:0001269 ! acetabular part of hip bone [Term] id: OBA:1000335 name: cuspid quality def: "The quality of a cuspid." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of cuspid" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003674 ! cuspid relationship: characteristic_of_part_of UBERON:0003674 ! cuspid [Term] id: OBA:1000340 name: tibia quality def: "The quality of a tibia." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of tibia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0000979 ! tibia relationship: characteristic_of_part_of UBERON:0000979 ! tibia [Term] id: OBA:1000353 name: pedal digit 2 phalanx quality def: "The quality of a pedal digit 2 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 2 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003641 ! pedal digit 2 phalanx relationship: characteristic_of_part_of UBERON:0003641 ! pedal digit 2 phalanx [Term] id: OBA:1000378 name: pedal digit 3 phalanx quality def: "The quality of a pedal digit 3 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 3 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003642 ! pedal digit 3 phalanx relationship: characteristic_of_part_of UBERON:0003642 ! pedal digit 3 phalanx [Term] id: OBA:1000380 name: diaphysis of radius quality def: "The quality of a diaphysis of radius." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of diaphysis of radius" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000552 ! diaphysis quality is_a: OBA:1000591 ! radius bone quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001028 ! diaphysis of radius relationship: characteristic_of_part_of UBERON:0001028 ! diaphysis of radius [Term] id: OBA:1000382 name: middle phalanx of manus quality def: "The quality of a middle phalanx of manus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of manus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000632 ! phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003864 ! middle phalanx of manus relationship: characteristic_of_part_of UBERON:0003864 ! middle phalanx of manus [Term] id: OBA:1000389 name: middle phalanx of pedal digit 2 quality def: "The quality of a middle phalanx of pedal digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000353 ! pedal digit 2 phalanx quality is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004324 ! middle phalanx of pedal digit 2 relationship: characteristic_of_part_of UBERON:0004324 ! middle phalanx of pedal digit 2 [Term] id: OBA:1000394 name: proximal epiphysis of humerus quality def: "The quality of a proximal epiphysis of humerus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal epiphysis of humerus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000326 ! humerus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004411 ! proximal epiphysis of humerus relationship: characteristic_of_part_of UBERON:0004411 ! proximal epiphysis of humerus [Term] id: OBA:1000409 name: glenoid fossa quality def: "The quality of a glenoid fossa." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of glenoid fossa" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0006657 ! glenoid fossa relationship: characteristic_of_part_of UBERON:0006657 ! glenoid fossa [Term] id: OBA:1000413 name: metatarsal bone of digit 3 quality def: "The quality of a metatarsal bone of digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of metatarsal bone of digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: characteristic_of_part_of UBERON:0003652 ! metatarsal bone of digit 3 [Term] id: OBA:1000416 name: ischium quality def: "The quality of a ischium." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of ischium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001274 ! ischium relationship: characteristic_of_part_of UBERON:0001274 ! ischium [Term] id: OBA:1000419 name: middle phalanx of pedal digit 3 quality def: "The quality of a middle phalanx of pedal digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pedal digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000378 ! pedal digit 3 phalanx quality is_a: OBA:1000492 ! middle phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004325 ! middle phalanx of pedal digit 3 relationship: characteristic_of_part_of UBERON:0004325 ! middle phalanx of pedal digit 3 [Term] id: OBA:1000422 name: proximal phalanx of pedal digit 3 quality def: "The quality of a proximal phalanx of pedal digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000212 ! proximal phalanx of pes quality is_a: OBA:1000378 ! pedal digit 3 phalanx quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004334 ! proximal phalanx of pedal digit 3 relationship: characteristic_of_part_of UBERON:0004334 ! proximal phalanx of pedal digit 3 [Term] id: OBA:1000427 name: distal phalanx of pedal digit 2 quality def: "The quality of a distal phalanx of pedal digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000353 ! pedal digit 2 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: characteristic_of_part_of UBERON:0004316 ! distal phalanx of pedal digit 2 [Term] id: OBA:1000429 name: skull quality def: "The quality of a skull." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of skull" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003129 ! skull relationship: characteristic_of_part_of UBERON:0003129 ! skull [Term] id: OBA:1000436 name: molar tooth quality def: "The quality of a molar tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of molar tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003655 ! molar tooth relationship: characteristic_of_part_of UBERON:0003655 ! molar tooth [Term] id: OBA:1000449 name: talus quality def: "The quality of a talus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of talus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0002395 ! talus relationship: characteristic_of_part_of UBERON:0002395 ! talus [Term] id: OBA:1000450 name: facial skeleton quality def: "The quality of a facial skeleton." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of facial skeleton" EXACT [obo:oba/patterns/entity_attribute_part_of] synonym: "viscerocranium quality" RELATED [] is_a: OBA:1000429 ! skull quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0011156 ! facial skeleton relationship: characteristic_of_part_of UBERON:0011156 ! facial skeleton relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:1000461 name: proximal phalanx of pedal digit 1 quality def: "The quality of a proximal phalanx of pedal digit 1." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of pedal digit 1" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000161 ! pedal digit 1 phalanx quality is_a: OBA:1000212 ! proximal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004332 ! proximal phalanx of pedal digit 1 relationship: characteristic_of_part_of UBERON:0004332 ! proximal phalanx of pedal digit 1 [Term] id: OBA:1000462 name: hard palate quality def: "The quality of a hard palate." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of hard palate" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003216 ! hard palate relationship: characteristic_of_part_of UBERON:0003216 ! hard palate [Term] id: OBA:1000468 name: distal phalanx of pedal digit 4 quality def: "The quality of a distal phalanx of pedal digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000575 ! pedal digit 4 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: characteristic_of_part_of UBERON:0004318 ! distal phalanx of pedal digit 4 [Term] id: OBA:1000491 name: metatarsal bone of digit 2 quality def: "The quality of a metatarsal bone of digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of metatarsal bone of digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003651 ! metatarsal bone of digit 2 relationship: characteristic_of_part_of UBERON:0003651 ! metatarsal bone of digit 2 [Term] id: OBA:1000492 name: middle phalanx of pes quality def: "The quality of a middle phalanx of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003866 ! middle phalanx of pes relationship: characteristic_of_part_of UBERON:0003866 ! middle phalanx of pes [Term] id: OBA:1000501 name: phalanx of pes quality def: "The quality of a phalanx of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of phalanx of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001449 ! phalanx of pes relationship: characteristic_of_part_of UBERON:0001449 ! phalanx of pes [Term] id: OBA:1000510 name: middle phalanx of manual digit 2 quality def: "The quality of a middle phalanx of manual digit 2." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of manual digit 2" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000382 ! middle phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004320 ! middle phalanx of manual digit 2 relationship: characteristic_of_part_of UBERON:0004320 ! middle phalanx of manual digit 2 [Term] id: OBA:1000526 name: middle phalanx of manual digit 3 quality def: "The quality of a middle phalanx of manual digit 3." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of manual digit 3" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000382 ! middle phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004321 ! middle phalanx of manual digit 3 relationship: characteristic_of_part_of UBERON:0004321 ! middle phalanx of manual digit 3 [Term] id: OBA:1000545 name: ovary quality def: "The quality of a ovary." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of ovary" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0000992 ! ovary relationship: characteristic_of_part_of UBERON:0000992 ! ovary [Term] id: OBA:1000552 name: diaphysis quality def: "The quality of a diaphysis." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of diaphysis" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004769 ! diaphysis relationship: characteristic_of_part_of UBERON:0004769 ! diaphysis [Term] id: OBA:1000555 name: middle phalanx of manual digit 5 quality def: "The quality of a middle phalanx of manual digit 5." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of middle phalanx of manual digit 5" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000382 ! middle phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004323 ! middle phalanx of manual digit 5 relationship: characteristic_of_part_of UBERON:0004323 ! middle phalanx of manual digit 5 [Term] id: OBA:1000568 name: distal epiphysis of humerus quality def: "The quality of a distal epiphysis of humerus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal epiphysis of humerus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000326 ! humerus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004404 ! distal epiphysis of humerus relationship: characteristic_of_part_of UBERON:0004404 ! distal epiphysis of humerus [Term] id: OBA:1000571 name: distal phalanx of pedal digit 1 quality def: "The quality of a distal phalanx of pedal digit 1." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pedal digit 1" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000161 ! pedal digit 1 phalanx quality is_a: OBA:1000628 ! distal phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004315 ! distal phalanx of pedal digit 1 relationship: characteristic_of_part_of UBERON:0004315 ! distal phalanx of pedal digit 1 [Term] id: OBA:1000572 name: fibula quality def: "The quality of a fibula." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of fibula" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001446 ! fibula relationship: characteristic_of_part_of UBERON:0001446 ! fibula [Term] id: OBA:1000575 name: pedal digit 4 phalanx quality def: "The quality of a pedal digit 4 phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of pedal digit 4 phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003862 ! pedal digit 4 phalanx relationship: characteristic_of_part_of UBERON:0003862 ! pedal digit 4 phalanx [Term] id: OBA:1000578 name: incisor tooth quality def: "The quality of a incisor tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of incisor tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001098 ! incisor tooth relationship: characteristic_of_part_of UBERON:0001098 ! incisor tooth [Term] id: OBA:1000591 name: radius bone quality def: "The quality of a radius bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of radius bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001423 ! radius bone relationship: characteristic_of_part_of UBERON:0001423 ! radius bone [Term] id: OBA:1000593 name: premolar tooth quality def: "The quality of a premolar tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of premolar tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0007120 ! premolar tooth relationship: characteristic_of_part_of UBERON:0007120 ! premolar tooth [Term] id: OBA:1000597 name: metatarsal bone of digit 1 quality def: "The quality of a metatarsal bone of digit 1." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of metatarsal bone of digit 1" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003650 ! metatarsal bone of digit 1 relationship: characteristic_of_part_of UBERON:0003650 ! metatarsal bone of digit 1 [Term] id: OBA:1000600 name: distal epiphysis of radius quality def: "The quality of a distal epiphysis of radius." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal epiphysis of radius" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000591 ! radius bone quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0004407 ! distal epiphysis of radius relationship: characteristic_of_part_of UBERON:0004407 ! distal epiphysis of radius [Term] id: OBA:1000610 name: proximal phalanx of manus quality def: "The quality of a proximal phalanx of manus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of proximal phalanx of manus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000632 ! phalanx of manus quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0002234 ! proximal phalanx of manus relationship: characteristic_of_part_of UBERON:0002234 ! proximal phalanx of manus [Term] id: OBA:1000611 name: metatarsal bone of digit 4 quality def: "The quality of a metatarsal bone of digit 4." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of metatarsal bone of digit 4" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: characteristic_of_part_of UBERON:0003653 ! metatarsal bone of digit 4 [Term] id: OBA:1000621 name: femur quality def: "The quality of a femur." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of femur" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0000981 ! femur relationship: characteristic_of_part_of UBERON:0000981 ! femur [Term] id: OBA:1000628 name: distal phalanx of pes quality def: "The quality of a distal phalanx of pes." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of distal phalanx of pes" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000501 ! phalanx of pes quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0003867 ! distal phalanx of pes relationship: characteristic_of_part_of UBERON:0003867 ! distal phalanx of pes [Term] id: OBA:1000632 name: phalanx of manus quality def: "The quality of a phalanx of manus." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of phalanx of manus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001436 ! phalanx of manus relationship: characteristic_of_part_of UBERON:0001436 ! phalanx of manus [Term] id: OBA:1000675 name: transverse process of vertebra quality def: "The quality of a transverse process of vertebra." [obo:oba/patterns/entity_attribute_part_of] synonym: "quality of transverse process of vertebra" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of_part_of UBERON:0001077 ! transverse process of vertebra relationship: characteristic_of_part_of UBERON:0001077 ! transverse process of vertebra [Term] id: OBA:VT0000017 name: outer ear size trait def: "The size of a external ear." [AUTO:patterns/patterns/entity_attribute] synonym: "size of external ear" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002845 ! external ear morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001691 ! external ear relationship: characteristic_of UBERON:0001691 ! external ear [Term] id: OBA:VT0000074 name: neurocranium morphology trait def: "The morphology of a neurocranium." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of neurocranium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0010612 ! cranium morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001703 ! neurocranium relationship: characteristic_of_part_of UBERON:0001703 ! neurocranium [Term] id: OBA:VT0000078 name: supraoccipital bone morphology trait def: "The morphology of a supraoccipital bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of supraoccipital bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000074 ! neurocranium morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0004747 ! supraoccipital bone relationship: characteristic_of_part_of UBERON:0004747 ! supraoccipital bone [Term] id: OBA:VT0000098 name: vomer bone morphology trait def: "The morphology of a vomer." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of vomer" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000454 ! jaw morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002396 ! vomer relationship: characteristic_of_part_of UBERON:0002396 ! vomer [Term] id: OBA:VT0000137 name: vertebra morphology trait def: "The morphology of a vertebra." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of vertebra" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002412 ! vertebra relationship: characteristic_of_part_of UBERON:0002412 ! vertebra [Term] id: OBA:VT0000149 name: scapula morphology trait def: "The morphology of a scapula." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of scapula" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0006849 ! scapula relationship: characteristic_of_part_of UBERON:0006849 ! scapula [Term] id: OBA:VT0000438 name: skull morphology trait def: "The morphology of a skull." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of skull" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000429 ! skull quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003129 ! skull [Term] id: OBA:VT0000443 name: snout morphology trait def: "The morphology of a snout." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of snout" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0006333 ! snout relationship: characteristic_of_part_of UBERON:0006333 ! snout [Term] id: OBA:VT0000446 name: snout length def: "The length of a snout." [AUTO:patterns/patterns/entity_attribute] synonym: "length of snout" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "muzzle length" EXACT [] is_a: OBA:VT0000443 ! snout morphology trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0006333 ! snout relationship: characteristic_of UBERON:0006333 ! snout relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0000454 name: jaw morphology trait def: "The morphology of a jaw skeleton." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of jaw skeleton" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0005274 ! facial skeleton morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001708 ! jaw skeleton relationship: characteristic_of_part_of UBERON:0001708 ! jaw skeleton [Term] id: OBA:VT0000458 name: mandible morphology trait def: "The morphology of a lower jaw region." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of lower jaw region" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001710 ! lower jaw region relationship: characteristic_of_part_of UBERON:0001710 ! lower jaw region [Term] id: OBA:VT0000482 name: fibula length def: "The length of a fibula." [AUTO:patterns/patterns/entity_attribute] synonym: "fibula greatest length (GL)" EXACT [] synonym: "length of fibula" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002384 ! fibula size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001446 ! fibula relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0000550 name: forelimb morphology trait def: "The morphology of a forelimb." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of forelimb" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002102 ! forelimb relationship: characteristic_of_part_of UBERON:0002102 ! forelimb [Term] id: OBA:VT0000552 name: radius morphology trait def: "The morphology of a radius bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of radius bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000591 ! radius bone quality is_a: OBA:VT0000550 ! forelimb morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001423 ! radius bone [Term] id: OBA:VT0000558 name: tibia morphology trait def: "The morphology of a tibia." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of tibia" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000340 ! tibia quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0000979 ! tibia [Term] id: OBA:VT0000559 name: femur morphology trait def: "The morphology of a femur." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of femur" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000621 ! femur quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0000981 ! femur [Term] id: OBA:VT0000573 name: hind paw size trait def: "The size of a pes." [AUTO:patterns/patterns/entity_attribute] synonym: "size of pes" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002387 ! pes relationship: characteristic_of UBERON:0002387 ! pes [Term] id: OBA:VT0000588 name: tail diameter def: "The diameter of a tail." [AUTO:patterns/patterns/entity_attribute] synonym: "diameter of tail" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0003456 ! tail size trait is_a: PATO:0001334 ! diameter intersection_of: PATO:0001334 ! diameter intersection_of: characteristic_of UBERON:0002415 ! tail [Term] id: OBA:VT0001126 name: ovary morphology trait def: "The morphology of a ovary." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of ovary" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000545 ! ovary quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0000992 ! ovary [Term] id: OBA:VT0001127 name: ovary size trait def: "The size of a ovary." [AUTO:patterns/patterns/entity_attribute] synonym: "size of ovary" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002017 ! gonad size is_a: OBA:VT0001126 ! ovary morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000992 ! ovary relationship: characteristic_of UBERON:0000992 ! ovary [Term] id: OBA:VT0001146 name: testes morphology trait def: "The morphology of a testis." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of testis" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0000473 ! testis relationship: characteristic_of_part_of UBERON:0000473 ! testis [Term] id: OBA:VT0001148 name: testes size trait def: "The size of a testis." [AUTO:patterns/patterns/entity_attribute] synonym: "size of testis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002017 ! gonad size is_a: OBA:VT0001146 ! testes morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000473 ! testis relationship: characteristic_of UBERON:0000473 ! testis [Term] id: OBA:VT0001253 name: body height def: "The height of a multicellular organism." [AUTO:patterns/patterns/entity_attribute] synonym: "height of multicellular organism" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100005 ! body size trait is_a: PATO:0000119 ! height intersection_of: PATO:0000119 ! height intersection_of: characteristic_of UBERON:0000468 ! multicellular organism [Term] id: OBA:VT0001256 name: body length def: "The length of a multicellular organism." [AUTO:patterns/patterns/entity_attribute] synonym: "length of multicellular organism" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100005 ! body size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000468 ! multicellular organism [Term] id: OBA:VT0001259 name: body mass def: "The mass of a multicellular organism." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of multicellular organism" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010454 ! organism trait is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0000468 ! multicellular organism [Term] id: OBA:VT0002096 name: skin morphology trait def: "The morphology of a zone of skin." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of zone of skin" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0000014 ! zone of skin relationship: characteristic_of_part_of UBERON:0000014 ! zone of skin [Term] id: OBA:VT0002100 name: tooth morphology trait def: "The morphology of a calcareous tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of calcareous tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001091 ! calcareous tooth relationship: characteristic_of_part_of UBERON:0001091 ! calcareous tooth [Term] id: OBA:VT0002102 name: ear morphology trait def: "The morphology of a ear." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of ear" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001690 ! ear relationship: characteristic_of_part_of UBERON:0001690 ! ear [Term] id: OBA:VT0002111 name: tail morphology trait def: "The morphology of a tail." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of tail" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002415 ! tail relationship: characteristic_of_part_of UBERON:0002415 ! tail [Term] id: OBA:VT0002187 name: fibula morphology trait def: "The morphology of a fibula." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of fibula" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000572 ! fibula quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001446 ! fibula [Term] id: OBA:VT0002236 name: internal nares morphology trait def: "The morphology of a posterior nasal aperture." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of posterior nasal aperture" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0010612 ! cranium morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0004771 ! posterior nasal aperture relationship: characteristic_of_part_of UBERON:0004771 ! posterior nasal aperture [Term] id: OBA:VT0002543 name: phalanx length def: "The length of a phalanx." [AUTO:patterns/patterns/entity_attribute] synonym: "length of phalanx" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002674 ! phalanx size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0003221 ! phalanx [Term] id: OBA:VT0002689 name: molar morphology trait def: "The morphology of a molar tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of molar tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000436 ! molar tooth quality is_a: OBA:VT0002100 ! tooth morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003655 ! molar tooth [Term] id: OBA:VT0002758 name: tail length def: "The length of a tail." [AUTO:patterns/patterns/entity_attribute] synonym: "length of tail" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0003456 ! tail size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002415 ! tail [Term] id: OBA:VT0003047 name: thoracic vertebra morphology trait def: "The morphology of a thoracic vertebra." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of thoracic vertebra" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002347 ! thoracic vertebra relationship: characteristic_of_part_of UBERON:0002347 ! thoracic vertebra [Term] id: OBA:VT0003072 name: metatarsus morphology trait def: "The morphology of a metatarsal bone." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of metatarsal bone" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001448 ! metatarsal bone relationship: characteristic_of_part_of UBERON:0001448 ! metatarsal bone [Term] id: OBA:VT0003104 name: skull size trait def: "The size of a skull." [AUTO:patterns/patterns/entity_attribute] synonym: "size of skull" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000438 ! skull morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003129 ! skull relationship: characteristic_of UBERON:0003129 ! skull [Term] id: OBA:VT0003456 name: tail size trait def: "The size of a tail." [AUTO:patterns/patterns/entity_attribute] synonym: "size of tail" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0002111 ! tail morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002415 ! tail relationship: characteristic_of UBERON:0002415 ! tail [Term] id: OBA:VT0003756 name: hard palate morphology trait def: "The morphology of a hard palate." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of hard palate" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000462 ! hard palate quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003216 ! hard palate [Term] id: OBA:VT0004214 name: long bone diaphysis morphology trait def: "The morphology of a diaphysis." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of diaphysis" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000552 ! diaphysis quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0004769 ! diaphysis [Term] id: OBA:VT0004340 name: scapula length def: "The length of a scapula." [AUTO:patterns/patterns/entity_attribute] synonym: "length of scapula" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "scapula diagonal height(DHA)" EXACT [] synonym: "scapula maximal length (M1)" EXACT [] is_a: OBA:VT0004343 ! scapula size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0006849 ! scapula relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0004343 name: scapula size trait def: "The size of a scapula." [AUTO:patterns/patterns/entity_attribute] synonym: "size of scapula" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000149 ! scapula morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0006849 ! scapula relationship: characteristic_of UBERON:0006849 ! scapula [Term] id: OBA:VT0004347 name: scapular spine morphology trait def: "The morphology of a scapula spine." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of scapula spine" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000149 ! scapula morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0004651 ! scapula spine relationship: characteristic_of_part_of UBERON:0004651 ! scapula spine [Term] id: OBA:VT0004348 name: femur length def: "The length of a femur." [AUTO:patterns/patterns/entity_attribute] synonym: "length of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000981 ! femur [Term] id: OBA:VT0004350 name: humerus length def: "The length of a humerus." [AUTO:patterns/patterns/entity_attribute] synonym: "length of humerus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000976 ! humerus [Term] id: OBA:VT0004355 name: radius length def: "The length of a radius bone." [AUTO:patterns/patterns/entity_attribute] synonym: "length of radius bone" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "radius greatest length (GL)" EXACT [] synonym: "radius maximal length (M1)" EXACT [] is_a: OBA:0002374 ! radius bone size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001423 ! radius bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0004357 name: tibia length def: "The length of a tibia." [AUTO:patterns/patterns/entity_attribute] synonym: "length of tibia" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "tibia greatest length (GL)" EXACT [] synonym: "tibia maximal length (M1)" EXACT [] is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0000979 ! tibia relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0004370 name: ulna length def: "The length of a ulna." [AUTO:patterns/patterns/entity_attribute] synonym: "length of ulna" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "ulna greatest length (GL)" EXACT [] synonym: "ulna maximal length (M1)" EXACT [] is_a: OBA:0002379 ! ulna size is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0001424 ! ulna relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0005108 name: ulna morphology trait def: "The morphology of a ulna." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of ulna" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000300 ! ulna quality is_a: OBA:VT0000550 ! forelimb morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001424 ! ulna [Term] id: OBA:VT0005109 name: talus morphology trait def: "The morphology of a talus." [obo:oba/patterns/entity_attribute_part_of] synonym: "astragalus morphology trait" EXACT [] synonym: "morphology of talus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000449 ! talus quality is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002395 ! talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0005110 name: talus size trait def: "The size of a talus." [AUTO:patterns/patterns/entity_attribute] synonym: "astragalus size trait" EXACT [] synonym: "size of talus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005109 ! talus morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002395 ! talus relationship: characteristic_of UBERON:0002395 ! talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0005273 name: cranial base morphology trait def: "The morphology of a basicranium." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of basicranium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000249 ! basicranium quality is_a: OBA:VT0000074 ! neurocranium morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002517 ! basicranium [Term] id: OBA:VT0005274 name: facial skeleton morphology def: "The morphology of a facial skeleton." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of facial skeleton" EXACT [obo:oba/patterns/entity_attribute_part_of] synonym: "viscerocranium morphology trait" RELATED [] is_a: OBA:1000450 ! facial skeleton quality is_a: OBA:VT0000438 ! skull morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0011156 ! facial skeleton relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT0005296 name: humerus morphology trait def: "The morphology of a humerus." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of humerus" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000326 ! humerus quality is_a: OBA:VT0000550 ! forelimb morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0000976 ! humerus [Term] id: OBA:VT0005306 name: phalanx morphology trait def: "The morphology of a phalanx." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of phalanx" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003221 ! phalanx relationship: characteristic_of_part_of UBERON:0003221 ! phalanx [Term] id: OBA:VT0005353 name: patella morphology trait def: "The morphology of a patella." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of patella" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: PATO:0000051 ! morphology intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002446 ! patella relationship: characteristic_of_part_of UBERON:0002446 ! patella [Term] id: OBA:VT0005354 name: ilium morphology trait def: "The morphology of a ilium." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of ilium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003356 ! pelvic girdle bone/zone morphology is_a: OBA:1000177 ! ilium quality intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001273 ! ilium [Term] id: OBA:VT0005358 name: incisor morphology trait def: "The morphology of a incisor tooth." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of incisor tooth" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:1000578 ! incisor tooth quality is_a: OBA:VT0002100 ! tooth morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001098 ! incisor tooth [Term] id: OBA:VT0010009 name: femur mass def: "The mass of a femur." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000621 ! femur quality is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0000981 ! femur relationship: characteristic_of UBERON:0000981 ! femur [Term] id: OBA:VT0010013 name: humerus mass def: "The mass of a humerus." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of humerus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000326 ! humerus quality is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0000976 ! humerus relationship: characteristic_of UBERON:0000976 ! humerus [Term] id: OBA:VT0010014 name: femur circumference def: "The circumference of a femur." [AUTO:patterns/patterns/entity_attribute] synonym: "circumference of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0000981 ! femur [Term] id: OBA:VT0010015 name: tibia mass def: "The mass of a tibia." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of tibia" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000340 ! tibia quality is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0000979 ! tibia relationship: characteristic_of UBERON:0000979 ! tibia [Term] id: OBA:VT0010023 name: forelimb length def: "The length of a forelimb." [AUTO:patterns/patterns/entity_attribute] synonym: "length of forelimb" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000550 ! forelimb morphology trait is_a: PATO:0000122 ! length intersection_of: PATO:0000122 ! length intersection_of: characteristic_of UBERON:0002102 ! forelimb relationship: characteristic_of UBERON:0002102 ! forelimb [Term] id: OBA:VT0010087 name: ischium morphology trait def: "The morphology of a ischium." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of ischium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:0003356 ! pelvic girdle bone/zone morphology is_a: OBA:1000416 ! ischium quality intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0001274 ! ischium [Term] id: OBA:VT0010375 name: ovary diameter def: "The diameter of a ovary." [AUTO:patterns/patterns/entity_attribute] synonym: "diameter of ovary" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0001127 ! ovary size trait is_a: PATO:0001334 ! diameter intersection_of: PATO:0001334 ! diameter intersection_of: characteristic_of UBERON:0000992 ! ovary [Term] id: OBA:VT0010454 name: organism trait def: "The quality when measured in multicellular organism." [AUTO:patterns/patterns/attribute_location] synonym: "multicellular organism quality" EXACT [AUTO:patterns/patterns/attribute_location] is_a: PATO:0000001 ! quality intersection_of: PATO:0000001 ! quality intersection_of: characteristic_of UBERON:0000468 ! multicellular organism relationship: characteristic_of UBERON:0000468 ! multicellular organism [Term] id: OBA:VT0010494 name: lumbar vertebra morphology trait def: "The morphology of a lumbar vertebra." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of lumbar vertebra" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000137 ! vertebra morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0002414 ! lumbar vertebra relationship: characteristic_of_part_of UBERON:0002414 ! lumbar vertebra [Term] id: OBA:VT0010508 name: neurocranium mass def: "The mass of a neurocranium." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of neurocranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000429 ! skull quality is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0001703 ! neurocranium relationship: characteristic_of UBERON:0001703 ! neurocranium [Term] id: OBA:VT0010510 name: lumbar vertebra mass def: "The mass of a lumbar vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of lumbar vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0002414 ! lumbar vertebra relationship: characteristic_of UBERON:0002414 ! lumbar vertebra [Term] id: OBA:VT0010517 name: neurocranium size trait def: "The size of a neurocranium." [AUTO:patterns/patterns/entity_attribute] synonym: "size of neurocranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000074 ! neurocranium morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0001703 ! neurocranium relationship: characteristic_of UBERON:0001703 ! neurocranium [Term] id: OBA:VT0010518 name: lumbar vertebra size trait def: "The size of a lumbar vertebra." [AUTO:patterns/patterns/entity_attribute] synonym: "size of lumbar vertebra" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002823 ! vertebra size is_a: OBA:VT0010494 ! lumbar vertebra morphology trait intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0002414 ! lumbar vertebra relationship: characteristic_of UBERON:0002414 ! lumbar vertebra [Term] id: OBA:VT0010612 name: cranium morphology def: "The morphology of a cranium." [obo:oba/patterns/entity_attribute_part_of] synonym: "morphology of cranium" EXACT [obo:oba/patterns/entity_attribute_part_of] is_a: OBA:VT0000438 ! skull morphology trait intersection_of: PATO:0000051 ! morphology intersection_of: characteristic_of_part_of UBERON:0003128 ! cranium relationship: characteristic_of_part_of UBERON:0003128 ! cranium [Term] id: OBA:VT0010613 name: cranium size def: "The size of a cranium." [AUTO:patterns/patterns/entity_attribute] synonym: "size of cranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010612 ! cranium morphology is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0003128 ! cranium relationship: characteristic_of UBERON:0003128 ! cranium [Term] id: OBA:VT0010614 name: cranium mass def: "The mass of a cranium." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of cranium" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000429 ! skull quality is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0003128 ! cranium relationship: characteristic_of UBERON:0003128 ! cranium [Term] id: OBA:VT0015039 name: body width def: "The width of a multicellular organism." [AUTO:patterns/patterns/entity_attribute] synonym: "width of multicellular organism" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100005 ! body size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000468 ! multicellular organism [Term] id: OBA:VT0100000 name: humerus size trait def: "The size of a humerus." [AUTO:patterns/patterns/entity_attribute] synonym: "size of humerus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0005296 ! humerus morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000976 ! humerus relationship: characteristic_of UBERON:0000976 ! humerus [Term] id: OBA:VT0100001 name: tibia size trait def: "The size of a tibia." [AUTO:patterns/patterns/entity_attribute] synonym: "size of tibia" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000558 ! tibia morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000979 ! tibia relationship: characteristic_of UBERON:0000979 ! tibia [Term] id: OBA:VT0100005 name: body size trait def: "The size of a multicellular organism." [AUTO:patterns/patterns/entity_attribute] synonym: "size of multicellular organism" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0010454 ! organism trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000468 ! multicellular organism [Term] id: OBA:VT1000062 name: chest circumference def: "The circumference of a chest." [AUTO:patterns/patterns/entity_attribute] synonym: "chest girth" EXACT [] synonym: "circumference of chest" EXACT [AUTO:patterns/patterns/entity_attribute] synonym: "girth of chest" EXACT [] is_a: OBA:0002620 ! chest size is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0001443 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT1000280 name: humerus width def: "The width of a humerus." [AUTO:patterns/patterns/entity_attribute] synonym: "humerus breadth" EXACT [] synonym: "width of humerus" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100000 ! humerus size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000976 ! humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT1000289 name: tibia width def: "The width of a tibia." [AUTO:patterns/patterns/entity_attribute] synonym: "tibia breadth" EXACT [] synonym: "width of tibia" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0100001 ! tibia size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000979 ! tibia relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT1000361 name: cannon bone circumference def: "The circumference of a metacarpal bone of digit 3." [AUTO:patterns/patterns/entity_attribute] synonym: "circumference of metacarpal bone of digit 3" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002195 ! metacarpal bone size is_a: PATO:0001648 ! circumference intersection_of: PATO:0001648 ! circumference intersection_of: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: characteristic_of UBERON:0003647 ! metacarpal bone of digit 3 [Term] id: OBA:VT1000369 name: femur size trait def: "The size of a femur." [AUTO:patterns/patterns/entity_attribute] synonym: "size of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT0000559 ! femur morphology trait is_a: PATO:0000117 ! size intersection_of: PATO:0000117 ! size intersection_of: characteristic_of UBERON:0000981 ! femur relationship: characteristic_of UBERON:0000981 ! femur [Term] id: OBA:VT1000425 name: skin mass def: "The mass of a zone of skin." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of zone of skin" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0000014 ! zone of skin relationship: characteristic_of UBERON:0000014 ! zone of skin [Term] id: OBA:VT1000641 name: ovary mass def: "The mass of a ovary." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of ovary" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:1000545 ! ovary quality is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0000992 ! ovary relationship: characteristic_of UBERON:0000992 ! ovary [Term] id: OBA:VT1000644 name: testes mass def: "The mass of a testis." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of testis" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0000473 ! testis relationship: characteristic_of UBERON:0000473 ! testis [Term] id: OBA:VT1000666 name: femur width def: "The width of a femur." [AUTO:patterns/patterns/entity_attribute] synonym: "femur breadth" EXACT [] synonym: "width of femur" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:VT1000369 ! femur size trait is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0000981 ! femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: OBA:VT1000687 name: forelimb mass def: "The mass of a forelimb." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of forelimb" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0002102 ! forelimb relationship: characteristic_of UBERON:0002102 ! forelimb [Term] id: OBA:VT1000688 name: metatarsus mass def: "The mass of a metatarsal bone." [AUTO:patterns/patterns/entity_attribute] synonym: "mass of metatarsal bone" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: PATO:0000125 ! mass intersection_of: PATO:0000125 ! mass intersection_of: characteristic_of UBERON:0001448 ! metatarsal bone relationship: characteristic_of UBERON:0001448 ! metatarsal bone [Term] id: OBA:VT1000731 name: chest width def: "The width of a chest." [AUTO:patterns/patterns/entity_attribute] synonym: "width of chest" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002620 ! chest size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: characteristic_of UBERON:0001443 [Term] id: OBA:VT1000732 name: chest depth def: "The depth of a chest." [AUTO:patterns/patterns/entity_attribute] synonym: "depth of chest" EXACT [AUTO:patterns/patterns/entity_attribute] is_a: OBA:0002620 ! chest size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: characteristic_of UBERON:0001443 [Term] id: OBI:0000011 name: planned process def: "A process that realizes a plan which is the concretization of a plan specification." [] is_a: BFO:0000015 ! process is_a: http://rs.tdwg.org/dwc/terms/Event ! Event property_value: editor_note "'Plan' includes a future direction sense. That can be problematic if plans are changed during their execution. There are however implicit contingencies for protocols that an agent has in his mind that can be considered part of the plan, even if the agent didn't have them in mind before. Therefore, a planned process can diverge from what the agent would have said the plan was before executing it, by adjusting to problems encountered during execution (e.g. choosing another reagent with equivalent properties, if the originally planned one has run out.)" xsd:string property_value: editor_note "We are only considering successfully completed planned processes. A plan may be modified, and details added during execution. For a given planned process, the associated realized plan specification is the one encompassing all changes made during execution. This means that all processes in which an agent acts towards achieving some \nobjectives is a planned process." xsd:string property_value: IAO:0000111 "planned process" xsd:string property_value: IAO:0000111 "planned process" xsd:string property_value: IAO:0000112 "Injecting mice with a vaccine in order to test its efficacy" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Bjoern Peters" xsd:string property_value: IAO:0000119 "branch derived" xsd:string property_value: IAO:0000232 "6/11/9: Edited at workshop. Used to include: is initiated by an agent" xsd:string property_value: IAO:0000232 "This class merges the previously separated objective driven process and planned process, as they the separation proved hard to maintain. (1/22/09, branch call)" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl [Term] id: OBI:0000112 name: specimen role def: "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation" [] is_a: BFO:0000023 ! role is_a: CHEBI:50906 ! role property_value: editor_note "22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role." xsd:string property_value: editor_note "blood taken from animal: animal continues in study, whereas blood has role specimen.\nsomething taken from study subject, leaves the study and becomes the specimen." xsd:string property_value: editor_note "Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation." xsd:string property_value: editor_note "parasite example\n- when parasite in people we study people, people are subjects and parasites are specimen\n- when parasite extracted, they become subject in the following study\nspecimen can later be subject." xsd:string property_value: IAO:0000111 "specimen role" xsd:string property_value: IAO:0000112 "liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "GROUP: Role Branch" xsd:string property_value: IAO:0000118 "material sample" xsd:string property_value: IAO:0000119 "OBI" xsd:string [Term] id: OBI:0000245 name: organization def: "An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members." [] is_a: BFO:0000040 ! material entity property_value: editor_note "BP: The definition summarizes long email discussions on the OBI developer, roles, biomaterial and denrie branches. It leaves open if an organization is a material entity or a dependent continuant, as no consensus was reached on that. The current placement as material is therefore temporary, in order to move forward with development. Here is the entire email summary, on which the definition is based:\n\n1) there are organization_member_roles (president, treasurer, branch\neditor), with individual persons as bearers\n\n2) there are organization_roles (employer, owner, vendor, patent holder)\n\n3) an organization has a charter / rules / bylaws, which specify what roles\nthere are, how they should be realized, and how to modify the\ncharter/rules/bylaws themselves.\n\nIt is debatable what the organization itself is (some kind of dependent\ncontinuant or an aggregate of people). This also determines who/what the\nbearer of organization_roles' are. My personal favorite is still to define\norganization as a kind of 'legal entity', but thinking it through leads to\nall kinds of questions that are clearly outside the scope of OBI.\n\nInterestingly enough, it does not seem to matter much where we place\norganization itself, as long as we can subclass it (University, Corporation,\nGovernment Agency, Hospital), instantiate it (Affymetrix, NCBI, NIH, ISO,\nW3C, University of Oklahoma), and have it play roles.\n\nThis leads to my proposal: We define organization through the statements 1 -\n3 above, but without an 'is a' statement for now. We can leave it in its\ncurrent place in the is_a hierarchy (material entity) or move it up to\n'continuant'. We leave further clarifications to BFO, and close this issue\nfor now." xsd:string property_value: IAO:0000111 "organization" xsd:string property_value: IAO:0000112 "PMID: 16353909.AAPS J. 2005 Sep 22;7(2):E274-80. Review. The joint food and agriculture organization of the United Nations/World Health Organization Expert Committee on Food Additives and its role in the evaluation of the safety of veterinary drug residues in foods." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Philippe Rocca-Serra" xsd:string property_value: IAO:0000117 "PERSON: Susanna Sansone" xsd:string property_value: IAO:0000119 "GROUP: OBI" xsd:string [Term] id: OBI:0000659 name: specimen collection process def: "A planned process with the objective of collecting a specimen." [] is_a: OBI:0000011 ! planned process intersection_of: OBI:0000011 ! planned process intersection_of: OBI:0000417 OBI:0000684 ! achieves_planned_objective specimen collection objective relationship: OBI:0000293 BFO:0000040 ! has_specified_input material entity relationship: OBI:0000299 OBI:0100051 ! has_specified_output specimen relationship: OBI:0000417 OBI:0000684 ! achieves_planned_objective specimen collection objective property_value: BCO:0000060 "specimen collection process" xsd:string property_value: editor_note "label changed to 'specimen collection process' on 10/27/2014, details see tracker:\nhttp://sourceforge.net/p/obi/obi-terms/716/" xsd:string property_value: editor_note "Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation." xsd:string property_value: editor_note "Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role." xsd:string property_value: editor_note "Philly2013: The specimen_role for the specimen is created during the specimen collection process." xsd:string property_value: IAO:0000111 "specimen collection process" xsd:string property_value: IAO:0000112 "drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Bjoern Peters" xsd:string property_value: IAO:0000118 "specimen collection" xsd:string property_value: IAO:0000232 "5/31/2012: This process is not necessarily an acquisition, as specimens may be collected from materials already in posession" xsd:string property_value: IAO:0000232 "6/9/09: used at workshop" xsd:string [Term] id: OBI:0000684 name: specimen collection objective def: "A objective specification to obtain a material entity for potential use as an input during an investigation." [] is_a: IAO:0000005 ! objective specification property_value: IAO:0000111 "specimen collection objective" xsd:string property_value: IAO:0000112 "The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Bjoern Peters" xsd:string property_value: IAO:0000119 "Bjoern Peters" xsd:string [Term] id: OBI:0002076 name: collection of specimens def: "A material entity that has two or more specimens as its parts." [] is_a: BFO:0000040 ! material entity intersection_of: BFO:0000040 ! material entity intersection_of: has_member OBI:0100051 {all_only="true"} ! specimen property_value: editor_note "Details see tracker: https://sourceforge.net/p/obi/obi-terms/778/" xsd:string property_value: http://purl.org/dc/elements/1.1/source "Biobank" xsd:string property_value: IAO:0000111 "collection of specimens" xsd:string property_value: IAO:0000112 "Blood cells collected from multiple donors over the course of a study." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Person: Chris Stoeckert, Jie Zheng" xsd:string property_value: IAO:0000119 "OBIB, OBI" xsd:string [Term] id: OBI:0100026 name: organism def: "A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs." [] is_a: BFO:0000040 ! material entity union_of: NCBITaxon:10239 ! Viruses union_of: NCBITaxon:2 ! Bacteria union_of: NCBITaxon:2157 ! Archaea union_of: NCBITaxon:2759 ! Eukaryota property_value: editor_note "10/21/09: This is a placeholder term, that should ideally be imported from the NCBI taxonomy, but the high level hierarchy there does not suit our needs (includes plasmids and 'other organisms')" xsd:string property_value: editor_note "13-02-2009:\nOBI doesn't take position as to when an organism starts or ends being an organism - e.g. sperm, foetus.\nThis issue is outside the scope of OBI." xsd:string property_value: IAO:0000111 "organism" xsd:string property_value: IAO:0000112 "animal" xsd:string property_value: IAO:0000112 "fungus" xsd:string property_value: IAO:0000112 "plant" xsd:string property_value: IAO:0000112 "virus" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "GROUP: OBI Biomaterial Branch" xsd:string property_value: IAO:0000119 "WEB: http://en.wikipedia.org/wiki/Organism" xsd:string [Term] id: OBI:0100051 name: specimen def: "A material entity that has the specimen role." [] is_a: http://rs.tdwg.org/dwc/terms/MaterialSample ! Material Sample intersection_of: BFO:0000040 ! material entity intersection_of: has_role OBI:0000112 ! specimen role equivalent_to: http://rs.tdwg.org/dwc/terms/MaterialSample ! Material Sample property_value: editor_note "Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation." xsd:string property_value: IAO:0000111 "specimen" xsd:string property_value: IAO:0000112 "A herbarium or museum specimen." xsd:string property_value: IAO:0000112 "A jar of water, the microbes that were filtered from that water, the DNA extracted from those microbes, a subsample of that DNA." xsd:string property_value: IAO:0000112 "Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen." xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: James Malone" xsd:string property_value: IAO:0000117 "PERSON: Philippe Rocca-Serra" xsd:string property_value: IAO:0000119 "GROUP: OBI Biomaterial Branch" xsd:string [Term] id: ObsoleteClass name: Obsolete Class [Term] id: PATO:0000001 name: quality namespace: quality alt_id: PATO:0000072 def: "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" [PATOC:GVG] is_a: BFO:0000020 ! specifically dependent continuant [Term] id: PATO:0000025 name: composition namespace: quality alt_id: PATO:0002015 def: "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." [PATOC:GVG] comment: For example calcium composition (which may inhere in bone), haemoglobin composition (which may inhere in blood). subset: attribute_slim subset: scalar_slim synonym: "composed of" EXACT [] synonym: "compositionality" EXACT [] synonym: "content" EXACT [] synonym: "structure, composition" EXACT [] is_a: PATO:0000141 ! structure [Term] id: PATO:0000051 name: morphology namespace: quality def: "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001241 ! physical object quality property_value: IAO:0000111 "morphology" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl [Term] id: PATO:0000052 name: shape namespace: quality alt_id: PATO:0001647 def: "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." [PATOC:GVG] comment: Shapes are invariant on size transformations. Shapes can be subdivided into 2D and 3D shapes, We can also make a distinction between shapes of complete self-connected objects, and shapes of parts of objects. subset: attribute_slim synonym: "relational shape quality" EXACT [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000068 name: qualitative namespace: quality comment: TODO: define this or obsolete it and move children somewhere else. is_a: PATO:0000001 ! quality [Term] id: PATO:0000069 name: deviation (from_normal) namespace: quality def: "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." [PATOC:GVG] subset: attribute_slim is_a: PATO:0000068 ! qualitative [Term] id: PATO:0000117 name: size namespace: quality def: "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." [WordNet:WordNet] subset: attribute_slim subset: scalar_slim is_a: PATO:0000051 ! morphology [Term] id: PATO:0000119 name: height namespace: quality def: "A 1-D extent quality inhering in a bearer by virtue of the bearer's vertical dimension of extension." [PATOC:GVG] subset: attribute_slim subset: scalar_slim is_a: PATO:0001708 ! 1-D extent [Term] id: PATO:0000122 name: length namespace: quality def: "A 1-D extent quality which is equal to the distance between two points." [PATOC:GVG] comment: Length often refers to the longer or longest dimension of an object, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion. subset: attribute_slim subset: mpath_slim subset: scalar_slim is_a: PATO:0001708 ! 1-D extent property_value: IAO:0000111 "length" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl property_value: seeAlso "https://github.com/pato-ontology/pato/issues/337" xsd:string [Term] id: PATO:0000125 name: mass namespace: quality def: "A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter." [PATOC:GVG] comment: For any biological use of PATO, the concept that should be used is 'mass' and not 'weight'. For example, increased weight of an organism. subset: attribute_slim subset: relational_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality [Term] id: PATO:0000128 name: weight namespace: quality def: "A physical quality inhering in a bearer that has mass near a gravitational body. Important usage note: Note that this ontology has a class for a similar concept, mass (PATO:0000125). Mass and weight are not equivalent. For most use cases, the class mass is strongly preferred over weight." [https://en.wikipedia.org/wiki/Mass#Weight_vs._mass, Wikipedia:http\://en.wikipedia.org/wiki/Weight] comment: For any biological use of PATO, the concept that should be used is 'mass' and not 'weight'. For example, increased weight of an organism. subset: attribute_slim subset: scalar_slim is_a: PATO:0001035 ! force [Term] id: PATO:0000136 name: closure namespace: quality def: "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." [PATOC:CJM, PATOC:GVG] subset: attribute_slim is_a: PATO:0000051 ! morphology [Term] id: PATO:0000141 name: structure namespace: quality alt_id: PATO:0001452 def: "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." [PATOC:GVG] subset: attribute_slim synonym: "conformation" BROAD [VT:1000738] synonym: "relational structural quality" EXACT [] is_a: PATO:0000051 ! morphology [Term] id: PATO:0000150 name: texture namespace: quality def: "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." [PATOC:GVG] subset: attribute_slim is_a: PATO:0000051 ! morphology [Term] id: PATO:0000261 name: maturity namespace: quality def: "A quality of a single physical entity which is held by a bearer when the latter exhibits a state of growth, differentiation, or development." [Merriam-Webster:Merriam-Webster] subset: attribute_slim is_a: PATO:0001995 ! organismal quality [Term] id: PATO:0000402 name: branched namespace: quality def: "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." [WordNet:WordNet] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "ramified" EXACT [] synonym: "ramiform" EXACT [] is_a: PATO:0002009 ! branchiness property_value: RO:0002604 PATO:0000414 [Term] id: PATO:0000406 name: curved namespace: quality def: "A curvature quality inhering in a bearer by virtue of the bearer's having or being marked by a curve or smoothly rounded bend." [WordNet:WordNet] subset: cell_quality subset: value_slim synonym: "bowing" NARROW [] synonym: "curled" RELATED [] is_a: PATO:0001591 ! curvature [Term] id: PATO:0000407 name: flat namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature." [web:http\://www.merriam-webster.com/] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "plate-like" RELATED [] is_a: PATO:0002254 ! flattened [Term] id: PATO:0000411 name: circular namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." [thefreedictionary.com:thefreedictionary.com] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "round" RELATED [] synonym: "rounded" RELATED [] is_a: PATO:0000947 ! elliptic [Term] id: PATO:0000461 name: normal namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." [PATOC:GVG] subset: abnormal_slim subset: mpath_slim subset: value_slim synonym: "average" RELATED [] is_a: PATO:0000068 ! qualitative property_value: RO:0002604 PATO:0000460 [Term] id: PATO:0000570 name: increased height namespace: quality def: "A height which is relatively high." [PATOC:GVG] subset: value_slim synonym: "tall" RELATED [] is_a: PATO:0000119 ! height is_a: PATO:0000586 ! increased size intersection_of: PATO:0000119 ! height intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0000569 [Term] id: PATO:0000573 name: increased length namespace: quality def: "A length quality which is relatively large." [PATOC:GVG] subset: value_slim synonym: "long" EXACT [] is_a: PATO:0000122 ! length is_a: PATO:0000586 ! increased size intersection_of: PATO:0000122 ! length intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0000574 [Term] id: PATO:0000582 name: increased weight namespace: quality def: "A weight which is relatively high." [PATOC:GVG] subset: value_slim synonym: "heavy" EXACT [] synonym: "high weight" EXACT [] is_a: PATO:0000128 ! weight is_a: PATO:0002245 ! increased force intersection_of: PATO:0000128 ! weight intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0000583 [Term] id: PATO:0000586 name: increased size namespace: quality alt_id: PATO:0001202 def: "A size quality which is relatively high." [PATOC:GVG] subset: value_slim synonym: "big" RELATED [] synonym: "enlarged" RELATED [] synonym: "expanded" RELATED [] synonym: "great" RELATED [] synonym: "large" RELATED [] is_a: PATO:0000117 ! size is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000117 ! size intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0000587 [Term] id: PATO:0000600 name: increased width namespace: quality def: "A width which is relatively large." [PATOC:GVG] subset: value_slim synonym: "broad" RELATED [] synonym: "wide" RELATED [] synonym: "wide/broad" RELATED [] is_a: PATO:0000586 ! increased size is_a: PATO:0000921 ! width intersection_of: PATO:0000921 ! width intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0000599 [Term] id: PATO:0000608 name: closed namespace: quality def: "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." [answers.com:answers.com] subset: value_slim synonym: "blocked" RELATED [] is_a: PATO:0000136 ! closure disjoint_from: PATO:0000610 ! open property_value: RO:0002604 PATO:0000610 [Term] id: PATO:0000610 name: open namespace: quality def: "A morphological quality inhering in a bearer by virtue of the bearer's affording unobstructed passage or view." [answers.com:answers.com] subset: value_slim is_a: PATO:0000136 ! closure property_value: RO:0002604 PATO:0000608 [Term] id: PATO:0000921 name: width namespace: quality def: "A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite." [PATOC:GVG] comment: Width often refers to the dimension that is greater than the extent in only one of the other two orthogonal dimensions, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion. subset: attribute_slim subset: scalar_slim synonym: "breadth" RELATED [] is_a: OBA:0002830 ! cervical vertebra size is_a: PATO:0001708 ! 1-D extent property_value: seeAlso "https://github.com/pato-ontology/pato/issues/337" xsd:string [Term] id: PATO:0000944 name: sharpness namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's having a sharp or tapered end or point." [PATOC:GVG] subset: attribute_slim subset: cell_quality synonym: "apiculate" EXACT [] is_a: PATO:0000052 ! shape [Term] id: PATO:0000947 name: elliptic namespace: quality def: "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." [PATOC:GVG] subset: cell_quality subset: mpath_slim subset: value_slim synonym: "ellipse-shaped" EXACT [] synonym: "ellipsoid" EXACT [] synonym: "elliptical" EXACT [] synonym: "oval" RELATED [] synonym: "ovoid" RELATED [] is_a: PATO:0002318 ! superelliptic [Term] id: PATO:0000957 name: opacity namespace: quality def: "An optical quality which obtains by virtue of the ability of the bearer to absorb visible light." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001300 ! optical quality [Term] id: PATO:0000963 name: opaque namespace: quality def: "A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy." [PATOC:GVG] subset: mpath_slim subset: value_slim synonym: "clouding" RELATED [] synonym: "cloudy" RELATED [] synonym: "non-transparent" EXACT [] is_a: PATO:0000957 ! opacity property_value: RO:0002604 PATO:0000964 [Term] id: PATO:0000964 name: transparent namespace: quality def: "A optical quality inhering in a bearer by virtue of the bearer's lacking opacity." [PATOC:GVG] subset: mpath_slim subset: value_slim synonym: "clear" EXACT [] synonym: "hyaline" EXACT [] is_a: PATO:0000957 ! opacity property_value: RO:0002604 PATO:0000963 [Term] id: PATO:0000992 name: viscosity namespace: quality def: "A physical quality of a fluid inhering in a bearer by virtue of the bearer's disposition to internal resistance to flow." [PATOC:GVG] subset: attribute_slim subset: disposition_slim is_a: PATO:0001548 ! quality of a liquid [Term] id: PATO:0000998 name: viscous namespace: quality def: "A viscosity quality inhering in a bearer by virtue of the bearer's having viscosity." [PATOC:GVG] subset: disposition_slim subset: mpath_slim subset: value_slim is_a: PATO:0000992 ! viscosity [Term] id: PATO:0001018 name: physical quality namespace: quality alt_id: PATO:0002079 def: "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." [PATOC:GVG] subset: attribute_slim synonym: "relational physical quality" EXACT [] xref: Wikipedia:Physical_property is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0001031 name: elasticity namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster] subset: attribute_slim subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality [Term] id: PATO:0001035 name: force namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's rate of change of momentum." [thesaurus.maths:thesaurus.maths] subset: attribute_slim subset: scalar_slim synonym: "force amplitude" EXACT [] is_a: PATO:0001018 ! physical quality [Term] id: PATO:0001171 name: elastic namespace: quality def: "An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way." [merriam-webster:merriam-webster] subset: disposition_slim subset: mpath_slim subset: value_slim is_a: PATO:0001031 ! elasticity property_value: RO:0002604 PATO:0001172 [Term] id: PATO:0001185 name: larval namespace: quality def: "A maturity quality inhering in a bearer by virtue of the bearer's indirect development, undergoing metamorphosis." [Wikipedia:http\://en.wikipedia.org/wiki/Larval] subset: value_slim is_a: PATO:0000261 ! maturity [Term] id: PATO:0001190 name: juvenile namespace: quality def: "A maturity quality inhering in a bearer by virtue the bearer's being not fully grown or developed." [thefreedictionary.com:thefreedictionary.com] subset: mpath_slim subset: value_slim is_a: PATO:0000261 ! maturity [Term] id: PATO:0001241 name: physical object quality namespace: quality alt_id: PATO:0001237 alt_id: PATO:0001238 def: "A quality which inheres in a continuant." [PATOC:GVG] comment: Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles. synonym: "monadic quality of a continuant" EXACT [] synonym: "monadic quality of an object" NARROW [] synonym: "monadic quality of continuant" NARROW [] synonym: "multiply inhering quality of a physical entity" EXACT [] synonym: "quality of a continuant" EXACT [] synonym: "quality of a single physical entity" EXACT [] synonym: "quality of an object" EXACT [] synonym: "quality of continuant" EXACT [] xref: snap:Quality is_a: BFO:0000019 ! quality is_a: PATO:0000001 ! quality property_value: IAO:0000111 "physical object quality" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/pato.owl [Term] id: PATO:0001292 name: full-spectrum EM radiation quality namespace: quality def: "An EM radiation quality that is independent of the EM wavelength range." [PATOC:GVG] subset: attribute_slim is_a: PATO:0070060 ! quality of interaction of a substance with electromagnetic radiation [Term] id: PATO:0001294 name: radiation reflective quality namespace: quality def: "A scalar EM radiation quality which obtains by the capacity of the bearer to scatter or reflect radiation." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001292 ! full-spectrum EM radiation quality [Term] id: PATO:0001297 name: reflectivity namespace: quality def: "A radiation reflective quality inhering in a bearer by virtue of the ratio of the energy of a wave reflected from its surface to the energy possessed by the wave striking the bearer's surface." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001294 ! radiation reflective quality [Term] id: PATO:0001300 name: optical quality namespace: quality def: "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." [PATOC:GVG] subset: attribute_slim is_a: PATO:0070060 ! quality of interaction of a substance with electromagnetic radiation [Term] id: PATO:0001334 name: diameter namespace: quality def: "A length quality which is equal to the length of any straight line segment that passes through the center of a circle and whose endpoints are on the circular boundary." [Wikipedia:http\://en.wikipedia.org/wiki/Diameter] subset: attribute_slim subset: mpath_slim subset: scalar_slim is_a: PATO:0001708 ! 1-D extent [Term] id: PATO:0001374 name: ploidy namespace: quality def: "A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism." [Wikipedia:http\://en.wikipedia.org/wiki/Ploidy] subset: attribute_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001375 name: haploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Haploid] subset: cell_quality subset: value_slim is_a: PATO:0001393 ! euploid [Term] id: PATO:0001393 name: euploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes." [Wikipedia:http\://en.wikipedia.org/wiki/Euploid] subset: cell_quality subset: value_slim is_a: PATO:0001374 ! ploidy [Term] id: PATO:0001394 name: diploid namespace: quality def: "A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father." [Wikipedia:http\://en.wikipedia.org/wiki/Diploid] comment: The exact number may be one or two different from the 2n number and still be classified as diploidy (although with aneuploidy). Nearly all mammals are diploid organisms, although all individuals have some small fraction of cells that are polyploidy. subset: cell_quality subset: value_slim is_a: PATO:0001393 ! euploid [Term] id: PATO:0001396 name: cellular quality namespace: quality def: "A monadic quality of continuant that exists at the cellular level of organisation." [PATOC:GVG] is_a: PATO:0070044 ! anatomical structure quality [Term] id: PATO:0001397 name: cellular potency namespace: quality def: "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types." [PATOC:GVG] subset: attribute_slim subset: disposition_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001400 name: unipotent namespace: quality def: "A cellular potency that is the capacity to produce only one differentiated cell type." [Wikipedia:http\://en.wikipedia.org/wiki/Unipotent] comment: Unipotent cells have the quality of self-renewal which distinguishes them from non-stem cells. subset: cell_quality subset: disposition_slim subset: value_slim is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001401 name: oligopotent namespace: quality def: "A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity." [PATOC:MAH] comment: Less potent than multipotent, often thought of as precursor or progenitor cell status. subset: cell_quality subset: disposition_slim subset: value_slim is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001402 name: multipotent namespace: quality def: "A cellular potency that is the capacity to form multiple differentiated cell types." [Wikipedia:http\://en.wikipedia.org/wiki/Multipotent] subset: cell_quality subset: disposition_slim subset: value_slim is_a: PATO:0001397 ! cellular potency [Term] id: PATO:0001404 name: nucleate quality namespace: quality def: "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001405 name: anucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001404 ! nucleate quality [Term] id: PATO:0001406 name: binucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001908 ! multinucleate [Term] id: PATO:0001407 name: mononucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001408 name: ciliatedness namespace: quality def: "A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body." [Wikipedia:http\://en.wikipedia.org/wiki/Ciliated] subset: cell_quality subset: value_slim is_a: PATO:0001396 ! cellular quality [Term] id: PATO:0001410 name: striated namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel." [Biology-online:Biology-online] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0001419 name: sharp namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's terminating in a point or edge." [PATOC:GVG] subset: cell_quality subset: value_slim is_a: PATO:0000944 ! sharpness [Term] id: PATO:0001500 name: tapered namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being gradually narrower or thinner toward one end." [WordNet:WordNet] subset: cell_quality subset: value_slim synonym: "taper" EXACT [] is_a: PATO:0001419 ! sharp [Term] id: PATO:0001501 name: immature namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development." [Merriam-Webster:Merriam-Webster] subset: value_slim synonym: "underdeveloped" RELATED [] is_a: PATO:0000261 ! maturity property_value: RO:0002604 PATO:0001701 [Term] id: PATO:0001543 name: flexibility namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's disposition to being turned, bowed, or twisted without breaking." [merriam-webster:merriam-webster] subset: attribute_slim subset: disposition_slim is_a: PATO:0001546 ! quality of a solid [Term] id: PATO:0001544 name: flexible namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's ability of being turned, bowed, or twisted without breaking." [merriam-webster:merriam-webster] subset: disposition_slim subset: value_slim synonym: "bendy" EXACT [] is_a: PATO:0001543 ! flexibility property_value: RO:0002604 PATO:0001545 [Term] id: PATO:0001546 name: quality of a solid namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/soliddefinition.htm] subset: attribute_slim synonym: "solidity" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001547 name: quality of a gas namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape." [Chemistry:http\://chemistry.about.com/od/chemistryglossary/a/gasdefinition.htm, PATOC:GVG] subset: attribute_slim synonym: "gaseous" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001548 name: quality of a liquid namespace: quality def: "A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape." [url:http\://www.chemistry-dictionary.com/definition/liquid.php] subset: attribute_slim synonym: "liquidity" EXACT [] is_a: PATO:0002198 ! quality of a substance [Term] id: PATO:0001563 name: increased mass namespace: quality alt_id: PATO:0000578 def: "A mass which is higher than normal or average." [PATO:GVG] subset: value_slim synonym: "high mass" EXACT [] synonym: "large mass" EXACT [] is_a: PATO:0000125 ! mass is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000125 ! mass intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001562 [Term] id: PATO:0001579 name: contractility namespace: quality def: "A physical quality that is the ability to contract or shrink." [WordNet:WordNet] subset: attribute_slim subset: disposition_slim subset: scalar_slim is_a: PATO:0001018 ! physical quality [Term] id: PATO:0001580 name: increased contractility namespace: quality def: "A contractility which is relatively high." [PATO:GVG] subset: disposition_slim subset: value_slim synonym: "high contractility" EXACT [] is_a: PATO:0001690 ! contractile is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0001690 ! contractile intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001581 [Term] id: PATO:0001591 name: curvature namespace: quality def: "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending." [WordNet:WordNet] subset: attribute_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0001592 name: increased curvature namespace: quality def: "A curvature which is relatively high." [PATO:GVG] subset: value_slim is_a: PATO:0000406 ! curved is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000406 ! curved intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001593 [Term] id: PATO:0001595 name: depth namespace: quality def: "A 1-D extent quality inhering in a bearer by virtue of the bearer's downward or backward or inward dimension." [WordNet:WordNet] subset: attribute_slim subset: scalar_slim is_a: PATO:0001708 ! 1-D extent [Term] id: PATO:0001596 name: increased depth namespace: quality alt_id: PATO:0001666 def: "A depth quality which is relatively high." [PATO:GVG] subset: value_slim synonym: "deep" EXACT [] is_a: PATO:0000586 ! increased size is_a: PATO:0001595 ! depth intersection_of: PATO:0001595 ! depth intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001472 [Term] id: PATO:0001648 name: circumference namespace: quality def: "An 1-D extent quality which is equal to the length of the closed curve of a circle." [WordNet:WordNet] subset: attribute_slim subset: scalar_slim is_a: PATO:0001711 ! perimeter [Term] id: PATO:0001690 name: contractile namespace: quality def: "A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted." [PATOC:GVG] comment: This refers to the disposition of the bearer. subset: disposition_slim subset: value_slim is_a: PATO:0001579 ! contractility property_value: RO:0002604 PATO:0001691 [Term] id: PATO:0001693 name: increased viscosity namespace: quality def: "A viscosity which relatively high." [PATOC:GVG] subset: disposition_slim subset: value_slim synonym: "high viscosity" EXACT [] is_a: PATO:0000998 ! viscous is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0000998 ! viscous intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001694 [Term] id: PATO:0001708 name: 1-D extent namespace: quality def: "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." [PATOC:GVG] subset: attribute_slim synonym: "1-D size" EXACT [] is_a: PATO:0000117 ! size [Term] id: PATO:0001711 name: perimeter namespace: quality def: "An 1-D extent quality inhering in two-dimensional bearer by virtue of being equal to the distance around it." [Wikipedia:http\://en.wikipedia.org/wiki/Perimeter] subset: attribute_slim subset: scalar_slim is_a: PATO:0001708 ! 1-D extent [Term] id: PATO:0001712 name: increased perimeter namespace: quality def: "A perimeter which is relatively high." [PATOC:GVG] subset: value_slim is_a: PATO:0000573 ! increased length is_a: PATO:0001711 ! perimeter intersection_of: PATO:0001711 ! perimeter intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001713 [Term] id: PATO:0001714 name: increased diameter namespace: quality def: "A diameter which is relatively large." [PATOC:GVG] subset: value_slim is_a: PATO:0000586 ! increased size is_a: PATO:0001334 ! diameter intersection_of: PATO:0001334 ! diameter intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001715 [Term] id: PATO:0001735 name: liquid configuration namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids." [PATOC:GVG] synonym: "liquid" EXACT [] is_a: PATO:0001548 ! quality of a liquid [Term] id: PATO:0001736 name: solid configuration namespace: quality def: "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of solids." [PATOC:GVG] subset: value_slim synonym: "solid" EXACT [] is_a: PATO:0001546 ! quality of a solid [Term] id: PATO:0001748 name: invaginated namespace: quality def: "A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave." [PATOC:GVG] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001857 ! concave [Term] id: PATO:0001776 name: increased flexibility namespace: quality def: "A flexibility which is relatively high." [PATOC:GVG] subset: disposition_slim subset: value_slim synonym: "high flexibility" EXACT [] is_a: PATO:0001544 ! flexible is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0001544 ! flexible intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001777 [Term] id: PATO:0001789 name: domed namespace: quality def: "A curvature quality inhering in a bearer by virtue of the bearer's having a shape resembling a dome." [PATOC:GVG] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0000406 ! curved [Term] id: PATO:0001857 name: concave namespace: quality def: "A shape quality in a bearer by virtue of the bearer's curving inward." [WordNet:WordNet] subset: cell_quality subset: value_slim is_a: PATO:0002005 ! concavity property_value: RO:0002604 PATO:0001355 [Term] id: PATO:0001873 name: cylindrical namespace: quality alt_id: PATO:0001203 def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." [PATOC:MAH] subset: cell_quality subset: value_slim synonym: "rod-like" EXACT [] synonym: "rod-shaped" EXACT [] synonym: "tubulate" NARROW [] is_a: PATO:0002007 ! convex 3-D shape relationship: has_cross_section PATO:0000411 ! circular [Term] id: PATO:0001898 name: increased circumference namespace: quality def: "A circumference which is relatively high." [PATOC:GVG] subset: value_slim is_a: PATO:0001648 ! circumference is_a: PATO:0001712 ! increased perimeter intersection_of: PATO:0001648 ! circumference intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0001899 [Term] id: PATO:0001908 name: multinucleate namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0002505 ! nucleated [Term] id: PATO:0001973 name: cuspidate namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being tapering gradually into a rigid point." [ISBN:0881923214] subset: value_slim is_a: PATO:0001500 ! tapered [Term] id: PATO:0001987 name: saccular namespace: quality def: "A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance." [PATOC:MAH] subset: value_slim synonym: "sacular" EXACT [] is_a: PATO:0002014 ! structure, cavities [Term] id: PATO:0001992 name: cellularity namespace: quality def: "An organismal quality inhering in a bearer by virtue of the bearer's consisting cells." [PATOC:GVG] subset: attribute_slim subset: scalar_slim is_a: PATO:0001995 ! organismal quality [Term] id: PATO:0001993 name: multicellular namespace: quality def: "A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell." [PATOC:GVG] subset: value_slim is_a: PATO:0001992 ! cellularity [Term] id: PATO:0001995 name: organismal quality namespace: quality def: "A quality that inheres in an entire organism or part of an organism." [PATOC:CJM] is_a: PATO:0001241 ! physical object quality [Term] id: PATO:0002005 name: concavity namespace: quality def: "Surface shape that refers to the inward or outward curvature of the surface." [PATOC:MAH] subset: attribute_slim is_a: PATO:0000052 ! shape [Term] id: PATO:0002006 name: 2-D shape namespace: quality def: "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." [PATOC:CJM] subset: attribute_slim synonym: "2-D projection" RELATED [] synonym: "cross-sectional" RELATED [] is_a: PATO:0000052 ! shape [Term] id: PATO:0002007 name: convex 3-D shape namespace: quality def: "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." [PATOC:CJM] comment: Use this term or an is_a child of this term when the entire shape of the object is known. subset: attribute_slim xref: Image:http\://upload.wikimedia.org/wikipedia/commons/0/06/Convex_polygon_illustration1.png is_a: PATO:0002266 ! 3-D shape relationship: has_cross_section PATO:0002006 ! 2-D shape property_value: RO:0002604 PATO:0002008 [Term] id: PATO:0002009 name: branchiness namespace: quality def: "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." [PATOC:MAH] subset: attribute_slim subset: cell_quality is_a: PATO:0000052 ! shape [Term] id: PATO:0002014 name: structure, cavities namespace: quality def: "A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas." [PATOC:GVG] subset: attribute_slim is_a: PATO:0000141 ! structure [Term] id: PATO:0002039 name: biconcave namespace: quality def: "A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces." [PATOC:GVG] subset: value_slim is_a: PATO:0001857 ! concave property_value: RO:0002604 PATO:0002040 [Term] id: PATO:0002045 name: dendritic namespace: quality def: "A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure." [PATOC:cvs] subset: value_slim synonym: "dendriform" EXACT [] synonym: "dendroid" EXACT [] synonym: "dendroidal" EXACT [] is_a: PATO:0000402 ! branched relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-02-15T08:11:41Z [Term] id: PATO:0002078 name: hollow namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within." [url:http\://www.merriam-webster.com/dictionary/hollow] subset: value_slim is_a: PATO:0002014 ! structure, cavities relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-09-18T02:19:20Z [Term] id: PATO:0002094 name: basophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions." [PATOC:GVG] subset: disposition_slim subset: mpath_slim subset: value_slim is_a: PATO:0070045 ! anatomical histological quality relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-10-05T12:05:23Z [Term] id: PATO:0002124 name: laminar namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0000141 ! structure relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2009-10-06T04:37:14Z [Term] id: PATO:0002198 name: quality of a substance namespace: quality def: "A quality inhering in a bearer by virtue of its constitution." [PATOC:GVG] subset: attribute_slim is_a: PATO:0001018 ! physical quality relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-03-15T04:35:27Z [Term] id: PATO:0002226 name: subcylindrical namespace: quality def: "A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical." [url:http\://www.thefreedictionary.com/Subcylindrical] subset: value_slim is_a: PATO:0001873 ! cylindrical relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-07-13T04:22:30Z [Term] id: PATO:0002245 name: increased force namespace: quality def: "A force which relative high." [PATOC:GVG] subset: value_slim synonym: "increased force amplitude" EXACT [] is_a: PATO:0001035 ! force is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0001035 ! force intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal relationship: dc-contributor https://orcid.org/0000-0002-2061-091X property_value: RO:0002604 PATO:0002246 creation_date: 2010-08-04T11:12:20Z [Term] id: PATO:0002254 name: flattened namespace: quality def: "A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane." [PATOC:CVS] comment: Becoming flat but not necessarily completely flat. subset: value_slim synonym: "compressed" RELATED [] is_a: PATO:0001591 ! curvature relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-08-16T03:59:34Z [Term] id: PATO:0002255 name: grooved namespace: quality def: "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." [PATOC:JE] subset: value_slim synonym: "channeled" RELATED [] synonym: "creased" RELATED [] is_a: PATO:0000150 ! texture relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-09-01T10:27:48Z [Term] id: PATO:0002266 name: 3-D shape namespace: quality def: "A shape that inheres in a 3 dimensional entity." [PATOC:OREGON] is_a: PATO:0000052 ! shape relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2010-10-05T12:31:16Z [Term] id: PATO:0002287 name: increased elasticity namespace: quality def: "An elasticity which is relatively high." [PATOC:GVG] subset: value_slim is_a: PATO:0001171 ! elastic is_a: PATO:0002305 ! increased object quality intersection_of: PATO:0001171 ! elastic intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal relationship: dc-contributor https://orcid.org/0000-0002-2061-091X property_value: RO:0002604 PATO:0002288 creation_date: 2011-03-30T11:50:21Z [Term] id: PATO:0002299 name: tubular namespace: quality def: "A cylindrical shape that is hollow." [PATOC:GVG] synonym: "tube like" EXACT [] synonym: "tube-shaped" EXACT [] synonym: "tubulate" EXACT [] is_a: PATO:0001873 ! cylindrical is_a: PATO:0002078 ! hollow relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-06-08T06:33:50Z [Term] id: PATO:0002300 name: increased quality namespace: quality def: "A quality that has a value that is increased compared to normal or average." [PATOC:GVG] is_a: PATO:0000069 ! deviation (from_normal) intersection_of: PATO:0000001 ! quality intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal relationship: dc-contributor https://orcid.org/0000-0002-2061-091X relationship: increased_in_magnitude_relative_to PATO:0000461 ! normal property_value: RO:0002604 PATO:0002301 creation_date: 2011-06-16T06:39:43Z [Term] id: PATO:0002305 name: increased object quality namespace: quality def: "A quality of an object that has a value that is increased compared to normal or average." [PATOC:GVG] is_a: PATO:0001241 ! physical object quality is_a: PATO:0002300 ! increased quality intersection_of: PATO:0001241 ! physical object quality intersection_of: increased_in_magnitude_relative_to PATO:0000461 ! normal relationship: dc-contributor https://orcid.org/0000-0002-2061-091X property_value: RO:0002604 PATO:0002303 creation_date: 2011-06-16T06:54:01Z [Term] id: PATO:0002309 name: fiber shaped namespace: quality def: "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter." [PATOC:DC] comment: Note that a fiber shaped object may take any circuitous or straight path through space (think of a length of string or rope). subset: value_slim is_a: PATO:0002226 ! subcylindrical relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-09-09T04:50:10Z [Term] id: PATO:0002318 name: superelliptic namespace: quality def: "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" [wiktionary:superellipse] synonym: "Lamé curve" EXACT [] is_a: PATO:0002006 ! 2-D shape relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2011-10-12T12:45:16Z [Term] id: PATO:0002418 name: acidophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions." [PATOC:GVG] comment: Eosin stains acidophilic structures, hence eosinophilic is the same as acidophilic. subset: mpath_slim subset: value_slim synonym: "eosinophilic" EXACT [] is_a: PATO:0070045 ! anatomical histological quality relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2012-12-17T03:01:19Z [Term] id: PATO:0002422 name: acinar namespace: quality def: "Pertaining to the individual parts making up an aggregate fruit like a many-lobed \"berry,\" such as a raspberry." [wikipedia:https\://en.wikipedia.org/wiki/Acinus] comment: Acinus is Latin for berry. subset: mpath_slim subset: value_slim is_a: PATO:0000141 ! structure relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2012-12-17T03:11:10Z [Term] id: PATO:0002444 name: mineralized namespace: quality def: "A composition quality inhering in a bearer by virtue of the bearer's being composed of or possessing inorganic material." [PATOC:WC] subset: value_slim is_a: PATO:0000025 ! composition relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-01-29T11:03:49Z [Term] id: PATO:0002462 name: collagenous namespace: quality def: "A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen." [PATOC:WD] subset: value_slim is_a: PATO:0000025 ! composition relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-09-15T11:34:15Z [Term] id: PATO:0002468 name: distensible namespace: quality def: "A structure quality inhering in a bearer by virtue of the bearer's being capable of swelling or stretching." [PATOC:WD] subset: value_slim is_a: PATO:0015008 ! distensibility relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-09-15T11:48:26Z [Term] id: PATO:0002478 name: transversely striated namespace: quality def: "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer." [PATOC:DS] subset: cell_quality subset: mpath_slim subset: value_slim is_a: PATO:0001410 ! striated relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-09-15T12:29:15Z [Term] id: PATO:0002505 name: nucleated namespace: quality def: "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus." [PATOC:GVG] subset: mpath_slim subset: value_slim is_a: PATO:0001404 ! nucleate quality relationship: dc-contributor https://orcid.org/0000-0002-2061-091X creation_date: 2013-10-21T05:44:34Z [Term] id: PATO:0002507 name: keratinous namespace: quality def: "A composition quality inhering in a bearer by virtue of the bearer's consisting of keratin." [PATOC:EJS] subset: value_slim is_a: PATO:0000025 ! composition relationship: dc-contributor https://orcid.org/0000-0002-9611-1279 creation_date: 2014-02-04T12:38:14Z [Term] id: PATO:0005021 name: unicuspidate namespace: quality def: "Cuspidate quality inhering in a bearer by virtue of the bearer's possessing a single cusp." [PATOC:WD] subset: value_slim is_a: PATO:0001973 ! cuspidate relationship: dc-contributor https://orcid.org/0000-0003-3162-7490 creation_date: 2014-10-17T14:14:04Z [Term] id: PATO:0010001 name: disconnected namespace: quality def: "A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other." [GOC:dos] is_a: PATO:0000141 ! structure relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2014-12-12T08:43:17Z [Term] id: PATO:0015006 name: polymeric namespace: quality def: "A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array." [GOC:DOS, https://github.com/pato-ontology/pato/issues/78] comment: A complete coverage of this domain would subclasses homopolymeric, copolymeric, crystalline. subset: value_slim is_a: PATO:0000141 ! structure [Term] id: PATO:0015008 name: distensibility namespace: quality def: "A quality inhering in a bearer by virtue of the extent to which the bearer is capable of being stretched or swollen." [GOC:CJM] subset: attribute_slim is_a: PATO:0000141 ! structure [Term] id: PATO:0070044 name: anatomical structure quality namespace: quality def: "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components." [] is_a: PATO:0001241 ! physical object quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070045 name: anatomical histological quality namespace: quality def: "A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes." [] is_a: PATO:0070044 ! anatomical structure quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070046 name: neutrophillic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain." [GOC:add] is_a: PATO:0070045 ! anatomical histological quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070047 name: polychromatophilic namespace: quality def: "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions." [GOC:add] is_a: PATO:0070045 ! anatomical histological quality created_by: http://orcid.org/0000-0001-7258-9596 [Term] id: PATO:0070060 name: quality of interaction of a substance with electromagnetic radiation namespace: quality def: "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength." [https://orcid.org/0000-0002-5111-7263] subset: attribute_slim is_a: PATO:0002198 ! quality of a substance [Term] id: PR:000000001 name: protein namespace: protein def: "An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof." [PRO:DAN, PRO:WCB] comment: The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB]. synonym: "native protein" NARROW [IEDB:BP] synonym: "natural protein" EXACT [PRO:DAN] is_a: CHEBI:36080 ! protein intersection_of: PR:000018263 ! amino acid chain intersection_of: has_gene_template SO:0000704 intersection_of: output_of GO:0006412 ! translation [Term] id: PR:000001002 name: CD19 molecule namespace: protein def: "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction." [PMID:15778510] comment: Category=gene. Requested by=CL. synonym: "B-lymphocyte surface antigen B4" EXACT [] synonym: "CD19" EXACT PRO-short-label [PRO:DNx] synonym: "differentiation antigen CD19" EXACT [] synonym: "T-cell surface antigen Leu-12" EXACT [] xref: IUPHARobj:2764 xref: PIRSF:PIRSF016630 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001003 name: CD34 molecule namespace: protein def: "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved." [PMID:16720896, PMID:8983065] comment: Category=gene. Requested by=CL. synonym: "CD34" EXACT PRO-short-label [PRO:DNx] synonym: "hematopoietic progenitor cell antigen CD34" EXACT [] xref: PIRSF:PIRSF028749 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001004 name: CD4 molecule namespace: protein def: "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence." [PMID:15326605] comment: Category=gene. Requested by=CL. synonym: "CD4" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell differentiation antigen L3T4" EXACT [] synonym: "T-cell surface antigen T4/Leu-3" EXACT [] synonym: "T-cell surface glycoprotein CD4" EXACT [] xref: PIRSF:PIRSF001977 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001005 name: integrin alpha with A domain namespace: protein def: "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage." [PIRSF:PIRSF002497] comment: Category=family. synonym: "integrin alpha with I domain" EXACT [] xref: PIRSF:PIRSF002497 is_a: PR:000025796 ! integrin alpha [Term] id: PR:000001012 name: integrin alpha-M namespace: protein def: "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1." [UniProtKB:P11215] comment: Category=gene. Requested by=CL. synonym: "CD11 antigen-like family member B" EXACT [] synonym: "CD11B" RELATED Gene-based [] synonym: "CD11b" EXACT [] synonym: "cell surface glycoprotein MAC-1 subunit alpha" EXACT [] synonym: "CR-3 alpha chain" EXACT [] synonym: "CR3A" RELATED Gene-based [] synonym: "ITGAM" EXACT PRO-short-label [PRO:DNx] synonym: "leukocyte adhesion receptor MO1" EXACT [] synonym: "neutrophil adherence receptor" EXACT [] xref: IUPHARobj:2452 is_a: PR:000001005 ! integrin alpha with A domain [Term] id: PR:000001018 name: CD3 subunit with immunoglobulin domain namespace: protein def: "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response." [PMID:16473826, PMID:1724736] comment: Category=family. synonym: "CD3 subunit with Ig-like domain" EXACT [] xref: PIRSF:PIRSF001993 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001020 name: CD3 epsilon namespace: protein def: "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "CD3E" EXACT PRO-short-label [PRO:DNx] synonym: "CD3e" EXACT [] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain" EXACT [] synonym: "T3E" RELATED Gene-based [] xref: IUPHARobj:2742 is_a: PR:000001018 ! CD3 subunit with immunoglobulin domain [Term] id: PR:000001022 name: neural cell adhesion molecule namespace: protein def: "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF002507 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001023 name: neural cell adhesion molecule NCAM namespace: protein def: "A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration." [PMID:17975827] comment: Category=family. xref: PIRSF:PIRSF501037 is_a: PR:000001022 ! neural cell adhesion molecule [Term] id: PR:000001024 name: neural cell adhesion molecule 1 namespace: protein def: "A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "CD56" EXACT [] synonym: "N-CAM-1" EXACT [] synonym: "NCAM" RELATED Gene-based [] synonym: "NCAM-1" EXACT [] synonym: "NCAM1" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:2769 is_a: PR:000001023 ! neural cell adhesion molecule NCAM [Term] id: PR:000001083 name: CD2 molecule namespace: protein def: "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "CD2" EXACT PRO-short-label [PRO:DNx] synonym: "erythrocyte receptor" EXACT [] synonym: "LFA-2" EXACT [] synonym: "LFA-3 receptor" EXACT [] synonym: "ly-37" EXACT [] synonym: "lymphocyte antigen 37" EXACT [] synonym: "rosette receptor" EXACT [] synonym: "SRBC" RELATED Gene-based [] synonym: "T-cell surface antigen CD2" EXACT [] synonym: "T-cell surface antigen T11/Leu-5" EXACT [] synonym: "T-cell surface glycoprotein CD2" EXACT [] xref: IUPHARobj:2600 xref: PIRSF:PIRSF001984 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001084 name: T-cell surface glycoprotein CD8 alpha chain namespace: protein def: "A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain." [PMID:11114424, PRO:CNA, Wikipedia:CD8] comment: Category=gene. Requested by=CL. synonym: "CD8A" EXACT PRO-short-label [PRO:DNx] synonym: "CD8a" EXACT [] synonym: "Lyt-2" RELATED Gene-based [] synonym: "Lyt2" RELATED Gene-based [] synonym: "MAL" RELATED Gene-based [] synonym: "T-cell surface glycoprotein Lyt-2" EXACT [] synonym: "T-lymphocyte differentiation antigen T8/Leu-2" EXACT [] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001289 name: membrane-spanning 4-domains subfamily A member 1 namespace: protein def: "A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "B-cell differentiation antigen Ly-44" EXACT [] synonym: "B-cell surface antigen CD20" EXACT [] synonym: "B-lymphocyte antigen CD20" EXACT [] synonym: "B-lymphocyte surface antigen B1" EXACT [] synonym: "Bp35" EXACT [] synonym: "CD20" RELATED Gene-based [] synonym: "leukocyte surface antigen Leu-16" EXACT [] synonym: "Ly-44" RELATED Gene-based [] synonym: "lymphocyte antigen 44" EXACT [] synonym: "MS4A1" EXACT PRO-short-label [PRO:DNx] synonym: "Ms4a2" RELATED Gene-based [] xref: IUPHARobj:2628 xref: PIRSF:PIRSF001995 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001327 name: cadherin namespace: protein def: "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF002504 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001444 name: cadherin-5 namespace: protein def: "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "7B4 antigen" EXACT [] synonym: "CD144" EXACT [] synonym: "CDH5" EXACT PRO-short-label [PRO:DNx] synonym: "vascular endothelial cadherin" EXACT [] synonym: "VE-cadherin" EXACT [] is_a: PR:000001327 ! cadherin [Term] id: PR:000001839 name: T-cell surface glycoprotein CD5 namespace: protein def: "A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD5" EXACT PRO-short-label [PRO:DNx] synonym: "LEU1" RELATED Gene-based [] synonym: "ly-1" EXACT [] synonym: "lymphocyte antigen 1" EXACT [] synonym: "lymphocyte antigen T1/Leu-1" EXACT [] synonym: "Lyt-1" EXACT [] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001869 name: interleukin-7 receptor subunit alpha namespace: protein def: "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD127" EXACT [] synonym: "CDw127" EXACT [] synonym: "IL-7 receptor subunit alpha" EXACT [] synonym: "IL-7R subunit alpha" EXACT [] synonym: "IL-7R-alpha" EXACT [] synonym: "IL-7RA" EXACT [] synonym: "IL7R" EXACT PRO-short-label [PRO:DNx] xref: IUPHARobj:1698 xref: PIRSF:PIRSF001960 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001889 name: CD14 molecule namespace: protein def: "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD14" EXACT PRO-short-label [PRO:DNx] synonym: "monocyte differentiation antigen CD14" EXACT [] synonym: "myeloid cell-specific leucine-rich glycoprotein" EXACT [] xref: PIRSF:PIRSF002017 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001945 name: transferrin receptor protein 1 namespace: protein def: "A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD71" EXACT [] synonym: "p90" BROAD [PRO:DNx] synonym: "T9" EXACT [] synonym: "TfR" EXACT [] synonym: "TfR1" EXACT [] synonym: "TFRC" EXACT PRO-short-label [PRO:DNx] synonym: "TR" RELATED [] synonym: "Trfr" RELATED Gene-based [] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000001971 name: vascular endothelial growth factor receptor namespace: protein def: "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain." [PRO:WCB] comment: Category=family. xref: PIRSF:PIRSF038502 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000002112 name: vascular endothelial growth factor receptor 2 namespace: protein def: "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof." [PRO:WCB] comment: Category=gene. Requested by=CL. synonym: "CD309" EXACT [] synonym: "fetal liver kinase 1" EXACT [] synonym: "FLK-1" EXACT [] synonym: "FLK1" RELATED Gene-based [] synonym: "KDR" EXACT PRO-short-label [PRO:DNx] synonym: "kinase insert domain receptor" EXACT [] synonym: "kinase NYK" EXACT [] synonym: "protein-tyrosine kinase receptor flk-1" EXACT [] synonym: "VEGFR-2" EXACT [] synonym: "VEGFR2" RELATED Gene-based [] xref: IUPHARobj:1813 is_a: PR:000001971 ! vascular endothelial growth factor receptor [Term] id: PR:000002976 name: Ly-6-like protein namespace: protein def: "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I)." [PRO:CNA] comment: Category=family. xref: PIRSF:PIRSF002021 is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000002978 name: lymphocyte antigen 6G namespace: protein def: "An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. Requested by=CL. synonym: "Ly-6G" EXACT [] synonym: "Ly-6G.1" EXACT [] synonym: "Ly6g" EXACT PRO-short-label [PRO:DNx] is_a: PR:000002976 ! Ly-6-like protein [Term] id: PR:000002981 name: lymphocyte antigen 76 (mouse) namespace: protein def: "A protein that is a translation product of the Ly76 gene in mouse." [PMID:10848813, PRO:DAN] comment: Category=organism-gene. Requested by=CL. synonym: "mLy76" EXACT PRO-short-label [PRO:DNx] synonym: "ter-119" EXACT [] synonym: "ter119" EXACT [] is_a: PR:000029032 ! Mus musculus protein [Term] id: PR:000007499 name: fibroblast growth factor 8 namespace: protein def: "A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "AIGF" RELATED Gene-based [] synonym: "androgen-induced growth factor" EXACT [] synonym: "FGF-8" EXACT [] synonym: "FGF8" EXACT PRO-short-label [PRO:DNx] synonym: "HBGF-8" RELATED [] synonym: "heparin-binding growth factor 8" RELATED [] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000009054 name: insulin gene translation product namespace: protein def: "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "INS" EXACT PRO-short-label [PRO:DNx] synonym: "insulin" BROAD [PRO:DAN] is_a: PR:000045358 ! insulin family protein [Term] id: PR:000014841 name: sonic hedgehog protein namespace: protein def: "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "HHG-1" EXACT [] synonym: "Hhg1" RELATED Gene-based [] synonym: "SHH" EXACT PRO-short-label [PRO:DNx] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains" EXACT [] synonym: "ShhNC" EXACT [] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000016043 name: T-cell acute lymphocytic leukemia protein 1 namespace: protein def: "A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. Requested by=CL. synonym: "BHLHA17" RELATED Gene-based [] synonym: "bHLHa17" EXACT [] synonym: "class A basic helix-loop-helix protein 17" EXACT [] synonym: "SCL" RELATED Gene-based [] synonym: "stem cell protein" EXACT [] synonym: "T-cell leukemia/lymphoma protein 5" EXACT [] synonym: "TAL-1" EXACT [] synonym: "TAL1" EXACT PRO-short-label [PRO:DNx] synonym: "TCL5" RELATED Gene-based [] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000018263 name: amino acid chain namespace: protein def: "An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds." [PRO:DAN, PRO:JSG] comment: Category=polymer. synonym: "peptide" NARROW [PRO:DAN] synonym: "polypeptide" NARROW [PRO:DAN] is_a: CHEBI:50047 ! organic amino compound relationship: has_constituent_monomer CHEBI:33708 {minCardinality="2"} ! amino-acid residue [Term] id: PR:000025796 name: integrin alpha namespace: protein def: "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif." [PMID:19693543] comment: Category=family. Integrins are heterodimeric complexes of an alpha and a beta subunit. They are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis. [PMID:10402956, PMID:11988479, PMID:9676575]. is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000029032 name: Mus musculus protein namespace: protein def: "A protein that is encoded in the genome of Mus musculus." [PRO:DAN] synonym: "mouse protein" EXACT PRO-short-label [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000029067 name: Homo sapiens protein namespace: protein def: "A protein that is encoded in the genome of Homo sapiens." [PRO:DAN] synonym: "human protein" EXACT PRO-short-label [PRO:DAN] is_a: PR:000036194 ! eukaryotic protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000036194 name: eukaryotic protein namespace: protein def: "A protein that is encoded in the genome of some Eukaryota." [PRO:DAN] synonym: "Eukaryota protein" EXACT [PRO:DAN] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein intersection_of: PR:000000001 ! protein intersection_of: only_in_taxon NCBITaxon:2759 ! Eukaryota relationship: only_in_taxon NCBITaxon:2759 ! Eukaryota [Term] id: PR:000045358 name: insulin family protein namespace: protein def: "A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide." [PRO:DAN] comment: Category=family. synonym: "fam:INS" EXACT PRO-short-label [PRO:DAN] is_a: CHEBI:36080 ! protein is_a: PR:000000001 ! protein [Term] id: PR:000050567 name: protein-containing material entity namespace: protein def: "A material entity that minimally consists of a protein." [PRO:DAN] comment: Note: This includes single proteins and derivatives thereof (PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566). synonym: "protein" NARROW [PRO:DAN] synonym: "protein aggregate" NARROW [PRO:DAN] synonym: "protein complex" NARROW [PRO:DAN] synonym: "protein-containing complex" NARROW [PRO:DAN] is_a: BFO:0000040 ! material entity intersection_of: BFO:0000040 ! material entity intersection_of: has_part PR:000000001 ! protein relationship: has_part PR:000000001 ! protein [Term] id: PR:P01308 name: insulin gene translation product (human) namespace: protein def: "An insulin gene translation product that is encoded in the genome of human." [PRO:DAN, UniProtKB:P01308] comment: Category=organism-gene. synonym: "hINS" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P01308 is_a: PR:000009054 ! insulin gene translation product is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000009054 ! insulin gene translation product intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01730 name: T-cell surface glycoprotein CD4 (human) namespace: protein def: "A CD4 molecule that is encoded in the genome of human." [PRO:DNx, UniProtKB:P01730] comment: Category=organism-gene. synonym: "CD4" RELATED Gene-based [UniProtKB:P01730] synonym: "hCD4" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T4/Leu-3 (human)" EXACT [UniProtKB:P01730] xref: UniProtKB:P01730 is_a: PR:000001004 ! CD4 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001004 ! CD4 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P01731 name: T-cell surface glycoprotein CD8 alpha chain (mouse) namespace: protein def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse." [OMA:P01731, PRO:DNx] comment: Category=organism-gene. synonym: "Cd8a" RELATED Gene-based [UniProtKB:P01731] synonym: "CD8a (mouse)" EXACT [UniProtKB:P01731] synonym: "Lyt-2" RELATED Gene-based [UniProtKB:P01731] synonym: "Lyt2" RELATED Gene-based [UniProtKB:P01731] synonym: "mCD8A" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface glycoprotein Lyt-2 (mouse)" EXACT [UniProtKB:P01731] xref: UniProtKB:P01731 is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P01732 name: T-cell surface glycoprotein CD8 alpha chain (human) namespace: protein def: "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01732] comment: Category=organism-gene. synonym: "CD8A" RELATED Gene-based [UniProtKB:P01732] synonym: "CD8a (human)" EXACT [UniProtKB:P01732] synonym: "hCD8A" EXACT PRO-short-label [PRO:DNx] synonym: "MAL" RELATED Gene-based [UniProtKB:P01732] synonym: "T-lymphocyte differentiation antigen T8/Leu-2 (human)" EXACT [UniProtKB:P01732] xref: UniProtKB:P01732 is_a: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001084 ! T-cell surface glycoprotein CD8 alpha chain intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P02786 name: transferrin receptor protein 1 (human) namespace: protein def: "A transferrin receptor protein 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P02786] comment: Category=organism-gene. synonym: "CD71 (human)" EXACT [UniProtKB:P02786] synonym: "hTFRC" EXACT PRO-short-label [PRO:DNx] synonym: "p90 (human)" BROAD [UniProtKB:P02786] synonym: "T9 (human)" EXACT [UniProtKB:P02786] synonym: "TfR (human)" EXACT [UniProtKB:P02786] synonym: "TfR1 (human)" EXACT [UniProtKB:P02786] synonym: "TFRC" RELATED Gene-based [UniProtKB:P02786] synonym: "TR (human)" BROAD [UniProtKB:P02786] synonym: "Trfr (human)" EXACT [UniProtKB:P02786] xref: Reactome:R-HSA-434196 "PR:P02786 located_in GO:0030659" xref: Reactome:R-HSA-434330 "PR:P02786 located_in GO:0000139" xref: Reactome:R-HSA-8869124 "PR:P02786 located_in GO:0030665" xref: Reactome:R-HSA-8961829 "PR:P02786 located_in GO:0010008" xref: Reactome:R-HSA-917983 "PR:P02786 located_in GO:0005886" xref: UniProtKB:P02786 is_a: PR:000001945 ! transferrin receptor protein 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001945 ! transferrin receptor protein 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P05555 name: integrin alpha-M (mouse) namespace: protein def: "An integrin alpha-M that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P05555] comment: Category=organism-gene. synonym: "CD11 antigen-like family member B (mouse)" EXACT [UniProtKB:P05555] synonym: "CD11b (mouse)" EXACT [UniProtKB:P05555] synonym: "cell surface glycoprotein MAC-1 subunit alpha (mouse)" EXACT [UniProtKB:P05555] synonym: "CR-3 alpha chain (mouse)" EXACT [UniProtKB:P05555] synonym: "Itgam" RELATED Gene-based [UniProtKB:P05555] synonym: "leukocyte adhesion receptor MO1 (mouse)" EXACT [UniProtKB:P05555] synonym: "mITGAM" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P05555 is_a: PR:000001012 ! integrin alpha-M is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001012 ! integrin alpha-M intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P06127 name: T-cell surface glycoprotein CD5 (human) namespace: protein def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P06127] comment: Category=organism-gene. synonym: "CD5" RELATED Gene-based [UniProtKB:P06127] synonym: "hCD5" EXACT PRO-short-label [PRO:DNx] synonym: "LEU1" RELATED Gene-based [UniProtKB:P06127] synonym: "lymphocyte antigen T1/Leu-1 (human)" EXACT [UniProtKB:P06127] xref: UniProtKB:P06127 is_a: PR:000001839 ! T-cell surface glycoprotein CD5 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P06332 name: T-cell surface glycoprotein CD4 (mouse) namespace: protein def: "A CD4 molecule that is encoded in the genome of mouse." [OMA:P06332, PRO:DNx] comment: Category=organism-gene. synonym: "Cd4" RELATED Gene-based [UniProtKB:P06332] synonym: "CD4 (mouse)" EXACT [UniProtKB:P06332] synonym: "mCD4" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell differentiation antigen L3T4 (mouse)" EXACT [UniProtKB:P06332] synonym: "T-cell surface antigen T4/Leu-3 (mouse)" EXACT [UniProtKB:P06332] xref: UniProtKB:P06332 is_a: PR:000001004 ! CD4 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001004 ! CD4 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P06729 name: T-cell surface antigen CD2 (human) namespace: protein def: "A CD2 molecule that is encoded in the genome of human." [PRO:CNA, UniProtKB:P06729] comment: Category=organism-gene. synonym: "CD2" RELATED Gene-based [UniProtKB:P06729] synonym: "erythrocyte receptor (human)" EXACT [UniProtKB:P06729] synonym: "hCD2" EXACT PRO-short-label [PRO:DNx] synonym: "LFA-2 (human)" EXACT [UniProtKB:P06729] synonym: "LFA-3 receptor (human)" EXACT [UniProtKB:P06729] synonym: "rosette receptor (human)" EXACT [UniProtKB:P06729] synonym: "SRBC" RELATED Gene-based [UniProtKB:P06729] synonym: "T-cell surface antigen T11/Leu-5 (human)" EXACT [UniProtKB:P06729] xref: UniProtKB:P06729 is_a: PR:000001083 ! CD2 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001083 ! CD2 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P07766 name: T-cell surface glycoprotein CD3 epsilon chain (human) namespace: protein def: "A CD3 epsilon that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07766] comment: Category=organism-gene. synonym: "CD3E" RELATED Gene-based [UniProtKB:P07766] synonym: "CD3e (human)" EXACT [UniProtKB:P07766] synonym: "hCD3E" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (human)" EXACT [UniProtKB:P07766] synonym: "T3E" RELATED Gene-based [UniProtKB:P07766] xref: UniProtKB:P07766 is_a: PR:000001020 ! CD3 epsilon is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001020 ! CD3 epsilon intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08571 name: monocyte differentiation antigen CD14 (human) namespace: protein def: "A CD14 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P08571] comment: Category=organism-gene. synonym: "CD14" RELATED Gene-based [UniProtKB:P08571] synonym: "hCD14" EXACT PRO-short-label [PRO:DNx] synonym: "myeloid cell-specific leucine-rich glycoprotein (human)" EXACT [UniProtKB:P08571] xref: UniProtKB:P08571 is_a: PR:000001889 ! CD14 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001889 ! CD14 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P08920 name: T-cell surface antigen CD2 (mouse) namespace: protein def: "A CD2 molecule that is encoded in the genome of mouse." [OMA:P08920, PRO:DNx] comment: Category=organism-gene. synonym: "Cd2" RELATED Gene-based [UniProtKB:P08920] synonym: "CD2 (mouse)" EXACT [UniProtKB:P08920] synonym: "LFA-2 (mouse)" EXACT [UniProtKB:P08920] synonym: "LFA-3 receptor (mouse)" EXACT [UniProtKB:P08920] synonym: "Ly-37" RELATED Gene-based [UniProtKB:P08920] synonym: "lymphocyte antigen 37 (mouse)" EXACT [UniProtKB:P08920] synonym: "mCD2" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T11/Leu-5 (mouse)" EXACT [UniProtKB:P08920] xref: UniProtKB:P08920 is_a: PR:000001083 ! CD2 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001083 ! CD2 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P10810 name: monocyte differentiation antigen CD14 (mouse) namespace: protein def: "A CD14 molecule that is encoded in the genome of mouse." [OMA:P10810, PRO:WCB] comment: Category=organism-gene. synonym: "Cd14" RELATED Gene-based [UniProtKB:P10810] synonym: "CD14 (mouse)" EXACT [UniProtKB:P10810] synonym: "mCD14" EXACT PRO-short-label [PRO:DNx] synonym: "myeloid cell-specific leucine-rich glycoprotein (mouse)" EXACT [UniProtKB:P10810] xref: UniProtKB:P10810 is_a: PR:000001889 ! CD14 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001889 ! CD14 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P11215 name: integrin alpha-M (human) namespace: protein def: "An integrin alpha-M that is encoded in the genome of human." [PRO:DNx, UniProtKB:P11215] comment: Category=organism-gene. synonym: "CD11 antigen-like family member B (human)" EXACT [UniProtKB:P11215] synonym: "CD11B" RELATED Gene-based [UniProtKB:P11215] synonym: "cell surface glycoprotein MAC-1 subunit alpha (human)" EXACT [UniProtKB:P11215] synonym: "CR-3 alpha chain (human)" EXACT [UniProtKB:P11215] synonym: "CR3A" RELATED Gene-based [UniProtKB:P11215] synonym: "hITGAM" EXACT PRO-short-label [PRO:DNx] synonym: "ITGAM" RELATED Gene-based [UniProtKB:P11215] synonym: "leukocyte adhesion receptor MO1 (human)" EXACT [UniProtKB:P11215] synonym: "neutrophil adherence receptor (human)" EXACT [UniProtKB:P11215] xref: UniProtKB:P11215 is_a: PR:000001012 ! integrin alpha-M is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001012 ! integrin alpha-M intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P11836 name: B-lymphocyte antigen CD20 (human) namespace: protein def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P11836] comment: Category=organism-gene. synonym: "B-lymphocyte surface antigen B1 (human)" EXACT [UniProtKB:P11836] synonym: "Bp35 (human)" EXACT [UniProtKB:P11836] synonym: "CD20" RELATED Gene-based [UniProtKB:P11836] synonym: "hMS4A1" EXACT PRO-short-label [PRO:DNx] synonym: "leukocyte surface antigen Leu-16 (human)" EXACT [UniProtKB:P11836] synonym: "membrane-spanning 4-domains subfamily A member 1 (human)" EXACT [UniProtKB:P11836] synonym: "MS4A1" RELATED Gene-based [UniProtKB:P11836] xref: UniProtKB:P11836 is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P13379 name: T-cell surface glycoprotein CD5 (mouse) namespace: protein def: "A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse." [OMA:P13379, PRO:DNx] comment: Category=organism-gene. synonym: "Cd5" RELATED Gene-based [UniProtKB:P13379] synonym: "CD5 (mouse)" EXACT [UniProtKB:P13379] synonym: "Ly-1" RELATED Gene-based [UniProtKB:P13379] synonym: "lymphocyte antigen 1 (mouse)" EXACT [UniProtKB:P13379] synonym: "Lyt-1 (mouse)" EXACT [UniProtKB:P13379] synonym: "mCD5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P13379 is_a: PR:000001839 ! T-cell surface glycoprotein CD5 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001839 ! T-cell surface glycoprotein CD5 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P13591 name: neural cell adhesion molecule 1 (human) namespace: protein def: "A neural cell adhesion molecule 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P13591] comment: Category=organism-gene. synonym: "CD56 (human)" EXACT [UniProtKB:P13591] synonym: "hNCAM1" EXACT PRO-short-label [PRO:DNx] synonym: "N-CAM-1 (human)" EXACT [UniProtKB:P13591] synonym: "NCAM" RELATED Gene-based [UniProtKB:P13591] synonym: "NCAM-1 (human)" EXACT [UniProtKB:P13591] synonym: "NCAM1" RELATED Gene-based [UniProtKB:P13591] xref: UniProtKB:P13591 is_a: PR:000001024 ! neural cell adhesion molecule 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001024 ! neural cell adhesion molecule 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P13595 name: neural cell adhesion molecule 1 (mouse) namespace: protein def: "A neural cell adhesion molecule 1 that is encoded in the genome of mouse." [OMA:P13595, PRO:DNx] comment: Category=organism-gene. synonym: "CD56 (mouse)" EXACT [UniProtKB:P13595] synonym: "mNCAM1" EXACT PRO-short-label [PRO:DNx] synonym: "N-CAM-1 (mouse)" EXACT [UniProtKB:P13595] synonym: "Ncam" RELATED Gene-based [UniProtKB:P13595] synonym: "NCAM-1 (mouse)" EXACT [UniProtKB:P13595] synonym: "Ncam1" RELATED Gene-based [UniProtKB:P13595] xref: UniProtKB:P13595 is_a: PR:000001024 ! neural cell adhesion molecule 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001024 ! neural cell adhesion molecule 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P15391 name: B-lymphocyte antigen CD19 (human) namespace: protein def: "A CD19 molecule that is encoded in the genome of human." [] comment: Category=organism-gene. synonym: "B-lymphocyte surface antigen B4 (human)" EXACT [UniProtKB:P15391] synonym: "CD19" RELATED Gene-based [UniProtKB:P15391] synonym: "differentiation antigen CD19 (human)" EXACT [UniProtKB:P15391] synonym: "hCD19" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen Leu-12 (human)" EXACT [UniProtKB:P15391] xref: UniProtKB:P15391 is_a: PR:000001002 ! CD19 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001002 ! CD19 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16871 name: interleukin-7 receptor subunit alpha (human) namespace: protein def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of human." [PRO:WCB, UniProtKB:P16871] comment: Category=organism-gene. synonym: "CD127 (human)" EXACT [UniProtKB:P16871] synonym: "CDw127 (human)" EXACT [UniProtKB:P16871] synonym: "hIL7R" EXACT PRO-short-label [PRO:DNx] synonym: "IL-7 receptor subunit alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7R subunit alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7R-alpha (human)" EXACT [UniProtKB:P16871] synonym: "IL-7RA (human)" EXACT [UniProtKB:P16871] synonym: "IL7R" RELATED Gene-based [UniProtKB:P16871] xref: UniProtKB:P16871 is_a: PR:000001869 ! interleukin-7 receptor subunit alpha is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P16872 name: interleukin-7 receptor subunit alpha (mouse) namespace: protein def: "An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse." [OMA:P16872, PRO:DNx] comment: Category=organism-gene. synonym: "CD127 (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7 receptor subunit alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7R subunit alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7R-alpha (mouse)" EXACT [UniProtKB:P16872] synonym: "IL-7RA (mouse)" EXACT [UniProtKB:P16872] synonym: "Il7r" RELATED Gene-based [UniProtKB:P16872] synonym: "mIL7R" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P16872 is_a: PR:000001869 ! interleukin-7 receptor subunit alpha is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001869 ! interleukin-7 receptor subunit alpha intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P17542 name: T-cell acute lymphocytic leukemia protein 1 (human) namespace: protein def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17542] comment: Category=organism-gene. synonym: "BHLHA17" RELATED Gene-based [UniProtKB:P17542] synonym: "class A basic helix-loop-helix protein 17 (human)" EXACT [UniProtKB:P17542] synonym: "hTAL1" EXACT PRO-short-label [PRO:DNx] synonym: "SCL" RELATED Gene-based [UniProtKB:P17542] synonym: "Stem cell protein (human)" EXACT [UniProtKB:P17542] synonym: "T-cell leukemia/lymphoma protein 5 (human)" EXACT [UniProtKB:P17542] synonym: "TAL-1 (human)" EXACT [UniProtKB:P17542] synonym: "TAL1" RELATED Gene-based [UniProtKB:P17542] synonym: "TCL5" RELATED Gene-based [UniProtKB:P17542] xref: Reactome:R-HSA-8956511 "PR:P17542 located_in GO:0005654" xref: UniProtKB:P17542 is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P19437 name: B-lymphocyte antigen CD20 (mouse) namespace: protein def: "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse." [OMA:P19437, PRO:DNx] comment: Category=organism-gene. synonym: "B-cell differentiation antigen Ly-44 (mouse)" EXACT [UniProtKB:P19437] synonym: "Cd20" RELATED Gene-based [UniProtKB:P19437] synonym: "CD20 (mouse)" EXACT [UniProtKB:P19437] synonym: "Ly-44" RELATED Gene-based [UniProtKB:P19437] synonym: "lymphocyte antigen 44 (mouse)" EXACT [UniProtKB:P19437] synonym: "membrane-spanning 4-domains subfamily A member 1 (mouse)" EXACT [UniProtKB:P19437] synonym: "mMS4A1" EXACT PRO-short-label [PRO:DNx] synonym: "Ms4a1" RELATED Gene-based [UniProtKB:P19437] synonym: "Ms4a2" RELATED Gene-based [UniProtKB:P19437] xref: UniProtKB:P19437 is_a: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001289 ! membrane-spanning 4-domains subfamily A member 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P22091 name: T-cell acute lymphocytic leukemia protein 1 homolog (mouse) namespace: protein def: "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse." [OMA:P22091, PRO:DNx] comment: Category=organism-gene. synonym: "mTAL1" EXACT PRO-short-label [PRO:DNx] synonym: "Scl" RELATED Gene-based [UniProtKB:P22091] synonym: "Stem cell protein (mouse)" EXACT [UniProtKB:P22091] synonym: "Tal-1" RELATED Gene-based [UniProtKB:P22091] synonym: "TAL-1 (mouse)" EXACT [UniProtKB:P22091] synonym: "Tal1" RELATED Gene-based [UniProtKB:P22091] xref: UniProtKB:P22091 is_a: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000016043 ! T-cell acute lymphocytic leukemia protein 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P22646 name: T-cell surface glycoprotein CD3 epsilon chain (mouse) namespace: protein def: "A CD3 epsilon that is encoded in the genome of mouse." [OMA:P22646, PRO:DNx] comment: Category=organism-gene. synonym: "Cd3e" RELATED Gene-based [UniProtKB:P22646] synonym: "CD3e (mouse)" EXACT [UniProtKB:P22646] synonym: "mCD3E" EXACT PRO-short-label [PRO:DNx] synonym: "T-cell surface antigen T3/Leu-4 epsilon chain (mouse)" EXACT [UniProtKB:P22646] xref: UniProtKB:P22646 is_a: PR:000001020 ! CD3 epsilon is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001020 ! CD3 epsilon intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P25918 name: B-lymphocyte antigen CD19 (mouse) namespace: protein def: "A CD19 molecule that is encoded in the genome of mouse." [OMA:P25918, PRO:DNx] comment: Category=organism-gene. synonym: "Cd19" RELATED Gene-based [UniProtKB:P25918] synonym: "CD19 (mouse)" EXACT [UniProtKB:P25918] synonym: "differentiation antigen CD19 (mouse)" EXACT [UniProtKB:P25918] synonym: "mCD19" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P25918 is_a: PR:000001002 ! CD19 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001002 ! CD19 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P28906 name: hematopoietic progenitor cell antigen CD34 (human) namespace: protein def: "A CD34 molecule that is encoded in the genome of human." [] comment: Category=organism-gene. synonym: "CD34" RELATED Gene-based [UniProtKB:P28906] synonym: "hCD34" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P28906 is_a: PR:000001003 ! CD34 molecule is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001003 ! CD34 molecule intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P33151 name: cadherin-5 (human) namespace: protein def: "A cadherin-5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P33151] comment: Category=organism-gene. synonym: "7B4 antigen (human)" EXACT [UniProtKB:P33151] synonym: "CD144 (human)" EXACT [UniProtKB:P33151] synonym: "CDH5" RELATED Gene-based [UniProtKB:P33151] synonym: "hCDH5" EXACT PRO-short-label [PRO:DNx] synonym: "vascular endothelial cadherin (human)" EXACT [UniProtKB:P33151] synonym: "VE-cadherin (human)" EXACT [UniProtKB:P33151] xref: UniProtKB:P33151 is_a: PR:000001444 ! cadherin-5 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000001444 ! cadherin-5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P35461 name: lymphocyte antigen 6G (mouse) namespace: protein def: "A lymphocyte antigen 6G that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P35461] comment: Category=organism-gene. synonym: "Ly-6G (mouse)" EXACT [UniProtKB:P35461] synonym: "Ly-6G.1 (mouse)" EXACT [UniProtKB:P35461] synonym: "Ly6g" RELATED Gene-based [UniProtKB:P35461] synonym: "mLy6g" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35461 is_a: PR:000002978 ! lymphocyte antigen 6G is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000002978 ! lymphocyte antigen 6G intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P35918 name: vascular endothelial growth factor receptor 2 (mouse) namespace: protein def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse." [OMA:P35918, PRO:DNx] comment: Category=organism-gene. synonym: "CD309 (mouse)" EXACT [UniProtKB:P35918] synonym: "fetal liver kinase 1 (mouse)" EXACT [UniProtKB:P35918] synonym: "Flk-1" RELATED Gene-based [UniProtKB:P35918] synonym: "FLK-1 (mouse)" EXACT [UniProtKB:P35918] synonym: "Flk1" RELATED Gene-based [UniProtKB:P35918] synonym: "Kdr" RELATED Gene-based [UniProtKB:P35918] synonym: "kinase NYK (mouse)" EXACT [UniProtKB:P35918] synonym: "mKDR" EXACT PRO-short-label [PRO:DNx] synonym: "protein-tyrosine kinase receptor flk-1 (mouse)" EXACT [UniProtKB:P35918] synonym: "VEGFR-2 (mouse)" EXACT [UniProtKB:P35918] xref: UniProtKB:P35918 is_a: PR:000002112 ! vascular endothelial growth factor receptor 2 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P35968 name: vascular endothelial growth factor receptor 2 (human) namespace: protein def: "A vascular endothelial growth factor receptor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P35968] comment: Category=organism-gene. synonym: "CD309 (human)" EXACT [UniProtKB:P35968] synonym: "fetal liver kinase 1 (human)" EXACT [UniProtKB:P35968] synonym: "FLK-1 (human)" EXACT [UniProtKB:P35968] synonym: "FLK1" RELATED Gene-based [UniProtKB:P35968] synonym: "hKDR" EXACT PRO-short-label [PRO:DNx] synonym: "KDR" RELATED Gene-based [UniProtKB:P35968] synonym: "kinase insert domain receptor (human)" EXACT [UniProtKB:P35968] synonym: "protein-tyrosine kinase receptor flk-1 (human)" EXACT [UniProtKB:P35968] synonym: "VEGFR-2 (human)" EXACT [UniProtKB:P35968] synonym: "VEGFR2" RELATED Gene-based [UniProtKB:P35968] xref: DTO:03100560 xref: UniProtKB:P35968 is_a: PR:000002112 ! vascular endothelial growth factor receptor 2 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000002112 ! vascular endothelial growth factor receptor 2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P37237 name: fibroblast growth factor 8 (mouse) namespace: protein def: "A fibroblast growth factor 8 that is encoded in the genome of mouse." [OMA:P37237, PRO:DNx] comment: Category=organism-gene. synonym: "Aigf" RELATED Gene-based [UniProtKB:P37237] synonym: "AIGF (mouse)" EXACT [UniProtKB:P37237] synonym: "androgen-induced growth factor (mouse)" EXACT [UniProtKB:P37237] synonym: "FGF-8 (mouse)" EXACT [UniProtKB:P37237] synonym: "Fgf8" RELATED Gene-based [UniProtKB:P37237] synonym: "HBGF-8 (mouse)" RELATED [UniProtKB:P37237] synonym: "heparin-binding growth factor 8 (mouse)" RELATED [UniProtKB:P37237] synonym: "mFGF8" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P37237 is_a: PR:000007499 ! fibroblast growth factor 8 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000007499 ! fibroblast growth factor 8 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P55075 name: fibroblast growth factor 8 (human) namespace: protein def: "A fibroblast growth factor 8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P55075] comment: Category=organism-gene. synonym: "AIGF" RELATED Gene-based [UniProtKB:P55075] synonym: "androgen-induced growth factor (human)" EXACT [UniProtKB:P55075] synonym: "FGF-8 (human)" EXACT [UniProtKB:P55075] synonym: "FGF8" RELATED Gene-based [UniProtKB:P55075] synonym: "HBGF-8 (human)" BROAD [UniProtKB:P55075] synonym: "heparin-binding growth factor 8 (human)" BROAD [UniProtKB:P55075] synonym: "hFGF8" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P55075 is_a: PR:000007499 ! fibroblast growth factor 8 is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000007499 ! fibroblast growth factor 8 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P55284 name: cadherin-5 (mouse) namespace: protein def: "A cadherin-5 that is encoded in the genome of mouse." [OMA:P55284, PRO:DNx] comment: Category=organism-gene. synonym: "CD144 (mouse)" EXACT [UniProtKB:P55284] synonym: "Cdh5" RELATED Gene-based [UniProtKB:P55284] synonym: "mCDH5" EXACT PRO-short-label [PRO:DNx] synonym: "vascular endothelial cadherin (mouse)" EXACT [UniProtKB:P55284] synonym: "VE-cadherin (mouse)" EXACT [UniProtKB:P55284] xref: UniProtKB:P55284 is_a: PR:000001444 ! cadherin-5 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001444 ! cadherin-5 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q15465 name: sonic hedgehog protein (human) namespace: protein def: "A sonic hedgehog protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15465] comment: Category=organism-gene. synonym: "HHG-1 (human)" EXACT [UniProtKB:Q15465] synonym: "hSHH" EXACT PRO-short-label [PRO:DNx] synonym: "SHH" RELATED Gene-based [UniProtKB:Q15465] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human)" EXACT [UniProtKB:Q15465] synonym: "ShhNC (human)" EXACT [UniProtKB:Q15465] xref: UniProtKB:Q15465 is_a: PR:000014841 ! sonic hedgehog protein is_a: PR:000029067 ! Homo sapiens protein intersection_of: PR:000014841 ! sonic hedgehog protein intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q62226 name: sonic hedgehog protein (mouse) namespace: protein def: "A sonic hedgehog protein that is encoded in the genome of mouse." [OMA:Q62226, PRO:DNx] comment: Category=organism-gene. synonym: "HHG-1 (mouse)" EXACT [UniProtKB:Q62226] synonym: "Hhg1" RELATED Gene-based [UniProtKB:Q62226] synonym: "mSHH" EXACT PRO-short-label [PRO:DNx] synonym: "Shh" RELATED Gene-based [UniProtKB:Q62226] synonym: "SHH (mouse)" EXACT [UniProtKB:Q62226] synonym: "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (mouse)" EXACT [UniProtKB:Q62226] synonym: "ShhNC (mouse)" EXACT [UniProtKB:Q62226] xref: UniProtKB:Q62226 is_a: PR:000014841 ! sonic hedgehog protein is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000014841 ! sonic hedgehog protein intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q62351 name: transferrin receptor protein 1 (mouse) namespace: protein def: "A transferrin receptor protein 1 that is encoded in the genome of mouse." [OMA:Q62351, PRO:DNx] comment: Category=organism-gene. synonym: "CD71 (mouse)" EXACT [UniProtKB:Q62351] synonym: "mTFRC" EXACT PRO-short-label [PRO:DNx] synonym: "TfR (mouse)" EXACT [UniProtKB:Q62351] synonym: "TfR1 (mouse)" EXACT [UniProtKB:Q62351] synonym: "Tfrc" RELATED Gene-based [UniProtKB:Q62351] synonym: "TR (mouse)" RELATED [UniProtKB:Q62351] synonym: "Trfr" RELATED Gene-based [UniProtKB:Q62351] xref: UniProtKB:Q62351 is_a: PR:000001945 ! transferrin receptor protein 1 is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001945 ! transferrin receptor protein 1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q64314 name: hematopoietic progenitor cell antigen CD34 (mouse) namespace: protein def: "A CD34 molecule that is encoded in the genome of mouse." [OMA:Q64314, PRO:DNx] comment: Category=organism-gene. synonym: "Cd34" RELATED Gene-based [UniProtKB:Q64314] synonym: "CD34 (mouse)" EXACT [UniProtKB:Q64314] synonym: "mCD34" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q64314 is_a: PR:000001003 ! CD34 molecule is_a: PR:000029032 ! Mus musculus protein intersection_of: PR:000001003 ! CD34 molecule intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: RO:0002577 name: system def: "A material entity consisting of multiple components that are causally integrated." [] is_a: BFO:0000040 ! material entity property_value: editor_note "May be replaced by a BFO class, as discussed in http://www.jbiomedsem.com/content/4/1/43" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "http://www.jbiomedsem.com/content/4/1/43" xsd:string [Term] id: Subset is_a: IAO:0000102 ! data about an ontology part [Term] id: UBEORN:7500082 name: obsolete tibia diaphysis width comment: Term already exists. synonym: "IAO:0000423" EXACT [] relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: http://purl.org/dc/elements/1.1/date "2021-07-27T23:35:45Z" xsd:dateTime is_obsolete: true replaced_by: FOVT:0000026 [Term] id: UBERON:0000000 name: processual entity namespace: uberon def: "An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity." [span:ProcessualEntity] subset: common_anatomy subset: upper_level is_a: BFO:0000003 ! occurrent disjoint_from: UBERON:0001062 ! anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000003 name: naris namespace: uberon def: "Orifice of the olfactory system. The naris is the route by which odorants enter the olfactory system[MAH]." [http://orcid.org/0000-0001-9114-8737] subset: uberon_slim subset: vertebrate_core xref: AAO:0000311 xref: EHDAA2:0001225 xref: EHDAA:9083 xref: EMAPA:17847 xref: galen:Naris xref: MA:0000282 xref: SCTID:272650008 xref: VHOG:0000663 is_a: UBERON:0000161 ! orifice intersection_of: UBERON:0000161 ! orifice intersection_of: connects UBERON:0001707 ! nasal cavity intersection_of: part_of UBERON:0005725 ! olfactory system relationship: connects UBERON:0001707 ! nasal cavity relationship: in_lateral_side_of UBERON:0000033 {gci_relation="part_of", gci_filler="NCBITaxon:7776", notes="hagfish have median nostril"} ! head relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0000033 {source="ZFA"} ! head relationship: part_of UBERON:0005725 ! olfactory system property_value: UBPROP:0000001 "One of paired external openings of the nasal chamber.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000311", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "Naris refer to the external and interior naris (choana) of tetrapods, and to anterior and posterior naris of zebrafish. It seems now accepted that the structure is homologous: The choana, a unique 'internal nostril' opening from the nasal sac into the roof of the mouth, is a key part of the tetrapod (land vertebrate) respiratory system. It was the first component of the tetrapod body plan to evolve, well before the origin of limbs, and is therefore crucial to our understanding of the beginning of the fish-tetrapod transition. (...) Here we present new material of Kenichthys, a 395-million-year-old fossil fish from China, that provides direct evidence for the origin of the choana and establishes its homology: it is indeed a displaced posterior external nostril that, during a brief transitional stage illustrated by Kenichthys, separated the maxilla from the premaxilla.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000663", ontology="VHOG", source="DOI:10.1038/nature02843 Zhu M, Ahlberg PE, The origin of the internal nostril in tetrapodes. Nature (2004)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "in actinopterygians, both pairs of nares are external. In tetrapods, the exhalant empties into the buccal cavity" xsd:string property_value: UBPROP:0000012 "we have classified this as an orifice, according to FMA. Note that in FMA, orifices are immaterial entities, but in ZFA this is a surface structure" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000004 name: nose namespace: uberon def: "The olfactory organ of vertebrates, consisting of nares, olfactory epithelia and the structures and skeletal framework of the nasal cavity." [UBERON:cjm] subset: efo_slim subset: major_organ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nasal sac" EXACT SENSU [ZFA:0000047] synonym: "nasus" RELATED LATIN [Wikipedia:Nose] synonym: "nose" EXACT HUMAN_PREFERRED [MA:0000281] synonym: "olfactory apparatus" RELATED [UBERON:cjm] synonym: "peripheral olfactory organ" EXACT [ZFA:0000047] synonym: "proboscis" RELATED [] xref: BTO:0000840 xref: CALOHA:TS-2037 xref: EHDAA2:0001274 xref: EHDAA:1502 xref: EMAPA:16542 xref: EV:0100037 xref: EV:0100370 xref: FMA:46472 xref: GAID:77 xref: galen:Nose xref: MA:0000281 xref: MAT:0000139 xref: MESH:D009666 xref: MIAA:0000139 xref: NCIT:C12756 xref: SCTID:181195007 xref: TAO:0000047 xref: UMLS:C0028429 {source="ncithesaurus:Nose"} xref: Wikipedia:Nose xref: ZFA:0000047 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000475 ! organism subdivision is_a: UBERON:0002268 ! olfactory organ is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: capable_of_part_of GO:0007608 ! sensory perception of smell relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system relationship: contributes_to_morphology_of UBERON:0001456 ! face relationship: develops_from UBERON:0003050 {source="ZFA"} ! olfactory placode relationship: has_skeleton UBERON:0006813 ! nasal skeleton relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001004 {gci_relation="part_of", gci_filler="NCBITaxon:32523", source="PMID:25312359"} ! respiratory system relationship: part_of UBERON:0001456 {source="FMA", source="ZFA-def"} ! face relationship: part_of UBERON:0004089 {gci_relation="part_of", gci_filler="NCBITaxon:7776", notes="midface division only makes sense for gnathostomes"} ! midface property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d0/Canine-nose.jpg" xsd:anyURI property_value: UBPROP:0000001 "a protuberance in vertebrates that houses the nostrils, or nares, which admit and expel air for respiration in conjunction with the mouth. Behind the nose are the olfactory mucosa and the sinuses. Behind the nasal cavity, air next passes through the pharynx, shared with the digestive system, and then into the rest of the respiratory system. In humans, the nose is located centrally on the face; on most other mammals, it is on the upper tip of the snout[WP]. GO: The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity)[Wikipedia:Nose]." xsd:string {source="Wikipedia:Nose"} property_value: UBPROP:0000001 "Organ that is the specialized structure of the face that contains olfactory neurons. The peripheral olfactory organ is paired[ZFA:0000047]." xsd:string {source="ZFA:0000047"} property_value: UBPROP:0000001 "the organ that is specialized for smell and is part of the respiratory system" xsd:string {source="MP:0002233"} property_value: UBPROP:0000008 "the structure of the nose varies across vertebrates. In tetrapods the nose is part of the respiratory system.[PMID:25312359]" xsd:string [Term] id: UBERON:0000005 name: chemosensory organ namespace: uberon subset: functional_classification subset: uberon_slim synonym: "chemosensory sensory organ" EXACT [FBbt:00005157] xref: FBbt:00005157 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus relationship: capable_of GO:0007606 ! sensory perception of chemical stimulus relationship: part_of UBERON:0001016 ! nervous system relationship: part_of UBERON:0005726 ! chemosensory system [Term] id: UBERON:0000006 name: islet of Langerhans namespace: uberon def: "The clusters of hormone-producing cells that are scattered throughout the pancreas." [MA:0000127, MESH:A03.734.414, MP:0005215] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "island of Langerhans" RELATED [BTO:0000991] synonym: "island of pancreas" RELATED [BTO:0000991] synonym: "islets of Langerhans" RELATED [] synonym: "pancreatic insula" EXACT [] synonym: "pancreatic islet" EXACT [] xref: AAO:0010406 xref: BTO:0000991 xref: CALOHA:TS-0741 xref: EFO:0000856 xref: EMAPA:32927 xref: EV:0100130 xref: FMA:16016 xref: GAID:324 xref: MA:0000127 xref: MAT:0000076 xref: MESH:D007515 xref: MIAA:0000076 xref: NCIT:C12608 xref: UMLS:C0022131 {source="ncithesaurus:Islet_of_Langerhans"} xref: VHOG:0000646 xref: Wikipedia:Islets_of_Langerhans xref: XAO:0000159 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0034922 ! cell cluster relationship: contributes_to_morphology_of UBERON:0000016 ! endocrine pancreas relationship: has_part CL:0000168 {source="PMID:16417468"} ! insulin secreting cell relationship: has_part CL:0000172 {source="PMID:16417468"} ! somatostatin secreting cell relationship: has_part CL:0000696 {gci_relation="part_of", gci_filler="NCBITaxon:7778", source="PMID:16417468"} ! PP cell relationship: has_part CL:0000696 {gci_filler="NCBITaxon:117570", gci_relation="part_of", source="PMID:16417468"} ! PP cell relationship: has_part CL:0002067 {source="PMID:16417468"} ! type A enteroendocrine cell relationship: part_of UBERON:0000016 ! endocrine pancreas property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical structure which consists of glands developed from pancreatic ducts in the larvae and secrete insulin.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010406", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Mammals, birds, reptiles and amphibians have a pancreas with similar histology and mode of development, while in some fish, the islet cells are segregated as Brockmann bodies.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000646", ontology="VHOG", source="PMID:7600975 Slack JMW, Developmental biology of the pancreas. Development (1995)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "A primitive exocrine pancreas can be found in holocephalan cartilaginous fish; a pancreatic duct directly ending in the gut lumen is connected to a glandular structure made of exocrine cells and associated with cell islets, which comprises three different hormone-producing cell types: insulin, somatostatin and glucagon (Yui and Fujita, 1986)" xsd:string {source="PMID:16417468"} property_value: UBPROP:0000202 FMA:76489 [Term] id: UBERON:0000009 name: submucosa namespace: uberon def: "A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]." [Wikipedia:Submucosa] subset: pheno_slim subset: uberon_slim synonym: "organ submucosa" EXACT [FMA:85391] synonym: "region of submucosa" EXACT [FMA:85392] synonym: "submucosa of organ" EXACT [FMA:85391] synonym: "submucosa of region of organ" EXACT [FMA:85392] synonym: "submucous layer" RELATED [BTO:0002107] synonym: "tela submucosa" RELATED [BTO:0002107] synonym: "tunica submucosa" RELATED [] xref: BTO:0002107 xref: FMA:85391 xref: FMA:85392 xref: NCIT:C13167 xref: SCTID:68439008 xref: UMLS:C0225344 {source="ncithesaurus:Submucosa"} xref: Wikipedia:Submucosa is_a: UBERON:0004923 ! organ component layer relationship: composed_primarily_of UBERON:0002384 ! connective tissue relationship: immediately_deep_to UBERON:0000344 ! mucosa relationship: only_in_taxon NCBITaxon:7711 ! Chordata property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI property_value: UBPROP:0000007 "submucosal" xsd:string [Term] id: UBERON:0000010 name: peripheral nervous system namespace: uberon def: "A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." [GO:0007422] subset: cumbo subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "pars peripherica" EXACT LATIN [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] synonym: "PNS" BROAD ABBREVIATION [] synonym: "systema nervosum periphericum" EXACT LATIN [FMA:9903, FMA:TA, Wikipedia:Peripheral_nervous_system] xref: AAO:0000429 xref: BAMS:PNS xref: BILA:0000081 xref: BIRNLEX:1111 xref: BTO:0001028 xref: CALOHA:TS-0808 xref: EFO:0000891 xref: EHDAA2:0001445 xref: EHDAA:2893 xref: EMAPA:16665 xref: EV:0100335 xref: FBbt:00005098 xref: FMA:9903 xref: GAID:715 xref: MA:0000218 xref: MAT:0000338 xref: MESH:D017933 xref: MIAA:0000338 xref: NCIT:C12465 xref: neuronames:3232 xref: SCTID:362292005 xref: TAO:0000142 xref: UMLS:C0206417 {source="ncithesaurus:Peripheral_Nervous_System", source="BIRNLEX:1111"} xref: UMLS:C1305921 {source="BIRNLEX:1111"} xref: VHOG:0000399 xref: Wikipedia:Peripheral_nervous_system xref: XAO:0000178 xref: ZFA:0000142 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0001016 ! nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Nervous structures including ganglia outside of the central nervous system. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000142", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of nervous system in which nerves extend throughout the body outside of the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000429", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The peripheral nervous system (PNS) is the part of the nervous system connected to the CNS which contains cranial nerves III - XII, spinal, peripheral and autonomic nerves. (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"} property_value: UBPROP:0000003 "(...) specific vertebrate traits within the chordate phylum such as skeletal tissues, PNS, and spectacular head and brain development, are linked to the NC (neural crest) and its derivatives.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000399", ontology="VHOG", source="DOI:10.1007/978-0-387-46954-6_6 Dupin E, Creuzet S, Le Douarin NM, The contribution of the neural crest to the vertebrate body. Advances in experimental medicine and biology (2006)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000011 name: parasympathetic nervous system namespace: uberon def: "The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia[GO]." [GO:0048486] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "parasympathetic part of autonomic division of nervous system" EXACT [] synonym: "pars parasympathica divisionis autonomici systematis nervosi" EXACT LATIN [FMA:9907, FMA:TA] synonym: "pars parasympathica divisionis autonomici systematis nervosi" RELATED LATIN [Wikipedia:Parasympathetic_nervous_system] synonym: "PNS - parasympathetic" EXACT [] xref: AAO:0010488 xref: BIRNLEX:2517 xref: BTO:0001833 xref: CALOHA:TS-2094 xref: EFO:0000894 xref: EHDA:10096 xref: EHDAA2:0001402 xref: EHDAA:4655 xref: EMAPA:17270 xref: FMA:9907 xref: GAID:708 xref: MA:0000223 xref: MAT:0000101 xref: MESH:D010275 xref: MIAA:0000101 xref: NCIT:C12764 xref: SCTID:362496006 xref: TAO:0001575 xref: UMLS:C0030510 {source="BIRNLEX:2517", source="ncithesaurus:Parasympathetic_Nervous_System"} xref: UMLS:C1305770 {source="BIRNLEX:2517"} xref: VHOG:0000755 xref: Wikipedia:Parasympathetic_nervous_system xref: ZFA:0001575 is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: contributes_to_morphology_of UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0002410 {source="FMA", source="MA", source="WP", source="ZFA-modified-from-isa"} ! autonomic nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI property_value: UBPROP:0000001 "Part of the autonomic nervous system which has opposing physiological effects of the sympathetic nervous system. Examples include decreasing the heart rate or dilating the blood vessels.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010488", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "In mammals, the autonomic nervous system is divided into two contrasting, antagonistic systems of control over visceral activity: the sympathetic system and the parasympathetic system (reference 1); In general, the teleosts may be considered phylogenetically the first class of vertebrates in which the heart is regulated by both sympathetic and parasympathetic neural pathways (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000755", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.634, DOI:10.1016/S0306-4530(98)00057-2 Porges SW, Love: an emergent property of the mammalian autonomic nervous system. Psychoneuroendocrinology (1998)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000012 name: somatic nervous system namespace: uberon def: "Part of peripheral nervous system that includes the somatic parts of the cranial and spinal nerves and their ganglia and the peripheral sensory receptors." [NLXANAT:100301] subset: pheno_slim subset: uberon_slim synonym: "PNS - somatic" EXACT [] synonym: "somatic nervous system, somatic division" EXACT [NLXANAT:100301] synonym: "somatic part of peripheral nervous system" EXACT [UBERON:cjm] synonym: "somatic peripheral nervous system" EXACT [NLXANAT:100301] xref: EFO:0000892 xref: FMA:9904 xref: MA:0002850 xref: MAT:0000099 xref: MIAA:0000099 xref: NLXANAT:100301 xref: Wikipedia:Somatic_nervous_system is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: contributes_to_morphology_of UBERON:0001016 ! nervous system relationship: part_of UBERON:0000010 ! peripheral nervous system [Term] id: UBERON:0000013 name: sympathetic nervous system namespace: uberon def: "The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]." [GO:0048485] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "pars sympathica divisionis autonomici systematis nervosi" EXACT LATIN [FMA:9906, FMA:TA] synonym: "pars sympathica divisionis autonomici systematis nervosi" RELATED LATIN [Wikipedia:Sympathetic_nervous_system] synonym: "sympathetic nervous system" EXACT [] synonym: "sympathetic part of autonomic division of nervous system" EXACT [] xref: AAO:0010487 xref: BIRNLEX:2516 xref: BTO:0001832 xref: CALOHA:TS-2050 xref: EFO:0000893 xref: EHDAA2:0001971 xref: EHDAA:3769 xref: EMAPA:16985 xref: FMA:9906 xref: GAID:710 xref: MA:0000225 xref: MESH:D013564 xref: MIAA:0000100 xref: NCIT:C12795 xref: SCTID:362484004 xref: TAO:0001576 xref: UMLS:C0039044 {source="BIRNLEX:2516", source="ncithesaurus:Sympathetic_Nervous_System"} xref: UMLS:C1269646 {source="BIRNLEX:2516"} xref: VHOG:0000384 xref: Wikipedia:Sympathetic_nervous_system xref: ZFA:0001576 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: contributes_to_morphology_of UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0002410 {source="FMA", source="MA", source="ZFA-modified-from-isa"} ! autonomic nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png" xsd:anyURI property_value: UBPROP:0000001 "Part of the autonomic nervous system which has opposing physiological effects of the parasympathetic nervous system. Examples include increasing the heart rate or constricting the blood vessels.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010487", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The part of the autonomic nervous system which chiefly contains adrenergic fibres and tends to control and reduce secretions, decrease the contractility and hence the tone of smooth muscles and provoke the contraction of blood vessels. Essentially, it consists of preganglionic fibres from the thoracic and upper lumbar parts of the spinal cord. These fibres, by means of delicate rami communicantes, cross over to ganglia sited in a pair of ganglionated cords on each side of the vertebral column or to more peripheral ganglia. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000384", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The autonomic nervous system is composed of three divisions: the sympathetic division, the parasympathetic division, and the enteric division. (...) In ray-finned teleost fishes, a sympathetic chain is present, and dual innervation of additional organs can be observed. A similar pattern can be found in amphibians (...). The evolution of the autonomic nervous system has been quite conservative, especially in the tetrapod lineage.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000384", ontology="VHOG", source="ISBN:978-0471210054 Butler AB and Hodos W, Comparative vertebrate neuroanatomy: Evolution and Adaptation (2005) p.461-463", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "has developmental contribution from NC in verteberates (https://github.com/obophenotype/uberon/wiki/The-neural-crest)" xsd:string [Term] id: UBERON:0000014 name: zone of skin namespace: uberon def: "Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Skin] subset: pheno_slim synonym: "portion of skin" EXACT [] synonym: "region of skin" EXACT [] synonym: "skin" EXACT [MA:0000151] synonym: "skin region" EXACT [] synonym: "skin zone" EXACT [] xref: EHDAA2:0001844 xref: EHDAA:6530 xref: EMAPA:17525 xref: EV:0100152 xref: FMA:86166 xref: GAID:933 xref: MA:0000151 xref: MAT:0000284 xref: MESH:D012867 xref: MIAA:0000284 xref: SCTID:20795001 xref: VHOG:0000860 xref: Wikipedia:Skin is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034944 {source="FMA"} ! zone of organ relationship: has_part UBERON:0001003 ! skin epidermis relationship: has_part UBERON:0002067 ! dermis relationship: part_of UBERON:0002097 ! skin of body property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e8/HumanSkinDiagram.jpg" xsd:anyURI property_value: IAO:0000232 "Note the distinction between the entire skin of the body, of which there is only 1 in an organism, and zones of skin, of which there can be many. Examples: skin of knee" xsd:string property_value: UBPROP:0000003 "(...) it is well-established that neural crest cells contribute to both the dermal skeleton (craniofacial bone, teeth, and the caudal fin rays of teleosts) and the integument, including craniofacial dermis and all pigment cells outside the retina (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000860", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2008.01043.x Vickaryous MK, Sire JY, The integumentary skeleton of tetrapods: origin, evolution, and development. J Anat (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "we assume that mouse, HOG and GAID all mean zone of skin when they say skin. We also choose skin as an exact synonym, as it is more intuitive" xsd:string [Term] id: UBERON:0000015 name: non-material anatomical boundary namespace: uberon def: "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." [CARO:0000010] comment: Except in the case of abstracted fiat boundaries such as the midline plane of an organism, all 2D anatomical entities have a 3 dimensional projection. For example, the surface of the shell of a muscle has a distinct shape that projects into the third dimension. Note that boundaries are 2D structures. They have no thickness - and so can not be sites of gene expression or gene product localisation. For this, use boundary region terms. subset: common_anatomy subset: upper_level synonym: "anatomical boundary" EXACT [CARO:0000010] xref: AEO:0000192 xref: CARO:0000010 xref: FMA:50705 is_a: UBERON:0000466 {source="CARO"} ! immaterial anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000016 name: endocrine pancreas namespace: uberon def: "The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin." [GO:GO, http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "endocrine pancreas" EXACT [] synonym: "endocrine part of pancreas" RELATED [BTO:0000650] synonym: "islets of Langerhans part of pancreas" RELATED [] synonym: "pars endocrina pancreatis" EXACT [] xref: BTO:0000650 xref: CALOHA:TS-1302 xref: EFO:0002542 xref: EMAPA:35305 xref: EV:0100129 xref: FMA:16018 xref: MA:0001582 xref: NCIT:C32509 xref: SCTID:361339003 xref: TAO:0001260 xref: VHOG:0000049 xref: Wikipedia:Islets_of_Langerhans xref: ZFA:0001260 is_a: UBERON:0000471 {source="ZFA"} ! compound organ component is_a: UBERON:0004119 ! endoderm-derived structure relationship: capable_of GO:0030073 {source="GO"} ! insulin secretion relationship: capable_of GO:0070091 {source="GO"} ! glucagon secretion relationship: capable_of GO:0070253 {source="GO"} ! somatostatin secretion relationship: composed_primarily_of UBERON:0000006 ! islet of Langerhans relationship: contributes_to_morphology_of UBERON:0001264 ! pancreas relationship: develops_from UBERON:0003923 ! dorsal pancreatic bud relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000949 {source="AAO", source="FMA", source="XAO"} ! endocrine system relationship: part_of UBERON:0001264 ! pancreas property_value: editor_note "create a separate class for distributed pancreas, eg cyclostomes?" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The part of the pancreas that acts as an endocrine gland, consisting of the islets of Langerhans, which secrete insulin and other hormones. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000049", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Pancreas"} property_value: UBPROP:0000001 "The zebrafish endocrine pancreas is composed of small groups of islet cells that are distributed throughout the exocrine pancreas. The islet cells produce insulin, glucagon and somatostatin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001260", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000049", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "endocrine and exocrine pancreas are not co-associated in hagfishes or lampreys" xsd:string {source="PMID:20959416"} [Term] id: UBERON:0000017 name: exocrine pancreas namespace: uberon def: "The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]." [GOC:GO, http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "exocrine component of pancreas" RELATED [] synonym: "exocrine pancreas" EXACT [] synonym: "exocrine part of pancreas" RELATED [BTO:0000434] synonym: "pars exocrina pancreatis" EXACT [] xref: AAO:0010407 xref: BTO:0000434 xref: CALOHA:TS-1241 xref: EMAPA:35328 xref: EV:0100093 xref: FMA:16017 xref: MA:0002415 xref: MESH:D046790 xref: NCIT:C32546 xref: SCTID:248202004 xref: TAO:0001249 xref: UMLS:C0553695 {source="ncithesaurus:Exocrine_Pancreas"} xref: VHOG:0000048 xref: Wikipedia:Exocrine_component_of_pancreas xref: XAO:0000137 xref: ZFA:0001249 is_a: UBERON:0000409 ! serous gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005177 ! trunk region element relationship: capable_of_part_of GO:0007586 ! digestion relationship: contributes_to_morphology_of UBERON:0001264 ! pancreas relationship: develops_from UBERON:0003924 ! ventral pancreatic bud relationship: has_part UBERON:0001263 ! pancreatic acinus relationship: has_part UBERON:0007329 ! pancreatic duct relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The exocrine pancreas is composed of acinar epithelial cells and ductal epithelium that manufacture the proteolytic enzymes and bicarbonate required for digestion.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001249", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The part of the pancreas that acts as an exocrine gland, consisting of the pancreatic acini, which produce pancreatic juice and secrete it into the intestine to aid in protein digestion. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000048", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Pancreas"} property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000048", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000018 name: compound eye namespace: uberon def: "A light sensing organ composed of ommatidia." [FB:gg, Wikipedia:Compound_eye] subset: organ_slim subset: uberon_slim synonym: "adult compound eye" RELATED [] synonym: "faceted eye" RELATED [] synonym: "Facettenauge" RELATED [BTO:0001921] synonym: "insect eye" RELATED [] synonym: "Komplexauge" RELATED [BTO:0001921] synonym: "zusammengesetztes Auge" RELATED [BTO:0001921] xref: BTO:0001921 xref: FBbt:00004508 xref: HAO:0000217 xref: TGMA:0000024 xref: Wikipedia:Compound_eye is_a: UBERON:0015165 ! multi-unit eye intersection_of: UBERON:0000970 ! eye intersection_of: composed_primarily_of UBERON:0000971 ! ommatidium relationship: composed_primarily_of UBERON:0000971 ! ommatidium relationship: only_in_taxon NCBITaxon:6656 {source="PMID:21062451"} ! Arthropoda property_value: seeAlso "https://github.com/obophenotype/uberon/issues/457" xsd:anyURI property_value: UBPROP:0000008 "The term compound eye is sometimes used for the multi-unit eyes of annelids, bivalves, echinoderms. We follow Richter et al and restrict this class to the arthropod structure for these structures" xsd:string {source="PMID:21062451"} [Term] id: UBERON:0000019 name: camera-type eye namespace: uberon def: "An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid." [GO:0043010, https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "camera-type eye plus associated structures" RELATED [] synonym: "eye" BROAD [FMA:54448] synonym: "eyes" RELATED PLURAL [TAO:0000107] synonym: "orbital part of face" RELATED [FMA:54448] synonym: "orbital region" RELATED [FMA:54448] synonym: "regio orbitalis" EXACT LATIN [FMA:54448, FMA:TA] synonym: "vertebrate eye" NARROW [] xref: AAO:0010340 xref: BIRNLEX:1169 xref: BTO:0004688 xref: EHDAA2:0000484 xref: EHDAA:936 xref: EMAPA:16198 xref: FMA:54448 xref: MA:0000261 xref: NCIT:C12401 xref: SCTID:181143004 xref: TAO:0000107 xref: UMLS:C0015392 {source="BIRNLEX:1169", source="ncithesaurus:Eye"} xref: UMLS:C1280202 {source="BIRNLEX:1169"} xref: VHOG:0000275 xref: XAO:0000179 xref: ZFA:0000107 is_a: UBERON:0000047 ! simple eye is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0015212 ! lateral structure relationship: develops_from UBERON:0003072 {evidence="definitional"} ! optic cup relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000965 ! lens of camera-type eye relationship: has_part UBERON:0000966 ! retina relationship: in_lateral_side_of UBERON:0000033 ! head relationship: part_of UBERON:0004088 ! orbital region property_value: UBPROP:0000001 "A cavitated compound organ that transduces light waves into neural signals.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000107", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000275", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "FMA distinguishes Eye (subdivision of face) which has its parts an Eyeball (organ), as well as other structures, and the orbit of skull. MA includes eyelid, conjunctiva and lacrimal apparatus as part of MA:eye - consistent with FMA - so we can infer that MA:eye is more like FMA:eye than FMA:eyeball. For other AOs this distinction is less meaningful - e.g. ZFA has no eyelid; XAO has no eyelid, but it has conjuctiva, which is considered part of the xao:eye. GO considers eyelid development part of eye development. See also notes on optic nerve - XAO, AAO and BTO consider this part of the eye. MA considers the eye muscles part of the eye, whereas FMA has a class 'orbital content' for this" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000020 name: sense organ namespace: uberon def: "An organ that is capable of transducing sensory stimulus to the nervous system." [https://github.com/obophenotype/uberon/issues/549, https://orcid.org/0000-0002-6601-2165] subset: uberon_slim synonym: "organ of sense organ system" EXACT [OBOL:accepted] synonym: "organ of sensory organ system" EXACT [OBOL:accepted] synonym: "organ of sensory system" EXACT [OBOL:accepted] synonym: "sense organ system organ" EXACT [OBOL:automatic] synonym: "sensillum" NARROW [WBbt:0006929] synonym: "sensor" RELATED [] synonym: "sensory organ" EXACT [] synonym: "sensory organ system organ" EXACT [OBOL:automatic] synonym: "sensory system organ" EXACT [OBOL:accepted] synonym: "Sinnesorgan" RELATED [BTO:0000202] xref: AEO:0000094 xref: BSA:0000121 xref: BTO:0000202 xref: CALOHA:TS-2043 xref: EHDAA2:0001824 xref: EHDAA:500 xref: EMAPA:35955 xref: FBbt:00005155 xref: GAID:63 xref: HAO:0000930 xref: MA:0000017 xref: MESH:D012679 xref: NCIT:C33224 xref: SCTID:244485009 xref: UMLS:C0935626 {source="ncithesaurus:Organ_of_the_Special_Sense"} xref: VHOG:0001407 xref: WBbt:0006929 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: capable_of GO:0050906 ! detection of stimulus involved in sensory perception relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: part_of UBERON:0001032 ! sensory system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI [Term] id: UBERON:0000025 name: tube namespace: uberon def: "Any hollow cylindrical anatomical structure containing a lumen through which substances are transported." [http://orcid.org/0000-0002-6601-2165] synonym: "anatomical tube" EXACT [] synonym: "duct" NARROW [] xref: galen:Tube is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: has_quality PATO:0002299 ! tubular relationship: has_part UBERON:0013522 ! subdivision of tube relationship: has_quality PATO:0002299 ! tubular property_value: IAO:0000232 "not every anatomical conduit is a tube - for example, a bone foramen is an opening in the bone, and there is no distinct separate tube structure. Tubes may transport large mixed objects (for example, a bolus of food in the digestive tube) or they may transport the secretions of a single gland (for example, gland ducts)" xsd:string property_value: UBPROP:0000007 "tubular" xsd:string [Term] id: UBERON:0000026 name: appendage namespace: uberon def: "Major subdivision of an organism that protrudes from the body[DOS, CARO]." [CARO:DOS] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "appendages" RELATED PLURAL [XAO:0000218] synonym: "extremitaet" RELATED [BTO:0001492] synonym: "extremity" RELATED [] synonym: "limbs/digits/tail" RELATED [MP:0000001] xref: AEO:0000193 xref: BILA:0000018 xref: BTO:0001492 xref: CARO:0010003 xref: EFO:0000799 xref: EHDAA2:0003193 xref: EMAPA:37283 {source="MA:th"} xref: EV:0100155 xref: FBbt:00007000 xref: HAO:0000144 xref: MAT:0000023 xref: MESH:D005121 xref: MIAA:0000023 xref: NCIT:C61460 xref: UMLS:C0598782 {source="ncithesaurus:Appendage"} xref: VSAO:0000075 xref: Wikipedia:Appendage xref: XAO:0000218 is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000001 "An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs[BILA][BILA:0000018]." xsd:string {source="BILA:0000018"} property_value: UBPROP:0000001 "Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified][GO:0048736]." xsd:string {source="GO:0048736"} property_value: UBPROP:0000007 "appendicular" xsd:string property_value: UBPROP:0000008 "this is currently a subtype of organism subdivision - which would exclude feathers" xsd:string [Term] id: UBERON:0000030 name: lamina propria namespace: uberon def: "A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions." [Wikipedia:Lamina_propria] subset: uberon_slim synonym: "lamina propria mucosa" EXACT [] synonym: "lamina propria mucosae" EXACT [] synonym: "tunica propria" RELATED [BTO:0002330] xref: BTO:0002330 xref: FMA:62517 xref: NCIT:C32918 xref: SCTID:298225002 xref: UMLS:C1179187 {source="ncithesaurus:Lamina_Propria"} xref: Wikipedia:Lamina_propria is_a: UBERON:0004923 ! organ component layer relationship: composed_primarily_of UBERON:0011825 ! loose connective tissue relationship: immediately_deep_to UBERON:0000483 ! epithelium relationship: part_of UBERON:0000344 ! mucosa property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/f/fb/GI_Organization.svg" xsd:anyURI [Term] id: UBERON:0000031 name: lamina propria of trachea namespace: uberon def: "A lamina propria that is part of a respiratory airway." [OBOL:automatic] synonym: "lamina propria mucosa of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of trachea" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of windpipe" EXACT [OBOL:automatic] synonym: "lamina propria of windpipe" EXACT [OBOL:automatic] synonym: "trachea lamina propria" EXACT [] synonym: "trachea lamina propria mucosa" EXACT [OBOL:automatic] synonym: "trachea lamina propria mucosae" EXACT [OBOL:automatic] synonym: "tracheal lamina propria" EXACT [] synonym: "windpipe lamina propria" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosa" EXACT [OBOL:automatic] synonym: "windpipe lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:35877 xref: FMA:265157 xref: MA:0001858 xref: NCIT:C49305 xref: UMLS:C1710457 {source="ncithesaurus:Trachea_Lamina_Propria"} is_a: UBERON:0004779 ! respiratory system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001005 ! respiratory airway relationship: part_of UBERON:0000379 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! tracheal mucosa [Term] id: UBERON:0000033 name: head namespace: uberon def: "The head is the anterior-most division of the body [GO]." [GO:0060322, Wikipedia:Head] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult head" NARROW [] synonym: "cephalic area" RELATED [SPD:0000016] synonym: "head (volume)" EXACT [FMA:7154] xref: AAO:0010335 xref: AEO:0000106 xref: BILA:0000115 xref: BIRNLEX:1230 xref: BTO:0000282 xref: CALOHA:TS-0436 xref: EFO:0000964 xref: EHDAA2:0003106 xref: EMAPA:31858 xref: FBbt:00000004 xref: FMA:7154 xref: GAID:61 xref: galen:Head xref: HAO:0000397 xref: MA:0000023 xref: MAT:0000294 xref: MESH:D006257 xref: MIAA:0000294 xref: NCIT:C12419 xref: SCTID:302548004 xref: SPD:0000016 xref: TAO:0001114 xref: TGMA:0000002 xref: UMLS:C0018670 {source="ncithesaurus:Head", source="BIRNLEX:1230"} xref: VHOG:0001644 xref: WBbt:0005739 xref: Wikipedia:Head xref: XAO:0003024 xref: ZFA:0001114 is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: has_skeleton UBERON:0003129 {gci_relation="part_of", gci_filler="NCBITaxon:7776"} ! skull relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0007811 ! craniocervical region property_value: RO:0002171 UBERON:0000948 property_value: UBPROP:0000001 "Organism subdivision that is the part of the body consisting of the cranial and pharyngeal regions.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010335", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Organism subdivision which is the part of the body which consists of the cranial and pharygeal regions.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001114", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Vertebrate evolution has been characterized by a fresh and vast array of cranial structures that collectively form the head.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001644", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.82", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000042 name: serous membrane namespace: uberon def: "Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Serous_membrane] subset: uberon_slim subset: vertebrate_core synonym: "serosa" RELATED [Wikipedia:Serous_membrane] synonym: "tunica serosa" EXACT LATIN [FMA:9581] synonym: "wall of serous sac" EXACT [FMA:9581] xref: FMA:9581 xref: GAID:19 xref: MESH:D012704 xref: NCIT:C13169 xref: SCTID:362878009 xref: TAO:0005425 xref: UMLS:C0036760 {source="ncithesaurus:Serosa"} xref: Wikipedia:Serous_membrane xref: ZFA:0005425 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure relationship: has_part UBERON:0001136 ! mesothelium relationship: has_part UBERON:0002384 ! connective tissue relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000060 ! anatomical wall property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI property_value: UBPROP:0000001 "A multi-tissue structure that is comprised of a secretory epithelial layer and a connective tissue layer.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005425", ontology="TAO", source="Wikipedia:Serous_membrane"} property_value: UBPROP:0000001 "a smooth membrane consisting of a thin layer of cells which excrete serous fluid. Serous membranes line and enclose several body cavities, known as serous cavities, where they secrete a lubricating fluid which reduces friction from muscle movement. Serosa is not to be confused with adventitia, a connective tissue layer which binds together structures rather than reducing friction between them. Each serous membrane is composed of a secretory epithelial layer and a connective tissue layer underneath. The epithelial layer, known as mesothelium, consists of a single layer of avascular flat nucleated cells (cuboidal epithelium) which produce the lubricating serous fluid. This fluid has a consistency similar to thin mucus. These cells are bound tightly to the underlying connective tissue. The connective tissue layer provides the blood vessels and nerves for the overlying secretory cells, and also serves as the binding layer which allows the whole serous membrane to adhere to organs and other structures.[WP]" xsd:string {source="Wikipedia:Serous_membrane"} property_value: UBPROP:0000012 "in FMA, SM = mesothelium + connective tissue. It excludes the cavity. Serous sac = SM + cavity. Note that the SM is a subtype of wall in FMA." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000043 name: tendon namespace: uberon def: "Dense regular connective tissue that connects muscle to bone[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073, Wikipedia:Tendon] subset: pheno_slim subset: uberon_slim synonym: "sinew" RELATED [Wikipedia:Tendon] synonym: "tendo" RELATED LATIN [Wikipedia:Tendon] xref: AEO:0000091 xref: BTO:0001356 xref: CALOHA:TS-1021 xref: EHDAA2:0003091 xref: EMAPA:35854 xref: EV:0100149 xref: FMA:9721 xref: GAID:276 xref: galen:Tendon xref: MA:0000115 xref: MESH:D013710 xref: NCIT:C13045 xref: SCTID:256667004 xref: UMLS:C0039508 {source="ncithesaurus:Tendon"} xref: VHOG:0001286 xref: VSAO:0000073 xref: Wikipedia:Tendon xref: XAO:0000173 xref: ZFA:0005647 is_a: UBERON:0007846 {source="VSAO"} ! dense regular connective tissue relationship: connects UBERON:0001474 ! bone element relationship: connects UBERON:0001630 ! muscle organ relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002204 {source="OG"} ! musculoskeletal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg" xsd:anyURI property_value: UBPROP:0000001 "Dense regular connective tissue that connects muscle to bone.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000073", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000003 "Phylogenetically, tendinous tissue first appears in the invertebrate chordate Branchiostoma as myosepta. This two-dimensional array of collagen fibers is highly organized, with fibers running along two primary axes. In hagfish the first linear tendons appear and the myosepta have developed specialized regions with unidirectional fiber orientation - a linear tendon within the flat sheet of myoseptum.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001286", ontology="VHOG", source="DOI:10.1016/S1095-6433(02)00241-6 Summers AP, Koob TJ, The evolution of tendon - morphology and material properties. Comparative Biochemistry and Physiology-Part A: Molecular and Integrative Physiology (2002)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in FMA, tendon is an organ component that with parts dense-irregular-connective-tissue of tendon and dense-irregular-connective-tissue of tendon sheath; we follow VSAO in making it a subtype of the former. In VSAO tendons connect muscle to bone; in WP the def states integument (e.g. auricular muscles) - but JB confirms this is not actually tendon but aponeurosis" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000045 name: ganglion namespace: uberon def: "A biological tissue mass, most commonly a mass of nerve cell bodies." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Ganglion] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "ganglia" RELATED [] synonym: "neural ganglion" RELATED [BTO:0000497] xref: AAO:0010426 xref: AEO:0000135 xref: BAMS:G xref: BTO:0000497 xref: CALOHA:TS-0397 xref: EFO:0000899 xref: EHDAA2:0003135 xref: EHDAA:2897 xref: EHDAA:4662 xref: EHDAA:5621 xref: EHDAA:918 xref: EMAPA:32846 xref: EV:0100372 xref: FMA:5884 xref: MA:0002406 xref: MAT:0000207 xref: MAT:0000343 xref: MESH:D005724 xref: MIAA:0000207 xref: MIAA:0000343 xref: NCIT:C12719 xref: NLXANAT:100302 xref: TAO:0000190 xref: TGMA:0001016 xref: UMLS:C0017067 {source="ncithesaurus:Ganglion"} xref: VHOG:0000156 xref: WBbt:0005189 xref: Wikipedia:Ganglion xref: XAO:0000209 xref: ZFA:0000190 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 {source="https://github.com/obophenotype/uberon/issues/2495#issuecomment-1187364719"} ! anatomical structure relationship: composed_primarily_of UBERON:0003714 {source="EHDAA2"} ! neural tissue relationship: develops_from UBERON:0003869 ! presumptive ganglion relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: immediate_transformation_of UBERON:0003869 {source="Bgee:AN"} ! presumptive ganglion relationship: part_of UBERON:0001016 ! nervous system property_value: editor_note "TODO - check vert vs invert. Other species: Any of a number of aggregations of neurons, glial cells and their processes, surrounded by a glial cell and connective tissue sheath (plural: ganglia). // Subdivision of neural tree (organ) which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord); together with a nucleus and its associated nerve, it constitutes a neural tree (organ). Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion. // a cluster of nerve cells and associated glial cells (nuclear location) // Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system." xsd:string property_value: UBPROP:0000001 "A ganglion is a cluster of neurons. It is part of a nervous system. It may include glial cells. The neurons are arranged in a specific constellation: neuronal somata are concentrated at the surface, thus forming a cell cortex, and neurites are concentrated in the centre of the ganglion to form the neuropil. A ganglion is a distinct unit but several ganglia may be anterio-posteriorly joined by connectives or transversally by commissures" xsd:string {source="PMID:21062451"} property_value: UBPROP:0000001 "Portion of tissue that contains cell bodies of neurons and is located outside the central nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010426", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Structures containing a collection of nerve cell bodies. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000190", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Subdivision of nervous system which primarily consists of cell bodies of neurons located outside the neuraxis (brain and spinal cord. Examples: spinal ganglion, trigeminal ganglion, superior cervical ganglion, celiac ganglion, inferior hypogastric (pelvic) ganglion (adapted from Foundational Model of Anatomy)[NLXANAT:100302]." xsd:string {source="NLXANAT:100302"} property_value: UBPROP:0000003 "Cranial sensory placodes are focused areas of the head ectoderm of vertebrates that contribute to the development of the cranial sense organs and their associated ganglia. Placodes have long been considered a key character of vertebrates, and their evolution is proposed to have been essential for the evolution of an active predatory lifestyle by early vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000156", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.021 Mazet F, Hutt JA, Milloz J, Millard J, Graham A, Shimeld SM, Molecular evidence from Ciona intestinalis for the evolutionary origin of vertebrate sensory placodes. Developmental Biology (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ganglionic" xsd:string [Term] id: UBERON:0000047 name: simple eye namespace: uberon def: "An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity." [Wikipedia:Eye#Simple_eyes] subset: grouping_class subset: uberon_slim xref: TGMA:0000729 xref: Wikipedia:Eye#Simple_eyes is_a: UBERON:0000970 ! eye [Term] id: UBERON:0000055 name: vessel namespace: uberon def: "A tubular structure that contains, conveys body fluid, such as blood or lymph." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: human_reference_atlas subset: pheno_slim is_a: UBERON:0004111 ! anatomical conduit relationship: channel_for UBERON:0006314 ! bodily fluid property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000056 name: ureter namespace: uberon def: "Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs." [GO:0090189, Wikipedia:Ureter] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "metanephric duct" RELATED [ISBN:0073040584, VHOG:0000605] xref: AAO:0010254 xref: BTO:0001409 xref: CALOHA:TS-1084 xref: EFO:0000930 xref: EHDAA2:0002139 xref: EHDAA:9341 xref: EMAPA:17950 xref: EV:0100097 xref: FMA:9704 xref: GAID:438 xref: galen:Ureter xref: MA:0000378 xref: MAT:0000120 xref: MESH:D014513 xref: MIAA:0000120 xref: NCIT:C12416 xref: SCTID:302511008 xref: UMLS:C0041951 {source="ncithesaurus:Ureter"} xref: VHOG:0000605 xref: Wikipedia:Ureter xref: XAO:0000144 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0006555 ! excretory tube is_a: UBERON:0015212 ! lateral structure relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0001224 ! renal pelvis relationship: channels_into UBERON:0001255 ! urinary bladder relationship: develops_from UBERON:0005081 {source="GO"} ! ureter ureteric bud relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism relationship: part_of UBERON:0036295 ! renal pelvis/ureter property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical structure consisting of long narrow duct which carries urine from the kidney to the urinary bladder.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010254", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The duct of amniotes that carries urine from a metanephric kidney to the urinary bladder. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000605", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ureteral" xsd:string property_value: UBPROP:0000007 "ureteric" xsd:string property_value: UBPROP:0000010 "in humans, consists of adventitial, muscular and mucoa layers" xsd:string [Term] id: UBERON:0000057 name: urethra namespace: uberon def: "The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening." [MGI:anna, MP:0000537] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim xref: BTO:0001426 xref: CALOHA:TS-1132 xref: EFO:0000931 xref: EMAPA:30901 xref: EV:0100099 xref: FMA:19667 xref: GAID:390 xref: galen:Urethra xref: MA:0000379 xref: MAT:0000121 xref: MESH:D014521 xref: MIAA:0000121 xref: NCIT:C12417 xref: SCTID:302513006 xref: UMLS:C0041967 {source="ncithesaurus:Urethra"} xref: VHOG:0001264 xref: Wikipedia:Urethra xref: XAO:0000153 is_a: UBERON:0000062 ! organ is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure relationship: capable_of_part_of GO:0060073 ! micturition relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0001255 ! urinary bladder relationship: continuous_with UBERON:0001255 ! urinary bladder relationship: develops_from UBERON:0000164 {notes="pelvic part of UG sinus gives rise to prostatic and membranous parts of urethra", source="Wikipedia"} ! primitive urogenital sinus relationship: develops_from UBERON:0013241 {source="Wikipedia"} ! embryonic urethral groove relationship: part_of UBERON:0001556 ! lower urinary tract property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI property_value: UBPROP:0000007 "urethral" xsd:string property_value: UBPROP:0000008 "In human males, the urethra travels through the penis, and carries semen as well as urine. In females, the urethra is shorter and emerges above the vaginal opening." xsd:string [Term] id: UBERON:0000058 name: duct namespace: uberon def: "A tubular structure that transports secreted or excreted substances." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm#ducts] subset: grouping_class synonym: "anatomical duct" EXACT [] synonym: "ducts" RELATED PLURAL [XAO:0004000] synonym: "exocrine duct" NARROW [] synonym: "exocrine gland duct" NARROW [] xref: AAO:0011123 xref: FBbt:00100314 xref: FMA:30320 xref: galen:Duct xref: NCIT:C12948 xref: SCTID:91726008 xref: TAO:0005171 xref: UMLS:C0687028 {source="ncithesaurus:Duct"} xref: Wikipedia:Duct_(anatomy) xref: XAO:0004000 xref: ZFA:0005171 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000063 ! organ subunit relationship: conduit_for UBERON:0000463 ! organism substance relationship: has_part UBERON:0034969 ! epithelial layer of duct relationship: has_quality PATO:0002299 ! tubular property_value: UBPROP:0000001 "A tube shaped portion of tissue lined with epithelial cells that collects secretions and routes them to their destination[ZFA:0005171]." xsd:string {source="ZFA:0005171"} property_value: UBPROP:0000012 "Most ducts, but not all, are exocrine gland ducts. Some ontologies classify structures such as the oviduct here." xsd:string [Term] id: UBERON:0000059 name: large intestine namespace: uberon def: "A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]." [ISBN:0073040584, Wikipedia:Large_intestine_(anatomy)] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim synonym: "intestinum crassum" RELATED [BTO:0000706] xref: AAO:0010396 xref: BTO:0000706 xref: CALOHA:TS-1306 xref: EFO:0000840 xref: EMAPA:19252 xref: EV:0100077 xref: FMA:7201 xref: GAID:306 xref: galen:LargeIntestine xref: MA:0000333 xref: MESH:D007420 xref: MIAA:0000046 xref: NCIT:C12379 xref: SCTID:181254001 xref: UMLS:C0021851 {source="ncithesaurus:Large_Intestine"} xref: VHOG:0000054 xref: Wikipedia:Large_intestine_(anatomy) xref: XAO:0000131 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract is_a: UBERON:0013765 ! digestive system element relationship: contributes_to_morphology_of UBERON:0000160 ! intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0004907 ! lower digestive tract property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Intestinal surface area also is increased in amphibians and reptiles by internal folds and occasionally by a few villi. The intestine can be divided into a small intestine and a slightly wider large intestine.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000054", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.566", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000060 name: anatomical wall namespace: uberon alt_id: UBERON:0009915 def: "Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers." [FMA:82482] subset: upper_level synonym: "organ wall" RELATED [FMA:82482] synonym: "wall" BROAD [] synonym: "wall of organ" EXACT [FMA:82482] xref: EMAPA:25036 xref: FMA:82482 xref: galen:Wall is_a: UBERON:0000064 ! organ part relationship: adjacent_to UBERON:0002553 ! anatomical cavity relationship: has_part UBERON:0004923 ! organ component layer property_value: UBPROP:0000012 "in FMA, serosa is a wall" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000061 name: anatomical structure namespace: uberon def: "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." [CARO:0000003] subset: common_anatomy subset: upper_level synonym: "biological structure" EXACT [] synonym: "connected biological structure" EXACT [CARO:0000003] xref: AAO:0010825 xref: AEO:0000003 xref: BILA:0000003 xref: CARO:0000003 xref: EHDAA2:0003003 xref: EMAPA:0 xref: FBbt:00007001 xref: FMA:305751 xref: FMA:67135 xref: GAID:781 xref: HAO:0000003 xref: http://dbpedia.org/ontology/AnatomicalStructure xref: MA:0003000 xref: MESH:D000825 xref: SCTID:362889002 xref: TAO:0000037 xref: TGMA:0001823 xref: VHOG:0001759 xref: XAO:0003000 xref: ZFA:0000037 is_a: UBERON:0000465 ! material anatomical entity relationship: existence_ends_during_or_before UBERON:0000071 ! death stage relationship: existence_starts_during_or_after UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000062 name: organ namespace: uberon def: "Anatomical structure that performs a specific function or group of functions [WP]." [Wikipedia:Organ_(anatomy)] subset: common_anatomy subset: upper_level synonym: "anatomical unit" RELATED [] synonym: "body organ" RELATED [] synonym: "element" RELATED [http://orcid.org/0000-0002-6601-2165] xref: BIRNLEX:4 xref: CARO:0020004 xref: EFO:0000634 xref: EMAPA:35949 xref: ENVO:01000162 xref: FMA:67498 xref: MA:0003001 xref: NCIT:C13018 xref: SCTID:272625005 xref: UMLS:C0178784 {source="ncithesaurus:Organ"} xref: WBbt:0003760 xref: Wikipedia:Organ_(anatomy) is_a: UBERON:0010000 ! multicellular anatomical structure disjoint_from: UBERON:0002095 {source="PMID:28192867"} ! mesentery disjoint_from: UBERON:0034921 ! multi organ part structure relationship: capable_of GO:0008150 ! biological_process relationship: existence_starts_during_or_after UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! organogenesis stage relationship: has_boundary UBERON:0006984 ! anatomical surface relationship: part_of UBERON:0000467 ! anatomical system property_value: RO:0002161 NCBITaxon:110815 {source="Wikipedia"} property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000001 "Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." xsd:string {source="GO:0048513"} property_value: UBPROP:0000012 "CARO v1 does not include a generic 'organ' class, only simple and compound organ. CARO v2 may include organ, see https://github.com/obophenotype/caro/issues/4" xsd:string [Term] id: UBERON:0000063 name: organ subunit namespace: uberon def: "A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity." [http://orcid.org/0000-0002-6601-2165] subset: upper_level synonym: "organ region with fixed fiat boundary" RELATED [FMA:86140] synonym: "organ segment" RELATED [FMA:86140] synonym: "segment of organ" RELATED [FMA:86140] xref: FMA:86140 is_a: UBERON:0000064 ! organ part property_value: editor_note "FMA distinguishes segment from zone by whether the fiat boundaries are fixed/anchored (segments) or floating (zone). It's not completely clear how to apply this distinction" xsd:string property_value: UBPROP:0000001 "Organ region with one or more anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball." xsd:string {source="FMA:86140", version="3"} property_value: UBPROP:0000001 "Organ region with one or more fixed or anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyebal." xsd:string {source="FMA:86140", version="1"} [Term] id: UBERON:0000064 name: organ part namespace: uberon def: "A multicellular structure that is a part of an organ." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: efo_slim subset: non_informative subset: upper_level synonym: "cardinal organ part" EXACT [FMA:82472] synonym: "regional part of organ" RELATED [BIRNLEX:16] xref: AAO:0011124 xref: BIRNLEX:16 xref: EFO:0000635 xref: FMA:82472 xref: SCTID:113343008 xref: SCTID:91717005 is_a: UBERON:0010000 ! multicellular anatomical structure relationship: part_of UBERON:0000062 ! organ property_value: IAO:0000232 "currently defined in a very broad sense, may be replaced by more specific classes in the future" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000065 name: respiratory tract namespace: uberon def: "Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas xref: EHDAA2:0001606 xref: EHDAA:1568 xref: EHDAA:2219 xref: EMAPA:16737 xref: FMA:265130 xref: SCTID:361110005 xref: VHOG:0000393 is_a: UBERON:0001005 ! respiratory airway is_a: UBERON:0004119 ! endoderm-derived structure relationship: develops_from UBERON:0007026 {source="NCBIBook:NBK10107"} ! presumptive gut relationship: develops_from UBERON:0008947 ! respiratory primordium property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000066 name: fully formed stage namespace: uberon def: "The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "adult stage" BROAD [] synonym: "fully formed animal stage" EXACT [] synonym: "juvenile-adult stage" EXACT [] xref: BilaDO:0000004 xref: BTO:0001043 xref: EFO:0001272 xref: FBdv:00005369 xref: WBls:0000041 xref: XtroDO:0000084 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000092 ! post-embryonic stage relationship: preceded_by UBERON:0000111 ! organogenesis stage relationship: preceded_by UBERON:0004729 {gci_relation="part_of", gci_filler="NCBITaxon:6239"} ! nematode larval stage relationship: precedes UBERON:0000071 ! death stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/566" xsd:anyURI [Term] id: UBERON:0000068 name: embryo stage namespace: uberon def: "A life cycle stage that starts with fertilization and ends with the fully formed embryo." [http://orcid.org/0000-0002-6601-2165] synonym: "embryogenesis" RELATED [] synonym: "embryonic stage" EXACT [] xref: BilaDO:0000002 xref: EV:0300001 xref: FBdv:00005289 xref: FMA:72652 xref: HsapDv:0000002 xref: MmusDv:0000002 xref: OGES:000000 xref: OGES:000022 xref: SCTID:296280003 xref: WBls:0000003 xref: WBls:0000092 xref: WBls:0000102 xref: XAO:1000012 is_a: UBERON:0000105 ! life cycle stage disjoint_from: UBERON:0000092 ! post-embryonic stage relationship: precedes UBERON:0000066 ! fully formed stage relationship: precedes UBERON:0000092 ! post-embryonic stage relationship: simultaneous_with GO:0009790 ! embryo development [Term] id: UBERON:0000069 name: larval stage namespace: uberon def: "A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva] subset: efo_slim synonym: "ammocoete" NARROW SENSU [Wikipedia:Larva] synonym: "ammocoete stage" NARROW SENSU [Wikipedia:Larva] synonym: "bipinnaria" NARROW SENSU [Wikipedia:Larva] synonym: "bipinnaria stage" NARROW SENSU [Wikipedia:Larva] synonym: "caterpillar" NARROW SENSU [Wikipedia:Larva] synonym: "caterpillar stage" NARROW SENSU [Wikipedia:Larva] synonym: "glochidium" NARROW SENSU [Wikipedia:Larva] synonym: "glochidium stage" NARROW SENSU [Wikipedia:Larva] synonym: "grub" NARROW SENSU [Wikipedia:Larva] synonym: "grub stage" NARROW SENSU [Wikipedia:Larva] synonym: "larva" RELATED [] synonym: "larva stage" EXACT [] synonym: "leptocephalus" NARROW SENSU [Wikipedia:Larva] synonym: "leptocephalus stage" NARROW SENSU [Wikipedia:Larva] synonym: "maggot" NARROW SENSU [Wikipedia:Larva] synonym: "maggot stage" NARROW SENSU [Wikipedia:Larva] synonym: "metacestode" NARROW SENSU [BTO:0000859] synonym: "naiad, nymph" NARROW SENSU [Wikipedia:Larva] synonym: "naiad, nymph stage" NARROW SENSU [Wikipedia:Larva] synonym: "nauplius" NARROW SENSU [Wikipedia:Larva] synonym: "nauplius stage" NARROW SENSU [Wikipedia:Larva] synonym: "nymph" NARROW SENSU [Wikipedia:Larva] synonym: "nymph stage" NARROW SENSU [Wikipedia:Larva] synonym: "planula" NARROW SENSU [Wikipedia:Larva] synonym: "planula stage" NARROW SENSU [Wikipedia:Larva] synonym: "tornaria" NARROW SENSU [NCBITaxon:10219] synonym: "trochophore" NARROW SENSU [Wikipedia:Larva] synonym: "trochophore stage" NARROW SENSU [Wikipedia:Larva] synonym: "veliger" NARROW SENSU [Wikipedia:Larva] synonym: "veliger stage" NARROW SENSU [Wikipedia:Larva] synonym: "wriggler" NARROW SENSU [Wikipedia:Larva] synonym: "wriggler stage" NARROW SENSU [Wikipedia:Larva] synonym: "zoea" NARROW SENSU [Wikipedia:Larva] synonym: "zoea stage" NARROW SENSU [Wikipedia:Larva] xref: BTO:0000915 xref: BTO:0000954 xref: EFO:0001303 xref: FBdv:00005336 xref: MIAA:0000400 xref: OGES:000008 xref: Wikipedia:Larva xref: ZFS:0000048 is_a: UBERON:0000105 ! life cycle stage relationship: immediately_preceded_by UBERON:0000068 ! embryo stage relationship: part_of UBERON:0000092 ! post-embryonic stage relationship: simultaneous_with GO:0002164 ! larval development property_value: IAO:0000232 "Uberon includes clade-specific subclasses, e.g. nematod larva" xsd:string property_value: RO:0002161 NCBITaxon:32524 property_value: UBPROP:0000008 "It is a misunderstanding that the larval form always reflects the group's evolutionary history. It could be the case, but often the larval stage has evolved secondarily, as in insects. In these cases the larval form might differ more from the group's common origin than the adult form" xsd:string {source="WP"} [Term] id: UBERON:0000071 name: death stage namespace: uberon def: "End of the life of an organism." [XAO:0000437] subset: common_anatomy synonym: "death" RELATED [] xref: XAO:0000437 xref: XtroDO:0000085 is_a: UBERON:0000105 ! life cycle stage relationship: ends UBERON:0000104 ! life cycle property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000012 "ncit:Death is an outcome" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0000072 name: proximo-distal subdivision of respiratory tract namespace: uberon def: "An section of a respiratory tract." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "respiratory tract" RELATED [MA:0000434] synonym: "subdivision of respiratory tract" RELATED [] xref: EMAPA:16737 xref: FMA:45660 xref: MA:0000434 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: part_of UBERON:0000065 ! respiratory tract property_value: UBPROP:0000012 "MA:0000434 has subclasses upper and lower, so it corresponds to a segment of the tract, rather than the tract as a whole" xsd:string {external_ontology="MA"} [Term] id: UBERON:0000073 name: regional part of nervous system namespace: uberon def: "Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS." [BIRNLEX:1157] subset: non_informative subset: upper_level synonym: "part of nervous system" EXACT [BIRNLEX:1157] xref: BIRNLEX:1157 xref: NCIT:C13040 xref: SCTID:25087005 xref: UMLS:C1518256 {source="ncithesaurus:Nervous_System_Part"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000481 ! multi-tissue structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0001016 ! nervous system relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001016 ! nervous system creation_date: 2009-06-18T09:00:04Z [Term] id: UBERON:0000075 name: subdivision of skeletal system namespace: uberon alt_id: UBERON:0010322 def: "Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: non_informative synonym: "skeletal system part" RELATED [] synonym: "skeletal system subdivision" EXACT [FMA:85544] xref: FMA:85544 xref: galen:ComplexSkeletalStructure xref: NCIT:C34076 xref: SCTID:118966000 xref: UMLS:C1519343 {source="ncithesaurus:Skeletal_System_Part"} is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: composed_primarily_of UBERON:0004765 ! skeletal element relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0001434 ! skeletal system [Term] id: UBERON:0000076 name: external ectoderm namespace: uberon def: "The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm." [MGI:anna, MP:0012532] subset: pheno_slim synonym: "surface (external) ectoderm" EXACT [] synonym: "surface ectoderm" EXACT [MP:0012532] xref: EHDAA2:0001968 xref: EHDAA:1494 xref: EHDAA:350 xref: EHDAA:4784 xref: EHDAA:4790 xref: EHDAA:4796 xref: EHDAA:7860 xref: EMAPA:16096 xref: FMA:87656 xref: NCIT:C34309 xref: UMLS:C1515087 {source="ncithesaurus:Surface_Ectoderm"} xref: Wikipedia:External_ectoderm is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0000924 {source="EHDAA2"} ! ectoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1d/Ectoderm.png" xsd:anyURI property_value: editor_note "merge with non-neural. In vertebrates, the ectoderm has three parts: external ectoderm (also known as surface ectoderm), the neurectoderm (neural crest, and neural tube)" xsd:string property_value: RO:0002171 UBERON:0002346 property_value: UBPROP:0000011 "(or external ectoderm) forms the following structures: Skin Epithelium of the mouth and nasal cavity saliavary glands, and glands of mouth and nasal cavity Enamel - as a side note dentin and dental pulp are formed from ectomesenchyme which is derived from ectoderm Epithelium of pineal and pituitary glands Lens and cornea of the eye Apical ectodermal ridge inducing development of the limb buds of the embryo. Sensory receptors in epidermis" xsd:string [Term] id: UBERON:0000077 name: mixed endoderm/mesoderm-derived structure namespace: uberon def: "An anatomical structure that develops from the endoderm and the mesoderm." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: develops_from UBERON:0000926 ! mesoderm property_value: IAO:0000232 "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string [Term] id: UBERON:0000078 name: mixed ectoderm/mesoderm/endoderm-derived structure namespace: uberon def: "An anatomical structure that develops from the ectoderm, mesoderm and endoderm." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000924 ! ectoderm intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: develops_from UBERON:0000926 ! mesoderm property_value: IAO:0000232 "Grouping term for query purposes. Notes that the developmental relationships are being refined such that most structures should develop in whole from at most one layer, but may have contributions from multiple" xsd:string [Term] id: UBERON:0000079 name: male reproductive system namespace: uberon def: "The organs associated with producing offspring in the gender that produces spermatozoa." [MP:0001145] subset: efo_slim subset: pheno_slim synonym: "genitalia of male organism" EXACT [OBOL:automatic] synonym: "male genital organ" RELATED [BTO:0000082] synonym: "male genital system" EXACT [FMA:45664] synonym: "male genital tract" RELATED [] synonym: "male genitalia" EXACT [] synonym: "male genitals" EXACT [] synonym: "male organism genitalia" EXACT [OBOL:automatic] synonym: "male organism reproductive system" EXACT [OBOL:automatic] synonym: "male reproductive tract" RELATED [MA:0000396] synonym: "reproductive system of male organism" EXACT [OBOL:automatic] synonym: "systema genitale masculinum" RELATED [BTO:0000082] xref: BTO:0000082 xref: CALOHA:TS-1310 xref: EFO:0000970 xref: EHDAA2:0001054 xref: EHDAA:8136 xref: EMAPA:17968 xref: EV:0100101 xref: FBbt:00004927 xref: FMA:45664 xref: GAID:386 xref: HAO:0000505 xref: MA:0000396 xref: MESH:D005837 xref: NCIT:C12722 xref: SCTID:361340001 xref: TGMA:0000634 xref: UMLS:C0017422 {source="ncithesaurus:Male_Genitalia"} xref: UMLS:C1963704 {source="ncithesaurus:Male_Reproductive_System"} xref: VHOG:0000725 xref: Wikipedia:Male_reproductive_system_(human) xref: XAO:0000155 is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003101 ! male organism disjoint_from: UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0003101 ! male organism property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000725", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000080 name: mesonephros namespace: uberon def: "The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo." [GO:0001823, Wikipedia:Mesonephros] subset: efo_slim subset: organ_slim subset: pheno_slim subset: vertebrate_core synonym: "amphibian adult kidney" RELATED [XAO:0000141] synonym: "corpus Wolffi" RELATED [BTO:0001542] synonym: "mesonephric kidney" EXACT [XAO:0000141] synonym: "mesonephroi" EXACT PLURAL [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "middle kidney" RELATED [BTO:0001542] synonym: "opisthonephros" RELATED [VHOG:0000038, XAO:0000141] synonym: "opisto nephros" RELATED [] synonym: "opistonephros" RELATED [http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html] synonym: "Wolffian body" EXACT [BTO:0001542, GOC:yaf, MESH:A16.254.500, Wikipedia:Mesonephros] xref: AAO:0010384 xref: BTO:0001542 xref: CALOHA:TS-0624 xref: EFO:0000928 xref: EHDAA2:0001130 xref: EHDAA:1581 xref: EHDAA:5903 xref: EMAPA:16744 xref: FMA:72171 xref: GAID:1308 xref: MESH:D001755 xref: NCIT:C26467 xref: SCTID:308799002 xref: TAO:0000529 xref: UMLS:C0025492 {source="ncithesaurus:Mesonephros"} xref: VHOG:0000038 xref: Wikipedia:Mesonephros xref: XAO:0000141 xref: ZFA:0000529 is_a: UBERON:0002113 ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from UBERON:0002120 ! pronephros property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray986.png" xsd:anyURI property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the middle region of the nephric ridge; a transient embryonic stage that replaces the pronephros, but is itself replaced by the adult metanephros [in mammals; in fishes and amphibians it is the adult kidney]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Organ that is the definitive adult kidney. It replaces the earlier pronephros, which degenerates as the mesonephros becomes functional in feeding stage tadpoles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010384", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates. (...) In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000038", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "mesonephric" xsd:string property_value: UBPROP:0000008 "In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In fish and amphibians, the mesonephros will form the mature kidney" xsd:string property_value: UBPROP:0000009 "By contrast to the pronephros, the histological features of the mammalian mesonephros, with its primitive glomeruli, suggest that it probably functions as a primitive kidney, and is involved in the production of much of the amniotic fluid. Within the two mesonephroi, one located on either side of the dorsal mesentery of the hindgut, a substantial number (in the region of about 40 or more) of cranio-caudally segmented mesonephric tubules are formed. It has, however, been suggested that only the most rostrally located 4-6 pairs of mesonephric tubules drain into the mesonephric portion of the nephric duct. This is now seen to extend along the length of the mesonephroi, being located towards their lateral sides. The mesonephros is also retained over a considerably longer period than the pronephros, but gradually undergoes regression in a cranio-caudal direction. While the rostral part displays clear evidence of regression its more caudal part appears to display evidence of functional activity. Within the medial part of the mesonephros, vesicles are formed, although no glomeruli are formed there in this species. It is, however, difficult to believe that the relatively enormous mesonephroi do not have an excretory role in the mouse, only serving as a base for gonadal differentiation. In the human embryo, the medial part of the mesonephric tubules enlarges, become invaginated by capillaries, and form glomeruli. These then take on an excretory role. In the mouse, the mesonephric ducts appear to be patent throughout their length[GUDMAP, modified]" xsd:string [Term] id: UBERON:0000081 name: metanephros namespace: uberon def: "In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO]." [GO:0001656, Wikipedia:Metanephros#Metanephros] subset: organ_slim subset: pheno_slim synonym: "definite kidney" RELATED [BTO:0001543] synonym: "definitive kidney" RELATED [BTO:0001543] synonym: "hind kidney" RELATED [BTO:0001543] synonym: "metanephric kidney" RELATED [VHOG:0000039] synonym: "metanephron" EXACT [BTO:0001543] xref: BTO:0001543 xref: EHDAA2:0001137 xref: EHDAA:3089 xref: EHDAA:5911 xref: EMAPA:17373 xref: EMAPA_RETIRED:17207 xref: FMA:72172 xref: NCIT:C34209 xref: SCTID:308797000 xref: UMLS:C0231049 {source="ncithesaurus:Metanephros"} xref: VHOG:0000039 xref: Wikipedia:Metanephros#Metanephros is_a: UBERON:0002113 ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure relationship: developmentally_replaces UBERON:0000080 {source="ISBN:9780878932504"} ! mesonephros relationship: develops_from UBERON:0003220 {evidence="definitional"} ! metanephric mesenchyme relationship: develops_from UBERON:0005080 {source="GO"} ! metanephric ureteric bud relationship: develops_from UBERON:0005753 ! caudal part of nephrogenic cord relationship: existence_ends_during UBERON:0000066 ! fully formed stage property_value: editor_note "TODO check developmental relationships" xsd:string property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the posterior region of the nephric ridge and drained by a ureter; replaces the embryonic pronephros and mesonephros [in mammals]. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.745][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000039", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "metanephric" xsd:string property_value: UBPROP:0000011 "During the fifth week of gestation, the mesonephric duct develops an outpouching, the ureteric bud, near its attachment to the cloaca. This bud, also called the metanephrogenic diverticulum, grows posteriorly and towards the head of the embryo. The elongated stalk of the ureteric bud, the metanephric duct, later forms the ureter. As the cranial end of the bud extends into the intermediate mesoderm, it undergoes a series of branchings to form the collecting duct system of the kidney. It also forms the major and minor calyces and the renal pelvis" xsd:string [Term] id: UBERON:0000083 name: mesonephric tubule namespace: uberon def: "A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]." [Wikipedia:Mesonephric_tubules] synonym: "renal tubules" RELATED PLURAL [VHOG:0000500] synonym: "tubuli mesonephrici" RELATED LATIN [Wikipedia:Mesonephric_tubules] xref: AAO:0010389 xref: EHDAA2:0001134 xref: EMAPA:16747 xref: VHOG:0000500 xref: Wikipedia:Mesonephric_tubules xref: XAO:0000148 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005103 ! mesonephric epithelium is_a: UBERON:0006555 ! excretory tube intersection_of: UBERON:0003914 ! epithelial tube intersection_of: part_of UBERON:0000080 ! mesonephros property_value: editor_note "TODO check" xsd:string property_value: UBPROP:0000001 "Any of the renal tubules composing the mesonephros. In mammals they function as excretory structures during the early embryonic development but are later incorporated into the reproductive system. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesonephric+tubule"} property_value: UBPROP:0000003 "As the pronephros regresses, the archinephric duct induces the sequential differentiation of tubules in the more caudal parts of the nephric ridge. (...) Tubules that differentiate in the middle part of the nephric ridge form a kidney called the mesonephros. This kidney functions in the embryos and larvae of all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000500", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000084 name: ureteric bud namespace: uberon def: "An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP]." [MP:0010979, PMID:19828308] subset: pheno_slim synonym: "diverticulum" RELATED [BTO:0001646] synonym: "diverticulum metanephricum" RELATED LATIN [Wikipedia:Ureteric_bud] synonym: "gemma ureterica" RELATED LATIN [Wikipedia:Ureteric_bud] synonym: "metanephric bud" RELATED [BTO:0001646] synonym: "metanephric diverticulum" RELATED [Wikipedia:Metanephros#Metanephros] synonym: "ureteric ampulla" RELATED [] synonym: "ureteric diverticulum" RELATED [VHOG:0000541] xref: BTO:0001646 xref: EHDAA2:0002140 xref: EHDAA:3091 xref: EHDAA:5917 xref: EMAPA:17209 xref: NCIT:C34207 xref: SCTID:361528000 xref: UMLS:C1284058 {source="ncithesaurus:Metanephric_Diverticulum"} xref: VHOG:0000541 xref: Wikipedia:Ureteric_bud is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac is_a: UBERON:0034969 ! epithelial layer of duct relationship: developmentally_induced_by UBERON:0003220 {source="ISBN:9780878932504"} ! metanephric mesenchyme relationship: develops_from UBERON:0003074 {source="EHDAA2"} ! mesonephric duct relationship: part_of UBERON:0003074 ! mesonephric duct property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts. [Embryology, See_Dudek_RW_and_Fix_JD, Third_Edition_(2004)_Philadelphia:_Lippincott_William_and_Wilkins, p.137][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Outgrowth of the mesonephric duct that penetrates the metanephric mesoderm and forms the ureter, renal pelvis, major and minor calyces and collecting ducts[VHOG:0000541]." xsd:string {source="VHOG:0000541"} property_value: UBPROP:0000003 "The first embryonic hint of a metanephros is the formation of the metanephric duct that appears as a ureteric diverticulum arising at the base of preexisting mesonephric duct. The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes, and the metanephric duct is usually called the ureter.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000541", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000085 name: morula namespace: uberon def: "A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum." [MP:0012130] subset: pheno_slim synonym: "morula (2-16 cells)" RELATED [EHDAA2:0000005] xref: BTO:0001508 xref: EHDAA2:0000005 xref: FMA:292334 xref: GAID:1295 xref: MESH:D009028 xref: NCIT:C34212 xref: SCTID:361474003 xref: UMLS:C0026573 {source="ncithesaurus:Morula"} xref: Wikipedia:Morula is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000922 ! embryo relationship: existence_ends_during UBERON:0000107 ! cleavage stage relationship: existence_starts_during UBERON:0000107 ! cleavage stage relationship: has_part CL:0000353 ! blastoderm cell relationship: part_of UBERON:0004716 {source="EHDAA2"} ! conceptus relationship: surrounded_by UBERON:0000086 ! zona pellucida property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI property_value: UBPROP:0000012 "EHDAA2 has embryo starting later" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0000086 name: zona pellucida namespace: uberon def: "A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes." [Wikipedia:Zona_pellucida] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "oolemma" RELATED [BTO:0003135] synonym: "pellucid zone" RELATED [BTO:0003135] synonym: "striated membrane" RELATED [BTO:0003135] synonym: "vitelline envelope" RELATED [] synonym: "vitelline membrane" RELATED [] synonym: "zona pellucida - vitelline membrane" BROAD [VHOG:0000720] synonym: "zona radiata" RELATED [BTO:0003135] synonym: "zona striata" RELATED [BTO:0003135] xref: BTO:0003135 xref: EHDAA2:0002220 xref: EHDAA:31 xref: EHDAA:62 xref: EMAPA:16035 xref: FMA:18674 xref: GAID:410 xref: MA:0001715 xref: MESH:D015044 xref: NCIT:C33896 xref: TAO:0001111 xref: UMLS:C0043519 {source="ncithesaurus:Zona_Pellucida"} xref: VHOG:0000720 xref: Wikipedia:Zona_pellucida xref: ZFA:0001111 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0005764 ! acellular membrane relationship: bounding_layer_of CL:0000023 ! oocyte relationship: has_part CHEBI:17089 ! glycoprotein relationship: part_of CL:0000023 ! oocyte relationship: part_of UBERON:0000992 ! ovary property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray3.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Outside the plasma membrane, three envelopes surround the ovum. The first, the primary egg envelope, lies between the plasma membrane and the surrounding cells of the ovary. The most consistent component of this primary layer is the vitelline membrane, a transparent jacket of fibrous protein. In mammals, the homologous structure is called the zona pellucida.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000720", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.159", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000087 name: inner cell mass namespace: uberon def: "A mass of cells that develop into the body of the embryo and some extraembryonic tissues." [ISBN:0-683-40008-8, MGI:pvb] subset: early_development subset: efo_slim subset: pheno_slim synonym: "early embryoblast" RELATED [FMA:86557] synonym: "embryoblast" RELATED [] synonym: "embryoblastus; massa cellularis interna; pluriblastus senior" RELATED LATIN [Wikipedia:Inner_cell_mass] synonym: "ICM" RELATED [VHOG:0000742] synonym: "pluriblast" RELATED [] xref: EFO:0000547 xref: EHDAA2:0000830 xref: EHDAA:40 xref: EMAPA:16041 xref: FMA:86557 xref: NCIT:C13740 xref: SCTID:361456007 xref: UMLS:C1283994 {source="ncithesaurus:Inner_Cell_Mass"} xref: VHOG:0000742 xref: Wikipedia:Inner_cell_mass is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000358 {source="Wikipedia"} ! blastocyst relationship: surrounded_by UBERON:0000088 {source="Wikipedia"} ! trophoblast property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI property_value: UBPROP:0000001 "A group of cells found in the mammalian blastocyst that give rise to the embryo. [Biology_Online][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000742", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "A small sphere of cells known as the inner cell mass lies within the trophoblast (of all eutherian mammals).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000742", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.144", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "This structure forms in the earliest steps of development, before implantation into the endometrium of the uterus has occurred.The ICM lies within the blastocyst cavity and is entirely surrounded by the single layer of cells called trophoblast. [Wikipedia:Inner_cell_mass]" xsd:string [Term] id: UBERON:0000088 name: trophoblast namespace: uberon def: "The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta." [ISBN:0-683-40008-8, MP:0005031] comment: Aggregate of cells forming the outer layer of a blastocyst, which provide nutrients to the embryo and develop into a large part of the placenta. They are formed during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg. [Wikipedia:Trophoblast] subset: early_development subset: human_reference_atlas subset: pheno_slim synonym: "massa cellularis externa" RELATED LATIN [Wikipedia:Trophoblast] synonym: "trophoblast layer" EXACT [MP:0005031] synonym: "trophoblastus" RELATED LATIN [Wikipedia:Trophoblast] synonym: "trophoderm" RELATED [BTO:0001079] xref: BTO:0001079 xref: CALOHA:TS-1070 xref: EV:0100120 xref: FMA:83029 xref: GAID:1152 xref: MESH:D014327 xref: NCIT:C93292 xref: SCTID:362839005 xref: UMLS:C0041178 {source="ncithesaurus:Trophoblast"} xref: Wikipedia:Trophoblast is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: composed_primarily_of CL:0000351 ! trophoblast cell relationship: develops_from UBERON:0004345 {source="MP-def", source="PMID:19829370"} ! trophectoderm relationship: part_of UBERON:0000358 ! blastocyst property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta[MP]" xsd:string {date_retrieved="2012-08-23", external_class="MP:0005031", external_class_label="trophoblast layer", ontology="MP", source="ISBN:0-683-40008-8"} property_value: UBPROP:0000007 "trophoblastic" xsd:string property_value: UBPROP:0000011 "The postimplantation derivatives of the trophectoderm, which make up most of the fetal part of the placenta" xsd:string {source="PMID:19829370"} [Term] id: UBERON:0000091 name: bilaminar disc namespace: uberon def: "A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc." [MP:0003886] subset: early_development subset: pheno_slim synonym: "bilaminar disk" RELATED [Wikipedia:Bilaminar_disc] synonym: "bilaminary embryonic disc" EXACT [] synonym: "bilaminary germ disc" EXACT [ISBN:9780878932504] synonym: "embryonic disc" BROAD [MP:0003886] synonym: "embryonic shield" BROAD [MP:0003886] synonym: "germinal disc" BROAD [MP:0003886] synonym: "germinal disk" BROAD [MP:0003886] xref: FMA:293863 xref: NCIT:C34112 xref: UMLS:C1283997 {source="ncithesaurus:Bilaminar_Embryonic_Disc"} xref: Wikipedia:Bilaminar_disc is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png" xsd:anyURI [Term] id: UBERON:0000092 name: post-embryonic stage namespace: uberon def: "Stage succeeding embryo, including mature structure." [https://orcid.org/0000-0002-6601-2165] synonym: "post-hatching stage" NARROW [] synonym: "postembryonic" RELATED [] synonym: "postembryonic stage" EXACT [] xref: BilaDO:0000003 xref: OGES:000010 xref: OGES:000014 xref: OGES:000024 xref: WBls:0000022 xref: WBls:0000093 xref: WBls:0000103 is_a: UBERON:0000105 ! life cycle stage relationship: preceded_by UBERON:0000068 ! embryo stage relationship: simultaneous_with GO:0009791 ! post-embryonic development property_value: seeAlso "https://github.com/obophenotype/uberon/issues/344" xsd:anyURI property_value: UBPROP:0000008 "In birds, the postnatal stage begins when the beak penetrates the shell (i.e., external pipping) (Brown et al. 1997)" xsd:string [Term] id: UBERON:0000093 name: sulcus namespace: uberon def: "A depression or fissure in the surface of an organ." [Wikipedia:Sulcus_(anatomy)] subset: grouping_class subset: non_informative xref: Wikipedia:Sulcus_(anatomy) is_a: UBERON:0000464 ! anatomical space relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 creation_date: 2009-04-09T06:23:22Z [Term] id: UBERON:0000094 name: membrane organ namespace: uberon def: "Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]." [FMA:7145] synonym: "membrane" BROAD [] synonym: "membrane of organ" EXACT [] xref: FMA:7145 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000062 ! organ relationship: composed_primarily_of UBERON:0011823 {source="FMA-def"} ! dense connective tissue relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 creation_date: 2009-07-30T05:19:13Z [Term] id: UBERON:0000095 name: cardiac neural crest namespace: uberon def: "Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]." [Wikipedia:Cardiac_neural_crest] subset: vertebrate_core synonym: "cardiac neural crest complex" RELATED [Wikipedia:Cardiac_neural_crest] synonym: "complexus cristae neuralis cardiacus" RELATED [Wikipedia:Cardiac_neural_crest] xref: TAO:0002173 xref: Wikipedia:Cardiac_neural_crest xref: XAO:0004190 xref: ZFA:0001648 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 relationship: overlaps UBERON:0005428 {source="Wikipedia"} ! vagal neural crest relationship: part_of UBERON:0002342 ! neural crest property_value: UBPROP:0000001 "A subpopulation of the cephalic neural crest that emerges from the otic level to the anterior limit of somite 4. It migrates to the heart and is essential for the septation of the outflow track[DOI:10.1242/dev.091751]." xsd:string {source="DOI:10.1242/dev.091751"} property_value: UBPROP:0000012 "ZFA treats this as a subtype of NC." xsd:string {external_ontology="ZFA"} creation_date: 2009-07-30T07:57:38Z [Term] id: UBERON:0000102 name: lung vasculature namespace: uberon def: "The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]." [GOC:GO] subset: pheno_slim synonym: "lung vascular network" EXACT [OBOL:automatic] synonym: "pulmonary vasculature" EXACT [FMA:73750] synonym: "vascular network of lung" EXACT [OBOL:automatic] synonym: "vasculature of lung" EXACT [OBOL:automatic] xref: FMA:73750 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0000104 name: life cycle namespace: uberon def: "An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism." [https://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: upper_level synonym: "entire life cycle" EXACT [] synonym: "entire lifespan" EXACT [] synonym: "life" EXACT [] synonym: "lifespan" EXACT [] xref: FBdv:00000000 xref: HsapDv:0000001 xref: MmusDv:0000001 xref: ncithesaurus:Life xref: OGES:000011 is_a: UBERON:0000000 ! processual entity relationship: ends_with UBERON:0000071 ! death stage relationship: has_part UBERON:0000105 ! life cycle stage relationship: starts_with UBERON:0000106 {gci_relation="in_taxon", gci_filler="NCBITaxon:33208"} ! zygote stage property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/532" xsd:anyURI [Term] id: UBERON:0000105 name: life cycle stage namespace: uberon def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [https://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: efo_slim subset: upper_level synonym: "developmental stage" NARROW [] synonym: "stage" NARROW [] xref: BILS:0000105 xref: EFO:0000399 xref: FBdv:00007012 xref: FMA:24120 xref: HsapDv:0000000 xref: MESH:D008018 xref: MmusDv:0000000 xref: ncithesaurus:Developmental_Stage xref: OlatDv:0000010 xref: PdumDv:0000090 xref: WBls:0000002 xref: XAO:1000000 xref: ZFS:0000000 xref: ZFS:0100000 is_a: UBERON:0000000 ! processual entity relationship: part_of UBERON:0000104 ! life cycle property_value: editor_note "this class represents a proper part of the life cycle of an organism. The class 'life cycle' should not be placed here" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000012 "the WBls class 'all stages' belongs here as it is the superclass of other WBls stages" xsd:string property_value: UBPROP:0000012 "we map the ZFS unknown stage here as it is logically equivalent to saying *some* life cycle stage" xsd:string [Term] id: UBERON:0000106 name: zygote stage namespace: uberon def: "A stage at which the organism is a single cell produced by means of sexual reproduction." [Wikipedia:Zygote] subset: efo_slim synonym: "1-cell stage" EXACT [] synonym: "fertilized egg stage" EXACT [BTO:0000854] synonym: "fertilized egg stage" RELATED [] synonym: "one cell stage" EXACT [] synonym: "one-cell stage" RELATED [VHOG:0000745] synonym: "zygote" RELATED [VHOG:0000745] synonym: "zygotum" RELATED LATIN [Wikipedia:Zygote] xref: BilaDO:0000005 xref: BILS:0000106 xref: EFO:0001322 xref: EHDAA:27 xref: FBdv:00005288 xref: NCIT:C12601 xref: PdumDv:0000100 xref: VHOG:0000745 xref: Wikipedia:Zygote xref: XAO:1000001 xref: ZFS:0000001 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: starts UBERON:0000104 ! life cycle property_value: seeAlso EMAPA:16033 property_value: UBPROP:0000003 "As in all metazoans, eumetazoan development begins with a fertilized egg, or zygote.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000745", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.107", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000107 name: cleavage stage namespace: uberon def: "The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula." [GO:0040016, Wikipedia:Cleavage_(embryo)] subset: efo_slim xref: BilaDO:0000006 xref: BILS:0000107 xref: EFO:0001290 xref: FBdv:00000054 xref: MESH:D002970 xref: MmusDv:0000004 xref: OGES:000015 xref: OGES:000020 xref: PdumDv:0000200 xref: Wikipedia:Cleavage_(embryo) xref: XAO:1000004 xref: ZFS:0000046 is_a: UBERON:0000105 ! life cycle stage intersection_of: UBERON:0000105 ! life cycle stage intersection_of: simultaneous_with GO:0040016 ! embryonic cleavage relationship: immediately_preceded_by UBERON:0000106 ! zygote stage relationship: part_of UBERON:0000068 ! embryo stage relationship: simultaneous_with GO:0040016 ! embryonic cleavage [Term] id: UBERON:0000108 name: blastula stage namespace: uberon def: "An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] subset: efo_slim xref: BilaDO:0000007 xref: BILS:0000108 xref: EFO:0001282 xref: HsapDv:0000006 xref: MmusDv:0000007 xref: OGES:000003 xref: OGES:000016 xref: OGES:000021 xref: WBls:0000005 xref: Wikipedia:Blastula xref: XAO:1000003 xref: ZFS:0000045 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000107 ! cleavage stage property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI property_value: editor_note "consider adding a preceding stage 'morula stage' as part of cleavage" xsd:string [Term] id: UBERON:0000109 name: gastrula stage namespace: uberon def: "A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." [GO:0007369] subset: efo_slim synonym: "blastocystis trilaminaris stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastocyst stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastoderm stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar disk stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ stage" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar stage" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BilaDO:0000008 xref: BILS:0000109 xref: EFO:0001296 xref: FBdv:00005317 xref: HsapDv:0000010 xref: MmusDv:0000013 xref: OGES:000004 xref: OGES:000019 xref: WBls:0000010 xref: XAO:1000005 xref: ZFS:0000047 is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000108 {source="BILS"} ! blastula stage relationship: simultaneous_with GO:0007369 ! gastrulation [Term] id: UBERON:0000110 name: neurula stage namespace: uberon def: "Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." [GO:0001841] xref: BilaDO:0000009 xref: BILS:0000110 xref: HsapDv:0000012 xref: MmusDv:0000017 xref: XAO:1000006 is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000109 ! gastrula stage relationship: simultaneous_with GO:0001841 ! neural tube formation property_value: seeAlso "https://github.com/obophenotype/uberon/issues/343" xsd:anyURI [Term] id: UBERON:0000111 name: organogenesis stage namespace: uberon def: "A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [Wikipedia:Organogenesis] synonym: "segmentation stage" RELATED [] xref: BilaDO:0000010 xref: BILS:0000111 xref: HsapDv:0000015 xref: MmusDv:0000018 xref: OGES:000005 xref: OGES:000032 xref: Wikipedia:Organogenesis is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000110 ! neurula stage relationship: simultaneous_with GO:0048513 ! animal organ development property_value: seeAlso "https://github.com/obophenotype/uberon/issues/533" xsd:anyURI [Term] id: UBERON:0000112 name: sexually immature stage namespace: uberon subset: efo_slim synonym: "immature stage" EXACT [VHOG:FB] synonym: "juvenile stage" NARROW [XAO:1000010] synonym: "subadult stage" RELATED [http://eol.org/schema/terms/subadult] xref: BILS:0000112 xref: BTO:0002168 xref: EFO:0001300 xref: EV:0300051 xref: MmusDv:0000043 xref: OGES:000009 xref: XAO:1000010 xref: XtroDO:0000083 xref: ZFS:0000051 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000066 ! fully formed stage relationship: preceded_by UBERON:0000069 {gci_relation="part_of", gci_filler="NCBITaxon:7955", source="ZFS"} ! larval stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/427" xsd:anyURI property_value: UBPROP:0000001 "The stage of being a sexually immature adult animal[XAO:1000010]." xsd:string {source="XAO:1000010"} property_value: UBPROP:0000008 "In mammals this would include infant (nourishment from lactation) and juvenile (prepubertal no longer dependent on mother)" xsd:string [Term] id: UBERON:0000113 name: post-juvenile adult stage namespace: uberon def: "The stage of being a sexually mature adult animal." [https://orcid.org/0000-0002-6601-2165] synonym: "adult stage" BROAD [] xref: BILS:0000113 xref: EV:0300064 xref: EV:0300070 xref: MIAA:0000403 xref: MmusDv:0000110 xref: OGES:000026 xref: OGES:000027 xref: XAO:1000093 xref: ZFS:0000044 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000066 ! fully formed stage relationship: preceded_by UBERON:0000112 ! sexually immature stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/345" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/499" xsd:anyURI [Term] id: UBERON:0000114 name: lung connective tissue namespace: uberon def: "The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin." [ISBN:0-683-40008-8, MGI:anna, MP:0002276, PMID:14635660] subset: human_reference_atlas subset: pheno_slim synonym: "connective tissue of lung" EXACT [OBOL:automatic] synonym: "lung interstitial tissue" RELATED [MA:0001782] synonym: "lung interstitium" RELATED [] synonym: "pulmonary connective tissue" RELATED [EMAPA:35521] synonym: "pulmonary interstitial tissue" RELATED [] synonym: "pulmonary interstitium" EXACT [FMA:27533] xref: EMAPA:35521 xref: FMA:27533 xref: MA:0001782 xref: SCTID:201609008 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003580 ! lower respiratory tract connective tissue is_a: UBERON:0003837 ! thoracic segment connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002048 ! lung relationship: contributes_to_morphology_of UBERON:0002048 ! lung relationship: develops_from UBERON:0004883 ! lung mesenchyme relationship: part_of UBERON:0002048 ! lung relationship: transformation_of UBERON:0004883 ! lung mesenchyme property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000009 "it functions in the mechanical behavior of the lung, and forms a barrier to regulate the flow of plasma constituents from the capillaries to the airway and alveolar spaces" xsd:string [Term] id: UBERON:0000115 name: lung epithelium namespace: uberon def: "The epithelial layer of the lung." [MP:0006382] subset: pheno_slim synonym: "epithelial tissue of lung" EXACT [OBOL:automatic] synonym: "epithelium of lung" EXACT [OBOL:automatic] synonym: "lung epithelial tissue" EXACT [OBOL:automatic] synonym: "pulmonary epithelium" RELATED [BTO:0001653] xref: BTO:0001653 xref: EMAPA:32860 xref: MA:0001783 is_a: UBERON:0004815 ! lower respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002048 ! lung relationship: contributes_to_morphology_of UBERON:0002048 ! lung relationship: develops_from UBERON:0001041 ! foregut relationship: part_of UBERON:0002048 ! lung property_value: UBPROP:0000008 "A pseudostratified epithelium, containing basal cells, stem cells of the airway, submucosal glands and cartilage rings, is limited to the trachea and large lobar airways in the mouse (Morrisey and Hogan, 2010). This more complex epithelium extends to terminal bronchioles in the human[DOI:10.1242/dev.115469]" xsd:string [Term] id: UBERON:0000117 name: respiratory tube namespace: uberon def: "A tube in the respiratory system. Examples: bronchus, bronchiole, trachea." [GO:0030323, http://orcid.org/0000-0002-6601-2165] synonym: "airway" RELATED [] synonym: "respiratory conducting tube" NARROW [MP:0004391] synonym: "segment of tracheobronchial tree" EXACT [FMA:12224] synonym: "segment of tracheobronchial tree" NARROW [FMA:12224] synonym: "tracheobronchial tree segment" NARROW [FMA:12224] xref: EMAPA:37946 {source="MA:th"} xref: FMA:12224 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000025 ! tube is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000025 ! tube intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: has_part UBERON:0000483 ! epithelium relationship: part_of UBERON:0000065 ! respiratory tract property_value: UBPROP:0000012 "in GO lung development is part of respiratory tube development. This can lead to inconsistencies with other ontologies, e.g. VT. The GO structure may be better represented by a tree of tubes (see the FMA class)" xsd:string {external_ontology="GO"} [Term] id: UBERON:0000118 name: lung bud namespace: uberon def: "Structure derived from foregut that becomes a lung[GO]." [GO:0060431, Wikipedia:Respiratory_bud] subset: pheno_slim synonym: "gemma pulmonalis" RELATED LATIN [Wikipedia:Lung_buds] synonym: "gemma respiratoria" RELATED LATIN [Wikipedia:Lung_buds] synonym: "lung bud" RELATED PLURAL [] synonym: "primary lung bud" RELATED [GO:0060572] synonym: "respiratory diverticulum" RELATED [Wikipedia:Lung_buds] xref: BTO:0001643 xref: EHDAA2:0004089 xref: NCIT:C34260 xref: NCIT:C34282 xref: SCTID:361427007 xref: UMLS:C1514420 {source="ncithesaurus:Primary_Bronchial_Bud"} xref: UMLS:C1514897 {source="ncithesaurus:Respiratory_Diverticulum"} xref: Wikipedia:Respiratory_bud is_a: UBERON:0005153 {source="GO:0060441"} ! epithelial bud is_a: UBERON:0005911 ! endo-epithelium relationship: adjacent_to UBERON:0004872 ! splanchnic layer of lateral plate mesoderm relationship: develops_from UBERON:0005597 ! lung primordium relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/71/Gray948.png" xsd:anyURI property_value: editor_note "clarify successors - include bronchi?" xsd:string [Term] id: UBERON:0000122 name: neuron projection bundle namespace: uberon alt_id: UBERON:0005163 def: "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." [CARO:0001001, FBbt:00005099, FBC:DOS] synonym: "funiculus" EXACT [] synonym: "nerve fiber bundle" EXACT [FBbt:00005099] synonym: "neural fiber bundle" EXACT [] xref: CARO:0001001 xref: FBbt:00005099 xref: NLX:147821 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005162 ! multi cell part structure relationship: has_part GO:0043005 ! neuron projection relationship: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0000125 name: neural nucleus namespace: uberon def: "A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO)." [NLX:28443] subset: cumbo synonym: "nervous system nucleus" EXACT [] synonym: "neuraxis nucleus" EXACT [FMA:83686] synonym: "neuronal nucleus" EXACT [AEO:0000136] synonym: "nucleus" BROAD [] synonym: "nucleus of CNS" EXACT [NLX:28443] synonym: "nucleus of neuraxis" RELATED [] xref: AEO:0000136 xref: FMA:83686 xref: NCIT:C13197 xref: NLX:28443 xref: Wikipedia:Nucleus_(neuroanatomy) is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: composed_primarily_of UBERON:0002020 ! gray matter relationship: only_in_taxon NCBITaxon:7711 {notes="we limit this structure by definition to chordate and vertebrate nervous systems"} ! Chordata property_value: UBPROP:0000001 "Anatomical structure consisting of a discrete aggregate of neuronal soma[GO][GO_REF:0000021]." xsd:string {source="GO_REF:0000021"} property_value: UBPROP:0000012 "Proposed CUMBO def from MM: A subcortical part of the nervous system consisting of a relatively compact group of cells that is distinguishable histologically that share a commonality of cytoarchitecture, chemoarchitecturel and connectivity. (comments: I put in 'subcortical' because I don't think we consider either the cerebellar cortex or cerebral cortex to be nuclei. Some people distinguish between a nucleus and a laminar structure (see Wikipedia definition). However, there are structures identified as nuclei that are laminar, e.g., lateral geniculate nucleus, although they are not laminated in all species. Also, I put in 'relatively compact' and 'distiguishable by histology' because we have groups of cells, e.g., cholinergic cell groups, doparminergic cell groups that are related on the 3 criteria but which we don't tend to consider nuclei because they don't occupy an easily defined territory. But all is open to debate." xsd:string [Term] id: UBERON:0000126 name: cranial nerve nucleus namespace: uberon def: "Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves." [NLX:28532] synonym: "cranial neural nucleus" EXACT [FMA:54501] synonym: "nucleus nervi cranialis" RELATED LATIN [Wikipedia:Cranial_nerve_nucleus] synonym: "nucleus of cranial nerve" EXACT [] xref: EMAPA:37066 {source="MA:th"} xref: FMA:54501 xref: NLX:28532 xref: SCTID:280160003 xref: Wikipedia:Cranial_nerve_nucleus is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: extends_fibers_into UBERON:0001785 ! cranial nerve relationship: extends_fibers_into UBERON:0001785 ! cranial nerve relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png" xsd:anyURI [Term] id: UBERON:0000127 name: facial nucleus namespace: uberon def: "The group of motor neurons residing in the pons that innervate the muscles of facial expression." [ISBN:0838580343, MP:0000909] subset: pheno_slim synonym: "facial nerve nucleus" EXACT [] synonym: "facial VII motor nucleus" RELATED [MA:0001014] synonym: "facial VII nucleus" EXACT [MA:0001014] synonym: "nucleus of facial nerve" EXACT [FMA:54572] xref: BAMS:7 xref: BAMS:7N xref: BAMS:VII xref: BM:Pons-VII xref: DHBA:12420 xref: EHDAA2:0004638 xref: EMAPA:35338 xref: EV:0100267 xref: FMA:54572 xref: MA:0001014 xref: MESH:D065828 xref: NCIT:C12898 xref: SCTID:280166009 xref: UMLS:C0228740 {source="ncithesaurus:Facial_Nerve_Nucleus"} xref: VHOG:0001412 is_a: UBERON:0000126 ! cranial nerve nucleus is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus intersection_of: UBERON:0000126 ! cranial nerve nucleus intersection_of: extends_fibers_into UBERON:0001647 ! facial nerve relationship: contributes_to_morphology_of UBERON:0000988 ! pons relationship: develops_from UBERON:0010123 ! future facial nucleus relationship: extends_fibers_into UBERON:0001647 ! facial nerve relationship: immediate_transformation_of UBERON:0010123 {evidence="definitional"} ! future facial nucleus relationship: part_of UBERON:0000988 ! pons property_value: UBPROP:0000012 "FMA has 3 subclasses - left, right and motor nucleus of facial nerve, but no defs. It's not clear how facial nucleus is distinct from facial motor nucleus." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000144 name: trochlea of humerus namespace: uberon def: "The medial portion of the articular surface of the humerus is named the trochlea, and presents a deep depression between two well-marked borders; it is convex from before backward, concave from side to side, and occupies the anterior, lower, and posterior parts of the extremity. It is directly inferior to the most prominent anterior humeral fossia, the Coronoid fossia. It articulates with the ulna." [Wikipedia:Trochlea_of_humerus] subset: human_reference_atlas synonym: "humeral trochlea" EXACT [FMA:23370] synonym: "trochlea humeri" EXACT [Wikipedia:Trochlea_of_humerus] xref: FMA:23370 xref: SCTID:282817004 xref: Wikipedia:Trochlea_of_humerus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: part_of UBERON:0004404 ! distal epiphysis of humerus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4b/Trochleahumeri.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000153 name: anterior region of body namespace: uberon is_a: UBERON:0000475 ! organism subdivision disjoint_from: UBERON:0000154 {source="lexical"} ! posterior region of body relationship: anterior_to UBERON:0000154 ! posterior region of body relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: UBERON:0000154 name: posterior region of body namespace: uberon is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: UBERON:0000158 name: membranous layer namespace: uberon synonym: "membrane" BROAD [] synonym: "membranous organ component" EXACT [FMA:82500] xref: FMA:30322 xref: FMA:82500 xref: MESH:D008566 xref: NCIT:C12749 is_a: UBERON:0004923 ! organ component layer relationship: bounding_layer_of UBERON:0000064 ! organ part property_value: UBPROP:0000001 "A thin sheet or layer of pliable tissue, serving as a covering or envelope of a part, as the lining of a cavity, as a partition or septum, or to connect two structures." xsd:string {source="ncithesaurus:Membrane"} [Term] id: UBERON:0000159 name: anal canal namespace: uberon def: "The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus." [Wikipedia:Anal_canal] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "anal canal" EXACT [] synonym: "anal canal viewed anatomically" EXACT [] synonym: "anal pad" RELATED [] synonym: "anatomical anal canal" EXACT [] synonym: "anus" RELATED [] synonym: "canalis analis" RELATED LATIN [BTO:0001978, Wikipedia:Anal_canal] synonym: "cloaca" RELATED [] synonym: "cloacal chamber" RELATED [] synonym: "mesenteron" RELATED [] synonym: "pars analis recti" RELATED [BTO:0001978] xref: BTO:0001978 xref: CALOHA:TS-2160 xref: EMAPA:18256 xref: FMA:15703 xref: galen:AnalCanal xref: MA:0000330 xref: MESH:D001003 xref: NCIT:C12375 xref: SCTID:245438008 xref: UMLS:C0227411 {source="ncithesaurus:Anal_Canal"} xref: Wikipedia:Anal_canal is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004121 ! ectoderm-derived structure relationship: channel_for UBERON:0001988 ! feces relationship: continuous_with UBERON:0001052 ! rectum relationship: continuous_with UBERON:0001245 ! anus relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! embryonic skin basal layer relationship: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001353 ! anal region property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/0/01/Gray1078.png" xsd:anyURI property_value: editor_note "requires alignment with EHDAA2 and complete developmental relationships" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000160 name: intestine namespace: uberon def: "Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine." [GOC:GO, Wikipedia:Intestine] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bowel" EXACT [] synonym: "intestinal tract" RELATED [] xref: AAO:0000246 xref: ANISEED:1235303 xref: BSA:0000093 xref: BTO:0000648 xref: CALOHA:TS-0490 xref: EFO:0000834 xref: EMAPA:32874 xref: EV:0100071 xref: FMA:7199 xref: GAID:295 xref: galen:Intestine xref: MA:0000328 xref: MA:0001524 xref: MESH:D007422 xref: MIAA:0000043 xref: NCIT:C12736 xref: SCTID:256876008 xref: TAO:0001338 xref: UMLS:C0021853 {source="ncithesaurus:Intestine"} xref: VHOG:0000056 xref: WBbt:0005772 xref: Wikipedia:Intestine xref: XAO:0000129 xref: ZFA:0001338 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system property_value: editor_note "This class is probably too inclusive" xsd:string property_value: UBPROP:0000001 "Portion of the alimentary canal bounded anteriorly by the pyloric sphincter and posteriorly by the cloacal sphincter.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000246", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "The tract of the alimentary canal. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000056", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "intestinal" xsd:string property_value: UBPROP:0000008 "In zebrafish, No stomach, small intestine, or large intestine can be distinguished. However, differences can be found in the morphology of the mucosa columnar epithelial cells and the number of goblet cells, suggesting functional differentiation. The intestine has numerous folds that become progressively shorter in a rostral-to-caudal direction. Proportionally, these folds are significantly larger than the finger-like intestinal villi of mammals and other amniotes (Wallace et al. 2005). Columnar-shaped absorptive enterocytes are the most numerous in the zebrafish intestinal epithelium. Goblet cells are the second most populous epithelial cell type." xsd:string [Term] id: UBERON:0000161 name: orifice namespace: uberon def: "Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]." [FMA:3724] synonym: "anatomical orifice" EXACT [FMA:3724] synonym: "anatomical ostium" BROAD [FMA:3724] synonym: "hilum" NARROW [] synonym: "ostium" BROAD [] xref: FMA:3724 xref: SCTID:91837002 is_a: UBERON:0004111 ! anatomical conduit property_value: UBPROP:0000012 "in FMA, this is an anatomical conduit *space*, rather than anatomical conduit" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000162 name: cloaca namespace: uberon def: "Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures." [ISBN:0073040584, Wikipedia:Cloaca] synonym: "cloacal chamber" RELATED [AAO:0000095] synonym: "vent" RELATED [XAO:0000244] xref: AAO:0000095 xref: GAID:1206 xref: MESH:D002988 xref: NCIT:C34127 xref: SCTID:362857006 xref: SCTID:370631000 xref: UMLS:C0008987 {source="ncithesaurus:Cloaca"} xref: VHOG:0001186 xref: Wikipedia:Cloaca xref: XAO:0000244 xref: ZFA:0005781 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013522 ! subdivision of tube relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001555 {source="ZFA"} ! digestive tract relationship: part_of UBERON:0004122 {source="AAO"} ! genitourinary system property_value: editor_note "adding df link to embryonic cloaca leads to a cycle in uberon-simple, as cloaca is a suberclass of embryonic cloaca" xsd:string property_value: RO:0002175 NCBITaxon:9369 {notes="most adult placentals have no trace of a cloaca. However, the tenrecs and golden moles, small placental mammals native to Africa, retain a cloaca as adults."} property_value: UBPROP:0000001 "A common passage for fecal, urinary, and reproductive discharge in most lower vertebrates as well as the terminal end of the hindgut before division into rectum, bladder, and genital primordia in mammalian embryos. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001186", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/cloaca"} property_value: UBPROP:0000001 "Anatomical structure which is the common receptacle for the alimentary canal, Wolffian ducts, oviducts, and the bladder.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000095", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "A cloaca is apparently a primitive vertebrate feature because it occurs in most primitive gnathostomes and persists in the embryos of almost all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001186", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.572", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "cloacal" xsd:string property_value: UBPROP:0000008 "Human beings only have an embryonic cloaca, which is split up into separate tracts during the development of the urinary and reproductive organs" xsd:string property_value: UBPROP:0000011 "hindgut endoderm and proctodeal ectoderm." xsd:string {source="WP"} [Term] id: UBERON:0000163 name: embryonic cloaca namespace: uberon def: "Endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]." [MP:0010115, Wikipedia:Cloaca_(embryology)] subset: pheno_slim synonym: "cloaca" RELATED SENSU [] xref: EHDAA2:0000256 xref: EHDAA:4895 xref: EMAPA:27573 xref: Wikipedia:Cloaca_(embryology) is_a: UBERON:0000162 ! cloaca relationship: has_developmental_contribution_from UBERON:0003064 ! intermediate mesoderm relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001008 {source="EHDAA2"} ! renal system relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region property_value: IAO:0000232 "this class represents the embryonic form of the cloaca, as found in both mammals and non-mammals." xsd:string [Term] id: UBERON:0000164 name: primitive urogenital sinus namespace: uberon def: "The ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females." [ISBN:0-683-40008-8, MP:0010116] subset: pheno_slim synonym: "fetal UGS" EXACT [PMID:18977204] synonym: "sinus urogenitalis" EXACT LATIN [] synonym: "UGS" EXACT [MP:0010116] synonym: "urogenital sinus" BROAD [MP:0010116] xref: EHDAA2:0004060 xref: EHDAA:5029 xref: EHDAA:5919 xref: EMAPA:17379 xref: NCIT:C34322 xref: SCTID:50961009 xref: UMLS:C0231057 {source="ncithesaurus:Urogenital_Sinus"} xref: VHOG:0000414 xref: Wikipedia:Definitive_urogenital_sinus is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: contributes_to_morphology_of UBERON:0000163 ! embryonic cloaca relationship: develops_from UBERON:0003064 ! intermediate mesoderm relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000163 {source="MP-def"} ! embryonic cloaca property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI property_value: UBPROP:0000001 "The ventral part of the cloaca after its separation from the rectum, giving rise to the lower part of the bladder in both sexes, to the prostatic portion of the male urethra, and to the urethra and vestibule in the female. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/urogenital+sinus"} property_value: UBPROP:0000003 "In mammals the lowly monotremes still have a cloaca. Higher types have done away with this structure and have a separate anal outlet for the rectum. The monotreme cloaca shows the initiation of this subdivision. The cloaca has such includes only the distal part, roughly comparable to the proctodeum. The more proximal part is divided into (1) a large dorsal passage into which the intestine opens, the coprodeum, and (2) a ventral portion, the urodeum with which the bladder connects. (...) the development of the placental mammals recapitulates in many respects the phylogenetic story. In the sexually indifferent stage of placental mammal there is a cloaca. While the indifferent stage still persists, a septum develops, and extends out to the closing membrane. This divides the cloaca into two chambers: a coprodeum continuous with the gut above, and a urodeum or urogenital sinus below.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000414", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970)p.388-89 and Figure 300", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "the term 'urogenital sinus' may refer to the primitive urogenital sinus present as a transient developmental structure in most mammals or it may refer to a condition in which an unseptated cloaca persists in animals longer than normal" xsd:string {source="MP"} [Term] id: UBERON:0000165 name: mouth namespace: uberon def: "The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, Wikipedia:Mouth] subset: efo_slim subset: major_organ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adult mouth" NARROW [] synonym: "cavital oralis" RELATED LATIN [Wikipedia:Mouth] synonym: "cavitas oris" RELATED [BTO:0001090] synonym: "cavum oris" RELATED [BTO:0001090] synonym: "mouth cavity" RELATED [BTO:0001090] synonym: "oral region" RELATED [EHDAA2:0001326] synonym: "oral vestibule" RELATED [BTO:0001090] synonym: "regio oralis" EXACT LATIN [BTO:0004698, FMA:49184, FMA:TA] synonym: "rima oris" RELATED [BTO:0001090] synonym: "stoma" RELATED [] synonym: "stomatodaeum" RELATED [VHOG:0000812] synonym: "trophic apparatus" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "vestibule of mouth" RELATED [BTO:0001090] synonym: "vestibulum oris" RELATED [BTO:0001090] xref: AAO:0010355 xref: BTO:0001090 xref: BTO:0004698 xref: CALOHA:TS-1315 xref: EFO:0000825 xref: EHDAA2:0001326 xref: EHDAA:542 xref: EMAPA:16262 xref: FBbt:00003126 xref: FMA:49184 xref: GAID:75 xref: galen:Mouth xref: http://purl.obolibrary.org/obo/uberon/images/lamprey_sucker_rosava_3238889218.jpg xref: MA:0000341 xref: MA:0002474 xref: MAT:0000038 xref: MESH:D009055 xref: MIAA:0000038 xref: SCTID:21082005 xref: TADS:0000040 xref: TAO:0000547 xref: TAO:0000590 xref: TGMA:0000131 xref: VHOG:0000280 xref: VHOG:0000812 xref: Wikipedia:Mouth xref: XAO:0003029 xref: ZFA:0000547 xref: ZFA:0000590 is_a: UBERON:0004921 {notes="the mouth contains structures such as jaw skeleton that may not strictly be considered tract parts"} ! subdivision of digestive tract intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: proximalmost_part_of UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0035804 ! future mouth relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: overlaps UBERON:0001004 {notes="exceptions in some taxa"} ! respiratory system relationship: part_of UBERON:0000033 ! head relationship: proximalmost_part_of UBERON:0001555 ! digestive tract property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/0/06/Mouth_illustration-Otis_Archives.jpg" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/661" xsd:anyURI property_value: UBPROP:0000001 "Cavity in which food is initially ingested and generally contains teeth, tongue and glands.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010355", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Molecular and developmental cell lineage data suggest that the acoel mouth opening is homologous to the mouth of protostomes and deuterostomes and that the last common ancestor of the Bilateria (the 'urbilaterian') had only this single digestive opening.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000812", ontology="VHOG", source="DOI:10.1038/nature07309 Hejnol A, Martindale MQ, Acoel development indicates the independent evolution of the bilaterian mouth and anus. Nature (2008)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "oral" xsd:string property_value: UBPROP:0000011 "some AOs place this as developing from the stomodeum but we weaken this to developmental contribution, as the mouth includes non-ectodermal derivatives" xsd:string property_value: UBPROP:0000012 "in FMA, the tongue, palate etc are part of the mouth which is itself a subdivision of the face. ZFA includes a separate class 'oral region' which is part of the mouth, but excludes tongue and lips" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000166 name: oral opening namespace: uberon def: "The orifice that connects the mouth to the exterior of the body." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract] subset: uberon_slim subset: vertebrate_core synonym: "mouth" RELATED INCONSISTENT [] synonym: "oral fissure" EXACT [FMA:59806] synonym: "oral orifice" EXACT [FMA:59806] synonym: "oral part of face" RELATED [] xref: FMA:59806 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000161 {source="FMA"} ! orifice relationship: overlaps UBERON:0001004 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! respiratory system relationship: part_of UBERON:0000165 ! mouth property_value: UBPROP:0000003 "(...) mouth development is very similar in protostomes and 'basal' deuterostomes, whereas the chordate mouth seems to develop at a new position. Recent data for echinoderms and hemichordates further suggest that this change in mouth position may result from change in the influence of a conserved ectodermal patterning system on mouth development. It has been suggested that the mouths of vertebrates and urochordates may constitute a 'new' mouth.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000280", ontology="VHOG", source="DOI:10.1016/j.semcdb.2007.06.002 Christiaen L, Jaszczyszyn Y, Kerfant M, Kanob S, Thermes V, Joly JS, Evolutionary modification of mouth position in deuterostomes. Seminars in Cell and Developmental Biology (2007)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000167 name: oral cavity namespace: uberon def: "Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present)." [https://github.com/obophenotype/uberon/wiki/The-digestive-tract, https://orcid.org/0000-0002-6601-2165, ISBN:0073040584] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bucca" RELATED [] synonym: "buccal cavity" EXACT [FMA:20292, ISBN:0073040584] synonym: "cavity of mouth" EXACT [] xref: AAO:0000053 xref: AAO:0000960 xref: BSA:0000107 xref: CALOHA:TS-1315 xref: EFO:0001975 xref: EHDAA2:0001324 xref: EHDAA:6970 xref: EMAPA:17411 xref: EMAPA:18399 xref: EV:0100057 xref: FMA:20292 xref: HAO:0000669 xref: NCIT:C12421 xref: SCTID:181220002 xref: TAO:0001027 xref: TGMA:0000102 xref: UMLS:C0226896 {source="ncithesaurus:Oral_Cavity"} xref: VHOG:0000188 xref: WBbt:0005255 xref: XAO:0000126 xref: ZFA:0001027 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000165 ! mouth relationship: contributes_to_morphology_of UBERON:0000165 ! mouth relationship: luminal_space_of UBERON:0000165 ! mouth relationship: part_of UBERON:0000165 ! mouth property_value: UBPROP:0000001 "Anatomical cavity bounded anteriorly by the mouth and posteriorly by the derivatives of the branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000960", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "The cavity of the mouth, bounded by the jaw bones and associated structures (muscles and mucosa). [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000188", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/oral+cavity"} property_value: UBPROP:0000003 "Echinoderms, hemichordates, and chordates are called deuterostomes because the mouth arises not from the blastopore but from a second invagination at the anterior end of the larva that pushes in to connect with the archenteron.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000188", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.32", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000168 name: proximal-distal subdivision of colon namespace: uberon def: "A section dividing a colon along a proximal-distal axis." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "segment of colon" RELATED [FMA:222905] xref: FMA:222905 is_a: UBERON:0004921 {order="4", source="cjm"} ! subdivision of digestive tract intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: subdivision_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon relationship: subdivision_of UBERON:0001155 ! colon [Term] id: UBERON:0000170 name: pair of lungs namespace: uberon def: "The pair of anatomical structures comprised of a left lung and right lung." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim synonym: "lungs" EXACT [] synonym: "lungs pair" EXACT [] synonym: "pulmones" EXACT LATIN [FMA:68877, FMA:TA] synonym: "set of lungs" EXACT [] xref: FMA:68877 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034925 ! anatomical collection intersection_of: UBERON:0034925 ! anatomical collection intersection_of: has_member UBERON:0002167 ! right lung intersection_of: has_member UBERON:0002168 ! left lung relationship: has_member UBERON:0002167 ! right lung relationship: has_member UBERON:0002167 {cardinality="1"} ! right lung relationship: has_member UBERON:0002168 ! left lung relationship: has_member UBERON:0002168 {cardinality="1"} ! left lung relationship: located_in UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0001558 {source="FMA-abduced"} ! lower respiratory tract property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000171 name: respiration organ namespace: uberon def: "Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." [GO:0007585] subset: functional_classification subset: organ_slim synonym: "apparatus respiratorius organ" EXACT [OBOL:automatic] synonym: "breathing organ" EXACT [] synonym: "gas exchange organ" RELATED [] synonym: "organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "organ of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory organ" EXACT [] synonym: "respiratory system organ" EXACT [OBOL:automatic] xref: EMAPA:17607 xref: SCTID:272626006 xref: SPD:0000428 xref: TGMA:0001247 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0000174 name: excreta namespace: uberon alt_id: UBERON:0000324 alt_id: UBERON:0007550 def: "A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity." [GO:0007588, http://orcid.org/0000-0002-6601-2165] synonym: "excreted substance" EXACT [] synonym: "excretion" RELATED [BTO:0000491] synonym: "portion of excreted substance" EXACT [FMA:9674] synonym: "waste substance" EXACT [AEO:0000184] xref: AEO:0000184 xref: BTO:0000491 xref: EHDAA2_RETIRED:0003184 xref: ENVO:02000022 xref: FMA:9674 xref: galen:Excretion is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: output_of GO:0007588 ! excretion relationship: output_of GO:0007588 ! excretion [Term] id: UBERON:0000178 name: blood namespace: uberon def: "A fluid that is composed of blood plasma and erythrocytes." [FMA:9670, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/9, Wikipedia:Blood] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "portion of blood" EXACT [] synonym: "vertebrate blood" EXACT [] synonym: "whole blood" RELATED [BTO:0000089] xref: AAO:0000046 xref: BTO:0000089 xref: CALOHA:TS-0079 xref: EFO:0000296 xref: EHDAA2:0000176 xref: EHDAA:418 xref: EMAPA:16332 xref: ENVO:02000027 xref: EV:0100047 xref: FMA:9670 xref: GAID:965 xref: galen:Blood xref: MA:0000059 xref: MESH:D001769 xref: MIAA:0000315 xref: NCIT:C12434 xref: TAO:0000007 xref: UMLS:C0005767 {source="ncithesaurus:Blood"} xref: VHOG:0000224 xref: Wikipedia:Blood xref: XAO:0000124 xref: ZFA:0000007 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000179 ! haemolymphatic fluid relationship: develops_from UBERON:0006596 ! presumptive blood relationship: has_part CL:0000232 {source="CL:tm"} ! erythrocyte relationship: has_part UBERON:0001969 ! blood plasma relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/tmeehan relationship: immediate_transformation_of UBERON:0006596 {source="Bgee:AN"} ! presumptive blood relationship: located_in UBERON:0002049 {source="https://github.com/obophenotype/uberon/issues/1330"} ! vasculature relationship: part_of UBERON:0002390 ! hematopoietic system property_value: IAO:0000232 "This class excludes blood analogues, such as the insect analog of blood. See UBERON:0000179 haemolymphatic fluid." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A complex mixture of cells suspended in a liquid matrix that delivers nutrients to cells and removes wastes. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000007", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Highly specialized circulating tissue consisting of several types of cells suspended in a fluid medium known as plasma.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000046", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000046", ontology="AAO"} property_value: UBPROP:0000003 "Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrates phyla. (...) There is now good reason to believe that, in vertebrates and invertebrates alike, blood cell lineages diverge from a common type of progenitor cell, the hemocytoblast.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000224", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V, Blood cells and blood cell development in the animal kingdom. Annual review of cell and developmental biology (2006) ", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000179 name: haemolymphatic fluid namespace: uberon def: "Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs." [http://orcid.org/0000-0002-6601-2165] synonym: "blood or blood analog" RELATED [] synonym: "circulating fluid" RELATED [] xref: CARO:0000081 is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: part_of UBERON:0002193 ! hemolymphoid system relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0002193 ! hemolymphoid system creation_date: 2009-04-08T04:38:19Z [Term] id: UBERON:0000199 name: neck of radius namespace: uberon def: "The narrow part of the shaft of the radius just below the head." [http://www.medilexicon.com/medicaldictionary.php?t=58913] subset: pheno_slim synonym: "collum radii" EXACT [_rib] synonym: "radial neck" EXACT [FMA:23479] xref: FMA:23479 xref: galen:NeckOfRadius xref: SCTID:181942005 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0018664 ! neck of bone element intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0001423 ! radius bone relationship: part_of UBERON:0004413 {source="FMA"} ! proximal epiphysis of radius [Term] id: UBERON:0000200 name: gyrus namespace: uberon def: "A ridge on the cerebral cortex. It is generally surrounded by one or more sulci ." [https://github.com/obophenotype/uberon/issues/573, Wikipedia:Gyrus] subset: pheno_slim synonym: "cerebral gyrus" EXACT [BTO:0002495] synonym: "folia" RELATED PLURAL [] synonym: "folium" RELATED [PHENOSCAPE:wd] synonym: "folium of brain" RELATED [] synonym: "gyri" RELATED PLURAL [BTO:0002495] synonym: "gyri of cerebrum" RELATED PLURAL [BTO:0002495] synonym: "gyrus of cerebral hemisphere" RELATED [FMA:83874] synonym: "gyrus of cerebrum" RELATED [BTO:0002495] synonym: "gyrus of neuraxis" EXACT [FMA:83874] synonym: "neuraxis gyrus" EXACT [FMA:83874] xref: BTO:0002495 xref: FMA:83874 xref: NCIT:C32290 xref: neuronames:1211 xref: SCTID:279165009 xref: UMLS:C0458308 {source="ncithesaurus:Cerebral_Gyrus"} xref: Wikipedia:Gyrus is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034768 ! morphological feature relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/RDruzinsky relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0000956 ! cerebral cortex relationship: surrounded_by UBERON:0013118 ! sulcus of brain property_value: RO:0002174 NCBITaxon:10088 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/573" xsd:anyURI property_value: UBPROP:0000202 FMA:72015 [Term] id: UBERON:0000203 name: pallium namespace: uberon alt_id: UBERON:0007333 def: "Dorsal part (roof region) of the telencephalon[GO]." [GO:0021543, https://github.com/obophenotype/uberon/issues/287, ISBN:0471888893, Wikipedia:Pallium_(neuroanatomy)] subset: developmental_classification subset: efo_slim synonym: "area dorsalis telencephali" EXACT [ZFA:0000505] synonym: "dorsal part of telencephalon" EXACT [ISBN:0471888893] synonym: "dorsal telencephalic area" EXACT [ZFA:0000505] synonym: "dorsal telencephalon" EXACT [ZFA:0000505] xref: BTO:0003399 xref: DMBA:15903 xref: EFO:0003534 xref: neuronames:3240 xref: SCTID:369224000 xref: TAO:0000505 xref: TAO:0007007 xref: Wikipedia:Avian_pallium xref: Wikipedia:Pallium_(neuroanatomy) xref: ZFA:0000505 is_a: UBERON:0002616 ! regional part of brain relationship: dc-contributor https://orcid.org/0000-0002-6601-2165 relationship: part_of UBERON:0001893 ! telencephalon property_value: RO:0002175 NCBITaxon:7762 {source="PMID:8932866"} property_value: seeAlso "https://sourceforge.net/p/obo/zebrafish-anatomy-zfa-term-requests/87" xsd:anyURI property_value: UBPROP:0000003 "In the anatomy of animals, an avian pallium is the dorsal telencephalon of a bird's brain. Pallium of avian species tend to be relatively large, comprising ~75% of the telencephalic volume." xsd:string {source="Wikipedia:Avian_pallium", taxon="NCBITaxon:8782"} property_value: UBPROP:0000008 "In humans the cerebrum has three parts: the archipallium, the paleopallium and the neopallium. The developing telencephalon or forebrain is divided into pallium and subpallium. In amphibians, the cerebrum includes archipallium, paleopallium and some of the basal nuclei. Reptiles first developed a neopallium, which continued to develop in the brains of more recent species to become the neocortex of humans and Old World monkeys. In fish, the archipallium is the largest part of the cerebrum. Some researchers suggest the early archipallium gave rise to the human hippocampus" xsd:string {source="WP"} creation_date: 2009-04-18T12:03:09Z [Term] id: UBERON:0000209 name: tetrapod frontal bone namespace: uberon def: "The bone forming the forehead and roof of the eye orbit." [ISBN:0-683-40008-8, MP:0000107, PMID:7914451, Wikipedia:Frontal_bone] subset: human_reference_atlas subset: pheno_slim synonym: "frontal" NARROW [AAO:0000206] synonym: "frontal bone" NARROW SENSU [FMA:52734, MA:0001466] synonym: "os frontal" NARROW SENSU [Wikipedia:Frontal_bone] synonym: "os frontale" RELATED LATIN [Wikipedia:Frontal_bone] xref: AAO:0000206 xref: EMAPA:19016 xref: FMA:52734 xref: GAID:226 xref: MA:0001466 xref: MESH:D005624 xref: NCIT:C32635 xref: SCTID:181793006 xref: UMLS:C0016732 {source="ncithesaurus:Frontal_Bone"} xref: VHOG:0001324 xref: VSAO:0000208 xref: Wikipedia:Frontal_bone is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0008907 ! dermal bone is_a: UBERON:0010428 {source="FMA"} ! flat bone is_a: UBERON:0011164 ! neurocranium bone relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid bone relationship: overlaps UBERON:0001697 ! orbit of skull relationship: part_of UBERON:0003113 {source="cjm"} ! dermatocranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray136.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/5b/Frontal_bone.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "fused in humans, paired in other animals" xsd:string property_value: UBPROP:0000011 "In the mouse the parietal originates from cephalic paraxial mesoderm (Jiang 2000; Morriss-Kay 2001), whereas in the chicken it is traced back to either mesodermal (Noden 1978) or neural crest (Couly 1992, 1993)." xsd:string [Term] id: UBERON:0000211 name: ligament namespace: uberon def: "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000073] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "ligament organ" EXACT [FMA:21496] xref: CALOHA:TS-2145 xref: EFO:0001966 xref: EMAPA:35493 xref: FMA:21496 xref: FMA:30319 xref: galen:Ligament xref: MA:0000113 xref: MESH:D008022 xref: NCIT:C13046 xref: SCTID:182358004 xref: TAO:0001682 xref: UMLS:C0023685 {source="ncithesaurus:Ligament"} xref: VHOG:0001272 xref: Wikipedia:Ligament xref: XAO:0004031 xref: ZFA:0001675 is_a: UBERON:0000062 ! organ relationship: has_part UBERON:0002384 ! connective tissue relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg" xsd:anyURI property_value: UBPROP:0000001 "Nonparenchymatous organ that primarily consists of dense connective tissue aggregated into fasciculi by connective tissue. Examples: sutural ligament, radiate sternocostal ligament, ligament of liver, ovarian ligament[FMA][FMA:21496]." xsd:string {source="FMA:21496"} property_value: UBPROP:0000001 "Portion of connective tissue that connects bone or cartilage.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001682", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000003 "Compared with their Ediacarian predecessor, Cambrian animals in general were characterized by their much stouter bodies. The stoutness of the body is likely due to the formation of ligaments and tendons, which in turn requires the crosslinking of collagen triple helices.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001272", ontology="VHOG", source="PMID:8710894 Ohno S, The notion of the Cambrian pananimalia genome. PNAS (1996)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "this groups both skeletal and non-skeletal ligaments. What is called a 'ligament' in many AOs is actually a skeletal ligament" xsd:string [Term] id: UBERON:0000218 name: vertebral arch of axis namespace: uberon def: "A neural arch that is part of a vertebral bone 2." [OBOL:automatic] synonym: "vertebral foramen of cervical vertebra 2" EXACT [] xref: FMA:24053 is_a: UBERON:0003861 ! neural arch intersection_of: UBERON:0003861 ! neural arch intersection_of: part_of UBERON:0001093 ! vertebral bone 2 relationship: part_of UBERON:0001093 ! vertebral bone 2 [Term] id: UBERON:0000219 name: vertebral foramen of atlas namespace: uberon synonym: "vertebral foramen of cervical vertebra 1" EXACT [] xref: FMA:24293 xref: SCTID:281228008 xref: Wikipedia:Atlas_(anatomy)#Vertebral_foramen is_a: UBERON:0001131 ! vertebral foramen is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0001092 ! vertebral bone 1 relationship: part_of UBERON:0001092 ! vertebral bone 1 [Term] id: UBERON:0000220 name: atlanto-occipital joint namespace: uberon def: "The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital." [Wikipedia:Atlanto-occipital_joint] synonym: "articulatio atlanto-occipitalis" EXACT [FMA:24939] synonym: "articulatio atlantooccipitalis" RELATED LATIN [Wikipedia:Atlanto-occipital_joint] synonym: "atlanto occipital joint" EXACT [] synonym: "atlantooccipital joint" EXACT [] synonym: "craniovertebral joint" EXACT [FMA:24939] synonym: "occipito atlantal joint" EXACT [] synonym: "occipito-atlantal joint" EXACT [] xref: FMA:24939 xref: MESH:D001269 xref: NCIT:C32158 xref: ncithesaurus:Atlanto-occipital_Joint-Atlanto xref: SCTID:361831006 xref: UMLS:C0004169 {source="ncithesaurus:Atlanto-occipital_Joint"} xref: Wikipedia:Atlanto-occipital_joint is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002217 ! synovial joint is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0002217 ! synovial joint intersection_of: connects UBERON:0001092 ! vertebral bone 1 intersection_of: connects UBERON:0001676 ! occipital bone relationship: connects UBERON:0001092 ! vertebral bone 1 relationship: connects UBERON:0001676 ! occipital bone relationship: in_lateral_side_of UBERON:0006072 {source="FMA-abduced-lr"} ! cervical region of vertebral column relationship: part_of UBERON:0006072 ! cervical region of vertebral column property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png" xsd:anyURI [Term] id: UBERON:0000304 name: tendon sheath namespace: uberon def: "A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath." [Wikipedia:Tendon_sheath] synonym: "synovial tendon sheath" EXACT [FMA:45087] synonym: "vagina tendinis" RELATED LATIN [Wikipedia:Tendon_sheath] xref: BTO:0000051 xref: FMA:45087 xref: FMA:76715 xref: NCIT:C96299 xref: SCTID:361885006 xref: UMLS:C0224856 {source="ncithesaurus:Tendon_Sheath"} xref: Wikipedia:Tendon_sheath is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: bounding_layer_of UBERON:0000043 ! tendon relationship: bounding_layer_of UBERON:0000043 ! tendon relationship: has_part UBERON:0011233 ! synovial membrane of synovial tendon sheath relationship: has_part UBERON:0011234 ! fibrous membrane of synovial tendon sheath relationship: part_of UBERON:0000043 ! tendon property_value: editor_note "TODO - add layer relations. 'tendon sheath' GAT in FMA." xsd:string [Term] id: UBERON:0000307 name: blastula namespace: uberon alt_id: UBERON:0007011 def: "Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence." [Wikipedia:Blastula] subset: inconsistent_with_fma synonym: "blastosphere" RELATED [Wikipedia:Blastula] synonym: "blastula embryo" EXACT [BILA:0000059] xref: BILA:0000059 xref: BTO:0000128 xref: GAID:1294 xref: MESH:D036703 xref: OGEM:000006 xref: Wikipedia:Blastula is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_and_ends_during UBERON:0000108 ! blastula stage relationship: develops_from UBERON:0007010 ! cleaving embryo relationship: existence_starts_and_ends_during UBERON:0000108 ! blastula stage property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c6/Blastulation.png" xsd:anyURI property_value: editor_note "TODO - check relationship with epiblast. Note in FMA this is not a subclass of embryo, but in uberon embryo is the whole organism from zygote onwards and thus includes the blastula" xsd:string [Term] id: UBERON:0000309 name: body wall namespace: uberon def: "The external portion of an animal body derived from ectoderm and mesoderm layers that encloses the body cavity." [MP:0003385] subset: pheno_slim synonym: "trunk wall" NARROW [FMA:10427] synonym: "wall fo trunk" EXACT [FMA:10427] synonym: "wall of trunk" NARROW [FMA:10427] xref: BTO:0000139 xref: EMAPA:32761 xref: FMA:10427 xref: galen:BodyWall xref: SCTID:281483004 is_a: UBERON:0000475 ! organism subdivision property_value: UBPROP:0000008 "defined generically to encompass both vertebrates and invertebrates" xsd:string property_value: UBPROP:0000012 "the BTO class refers to earthworms." xsd:string {external_ontology="BTO"} [Term] id: UBERON:0000313 name: portion of cartilage tissue in tibia namespace: uberon def: "Cartilage pertaining to the tibia." [Dorlands_Medical_Dictionary:MerckSource] synonym: "cartilage of tibia" RELATED [FMA:33923] synonym: "tibial cartilage" EXACT [] xref: BTO:0000207 xref: FMA:33923 is_a: UBERON:0004270 ! lower leg connective tissue is_a: UBERON:0007391 ! pelvic appendage cartilage tissue intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0000979 ! tibia relationship: part_of UBERON:0000979 ! tibia property_value: IAO:0000232 "This class represents a portion of cartilage tissue located in the tibia, *not* the cartilaginous condensation of an emrbyonic tibia" xsd:string [Term] id: UBERON:0000317 name: colonic mucosa namespace: uberon alt_id: UBERON:0003347 alt_id: UBERON:0004981 def: "Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: human_reference_atlas synonym: "colon mucosa" EXACT [FMA:14984] synonym: "colon mucous membrane" EXACT [OBOL:automatic] synonym: "colonic mucosa" EXACT [] synonym: "colonic mucous membrane" EXACT [FMA:14984] synonym: "large bowel mucosa" EXACT [OBOL:automatic] synonym: "mucosa of colon" EXACT [FMA:14984] synonym: "mucosa of large bowel" EXACT [OBOL:automatic] xref: BTO:0000271 xref: CALOHA:TS-0164 xref: EFO:0003038 xref: EMAPA:27375 xref: FMA:14984 xref: FMA:85388 xref: MA:0003194 xref: SCTID:362157008 is_a: UBERON:0001207 ! mucosa of large intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000320 name: duodenal mucosa namespace: uberon alt_id: UBERON:0003348 def: "A mucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "doudenal mucosa" EXACT [FMA:14942] synonym: "duodenal mucous membrane" EXACT [FMA:14942] synonym: "duodenum mucosa" RELATED [BTO:0000367] synonym: "mucosa of duodenum" EXACT [OBOL:automatic] synonym: "mucous membrane of duodenum" EXACT [OBOL:automatic] xref: BTO:0000367 xref: CALOHA:TS-0213 xref: EMAPA:27235 xref: FMA:14942 xref: MA:0003207 xref: SCTID:362146003 is_a: UBERON:0001204 ! mucosa of small intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000323 name: late embryo namespace: uberon def: "An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching." [https://orcid.org/0000-0003-3308-6245] subset: efo_slim subset: pheno_slim synonym: "embryo late growth stage" RELATED [BTO:0000449] synonym: "embryo late stage" RELATED [BTO:0000449] synonym: "fetus" NARROW [BTO:0000449] xref: BTO:0000449 xref: CALOHA:TS-0360 xref: EFO:0001323 xref: FBbt:00005333 xref: FMA:63919 xref: GAID:552 xref: MESH:D005333 xref: NCIT:C13235 xref: SCTID:83418008 xref: UMLS:C0015965 {source="ncithesaurus:Fetus"} is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000922 ! embryo intersection_of: existence_starts_and_ends_during UBERON:0007220 ! late embryonic stage relationship: existence_starts_and_ends_during UBERON:0007220 ! late embryonic stage property_value: editor_note "TODO - check fetus/embryo. WP: An embryo is a multicellular diploid eukaryote in its earliest stage of development, from the time of first cell division until birth, hatching, or germination. In humans, it is called an embryo until about eight weeks after fertilization (i.e. ten weeks LMP), and from then it is instead called a fetus." xsd:string property_value: UBPROP:0000001 "Fetal structure, which is a developmental form of a vertebrate animal at any given time point from 8 weeks of gestation to birth (or hatching). Examples: There is only one fetus[FMA:63919]." xsd:string {source="FMA:63919"} [Term] id: UBERON:0000325 name: gastric gland namespace: uberon def: "The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin." [MGI:anna] subset: organ_slim subset: pheno_slim xref: BTO:0000503 xref: EMAPA:27181 xref: FMA:14919 is_a: UBERON:0002365 {source="cjm"} ! exocrine gland is_a: UBERON:0003294 ! gland of foregut relationship: part_of UBERON:0006924 {source="ISBN:0073040584"} ! stomach glandular epithelium [Term] id: UBERON:0000326 name: pancreatic juice namespace: uberon def: "Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach." [GO:0030157] synonym: "pancreatic fluid" RELATED [] synonym: "pancreatic secretion" RELATED [] synonym: "succus pancreaticus" RELATED [BTO:0000504] xref: BTO:0000504 xref: CALOHA:TS-2235 xref: FMA:62973 xref: GAID:1166 xref: MESH:D010189 is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0001264 ! pancreas relationship: produced_by UBERON:0001264 ! pancreas [Term] id: UBERON:0000328 name: gut wall namespace: uberon def: "The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity)." [http://orcid.org/0000-0002-6601-2165] synonym: "digestive tract wall" EXACT [] synonym: "wall of alimentary tract" RELATED [] synonym: "wall of digestive tract" EXACT [] synonym: "wall of gut" EXACT [FMA:45653] xref: BTO:0000547 xref: FMA:45653 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000060 ! anatomical wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract property_value: IAO:0000232 "We model the digestive tract as consisting of two parts: the wall and the lumen." xsd:string [Term] id: UBERON:0000332 name: yellow bone marrow namespace: uberon def: "Bone marrow in which the fat cells predominate in the meshes of the reticular network." [http://medical-dictionary.thefreedictionary.com/Yellow+Marrow] synonym: "fat marrow" RELATED [BTO:0000635] synonym: "medulla ossium flava" EXACT LATIN [BTO:0000635] synonym: "yellow marrow" EXACT [BTO:0000635] xref: BTO:0000635 xref: FMA:74596 xref: SCTID:328639002 xref: SCTID:5023006 is_a: UBERON:0002371 ! bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: composed_primarily_of CL:0000136 ! fat cell relationship: composed_primarily_of CL:0000136 ! fat cell relationship: part_of UBERON:0007195 ! stroma of bone marrow [Term] id: UBERON:0000333 name: intestinal gland namespace: uberon def: "A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]." [https://orcid.org/0000-0002-6601-2165] subset: organ_slim synonym: "bowel mucosa gland" EXACT [OBOL:automatic] synonym: "bowel mucosa of organ gland" EXACT [OBOL:automatic] synonym: "bowel mucous membrane gland" EXACT [OBOL:automatic] synonym: "bowel organ mucosa gland" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa" EXACT [OBOL:automatic] synonym: "gland of bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of bowel mucous membrane" EXACT [OBOL:automatic] synonym: "gland of bowel organ mucosa" EXACT [OBOL:automatic] synonym: "gland of intestinal mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa" EXACT [OBOL:automatic] synonym: "gland of intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "gland of intestine mucous membrane" EXACT [OBOL:automatic] synonym: "gland of intestine organ mucosa" EXACT [OBOL:automatic] synonym: "gland of mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of intestine" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of bowel" EXACT [OBOL:automatic] synonym: "gland of mucosa of organ of intestine" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of bowel" EXACT [OBOL:automatic] synonym: "gland of mucous membrane of intestine" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of bowel" EXACT [OBOL:automatic] synonym: "gland of organ mucosa of intestine" EXACT [OBOL:automatic] synonym: "glandula intestinalis" EXACT [FMA:15052] synonym: "glandulae intestinales" RELATED [] synonym: "intestinal mucosa gland" EXACT [OBOL:automatic] synonym: "intestine mucosa gland" EXACT [OBOL:automatic] synonym: "intestine mucosa of organ gland" EXACT [OBOL:automatic] synonym: "intestine mucous membrane gland" EXACT [OBOL:automatic] synonym: "intestine organ mucosa gland" EXACT [OBOL:automatic] synonym: "mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of intestine gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of bowel gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of intestine gland" EXACT [OBOL:automatic] synonym: "mucous membrane of bowel gland" EXACT [OBOL:automatic] synonym: "mucous membrane of intestine gland" EXACT [OBOL:automatic] synonym: "organ mucosa of bowel gland" EXACT [OBOL:automatic] synonym: "organ mucosa of intestine gland" EXACT [OBOL:automatic] xref: BTO:0000640 xref: FMA:15052 xref: SCTID:266297002 is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001242 ! intestinal mucosa relationship: part_of UBERON:0001242 ! intestinal mucosa property_value: UBPROP:0000012 "Note that some sources treat 'intestinal gland' as synonymous with crypts" xsd:string [Term] id: UBERON:0000344 name: mucosa namespace: uberon def: "A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]." [Wikipedia:Mucous_membrane] subset: pheno_slim synonym: "mucosa of organ" EXACT [FMA:85355] synonym: "mucosa of organ part" EXACT [FMA:85358] synonym: "mucosal region" EXACT [FMA:85358] synonym: "mucous membrane" EXACT [FMA:85355] synonym: "organ mucosa" EXACT [FMA:85355] synonym: "region of mucosa" RELATED [FMA:85358] synonym: "tunica mucosa" RELATED LATIN [BTO:0000886, Wikipedia:Mucous_membrane] xref: AEO:0000199 xref: BTO:0000886 xref: CALOHA:TS-2031 xref: EHDAA2_RETIRED:0003234 xref: EV:0100382 xref: FMA:85355 xref: FMA:85358 xref: GAID:297 xref: galen:Mucosa xref: MESH:D009092 xref: NCIT:C13166 xref: SCTID:361693009 xref: UMLS:C0026724 {source="ncithesaurus:Mucosa"} xref: Wikipedia:Mucous_membrane is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 ! organ component layer relationship: has_part UBERON:0000483 ! epithelium relationship: has_part UBERON:0002384 ! connective tissue relationship: only_in_taxon NCBITaxon:7711 ! Chordata property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4e/Ens.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/en/thumb/4/4e/Ens.png/200px-Ens.png" xsd:anyURI property_value: RO:0002171 UBERON:0000009 property_value: UBPROP:0000007 "mucosal" xsd:string property_value: UBPROP:0000012 "FMA has mucosa vs region of mucosa; these are subtypes of Mucosa: Mucosa of gallbladder, tongue, .... The following are subtypes of Region of mucosa: Mucosa of zone of stomach, trachea, bronchus, dorsum of tongue.... Depends on whether the covered area is an organ or organ component. Uberon does not regard organ vs organ component as crucial distinction and thus collapses these into a single class deliberately" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000351 name: nuchal ligament namespace: uberon def: "A fibrous membrane, which, in the neck, represents the supraspinal ligaments of the upper vertebrae." [Wikipedia:Nuchal_ligament] synonym: "ligament of neck" EXACT [FMA:13427] synonym: "ligamentum nuchae" EXACT LATIN [FMA:13427] synonym: "paddywhack" NARROW [NCBITaxon:9895, Wikipedia:Paddywhack] synonym: "paxwax" RELATED [] xref: BTO:0000952 xref: EMAPA:19207 xref: FMA:13427 xref: SCTID:166962007 xref: Wikipedia:Nuchal_ligament is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0008846 ! skeletal ligament relationship: attaches_to UBERON:0001676 ! occipital bone relationship: attaches_to UBERON:0002413 {notes="C7 in humans"} ! cervical vertebra relationship: part_of UBERON:0012477 {source="BTO"} ! dorsal part of neck property_value: RO:0002161 NCBITaxon:9596 property_value: RO:0002175 NCBITaxon:9606 property_value: RO:0002175 NCBITaxon:9608 property_value: RO:0002175 NCBITaxon:9788 property_value: RO:0002175 NCBITaxon:9895 property_value: UBPROP:0000008 "In humans it is a tendon-like structure that has developed independently in humans and other animals well adapted for running. In some four legged animals, particularly ungulates, the nuchal ligament serves to sustain the weight of the head" xsd:string property_value: UBPROP:0000009 "As it is required for running, not all animals have a nuchal ligament" xsd:string [Term] id: UBERON:0000353 name: parenchyma namespace: uberon def: "Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues." [Wikipedia:Parenchyma] xref: EHDAA:3015 xref: EHDAA:3905 xref: EHDAA:3999 xref: EHDAA:4005 xref: EHDAA:6899 xref: EHDAA:6903 xref: EHDAA:6994 xref: EHDAA:8086 xref: EHDAA:9182 xref: EHDAA:9190 xref: EHDAA:9196 xref: EHDAA:9202 xref: FMA:45732 xref: NCIT:C74601 xref: UMLS:C0933845 {source="ncithesaurus:Parenchyma"} xref: Wikipedia:Parenchyma is_a: UBERON:0000064 ! organ part disjoint_from: UBERON:0003891 ! stroma relationship: capable_of GO:0032501 ! multicellular organismal process relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000007 "parenchymal" xsd:string property_value: UBPROP:0000011 "Early in development the mammalian embryo has three distinct layers: ectoderm (external layer), endoderm (internal layer) and in between those two layers the middle layer or mesoderm. The parenchyma of most organs is of ectodermal (brain, skin) or endodermal origin (lungs, gastrointestinal tract, liver, pancreas). The parenchyma of a few organs (spleen, kidneys, heart) is of mesodermal origin. The stroma of all organs is of mesodermal origin" xsd:string {source="WP"} property_value: UBPROP:0000012 "the FMA definition is more restrictive, and limits this to solid organs. This would seem to cause problems for the lung parenchyma, except FMA classifies Lung as solid rather than cavitated" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000355 name: pharyngeal mucosa namespace: uberon alt_id: UBERON:0003344 def: "A mucosa that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of pharynx" EXACT [FMA:55031, OBOL:automatic] synonym: "mucous membrane of the pharynx" RELATED [BTO:0001047] synonym: "organ mucosa of pharynx" EXACT [OBOL:automatic] synonym: "pharynx mucosa" EXACT [OBOL:automatic] synonym: "pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa pharyngea" EXACT LATIN [FMA:55031, FMA:TA] synonym: "tunica mucosa pharyngis" EXACT [] xref: BTO:0001047 xref: EMAPA:26957 xref: FMA:55031 xref: MA:0003143 xref: SCTID:362121003 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004785 ! respiratory system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 ! chordate pharynx [Term] id: UBERON:0000358 name: blastocyst namespace: uberon def: "The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]." [GO:0001824, Wikipedia:Blastocyst] subset: efo_slim synonym: "blastocystis" RELATED LATIN [Wikipedia:Blastocyst] synonym: "blastula" RELATED [FMA:83041] xref: BTO:0001099 xref: CALOHA:TS-0076 xref: EFO:0000295 xref: EMAPA:36035 xref: EV:0100394 xref: FMA:83041 xref: GAID:1153 xref: MESH:D001755 xref: NCIT:C13739 xref: SCTID:308837009 xref: UMLS:C1281743 {source="ncithesaurus:Blastocyst"} xref: Wikipedia:Blastocyst is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000085 ! morula relationship: existence_starts_and_ends_during UBERON:0000108 ! blastula stage relationship: has_part UBERON:0000087 ! inner cell mass relationship: has_part UBERON:0000088 ! trophoblast relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: part_of UBERON:0000307 ! blastula property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/72/Blastocyst_English.svg" xsd:anyURI property_value: editor_note "Gilbert fig11.32 has blastocyst has giving rise to ICM and trophoblast (which in this source is a synonym for trophectoderm)" xsd:string [Term] id: UBERON:0000361 name: red bone marrow namespace: uberon def: "The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream." [http://medical-dictionary.thefreedictionary.com/red+marrow] synonym: "medulla ossium rubra" EXACT LATIN [BTO:0001160] synonym: "parenchyma of none marrow marrow" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "parenchymal red marrow" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "red marrow" EXACT [BTO:0001160] xref: BTO:0001160 xref: FMA:74595 xref: SCTID:328538003 xref: SCTID:75330005 is_a: UBERON:0002371 ! bone marrow intersection_of: UBERON:0002371 ! bone marrow intersection_of: composed_primarily_of CL:0000988 ! hematopoietic cell relationship: composed_primarily_of CL:0000988 ! hematopoietic cell relationship: part_of UBERON:0012429 ! hematopoietic tissue [Term] id: UBERON:0000375 name: mandibular nerve namespace: uberon def: "The motor and sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the auricle, the external acoustic meatus, tympanic membrane, temporal region, the cheek, the skin overlying the mandible, the anterior portion of the tongue, the floor of the mouth, lower teeth and gingiva and transmits motor information from the muscles of mastication, the mylohyoid muscle and digastric muscle and the muscles tensor tympani and tensor veli palatini." [MP:0009800, Wikipedia:Mandibular_nerve] subset: human_reference_atlas subset: pheno_slim synonym: "inferior maxillary nerve" EXACT [FMA:52996] synonym: "mandibular division [V3]" EXACT [FMA:52996] synonym: "mandibular division [Vc]" EXACT [FMA:52996] synonym: "mandibular division of fifth cranial nerve" EXACT [FMA:52996] synonym: "mandibular division of trigeminal nerve [Vc; V3]" EXACT [FMA:52996] synonym: "mandibular nerve [V3]" EXACT [FMA:52996] synonym: "mandibular nerve [Vc]" EXACT [FMA:52996] synonym: "n. mandibularis" RELATED LATIN [Wikipedia:Mandibular_nerve] synonym: "nervus mandibularis" RELATED [BTO:0001375] synonym: "nervus mandibularis [v3]" EXACT LATIN [FMA:52996, FMA:TA] synonym: "nervus mandibularis [Vc; V3]" EXACT [FMA:52996] synonym: "nervus mandibularis [vc]" EXACT LATIN [FMA:52996, FMA:TA] synonym: "ramus mandibularis (ramus V3)" EXACT [AAO:0010688] synonym: "third division of fifth cranial nerve" EXACT [FMA:52996] synonym: "third division of trigeminal nerve" EXACT [FMA:52996] synonym: "trigeminal nerve mandibular division" RELATED [EMAPA:17798] synonym: "trigeminal V nerve mandibular division" EXACT [MA:0001101] xref: AAO:0010688 xref: AAO:0010703 xref: BTO:0001375 xref: EHDAA2:0002086 xref: EMAPA:17798 xref: FMA:52996 xref: GAID:834 xref: MA:0001101 xref: MESH:D008340 xref: NCIT:C32779 xref: SCTID:280212008 xref: UMLS:C0024695 {source="ncithesaurus:Inferior_Maxillary_Nerve"} xref: VHOG:0001345 xref: Wikipedia:Mandibular_nerve is_a: UBERON:0011779 ! nerve of head region relationship: branching_part_of UBERON:0001645 ! trigeminal nerve relationship: part_of UBERON:0001645 ! trigeminal nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray781.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000376 name: hindlimb stylopod namespace: uberon def: "The part of the hindlimb between pelvis and the knee, corresponding to the femur." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim synonym: "femur" RELATED LATIN [Wikipedia:Thigh] synonym: "hind limb stylopod" EXACT [OBOL:automatic] synonym: "hind limb stylopodium" EXACT [VHOG:0000349] synonym: "hind propodium" EXACT [AAO:0000887] synonym: "hindlimb propodium" EXACT [AAO:0000887] synonym: "hindlimb stylopod" EXACT [OBOL:automatic] synonym: "hindlimb stylopodium" EXACT [OBOL:automatic] synonym: "proximal segment of free lower limb" EXACT [FMA:24967] synonym: "stylopod of hind limb" EXACT [OBOL:automatic] synonym: "stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "stylopod of lower limb" EXACT [] synonym: "thigh" EXACT [] synonym: "upper leg" EXACT HUMAN_PREFERRED [MA:0000052] xref: BTO:0001376 xref: CALOHA:TS-2039 xref: EFO:0001943 xref: EHDAA2:0002130 xref: EHDAA:5171 xref: EHDAA:6200 xref: EMAPA:17499 xref: FMA:24967 xref: GAID:50 xref: galen:Thigh xref: MA:0000052 xref: MESH:D013848 xref: NCIT:C33763 xref: SCTID:302544002 xref: UMLS:C0039866 {source="ncithesaurus:Thigh"} xref: VHOG:0000349 xref: Wikipedia:Thigh is_a: UBERON:0002472 ! stylopod is_a: UBERON:0008784 ! lower limb segment intersection_of: UBERON:0002472 ! stylopod intersection_of: part_of UBERON:0002103 ! hindlimb relationship: contributes_to_morphology_of UBERON:0002103 ! hindlimb relationship: has_skeleton UBERON:0015052 ! femur endochondral element relationship: part_of UBERON:0000978 {source="MA"} ! leg property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4b/Gray1238.png" xsd:anyURI property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000349", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group." xsd:string {seeAlso="https://github.com/obophenotype/uberon/issues/61"} [Term] id: UBERON:0000377 name: maxillary nerve namespace: uberon def: "The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses." [MP:0009799, Wikipedia:Maxillary_nerve] subset: human_reference_atlas subset: pheno_slim synonym: "maxillary division [V2]" EXACT [FMA:52724] synonym: "maxillary division [Vb]" EXACT [FMA:52724] synonym: "maxillary division of fifth cranial nerve" EXACT [FMA:52724] synonym: "maxillary division of trigeminal nerve (Vb; V2)" EXACT [FMA:52724] synonym: "maxillary nerve [V2]" EXACT [FMA:52724] synonym: "maxillary nerve [Vb]" EXACT [FMA:52724] synonym: "n. maxillaris" RELATED LATIN [Wikipedia:Maxillary_nerve] synonym: "nervus maxillaris" RELATED [BTO:0001378] synonym: "nervus maxillaris (Vb; V2)" EXACT [FMA:52724] synonym: "nervus maxillaris [v2]" EXACT LATIN [FMA:52724, FMA:TA] synonym: "nervus maxillaris [vb]" EXACT LATIN [FMA:52724, FMA:TA] synonym: "ramus maxillaris (ramus V2)" EXACT [AAO:0010670] synonym: "second division of fifth cranial nerve" EXACT [FMA:52724] synonym: "second division of trigeminal nerve" EXACT [FMA:52724] synonym: "trigeminal nerve maxillary division" RELATED [EMAPA:17799] synonym: "trigeminal V nerve maxillary division" EXACT [MA:0001103] xref: AAO:0010670 xref: BTO:0001378 xref: EHDAA2:0002087 xref: EMAPA:17799 xref: FMA:52724 xref: GAID:836 xref: MA:0001103 xref: MESH:D008442 xref: SCTID:280211001 xref: VHOG:0001346 xref: Wikipedia:Maxillary_nerve is_a: UBERON:0011779 ! nerve of head region relationship: branching_part_of UBERON:0001645 ! trigeminal nerve relationship: part_of UBERON:0001645 ! trigeminal nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a9/Gray779.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Medial ramus (sensory) of the trigeminal nerve.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010670", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000002 "relationship loss: part_of trunk maxillary-mandibularis (AAO:0010669)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010670", ontology="AAO"} [Term] id: UBERON:0000378 name: tongue muscle namespace: uberon def: "The muscular portion of the tongue." [MP:0004136, Wikipedia:Muscles_of_tongue] subset: pheno_slim synonym: "muscle of tongue" EXACT [FMA:46689] synonym: "muscle organ of tongue" EXACT [OBOL:accepted] synonym: "musculi linguae" RELATED LATIN [Wikipedia:Muscles_of_tongue] synonym: "skeletal muscle tissue of tongue" EXACT [OBOL:automatic] synonym: "tongue skeletal muscle" EXACT [OBOL:automatic] synonym: "tongue skeletal muscle tissue" EXACT [OBOL:automatic] xref: BTO:0001386 xref: EHDAA2:0002065 xref: EHDAA:9146 xref: EMAPA:17883 xref: FMA:46689 xref: MA:0001596 xref: NCIT:C49301 xref: NCIT:C52707 xref: SCTID:244781004 xref: UMLS:C0448325 {source="ncithesaurus:Tongue_Muscle"} xref: UMLS:C1710437 {source="ncithesaurus:Tongue_Skeletal_Muscle_Tissue"} xref: VHOG:0001390 xref: Wikipedia:Muscles_of_tongue is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010959 ! craniocervical muscle is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to_part_of UBERON:0001723 ! tongue union_of: UBERON:0001575 ! extrinsic muscle of tongue union_of: UBERON:0001576 ! intrinsic muscle of tongue relationship: attaches_to_part_of UBERON:0001723 ! tongue relationship: contributes_to_morphology_of UBERON:0001723 ! tongue relationship: develops_from UBERON:0005594 {source="FEED:rd", source="ISBN:1607950324"} ! head somite relationship: part_of UBERON:0000165 ! mouth property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c6/Gray1019.png" xsd:anyURI property_value: UBPROP:0000003 "The lamprey head contains another group of muscles, the epi- and hypo-branchial muscles (EBM and HBM), derivatives of anterior trunk myotomes. (...) The origin and the migration pattern of HBM precursors are very similar to that of the gnathostome MPP, especially to that of the tongue muscle precursors. Other evidence of homology of lamprey HBM to the gnathostome tongue muscle is that HBM is innervated by the nerve termed the hypoglossal nerve based on its morphological position associated with the head/trunk interface. (...) The HBM-specific expression of the LampPax3/7 gene is consistent with the homology of this muscle to the gnathostome tongue muscle, or to the hypobranchial series as a whole (including the infrahyoid and possibly the diaphragm in mammals).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001390", ontology="VHOG", source="DOI:10.1002/dvdy.20587 Kusakabe R, Kuratani S, Evolution and developmental patterning of the vertebrate skeletal muscles: perspectives from the lamprey. Developmental Dynamics (2005)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000379 name: tracheal mucosa namespace: uberon def: "A mucosa that is part of a respiratory airway." [OBOL:automatic] synonym: "mucosa of organ of trachea" EXACT [OBOL:automatic] synonym: "mucosa of organ of windpipe" EXACT [OBOL:automatic] synonym: "mucosa of trachea" EXACT [OBOL:automatic] synonym: "mucosa of windpipe" EXACT [OBOL:automatic] synonym: "mucous membrane of trachea" EXACT [FMA:7471, OBOL:automatic] synonym: "mucous membrane of windpipe" EXACT [OBOL:automatic] synonym: "organ mucosa of trachea" EXACT [OBOL:automatic] synonym: "organ mucosa of windpipe" EXACT [OBOL:automatic] synonym: "trachea mucosa" EXACT [OBOL:automatic] synonym: "trachea mucosa of organ" EXACT [OBOL:automatic] synonym: "trachea mucous membrane" EXACT [OBOL:automatic] synonym: "trachea organ mucosa" EXACT [OBOL:automatic] synonym: "tracheal mucous membrane" EXACT [FMA:7471] synonym: "tunica mucosa (tracheae)" EXACT [FMA:7471] synonym: "tunica mucosa tracheae" EXACT LATIN [FMA:7471, FMA:TA] synonym: "windpipe mucosa" EXACT [OBOL:automatic] synonym: "windpipe mucosa of organ" EXACT [OBOL:automatic] synonym: "windpipe mucous membrane" EXACT [OBOL:automatic] synonym: "windpipe organ mucosa" EXACT [OBOL:automatic] xref: BTO:0001390 xref: FMA:7471 xref: SCTID:660006 is_a: UBERON:0004785 ! respiratory system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001005 ! respiratory airway relationship: part_of UBERON:0001005 ! respiratory airway [Term] id: UBERON:0000383 name: musculature of body namespace: uberon def: "The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]." [VSAO:0000033] subset: efo_slim subset: human_reference_atlas subset: pheno_slim synonym: "muscle system" EXACT [] synonym: "muscle system of body" EXACT [] synonym: "muscular system" EXACT [FMA:72954] synonym: "musculature system" EXACT [BILA:0000088] synonym: "muskelsystem" RELATED [BTO:0001485] synonym: "set of all muscles" EXACT [FMA:72954] synonym: "set of muscles of body" EXACT [FMA:72954] synonym: "vertebrate muscular system" EXACT [BTO:0001369] xref: AAO:0000307 xref: BILA:0000088 xref: BTO:0001369 xref: BTO:0001485 xref: EFO:0000801 xref: EMAPA:35578 xref: FMA:72954 xref: MA:0002888 xref: MAT:0000025 xref: MIAA:0000025 xref: VSAO:0000033 xref: XAO:0004042 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 ! organ system subdivision intersection_of: UBERON:0011216 ! organ system subdivision intersection_of: composed_primarily_of UBERON:0001015 ! musculature relationship: capable_of GO:0003012 ! muscle system process relationship: composed_primarily_of UBERON:0001015 ! musculature relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: editor_note "consider whether this should be restricted to skeletal musculature. See https://github.com/obophenotype/uberon/issues/77" xsd:string property_value: RO:0002161 NCBITaxon:6040 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical system that consists of the muscles of the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000033", ontology="VSAO", source="VSAO:curator"} property_value: UBPROP:0000012 "we place the MA term musculature here, rather than under uberon:musculature, as this seems more appropriate given the structure of MA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0000389 name: lens cortex namespace: uberon def: "Tissue that surrounds the lens nucleus." [http://www.thefreedictionary.com/lens+cortex] subset: human_reference_atlas synonym: "cortex of lens" EXACT [FMA:58970] xref: BTO:0001632 xref: CALOHA:TS-0542 xref: FMA:58970 xref: MESH:D007904 xref: SCTID:280626006 is_a: UBERON:0000479 ! tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000479 ! tissue intersection_of: surrounds UBERON:0000390 ! lens nucleus relationship: develops_from UBERON:0005614 ! lens anterior epithelium relationship: part_of UBERON:0000965 ! lens of camera-type eye relationship: surrounds UBERON:0000390 ! lens nucleus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000390 name: lens nucleus namespace: uberon def: "The core of the crystalline lens, surrounded by the cortex." [BTO:0001633] subset: human_reference_atlas synonym: "nucleus of lens" EXACT [FMA:58971] xref: BTO:0001633 xref: FMA:58971 xref: MESH:D007907 xref: SCTID:280628007 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034944 ! zone of organ intersection_of: UBERON:0034944 ! zone of organ intersection_of: surrounded_by UBERON:0000389 ! lens cortex relationship: develops_from UBERON:0005614 ! lens anterior epithelium relationship: part_of UBERON:0000965 ! lens of camera-type eye relationship: surrounded_by UBERON:0000389 ! lens cortex property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000397 name: colonic epithelium namespace: uberon def: "An epithelium that is part of a colon [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: vertebrate_core synonym: "colon epithelial tissue" EXACT [OBOL:automatic] synonym: "colon epithelium" EXACT [FMA:17302, OBOL:automatic] synonym: "epithelial tissue of colon" EXACT [OBOL:automatic] synonym: "epithelial tissue of large bowel" EXACT [OBOL:automatic] synonym: "epithelium of colon" EXACT [OBOL:automatic] synonym: "epithelium of large bowel" EXACT [OBOL:automatic] synonym: "large bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "large bowel epithelium" EXACT [OBOL:automatic] synonym: "posterior intestine epithelium" EXACT [ZFA:0005128] xref: BTO:0001709 xref: CALOHA:TS-0163 xref: EMAPA:18941 xref: FMA:17302 xref: MA:0003195 xref: SCTID:42978003 xref: TAO:0005128 xref: ZFA:0005128 is_a: UBERON:0001278 ! epithelium of large intestine intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Intestinal epithelium which lines the lumen of the posterior intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005128", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0000398 name: cartilage tissue of sternum namespace: uberon def: "Any portion of cartilage tissue that is part of the sternum." [https://orcid.org/0000-0002-6601-2165] comment: Examples: cartilage of manubrium, cartilage of xiphoid process synonym: "cartilage of sternum" EXACT [FMA:32567] xref: FMA:32567 is_a: UBERON:0002418 ! cartilage tissue is_a: UBERON:0003837 ! thoracic segment connective tissue intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0000975 ! sternum relationship: part_of UBERON:0000975 ! sternum [Term] id: UBERON:0000402 name: nasal vestibule namespace: uberon def: "The nasal vestibule is the most anterior part of the nasal cavity. It's enclosed by the cartilages of nose and lined by the same epithelium of the skin. The other part of the nasal cavity, which is lined by the respiratory epithelium, is called nasal cavity proper. [WP,unvetted]." [Wikipedia:Nasal_vestibule] synonym: "vestibular part of nasal cavity" EXACT [FMA:59644] synonym: "vestibulum nasale" RELATED [BTO:0001761] synonym: "vestibulum nasi" RELATED LATIN [BTO:0001761, Wikipedia:Nasal_vestibule] xref: BTO:0001761 xref: CALOHA:TS-0660 xref: FMA:59644 xref: SCTID:278940000 xref: Wikipedia:Nasal_vestibule is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001707 ! nasal cavity property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7c/Gray994.png" xsd:anyURI [Term] id: UBERON:0000409 name: serous gland namespace: uberon def: "A gland in which the principal secretory cells are serous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] subset: organ_slim subset: pheno_slim xref: BTO:0001837 xref: EMAPA:37950 {source="MA:th"} xref: FMA:62889 xref: Wikipedia:Serous_gland is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: has_part CL:0000313 ! serous secreting cell relationship: has_part CL:0000313 ! serous secreting cell relationship: has_part UBERON:0013232 ! serous acinus relationship: produces UBERON:0007794 ! secretion of serous gland property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI property_value: UBPROP:0000001 "glands that secrete watery albuminous material that often contains enzymes[MP:0008052]." xsd:string {source="MP:0008052"} [Term] id: UBERON:0000410 name: bronchial mucosa namespace: uberon def: "A mucosa that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi mucosa" EXACT [OBOL:automatic] synonym: "bronchi mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchi mucous membrane" EXACT [OBOL:automatic] synonym: "bronchi organ mucosa" EXACT [OBOL:automatic] synonym: "bronchial trunk mucosa" EXACT [OBOL:automatic] synonym: "bronchial trunk mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchial trunk mucous membrane" EXACT [OBOL:automatic] synonym: "bronchial trunk organ mucosa" EXACT [OBOL:automatic] synonym: "bronchus mucosa" EXACT [OBOL:automatic] synonym: "bronchus mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchus mucous membrane" EXACT [OBOL:automatic] synonym: "bronchus organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bronchi" EXACT [OBOL:automatic] synonym: "mucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "mucosa of bronchus" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchi" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchial trunk" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchus" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchi" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchial trunk" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchus" EXACT [FMA:62652, OBOL:automatic] synonym: "organ mucosa of bronchi" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchus" EXACT [OBOL:automatic] synonym: "tunica mucosa bronchi" EXACT LATIN [FMA:62652, FMA:TA] xref: BTO:0001846 xref: FMA:62652 xref: SCTID:30802009 is_a: UBERON:0000379 ! tracheal mucosa is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 ! bronchus [Term] id: UBERON:0000414 name: mucous gland namespace: uberon def: "A gland in which the principal secretory cells are mucus secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] subset: organ_slim synonym: "glandula mucosa" EXACT LATIN [Wikipedia:Mucous_gland] synonym: "muciparous gland" RELATED [BTO:0001979] synonym: "mucous secreting gland" RELATED [] synonym: "mucus gland" RELATED [] synonym: "mucus-secreting gland" RELATED [] xref: AAO:0010601 xref: BTO:0001979 xref: EMAPA:37913 {source="MA:th"} xref: FMA:62888 xref: Wikipedia:Mucous_gland is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: has_part CL:0000319 ! mucus secreting cell relationship: capable_of GO:0070254 ! mucus secretion relationship: has_part CL:0000319 ! mucus secreting cell relationship: produces UBERON:0000912 ! mucus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray1021.png" xsd:anyURI property_value: UBPROP:0000008 "In frogs and salamanders, this is the smaller of the two types of gland, the other being the granular (poison) gland. In these species the mucous gland is a cluster of cells that release secretion into a common duct[Kardong]" xsd:string {scope="NCBITaxon:8292", source="ISBN:0073040584"} [Term] id: UBERON:0000415 name: artery wall namespace: uberon def: "An anatomical wall that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "arterial wall" EXACT [FMA:14155] synonym: "wall of artery" EXACT [FMA:14155] xref: BTO:0002009 xref: FMA:14155 xref: galen:ArterialWall is_a: UBERON:0035965 ! wall of blood vessel intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0001637 ! artery [Term] id: UBERON:0000440 name: trabecula namespace: uberon def: "A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]." [GO:0060343, Wikipedia:Trabecula] subset: grouping_class subset: pheno_slim synonym: "trabeculae" EXACT PLURAL [] xref: BTO:0002501 xref: FMA:85273 xref: Wikipedia:Trabecula is_a: UBERON:0000064 ! organ part relationship: has_part UBERON:0002384 ! connective tissue relationship: has_quality PATO:0001873 ! cylindrical property_value: UBPROP:0000007 "trabecular" xsd:string [Term] id: UBERON:0000442 name: right testicular vein namespace: uberon def: "A vein that drains the left pampiniform plexus and empties into the left renal vein." [Dorlands_Medical_Dictionary:MerckSource] subset: human_reference_atlas synonym: "right spermatic vein" EXACT [MA:0002220] synonym: "vena testicularis (adrenalis) dextra" EXACT [FMA:14341] synonym: "vena testicularis dextra" RELATED [BTO:0002679] synonym: "vena testicularis sinistra" RELATED [BTO:0002680] xref: BTO:0002679 xref: EMAPA:37383 {source="MA:th"} xref: FMA:14341 xref: MA:0002220 xref: NCIT:C52697 xref: SCTID:53500001 is_a: UBERON:0001144 ! testicular vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: drains UBERON:0004534 ! right testis relationship: connected_to UBERON:0001142 ! left renal vein relationship: drains UBERON:0004534 ! right testis relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000443 name: left testicular vein namespace: uberon def: "A vein that drains the right pampiniform plexus and empties into the inferior vena cava." [Dorlands_Medical_Dictionary:MerckSource] subset: human_reference_atlas synonym: "left spermatic vein" EXACT [MA:0002219] synonym: "vena testicularis dextra" RELATED [BTO:0002679] synonym: "vena testicularis sinistra" RELATED [BTO:0002680] xref: BTO:0002680 xref: EMAPA:37167 {source="MA:th"} xref: FMA:14345 xref: MA:0002219 xref: NCIT:C52696 xref: SCTID:90988008 is_a: UBERON:0001144 ! testicular vein intersection_of: UBERON:0001144 ! testicular vein intersection_of: drains UBERON:0004533 ! left testis relationship: connected_to UBERON:0001142 ! left renal vein relationship: drains UBERON:0004533 ! left testis relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0000456 name: secretion of exocrine gland namespace: uberon alt_id: UBERON:0006540 def: "A portion of organism substance that is produced by exocrine glands." [http://orcid.org/0000-0002-6601-2165] synonym: "bodily secretion" EXACT [MESH:D012634] synonym: "exocrine gland fluid" RELATED [] synonym: "exocrine gland fluid or secretion" RELATED [] synonym: "exocrine gland fluid/secretion" EXACT [MA:0002504] synonym: "exocrine gland secretion" RELATED [] synonym: "external secretion" RELATED [BTO:0002977] synonym: "secreted substance" EXACT [] synonym: "secretion" BROAD [FMA:9675] xref: AEO:0001005 xref: BTO:0002977 xref: BTO:0002979 xref: EMAPA:36535 xref: FMA:9675 xref: galen:Secretion xref: MA:0002504 xref: MESH:D012634 xref: NCIT:C34062 xref: UMLS:C1516992 {source="ncithesaurus:Exocrine_Gland_Fluid_or_Secretion"} is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0002365 ! exocrine gland relationship: produced_by UBERON:0002365 ! exocrine gland property_value: UBPROP:0000012 "BTO has two distunct classes, with exocrine glandular secretion a subtype of secretion - however, all examples in BTO directly under secretion appear to be exocrine gland secretions" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0000457 name: cavernous artery namespace: uberon def: "Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses." [BTO:0002996] synonym: "cavernous branch of cavernous part of internal carotid artery" EXACT [FMA:70527] synonym: "ramus sinus cavernosi (pars cavernosa) (arteria carotis interna)" EXACT LATIN [FMA:70527, FMA:TA] xref: BTO:0002996 xref: FMA:70527 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: branching_part_of UBERON:0001532 ! internal carotid artery intersection_of: supplies UBERON:0001675 ! trigeminal ganglion relationship: branching_part_of UBERON:0001532 ! internal carotid artery relationship: part_of UBERON:0001532 ! internal carotid artery relationship: supplies UBERON:0001675 ! trigeminal ganglion [Term] id: UBERON:0000459 name: uterine wall namespace: uberon def: "An anatomical wall that is part of a uterus [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of uterus" EXACT [OBOL:automatic] synonym: "uterus anatomical wall" EXACT [OBOL:automatic] synonym: "uterus wall" EXACT [OBOL:automatic] synonym: "wall of uterus" EXACT [OBOL:automatic] xref: BTO:0003083 xref: FMA:17560 xref: SCTID:245485002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus [Term] id: UBERON:0000463 name: organism substance namespace: uberon def: "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: pheno_slim subset: upper_level synonym: "body fluid or substance" EXACT [MA:0002450] synonym: "body substance" EXACT [FMA:9669] synonym: "organism substance" EXACT [CARO:0000004] synonym: "portion of body substance" EXACT [FMA:9669] synonym: "portion of organism substance" EXACT [ZFA:0001487] xref: AAO:0010839 xref: AEO:0000004 xref: BILA:0000004 xref: CALOHA:TS-2101 xref: CARO:0000004 xref: EHDAA2:0003004 xref: EMAPA:35178 xref: FBbt:00007019 xref: FMA:9669 xref: galen:BodySubstance xref: HAO:0000004 xref: MA:0002450 xref: NCIT:C13236 xref: SPD:0000008 xref: TAO:0001487 xref: TGMA:0001824 xref: VHOG:0001726 xref: XAO:0004001 xref: ZFA:0001487 is_a: UBERON:0000465 ! material anatomical entity relationship: has_quality PATO:0002198 ! quality of a substance relationship: part_of UBERON:0000468 {notes="this relationship may be too strong and may be weakened in future"} ! multicellular organism property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000464 name: anatomical space namespace: uberon def: "Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level synonym: "anatomical spaces" RELATED PLURAL [ZFA:0001643] synonym: "lumen" BROAD [] synonym: "lumen space" EXACT [] synonym: "space" BROAD [] xref: AAO:0010110 xref: AEO:0000005 xref: BILA:0000005 xref: CARO:0000005 xref: EHDAA2:0003005 xref: FBbt:00007017 xref: FMA:5897 xref: HAO:0000005 xref: NCIT:C94478 xref: TAO:0001668 xref: TGMA:0001825 xref: UMLS:C0524461 {source="ncithesaurus:Lumen_Space"} xref: VHOG:0001728 xref: XAO:0003190 xref: ZFA:0001643 is_a: UBERON:0000466 ! immaterial anatomical entity relationship: surrounded_by UBERON:0000061 ! anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000465 name: material anatomical entity namespace: uberon def: "Anatomical entity that has mass." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level xref: AAO:0010264 xref: AEO:0000006 xref: BILA:0000006 xref: CARO:0000006 xref: EHDAA2:0003006 xref: FBbt:00007016 xref: FMA:67165 xref: HAO:0000006 xref: TAO:0001836 xref: TGMA:0001826 xref: VHOG:0001721 is_a: BFO:0000040 ! material entity is_a: UBERON:0001062 ! anatomical entity disjoint_from: UBERON:0000466 ! immaterial anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000466 name: immaterial anatomical entity namespace: uberon def: "Anatomical entity that has no mass." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level synonym: "immaterial physical anatomical entity" EXACT [FMA:67112] xref: AAO:0010265 xref: AEO:0000007 xref: BILA:0000007 xref: CARO:0000007 xref: EHDAA2:0003007 xref: FBbt:00007015 xref: FMA:67112 xref: HAO:0000007 xref: TAO:0001835 xref: TGMA:0001827 xref: VHOG:0001727 is_a: BFO:0000141 ! immaterial entity is_a: UBERON:0001062 ! anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000467 name: anatomical system namespace: uberon def: "Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function." [CARO:0000011] subset: common_anatomy subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "anatomical systems" RELATED PLURAL [ZFA:0001439] synonym: "body system" EXACT [BIRNLEX:14] synonym: "connected anatomical system" EXACT [CARO:0000011] synonym: "organ system" EXACT [] synonym: "system" BROAD [GO:0048731] xref: AAO:0000007 xref: AEO:0000011 xref: BILA:0000011 xref: BIRNLEX:14 xref: BSA:0000049 xref: CALOHA:TS-2088 xref: CARO:0000011 xref: EHDAA2:0003011 xref: EHDAA:392 xref: EMAPA:16103 xref: EV:0100000 xref: FBbt:00004856 xref: FMA:7149 xref: galen:AnatomicalSystem xref: HAO:0000011 xref: MA:0000003 xref: NCIT:C12919 xref: SCTID:278195005 xref: TAO:0001439 xref: TGMA:0001831 xref: UMLS:C0460002 {source="ncithesaurus:Organ_System"} xref: VHOG:0001725 xref: WBbt:0005746 xref: WBbt:0005763 xref: Wikipedia:Organ_system xref: XAO:0003002 xref: ZFA:0001439 is_a: UBERON:0000061 ! anatomical structure relationship: existence_starts_during_or_after UBERON:0000111 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! organogenesis stage relationship: has_part UBERON:0000062 ! organ relationship: part_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: seeAlso EHDAA2:0001330 [Term] id: UBERON:0000468 name: multicellular organism namespace: uberon def: "Anatomical structure that is an individual member of a species and consists of more than one cell." [CARO:0000012, http://orcid.org/0000-0001-9114-8737, Wikipedia:Multi-cellular_organism] subset: common_anatomy subset: efo_slim subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "body" RELATED [AEO:0000103, BIRNLEX:18, FMA:256135, NCIT:C13041] synonym: "Koerper" RELATED [BTO:0001489] synonym: "multi-cellular organism" EXACT [CARO:0000012] synonym: "organism" BROAD [FBbt:00000001, VHOG:0000671, WBbt:0007833] synonym: "whole body" RELATED [BTO:0001489] synonym: "whole organism" RELATED [FBbt:00000001] xref: AAO:0010026 xref: AEO:0000191 xref: BILA:0000012 xref: BIRNLEX:18 xref: BSA:0000038 xref: BTO:0000042 xref: CARO:0000012 xref: EFO:0002906 xref: EHDAA2:0003103 xref: EHDAA2:0003191 xref: EHDAA:1 xref: EMAPA:25765 xref: EV:0100016 xref: FBbt:00000001 xref: FMA:256135 xref: galen:Organism xref: HAO:0000012 xref: NCIT:C13041 xref: ncithesaurus:Whole_Organism xref: SCTID:243928005 xref: TADS:0000001 xref: TAO:0001094 xref: TGMA:0001832 xref: VHOG:0000671 xref: WBbt:0007833 xref: Wikipedia:Multi-cellular_organism xref: XAO:0003004 xref: ZFA:0001094 is_a: UBERON:0010000 ! multicellular anatomical structure property_value: editor_note "TODO - split body and mc organism? body continues after death stage" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000007 "organismal" xsd:string [Term] id: UBERON:0000471 name: compound organ component namespace: uberon def: "Multi-tissue structure that is part of a compound organ." [CARO:0000019, http://orcid.org/0000-0001-9114-8737] subset: upper_level synonym: "compound organ components" RELATED PLURAL [ZFA:0001489] xref: AAO:0010017 xref: AEO:0000019 xref: BILA:0000019 xref: CARO:0000019 xref: EHDAA2:0003019 xref: HAO:0000019 xref: TAO:0001489 xref: TGMA:0001835 xref: XAO:0003039 xref: ZFA:0001489 is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of UBERON:0003103 ! compound organ property_value: IAO:0000232 "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string [Term] id: UBERON:0000473 name: testis namespace: uberon alt_id: UBERON:0002117 def: "A gonad of a male animal. A gonad produces and releases sperm." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gonad of male genitalia" EXACT [OBOL:automatic] synonym: "gonad of male reproductive system" EXACT [OBOL:automatic] synonym: "male gonad" EXACT [OBOL:automatic] synonym: "orchis" RELATED [BTO:0001363] synonym: "testes" RELATED PLURAL [] synonym: "testicle" EXACT [FMA:7210] synonym: "testiculus" RELATED LATIN [BTO:0001363] xref: AAO:0000606 xref: BILA:0000124 xref: BSA:0000085 xref: BTO:0001363 xref: CALOHA:TS-1030 xref: EFO:0000984 xref: EHDAA2:0002007 xref: EHDAA:8146 xref: EMAPA:17972 xref: EV:0100102 xref: FBbt:00004928 xref: FMA:7210 xref: GAID:396 xref: galen:Testis xref: HAO:0001007 xref: MA:0000411 xref: MAT:0000132 xref: MESH:D013737 xref: MIAA:0000132 xref: NCIT:C12412 xref: SCTID:181431007 xref: TAO:0000598 xref: UMLS:C0039597 {source="ncithesaurus:Testis"} xref: VHOG:0000252 xref: WBbt:0006794 xref: Wikipedia:Testis xref: XAO:0000157 xref: ZFA:0000598 is_a: UBERON:0000991 ! gonad is_a: UBERON:0003135 ! male reproductive organ intersection_of: UBERON:0000991 ! gonad intersection_of: part_of UBERON:0000079 ! male reproductive system disjoint_from: UBERON:0000992 ! ovary disjoint_from: UBERON:0009117 ! indifferent gonad relationship: develops_from UBERON:0009117 ! indifferent gonad relationship: in_lateral_side_of UBERON:0000468 {gci_relation="part_of", gci_filler="NCBITaxon:7742", notes="vertebrates"} ! multicellular organism property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c3/Gray1144.png" xsd:anyURI property_value: UBPROP:0000001 "Male reproductive organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000598", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "(...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000252", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007), DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "testicular" xsd:string property_value: UBPROP:0000008 "The testes are descended in metatherian and eutherian mammals, first transabdominally, then inguinoscrotally" xsd:string {source="ISBN:0123971756", taxon="NCBITaxon:40674"} [Term] id: UBERON:0000474 name: female reproductive system namespace: uberon def: "The organs and associated structures associated with bearing offspring in a female animal." [http://orcid.org/0000-0002-6601-2165, MP:0001119, Wikipedia:Female_genitalia] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "female genital system" RELATED [] synonym: "female genital tract" RELATED [] synonym: "female genitalia" RELATED [] synonym: "female genitals" RELATED PLURAL [XAO:0000156] synonym: "female organism genitalia" EXACT [OBOL:automatic] synonym: "female organism reproductive system" EXACT [OBOL:automatic] synonym: "female reproductive tract" RELATED [MA:0000381] synonym: "genitalia of female organism" EXACT [OBOL:automatic] synonym: "gynaecological tissue" RELATED [BTO:0000083] synonym: "reproductive system of female organism" EXACT [OBOL:automatic] synonym: "systema genitale femininum" RELATED [BTO:0000083] xref: BTO:0000083 xref: CALOHA:TS-1303 xref: EFO:0000969 xref: EHDAA2:0000506 xref: EHDAA:8116 xref: EMAPA:17959 xref: EV:0100110 xref: FBbt:00004864 xref: FMA:45663 xref: GAID:364 xref: HAO:0000324 xref: MA:0000381 xref: MESH:D005836 xref: MIAA:0000028 xref: NCIT:C12402 xref: SCTID:361386004 xref: TGMA:0000635 xref: UMLS:C0700038 {source="ncithesaurus:Female_Reproductive_System"} xref: VHOG:0000726 xref: Wikipedia:Female_genitalia xref: WikipediaCategory:Female_reproductive_system xref: XAO:0000156 is_a: UBERON:0000990 ! reproductive system intersection_of: UBERON:0000990 ! reproductive system intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0003100 ! female organism property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI property_value: UBPROP:0000003 "By far, sexual reproduction is the more common pattern among living vertebrate forms and its widespread occurrence suggests that it is the plesiomorphic, or primitive, reproductive mode among the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000726", ontology="VHOG", source="ISBN:978-0792383369 Lombardi J, Comparative vertebrate reproduction (1998) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000475 name: organism subdivision namespace: uberon def: "Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument." [CARO:0000032, CARO:DOS, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: efo_slim subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "anatomic region" EXACT [MA:0002433] synonym: "body part" RELATED [] synonym: "body region" RELATED [FMA:7153] synonym: "cardinal body part" RELATED [FMA:7153] xref: AAO:0010053 xref: AEO:0000032 xref: BILA:0000032 xref: BIRNLEX:7 xref: CALOHA:TS-2084 xref: CARO:0000032 xref: EFO:0000808 xref: EHDAA2:0003032 xref: EMAPA:36031 xref: FBbt:00007009 xref: FMA:7153 xref: galen:BodyPart xref: HAO:0000032 xref: MA:0002433 xref: MAT:0000293 xref: MESH:D001829 xref: MIAA:0000293 xref: NCIT:C32221 xref: TAO:0001308 xref: TGMA:0001840 xref: UMLS:C0229962 {source="ncithesaurus:Body_Part"} xref: VHOG:0001758 xref: Wikipedia:Body_part xref: XAO:0003013 xref: ZFA:0001308 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: has_part UBERON:0000075 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! subdivision of skeletal system relationship: has_part UBERON:0034929 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! external soft tissue zone relationship: overlaps UBERON:0001009 {gci_filler="NCBITaxon:33213", gci_relation="in_taxon"} ! circulatory system relationship: overlaps UBERON:0001015 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! musculature relationship: overlaps UBERON:0001016 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! nervous system relationship: overlaps UBERON:0001434 {gci_filler="NCBITaxon:33213", gci_relation="in_taxon"} ! skeletal system relationship: overlaps UBERON:0002416 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! integumental system relationship: part_of UBERON:0000468 ! multicellular organism property_value: editor_note "Reflects CARO2. todo - check the inclusion of FMA 'cardinal body part here', and check child terms for consistency" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000476 name: acellular anatomical structure namespace: uberon def: "Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue." [http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: vertebrate_core synonym: "acellular anatomical structures" RELATED PLURAL [ZFA:0000382] xref: AAO:0010268 xref: AEO:0000040 xref: BILA:0000040 xref: CARO:0000040 xref: EHDAA2:0003040 xref: FBbt:00007013 xref: FMA:63863 xref: HAO:0000040 xref: TAO:0000382 xref: TGMA:0001841 xref: XAO:0003162 xref: ZFA:0000382 is_a: UBERON:0000061 ! anatomical structure disjoint_from: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000477 name: anatomical cluster namespace: uberon def: "Anatomical group whose component anatomical structures lie in close proximity to each other." [FBbt:00007277] subset: common_anatomy subset: upper_level xref: FBbt:00007277 xref: VHOG:0001737 is_a: UBERON:0034923 ! disconnected anatomical group property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000478 name: extraembryonic structure namespace: uberon def: "A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis." [CARO:DOS, http://orcid.org/0000-0001-9114-8737, https://cedar.bio.indiana.edu/trac/env/ontologies/ticket/279] comment: see also conceptus extraembryonic component in EHDAA2. subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "extra-embryonic structure" EXACT [] synonym: "extraembryonic structures" RELATED PLURAL [ZFA:0000020] synonym: "extraembryonic tissue" RELATED [] xref: AAO:0010020 xref: AEO:0000042 xref: BILA:0000042 xref: CALOHA:TS-2119 xref: CARO:0000042 xref: EHDAA2:0003042 xref: EHDAA:46 xref: FBbt:00005835 xref: FMA:85537 xref: HAO:0000042 xref: NCIT:C34055 xref: SCTID:314908006 xref: TAO:0000020 xref: TGMA:0001843 xref: UMLS:C1282438 {source="ncithesaurus:Extraembryonic_Structure"} xref: VHOG:0000292 xref: XAO:0004005 xref: ZFA:0000020 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: part_of UBERON:0016887 ! entire extraembryonic component relationship: existence_starts_and_ends_during UBERON:0000068 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! embryo stage relationship: part_of UBERON:0016887 ! entire extraembryonic component [Term] id: UBERON:0000479 name: tissue namespace: uberon def: "Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation." [CARO:0000043] subset: common_anatomy subset: pheno_slim subset: upper_level synonym: "portion of tissue" EXACT [CARO:0000043] synonym: "simple tissue" NARROW [AEO:0000043] synonym: "tissue portion" EXACT [] xref: AAO:0000607 xref: AAO:0010054 xref: AEO:0000043 xref: BILA:0000043 xref: BIRNLEX:19 xref: CALOHA:TS-2090 xref: CARO:0000043 xref: EHDAA2:0003043 xref: EMAPA:35868 xref: FBbt:00007003 xref: FMA:9637 xref: galen:Tissue xref: HAO:0000043 xref: MA:0003002 xref: MESH:D014024 xref: NCIT:C12801 xref: TAO:0001477 xref: TGMA:0001844 xref: UMLS:C0040300 {source="ncithesaurus:Tissue"} xref: VHOG:0001757 xref: WBbt:0005729 xref: XAO:0003040 xref: ZFA:0001477 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: has_part GO:0031012 ! extracellular matrix relationship: part_of UBERON:0000468 ! multicellular organism property_value: editor_note "changed label and definition to reflect CARO2" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000481 name: multi-tissue structure namespace: uberon def: "Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types." [CARO:0000055, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level synonym: "multi-tissue structures" RELATED PLURAL [ZFA:0001488] xref: AAO:0010048 xref: AEO:0000055 xref: BILA:0000055 xref: CARO:0000055 xref: EHDAA2:0003055 xref: FBbt:00007010 xref: HAO:0000055 xref: TAO:0001488 xref: TGMA:0001847 xref: VHOG:0001762 xref: XAO:0003037 xref: ZFA:0001488 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: has_part UBERON:0000479 ! tissue relationship: part_of NCBITaxon:6072 {gci_filler="NCBITaxon:6072", gci_relation="in_taxon"} ! Eumetazoa property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0000483 name: epithelium namespace: uberon def: "Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Epithelium] comment: Editor note: surface epithelium may contain non-epithelial cells, such as melanocytes, lymphocytes and dendritic cells, within the sheet of epithelial cells. Do we consider these part of the epithelium, or located-in it? subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "epithelial tissue" EXACT [] synonym: "portion of epithelium" EXACT [FMA:9639] xref: AAO:0000144 xref: AAO:0010055 xref: AEO:0000066 xref: BILA:0000066 xref: BTO:0000416 xref: CALOHA:TS-0288 xref: CARO:0000066 xref: EHDAA2:0003066 xref: EMAPA:32738 xref: FBbt:00007005 xref: FMA:9639 xref: GAID:402 xref: HAO:0000066 xref: MA:0003060 xref: MESH:D004848 xref: NCIT:C12710 xref: SCTID:31610004 xref: TAO:0001486 xref: UMLS:C0014609 {source="ncithesaurus:Epithelium"} xref: VHOG:0000387 xref: Wikipedia:Epithelium xref: XAO:0003045 xref: ZFA:0001486 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: composed_primarily_of CL:0000066 ! epithelial cell union_of: UBERON:0000486 ! multilaminar epithelium union_of: UBERON:0000490 ! unilaminar epithelium relationship: composed_primarily_of CL:0000066 ! epithelial cell relationship: has_part GO:0005911 ! cell-cell junction relationship: has_part UBERON:0005769 ! basement membrane of epithelium relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI property_value: UBPROP:0000003 "The two basic types of metazoan tissue are epithelial and connective. The simplest metazoans, and developmental stages of many primitive invertebrates, consist solely of these two layers. Thus, epithelial and connective tissues may be the primary (original) tissues of metazoans, and both are important in the functional organization of animals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000387", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.59", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "epithelial" xsd:string [Term] id: UBERON:0000484 name: simple cuboidal epithelium namespace: uberon def: "Unilaminar epithelium that consists of a single layer of cuboidal cells." [http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_cuboidal_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "epithelium simplex cuboideum" EXACT [] synonym: "simple cuboidal epithelia" RELATED PLURAL [ZFA:0001497] xref: AAO:0010064 xref: AEO:0000067 xref: BILA:0000067 xref: CARO:0000067 xref: EHDAA2:0003067 xref: FMA:45566 xref: HAO:0000067 xref: NCIT:C33553 xref: TAO:0001497 xref: UMLS:C0836134 {source="ncithesaurus:Simple_Cuboidal_Epithelium"} xref: Wikipedia:Simple_cuboidal_epithelium xref: XAO:0004009 xref: ZFA:0001497 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0010077 ! cuboidal epithelium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d0/Gray1133.png" xsd:anyURI property_value: editor_note "needs to be synchronized with CL - there is no distinct cuboidal cell in CL" xsd:string [Term] id: UBERON:0000485 name: simple columnar epithelium namespace: uberon def: "Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_columnar_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "columnar epithelium" BROAD [EHDAA2:0003068] synonym: "columnar epithlium" BROAD [AEO:0000068] synonym: "epithelium simplex columnare" EXACT [] synonym: "simple columnar epithelia" RELATED PLURAL [ZFA:0001496] synonym: "simple columnar epithelium" EXACT [] xref: AAO:0010063 xref: AEO:0000068 xref: BILA:0000068 xref: CARO:0000068 xref: EHDAA2_RETIRED:0003068 xref: FBbt:00007027 xref: FMA:45567 xref: HAO:0000068 xref: NCIT:C33552 xref: SCTID:32210007 xref: TAO:0001496 xref: UMLS:C0836135 {source="ncithesaurus:Simple_Columnar_Epithelium"} xref: Wikipedia:Simple_columnar_epithelium xref: XAO:0004008 xref: ZFA:0001496 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0012274 ! columnar epithelium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray1059.png" xsd:anyURI [Term] id: UBERON:0000486 name: multilaminar epithelium namespace: uberon def: "Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]." [FMA:FMA, http://orcid.org/0000-0001-9114-8737, Wikipedia:Stratified_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "laminated epithelium" RELATED [BTO:0002074] synonym: "stratified epithelium" EXACT [] xref: AAO:0010059 xref: AEO:0000069 xref: BILA:0000069 xref: BTO:0002074 xref: CARO:0000069 xref: EHDAA2:0003069 xref: FMA:45562 xref: HAO:0000069 xref: NCIT:C33622 xref: SCTID:309044005 xref: TAO:0001494 xref: UMLS:C0682575 {source="ncithesaurus:Stratified_Epithelium"} xref: Wikipedia:Stratified_epithelium xref: XAO:0004006 xref: ZFA:0001494 is_a: UBERON:0000483 ! epithelium property_value: UBPROP:0000001 "Epithelium that consists of more than one layer of epithelial cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000069", ontology="CARO", source="FMA:45562", source="http://orcid.org/0000-0001-9114-8737"} [Term] id: UBERON:0000487 name: simple squamous epithelium namespace: uberon def: "Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]." [FMA:45565, http://orcid.org/0000-0001-9114-8737, Wikipedia:Simple_squamous_epithelium] subset: uberon_slim subset: vertebrate_core synonym: "epithelium simplex squamosum" EXACT [] synonym: "simple squamous epithelia" RELATED PLURAL [ZFA:0001498] xref: AAO:0010066 xref: AEO:0000070 xref: BILA:0000070 xref: BTO:0002073 xref: CARO:0000070 xref: EHDAA2:0003070 xref: FMA:45565 xref: HAO:0000070 xref: NCIT:C13178 xref: TAO:0001498 xref: UMLS:C0836133 {source="ncithesaurus:Simple_Squamous_Epithelium"} xref: Wikipedia:Simple_squamous_epithelium xref: XAO:0004010 xref: ZFA:0001498 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0006914 ! squamous epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: has_part CL:0000076 ! squamous epithelial cell property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/8/8f/Illu_epithelium.jpg" xsd:anyURI property_value: UBPROP:0000001 "Unilaminar epithelium that consists of a single layer of squamous cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000070", ontology="CARO", source="FMA:45565", source="http://orcid.org/0000-0001-9114-8737"} [Term] id: UBERON:0000488 name: atypical epithelium namespace: uberon def: "Epithelium that consists of epithelial cells not arranged in one ore more layers." [http://orcid.org/0000-0001-9114-8737] subset: vertebrate_core synonym: "atypical epithelia" RELATED PLURAL [ZFA:0001493] synonym: "heterogenous epithelium" EXACT [] xref: AAO:0010057 xref: AEO:0000071 xref: BILA:0000071 xref: CARO:0000071 xref: EHDAA2:0003071 xref: FMA:61741 xref: HAO:0000071 xref: TAO:0001493 xref: XAO:0004004 xref: ZFA:0001493 is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0000489 name: cavitated compound organ namespace: uberon def: "Compound organ that contains one or more macroscopic anatomical spaces." [http://orcid.org/0000-0001-9114-8737] subset: organ_slim subset: upper_level synonym: "cavitated compound organs" RELATED PLURAL [ZFA:0001490] synonym: "cavitated organ" EXACT [FMA:55671] xref: AAO:0010016 xref: AEO:0000072 xref: BILA:0000072 xref: CARO:0000072 xref: EHDAA2:0003072 xref: FMA:55671 xref: HAO:0000072 xref: TAO:0001490 xref: TGMA:0001857 xref: VHOG:0001730 xref: XAO:0003165 xref: ZFA:0001490 is_a: UBERON:0003103 ! compound organ intersection_of: UBERON:0003103 ! compound organ intersection_of: has_part UBERON:0002553 ! anatomical cavity relationship: has_part UBERON:0002553 ! anatomical cavity property_value: IAO:0000232 "this class was introduced for consistency with CARO, however, it has yet to be used in this or other ontologies. It may be retired in the future" xsd:string [Term] id: UBERON:0000490 name: unilaminar epithelium namespace: uberon def: "Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]." [FMA:45561, http://orcid.org/0000-0001-9114-8737] subset: vertebrate_core synonym: "simple epithelium" EXACT [FMA:45561] synonym: "unilaminar epithelia" RELATED PLURAL [ZFA:0001495] xref: AAO:0010062 xref: AEO:0000073 xref: BILA:0000073 xref: BTO:0002073 xref: CARO:0000073 xref: EHDAA2:0003073 xref: FMA:45561 xref: HAO:0000073 xref: NCIT:C33554 xref: SCTID:309043004 xref: TAO:0001495 xref: UMLS:C0682574 {source="ncithesaurus:Simple_Epithelium"} xref: XAO:0004007 xref: ZFA:0001495 is_a: UBERON:0000483 ! epithelium property_value: editor_note "consider adding disjointness axiom between unilaminar and multilaminar - but note that this will render EHDAA2:0003244 (chorionic trophoblast) unsatisfiable" xsd:string property_value: UBPROP:0000001 "Epithelium that consists of a single layer of epithelial cells.[CARO]" xsd:string {date_retrieved="2012-06-20", external_class="CARO:0000073", ontology="CARO", source="FMA:45561", source="http://orcid.org/0000-0001-9114-8737"} [Term] id: UBERON:0000912 name: mucus namespace: uberon def: "Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water." [Wikipedia:Mucus] xref: CALOHA:TS-2144 xref: ENVO:02000040 xref: FMA:66938 xref: GAID:1164 xref: galen:Mucus xref: MESH:D009093 xref: NCIT:C13259 xref: UMLS:C0026727 {source="ncithesaurus:Mucus"} xref: Wikipedia:Mucus is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006314 ! bodily fluid relationship: has_part CHEBI:37395 ! mucopolysaccharide relationship: has_quality PATO:0000998 ! viscous relationship: produced_by UBERON:0000344 ! mucosa property_value: UBPROP:0000007 "mucoid" xsd:string property_value: UBPROP:0000007 "mucous" xsd:string [Term] id: UBERON:0000915 name: thoracic segment of trunk namespace: uberon def: "Subdivision of trunk that lies between the head and the abdomen." [http://orcid.org/0000-0002-6601-2165] subset: uberon_slim synonym: "anterior subdivision of trunk" RELATED [] synonym: "thorax" EXACT [MA:0000022] synonym: "upper body" RELATED [] synonym: "upper trunk" RELATED [FMA:259209] xref: EMAPA:35862 xref: FMA:259209 xref: MA:0000022 xref: SCTID:302551006 xref: Wikipedia:Thorax is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk is_a: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: has_skeleton UBERON:0014477 ! thoracic skeleton relationship: has_skeleton UBERON:0014477 ! thoracic skeleton property_value: IAO:0000232 "note that we use the slightly verbose term 'thoracic segment of trunk' to avoid confusuon with insect thorax. todo - taxonomic constraints. Also, in FMA 'thorax' is a synonym for chest" xsd:string property_value: RO:0002171 UBERON:0000026 property_value: RO:0002171 UBERON:0000033 property_value: RO:0002171 UBERON:0002417 [Term] id: UBERON:0000916 name: abdomen namespace: uberon def: "The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "abdominopelvic region" EXACT [FMA:9577] synonym: "abdominopelvis" EXACT [FMA:9577] synonym: "adult abdomen" RELATED [] synonym: "belly" RELATED [] synonym: "celiac region" RELATED [] xref: BTO:0000020 xref: CALOHA:TS-0001 xref: EFO:0000968 xref: EMAPA:35102 xref: EV:0100011 xref: FMA:9577 xref: GAID:16 xref: galen:Abdomen xref: MA:0000029 xref: MAT:0000298 xref: MESH:D000005 xref: MIAA:0000298 xref: SCTID:302553009 xref: Wikipedia:Abdomen is_a: UBERON:0009569 ! subdivision of trunk relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002417 {source="MA"} ! abdominal segment of trunk property_value: editor_note "Vertebrate specific. In arthropods 'abdomen' is the most distal section of the body which lies behind the thorax or cephalothorax. If need be we can introduce some grouping class" xsd:string property_value: UBPROP:0000007 "abdominal" xsd:string property_value: UBPROP:0000007 "celiac" xsd:string [Term] id: UBERON:0000922 name: embryo namespace: uberon def: "Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." [BTO:0000379, FB:FBrf0039741, FB:FBrf0041814, GO:0009790, Wikipedia:Embryo] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "developing organism" RELATED [BILA:0000056] synonym: "developmental tissue" RELATED [] synonym: "embryonic organism" EXACT [BILA:0000056] xref: AAO:0011035 xref: AEO:0000169 xref: BILA:0000056 xref: BSA:0000039 xref: BTO:0000379 xref: CALOHA:TS-0229 xref: EFO:0001367 xref: EHDAA2:0000002 xref: EHDAA2_RETIRED:0003236 xref: EHDAA:38 xref: EMAPA:16039 xref: FBbt:00000052 xref: FMA:69068 xref: GAID:963 xref: http://neurolex.org/wiki/Category\:Embryonic_organism xref: MAT:0000226 xref: MESH:D004622 xref: MIAA:0000019 xref: NCIT:C28147 xref: OGEM:000001 xref: SCTID:57991002 xref: UMLS:C0013935 {source="ncithesaurus:Embryo"} xref: VHOG:0001766 xref: Wikipedia:Embryo xref: XAO:0000113 xref: ZFA:0000103 is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_ends_with UBERON:0000068 ! embryo stage intersection_of: existence_starts_with UBERON:0000068 ! embryo stage relationship: existence_ends_with UBERON:0000068 ! embryo stage relationship: existence_starts_with UBERON:0000068 ! embryo stage property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/2/2d/Wrinkledfrog_embryos.jpg" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/503" xsd:anyURI property_value: UBPROP:0000007 "embryonic" xsd:string property_value: UBPROP:0000012 "Obsoleted in ZFA. Note that embryo is not classified as an embryonic structure - an embryonic structure is only the parts of an embryo" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0000923 name: germ layer namespace: uberon def: "A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm." [https://github.com/obophenotype/uberon/issues/203, Wikipedia:Germ_layer] comment: Classically the germ layers are ectoderm, mesoderm and endoderm. Alternatively: primary = ectoderm, endoderm; secondary=mesoderm; tertiary=dorsal mesoderm, NC[https://github.com/obophenotype/uberon/wiki/The-neural-crest] subset: uberon_slim subset: vertebrate_core synonym: "embryonic germ layer" RELATED [] synonym: "embryonic germ layers" RELATED [] synonym: "embryonic tissue" BROAD [FMA:69069] synonym: "germinal layer" EXACT [ncithesaurus:Germinal_Layer] synonym: "primary germ layer" NARROW [GO:0001704, ZFA:0001122] xref: AAO:0000480 xref: BILA:0000035 xref: BTO:0000556 xref: EMAPA:36033 xref: FBbt:00000110 xref: FMA:69069 xref: GAID:1303 xref: MESH:D005855 xref: NCIT:C12950 xref: NCIT:C54105 xref: TAO:0001122 xref: UMLS:C0920502 {source="ncithesaurus:Embryonic_Tissue"} xref: UMLS:C1708239 {source="ncithesaurus:Germinal_Layer"} xref: VHOG:0001223 xref: Wikipedia:Germ_layer xref: XAO:0003011 xref: ZFA:0001122 is_a: UBERON:0010316 ! germ layer / neural crest relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001223", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000924 name: ectoderm namespace: uberon def: "Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue." [Wikipedia:Ectoderm] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic ectoderm" EXACT [VHOG:0000153] xref: AAO:0000137 xref: BILA:0000036 xref: BTO:0000315 xref: CALOHA:TS-0216 xref: EFO:0000414 xref: EHDAA2:0000428 xref: EMAPA:16069 xref: EV:0100003 xref: FBbt:00000111 xref: FMA:69070 xref: GAID:1304 xref: MAT:0000155 xref: MAT:0000173 xref: MESH:D004475 xref: MIAA:0000173 xref: NCIT:C12703 xref: SCTID:362851007 xref: TAO:0000016 xref: UMLS:C0013574 {source="ncithesaurus:Ectoderm"} xref: VHOG:0000153 xref: Wikipedia:Ectoderm xref: XAO:0000001 xref: ZFA:0000016 is_a: UBERON:0000923 ! germ layer relationship: develops_from UBERON:0006601 ! presumptive ectoderm relationship: has_part CL:0000221 ! ectodermal cell relationship: immediate_transformation_of UBERON:0006601 {source="Bgee:AN"} ! presumptive ectoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray32.png" xsd:anyURI property_value: UBPROP:0000001 "Primary germ layer that is the outer of the embryonic germ layers and gives rise to epidermis and neural tissue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000137", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000153", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ectodermal" xsd:string [Term] id: UBERON:0000925 name: endoderm namespace: uberon def: "Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut." [Wikipedia:Endoderm] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "entoderm" RELATED DEPRECATED [DOI:10.5962/bhl.title.1013] xref: AAO:0000139 xref: BILA:0000038 xref: BTO:0000800 xref: CALOHA:TS-0273 xref: EFO:0002545 xref: EHDAA2:0000436 xref: EMAPA:16062 xref: EV:0100005 xref: FBbt:00000125 xref: FMA:69071 xref: GAID:1305 xref: MAT:0000175 xref: MESH:D004707 xref: MIAA:0000175 xref: NCIT:C12706 xref: SCTID:362855003 xref: TAO:0000017 xref: UMLS:C0014144 {source="ncithesaurus:Endoderm"} xref: VHOG:0000154 xref: Wikipedia:Endoderm xref: XAO:0000090 xref: ZFA:0000017 is_a: UBERON:0000923 ! germ layer relationship: develops_from UBERON:0006595 ! presumptive endoderm relationship: has_part CL:0000223 ! endodermal cell relationship: immediate_transformation_of UBERON:0006595 {source="Bgee:AN"} ! presumptive endoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c0/Endoderm2.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/df/Gray10.png" xsd:anyURI property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000154", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "endodermal" xsd:string [Term] id: UBERON:0000926 name: mesoderm namespace: uberon alt_id: UBERON:0003263 def: "The middle germ layer of the embryo, between the endoderm and ectoderm." [Wikipedia:Mesoderm] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic mesoderm" RELATED [VHOG:0000152] synonym: "entire mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165, SCTID:362854004] synonym: "mesodermal mantle" RELATED [] xref: AAO:0000304 xref: BILA:0000037 xref: BTO:0000839 xref: CALOHA:TS-0623 xref: EFO:0001981 xref: EHDAA2:0001128 xref: EHDAA:124 xref: EHDAA:160 xref: EHDAA:183 xref: EMAPA:16083 xref: EV:0100006 xref: FBbt:00000126 xref: FMA:69072 xref: GAID:522 xref: MAT:0000174 xref: MESH:D008648 xref: MIAA:0000174 xref: NCIT:C12750 xref: SCTID:362854004 xref: TAO:0000041 xref: UMLS:C0025485 {source="ncithesaurus:Mesoderm"} xref: VHOG:0000152 xref: Wikipedia:Mesoderm xref: XAO:0000050 xref: ZFA:0000041 is_a: UBERON:0000923 {notes="sometimes not considered primary"} ! germ layer relationship: develops_from UBERON:0006603 ! presumptive mesoderm relationship: has_part CL:0000222 ! mesodermal cell relationship: immediate_transformation_of UBERON:0006603 {source="Bgee:AN"} ! presumptive mesoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e8/Mesoderm.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:6040 property_value: UBPROP:0000001 "Primary germ layer that is the middle of the embryonic germ layers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000304", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The Bilateria are triploblastic (with true endoderm, mesoderm, and ectoderm) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000152", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) Limb development and evolution, p.722", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "mesodermal" xsd:string property_value: UBPROP:0000008 "sponges do not seem to have a mesoderm and accordingly Amphimedon lacks transcription factors involved in mesoderm development (Fkh, Gsc, Twist, Snail)[http://www.nature.com/nature/journal/v466/n7307/full/nature09201.html]. Mesoderm may not be homologous across verteberates" xsd:string {source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} [Term] id: UBERON:0000930 name: stomodeum namespace: uberon def: "Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/326, Wikipedia:Stomodeum] subset: grouping_class subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mouth pit" RELATED [EMAPA:16263] synonym: "mouth primordium" EXACT [XAO:0000269] synonym: "oral ectoderm" RELATED [ZFA:0001290, ZFIN:ZDB-PUB-100726-23] synonym: "oral pit" RELATED [EMAPA:16263] synonym: "primitive oral cavity" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "stomatodeum" EXACT [Wikipedia:Stomodeum] synonym: "stomodaeum" EXACT [] synonym: "stomodeal-hypophyseal primordium" BROAD [XAO:0000269] xref: BTO:0004224 xref: EHDAA2:0001929 xref: EMAPA:16263 xref: FBbt:00000439 xref: FMA:295846 xref: NCIT:C34306 xref: TAO:0001290 xref: TGMA:0000135 xref: UMLS:C1514977 {source="ncithesaurus:Stomodeum"} xref: Wikipedia:Stomodeum xref: XAO:0000269 xref: ZFA:0001290 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013522 ! subdivision of tube relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000924 ! ectoderm relationship: part_of UBERON:0035804 ! future mouth property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png" xsd:anyURI property_value: editor_note "consider indicating location. e.g. anterior. Note some AOs place this as part of oral opening, but it's not clear when this structure comes into existence" xsd:string property_value: UBPROP:0000001 "Anterior part of the embryonic alimentary canal formed as an invagination of the ectoderm; the future mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001290", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "the primordial mouth region of the developing head, initially a midline ectodermal depression between the forebrain bulge (cranially) and the heart bulge (caudally) and between the maxillary and mandibular components of the first pharyngeal arch; the stomodeum is separated from the anterior end of the foregut by the buccopharyngeal membrane; the mouth is developed partly from the stomodeum, and partly from the floor of the anterior portion of the foregut; the lips, teeth, and gums are formed from the walls of the stomodeum, but the tongue is developed in the floor of the pharynx" xsd:string {source="MP:0012522", taxon="NCBITaxon:40674"} property_value: UBPROP:0000007 "stomodeal" xsd:string property_value: UBPROP:0000008 "This class groups together disparate structures as all being the anterior part of the early metazoan digestive tract and precursor of the mouth. However, the developmental processes vary, so this class may be split in future. E.g. in mammals it is a rostral depression surrounded by prominences. Outgrowth of the prominences produces a stomodeal cavity." xsd:string [Term] id: UBERON:0000931 name: proctodeum namespace: uberon def: "Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract." [https://github.com/obophenotype/uberon/issues/685, https://sourceforge.net/p/fbbtdv/tickets/52, ZFA:0000066] subset: uberon_slim synonym: "amnioproctodeal invagination" NARROW [FBbt:00000123] synonym: "anal pit" RELATED [VHOG:0000139] synonym: "anus porus" RELATED [XAO:0001019] synonym: "embryonic proctodaeum" EXACT [] synonym: "proctodaeum" EXACT [] xref: AAO:0011087 xref: EHDAA2:0000121 xref: EMAPA:25038 xref: FBbt:00000123 xref: NCIT:C34278 xref: TAO:0000066 xref: UMLS:C0231054 {source="ncithesaurus:Proctodeum"} xref: VHOG:0000139 xref: Wikipedia:Proctodeum xref: XAO:0001019 xref: ZFA:0000066 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0016566 {source="EHDAA2"} ! pit relationship: develops_from UBERON:0000924 ! ectoderm relationship: has_potential_to_develop_into UBERON:0001353 ! anal region relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/ANiknejad relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/dosumis relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mmc46 relationship: located_in UBERON:0012469 {source="EHDAA2"} ! external anal region relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0007026 ! presumptive gut property_value: editor_note "removed WBbt:0006795 'proctodeum' - junction between the alimentary and genital tracts in the male." xsd:string property_value: seeAlso "https://github.com/obophenotype/uberon/issues/685" xsd:anyURI property_value: UBPROP:0000001 "An inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000066", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Inward fold on the surface of the embryonic ectoderm that develops into part of the anal passage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011087", ontology="AAO", source="ZFA:0000066"} property_value: UBPROP:0000007 "proctodeal" xsd:string [Term] id: UBERON:0000933 name: chordate pharyngeal muscle namespace: uberon def: "A muscle that acts on the pharynx[WP, vetted]." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Pharyngeal_muscles] comment: Innervation notes: They are innervated by the pharyngeal branch of the Vagus nerve (CN X) with the exception of the stylopharyngeus muscle which is innervated by the glossopharyngeal nerve (CN IX).[WP] subset: efo_slim subset: pheno_slim synonym: "branchial muscle" EXACT [ZFA:0000172] synonym: "branchial muscles" RELATED PLURAL [TAO:0000172] synonym: "muscle of pharynx" EXACT [] synonym: "muscle organ of pharynx" EXACT [OBOL:automatic] synonym: "musculi pharyngis" RELATED LATIN [Wikipedia:Pharyngeal_muscles] synonym: "musculus pharyngis" RELATED [BTO:0001048] synonym: "pharyngeal muscle" EXACT [] synonym: "pharynx muscle" EXACT [] synonym: "pharynx muscle organ" EXACT [OBOL:automatic] synonym: "tunica muscularis pharyngis" RELATED LATIN [Wikipedia:Pharyngeal_muscles] xref: BTO:0001048 xref: EFO:0003504 xref: EMAPA:18963 xref: FMA:46619 xref: GAID:154 xref: MA:0001797 xref: MESH:D010609 xref: NCIT:C13075 xref: SCTID:244798004 xref: TAO:0000172 xref: UMLS:C0031346 {source="ncithesaurus:Pharyngeal_Muscle"} xref: Wikipedia:Pharyngeal_muscles xref: ZFA:0000172 is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0004467 ! musculature of pharynx relationship: contributes_to_morphology_of UBERON:0001015 ! musculature relationship: part_of UBERON:0004467 ! musculature of pharynx property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/35/Gray1030.png" xsd:anyURI property_value: UBPROP:0000001 "A pharyngeal muscle is any muscle that forms part of the pharynx[GO]." xsd:string {date_retrieved="2012-06-30", external_class="GO:0043282", notes="does not quite work for some muscles such as stylopharyngeus", ontology="GO", source="GOC:go_curators"} property_value: UBPROP:0000202 FMA:67169 [Term] id: UBERON:0000945 name: stomach namespace: uberon def: "An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584, Wikipedia:Stomach] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior intestine" RELATED [] synonym: "gaster" RELATED [BTO:0001307] synonym: "mesenteron" RELATED [] synonym: "stomach chamber" NARROW [] synonym: "ventriculus" RELATED LATIN [Wikipedia:Stomach] xref: AAO:0000579 xref: ANISEED:1235297 xref: BTO:0001307 xref: CALOHA:TS-0980 xref: EFO:0000837 xref: EHDAA2:0001915 xref: EHDAA:2993 xref: EMAPA:17021 xref: EV:0100070 xref: FMA:7148 xref: GAID:293 xref: galen:Stomach xref: MA:0000353 xref: MAT:0000051 xref: MESH:D013270 xref: MIAA:0000051 xref: NCIT:C12391 xref: SCTID:181246003 xref: TAO:0002121 xref: UMLS:C0038351 {source="ncithesaurus:Stomach"} xref: VHOG:0000408 xref: Wikipedia:Stomach xref: XAO:0000128 is_a: UBERON:0004921 {source="cjm"} ! subdivision of digestive tract is_a: UBERON:0010039 {source="cjm"} ! food storage organ relationship: capable_of GO:0001696 {evidence="ISBN:0486692132"} ! gastric acid secretion relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system relationship: only_in_taxon NCBITaxon:7776 {notes="absent in lampreys and hagfishes", source="ISBN:0073040584"} ! Gnathostomata relationship: part_of UBERON:0001041 ! foregut property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/e/e0/Stomach_diagram.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:7864 {source="Wikipedia"} property_value: RO:0002161 NCBITaxon:7878 {source="Wikipedia"} property_value: RO:0002161 NCBITaxon:7955 {source="ZFA"} property_value: RO:0002161 NCBITaxon:9259 {source="Wikipedia"} property_value: UBPROP:0000001 "Portion of alimentary canal with increased circular and longitudinal smooth muscle. Bounded posteriorly by the pyloric sphincter. Mucosal lining has increased folding.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000579", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "It appears that the stomach has an ancient origin. The stomach first appears in the fish lineage. The prevertebrate chordates do not have a true stomach, whereas the cartilaginous and bony fish do. Although most fish do have a true stomach, some fish species appear to have lost the stomach secondarily. The remaining vertebrate lineages do have a true stomach (at least in the adult animal), although there is great variation in the size and shape of the stomach.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000408", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00076.x Smith DM, Grasty RC, Theodosiou NA, Tabin CJ, Nascone-Yoder NM, Evolutionary relationships between the amphibian, avian, and mammalian stomachs. Evolution and development (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "We restrict this to the vertebrate specific structure - see the grouping class 'food storage organ' for analogous structures in other species. Teleosts: Zebrafish is functionally stomach-less, but may retain ontogenic footprint. Although the precise shape and size of the stomach varies widely among different vertebrates, the relative positions of the oesophageal and duodenal openings remain relatively constant. As a result, the organ always curves somewhat to the left before curving back to meet the pyloric sphincter. However, lampreys, hagfishes, chimaeras, lungfishes, and some teleost fish have no stomach at all, with the oesophagus opening directly into the intestine. The gastric lining is usually divided into two regions, an anterior portion lined by fundic glands, and a posterior with pyloric glands. Cardiac glands are unique to mammals, and even then are absent in a number of species. The distributions of these glands vary between species, and do not always correspond with the same regions as in man. Furthermore, in many non-human mammals, a portion of the stomach anterior to the cardiac glands is lined with epithelium essentially identical to that of the oesophagus. Ruminants, in particular, have a complex stomach, the first three chambers of which are all lined with oesophageal mucosa" xsd:string {source="WP:Stomach#In_other_animals"} [Term] id: UBERON:0000947 name: aorta namespace: uberon def: "The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MESH:A07.231.114.056, MP:0000272, Wikipedia:Aorta] subset: efo_slim subset: grouping_class subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "arteria maxima" RELATED LATIN [Wikipedia:Aorta] synonym: "dorsal aorta" NARROW SENSU [Wikipedia:Aorta#In_other_animals, ZFA:0000014] synonym: "trunk of aortic tree" EXACT [] synonym: "trunk of systemic arterial tree" EXACT [] xref: AAO:0010213 xref: BTO:0000135 xref: CALOHA:TS-0046 xref: EFO:0000265 xref: EMAPA:18601 xref: EV:0100027 xref: FMA:3734 xref: GAID:469 xref: galen:Aorta xref: MA:0000062 xref: MAT:0000035 xref: MESH:D001011 xref: MIAA:0000035 xref: NCIT:C12669 xref: SCTID:181298001 xref: UMLS:C0003483 {source="ncithesaurus:Aorta"} xref: VHOG:0001523 xref: Wikipedia:Aorta xref: XAO:0003010 is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel is_a: UBERON:0003519 ! thoracic cavity blood vessel is_a: UBERON:0013768 ! great vessel of heart relationship: connected_to UBERON:0002084 ! heart left ventricle relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/91/Aorta_scheme.jpg" xsd:anyURI property_value: editor_note "This class is currently a mixed bag, encompassing (1) the entirety of the mammalian aorta together with (2) the developmental and phylogenetic homologs of its segments: the ventral aorta and dorsal aortae." xsd:string {source="WP"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The main artery of the circulatory system which carries oxygenated blood from the heart to all the arteries of the body except those of the lungs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010213", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001523", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "aortic" xsd:string property_value: UBPROP:0000008 "All amniotes have a broadly similar arrangement to that of humans, albeit with a number of individual variations. In fish, however, there are two separate vessels referred to as aortas. The ventral aorta carries de-oxygenated blood from the heart to the gills; part of this vessel forms the ascending aorta in tetrapods (the remainder forms the pulmonary artery). A second, dorsal aorta carries oxygenated blood from the gills to the rest of the body, and is homologous with the descending aorta of tetrapods. The two aortas are connected by a number of vessels, one passing through each of the gills. Amphibians also retain the fifth connecting vessel, so that the aorta has two parallel arches" xsd:string [Term] id: UBERON:0000948 name: heart namespace: uberon def: "A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heart] comment: Taxon notes:" the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)" DOI:10.1101/gad.1485706 subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "branchial heart" NARROW SENSU [] synonym: "cardium" RELATED [EMAPA:16105] synonym: "chambered heart" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "vertebrate heart" EXACT [] xref: AAO:0010210 xref: BILA:0000020 xref: BTO:0000562 xref: CALOHA:TS-0445 xref: EFO:0000815 xref: EHDAA2:0000738 xref: EHDAA:420 xref: EMAPA:16105 xref: EV:0100018 xref: FMA:7088 xref: GAID:174 xref: galen:Heart xref: MA:0000072 xref: MAT:0000036 xref: MESH:D006321 xref: MIAA:0000036 xref: NCIT:C12727 xref: SCTID:302509004 xref: TAO:0000114 xref: UMLS:C0018787 {source="ncithesaurus:Heart"} xref: VHOG:0000276 xref: Wikipedia:Heart xref: XAO:0000064 xref: ZFA:0000114 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0007100 ! primary circulatory organ is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0007100 ! primary circulatory organ intersection_of: has_part UBERON:0004151 ! cardiac chamber relationship: contributes_to_morphology_of UBERON:0004535 ! cardiovascular system relationship: develops_from UBERON:0004141 ! heart tube relationship: has_part UBERON:0004151 ! cardiac chamber relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0015410 {source="MA"} ! heart plus pericardium property_value: RO:0002161 NCBITaxon:6239 property_value: RO:0002161 NCBITaxon:7227 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000114", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010210", ontology="AAO"} property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000276", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "cardiac" xsd:string [Term] id: UBERON:0000949 name: endocrine system namespace: uberon def: "Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity." [NLM:endocrine+system, Wikipedia:Endocrine_system] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "endocrine glandular system" EXACT [EHDAA2:0002224] synonym: "endocrine system" EXACT [] synonym: "systema endocrinum" EXACT [] xref: AAO:0010279 xref: CALOHA:TS-1301 xref: EFO:0002969 xref: EHDAA2:0002224 xref: EMAPA:35306 xref: EV:0100128 xref: FBbt:00005068 xref: FMA:9668 xref: GAID:439 xref: MA:0000012 xref: MESH:D004703 xref: NCIT:C12705 xref: SCTID:278876000 xref: TAO:0001158 xref: UMLS:C0014136 {source="ncithesaurus:Endocrine_System"} xref: VHOG:0000098 xref: Wikipedia:Endocrine_system xref: XAO:0000158 xref: ZFA:0001158 is_a: UBERON:0015204 ! glandular system intersection_of: UBERON:0015203 ! non-connected functional system intersection_of: capable_of GO:0050886 ! endocrine process disjoint_from: UBERON:0000990 ! reproductive system disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0050886 ! endocrine process relationship: composed_primarily_of UBERON:0002368 ! endocrine gland relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000001 "Anatomical system containing glands which regulates bodily functions though the secretion of hormones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010279", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Multicellular organisms have complex endocrine systems, allowing responses to environmental stimuli, regulation of development, reproduction, and homeostasis. Nuclear receptors (NRs), a metazoan-specific family of ligand-activated transcription factors, play central roles in endocrine responses, as intermediates between signaling molecules and target genes. The NR family includes ligand-bound and orphan receptors, that is, receptors with no known ligand or for which there is no ligand Pocket. Understanding NR evolution has been further improved by comparison of several completed genomes, particularly those of deuterostomes and ecdysozoans. In contrast, evolution of NR ligands is still much debated. One hypothesis proposes that several independent gains and losses of ligand-binding ability in NRs occurred in protostomes and deuterostomes. A second hypothesis, pertaining to the NR3 subfamily (vertebrate steroid hormone receptors and estrogen related receptor), proposes that before the divergence of protostomes and deuterostomes, there was an ancestral steroid receptor (AncSR) that was ligand-activated and that orphan receptors secondarily lost the ability to bind a ligand. (...) Our analysis reveals that steroidogenesis has been independently elaborated in the 3 main bilaterian lineages (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000098", ontology="VHOG", source="DOI:10.1073/pnas.0812138106 Markov GV, Tavares R, Dauphin-Villemant C, Demeneix BA, Baker ME, Laudet V, Independent elaboration of steroid hormone signaling pathways in metazoans. PNAS (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "endocrine" xsd:string [Term] id: UBERON:0000951 name: rotator muscle of the vertebral column namespace: uberon def: "Any of a number of short transversospinal muscles chiefly developed in cervical, lumbar, and thoracic regions, arising from the transverse process of one vertebra and inserted into the root of the spinous process of the next two or three vertebrae above, with nerve supply from the dorsal branches of the spinal nerve, and whose actions rotate the vertebral column." [http://medical-dictionary.thefreedictionary.com/rotator+muscle] synonym: "rotator muscle" BROAD [FMA:23081] xref: FMA:23081 xref: SCTID:244872002 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001630 ! muscle organ is_a: UBERON:0005174 ! dorsal region element intersection_of: UBERON:0001630 ! muscle organ intersection_of: has_muscle_insertion UBERON:0001076 ! neural spine intersection_of: has_muscle_origin UBERON:0001077 ! transverse process of vertebra intersection_of: part_of UBERON:0001137 ! dorsum relationship: has_muscle_insertion UBERON:0001076 ! neural spine relationship: has_muscle_origin UBERON:0001077 ! transverse process of vertebra relationship: part_of RO:0002577 ! system [Term] id: UBERON:0000955 name: brain namespace: uberon def: "The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Brain] subset: cumbo subset: efo_slim subset: human_reference_atlas subset: major_organ subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "encephalon" RELATED [BTO:0000142] synonym: "suprasegmental levels of nervous system" RELATED [NeuroNames:21] synonym: "suprasegmental structures" RELATED [NeuroNames:21] synonym: "synganglion" RELATED [] synonym: "the brain" RELATED [NeuroNames:21] xref: AAO:0010478 xref: ABA:Brain xref: BAMS:Br xref: BAMS:Brain xref: BILA:0000135 xref: BIRNLEX:796 xref: BTO:0000142 xref: CALOHA:TS-0095 xref: DHBA:10155 xref: EFO:0000302 xref: EHDAA2:0000183 xref: EHDAA:2641 xref: EHDAA:6485 xref: EMAPA:16894 xref: EV:0100164 xref: FBbt:00005095 xref: FMA:50801 xref: GAID:571 xref: galen:Brain xref: HBA:4005 xref: MA:0000168 xref: MAT:0000098 xref: MBA:8 xref: MBA:997 xref: MESH:D001921 xref: MIAA:0000098 xref: NCIT:C12439 xref: neuronames:21 {source="BIRNLEX:796"} xref: PBA:3999 xref: SCTID:258335003 xref: TAO:0000008 xref: UMLS:C0006104 {source="ncithesaurus:Brain", source="BIRNLEX:796"} xref: UMLS:C1269537 {source="BIRNLEX:796"} xref: VHOG:0000157 xref: Wikipedia:Brain xref: XAO:0000010 xref: ZFA:0000008 is_a: UBERON:0000062 {source="GO"} ! organ is_a: UBERON:0004121 ! ectoderm-derived structure relationship: capable_of GO:0050890 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! cognition relationship: composed_primarily_of CL:0002319 ! neural cell relationship: contributes_to_morphology_of UBERON:0001016 ! nervous system relationship: develops_from UBERON:0001049 {gci_relation="part_of", gci_filler="NCBITaxon:7711"} ! neural tube relationship: develops_from UBERON:0006238 ! future brain relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: immediate_transformation_of UBERON:0006238 {source="Bgee:AN"} ! future brain relationship: in_anterior_side_of UBERON:0000468 ! multicellular organism relationship: part_of UBERON:0001017 {source="FMA"} ! central nervous system property_value: editor_note "requires review for applicability to invertebrate structures, e.g. synganglion" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000008", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of the central nervous system situated within the cranium and composed of both nerve cell bodies and nerve fibers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010478", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The part of the central nervous system contained within the cranium, comprising the forebrain, midbrain, hindbrain, and metencephalon. It is derived from the anterior part of the embryonic neural tube (or the encephalon). Does not include retina. (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000157", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000956 name: cerebral cortex namespace: uberon def: "The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex." [BIRNLEX:1494] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "brain cortex" RELATED [BTO:0000233] synonym: "cortex cerebralis" RELATED LATIN [NeuroNames:39] synonym: "cortex cerebri" RELATED LATIN [Wikipedia:Cerebral_cortex] synonym: "cortex of cerebral hemisphere" EXACT [BTO:0000233, FMA:61830] synonym: "cortical plate (areas)" RELATED [NeuroNames:39] synonym: "cortical plate (CTXpl)" RELATED [NeuroNames:39] synonym: "pallium of the brain" RELATED [BTO:0000233] xref: BAMS:C xref: BAMS:Cerebral_cortex xref: BAMS:CTX xref: BAMS:Cx xref: BIRNLEX:1494 xref: BM:Tel-Cx xref: BTO:0000233 xref: CALOHA:TS-0091 xref: DHBA:10159 xref: EFO:0000328 xref: EHDAA2:0000234 xref: EHDAA:5464 xref: EMAPA:17544 xref: EV:0100166 xref: FMA:61830 xref: GAID:629 xref: HBA:4008 xref: MA:0000185 xref: MAT:0000108 xref: MBA:688 xref: MESH:D002540 xref: MIAA:0000108 xref: NCIT:C12443 xref: neuronames:39 {source="BIRNLEX:1494"} xref: PBA:128011354 xref: SCTID:362880003 xref: UMLS:C0007776 {source="ncithesaurus:Cortex", source="BIRNLEX:1494"} xref: VHOG:0000722 xref: Wikipedia:Cerebral_cortex is_a: UBERON:0011215 ! central nervous system cell part cluster is_a: UBERON:0016548 {source="FMA"} ! central nervous system gray matter layer relationship: capable_of_part_of GO:0007613 {source="Wikipedia"} ! memory relationship: contributes_to_morphology_of UBERON:0001893 ! telencephalon relationship: has_developmental_contribution_from UBERON:0004035 ! cortical subplate relationship: has_developmental_contribution_from UBERON:0005343 ! cortical plate relationship: part_of UBERON:0000203 {source="GO", source="ISBN:0471888893"} ! pallium relationship: part_of UBERON:0005401 {source="FMA", source="MA"} ! cerebral hemisphere gray matter property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7b/Cerebral_Cortex_location.jpg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9a/Brainmaps-macaque-hippocampus.jpg" xsd:anyURI property_value: IAO:0000232 "We follow NIFSTD in defining cerebral cortex and including both neocortex and hippocampal formation (DG+hippocampus)." xsd:string property_value: RO:0002175 NCBITaxon:117569 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The cerebral cortex is a structure within the brain that plays a key role in memory, attention, perceptual awareness, thought, language, and consciousness. It constitutes the outermost layer of the cerebrum. In preserved brains, it has a grey color, hence the name 'grey matter'. Grey matter is formed by neurons and their unmyelinated fibers, whereas the white matter below the grey matter of the cortex is formed predominantly by myelinated axons interconnecting different regions of the central nervous system. The human cerebral cortex is 2-4 mm (0.08-0.16 inches) thick. The surface of the cerebral cortex is folded in large mammals, such that more than two-thirds of the cortical surface is buried in the grooves, called 'sulci. ' The phylogenetically most recent part of the cerebral cortex, the neocortex, also called isocortex, is differentiated into six horizontal layers; the more ancient part of the cerebral cortex, the hippocampus (also called archicortex), has at most three cellular layers, and is divided into subfields. Relative variations in thickness or cell type (among other parameters) allow us to distinguish between different neocortical architectonic fields. The geometry of at least some of these fields seems to be related to the anatomy of the cortical folds, and, for example, layers in the upper part of the cortical ridges seem to be more clearly differentiated than in its deeper parts. [WP,unvetted][Wikipedia:Cerebral_cortex]." xsd:string {source="Wikipedia:Cerebral_cortex"} property_value: UBPROP:0000003 "Migration of neurons from the basal or striatal portions of the anterior part of the neural tube occurs to varying degrees in different vertebrate classes, but a true cerebral cortex is generally acknowledged to have made its first appearance in reptiles. The definition can be unambiguous, since 'cortex' simply implies the existence of a surface neuronal layer with an overlying 'zonal lamina' or 'molecular' layer containing dendrites and axons, which is separated from the underlying basal 'matrix' by white matter. Although reptilian cerebral cortex does indeed fulfill these conditions in certain locations, the separation from striatal structures is often indistinct, so that it may even be argued that some primitive dipnoans possess a pallium or cortex. Nevertheless, an extensive laminated layer separated by underlying white matter is well represented only in reptiles and mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000722", ontology="VHOG", source="DOI:10.1111/j.1749-6632.1969.tb20437.x Kruger L, Experimental analyses of the reptilian nervous system. Annals of the New York Academy of Sciences (1969)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "hagfishes have independently evolved a highly laminated cerebral cortex, comparable in many ways to the cerebral cortex of mammals [http://icb.oxfordjournals.org/content/42/4/743]" xsd:string [Term] id: UBERON:0000957 name: lamina namespace: uberon def: "Any thin layer or plate." [Wikipedia:Lamina_of_the_vertebral_arch] subset: non_informative subset: uberon_slim subset: upper_level synonym: "laminar tissue" EXACT [] xref: Wikipedia:Lamina_of_the_vertebral_arch is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: has_quality PATO:0002124 ! laminar relationship: has_quality PATO:0002124 ! laminar property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/80/Laminaarcusvertebrae.png" xsd:anyURI property_value: editor_note "TODO - merge with cell layer?" xsd:string property_value: UBPROP:0000007 "laminar" xsd:string [Term] id: UBERON:0000962 name: nerve of cervical vertebra namespace: uberon def: "The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]." [Wikipedia:Cervical_nerves] comment: Innervates: sternohyoid muscle, sternothyroid muscle, omohyoid muscle[WP] subset: uberon_slim synonym: "cervical nerve" EXACT [FMA:5859] synonym: "cervical nerve tree" EXACT [] synonym: "cervical spinal nerve" EXACT [] synonym: "nervus cervicalis" EXACT LATIN [FMA:5859, FMA:TA] xref: BAMS:cern xref: FMA:5859 xref: NCIT:C32299 xref: neuronames:2351 xref: NLXANAT:20090207 xref: SCTID:360497008 xref: UMLS:C0228815 {source="ncithesaurus:Cervical_Nerve"} xref: Wikipedia:Cervical_nerves is_a: UBERON:0001780 ! spinal nerve intersection_of: UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0002726 ! cervical spinal cord relationship: extends_fibers_into UBERON:0002726 ! cervical spinal cord property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray795.png" xsd:anyURI [Term] id: UBERON:0000963 name: head sensillum namespace: uberon xref: FBbt:00004114 xref: MAT:0000204 xref: MIAA:0000204 is_a: UBERON:0002536 ! arthropod sensillum intersection_of: UBERON:0002536 ! arthropod sensillum intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head property_value: editor_note "this term should be ceded to the arthropod anatomy ontology" xsd:string [Term] id: UBERON:0000964 name: cornea namespace: uberon def: "The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure." [ISBN:0-683-40008-8, MESH:A09.371.060.217, MP:0001312] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cornea of camera-type eye" EXACT [GO:0061303] synonym: "corneas" RELATED PLURAL [ZFA:0000640] synonym: "tunica cornea" RELATED [] xref: AAO:0010344 xref: BTO:0000286 xref: CALOHA:TS-0171 xref: EFO:0000377 xref: EHDAA2:0000316 xref: EHDAA:10199 xref: EMAPA:17161 xref: EV:0100341 xref: FMA:58238 xref: GAID:892 xref: MA:0000266 xref: MESH:D003315 xref: NCIT:C12342 xref: SCTID:181162001 xref: TAO:0000640 xref: UMLS:C0010031 {source="ncithesaurus:Cornea"} xref: VHOG:0000164 xref: Wikipedia:Cornea xref: XAO:0000180 xref: ZFA:0000640 is_a: CARO:0000003 ! connected anatomical structure is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0010000 ! multicellular anatomical structure is_a: UBERON:0010313 ! neural crest-derived structure relationship: continuous_with UBERON:0001773 ! sclera relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball relationship: developmentally_induced_by UBERON:0005426 ! lens vesicle relationship: develops_from UBERON:0004348 {evidence="definitional"} ! optic eminence relationship: develops_from UBERON:0005427 ! corneal primordium relationship: has_part UBERON:0001772 ! corneal epithelium relationship: has_part UBERON:0004370 ! anterior limiting lamina of cornea relationship: has_quality PATO:0000964 ! transparent relationship: part_of UBERON:0001801 {source="MA"} ! anterior segment of eyeball relationship: part_of UBERON:0010409 {source="MA"} ! ocular surface region relationship: part_of UBERON:0012430 {source="FMA-isa"} ! tunica fibrosa of eyeball property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "corneal" xsd:string property_value: UBPROP:0000008 "Compared to terrestial animals, the cornea of zebrafish is relatively flat. It consists of nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman's membrane in mammals. In fish, and aquatic vertebrates in general, the cornea plays no role in focusing light, since it has virtually the same refractive index as water" xsd:string [Term] id: UBERON:0000965 name: lens of camera-type eye namespace: uberon def: "A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lens_(anatomy)] comment: The lens is avascular and nourished by diffusion from the aqueous and vitreous humors. subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "camera-type eye lens" EXACT [GO:0002088] synonym: "crystalline lens" RELATED [BTO:0000723, PMID:36055924] synonym: "eye lens" EXACT SENSU [] synonym: "lens" EXACT SENSU [] synonym: "lens crystallina" EXACT [Wikipedia:Lens_(anatomy)] synonym: "lenses" RELATED PLURAL [ZFA:0000035] synonym: "ocular lens" RELATED [BTO:0000723] xref: AAO:0010348 xref: BTO:0000723 xref: CALOHA:TS-0545 xref: EHDAA:9057 xref: EMAPA:17838 xref: EV:0100343 xref: FMA:58241 xref: MA:0000275 xref: MAT:0000141 xref: MESH:D007908 xref: MIAA:0000141 xref: NCIT:C12743 xref: RETIRED_EHDAA2:0000975 xref: SCTID:181169005 xref: TAO:0000035 xref: UMLS:C0023317 {source="ncithesaurus:Crystalline_Lens"} xref: VHOG:0000169 xref: Wikipedia:Lens_(anatomy) xref: XAO:0000008 xref: ZFA:0000035 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005389 ! transparent eye structure relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball relationship: developmentally_induced_by UBERON:0003902 ! retinal neural layer relationship: develops_from UBERON:0005426 ! lens vesicle relationship: part_of UBERON:0001801 ! anterior segment of eyeball property_value: RO:0002171 UBERON:0002049 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000169", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "This class excludes compound eye corneal lenses." xsd:string [Term] id: UBERON:0000966 name: retina namespace: uberon def: "The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." [Wikipedia:Retina, ZFIN:curator] comment: Currently this class encompasses only verteberate AOs but could in theory also include cephalopod - we may want to make a more specific class for vertebrate retina. note that this class excludes ommatidial retinas, as the retina must be part of an eyeball. Use the parent class photoreceptor array / light-sensitive tissue for arthropods subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "inner layer of eyeball" EXACT [] synonym: "Netzhaut" RELATED [BTO:0001175] synonym: "retina of camera-type eye" EXACT [GO:0060041] synonym: "retinas" RELATED PLURAL [ZFA:0000152] synonym: "tunica interna of eyeball" EXACT [] xref: AAO:0010352 xref: BAMS:R xref: BIRNLEX:1153 xref: BTO:0001175 xref: CALOHA:TS-0865 xref: EFO:0000832 xref: EHDAA2:0001627 xref: EHDAA:4757 xref: EMAPA:17168 xref: EV:0100348 xref: FMA:58301 xref: GAID:755 xref: MA:0000276 xref: MAT:0000142 xref: MBA:304325711 xref: MESH:D012160 xref: MIAA:0000142 xref: NCIT:C12343 xref: neuronames:1862 xref: NIFSTD_RETIRED:birnlex_1156 xref: SCTID:181171005 xref: TAO:0000152 xref: UMLS:C0035298 {source="BIRNLEX:1153", source="ncithesaurus:Retina"} xref: UMLS:C1278894 {source="BIRNLEX:1153"} xref: VHOG:0000229 xref: Wikipedia:Retina xref: XAO:0000009 xref: ZFA:0000152 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005388 ! photoreceptor array relationship: develops_from UBERON:0003072 {source="EHDAA2"} ! optic cup relationship: has_part CL:0000573 {source="FMA"} ! retinal cone cell relationship: has_part CL:0000604 {source="FMA"} ! retinal rod cell relationship: has_part CL:0000740 {source="FMA"} ! retinal ganglion cell relationship: part_of UBERON:0001802 ! posterior segment of eyeball relationship: part_of UBERON:0019207 ! chorioretinal region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ed/Human_eye_cross-sectional_view_grayscale.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:6656 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The portion of the eye developing from the optic primordium and including the neural retina and the retinal pigment layer. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000152", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000229", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "retinal" xsd:string [Term] id: UBERON:0000970 name: eye namespace: uberon def: "An organ that detects light." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: functional_classification subset: human_reference_atlas subset: major_organ subset: organ_slim subset: uberon_slim synonym: "light-detecting organ" RELATED [] synonym: "visual apparatus" RELATED [EV:0100336] xref: BILA:0000017 xref: BTO:0000439 xref: CALOHA:TS-0309 xref: EFO:0000827 xref: EV:0100336 xref: FBbt:00005162 xref: GAID:69 xref: MAT:0000140 xref: MESH:D005123 xref: MIAA:0000140 xref: Wikipedia:Eye is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000020 ! sense organ relationship: capable_of GO:0009584 ! detection of visible light relationship: has_part CL:0000149 {source="PMID:21062451"} ! visual pigment cell relationship: has_part CL:0000210 {source="PMID:21062451"} ! photoreceptor cell relationship: part_of UBERON:0002104 ! visual system property_value: IAO:0000232 "This class encompasses a variety of light-detecting structures from different phyla with no implication of homology, from the compound insect eye to the vertebrate camera-type eye (distinct classes are provided for each)" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "ocular" xsd:string property_value: UBPROP:0000007 "optic" xsd:string property_value: UBPROP:0000010 "Note that whilst this is classified as an organ, it is in fact more of a unit composed of different structures: in Drosophila, it includes the interommatidial bristle as a part; we consider here the vertebrate eye to include the eyeball/eye proper as a part, with the eye having as parts (when present): eyelids, conjuctiva," xsd:string [Term] id: UBERON:0000971 name: ommatidium namespace: uberon def: "The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells." [PMID:21062451] subset: uberon_slim synonym: "omatidia" RELATED PLURAL [] synonym: "omatidium" EXACT [] xref: BTO:0001922 xref: FBbt:00004510 xref: HAO:0000666 xref: MAT:0000143 xref: MIAA:0000143 xref: Wikipedia:Ommatidium is_a: UBERON:0000970 {source="PMID:21062451"} ! eye is_a: UBERON:0002536 ! arthropod sensillum relationship: part_of UBERON:0000018 ! compound eye property_value: UBPROP:0000007 "ommatidial" xsd:string [Term] id: UBERON:0000974 name: neck namespace: uberon def: "An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "collum" RELATED LATIN [Wikipedia:Neck] synonym: "neck (volume)" RELATED [FMA:7155] xref: AEO:0000108 xref: BTO:0000420 xref: CALOHA:TS-2045 xref: EFO:0000967 xref: EHDAA2:0003108 xref: EMAPA:35587 xref: FMA:7155 xref: GAID:86 xref: galen:Neck xref: MA:0000024 xref: MAT:0000297 xref: MESH:D009333 xref: MIAA:0000297 xref: NCIT:C13063 xref: SCTID:302550007 xref: UMLS:C0027530 {source="ncithesaurus:Neck"} xref: Wikipedia:Neck is_a: UBERON:0000475 ! organism subdivision relationship: anteriorly_connected_to UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:8287 ! Sarcopterygii relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0007811 ! craniocervical region relationship: posteriorly_connected_to UBERON:0002100 ! trunk property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/99/Female_neck.jpg" xsd:anyURI property_value: IAO:0000232 "true necks are considered to be present when the pectoral girdle is separate from the skull - Tiktaalik is the earliest known fish to have a true neck." xsd:string property_value: RO:0002174 NCBITaxon:32443 {source="ISBN:9780674021839"} property_value: UBPROP:0000007 "cervical" xsd:string [Term] id: UBERON:0000975 name: sternum namespace: uberon def: "A midventral endochondral skeletal element which represents the origin site of the pectoral muscles[PHENOSCAPE:ad]." [https://github.com/obophenotype/uberon/issues/67, PHENOSCAPE:ad] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "breastbone" RELATED [BTO:0001302] synonym: "vertebrate sternum" EXACT [] xref: AAO:0000765 xref: BTO:0001302 xref: CALOHA:TS-0972 xref: EHDAA2:0001914 xref: EHDAA:9561 xref: EMAPA:18344 xref: FMA:7485 xref: GAID:246 xref: galen:Sternum xref: MA:0001331 xref: MESH:D013249 xref: NCIT:C12793 xref: SCTID:302522007 xref: UMLS:C0038293 {source="ncithesaurus:Sternum"} xref: VHOG:0000856 xref: Wikipedia:Sternum is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0010363 {source="ISBN:0073040584"} ! endochondral element relationship: connected_to UBERON:0002228 ! rib relationship: connected_to UBERON:0007831 ! pectoral girdle skeleton relationship: connected_to UBERON:0008255 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! right clavicle relationship: connected_to UBERON:0008256 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! left clavicle relationship: contributes_to_morphology_of UBERON:0003252 ! thoracic rib cage relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: only_in_taxon NCBITaxon:32523 {source="ISBN:0073040584"} ! Tetrapoda relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0003252 {source="FMA"} ! thoracic rib cage property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/12/Illu_thoracic_cage.jpg" xsd:anyURI property_value: editor_note "in EMAPA and EHDAA2 this is part of the skeleton of pectoral girdle; the classic def of pectoral girdle (see WP) excludes the rib cage and sternum" xsd:string property_value: RO:0002161 NCBITaxon:8570 {source="Wikipedia"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Single element that constitutes the postzonal area of the pectoral girdle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000765", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: part_of postzonal element (AAO:0000938)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000765", ontology="AAO"} property_value: UBPROP:0000003 "Fishes lack a sternum. (...) A sternum is absent in the first fossil tetrapods, but it is present in modern amphibians. (...) Thus, a sternum occurs in some modern amphibians, birds, mammals and archosaurs. However, its absence in the common ancestors to these groups means that it has arisen independently several times within the field of the midventral connective tissue.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000856", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.294", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "sternal" xsd:string property_value: UBPROP:0000008 "in birds, either ratite (no keel or carina) or carinate (keel and carina present)" xsd:string property_value: UBPROP:0000008 "It probably first evolved in early tetrapods as an extension of the pectoral girdle; it is not found in fish. In amphibians and reptiles it is typically a shield-shaped structure, often composed entirely of cartilage. It is absent in both turtles and snakes. In birds it is a relatively large bone and typically bears an enormous projecting keel to which the flight muscles are attached. Only in mammals does the sternum take on the elongated, segmented form seen in humans. In some mammals, such as opossums, the individual segments never fuse and remain separated by cartilagenous plates throughout life" xsd:string property_value: UBPROP:0000011 "While its developmental origins are similar to the ribs (from the myospetum and septum of the trunk region), it is often associated with the pectoral skeleton, due to both function and physical connections (i.e. the coracoid of archosaurs). It may be a single element or a series of smaller structure (sternebrae). Based on Kardong 2012. [PHENOSCAPE:ad]." xsd:string {source="WP"} [Term] id: UBERON:0000976 name: humerus namespace: uberon def: "Paired endochondral long bone that extends between the pectoral girdle and the skeletal parts of the forelimb. [PHENOSCAPE:mah]." [AAO:0000679, https://github.com/obophenotype/uberon/issues/106, PHENOSCAPE:mah] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "humeri" EXACT PLURAL [PHENOSCAPE:ad] synonym: "humerus bone" EXACT [] synonym: "mesomere 1 of pectoral appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "proximal metapterygial mesomere of pectoral appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "proximal metapterygial mesomere of pectoral fin" RELATED HOMOLOGY [ISBN:0226313409] xref: AAO:0000679 xref: CALOHA:TS-2202 xref: EFO:0001398 xref: EMAPA:19106 xref: FMA:13303 xref: GAID:183 xref: galen:Humerus xref: MA:0001356 xref: MESH:D006811 xref: NCIT:C12731 xref: SCTID:181923006 xref: UMLS:C0020164 {source="ncithesaurus:Humerus"} xref: VHOG:0001158 xref: Wikipedia:Humerus xref: XAO:0003210 is_a: UBERON:0003461 ! shoulder bone is_a: UBERON:0003607 ! forelimb long bone is_a: UBERON:0004250 ! upper arm bone is_a: UBERON:0015053 ! humerus endochondral element intersection_of: UBERON:0015053 ! humerus endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0006245 {evidence="definitional"} ! humerus cartilage element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: overlaps UBERON:0001470 ! glenohumeral joint relationship: proximally_connected_to UBERON:0007831 ! pectoral girdle skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/67/Illu_upper_extremity.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Paired, elongate, cylindrical bones of endochondral origin that extend from the pectoral girdle to the elbows.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000679", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001158", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "humeral" xsd:string [Term] id: UBERON:0000977 name: pleura namespace: uberon def: "The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion)." [https://github.com/obophenotype/uberon/issues/1231, ISBN:0-683-40008-8, MP:0010820, UBERON:cjm, Wikipedia:Pulmonary_pleurae] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "pleura" RELATED [] synonym: "pleural tissue" RELATED [BTO:0001791, NCIT:C12469] synonym: "wall of pleural sac" EXACT [] xref: BTO:0001791 xref: CALOHA:TS-2081 xref: EFO:0001980 xref: EMAPA:16775 xref: EV:0100044 xref: FMA:9583 xref: GAID:360 xref: MA:0000433 xref: MESH:D010994 xref: NCIT:C12469 xref: SCTID:181609007 xref: UMLS:C0032225 {source="ncithesaurus:Pleural_Tissue"} xref: VHOG:0000394 xref: Wikipedia:Pleura is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: has_part UBERON:0002400 ! parietal pleura intersection_of: has_part UBERON:0002401 ! visceral pleura intersection_of: part_of UBERON:0009778 ! pleural sac relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system relationship: develops_from UBERON:0003081 ! lateral plate mesoderm relationship: has_part UBERON:0002400 ! parietal pleura relationship: has_part UBERON:0002401 ! visceral pleura relationship: has_quality PATO:0001748 ! invaginated relationship: only_in_taxon NCBITaxon:32524 ! Amniota relationship: part_of UBERON:0009778 {source="https://github.com/obophenotype/uberon/issues/86"} ! pleural sac property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:8782 {source="ISBN:978-0030223693", source="https://orcid.org/0000-0003-3308-6245"} property_value: UBPROP:0000001 "The serous membrane that covers the lungs and lines the pleural cavity. [Kaufman_MH_and_Bard_JBL, The_anatomical_basis_of_mouse_development_(1999)_San_Diego:_Academic_Press, p.264][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000394", ontology="VHOG", source="ISBN:0124020607", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "pleural" xsd:string property_value: UBPROP:0000012 "In MA, is_a cavity lining (which we equate to parietal). In FMA, is_a (viscous) serous membrane (which includes mesothelium plus connective tissue). Note the MA structure should probably be associated with the mesothelium of pleura in FMA. JB/EHDAA2 argues the term 'pleura' is best used for the mesothelial lining (thus excluding connective tissue). See https://github.com/obophenotype/uberon/issues/86" xsd:string [Term] id: UBERON:0000978 name: leg namespace: uberon def: "The portion of the hindlimb that contains both the stylopod and zeugopod." [Wikipedia:Leg#Limb] comment: we use the less open to misinterpretation 'hindlimb zeugopod'. Editor note: currently declared as overlapping foot, as AOs disagree over whether some ankle parts are in the leg or foot subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "lower extremity" RELATED [MESH:A01.378.610] synonym: "tetrapod leg" EXACT [] xref: BTO:0000721 xref: CALOHA:TS-2206 xref: EFO:0001411 xref: EHDAA2:0000972 xref: EHDAA:5151 xref: EHDAA:6176 xref: EHDAA:8289 xref: EMAPA:17489 xref: GAID:49 xref: MA:0000047 xref: MESH:D035002 xref: VHOG:0000345 xref: Wikipedia:Leg#Limb is_a: UBERON:0006058 ! multi-limb segment region is_a: UBERON:0008784 ! lower limb segment relationship: distally_connected_to UBERON:0002387 ! pes relationship: proximally_connected_to UBERON:0001464 ! hip property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000345", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "The term leg can mean: [1] an appendage on which an animal walks [2] the entire hindlimb of a tetrapod [3] the segment of a human leg between knee and ankle (cf FMA) [4] the region of a hindlimb include the stylopod and zeugopod, but excluding the autopod. We define this class as [4], and thus 'leg' is compltely analagous to 'arm'. For [1], see the class 'locomotive weight-bearing appendage'. For [2] we use 'hindlimb'. For" xsd:string {source="3"} [Term] id: UBERON:0000979 name: tibia namespace: uberon def: "The major preaxial endochondral bone in the posterior zeugopod[Phenoscape]." [PHENOSCAPE:mah] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "shankbone" EXACT [Wikipedia:Tibia] synonym: "shinbone" EXACT [Wikipedia:Tibia] xref: AAO:0000890 xref: BTO:0001252 xref: CALOHA:TS-1048 xref: EFO:0003054 xref: EMAPA:19142 xref: FMA:24476 xref: GAID:204 xref: galen:Tibia xref: MA:0001361 xref: MESH:D013977 xref: NCIT:C12800 xref: SCTID:182061009 xref: UMLS:C0040184 {source="ncithesaurus:Tibia"} xref: Wikipedia:Tibia is_a: UBERON:0003608 ! hindlimb long bone is_a: UBERON:0004251 ! hindlimb zeugopod bone is_a: UBERON:0015004 ! tibia endochondral element intersection_of: UBERON:0015004 ! tibia endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010849 ! tibia cartilage element relationship: preaxialmost_part_of UBERON:0010720 ! hindlimb zeugopod skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2a/Gray260.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of the two long bones of endochondral origin of the hind-epipodium; it is a straight, simple bone whose section is more or less rectangular at the ends and circular at its central portion.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000890", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0000980 name: trochanter namespace: uberon def: "A bony prominence near the extremity of the femur that normally serves as attachment points for hip and thigh muscles[MP,modified]." [MP:0004627] subset: pheno_slim subset: uberon_slim synonym: "femoral trochanter" EXACT [AAO:0000897] synonym: "trochanter of femur" EXACT [] xref: AAO:0000897 xref: FMA:82513 xref: MA:0002821 xref: NCIT:C33814 xref: SCTID:182047004 xref: UMLS:C0162370 {source="ncithesaurus:Trochanter"} xref: Wikipedia:Trochanter is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: contributes_to_morphology_of UBERON:0000981 ! femur relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000981 {source="MA"} ! femur property_value: UBPROP:0000001 "Process on the ventral surface of the shaft of the femur.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000897", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000008 "there are two in human (greater and lesser trochanters) and three in many other mammalian species (greater, lesser and third)" xsd:string {source="MP"} [Term] id: UBERON:0000981 name: femur namespace: uberon def: "Endochondral longbone connecting the pelvic girdle with posterior zeugopodium skeleton.[VSAO, modified]." [VSAO:0000186, Wikipedia:Femur] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "femoral bone" RELATED [BTO:0001284] synonym: "mesomere 1 of pevlic appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "os femorale" RELATED LATIN [BTO:0001284] synonym: "os femoris" RELATED LATIN [BTO:0001284] synonym: "os longissimum" RELATED LATIN [Wikipedia:Femur] synonym: "proximal metapterygial mesomere of pelvic appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "proximal metapterygial mesomere of pelvic fin" RELATED HOMOLOGY [ISBN:0226313409] synonym: "thigh bone" EXACT [] xref: AAO:0000887 xref: AAO:0000889 xref: BTO:0001284 xref: CALOHA:TS-0322 xref: EFO:0001396 xref: EMAPA:19143 xref: FMA:9611 xref: GAID:199 xref: galen:Femur xref: MA:0001359 xref: MESH:D005269 xref: NCIT:C12717 xref: SCTID:182046008 xref: UMLS:C0015811 {source="ncithesaurus:Femur"} xref: VHOG:0001159 xref: VSAO:0000186 xref: Wikipedia:Femur xref: XAO:0003214 is_a: UBERON:0003608 ! hindlimb long bone is_a: UBERON:0003826 ! upper leg bone is_a: UBERON:0008202 {source="MA"} ! bone of hip region is_a: UBERON:0015052 ! femur endochondral element intersection_of: UBERON:0015052 ! femur endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: connected_to UBERON:0000979 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tibia relationship: connected_to UBERON:0001272 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! innominate bone relationship: connected_to UBERON:0002446 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! patella relationship: develops_from UBERON:0010129 {evidence="definitional"} ! femur cartilage element relationship: proximally_connected_to UBERON:0007832 ! pelvic girdle skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/73/Gray252.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Endochondral longbone connecting the pelvic girdle with posterior zeugopodium.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000186", ontology="VSAO", source="VSAO:NI"} property_value: UBPROP:0000001 "Paired, elongate, cylindrical bones of endochondral origin that form the thighs, extending from the pelvic girdles to the knees.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000889", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001159", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "femoral" xsd:string [Term] id: UBERON:0000982 name: skeletal joint namespace: uberon def: "Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000101, Wikipedia:Joint] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "articular joint" RELATED [BTO:0001686] synonym: "articulation" BROAD [VSAO:0000101] synonym: "joint" BROAD [FMA:7490, VSAO:0000101] synonym: "joints" RELATED PLURAL [ZFA:0001596] xref: AEO:0000182 xref: BTO:0001686 xref: CALOHA:TS-2023 xref: EFO:0000948 xref: EMAPA:35456 xref: FMA:7490 xref: GAID:102 xref: galen:Joint xref: MA:0000319 xref: MAT:0000188 xref: MESH:D007596 xref: MIAA:0000188 xref: NCIT:C13044 xref: RETIRED_EHDAA2:0003182 xref: SCTID:302536002 xref: TAO:0000367 xref: UMLS:C0022417 {source="ncithesaurus:Joint"} xref: VHOG:0001276 xref: VSAO:0000101 xref: Wikipedia:Joint xref: XAO:0000171 xref: ZFA:0001596 is_a: UBERON:0004905 ! articulation union_of: UBERON:0002217 ! synovial joint union_of: UBERON:0011134 ! nonsynovial joint disjoint_from: UBERON:0001474 ! bone element relationship: connects UBERON:0004765 ! skeletal element relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system property_value: UBPROP:0000001 "Anatomical cluster that consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000101", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Anatomical cluster which consists of two or more adjacent bones or cartilages, which may be interconnected by various types of tissue.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000367", ontology="TAO", source="TAO:pem"} [Term] id: UBERON:0000983 name: metatarsus region namespace: uberon def: "A metapodium region that is part of a pes." [OBOL:automatic] subset: uberon_slim synonym: "hind metapodium" EXACT [AAO:0000221, http://en.wiktionary.org/wiki/metapodial, MA:th] synonym: "hindlimb cannon region" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "hindlimb equine cannon region" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "metatarsal part of foot" EXACT [FMA:24997] synonym: "metatarsal region" EXACT [FMA:24997] synonym: "metatarsus" RELATED [MA:0000049] synonym: "regio metatarsalis" EXACT LATIN [FMA:24997, FMA:TA] xref: CALOHA:TS-2221 xref: FMA:24997 xref: MA:0000049 xref: SCTID:280711000 xref: SCTID:370639003 is_a: UBERON:0008784 ! lower limb segment is_a: UBERON:0009877 ! metapodium region intersection_of: UBERON:0009877 ! metapodium region intersection_of: part_of UBERON:0002387 ! pes relationship: has_skeleton UBERON:0010545 ! metatarsus skeleton relationship: part_of UBERON:0012142 {source="PHENOSCAPE:ni"} ! pedal digitopodium region property_value: UBPROP:0000012 "mammalian and non-mammalian AOs differ in whether they consider this a part of the skeleton" xsd:string [Term] id: UBERON:0000985 name: axillary vein namespace: uberon def: "Vein that drains the axilla." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim synonym: "subcostal vein" RELATED [] synonym: "vena axillaris" EXACT LATIN [Wikipedia:Axillary_vein] xref: EMAPA:18758 xref: FMA:13329 xref: GAID:527 xref: galen:AxillaryVein xref: MA:0002084 xref: MESH:D001367 xref: NCIT:C32171 xref: SCTID:181389002 xref: UMLS:C0004456 {source="ncithesaurus:Axillary_Vein"} xref: Wikipedia:Axillary_vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0009472 ! axilla relationship: connected_to UBERON:0001587 ! subclavian vein relationship: drains UBERON:0009472 ! axilla relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001467 ! shoulder property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray576.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In human anatomy, the axillary vein is a large blood vessel that conveys blood from the lateral aspect of the thorax, axilla (armpit) and upper limb toward the heart. There is one axillary vein on each side of the body. Its origin is at the lower margin of the teres major muscle and a continuation of the brachial vein. Its tributaries include the basilic vein and cephalic vein, which are both superficial veins. It terminates at the lateral margin of the first rib, at which it becomes the subclavian vein. It is accompanied along its course by a similarly named artery, the axillary artery" xsd:string {source="WP"} [Term] id: UBERON:0000988 name: pons namespace: uberon def: "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum." [VHOG:0001176] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "pons cerebri" RELATED LATIN [NeuroNames:547] synonym: "pons of Varolius" EXACT [] synonym: "pons Varolii" EXACT [ncithesaurus:Pons_Varolii] xref: BAMS:PONS xref: BAMS:Pons xref: BIRNLEX:733 xref: BM:Pons xref: BTO:0001101 xref: CALOHA:TS-0813 xref: DHBA:10661 xref: EFO:0001394 xref: EHDAA2:0004394 xref: EMAPA:17563 xref: EV:0100253 xref: FMA:67943 xref: GAID:578 xref: HBA:9131 xref: MA:0000204 xref: MAT:0000115 xref: MBA:771 xref: MESH:D011149 xref: MIAA:0000115 xref: NCIT:C12511 xref: neuronames:547 {source="BIRNLEX:733"} xref: SCTID:279103004 xref: UMLS:C0032639 {source="BIRNLEX:733", source="ncithesaurus:Pons_Varolii"} xref: UMLS:C1280999 {source="BIRNLEX:733"} xref: VHOG:0001176 xref: Wikipedia:Pons is_a: UBERON:0002616 ! regional part of brain relationship: contributes_to_morphology_of UBERON:0001895 ! metencephalon relationship: contributes_to_morphology_of UBERON:0002298 ! brainstem relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001895 {source="neuronames"} ! metencephalon relationship: part_of UBERON:0002298 ! brainstem property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/36/Gray768.png" xsd:anyURI property_value: editor_note "The pons is not present in zebrafish. In this ontology we currently have some structures which are applicable to zebrafish appearing as parts of the pons. Currently we only include the weaker dubious_for_taxon relationship ubtil this is resolved" xsd:string property_value: RO:0002174 NCBITaxon:7955 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001176", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pons"} property_value: UBPROP:0000003 "During the embryonic development of birds and mammals, neuroblasts migrate from the cerebellum into the ventral part of the rhombencephalon and differentiate into pontine and other nuclei, which relay information from between the cerebrum and cerebellum, and a conspicuous band of transverse fibers. This region is known as the pons. A pons does not differentiate in reptiles and anamniotes (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001176", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.474", source="http://bgee.unil.ch/"} [Term] id: UBERON:0000989 name: penis namespace: uberon def: "An intromittent organ in certain biologically male organisms. In placental mammals, this also serves as the organ of urination." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0005187, Wikipedia:Penis] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "penes" RELATED PLURAL [] synonym: "phallus" RELATED [] xref: BTO:0000405 xref: CALOHA:TS-0758 xref: EFO:0000987 xref: EHDAA2:0001433 xref: EHDAA:9380 xref: EMAPA:18682 xref: EMAPA_RETIRED:18996 xref: EV:0100107 xref: FMA:9707 xref: GAID:389 xref: galen:Penis xref: MA:0000408 xref: MAT:0000186 xref: MESH:D010413 xref: MIAA:0000186 xref: NCIT:C12409 xref: SCTID:265793009 xref: UMLS:C0030851 {source="ncithesaurus:Penis"} xref: VHOG:0000727 xref: Wikipedia:Penis is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0008811 {source="Wikipedia"} ! intromittent organ relationship: develops_from UBERON:0004876 {source="Wikipedia"} ! urogenital fold relationship: develops_from UBERON:0005876 {source="EHDAA2"} ! undifferentiated genital tubercle property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/87/Labelled_flaccid_penis.jpg" xsd:anyURI property_value: UBPROP:0000007 "penile" xsd:string property_value: UBPROP:0000007 "phallic" xsd:string property_value: UBPROP:0000008 "Most male birds (e.g., roosters and turkeys) have a cloaca (also present on the female), but not a penis. Among bird species with a penis are paleognathes (tinamous and ratites), Anatidae (ducks, geese and swans), and a very few other species (such as flamingoes). A bird penis is different in structure from mammal penises, being an erectile expansion of the cloacal wall and being erected by lymph, not blood. It is usually partially feathered and in some species features spines and brush-like filaments, and in flaccid state curls up inside the cloaca" xsd:string {source="WP"} [Term] id: UBERON:0000990 name: reproductive system namespace: uberon def: "Anatomical system that has as its parts the organs concerned with reproduction." [Wikipedia:Reproductive_system] subset: efo_slim subset: functional_classification subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "animal reproductive system" RELATED [BTO:0000081] synonym: "genital system" NARROW [] synonym: "genital tract" RELATED [] synonym: "genitalia" NARROW PLURAL [] synonym: "Geschlechtsorgan" RELATED [BTO:0000081] synonym: "organa genitalia" RELATED [BTO:0000081] synonym: "reproductive tissue" RELATED [BTO:0000081] synonym: "reproductive tract" RELATED [] synonym: "systemata genitalia" RELATED LATIN [Wikipedia:Reproductive_system] xref: AAO:0010258 xref: BILA:0000103 xref: BTO:0000081 xref: CALOHA:TS-1318 xref: EFO:0000809 xref: EHDAA2:0001603 xref: EHDAA:5923 xref: EMAPA:17381 xref: EV:0100100 xref: FBbt:00004857 xref: FMA:7160 xref: GAID:363 xref: HAO:0000374 xref: HAO:0000895 xref: MA:0000326 xref: MIAA:0000305 xref: NCIT:C12841 xref: SCTID:278875001 xref: TAO:0000632 xref: UMLS:C1261210 {source="ncithesaurus:Reproductive_System"} xref: VHOG:0000182 xref: WBbt:0005747 xref: Wikipedia:Reproductive_system xref: XAO:0000142 xref: ZFA:0000632 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of_part_of GO:0000003 ! reproduction disjoint_from: UBERON:0001004 ! respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of_part_of GO:0000003 ! reproduction relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000991 ! gonad property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/52/Penis.svg" xsd:anyURI property_value: editor_note "consider splitting genitalia from reproductive system" xsd:string property_value: http://purl.org/dc/terms/date "2022-06-10T18:22:34Z" xsd:dateTime property_value: UBPROP:0000001 "Anatomical system which consists of organs and tissues associated with sexual reproduction of the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010258", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Arguably, one of the most important aspects of urbilaterian organogenesis would have been gonadogenesis, since Urbilateria must have successfully generated gametes and developed a strategy for extrusion and fertilization, in order to be the ancestor of all living Bilateria.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000182", ontology="VHOG", source="PMID:21672850 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across Bilateria. Integrative and Comparative Biology (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000202 FMA:75572 [Term] id: UBERON:0000991 name: gonad namespace: uberon def: "Reproductive organ that produces and releases eggs (ovary) or sperm (testis)." [ISBN:0140512888, Wikipedia:Gonad, ZFA:0000413, ZFIN:curator] subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gonada" EXACT [] synonym: "gonads" RELATED PLURAL [ZFA:0000413] xref: AAO:0000213 xref: BILA:0000123 xref: BSA:0000079 xref: BTO:0000534 xref: EMAPA:17383 xref: FBbt:00004858 xref: FMA:18250 xref: GAID:368 xref: HAO:0000379 xref: MA:0002420 xref: MESH:D006066 xref: NCIT:C12725 xref: SCTID:304623008 xref: TAO:0000413 xref: UMLS:C0018067 {source="ncithesaurus:Gonad"} xref: VHOG:0000397 xref: WBbt:0005175 xref: Wikipedia:Gonad xref: XAO:0003146 xref: ZFA:0000413 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: has_part CL:0000586 ! germ cell relationship: contains_process GO:0007276 ! gamete generation relationship: develops_from UBERON:0005564 ! gonad primordium relationship: has_part CL:0000586 ! germ cell property_value: UBPROP:0000001 "Anatomical structure which produces gametes as well as certain sex hormones controlled by the pituitary gonadotropins.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000213", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The part of the reproductive system that produces and releases eggs (ovary) or sperm (testis).[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000413", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000397", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T, Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "gonadal" xsd:string property_value: UBPROP:0000012 "FMA xref is a 'general anatomical term'" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0000992 name: ovary namespace: uberon def: "The gonad of a female organism which contains germ cells." [ISBN:0-683-40008-8, MP:0001126, Wikipedia:Ovary] subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "animal ovary" EXACT [EFO:0000973] synonym: "female gonad" EXACT [] synonym: "female organism genitalia gonad" EXACT [OBOL:automatic] synonym: "female organism genitalia gonada" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonad" EXACT [OBOL:automatic] synonym: "female organism reproductive system gonada" EXACT [OBOL:automatic] synonym: "female reproductive system gonad" EXACT [OBOL:automatic] synonym: "female reproductive system gonada" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonad" EXACT [OBOL:automatic] synonym: "genitalia of female organism gonada" EXACT [OBOL:automatic] synonym: "gonad of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonad of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "gonad of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonad of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "gonada of female organism genitalia" EXACT [OBOL:automatic] synonym: "gonada of female organism reproductive system" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "gonada of genitalia of female organism" EXACT [OBOL:automatic] synonym: "gonada of reproductive system of female organism" EXACT [OBOL:automatic] synonym: "ovaries" RELATED PLURAL [] synonym: "ovarium" RELATED LATIN [Wikipedia:Ovary] synonym: "ovum-producing ovary" EXACT SENSU [GO:0061039] synonym: "reproductive system of female organism gonad" EXACT [OBOL:automatic] synonym: "reproductive system of female organism gonada" EXACT [OBOL:automatic] xref: AAO:0000371 xref: BILA:0000125 xref: BSA:0000080 xref: BTO:0000975 xref: CALOHA:TS-0730 xref: EFO:0000973 xref: EHDAA2:0001360 xref: EHDAA:8124 xref: EMAPA:17962 xref: EV:0100111 xref: FBbt:00004865 xref: FMA:7209 xref: GAID:367 xref: MA:0000384 xref: MESH:D010053 xref: MIAA:0000125 xref: NCIT:C12404 xref: SCTID:181464007 xref: TAO:0000403 xref: UMLS:C0029939 {source="ncithesaurus:Ovary"} xref: VHOG:0000251 xref: Wikipedia:Ovary xref: XAO:0000258 xref: ZFA:0000403 is_a: UBERON:0000991 ! gonad is_a: UBERON:0003134 ! female reproductive organ intersection_of: UBERON:0000991 ! gonad intersection_of: part_of UBERON:0000474 ! female reproductive system disjoint_from: UBERON:0009117 ! indifferent gonad relationship: develops_from UBERON:0009117 ! indifferent gonad relationship: in_lateral_side_of UBERON:0003975 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA-abduced-lr"} ! internal female genitalia relationship: only_in_taxon NCBITaxon:33208 ! Metazoa property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray589.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Either of paired female reproductive organs involved in production of ova and female sex hormones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000371", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Female reproductive organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000403", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "(...) while it is likely that Urbilateria lacked a complex somatic reproductive system, it is at present impossible to speculate on whether or not it possessed a true gonad, let alone any other somatic adaptations for reproduction (reference 1); Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved (reference 2).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000251", ontology="VHOG", source="DOI:10.1093/icb/icm052 Extavour CGM, Gray anatomy: phylogenetic patterns of somatic gonad structures and reproductive strategies across the Bilateria. Integrative and Comparative Biology (2007), DOI:10.1146/annurev.cellbio.042308.13350 DeFalco T and Capel B, Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annual review of cell and developmental biology (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ovarian" xsd:string property_value: UBPROP:0000008 "Ovaries of some kind are found in the female reproductive system of many animals that employ sexual reproduction, including invertebrates. However, they develop in a very different way in most invertebrates than they do in vertebrates, and are not truly homologous. Many of the features found in human ovaries are common to all vertebrates, including the presence of follicular cells, tunica albuginea, and so on. However, many species produce a far greater number of eggs during their lifetime than do humans, so that, in fish and amphibians, there may be hundreds, or even millions of fertile eggs present in the ovary at any given time. In these species, fresh eggs may be developing from the germinal epithelium throughout life. Corpora lutea are found only in mammals, and in some elasmobranch fish; in other species, the remnants of the follicle are quickly resorbed by the ovary. In birds, reptiles, and monotremes, the egg is relatively large, filling the follicle, and distorting the shape of the ovary at maturity. Amphibians and reptiles have no ovarian medulla; the central part of the ovary is a hollow, lymph-filled space. The ovary of teleosts is also often hollow, but in this case, the eggs are shed into the cavity, which opens into the oviduct. Although most normal female vertebrates have two ovaries, this is not the case in all species. In birds and platypuses, the right ovary never matures, so that only the left is functional. In some elasmobranchs, the reverse is true, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo" xsd:string {source="WP"} [Term] id: UBERON:0000993 name: oviduct namespace: uberon def: "A tube or collection of tubes in an animal from the ovaries to the outside of the body." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: uberon_slim subset: vertebrate_core synonym: "female reproductive tracts" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "ovarian duct" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ovarian tube" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "oviducts" RELATED PLURAL [ZFA:0000560] synonym: "tuba uterina" RELATED [BTO:0000980] synonym: "tuba uterinae" RELATED [BTO:0000980] synonym: "tubular parts of female reproductive system" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "uterine tube" EXACT [] xref: AAO:0010533 xref: BSA:0000083 xref: BTO:0000980 xref: EFO:0000974 xref: EMAPA:18984 xref: GAID:366 xref: MAT:0000126 xref: MESH:D010057 xref: MIAA:0000126 xref: NCIT:C77957 xref: TAO:0000560 xref: UMLS:C0029954 {source="ncithesaurus:Oviduct"} xref: VHOG:0001136 xref: Wikipedia:Oviduct xref: XAO:0003052 xref: ZFA:0000560 is_a: UBERON:0000025 ! tube is_a: UBERON:0005156 ! reproductive structure relationship: connects UBERON:0000992 ! ovary relationship: connects UBERON:0013514 ! space surrounding organism relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000474 ! female reproductive system property_value: IAO:0000232 "sometimes oviduct is used interchangeably with follaopian tube. Here they are different - the oviduct connects the gonad to the outside in a variety of animals. The mammal-class fallopian tube is derived from the mullerian duct and connects the gonads/infubdibulum to the uterus" xsd:string property_value: UBPROP:0000001 "A passage through which ova leave the maternal body or pass to an organ communicating with the exterior of the body. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001136", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/oviduct"} property_value: UBPROP:0000003 "In all remaining vertebrates (i.e., coelacanths, lungfishes, amphibians, reptiles, birds, and mammals), the oviduct arises in ontogeny as a longitudinal, groovelike invagination of the coelomic epithelium on the lateral surface of the mesonephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001136", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.687-688", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "in birds divided into infundibulum, magnum, isthmus, uterus, and vagina" xsd:string property_value: UBPROP:0000008 "The only female vertebrates to lack oviducts are the jawless fishes. In these species, the single fused ovary releases eggs directly into the body cavity. The fish eventually extrudes the eggs through small genital pores towards the rear of the body[WP]" xsd:string [Term] id: UBERON:0000995 name: uterus namespace: uberon def: "The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth." [MGI:csmith, MP:0001120] subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim xref: BTO:0001424 xref: CALOHA:TS-1102 xref: EFO:0000975 xref: EMAPA:29915 xref: EV:0100113 xref: FMA:17558 xref: GAID:172 xref: galen:Uterus xref: MA:0000389 xref: MAT:0000127 xref: MESH:D014599 xref: MIAA:0000127 xref: NCIT:C12405 xref: SCTID:181452004 xref: UMLS:C0042149 {source="ncithesaurus:Uterus"} xref: VHOG:0001137 xref: Wikipedia:Uterus is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013515 {source="cjm"} ! subdivision of oviduct relationship: develops_from UBERON:0005795 ! embryonic uterus relationship: immediate_transformation_of UBERON:0005795 ! embryonic uterus relationship: only_in_taxon NCBITaxon:32525 ! Theria relationship: part_of UBERON:0004175 ! internal genitalia property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6a/Female_reproductive_system_lateral_nolabel.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The hollow muscular organ in female mammals in which the blastocyst normally becomes embedded and in which the developing embryo and fetus is nourished. Its cavity opens into the vagina below and into a uterine tube on either side. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001137", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/uterus"} property_value: UBPROP:0000003 "An infundibulum, uterine tube, uterus, and vagina also differentiate along the oviducts of eutherian mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001137", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.678", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "uterine" xsd:string property_value: UBPROP:0000008 "Most animals that lay eggs, such as birds and reptiles, have an oviduct instead of a uterus. In monotremes, mammals which lay eggs and include the platypus, either the term uterus or oviduct is used to describe the same organ, but the egg does not develop a placenta within the mother and thus does not receive further nourishment after formation and fertilization. Marsupials have two uteruses, each of which connect to a lateral vagina and which both use a third, middle 'vagina' which functions as the birth canal. Marsupial embryos form a choriovitelline 'placenta' (which can be thought of as something between a monotreme egg and a 'true' placenta), in which the egg's yolk sac supplies a large part of the embryo's nutrition but also attaches to the uterine wall and takes nutrients from the mother's bloodstream." xsd:string property_value: UBPROP:0000011 "Two uteruses usually form initially in a female fetus, and in placental mammals they may partially or completely fuse into a single uterus depending on the species. In many species with two uteruses, only one is functional. Humans and other higher primates such as chimpanzees, along with horses, usually have a single completely fused uterus, although in some individuals the uteruses may not have completely fused [Wikipedia:Uterus]" xsd:string [Term] id: UBERON:0000997 name: mammalian vulva namespace: uberon def: "External genital organs of the female mammal[WP]." [Wikipedia:Vulva] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "female pudendum" EXACT DEPRECATED [BTO:0003101, doi:10.1002/ca.23705, FMA:20462] synonym: "mammalian vulva" EXACT [] synonym: "puboperineal region" EXACT [FMA:20462] synonym: "pudendum" RELATED DEPRECATED [BTO:0003101, doi:10.1002/ca.23705] synonym: "pudendum femininum" EXACT DEPRECATED [doi:10.1002/ca.23705, FMA:20462, FMA:TA] synonym: "pudendum femininum" RELATED DEPRECATED [doi:10.1002/ca.23705, Wikipedia:Vulva] synonym: "pudendum muliebre" RELATED DEPRECATED [BTO:0003101, doi:10.1002/ca.23705] synonym: "vulva" EXACT [MA:0000395] xref: BTO:0003101 xref: CALOHA:TS-1168 xref: EFO:0000978 xref: EMAPA:36631 xref: EV:0100118 xref: FMA:20462 xref: GAID:383 xref: galen:Vulva xref: MA:0000395 xref: MAT:0000169 xref: MESH:D014844 xref: MIAA:0000169 xref: NCIT:C12408 xref: SCTID:265796001 xref: UMLS:C0042993 {source="ncithesaurus:Vulva"} xref: VHOG:0001458 xref: Wikipedia:Vulva is_a: UBERON:0000062 ! organ is_a: UBERON:0005156 ! reproductive structure relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0005056 ! external female genitalia property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/da/Female_unshaved_genitalia.jpg" xsd:anyURI property_value: UBPROP:0000001 "The external genital organs of the female, including the labia majora, labia minora, clitoris, and vestibule of the vagina. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001458", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/vulva"} property_value: UBPROP:0000007 "vulval" xsd:string [Term] id: UBERON:0000998 name: seminal vesicle namespace: uberon def: "Either of a pair of glandular pouches that lie one on either side of the male reproductive tract posterolateral to the urinary bladder and in the human male secrete a sugar- and protein-containing fluid into the ejaculatory duct." [BTO:0001234, Wikipedia:Seminal_vesicle] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "glandula seminalis" RELATED [BTO:0001234] synonym: "glandula vesiculosa" RELATED [BTO:0001234] synonym: "gonecyst" RELATED [] synonym: "seminal gland" BROAD [] synonym: "vas efferens" RELATED [] synonym: "vesicula seminalis" RELATED [BTO:0001234, Wikipedia:Seminal_vesicle] synonym: "vesiculae seminales" RELATED LATIN [Wikipedia:Seminal_vesicle] synonym: "vesicular gland" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular glands" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesicular seminalis" RELATED [Wikipedia:Seminal_vesicle] synonym: "vesiculæ seminales" RELATED [Wikipedia:Seminal_vesicle] xref: AAO:0010788 xref: BTO:0001234 xref: CALOHA:TS-0919 xref: EFO:0000986 xref: EMAPA:19180 xref: EV:0100106 xref: FMA:19386 xref: GAID:394 xref: MA:0000410 xref: MAT:0000171 xref: MESH:D012669 xref: MIAA:0000171 xref: NCIT:C12787 xref: SCTID:181434004 xref: UMLS:C0036628 {source="ncithesaurus:Seminal_Vesicle"} xref: VHOG:0001379 xref: Wikipedia:Seminal_vesicle is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0006868 ! seminal fluid secreting gland relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia relationship: develops_from UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000473 ! testis relationship: produces UBERON:0010143 ! seminal vesicle fluid property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI property_value: UBPROP:0000001 "Either of a pair of pouchlike glands situated on each side of the male urinary bladder that secrete seminal fluid and nourish and promote the movement of spermatozoa through the urethra. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001379", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/prominence"} property_value: UBPROP:0000003 "(In mammalian testis) Along the way (the sperm travel), three accessory sex glands, the seminal vesicle, prostate, and bulbourethral (Cowper's) gland, respectively, add their secretions as sperm move from the testes to the urethra.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001379", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.556", source="http://bgee.unil.ch/"} property_value: UBPROP:0000009 "The seminal vesicles secrete a significant proportion of the fluid that ultimately becomes semen. Lipofuscin granules from dead epithelial cells give the secretion its yellowish color. About 50-70% of the seminal fluid in humans originates from the seminal vesicles, but is not expelled in the first ejaculate fractions which are dominated by spermatozoa and zinc-rich prostatic fluid." xsd:string [Term] id: UBERON:0000999 name: ejaculatory duct namespace: uberon def: "The Ejaculatory ducts (ductus ejaculatorii) are paired structures in male anatomy, about 2 cm in length. Each ejaculatory duct is formed by the union of the vas deferens with the duct of the seminal vesicle. They pass through the prostate, and empty into the urethra at the Colliculus seminalis. During ejaculation, semen passes through the ducts and exits the body via the penis[WP,unvetted]." [Wikipedia:Ejaculatory_duct] subset: efo_slim subset: uberon_slim synonym: "ductus ejaculatorii" EXACT PLURAL [BTO:0001580] synonym: "ductus ejaculatorii" RELATED LATIN [Wikipedia:Ejaculatory_duct] synonym: "ductus ejaculatorius" EXACT [BTO:0001580] xref: BTO:0001580 xref: CALOHA:TS-0211 xref: EFO:0000985 xref: EMAPA:19088 xref: FMA:19325 xref: GAID:388 xref: MA:0003247 xref: MAT:0000170 xref: MESH:D004543 xref: MIAA:0000170 xref: NCIT:C32493 xref: SCTID:279665005 xref: UMLS:C0013747 {source="ncithesaurus:Ejaculatory_Duct"} xref: Wikipedia:Ejaculatory_duct is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system is_a: UBERON:0015212 ! lateral structure relationship: capable_of_part_of GO:0042713 ! sperm ejaculation relationship: channel_for UBERON:0001968 ! semen relationship: channel_for UBERON:0010143 ! seminal vesicle fluid relationship: channels_from UBERON:0000998 ! seminal vesicle relationship: channels_from UBERON:0001000 ! vas deferens relationship: channels_into UBERON:0000057 ! urethra relationship: in_lateral_side_of UBERON:0000079 ! male reproductive system relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI [Term] id: UBERON:0001000 name: vas deferens namespace: uberon def: "A secretory duct that transports sperm from the testis. In mammals this is a continuation of the epididymis and ends in the prostatic urethra where it terminates to form ejaculatory duct." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MGI:pvb, MP:0002769, Wikipedia:Vas_deferens] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "deferent duct" EXACT [] synonym: "ductus deferens" EXACT [Wikipedia:Vas_deferens] synonym: "sperm duct" RELATED [] synonym: "vas deferen" EXACT [] synonym: "vasa deferentia" RELATED [] xref: BTO:0001427 xref: CALOHA:TS-1105 xref: EFO:0000981 xref: EMAPA:18681 xref: EV:0100105 xref: FMA:19234 xref: GAID:404 xref: galen:VasDeferens xref: MA:0000413 xref: MESH:D014649 xref: MIAA:0000129 xref: NCIT:C12813 xref: SCTID:245467009 xref: UMLS:C0042360 {source="ncithesaurus:Vas_Deferens"} xref: VHOG:0001135 xref: Wikipedia:Vas_deferens is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system relationship: channel_for UBERON:0001968 ! semen relationship: channels_from UBERON:0001301 ! epididymis relationship: channels_into UBERON:0000999 ! ejaculatory duct relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia relationship: only_in_taxon NCBITaxon:32524 ! Amniota relationship: part_of UBERON:0005352 {source="FMA"} ! spermatic cord relationship: part_of UBERON:0006947 ! male genital duct property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d1/Male_anatomy_en.svg" xsd:anyURI property_value: UBPROP:0000003 "The continuation of the archinephric duct, now called the deferent duct, extends caudally to the cloaca or to the part of the mammalian urethra that is derived from the cloaca.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001135", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.670", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Most vertebrates have some form of duct to transfer the sperm from the testes to the urethra. In cartilaginous fish and amphibians, sperm is carried through the archinephric duct, which also partially helps to transport urine from the kidneys. In teleosts, there is a distinct sperm duct, separate from the ureters, and often called the vas deferens, although probably not truly homologous with that in humans. In cartilaginous fishes, the part of the archinephric duct closest to the testis is coiled up to form an epididymis. Below this are a number of small glands secreting components of the seminal fluid. The final portion of the duct also receives ducts from the kidneys in most species. In amniotes, however, the archinephric duct has become a true vas deferens, and is used only for conducting sperm, never urine. As in cartilaginous fish, the upper part of the duct forms the epididymis. In many species, the vas deferens ends in a small sac for storing sperm. The only vertebrates to lack any structure resembling a vas deferens are the primitive jawless fishes, which release sperm directly into the body cavity, and then into the surrounding water through a simple opening in the body wall." xsd:string {source="WP"} [Term] id: UBERON:0001003 name: skin epidermis namespace: uberon def: "The outer epithelial layer of the skin that is superficial to the dermis." [http://orcid.org/0000-0002-6601-2165, ISBN:0073040584] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "epidermis" BROAD [] synonym: "skin" BROAD [] synonym: "vertebrate epidermis" EXACT [] xref: AAO:0000143 xref: BTO:0000404 xref: CALOHA:TS-0283 xref: EFO:0000954 xref: EMAPA:17528 xref: EV:0100153 xref: FMA:70596 xref: GAID:932 xref: MA:0000153 xref: MAT:0000154 xref: MESH:D004817 xref: MIAA:0000154 xref: NCIT:C12708 xref: SCTID:361694003 xref: TAO:0000105 xref: UMLS:C0014520 {source="ncithesaurus:Epidermis"} xref: VHOG:0000077 xref: Wikipedia:Epidermis_(skin) xref: XAO:0000028 xref: ZFA:0000105 is_a: UBERON:0007376 ! outer epithelium is_a: UBERON:3000961 ! external integument structure intersection_of: UBERON:0007376 ! outer epithelium intersection_of: part_of UBERON:0002097 ! skin of body relationship: adjacent_to UBERON:0002067 ! dermis relationship: developmentally_replaces UBERON:0003055 ! periderm relationship: part_of UBERON:0002097 ! skin of body property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A cellular, multilayered epithelium derived from the ectoderm. Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000105", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The outer epithelial layer of the external integument of the body that is derived from the embryonic epiblast.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000143", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship loss: subclass external integument structures (AAO:0000961)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000143", ontology="AAO"} property_value: UBPROP:0000003 "(...) outer epithelia in all metazoan animals are homologous. (...) The ancestor of all metazoans likely had an epidermis with a basal extracellular matrix (ECM), an apical extracellular glycocalyx, and one cilium with a striated rootlet per cell.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000077", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.71-72", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "epidermal" xsd:string property_value: UBPROP:0000008 "Zebrafish epidermis consists only of living cells unlike terrestrial vertebrates in which dead, keratinized cells are present. In terrestrial vertebrates the epidermis often forms an outer keratinized or cornified layer, the stratum corneum. Interaction between the epideris and dermis gives rise to feathers (birds), hair and mammary glands (mammals), teeth and scales (placoid: chondrichthyans; cosmoids, ganoid, cycloid in bony fishes)." xsd:string [Term] id: UBERON:0001004 name: respiratory system namespace: uberon def: "Functional system which consists of structures involved in respiration." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Respiratory_system] subset: efo_slim subset: functional_classification subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "apparatus respiratorius" EXACT [] synonym: "apparatus respiratorius" RELATED [BTO:0000203] synonym: "Atmungssystem" RELATED [BTO:0000203] synonym: "respiratory system" EXACT [] synonym: "systema respiratorium" RELATED LATIN [Wikipedia:Respiratory_system] xref: AAO:0000541 xref: BTO:0000203 xref: CALOHA:TS-1319 xref: EFO:0000804 xref: EHDAA2:0001604 xref: EHDAA:2203 xref: EMAPA:16727 xref: EV:0100036 xref: FMA:7158 xref: GAID:78 xref: MA:0000327 xref: MAT:0000030 xref: MESH:D012137 xref: MIAA:0000030 xref: NCIT:C12779 xref: SCTID:278197002 xref: TAO:0000272 xref: UMLS:C0035237 {source="ncithesaurus:Respiratory_System"} xref: VHOG:0000202 xref: Wikipedia:Respiratory_system xref: XAO:0000117 xref: ZFA:0000272 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system disjoint_from: UBERON:0001007 ! digestive system disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0003016 ! respiratory system process relationship: capable_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5e/Respiratory_system_complete_en.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The anatomical system in which the exchange of oxygen and carbon dioxide between the organism and its environment.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000541", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "There is no doubt that the primitive pattern of vertebrate air-breathing is the buccal pulse pump found in actinopterygian fishes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000202", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.599 and Figure 18-23", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001005 name: respiratory airway namespace: uberon def: "An airway through which respiratory air passes in organisms." [Wikipedia:Trachea] subset: grouping_class subset: uberon_slim synonym: "airway" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "airways" BROAD PLURAL [http://orcid.org/0000-0002-6601-2165] xref: FMA:265130 xref: SCTID:361380005 xref: Wikipedia:Trachea is_a: UBERON:0003103 ! compound organ is_a: UBERON:0004111 ! anatomical conduit relationship: channel_for UBERON:0034874 ! air in respiratory system relationship: part_of UBERON:0001004 ! respiratory system property_value: IAO:0000232 "This class generically groups trachea and analagous structures throughout metazoa. Consider renaming, as the term could be taken to mean lumen of tracheal system (e.g. in SNOMED). As a grouping class this is quite vague, as it is not clear where the airway begins and ends" xsd:string [Term] id: UBERON:0001007 name: digestive system namespace: uberon def: "Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes." [FB:gg, NLM:alimentary+system, Wikipedia:Digestive_system] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "alimentary system" RELATED [] synonym: "alimentary tract" RELATED [] synonym: "gastrointestinal system" RELATED [] synonym: "gut" RELATED [] xref: AAO:0000129 xref: BILA:0000082 xref: BTO:0000058 xref: CALOHA:TS-1293 xref: EFO:0000793 xref: EV:0100056 xref: FBbt:00005055 xref: FMA:7152 xref: GAID:278 xref: galen:DigestiveSystem xref: MA:0002431 xref: MAT:0000018 xref: MESH:D004064 xref: MIAA:0000018 xref: ncithesaurus:Digestive_System xref: SCTID:278859004 xref: TADS:0000170 xref: TAO:0000339 xref: WBbt:0005748 xref: Wikipedia:Digestive_system xref: XAO:0000125 xref: ZFA:0000339 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0022600 ! digestive system process disjoint_from: UBERON:0001009 ! circulatory system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0022600 ! digestive system process relationship: existence_ends_during UBERON:0000066 ! fully formed stage property_value: UBPROP:0000001 "An anatomical system consisting of the alimentary canal and digestive glands responsible for intake, absorption, digestion and excretion of food.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000129", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000007 "digestive" xsd:string property_value: UBPROP:0000012 "many anatomy ontologies consider gastrointestinal system synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001008 name: renal system namespace: uberon def: "The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products." [DOI:10.1371/journal.pone.0099864, GO:0072001] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "excretory system" BROAD [] synonym: "renal or urinary system" RELATED [EHDAA:5901] synonym: "renal/urinary system" RELATED [] synonym: "systema urinaria" EXACT [FMA:7159] synonym: "systema urinarium" EXACT [BTO:0003092] synonym: "urinary system" EXACT [] synonym: "urinary tract" EXACT [] xref: AAO:0010257 xref: BILA:0000015 xref: BTO:0001244 xref: BTO:0003092 xref: CALOHA:TS-1323 xref: EFO:0000803 xref: EHDAA2:0001601 xref: EHDAA:5901 xref: EMAPA:17366 xref: EV:0100095 xref: FBbt:00005056 xref: FMA:7159 xref: GAID:391 xref: galen:UrinaryTract xref: MA:0000325 xref: MAT:0000027 xref: MESH:D014551 xref: MIAA:0000027 xref: NCIT:C12413 xref: SCTID:362204003 xref: TADS:0000162 xref: TAO:0000163 xref: UMLS:C1508753 {source="ncithesaurus:Urinary_System"} xref: VHOG:0000723 xref: WBbt:0005736 xref: Wikipedia:Excretory_system xref: XAO:0000143 xref: ZFA:0000163 is_a: UBERON:8450002 ! excretory system intersection_of: UBERON:8450002 ! excretory system intersection_of: capable_of GO:0097254 ! renal tubular secretion relationship: capable_of GO:0097254 ! renal tubular secretion relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: editor_note "In various sources such as Encyclopedia Britannica, the excretory and urinary systems are indeed the same system (see wikipedia talk page); we merge two BTO classes here" xsd:string property_value: RO:0002161 NCBITaxon:110815 {source="Wikipedia"} property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: UBPROP:0000001 "An anatomical system which consists of organs and tissues which produce, store, and excrete urine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010257", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Evolution of vertebrate renal anatomy appears quite conservative when compared, for example, to evolution of respiratory and cardiovascular systems in vertebrates. Major anatomical changes in vertebrates kidneys separate those of birds and mammals from kidneys of lower vertebrates. General increase in animal size from fish to mammals is reflected by an increase in total number of nephrons per kidney, rather than by constant change in tubular dimensions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000723", ontology="VHOG", source="ISBN:978-3540428541 Kapoor BG, Bhavna Khanna, Ichthyology Handbook (2004) p.406", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels" xsd:string {source="GO"} property_value: UBPROP:0000008 "This definition is inclusive of the organs of the vertebrate renal system, as well as the Malpighian tubules of insects, and allows for future incorporation of structures such as the antennal glands of crustaceans" xsd:string {source="DOI:10.1371/journal.pone.0099864"} [Term] id: UBERON:0001009 name: circulatory system namespace: uberon def: "Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]." [Wikipedia:Circulatory_system] subset: uberon_slim synonym: "systema cardiovasculare" RELATED LATIN [Wikipedia:Circulatory_system] xref: AAO:0000959 xref: CALOHA:TS-2103 xref: VHOG:0001248 xref: Wikipedia:Circulatory_system is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0001016 ! nervous system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0003013 ! circulatory system process relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI property_value: IAO:0000232 "the cardiovascular system and the lymphatic system are parts of the circulatory system" xsd:string property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: RO:0002161 NCBITaxon:6073 property_value: RO:0002161 NCBITaxon:6157 property_value: RO:0002174 NCBITaxon:6231 {notes="WBbt coelomocyte currently classified as circulating cell"} property_value: UBPROP:0000001 "Anatomical system of ion binding, a pumping mechanism, and an efficient vascular system; consisting of the blood, heart, and blood and lymph vessels, respectively.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000959", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "We should divest ourselves of the view that earlier vertebrate groups were 'on their way' to becoming mammals, as clearly they were not such visionaries. Neither were their systems 'imperfect' as earlier anatomists thought. Instead, their circulatory systems served them well to address the ecological demands arising from their lifestyles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001248", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.493", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001010 name: diaphysis of ulna namespace: uberon def: "The body of the ulna at its upper part is prismatic in form, and curved so as to be convex behind and lateralward; its central part is straight; its lower part is rounded, smooth, and bent a little lateralward. It tapers gradually from above downward, and has three borders and three surfaces." [Wikipedia:Body_of_ulna] synonym: "body of ulna" EXACT [FMA:33760] synonym: "corpus ulnae" EXACT [FMA:33760] synonym: "shaft of ulna" EXACT [FMA:33760] synonym: "shaft of ulna" RELATED [Wikipedia:Body_of_ulna] synonym: "supinator crest" RELATED [Wikipedia:Body_of_ulna] synonym: "ulnar diaphysis" EXACT [FMA:33760] xref: FMA:33760 xref: NCIT:C120676 xref: SCTID:302520004 xref: Wikipedia:Body_of_ulna is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0001424 ! ulna relationship: part_of UBERON:0001424 ! ulna [Term] id: UBERON:0001012 name: head of radius namespace: uberon def: "The head of the radius has a cylindrical form, and on its upper surface is a shallow cup or fovea for articulation with the capitulum (or capitellum) of the humerus. The circumference of the head is smooth; it is broad medially where it articulates with the radial notch of the ulna, narrow in the rest of its extent, which is embraced by the annular ligament. The deepest point in the fovea is not axi-symmetric with the long axis of the radius, creating a cam effect during pronation and supination[WP]." [Wikipedia:Head_of_radius] subset: pheno_slim synonym: "caput radii" RELATED LATIN [Wikipedia:Head_of_radius] synonym: "radial head" EXACT [FMA:33773] xref: FMA:33773 xref: galen:HeadOfRadius xref: SCTID:181941003 xref: Wikipedia:Head_of_radius is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: part_of UBERON:0001490 {source="FMA"} ! elbow joint relationship: part_of UBERON:0004413 {source="FMA"} ! proximal epiphysis of radius property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/47/Gray214.png" xsd:anyURI [Term] id: UBERON:0001013 name: adipose tissue namespace: uberon def: "Portion of connective tissue composed of adipocytes enmeshed in areolar tissue." [http://orcid.org/0000-0002-6601-2165, MESH:A10.165.114, MGI:cwg, MP:0000003, Wikipedia:Adipose_tissue] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "adipose" RELATED [BTO:0001487] synonym: "bodyfat" RELATED [BTO:0001487] synonym: "fat" EXACT [MA:0000009] synonym: "fat tissue" EXACT [] synonym: "fatty depot" RELATED [] synonym: "fatty tissue" EXACT [] xref: AAO:0000001 xref: AEO:000020 xref: BTO:0001487 xref: CALOHA:TS-0013 xref: EFO:0000790 xref: EHDAA2:0003120 xref: EMAPA:35112 xref: EV:0100381 xref: FMA:20110 xref: GAID:920 xref: galen:FattyTissue xref: MA:0000009 xref: MAT:0000015 xref: MESH:D000273 xref: MIAA:0000015 xref: NCIT:C12472 xref: SCTID:55603005 xref: TAO:0002134 xref: UMLS:C0001527 {source="ncithesaurus:Adipose_Tissue"} xref: VHOG:0001284 xref: Wikipedia:Adipose_tissue xref: XAO:0003049 xref: ZFA:0005345 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: composed_primarily_of CL:0000136 ! fat cell disjoint_from: UBERON:0003714 ! neural tissue relationship: composed_primarily_of CL:0000136 ! fat cell property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Connective tissue in which fat is stored.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002134", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Tissue that contains adipocytes, used for cushioning, thermal insulation, lubrication (primarily in the pericardium) and energy storage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000001", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000001", ontology="AAO"} property_value: UBPROP:0000003 "Adipose tissue is unique to vertebrates. It is found in mostmammals, birds, reptiles and amphibians, and a variety is found in some species of fish. Furthermore, in insects the fat body found in larvae as well as in adults shares some homology with adipose tissue.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001284", ontology="VHOG", source="DOI:10.1017/S0029665107005423 Haugen F, Drevon CA, The interplay between nutrients and the adipose tissue. The Proceedings of the Nutrition Society (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "adipose" xsd:string property_value: UBPROP:0000008 "In humans, adipose tissue is located beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow) and in breast tissue. Adipose tissue is found in specific locations, which are referred to as adipose depots. Adipose tissue contains several cell types, with the highest percentage of cells being adipocytes, which contain fat droplets. Other cell types include fibroblasts, macrophages, and endothelial cells. Adipose tissue contains many small blood vessels.; Mice have eight major adipose depots, four of which are within the abdominal cavity. The paired gonadal depots are attached to the uterus and ovaries in females and the epididymis and testes in males; the paired retroperitoneal depots are found along the dorsal wall of the abdomen, surrounding the kidney, and, when massive, extend into the pelvis. The mesenteric depot forms a glue-like web that supports the intestines, and the omental depot, which originates near the stomach and spleen, and, when massive, extends into the ventral abdomen." xsd:string property_value: UBPROP:0000012 "in FMA this is dense irregular connective tissue" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001015 name: musculature namespace: uberon def: "A subdivision of the muscular system corresponding to a subdisivision of an organism." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Muscular_system] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "muscle group" EXACT [] synonym: "muscle system" RELATED [] synonym: "muscles" RELATED [] synonym: "muscles set" EXACT [] synonym: "musculature" EXACT [] synonym: "musculature system" RELATED [] synonym: "musculi" EXACT LATIN [FMA:32558, FMA:TA] synonym: "set of muscles" EXACT [FMA:32558] synonym: "set of skeletal muscles" EXACT [MA:0000165] xref: AAO:0011066 xref: BTO:0000887 xref: EFO:0001949 xref: EMAPA:32715 xref: EMAPA:35577 xref: FMA:32558 xref: MA:0000165 xref: NCIT:C13056 xref: TAO:0000548 xref: UMLS:C0026845 {source="ncithesaurus:Muscle"} xref: VSAO:0005038 xref: WBbt:0005737 xref: Wikipedia:Muscular_system xref: ZFA:0000548 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 ! organ system subdivision relationship: composed_primarily_of UBERON:0001630 ! muscle organ relationship: part_of UBERON:0000383 ! musculature of body property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e5/Muscles_anterior_labeled.png" xsd:anyURI property_value: RO:0002171 UBERON:0001474 property_value: UBPROP:0000012 "In FMA this is classified as a set of organs. ZFA musculature system has subtypes, so it is classified here. WBbt muscular system has subtypes so it goes here. Note that we use the MA term set of skeletal muscles here as it seems most appropriate (*not* MA:musculature). AAO is generally confused here." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001016 name: nervous system namespace: uberon def: "The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]." [BIRNLEX:844, ISBN:0-14-051288-8, ISBN:3110148986, NLM:nervous+system, WB:rynl, Wikipedia:Nervous_system, ZFIN:curator] subset: cumbo subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerve net" NARROW [Wikipedia:Nerve_net] synonym: "neurological system" EXACT [GO:0050877] synonym: "systema nervosum" RELATED LATIN [Wikipedia:Nervous_system] xref: AAO:0000324 xref: BILA:0000079 xref: BIRNLEX:844 xref: BTO:0001484 xref: CALOHA:TS-1313 xref: EFO:0000802 xref: EHDAA2:0001246 xref: EHDAA:826 xref: EMAPA:16469 xref: EV:0100162 xref: FBbt:00005093 xref: FMA:7157 xref: GAID:466 xref: MA:0000016 xref: MAT:0000026 xref: MESH:D009420 xref: MIAA:0000026 xref: NCIT:C12755 xref: neuronames:3236 xref: SCTID:278196006 xref: TAO:0000396 xref: UMLS:C0027763 {source="ncithesaurus:Nervous_System"} xref: VHOG:0000402 xref: WBbt:0005735 xref: Wikipedia:Nervous_system xref: XAO:0000177 xref: ZFA:0000396 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0001033 ! gustatory system disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0050877 ! nervous system process relationship: composed_primarily_of CL:0002319 ! neural cell relationship: develops_from UBERON:0016880 ! future nervous system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part CL:0000540 ! neuron relationship: immediate_transformation_of UBERON:0016880 {source="Bgee:AN"} ! future nervous system relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b2/TE-Nervous_system_diagram.svg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/ba/Nervous_system_diagram.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:6040 property_value: UBPROP:0000001 "A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000396", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Anatomical system consisting of nerve bodies and nerve fibers which regulate the response of the body to external and internal stimuli.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000324", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Nervous systems evolved in the ancestor of Eumetazoa.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000402", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.117", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "nervous" xsd:string property_value: UBPROP:0000007 "neural" xsd:string [Term] id: UBERON:0001017 name: central nervous system namespace: uberon def: "The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord." [GO:0021551, http://www.frontiersinzoology.com/content/7/1/29, https://sourceforge.net/p/geneontology/ontology-requests/11422/] subset: cumbo subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrospinal axis" NARROW [FMA:55675] synonym: "CNS" EXACT ABBREVIATION [] synonym: "neuraxis" RELATED [FMA:55675] synonym: "systema nervosum centrale" EXACT LATIN [FMA:55675, FMA:TA] xref: AAO:0000090 xref: BAMS:CNS xref: BILA:0000080 xref: BIRNLEX:1099 xref: BTO:0000227 xref: CALOHA:TS-0150 xref: EFO:0000908 xref: EHDAA2:0000225 xref: EHDAA:828 xref: EMAPA:16470 xref: EMAPA:16754 xref: EV:0100163 xref: FBbt:00005094 xref: FMA:55675 xref: GAID:570 xref: MA:0000167 xref: MAT:0000457 xref: MESH:D002490 xref: NCIT:C12438 xref: neuronames:854 xref: SCTID:278199004 xref: TAO:0000012 xref: UMLS:C0927232 {source="ncithesaurus:Central_Nervous_System", source="BIRNLEX:1099"} xref: VHOG:0000293 xref: Wikipedia:Central_nervous_system xref: XAO:0000215 xref: ZFA:0000012 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0011216 {source="FBbt", source="cjm"} ! organ system subdivision relationship: develops_from UBERON:0001049 {gci_relation="part_of", gci_filler="NCBITaxon:7742", evidence="definitional"} ! neural tube relationship: develops_from UBERON:0016879 ! future central nervous system relationship: immediate_transformation_of UBERON:0016879 {source="Bgee:AN"} ! future central nervous system relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001016 ! nervous system property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: UBPROP:0000001 "Part of the nervous system which includes the brain and spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000090", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain and spinal cord. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000012", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO)." xsd:string {source="BIRNLEX:1099"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000293", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28 (reference 1), ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165 (reference 2), DOI:10.1016/j.cell.2007.02.040 Denes AS, Jekely G, Steinmetz PRH, Raible F, Snyman H, Prud'homme B, Ferrier DEK, Balavoine G and Arendt D, Molecular architecture of annelid nerve cord supports common origin of nervous system centralization in Bilateria. Cell (2007) (reference 3)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001019 name: nerve fasciculus namespace: uberon def: "A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, as of muscle or nerve (American Heritage Dictionary 4th ed)." [BIRNLEX:872, FBbt:00005101] subset: uberon_slim synonym: "fascicle" BROAD [FBbt:00005101] synonym: "fasciculus" EXACT LATIN [] synonym: "nerve bundle" EXACT [FMA:12235] synonym: "nerve fasciculus" EXACT [FMA:12235] synonym: "nerve fiber tract" RELATED [BTO:0002191] synonym: "neural fasciculus" EXACT [FMA:12235] xref: BIRNLEX:872 xref: BTO:0002191 xref: EMAPA:36605 xref: FMA:12235 xref: NCIT:C32586 xref: TGMA:0000088 xref: UMLS:C1185741 {source="ncithesaurus:Fascicle"} xref: Wikipedia:Nervous_system_fascicle is_a: UBERON:0000122 ! neuron projection bundle property_value: editor_note "note FBbt class not disjoint from tract. Consider merging with 'neuron projection bundle'" xsd:string [Term] id: UBERON:0001021 name: nerve namespace: uberon def: "An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures." [FBbt:00005105, http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nerves" EXACT PLURAL [TAO:0007009] synonym: "neural subtree" RELATED [FMA:65132] synonym: "peripheral nerve" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0011070 xref: AEO:0000137 xref: BAMS:n xref: BIRNLEX:1615 xref: BSA:0000098 xref: BTO:0000925 xref: BTO:0001027 xref: CALOHA:TS-0772 xref: EHDAA2:0003137 xref: EHDAA:2851 xref: EHDAA:3776 xref: EHDAA:4657 xref: EMAPA:32808 xref: EMAPA:32815 xref: EV:0100371 xref: FBbt:00005105 xref: FMA:65132 xref: FMA:65239 xref: GAID:747 xref: GAID:758 xref: galen:Nerve xref: MA:0000217 xref: MA:0000228 xref: MESH:D010525 xref: NCIT:C12466 xref: NCIT:C12768 xref: NLX:147826 xref: SCTID:244457007 xref: SCTID:256864008 xref: TAO:0007009 xref: UMLS:C0027740 {source="ncithesaurus:Nerve"} xref: UMLS:C0031119 {source="ncithesaurus:Peripheral_Nerve"} xref: VHOG:0000901 xref: Wikipedia:Nervous_system xref: XAO:0000204 xref: XAO:0003047 xref: ZFA:0007009 is_a: UBERON:0000122 {source="FBbt"} ! neuron projection bundle relationship: has_developmental_contribution_from UBERON:0002342 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! neural crest relationship: has_quality PATO:0002045 ! dendritic relationship: part_of UBERON:0000010 ! peripheral nervous system property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A portion of tissue which is a fasiculated group of axons.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0007009", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000007 "nervous" xsd:string [Term] id: UBERON:0001027 name: sensory nerve namespace: uberon def: "A nerve that transmits from sensory receptors on the surface of the body to the central nervous system." [UBERON:cjm, Wikipedia:Sensory_nerve] subset: pheno_slim subset: uberon_slim synonym: "afferent nerve" RELATED [] synonym: "nervus sensorius" EXACT LATIN [Wikipedia:Sensory_nerve] xref: AEO:0000201 xref: EHDAA2:0003200 xref: FBbt:00005136 xref: FMA:5868 xref: Wikipedia:Sensory_nerve is_a: UBERON:0001021 ! nerve relationship: has_part CL:0000526 {source="AEO"} ! afferent neuron [Term] id: UBERON:0001028 name: diaphysis of radius namespace: uberon def: "A diaphysis that is part of a radius bone[Automatically generated definition]." [OBOL:automatic, Wikipedia:Body_of_radius] subset: pheno_slim synonym: "body of radius" EXACT [FMA:33782] synonym: "corpus radii" EXACT [FMA:33782] synonym: "radial diaphysis" EXACT [FMA:33782] synonym: "radial shaft" RELATED [Wikipedia:Body_of_radius] synonym: "shaft of radius" EXACT [FMA:33782] synonym: "shaft of radius" RELATED [Wikipedia:Body_of_radius] xref: FMA:33782 xref: NCIT:C120674 xref: SCTID:302518002 xref: Wikipedia:Body_of_radius is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0001423 ! radius bone relationship: part_of UBERON:0001423 ! radius bone property_value: UBPROP:0000001 "The body of the radius (or shaft of radius) is prismoid in form, narrower above than below, and slightly curved, so as to be convex lateralward. It presents three borders and three surfaces[Wikipedia:Body_of_radius]." xsd:string {source="Wikipedia:Body_of_radius"} [Term] id: UBERON:0001032 name: sensory system namespace: uberon def: "Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information." [Wikipedia:Sensory_system] subset: efo_slim subset: uberon_slim subset: vertebrate_core synonym: "organa sensuum" EXACT LATIN [FMA:75259, FMA:TA] synonym: "organa sensuum" RELATED LATIN [Wikipedia:Sensory_system] synonym: "sense organ subsystem" EXACT [] synonym: "sense organs" EXACT [FMA:75259] synonym: "sense organs set" EXACT [FMA:75259] synonym: "sensory organ system" RELATED [] synonym: "sensory subsystem" EXACT [] synonym: "sensory systems" EXACT PLURAL [TAO:0000282] synonym: "set of sense organs" RELATED [FMA:75259] xref: AAO:0000555 xref: BAMS:SEN xref: BILA:0000099 xref: EFO:0000805 xref: EHDAA2:0003094 xref: EMAPA:16192 xref: FBbt:00007692 xref: FMA:75259 xref: MA:0002442 xref: MAT:0000031 xref: MIAA:0000031 xref: NLXANAT:090816 xref: TAO:0000282 xref: VHOG:0001674 xref: Wikipedia:Sensory_system xref: XAO:0003194 xref: ZFA:0000282 is_a: UBERON:0015203 ! non-connected functional system relationship: capable_of_part_of GO:0007600 ! sensory perception relationship: overlaps UBERON:0001016 ! nervous system relationship: part_of UBERON:0004456 ! entire sense organ system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c0/Gray722.png" xsd:anyURI property_value: UBPROP:0000003 "An early step in the evolution of neural crest, therefore, may have been the origin of a specific dorsal neural cell population contributing to sensory processing; this would predate the divergence of the amphioxus and vertebrate lineages.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001674", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "note the distinct between entire sensory system and individual system. this reconciles is_a and part_of distinctions between ssAOs" xsd:string [Term] id: UBERON:0001033 name: gustatory system namespace: uberon def: "The sensory system for the sense of taste." [NLXANAT:090803] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gustatory organ system" EXACT [] synonym: "taste system" EXACT [] xref: AAO:0010577 xref: BILA:0000143 xref: EFO:0000830 xref: FMA:7194 xref: MA:0002446 xref: MAT:0000275 xref: MIAA:0000275 xref: neuronames:2889 xref: NLXANAT:090803 xref: SCTID:423940004 xref: TAO:0001101 xref: Wikipedia:Gustatory_system xref: XAO:0003197 xref: ZFA:0001101 is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of_part_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste disjoint_from: UBERON:0001434 ! skeletal system disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of_part_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000001 "The sensory system for the sense of taste[NLXANAT:090803]." xsd:string {source="NLXANAT:090803"} property_value: UBPROP:0000001 "The sensory system used for the sense of taste.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010577", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000007 "gustatory" xsd:string property_value: UBPROP:0000012 "in ZFA and MA this is a subtype of sensory system. we should change sensory system to disambiguate parts and wholes" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0001040 name: yolk sac namespace: uberon def: "A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]." [Wikipedia:Yolk_sac] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "saccus vitellinus" RELATED LATIN [Wikipedia:Yolk_sac] synonym: "vesicula umbilicalis" RELATED LATIN [Wikipedia:Yolk_sac] xref: BTO:0001471 xref: CALOHA:TS-1130 xref: EFO:0003078 xref: EHDAA2:0002212 xref: EHDAA:164 xref: EMAPA:16085 xref: FMA:87180 xref: GAID:1301 xref: MESH:D015017 xref: NCIT:C14128 xref: SCTID:362845002 xref: UMLS:C0043425 {source="ncithesaurus:Yolk_Sac"} xref: VHOG:0000830 xref: Wikipedia:Yolk_sac is_a: UBERON:0005292 ! extraembryonic tissue is_a: UBERON:0005631 {seeAlso="https://github.com/obophenotype/uberon/issues/635"} ! extraembryonic membrane is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: has_developmental_contribution_from UBERON:0000925 {source="ISBN:0073040584"} ! endoderm relationship: has_developmental_contribution_from UBERON:0004872 {source="ISBN:0073040584"} ! splanchnic layer of lateral plate mesoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/17/Gray22.png" xsd:anyURI property_value: editor_note "consider splitting class" xsd:string property_value: UBPROP:0000001 "One of the extraembryonic fetal membranes that balloons out from the fetal midgut. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000830", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/yolk+sac"} property_value: UBPROP:0000001 "the extraembryonic tissue membrane, formed from the visceral endoderm and the extraembryonic mesoderm, which is located ventral to the embryonic disc and is connected to the presumptive midgut of the embryo; the yolk that it contains is the site of embryonic hematopoiesis and vitelline circulation is involved in early embryonic circulation; it is the origin of the primordial germ cells" xsd:string {source="MP:0001718"} property_value: UBPROP:0000003 "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000830", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.187", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In therians, a structure homologous to the yolk sac is is present, but contains no yolk platelets. Instead it is filled with fluid [ISBN:0073040584 (Vertebrates, Kardong)]" xsd:string [Term] id: UBERON:0001041 name: foregut namespace: uberon def: "Anterior subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165] subset: developmental_classification subset: pheno_slim subset: uberon_slim synonym: "praeenteron" RELATED LATIN [Wikipedia:Foregut] synonym: "proenteron" RELATED LATIN [Wikipedia:Foregut] xref: AAO:0011042 xref: BILA:0000085 xref: BTO:0000507 xref: EHDAA2:0000557 xref: EHDAA:520 xref: EMAPA:16548 xref: FBbt:00005379 xref: FMA:45616 xref: MA:0001526 xref: NCIT:C34180 xref: SCTID:361409009 xref: TGMA:0001014 xref: UMLS:C0231051 {source="ncithesaurus:Foregut"} xref: VHOG:0000285 xref: Wikipedia:Foregut xref: XAO:0000232 is_a: UBERON:0004921 ! subdivision of digestive tract property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9a/Gray27.png" xsd:anyURI property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. In vertebrates the term may refer to a developmental structure" xsd:string property_value: UBPROP:0000001 "The anterior portion of the primitive digestive tube of the embryo that lies cephalic to the junction of the yolk stalk, consists of endodermal tissue, and gives rise to the the pharynx, lower respiratory system, esophagus, stomach, duodenum proximal to the biliary tract, liver, pancreas, biliary tract, and gall bladder." xsd:string {source="MP:0000474"} property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000285", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001042 name: chordate pharynx namespace: uberon def: "A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]." [http://www.feedexp.org] comment: Consider generalizing to deuterostome pharynx subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "pharynx" BROAD SENSU [FMA:46688] xref: AAO:0000967 xref: BTO:0001049 xref: CALOHA:TS-0785 xref: EFO:0000836 xref: EHDAA2:0001458 xref: EHDAA:2947 xref: EMAPA:16706 xref: EV:0100065 xref: FMA:46688 xref: GAID:155 xref: galen:Pharynx xref: MA:0000432 xref: MESH:D010614 xref: NCIT:C12425 xref: SCTID:181211006 xref: TAO:0000056 xref: UMLS:C0031354 {source="ncithesaurus:Pharynx"} xref: VHOG:0000462 xref: Wikipedia:Pharynx xref: XAO:0003227 xref: ZFA:0000056 is_a: UBERON:0006562 ! pharynx relationship: continuous_with UBERON:0001043 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! esophagus relationship: develops_from UBERON:0009145 {source="EHDAA2"} ! pharyngeal region of foregut relationship: distally_connected_to UBERON:0001043 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! esophagus relationship: has_skeleton UBERON:0008895 {gci_relation="part_of", gci_filler="NCBITaxon:89593"} ! splanchnocranium relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0001004 ! respiratory system property_value: UBPROP:0000001 "A funnel-shaped fibromuscular tube that conducts food to the ESOPHAGUS, and air to the LARYNYX and LUNGS. It is located posterior to the NASAL CAVITY; ORAL CAVITY; and LARYNX, and extends from the SKULL BASE to the inferior border of the CRICOID CARTILAGE anteriorly and to the inferior border of the C6 vertebra posteriorly. It is divided into the NASOPHARYNX; OROPHARYNX; and HYPOPHARYNX (laryngopharynx)[MESH:A03.867]." xsd:string {source="MESH:A03.867"} property_value: UBPROP:0000001 "Anatomical cavity bounded by the derivatives of the branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000056", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Swollen region of the anterior foregut, posterior to the mouth and anterior to the liver; its walls form the jaws and gills[ZFA:0000056, ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"} property_value: UBPROP:0000001 "The portion of the alimentary canal between the mouth and the oesophagus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000462", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000002 "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: develops_from respiratory system (UBERON:0001004)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO"} property_value: UBPROP:0000002 "relationship type change: part_of_proxy respiratory system (AAO:0000541) CHANGED TO: part_of respiratory system (UBERON:0001004)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000967", ontology="AAO"} property_value: UBPROP:0000003 "(...) the earliest vertebrates possessed unjointed internal and external branchial arches, and musculature encircling the pharynx.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000462", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) Box essay 13.1 and Box figure I, p.502-503", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "MA/FMA pharynx not part of digestive/alimentary system, we are consistent with this scheme" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001043 name: esophagus namespace: uberon def: "Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993)." [http://www.rivm.nl/interspeciesinfo/inter/oesophagus/, Wikipedia:Esophagus] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gullet" EXACT [] synonym: "oesophagus" EXACT [] xref: AAO:0000145 xref: ANISEED:1235301 xref: BTO:0000959 xref: CALOHA:TS-0700 xref: EFO:0000835 xref: EHDAA2:0001285 xref: EHDAA:2937 xref: EMAPA:16833 xref: EV:0100069 xref: FMA:7131 xref: GAID:291 xref: galen:Esophagus xref: MA:0000352 xref: MAT:0000048 xref: MESH:D004947 xref: MIAA:0000048 xref: NCIT:C12389 xref: SCTID:181245004 xref: TAO:0000204 xref: UMLS:C0014876 {source="ncithesaurus:Esophagus"} xref: VHOG:0000450 xref: Wikipedia:Esophagus xref: XAO:0000127 xref: ZFA:0000204 is_a: UBERON:0004921 ! subdivision of digestive tract is_a: UBERON:0005178 ! thoracic cavity element is_a: UBERON:0013765 ! digestive system element relationship: develops_from UBERON:0001041 ! foregut relationship: distally_connected_to UBERON:0000945 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="only in species that have a stomach"} ! stomach relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0004908 ! upper digestive tract relationship: proximally_connected_to UBERON:0001042 ! chordate pharynx property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI property_value: UBPROP:0000001 "Anterior end of the alimentary canal lined with smooth muscle. Bounded anteriorly by a constriction in the pharynx. Bounded posteriorly by and increase in circular and/or longitudinal smooth muscle associated with the stomach.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000145", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The few structural specializations in (adult lampreys) pharynx include complex valves on the external gill openings that direct the tidal flow, and the division of the ancestral pharynx into an oesophagus and a respiratory pharynx.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000450", ontology="VHOG", source="DOI:10.1111/j.1096-3642.1996.tb01658.x Mallatt J, Ventilation and the origin of jawed vertebrates: a new mouth. Zoological Journal of the Linnean Society (1996)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "esophageal" xsd:string property_value: UBPROP:0000012 "esophagus NOT part of gut in MA. part of gut in ZFA. part_of gut (via UGIT) in FMA. Consider splitting. Interspecies: The human oesophagus is 25 cm long and has a diameter of ca. 2 cm. Only little information was found on the oesophagus in rat, rabbit and pig. The oesophagus of rat (75 x 2 mm) and rabbit has no mucous glands and the cardia of the stomach has a well-developed sphincter, which prevents them from vomiting (Hebel and Stromberg, 1988; Manning et al., 1994). Morphologically the oesophagus is similar in man and pig; both are omnivores and have a non-keratinised epithelium, submucous glands and similar membrane enzymes. Like in humans, pigs can suffer from reflux oesophagitis and stress ulceration of the oesophagus. The pig oesophagus may therefore be a good model for investigation compared to the human oesophagus (Christie et al., 1995)" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001045 name: midgut namespace: uberon def: "Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]." [GO:0007494, Wikipedia:Midgut] subset: developmental_classification subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "mesenteron" RELATED LATIN [Wikipedia:Midgut] xref: BILA:0000086 xref: BTO:0000863 xref: EFO:0001950 xref: EHDAA2:0001185 xref: EHDAA:983 xref: EMAPA:16255 xref: FBbt:00005383 xref: FMA:45617 xref: MA:0001564 xref: NCIT:C34210 xref: SCTID:361410004 xref: TGMA:0001036 xref: UMLS:C0231052 {source="ncithesaurus:Midgut"} xref: VHOG:0000290 xref: Wikipedia:Midgut xref: XAO:0000103 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: part_of RO:0002577 ! system relationship: proximally_connected_to UBERON:0001041 ! foregut property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3d/Illu_small_intestine.jpg" xsd:anyURI property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future. We may explicitly make this a developmental class" xsd:string property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000290", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In humans: originates from the foregut at the opening of the bile duct into the duodenum and continues through the small intestine and much of the large intestine until the transition to the hindgut about two-thirds of the way through the transverse colon" xsd:string {source="WP"} property_value: UBPROP:0000012 "in FMA this represents an embryonic region." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001046 name: hindgut namespace: uberon def: "The caudalmost subdivision of a digestive tract." [http://orcid.org/0000-0002-6601-2165] subset: developmental_classification subset: pheno_slim subset: uberon_slim synonym: "metenteron" RELATED LATIN [Wikipedia:Hindgut] xref: AAO:0011052 xref: BILA:0000087 xref: BTO:0000510 xref: EHDAA2:0000779 xref: EHDAA:975 xref: EMAPA:16715 xref: FBbt:00005384 xref: FMA:45618 xref: MA:0001527 xref: NCIT:C34188 xref: SCTID:362856002 xref: TGMA:0001020 xref: UMLS:C0231053 {source="ncithesaurus:Hindgut"} xref: VHOG:0000459 xref: Wikipedia:Hindgut xref: XAO:0000104 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: develops_from UBERON:0003104 {source="Wikipedia"} ! mesenchyme relationship: part_of RO:0002577 ! system relationship: proximally_connected_to UBERON:0001045 ! midgut property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray472.png" xsd:anyURI property_value: editor_note "Note we define this generically to include invertebrates (partly for consistency with GO), but the class may be split in future (vertebrates have some contribution from NC - https://github.com/obophenotype/uberon/wiki/The-neural-crest). We may explicitly make this a developmental class" xsd:string property_value: UBPROP:0000001 "the caudal portion of the primitive digestive tube of the embryo" xsd:string {source="MP:0008786"} property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000459", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in FMA this class has no children. In MA it has a single child hindgut epithelium" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001048 name: primordium namespace: uberon def: "Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]." [BTO:0001886, FB:DJS, FB:FBrf0089570, http://flybase.org/reports/FBrf0178740.html] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "bud" RELATED [] synonym: "future organ" RELATED [] synonym: "placode" RELATED [FBbt:00005495] synonym: "primordia" RELATED PLURAL [XAO:0003043] synonym: "rudiment" RELATED [] xref: AEO:0000171 xref: BTO:0001886 xref: EFO:0001652 xref: EHDAA2:0003171 xref: FBbt:00005495 xref: FMA:86589 xref: MAT:0000482 xref: NCIT:C34275 xref: UMLS:C0678727 {source="ncithesaurus:Primordium"} xref: Wikipedia:Primordium xref: XAO:0003043 is_a: UBERON:0005423 {source="EHDAA2"} ! developing anatomical structure relationship: part_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:0001049 name: neural tube namespace: uberon def: "In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]." [Wikipedia:Neural_tube] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "neural primordium" RELATED [] synonym: "presumptive central nervous system" RELATED [] synonym: "tubus neuralis" RELATED LATIN [Wikipedia:Neural_tube] xref: AAO:0010617 xref: BTO:0001057 xref: CALOHA:TS-2371 xref: DHBA:10154 xref: EHDAA2:0001254 xref: EHDAA:2869 xref: EHDAA:908 xref: EMAPA:16164 xref: EMAPA:16757 xref: FMA:293882 xref: MAT:0000069 xref: MESH:D054259 xref: MIAA:0000069 xref: NCIT:C34226 xref: neuronames:1365 xref: SCTID:362852000 xref: TAO:0001135 xref: UMLS:C0231024 {source="ncithesaurus:Neural_Tube"} xref: VHOG:0000307 xref: Wikipedia:Neural_tube xref: XAO:0003204 xref: ZFA:0001135 is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0016879 ! future central nervous system relationship: develops_from UBERON:0005068 ! neural rod property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: UBPROP:0000001 "Hollow epithelial tube on dorsal side of the embryo that develops into the central nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010617", ontology="AAO", source="AAO:JOR"} property_value: UBPROP:0000001 "The dorsal tubular structure in the vertebrate embryo that develops into the brain and spinal cord. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000307", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/neural+tube"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000307", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium" xsd:string {source="GO:0021915"} [Term] id: UBERON:0001052 name: rectum namespace: uberon def: "The terminal portion of the intestinal tube, terminating with the anus." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MP:0000492] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "intestinum rectum" RELATED [BTO:0001158] synonym: "rectal sac" RELATED [] synonym: "terminal portion of intestine" EXACT [] synonym: "terminal portion of large intestine" RELATED [] xref: AAO:0010401 xref: BTO:0001158 xref: CALOHA:TS-1180 xref: EFO:0000848 xref: EHDAA2:0001592 xref: EHDAA:5836 xref: EMAPA:17896 xref: EV:0100081 xref: FMA:14544 xref: GAID:311 xref: galen:Rectum xref: MA:0000336 xref: MAT:0000050 xref: MESH:D012007 xref: MIAA:0000050 xref: NCIT:C12390 xref: SCTID:181261002 xref: UMLS:C0034896 {source="ncithesaurus:Rectum"} xref: VHOG:0001751 xref: Wikipedia:Rectum xref: XAO:0000238 is_a: UBERON:0004921 {order="4", source="cjm"} ! subdivision of digestive tract relationship: continuous_with UBERON:0001159 ! sigmoid colon relationship: contributes_to_morphology_of UBERON:0000059 ! large intestine relationship: distalmost_part_of UBERON:0000059 {source="ISBN:0073040584"} ! large intestine relationship: part_of UBERON:0000059 {source="MA"} ! large intestine relationship: part_of UBERON:0006866 ! terminal part of digestive tract relationship: part_of UBERON:0012361 {source="EHDAA2"} ! internal anal region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The terminal portion of the large intestine between the ileo-pelvic colon and the anus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001751", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "rectal" xsd:string property_value: UBPROP:0000008 "In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html" xsd:string [Term] id: UBERON:0001062 name: anatomical entity namespace: uberon def: "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." [FMA:62955, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level xref: AAO:0010841 xref: AEO:0000000 xref: BILA:0000000 xref: BIRNLEX:6 xref: CARO:0000000 xref: EHDAA2:0002229 xref: FBbt:10000000 xref: FMA:62955 xref: HAO:0000000 xref: MA:0000001 xref: NCIT:C12219 xref: TAO:0100000 xref: TGMA:0001822 xref: UMLS:C1515976 {source="ncithesaurus:Anatomic_Structure_System_or_Substance"} xref: WBbt:0000100 xref: XAO:0000000 xref: ZFA:0100000 is_a: BFO:0000004 ! independent continuant relationship: part_of UBERON:0003942 {gci_filler="GO:0050975", gci_relation="capable_of_part_of"} ! somatosensory system relationship: part_of UBERON:0003942 {gci_relation="capable_of_part_of", gci_filler="GO:0019233"} ! somatosensory system property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0001064 name: ventral pancreatic duct namespace: uberon alt_id: UBERON:0005627 def: "A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla." [Wikipedia:Pancreatic_duct] subset: human_reference_atlas subset: uberon_slim synonym: "canal of Wirsung" RELATED [BTO:0002362] synonym: "chief pancreatic duct" EXACT [FMA:16003] synonym: "duct of Wirsung" EXACT [Wikipedia:Pancreatic_duct] synonym: "ductus pancreatis ventralis" RELATED [] synonym: "hepaticopancreatic duct" RELATED [BTO:0002362] synonym: "main pancreatic duct" EXACT [MA:0000126] synonym: "pancreatic duct" BROAD [MESH:A03.734.667] xref: BTO:0002362 xref: EHDAA2:0001396 xref: EHDAA:6905 xref: EMAPA:17510 xref: FMA:16003 xref: GAID:337 xref: MA:0000126 xref: MESH:D010183 xref: NCIT:C12272 xref: RETIRED_EHDAA2:0002177 xref: SCTID:245385001 xref: UMLS:C0030288 {source="ncithesaurus:Pancreatic_Duct"} xref: VHOG:0000256 xref: Wikipedia:Pancreatic_duct is_a: UBERON:0000025 ! tube is_a: UBERON:0007329 {source="FMA"} ! pancreatic duct relationship: channel_for UBERON:0001970 ! bile relationship: channels_into UBERON:0004913 ! hepatopancreatic ampulla relationship: continuous_with UBERON:0001174 ! common bile duct relationship: develops_from UBERON:0003924 {source="EHDAA2"} ! ventral pancreatic bud property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png" xsd:anyURI property_value: editor_note "in EHDAA2 this is an epithelium, in FMA the wall consists of epithelium and connective tissue" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000256", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS, Lorent K, Pack M, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "Upon reaching its final destination, the ventral pancreatic bud fuses with the much larger dorsal pancreatic bud. At this point of fusion, the main ducts of the ventral and dorsal pancreatic buds fuse, forming the duct of Wirsung, the main pancreatic duct." xsd:string {source="WP"} [Term] id: UBERON:0001067 name: vertebral arch joint namespace: uberon def: "A synovial joint between the prezygapophysis of one vertebra and the postzygapophysis of the vertebra directly above it. There are two facet joints in each spinal motion segment[WP]." [Wikipedia:Zygapophysial_joint] subset: pheno_slim subset: uberon_slim synonym: "articulationes zygapophysiales" RELATED LATIN [Wikipedia:Zygapophysial_joint] synonym: "facet joint" EXACT [] synonym: "joint of vertebral arch" EXACT [] synonym: "joint of vertebral articular process" EXACT [] synonym: "spinal facet joint" EXACT [HP:0008482] synonym: "zygapophyseal joint" EXACT [] synonym: "zygapophysial joint" EXACT [] xref: FMA:10447 xref: GAID:275 xref: MA:0001513 xref: MESH:D021801 xref: NCIT:C32577 xref: SCTID:89836005 xref: UMLS:C0224521 {source="ncithesaurus:Facet_Joint"} xref: Wikipedia:Zygapophysial_joint is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002217 ! synovial joint intersection_of: UBERON:0002217 ! synovial joint intersection_of: connects UBERON:0001079 ! prezygapophysis intersection_of: connects UBERON:0001080 ! postzygapophysis relationship: connects UBERON:0001079 ! prezygapophysis relationship: connects UBERON:0001080 ! postzygapophysis relationship: part_of UBERON:0003861 ! neural arch property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray90.png" xsd:anyURI [Term] id: UBERON:0001068 name: skin of back namespace: uberon def: "A zone of skin that is part of a back [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "back skin" EXACT [] synonym: "back zone of skin" EXACT [OBOL:automatic] synonym: "skin, dorsal region" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "zone of skin of back" EXACT [OBOL:automatic] xref: EMAPA:36392 xref: FMA:10462 xref: FMA:22985 xref: MA:0000498 xref: SCTID:181492002 is_a: UBERON:0001085 {source="MA"} ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0011270 {source="MA"} ! dorsal trunk property_value: editor_note "TODO - distinguish between entire skin of region and arbitrary zone of skin on region" xsd:string [Term] id: UBERON:0001070 name: external carotid artery namespace: uberon def: "A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]." [MGI:anna] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arteria carotis externa" RELATED LATIN [Wikipedia:External_carotid_artery] synonym: "external carotid" EXACT [AAO:0010218] xref: AAO:0010218 xref: AAO:0010416 xref: BTO:0004696 xref: EFO:0001953 xref: EHDAA2:0000461 xref: EMAPA:18611 xref: FMA:10635 xref: GAID:480 xref: MA:0001929 xref: MESH:D002342 xref: NCIT:C32551 xref: SCTID:362044002 xref: UMLS:C0007275 {source="ncithesaurus:External_Carotid_Artery"} xref: VHOG:0000265 xref: Wikipedia:External_carotid_artery xref: XAO:0000345 is_a: UBERON:0005396 {source="MA"} ! carotid artery segment relationship: branching_part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches relationship: develops_from UBERON:0001530 {source="EHDAA2"} ! common carotid artery plus branches relationship: part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/13/External_carotid_a.gif" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://sourceforge.net/tracker/?func=detail&aid=3486863&group_id=76834&atid=1127722" xsd:anyURI property_value: UBPROP:0000008 "not homologous to the external carotid of zebrafish (Goodrich, 1958) - http://zfish.nichd.nih.gov/zfatlas/Intro%20Page/comparative.html; check XAO" xsd:string [Term] id: UBERON:0001071 name: superficial cervical artery namespace: uberon def: "It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery." [Wikipedia:Superficial_part_of_transverse_cervical_artery] comment: The transverse cervical artery splits into two branches, a superficial one and a deep one[WP] subset: human_reference_atlas subset: uberon_slim synonym: "superficial branch of transverse cervical artery" EXACT [Wikipedia:Superficial_part_of_transverse_cervical_artery] xref: EMAPA:37117 {source="MA:th"} xref: FMA:10665 xref: MA:0002052 xref: NCIT:C53005 xref: SCTID:161746006 xref: UMLS:C0226271 {source="ncithesaurus:Superficial_Cervical_Artery"} xref: Wikipedia:Superficial_part_of_transverse_cervical_artery is_a: UBERON:0012320 ! cervical artery intersection_of: UBERON:0012320 ! cervical artery intersection_of: part_of UBERON:0035549 ! vasculature of integument relationship: connected_to UBERON:0012324 ! transverse cervical artery relationship: part_of UBERON:0035549 ! vasculature of integument property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001072 name: posterior vena cava namespace: uberon def: "A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Inferior_vena_cava] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "caudal vena cava" RELATED [VHOG:0001194] synonym: "inferior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "inferior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "postcava" RELATED [] synonym: "posterior vena cava" EXACT [Wikipedia:Venae_cavae] synonym: "vena cava inferior" RELATED LATIN [BTO:0002682, Wikipedia:Inferior_vena_cava] xref: AAO:0011083 xref: BTO:0002682 xref: EHDAA2:0000611 xref: EMAPA:18416 xref: FMA:10951 xref: GAID:548 xref: galen:InferiorVenaCava xref: MA:0000480 xref: MESH:D014682 xref: NCIT:C12815 xref: SCTID:181369003 xref: UMLS:C0042458 {source="ncithesaurus:Inferior_Vena_Cava"} xref: VHOG:0001194 xref: Wikipedia:Inferior_vena_cava xref: XAO:0000388 is_a: UBERON:0004087 ! vena cava intersection_of: UBERON:0004087 ! vena cava intersection_of: drains UBERON:0000154 ! posterior region of body disjoint_from: UBERON:0001585 {source="lexical"} ! anterior vena cava relationship: channels_into UBERON:0002078 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! right cardiac atrium relationship: connected_to UBERON:0002078 ! right cardiac atrium relationship: develops_from UBERON:0005487 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia:Vitelline_vein"} ! vitelline vein relationship: drains UBERON:0000154 ! posterior region of body relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4d/Gray577.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Trunk of systemic vein which is formed by the union of the right common iliac vein and the left common iliac vein and terminates in the right atrium[FMA]." xsd:string {source="FMA:10951"} property_value: UBPROP:0000003 "Phylogenetic modifications within this basic pattern of arteries and veins are largely correlated with functional changes. In the transition from water to land, gills gave way to lungs, accompanied by the establishment of a pulmonary circulation. In some fishes and certainly in tetrapods, the cardinal veins become less involved in blood return. Instead, the composite, prominent postcava (posterior vena cava) arose to drain the posterior part of the body and the precava (anterior vena cava) developed to drain the anterior part of the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001194", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.454-455", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001073 name: ileocecal junction namespace: uberon def: "A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice." [http://www.medilexicon.com/medicaldictionary.php?t=46539] synonym: "ileocaecal junction" EXACT [] xref: EMAPA:37601 {source="MA:th"} xref: FMA:11338 xref: MA:0000332 xref: SCTID:264021000 is_a: UBERON:8410024 ! intestinal junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000059 ! large intestine intersection_of: connects UBERON:0002108 ! small intestine relationship: connects UBERON:0000059 ! large intestine relationship: connects UBERON:0002108 ! small intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: UBERON:0001074 name: pericardial cavity namespace: uberon def: "A potential space between the visceral and parietal layers of the pericardium." [Wikipedia:Pericardium] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cavitas pericardiaca" RELATED LATIN [Wikipedia:Pericardial_cavity] synonym: "cavity of pericardial sac" EXACT [] synonym: "pericardial space" EXACT [Wikipedia:Pericardial_cavity] xref: BSA:0000091 xref: EHDAA2:0001434 xref: EMAPA:16131 xref: EMAPA:16132 xref: FMA:11350 xref: galen:PericardialSpace xref: MA:0000053 xref: NCIT:C38662 xref: SCTID:362027001 xref: TAO:0002220 xref: UMLS:C0225972 {source="ncithesaurus:Pericardial_Cavity"} xref: VHOG:0000556 xref: Wikipedia:Pericardial_cavity xref: ZFA:0001655 is_a: UBERON:0002323 {source="MA"} ! coelemic cavity lumen is_a: UBERON:0035809 ! serous cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002406 ! pericardial sac relationship: contains UBERON:0002409 ! pericardial fluid relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom relationship: luminal_space_of UBERON:0002406 ! pericardial sac relationship: part_of UBERON:0002406 {source="FMA"} ! pericardial sac relationship: surrounded_by UBERON:0002357 ! serous pericardium property_value: RO:0002175 NCBITaxon:7718 {source="PMID:20959416"} property_value: UBPROP:0000001 "Anatomical space in which the heart is located and is surrounded by the pericardium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002220", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart (of other tetrapods) is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000556", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "check ZFA, should actually be thoracic cavity. Note that Hyman defines the cavity as the space between the heart and the sac (but defines the sac as parietal)" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0001075 name: bony vertebral centrum namespace: uberon def: "Ossified form of a vertebral centrum, a skeletal element that functionally replaces the notochord[VSAP,modified]." [http://orcid.org/0000-0002-6601-2165, VSAO:0000183, VSAO:curator] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arcocentrum" NARROW INCONSISTENT [PMID:11746457] synonym: "autocentrum" NARROW [PMID:11746457, ZFA:0000126] synonym: "body of vertebra" EXACT [FMA:11945] synonym: "centra" RELATED PLURAL [PHENOSCAPE:ad] synonym: "corpus vertebra" EXACT LATIN [] synonym: "corpus vertebrae" RELATED PLURAL [Wikipedia:Body_of_vertebra] synonym: "corpus vertebrae (vertebrale)" EXACT [FMA:11945] synonym: "holocentrum" NARROW [PMID:11746457] synonym: "vertebral body" EXACT [FMA:11945] synonym: "vertebral centra" RELATED PLURAL [PHENOSCAPE:ad] synonym: "vertebral centrum" RELATED [MA:0001457] xref: AAO:0000697 xref: EMAPA:36588 xref: FMA:11945 xref: MA:0001457 xref: NCIT:C12852 xref: SCTID:361745008 xref: SCTID:362867001 xref: TAO:0000126 xref: UMLS:C0223084 {source="ncithesaurus:Vertebral_Body"} xref: Wikipedia:Body_of_vertebra xref: ZFA:0000126 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0016491 ! vertebral centrum element intersection_of: UBERON:0016491 ! vertebral centrum element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: part_of UBERON:0002412 ! vertebra property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/63/Corpusvertebrae.png" xsd:anyURI property_value: UBPROP:0000001 "Centra are represented by mineralized, calcified, or ossified portions that surround the notochord. The autocentrum, present in Danio and all other living teleosts, is formed by direct ossification outside the elastica externa of the notochord (Arratia, 1999).[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000126", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Cylindrical body of bone, round or oval in cross section, which functionally replaces the notochord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000697", ontology="AAO", source="AAO:Duellman_and_Trueb_2008"} property_value: UBPROP:0000001 "The body is the largest part of a vertebra, and is more or less cylindrical in shape. Its upper and lower surfaces are flattened and rough, and give attachment to the intervertebral fibrocartilages, and each presents a rim around its circumference. In front, the body is convex from side to side and concave from above downward. Behind, it is flat from above downward and slightly concave from side to side. Its anterior surface presents a few small apertures, for the passage of nutrient vessels. On the posterior surface is a single large, irregular aperture, or occasionally more than one, for the exit of the basi-vertebral veins from the body of the vertebra. [WP,unvetted][Wikipedia:Body_of_vertebra]." xsd:string {source="Wikipedia:Body_of_vertebra"} property_value: UBPROP:0000005 "The vertebral centrum may be cartilaginous, develop as cartilage but be replaced by bone or mineralized, or form directly through intramembranous ossification.[VSAO]" xsd:string {date_retrieved="2012-09-06", external_class="VSAO:0000183", ontology="VSAO", source="Curator"} property_value: UBPROP:0000012 "VSAO definition states it surrounds notochord but not applicable to post-natal." xsd:string {external_ontology="VSAO"} [Term] id: UBERON:0001076 name: neural spine namespace: uberon def: "An extension of a neural arches dorsal to the neural canal[TAO,modified]." [http://orcid.org/0000-0002-6601-2165, TAO:0001336] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "neural spine" RELATED [] synonym: "neural spines" RELATED PLURAL [ZFA:0001336] synonym: "processus spinosus" EXACT [] synonym: "processus spinosus vertebrae" EXACT [] synonym: "spine of verterba" RELATED [FMA:11948] synonym: "spinous process" BROAD [] synonym: "spinous process of vertebra" EXACT HUMAN_PREFERRED [FMA:11948] synonym: "vertebra spinous process" EXACT [MA:0001455] xref: AAO:0000705 xref: EMAPA:25107 xref: FMA:11948 xref: MA:0001455 xref: NCIT:C116112 xref: SCTID:264259004 xref: TAO:0001336 xref: Wikipedia:Spinous_process xref: ZFA:0001336 is_a: UBERON:0006061 ! process of vertebra relationship: part_of UBERON:0003861 ! neural arch property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/48/Processusspinosusvertebrae.png" xsd:anyURI property_value: UBPROP:0000001 "Elaboration of the mid-dorsal keel into a posterior or posterolateral process.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000705", ontology="AAO", source="AAO:Pugener_and_Maglia_2008"} property_value: UBPROP:0000001 "Neural spines are extensions of neural arches dorsal to the neural canal in the median skeletogenous septum. Neural spines are typically unpaired median structures but can be paired in some instances, e.g., in the abdominal region of basal teleosts such as Leptolepis, Elops, Megalops, and Hiodon).[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001336", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Small, posteriorly directed process at the posterior margin of each neural arch lamina; it is not a neural spine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000739", ontology="AAO", source="AAO:Pugener_2002"} property_value: UBPROP:0000002 "relationship loss: part_of mid-dorsal keel (AAO:0000735)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000705", ontology="AAO"} property_value: UBPROP:0000008 "The spinous process of a vertebra is directed backward and downward from the junction of the laminae (in humans), and serves for the attachment of muscles and ligaments. In animals without an erect stance, the process points upward and may slant forward or backward. Spinous processes are exaggerated in some animals, such as the extinct Dimetrodon and Spinosaurus, where they form a sail- or finback. [Wikipedia:Spinous_process]" xsd:string [Term] id: UBERON:0001077 name: transverse process of vertebra namespace: uberon def: "The transverse or costal processes of a vertebra, two in number, project one at either side from the point where the lamina joins the pedicle, between the superior and inferior articular processes. They serve for the attachment of muscles and ligaments. [WP,unvetted]." [Wikipedia:Transverse_process] subset: pheno_slim subset: uberon_slim synonym: "diapophyses" RELATED [] synonym: "diapophysis" RELATED [] synonym: "processus transversus" EXACT [] synonym: "processus transversus vertebrae" EXACT [] synonym: "transverse process" EXACT [] synonym: "vertebra transverse process" EXACT [] xref: AAO:0000698 xref: FMA:11949 xref: MA:0001456 xref: SCTID:264238006 xref: Wikipedia:Transverse_process xref: XAO:0003102 is_a: UBERON:0006061 ! process of vertebra property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a1/Processustransversusvertebrae.PNG" xsd:anyURI property_value: UBPROP:0000001 "Projections on each side of the vertebra from the point where the neural arch lamina joins the pedicel for the articulation with the head of a single-headed rib or the upper head of a double-headed rib. Also called diapophyses. They provide surfaces for the attachment of muscles. In anurans, the term transverse process is used in reference to the processes associated with the presacral and postsacral vertebrae." xsd:string {source="AAO:0000698"} [Term] id: UBERON:0001079 name: prezygapophysis namespace: uberon def: "Paired processes at the cephalic end of the neural arch. The articular facets of the prezygapophyses face dorsomedially and articulate with the lateroventrally facing facets of the postzygapophyses of the preceding vertebra." [AAO:Pugener_and_Maglia_2008] subset: vertebrate_core synonym: "cranial articular process of vertebra" EXACT [] synonym: "neural prezygapophyses" RELATED PLURAL [TAO:0001325] synonym: "neural prezygapophysis" NARROW DUBIOUS [ZFA:0001325] synonym: "neural prezygopophyses" NARROW DUBIOUS [ZFA:0001325] synonym: "prezygapophysis" EXACT [] synonym: "processus articularis superior" EXACT [] synonym: "processus articularis superior vertebrae" EXACT LATIN [FMA:11953, FMA:TA] synonym: "superior articular process of vertebra" EXACT HUMAN_PREFERRED [FMA:11953] synonym: "vertebra cranial articular process" EXACT [] synonym: "zygapophysis superior" EXACT LATIN [FMA:11953, FMA:TA] xref: AAO:0000703 xref: EMAPA:37802 {source="MA:th"} xref: FMA:11953 xref: http://www.informatics.jax.org/cookbook/figures/figure20.shtml xref: MA:0001452 xref: SCTID:42424006 xref: TAO:0001325 xref: ZFA:0001325 is_a: UBERON:0006062 ! zygapophysis property_value: editor_note "TODO - add distinct classes for hemal vs neural?" xsd:string property_value: UBPROP:0000001 "Paired, anteromedially directed processes from the neural arches, ligamentously joined to the postzygapophyses of the preceding vertebra.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001325", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001080 name: postzygapophysis namespace: uberon def: "Paired processes at the caudal end of the neural arch. The articular facets of the postzygapophyses face lateroventrally and articulate with the dorsomedially facing facets of the prezygapophyses of the succeeding vertebra." [AAO:LAP] comment: Posteriorly projecting processes allowing de facto contact between consecutive vertebrae (some soft tissues are also present) via articular facets. [PHENOSCAPE:NI] subset: pheno_slim subset: vertebrate_core synonym: "caudal articular process of vertebra" EXACT [] synonym: "inferior articular process of vertebra" EXACT HUMAN_PREFERRED [FMA:11954] synonym: "neural postzygapophyses" RELATED PLURAL [TAO:0000681] synonym: "neural postzygapophysis" NARROW DUBIOUS [ZFA:0000681] synonym: "neural postzygopophyses" RELATED [TAO:0000681] synonym: "neural postzygopophysis" EXACT [ZFA:0000681] synonym: "postzygapophysis" EXACT [] synonym: "processus articularis inferior" EXACT [] synonym: "processus articularis inferior vertebrae" EXACT LATIN [FMA:11954, FMA:TA] synonym: "processus obliquus posterior" RELATED [AAO:0000702] synonym: "vertebra caudal articular process" EXACT [] synonym: "zygapophysis inferior" EXACT LATIN [FMA:11954, FMA:TA] xref: AAO:0000702 xref: EMAPA:35918 xref: FMA:11954 xref: MA:0001451 xref: SCTID:30079000 xref: TAO:0000681 xref: ZFA:0000681 is_a: UBERON:0006062 ! zygapophysis property_value: UBPROP:0000001 "Paired, dorsomedially directed processes on the posterior ends of the centra, ligamentously joined to the neural prezygapophyses of the immediately posterior vertebra.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000681", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001081 name: endocardium of ventricle namespace: uberon def: "Endocardium that is part of the cardiac ventricle." [ZFIN:curator] subset: pheno_slim subset: vertebrate_core synonym: "cardiac ventricle endocardium" EXACT [OBOL:automatic] synonym: "endocardium of cardiac ventricle" EXACT [OBOL:automatic] synonym: "endocardium of heart ventricle" EXACT [OBOL:automatic] synonym: "endocardium of lower chamber of heart" EXACT [OBOL:automatic] synonym: "endocardium of ventricle of heart" EXACT [OBOL:automatic] synonym: "heart ventricle endocardium" EXACT [OBOL:automatic] synonym: "lower chamber of heart endocardium" EXACT [OBOL:automatic] synonym: "ventricle endocardial tissue" RELATED [VHOG:0000607] synonym: "ventricle endocardium" EXACT [] synonym: "ventricle of heart endocardium" EXACT [OBOL:automatic] synonym: "ventricular endocardium" EXACT [] xref: EMAPA:32747 xref: FMA:12148 xref: MA:0000079 xref: SCTID:192172004 xref: TAO:0002247 xref: VHOG:0000607 xref: ZFA:0001615 is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0002165 ! endocardium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: contributes_to_morphology_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! heart ventricle wall [Term] id: UBERON:0001082 name: epicardium of ventricle namespace: uberon def: "An epicardial layer that lines a cardiac ventricle." [http://orcid.org/0000-0002-6601-2165] subset: vertebrate_core synonym: "cardiac ventricle epicardium" EXACT [OBOL:automatic] synonym: "ventricular epicardium" EXACT [] xref: FMA:12150 xref: TAO:0005058 xref: ZFA:0005058 is_a: UBERON:0002348 ! epicardium intersection_of: UBERON:0002348 ! epicardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle property_value: UBPROP:0000001 "The external layer of the ventricle bounding the ventricular myocardium. It is formed by a single layer of mesothelial cells supported by a basal lamina, and imbricated with collagen, fibroblasts, and vascular structures in the subepicardial space. Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005058", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001083 name: myocardium of ventricle namespace: uberon def: "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer." [ZFIN:curator] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "ventricle cardiac muscle" RELATED [VHOG:0000604] synonym: "ventricle myocardium" EXACT [] synonym: "ventricular myocardium" EXACT [] xref: EFO:0003088 xref: EMAPA:32748 xref: FMA:12151 xref: MA:0000082 xref: SCTID:192084000 xref: TAO:0005061 xref: VHOG:0000604 xref: ZFA:0005061 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: contributes_to_morphology_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0004784 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! heart ventricle wall property_value: UBPROP:0000001 "Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005061", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000604", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001084 name: skin of head namespace: uberon def: "A zone of skin that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head zone of skin" EXACT [OBOL:automatic] synonym: "head skin" EXACT [] synonym: "head zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of adult head" EXACT [OBOL:automatic] synonym: "zone of skin of head" EXACT [OBOL:automatic] xref: FMA:12166 xref: FMA:24756 xref: MA:0000582 xref: NCIT:C52757 xref: SCTID:181484006 xref: UMLS:C0205029 {source="ncithesaurus:Head_Skin"} is_a: UBERON:0012180 ! head or neck skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head property_value: editor_note "TODO - distinguish between entire skin of region and arbitrary zone of skin on region" xsd:string [Term] id: UBERON:0001085 name: skin of trunk namespace: uberon def: "A zone of skin that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "torso zone of skin" EXACT [OBOL:automatic] synonym: "trunk skin" EXACT [] synonym: "trunk zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of torso" EXACT [OBOL:automatic] synonym: "zone of skin of trunk" EXACT [OBOL:automatic] xref: EMAPA:37278 {source="MA:th"} xref: FMA:12167 xref: FMA:23093 xref: MA:0000517 xref: NCIT:C12295 xref: SCTID:181489001 xref: UMLS:C0205031 {source="ncithesaurus:Skin_of_the_Trunk"} is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk property_value: editor_note "TODO - distinguish between entire skin of region and arbitrary zone of skin on region" xsd:string [Term] id: UBERON:0001087 name: pleural fluid namespace: uberon def: "Transudate contained in the pleural cavity." [FMA:12273] subset: uberon_slim xref: BTO:0003080 xref: FMA:12273 xref: MA:0002532 xref: MAT:0000500 xref: ncithesaurus:Pleural_Fluid xref: Wikipedia:Pleural_fluid is_a: UBERON:0036244 ! secretion of serous membrane intersection_of: UBERON:0007779 ! transudate intersection_of: located_in UBERON:0002402 ! pleural cavity relationship: located_in UBERON:0002402 ! pleural cavity [Term] id: UBERON:0001088 name: urine namespace: uberon def: "Excretion that is the output of a kidney." [https://github.com/geneontology/go-ontology/issues/11025, Wikipedia:Urine] subset: efo_slim subset: pheno_slim subset: uberon_slim xref: BTO:0001419 xref: CALOHA:TS-1092 xref: EFO:0001939 xref: EMAPA:36554 xref: ENVO:00002047 xref: FMA:12274 xref: GAID:1189 xref: galen:Urine xref: MA:0002545 xref: MAT:0000058 xref: MESH:D014556 xref: MIAA:0000058 xref: NCIT:C13283 xref: UMLS:C0042036 {source="ncithesaurus:Urine"} xref: Wikipedia:Urine is_a: UBERON:0000174 ! excreta intersection_of: UBERON:0000174 ! excreta intersection_of: produced_by UBERON:0002113 ! kidney relationship: has_quality PATO:0001548 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! quality of a liquid relationship: produced_by UBERON:0002113 ! kidney property_value: UBPROP:0000008 "kidney excreta from some taxa (e.g. in aves) may not be liquid" xsd:string [Term] id: UBERON:0001090 name: synovial fluid namespace: uberon def: "Joint fluid is a transudate of plasma that is actively secreted by synovial cells." [https://www.ncbi.nlm.nih.gov/books/NBK274/] subset: uberon_slim subset: vertebrate_core synonym: "joint fluid" EXACT [https://www.ncbi.nlm.nih.gov/books/NBK274/] xref: BTO:0001339 xref: CALOHA:TS-0996 xref: ENVO:02000039 xref: FMA:12277 xref: GAID:265 xref: galen:SynovialFluid xref: MA:0002544 xref: MESH:D013582 xref: NCIT:C33718 xref: TAO:0005154 xref: UMLS:C0039097 {source="ncithesaurus:Synovial_Fluid"} xref: Wikipedia:Synovial_fluid xref: ZFA:0005154 is_a: UBERON:0007779 ! transudate is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland intersection_of: UBERON:0007779 ! transudate intersection_of: produced_by CL:0000214 ! synovial cell relationship: has_part CHEBI:16336 ! hyaluronic acid relationship: located_in UBERON:0007617 ! synovial cavity of joint relationship: produced_by CL:0000214 ! synovial cell property_value: UBPROP:0000001 "Portion of organism substance that is a clear fluid that occupies the space in synovial joints.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005154", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000009 "It provides nutrients and lubrication for articular cartilage" xsd:string property_value: UBPROP:0000010 "The fluid contains hyaluronan secreted by fibroblast-like cells in the synovial membrane, lubricin (proteoglycan 4; PRG4) secreted by the surface chondrocytes of the articular cartilage and interstitial fluid filtered from the blood plasma" xsd:string [Term] id: UBERON:0001091 name: calcareous tooth namespace: uberon def: "Skeletal element within the mouth (or in some species, upper part of the digestive tract) that is composed of dentine and is used in procuring or masticating food." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Tooth_(animal)] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "dental element" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "dentine containing tooth" EXACT [] synonym: "tooth" EXACT [] synonym: "vertebrate tooth" EXACT [] xref: AEO:0000220 xref: BTO:0000397 xref: CALOHA:TS-1055 xref: EFO:0000839 xref: EHDAA2:0004605 xref: EMAPA:32906 xref: EV:0100063 xref: FMA:12516 xref: GAID:1260 xref: MA:0000348 xref: MAT:0000041 xref: MESH:D014070 xref: MIAA:0000041 xref: NCIT:C12506 xref: SCTID:302214001 xref: TAO:0001625 xref: UMLS:C0040426 {source="ncithesaurus:Tooth"} xref: VHOG:0001733 xref: Wikipedia:Tooth xref: XAO:0000431 xref: ZFA:0000694 is_a: UBERON:0003913 ! tooth-like structure is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: develops_from UBERON:0008281 ! tooth bud relationship: has_developmental_contribution_from UBERON:0000930 {source="XAO-modified"} ! stomodeum relationship: has_developmental_contribution_from UBERON:0005176 {source="ZFA-modified"} ! tooth enamel organ relationship: has_part UBERON:0001751 ! dentine relationship: has_part UBERON:0001752 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! enamel relationship: immediate_transformation_of UBERON:0008281 {source="cjm"} ! tooth bud relationship: in_lateral_side_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! jaw region relationship: part_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! jaw region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/14/Teeth_by_David_Shankbone.jpg" xsd:anyURI property_value: editor_note "we place ZFA ctb 5 tooth here for now. Consider changing name from calcaeeous tooth. Note that sea cucumbers develop calcareous tooth-like structures" xsd:string property_value: RO:0002161 NCBITaxon:189497 {source="Wikipedia"} property_value: RO:0002161 NCBITaxon:8782 property_value: RO:0002161 NCBITaxon:9257 {source="PMID:10210685"} property_value: RO:0002161 NCBITaxon:9761 property_value: UBPROP:0000003 "The ancestor of recent vertebrate teeth was a tooth-like structure on the outer body surface of jawless fishes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001733", ontology="VHOG", source="PMID:19266065 Koussoulakou DS, Margaritis LH, Koussoulakos SL, A curriculum vitae of teeth: evolution, generation, regeneration. International Journal of Biological Sciences (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "dental" xsd:string property_value: UBPROP:0000008 "absent in living platypus, present in toothed Miocene platypus Obduron dicksoni" xsd:string {source="PMID:10210685"} [Term] id: UBERON:0001092 name: vertebral bone 1 namespace: uberon def: "The first vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "atlas" EXACT [] synonym: "atlas (CI)" EXACT [] synonym: "atlas [C I]" EXACT LATIN [FMA:12519, FMA:TA] synonym: "atlas vertebra" EXACT [] synonym: "C1" BROAD [] synonym: "C1 vertebra" EXACT [] synonym: "cervical atlas" EXACT [MP:0011576] synonym: "cervical vertebra 1" EXACT HUMAN_PREFERRED [MA:0001421] synonym: "first cervical vertebra" EXACT [] synonym: "vertebra 1" EXACT [TAO:0001167] xref: AAO:0000709 xref: EHDAA:10606 xref: EMAPA:19431 xref: FMA:12519 xref: GAID:236 xref: MA:0001421 xref: MESH:D001270 xref: NCIT:C32239 xref: SCTID:181818007 xref: TAO:0001167 xref: UMLS:C0004170 {source="ncithesaurus:C1_Vertebra"} xref: Wikipedia:Atlas_(anatomy) xref: ZFA:0001167 is_a: UBERON:0002412 ! vertebra relationship: anterior_to UBERON:0001093 ! vertebral bone 2 relationship: anteriorly_connected_to UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! occipital bone relationship: part_of UBERON:0006072 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! cervical region of vertebral column property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "First postcranial vertebra, which is modified anteriorly to articulate with the skull.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000709", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} property_value: UBPROP:0000001 "Vertebra that is posteriorly adjacent to the neurocranium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001167", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000107 "1" xsd:nonNegativeInteger [Term] id: UBERON:0001093 name: vertebral bone 2 namespace: uberon def: "The second vertebral bone in the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "axis" RELATED INCONSISTENT [MA:0001422] synonym: "axis (CII)" EXACT [] synonym: "axis [C II]" EXACT LATIN [FMA:12520, FMA:TA] synonym: "axis vertebra" EXACT [] synonym: "C2" RELATED [] synonym: "C2 vertebra" NARROW [] synonym: "cervical axis" EXACT [MP:0004608] synonym: "cervical vertebra 2" NARROW HUMAN_PREFERRED [MA:0001422] synonym: "second cervical vertebra" NARROW [] synonym: "vertebra 2" EXACT [ZFA:0001168] xref: EHDAA:10608 xref: EMAPA:19432 xref: FMA:12520 xref: GAID:237 xref: MA:0001422 xref: MESH:D001368 xref: NCIT:C32240 xref: SCTID:181819004 xref: TAO:0001168 xref: UMLS:C0004457 {source="ncithesaurus:C2_Vertebra"} xref: Wikipedia:Axis_(anatomy) xref: ZFA:0001168 is_a: UBERON:0002412 ! vertebra relationship: anteriorly_connected_to UBERON:0001092 {source="FMA"} ! vertebral bone 1 relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0006072 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! cervical region of vertebral column property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Vertebra that is posteriorly adjacent to vertebra 1.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001168", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000013 "not the same as ZFA term 'axis'" xsd:string property_value: UBPROP:0000107 "2" xsd:nonNegativeInteger [Term] id: UBERON:0001094 name: sacral vertebra namespace: uberon def: "A vertebra bone that is part of the sacral region of the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "sacral segment" EXACT [] synonym: "segment of sacrum" EXACT [] xref: AAO:0000552 xref: EMAPA:18336 xref: FMA:12526 xref: galen:SacralVertebra xref: MA:0000313 xref: NCIT:C12853 xref: neuronames:1706 xref: SCTID:361773005 xref: UMLS:C1261045 {source="ncithesaurus:Sacral_Vertebra"} xref: Wikipedia:Sacrum xref: XAO:0003078 is_a: UBERON:0002412 ! vertebra is_a: UBERON:0003828 ! abdominal segment bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0015010 ! sacral vertebra endochondral element intersection_of: UBERON:0015010 ! sacral vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010745 ! sacral vertebra cartilage element property_value: editor_note "todo - AAO placement to be confirmed by AAO curators (the AAO class may also include modified ribs)" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Enlarged vertebra with transverse processes (diapophyses), and ocassionally ribs, that are modified and elaborated for support of the pelvic girdle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000552", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} [Term] id: UBERON:0001095 name: caudal vertebra namespace: uberon alt_id: UBERON:0006070 def: "Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx)." [http://orcid.org/0000-0002-6601-2165] comment: Taxon notes In zebrafish, Vertebra bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "caudal vertebra" BROAD SENSU [FMA:12527] synonym: "caudal vertebrae" EXACT PLURAL [] synonym: "caudal vertebral bone" EXACT [] synonym: "caudal vertebral bone element" EXACT [] synonym: "coccygea" RELATED [MA:0001420] synonym: "coccygeal segment" EXACT [] synonym: "coccygeal vertebra" EXACT [FMA:12527] synonym: "fused tail vertebra" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "tail vertebra" RELATED [MA:0000310] xref: EMAPA:18374 xref: FMA:12527 xref: galen:CoccygealVertebra xref: MA:0000310 xref: MA:0001420 xref: NCIT:C32334 xref: SCTID:361774004 xref: TAO:0000326 xref: UMLS:C0223616 {source="ncithesaurus:Coccygeal_Vertebra"} xref: Wikipedia:Caudal_vertebra xref: XAO:0003079 xref: ZFA:0000326 is_a: UBERON:0002412 ! vertebra is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Vertebrae bearing a hemal arch and spine. The most posterior caudal vertebrae support the caudal fin and are referred to as preural vertebrae.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000326", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000012 "we deliberately merge the MA classes as we believe them equivalent" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001096 name: wall of esophagus namespace: uberon def: "An anatomical wall that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of esophagus" EXACT [OBOL:automatic] synonym: "anatomical wall of gullet" EXACT [OBOL:automatic] synonym: "anatomical wall of oesophagus" EXACT [OBOL:automatic] synonym: "esophageal wall" EXACT [] synonym: "esophagus anatomical wall" EXACT [OBOL:automatic] synonym: "esophagus wall" EXACT [] synonym: "gullet anatomical wall" EXACT [OBOL:automatic] synonym: "gullet wall" EXACT [OBOL:automatic] synonym: "oesophagus anatomical wall" EXACT [OBOL:automatic] synonym: "oesophagus wall" EXACT [OBOL:automatic] synonym: "wall of gullet" EXACT [OBOL:automatic] synonym: "wall of oesophagus" EXACT [OBOL:automatic] xref: EMAPA:35326 xref: FMA:12611 xref: MA:0002691 is_a: UBERON:0000328 ! gut wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0001098 name: incisor tooth namespace: uberon def: "Incisors are the first kind of tooth in heterodont mammals. They are located in the premaxilla above and mandible below. [WP,unvetted]." [https://github.com/obophenotype/uberon/issues/221, Wikipedia:Incisor_tooth] comment: Humans normally have eight (8) incisors; Among other animals, some other primates, cats and horses have twelve. Rodents have four, while Foxes have nine. Rabbits and hares (lagomorphs) were once considered rodents, but are distinguished by having eight - one small pair, called 'peg teeth', is located directly behind the most anterior pair. Incisors are used to bite off tough foods, such as red meat subset: pheno_slim subset: uberon_slim synonym: "incisor" EXACT [MA:0000349] xref: BTO:0001741 xref: EHDAA:8011 xref: EHDAA:8047 xref: EMAPA:32889 xref: FMA:12823 xref: GAID:1263 xref: MA:0000349 xref: MESH:D007180 xref: NCIT:C32769 xref: SCTID:420856006 xref: UMLS:C0021156 {source="ncithesaurus:Incisor"} xref: Wikipedia:Incisor_tooth is_a: UBERON:0001091 ! calcareous tooth disjoint_from: UBERON:0003655 ! molar tooth disjoint_from: UBERON:0003674 ! cuspid disjoint_from: UBERON:0007120 ! premolar tooth relationship: part_of UBERON:0003672 ! dentition property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4c/Gray997.png" xsd:anyURI [Term] id: UBERON:0001103 name: diaphragm namespace: uberon def: "A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control." [MP:0002279] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "diaphragm muscle" EXACT [BTO:0000341] synonym: "diaphragm of thorax" EXACT [] synonym: "midriff" RELATED [BTO:0000341] synonym: "phren" RELATED [BTO:0000341] synonym: "thoracic diaphragm" EXACT [] xref: BTO:0000341 xref: CALOHA:TS-0198 xref: EFO:0000937 xref: EHDAA2:0003495 xref: EMAPA:17701 xref: EV:0100376 xref: FMA:13295 xref: GAID:158 xref: MA:0001904 xref: MAT:0000502 xref: MESH:D003964 xref: NCIT:C12702 xref: SCTID:181614006 xref: UMLS:C0011980 {source="ncithesaurus:Diaphragm"} xref: VHOG:0000713 xref: Wikipedia:Thoracid_diaphragm is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0003830 ! thoracic segment muscle is_a: UBERON:0003831 ! respiratory system muscle relationship: develops_from UBERON:0010084 ! future diaphragm relationship: immediate_transformation_of UBERON:0010084 {evidence="definitional"} ! future diaphragm relationship: innervated_by UBERON:0001884 ! phrenic nerve relationship: only_in_taxon NCBITaxon:40674 {source="PMID:23586979"} ! Mammalia property_value: RO:0002161 NCBITaxon:8782 {source="Wikipedia:Thoracic_diaphragm#Comparative_anatomy_and_evolution"} property_value: UBPROP:0000001 "The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs[GO]." xsd:string {source="GO:0060539"} property_value: UBPROP:0000003 "The mammals are characterized by a diaphragm, which separates the thoracic portion of the body cavity from the abdominal region and assists in drawing air into the lungs and forcing it out. Modern reptiles lack a muscular diaphragm and it is reasonable to suppose that the diaphragm developed as a new device that made possible a large degree of oxygen intake for active animals. The change may have taken place during the transition from reptile to mammal (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000713", ontology="VHOG", source="ISBN:978-0471384618 Colbert EH, Evolution of the vertebrates: a history of the backboned animals through time (2001) p.278", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "phrenic" xsd:string property_value: UBPROP:0000008 "The existence of some membrane separating the pharynx from the stomach can be traced widely among the chordates. Thus amphioxus possesses an atrium by which water exits the pharynx, which has been argued (and disputed) to be homologous to structures in ascidians and hagfishes.[3]" xsd:string property_value: UBPROP:0000008 "The urochordate epicardium separates digestive organs from the pharynx and heart, but the anus returns to the upper compartment to discharge wastes through an outgoing siphon (Thoracic_diaphragm#Comparative_anatomy_and_evolution)" xsd:string property_value: UBPROP:0000009 "barrier between thoracic and abdominal cavities; stop gastric contents from refluxing into the oesophagus" xsd:string property_value: UBPROP:0000009 "breathing control" xsd:string property_value: UBPROP:0000011 "originate from the cervical somites, likely C3-C5[PMID:23586979]" xsd:string [Term] id: UBERON:0001105 name: clavicle bone namespace: uberon def: "A paired dermal or endochondral bone that is part of the pectoral girdle. The clavicle may be in contact with the interclavicle or coracoid and forms an attachment site for pectoral musculature. [PHENOSCAPE:ad]." [https://github.com/obophenotype/uberon/issues/103, PHENOSCAPE:ad] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "clavicle" EXACT [VSAO:0005031] synonym: "clavicula" EXACT [VSAO:0005031] synonym: "collar bone" EXACT [] synonym: "collarbone" EXACT [] xref: AAO:0000761 xref: EMAPA:18721 xref: FMA:13321 xref: GAID:182 xref: galen:Clavicle xref: MA:0001329 xref: MESH:D002968 xref: MFMO:0000047 xref: NCIT:C12695 xref: SCTID:181910004 xref: UMLS:C0008913 {source="ncithesaurus:Clavicle"} xref: VHOG:0000849 xref: VSAO:0005031 xref: Wikipedia:Clavicle is_a: UBERON:0002495 {source="FMA"} ! long bone is_a: UBERON:0003461 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! shoulder bone is_a: UBERON:0007829 ! pectoral girdle bone is_a: UBERON:0015212 ! lateral structure relationship: connected_to UBERON:0000975 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sternum relationship: develops_from UBERON:0010905 {editor="mah", source="ISBN:978-0-12-319060-4"} ! clavicle bone primordium relationship: has_developmental_contribution_from UBERON:0010843 {notes="from secondary cartilage of fusion", source="ISBN:978-0-12-319060-4"} ! clavicle cartilage element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: in_lateral_side_of UBERON:0002091 ! appendicular skeleton relationship: overlaps UBERON:0001469 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! sternoclavicular joint property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/59/Pectoral_girdles-en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Slender, paired bones of intramembranous origin that invest the anterior margins of the procoracoids.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000761", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: part_of zonal element (AAO:0000936)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000761", ontology="AAO"} property_value: UBPROP:0000003 "In early tetrapods, the connecting skull bone, the posttemporal, and adjoining shoulder bones, supracleithrum and postcleithrum (=anocleithrum), are absent, leaving a dermal shoulder girdle composed of the remaining ventral elements: the paired cleithrum and clavicle, and an unpaired midventral interclavicle that joins both halves of the girdle across the midline. (...) Several dermal elements of the shoulder persist in early synapsids. The clavicle and interclavicle are present in therapsids and monotremes, but in marsupials and placentals, the interclavicle is absent, the clavicle often is reduced in size, and the scapula becomes the predominant shoulder element.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000849", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.330-333 and Figure 9.18", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "clavicular" xsd:string property_value: UBPROP:0000008 "The clavicle first appears as part of the skeleton in primitive bony fish, where it is associated with the pectoral fin; they also have a bone called the cleithrum. In such fish, the paired clavicles run behind and below the gills on each side, and are joined by a solid symphysis on the fish's underside. They are, however, absent in cartilagenous fish and in the vast majority of living bony fish, including all of the teleosts[ISBN 0-03-910284-X]." xsd:string property_value: UBPROP:0000011 "In most birds and mammals the clavicles are the only dermal elements in the trunk, and is the only membrane bone associated with the pectoral girdle in these taxa. However, there can be secondary cartilage, or subsequent endochondral ossification, or fusion with endochondral elements. In rodents, the lateral ends of the clavicle are endochondral but the main portion is dermal." xsd:string {source="ISBN:978-0-12-319060-4"} property_value: UBPROP:0000012 "FMA and MA differ in whether they consider this part of the shoulder" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001112 name: latissimus dorsi muscle namespace: uberon def: "The latissimus dorsi is the larger, flat, dorso-lateral muscle on the trunk, posterior to the arm, and partly covered by the trapezius on its median dorsal region. [WP,unvetted]." [Wikipedia:Latissimus_dorsi_muscle] comment: Dorsal group[Kardong] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "dorsal latissimus muscle" EXACT [] synonym: "latissimi dorsi" EXACT PLURAL [] synonym: "latissimus dorsi" EXACT [] synonym: "musculus latissimus dorsi" EXACT [] synonym: "musculus latissimus dorsi" RELATED LATIN [Wikipedia:Latissimus_dorsi_muscle] xref: EFO:0003067 xref: EHDAA2:0000932 xref: EHDAA:8307 xref: EMAPA:18178 xref: FMA:13357 xref: MA:0002331 xref: NCIT:C33150 xref: SCTID:181747008 xref: UMLS:C0224362 {source="ncithesaurus:Musculus_Latissimus_Dorsi"} xref: VHOG:0000930 xref: Wikipedia:Latissimus_dorsi_muscle is_a: UBERON:0001482 ! muscle of shoulder is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0034908 ! scapular muscle relationship: develops_from UBERON:0010982 {source="EHDAA2"} ! latissimus dorsi pre-muscle mass relationship: has_muscle_antagonist UBERON:0001476 {source="dbpedia"} ! deltoid relationship: has_muscle_antagonist UBERON:0002380 {source="dbpedia"} ! trapezius muscle relationship: has_muscle_insertion UBERON:0000976 {notes="floor of intertubercular groove of the humerus", source="dbpedia"} ! humerus relationship: has_muscle_origin UBERON:0006849 ! scapula relationship: has_muscle_origin UBERON:0007175 {notes="spinous processes of thoracic T7-T12 thoracolumbar fascia iliac crest and inferior 3 or 4 ribs inferior angle of scapula", source="dbpedia"} ! inferior angle of scapula relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/7d/Latissimus_dorsi.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In humans it inserts along a roughened line deep in the groove. In other mammals (most, I believe) it is an actual projection, the latissimus dorsi process [FEED:rd] [https://github.com/obophenotype/uberon/issues/1192]" xsd:string [Term] id: UBERON:0001113 name: lobe of liver namespace: uberon def: "Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe." [Wikipedia:Liver#Lobes] synonym: "hepatic lobe" EXACT [] synonym: "liver lobe" EXACT [] synonym: "lobus hepatis" EXACT [] xref: EMAPA:18306 xref: FMA:13361 xref: MA:0000360 xref: NCIT:C49579 xref: SCTID:245378000 xref: UMLS:C0447541 {source="ncithesaurus:Liver_Lobe"} xref: Wikipedia:Liver#Lobes is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0009912 {source="FMA"} ! anatomical lobe relationship: part_of UBERON:0002107 ! liver property_value: editor_note "some work needs to be done to ensure the child terms of this class have correct isa/partof placement. in MA they are subclasses, in FMA they are parts" xsd:string [Term] id: UBERON:0001114 name: right lobe of liver namespace: uberon def: "The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]." [Wikipedia:Right_lobe_of_liver] subset: uberon_slim subset: vertebrate_core synonym: "2nd lobe" RELATED [TAO:0005173] synonym: "gall bladder lobe" RELATED SENSU [ZFA:0005173] synonym: "liver right lobe" EXACT [] synonym: "lobus hepaticus dexter" EXACT LATIN [] synonym: "lobus hepatis dexter" RELATED LATIN [Wikipedia:Right_lobe_of_liver] synonym: "right hepatic lobe" RELATED [EMAPA:18311] synonym: "right liver lobe" EXACT [ZFA:0005173] synonym: "second lobe" RELATED [TAO:0005173] xref: EHDAA2:0001008 xref: EHDAA:4001 xref: EMAPA:18311 xref: FMA:13362 xref: MA:0000363 xref: NCIT:C33481 xref: SCTID:362182008 xref: TAO:0005173 xref: UMLS:C0227481 {source="ncithesaurus:Right_Lobe_of_the_Liver"} xref: VHOG:0001424 xref: Wikipedia:Right_lobe_of_liver xref: ZFA:0005173 is_a: UBERON:0001113 ! lobe of liver property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png" xsd:anyURI property_value: UBPROP:0000001 "Portion of the liver which develops on the fish's right side adjacent to the gall bladder.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005173", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001115 name: left lobe of liver namespace: uberon def: "The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]." [Wikipedia:Left_lobe_of_liver] subset: uberon_slim subset: vertebrate_core synonym: "left hepatic lobe" RELATED [EMAPA:18307] synonym: "left liver lobe" EXACT [] synonym: "liver left lobe" EXACT [] synonym: "lobus hepaticus sinister" EXACT LATIN [] synonym: "lobus hepatis sinister" RELATED LATIN [Wikipedia:Left_lobe_of_liver] xref: EHDAA2:0001000 xref: EHDAA:3995 xref: EMAPA:18307 xref: FMA:13363 xref: MA:0000361 xref: NCIT:C32965 xref: SCTID:362183003 xref: TAO:0005172 xref: UMLS:C0227486 {source="ncithesaurus:Left_Lobe_of_the_Liver"} xref: VHOG:0001423 xref: Wikipedia:Left_lobe_of_liver xref: ZFA:0005172 is_a: UBERON:0001113 ! lobe of liver property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray1087-liver.png" xsd:anyURI property_value: UBPROP:0000001 "Portion of the liver which develops on the fish's left side.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005172", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001125 name: serratus ventralis namespace: uberon def: "The serratus ventralis is a muscle that originates on the surface of the upper eight or nine ribs at the side of the chest and inserts along the entire anterior length of the medial border of the scapula. [WP,unvetted]." [Wikipedia:Serratus_anterior_muscle] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "Boxer's muscle" EXACT [] synonym: "musculus serratus anterior" RELATED LATIN [Wikipedia:Serratus_anterior_muscle] synonym: "serratus anterior" EXACT [VHOG:0000679] synonym: "serratus anterior muscle" EXACT [] synonym: "serratus lateralis" RELATED LATIN [Wikipedia:Serratus_anterior_muscle] synonym: "serratus ventralis muscle" EXACT [] xref: EHDAA2:0001832 xref: EHDAA:9463 xref: EMAPA:18525 xref: FMA:13397 xref: MA:0002378 xref: NCIT:C53014 xref: SCTID:181748003 xref: UMLS:C1710059 {source="ncithesaurus:Serratus_Ventralis"} xref: VHOG:0000679 xref: Wikipedia:Serratus_anterior_muscle is_a: UBERON:0001482 ! muscle of shoulder is_a: UBERON:0034908 ! scapular muscle relationship: develops_from UBERON:0010986 {source="EHDAA2"} ! serratus ventralis pre-muscle mass relationship: has_muscle_antagonist UBERON:0002380 {source="dbpedia"} ! trapezius muscle relationship: has_muscle_insertion UBERON:0006849 {notes="costal aspect of medial margin of the scapula", source="dbpedia"} ! scapula relationship: has_muscle_origin UBERON:0002228 {notes="fleshy slips from the outer surface of upper 8 or 9 ribs", source="dbpedia"} ! rib relationship: innervated_by UBERON:0003726 {notes="long thoracic nerve", source="dbpedia"} ! thoracic nerve property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/c6/Serratus_anterior.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001130 name: vertebral column namespace: uberon def: "Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/?func=detail&aid=3530322&group_id=76834&atid=2257941, VSAO:0000185] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "backbone" NARROW [FMA:13478] synonym: "columna vertebralis" RELATED [BTO:0000818] synonym: "dorsal spine" RELATED [BTO:0000818] synonym: "spinal column" RELATED [MESH:A02.835.232.834] synonym: "spine" BROAD [FMA:13478] synonym: "vertebral column skeleton" NARROW [AAO:0000699] synonym: "vertebral region" RELATED [] xref: AAO:0000699 xref: AAO:0000734 xref: BTO:0000818 xref: EFO:0001369 xref: EHDA:10119 xref: EMAPA:35919 xref: FMA:13478 xref: GAID:106 xref: galen:SpinalColumn xref: MA:0002416 xref: MESH:D013131 xref: NCIT:C12998 xref: NCIT:C33588 xref: NIF_Subcellular:sao1145756102 xref: SCTID:44300000 xref: TAO:0001559 xref: UMLS:C0037949 {source="ncithesaurus:Vertebral_Column"} xref: UMLS:C1519455 {source="ncithesaurus:Spinal_Cord_Column"} xref: VHOG:0001142 xref: VSAO:0000185 xref: Wikipedia:Vertebral_column xref: XAO:0003074 xref: ZFA:0001559 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 ! subdivision of skeletal system intersection_of: UBERON:0000075 ! subdivision of skeletal system intersection_of: composed_primarily_of UBERON:0010913 ! vertebral element relationship: composed_primarily_of UBERON:0010913 ! vertebral element relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0011138 {source="cjm"} ! postcranial axial skeletal system relationship: protects UBERON:0002240 ! spinal cord property_value: editor_note "Note that in contrast to VSAO, this is a subset of the skeletal system, and thus includes intervertebral joints, cartilage and ligaments etc. Some ontologies such as AAO seem to purely refer to the skeleton" xsd:string property_value: RO:0002161 NCBITaxon:7762 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical cluster that consists of all the vertebra in the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000185", ontology="VSAO", source="VSAO:curator"} property_value: UBPROP:0000001 "The vertebral column consists of a series of vertebrae connected by ligaments. It provides a supporting axis for the body and protects the spinal cord. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001142", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/vertebral+column"} property_value: UBPROP:0000003 "Vertebrata is characterized by three synapomorphies. First, vertebrates have a backbone composed of vertebrae (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001142", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.53", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001131 name: vertebral foramen namespace: uberon def: "A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Vertebral_foramen] subset: uberon_slim synonym: "foramen vertebrale" RELATED LATIN [Wikipedia:Vertebral_foramen] synonym: "vertebra neural canal" EXACT [] xref: AAO:0000729 xref: EMAPA:37803 {source="MA:th"} xref: FMA:13479 xref: MA:0001454 xref: SCTID:280734009 xref: Wikipedia:Vertebral_foramen is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: conduit_for UBERON:0002240 ! spinal cord intersection_of: lumen_of UBERON:0010913 ! vertebral element relationship: conduit_for UBERON:0002240 ! spinal cord relationship: lumen_of UBERON:0010913 ! vertebral element relationship: part_of UBERON:0006692 ! vertebral canal relationship: part_of UBERON:0010913 ! vertebral element property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/10/Foramenvertebrale.png" xsd:anyURI property_value: UBPROP:0000001 "Opening on the vertebra for a spinal nerve as it emerges from the spinal canal.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000729", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0001133 name: cardiac muscle tissue namespace: uberon alt_id: UBERON:0007096 def: "Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]." [ZFA:0005280] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cardiac muscle" EXACT [] synonym: "cardiac muscle muscle tissue" EXACT [OBOL:automatic] synonym: "cardiac muscle textus muscularis" EXACT [OBOL:automatic] synonym: "cardiac musculature" RELATED [BILA:0000134] synonym: "heart muscle muscle tissue" EXACT [OBOL:automatic] synonym: "heart muscle textus muscularis" EXACT [OBOL:automatic] synonym: "heart myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "heart myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "muscle of heart muscle tissue" EXACT [OBOL:automatic] synonym: "muscle of heart textus muscularis" EXACT [OBOL:automatic] synonym: "muscle tissue of cardiac muscle" EXACT [OBOL:automatic] synonym: "muscle tissue of heart muscle" EXACT [OBOL:automatic] synonym: "muscle tissue of heart myocardium" EXACT [OBOL:automatic] synonym: "muscle tissue of muscle of heart" EXACT [OBOL:automatic] synonym: "muscle tissue of myocardium" EXACT [OBOL:automatic] synonym: "myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "textus muscularis of cardiac muscle" EXACT [OBOL:automatic] synonym: "textus muscularis of heart muscle" EXACT [OBOL:automatic] synonym: "textus muscularis of heart myocardium" EXACT [OBOL:automatic] synonym: "textus muscularis of muscle of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium" EXACT [OBOL:automatic] xref: AAO:0010245 xref: AEO:0000142 xref: BILA:0000134 xref: BTO:0000199 xref: CALOHA:TS-0440 xref: EHDAA2:0003142 xref: EMAPA:32688 xref: FMA:14068 xref: galen:CardiacMuscle xref: galen:CardiacMuscleTissue xref: ncithesaurus:Heart_Muscle xref: TAO:0005280 xref: Wikipedia:Cardiac_muscle xref: ZFA:0005280 is_a: UBERON:8600006 ! visceral striated muscle tissue intersection_of: UBERON:0002036 ! striated muscle tissue intersection_of: has_part CL:0000746 ! cardiac muscle cell disjoint_from: UBERON:0001134 ! skeletal muscle tissue relationship: composed_primarily_of CL:0000746 ! cardiac muscle cell relationship: has_part CL:0000746 ! cardiac muscle cell relationship: part_of UBERON:0000948 {source="ZFA"} ! heart property_value: editor_note "check relationship with myocardium. part_of in MA - but we also have a more specific class 'cardiac muscle tissue of myocardium'. Check ncit" xsd:string [Term] id: UBERON:0001134 name: skeletal muscle tissue namespace: uberon def: "Muscle tissue that consists primarily of skeletal muscle fibers." [https://github.com/obophenotype/uberon/issues/324] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "skeletal muscle" BROAD [] synonym: "skeletal muscle system" RELATED [BTO:0001103] synonym: "somatic muscle" RELATED [BTO:0001103] xref: EMAPA:32716 xref: FMA:14069 xref: MA:0002439 xref: NCIT:C13050 xref: SCTID:426215008 xref: UMLS:C0242692 {source="ncithesaurus:Skeletal_Muscle_Tissue"} xref: Wikipedia:Skeletal_striated_muscle is_a: UBERON:0002036 ! striated muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: composed_primarily_of CL:0008002 ! skeletal muscle fiber relationship: composed_primarily_of CL:0008002 ! skeletal muscle fiber relationship: develops_from UBERON:0003082 ! myotome relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/dosumis relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/RDruzinsky relationship: part_of UBERON:0014892 ! skeletal muscle organ property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/c0/Skeletal_muscle.jpg" xsd:anyURI property_value: editor_note "TODO - add skeletal muscle organ? See GO:0060538 skeletal muscle organ development. Todo - group FBbt:00005073 - somatic muscle." xsd:string property_value: UBPROP:0000001 "Muscle, composed of long cylindrical, multinucleated cells that attaches to the skeleton via tendons.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005277", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Tissue which consists of skeletal muscle fibers surrounded by endomysium. Examples: Skeletal muscle tissue of biceps, Skeletal muscle tissue of diaphragm[FMA]" xsd:string {external_class="FMA:14069", ontology="FMA"} property_value: UBPROP:0000003 "This result implies the following views in terms of evolutionary differentiation: (1) Arthropod striated muscle and vertebrate skeletal and cardiac muscles share a common ancestor. In other words, they did not evolve independently (...) (5) The divergence of vertebrate skeletal and cardiac muscles/vertebrate smooth muscle and nonmuscle is at least before that of vertebrates/arthropods. In other words, emergence of skeletal and cardiac musle type tissues preceded the vertebrate/arthropod divergence (ca. 700 MYA).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000319", ontology="VHOG", source="PMID:10368962 Oota S, Saitou N, Phylogenetic relationship of muscle tissues deduced from superimposition of gene trees. Mol Biol Evol (1999)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001135 name: smooth muscle tissue namespace: uberon def: "Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]." [GO:0006939, Wikipedia:Smooth_muscle_tissue] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "involuntary muscle" EXACT [] synonym: "non-striated muscle" EXACT [] synonym: "smooth muscle" EXACT [] synonym: "textus muscularis levis; textus muscularis nonstriatus" RELATED LATIN [Wikipedia:Smooth_muscle_tissue] synonym: "textus muscularis nonstriatus" EXACT LATIN [FMA:14070, FMA:TA] synonym: "visceral muscle" NARROW SENSU [] synonym: "visceral muscle tissue" NARROW SENSU [] xref: AAO:0010244 xref: AEO:0000141 xref: BTO:0001260 xref: CALOHA:TS-0943 xref: EFO:0000889 xref: EHDAA2:0003141 xref: EMAPA:32717 xref: EV:0100378 xref: FMA:14070 xref: GAID:167 xref: galen:SmoothMuscle xref: galen:SmoothMuscleTissue xref: MA:0000166 xref: MAT:0000303 xref: MESH:D009130 xref: MIAA:0000303 xref: NCIT:C12437 xref: TAO:0005274 xref: UMLS:C1267092 {source="ncithesaurus:Smooth_Muscle_Tissue"} xref: VHOG:0001246 xref: WBbt:0005781 xref: Wikipedia:Smooth_muscle_tissue xref: XAO:0000175 xref: ZFA:0005274 is_a: UBERON:0002385 ! muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: has_part CL:0000192 ! smooth muscle cell disjoint_from: UBERON:0002036 ! striated muscle tissue relationship: composed_primarily_of CL:0000192 ! smooth muscle cell relationship: has_part CL:0000192 ! smooth muscle cell relationship: has_part GO:0071953 ! elastic fiber property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/3b/Glatte_Muskelzellen.jpg" xsd:anyURI property_value: UBPROP:0000001 "A non-striated muscle that is composed of spindle-shaped cells. Smooth muscle usually is organized into sheets that line cavitated organs.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005274", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Involuntary muscle tissue consisting of uninucleate spindle-shaped fibers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010244", ontology="AAO", source="AAO:CAM"} property_value: UBPROP:0000003 "(...) the first bilateral animals possessed only smooth muscles with the molecular repertoire necessary to build a striated muscle. (...) it is more parsimonious to regard striated muscle cells as a sister cell type to the smooth muscle cells. In this scenario, striated and smooth muscles would have arisen in the stem lineage that led to the Nephrozoa (i.e. all Bilateria exclusive the acoelomorphs) (Hejnol et al., 2009), from an 'acoel-like' smooth muscle, by segregation and divergence of functions and through differential recruitment of additional genes[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001246", ontology="VHOG", source="DOI:10.1002/jez.b.21416 Chiodin M, Achatz JG, Wanninger A, Martinez P, Molecular architecture of muscles in an acoel and its evolutionary implications. Journal of Experimental Zoology (2011)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "GO uses visceral and smooth interchangeably. However visceral can also be used in the sense of the viscera. Many fly annotations to smooth muscle terms. If we want to be inclusive of insects have to have a general definition of tissue that includes cells." xsd:string [Term] id: UBERON:0001136 name: mesothelium namespace: uberon def: "Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri)." [FMA:14074, Wikipedia:Mesothelium] subset: uberon_slim xref: AEO:0000111 xref: BTO:0002422 xref: CALOHA:TS-1183 xref: EHDAA2_RETIRED:0003111 xref: EHDAA:2331 xref: EHDAA:2349 xref: EHDAA:295 xref: EHDAA:6073 xref: EHDAA:640 xref: EHDAA:646 xref: EMAPA:32856 xref: FMA:14074 xref: MA:0000565 xref: NCIT:C33105 xref: SCTID:361918002 xref: UMLS:C0086610 {source="ncithesaurus:Mesothelium"} xref: Wikipedia:Mesothelium is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000487 ! simple squamous epithelium intersection_of: develops_from UBERON:0000926 ! mesoderm intersection_of: part_of UBERON:0000042 ! serous membrane relationship: composed_primarily_of CL:0000077 {source="FMA"} ! mesothelial cell relationship: part_of UBERON:0000042 ! serous membrane property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/25/Mesothelium_peritoneal_wash_high_mag.jpg" xsd:anyURI [Term] id: UBERON:0001137 name: dorsum namespace: uberon def: "A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.." [BSPO:0000063, UBERONREF:0000006, Wikipedia:Dorsum_(anatomy)] subset: efo_slim subset: uberon_slim synonym: "back" EXACT [FMA:14181] synonym: "back of body proper" EXACT [FMA:14181] synonym: "dorsal part of organism" EXACT [] xref: BTO:0001713 xref: CALOHA:TS-2223 xref: EFO:0001405 xref: FMA:14181 xref: GAID:30 xref: galen:Back xref: MESH:D001415 xref: NCIT:C13062 xref: SCTID:123961009 xref: UMLS:C0004600 {source="ncithesaurus:Back"} xref: Wikipedia:Dorsum_(anatomy) is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/432px-Gray-back.PNG" xsd:anyURI property_value: UBPROP:0000007 "dorsal" xsd:string property_value: UBPROP:0000008 "In humans, called the back, a large posterior area of the human body, rising from the top of the buttocks to the back of the neck and the shoulders. It is the surface opposite to the chest, its height being defined by the vertebral column (commonly referred to as the spine or backbone) and its breadth being supported by the ribcage and shoulders. The spinal canal runs through the spine and provides nerves to the rest of the body" xsd:string [Term] id: UBERON:0001138 name: superior mesenteric vein namespace: uberon def: "In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Superior_mesenteric_vein] subset: human_reference_atlas subset: uberon_slim synonym: "upper mesenteric vein" RELATED [BTO:0002783] synonym: "vena mesenterica superior" RELATED LATIN [Wikipedia:Superior_mesenteric_vein] xref: BTO:0002783 xref: EHDAA2:0001951 xref: EHDAA:5414 xref: EMAPA:18643 xref: FMA:14332 xref: MA:0002179 xref: NCIT:C33687 xref: SCTID:278031001 xref: UMLS:C0226742 {source="ncithesaurus:Superior_Mesenteric_Vein"} xref: VHOG:0000552 xref: Wikipedia:Superior_mesenteric_vein is_a: UBERON:0005617 ! mesenteric vein intersection_of: UBERON:0005617 ! mesenteric vein intersection_of: drains UBERON:0002108 ! small intestine relationship: connected_to UBERON:0001639 ! hepatic portal vein relationship: develops_from UBERON:0005487 {source="Wikipedia:Vitelline_vein"} ! vitelline vein relationship: drains UBERON:0002108 ! small intestine relationship: part_of UBERON:0005806 ! portal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001139 name: common iliac vein namespace: uberon def: "A vein that drains the pelvis and lower limbs into the inferior vena cava." [MURDOCH:403, Wikipedia:Common_iliac_vein] subset: human_reference_atlas subset: uberon_slim synonym: "common iliac venous tree" EXACT [] synonym: "vena iliaca communis" RELATED LATIN [Wikipedia:Common_iliac_vein] xref: EMAPA:17874 xref: FMA:14333 xref: galen:CommonIliacVein xref: MA:0002143 xref: NCIT:C32359 xref: SCTID:181398004 xref: UMLS:C0226758 {source="ncithesaurus:Common_Iliac_Vein"} xref: Wikipedia:Common_iliac_vein is_a: UBERON:0005610 {source="MA"} ! iliac vein is_a: UBERON:0015212 ! lateral structure relationship: in_lateral_side_of UBERON:0001072 {source="FMA-abduced-lr"} ! posterior vena cava relationship: part_of UBERON:0001072 ! posterior vena cava property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/65/Iliac_veins.gif" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In human anatomy, the common iliac veins are formed by the external iliac veins and internal iliac veins and together, in the abdomen at the level of the fifth lumbar vertebrae, form the inferior vena cava. They drain blood from the pelvis and lower limbs. Both common iliac veins are accompanied along their course by common iliac arteries." xsd:string {source="Wikipedia:Common_iliac_vein"} [Term] id: UBERON:0001140 name: renal vein namespace: uberon def: "Either of the pair of major vessels which arise from the renal hilus and return blood from the kidneys, suprarenal gland and the ureter to the inferior vena cava." [ISBN:0-683-40008-8, MGI:csmith, MP:0011323] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "kidney vein" EXACT [OBOL:automatic] synonym: "renal venous tree" EXACT [] synonym: "vein of kidney" EXACT [OBOL:automatic] synonym: "venae renales" RELATED LATIN [Wikipedia:Renal_vein] xref: BTO:0002681 xref: EHDAA2:0001602 xref: EHDAA:8722 xref: EMAPA:28376 xref: FMA:14334 xref: GAID:544 xref: galen:RenalVein xref: MA:0002210 xref: MESH:D012082 xref: NCIT:C33462 xref: SCTID:116358006 xref: UMLS:C0035092 {source="ncithesaurus:Renal_Vein"} xref: Wikipedia:Renal_vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002113 ! kidney relationship: drains UBERON:0002113 ! kidney relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0001072 ! posterior vena cava property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1122.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The renal veins are veins that drain the kidney. They connect the kidney to the inferior vena cava. It is usually singular to each kidney, except in the condition 'multiple renal veins'. It also divides into 2 divisions upon entering the kidney: the anterior branch which receives blood from the anterior portion of the kidney and, the posterior branch which receives blood from the posterior portion. Often, each renal vein will have a branch that receives blood from the ureter. [WP,unvetted][Wikipedia:Renal_vein]." xsd:string {source="Wikipedia:Renal_vein"} property_value: UBPROP:0000012 "in EHDAA2, the renal vein is part of the kidney" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0001141 name: right renal vein namespace: uberon def: "A renal vein that drains the right kidney." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim xref: EMAPA:37381 {source="MA:th"} xref: FMA:14335 xref: MA:0002212 xref: NCIT:C52695 xref: SCTID:116357001 xref: UMLS:C0508000 {source="ncithesaurus:Right_Renal_Vein"} is_a: UBERON:0001140 ! renal vein intersection_of: UBERON:0001140 ! renal vein intersection_of: drains UBERON:0004539 ! right kidney relationship: drains UBERON:0004539 ! right kidney property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A vein that drains blood from the right kidney into the inferior vena cava[ncithesaurus]." xsd:string {source="ncithesaurus:Right_Renal_Vein"} [Term] id: UBERON:0001142 name: left renal vein namespace: uberon def: "A renal vein that drains the left kidney." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim xref: EMAPA:37166 {source="MA:th"} xref: FMA:14336 xref: MA:0002211 xref: NCIT:C52693 xref: SCTID:116356005 xref: UMLS:C0508001 {source="ncithesaurus:Left_Renal_Vein"} is_a: UBERON:0001140 ! renal vein intersection_of: UBERON:0001140 ! renal vein intersection_of: drains UBERON:0004538 ! left kidney relationship: drains UBERON:0004538 ! left kidney property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/76/Gray1122.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A vein that drains blood from the left kidney into the inferior vena cava[ncithesaurus]." xsd:string {source="ncithesaurus:Left_Renal_Vein"} [Term] id: UBERON:0001143 name: hepatic vein namespace: uberon def: "Vein that carries blood away from the liver[ZFA]." [https://sourceforge.net/tracker/?func=detail&aid=3565355&group_id=76834&atid=1205376, Wikipedia:Hepatic_vein, ZFA:0000670] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "hepatic veins" RELATED PLURAL [] synonym: "liver vein" EXACT [OBOL:automatic] synonym: "vein of liver" EXACT [OBOL:automatic] synonym: "vena hepatica" EXACT LATIN [] synonym: "venae hepaticae" RELATED LATIN [Wikipedia:Hepatic_vein] xref: AAO:0010216 xref: EMAPA:19221 xref: FMA:14337 xref: GAID:534 xref: galen:HepaticVein xref: MA:0003015 xref: MESH:D006503 xref: NCIT:C32736 xref: SCTID:278191001 xref: TAO:0000670 xref: UMLS:C0019155 {source="ncithesaurus:Hepatic_Vein"} xref: Wikipedia:Hepatic_vein xref: XAO:0000387 xref: ZFA:0000670 is_a: UBERON:0013126 ! vein of abdomen is_a: UBERON:0015796 ! liver blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002107 ! liver disjoint_from: UBERON:0001639 ! hepatic portal vein relationship: develops_from UBERON:0005487 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia:Vitelline_vein"} ! vitelline vein relationship: drains UBERON:0002107 ! liver relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0006877 ! vasculature of liver relationship: tributary_of UBERON:0001072 {source="FMA-abduced-lr"} ! posterior vena cava property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/61/Gray1121.png" xsd:anyURI property_value: editor_note "todo - add developmental relationships for other taxa" xsd:string [Term] id: UBERON:0001144 name: testicular vein namespace: uberon def: "A vein that carries deoxygenated blood from a single male gonad. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis." [http://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/?func=detail&aid=3220553&group_id=76834&atid=1205376, Wikipedia:Testicular_vein] subset: uberon_slim synonym: "male gonadal vein" EXACT [Wikipedia:Testicular_vein] synonym: "spermatic vein" EXACT [Wikipedia:Testicular_vein] synonym: "testicle vein" EXACT [OBOL:automatic] synonym: "testicular venous tree" EXACT [Wikipedia:Testicular_vein] synonym: "vein of testicle" EXACT [OBOL:automatic] synonym: "vena tesicularis" RELATED [BTO:0002678] synonym: "vena testicularis dextra" RELATED LATIN [Wikipedia:Testicular_vein] synonym: "vena testicularis sinistra" RELATED LATIN [Wikipedia:Testicular_vein] synonym: "venae spermaticae" RELATED LATIN [Wikipedia:Testicular_vein] xref: BTO:0002678 xref: EMAPA:18647 xref: FMA:14344 xref: MA:0002218 xref: MA:0002234 xref: NCIT:C53050 xref: SCTID:264496006 xref: UMLS:C0226718 {source="ncithesaurus:Spermatic_Vein"} xref: Wikipedia:Testicular_vein is_a: UBERON:0001638 ! vein is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0000473 ! testis relationship: connected_to UBERON:0001072 ! posterior vena cava relationship: connected_to UBERON:0001330 ! pampiniform plexus relationship: drains UBERON:0000473 ! testis relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism relationship: part_of RO:0002577 ! system relationship: sexually_homologous_to UBERON:0001145 ! ovarian vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1b/Gray590.png" xsd:anyURI property_value: editor_note "TODO - check testicular vs spermatic vein (MA:0002218)" xsd:string property_value: UBPROP:0000008 "In humans, the right testicular vein generally joins the inferior vena cava; the left testicular vein, unlike the right, often joins the left renal vein instead of the inferior vena cava. The veins emerge from the back of the testis, and receive tributaries from the epididymis; they unite and form a convoluted plexus, called the pampiniform plexus, which constitutes the greater mass of the spermatic cord; the vessels composing this plexus are very numerous, and ascend along the cord, in front of the ductus deferens. Below the subcutaneous inguinal ring, they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins, which ascend on the Psoas major, behind the peritoneum, lying one on either side of the internal spermatic artery. These unite to form a single vein, which opens, on the right side, into the inferior vena cava (at an acute angle), on the left side into the left renal vein (at a right angle). The spermatic veins are provided with valves. The left spermatic vein passes behind the iliac colon and is thus exposed to pressure from the contents of that part of the bowel" xsd:string [Term] id: UBERON:0001145 name: ovarian vein namespace: uberon def: "A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries." [Wikipedia:Ovarian_vein] subset: uberon_slim synonym: "female reproductive system gonad vein" EXACT [OBOL:automatic] synonym: "female reproductive system gonada vein" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system vein" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system vein" EXACT [OBOL:automatic] synonym: "ovary vein" EXACT [OBOL:automatic] synonym: "vein of female reproductive system gonad" EXACT [OBOL:automatic] synonym: "vein of female reproductive system gonada" EXACT [OBOL:automatic] synonym: "vein of gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "vein of gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "vein of ovary" EXACT [OBOL:automatic] synonym: "vena ovarica dextra" RELATED LATIN [Wikipedia:Ovarian_vein] synonym: "vena ovarica sinistra" RELATED LATIN [Wikipedia:Ovarian_vein] xref: EMAPA:18644 xref: FMA:14346 xref: MA:0002186 xref: NCIT:C53058 xref: SCTID:278193003 xref: UMLS:C0226720 {source="ncithesaurus:Ovarian_Vein"} xref: Wikipedia:Ovarian_vein is_a: UBERON:0001638 ! vein is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0000992 ! ovary relationship: drains UBERON:0000992 ! ovary relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/cf/Ovarschaf.jpg" xsd:anyURI [Term] id: UBERON:0001152 name: cystic duct namespace: uberon def: "The tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct." [ISBN:0-683-40008-8, MP:0009493] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "ductus cysticus" RELATED LATIN [Wikipedia:Cystic_duct] xref: EHDAA2:0000333 xref: EHDAA:3045 xref: EMAPA:16841 xref: FMA:14539 xref: GAID:290 xref: galen:CysticDuct xref: MA:0000355 xref: MESH:D003549 xref: NCIT:C32421 xref: SCTID:245398005 xref: TAO:0005166 xref: UMLS:C0010672 {source="ncithesaurus:Cystic_Duct"} xref: VHOG:0000213 xref: Wikipedia:Cystic_duct xref: ZFA:0005166 is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct intersection_of: UBERON:0000058 ! duct intersection_of: continuous_with UBERON:0001174 ! common bile duct intersection_of: continuous_with UBERON:0002110 ! gallbladder disjoint_from: UBERON:0005171 ! hepatic duct relationship: channels_into UBERON:0001174 ! common bile duct relationship: continuous_with UBERON:0001174 ! common bile duct relationship: continuous_with UBERON:0002110 ! gallbladder relationship: develops_from UBERON:0005604 {source="EHDAA2"} ! extrahepatic part of hepatic duct property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI property_value: UBPROP:0000001 "Duct that connects the gall bladder and the common bile duct.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005166", ontology="TAO", source="ZFIN:Curator"} property_value: UBPROP:0000001 "The duct of the gallbladder which joins the common hepatic duct, thus forming the common biliary duct. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000213", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001155 name: colon namespace: uberon def: "A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal." [http://orcid.org/0000-0002-2825-0621, http://orcid.org/0000-0002-6601-2165, Wikipedia:Colon_(anatomy), ZFIN:curator] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "hindgut" RELATED [] synonym: "large bowel" EXACT [] synonym: "posterior intestine" NARROW [] xref: AAO:0010400 xref: BTO:0000269 xref: CALOHA:TS-0158 xref: EFO:0000361 xref: EMAPA:18939 xref: EV:0100079 xref: FMA:14543 xref: GAID:309 xref: galen:Colon xref: MA:0000335 xref: MAP:0000001 xref: MAT:0000526 xref: MESH:D003106 xref: NCIT:C12382 xref: SCTID:302508007 xref: TAO:0000706 xref: UMLS:C0009368 {source="ncithesaurus:Colon"} xref: VHOG:0000648 xref: Wikipedia:Colon_(anatomy) xref: XAO:0000243 xref: ZFA:0000706 is_a: UBERON:0004921 {order="3", source="cjm"} ! subdivision of digestive tract relationship: contributes_to_morphology_of UBERON:0000059 ! large intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000059 {source="FMA"} ! large intestine property_value: editor_note "Some references do not consider the caecum to be part of the colon." xsd:string {xref="http://orcid.org/0000-0002-1572-1316"} property_value: editor_note "TODO - abstract this such that it legitimately covers all vertebrates" xsd:string property_value: UBPROP:0000001 "The last portion of the digestive system, it extracts water and salt from solid wastes before they are eliminated from the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010400", ontology="AAO", source="UBERON:0001155"} property_value: UBPROP:0000001 "The posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates. Wallace et al, 2005.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000706", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000648", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "colonic" xsd:string property_value: UBPROP:0000008 "In mammals, the colon consists of four sections: the ascending colon, the transverse colon, the descending colon, and the sigmoid colon[WP]" xsd:string property_value: UBPROP:0000008 "In zebrafish, the posterior intestine has short longitudinally arranged epithelial folds which are similar to the colon of higher vertebrates[ZFIN]" xsd:string property_value: UBPROP:0000009 "it extracts water and salt from solid wastes before they are eliminated from the body[WP]" xsd:string [Term] id: UBERON:0001159 name: sigmoid colon namespace: uberon def: "The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity." [Wikipedia:Sigmoid_colon] subset: efo_slim subset: human_reference_atlas subset: uberon_slim synonym: "colon sigmoideum" RELATED LATIN [Wikipedia:Sigmoid_colon] synonym: "pelvic colon" RELATED [] synonym: "sigmoid colon" RELATED [] synonym: "sigmoid flexure" RELATED [] xref: BTO:0000645 xref: CALOHA:TS-2044 xref: EFO:0000846 xref: EMAPA:36391 xref: FMA:14548 xref: galen:SigmoidColon xref: MAT:0000314 xref: MESH:D012809 xref: MIAA:0000314 xref: NCIT:C12384 xref: NCIT:C33550 xref: SCTID:362166007 xref: UMLS:C0227391 {source="ncithesaurus:Sigmoid_Colon"} xref: UMLS:C0682612 {source="ncithesaurus:Sigmoid_Flexure"} xref: Wikipedia:Sigmoid_colon is_a: UBERON:0000168 {source="FMA"} ! proximal-distal subdivision of colon relationship: continuous_with UBERON:0001052 ! rectum relationship: develops_from UBERON:0001046 {source="Wikipedia"} ! hindgut property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3b/Dickdarm-Schema.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001161 name: body of stomach namespace: uberon def: "The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]." [GO:0014845, Wikipedia:Body_of_stomach] subset: uberon_slim synonym: "corpus gastricum" RELATED LATIN [BTO:0000505, Wikipedia:Body_of_stomach] synonym: "corpus gastricum (ventriculare)" EXACT [] synonym: "corpus ventriculare" RELATED [BTO:0000505] synonym: "corpus ventriculi" RELATED [BTO:0000505] synonym: "gastric body" EXACT [] synonym: "gastric corpus" RELATED [] synonym: "stomach body" EXACT [] xref: BTO:0000505 xref: EMAPA:35810 xref: FMA:14560 xref: galen:GastricCorpus xref: MA:0002559 xref: NCIT:C12258 xref: SCTID:362140009 xref: UMLS:C0227230 {source="ncithesaurus:Body_of_Stomach"} xref: Wikipedia:Body_of_stomach is_a: UBERON:0009870 {source="FMA"} ! zone of stomach property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI property_value: editor_note "we include this as zone of stomach even though it is not distinguished by gland type" xsd:string [Term] id: UBERON:0001165 name: pyloric antrum namespace: uberon def: "The area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells." [ISBN:0-683-40008-8, MP:0010790] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "antrum" BROAD [] synonym: "antrum of stomach" EXACT [] synonym: "antrum of Willis" RELATED [BTO:0001732] synonym: "antrum pylori" RELATED [BTO:0001732] synonym: "antrum pyloricum" RELATED LATIN [BTO:0001732, Wikipedia:Pyloric_antrum] synonym: "gastric antrum" RELATED [BTO:0001732] synonym: "stomach antrum" RELATED [] synonym: "stomach pyloric antrum" EXACT [] xref: BTO:0001732 xref: EFO:0002555 xref: EMAPA:17891 xref: FMA:14579 xref: GAID:332 xref: galen:PyloricAntrum xref: MA:0001624 xref: MESH:D011706 xref: NCIT:C12259 xref: SCTID:362142001 xref: UMLS:C0034193 {source="ncithesaurus:Antrum_Pylori"} xref: Wikipedia:Pyloric_antrum is_a: UBERON:0009870 {source="FMA"} ! zone of stomach relationship: continuous_with UBERON:0001161 ! body of stomach relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus relationship: has_part CL:0000502 ! type D enteroendocrine cell relationship: has_part CL:0000508 ! type G enteroendocrine cell relationship: part_of UBERON:0001166 {source="Wikipedia"} ! pylorus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI [Term] id: UBERON:0001166 name: pylorus namespace: uberon def: "The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum." [MGI:csmith, MP:0010785] subset: pheno_slim subset: uberon_slim synonym: "pars pylorica" EXACT LATIN [] synonym: "pars pylorica gastricae" EXACT LATIN [FMA:14581, FMA:TA] synonym: "pyloric part of stomach" EXACT [] synonym: "pyloric region" EXACT [] synonym: "stomach pyloric region" EXACT [EHDAA2:0001580] synonym: "valvula pylori" RELATED LATIN [Wikipedia:Pylorus] xref: BTO:0001146 xref: EHDAA2:0001580 xref: EHDAA:4860 xref: EMAPA:17631 xref: FMA:14581 xref: GAID:333 xref: galen:Pylorus xref: MA:0002560 xref: MESH:D011708 xref: NCIT:C12260 xref: SCTID:362143006 xref: UMLS:C0034196 {source="ncithesaurus:Pylorus"} xref: VHOG:0000420 xref: Wikipedia:Pylorus is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0009870 ! zone of stomach intersection_of: UBERON:0009870 ! zone of stomach intersection_of: has_part UBERON:0001165 ! pyloric antrum intersection_of: has_part UBERON:0008858 ! pyloric canal intersection_of: has_part UBERON:0008861 ! pyloric gastric gland relationship: contributes_to_morphology_of UBERON:0000945 ! stomach relationship: has_part UBERON:0001165 ! pyloric antrum relationship: has_part UBERON:0008858 ! pyloric canal relationship: has_part UBERON:0008861 ! pyloric gastric gland property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/31/Gray1046.svg" xsd:anyURI property_value: editor_note "We follow Kardong in defining stomach regions by glands" xsd:string property_value: UBPROP:0000001 "The orifice which allows the passage from the stomach into the intestine. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000420", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000420", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "pyloric" xsd:string [Term] id: UBERON:0001167 name: wall of stomach namespace: uberon def: "The layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between." [MGI:csmith, MP:0010783] subset: pheno_slim synonym: "anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "gastric wall" EXACT [] synonym: "stomach anatomical wall" EXACT [OBOL:automatic] synonym: "stomach wall" EXACT [] synonym: "ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "ventriculus wall" EXACT [OBOL:automatic] synonym: "wall of ventriculus" EXACT [OBOL:automatic] xref: EMAPA:35826 xref: FMA:14582 xref: galen:WallOfStomach xref: MA:0002692 xref: SCTID:279995000 is_a: UBERON:0000328 ! gut wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000945 ! stomach relationship: contributes_to_morphology_of UBERON:0000945 ! stomach relationship: part_of UBERON:0000945 ! stomach [Term] id: UBERON:0001168 name: wall of small intestine namespace: uberon def: "An anatomical wall that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of small bowel" EXACT [OBOL:automatic] synonym: "anatomical wall of small intestine" EXACT [OBOL:automatic] synonym: "small bowel anatomical wall" EXACT [OBOL:automatic] synonym: "small bowel wall" EXACT [OBOL:automatic] synonym: "small intestinal wall" EXACT [] synonym: "small intestine anatomical wall" EXACT [OBOL:automatic] synonym: "small intestine wall" EXACT [] synonym: "wall of small bowel" EXACT [OBOL:automatic] xref: EMAPA:35785 xref: FMA:14615 xref: MA:0002696 xref: NCIT:C33573 xref: UMLS:C1519375 {source="ncithesaurus:Small_Intestinal_Wall_Tissue"} is_a: UBERON:0001262 ! wall of intestine intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0002108 ! small intestine [Term] id: UBERON:0001169 name: wall of large intestine namespace: uberon def: "An anatomical wall that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of large intestine" EXACT [OBOL:automatic] synonym: "large intestinal wall" EXACT [] synonym: "large intestine anatomical wall" EXACT [OBOL:automatic] synonym: "large intestine wall" EXACT [] xref: EMAPA:35470 xref: FMA:14619 xref: MA:0002695 is_a: UBERON:0001262 ! wall of intestine intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0000059 ! large intestine [Term] id: UBERON:0001170 name: mesentery of small intestine namespace: uberon def: "The peritoneum responsible for connecting the jejunum and ileum (parts of the small intestine) to the back wall of the abdomen. Between the two sheets of peritoneum are blood vessels, lymph vessels, and nerves. This allows these parts of the small intestine to move relatively freely within the abdominopelvic cavity. The brain, however, cannot map sensation accurately, so sensation is usually referred to the midline, an example of referred pain[WP]." [Wikipedia:Mesentery#Mesentery_.28proper.29] synonym: "mesentery (proper)" EXACT [Wikipedia:Mesentery] synonym: "mesentery proper" EXACT [FMA:14643] synonym: "small intestinal mesentery" EXACT [FMA:14643] synonym: "small intestine mesentery" EXACT [OBOL:automatic] xref: EMAPA:37745 {source="MA:th"} xref: FMA:14643 xref: MA:0001555 xref: SCTID:245456008 xref: Wikipedia:Mesentery#Mesentery_.28proper.29 is_a: UBERON:0001206 ! serosa of small intestine is_a: UBERON:0004854 ! gastrointestinal system mesentery is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0002108 ! small intestine [Term] id: UBERON:0001171 name: portal lobule namespace: uberon def: "The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel." [MP:0008992] subset: pheno_slim xref: FMA:14653 xref: MA:0002498 xref: NCIT:C33341 xref: UMLS:C0682620 {source="ncithesaurus:Portal_Lobule"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0009911 {source="FMA"} ! lobule relationship: contributes_to_morphology_of UBERON:0001280 ! liver parenchyma relationship: part_of UBERON:0001280 {source="MA", source="MP"} ! liver parenchyma [Term] id: UBERON:0001172 name: hepatic acinus namespace: uberon def: "The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids." [http://orcid.org/0000-0002-6601-2165, http://www.vivo.colostate.edu/hbooks/pathphys/digestion/liver/histo_acinus.html] synonym: "liver acinus" EXACT [] synonym: "portal acinus" EXACT [] xref: EMAPA:35497 xref: FMA:14654 xref: MA:0002496 xref: NCIT:C32992 xref: SCTID:272214009 xref: UMLS:C0227519 {source="ncithesaurus:Liver_Acinus"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0011858 ! acinus of exocrine gland relationship: overlaps UBERON:0001171 ! portal lobule relationship: overlaps UBERON:0004647 ! liver lobule relationship: part_of UBERON:0001280 {source="cjm"} ! liver parenchyma [Term] id: UBERON:0001173 name: biliary tree namespace: uberon def: "A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder." [DOI:10.1002/ar.20664] comment: The path in many species is as follows: Bile canaliculi -> Canals of Hering (intralobar bile duct) -> interlobular bile ducts -> intrahepatic bile ducts -> left and right hepatic ducts merge to form -> common hepatic duct *exits liver* and joins -> cystic duct (from gall bladder) forming -> common bile duct -> joins with pancreatic duct -> forming ampulla of Vater -> enters duodenum [WP] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "biliary tract" RELATED [MA:0001273] xref: AAO:0011020 xref: EMAPA:35172 xref: FMA:14665 xref: SCTID:181267003 xref: UMLS:C0005423 {source="ncithesaurus:Biliary_Tract"} xref: Wikipedia:Biliary_tract xref: XAO:0000455 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0000062 ! organ intersection_of: composed_primarily_of UBERON:0002394 ! bile duct intersection_of: part_of UBERON:0002294 ! biliary system relationship: composed_primarily_of UBERON:0002394 ! bile duct relationship: contributes_to_morphology_of UBERON:0002423 ! hepatobiliary system relationship: develops_from UBERON:0004912 ! biliary bud relationship: has_part UBERON:0001246 ! interlobular bile duct relationship: has_part UBERON:0001282 ! intralobular bile duct relationship: has_part UBERON:0003703 ! extrahepatic bile duct relationship: part_of UBERON:0002294 ! biliary system property_value: RO:0002171 UBERON:0002110 property_value: UBPROP:0000001 "Hollow tree organ, the organ parts of which consist of the bile ducts.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011020", ontology="AAO", source="UBERON:0001173"} [Term] id: UBERON:0001174 name: common bile duct namespace: uberon def: "The part of the biliary tree formed by the union of the cystic duct and the common hepatic duct." [MGI:csmith, MP:0009495] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "ductus choledochus" RELATED LATIN [Wikipedia:Common_bile_duct] synonym: "ductus choledochus (biliaris)" EXACT [] xref: EHDAA2:0000303 xref: EHDAA:3981 xref: EMAPA:17201 xref: FMA:14667 xref: GAID:282 xref: galen:CommonBileDuct xref: MA:0001631 xref: MESH:D003135 xref: NCIT:C12698 xref: SCTID:362199009 xref: TAO:0005165 xref: UMLS:C0009437 {source="ncithesaurus:Common_Bile_Duct"} xref: VHOG:0000214 xref: Wikipedia:Common_bile_duct xref: ZFA:0005165 is_a: UBERON:0003703 ! extrahepatic bile duct relationship: channels_into UBERON:0001064 ! ventral pancreatic duct relationship: continuous_with UBERON:0001152 ! cystic duct relationship: continuous_with UBERON:0001175 ! common hepatic duct property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Digestive system duct that collects bile from the hepatic bile duct and the cystic duct.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005165", ontology="TAO", source="ZFIN:Curator"} property_value: UBPROP:0000001 "The duct formed by the union of the common hepatic and cystic ducts. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000214", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001175 name: common hepatic duct namespace: uberon def: "Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]." [Wikipedia:Common_hepatic_duct, ZFIN:curator] subset: pheno_slim subset: uberon_slim synonym: "ductus hepaticus communis" RELATED LATIN [Wikipedia:Common_hepatic_duct] synonym: "hepatic duct" RELATED [] xref: EMAPA:19101 xref: FMA:14668 xref: GAID:286 xref: MA:0002660 xref: MESH:D006500 xref: NCIT:C32356 xref: SCTID:245403006 xref: UMLS:C0019149 {source="ncithesaurus:Common_Hepatic_Duct"} xref: VHOG:0000220 xref: Wikipedia:Common_hepatic_duct is_a: UBERON:0003703 {source="FMA"} ! extrahepatic bile duct relationship: channels_into UBERON:0001174 ! common bile duct relationship: continuous_with UBERON:0001176 {source="Wikipedia"} ! right hepatic duct relationship: continuous_with UBERON:0001177 {source="Wikipedia"} ! left hepatic duct relationship: develops_from UBERON:0010081 ! future common hepatic duct relationship: immediate_transformation_of UBERON:0010081 {evidence="definitional"} ! future common hepatic duct relationship: part_of UBERON:0005604 {source="MA"} ! extrahepatic part of hepatic duct property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/48/Illu_liver_gallbladder.jpg" xsd:anyURI property_value: editor_note "TODO - MA distinguishes between bile duct, hepatic duct, common bile duct and common hepatic duct. in FMA hepatic duct and common hepatic duct are the same. Common is part of extra-hepatic part" xsd:string property_value: UBPROP:0000001 "The duct which conveys the bile from the liver and unites with the cystic duct to form the common bile duct. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000220", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001176 name: right hepatic duct namespace: uberon def: "The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26034] synonym: "ductus hepaticus dexter" RELATED LATIN [] xref: EHDAA2:0001727 xref: EHDAA:3992 xref: EMAPA:32797 xref: FMA:14669 xref: MA:0001639 xref: NCIT:C33476 xref: SCTID:245401008 xref: UMLS:C0227557 {source="ncithesaurus:Right_Hepatic_Duct"} xref: VHOG:0000217 is_a: UBERON:0003703 ! extrahepatic bile duct intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: continuous_with UBERON:0001114 ! right lobe of liver relationship: continuous_with UBERON:0001114 ! right lobe of liver relationship: part_of UBERON:0005171 ! hepatic duct property_value: UBPROP:0000001 "The duct which drains bile from the right half of the liver and unites with the left hepatic duct to form the common hepatic duct. [adapted_from_http://www.medterms.com/script/main/art.asp?articlekey=26032][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000217", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001177 name: left hepatic duct namespace: uberon def: "The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct." [http://www.medterms.com/script/main/art.asp?articlekey=26035] synonym: "ductus hepaticus sinister" RELATED LATIN [] xref: EHDAA2:0000941 xref: EHDAA:3990 xref: EMAPA:32795 xref: FMA:14670 xref: MA:0001638 xref: NCIT:C32960 xref: SCTID:245400009 xref: UMLS:C0227560 {source="ncithesaurus:Left_Hepatic_Duct"} xref: VHOG:0000218 is_a: UBERON:0003703 ! extrahepatic bile duct intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: continuous_with UBERON:0001115 ! left lobe of liver relationship: continuous_with UBERON:0001115 ! left lobe of liver relationship: part_of UBERON:0005171 ! hepatic duct property_value: UBPROP:0000001 "The duct which drains bile from the left half of the liver and unites with the right hepatic duct to form the common hepatic duct. [adapted_from_http://www.medterms.com/script/main/art.asp?articlekey=26032][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000218", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001178 name: visceral peritoneum namespace: uberon def: "The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Peritoneum#Types] subset: uberon_slim subset: vertebrate_core synonym: "visceral serous membrane of peritoneum" EXACT [UBERON:cjm] xref: EMAPA:16592 xref: FMA:14703 xref: SCTID:362702003 xref: TAO:0005132 xref: VHOG:0001528 xref: Wikipedia:Visceral_peritoneum xref: ZFA:0005132 is_a: UBERON:0022350 ! visceral serous membrane intersection_of: UBERON:0022350 ! visceral serous membrane intersection_of: part_of UBERON:0002358 ! peritoneum relationship: part_of UBERON:0002358 ! peritoneum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI [Term] id: UBERON:0001179 name: peritoneal cavity namespace: uberon def: "Anatomical cavity bounded by visceral and parietal peritoneum." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/86, Wikipedia:Peritoneal_cavity] subset: pheno_slim subset: uberon_slim synonym: "cavitas peritonealis" RELATED LATIN [BTO:0001782, Wikipedia:Peritoneal_cavity] synonym: "saccus serosus peritonei" RELATED LATIN [Wikipedia:Peritoneal_cavity] xref: BTO:0001782 xref: EHDAA2:0001446 xref: EMAPA:16138 xref: FMA:14704 xref: GAID:24 xref: MA:0000054 xref: MESH:D010529 xref: NCIT:C12769 xref: SCTID:181616008 xref: UMLS:C1704247 {source="ncithesaurus:Peritoneal_Cavity"} xref: VHOG:0000852 xref: Wikipedia:Peritoneal_cavity is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0035809 ! serous cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: adjacent_to UBERON:0001178 ! visceral peritoneum intersection_of: adjacent_to UBERON:0001366 ! parietal peritoneum intersection_of: luminal_space_of UBERON:0035820 ! peritoneal sac relationship: adjacent_to UBERON:0001178 ! visceral peritoneum relationship: adjacent_to UBERON:0001366 ! parietal peritoneum relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom relationship: luminal_space_of UBERON:0035820 ! peritoneal sac relationship: part_of UBERON:0035820 ! peritoneal sac property_value: UBPROP:0000001 "The potential space between the parietal and visceral layers of the peritoneum, which are normally in contact. The peritoneal cavity is divided into the greater and lesser sac. The greater sac is the peritoneal cavity, and the lesser sac is the omental bursa. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000852", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/peritoneal+cavity"} property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes) Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000852", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001184 name: renal artery namespace: uberon def: "One of two laterally paired arteries that supplies the kidneys. These are large arteries that branch from the dorsal aorta in primitive vertebrates." [ISBN:0073040584, Wikipedia:Renal_artery] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arteria renalis" RELATED LATIN [Wikipedia:Renal_artery] synonym: "renal arterial tree" EXACT [] synonym: "renal arteries" RELATED PLURAL [] xref: AAO:0010223 xref: BTO:0001165 xref: EFO:0002552 xref: EHDAA2:0004100 xref: EHDAA:5321 xref: EHDAA:8594 xref: EMAPA:28373 xref: FMA:14751 xref: GAID:507 xref: galen:RenalArtery xref: MA:0002035 xref: MESH:D012077 xref: NCIT:C12778 xref: RETIRED_EHDAA2:0001600 xref: SCTID:181339005 xref: TAO:0000420 xref: UMLS:C0035065 {source="ncithesaurus:Renal_Artery"} xref: Wikipedia:Renal_artery xref: ZFA:0000420 is_a: UBERON:0012254 ! abdominal aorta artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002113 ! kidney relationship: supplies UBERON:0002113 ! kidney property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI property_value: editor_note "renal arteries vary widely even in humans. Sub-structures should be checked for taxon variability." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Artery which supplies blood via branches to the gonads, oviducts, and kidneys.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010223", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The renal arteries normally arise off the side of the abdominal aorta, immediately below the superior mesenteric artery, and supply the kidneys with blood. Each is directed across the crus of the diaphragm, so as to form nearly a right angle with the aorta. The renal arteries carry a large portion of total blood flow to the kidneys. Up to a third of total cardiac output can pass through the renal arteries to be filtered by the kidneys. The arterial supply of the kidneys is variable and there may be one or more renal arteries supplying each kidney. It is located above the renal vein. It has a radius of approximately 0.25cm, 0.26 cm at the root. The measured mean diameter can differ depending on the imaging method used. For example, the diameter was found to be 5.04 ± 0.74 mm using ultrasound, but 5.68 ± 1.19 mm using angiography. [WP,unvetted].[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Renal_artery"} [Term] id: UBERON:0001185 name: right renal artery namespace: uberon def: "Renal artery that supplies the right kidney." [https://orcid.org/0000-0002-6601-2165] comment: The right [renal artery] passes behind the inferior vena cava, the right renal vein, the head of the pancreas, and the descending part of the duodenum[WP] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "right renal arterial tree" EXACT [] xref: EMAPA:37380 {source="MA:th"} xref: FMA:14752 xref: MA:0002037 xref: NCIT:C52740 xref: SCTID:36800007 xref: UMLS:C0226332 {source="ncithesaurus:Right_Renal_Artery"} is_a: UBERON:0001184 ! renal artery intersection_of: UBERON:0001184 ! renal artery intersection_of: supplies UBERON:0004539 ! right kidney relationship: supplies UBERON:0004539 ! right kidney property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001186 name: left renal artery namespace: uberon def: "Renal artery that supplies the left kidney." [https://orcid.org/0000-0002-6601-2165] comment: The left [renal artery] is somewhat higher than the right; it lies behind the left renal vein, the body of the pancreas and the splenic vein, and is crossed by the inferior mesenteric vein[WP] subset: human_reference_atlas subset: pheno_slim synonym: "left renal arterial tree" EXACT [] xref: EMAPA:37098 {source="MA:th"} xref: FMA:14753 xref: MA:0002036 xref: NCIT:C52741 xref: SCTID:19215005 xref: UMLS:C0226333 {source="ncithesaurus:Left_Renal_Artery"} is_a: UBERON:0001184 ! renal artery intersection_of: UBERON:0001184 ! renal artery intersection_of: supplies UBERON:0004538 ! left kidney relationship: supplies UBERON:0004538 ! left kidney property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001187 name: testicular artery namespace: uberon def: "One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Testicular_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria testicularis" RELATED LATIN [Wikipedia:Testicular_artery] synonym: "internal spermatic" RELATED [Wikipedia:Testicular_artery] synonym: "internal spermatic arteries" RELATED [Wikipedia:Testicular_artery] synonym: "internal spermatic artery" RELATED [Wikipedia:Testicular_artery] synonym: "internal spermatic vessels" RELATED [Wikipedia:Testicular_artery] synonym: "spermatic arteries" RELATED [Wikipedia:Testicular_artery] synonym: "spermatic artery" RELATED [Wikipedia:Testicular_artery] synonym: "spermatic vessels" RELATED [Wikipedia:Testicular_artery] synonym: "testicular arterial tree" EXACT [] synonym: "testicular arteries" RELATED [Wikipedia:Testicular_artery] xref: EMAPA:18621 xref: FMA:14758 xref: MA:0002063 xref: SCTID:244281003 xref: Wikipedia:Testicular_artery is_a: UBERON:0010192 ! genital artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000473 ! testis relationship: supplies UBERON:0000473 ! testis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001188 name: right testicular artery namespace: uberon def: "A testicular artery that supplies a right testicle." [OBOL:automatic] subset: human_reference_atlas synonym: "right spermatic artery" EXACT [] synonym: "trunk of right testicular arterial tree" EXACT [] xref: EMAPA:37382 {source="MA:th"} xref: FMA:14759 xref: MA:0002042 xref: NCIT:C52738 xref: UMLS:C0734076 {source="ncithesaurus:Right_Spermatic_Artery"} is_a: UBERON:0001187 ! testicular artery is_a: UBERON:0003468 ! ureteric segment of renal artery intersection_of: UBERON:0001187 ! testicular artery intersection_of: supplies UBERON:0004534 ! right testis relationship: supplies UBERON:0001222 ! right ureter relationship: supplies UBERON:0004534 ! right testis property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001189 name: left testicular artery namespace: uberon def: "A testicular artery that supplies a left testicle." [OBOL:automatic] subset: human_reference_atlas synonym: "left spermatic artery" EXACT [] synonym: "trunk of left testicular arterial tree" EXACT [] xref: EMAPA:37099 {source="MA:th"} xref: FMA:14760 xref: MA:0002041 xref: NCIT:C52739 xref: UMLS:C0734077 {source="ncithesaurus:Left_Spermatic_Artery"} is_a: UBERON:0001187 ! testicular artery is_a: UBERON:0003468 ! ureteric segment of renal artery intersection_of: UBERON:0001187 ! testicular artery intersection_of: supplies UBERON:0004533 ! left testis relationship: supplies UBERON:0001223 ! left ureter relationship: supplies UBERON:0004533 ! left testis property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001190 name: ovarian artery namespace: uberon def: "An artery that supplies an ovary." [OBOL:automatic] subset: human_reference_atlas subset: uberon_slim synonym: "arteria ovarica" RELATED LATIN [Wikipedia:Ovarian_artery] synonym: "ovarian arterial tree" EXACT [] xref: EMAPA:18620 xref: FMA:14761 xref: MA:0002012 xref: NCIT:C33242 xref: SCTID:244280002 xref: UMLS:C0226411 {source="ncithesaurus:Ovarian_Artery"} xref: Wikipedia:Ovarian_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000992 ! ovary relationship: connected_to UBERON:0001516 ! abdominal aorta relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0000992 ! ovary property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ae/Gray1170.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "In human anatomy, the ovarian artery is a blood vessel that supplies oxygenated blood to the ovary. It arises from the abdominal aorta below the renal artery, and does not pass out of the abdomiproperty_value external_definitioncavity. It can be found in the suspensory ligament of the ovary. [WP]." xsd:string {source="Wikipedia:Ovarian_artery"} [Term] id: UBERON:0001191 name: common iliac artery namespace: uberon def: "The common iliac arteries are two large arteries, about 4cm long in adults but more than a centimetre in diameter, that originate from the aortic bifurcation. The arteries run inferolaterally, along the medial border of the psoas muscles to the pelvic brim, where they bifurcate into the external iliac artery and internal iliac artery. The common iliac artery, and all of its branches, exist as paired structures (that is to say, there is one on the left side and one on the right). The distribution of the common iliac artery is basically the pelvis and lower limb on the corresponding side. Both common iliac arteries are accompanied along their course by common iliac veins. [WP,unvetted]." [Wikipedia:Common_iliac_artery] comment: See notes for parent class subset: human_reference_atlas subset: uberon_slim synonym: "arteria iliaca communis" RELATED LATIN [Wikipedia:Common_iliac_artery] synonym: "common iliac arterial tree" EXACT [] xref: EHDAA2:0000311 xref: EHDAA:2553 xref: EMAPA:17310 xref: FMA:14764 xref: MA:0001972 xref: NCIT:C32357 xref: SCTID:362050007 xref: UMLS:C1261084 {source="ncithesaurus:Common_Iliac_Artery"} xref: Wikipedia:Common_iliac_artery is_a: UBERON:0005609 {source="MA"} ! iliac artery is_a: UBERON:0012254 ! abdominal aorta artery relationship: develops_from UBERON:0005458 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="requires review", source="EHDAA2"} ! left umbilical artery relationship: develops_from UBERON:0005470 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="requires review", source="EHDAA2"} ! right umbilical artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6e/Iliac_artery_bifurcation_and_aorta.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001193 name: hepatic artery namespace: uberon def: "An artery that supplies the liver." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Hepatic_artery_proper] subset: human_reference_atlas subset: uberon_slim subset: vertebrate_core synonym: "arteria hepatica" RELATED [BTO:0004307] synonym: "arteria hepatica propria" EXACT LATIN [] xref: BTO:0004307 xref: EMAPA:17859 xref: FMA:14769 xref: GAID:496 xref: galen:HepaticArtery xref: MA:0001963 xref: MESH:D006499 xref: NCIT:C32729 xref: SCTID:76015000 xref: TAO:0005161 xref: UMLS:C0019145 {source="ncithesaurus:Hepatic_Artery"} xref: ZFA:0005161 is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002107 ! liver relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0002107 ! liver property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4c/Common_and_proper_hepatic_artery.png" xsd:anyURI property_value: IAO:0000232 "currently defined in a generic fashion." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Artery that supplies blood to the liver.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005161", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001194 name: splenic artery namespace: uberon def: "An artery that supplies the spleen." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim synonym: "arteria lienalis" RELATED LATIN [Wikipedia:Splenic_artery] synonym: "arteria splenica" EXACT LATIN [Wikipedia:Splenic_artery] synonym: "lienal artery" EXACT [MA:0001991] xref: EMAPA:19216 xref: FMA:14773 xref: GAID:510 xref: galen:SplenicArtery xref: MA:0001991 xref: MA:0003177 xref: MESH:D013157 xref: NCIT:C33597 xref: SCTID:244266009 xref: UMLS:C0037996 {source="ncithesaurus:Splenic_Artery"} xref: Wikipedia:Splenic_artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002106 ! spleen disjoint_from: UBERON:0001640 ! celiac artery relationship: branching_part_of UBERON:0001640 ! celiac artery relationship: part_of UBERON:0001640 ! celiac artery relationship: supplies UBERON:0002106 ! spleen property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a2/Gray1188.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/268" xsd:anyURI [Term] id: UBERON:0001199 name: mucosa of stomach namespace: uberon def: "The mucosal layer that lines the stomach." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "gastric mucosa" EXACT [] synonym: "gastric mucous membrane" EXACT [] synonym: "Magenschleimhaut" RELATED [BTO:0001308] synonym: "mucosa of organ of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of ventriculus" EXACT [OBOL:automatic] synonym: "mucosa of ventriculus" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach" EXACT [] synonym: "mucous membrane of ventriculus" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of ventriculus" EXACT [OBOL:automatic] synonym: "stomach mucosa" EXACT [] synonym: "stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach mucous membrane" EXACT [OBOL:automatic] synonym: "stomach organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (gaster)" EXACT [] synonym: "tunica mucosa gastricae" EXACT LATIN [FMA:14907, FMA:TA] synonym: "tunica mucosa gastris" RELATED LATIN [BTO:0001308, Wikipedia:Gastric_mucosa] synonym: "ventriculus mucosa" EXACT [OBOL:automatic] synonym: "ventriculus mucosa of organ" EXACT [OBOL:automatic] synonym: "ventriculus mucous membrane" EXACT [OBOL:automatic] synonym: "ventriculus organ mucosa" EXACT [OBOL:automatic] xref: BTO:0001308 xref: CALOHA:TS-0404 xref: EMAPA:35817 xref: FMA:14907 xref: GAID:321 xref: galen:GastricMucosa xref: MA:0002683 xref: MESH:D005753 xref: NCIT:C32656 xref: SCTID:362131005 xref: UMLS:C0017136 {source="ncithesaurus:Gastric_Mucosa"} xref: Wikipedia:Gastric_mucosa is_a: UBERON:0004786 ! gastrointestinal system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000945 ! stomach relationship: capable_of GO:0001696 ! gastric acid secretion relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach relationship: part_of UBERON:0001167 ! wall of stomach property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/1/1c/Normal_gastric_mucosa_intermed_mag.jpg" xsd:anyURI property_value: UBPROP:0000001 "The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits. In men it is about 1 mm thick and its surface is smooth, soft, and velvety. It consists of epithelium, lamina propria, and the muscularis mucosae. In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the organ it is thrown into numerous plaits or rugae, which, for the most part, have a longitudinal direction, and are most marked toward the pyloric end of the stomach, and along the greater curvature. These folds are entirely obliterated when the organ becomes distended. When examined with a lens, the inner surface of the mucous membrane presents a peculiar honeycomb appearance from being covered with funnel-like depressions or foveolae of a polygonal or hexagonal form, which vary from 0.12 to 0.25 mm. in diameter. These are the ducts of the gastric glands, and at the bottom of each may be seen one or more minute orifices, the openings of the gland tubes. Gastric glands are simple or branched tubular glands that emerge on the deeper part of the gastric foveola, inside the gastric areas and outlined by the folds of the mucosa. There are three types of glands: cardiac glands (in the proximal part of the stomach), oxyntic glands (the dominating type of gland), and pyloric glands. The cardiac glands mainly contain mucus producing cells. The bottom part of the oxyntic glands is dominated by zymogen (chief) cells that produce pepsinogen (an inactive precursor of the pepsin enzyme). Parietal cells, which secrete hydrochloric acid are scattered in the glands, with most of them in the middle part. The upper part of the glands consist of mucous neck cells; in this part the dividing cells are seen. The pyloric glands contain mucus-secreting cells. Several types of endocrine cells are found in all regions of the gastric mucosa. In the pyloric glands contain gastrin producing cells (G cells); this hormone stimulates acid production from the parietal cells. ECL (enterochromaffine-like) cells, found in the oxyntic glands release histamine, which also is a powerful stimulant of the acid secretion. The A cells produce glucagon, which mobilizes the hepatic glycogen, and the enterochromaffin cells that produce serotonin, which stimulates the contraction of the smooth muscles. The surface of the mucous membrane is covered by a single layer of columnar epithelium . This epithelium commences very abruptly at the cardiac orifice, where there is a sudden transition from the stratified epithelium of the esophagus. The epithelial lining of the gland ducts is of the same character and is continuous with the general lining of the stomach. [WP,unvetted][Wikipedia:Gastric_mucosa]." xsd:string {source="Wikipedia:Gastric_mucosa"} [Term] id: UBERON:0001200 name: submucosa of stomach namespace: uberon def: "The fibrous connective tissue layer beneath the stomach mucosa." [MGI:csmith, MP:0010794] subset: pheno_slim synonym: "gastric submucosa" EXACT [] synonym: "stomach submucosa" EXACT [] synonym: "submucosa of ventriculus" EXACT [OBOL:automatic] synonym: "submucous layer of stomach" RELATED [BTO:0002110] synonym: "tela submucosa (gaster)" EXACT [] synonym: "tela submucosa gastricae" EXACT LATIN [FMA:14908, FMA:TA] synonym: "tela submucosa ventriculi" RELATED [BTO:0002110] synonym: "ventriculus submucosa" EXACT [OBOL:automatic] xref: BTO:0002110 xref: EMAPA:35825 xref: FMA:14908 xref: MA:0002685 xref: NCIT:C32663 xref: SCTID:52459002 xref: UMLS:C0227211 {source="ncithesaurus:Gastric_Submucosa"} is_a: UBERON:0018257 ! submucosa of digestive tract intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000945 ! stomach relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach relationship: part_of UBERON:0001167 ! wall of stomach [Term] id: UBERON:0001201 name: serosa of stomach namespace: uberon def: "The outermost layer of the stomach wall, consisting of layers of connective tissue continuous with the peritoneum." [MGI:csmith, MP:0010793] subset: pheno_slim synonym: "anatomical wall of stomach serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of stomach serous membrane" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of ventriculus serous membrane" EXACT [OBOL:automatic] synonym: "gastric serosa" RELATED [] synonym: "gastric wall serosa" EXACT [OBOL:automatic] synonym: "gastric wall serous membrane" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "serosa of gastric wall" EXACT [OBOL:automatic] synonym: "serosa of stomach anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of stomach wall" EXACT [OBOL:automatic] synonym: "serosa of ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of ventriculus wall" EXACT [OBOL:automatic] synonym: "serosa of wall of stomach" EXACT [OBOL:automatic] synonym: "serosa of wall of ventriculus" EXACT [OBOL:automatic] synonym: "serous coat of stomach" EXACT [] synonym: "serous membrane of anatomical wall of stomach" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of ventriculus" EXACT [OBOL:automatic] synonym: "serous membrane of gastric wall" EXACT [OBOL:automatic] synonym: "serous membrane of stomach anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of stomach wall" EXACT [OBOL:automatic] synonym: "serous membrane of ventriculus anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of ventriculus wall" EXACT [OBOL:automatic] synonym: "serous membrane of wall of stomach" EXACT [OBOL:automatic] synonym: "serous membrane of wall of ventriculus" EXACT [OBOL:automatic] synonym: "stomach anatomical wall serosa" EXACT [OBOL:automatic] synonym: "stomach anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "stomach serosa" EXACT [] synonym: "stomach wall serosa" EXACT [OBOL:automatic] synonym: "stomach wall serous membrane" EXACT [OBOL:automatic] synonym: "tunica serosa (gaster)" EXACT [] synonym: "tunica serosa gastricae" EXACT LATIN [FMA:14914, FMA:TA] synonym: "ventriculus anatomical wall serosa" EXACT [OBOL:automatic] synonym: "ventriculus anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "ventriculus wall serosa" EXACT [OBOL:automatic] synonym: "ventriculus wall serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of stomach" EXACT [] synonym: "wall of stomach serosa" EXACT [OBOL:automatic] synonym: "wall of stomach serous membrane" EXACT [OBOL:automatic] synonym: "wall of ventriculus serosa" EXACT [OBOL:automatic] synonym: "wall of ventriculus serous membrane" EXACT [OBOL:automatic] xref: EMAPA:35822 xref: FMA:14914 xref: MA:0001626 xref: NCIT:C32662 xref: SCTID:1353004 xref: UMLS:C1517453 {source="ncithesaurus:Gastric_Serosal_Surface"} is_a: UBERON:0004782 ! gastrointestinal system serosa intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001167 ! wall of stomach relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach relationship: part_of UBERON:0001167 ! wall of stomach property_value: editor_note "TODO - check serosa/peritoneum" xsd:string [Term] id: UBERON:0001202 name: pyloric sphincter namespace: uberon def: "A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "pyloric valve" EXACT [Wikipedia:Pylorus] xref: AAO:0011093 xref: EMAPA:19251 xref: FMA:14916 xref: MA:0002952 xref: NCIT:C33433 xref: SCTID:268073008 xref: UMLS:C0227238 {source="ncithesaurus:Pyloric_Sphincter"} xref: VHOG:0001466 xref: XAO:0000457 is_a: UBERON:0011185 ! gastrointestinal sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0001166 ! pylorus relationship: adjacent_to UBERON:0002114 ! duodenum relationship: continuous_with UBERON:0008858 ! pyloric canal relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus relationship: part_of UBERON:0001166 ! pylorus property_value: RO:0002161 NCBITaxon:8355 property_value: UBPROP:0000003 "(...) the adult Xenopus stomach exhibits both glandular and aglandular regions and a distinct pyloric sphincter similar to that of the amniotic vertebrates (...).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001466", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00076.x", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001204 name: mucosa of small intestine namespace: uberon def: "A mucosa that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of small bowel" EXACT [OBOL:automatic] synonym: "mucosa of organ of small intestine" EXACT [OBOL:automatic] synonym: "mucosa of small bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of small bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of small intestine" EXACT [] synonym: "organ mucosa of small bowel" EXACT [OBOL:automatic] synonym: "organ mucosa of small intestine" EXACT [OBOL:automatic] synonym: "small bowel mucosa" EXACT [OBOL:automatic] synonym: "small bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "small bowel mucous membrane" EXACT [OBOL:automatic] synonym: "small bowel organ mucosa" EXACT [OBOL:automatic] synonym: "small intestinal mucosa" EXACT [] synonym: "small intestine mucosa" EXACT [] synonym: "small intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "small intestine mucous membrane" EXACT [] synonym: "small intestine organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (intestinum tenue)" EXACT [] synonym: "tunica mucosa intestini tenuis" EXACT LATIN [FMA:14933, FMA:TA] xref: BTO:0001259 xref: CALOHA:TS-0941 xref: EMAPA:35780 xref: FMA:14933 xref: MA:0002686 xref: NCIT:C33568 xref: SCTID:362144000 xref: UMLS:C0227261 {source="ncithesaurus:Small_Intestinal_Mucosa"} is_a: UBERON:0001242 ! intestinal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 ! wall of small intestine relationship: part_of UBERON:0001242 ! intestinal mucosa [Term] id: UBERON:0001205 name: submucosa of small intestine namespace: uberon def: "Submucosal tissue in the small intestines." [Wikipedia:Small_intestinal_submucosa] subset: uberon_slim synonym: "small bowel submucosa" EXACT [OBOL:automatic] synonym: "small intestinal submucosa" EXACT [] synonym: "small intestine submucosa" EXACT [] synonym: "submucosa of small bowel" EXACT [OBOL:automatic] synonym: "tela submucosa (intestinum tenue)" EXACT [] synonym: "tela submucosa intestini tenuis" EXACT LATIN [BTO:0002112] xref: BTO:0002112 xref: EMAPA:37564 {source="MA:th"} xref: FMA:14934 xref: MA:0001562 xref: NCIT:C33572 xref: SCTID:691000 xref: UMLS:C0227268 {source="ncithesaurus:Small_Intestinal_Submucosa"} xref: Wikipedia:Small_intestinal_submucosa is_a: UBERON:0009566 ! intestinal submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 ! wall of small intestine [Term] id: UBERON:0001206 name: serosa of small intestine namespace: uberon def: "A serous membrane that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] synonym: "serosa of small bowel" EXACT [OBOL:automatic] synonym: "serous coat of small intestine" EXACT [] synonym: "serous membrane of small bowel" EXACT [OBOL:automatic] synonym: "serous membrane of small intestine" EXACT [OBOL:automatic] synonym: "small bowel serosa" EXACT [OBOL:automatic] synonym: "small bowel serous membrane" EXACT [OBOL:automatic] synonym: "small intestinal serosa" EXACT [] synonym: "small intestine serosa" EXACT [] synonym: "small intestine serous membrane" EXACT [OBOL:automatic] synonym: "tunica serosa (intestinum tenue)" EXACT [] synonym: "tunica serosa intestini tenuis" EXACT LATIN [FMA:14938, FMA:TA] synonym: "visceral peritoneum of small intestine" EXACT [] xref: EMAPA:37561 {source="MA:th"} xref: FMA:14938 xref: MA:0001558 xref: SCTID:8266009 is_a: UBERON:0001243 ! serosa of intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 ! wall of small intestine relationship: part_of UBERON:0001243 ! serosa of intestine property_value: UBPROP:0000010 "duodenum, 1st part serosa, 2nd - 4th adventitia" xsd:string [Term] id: UBERON:0001207 name: mucosa of large intestine namespace: uberon def: "A mucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "large intestinal mucosa" EXACT [] synonym: "large intestine mucosa" EXACT [] synonym: "large intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "large intestine mucous membrane" EXACT [OBOL:automatic] synonym: "large intestine organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of large intestine" EXACT [OBOL:automatic] synonym: "mucous membrane of large intestine" EXACT [] synonym: "organ mucosa of large intestine" EXACT [OBOL:automatic] synonym: "tunica mucosa intestini crassi" EXACT LATIN [FMA:14969, FMA:TA] xref: CALOHA:TS-2106 xref: EMAPA:35467 xref: FMA:14969 xref: MA:0002688 xref: NCIT:C32926 xref: UMLS:C0734203 {source="ncithesaurus:Large_Intestinal_Mucosa"} is_a: UBERON:0001242 ! intestinal mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 ! wall of large intestine relationship: part_of UBERON:0001242 ! intestinal mucosa [Term] id: UBERON:0001208 name: submucosa of large intestine namespace: uberon def: "A submucosa that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "large intestinal submucosa" EXACT [] synonym: "large intestine submucosa" EXACT [] synonym: "submucous layer of large intestine" RELATED [BTO:0002111] synonym: "tela submucosa intestini crassi" EXACT LATIN [FMA:14970, FMA:TA] xref: BTO:0002111 xref: EMAPA:37560 {source="MA:th"} xref: FMA:14970 xref: MA:0002690 xref: NCIT:C32930 xref: UMLS:C0734204 {source="ncithesaurus:Large_Intestinal_Submucosa"} is_a: UBERON:0009566 ! intestinal submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 ! wall of large intestine [Term] id: UBERON:0001209 name: serosa of large intestine namespace: uberon def: "A serous membrane that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "large intestinal serosa" EXACT [] synonym: "large intestine serosa" EXACT [] synonym: "large intestine serous membrane" EXACT [OBOL:automatic] synonym: "serous coat of large intestine" EXACT [] synonym: "serous membrane of large intestine" EXACT [OBOL:automatic] synonym: "tunica serosa intestini crassi" EXACT LATIN [FMA:14975, FMA:TA] synonym: "visceral peritoneum of large intestine" EXACT [] xref: EMAPA:37557 {source="MA:th"} xref: FMA:14975 xref: MA:0001546 xref: NCIT:C32929 xref: UMLS:C1517727 {source="ncithesaurus:Large_Intestinal_Serosal_Surface"} is_a: UBERON:0001243 ! serosa of intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 ! wall of large intestine relationship: part_of UBERON:0001243 ! serosa of intestine property_value: editor_note "TODO - check serosa/peritoneum" xsd:string [Term] id: UBERON:0001212 name: duodenal gland namespace: uberon def: "A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]." [Wikipedia:Brunner's_glands] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "Brunner's gland" EXACT [FMA:15060] synonym: "gland of Brunner" EXACT [FMA:15060] synonym: "glandula duodenales" RELATED LATIN [BTO:0002376] synonym: "glandula duodenales Brunneri" RELATED LATIN [BTO:0002376] synonym: "submucosal gland of duodenum" EXACT [] xref: BTO:0002376 xref: EMAPA:36522 xref: FMA:15060 xref: GAID:314 xref: MA:0001551 xref: MESH:D002011 xref: NCIT:C13010 xref: SCTID:41298001 xref: UMLS:C0006323 {source="ncithesaurus:Brunner_s_Gland"} xref: Wikipedia:Brunner's_glands is_a: UBERON:0003408 ! gland of digestive tract is_a: UBERON:0011148 {notes="compound tubular"} ! submucosal gland intersection_of: UBERON:0011148 ! submucosal gland intersection_of: part_of UBERON:0002114 ! duodenum relationship: located_in UBERON:0003332 {source="FMA, modified"} ! submucosa of duodenum relationship: only_in_taxon NCBITaxon:40674 {notes="unclear for Aves", source="ISBN:9780521617147"} ! Mammalia relationship: part_of UBERON:0002114 ! duodenum property_value: editor_note "currently defined as equivalent to any submucosal gland in the duodenum." xsd:string property_value: UBPROP:0000008 "Said to be absent outside mammlian (Andrew 1959) but Ziswiler and Farner (1972) noted similar glands at the gastroduodenal junction of some birds" xsd:string {source="ISBN:9780521617147"} [Term] id: UBERON:0001213 name: intestinal villus namespace: uberon alt_id: UBERON:0007607 def: "The tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold." [MGI:csmith, MGI:rbabiuk, MP:0008108] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "enteric villi" EXACT PLURAL [HP:0011473] synonym: "enteric villous" EXACT [HP:0011473] synonym: "enteric villus" EXACT [HP:0011473] synonym: "intestinal villi" EXACT PLURAL [ZFA:0005125] synonym: "intestinal villus layer" RELATED [] synonym: "small intestine villus" RELATED [MA:0001563] synonym: "villi intestinales" EXACT PLURAL [] synonym: "villi intestinales" RELATED LATIN [Wikipedia:Intestinal_villus] synonym: "villus" EXACT [BTO:0003121] synonym: "villus intestinalis (intestinum tenue)" EXACT [FMA:15072] xref: BTO:0003121 xref: EMAPA:35784 xref: FMA:15072 xref: MA:0001563 xref: NCIT:C33874 xref: SCTID:23230007 xref: TAO:0005125 xref: UMLS:C1519988 {source="ncithesaurus:Villus"} xref: Wikipedia:Intestinal_villus xref: ZFA:0005125 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: has_part UBERON:0001981 ! blood vessel relationship: has_part UBERON:0012425 ! striated border microvillus layer relationship: part_of UBERON:0001204 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="may be present in other parts in other species", source="FMA"} ! mucosa of small intestine relationship: part_of UBERON:0001277 {source="ZFA"} ! intestinal epithelium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/38/Small_intestine_low_mag.jpg" xsd:anyURI property_value: editor_note "in mammals, villi are (largely?) absent from the large intestine, so we treat this as equivalent to small intestinal villus. small/large subdivision may not make sense for all species for which this is present (see ZFA). Note that VHOG quotes ISBN:978-0030223693 as suggesting there are some villi in the large intestine" xsd:string property_value: UBPROP:0000001 "The entire digestive tract is lined by well developed villi, which are longest in the intestinal bulb and decrease progressively in size towards the caudal end of the intestine. No crypts are present, but, the regions between the villi, the intervillus pockets, have a crypt-like function. Cells are produced in the intervillus pockets and shed from the villus tips. Crosnier et al. 2005[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005125", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000012 "the BTO class refers to a generic villous" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0001215 name: inferior mesenteric vein namespace: uberon def: "A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]." [Wikipedia:Inferior_mesenteric_vein] subset: human_reference_atlas subset: uberon_slim synonym: "lower mesenteric vein" RELATED [BTO:0002782] synonym: "vena mesenterica inferior" RELATED LATIN [Wikipedia:Inferior_mesenteric_vein] xref: BTO:0002782 xref: EHDAA2:0000819 xref: EHDAA:8712 xref: EMAPA:18642 xref: FMA:15391 xref: MA:0002178 xref: NCIT:C32782 xref: SCTID:281055007 xref: UMLS:C0226754 {source="ncithesaurus:Inferior_Mesenteric_Vein"} xref: VHOG:0001118 xref: Wikipedia:Inferior_mesenteric_vein is_a: UBERON:0005617 ! mesenteric vein intersection_of: UBERON:0005617 ! mesenteric vein intersection_of: drains UBERON:0000059 ! large intestine relationship: drains UBERON:0000059 ! large intestine relationship: tributary_of UBERON:0003713 {source="FMA/obol"} ! splenic vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001222 name: right ureter namespace: uberon def: "An ureter that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37373 {source="MA:th"} xref: FMA:15571 xref: MA:0001685 xref: NCIT:C49327 xref: SCTID:276251000 xref: UMLS:C0227682 {source="ncithesaurus:Right_Ureter"} is_a: UBERON:0000056 ! ureter intersection_of: UBERON:0000056 ! ureter intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0001223 name: left ureter namespace: uberon def: "An ureter that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37372 {source="MA:th"} xref: FMA:15572 xref: MA:0001684 xref: NCIT:C49324 xref: SCTID:276340002 xref: UMLS:C0227683 {source="ncithesaurus:Left_Ureter"} is_a: UBERON:0000056 ! ureter intersection_of: UBERON:0000056 ! ureter intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0001224 name: renal pelvis namespace: uberon def: "A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]." [MP:0004194] comment: In this ontology, the renal pelvis is represented as the area of part-overlap between the kidney and the ureter subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "kidney pelvis" EXACT [] synonym: "p. renallis" RELATED LATIN [Wikipedia:Renal_pelvis] synonym: "pelvis of ureter" EXACT [] synonym: "pyelum" RELATED [MP:0004194] xref: CALOHA:TS-2230 xref: EMAPA:17948 xref: FMA:15575 xref: GAID:426 xref: galen:RenalPelvis xref: MA:0000374 xref: MESH:D007682 xref: NCIT:C12887 xref: SCTID:362221007 xref: UMLS:C0227666 {source="ncithesaurus:Renal_Pelvis"} xref: Wikipedia:Renal_pelvis is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000064 ! organ part is_a: UBERON:0004111 ! anatomical conduit disjoint_from: UBERON:0002355 ! pelvic region of trunk relationship: channel_for UBERON:0001088 ! urine relationship: channels_from UBERON:0002113 ! kidney relationship: channels_into UBERON:0000056 ! ureter relationship: continuous_with UBERON:0000056 {source="FMA"} ! ureter relationship: contributes_to_morphology_of UBERON:0000056 ! ureter relationship: part_of UBERON:0002113 {source="MA"} ! kidney relationship: part_of UBERON:0036295 ! renal pelvis/ureter property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/c0/Illu_kidney2.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001225 name: cortex of kidney namespace: uberon def: "Outer cortical portion of the kidney, between the renal capsule and the renal medulla." [Wikipedia:Renal_cortex] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "cortex renalis" EXACT LATIN [FMA:15581, FMA:TA] synonym: "kidney cortex" EXACT [] synonym: "renal cortex" EXACT [] xref: BTO:0001166 xref: CALOHA:TS-0503 xref: EMAPA:17952 xref: FMA:15581 xref: GAID:424 xref: galen:CortexOfKidney xref: MA:0000372 xref: MESH:D007672 xref: NCIT:C12739 xref: SCTID:362211004 xref: UMLS:C0022655 {source="ncithesaurus:Renal_Cortex"} xref: Wikipedia:Renal_cortex is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001851 ! cortex intersection_of: UBERON:0001851 ! cortex intersection_of: part_of UBERON:0002113 ! kidney relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: part_of UBERON:0008987 {source="FMA"} ! renal parenchyma property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000010 "In the adult metanephros, it forms a continuous smooth outer zone with a number of projections that extend down between the pyramids. It contains the renal corpuscles and the renal tubules except for parts of the loop of Henle which descend into the renal medulla. It also contains blood vessels and cortical collecting ducts. The renal cortex is the part of the kidney where ultrafiltration occurs.[WP]" xsd:string [Term] id: UBERON:0001231 name: nephron tubule namespace: uberon alt_id: UBERON:0004210 def: "An epithelial tube that is part of the nephron, the functional part of the kidney." [GO:0072078, Wikipedia:Renal_tubule] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "kidney tubule" EXACT [GAID:433] synonym: "renal tubule" BROAD [] synonym: "tubulus renalis" EXACT [] synonym: "uriniferous tubule" RELATED [MA:0000377] xref: BTO:0000343 xref: CALOHA:TS-1262 xref: EFO:0003666 xref: EMAPA:27782 xref: EV:0100387 xref: FMA:15627 xref: GAID:433 xref: MA:0000377 xref: MESH:D007684 xref: NCIT:C49274 xref: SCTID:361332007 xref: TAO:0001287 xref: UMLS:C0022674 {source="ncithesaurus:Renal_Tubule"} xref: Wikipedia:Renal_tubule xref: ZFA:0001287 is_a: UBERON:0004211 ! nephron epithelium is_a: UBERON:0009773 {source="GO"} ! renal tubule intersection_of: UBERON:0003914 {source="GO", source="MA", source="ZFA"} ! epithelial tube intersection_of: part_of UBERON:0001285 {source="GO", source="MA", source="ZFA"} ! nephron relationship: contributes_to_morphology_of UBERON:0001285 ! nephron relationship: develops_from UBERON:0003918 {notes="checkme"} ! kidney mesenchyme relationship: has_part CL:0005009 {source="ZFA"} ! renal principal cell property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "note that in ISBN:0073040584 (Vertebrates, Kardong), the uriniferous tubule contains the nephron, so we have a separate class, rather than using a synonym, as in MA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001232 name: collecting duct of renal tubule namespace: uberon def: "The collecting duct is a portion of the nephron through which water flows, moving passively down its concentration gradient." [GO:0072044, Wikipedia:Collecting_tubule] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arcuate renal tubule" RELATED [Wikipedia:Connecting_tubule] synonym: "collecting duct" EXACT [GO:0072044] synonym: "collecting duct system" RELATED [BTO:0000761] synonym: "collecting tubule" RELATED [] synonym: "junctional tube" RELATED [Wikipedia:Connecting_tubule] synonym: "kidney collecting duct" EXACT [] synonym: "kidney collecting tubule" RELATED [] synonym: "renal collecting tubule" EXACT [FMA:15628] synonym: "tubulus renalis arcuatus" EXACT LATIN [Wikipedia:Connecting_tubule] synonym: "tubulus renalis colligens" EXACT [] synonym: "ureteric tree" RELATED [EMAPA:28407] xref: BTO:0000761 xref: CALOHA:TS-0860 xref: EMAPA:28407 xref: EV:0100391 xref: FMA:15628 xref: GAID:434 xref: MA:0000371 xref: MESH:D007685 xref: SCTID:28202009 xref: TAO:0005294 xref: Wikipedia:Collecting_tubule xref: ZFA:0005294 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006555 ! excretory tube relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: part_of UBERON:0001285 {notes="checkme", source="GO"} ! nephron relationship: part_of UBERON:0004100 ! renal collecting system property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Renal duct that collects the output from renal tubules.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005294", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000012 "in ISBN:0073040584 (Vertebrates, Kardong), the nephron is adjacent to the collecting tubule, consistent with FMA, but not GO. Wikipedia says: Many sources include the connecting tubule as part of the collecting duct system. However, the embryological origin is more similar to the nephron than it is to the rest of the collecting duct (which derives from the ureteric bud), and other sources therefore classify the connecting tubule with the nephron" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001238 name: lamina propria of small intestine namespace: uberon def: "Lamina propria that is part_of the small intestine." [GOC:Obol] synonym: "lamina propria mucosa of small bowel" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of small intestine" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of small bowel" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of small intestine" EXACT [] synonym: "lamina propria of mucosa of small intestine" EXACT [] synonym: "lamina propria of small bowel" EXACT [OBOL:automatic] synonym: "small bowel lamina propria" EXACT [OBOL:automatic] synonym: "small bowel lamina propria mucosa" EXACT [OBOL:automatic] synonym: "small bowel lamina propria mucosae" EXACT [OBOL:automatic] synonym: "small intestine lamina propria" EXACT [] synonym: "small intestine lamina propria mucosa" EXACT [OBOL:automatic] synonym: "small intestine lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:35779 xref: FMA:15651 xref: MA:0001554 xref: NCIT:C49297 xref: SCTID:63588008 xref: UMLS:C1711325 {source="ncithesaurus:Small_Intestinal_Lamina_Propria"} is_a: UBERON:0004780 ! gastrointestinal system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001204 ! mucosa of small intestine [Term] id: UBERON:0001242 name: intestinal mucosa namespace: uberon def: "Mucosal layer that lines the intestine." [UBERON:cjm] subset: pheno_slim subset: uberon_slim synonym: "bowel mucosa" EXACT [OBOL:automatic] synonym: "bowel mucosa of organ" EXACT [OBOL:automatic] synonym: "bowel mucous membrane" EXACT [OBOL:automatic] synonym: "bowel organ mucosa" EXACT [OBOL:automatic] synonym: "intestine mucosa" EXACT [] synonym: "intestine mucosa of organ" EXACT [OBOL:automatic] synonym: "intestine mucous membrane" EXACT [OBOL:automatic] synonym: "intestine organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bowel" EXACT [OBOL:automatic] synonym: "mucosa of intestine" EXACT [] synonym: "mucosa of organ of bowel" EXACT [OBOL:automatic] synonym: "mucosa of organ of intestine" EXACT [OBOL:automatic] synonym: "mucous membrane of bowel" EXACT [OBOL:automatic] synonym: "mucous membrane of intestine" EXACT [OBOL:automatic] synonym: "organ mucosa of bowel" EXACT [OBOL:automatic] synonym: "organ mucosa of intestine" EXACT [OBOL:automatic] synonym: "tunica mucosa intestini" EXACT [] xref: BTO:0000642 xref: EMAPA:35440 xref: FMA:15695 xref: GAID:296 xref: MA:0001537 xref: MESH:D007413 xref: NCIT:C49241 xref: SCTID:362080002 xref: UMLS:C0021839 {source="ncithesaurus:Intestinal_Mucosa"} is_a: UBERON:0004786 ! gastrointestinal system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001262 ! wall of intestine [Term] id: UBERON:0001243 name: serosa of intestine namespace: uberon def: "A serous membrane that is part of a wall of intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of bowel serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of bowel serous membrane" EXACT [OBOL:automatic] synonym: "anatomical wall of intestine serosa" EXACT [OBOL:automatic] synonym: "anatomical wall of intestine serous membrane" EXACT [OBOL:automatic] synonym: "bowel anatomical wall serosa" EXACT [OBOL:automatic] synonym: "bowel anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "bowel wall serosa" EXACT [OBOL:automatic] synonym: "bowel wall serous membrane" EXACT [OBOL:automatic] synonym: "intestinal serosa" EXACT [] synonym: "intestinal wall serosa" EXACT [OBOL:automatic] synonym: "intestinal wall serous membrane" EXACT [OBOL:automatic] synonym: "intestine anatomical wall serosa" EXACT [OBOL:automatic] synonym: "intestine anatomical wall serous membrane" EXACT [OBOL:automatic] synonym: "intestine serosa" EXACT [] synonym: "intestine wall serosa" EXACT [OBOL:automatic] synonym: "intestine wall serous membrane" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of bowel" EXACT [OBOL:automatic] synonym: "serosa of anatomical wall of intestine" EXACT [OBOL:automatic] synonym: "serosa of bowel anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of bowel wall" EXACT [OBOL:automatic] synonym: "serosa of intestinal wall" EXACT [OBOL:automatic] synonym: "serosa of intestine anatomical wall" EXACT [OBOL:automatic] synonym: "serosa of intestine wall" EXACT [OBOL:automatic] synonym: "serosa of wall of bowel" EXACT [OBOL:automatic] synonym: "serosa of wall of intestine" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of bowel" EXACT [OBOL:automatic] synonym: "serous membrane of anatomical wall of intestine" EXACT [OBOL:automatic] synonym: "serous membrane of bowel anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of bowel wall" EXACT [OBOL:automatic] synonym: "serous membrane of intestinal wall" EXACT [OBOL:automatic] synonym: "serous membrane of intestine anatomical wall" EXACT [OBOL:automatic] synonym: "serous membrane of intestine wall" EXACT [OBOL:automatic] synonym: "serous membrane of wall of bowel" EXACT [OBOL:automatic] synonym: "serous membrane of wall of intestine" EXACT [OBOL:automatic] synonym: "visceral peritoneum of intestine" EXACT [] synonym: "wall of bowel serosa" EXACT [OBOL:automatic] synonym: "wall of bowel serous membrane" EXACT [OBOL:automatic] synonym: "wall of intestine serosa" EXACT [OBOL:automatic] synonym: "wall of intestine serous membrane" EXACT [OBOL:automatic] xref: EMAPA:37619 {source="MA:th"} xref: FMA:15701 xref: MA:0001538 is_a: UBERON:0004782 ! gastrointestinal system serosa intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001262 ! wall of intestine property_value: editor_note "TODO - check serosa/peritoneum" xsd:string [Term] id: UBERON:0001245 name: anus namespace: uberon def: "Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts." [Wikipedia:Anus, ZFIN:curator] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "anal opening" EXACT [] synonym: "anal orifice" EXACT [] synonym: "opening of terminal part of digestive tract" EXACT [] synonym: "proctodeum" RELATED [] xref: BTO:0001680 xref: CALOHA:TS-2005 xref: EV:0100082 xref: FBbt:00047153 xref: FMA:15711 xref: GAID:312 xref: galen:Anus xref: MA:0000331 xref: NCIT:C43362 xref: SCTID:181262009 xref: TADS:0000066 xref: TGMA:0001279 xref: UMLS:C0003461 {source="ncithesaurus:Anus"} xref: WBbt:0005364 xref: Wikipedia:Anus is_a: UBERON:0000161 ! orifice is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000161 ! orifice intersection_of: distalmost_part_of UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0000931 ! proctodeum relationship: distalmost_part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/65/Protovsdeuterostomes.svg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/75/Anorectum.gif" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "anal" xsd:string property_value: UBPROP:0000008 "In the lungfish, sharks and rays the rectum opens into the cloaca which also receives wastes (urine) from the kidneys and material from the reproductive organs. In bony fish the rectum reaches the outside environment through the anus, which is normally situated just in front the urinary and reproductive openings. However in some fish the digestive tract may be curled back on itself, and in the Electric Eel (Electrophorus electricus) the anus is situated in the fish's throat. -- http://www.earthlife.net/fish/digestion.html" xsd:string [Term] id: UBERON:0001246 name: interlobular bile duct namespace: uberon def: "The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad." [MP:0009500] subset: pheno_slim synonym: "interlobular ductule" EXACT [MP:0009500] xref: FMA:15767 xref: MA:0002668 xref: NCIT:C32827 xref: SCTID:83488001 xref: UMLS:C0227515 {source="ncithesaurus:Interlobular_Bile_Duct"} xref: Wikipedia:Interlobular_bile_ducts is_a: UBERON:0003704 {source="FMA", source="MA-part-of"} ! intrahepatic bile duct relationship: connects UBERON:0004058 ! biliary ductule relationship: connects UBERON:0014719 ! intralobular duct relationship: contributes_to_morphology_of UBERON:0001279 ! portal triad relationship: part_of UBERON:0001279 {source="FMA", source="MA", source="MP"} ! portal triad [Term] id: UBERON:0001247 name: falciform ligament namespace: uberon def: "A ligament that attaches the liver to the anterior body wall. It is a broad and thin antero-posterior peritoneal fold, falciform in shape, its base being directed downward and backward and its apex upward and backward. It is a remnant of the ventral mesentery of the fetus. It is situated in an antero-posterior plane but lies obliquely, so that one surface faces forward and is in contact with the peritoneum behind the right rectus and the diaphragm, while the other is directed backward and is in contact with the left lobe of the liver. It is attached by its left margin to the under surface of the diaphragm and the posterior surface of the sheath of the right Rectus as low down as the umbilicus; by its right margin it extends from the notch on the anterior margin of the liver, as far back as the posterior surface. It is composed of two layers of peritoneum closely united together. Its base or free edge contains between its layers the round ligament and the paraumbilical veins[WP]." [Wikipedia:Falciform_ligament] subset: uberon_slim synonym: "falciform ligament of liver" EXACT [] synonym: "ligamentum falciforme (hepatis)" EXACT [] synonym: "ligamentum falciforme hepatis" EXACT LATIN [FMA:15823, FMA:TA] xref: EHDAA2:0000499 xref: EHDAA:4856 xref: EMAPA:18288 xref: FMA:15823 xref: MA:0001622 xref: NCIT:C32582 xref: SCTID:362705001 xref: UMLS:C0230240 {source="ncithesaurus:Falciform_Ligament"} xref: VHOG:0000355 xref: Wikipedia:Falciform_ligament is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0013139 ! ligament of liver intersection_of: UBERON:0008845 ! nonskeletal ligament intersection_of: attaches_to UBERON:0000309 ! body wall intersection_of: attaches_to UBERON:0002107 ! liver relationship: attaches_to UBERON:0000309 ! body wall relationship: attaches_to UBERON:0002107 ! liver relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0005626 {source="MA"} ! ventral mesogastrium property_value: UBPROP:0000012 "in FMA this is a subclass of mesentery. In MA it is a subclass of ligament, we infer and assert this is a nonskeletal ligament" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001252 name: adventitia of ureter namespace: uberon def: "An adventitia that is part of a ureter." [OBOL:automatic] synonym: "external adventitia of ureter" EXACT [] synonym: "tunica adventitia (ureter)" EXACT LATIN [FMA:15892, FMA:TA] synonym: "tunica adventitia ureteris" EXACT LATIN [FMA:15892, FMA:TA] synonym: "ureter adventitia" EXACT [] synonym: "ureteral adventitia" EXACT [] xref: EMAPA:28114 xref: FMA:15892 xref: MA:0002652 xref: SCTID:392273001 xref: SCTID:47879001 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005742 ! adventitia intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0009916 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of ureter [Term] id: UBERON:0001253 name: lamina propria of ureter namespace: uberon def: "A lamina propria that is part of a ureter [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "lamina propria mucosa of ureter" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of ureter" EXACT [OBOL:automatic] synonym: "ureter lamina propria" EXACT [] synonym: "ureter lamina propria mucosa" EXACT [OBOL:automatic] synonym: "ureter lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:28841 xref: FMA:15896 xref: MA:0002653 xref: SCTID:2771005 is_a: UBERON:0000030 ! lamina propria is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0004980 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mucosa of ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001255 name: urinary bladder namespace: uberon def: "Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]." [MGI:anna, Wikipedia:Urinary_bladder] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "bladder" BROAD [EHDAA2:0000174] synonym: "urocyst" RELATED [Wikipedia:Urinary_bladder] synonym: "vesica" RELATED [BTO:0001418] synonym: "vesica urinaria" EXACT LATIN [Wikipedia:Urinary_bladder] xref: AAO:0000623 xref: BTO:0001418 xref: CALOHA:TS-1090 xref: EFO:0000290 xref: EHDAA2:0000174 xref: EHDAA:9328 xref: EMAPA:18321 xref: EV:0100098 xref: FMA:15900 xref: GAID:0000004 xref: galen:UrinaryBladder xref: MA:0000380 xref: MAT:0000122 xref: MESH:D001743 xref: MIAA:0000122 xref: NCIT:C12414 xref: SCTID:302512001 xref: UMLS:C0005682 {source="ncithesaurus:Bladder"} xref: VHOG:0000740 xref: Wikipedia:Urinary_bladder xref: XAO:0000154 is_a: UBERON:0002075 ! viscus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0018707 {source="BTO"} ! bladder organ relationship: develops_from UBERON:0000164 {notes="upper part of UG sinus"} ! primitive urogenital sinus relationship: part_of UBERON:0001556 {source="FMA"} ! lower urinary tract property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/30/Urinary_system.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:8782 {editor="https://orcid.org/0000-0003-3308-6245", id="GOTAX:0010073", source="https://github.com/obophenotype/uberon/issues/454"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A saccular organ in which urine accumulates before discharge from the body. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000740", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Anatomical structure which consists of a membranous sac used to temporarily store urine until it is excreted from the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000623", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "In tetrapods, the urinary bladder arises as an outpocketing of the cloaca. (...) The tetrapod urinary bladder appears first among amphibians and is present in Sphenodon, turtles, most lizards, ostriches among birds, and all mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000740", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.577-78", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "vesical" xsd:string property_value: UBPROP:0000008 "The urinary bladder evolved in tetrapods. Birds to not possess a true urinary bladder, although Palaeognathae have an undifferentiated cloacal outpocketing that serves a similar function[https://github.com/obophenotype/uberon/issues/454]" xsd:string [Term] id: UBERON:0001256 name: wall of urinary bladder namespace: uberon def: "An anatomical wall that lines the insider of a urinary bladder." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim synonym: "anatomical wall of bladder" EXACT [OBOL:automatic] synonym: "anatomical wall of urinary bladder" EXACT [OBOL:automatic] synonym: "bladder anatomical wall" EXACT [OBOL:automatic] synonym: "bladder wall" EXACT [OBOL:automatic] synonym: "urinary bladder anatomical wall" EXACT [OBOL:automatic] synonym: "urinary bladder wall" EXACT [] synonym: "wall of bladder" EXACT [OBOL:automatic] xref: BTO:0001462 xref: EMAPA:35175 xref: FMA:15902 xref: MA:0002493 xref: NCIT:C48941 xref: SCTID:362225003 xref: UMLS:C0458421 {source="ncithesaurus:Bladder_Wall"} is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 ! urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001258 name: neck of urinary bladder namespace: uberon def: "The constricted portion of the urinary bladder, formed by the meeting of its inferolateral surfaces proximal to the opening of the urethra[MP]." [MP:anna, Wikipedia:Neck_of_urinary_bladder] subset: pheno_slim subset: uberon_slim synonym: "bladder neck" EXACT [] synonym: "cervix vesicae" EXACT LATIN [FMA:15912, FMA:TA] synonym: "cervix vesicae urinariae" RELATED LATIN [Wikipedia:Neck_of_urinary_bladder] synonym: "collum vesicae" EXACT LATIN [FMA:15912, FMA:TA] synonym: "neck of bladder" EXACT [] synonym: "urinary bladder neck" EXACT [] synonym: "vesical neck" EXACT [] xref: EMAPA:36078 xref: FMA:15912 xref: galen:UrinaryBladderNeck xref: MA:0002491 xref: NCIT:C12336 xref: SCTID:362227006 xref: UMLS:C0227716 {source="ncithesaurus:Bladder_Neck"} xref: Wikipedia:Neck_of_urinary_bladder is_a: UBERON:0001560 ! neck of organ is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: contributes_to_morphology_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 ! urinary bladder property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/63/Gray1156.png" xsd:anyURI [Term] id: UBERON:0001259 name: mucosa of urinary bladder namespace: uberon def: "The mucous membrane lining the urinary bladder." [MGI:anna, MP:0011766] subset: efo_slim subset: human_reference_atlas subset: pheno_slim synonym: "bladder mucosa" EXACT [] synonym: "bladder mucous membrane" EXACT [OBOL:automatic] synonym: "bladder organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of bladder" EXACT [] synonym: "mucous membrane of urinary bladder" EXACT [] synonym: "tunica mucosa (vesica urinaria)" EXACT LATIN [FMA:15928, FMA:TA] synonym: "tunica mucosa vesicae" EXACT LATIN [FMA:15928, FMA:TA] synonym: "tunica mucosa vesicae urinariae" EXACT [MP:MP] synonym: "urinary bladder mucosa" EXACT [] synonym: "urinary bladder mucous membrane" EXACT [OBOL:automatic] xref: EFO:0000293 xref: EMAPA:35897 xref: FMA:15928 xref: galen:MucousMembraneOfUrinaryBladder xref: MA:0001692 xref: NCIT:C32205 xref: SCTID:362224004 xref: UMLS:C0227691 {source="ncithesaurus:Bladder_Mucosa"} is_a: UBERON:0000344 ! mucosa is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: contributes_to_morphology_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001256 ! wall of urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001260 name: serosa of urinary bladder namespace: uberon def: "A serous membrane that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder serosa" EXACT [] synonym: "bladder serous membrane" EXACT [OBOL:automatic] synonym: "serosa of bladder" EXACT [] synonym: "serous coat of bladder" EXACT [] synonym: "serous coat of urinary bladder" EXACT [] synonym: "serous membrane of bladder" EXACT [OBOL:automatic] synonym: "serous membrane of urinary bladder" EXACT [OBOL:automatic] synonym: "tunica serosa (vesica urinaria)" EXACT LATIN [FMA:15932, FMA:TA] synonym: "tunica serosa vesicae" EXACT LATIN [FMA:15932, FMA:TA] synonym: "urinary bladder serosa" EXACT [] synonym: "urinary bladder serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of urinary bladder" EXACT [] xref: EMAPA:28661 xref: FMA:15932 xref: MA:0001696 xref: SCTID:5868002 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001256 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of urinary bladder property_value: editor_note "TODO - check serosa/peritoneum" xsd:string [Term] id: UBERON:0001261 name: lamina propria of urinary bladder namespace: uberon def: "A lamina propria that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "bladder lamina propria" EXACT [OBOL:automatic] synonym: "bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bladder lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of urinary bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of urinary bladder" EXACT [OBOL:automatic] synonym: "lamina propria of bladder" EXACT [OBOL:automatic] synonym: "urinary bladder lamina propria" EXACT [] synonym: "urinary bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:30088 xref: FMA:15935 xref: MA:0001695 xref: NCIT:C48940 xref: UMLS:C1706967 {source="ncithesaurus:Bladder_Lamina_Propria"} is_a: UBERON:0000030 ! lamina propria is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001259 ! mucosa of urinary bladder property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000010 "Contains loose to dense connective tissue, variably sized blood vessels that may be close to epithelium, lymphatics, variable adipose tissue" xsd:string [Term] id: UBERON:0001262 name: wall of intestine namespace: uberon def: "An anatomical wall that is part of a intestine [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical wall of bowel" EXACT [OBOL:automatic] synonym: "anatomical wall of intestine" EXACT [OBOL:automatic] synonym: "bowel anatomical wall" EXACT [OBOL:automatic] synonym: "bowel wall" EXACT [OBOL:automatic] synonym: "bowel wall" RELATED [MA:0001525] synonym: "intestinal wall" EXACT [] synonym: "intestine anatomical wall" EXACT [OBOL:automatic] synonym: "intestine wall" EXACT [] synonym: "wall of bowel" EXACT [OBOL:automatic] xref: BTO:0000647 xref: EMAPA:35444 xref: FMA:15949 xref: MA:0001525 xref: MA:0002693 xref: NCIT:C49478 xref: UMLS:C1708548 {source="ncithesaurus:Intestinal_Wall_Tissue"} is_a: UBERON:0000328 ! gut wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0000160 ! intestine property_value: editor_note "we place two MA classes here due to the official ncit2ma mapping to intestinal wall tissue; not clear how bowel and intestine are different" xsd:string [Term] id: UBERON:0001263 name: pancreatic acinus namespace: uberon def: "The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct." [MP:0009145] subset: human_reference_atlas subset: pheno_slim synonym: "acinus pancreaticus" EXACT LATIN [FMA:16011] synonym: "pancreas acinus" EXACT [] synonym: "pancreatic acinar" RELATED [] synonym: "pancreatic acini" RELATED PLURAL [] xref: EMAPA:35651 xref: FMA:16011 xref: MA:0002417 xref: NCIT:C49268 xref: SCTID:247604006 xref: UMLS:C0227578 {source="ncithesaurus:Pancreatic_Acinus"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013232 ! serous acinus intersection_of: UBERON:0009842 ! glandular acinus intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: composed_primarily_of CL:0002064 ! pancreatic acinar cell relationship: contributes_to_morphology_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0007324 {source="FMA"} ! pancreatic lobule property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001264 name: pancreas namespace: uberon def: "An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]." [GO:0031016] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core xref: AAO:0010112 xref: BTO:0000988 xref: CALOHA:TS-0736 xref: EFO:0000855 xref: EHDAA2:0001367 xref: EHDAA:6893 xref: EMAPA:17503 xref: EV:0100092 xref: FMA:7198 xref: GAID:334 xref: galen:Pancreas xref: MA:0000120 xref: MAT:0000075 xref: MESH:D010179 xref: MIAA:0000075 xref: NCIT:C12393 xref: SCTID:181277001 xref: TAO:0000140 xref: UMLS:C0030274 {source="ncithesaurus:Pancreas"} xref: VHOG:0000050 xref: Wikipedia:Pancreas xref: XAO:0000136 xref: ZFA:0000140 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002075 ! viscus relationship: has_developmental_contribution_from UBERON:0003923 {source="Wikipedia"} ! dorsal pancreatic bud relationship: has_developmental_contribution_from UBERON:0003924 {source="Wikipedia"} ! ventral pancreatic bud relationship: has_part UBERON:0000016 ! endocrine pancreas relationship: has_part UBERON:0000017 {gci_relation="part_of", gci_filler="NCBITaxon:89593"} ! exocrine pancreas relationship: only_in_taxon NCBITaxon:7742 {source="PMID:16417468"} ! Vertebrata property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/7e/Blausen_0699_PancreasAnatomy2.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Organ which secretes a fluid containing enzymes that aid in the digestion of food.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010112", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "In the hagfish and lampreys (our most primitive vertebrate species of today), the first sign of 'a new organ' is found as collections of endocrine cells around the area of the bile duct connection with the duodenum. These endocrine organs are composed of 99% beta cells and 1% somatostatin-producing delta cells. Compared to the more primitive protochordates (e.g. amphioxus), this represents a stage where all previously scattered insulin-producing cells of the intestinal tissue have now quantitatively migrated to found a new organ involved in sensing blood glucose rather than gut glucose. Only later in evolution, the beta cells are joined by exocrine tissue and alpha cells (exemplified by the rat-, rabbit- and elephant-fishes). Finally, from sharks and onwards in evolution, we have the islet PP-cell entering to complete the pancreas.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000050", ontology="VHOG", source="DOI:10.1016/j.crvi.2007.03.006 Madsen OD, Pancreas phylogeny and ontogeny in relation to a 'pancreatic stem cell'. C.R. Biologies (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "pancreatic" xsd:string property_value: UBPROP:0000008 "As a secretory organ serving exocrine and endocrine functions, the pancreas is specific to the vertebrates[PMID:16417468] Hagfishes and lampreys are unique in the complete separation of their endocrine pancreas (islet or- gan) and their exocrine pancreas (50). The endocrine and exocrine pancreas are coassociated in crown gnathostomes (50). In Branchiostoma and Ciona, there is no diverticulum as there is in hagfishes, lampreys, and gnathostomes, only dispersed insulin-secreting cells in the walls of the gastrointestinal tract (51, 52)" xsd:string {source="PMID:20959416"} property_value: UBPROP:0000008 "The zebrafish does not have a discrete pancreas. Exocrine pancreatic tissue can be found scattered along the intestinal tract. The acinar structure of the exocrine pancreas is very similar to that of mammals and comprises cells with a very dark, basophilic cytoplasm" xsd:string property_value: UBPROP:0000009 "The mature pancreas of higher vertebrates and mammals comprises two major functional units: the exocrine pancreas, which is responsible for the production of digestive enzymes to be secreted into the gut lumen, and the endocrine pancreas, which has its role in the synthesis of several hormones with key regulatory functions in food uptake and metabolism. The exocrine portion constitutes the majority of the mass of the pancreas, and contains only two different cell types, the secretory acinar cells and the ductular cells. The endocrine portion, which comprises only 1-2% of the total mass, contains five different cell types, which are organized into mixed functional assemblies referred to as the islets of Langerhans" xsd:string {source="PMID:16417468"} [Term] id: UBERON:0001265 name: trabecula of spleen namespace: uberon def: "A trabecula that is part of a spleen." [OBOL:automatic] subset: human_reference_atlas synonym: "spleen trabeculum" EXACT [] synonym: "splenic trabecula" EXACT [] synonym: "trabeculae of spleen" EXACT PLURAL [] xref: EMAPA:35808 xref: FMA:16027 xref: MA:0000758 xref: NCIT:C33607 xref: SCTID:61987002 xref: UMLS:C0229688 {source="ncithesaurus:Splenic_Trabecula"} xref: Wikipedia:Trabeculae_of_spleen is_a: UBERON:0000440 ! trabecula is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000440 ! trabecula intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:1000024 {source="FMA"} ! parenchyma of spleen property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001268 name: peritoneal fluid namespace: uberon def: "Transudate contained in the peritoneal cavity." [FMA:16515] subset: pheno_slim subset: uberon_slim xref: BTO:0001031 xref: EMAPA:35683 xref: FMA:16515 xref: MA:0002531 xref: ncithesaurus:Peritoneal_Fluid xref: Wikipedia:Peritoneal_fluid is_a: UBERON:0007779 ! transudate is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland is_a: UBERON:0036217 ! coelomic fluid intersection_of: UBERON:0007779 ! transudate intersection_of: located_in UBERON:0001179 ! peritoneal cavity relationship: located_in UBERON:0001179 ! peritoneal cavity [Term] id: UBERON:0001269 name: acetabular part of hip bone namespace: uberon def: "The acetabulum is a concave surface of the pelvis. The head of the femur meets with the pelvis at the acetabulum, forming the hip joint. There are three bones of the os coxae (hip bone) that come together to form the acetabulum. Contributing a little more than two-fifths of the structure is the ischium, which provides lower and side boundaries to the acetabulum. The ilium forms the upper boundary, providing a little less than two-fifths of the structure of the acetabulum. The rest is formed by the pubis, near the midline. It is bounded by a prominent uneven rim, which is thick and strong above, and serves for the attachment of the acetabular labrum, which reduces its opening, and deepens the surface for formation of the hip joint. At the lower part of the acetabulum is the acetabular notch, which is continuous with a circular depression, the acetabular fossa, at the bottom of the cavity of the acetabulum. The rest of the acetabulum is formed by a curved, crescent-moon shaped surface, the lunate surface, where the joint is made with the head of the femur. Its counterpart in the pectoral girdle is the glenoid fossa.[WP,unvetted]." [Wikipedia:Acetabulum] subset: pheno_slim subset: uberon_slim synonym: "acetabular region" EXACT [VHOG:0000974] synonym: "acetabulum" EXACT [MA:0001335] xref: AAO:0000770 xref: EHDAA:10661 xref: EMAPA:18346 xref: FMA:16579 xref: GAID:206 xref: MA:0001335 xref: MESH:D000077 xref: NCIT:C32042 xref: RETIRED_EHDAA2:0001427 xref: SCTID:182027007 xref: UMLS:C0000962 {source="ncithesaurus:Acetabulum"} xref: VHOG:0000974 xref: Wikipedia:Acetabulum is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0001273 {source="Phenoscape"} ! ilium relationship: part_of UBERON:0001486 {source="FMA"} ! hip joint property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Illu_pelvic_girdle.jpg" xsd:anyURI property_value: UBPROP:0000001 "Cavity for the articulation of the proximal bone of the hind limb.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000770", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "During the transformation from the osteolepiform fins to tetrapod limbs, the appendages and girdles underwent a number of radical changes. The pelvic girdle became a weight-bearing structure by evolution of an ischium, a full mesio-ventral contact between the two sides of the girdle, an ilium, and a contact between the vertebral column and the girdle through a sacral rib. Fore- and hindlimbs shifted laterally by reorientation of the glenoid and the acetabulum.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000974", ontology="VHOG", source="DOI:10.1038/nature04119 Boisvert CA, The pelvic fin and girdle of Panderichthys and the origin of tetrapod locomotion. Nature (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In reptiles and in birds, the acetabula are deep sockets." xsd:string {source="WP"} property_value: UBPROP:0000012 "whilst WP defines this as a surface, MA treats it as a bone. There are other FMA classes that may be better suited to representing the surface." xsd:string {external_ontology="MA"} [Term] id: UBERON:0001270 name: bony pelvis namespace: uberon def: "A ring of bone formed by the sacrum and the first few coccygeal vertebrae as the roof, the pubis and ischia as the floor and the ilia and the acetabular part of the ischia as the walls." [http://medical-dictionary.thefreedictionary.com/bony+pelvis] synonym: "pelvis ossea" EXACT [] synonym: "skeletal system of pelvis" EXACT [FMA:16580] xref: FMA:16580 xref: SCTID:46633002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system disjoint_from: UBERON:0002355 ! pelvic region of trunk relationship: has_part UBERON:0001274 ! ischium relationship: has_part UBERON:0001275 ! pubis relationship: has_part UBERON:0003690 ! fused sacrum property_value: editor_note "TODO add taxon-specific part of relations connecting sub-structures to this." xsd:string property_value: UBPROP:0000012 "in FMA, this is part of the axial skeletal system" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001271 name: pelvic girdle region namespace: uberon def: "The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pelvic girdle regions." [DOI:10.1002/dvdy.22617, FMA:16581, FMA:23217, https://groups.google.com/d/topic/obo-anatomy/h4R4xKmINrw/discussion, https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: uberon_slim subset: vertebrate_core synonym: "girdle - pelvic" RELATED [] synonym: "pelvic girdle" RELATED INCONSISTENT [] xref: EMAPA:37862 {source="MA:th"} xref: FMA:16581 xref: NCIT:C33291 xref: SCTID:360010001 xref: UMLS:C0684083 {source="ncithesaurus:Pelvic_Girdle"} xref: VSAO:0000304 is_a: UBERON:0007823 ! appendage girdle region is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0007823 ! appendage girdle region intersection_of: part_of UBERON:0010709 ! pelvic complex disjoint_from: UBERON:0007832 ! pelvic girdle skeleton relationship: has_skeleton UBERON:0007832 ! pelvic girdle skeleton relationship: in_lateral_side_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0010709 ! pelvic complex property_value: IAO:0000232 "this class describes the subdivision of the limb/fin, NOT the skeleton within. See also: skeleton of pectoral girdle (UBERON:0007831). See also comments on obo-anatomy mail list. Note that even though the class includes soft tissue it is more restrictive than 'pelvis' which also includes structures in cavities etc. TODO this needs to be better documented" xsd:string property_value: UBPROP:0000001 "Subdivision of lower limb or fin which links the limb/fin to the body[FMA,modified]. There is only one instance of the pelvic girdle region per organism.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000304", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"} [Term] id: UBERON:0001272 name: innominate bone namespace: uberon def: "A fused bone consisting of the ilium, ischium and pubis. Together with the sacrum and coccyx, it comprises the pelvis. [WP,modified]." [https://github.com/obophenotype/uberon/issues/290, https://orcid.org/0000-0002-6601-2165, Wikipedia:Hip_bone] subset: human_reference_atlas subset: uberon_slim synonym: "basipterygium" RELATED [] synonym: "bone of pelvic girdle" BROAD [FMA:16585] synonym: "coxal bone" EXACT [FMA:16585] synonym: "hip bone" EXACT [FMA:16585] synonym: "innominate" BROAD [] synonym: "innominate bone" EXACT [FMA:16585] synonym: "os coxa" EXACT LATIN [] synonym: "os coxae" EXACT LATIN [FMA:16585, FMA:TA] synonym: "os innominatum" RELATED LATIN [Wikipedia:Hip_bone] synonym: "pelvic bone" EXACT [FMA:16585] xref: FMA:16585 xref: GAID:205 xref: SCTID:361776002 xref: Wikipedia:Hip_bone is_a: UBERON:0007830 ! pelvic girdle bone/zone is_a: UBERON:0010428 {source="FMA"} ! flat bone is_a: UBERON:0015212 ! lateral structure relationship: in_lateral_side_of UBERON:0007832 ! pelvic girdle skeleton relationship: part_of UBERON:0001464 {source="FMA"} ! hip property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray341.png" xsd:anyURI property_value: editor_note "currently this class is restricted to exclude the teleost bone as the definition mentions ilium, ischium and pubis. In future we may add a grouping class for girdle bones that supports the appendage" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "The hip/pelvic bone/basipterygium first appears in fishes, where it consists of a simple, usually triangular bone, to which the pelvic fin articulates. The hip bones on each side usually connect with each other at the forward end, and are even solidly fused in lungfishes and sharks, but they never attach to the vertebral column" xsd:string {source="WP"} property_value: UBPROP:0000012 "in FMA this is a paired structure. NCITA has 'pelvic bone' but this is the *superclass* of ilium/ischium/pubis. The MA class 'pelvis bone' is actually a superclass of 'pelvic girdle bone' and caudal/sacral vertebra." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001273 name: ilium namespace: uberon def: "Paired endochondral bone that is the dorsal-most of the pelvic bones, offering attachment areas for gluteal muscles on its main surface [PHENOSCAPE:ad]." [https://github.com/obophenotype/uberon/issues/105, https://github.com/obophenotype/uberon/issues/60, PHENOSCAPE:ad] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "iliac bone" EXACT [EMAPA:18726] synonym: "ilium bone" EXACT [] synonym: "illium" RELATED [] synonym: "os iliacum" EXACT [] synonym: "os ilii" EXACT [] synonym: "os ilium" EXACT LATIN [FMA:16589, FMA:TA] xref: AAO:0000772 xref: CALOHA:TS-2200 xref: EFO:0003049 xref: EMAPA:18726 xref: FMA:16589 xref: GAID:207 xref: galen:Ilium xref: MA:0001336 xref: MESH:D007085 xref: NCIT:C32765 xref: SCTID:182029005 xref: UMLS:C0020889 {source="ncithesaurus:Ilium"} xref: Wikipedia:Ilium_(bone) is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0007830 ! pelvic girdle bone/zone is_a: UBERON:0015054 ! iliac endochondral element is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0015054 ! iliac endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: contributes_to_morphology_of UBERON:0007830 ! pelvic girdle bone/zone relationship: develops_from UBERON:0010714 {source="cjm"} ! iliac cartilage element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: in_lateral_side_of UBERON:0007832 ! pelvic girdle skeleton relationship: part_of UBERON:0001272 {source="FMA"} ! innominate bone property_value: RO:0002161 NCBITaxon:32443 {source="Wikipedia"} property_value: RO:0002174 NCBITaxon:8570 {source="Wikipedia"} property_value: UBPROP:0000001 "Paired, rodlike endochondral bones that constitute the anterior pelvic girdle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000772", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000007 "iliac" xsd:string property_value: UBPROP:0000008 "All reptiles have an ilium except snakes, although some snake species have a tiny bone which is considered to be an ilium" xsd:string {source="WP"} property_value: UBPROP:0000012 "this is_a hip bone in MA." xsd:string {external_ontology="MA"} [Term] id: UBERON:0001274 name: ischium namespace: uberon def: "Endochondral bone that is paired, forming the posterior part of the pelvis, articulating with the pubis and ilium." [VSAO:0005006, VSAO:NI, Wikipedia:Ischium] subset: pheno_slim subset: uberon_slim synonym: "ischial bone" EXACT [EMAPA:18727] synonym: "ischium bone" EXACT [] synonym: "os ischii" RELATED LATIN [AAO:0000860, Wikipedia:Ischium] xref: AAO:0000860 xref: EMAPA:18727 xref: FMA:16592 xref: GAID:208 xref: galen:Ischium xref: MA:0001337 xref: MESH:D007512 xref: NCIT:C32884 xref: SCTID:182025004 xref: UMLS:C0022122 {source="ncithesaurus:Ischium"} xref: VSAO:0005006 xref: Wikipedia:Ischium is_a: UBERON:0002513 {source="VSAO"} ! endochondral bone is_a: UBERON:0007830 {source="MA"} ! pelvic girdle bone/zone is_a: UBERON:0008202 {source="MA"} ! bone of hip region is_a: UBERON:0015056 ! ischial endochondral element is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0015056 ! ischial endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: contributes_to_morphology_of UBERON:0007830 ! pelvic girdle bone/zone relationship: develops_from UBERON:0006254 {source="cjm"} ! ischial cartilage element relationship: in_lateral_side_of UBERON:0007832 ! pelvic girdle skeleton relationship: part_of UBERON:0001272 ! innominate bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Illu_pelvic_girdle.jpg" xsd:anyURI property_value: UBPROP:0000001 "Paired bones of endochondral origin that constitute the posterior elements of the pelvic girdle. They are synostotically fused to each other and form the posterior part of the acetabulum.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000860", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000007 "ischial" xsd:string property_value: UBPROP:0000012 "this is_a hip bone in MA; in FMA it is a zone of bone organ." xsd:string {external_ontology="MA"} [Term] id: UBERON:0001275 name: pubis namespace: uberon def: "A paired endochondral bone making up the anteroventral region of the tripartite pelvic girdle forming part of the ventral edge of the acetabulum. The origin site of many proximal hindlimb muscles. [PHENOSCAPE:ad]." [https://github.com/obophenotype/uberon/issues/68, PHENOSCAPE:ad] subset: pheno_slim subset: uberon_slim synonym: "os pubis" RELATED [Wikipedia:Pubis_(bone)] synonym: "pubic bone" RELATED [Wikipedia:Pubis_(bone)] synonym: "pubis bone" RELATED [Wikipedia:Pubis_(bone)] xref: AAO:0000861 xref: EMAPA:18728 xref: FMA:16595 xref: galen:Pubis xref: MA:0001338 xref: MESH:D011630 xref: NCIT:C33423 xref: SCTID:182035005 xref: UMLS:C0034014 {source="ncithesaurus:Pubic_Bone"} xref: Wikipedia:Pubis_(bone) is_a: UBERON:0002513 {source="VSAO"} ! endochondral bone is_a: UBERON:0007830 {source="MA"} ! pelvic girdle bone/zone is_a: UBERON:0008202 {source="MA"} ! bone of hip region is_a: UBERON:0015055 ! pubic endochondral element is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0015055 ! pubic endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: contributes_to_morphology_of UBERON:0007830 ! pelvic girdle bone/zone relationship: develops_from UBERON:0010718 ! pubic cartilage element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: in_lateral_side_of UBERON:0007832 ! pelvic girdle skeleton relationship: part_of UBERON:0001272 {source="FMA"} ! innominate bone property_value: UBPROP:0000001 "Paired, cartilaginous (ocassionally calcified) elements that form the ventral portion of the pelvic girdle. Each is located ventral to the acetabulum between the anteroventral margin of the ischium and the posteroventral margin of the illium. When the element calcifies or ossifies, its articulation with adjacent elements is difficult to distinguish. Both pubes are synchondrotically fused to one another.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000861", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000012 "isa bone zone in FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001276 name: epithelium of stomach namespace: uberon def: "The epithelial layer of the stomach ." [MP:0000471] subset: pheno_slim synonym: "epithelial tissue of stomach" EXACT [OBOL:automatic] synonym: "epithelial tissue of ventriculus" EXACT [OBOL:automatic] synonym: "epithelium of ventriculus" EXACT [OBOL:automatic] synonym: "gastric epithelium" RELATED [BTO:0000500] synonym: "stomach epithelial tissue" EXACT [OBOL:automatic] synonym: "stomach epithelium" EXACT [OBOL:automatic] synonym: "ventriculus epithelial tissue" EXACT [OBOL:automatic] synonym: "ventriculus epithelium" EXACT [OBOL:automatic] xref: BTO:0000500 xref: CALOHA:TS-2068 xref: EHDAA2:0001918 xref: EMAPA:17023 xref: FMA:17091 xref: MA:0001610 xref: SCTID:64977002 xref: VHOG:0001433 is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0004808 ! gastrointestinal system epithelium is_a: UBERON:0015833 ! foregut epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000945 ! stomach relationship: contributes_to_morphology_of UBERON:0001199 ! mucosa of stomach relationship: part_of UBERON:0001199 ! mucosa of stomach property_value: UBPROP:0000012 "in FMA this is classified as simple columnar, MA divides this into squamous and glandular" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001277 name: intestinal epithelium namespace: uberon def: "Epithelial layer that lines the intestine." [UBERON:cjm] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "bowel epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of bowel" EXACT [OBOL:automatic] synonym: "epithelial tissue of intestine" EXACT [OBOL:automatic] synonym: "epithelium of bowel" EXACT [OBOL:automatic] synonym: "epithelium of intestine" EXACT [OBOL:automatic] synonym: "intestine epithelial tissue" EXACT [OBOL:automatic] synonym: "intestine epithelium" RELATED [] synonym: "villous epithelium" NARROW [ZFA:0005124] xref: BTO:0000781 xref: EMAPA:32873 xref: FMA:17229 xref: MA:0001536 xref: NCIT:C49240 xref: SCTID:266135004 xref: TAO:0005124 xref: UMLS:C0226890 {source="ncithesaurus:Intestinal_Epithelium"} xref: Wikipedia:Intestinal_epithelium xref: ZFA:0005124 is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0004808 ! gastrointestinal system epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000160 ! intestine relationship: contributes_to_morphology_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001242 ! intestinal mucosa property_value: UBPROP:0000001 "Simple columnar epithelium that lines the intestine, sometimes pseudostratified, with absorptive brush-border cells and mucous goblet cells clearly visible. Crosnier et al. 2005[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005124", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001278 name: epithelium of large intestine namespace: uberon def: "An epithelium that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of large intestine" EXACT [OBOL:automatic] synonym: "large intestinal epithelium" EXACT [] synonym: "large intestine epithelial tissue" EXACT [OBOL:automatic] synonym: "large intestine epithelium" EXACT [] xref: CALOHA:TS-2105 xref: EMAPA:35466 xref: FMA:17301 xref: MA:0001545 is_a: UBERON:0001277 ! intestinal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001207 ! mucosa of large intestine [Term] id: UBERON:0001279 name: portal triad namespace: uberon def: "A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel." [http://orcid.org/0000-0002-6601-2165, ISBN:0-683-40008-8, MGI:csmith, MP:0008993] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "trias hepatica" EXACT [] synonym: "trias hepatica" RELATED LATIN [Wikipedia:Portal_triad] xref: FMA:17523 xref: MA:0002499 xref: NCIT:C33342 xref: SCTID:362192000 xref: UMLS:C0227514 {source="ncithesaurus:Portal_Triad"} xref: Wikipedia:Portal_triad is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0034921 ! multi organ part structure relationship: contributes_to_morphology_of UBERON:0001171 ! portal lobule relationship: has_part UBERON:0001193 ! hepatic artery relationship: has_part UBERON:0002017 ! portal vein relationship: has_part UBERON:0003704 ! intrahepatic bile duct relationship: part_of UBERON:0001172 ! hepatic acinus property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/62/Portal_triad.JPG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000013 "The misnomer 'portal triad' traditionally has included only the first three structures, and was named before lymphatic vessels were discovered in the structure. It can refer both to the largest branch of each of these vessels running inside the hepatoduodenal ligament, and to the smaller branches of these vessels inside the liver." xsd:string [Term] id: UBERON:0001280 name: liver parenchyma namespace: uberon alt_id: UBERON:0003223 def: "The functional units of the liver including the lobules." [MP:0008986] subset: pheno_slim synonym: "hepatic parenchyma" EXACT [FMA:17540] synonym: "hepatic parenchyme" RELATED [VHOG:0000539] synonym: "liver parenchyme" EXACT [XAO:0000454] synonym: "parenchyma of liver" EXACT [FMA:17540] xref: AAO:0010405 xref: EHDAA2:0001004 xref: EHDAA:2201 xref: EMAPA:17203 xref: FMA:17540 xref: MA:0000366 xref: NCIT:C32735 xref: SCTID:363535004 xref: UMLS:C0736268 xref: VHOG:0000539 xref: XAO:0000454 is_a: UBERON:0000353 ! parenchyma is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002107 ! liver relationship: contributes_to_morphology_of UBERON:0002107 ! liver relationship: develops_from UBERON:0008835 {source="XAO"} ! hepatic diverticulum relationship: part_of UBERON:0002107 ! liver property_value: UBPROP:0000003 "the (liver) tubular structure (dual layered parenchyma) appears to be conserved among all embryonic vertebrates (...) it is not unlikely that all vertebrate livers share the same fundamental functional unit.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000539", ontology="VHOG", source="DOI:10.1002/ar.20524 Hardman RC, Volz DC, Kullman SW, Hinton DE, An in vivo look at vertebrate liver architecture: three-dimensional reconstruction from Medaka (Oryzias latipes). The Anatomical Record (2007)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001281 name: hepatic sinusoid namespace: uberon alt_id: UBERON:0003275 def: "Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers." [Wikipedia:Hepatic_sinusoid, ZFIN:curator] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "hepatic sinusoids" RELATED [] synonym: "liver hepatic sinusoids" EXACT [EHDAA2:0000999] synonym: "liver sinusoid" EXACT [] synonym: "liver sinusoidal blood vessel" EXACT [OBOL:automatic] synonym: "sinusoid of liver" EXACT [OBOL:automatic] synonym: "sinusoidal blood vessel of liver" EXACT [OBOL:automatic] synonym: "vas capillare sinusoideum" EXACT [] synonym: "vas sinusoideum" EXACT LATIN [Wikipedia:Hepatic_sinusoid] xref: EHDAA2:0000999 xref: EMAPA:17365 xref: FMA:17543 xref: MA:0000367 xref: NCIT:C32733 xref: SCTID:67435004 xref: TAO:0005091 xref: UMLS:C0227523 {source="ncithesaurus:Hepatic_Sinusoid"} xref: VHOG:0000708 xref: Wikipedia:Hepatic_sinusoid xref: ZFA:0005091 is_a: UBERON:0003909 ! sinusoid is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0015796 ! liver blood vessel intersection_of: UBERON:0003909 ! sinusoid intersection_of: part_of UBERON:0002107 ! liver relationship: connected_to UBERON:0006841 ! central vein of liver relationship: contributes_to_morphology_of UBERON:0004647 ! liver lobule relationship: develops_in UBERON:0001113 ! lobe of liver relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0004647 ! liver lobule relationship: part_of UBERON:0006877 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! vasculature of liver property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "(...) the amphibian liver has characteristics in common with both fish and terrestrial vertebrates. (...) The histological structure of the liver is similar to that in other vertebrates, with hepatocytes arranged in clusters and cords separated by a meshwork of sinusoids and the presence of the traditional triad of portal venule, hepatic arteriole, and bile duct.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000708", ontology="VHOG", source="DOI:10.1053/ax.2000.7133 Crawshaw GJ, Weinkle TK, Clinical and pathological aspects of the amphibian liver. Seminars in Avian and Exotic Pet Medicine (2000)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001282 name: intralobular bile duct namespace: uberon def: "The tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule." [MGI:csmith, MP:0009499] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "canal of Hering" RELATED [] synonym: "canal of Herring" EXACT [FMA:17545] synonym: "canals of Hering" RELATED PLURAL [Wikipedia:Canals_of_Hering] synonym: "cholangiole" EXACT [FMA:17545] synonym: "duct of Herring" RELATED [Wikipedia:Canals_of_Hering] synonym: "ductus interlobularis bilifer" EXACT LATIN [FMA:17545, FMA:TA] synonym: "intrahepatic bile ductule" RELATED [Wikipedia:Canals_of_Hering] xref: FMA:17545 xref: MA:0002669 xref: NCIT:C32255 xref: SCTID:227002 xref: SCTID:269922006 xref: UMLS:C0227517 {source="ncithesaurus:Canal_of_Hering"} xref: Wikipedia:Canals_of_Hering is_a: UBERON:0003704 {source="FMA"} ! intrahepatic bile duct is_a: UBERON:0014716 ! interlobular duct relationship: contributes_to_morphology_of UBERON:0004647 ! liver lobule relationship: has_part CL:0000182 ! hepatocyte relationship: has_part CL:1000488 ! cholangiocyte relationship: part_of UBERON:0001172 {source="FMA"} ! hepatic acinus relationship: part_of UBERON:0004647 {source="FMA"} ! liver lobule property_value: editor_note "Note that this is part of the intrahepatic bile duct in MA, as this class is more alike the tree in FMA. Note also that SCT has canal of Hering and Entire IBduct as the only sibling terms under 'Structure of intralobular bile duct' (i.e. the CoH is the only part of the entire IBduct)" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001285 name: nephron namespace: uberon def: "The basic functional unit of the kidney. its chief function is to regulate the concentration of water and soluble substances like sodium salts by filtering the blood, reabsorbing what is needed and excreting the rest as urine. A nephron eliminates wastes from the body, regulates blood volume and blood pressure, controls levels of electrolytes and metabolites, and regulates blood pH. Its functions are vital to life and are regulated by the endocrine system by hormones such as antidiuretic hormone, aldosterone, and parathyroid hormone.[WP]." [PMID:9268568, Wikipedia:Nephron] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mature nephron" NARROW [EMAPA:28491] synonym: "nephroneum" RELATED LATIN [Wikipedia:Nephron] synonym: "tubulus renalis" RELATED LATIN [Wikipedia:Nephron] xref: BTO:0000924 xref: CALOHA:TS-1312 xref: EMAPA:28491 xref: EMAPA:35592 xref: EV:0100384 xref: FMA:17640 xref: GAID:428 xref: MA:0000375 xref: MESH:D009399 xref: NCIT:C13048 xref: SCTID:361337001 xref: TAO:0002153 xref: UMLS:C0027713 {source="ncithesaurus:Nephron"} xref: Wikipedia:Nephron xref: ZFA:0005282 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000064 ! organ part relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: develops_from UBERON:0010532 ! primitive nephron relationship: immediate_transformation_of UBERON:0010532 {source="Bgee:AN"} ! primitive nephron relationship: part_of UBERON:0007684 {source="FMA"} ! uriniferous tubule property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png" xsd:anyURI property_value: editor_note "kidney terms require review for cross-vertebrate compatibility and developmental relationships." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Functional unit of the kidney that filters waste.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002153", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000008 "In the avian kidney, three types of nephron are identified: mammalian-type nephrons with long and short loops of Henle, and reptilian type nephrons (Gambaryan, 1992)" xsd:string {source="GO"} [Term] id: UBERON:0001295 name: endometrium namespace: uberon def: "The glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy." [MESH:A05.360.319.679.490, MGI:smb, MP:0004896] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "tunica mucosa (endometrium)" EXACT [FMA:17742] synonym: "tunica mucosa uteri" EXACT LATIN [Wikipedia:Endometrium] synonym: "uterine endometrium" EXACT [BTO:0001422] synonym: "uterine mucosa" RELATED [] synonym: "uterine mucous membrane" RELATED [BTO:0001422] xref: BTO:0001422 xref: CALOHA:TS-0276 xref: EFO:0000980 xref: EMAPA:29917 xref: EV:0100115 xref: FMA:17742 xref: GAID:377 xref: MA:0000390 xref: MAT:0000319 xref: MESH:D004717 xref: MIAA:0000319 xref: NCIT:C12313 xref: SCTID:278867007 xref: UMLS:C0014180 {source="ncithesaurus:Endometrium"} xref: VHOG:0001285 xref: Wikipedia:Endometrium is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0019042 ! reproductive system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000995 ! uterus relationship: contributes_to_morphology_of UBERON:0000995 ! uterus relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0000459 {source="FMA"} ! uterine wall property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The mucous membrane lining the uterus. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001285", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Endometrium"} property_value: UBPROP:0000003 "The maternal part of the placenta (of eutherian mammals) is the vascularized and glandular uterine lining, or endometrium.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001285", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.144", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "endometrial" xsd:string property_value: UBPROP:0000008 "Animals that have estrous cycles reabsorb the endometrium if conception does not occur during that cycle. Animals that have menstrual cycles shed the endometrium through menstruation instead" xsd:string property_value: UBPROP:0000012 "in FMA this is subdivided into basal and outer" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001297 name: serosa of uterus namespace: uberon def: "Outer serosa layer of the uterus." [Wikipedia:Perimetrium] synonym: "perimetrium" EXACT [Wikipedia:Perimetrium] synonym: "serous coat of uterus" EXACT [Wikipedia:Perimetrium] synonym: "serous membrane of uterus" EXACT [OBOL:automatic] synonym: "tunica serosa (perimetrium)" EXACT [] synonym: "tunica serosa uteri" EXACT LATIN [FMA:17744, FMA:TA] synonym: "uterine serosa" EXACT [] synonym: "uterus serosa" EXACT [] synonym: "uterus serous membrane" EXACT [OBOL:automatic] synonym: "visceral peritoneum of uterus" EXACT [] xref: EMAPA:37792 {source="MA:th"} xref: FMA:17744 xref: MA:0001729 xref: NCIT:C33298 xref: SCTID:253705006 xref: UMLS:C0227824 {source="ncithesaurus:Perimetrium"} xref: Wikipedia:Perimetrium is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000459 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! uterine wall property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI property_value: editor_note "TODO - check for parallel structure with peritoneum" xsd:string [Term] id: UBERON:0001299 name: glans penis namespace: uberon def: "The conic expansion of the corpus spongiosum that forms the head of the penis." [MGI:anna, MP:0009102] subset: pheno_slim subset: uberon_slim synonym: "balanus" RELATED [BTO:0003118] synonym: "coronal sulcus" RELATED INCONSISTENT [Wikipedia:Glans_penis] synonym: "glans" BROAD [EV:0100108] xref: BTO:0003118 xref: EMAPA:18988 xref: EV:0100108 xref: FMA:18247 xref: GAID:0000012 xref: MA:0002726 xref: NCIT:C12324 xref: SCTID:263378009 xref: UMLS:C0227948 {source="ncithesaurus:Glans_Penis"} xref: VHOG:0001475 xref: Wikipedia:Glans_penis is_a: UBERON:0035651 ! glans intersection_of: UBERON:0035651 ! glans intersection_of: part_of UBERON:0000989 ! penis relationship: contributes_to_morphology_of UBERON:0000989 ! penis relationship: develops_from UBERON:0013239 ! future glans penis relationship: immediate_transformation_of UBERON:0013239 {source="Bgee:AN"} ! future glans penis relationship: part_of UBERON:0000989 ! penis relationship: sexually_homologous_to UBERON:0006653 ! glans clitoris property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/13/Anteriorglanspenis.jpg" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI [Term] id: UBERON:0001301 name: epididymis namespace: uberon def: "The elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens." [MGI:pvb, MP:0002631] subset: efo_slim subset: pheno_slim subset: uberon_slim xref: BTO:0000408 xref: CALOHA:TS-0285 xref: EFO:0000982 xref: EMAPA:19290 xref: EV:0100103 xref: FMA:18255 xref: GAID:397 xref: galen:Epididymis xref: MA:0000397 xref: MAT:0000130 xref: MESH:D004822 xref: MIAA:0000130 xref: NCIT:C12328 xref: SCTID:181432000 xref: UMLS:C0014533 {source="ncithesaurus:Epididymis"} xref: VHOG:0001265 xref: Wikipedia:Epididymis is_a: UBERON:0000025 ! tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005904 ! duct of male reproductive system relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0006946 ! efferent duct relationship: channels_into UBERON:0001000 ! vas deferens relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia relationship: develops_from UBERON:0003074 {source="Wikipedia"} ! mesonephric duct relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0006947 {source="FMA"} ! male genital duct property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_testis_surface.jpg" xsd:anyURI property_value: editor_note "Kardong has epididymis in elasmobranch" xsd:string property_value: UBPROP:0000007 "epididymal" xsd:string property_value: UBPROP:0000008 "A similar, but probably non-homologous, structure is found in cartilaginous fishes" xsd:string {source="WP"} property_value: UBPROP:0000010 "Typically divided into three main regions. In reptiles, there is an additional canal between the testis and the head of the epididymis, which receives the various efferent ducts. This is, however, absent in all birds and mammals. The epididymis is covered by a two layered pseudostratified epithelium. The epithelium is separated by a basement membrane from the connective tissue wall which has smooth muscle cells." xsd:string [Term] id: UBERON:0001302 name: right uterine tube namespace: uberon def: "A fallopian tube that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "right fallopian tube" EXACT [] synonym: "right oviduct" EXACT [] xref: EMAPA:37369 {source="MA:th"} xref: FMA:18483 xref: MA:0001717 xref: NCIT:C33475 xref: SCTID:280106006 xref: UMLS:C0227900 {source="ncithesaurus:Right_Fallopian_Tube"} is_a: UBERON:0003889 ! fallopian tube intersection_of: UBERON:0003889 ! fallopian tube intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI property_value: UBPROP:0000008 "non-functional in monotremes[ISBN:978-0226870137]" xsd:string [Term] id: UBERON:0001303 name: left uterine tube namespace: uberon def: "A fallopian tube that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] synonym: "left fallopian tube" EXACT [] synonym: "left oviduct" EXACT [] xref: EMAPA:37368 {source="MA:th"} xref: FMA:18484 xref: MA:0001716 xref: NCIT:C32959 xref: SCTID:280107002 xref: UMLS:C0227902 {source="ncithesaurus:Left_Fallopian_Tube"} is_a: UBERON:0003889 ! fallopian tube intersection_of: UBERON:0003889 ! fallopian tube intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0001308 name: external iliac artery namespace: uberon def: "The external iliac artery is a large artery in the pelvic region that carries blood to the lower limb. The external iliac artery is a paired artery, meaning there is one on each side of the body: a right external iliac artery and left external iliac artery. The external iliac artery is accompanied by the external iliac vein, which is located posterior to the artery. [WP,unvetted]." [Wikipedia:External_iliac_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria iliaca externa" RELATED LATIN [Wikipedia:External_iliac_artery] xref: BTO:0004666 xref: EHDAA2:0000463 xref: EHDAA:4337 xref: EMAPA:17614 xref: FMA:18805 xref: galen:ExternalIliacArtery xref: MA:0001973 xref: NCIT:C32558 xref: SCTID:181352000 xref: UMLS:C0226398 {source="ncithesaurus:External_Iliac_Artery"} xref: Wikipedia:External_iliac_artery is_a: UBERON:0005609 {source="MA"} ! iliac artery relationship: part_of UBERON:0001191 ! common iliac artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3e/Gray539.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001309 name: internal iliac artery namespace: uberon def: "The internal iliac artery (formerly known as the hypogastric artery) is the main artery of the pelvis. [WP,unvetted]." [Wikipedia:Internal_iliac_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria iliaca interna" RELATED LATIN [Wikipedia:Internal_iliac_artery] synonym: "hypogastric artery" RELATED [BTO:0004667] xref: BTO:0004667 xref: EMAPA:17860 xref: FMA:18808 xref: galen:InternalIliacArtery xref: MA:0001974 xref: NCIT:C32845 xref: SCTID:181346001 xref: UMLS:C0226364 {source="ncithesaurus:Internal_Iliac_Artery"} xref: Wikipedia:Internal_iliac_artery is_a: UBERON:0005609 {source="MA"} ! iliac artery relationship: part_of UBERON:0001191 ! common iliac artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d3/Iliac_artery_bifurcation.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001310 name: umbilical artery namespace: uberon def: "The umbilical artery is a paired artery (with one for each half of the body) that is found in the abdominal and pelvic regions. In the fetus, it extends into the umbilical cord. [WP,unvetted]." [https://github.com/obophenotype/uberon/issues/328, Wikipedia:Umbilical_artery] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "a. umbilicalis" RELATED LATIN [Wikipedia:Umbilical_artery] xref: BTO:0000841 xref: CALOHA:TS-1077 xref: EHDAA:1026 xref: EHDAA:410 xref: EMAPA:16331 xref: EMAPA:16372 xref: FMA:18820 xref: GAID:516 xref: MA:0002072 xref: MESH:D014469 xref: NCIT:C33827 xref: RETIRED_EHDAA2:0002106 xref: SCTID:261404000 xref: UMLS:C0041632 {source="ncithesaurus:Umbilical_Artery"} xref: Wikipedia:Umbilical_artery is_a: UBERON:0001637 ! artery is_a: UBERON:0010260 ! umbilical blood vessel property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Gray502.png" xsd:anyURI property_value: editor_note "todo - compare with EHDAA2. Check embryonic vs extraembryonic, developmental relationships" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/328" xsd:anyURI [Term] id: UBERON:0001312 name: superior vesical artery namespace: uberon def: "An artery that supplies blood to the upper urinary bladder." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim synonym: "arteria vesicali superior" EXACT LATIN [Wikipedia:Superior_vesical_artery] synonym: "arteria vesicalis superior" EXACT LATIN [Wikipedia:Superior_vesical_artery] synonym: "arteriae vesicales superiores" RELATED LATIN [Wikipedia:Superior_vesical_artery] xref: EMAPA:37123 {source="MA:th"} xref: FMA:18839 xref: MA:0002080 xref: NCIT:C52686 xref: SCTID:113268007 xref: UMLS:C0226376 {source="ncithesaurus:Superior_Vesical_Artery"} xref: Wikipedia:Superior_vesical_artery is_a: UBERON:0003468 ! ureteric segment of renal artery is_a: UBERON:0009027 ! vesical artery intersection_of: UBERON:0009027 ! vesical artery intersection_of: supplies UBERON:0000056 ! ureter property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/0/02/Internal_iliac_branches.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000011 "The first part of the superior vesical artery represents the terminal section of the previous portion of the umbilical artery (fetal hypogastric artery)[WP]" xsd:string [Term] id: UBERON:0001314 name: obturator artery namespace: uberon def: "The obturator artery passes antero-inferiorly (forwards and downwards) on the lateral wall of the pelvis, to the upper part of the obturator foramen, and, escaping from the pelvic cavity through the obturator canal, it divides into both an anterior and a posterior branch. [WP,unvetted]." [Wikipedia:Obturator_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria obturatoria" RELATED LATIN [Wikipedia:Obturator_artery] xref: EMAPA:37671 {source="MA:th"} xref: FMA:18865 xref: MA:0002008 xref: NCIT:C33190 xref: SCTID:244302006 xref: UMLS:C0226369 {source="ncithesaurus:Obturator_Artery"} xref: Wikipedia:Obturator_artery is_a: UBERON:0004573 ! systemic artery relationship: branching_part_of UBERON:0001309 ! internal iliac artery relationship: part_of UBERON:0001309 ! internal iliac artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6f/Gray547.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001316 name: external iliac vein namespace: uberon def: "A large vein that connects the femoral vein to the common iliac vein. Their origin is at the inferior margin of the inguinal ligaments and they terminate when they join the internal iliac veins (to form the common iliac veins). Both external iliac veins are accompanied along their course by external iliac arteries. [WP,modified]." [Wikipedia:External_iliac_vein] subset: human_reference_atlas subset: uberon_slim synonym: "vena iliaca externa" RELATED LATIN [Wikipedia:External_iliac_vein] xref: EHDAA2:0000464 xref: EMAPA:37144 {source="MA:th"} xref: FMA:18883 xref: galen:ExternalIliacVein xref: MA:0002144 xref: NCIT:C32560 xref: SCTID:181400000 xref: UMLS:C0226761 {source="ncithesaurus:External_Iliac_Vein"} xref: Wikipedia:External_iliac_vein is_a: UBERON:0005610 {source="MA"} ! iliac vein relationship: connected_to UBERON:0001139 ! common iliac vein relationship: drains UBERON:0002103 ! hindlimb property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/65/Iliac_veins.gif" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001317 name: internal iliac vein namespace: uberon def: "A vein that begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac to form the common iliac vein. [WP,unvetted]." [Wikipedia:Internal_iliac_vein] subset: human_reference_atlas subset: uberon_slim synonym: "hypogastric vein" RELATED [MA:0002139, Wikipedia:Internal_iliac_vein] synonym: "v. hypogastrica" RELATED LATIN [Wikipedia:Internal_iliac_vein] synonym: "v. iliaca interna" RELATED LATIN [Wikipedia:Internal_iliac_vein] xref: EHDAA2:0000874 xref: EMAPA:37148 {source="MA:th"} xref: FMA:18884 xref: galen:InternalIliacVein xref: MA:0002139 xref: MA:0002145 xref: NCIT:C32847 xref: SCTID:181399007 xref: UMLS:C0226764 {source="ncithesaurus:Internal_Iliac_Vein"} xref: VHOG:0000749 xref: Wikipedia:Internal_iliac_vein is_a: UBERON:0005610 {source="MA"} ! iliac vein relationship: connected_to UBERON:0001139 ! common iliac vein relationship: drains UBERON:0005179 ! pelvic region element property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/cb/Internaliliacv.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001322 name: sciatic nerve namespace: uberon def: "A large nerve that supplies nearly the whole of the skin of the leg, the muscles of the back of the thigh, and those of the leg and foot. It begins in the lower back and runs through the buttock and down the lower limb." [Wikipedia:Sciatic_nerve] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "ischiadic nerve" RELATED [Wikipedia:Sciatic_nerve] synonym: "ischiatic nerve" RELATED [Wikipedia:Sciatic_nerve] synonym: "nervus ischiadicus" RELATED LATIN [BTO:0001221, Wikipedia:Sciatic_nerve] synonym: "nervus sciaticus" RELATED [BTO:0001221] xref: BIRNLEX:1133 xref: BTO:0001221 xref: CALOHA:TS-0899 xref: EFO:0001417 xref: EHDAA2:0001779 xref: EHDAA:5659 xref: EMAPA:18577 xref: FMA:19034 xref: GAID:852 xref: MA:0001172 xref: MESH:D012584 xref: NCIT:C52810 xref: SCTID:181050003 xref: UMLS:C0036394 {source="BIRNLEX:1133", source="ncithesaurus:Sciatic_Nerve"} xref: VHOG:0000894 xref: Wikipedia:Sciatic_nerve is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001021 ! nerve relationship: innervates UBERON:0001511 ! skin of leg relationship: overlaps UBERON:0000978 ! leg relationship: part_of UBERON:0001815 ! lumbosacral nerve plexus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3a/Gray1244.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "mouse sciatic nerve origins predominantly from the third lumbar (L3) and L4 spinal nerves, unlike the L4 and L5 in rats - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700063/" xsd:string [Term] id: UBERON:0001323 name: tibial nerve namespace: uberon def: "The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted]." [Wikipedia:Tibial_nerve] subset: uberon_slim synonym: "medial popliteal nerve" EXACT [] synonym: "n. tibialis" RELATED LATIN [Wikipedia:Tibial_nerve] xref: EMAPA:36512 xref: FMA:19035 xref: GAID:854 xref: MA:0001173 xref: MESH:D013979 xref: NCIT:C52809 xref: SCTID:181078002 xref: UMLS:C0040186 {source="ncithesaurus:Tibial_Nerve"} xref: Wikipedia:Tibial_nerve is_a: UBERON:0003431 ! leg nerve relationship: branching_part_of UBERON:0001322 {source="FMA", source="WP"} ! sciatic nerve relationship: part_of UBERON:0001322 ! sciatic nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1a/Gray828.png" xsd:anyURI [Term] id: UBERON:0001325 name: muscle of pelvis namespace: uberon def: "Muscle (organ) which is a part of the pelvis. Examples: levator ani,." [FMA:19086] subset: pheno_slim subset: uberon_slim synonym: "muscle organ of pelvis" EXACT [OBOL:automatic] synonym: "pelvic muscle" EXACT [FMA:19086] synonym: "pelvis muscle" EXACT [] synonym: "pelvis muscle organ" EXACT [OBOL:automatic] xref: EMAPA:18184 xref: EMAPA:37481 {source="MA:th"} xref: FMA:19086 xref: MA:0000534 is_a: UBERON:0003833 {source="MA"} ! abdominal segment muscle is_a: UBERON:0005179 ! pelvic region element intersection_of: UBERON:0014892 {source="FMAdef"} ! skeletal muscle organ intersection_of: part_of UBERON:0002355 {source="FMAdef"} ! pelvic region of trunk [Term] id: UBERON:0001330 name: pampiniform plexus namespace: uberon def: "The pampiniform plexus is a network of many small veins found in the male spermatic cord. It is formed by the union of multiple spermatic veins from the back of the testis and tributaries from the epididymis. The veins of the plexus ascend along the cord in front of the ductus deferens. Below the subcutaneous inguinal ring they unite to form three or four veins, which pass along the inguinal canal, and, entering the abdomen through the abdominal inguinal ring, coalesce to form two veins. These again unite to form a single vein, the testicular vein, which opens on the right side into the inferior vena cava, at an acute angle, and on the left side into the left renal vein, at a right angle. The pampinoform plexus forms the chief mass of the cord. In addition to its function in venous return from the testes, the pampiniform plexus also plays a role in the temperature regulation of the testes. It acts as a heat exchanger, cooling blood in adjacent arteries. An abnormal enlargement of the pampiniform plexus is a medical condition called varicocele. [WP,unvetted]." [Wikipedia:Pampiniform_venous_plexus] subset: human_reference_atlas subset: uberon_slim synonym: "pampiniform venous plexus" EXACT [] synonym: "plexus of veins of fascia of prostate" EXACT [] synonym: "plexus venosus pampiniformis" EXACT LATIN [FMA:19607, FMA:TA] synonym: "venous plexus of fascia of prostate" EXACT [] synonym: "venous plexus of fascia of prostate gland" EXACT [] xref: EMAPA:37385 {source="MA:th"} xref: FMA:19607 xref: MA:0001866 xref: SCTID:279661001 xref: Wikipedia:Pampiniform_venous_plexus is_a: UBERON:0001593 ! venous plexus relationship: connected_to UBERON:0000442 ! right testicular vein relationship: located_in UBERON:0005352 ! spermatic cord relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray1147.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001331 name: skin of penis namespace: uberon def: "A zone of skin that is part of a penis [Automatically generated definition]." [OBOL:automatic] synonym: "penile skin" EXACT [FMA:19638] synonym: "penis skin" EXACT [] synonym: "penis zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of penis" EXACT [OBOL:automatic] xref: EMAPA:35675 xref: FMA:19638 xref: MA:0002727 xref: SCTID:35900000 is_a: UBERON:0000014 ! zone of skin is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000989 ! penis relationship: continuous_with UBERON:0001085 ! skin of trunk relationship: part_of UBERON:0000989 ! penis [Term] id: UBERON:0001333 name: male urethra namespace: uberon def: "A urethra that is part of a male reproductive system." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim xref: BTO:0004089 xref: EMAPA:18692 xref: FMA:19668 xref: MA:0002640 xref: NCIT:C33050 xref: SCTID:264085007 xref: UMLS:C0458452 {source="ncithesaurus:Male_Urethra"} xref: Wikipedia:Male_urethra is_a: UBERON:0000057 ! urethra intersection_of: UBERON:0000057 ! urethra intersection_of: part_of UBERON:0003101 ! male organism relationship: part_of UBERON:0003101 ! male organism property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI [Term] id: UBERON:0001334 name: female urethra namespace: uberon def: "A urethra that is part of a female reproductive system." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "urethra feminina" RELATED [BTO:0004088] synonym: "urethra muliebris" RELATED [BTO:0004088] xref: BTO:0004088 xref: EMAPA:28747 xref: FMA:19669 xref: MA:0002637 xref: NCIT:C32591 xref: SCTID:264469008 xref: UMLS:C0458485 {source="ncithesaurus:Female_Urethra"} xref: Wikipedia:Female_urethra is_a: UBERON:0000057 ! urethra intersection_of: UBERON:0000057 ! urethra intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0003100 ! female organism property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/cb/Female_anatomy.png" xsd:anyURI [Term] id: UBERON:0001338 name: urethral gland namespace: uberon def: "Any of the numerous small mucous-secreting glands located in the wall of the male or female urethra that help protect the epithelium from the corrosive urine." [MP:anna] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "gland of urethra" EXACT [OBOL:automatic] synonym: "urethra gland" EXACT [] synonym: "urethra gland (male or female)" EXACT [] synonym: "urethral mucuous gland" EXACT [] xref: EMAPA:37784 {source="MA:th"} xref: FMA:19683 xref: MA:0001688 xref: SCTID:279477005 is_a: UBERON:0000414 {source="MP"} ! mucous gland is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000057 ! urethra relationship: contributes_to_morphology_of UBERON:0000057 ! urethra relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0000057 ! urethra property_value: UBPROP:0000012 "NCIT:C12339 paraurethral gland belongs here" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0001343 name: seminiferous tubule of testis namespace: uberon def: "The tubules in the testes where spermatogenesis occurs." [https://github.com/obophenotype/uberon/issues/1381, ISBN:0-683-40008-8, MGI:csmith, MP:0002216] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "seminiferous cord" EXACT [EMAPA:18685] synonym: "seminiferous tubule" EXACT [] synonym: "testis - seminiferous tubule" EXACT [] synonym: "tubuli seminiferi" EXACT [] synonym: "tubuli seminiferi" RELATED LATIN [Wikipedia:Seminiferous_tubule] xref: AAO:0010399 xref: BTO:0001235 xref: CALOHA:TS-1239 xref: EFO:0001404 xref: EMAPA:18685 xref: EMAPA:31476 xref: EV:0100380 xref: FMA:19825 xref: GAID:400 xref: MA:0000412 xref: MAT:0000503 xref: MESH:D012671 xref: NCIT:C13047 xref: NCIT:C34293 xref: SCTID:279614002 xref: UMLS:C0036630 {source="ncithesaurus:Seminiferous_Tubule"} xref: UMLS:C1519236 {source="ncithesaurus:Seminiferous_Cord"} xref: VHOG:0001363 xref: Wikipedia:Seminiferous_tubule xref: XAO:0003088 is_a: UBERON:0000025 ! tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005904 ! duct of male reproductive system relationship: channel_for CL:0000019 ! sperm relationship: channels_into UBERON:0003959 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! rete testis relationship: contains_process GO:0007283 ! spermatogenesis relationship: develops_from UBERON:0005297 {source="Wikipedia"} ! testis sex cord relationship: part_of UBERON:0000473 ! testis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/49/Seminiferous_tubule_and_sperm_low_mag.jpg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6a/Gray1145.png" xsd:anyURI property_value: UBPROP:0000001 "Any of the coiled tubules located in the testes in which spermatozoa are produced.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010399", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "One of two or three twisted curved tubules in each lobule of the testis in which spermatogenesis occurs. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001363", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/SEMINIFEROUS+TUBULE"} property_value: UBPROP:0000003 "Frogs among amphibians and the amniotes have males with testes that are composed of seminiferous tubules, which differ from ampullae in being long, highly convoluted ductules.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001363", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.688 and Figure 21-28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001350 name: coccyx namespace: uberon def: "A collection of caudal vertebrae in the coccygeal region that are fused and part of the bony pelvis." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "coccygeal skeleton" EXACT [EHDAA2:0000259] synonym: "coccygeal vertebrae I-IV" EXACT [FMA:20229] synonym: "coccyx [coccygeal vertebrae I-IV]" EXACT [FMA:20229] synonym: "coccyx [vertebrae coccygeae I-IV]" EXACT LATIN [FMA:20229, FMA:TA] synonym: "fused caudal vertebrae" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "fused caudal vertebral column" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "os coccygis" EXACT LATIN [FMA:20229, FMA:TA] synonym: "os coccygis" RELATED LATIN [Wikipedia:Coccyx] synonym: "tailbone" RELATED SENSU [FMA:20229] xref: AAO:0000731 xref: EHDAA2:0000259 xref: FMA:20229 xref: GAID:239 xref: galen:Coccyx xref: MESH:D003050 xref: NCIT:C12696 xref: SCTID:182028002 xref: UMLS:C0009194 {source="ncithesaurus:Coccyx"} xref: Wikipedia:Coccyx is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0006076 ! caudal region of vertebral column is_a: UBERON:0008001 {source="FMA"} ! irregular bone intersection_of: UBERON:0006076 ! caudal region of vertebral column intersection_of: derived_from_ancestral_fusion_of UBERON:0001095 ! caudal vertebra intersection_of: part_of UBERON:0001270 ! bony pelvis relationship: anteriorly_connected_to UBERON:0003690 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! fused sacrum relationship: derived_from_ancestral_fusion_of UBERON:0001095 ! caudal vertebra relationship: develops_from UBERON:0007144 ! embryonic post-anal tail relationship: part_of UBERON:0001270 {source="FMA"} ! bony pelvis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/91/Gray100.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Small, bony element consisting of several fused, rudimentary caudal vertebrae; near metamorphosis the hypochord fuses to the coccyx, thereby forming the urostyle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000731", ontology="AAO", source="AAO:Pugener_2002", source="AAO:Pugener_and_Maglia_2008"} property_value: UBPROP:0000007 "coccygeal" xsd:string property_value: UBPROP:0000008 "In humans: The coccyx, commonly referred to as the tailbone, is the final segment of the human vertebral column. Comprising three to five separate or fused vertebrae (the coccygeal vertebrae) below the sacrum, it is attached to the sacrum by a fibrocartilaginous joint, the sacrococcygeal symphysis, which permits limited movement between the sacrum and the coccyx." xsd:string {source="WP,unvetted"} [Term] id: UBERON:0001352 name: external acoustic meatus namespace: uberon def: "A tube running from the outer ear to the middle ear. The human ear canal extends from the pinna to the eardrum and is about 26 mm in length and 7 mm in diameter." [Wikipedia:External_acoustic_meatus] subset: pheno_slim subset: uberon_slim synonym: "auditory canal" EXACT [] synonym: "auditory meatus" RELATED [EHDAA2:0000460] synonym: "ear canal" EXACT [Wikipedia:Ear_canal] synonym: "external acoustic tube" EXACT [FMA:61734] synonym: "external auditory canal" EXACT [] synonym: "external auditory meatus" RELATED [] synonym: "external auditory tube" EXACT [FMA:61734] xref: EHDAA2:0000460 xref: EHDAA:8975 xref: EMAPA:17588 xref: EV:0100356 xref: FMA:61734 xref: GAID:864 xref: galen:ExternalAuditoryMeatus xref: MA:0000260 xref: MESH:D004424 xref: NCIT:C12498 xref: SCTID:181178004 xref: UMLS:C0013444 {source="ncithesaurus:External_Acoustic_Meatus"} xref: VHOG:0000977 xref: Wikipedia:External_acoustic_meatus is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: capable_of_part_of GO:0055127 ! vibrational conductance of sound to the inner ear relationship: develops_from UBERON:0005872 {source="PMID:11237469"} ! 1st arch pharyngeal cleft relationship: part_of UBERON:0001691 {source="FMA"} ! external ear relationship: surrounded_by UBERON:0010065 {source="EHDAA2"} ! auditory meatus epithelium property_value: editor_note "consider revisiting superclass after refinement of CARO/EAO, conduit may not be quite correct." xsd:string property_value: UBPROP:0000011 "tympanic ring, which serves as support for the tympanic membrane, directs invagination of the first pharingeal cleft ectoderm to form the external acoustic meatus (EAM), which provides the outer layer of the membrane[PMID 11237469]" xsd:string property_value: UBPROP:0000012 "subdivision of head in FMA." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001353 name: anal region namespace: uberon def: "The anus and surrounding regions. Encompasses both internal and external regions, where present." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "posterior" RELATED [] synonym: "posterior end of organism" RELATED [] xref: EFO:0000847 xref: EHDAA2:0000122 xref: EHDAA:2931 xref: EMAPA:16831 xref: MA:0000329 xref: MAT:0000042 xref: MIAA:0000042 xref: NCIT:C32069 xref: SCTID:362680001 xref: UMLS:C0230120 {source="ncithesaurus:Anal_Region"} xref: VHOG:0000395 xref: WBbt:0006919 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000475 ! organism subdivision relationship: has_developmental_contribution_from UBERON:0000931 {evidence="cjm"} ! proctodeum relationship: overlaps UBERON:0006866 ! terminal part of digestive tract property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray408.png" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/507" xsd:anyURI property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000395", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001355 name: deep femoral artery namespace: uberon def: "The profunda femoris artery (also known as the deep femoral artery, or the deep artery of the thigh) is a branch of the femoral artery that, as its name suggests, travels more deeply (posteriorly) than the rest of the femoral artery. [WP,unvetted]." [Wikipedia:Deep_femoral_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria profunda femoris" EXACT [] synonym: "profunda femoris artery" EXACT [] xref: EMAPA:37216 {source="MA:th"} xref: FMA:20741 xref: MA:0002027 xref: NCIT:C32436 xref: SCTID:181348000 xref: UMLS:C0226455 {source="ncithesaurus:Deep_Femoral_Artery"} xref: Wikipedia:Deep_femoral_artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: branching_part_of UBERON:0002060 ! femoral artery intersection_of: part_of UBERON:0035551 ! deep vasculature relationship: branching_part_of UBERON:0002060 ! femoral artery relationship: part_of UBERON:0002060 ! femoral artery relationship: part_of UBERON:0035551 ! deep vasculature property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray548.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001356 name: medial circumflex femoral artery namespace: uberon def: "The medial circumflex femoral artery (internal circumflex artery, medial femoral circumflex artery) is an artery in the upper thigh that helps supply blood to the neck of the femur. [WP,unvetted]." [Wikipedia:Medial_circumflex_femoral_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria circumflexa femoris medialis" RELATED LATIN [Wikipedia:Medial_circumflex_femoral_artery] synonym: "medial femoral circumflex artery" EXACT [] xref: EMAPA:37670 {source="MA:th"} xref: FMA:20799 xref: MA:0001996 xref: SCTID:244326008 xref: Wikipedia:Medial_circumflex_femoral_artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0007119 ! neck of femur relationship: branching_part_of UBERON:0001355 {source="FMA"} ! deep femoral artery relationship: part_of UBERON:0001355 ! deep femoral artery relationship: supplies UBERON:0007119 ! neck of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c5/Circumflex_femoral_arteries.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001361 name: femoral vein namespace: uberon def: "In the human body, the femoral vein is a blood vessel that accompanies the femoral artery in the femoral sheath. It begins at the adductor canal (also known as Hunter's canal) and is a continuation of the popliteal vein. It ends at the inferior margin of the inguinal ligament, where it becomes the external iliac vein. [WP,unvetted]." [Wikipedia:Femoral_vein] subset: human_reference_atlas subset: uberon_slim synonym: "vena femoralis" RELATED LATIN [Wikipedia:Femoral_vein] xref: AAO:0010237 xref: EMAPA:17876 xref: FMA:21185 xref: GAID:533 xref: galen:FemoralVein xref: MA:0002118 xref: MESH:D005268 xref: NCIT:C12716 xref: SCTID:362071002 xref: UMLS:C0015809 {source="ncithesaurus:Femoral_Vein"} xref: Wikipedia:Femoral_vein is_a: UBERON:0001638 ! vein is_a: UBERON:0003516 ! hindlimb blood vessel relationship: connected_to UBERON:0001316 ! external iliac vein property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Either of the primary veins in the hindlimbs which collect blood from the hindlimb region.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010237", ontology="AAO", source="AAO:BJB"} [Term] id: UBERON:0001363 name: great saphenous vein namespace: uberon def: "The great saphenous vein (GSV), also greater saphenous vein, is the large (subcutaneous) superficial vein of the leg and thigh. The terms 'safaina' (Greek) and 'el safin' (Arabic) have both been claimed as the origin for the word 'saphenous'. [WP,unvetted]." [Wikipedia:Great_saphenous_vein] subset: human_reference_atlas subset: uberon_slim synonym: "greater saphenous vein" EXACT [] synonym: "large saphenous vein" RELATED [BTO:0003271] synonym: "long saphenous vein" RELATED [] synonym: "vena saphena magna" RELATED LATIN [Wikipedia:Great_saphenous_vein] xref: BTO:0003271 xref: EMAPA:37147 {source="MA:th"} xref: FMA:21376 xref: galen:GreaterSaphenousVein xref: galen:GreatSaphenousVein xref: MA:0002216 xref: NCIT:C33004 xref: SCTID:181402008 xref: UMLS:C0392907 {source="ncithesaurus:Long_Saphenous_Vein"} xref: Wikipedia:Great_saphenous_vein is_a: UBERON:0007318 ! saphenous vein relationship: tributary_of UBERON:0001361 {source="FMA/obol"} ! femoral vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/51/Great_saphenous_vein.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001365 name: sacro-iliac joint namespace: uberon def: "The joint in the bony pelvis between the sacrum and the ilium of the pelvis, which are joined by strong ligaments." [Wikipedia:Sacroiliac_joint] subset: pheno_slim subset: uberon_slim synonym: "articulatio sacro-iliaca" EXACT [] synonym: "sacroiliac joint" EXACT [] xref: EMAPA:19300 xref: FMA:21440 xref: GAID:268 xref: MA:0001506 xref: MESH:D012446 xref: NCIT:C33507 xref: SCTID:182199004 xref: UMLS:C0036036 {source="ncithesaurus:Sacroiliac_Joint"} xref: Wikipedia:Sacroiliac_joint is_a: UBERON:0011107 {source="FMA"} ! synovial joint of pelvic girdle is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001273 ! ilium intersection_of: connects UBERON:0003690 ! fused sacrum relationship: connects UBERON:0001273 ! ilium relationship: connects UBERON:0003690 ! fused sacrum relationship: in_lateral_side_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0001270 ! bony pelvis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray319.png" xsd:anyURI property_value: UBPROP:0000008 "In humans, the sacrum supports the spine and is supported in turn by an ilium on each side" xsd:string [Term] id: UBERON:0001366 name: parietal peritoneum namespace: uberon alt_id: UBERON:0004459 def: "The outer layer of peritoneum that is attached to the abdominal and pelvic walls." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Peritoneum#Types] subset: uberon_slim subset: vertebrate_core synonym: "parietal serous membrane of peritoneum" EXACT [UBERON:cjm] synonym: "peritoneal cavity lining" RELATED [] xref: AAO:0010816 xref: EMAPA:16591 xref: FMA:21451 xref: SCTID:362700006 xref: TAO:0005131 xref: VHOG:0001527 xref: Wikipedia:Parietal_peritoneum xref: ZFA:0005131 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0022351 ! parietal serous membrane intersection_of: UBERON:0022351 ! parietal serous membrane intersection_of: part_of UBERON:0002358 ! peritoneum relationship: attaches_to UBERON:0003697 ! abdominal wall relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002358 ! peritoneum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI property_value: UBPROP:0000001 "Peritoneum attached to the abdominal wall.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010816", ontology="AAO", source="AAO:JMG"} [Term] id: UBERON:0001383 name: muscle of leg namespace: uberon alt_id: UBERON:0003270 def: "A muscle that is part of the region of the hindlimb between the pelvis and ankle." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Leg_muscle] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "leg muscle" EXACT [] synonym: "leg muscle organ" EXACT [OBOL:automatic] synonym: "leg skeletal muscle" EXACT [OBOL:automatic] synonym: "leg skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "muscle of hindlimb zeugopod or stylopod" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "muscle of thigh or crus" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "muscle of upper or lower hindlimb segment" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "muscle of upper/lower leg" EXACT [] synonym: "muscle organ of leg" EXACT [OBOL:automatic] synonym: "skeletal muscle of leg" EXACT [OBOL:automatic] xref: BTO:0000722 xref: EHDAA:8291 xref: EMAPA:19144 xref: EMAPA:19318 xref: MA:0000672 xref: RETIRED_EHDAA2:0000974 xref: Wikipedia:Leg_muscle is_a: UBERON:0003663 ! hindlimb muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0004466 {source="prolog"} ! musculature of leg property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000013 "see notes on UBERON:0000978 for possible confusion over the term 'leg'." xsd:string [Term] id: UBERON:0001394 name: axillary artery namespace: uberon def: "Artery that supplies the axilla." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: uberon_slim synonym: "arteria axillaris" EXACT LATIN [Wikipedia:Axillary_artery] synonym: "axillary part of subclavian artery" EXACT [FMA:22654] synonym: "axillary part of trunk of subclavian artery" EXACT [] xref: EMAPA:18749 xref: FMA:22654 xref: GAID:473 xref: galen:AxillaryArtery xref: MA:0002573 xref: MESH:D001366 xref: NCIT:C32169 xref: SCTID:181321001 xref: UMLS:C0004455 {source="ncithesaurus:Axillary_Artery"} xref: Wikipedia:Axillary_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0009472 ! axilla relationship: connected_to UBERON:0001533 ! subclavian artery relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001467 ! shoulder relationship: supplies UBERON:0009472 ! axilla property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/8/88/Axillary_limits.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In human anatomy, the axillary artery is a large blood vessel that conveys oxygenated blood to the lateral aspect of the thorax, the axilla (armpit) and the upper limb. Its origin is at the lateral margin of the first rib, before which it is called the subclavian artery. After passing the lower margin of teres major it becomes the brachial artery." xsd:string [Term] id: UBERON:0001397 name: subscapular artery namespace: uberon def: "The subscapular artery, the largest branch of the axillary artery, arises at the lower border of the Subscapularis, which it follows to the inferior angle of the scapula, where it anastomoses with the lateral thoracic and intercostal arteries and with the descending branch of the transverse cervical, and ends in the neighboring muscles. About 4 cm. from its origin it gives off two branches, first the scapular circumflex artery and then the thoracodorsal artery. [WP,unvetted]." [Wikipedia:Subscapular_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria subscapularis" RELATED LATIN [Wikipedia:Subscapular_artery] xref: EMAPA:37116 {source="MA:th"} xref: FMA:22677 xref: MA:0002050 xref: NCIT:C33650 xref: SCTID:244311006 xref: UMLS:C0226422 {source="ncithesaurus:Subscapular_Artery"} xref: Wikipedia:Subscapular_artery is_a: UBERON:0001637 ! artery relationship: connected_to UBERON:0001394 ! axillary artery relationship: part_of RO:0002577 ! system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/4c/Axillary_branches.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001415 name: skin of pelvis namespace: uberon def: "A zone of skin that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "pelvic skin" EXACT [] synonym: "pelvis skin" EXACT [] synonym: "pelvis zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37282 {source="MA:th"} xref: FMA:22984 xref: MA:0000546 xref: SCTID:181517009 is_a: UBERON:0003836 ! abdominal segment skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002355 ! pelvic region of trunk [Term] id: UBERON:0001416 name: skin of abdomen namespace: uberon def: "A zone of skin that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] subset: efo_slim subset: pheno_slim synonym: "abdomen skin" EXACT [] synonym: "abdomen zone of skin" EXACT [OBOL:automatic] synonym: "abdominal skin" EXACT [] synonym: "skin of abdomen proper" EXACT [FMA:22988] synonym: "zone of skin of abdomen" EXACT [OBOL:automatic] xref: EFO:0000214 xref: FMA:22988 xref: FMA:23000 xref: MA:0000523 xref: NCIT:C52758 xref: SCTID:361707007 xref: UMLS:C0222166 {source="ncithesaurus:Abdominal_Skin"} is_a: UBERON:0003836 ! abdominal segment skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0001417 name: skin of neck namespace: uberon def: "A zone of skin that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "neck (volume) zone of skin" EXACT [OBOL:automatic] synonym: "neck skin" EXACT [] synonym: "neck zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of neck" EXACT [OBOL:automatic] synonym: "zone of skin of neck (volume)" EXACT [OBOL:automatic] xref: EMAPA:37277 {source="MA:th"} xref: FMA:23021 xref: FMA:23022 xref: MA:0000590 xref: NCIT:C52756 xref: SCTID:361705004 xref: UMLS:C0205030 {source="ncithesaurus:Neck_Skin"} is_a: UBERON:0012180 ! head or neck skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0001418 name: skin of thorax namespace: uberon def: "A zone of skin that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "thoracic skin" EXACT [] synonym: "thorax skin" EXACT [] synonym: "thorax zone of skin" EXACT [OBOL:automatic] synonym: "upper body skin" RELATED [] synonym: "zone of skin of thorax" EXACT [OBOL:automatic] xref: EMAPA:37765 {source="MA:th"} xref: FMA:23028 xref: FMA:23029 xref: MA:0000564 xref: SCTID:281723000 is_a: UBERON:0001085 ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0001419 name: skin of limb namespace: uberon def: "A zone of skin that is part of a limb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "limb skin" EXACT [] synonym: "limb zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of limb" EXACT [OBOL:automatic] xref: EMAPA:32726 xref: FMA:23100 xref: MA:0000694 xref: NCIT:C53276 xref: SCTID:314403009 xref: UMLS:C1282135 {source="ncithesaurus:Skin_of_the_Extremity"} is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002101 ! limb [Term] id: UBERON:0001421 name: pectoral girdle region namespace: uberon def: "An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions." [FMA:23217, https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cingulum membri superioris" EXACT LATIN [FMA:23217, FMA:TA] synonym: "cingulum membri superioris" NARROW [FMA:TA] synonym: "girdle - pectoral" EXACT [] synonym: "pectoral girdle" RELATED [] synonym: "pectoral region" RELATED [] synonym: "shoulder girdle" NARROW [FMA:23217] synonym: "upper limb girdle" NARROW [FMA:23217] xref: EMAPA:37856 {source="MA:th"} xref: FMA:23217 xref: galen:ShoulderGirdle xref: SCTID:229759004 xref: VSAO:0000305 is_a: UBERON:0007823 ! appendage girdle region is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0007823 ! appendage girdle region intersection_of: part_of UBERON:0010708 ! pectoral complex disjoint_from: UBERON:0007831 ! pectoral girdle skeleton relationship: has_skeleton UBERON:0007831 ! pectoral girdle skeleton relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism relationship: part_of UBERON:0010708 ! pectoral complex property_value: IAO:0000232 "this class describes the organism subdivision, NOT the skeleton within. See also: skeleton of pectoral girdle (UBERON:0007831)." xsd:string property_value: RO:0002171 UBERON:0001271 property_value: UBPROP:0000001 "An organism subdivision that includes the pectoral girdle skeleton. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). There is only one instance of the pectoral girdle region per organism.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000305", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"} property_value: UBPROP:0000005 "Note that this class describes the central subdivision of the pectoral girdle complex, NOT the skeleton within.[VSAO]" xsd:string {date_retrieved="2012-09-06", external_class="VSAO:0000305", ontology="VSAO", source="Curator"} [Term] id: UBERON:0001423 name: radius bone namespace: uberon def: "The major preaxial endochondral bone in the anterior zeugopod[Phenoscape]." [PHENOSCAPE:mah] comment: Due to the presence of the radius in Tetrpodomorph fish this element is not inherently linked to the presence of digits or flexor musculature. The corresponding bone in the posterior fin/limb is the tibia.[Phenoscape]. In four-legged animals, the radius is the main load-bearing bone of the lower forelimb. Its structure is similar in most terrestrial tetrapods, but it may be fused with the ulna in some mammals (such as horses) and reduced or modified in animals with flippers or vestigial forelimbs [ISBN:0-03-910284-X] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "radius" EXACT [MA:0001357] xref: AAO:0000788 xref: CALOHA:TS-2199 xref: EMAPA:19103 xref: FMA:23463 xref: GAID:185 xref: galen:Radius xref: MA:0001357 xref: MESH:D011884 xref: NCIT:C12777 xref: SCTID:181940002 xref: UMLS:C0034627 {source="ncithesaurus:Radius_Bone"} xref: VSAO:0005012 xref: Wikipedia:Radius_(bone) is_a: UBERON:0003466 ! forelimb zeugopod bone is_a: UBERON:0003607 ! forelimb long bone is_a: UBERON:0015001 ! radius endochondral element intersection_of: UBERON:0015001 ! radius endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0006286 {evidence="definitional"} ! radius cartilage element relationship: preaxialmost_part_of UBERON:0010703 ! forelimb zeugopod skeleton property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of the two long bones of endochondral origin of the fore-epipodium; it is located on the lateral side of the ulna. Its upper end articulates with both the humerus and the ulna, whereas the lower articulates with the carpals.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000788", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0001424 name: ulna namespace: uberon def: "The major postaxial endochondral bone in the anterior zeugopod[Phenoscape]." [PHENOSCAPE:mah] comment: The corresponding bone in the posterior fin/limb is the fibula. subset: human_reference_atlas subset: pheno_slim subset: uberon_slim xref: AAO:0000789 xref: EMAPA:19104 xref: FMA:23466 xref: GAID:188 xref: galen:Ulna xref: MA:0001358 xref: MESH:D014457 xref: NCIT:C12809 xref: SCTID:181948009 xref: UMLS:C0041600 {source="ncithesaurus:Ulna"} xref: VSAO:0005013 xref: Wikipedia:Ulna is_a: UBERON:0003466 ! forelimb zeugopod bone is_a: UBERON:0003607 ! forelimb long bone is_a: UBERON:0015003 ! ulna endochondral element intersection_of: UBERON:0015003 ! ulna endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0006306 {evidence="definitional"} ! ulna cartilage element relationship: postaxialmost_part_of UBERON:0010703 ! forelimb zeugopod skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/67/Illu_upper_extremity.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of the two long bones of endochondral origin of the fore-epipodium; it is located on the medial (inner) side of the radius. The upper end of the ulna articulates with the lower end of the humerus forming a strong hinge joint with the carpals, whereas the lower articulates with the carpals.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000789", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000007 "ulnar" xsd:string [Term] id: UBERON:0001427 name: radiale namespace: uberon def: "Endochondral proximal carpal bone articulating with the radius." [https://github.com/obophenotype/uberon/issues/112, UBERON:mah] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "navicular bone of hand" EXACT [] synonym: "navicular bone of manus" EXACT [] synonym: "navicular of hand" RELATED [] synonym: "navicular of manus" EXACT [] synonym: "os carpi radiale" EXACT [] synonym: "os naviculare manus" EXACT [Wikipedia:Scaphoid_bone] synonym: "os scaphoideum" EXACT [Wikipedia:Scaphoid_bone] synonym: "radial carpal bone" EXACT [] synonym: "scaphoid" EXACT [MA:0002555, NCBITaxon:40674, Wikipedia:Scaphoid] synonym: "scaphoid bone" EXACT [] synonym: "scaphoideum" EXACT [Wikipedia:Scaphoid_bone] xref: AAO:0000790 xref: EMAPA:37660 {source="MA:th"} xref: FMA:23709 xref: GAID:180 xref: galen:Scaphoid xref: MA:0002555 xref: MESH:D021361 xref: NCIT:C12854 xref: SCTID:181958008 xref: UMLS:C0223724 {source="ncithesaurus:Scaphoid_Bone"} xref: Wikipedia:Scaphoid is_a: UBERON:0001480 ! proximal carpal bone relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/Carpus.png" xsd:anyURI property_value: editor_note "TODO - check AAO placement; in rodents this is fused with the lunate to make the scapholunate" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of two element that constitute the basal row of carpals. It articulates proximally with the radius, mesially with the ulnare (or pars intermedia of the ulnare when the ulnare is fused to the intermedium) and distally with the centrale (also recognized by some authors as element Y). This element originates from one or two condensation centers. Occasionally it may fuse to carpal 5(4), the ulnare, or other elements.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000790", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "the bone of the hand located at the radial side of the carpus and which articulates with the radius, trapezium, trapezoideum, capitate, and lunate bones" xsd:string {source="MP:0010775,MGI:llw2"} property_value: UBPROP:0000013 "In reptiles, birds, and amphibians, this bone is instead commonly referred to as the radiale, because of its articulation with the radius[WP]" xsd:string [Term] id: UBERON:0001428 name: intermedium namespace: uberon def: "Endochondral carpal bone articulating with the ulnare and the radiale." [https://github.com/obophenotype/uberon/issues/113, UBERON:mah] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "intermediate carpal bone" RELATED [] synonym: "intermedium" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "lunar" EXACT [VSAO:0005040] synonym: "lunate" EXACT SENSU [MA:0002556, NCBITaxon:40674] synonym: "lunate bone" EXACT [] synonym: "os carpi intermedium" EXACT [] synonym: "os lunatum" EXACT LATIN [VSAO:0005040] synonym: "os lunatum" RELATED LATIN [Wikipedia:Lunate_bone] synonym: "semilunar" RELATED [] synonym: "semilunar bone" EXACT [] synonym: "semilunate" RELATED [] xref: EMAPA:37659 {source="MA:th"} xref: FMA:23712 xref: GAID:181 xref: galen:Lunate xref: MA:0002556 xref: MESH:D012667 xref: NCIT:C12786 xref: SCTID:181959000 xref: UMLS:C0036624 {source="ncithesaurus:Lunate_Bone"} xref: VSAO:0005040 xref: Wikipedia:Lunate_bone is_a: UBERON:0001480 {source="FMA"} ! proximal carpal bone relationship: connected_to UBERON:0001427 ! radiale relationship: connected_to UBERON:0002445 ! ulnare relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/Carpus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "articulating with the ulnare and the radiale[VSAO]. human articulations: radius proximally capitate and hamate distally scaphoid laterally triangular medially" xsd:string [Term] id: UBERON:0001429 name: pisiform namespace: uberon def: "A laterally positioned sesamoid bone found in close proximity with and occasionally fused to the ulnare." [https://github.com/obophenotype/uberon/issues/116, PHENOSCAPE:ad] subset: human_reference_atlas subset: uberon_slim synonym: "accessory carpal bone" RELATED [MA:0001339] synonym: "os pisiforme" RELATED LATIN [Wikipedia:Pisiform_bone] synonym: "pisiform bone" EXACT [FMA:23718] xref: EMAPA:36165 xref: FMA:23718 xref: galen:Pisiform xref: MA:0001339 xref: NCIT:C12855 xref: SCTID:181966004 xref: SCTID:9181003 xref: UMLS:C0223729 {source="ncithesaurus:Pisiform_Bone"} xref: Wikipedia:Pisiform_bone is_a: UBERON:0001480 {source="FMA", source="MA"} ! proximal carpal bone is_a: UBERON:0007997 ! sesamoid bone of manus relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/Carpus.png" xsd:anyURI property_value: editor_note "check: accessory carpal" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001431 name: distal carpal bone 2 namespace: uberon subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "carpal 2" RELATED [AAO:0000848] synonym: "distal carpal 2" EXACT [VSAO:0005044] synonym: "hand distal carpal bone 2" RELATED [MA:0001341] synonym: "lesser multangular" RELATED [] synonym: "lesser multangular bone" EXACT [FMA:23724] synonym: "lesser multiangular" RELATED [MA:0001341] synonym: "manus distal carpal bone 2" RELATED [] synonym: "os trapezoideum" EXACT [VSAO:0005044] synonym: "trapezoid" EXACT [VSAO:0005044] synonym: "trapezoid bone" EXACT [FMA:23724] xref: AAO:0000848 xref: EMAPA:36174 xref: FMA:23724 xref: galen:Trapezoid xref: MA:0001341 xref: NCIT:C12859 xref: SCTID:361781006 xref: UMLS:C0223741 {source="ncithesaurus:Trapezoid_Bone"} xref: VSAO:0005044 xref: Wikipedia:Trapezoid_bone is_a: UBERON:0001481 ! distal carpal bone is_a: UBERON:0015087 ! distal carpal bone 2 endochondral element intersection_of: UBERON:0015087 ! distal carpal bone 2 endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015088 ! distal carpal bone 2 cartilage property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Small element that articulates with the prepollex, metacarpal II(I) and metacarpal III(II). It may be fused to element Y or carpal 3(2).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000848", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The trapezoid bone (lesser multangular bone) is a carpal bone in tetrapods, including humans. It is the smallest bone in the distal row. It may be known by its wedge-shaped form, the broad end of the wedge constituting the dorsal, the narrow end the palmar surface; and by its having four articular facets touching each other, and separated by sharp edges. It is homologous with the 'second distal carpal' of reptiles and amphibians. The etymology derives from the Greek trapezion which means 'irregular quadrilateral,' from tra- 'four' and peza 'foot' or 'edge. ' Literally, 'a little table' from trapeza meaning 'table' and -oeides 'shaped.[Wikipedia:Trapezoid_bone]" xsd:string {source="Wikipedia:Trapezoid_bone"} property_value: UBPROP:0000008 "located in the distal part of the carpus and articulating with the second metacarpal, the distal carpals 1 and 2 and the radiale.[VSAO] in humans - The capitate articulates with 2nd metacarpal distally, scaphoid proximally, trapezium medially, capitate medially[WP] Amphibians: Small element that articulates with the prepollex, metacarpal II(I) and metacarpal III(II). It may be fused to element Y or carpal 3(2)" xsd:string {source="AAO"} [Term] id: UBERON:0001432 name: distal carpal bone 3 namespace: uberon subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "capitate" EXACT [MA:0001342] synonym: "capitate bone" EXACT [FMA:23727] synonym: "carpal 3" RELATED [AAO:0000849] synonym: "distal carpal 3" EXACT [VSAO:0005045] synonym: "hand distal carpal bone 3" RELATED [MA:0001342] synonym: "magnum" RELATED [VSAO:0005045] synonym: "os capitatum" RELATED [Wikipedia:Capitate_bone] synonym: "os magnum" RELATED [] synonym: "os magnum (carpus)" EXACT [FMA:23727] xref: AAO:0000849 xref: EMAPA:36169 xref: FMA:23727 xref: galen:Capitate xref: MA:0001342 xref: NCIT:C12856 xref: SCTID:181964001 xref: UMLS:C0223733 {source="ncithesaurus:Capitate_Bone"} xref: VSAO:0005045 xref: Wikipedia:Capitate_bone is_a: UBERON:0001481 {source="FMA", source="palaeos"} ! distal carpal bone is_a: UBERON:0015090 ! distal carpal bone 3 endochondral element intersection_of: UBERON:0015090 ! distal carpal bone 3 endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: connected_to UBERON:0001427 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="proximally", source="Wikipedia"} ! radiale relationship: connected_to UBERON:0001428 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="proximally", source="Wikipedia"} ! intermedium relationship: connected_to UBERON:0001431 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="radially", source="Wikipedia"} ! distal carpal bone 2 relationship: connected_to UBERON:0001433 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="ulnar side", source="Wikipedia"} ! distal carpal bone 4 relationship: connected_to UBERON:0003646 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="distally", source="Wikipedia"} ! metacarpal bone of digit 2 relationship: connected_to UBERON:0003647 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="distally", source="Wikipedia"} ! metacarpal bone of digit 3 relationship: connected_to UBERON:0003648 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="distally", source="Wikipedia"} ! metacarpal bone of digit 4 relationship: develops_from UBERON:0015091 ! distal carpal bone 3 cartilage property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/Carpus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Small element that articulates anteriorly with metacarpal III(II). It may be fused to carpals 2(1), 4(3), 5(4), or other elements.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000849", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000008 "medially located and articulates with metacarpals 2-4, distal carpal 5 and the intermedium[VSAO] In the human hand, the capitate bone is the largest of the carpal bones, and occupies the center of the wrist - The capitate articulates with seven bones: the scaphoid and lunate proximally, the second metacarpal, third metacarpal, and fourth metacarpal distally, the lesser multangular on the radial side, and the hamate on the ulnar side" xsd:string {source="WP"} [Term] id: UBERON:0001433 name: distal carpal bone 4 namespace: uberon subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "carpal 4" RELATED [AAO:0000850] synonym: "distal carpal 4" EXACT [VSAO:0005046] synonym: "hamate" EXACT [MA:0001343] synonym: "hamate bone" EXACT [FMA:23730] synonym: "hand distal carpal bone 4" RELATED [MA:0001343] synonym: "os hamatum" RELATED LATIN [VSAO:0005046, Wikipedia:Hamate_bone] synonym: "unciform" RELATED [MA:0001343] synonym: "unciform bone" EXACT [FMA:23730] synonym: "uncinate" RELATED [MA:0001343] xref: AAO:0000850 xref: EMAPA:36172 xref: FMA:23730 xref: galen:Hamate xref: MA:0001343 xref: NCIT:C12860 xref: SCTID:181967008 xref: UMLS:C0560737 {source="ncithesaurus:Hamate_Bone"} xref: VSAO:0005046 xref: Wikipedia:Hamate_bone is_a: UBERON:0001481 {source="FMA"} ! distal carpal bone is_a: UBERON:0015093 ! distal carpal bone 4 endochondral element intersection_of: UBERON:0015093 ! distal carpal bone 4 endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015094 ! distal carpal bone 4 cartilage property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/Carpus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Small element that articulates anteriorly with metacarpal IV(III). It may be fused to carpal 3(2), 5(4), or other elements.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000850", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000008 "articulates with the lunar, distal carpal 3, the ulnare as well as metacarpals 4 and 5.[VSAO]. In the human hand the lunate proximally the fourth and fifth metacarpals distally the triangular medially the capitate laterally[WP] Amphibians: Small element that articulates anteriorly with metacarpal IV(III). It may be fused to carpal 3(2), 5(4), or other elements" xsd:string {source="AAO"} [Term] id: UBERON:0001434 name: skeletal system namespace: uberon def: "Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000027] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "set of all bones and joints" NARROW SENSU [] synonym: "skeleton system" EXACT [] synonym: "Skelettsystem" RELATED [BTO:0001486] xref: AAO:0000566 xref: BTO:0001486 xref: CALOHA:TS-1320 xref: EFO:0000806 xref: EHDAA2:0003168 xref: EMAPA:35773 xref: FMA:23881 xref: MA:0000018 xref: NCIT:C12788 xref: TAO:0000434 xref: UMLS:C0037253 {source="ncithesaurus:Skeletal_System"} xref: VHOG:0001254 xref: VSAO:0000027 xref: XAO:0003060 xref: ZFA:0000434 is_a: UBERON:0011216 ! organ system subdivision intersection_of: UBERON:0011216 ! organ system subdivision intersection_of: has_part UBERON:0004288 ! skeleton intersection_of: has_part UBERON:0004770 ! articular system disjoint_from: UBERON:0001474 ! bone element disjoint_from: UBERON:0002204 ! musculoskeletal system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0004288 ! skeleton relationship: has_part UBERON:0004770 ! articular system relationship: part_of UBERON:0002204 ! musculoskeletal system property_value: RO:0002171 UBERON:0001016 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/The-skeletal-system" xsd:anyURI property_value: UBPROP:0000001 "Anatomical system consisting of multiple elements and tissues that provides physical support.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000434", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000027", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} property_value: UBPROP:0000001 "System that provides physical support to the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000566", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "By taking a holistic approach, integration of the evidence from molecular and developmental features of model organisms, the phylogenetic distribution in the 'new animal phylogeny' and the earliest fossilized remains of mineralized animal skeletons suggests independent origins of the skeleton at the phylum level.[debated][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001254", ontology="VHOG", source="DOI:10.1159/000324245 Donoghue PCJ, Sansom IJ, Origin and early evolution of vertebrate skeletonization. Microscopy research and technique (2002)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "skeletal" xsd:string property_value: UBPROP:0000012 "GO defines skeletal system very generically: The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton) GO:0001501; however, all annotations are to vertebrates" xsd:string {external_ontology="GO"} [Term] id: UBERON:0001435 name: carpal bone namespace: uberon def: "A bone that is part of the carpal skeleton. Examples: scaphoid, lunate, capitate[cjm]." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "bone of carpus" EXACT [] synonym: "carpal" EXACT [PHENOSCAPE:ad] synonym: "carpal skeleton bone" EXACT [] synonym: "carpus bone" RELATED [EMAPA:25056] xref: EMAPA:25056 xref: FMA:23889 xref: GAID:179 xref: galen:CarpalBone xref: MA:0000296 xref: MESH:D002348 xref: NCIT:C12688 xref: SCTID:83936004 xref: UMLS:C0007285 {source="ncithesaurus:Carpal_Bone"} xref: Wikipedia:Carpus is_a: UBERON:0003656 ! mesopodium bone is_a: UBERON:0005897 ! manus bone is_a: UBERON:0015049 ! carpus endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0004452 ! carpal region disjoint_from: UBERON:0012358 ! manual digitopodium bone relationship: develops_from UBERON:0006213 ! carpus cartilage element property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/58/Carpus.svg" xsd:anyURI property_value: UBPROP:0000008 "In tetrapods, the carpals is the sole cluster of the bones in the wrist between the radius and ulna and the metacarpus. The bones of the carpus do not belong to individual fingers (or toes in quadrupeds), whereas those of the metacarpus do. The corresponding part of the foot is the tarsus. The carpal bones allow the wrist to move and rotate vertically, horizontally and laterally. In human anatomy, the main role of the carpus is to facilitate effective positioning of the hand and powerful use of the extensors and flexors of the forearm, but the mobility of individual carpal bones increase the freedom of movements at the wrist." xsd:string {source="Wikipedia:Carpus"} [Term] id: UBERON:0001436 name: phalanx of manus namespace: uberon def: "A phalanx that is part of a forelimb autopod[Automatically generated definition]." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Phalanges_of_the_hand] subset: pheno_slim synonym: "bone of finger" RELATED [FMA:23914] synonym: "digital bone of manus" NARROW [OBOL:automatic] synonym: "digitus manus phalanx" EXACT [OBOL:automatic] synonym: "finger phalanx" EXACT [OBOL:automatic] synonym: "hand digit phalanx" EXACT [OBOL:automatic] synonym: "hand phalanx" EXACT [MA:0000306] synonym: "manual phalanx" EXACT [] synonym: "phalanges of fore digit" RELATED PLURAL [AAO:0000947] synonym: "phalanx of digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of digitus manus" EXACT [OBOL:automatic] synonym: "phalanx of finger" EXACT [FMA:23914] synonym: "phalanx of fore digit" EXACT [] synonym: "phalanx of hand" EXACT [] synonym: "phalanx of hand digit" EXACT [OBOL:automatic] synonym: "phalanx of manual digit" EXACT [] xref: AAO:0000947 xref: EMAPA:32650 xref: FMA:23914 xref: http://mbe.oxfordjournals.org/content/26/3/613/F1.large.jpg xref: MA:0000306 xref: NCIT:C52771 xref: SCTID:181976001 xref: SCTID:361100001 xref: UMLS:C0223792 {source="ncithesaurus:Hand_Phalanx"} xref: Wikipedia:Phalanges_of_the_hand is_a: UBERON:0003221 ! phalanx is_a: UBERON:0003607 ! forelimb long bone is_a: UBERON:0004249 ! manual digit bone is_a: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: develops_from UBERON:0010686 ! manual digit phalanx cartilage element property_value: UBPROP:0000001 "Dumb-bell shaped bones of endochondral origin with cartilaginous epiphyses that make the four digits of the manus. The terminal phalanges are much smaller than the proximal and penultimate phalanges. The typical phalangeal formula of the manus, in a medial to lateral sequence, is 2-2-3-3.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000947", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0001437 name: epiphysis namespace: uberon def: "The head of a long bone that articulates with a neighboring skeletal element and is separated from the shaft by the epiphyseal plate until bone growth stops. At that time, the plate disappears and the head and shaft are united[MESH,modified]." [http://orcid.org/0000-0002-6601-2165, MESH:A02.835.232.251] subset: pheno_slim subset: uberon_slim synonym: "bone epiphysis" EXACT [] synonym: "end of long bone" EXACT [] synonym: "epiphyses" EXACT PLURAL [] synonym: "long bone epiphysis" EXACT [] xref: AAO:0000742 xref: BTO:0000413 xref: EMAPA:35508 xref: FMA:24012 xref: MA:0001362 xref: MESH:D004838 xref: NCIT:C32529 xref: NCIT:C52722 xref: SCTID:244701002 xref: UMLS:C1708734 {source="ncithesaurus:Long_Bone_Epiphysis"} xref: Wikipedia:Epiphysis is_a: UBERON:0005055 ! zone of long bone relationship: contributes_to_morphology_of UBERON:0002495 ! long bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/94/Illu_long_bone.jpg" xsd:anyURI property_value: seeAlso UBERON:0006776 property_value: UBPROP:0000001 "Cartilaginous expansion at the distal end of an anterior rib or transverse process that serves for the attachment of muscles suspending the pectoral girdle to the vertebral column.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000742", ontology="AAO", source="AAO:Pugener_2002"} property_value: UBPROP:0000001 "Subdivision of long bone which forms its expanded proximal or distal articular end; together with other the subdivisions of long bone, it constitutes the long bone. Examples: proximal epiphysis of humerus, distal epiphysis of femur." xsd:string {source="FMA:24012"} property_value: UBPROP:0000007 "epiphyseal" xsd:string property_value: UBPROP:0000007 "epiphysial" xsd:string [Term] id: UBERON:0001438 name: metaphysis namespace: uberon def: "Zone of long bone that is between the epiphysis and diaphysis. Subdivision of diaphysis which forms the proximal or distal end of diaphysis next to the epiphysis; together with diaphysis proper, it constitutes the diaphysis. Examples: proximal metaphysis of humerus, distal metaphysis of femur.[FMA]." [FMA:24014, Wikipedia:Metaphysis] subset: pheno_slim subset: uberon_slim synonym: "diaphyseal end of long bone" EXACT [] synonym: "long bone metaphysis" EXACT [] synonym: "metaphyses" EXACT PLURAL [] xref: EMAPA:35509 xref: FMA:24014 xref: MA:0001363 xref: NCIT:C52723 xref: SCTID:304581004 xref: UMLS:C0222671 {source="ncithesaurus:Metaphysis"} xref: Wikipedia:Metaphysis is_a: UBERON:0005055 ! zone of long bone relationship: adjacent_to UBERON:0006861 ! diaphysis proper relationship: contributes_to_morphology_of UBERON:0002495 ! long bone relationship: part_of UBERON:0004769 ! diaphysis property_value: editor_note "todo - decide - adjacent to or containing epiphyseal plate? AO Notes: FMA the metaphysis is part of the diaphysis, but not in MA." xsd:string property_value: UBPROP:0000001 "Subdivision of diaphysis which forms the proximal or distal end of diaphysis next to the epiphysis; together with diaphysis proper, it constitutes the diaphysis. Examples: proximal metaphysis of humerus, distal metaphysis of femur.[FMA]" xsd:string {source="FMA:24014"} [Term] id: UBERON:0001440 name: forelimb skeleton namespace: uberon def: "The collection of all skeletal elements in a free forelimb region. Excludes the pectoral girdle." [https://orcid.org/0000-0002-6601-2165] synonym: "bones of upper limb" EXACT [] synonym: "fore limb skeleton" EXACT [] synonym: "forelimb skeleton" EXACT [VHOG:0001256] synonym: "free upper limb skeleton" EXACT [FMA:24142] synonym: "ossa membri superioris" EXACT LATIN [FMA:24139, FMA:TA] synonym: "pectoral limb skeleton" EXACT [] synonym: "set of bones of upper limb" EXACT [] synonym: "skeleton of forelimb" EXACT [] synonym: "skeleton of free upper limb" EXACT [FMA:24142] synonym: "skeleton of pectoral limb" EXACT [] synonym: "skeleton of upper limb" EXACT [FMA:24139] synonym: "upper limb skeleton" EXACT [EHDAA2:0002222] synonym: "wing skeleton" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: AAO:0000202 xref: EHDAA2:0002222 xref: EMAPA:32623 xref: FMA:24142 xref: VHOG:0001256 xref: VSAO:0000151 xref: XAO:0003061 is_a: UBERON:0004381 ! skeleton of limb is_a: UBERON:0007272 ! pectoral appendage skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 {source="FMA"} ! forelimb relationship: part_of UBERON:0012475 ! skeleton of pectoral complex relationship: proximally_connected_to UBERON:0007831 ! pectoral girdle skeleton relationship: skeleton_of UBERON:0002102 ! forelimb property_value: editor_note "TODO - find a home for: FMA:24139 ! skeleton of upper limb" xsd:string property_value: RO:0002475 UBERON:0001441 property_value: UBPROP:0000001 "Skeletal structure of the paired, anterior appendages.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000202", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000202", ontology="AAO"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001256", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001441 name: hindlimb skeleton namespace: uberon def: "Subdivision of skeleton consisting of all skeletal elements in an hindlimb region." [https://orcid.org/0000-0002-6601-2165] comment: TOOD - find a home for: FMA:24140 subset: uberon_slim synonym: "bones of lower limb" EXACT [] synonym: "free lower limb skeleton" EXACT [FMA:24144] synonym: "hind limb skeleton" EXACT [XAO:0003062] synonym: "hind-limb skeleton" EXACT [VSAO:0000152] synonym: "hindlimb skeleton" EXACT [VHOG:0001255] synonym: "lower limb skeleton" EXACT [] synonym: "ossa membri inferioris" EXACT LATIN [FMA:24140, FMA:TA] synonym: "set of bones of lower limb" EXACT [] synonym: "skeleton of free lower limb" EXACT [FMA:24144] synonym: "skeleton of lower limb" EXACT [FMA:24140] xref: AAO:0000217 xref: EHDAA2:0002226 xref: EMAPA:32633 xref: FMA:24144 xref: VHOG:0001255 xref: VSAO:0000152 xref: XAO:0003062 is_a: UBERON:0004381 ! skeleton of limb is_a: UBERON:0007273 ! pelvic appendage skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 {source="FMA"} ! hindlimb relationship: part_of UBERON:0012476 ! skeleton of pelvic complex relationship: proximally_connected_to UBERON:0007832 ! pelvic girdle skeleton relationship: skeleton_of UBERON:0002103 ! hindlimb property_value: UBPROP:0000001 "Skeletal structure of the paired, posterior appendages.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000217", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000217", ontology="AAO"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001255", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001442 name: skeleton of manus namespace: uberon def: "Subdivision of skeleton that is the collection of all skeletal elements in a manus, which is the distal section of the anterior forelimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the wrist, palm, and fingers)[Phenoscape]." [https://github.com/obophenotype/uberon/issues/74, https://orcid.org/0000-0002-6601-2165, PHENOSCAPE:MAH] comment: here 'manus' includes both the wrist region, metatarsal region and acropodial region subset: pheno_slim synonym: "anterior autopodium" RELATED [VSAO:0005020, VSAO:NI] synonym: "anterior autopodium skeleton" EXACT [] synonym: "bones of hand" EXACT [FMA:24159] synonym: "fore autopod skeleton" EXACT [] synonym: "forelimb autopod skeleton" EXACT [] synonym: "hand region skeleton" EXACT [EHDAA2:0002227] synonym: "hand skeleton" EXACT [FMA:24159] synonym: "manual skeleton" EXACT [] synonym: "manus" RELATED [VSAO:0005020, VSAO:NI] synonym: "manus skeleton" EXACT [] synonym: "ossa manus" EXACT LATIN [FMA:24159, FMA:TA] synonym: "set of bones of hand" EXACT [FMA:24159] synonym: "skeleton of hand" EXACT [FMA:24159] xref: EHDAA2:0002227 xref: EMAPA:32643 xref: FMA:24159 xref: VSAO:0005020 is_a: UBERON:0006717 ! autopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002398 ! manus disjoint_from: UBERON:0001445 {source="lexical"} ! skeleton of pes relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0001440 {source="EHDAA2"} ! forelimb skeleton relationship: part_of UBERON:0002398 ! manus relationship: skeleton_of UBERON:0002398 ! manus property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0001444 name: subdivision of head namespace: uberon subset: non_informative synonym: "head region" RELATED [] synonym: "head subdivision" EXACT [] synonym: "region of head" RELATED [] xref: FMA:24218 xref: SCTID:123852005 xref: XAO:0000040 is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0001445 name: skeleton of pes namespace: uberon def: "Subdivision of skeleton that is the collection of all skeletal elements in a pes, which is the distal section of the posterior hindlimb skeleton consisting of the mesopodium, the metapodium and the acropodium (e.g. including the ankle, sole, and toes)[Phenoscape]." [https://github.com/obophenotype/uberon/issues/75, https://orcid.org/0000-0002-6601-2165, PHENOSCAPE:MAH] comment: here 'pes' includes both the ankle region, metatarsals and acropodial region subset: pheno_slim synonym: "foot region skeleton" EXACT [EHDAA2:0002228] synonym: "foot skeleton" EXACT [FMA:24222] synonym: "pedal skeleton" EXACT [] synonym: "pes" RELATED INCONSISTENT [VSAO:0005021, VSAO:NI] synonym: "pes skeleton" EXACT [] synonym: "posterior autopodium" RELATED [VSAO:0005021, VSAO:NI] synonym: "posterior autopodium skeleton" EXACT [] synonym: "set of bones of foot" EXACT [FMA:24222] synonym: "skeleton of foot" EXACT [FMA:24222] xref: EHDAA2:0002228 xref: FMA:24222 xref: VSAO:0005021 is_a: UBERON:0006717 ! autopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002387 ! pes relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0001441 {source="EHDAA2"} ! hindlimb skeleton relationship: part_of UBERON:0002387 ! pes relationship: skeleton_of UBERON:0002387 ! pes property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0001446 name: fibula namespace: uberon def: "The major postaxial endochondral bone in the posterior zeugopod[Phenoscape]." [PHENOSCAPE:mah] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim xref: AAO:0000891 xref: BTO:0002346 xref: CALOHA:TS-2203 xref: EFO:0003052 xref: EMAPA:19141 xref: FMA:24479 xref: GAID:202 xref: galen:Fibula xref: MA:0001360 xref: MESH:D005360 xref: NCIT:C12718 xref: SCTID:302529003 xref: UMLS:C0016068 {source="ncithesaurus:Fibula"} xref: Wikipedia:Fibula is_a: UBERON:0003608 ! hindlimb long bone is_a: UBERON:0004251 ! hindlimb zeugopod bone is_a: UBERON:0015013 ! fibula endochondral element intersection_of: UBERON:0015013 ! fibula endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010851 ! fibula cartilage element relationship: postaxialmost_part_of UBERON:0010720 ! hindlimb zeugopod skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/16/Illu_lower_extremity.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of the two long bones of endochondral origin of the hind-epipodium; it is a rather more slender bone than the tibia but of about the same length.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000891", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000007 "fibular" xsd:string [Term] id: UBERON:0001447 name: tarsal bone namespace: uberon def: "A bone that is part of the tarsal skeleton. Examples: calcaneus, talus, centralia." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "ankle bone" EXACT [FMA:24491] synonym: "bone of ankle" EXACT [FMA:24491] synonym: "bone of tarsal skeleton" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "bone of tarsus" EXACT [FMA:24491] synonym: "bony tarsus" RELATED [BTO:0002343] synonym: "hind mesopodium" RELATED [AAO:0000220] synonym: "ossa tarsalia" EXACT PLURAL [FMA:71339, FMA:TA] synonym: "ossa tarsi" EXACT PLURAL [FMA:71339, FMA:TA] synonym: "tarsal" RELATED [BTO:0002343] synonym: "tarsus osseus" RELATED [BTO:0002343] xref: BTO:0002343 xref: EMAPA:25072 xref: FMA:24491 xref: GAID:194 xref: galen:TarsalBone xref: MA:0000297 xref: MESH:D013639 xref: NCIT:C12796 xref: SCTID:108372004 xref: UMLS:C0039316 {source="ncithesaurus:Tarsal_Bone"} is_a: UBERON:0003656 ! mesopodium bone is_a: UBERON:0005899 ! pes bone is_a: UBERON:0015050 ! tarsus endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0004454 ! tarsal region disjoint_from: UBERON:0012359 ! pedal digitopodium bone relationship: develops_from UBERON:0010541 ! tarsus cartilage element property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/b/bf/Ankle_en.svg" xsd:anyURI property_value: UBPROP:0000008 "In primitive tetrapods, such as Trematops, the tarsus consists of three rows of bones. There are three proximal tarsals, the tibiale, intermedium, and fibulare, named for their points of articulation with the bones of the lower limb. These are followed by a second row of four bones, referred to as the centralia (singular: centrale), and then a row of five distal tarsals, each articulating with a single metatarsal. In the great majority of tetrapods, including all of those alive today, this simple pattern is modified by the loss and fusion of various of the bones.[3] In reptiles and mammals, there are normally just two proximal tarsals, the calcaneus (equivalent to the amphibian fibulare) and the talus (probably derived from a fusion of multiple bones). In mammals, including humans, the talus forms a hinge joint with the tibia, a feature especially well developed in the artiodactyls. The calcaneus is also modified, forming a heel for the attachment of the Achilles tendon. Neither of these adaptations is found in reptiles, which have a relatively simple structure to both bones.[3] The fifth distal tarsal disappears relatively early in evolution, with the remainder becoming the cuneiform and cuboid bones. Reptiles usually retain two centralia, while mammals typically have only one (the navicular).[3] In birds, the tarsus has disappeared, with the proximal tarsals having fused with the tibia, the centralia having disappeared, and the distal bones having fused with the metatarsals to form a single tarsometatarsus bone, effectively giving the leg a third segment" xsd:string {source="Wikipedia:Tarsus_(skeleton)"} [Term] id: UBERON:0001448 name: metatarsal bone namespace: uberon def: "The metatarsus or metatarsal bones are a group of five long bones in the pes located between the tarsal bones of the hind- and mid-pes and the phalanges of the toes. Lacking individual names, the metatarsal bones are numbered from the medial side (side of big toe): the first, second, third, fourth, and fifth metatarsal. The metatarsals are analogous to the metacarpal bones of the manus. [WP,unvetted]." [Wikipedia:Metatarsal_bone] subset: pheno_slim subset: uberon_slim synonym: "metatarsal" EXACT [] synonym: "ossa metatarsalia" RELATED PLURAL [BTO:0002347] synonym: "ossa metatarsi" RELATED [BTO:0002347] xref: BTO:0002347 xref: EMAPA:32940 xref: EMAPA:36159 xref: FMA:24492 xref: GAID:193 xref: galen:Metatarsal xref: MA:0000303 xref: MESH:D008682 xref: NCIT:C12752 xref: SCTID:302532000 xref: UMLS:C0025584 {source="ncithesaurus:Metatarsal_Bone"} xref: Wikipedia:Metatarsal_bone is_a: UBERON:0003608 ! hindlimb long bone is_a: UBERON:0003821 {is_inferred="true"} ! metapodium bone is_a: UBERON:0012359 ! pedal digitopodium bone is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000983 ! metatarsus region relationship: connected_to UBERON:0001447 ! tarsal bone relationship: connected_to UBERON:0001449 ! phalanx of pes relationship: part_of UBERON:0010545 ! metatarsus skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/52/Gray291.png" xsd:anyURI [Term] id: UBERON:0001449 name: phalanx of pes namespace: uberon alt_id: UBERON:0004272 def: "A phalanx that is part of a hindlimb autopod[Automatically generated definition]." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Phalanges_of_the_foot] subset: pheno_slim synonym: "bone of toe" RELATED [FMA:24493] synonym: "digital bone of pes" BROAD [OBOL:automatic] synonym: "digitus pedis phalanx" EXACT [OBOL:automatic] synonym: "foot digit phalanx" EXACT [OBOL:automatic] synonym: "foot phalanx" EXACT [MA:0000305] synonym: "pedal phalanx" EXACT [] synonym: "phalanges of hind digit" RELATED PLURAL [AAO:0000930] synonym: "phalanx of digit of foot" EXACT [OBOL:automatic] synonym: "phalanx of digitus pedis" EXACT [OBOL:automatic] synonym: "phalanx of foot digit" EXACT [OBOL:automatic] synonym: "phalanx of hind digit" EXACT [] synonym: "phalanx of pes" EXACT [] synonym: "phalanx of toe" EXACT [FMA:24493] synonym: "toe phalanx" EXACT [OBOL:automatic] xref: AAO:0000930 xref: EMAPA:32941 xref: FMA:24493 xref: MA:0000305 xref: NCIT:C52772 xref: ncithesaurus:Phalanx_of_the_Foot xref: SCTID:302533005 xref: UMLS:C0584876 {source="ncithesaurus:Foot_Phalanx"} xref: Wikipedia:Phalanges_of_the_foot is_a: UBERON:0003221 ! phalanx is_a: UBERON:0003608 ! hindlimb long bone is_a: UBERON:0004248 ! pedal digit bone is_a: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0002387 ! pes relationship: develops_from UBERON:0010685 ! pedal digit phalanx cartilage element property_value: UBPROP:0000001 "Dumb-bell shaped bones of endochondral origin with cartilaginous epiphyses that make the five digits of the pes. The terminal phalanges are much smaller than the proximal and penultimate phalanges. The typical phalangeal formula of the pes, in a medial to lateral sequence, is 2(1)-2-3-4(3)-3(2).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000930", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0001450 name: calcaneus namespace: uberon def: "The postaxial bone of the proximal tarsals series[Phenoscape]." [https://github.com/obophenotype/uberon/issues/72, PHENOSCAPE:mah] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "calcaneal bone" EXACT [BTO:0002355] synonym: "calcanei" RELATED PLURAL [] synonym: "calcaneum" EXACT [MA:0001348] synonym: "calcaneus bone" EXACT [UBERON:cjm] synonym: "fibulare" RELATED [AAO:0000913, ISBN:0073040584, VSAO:0005016, Wikipedia:Calcaneus] synonym: "heel bone" RELATED [BTO:0002355] synonym: "os calcis" EXACT LATIN [FMA:24496] synonym: "os tarsi fibulare" RELATED [BTO:0002355] xref: BTO:0002355 xref: EMAPA:19134 xref: FMA:24496 xref: galen:Calcaneum xref: MA:0001348 xref: MESH:D002111 xref: NCIT:C32250 xref: SCTID:182099002 xref: UMLS:C0006655 {source="ncithesaurus:Calcaneum"} xref: VSAO:0005016 xref: Wikipedia:Calcaneus is_a: UBERON:0011679 ! proximal tarsal bone is_a: UBERON:0015014 ! calcaneum endochondral element intersection_of: UBERON:0015014 ! calcaneum endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010842 ! calcaneum cartilage element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: postaxialmost_part_of UBERON:0009879 ! tarsal skeleton property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/a/a9/Subtalar_Joint.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "calcaneal" xsd:string property_value: UBPROP:0000008 "synonymous with the fibulare of basal tetrapods." xsd:string [Term] id: UBERON:0001451 name: navicular bone of pes namespace: uberon def: "The oval-shaped tarsal bone found between the talus and the 3 cuneiform bones." [MGI:llw2, MP:0009727] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "central tarsal bone" RELATED [] synonym: "centrale" BROAD [] synonym: "centrale (hind)" EXACT [AAO:0000924] synonym: "navicular" EXACT [] synonym: "navicular bone of foot" EXACT [FMA:24499] synonym: "navicular of foot" EXACT [FMA:24499] synonym: "navicular of pes" EXACT [] synonym: "os naviculare" EXACT LATIN [FMA:24499, FMA:TA] synonym: "os naviculare" RELATED LATIN [Wikipedia:Navicular_bone] synonym: "os naviculare pedis" EXACT [BTO:0002356] synonym: "os tarsi centrale" EXACT LATIN [NominaAnatomicaVeterinaria:2005] xref: AAO:0000924 xref: BTO:0002356 xref: EMAPA:36180 xref: FMA:24499 xref: galen:Navicular xref: MA:0001349 xref: NCIT:C33162 xref: SCTID:182100005 xref: UMLS:C0223947 {source="ncithesaurus:Navicular_Bone"} xref: Wikipedia:Navicular_bone is_a: UBERON:0001447 ! tarsal bone is_a: UBERON:0012131 ! centrale relationship: distally_connected_to UBERON:0010721 {notes="numbers vary"} ! distal tarsal bone relationship: proximally_connected_to UBERON:0002395 ! talus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray276.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Oval tarsal element that is located on the center of the mesopodium. It articulates with all other elements of the tarsus except tarsal 5.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000924", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000008 "connections vary depending on species. AAO: Oval tarsal element that is located on the center of the mesopodium. It articulates with all other elements of the tarsus except tarsal 5. In humans: there is a cuboid instead of distal tarsal 4 and 5 - may articulate laterally with the cuboid" xsd:string {source="WP"} [Term] id: UBERON:0001456 name: face namespace: uberon def: "A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc)." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "facia/facies" RELATED LATIN [Wikipedia:Face] synonym: "visage" RELATED [BTO:0003369] xref: BTO:0003369 xref: CALOHA:TS-2216 xref: EMAPA:32763 xref: FMA:24728 xref: GAID:64 xref: galen:Face xref: HAO:0000316 xref: MA:0002473 xref: MESH:D005145 xref: NCIT:C13071 xref: SCTID:302549007 xref: UMLS:C0015450 {source="ncithesaurus:Face"} xref: Wikipedia:Face is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001444 ! subdivision of head relationship: contributes_to_morphology_of UBERON:0000033 ! head relationship: has_part UBERON:0000018 {gci_filler="NCBITaxon:50557", gci_relation="part_of"} ! compound eye relationship: has_part UBERON:0000165 ! mouth relationship: has_part UBERON:0011156 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! facial skeleton relationship: has_skeleton UBERON:0011156 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! facial skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/55/Mona_Lisa_headcrop.jpg" xsd:anyURI property_value: UBPROP:0000001 "Subdivision of head which consists of the viscerocranium and all layers superficial to it. Examples: There is only one face." xsd:string {source="FMA:24728"} property_value: UBPROP:0000001 "The area that extends from the median ocellus to the oral foramen[HAO]." xsd:string {source="HAO:0000316", source="http://api.hymao.org/api/ref/67791", taxon="NCBITaxon:7399"} property_value: UBPROP:0000007 "facial" xsd:string property_value: UBPROP:0000011 "The face develops from outward growth of tissue located rostral to the cranium & pharynx. The lower jaw and most of the upper jaw are formed by growth of the first pharyngeal (branchial) arch. The upper incisor region and the nose and forehead (frontal region) are formed from tissue located rostral to the neural tube (frontonasal prominence)" xsd:string {source="vanat.cvm.umn.edu/TFFlectPDFs/LectFaceDevelop.pdf"} [Term] id: UBERON:0001458 name: skin of lip namespace: uberon def: "A zone of skin that is part of a lip [Automatically generated definition]." [OBOL:automatic] synonym: "lip skin" EXACT [] synonym: "lip zone of skin" EXACT [OBOL:automatic] synonym: "skin of lips" RELATED PLURAL [] synonym: "zone of skin of lip" EXACT [OBOL:automatic] xref: EMAPA:37643 {source="MA:th"} xref: FMA:24764 xref: MA:0001579 xref: NCIT:C12291 xref: SCTID:244092005 xref: UMLS:C0222101 {source="ncithesaurus:Skin_of_the_Lip"} is_a: UBERON:0001084 ! skin of head intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001833 ! lip relationship: part_of UBERON:0001833 ! lip [Term] id: UBERON:0001459 name: skin of external ear namespace: uberon def: "A zone of skin that is part of a external ear [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "auricular region of head zone of skin" EXACT [OBOL:automatic] synonym: "auricular region zone of skin" EXACT [OBOL:automatic] synonym: "ear skin" EXACT [] synonym: "external ear skin" EXACT [] synonym: "external ear zone of skin" EXACT [OBOL:automatic] synonym: "outer ear zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of auricular region" EXACT [OBOL:automatic] synonym: "zone of skin of auricular region of head" EXACT [OBOL:automatic] synonym: "zone of skin of external ear" EXACT [OBOL:automatic] synonym: "zone of skin of outer ear" EXACT [OBOL:automatic] xref: EMAPA:35301 xref: FMA:24775 xref: MA:0001233 xref: NCIT:C49481 xref: SCTID:244073008 xref: UMLS:C0222110 {source="ncithesaurus:Ear_Skin"} is_a: UBERON:0001084 ! skin of head intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001691 ! external ear relationship: part_of UBERON:0001757 ! pinna [Term] id: UBERON:0001460 name: arm namespace: uberon def: "The part of the forelimb extending from the shoulder to the autopod[cjm]." [Wikipedia:Arm] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "brachium" RELATED LATIN [Wikipedia:Arm] synonym: "upper extremity" RELATED [MESH:A01.378.800] xref: BTO:0001435 xref: CALOHA:TS-2204 xref: EFO:0001410 xref: EHDAA2:0000140 xref: EHDAA:4164 xref: EHDAA:6210 xref: EHDAA:8275 xref: EMAPA:17413 xref: GAID:52 xref: MA:0000033 xref: MESH:D001132 xref: VHOG:0000339 xref: Wikipedia:Arm is_a: UBERON:0006058 ! multi-limb segment region is_a: UBERON:0008785 ! upper limb segment relationship: distally_connected_to UBERON:0002398 ! manus relationship: proximally_connected_to UBERON:0001467 ! shoulder property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Upperarm.jpg" xsd:anyURI property_value: editor_note "currently declared as overlapping hand, as AOs disagree over whether some wrist parts are in the arm or hand" xsd:string property_value: IAO:0000232 "this class refers to the combination of the stylopod and zeugopod of a forelimb. Sometimes (cf FMA), 'arm' denotes the stylopod only; sometimes (cf MA), 'arm' denotes the part of the forelimb covering both (i.e. shoulder to hand). Also note distinction between arm and forelimb: hand is part of forelimb, but not part of arm" xsd:string property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000339", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001461 name: elbow namespace: uberon def: "The elbow is the region surrounding the elbow-joint-the ginglymus or hinge joint in the middle of the arm. Three bones form the elbow joint: the humerus of the upper arm, and the paired radius and ulna of the forearm. The bony prominence at the very tip of the elbow is the olecranon process of the ulna, and the inner aspect of the elbow is called the antecubital fossa. [WP,unvetted,human-specific]." [Wikipedia:Elbow] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "articulatio cubiti" RELATED LATIN [Wikipedia:Elbow] synonym: "cubital region" EXACT [] synonym: "elbow limb segment" EXACT [] synonym: "elbow region" EXACT [] xref: CALOHA:TS-2222 xref: EFO:0003069 xref: EHDAA2:0000429 xref: EHDAA:4166 xref: EHDAA:6212 xref: EMAPA:17414 xref: FMA:24901 xref: GAID:54 xref: galen:Elbow xref: MA:0000036 xref: MESH:D004550 xref: SCTID:76248009 xref: VHOG:0000340 xref: Wikipedia:Elbow is_a: UBERON:0008785 ! upper limb segment relationship: part_of UBERON:0001460 {source="EHDAA2"} ! arm property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/5c/Elbow_coude.JPG" xsd:anyURI property_value: UBPROP:0000007 "cubital" xsd:string property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group" xsd:string [Term] id: UBERON:0001463 name: manual digit 1 namespace: uberon def: "1st (preaxial) digit of the manus[Wikipedia]." [PMCID:PMC2553264, Wikipedia:Thumb] subset: pheno_slim subset: uberon_slim synonym: "alula" NARROW SENSU [Wikipedia:Alula] synonym: "digit 1 of fore-paw" EXACT [EMAPA:17429] synonym: "digit 1 of manus" EXACT [] synonym: "digitus 1" BROAD [] synonym: "digitus I" BROAD LATIN [Wikipedia:Thumb] synonym: "digitus primus" BROAD LATIN [Wikipedia:Thumb] synonym: "digitus primus [I]" BROAD [] synonym: "finger 1" EXACT [EHDAA2:0000511] synonym: "first digit of hand" EXACT [] synonym: "first finger" RELATED [EMAPA:17429] synonym: "fore digit I" EXACT [AAO:0010639] synonym: "fore limb digit 1" EXACT [OBOL:accepted] synonym: "forelimb dewclaw" NARROW SENSU [Wikipedia:Dewclaw] synonym: "hand digit 1" EXACT [MA:0000454] synonym: "hand digit 1" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit 1" EXACT [] synonym: "manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "pollex" EXACT LATIN [Wikipedia:Thumb] synonym: "thumb" NARROW SENSU [] xref: AAO:0010639 xref: EHDAA2:0000511 xref: EMAPA:17429 xref: FMA:24938 xref: GAID:58 xref: MA:0000454 xref: MESH:D013933 xref: NCIT:C52834 xref: SCTID:302540006 xref: SCTID:69603001 xref: UMLS:C0040067 {source="ncithesaurus:Hand_Digit_1"} xref: Wikipedia:Thumb is_a: UBERON:0006048 ! digit 1 is_a: UBERON:0019231 ! manual digit 1 or 5 intersection_of: UBERON:0006048 ! digit 1 intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:5001463 ! manual digit 1 plus metapodial segment relationship: preaxialmost_part_of UBERON:0002398 ! manus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Thumb-up.jpg" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/2/2c/Thumbs_up.jpg" xsd:anyURI property_value: RO:0002173 NCBITaxon:8782 property_value: UBPROP:0000008 "Not present in Anurans (Phenotype RCN Oct 2012)" xsd:string property_value: UBPROP:0000008 "This class represents the standard tetrapod configuration. Wagner proposes that avian digits I,II,III develop from C2,C3,C4. To support this scheme we have separate classes representing the avian digits (here called alula, manual digit, major digit)." xsd:string {scope="NCBITaxon:8782", seeAlso="UBERON:0012260", source="PMID:10220427", source="PhenoscapeRCN"} [Term] id: UBERON:0001464 name: hip namespace: uberon def: "The hip region is located lateral to the gluteal region (i.e. the buttock), inferior to the iliac crest, and overlying the greater trochanter of the thigh bone. In adults, three of the bones of the pelvis have fused into the hip bone which forms part of the hip region. The hip joint, scientifically referred to as the acetabulofemoral joint (art. coxae), is the joint between the femur and acetabulum of the pelvis and its primary function is to support the weight of the body in both static (e.g. standing) and dynamic (e.g. walking or running) postures. [WP,modified]." [Wikipedia:Hip] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "coxa" RELATED LATIN [Wikipedia:Hip] synonym: "hip region" EXACT [FMA:24964] synonym: "regio coxae" EXACT [FMA:24964] xref: BTO:0001457 xref: CALOHA:TS-2226 xref: EFO:0001929 xref: EHDAA2:0000783 xref: EHDAA:5153 xref: EHDAA:6178 xref: EMAPA:17490 xref: FMA:24964 xref: GAID:47 xref: galen:Hip xref: MA:0000045 xref: MESH:D006615 xref: NCIT:C64193 xref: SCTID:302543008 xref: UMLS:C0019552 {source="ncithesaurus:Hip"} xref: VHOG:0000346 xref: Wikipedia:Hip is_a: UBERON:0000475 ! organism subdivision relationship: overlaps UBERON:0001271 {source="FMA-modified"} ! pelvic girdle region relationship: part_of UBERON:0010709 ! pelvic complex property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9f/Hip.jpg" xsd:anyURI property_value: UBPROP:0000003 "The pelvic girdle is never joined by contributions of dermal bone. From its first appearance in placoderms, the pelvic girdle is exclusively endoskeletal. It arose from pterygiophores, perhaps several times, in support of the fin.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000346", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.333", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "coxal" xsd:string property_value: UBPROP:0000012 "See notes for shoulder. in BTO this is part of the abdomen - this creates an inconsistency if limb and abdomen are spatially disjoint" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0001465 name: knee namespace: uberon def: "A segment of the hindlimb that corresponds to the joint connecting a hindlimb stylopod and zeugopod." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "knee region" EXACT [] xref: BTO:0003595 xref: CALOHA:TS-2220 xref: EHDAA2:0000895 xref: EHDAA:5159 xref: EHDAA:6184 xref: EMAPA:17493 xref: FMA:24974 xref: GAID:48 xref: galen:Knee xref: MA:0000046 xref: MESH:D007717 xref: SCTID:361291001 xref: VHOG:0000347 is_a: UBERON:0008784 ! lower limb segment relationship: part_of UBERON:0000978 ! leg property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8d/Male_Knee_by_David_Shankbone.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001466 name: pedal digit namespace: uberon alt_id: UBERON:0000027 def: "A digit that is part of a pes (foot)." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "digit of foot" EXACT [] synonym: "digit of terminal segment of lower limb" EXACT [OBOL:automatic] synonym: "digiti pedis" EXACT PLURAL [FMA:70664, FMA:TA] synonym: "digiti pedis" RELATED LATIN [Wikipedia:Toe] synonym: "digitipedis" RELATED [BTO:0002348] synonym: "digitus pedis" EXACT [] synonym: "foot digit" EXACT [MA:0000048] synonym: "hind digit" EXACT [XAO:0003035] synonym: "hind_digit" EXACT [AAO:0000888] synonym: "hindlimb digit" EXACT [] synonym: "pedal digit (phalangeal portion) plus soft tissue" EXACT COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pes digit" EXACT [] synonym: "toe" EXACT [FMA:25046] xref: AAO:0000888 xref: BTO:0002348 xref: EMAPA:32649 xref: FMA:25046 xref: GAID:44 xref: galen:Toe xref: MA:0000048 xref: NCIT:C33788 xref: SCTID:116667001 xref: UMLS:C0040357 {source="ncithesaurus:Toe"} xref: Wikipedia:Toe xref: XAO:0003035 is_a: UBERON:0002544 ! digit intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0012142 {source="PHENOSCAPE:ni"} ! pedal digitopodium region relationship: part_of UBERON:5001466 ! pedal digit plus metapodial segment property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5e/Toes.jpg" xsd:anyURI [Term] id: UBERON:0001467 name: shoulder namespace: uberon def: "A subdivision of the pectoral complex consisting of the structures in the region of the shoulder joint (which connects the humerus, scapula and clavicle)." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "articulatio humeri" RELATED LATIN [Wikipedia:Shoulder] synonym: "shoulder region" EXACT [] xref: CALOHA:TS-2229 xref: EFO:0003068 xref: EHDAA2:0001834 xref: EHDAA:4180 xref: EHDAA:6228 xref: EMAPA:17421 xref: FMA:25202 xref: GAID:60 xref: galen:Shoulder xref: MA:0000038 xref: MESH:D012782 xref: NCIT:C25203 xref: SCTID:361103004 xref: UMLS:C0037004 {source="ncithesaurus:Shoulder"} xref: VHOG:0000342 xref: Wikipedia:Shoulder is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000475 ! organism subdivision relationship: has_part UBERON:0016884 ! shoulder joint relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: overlaps UBERON:0001421 {source="FMA-modified"} ! pectoral girdle region relationship: part_of UBERON:0010708 ! pectoral complex property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/90/Shoulderjoint.PNG" xsd:anyURI property_value: UBPROP:0000003 "(...) endochondral elements of the early tetrapod shoulder develop from two centers of ossification, giving rise to a scapula and a 'coracoid'.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000342", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.332", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "In FMA, the shoulder is part of the pectoral girdle region. in MA, shoulder structures like shoulder joints, bones, nerves etc are part of the shoulder and the forelimb. E.g. humerus is a shoulder bone" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001468 name: intervertebral joint namespace: uberon def: "The joint between adjacent vertebral bodies. May be composed of the nucleus pulposus, annular ligament, and the anterior and posterior longitudinal ligaments." [http://www.medilexicon.com/medicaldictionary.php?t=87401] synonym: "inter-centrum joint" EXACT [] synonym: "inter-vertebral joint" EXACT [] synonym: "intervertebral symphysis" EXACT [FMA:25511] synonym: "joint of vertebral body" EXACT [FMA:25511] synonym: "vertebral joint" BROAD [] xref: EMAPA:37622 {source="MA:th"} xref: FMA:25511 xref: MA:0001514 xref: NCIT:C49577 xref: SCTID:244512000 xref: UMLS:C1182940 {source="ncithesaurus:Vertebral_Joint"} is_a: UBERON:0002216 {source="FMA"} ! symphysis intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001075 {cardinality="2"} ! bony vertebral centrum relationship: connects UBERON:0001075 {notes="connects successive pairs of centra"} ! bony vertebral centrum relationship: part_of UBERON:0001130 {source="FMA"} ! vertebral column property_value: UBPROP:0000012 "FMA has 'intervertebral joint' as a GAT, and has two distinct classes 'intervertebral symphysis' and 'intervertebral syndesmosis', but note that the latter do not connect the centra" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001469 name: sternoclavicular joint namespace: uberon def: "The sternoclavicular articulation is a double arthrodial joint composed of two portions separated by an articular disc. The parts entering into its formation are the sternal end of the clavicle, the upper and lateral part of the manubrium sterni, and the cartilage of the first rib, visible from the outside as the suprasternal notch. The articular surface of the clavicle is much larger than that of the sternum, and is invested with a layer of cartilage, which is considerably thicker than that on the latter bone. The ligaments of this joint are: Articular capsule Anterior sternoclavicular ligament Posterior sternoclavicular ligament Interclavicular ligament Costoclavicular ligament Articular disk [WP,unvetted]." [Wikipedia:Sternoclavicular_articulation] subset: uberon_slim synonym: "articulatio sternoclavicularis" RELATED LATIN [Wikipedia:Sternoclavicular_articulation] synonym: "sterno clavicular joint" EXACT [] synonym: "sternoclavicular" BROAD [Wikipedia:Sternoclavicular_articulation] synonym: "sternoclavicular articulation" EXACT [Wikipedia:Sternoclavicular_articulation] xref: EMAPA:19203 xref: FMA:25883 xref: GAID:270 xref: MA:0001507 xref: MESH:D013247 xref: NCIT:C33615 xref: SCTID:182165002 xref: UMLS:C0038291 {source="ncithesaurus:Sternoclavicular_Joint"} xref: Wikipedia:Sternoclavicular_articulation is_a: UBERON:0011108 {source="FMA"} ! synovial joint of pectoral girdle is_a: UBERON:0011965 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="Wikipedia"} ! saddle joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000975 ! sternum intersection_of: connects UBERON:0001105 ! clavicle bone relationship: connects UBERON:0000975 {notes="clavicular notch of the manubrium sterni"} ! sternum relationship: connects UBERON:0001105 {notes="sternal end of the clavicle and first rib"} ! clavicle bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3f/Gray325.png" xsd:anyURI [Term] id: UBERON:0001470 name: glenohumeral joint namespace: uberon def: "The glenohumeral joint, commonly known as the shoulder joint, is a multiaxial synovial ball and socket joint and involves articulation between the glenoid fossa of the scapula (shoulder blade) and the head of the humerus (upper arm bone). [WP,unvetted]." [Wikipedia:Glenohumeral_joint] subset: uberon_slim synonym: "articulatio humeri" EXACT LATIN [FMA:25912, FMA:TA] synonym: "humeral joint" EXACT [FMA:25912] synonym: "humeroscapular joint" RELATED [Wikipedia:Glenohumeral_joint] synonym: "joint of shoulder" BROAD [OBOL:automatic] synonym: "shoulder joint" BROAD [MA:0000459] xref: EMAPA:19105 xref: FMA:25912 xref: GAID:269 xref: galen:ShoulderJoint xref: MA:0000459 xref: MESH:D012785 xref: NCIT:C33548 xref: SCTID:182168000 xref: UMLS:C0037009 {source="ncithesaurus:Shoulder_Joint"} xref: VHOG:0001002 xref: Wikipedia:Glenohumeral_joint is_a: UBERON:0011108 ! synovial joint of pectoral girdle is_a: UBERON:0011139 {source="FMA"} ! synovial limb joint is_a: UBERON:0016884 ! shoulder joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000976 ! humerus intersection_of: connects UBERON:0006849 ! scapula relationship: adjacent_to UBERON:0006657 ! glenoid fossa relationship: connects UBERON:0000976 ! humerus relationship: connects UBERON:0006849 ! scapula relationship: part_of UBERON:0004753 ! scapulocoracoid property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a3/Gray327.png" xsd:anyURI property_value: editor_note "note that in this ontology 'glenoid fossa' is a cavity (consistent with FMA) - consider adding a class for the surface of the scapula that is adjacent to this cavity, and making a more explicit connects relationship" xsd:string property_value: UBPROP:0000012 "in FMA, this is part of the bony pectoral girdle, alongside the skeleton of pectoral girdle" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001474 name: bone element namespace: uberon def: "Skeletal element that is composed of bone tissue." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/277, PSPUB:0000170, VSAO:0000057] subset: efo_slim subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bone" RELATED [AEO:0000082, BTO:0000140, MA:0001459, VHOG:0001190] synonym: "bone organ" EXACT [FMA:5018] synonym: "bones" RELATED PLURAL [ZFA:0001514] xref: AAO:0000047 xref: AEO:0000082 xref: BTO:0000140 xref: CALOHA:TS-0088 xref: EFO:0000298 xref: EHDAA2:0003082 xref: EMAPA:32782 xref: ENVO:00002039 xref: EV:0100140 xref: FMA:30317 xref: FMA:5018 xref: GAID:92 xref: galen:Bone xref: MA:0001459 xref: MAT:0000299 xref: MIAA:0000299 xref: NCIT:C12366 xref: SCTID:90780006 xref: TAO:0001514 xref: UMLS:C0262950 {source="ncithesaurus:Bone"} xref: VHOG:0001190 xref: VSAO:0000057 xref: Wikipedia:Bone xref: XAO:0000169 xref: ZFA:0001514 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004765 ! skeletal element intersection_of: UBERON:0004765 ! skeletal element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue disjoint_from: UBERON:0001630 ! muscle organ disjoint_from: UBERON:0005090 ! muscle structure disjoint_from: UBERON:0010538 ! paired limb/fin segment relationship: composed_primarily_of UBERON:0002481 {source="VSAO-modified"} ! bone tissue relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: RO:0002171 UBERON:0001015 property_value: RO:0002171 UBERON:0001630 property_value: RO:0002171 UBERON:0002385 property_value: UBPROP:0000001 "Also called osseous tissue, (Latin: os). Is a type of hard endoskeletal connective tissue found in many vertebrate animals. Bone is the main tissue of body organs that support body structures, protect internal organs, (in conjunction with muscles) facilitate movement; and are involved with cell formation, calcium metabolism, and mineral storage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000047", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "Portion of tissue which is calcified connective tissue making up the structural elements of the skeletal system.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001514", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Skeletal element that is composed of bone tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000057", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000047", ontology="AAO"} property_value: UBPROP:0000003 "The 'new animal phylogeny' reveals that many of the groups known to biomineralize sit among close relatives that do not, and it favours an interpretation of convergent or parallel evolution for biomineralization in animals. (...) Whether this 'biomineralization toolkit'of genes reflects a parallel co-option of a common suite of genes or the inheritance of a skeletogenic gene regulatory network from a biomineralizing common ancestor remains an open debate.[debated][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001190", ontology="VHOG", source="DOI:10.1159/000324245 Murdock DJ, Donoghue PC, Evolutionary Origins of Animal Skeletal Biomineralization. Cells Tissues Organs (2011)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001476 name: deltoid namespace: uberon def: "A muscle of shoulder which attaches to the scapula, clavicle and humerus.[FMA,generalized]." [FMA:32521, http://orcid.org/0000-0002-6601-2165] comment: We use a generic definition that includes the deltoideus as represented in AAO: 'Muscle which originates as three heads, the pars externalis, pars clavicularis, and pars scapularis. The pars externalis originates from the lateral border of the omosternum and inserts on the distal portion of the humerus. The pars clavicularis originates from the ventro-lateral surface of the clavicle and inserts on the deltoid crest of the humerus. The pars scapularis originates from the lateral surface of the clavicle and inserts on the deltoid crest of the humerus'. Kardong: Dorsal group subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "common shoulder muscle" RELATED [Wikipedia:Deltoid_muscle] synonym: "deltoid muscle" EXACT [Wikipedia:Deltoid_muscle] synonym: "deltoideus" RELATED [Wikipedia:Deltoid_muscle] synonym: "deltoideus muscle" RELATED [Wikipedia:Deltoid_muscle] synonym: "m. deltoideus" EXACT [AAO:0010716] synonym: "musculus deltoideus" EXACT [Wikipedia:Deltoid_muscle] synonym: "musculus deltoideus" RELATED LATIN [Wikipedia:Deltoid_muscle] xref: AAO:0010716 xref: EFO:0001412 xref: EHDAA2:0000339 xref: EMAPA:18177 xref: FMA:32521 xref: MA:0002286 xref: NCIT:C32446 xref: SCTID:181620007 xref: UMLS:C0224234 {source="ncithesaurus:Deltoid"} xref: VHOG:0000846 xref: Wikipedia:Deltoid_muscle is_a: UBERON:0001482 {source="FMA"} ! muscle of shoulder is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0034908 ! scapular muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0000976 ! humerus intersection_of: attaches_to UBERON:0001105 ! clavicle bone intersection_of: attaches_to UBERON:0006849 ! scapula relationship: attaches_to UBERON:0000976 ! humerus relationship: attaches_to UBERON:0001105 ! clavicle bone relationship: attaches_to UBERON:0002498 {source="FMA"} ! deltopectoral crest relationship: develops_from UBERON:0006219 {source="EHDAA2"} ! deltoid pre-muscle mass relationship: has_muscle_antagonist UBERON:0001112 {source="dbpedia"} ! latissimus dorsi muscle relationship: has_muscle_insertion UBERON:0002498 {notes="deltoid tuberosity of humerus", source="dbpedia"} ! deltopectoral crest relationship: has_muscle_origin UBERON:0001105 {notes="the anterior border and upper surface of the lateral third of the clavicle acromion spine of the scapula", source="dbpedia"} ! clavicle bone relationship: has_muscle_origin UBERON:0002497 {notes="the anterior border and upper surface of the lateral third of the clavicle acromion spine of the scapula", source="dbpedia"} ! acromion relationship: has_muscle_origin UBERON:0006849 {notes="the anterior border and upper surface of the lateral third of the clavicle acromion spine of the scapula", source="dbpedia"} ! scapula relationship: innervated_by UBERON:0001493 {source="dbpedia"} ! axillary nerve relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/93/Deltoideus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Muscle which originates as three heads, the pars externalis, pars clavicularis, and pars scapularis. The pars externalis originates from the lateral border of the omosternum and inserts on the distal portion of the humerus. The pars clavicularis originates from the ventro-lateral surface of the clavicle and inserts on the deltoid crest of the humerus. The pars scapularis originates from the lateral surface of the clavicle and inserts on the deltoid crest of the humerus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010716", ontology="AAO", source="AAO:MEJ"} [Term] id: UBERON:0001479 name: sesamoid bone namespace: uberon def: "A sesamoid element that is composed of bone tissue." [http://orcid.org/0000-0002-6601-2165] comment: Sesamoids are often endochondral replacement elements and in addition to bone tissue, may also be composed of articular cartilage, fibrocartilage, hyaline cartilage, and calcified cartilage.[VSAO] subset: uberon_slim synonym: "ossa sesamoidea" EXACT LATIN [Wikipedia:Sesamoid_bone] synonym: "sesamoid" BROAD [] xref: AEO:0000086 xref: EHDAA2:0003086 xref: EMAPA:36620 xref: FMA:32672 xref: GAID:210 xref: galen:SessamoidBone xref: MA:0001375 xref: MESH:D012716 xref: NCIT:C33541 xref: SCTID:362914002 xref: UMLS:C0036846 {source="ncithesaurus:Sesamoid_Bone"} xref: Wikipedia:Sesamoid_bone is_a: UBERON:0013630 {source="UBERON:cjm"} ! short bone is_a: UBERON:0013631 ! sesamoid element intersection_of: UBERON:0013631 ! sesamoid element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b3/Gray350.png" xsd:anyURI [Term] id: UBERON:0001480 name: proximal carpal bone namespace: uberon def: "A carpal bone that proximally_connected_to a forelimb zeugopod skeleton." [OBOL:automatic] xref: EMAPA:36164 xref: FMA:33302 xref: MA:0002557 xref: SCTID:306715004 is_a: UBERON:0001435 ! carpal bone is_a: UBERON:0014395 ! proximal mesopodial bone is_a: UBERON:0015078 ! proximal carpal endochondral element intersection_of: UBERON:0015078 ! proximal carpal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015079 ! proximal carpal cartilage [Term] id: UBERON:0001481 name: distal carpal bone namespace: uberon def: "A distal carpal endochondral element that is composed primarily of a bone tissue." [OBOL:automatic] synonym: "distal carpal" EXACT [AAO:0000847] xref: AAO:0000847 xref: EMAPA:36168 xref: FMA:33303 xref: MA:0002558 xref: SCTID:306716003 is_a: UBERON:0001435 ! carpal bone is_a: UBERON:0015068 ! distal carpal endochondral element is_a: UBERON:0018102 ! distal mesopodial bone intersection_of: UBERON:0015068 ! distal carpal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015069 ! distal carpal cartilage element relationship: distally_connected_to UBERON:0002374 ! metacarpal bone property_value: UBPROP:0000001 "Series of elements that articulate with the metacarpals.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000847", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000008 "Primitively, each of the distal bones appears to have articulated with a single metacarpal" xsd:string {source="WP"} [Term] id: UBERON:0001482 name: muscle of shoulder namespace: uberon def: "Any muscle organ that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "muscle organ of shoulder" EXACT [OBOL:automatic] synonym: "shoulder muscle" EXACT [] synonym: "shoulder muscle organ" EXACT [OBOL:automatic] xref: EMAPA:36154 xref: FMA:33531 xref: MA:0000633 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0003461 ! shoulder bone relationship: attaches_to UBERON:0003461 ! shoulder bone relationship: overlaps UBERON:0001467 ! shoulder relationship: part_of UBERON:0004476 {source="prolog"} ! musculature of shoulder property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001483 name: skin of shoulder namespace: uberon def: "A zone of skin that is part of a shoulder region." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "shoulder skin" EXACT [] synonym: "shoulder zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of shoulder" EXACT [OBOL:automatic] xref: EMAPA:18059 xref: FMA:34830 xref: MA:0000635 xref: SCTID:244131002 is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001467 ! shoulder relationship: part_of UBERON:0001467 ! shoulder property_value: UBPROP:0000012 "in MA this is a subclass of forelimb skin, but this violates part-disjointness in Uberon" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001484 name: articular capsule namespace: uberon def: "An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]." [Wikipedia:Articular_capsule] subset: organ_slim subset: uberon_slim synonym: "capsula articularis" EXACT LATIN [FMA:34836, FMA:TA] synonym: "capsulae articulares" RELATED LATIN [Wikipedia:Articular_capsule] synonym: "fibrous capsule of joint" EXACT [] synonym: "joint capsule" EXACT [] synonym: "joint fibrous capsule" EXACT [] xref: EMAPA:37621 {source="MA:th"} xref: FMA:34836 xref: GAID:263 xref: galen:JointCapsule xref: MA:0001519 xref: MESH:D017746 xref: NCIT:C32259 xref: NCIT:C84388 xref: SCTID:182238002 xref: UMLS:C0206207 {source="ncithesaurus:Joint_Capsule"} xref: Wikipedia:Articular_capsule is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000094 ! membrane organ intersection_of: UBERON:0000094 ! membrane organ intersection_of: has_part UBERON:0007616 ! layer of synovial tissue intersection_of: surrounds UBERON:0002217 ! synovial joint relationship: has_part UBERON:0007616 ! layer of synovial tissue relationship: surrounds UBERON:0002217 ! synovial joint property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/19/Joint.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4a/Gray299.png" xsd:anyURI property_value: UBPROP:0000012 "check ncita" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0001485 name: knee joint namespace: uberon def: "The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation[WP,unvetted]." [Wikipedia:Knee] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "articulatio genus" RELATED LATIN [Wikipedia:Knee] synonym: "joint of knee" EXACT [OBOL:automatic] xref: EFO:0001957 xref: EMAPA:19137 xref: FMA:35175 xref: GAID:114 xref: galen:KneeJoint xref: MA:0000471 xref: MESH:D007719 xref: NCIT:C32898 xref: SCTID:182204005 xref: UMLS:C0022745 {source="ncithesaurus:Knee_Joint"} xref: VHOG:0001003 xref: Wikipedia:Knee is_a: UBERON:0003840 ! hindlimb joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0000981 ! femur intersection_of: connects UBERON:0002446 ! patella relationship: connects UBERON:0000979 ! tibia relationship: connects UBERON:0000981 ! femur relationship: connects UBERON:0002446 ! patella relationship: develops_from UBERON:0006256 {evidence="definitional"} ! knee joint primordium relationship: part_of UBERON:0001465 ! knee property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/ca/Knee.agr.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001486 name: hip joint namespace: uberon def: "A synovial joint that connects the femur to the acetbulum of the innominate bone." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "articulatio coxofemoralis" EXACT [FMA:35178] synonym: "coxal articulation" RELATED [Wikipedia:Hip] synonym: "femoro-iliac joint" EXACT [] xref: BTO:0001502 xref: EMAPA:19136 xref: FMA:35178 xref: GAID:262 xref: galen:HipJoint xref: MA:0000470 xref: MESH:D006621 xref: NCIT:C32742 xref: SCTID:182201002 xref: UMLS:C0019558 {source="ncithesaurus:Hip_Joint"} xref: VHOG:0001001 xref: Wikipedia:Hip#Articulation is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011107 {source="FMA"} ! synovial joint of pelvic girdle intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000981 ! femur intersection_of: connects UBERON:0001269 ! acetabular part of hip bone relationship: connects UBERON:0000981 ! femur relationship: connects UBERON:0001269 ! acetabular part of hip bone relationship: develops_from UBERON:0006244 {evidence="definitional"} ! hip joint primordium relationship: part_of UBERON:0001464 {source="FMA"} ! hip [Term] id: UBERON:0001487 name: pes joint namespace: uberon def: "A skeletal joint that is part of a pes [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "articulationes pedis" EXACT LATIN [FMA:71349, FMA:TA] synonym: "foot joint" EXACT [] synonym: "hind limb autopod joint" EXACT [OBOL:automatic] synonym: "joint of pes" EXACT [] synonym: "joint of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "joints of foot" EXACT PLURAL [FMA:71349] synonym: "pedal joint" EXACT [] xref: EMAPA:32949 xref: FMA:35194 xref: GAID:256 xref: MA:0000464 xref: MESH:D033023 xref: SCTID:244555001 xref: Wikipedia:Joints_of_foot is_a: UBERON:0003840 ! hindlimb joint is_a: UBERON:0003841 ! autopod joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0002387 ! pes property_value: editor_note "TODO check FMA - use the set class for now" xsd:string property_value: UBPROP:0000202 FMA:71349 [Term] id: UBERON:0001488 name: ankle joint namespace: uberon def: "A joint that connects the hindlimb autopod and zeugopod skeletons." [https://orcid.org/0000-0002-6601-2165, MESH:A02.835.583.378.062, Wikipedia:Ankle] subset: efo_slim subset: uberon_slim synonym: "gambrel" NARROW [Wikipedia:Hock_(anatomy)] synonym: "hock" NARROW [Wikipedia:Hock_(anatomy)] synonym: "hock joint" NARROW [Wikipedia:Hock_(anatomy)] synonym: "mortise joint" RELATED [BTO:0004706] synonym: "talocrural articulation" RELATED [Wikipedia:Ankle] synonym: "talocrural joint" RELATED [Wikipedia:Ankle] synonym: "talotibial joint" NARROW [Wikipedia:Ankle] xref: BTO:0004706 xref: EMAPA:35126 xref: FMA:35195 xref: GAID:257 xref: galen:AnkleJoint xref: MA:0000463 xref: MESH:D000843 xref: NCIT:C32078 xref: SCTID:182212002 xref: UMLS:C0003087 {source="ncithesaurus:Ankle_Joint"} xref: Wikipedia:Ankle is_a: UBERON:0003840 ! hindlimb joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001445 ! skeleton of pes intersection_of: connects UBERON:0010720 ! hindlimb zeugopod skeleton relationship: connects UBERON:0000979 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! tibia relationship: connects UBERON:0001445 ! skeleton of pes relationship: connects UBERON:0001446 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! fibula relationship: connects UBERON:0010720 ! hindlimb zeugopod skeleton relationship: overlaps UBERON:0002387 ! pes property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/b/bf/Ankle_en.svg" xsd:anyURI property_value: UBPROP:0000008 "todo - accurately represent different types of ankle joint" xsd:string [Term] id: UBERON:0001489 name: manus joint namespace: uberon def: "A skeletal joint that is part of a manus (hand) [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "articulationes manus" EXACT LATIN [FMA:71345, FMA:TA] synonym: "hand joint" EXACT [] synonym: "joint of hand" EXACT [] synonym: "joint of manus" EXACT [] synonym: "joint of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "manual joint" EXACT [] xref: EMAPA:32641 xref: MA:0000452 xref: SCTID:244546004 xref: Wikipedia:Joints_of_hand is_a: UBERON:0003839 ! forelimb joint is_a: UBERON:0003841 ! autopod joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0002398 ! manus property_value: editor_note "TODO check FMA - use the set class for now" xsd:string property_value: UBPROP:0000202 FMA:71345 [Term] id: UBERON:0001490 name: elbow joint namespace: uberon def: "A joint that connects the forelimb zeugopod and stylopod skeletons[Obol]." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Elbow] subset: pheno_slim subset: uberon_slim synonym: "articulatio cubiti" EXACT LATIN [] synonym: "cubital region joint" EXACT [OBOL:automatic] synonym: "joint of cubital region" EXACT [OBOL:automatic] synonym: "joint of elbow" EXACT [OBOL:automatic] xref: EMAPA:19102 xref: FMA:35289 xref: GAID:253 xref: galen:ElbowJoint xref: MA:0000451 xref: MESH:D004551 xref: NCIT:C32497 xref: SCTID:182169008 xref: UMLS:C0013770 {source="ncithesaurus:Elbow_Joint"} xref: VHOG:0000997 xref: Wikipedia:Elbow is_a: UBERON:0003839 ! forelimb joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000976 ! humerus intersection_of: connects UBERON:0010703 ! forelimb zeugopod skeleton relationship: connects UBERON:0000976 ! humerus relationship: connects UBERON:0010703 ! forelimb zeugopod skeleton relationship: develops_from UBERON:0006224 {evidence="definitional"} ! elbow joint primordium relationship: part_of UBERON:0001461 ! elbow property_value: UBPROP:0000008 "In human anatomy, the elbow joint is a compound joint that actually comprises three separate joints: the joints connecting the upper and lower arm: 1) Articulatio humero-ulnaris and 2) Articulatio humero-radialis as well as the proximal joint connecting the forarm bones: 3) Articulatio radio-ulnaris proximalis" xsd:string {source="HP"} [Term] id: UBERON:0001491 name: wrist joint namespace: uberon def: "A joint connecting the forelimb zeugopod skeleton with the carpal skeleton." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/?group_id=76834&atid=1205376, Wikipedia:Wrist] subset: uberon_slim synonym: "carpal region joint" EXACT [OBOL:automatic] synonym: "joint of carpal region" EXACT [OBOL:automatic] synonym: "joint of wrist" EXACT [] synonym: "radiocarpal joint" NARROW INCONSISTENT [FMA:35291] xref: EMAPA:19205 xref: FMA:321842 xref: GAID:274 xref: galen:WristJoint xref: MA:0000460 xref: MESH:D014955 xref: NCIT:C33894 xref: SCTID:182178002 xref: UMLS:C1322271 {source="ncithesaurus:Wrist_Joint"} xref: Wikipedia:Wrist is_a: UBERON:0001489 ! manus joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0009880 ! carpal skeleton intersection_of: connects UBERON:0010703 ! forelimb zeugopod skeleton relationship: connects UBERON:0009880 ! carpal skeleton relationship: connects UBERON:0010703 ! forelimb zeugopod skeleton relationship: part_of UBERON:0004452 ! carpal region property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/4a/Human_wrist.png" xsd:anyURI property_value: UBPROP:0000012 "in FMA this includes radio-carpal and radio-ulnar *ligaments*" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001493 name: axillary nerve namespace: uberon def: "The axillary nerve is a nerve of the human body, that comes off the posterior cord of the brachial plexus at the level of the axilla (armpit) and carries nerve fibers from C5 and C6. The axillary nerve travels through the quadrangular space with the posterior circumflex humeral artery and vein. [WP,unvetted]." [Wikipedia:Axillary_nerve] subset: human_reference_atlas subset: uberon_slim synonym: "auxillery nerve" RELATED [Wikipedia:Axillary_nerve] synonym: "circumflex humeral nerve" EXACT [] synonym: "circumflex nerve" RELATED [Wikipedia:Axillary_nerve] synonym: "nervus axillaris" RELATED LATIN [Wikipedia:Axillary_nerve] xref: EMAPA:18802 xref: FMA:37072 xref: MA:0001166 xref: NCIT:C52817 xref: SCTID:181009006 xref: UMLS:C0228885 {source="ncithesaurus:Axillary_Nerve"} xref: Wikipedia:Axillary_nerve is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0003433 ! arm nerve relationship: innervates UBERON:0009472 ! axilla relationship: part_of UBERON:0001814 {source="MA"} ! brachial nerve plexus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ea/Brachial_plexus_2.svg" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/d4/Brachial_plexus.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001496 name: ascending aorta namespace: uberon def: "The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]." [GO:0035905, Wikipedia:Ascending_aorta] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "aorta ascendens" RELATED LATIN [Wikipedia:Ascending_aorta] synonym: "ascending thoracic aorta" EXACT [EMAPA:17014] synonym: "pars ascendens aortae" EXACT [] synonym: "pars ascendens aortae" RELATED LATIN [Wikipedia:Ascending_aorta] xref: EHDAA2:0000147 xref: EHDAA:9828 xref: EMAPA:17014 xref: FMA:3736 xref: MA:0002570 xref: NCIT:C32150 xref: SCTID:181299009 xref: UMLS:C0003956 {source="ncithesaurus:Ascending_Aorta"} xref: Wikipedia:Ascending_aorta is_a: UBERON:0001515 ! thoracic aorta relationship: contributes_to_morphology_of UBERON:0001515 ! thoracic aorta relationship: develops_from UBERON:0005338 {source="EHDAA2"} ! outflow tract aortic component relationship: has_developmental_contribution_from UBERON:0002061 ! truncus arteriosus relationship: has_developmental_contribution_from UBERON:0005432 ! aortic sac relationship: part_of UBERON:0001515 ! thoracic aorta property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001497 name: muscle of pelvic girdle namespace: uberon alt_id: UBERON:0003271 def: "Any muscle organ that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "girdle-pelvic muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of girdle-pelvic" EXACT [OBOL:automatic] synonym: "muscle organ of pelvic girdle" EXACT [OBOL:automatic] synonym: "muscle organ of pelvic girdle bone" EXACT [OBOL:automatic] synonym: "pelvic girdle muscle" EXACT [] synonym: "pelvic girdle muscle organ" EXACT [OBOL:automatic] synonym: "pelvic girdle skeletal muscle" EXACT [EMAPA:18185] xref: EHDAA:8326 xref: EMAPA:18184 xref: EMAPA:18185 xref: FMA:37367 xref: MA:0000537 xref: RETIRED_EHDAA2:0001430 is_a: UBERON:0001325 ! muscle of pelvis is_a: UBERON:0010890 ! pelvic complex muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0001271 ! pelvic girdle region relationship: part_of UBERON:0004470 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! musculature of pelvic girdle property_value: UBPROP:0000012 "Note that in MA, this is a subclass of pelvis muscle; in FMA this is a hindlimb muscle, but recall in FMA hindlimb includes the girdle." xsd:string {external_ontology="MA"} [Term] id: UBERON:0001498 name: muscle of pes namespace: uberon def: "Any muscle organ that is part of a pes [Automatically generated definition]." [OBOL:automatic] synonym: "foot muscle" EXACT [] synonym: "foot muscle organ" EXACT [OBOL:automatic] synonym: "muscle of foot" EXACT [FMA:37369] synonym: "muscle organ of foot" EXACT [OBOL:automatic] xref: BTO:0000477 xref: EMAPA:36160 xref: FMA:37369 xref: MA:0000652 xref: SCTID:67240005 is_a: UBERON:0003663 ! hindlimb muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0004488 {source="prolog"} ! musculature of pes [Term] id: UBERON:0001499 name: muscle of arm namespace: uberon alt_id: UBERON:0003272 def: "A muscle organ that is part of an arm [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "arm muscle" EXACT [MA:0000594] synonym: "arm muscle system" RELATED [EHDAA2:0000141] synonym: "arm skeletal muscle" EXACT [OBOL:automatic] synonym: "arm skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "muscle of upper arm or lower arm" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "upper arm / lower arm muscle" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA:8277 xref: EMAPA:36053 xref: MA:0000594 xref: RETIRED_EHDAA2:0000142 is_a: UBERON:0003662 ! forelimb muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0004474 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! musculature of arm property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000013 "See notes on UBERON:0001460 for possible terminological confusion over term 'arm'. MA uses this consistent with uberon (forelimb muscle is subdivided into shoulder, arm and hand)" xsd:string [Term] id: UBERON:0001500 name: muscle of manus namespace: uberon def: "Any muscle organ that is part of a manus [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "hand muscle" EXACT [MA:0000628] synonym: "manus muscle" EXACT [] synonym: "manus muscle organ" EXACT [OBOL:automatic] synonym: "muscle of hand" EXACT [FMA:37372] synonym: "muscle organ of manus" EXACT [OBOL:automatic] xref: EMAPA:32644 xref: FMA:37372 xref: MA:0000628 xref: SCTID:110540008 is_a: UBERON:0003662 ! forelimb muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0004489 {source="prolog"} ! musculature of manus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001508 name: arch of aorta namespace: uberon def: "The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery." [ISBN:0-683-40008-8, MP:0004113] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "aortic arch" RELATED [FMA:3768] synonym: "arcus aortae" EXACT LATIN [FMA:3768, FMA:TA] synonym: "thoracic aorta" RELATED [GAID:471] xref: BTO:0000157 xref: EFO:0002526 xref: EHDAA2:0000132 xref: EMAPA:17613 xref: FMA:3768 xref: GAID:471 xref: MA:0000475 xref: SCTID:181300001 xref: VHOG:0001196 xref: Wikipedia:Arch_of_aorta is_a: UBERON:0001515 ! thoracic aorta relationship: connected_to UBERON:0001496 ! ascending aorta relationship: contributes_to_morphology_of UBERON:0001515 ! thoracic aorta relationship: develops_from UBERON:0003121 {notes="left arch 4 in human", source="embryology.ch"} ! pharyngeal arch artery 4 relationship: has_developmental_contribution_from UBERON:0005432 ! aortic sac relationship: has_developmental_contribution_from UBERON:0005613 ! left dorsal aorta relationship: part_of UBERON:0001515 ! thoracic aorta property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: IAO:0000232 "Do not confuse with aortic arch" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The curving portion between the ascending aorta and the descending aorta, giving rise to the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001196", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/arch+of+aorta"} property_value: UBPROP:0000003 "The double systemic arch arches (left and right) present in amphibians and reptiles become reduced to a single systemic arch - the right in birds, the left in mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001196", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.460 and p.461 Figure 12.20", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "birds have right aortic arch, mammals left." xsd:string [Term] id: UBERON:0001510 name: skin of knee namespace: uberon def: "A zone of skin that is part of a knee [Automatically generated definition]." [OBOL:automatic] synonym: "knee skin" EXACT [] synonym: "knee zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of knee" EXACT [OBOL:automatic] xref: EMAPA:18151 xref: FMA:37800 xref: MA:0000668 xref: NCIT:C64859 xref: SCTID:181552001 xref: UMLS:C0222275 {source="ncithesaurus:Knee_Skin"} is_a: UBERON:0001511 ! skin of leg intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001465 ! knee relationship: part_of UBERON:0001465 ! knee [Term] id: UBERON:0001511 name: skin of leg namespace: uberon def: "A zone of skin that is part of a leg [Automatically generated definition]." [OBOL:automatic] synonym: "leg skin" EXACT [] synonym: "leg zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of leg" EXACT [OBOL:automatic] xref: EMAPA:18156 xref: EMAPA:18159 xref: EMAPA:37352 {source="MA:th"} xref: FMA:37828 xref: MA:0000674 xref: NCIT:C52749 xref: UMLS:C0222279 {source="ncithesaurus:Leg_Skin"} is_a: UBERON:0003532 ! hindlimb skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0000978 ! leg [Term] id: UBERON:0001512 name: skin of ankle namespace: uberon def: "A zone of skin that is part of an ankle [Automatically generated definition]." [OBOL:automatic] synonym: "ankle skin" EXACT [] synonym: "ankle zone of skin" EXACT [OBOL:automatic] synonym: "tarsal region skin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "zone of skin of ankle" EXACT [OBOL:automatic] xref: EMAPA:37353 {source="MA:th"} xref: FMA:37831 xref: MA:0000641 xref: NCIT:C52751 xref: SCTID:181560000 xref: UMLS:C0222286 {source="ncithesaurus:Ankle_Skin"} is_a: UBERON:0001513 ! skin of pes intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0004454 ! tarsal region relationship: part_of UBERON:0004454 ! tarsal region [Term] id: UBERON:0001513 name: skin of pes namespace: uberon def: "A zone of skin that is part of a pes [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "foot skin" EXACT [] synonym: "skin of foot" EXACT [FMA:37834] synonym: "skin of hind-paw" NARROW SENSU [EMAPA:18504] xref: EMAPA:18504 xref: FMA:37834 xref: MA:0000654 xref: NCIT:C52750 xref: SCTID:181529000 xref: UMLS:C0222289 {source="ncithesaurus:Foot_Skin"} is_a: UBERON:0003532 {source="MA"} ! hindlimb skin is_a: UBERON:0015790 ! autopod skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0002387 ! pes [Term] id: UBERON:0001514 name: descending aorta namespace: uberon def: "The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]." [GO:0035906, Wikipedia:Descending_aorta] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "aorta descendens" RELATED LATIN [Wikipedia:Descending_aorta] synonym: "pars descendens aortae" EXACT [FMA:3784] synonym: "pars descendens aortae" RELATED LATIN [Wikipedia:Descending_aorta] xref: EMAPA:18606 xref: FMA:3784 xref: MA:0002571 xref: NCIT:C32455 xref: SCTID:261399002 xref: UMLS:C0011666 {source="ncithesaurus:Descending_Aorta"} xref: Wikipedia:Descending_aorta is_a: UBERON:0005800 {source="FMA"} ! section of aorta relationship: connected_to UBERON:0001508 ! arch of aorta relationship: develops_from UBERON:0005805 {source="Wikipedia"} ! dorsal aorta relationship: has_developmental_contribution_from UBERON:0005613 ! left dorsal aorta relationship: has_developmental_contribution_from UBERON:0005622 ! right dorsal aorta property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000011 "results from fusion of left and right dorsal aortae" xsd:string [Term] id: UBERON:0001515 name: thoracic aorta namespace: uberon def: "The part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." [http://www.medterms.com, MP:0010468] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "aorta thoracalis" RELATED LATIN [Wikipedia:Thoracic_aorta] synonym: "aorta thoracica" EXACT LATIN [FMA:3786, FMA:TA] synonym: "pars thoracica aortae" RELATED LATIN [Wikipedia:Thoracic_aorta] synonym: "thoracic part of aorta" EXACT [] xref: BTO:0000157 xref: EFO:0002525 xref: EMAPA:18603 xref: FMA:3786 xref: GAID:471 xref: galen:ThoracicAorta xref: MA:0002569 xref: MESH:D001013 xref: NCIT:C33766 xref: SCTID:302510009 xref: UMLS:C1522460 {source="ncithesaurus:Thoracic_Aorta"} xref: Wikipedia:Thoracic_aorta is_a: UBERON:0005800 {source="FMA"} ! section of aorta intersection_of: UBERON:0005800 ! section of aorta intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: contributes_to_morphology_of UBERON:0000947 ! aorta relationship: part_of UBERON:0000915 ! thoracic segment of trunk property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/75/Gray530.png" xsd:anyURI [Term] id: UBERON:0001516 name: abdominal aorta namespace: uberon def: "Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]." [BTO:0002976, Wikipedia:Abdominal_aorta] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "abdominal part of aorta" EXACT [FMA:3789] synonym: "abdominal part of aorta" RELATED [BTO:0002976] synonym: "aorta abdominalis" RELATED LATIN [BTO:0002976, Wikipedia:Abdominal_aorta] synonym: "descending abdominal aorta" EXACT [FMA:3789] synonym: "pars abdominalis aortae" EXACT [FMA:3789] synonym: "pars abdominalis aortae" RELATED LATIN [BTO:0002976, Wikipedia:Abdominal_aorta] xref: BTO:0002976 xref: EFO:0002524 xref: EMAPA:17856 xref: FMA:3789 xref: GAID:470 xref: galen:AbdominalAorta xref: MA:0000474 xref: MESH:D001012 xref: NCIT:C32038 xref: SCTID:244231007 xref: UMLS:C0003484 {source="ncithesaurus:Abdominal_Aorta"} xref: Wikipedia:Abdominal_aorta is_a: UBERON:0005800 ! section of aorta relationship: connected_to UBERON:0002345 ! descending thoracic aorta relationship: contributes_to_morphology_of UBERON:0001514 ! descending aorta relationship: overlaps UBERON:0000916 ! abdomen relationship: part_of UBERON:0001514 {source="FMA"} ! descending aorta property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/af/Gray531.png" xsd:anyURI property_value: editor_note "Many of the branches of the abdominal aorta in mammals may be branches of the dorsal aorta in other vertebrates" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001517 name: skin of elbow namespace: uberon alt_id: UBERON:0003399 def: "A zone of skin that is part of a elbow [Automatically generated definition]." [OBOL:automatic] synonym: "cubital region zone of skin" EXACT [OBOL:automatic] synonym: "elbow skin" EXACT [] synonym: "elbow zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of cubital region" EXACT [OBOL:automatic] synonym: "zone of skin of elbow" EXACT [OBOL:automatic] xref: EMAPA:18051 xref: FMA:38250 xref: MA:0000610 xref: NCIT:C52755 xref: SCTID:181534001 xref: UMLS:C0222213 {source="ncithesaurus:Elbow_Skin"} is_a: UBERON:0002427 ! arm skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001461 ! elbow relationship: part_of UBERON:0001461 ! elbow [Term] id: UBERON:0001518 name: skin of wrist namespace: uberon def: "A zone of skin that is part of a wrist [Automatically generated definition]." [OBOL:automatic] synonym: "carpal region zone of skin" EXACT [OBOL:automatic] synonym: "wrist skin" EXACT [] synonym: "wrist zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of carpal region" EXACT [OBOL:automatic] synonym: "zone of skin of wrist" EXACT [OBOL:automatic] xref: EMAPA:37351 {source="MA:th"} xref: FMA:38280 xref: MA:0000638 xref: NCIT:C52752 xref: SCTID:181540008 xref: UMLS:C0222223 {source="ncithesaurus:Wrist_Skin"} is_a: UBERON:0001519 ! skin of manus intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0004452 ! carpal region relationship: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0001519 name: skin of manus namespace: uberon def: "A zone of skin that is part of a manus [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "hand skin" EXACT [MA:0000630] synonym: "manus skin" EXACT [] synonym: "skin of fore-paw" NARROW SENSU [EMAPA:18486] synonym: "skin of hand" EXACT [FMA:38295] xref: EMAPA:18486 xref: FMA:38295 xref: MA:0000630 xref: NCIT:C52753 xref: SCTID:181527003 xref: UMLS:C0222224 {source="ncithesaurus:Hand_Skin"} is_a: UBERON:0003531 ! forelimb skin is_a: UBERON:0015790 ! autopod skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0002398 ! manus [Term] id: UBERON:0001528 name: radio-ulnar joint namespace: uberon def: "A joint that connects the radius and the ulna. Examples: proximal and distal radio-ulnar joints." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "articulation of the radus and ulna" EXACT [] synonym: "radioulnar articulation" RELATED [] synonym: "radioulnar joint" EXACT [FMA:38863] xref: EMAPA:19206 xref: FMA:38863 xref: MA:0003145 xref: SCTID:264167003 is_a: UBERON:0003839 ! forelimb joint is_a: UBERON:0011139 {source="FMA"} ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001423 ! radius bone intersection_of: connects UBERON:0001424 ! ulna relationship: connects UBERON:0001423 ! radius bone relationship: connects UBERON:0001424 ! ulna relationship: part_of UBERON:0002386 ! forelimb zeugopod property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/50/Forearm_labeled.png" xsd:anyURI [Term] id: UBERON:0001529 name: brachiocephalic artery namespace: uberon def: "The short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery." [MGI:csmith, MP:0010663] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "brachiocephalic trunk" EXACT [MA:0001922] synonym: "innominate" BROAD [Wikipedia:Brachiocephalic_artery] synonym: "innominate artery" EXACT [Wikipedia:Brachiocephalic_artery] synonym: "truncus brachiocephalicus" EXACT LATIN [FMA:3932, FMA:TA] synonym: "truncus brachiocephalicus" RELATED LATIN [Wikipedia:Brachiocephalic_artery] xref: EFO:0002550 xref: EHDAA2:0000835 xref: EMAPA:17615 xref: FMA:3932 xref: GAID:476 xref: galen:BrachioCephalicArtery xref: MA:0001922 xref: MESH:D016122 xref: NCIT:C32814 xref: SCTID:244244002 xref: UMLS:C0006094 {source="ncithesaurus:Innominate_Artery"} xref: Wikipedia:Brachiocephalic_artery is_a: UBERON:0004573 ! systemic artery relationship: channels_from UBERON:0001508 ! arch of aorta relationship: connected_to UBERON:0001508 ! arch of aorta relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0007204 ! brachiocephalic vasculature property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001530 name: common carotid artery plus branches namespace: uberon def: "A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]." [Wikipedia:Common_carotid_artery] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "a. carotis communis" RELATED LATIN [Wikipedia:Common_carotid_artery] synonym: "carotid artery" BROAD [FMA:3939] synonym: "carotid artery system" EXACT [EHDAA2:0000217] synonym: "common carotid artery" EXACT INCONSISTENT [FMA:3939] synonym: "trunk of common carotid tree" EXACT [FMA:3939] xref: CALOHA:TS-0116 xref: EHDAA2:0000217 xref: EHDAA:7331 xref: EMAPA:17855 xref: FMA:3939 xref: GAID:479 xref: MA:0001926 xref: MESH:D017536 xref: NCIT:C32352 xref: SCTID:362041005 xref: UMLS:C0162859 {source="ncithesaurus:Common_Carotid_Artery"} xref: VHOG:0000272 xref: Wikipedia:Common_carotid_artery is_a: UBERON:0004573 {source="FMA"} ! systemic artery relationship: connected_to UBERON:0001508 ! arch of aorta relationship: develops_from UBERON:0004363 {source="Wikipedia"} ! pharyngeal arch artery relationship: existence_starts_during UBERON:0000068 ! embryo stage relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: editor_note "we follow the FMA and treat the artery as a tree-structure - here we include the internal and external as parts. For the part that excludes the branches, see 'trunk of common carotid artery'" xsd:string property_value: IAO:0000232 "This class represents the adult and developing structures'" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000011 "in birds and reptiles, develops from arch III and parts of ventral and dorsal aortae" xsd:string [Term] id: UBERON:0001531 name: right common carotid artery plus branches namespace: uberon def: "The rightmost of the two common carotid arteries, originating from in the neck from the brachiocephalic trunk." [UBERON:cjm] subset: human_reference_atlas subset: uberon_slim synonym: "right common carotid artery" EXACT [MA:0001928] synonym: "right common carotid artery" RELATED [FMA:3941] synonym: "trunk of right common carotid tree" EXACT [FMA:3941] xref: EMAPA:35749 xref: FMA:3941 xref: MA:0001928 xref: NCIT:C33473 xref: SCTID:362042003 xref: UMLS:C0226086 {source="ncithesaurus:Right_Common_Carotid_Artery"} xref: Wikipedia:Right_common_carotid_artery is_a: UBERON:0001530 {source="FMA"} ! common carotid artery plus branches relationship: branching_part_of UBERON:0001529 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! brachiocephalic artery relationship: connected_to UBERON:0001529 ! brachiocephalic artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "placement of the MA class here is not strictly correct, as the MA class does not include the branches" xsd:string [Term] id: UBERON:0001532 name: internal carotid artery namespace: uberon def: "A terminal branch of the left or right common carotid artery which supplies oxygenated blood to the brain and eyes[MP]." [MGI:anna] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arteria carotis interna" RELATED LATIN [Wikipedia:Internal_carotid_artery] synonym: "cranial carotid artery" EXACT [ZFA:0005081] synonym: "ICA" RELATED ABBREVIATION [] synonym: "internal carotid" EXACT [AAO:0010219] xref: AAO:0010219 xref: AAO:0011054 xref: BTO:0004697 xref: EFO:0001952 xref: EHDAA2:0000873 xref: EHDAA:408 xref: EHDAA:6389 xref: EMAPA:16328 xref: FMA:3947 xref: GAID:481 xref: MA:0001930 xref: MESH:D002343 xref: NCIT:C32836 xref: SCTID:362045001 xref: TAO:0005081 xref: UMLS:C0007276 {source="ncithesaurus:Internal_Carotid_Artery"} xref: VHOG:0000267 xref: Wikipedia:Internal_carotid_artery xref: XAO:0000366 xref: ZFA:0005081 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0005396 {source="MA"} ! carotid artery segment relationship: branching_part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches relationship: develops_from UBERON:2001053 {source="cjm"} ! future internal carotid artery relationship: part_of UBERON:0001530 ! common carotid artery plus branches relationship: supplies UBERON:0000955 ! brain relationship: supplies UBERON:0000970 ! eye property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9c/Gray513.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Each of two arteries starting at the bifurcation of the common carotid arteries through which blood circulates to many structures and organs in the head. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000267", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Internal+carotid+artery"} property_value: UBPROP:0000001 "One of the major arteries of the head, it is the as the cranial continuation of the aortic arches and the dorsal aorta. It curves ventrally before resuming a dorsal course as it enters the head proper, and it lies ventral to the internal jugular vein. The internal carotid artery gives off palatine, ophthalmic, and cerebral branches by stage NF stage 41.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011054", ontology="AAO", source="PMID:12606281"} [Term] id: UBERON:0001533 name: subclavian artery namespace: uberon def: "One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: unverified_taxonomic_grouping subset: vertebrate_core synonym: "arteria subclavia" EXACT LATIN [XAO:0000365] synonym: "arteria subclavia" RELATED LATIN [Wikipedia:Subclavian_artery] synonym: "arterial tree of upper limb" EXACT [] synonym: "PA" RELATED ABBREVIATION [] synonym: "pectoral artery" EXACT [] synonym: "subclavian arterial tree" EXACT [] xref: AAO:0010232 xref: EHDAA2:0001933 xref: EHDAA:4357 xref: EMAPA:17617 xref: FMA:3951 xref: GAID:511 xref: MA:0002045 xref: MESH:D013348 xref: NCIT:C33643 xref: SCTID:265790007 xref: TAO:0005086 xref: UMLS:C0038530 {source="ncithesaurus:Subclavian_Artery"} xref: Wikipedia:Subclavian_artery xref: XAO:0000365 xref: ZFA:0005086 is_a: UBERON:0004573 ! systemic artery relationship: connected_to UBERON:0001508 ! arch of aorta relationship: develops_from UBERON:0002457 {source="EHDAA2"} ! intersomitic artery relationship: develops_from UBERON:0005622 {source="EHDAA2"} ! right dorsal aorta relationship: overlaps UBERON:0000915 ! thoracic segment of trunk relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0004710 ! pectoral appendage property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: editor_note "Developmental relationships should be added (intersegmental artery and right dorsal aorta in EHDAA2, occipitovertebral artery in XAO)" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Artery which supplies blood via branches to the various muscles of the shoulder region and to the forelimb.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010232", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "In human anatomy, the subclavian artery is a major artery of the upper thorax that mainly supplies blood to the head and arms. It is located below the clavicle, hence the name. There is a left subclavian and a right subclavian. On the left side of the body, the subclavian comes directly off the arch of aorta. On the right side of the body, the subclavian arises from the relatively short brachiocephalic artery (trunk) when it bifurcates into the subclavian and the right common carotid artery. The usual branches of the subclavian on both sides of the body are the vertebral artery, the internal thoracic artery, the thyrocervical trunk, the costocervical trunk and the dorsal scapular artery. The subclavian becomes the axillary artery at the lateral border of the first rib[WP]" xsd:string {source="Wikipedia:Subclavian_artery"} property_value: UBPROP:0000001 "The pectoral (subclavian) arteries originate from the dorsal aorta and takes the blood outward into the fin from the paired portion of the dorsal aorta posterior to the last aortic arch. Kimmel et al. 1993[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005086", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001534 name: right subclavian artery namespace: uberon def: "The subclavian artery that supplies the right pectoral appendage." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "arteria subclavia dextra" EXACT LATIN [FMA:3953, FMA:TA] xref: EHDAA2:0004514 xref: EMAPA:37384 {source="MA:th"} xref: FMA:3953 xref: MA:0002047 xref: NCIT:C33490 xref: SCTID:244246000 xref: UMLS:C0226261 {source="ncithesaurus:Right_Subclavian_Artery"} xref: Wikipedia:Subclavian_artery is_a: UBERON:0001533 ! subclavian artery is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001533 ! subclavian artery intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: branching_part_of UBERON:0001529 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! brachiocephalic artery relationship: connected_to UBERON:0001529 ! brachiocephalic artery relationship: develops_from UBERON:0003121 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="right arch 4 in human", source="embryology.ch"} ! pharyngeal arch artery 4 relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "in humans, arises from the relatively short brachiocephalic artery (trunk) when it bifurcates into the subclavian and the right common carotid artery" xsd:string property_value: UBPROP:0000011 "proximal part arises from right 4th aortic arch in humans" xsd:string [Term] id: UBERON:0001536 name: left common carotid artery plus branches namespace: uberon def: "The leftmost of the two common carotid arteries, originating from the aortic arch in the thorax." [UBERON:cjm] subset: human_reference_atlas subset: uberon_slim synonym: "left common carotid artery" EXACT [MA:0001927] synonym: "left common carotid artery" RELATED [FMA:4058] synonym: "trunk of left common carotid tree" EXACT [FMA:4058] xref: EMAPA:35491 xref: FMA:4058 xref: MA:0001927 xref: NCIT:C32956 xref: SCTID:362043008 xref: UMLS:C0226087 {source="ncithesaurus:Left_Common_Carotid_Artery"} xref: Wikipedia:Left_common_carotid_artery is_a: UBERON:0001530 {source="FMA"} ! common carotid artery plus branches property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "placement of the MA class here is not strictly correct, as the MA class does not include the branches" xsd:string [Term] id: UBERON:0001544 name: popliteal vein namespace: uberon def: "The popliteal vein course runs alongside the popliteal artery but carries the blood from the knee joint and muscles in the thigh and calf back to the heart. Its origin is defined by the junction of the posterior tibial vein and anterior tibial vein. It drains the peroneal vein before reaching the knee joint and turns into the femoral vein when leaving the adductor canal (also known as Hunter's canal). The popliteal artery extends from the femoral artery behind the popliteal fossa which is the space behind the knee. [WP,unvetted]." [Wikipedia:Popliteal_vein] subset: human_reference_atlas subset: uberon_slim synonym: "vena poplitea" RELATED LATIN [Wikipedia:Popliteal_vein] xref: EMAPA:37181 {source="MA:th"} xref: FMA:44327 xref: GAID:537 xref: galen:PoplitealVein xref: MA:0002197 xref: MESH:D011152 xref: NCIT:C33339 xref: SCTID:281065001 xref: UMLS:C0032652 {source="ncithesaurus:Popliteal_Vein"} xref: Wikipedia:Popliteal_vein is_a: UBERON:0001638 ! vein relationship: overlaps UBERON:0001465 ! knee relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0001361 {source="FMA/obol"} ! femoral vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray609.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001545 name: anterior tibial vein namespace: uberon def: "A vein of the lower limb that carries blood from the anterior compartment of the leg to the popliteal vein which is forms when it joins with the posterior tibial vein. Like most deep veins, the anterior tibial vein is accompanied by an artery of the same name, the anterior tibial artery, along its course. [WP,unvetted]." [Wikipedia:Anterior_tibial_vein] subset: human_reference_atlas subset: uberon_slim synonym: "venae tibiales anteriores" RELATED LATIN [Wikipedia:Anterior_tibial_vein] xref: EMAPA:37135 {source="MA:th"} xref: FMA:44331 xref: galen:AnteriorTibialVein xref: MA:0002244 xref: NCIT:C32115 xref: SCTID:281066000 xref: UMLS:C0226833 {source="ncithesaurus:Anterior_Tibial_Vein"} xref: Wikipedia:Anterior_tibial_vein is_a: UBERON:0010370 {source="MA"} ! tibial vein relationship: tributary_of UBERON:0001361 {source="FMA/obol"} ! femoral vein relationship: tributary_of UBERON:0001544 {source="FMA/obol"} ! popliteal vein property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/4e/Gray440_color.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001547 name: small saphenous vein namespace: uberon def: "The small saphenous vein (also lesser saphenous vein), is a relatively large vein of the superficial posterior leg. [WP,unvetted]." [Wikipedia:Small_saphenous_vein] subset: human_reference_atlas subset: uberon_slim synonym: "lesser saphenous vein" EXACT [] synonym: "short saphenous vein" EXACT [] synonym: "vena saphena parva" EXACT LATIN [Wikipedia:Small_saphenous_vein] xref: BTO:0003272 xref: EMAPA:37187 {source="MA:th"} xref: FMA:44333 xref: galen:LesserSaphenousVein xref: MA:0002217 xref: NCIT:C33546 xref: SCTID:181404009 xref: UMLS:C0226827 {source="ncithesaurus:Short_Saphenous_Vein"} xref: Wikipedia:Small_saphenous_vein is_a: UBERON:0007318 ! saphenous vein relationship: tributary_of UBERON:0001544 {source="FMA"} ! popliteal vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/62/Gray582.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001549 name: dorsal metatarsal vein namespace: uberon def: "The dorsal metatarsal veins are veins which drain the metatarsus of the foot. [WP,unvetted]." [Wikipedia:Dorsal_metatarsal_veins] subset: human_reference_atlas synonym: "metatarsal vein" EXACT [] synonym: "venae metatarsales dorsales" RELATED LATIN [Wikipedia:Dorsal_metatarsal_veins] xref: EMAPA:37143 {source="MA:th"} xref: FMA:44377 xref: MA:0002105 xref: NCIT:C52689 xref: UMLS:C0835053 {source="ncithesaurus:Dorsal_Metatarsal_Vein"} xref: Wikipedia:Dorsal_metatarsal_veins is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0000983 ! metatarsus region relationship: drains UBERON:0000983 ! metatarsus region relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0008783 ! dorsal venous arch property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001550 name: medial marginal vein namespace: uberon def: "A continuation of the Dorsal venous arch of the foot and is the origin of the long saphenous vein." [Wikipedia:Medial_marginal_vein] subset: human_reference_atlas synonym: "medial marginal vein of foot" EXACT [] synonym: "vena marginalis medialis" EXACT [] synonym: "vena marginalis medialis pedis" EXACT LATIN [FMA:44420, FMA:TA] xref: EMAPA:37170 {source="MA:th"} xref: FMA:44420 xref: MA:0002171 xref: Wikipedia:Medial_marginal_vein is_a: UBERON:0001638 ! vein relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0001363 {source="FMA/obol"} ! great saphenous vein property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001554 name: skin of hip namespace: uberon def: "A zone of skin that is part of a hip region." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "hip region zone of skin" EXACT [OBOL:automatic] synonym: "hip skin" EXACT [] synonym: "hip zone of skin" EXACT [OBOL:automatic] synonym: "regio coxae zone of skin" EXACT [OBOL:automatic] synonym: "zone of skin of hip" EXACT [OBOL:automatic] synonym: "zone of skin of hip region" EXACT [OBOL:automatic] synonym: "zone of skin of regio coxae" EXACT [OBOL:automatic] xref: EMAPA:18148 xref: FMA:45282 xref: MA:0000658 xref: SCTID:181518004 is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001464 ! hip relationship: part_of UBERON:0001464 ! hip property_value: UBPROP:0000012 "in MA this isa hindlimb skin" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001555 name: digestive tract namespace: uberon def: "A tube extending from the mouth to the anus." [https://github.com/geneontology/go-ontology/issues/7549, Wikipedia:Talk\:Human_gastrointestinal_tract] subset: uberon_slim subset: vertebrate_core synonym: "alimentary canal" NARROW [] synonym: "alimentary tract" NARROW [] synonym: "digestive canal" RELATED [BTO:0000058] synonym: "digestive tube" EXACT [] synonym: "enteric tract" EXACT [ZFA:0000112] synonym: "gut" BROAD [] synonym: "gut tube" RELATED [] xref: AAO:0010023 xref: BILA:0000083 xref: BTO:0000511 xref: BTO:0000545 xref: EHDAA2:0000726 xref: EHDAA:518 xref: EMAPA:16247 xref: FBbt:00003125 xref: FMA:45615 xref: galen:AlimentaryTract xref: MA:0000917 xref: NCIT:C34082 xref: TAO:0000112 xref: TGMA:0001819 xref: UMLS:C0017189 {source="ncithesaurus:Gastrointestinal_Tract"} xref: VHOG:0000309 xref: WBbt:0005743 xref: ZFA:0000112 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000025 ! tube relationship: connects UBERON:0000165 ! mouth relationship: develops_from UBERON:0007026 ! presumptive gut relationship: immediate_transformation_of UBERON:0007026 {source="NCBIBook:NBK10107"} ! presumptive gut relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001007 ! digestive system property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: RO:0002161 NCBITaxon:41324 {source="DOI:10.1371/journal.pone.0016309"} property_value: UBPROP:0000001 "The alimentary or digestive tract, and associated organs.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000112", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The bilaterian gut is typically a complete tube that opens to the exterior at both ends. It consists of mouth, foregut, midgut, hindgut, and anus (reference 1); Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000309", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.203, ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "FMA also has a term 'gastrointestinal tract', but this includes the liver." xsd:string {external_ontology="FMA"} property_value: UBPROP:0000012 "we place the MA and EMAPA class here, although the intent is probably a smaller region. See https://github.com/obophenotype/uberon/issues/509" xsd:string {external_ontology="MA"} property_value: UBPROP:0000013 "we following Kardong in naming the entire tube from mouth to anus the alimentary canal. Kardong calls the portion of this tract that excludes buccal cavity and pharynx the 'alimentary canal', consider adding an extra class for this" xsd:string [Term] id: UBERON:0001556 name: lower urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the urinary bladder and the urethra." [FMA:45659] subset: pheno_slim subset: uberon_slim xref: FMA:45659 xref: galen:LowerUrinaryTract xref: MA:0002636 xref: SCTID:181420004 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 ! organ system subdivision relationship: has_part UBERON:0000057 ! urethra relationship: has_part UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001008 ! renal system [Term] id: UBERON:0001557 name: upper respiratory tract namespace: uberon def: "The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim xref: EHDAA2:0002136 xref: EMAPA:17669 xref: FMA:45661 xref: MA:0000442 xref: SCTID:361381009 xref: VHOG:0000406 xref: Wikipedia:Upper_respiratory_tract is_a: UBERON:0000072 ! proximo-distal subdivision of respiratory tract is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: has_part UBERON:0000004 ! nose property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_conducting_passages.jpg" xsd:anyURI property_value: RO:0002171 UBERON:0001558 property_value: UBPROP:0000012 "Some specify that the glottis (vocal cords) is the defining line between the upper and lower respiratory tracts;[2] yet even others make the line at the cricoid cartilage. The FMA includes nose, nasopharynx, oropharynx and larynx[WP]" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001558 name: lower respiratory tract namespace: uberon def: "The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Lower_respiratory_tract] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "lower respiratory system" EXACT [] xref: EHDAA2:0001036 xref: EMAPA:16738 xref: FMA:45662 xref: MA:0000435 xref: SCTID:281488008 xref: VHOG:0000382 xref: Wikipedia:Lower_respiratory_tract is_a: UBERON:0000072 ! proximo-distal subdivision of respiratory tract relationship: has_part UBERON:0000170 ! pair of lungs property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_conducting_passages.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001560 name: neck of organ namespace: uberon subset: non_informative synonym: "organ neck" EXACT [] xref: FMA:45733 is_a: UBERON:0034944 {source="FMA"} ! zone of organ relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa [Term] id: UBERON:0001568 name: muscle of larynx namespace: uberon def: "The muscles associated with the larynx." [MP:0002263] subset: human_reference_atlas subset: pheno_slim synonym: "laryngeal muscle" EXACT [] synonym: "larynx muscle" EXACT [] synonym: "larynx muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of larynx" EXACT [OBOL:automatic] synonym: "musculi laryngeales" EXACT [] xref: BTO:0001626 xref: EMAPA:35473 xref: FMA:46562 xref: GAID:144 xref: MA:0001768 xref: MESH:D007821 xref: NCIT:C32934 xref: SCTID:181744001 xref: UMLS:C0023054 {source="ncithesaurus:Laryngeal_Muscle"} xref: Wikipedia:Muscles_of_larynx is_a: UBERON:0002377 ! muscle of neck is_a: UBERON:0003831 ! respiratory system muscle is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0001737 ! larynx relationship: contributes_to_morphology_of UBERON:0001015 ! musculature relationship: contributes_to_morphology_of UBERON:0001737 ! larynx relationship: part_of UBERON:0004478 {source="prolog"} ! musculature of larynx property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001571 name: genioglossus muscle namespace: uberon def: "Either of a pair of lingual muscles with origin in the mandible, with insertion to the lingual fascia below the mucous membrane and epiglottis, with nerve supply from the hypoglossal nerve, and whose action depresses and protrudes the tongue." [VHOG:0000847, Wikipedia:Genioglossus_muscle] subset: human_reference_atlas subset: uberon_slim synonym: "genioglossus" EXACT [] synonym: "m. genioglossus" EXACT [] synonym: "musculus genioglossus" EXACT [] xref: AAO:0010660 xref: EHDAA2:0000704 xref: EHDAA:9150 xref: EMAPA:18276 xref: FMA:46690 xref: MA:0002307 xref: NCIT:C52928 xref: SCTID:244784007 xref: UMLS:C0224194 {source="ncithesaurus:Genioglossus"} xref: VHOG:0000847 xref: Wikipedia:Genioglossus_muscle is_a: UBERON:0001575 {source="FMA"} ! extrinsic muscle of tongue is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from UBERON:0010059 {source="EHDAA2"} ! hypoglossal cord relationship: has_muscle_insertion UBERON:0009471 {source="Wikipedia"} ! dorsum of tongue relationship: has_muscle_origin UBERON:0006606 ! mandibular symphysis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7e/Genioglossus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Either of a pair of lingual muscles with origin in the mandible, with insertion to the lingual fascia below the mucous membrane and epiglottis, with nerve supply from the hypoglossal nerve, and whose action depresses and protrudes the tongue. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000847", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/genioglossus"} property_value: UBPROP:0000001 "Makes up bulk of tongue in frogs and salamanders; makes up entire tongue in caecilians.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010660", ontology="AAO", source="AAO:BMZ"} property_value: UBPROP:0000001 "see Intrinsic Tongue.[FEED]" xsd:string {date_retrieved="2012-07-02", ontology="FEED", url="http://www.feedexp.org"} property_value: UBPROP:0000002 "relationship loss: subclass hyobranchial muscles (AAO:0000224)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010660", ontology="AAO"} property_value: UBPROP:0000003 "The lamprey head contains another group of muscles, the epi- and hypo-branchial muscles (EBM and HBM), derivatives of anterior trunk myotomes. (...) The origin and the migration pattern of HBM precursors are very similar to that of the gnathostome MPP, especially to that of the tongue muscle precursors. Other evidence of homology of lamprey HBM to the gnathostome tongue muscle is that HBM is innervated by the nerve termed the hypoglossal nerve based on its morphological position associated with the head/trunk interface. (...) The HBM-specific expression of the LampPax3/7 gene is consistent with the homology of this muscle to the gnathostome tongue muscle, or to the hypobranchial series as a whole (including the infrahyoid and possibly the diaphragm in mammals).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000847", ontology="VHOG", source="DOI:10.1002/dvdy.20587, DOI:10.1186/1471-213X-8-24 Table 7", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Makes up bulk of tongue in frogs and salamanders; makes up entire tongue in caecilians." xsd:string {source="AAO:0010660"} [Term] id: UBERON:0001572 name: hyoglossus muscle namespace: uberon def: "A muscle that attaches to the hyopid bone and to the tongue and is innervated by cranial nerve XII." [FEED:rd] subset: human_reference_atlas subset: uberon_slim synonym: "hyoglossus" EXACT [Wikipedia:Hyoglossus] synonym: "m. hyoglossus" EXACT [] xref: AAO:0010663 xref: EMAPA:18277 xref: FMA:46691 xref: MA:0002317 xref: MFMO:0000064 xref: NCIT:C53161 xref: SCTID:244785008 xref: UMLS:C0224196 {source="ncithesaurus:Hyoglossus_Muscle"} xref: Wikipedia:Hyoglossus_muscle is_a: UBERON:0001575 {source="FMA"} ! extrinsic muscle of tongue intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0001685 ! hyoid bone intersection_of: attaches_to UBERON:0001723 ! tongue intersection_of: innervated_by UBERON:0001650 ! hypoglossal nerve relationship: attaches_to UBERON:0001685 ! hyoid bone relationship: attaches_to UBERON:0001723 ! tongue relationship: has_muscle_insertion UBERON:0001723 ! tongue relationship: has_muscle_origin UBERON:0001685 {notes="lingual process in horse", source="dbpedia"} ! hyoid bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7e/Hyoglossus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Makes up part of the tongue in frogs and salamanders.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010663", ontology="AAO", source="AAO:BMZ"} property_value: UBPROP:0000001 "The hyoglossus is a muscle that attaches to the hyoid and tongue and is innervated by Cranial Nerve XII.[FEED]" xsd:string {date_retrieved="2012-07-02", ontology="FEED", url="http://www.feedexp.org"} property_value: UBPROP:0000002 "relationship loss: subclass hyobranchial muscles (AAO:0000224)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010663", ontology="AAO"} [Term] id: UBERON:0001575 name: extrinsic muscle of tongue namespace: uberon def: "A muscle organ that attaches the tongue to some other structure." [https://github.com/obophenotype/uberon/issues/331, Wikipedia:Muscles_of_tongue] subset: human_reference_atlas synonym: "extrinsic lingual muscle" EXACT [] synonym: "extrinsic tongue muscle" EXACT [] xref: EHDAA2:0002063 xref: EHDAA:9148 xref: EMAPA:18275 xref: FMA:46699 xref: MA:0002296 xref: SCTID:244782006 xref: VHOG:0000825 is_a: UBERON:0000378 {is_inferred="true"} ! tongue muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0004765 ! skeletal element intersection_of: attaches_to_part_of UBERON:0001723 ! tongue intersection_of: innervated_by UBERON:0001650 ! hypoglossal nerve relationship: attaches_to UBERON:0004765 ! skeletal element relationship: develops_from UBERON:0011332 ! extrinsic tongue pre-muscle mass relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/dosumis relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/RDruzinsky relationship: immediate_transformation_of UBERON:0011332 ! extrinsic tongue pre-muscle mass relationship: innervated_by UBERON:0001650 {notes="check palatoglossus", source="Wikipedia"} ! hypoglossal nerve property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "The lamprey head contains another group of muscles, the epi- and hypo-branchial muscles (EBM and HBM), derivatives of anterior trunk myotomes. (...) The origin and the migration pattern of HBM precursors are very similar to that of the gnathostome MPP, especially to that of the tongue muscle precursors. Other evidence of homology of lamprey HBM to the gnathostome tongue muscle is that HBM is innervated by the nerve termed the hypoglossal nerve based on its morphological position associated with the head/trunk interface. (...) The HBM-specific expression of the LampPax3/7 gene is consistent with the homology of this muscle to the gnathostome tongue muscle, or to the hypobranchial series as a whole (including the infrahyoid and possibly the diaphragm in mammals).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000825", ontology="VHOG", source="DOI:10.1002/dvdy.20587 Kusakabe R, Kuratani S, Evolution and developmental patterning of the vertebrate skeletal muscles: perspectives from the lamprey. Developmental Dynamics (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000009 "main functions are altering the tongue's position allowing for protrusion, retraction, and side-to-side movement" xsd:string {source="WP"} property_value: UBPROP:0000010 "All intrinsic and extrinsic muscles of the tongue are supplied by the hypoglossal nerve (CN XII), except for one of the extrinsic muscles, palatoglossus, which is innervated by the Vagus nerve CN X of the pharyngeal plexus." xsd:string {source="WP"} [Term] id: UBERON:0001576 name: intrinsic muscle of tongue namespace: uberon def: "The intrinsic tongue muscles are an integral part of the tongue and completely contained within the tongue that are innervated by Cranial Nerve XII." [http://www.feedexp.org/wiki/Mammalian_Muscle_Ontology_Workshop] subset: human_reference_atlas synonym: "intrinsic lingual muscle" EXACT [] synonym: "intrinsic tongue muscle" EXACT [] xref: EHDAA2:0002064 xref: EHDAA:9152 xref: EMAPA:18280 xref: FMA:46701 xref: MA:0002327 xref: SCTID:244788005 xref: VHOG:0000748 is_a: UBERON:0000378 {is_inferred="true"} ! tongue muscle is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to_part_of UBERON:0001723 ! tongue intersection_of: innervated_by UBERON:0001650 ! hypoglossal nerve intersection_of: part_of UBERON:0001723 ! tongue relationship: develops_from UBERON:0010059 {source="EHDAA2"} ! hypoglossal cord relationship: innervated_by UBERON:0001650 {source="FEED", source="Wikipedia"} ! hypoglossal nerve relationship: part_of UBERON:0001723 ! tongue property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The intrinsic tongue muscles are an integral part of the tongue that are innervated by Cranial Nerve XII.[FEED]" xsd:string {date_retrieved="2012-07-02", ontology="FEED", url="http://www.feedexp.org"} property_value: UBPROP:0000003 "The lamprey head contains another group of muscles, the epi- and hypo-branchial muscles (EBM and HBM), derivatives of anterior trunk myotomes. (...) The origin and the migration pattern of HBM precursors are very similar to that of the gnathostome MPP, especially to that of the tongue muscle precursors. Other evidence of homology of lamprey HBM to the gnathostome tongue muscle is that HBM is innervated by the nerve termed the hypoglossal nerve based on its morphological position associated with the head/trunk interface. (...) The HBM-specific expression of the LampPax3/7 gene is consistent with the homology of this muscle to the gnathostome tongue muscle, or to the hypobranchial series as a whole (including the infrahyoid and possibly the diaphragm in mammals).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000748", ontology="VHOG", source="DOI:10.1002/dvdy.20587 Kusakabe R, Kuratani S, Evolution and developmental patterning of the vertebrate skeletal muscles: perspectives from the lamprey. Developmental Dynamics (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000009 "The main function of the intrinsic muscles is to provide shape. They are not involved with changing the position of the tongue and are not attached to bone" xsd:string {source="WP"} [Term] id: UBERON:0001577 name: facial muscle namespace: uberon def: "A muscle innervated by a facial nerve." [FEED:rd] subset: pheno_slim subset: uberon_slim synonym: "cranial-facial muscle" RELATED [EMAPA:25133] synonym: "cranio-facial muscle" RELATED [EMAPA:25133] synonym: "craniofacial muscle" RELATED [EMAPA:25133] synonym: "face muscle" EXACT [FMA:46751] synonym: "face muscle organ" EXACT [OBOL:automatic] synonym: "facial muscle" EXACT [FMA:46751, XAO:0001013] synonym: "facial muscle proper" EXACT [] synonym: "facial nerve innervated muscle" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "facial nerve muscle" EXACT [] synonym: "mimetic muscles" RELATED [Wikipedia:Facial_muscles] synonym: "muscle of face" EXACT [FMA:46751] synonym: "muscle of facil expression" RELATED [Wikipedia:Facial_muscles] synonym: "muscle organ of face" EXACT [OBOL:automatic] synonym: "muscles of facial expression" RELATED [Wikipedia:Facial_muscles] synonym: "musculi faciei" RELATED LATIN [Wikipedia:Facial_muscles] xref: FMA:46751 xref: GAID:143 xref: MA:0003160 xref: MESH:D005152 xref: MFMO:0000005 xref: NCIT:C13073 xref: SCTID:25903009 xref: UMLS:C0015460 {source="ncithesaurus:Facial_Muscle"} xref: Wikipedia:Facial_muscles xref: XAO:0001013 is_a: UBERON:0015789 ! cranial or facial muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: innervated_by UBERON:0001647 ! facial nerve relationship: develops_from UBERON:0003066 {source="FEED", source="Wikipedia"} ! pharyngeal arch 2 relationship: innervated_by UBERON:0001647 ! facial nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray378.png" xsd:anyURI [Term] id: UBERON:0001584 name: left subclavian artery namespace: uberon def: "The subclavian artery that supplies the left pectoral appendage." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "arteria subclavia (sinistra)" EXACT LATIN [FMA:4694, FMA:TA] xref: EMAPA:37100 {source="MA:th"} xref: FMA:4694 xref: MA:0002046 xref: NCIT:C32972 xref: SCTID:244245001 xref: UMLS:C0226262 {source="ncithesaurus:Left_Subclavian_Artery"} xref: Wikipedia:Subclavian_artery is_a: UBERON:0001533 ! subclavian artery is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001533 ! subclavian artery intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: channels_from UBERON:0001508 ! arch of aorta relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e6/Gray506.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "in humans, branches off the arch of aorta" xsd:string property_value: UBPROP:0000011 "arises from left intersegmental 6th artery in the region of the 6th -7th cervical segment in humans" xsd:string [Term] id: UBERON:0001585 name: anterior vena cava namespace: uberon def: "A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Superior_vena_cava] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "cranial vena cava" RELATED [VHOG:0001195] synonym: "precava" RELATED [] synonym: "superior caval vein" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "superior vena cava" EXACT [FMA:4720] synonym: "vena cava superior" RELATED LATIN [BTO:0002683, Wikipedia:Superior_vena_cava] synonym: "vena maxima" RELATED LATIN [Wikipedia:Superior_vena_cava] xref: BTO:0002683 xref: EHDAA2:0001962 xref: EHDAA:8726 xref: EMAPA:18417 xref: FMA:4720 xref: GAID:549 xref: galen:SuperiorVenaCava xref: MA:0000481 xref: MESH:D014683 xref: NCIT:C12816 xref: SCTID:181368006 xref: UMLS:C0042459 {source="ncithesaurus:Superior_Vena_Cava"} xref: VHOG:0001195 xref: Wikipedia:Superior_vena_cava is_a: UBERON:0004087 ! vena cava intersection_of: UBERON:0004087 ! vena cava intersection_of: drains UBERON:0000153 ! anterior region of body relationship: connected_to UBERON:0002078 ! right cardiac atrium relationship: drains UBERON:0000153 ! anterior region of body relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b4/Venenwinkel.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Phylogenetic modifications within this basic pattern of arteries and veins are largely correlated with functional changes. In the transition from water to land, gills gave way to lungs, accompanied by the establishment of a pulmonary circulation. In some fishes and certainly in tetrapods, the cardinal veins become less involved in blood return. Instead, the composite, prominent postcava (posterior vena cava) arose to drain the posterior part of the body and the precava (anterior vena cava) developed to drain the anterior part of the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001195", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.454-455", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "The mouse has both left and right anterior vena cava. adult humans only have a right. Postnatally the left regresses and becomes non-functional (Wessels and Sedmera 2003). In the mouse, The right pulmonary vein passes dorsal to the right superior vena cava, the left pulmonary dorsal to the left superior vena cava (Biology of the Laboratory Mouse, Green)." xsd:string [Term] id: UBERON:0001586 name: internal jugular vein namespace: uberon def: "One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]." [Wikipedia:Internal_jugular_vein] subset: human_reference_atlas subset: uberon_slim synonym: "internal jugular" EXACT [EHDAA2:0000877] synonym: "internal jugular venous tree" EXACT [] synonym: "vena jugularis interna" RELATED LATIN [Wikipedia:Internal_jugular_vein] xref: AAO:0010236 xref: EHDAA2:0000877 xref: EHDAA:5407 xref: EMAPA:17620 xref: FMA:4724 xref: galen:InternalJugularVein xref: MA:0002157 xref: NCIT:C32849 xref: RETIRED_EHDAA2:0000878 xref: SCTID:181372005 xref: UMLS:C0226550 {source="ncithesaurus:Internal_Jugular_Vein"} xref: Wikipedia:Internal_jugular_vein xref: XAO:0000382 is_a: UBERON:0004711 ! jugular vein relationship: connected_to UBERON:0003711 ! brachiocephalic vein relationship: drains UBERON:0000955 ! brain relationship: drains UBERON:0001456 ! face property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e9/Gray562.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Vein which receives many veins draining the palate, brain, and the orbital, nasal, and auditory regions.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010236", ontology="AAO", source="AAO:BJB"} [Term] id: UBERON:0001587 name: subclavian vein namespace: uberon def: "The subclavian vein is a paired large vein, one on either side of the body. Their diameter is approximately that of the smallest finger." [Wikipedia:Subclavian_vein] subset: human_reference_atlas subset: uberon_slim synonym: "subclavian venous tree" EXACT [] synonym: "vena subclavia" EXACT LATIN [Wikipedia:Subclavian_vein] xref: AAO:0010510 xref: EHDAA2:0001934 xref: EHDAA:4455 xref: EMAPA:17621 xref: FMA:4725 xref: GAID:546 xref: galen:SubclavianVein xref: MA:0002221 xref: MESH:D013350 xref: NCIT:C12794 xref: SCTID:181388005 xref: UMLS:C0038532 {source="ncithesaurus:Subclavian_Vein"} xref: Wikipedia:Subclavian_vein is_a: UBERON:0001638 ! vein relationship: connected_to UBERON:0003711 ! brachiocephalic vein relationship: drains UBERON:0004710 ! pectoral appendage relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray1174.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Vein which collects blood from the forelimb via the brachial veins and from the muscles and skin of the trunk via the anterior epigastric and lateral veins.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010510", ontology="AAO", source="AAO:BJB"} [Term] id: UBERON:0001592 name: bronchial vein namespace: uberon def: "The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted]." [Wikipedia:Bronchial_veins] subset: human_reference_atlas subset: uberon_slim synonym: "bronchial venous tree" EXACT [] xref: EMAPA:36284 xref: FMA:4749 xref: MA:0002088 xref: NCIT:C53031 xref: SCTID:198293000 xref: UMLS:C0226650 {source="ncithesaurus:Bronchial_Vein"} xref: Wikipedia:Bronchial_veins is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002185 ! bronchus relationship: drains UBERON:0002185 ! bronchus relationship: part_of RO:0002577 ! system property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001593 name: venous plexus namespace: uberon def: "A congregation of multiple veins." [Wikipedia:Venous_plexus] subset: uberon_slim synonym: "plexus venosus" RELATED LATIN [Wikipedia:Venous_plexus] synonym: "rete venosum" RELATED LATIN [Wikipedia:Venous_plexus] synonym: "venous network" EXACT [] xref: EMAPA:36327 xref: FMA:4767 xref: MA:0000069 xref: SCTID:322151008 xref: Wikipedia:Venous_plexus is_a: UBERON:0004537 ! blood vasculature is_a: UBERON:0005629 ! vascular plexus intersection_of: UBERON:0005629 ! vascular plexus intersection_of: composed_primarily_of UBERON:0001638 ! vein relationship: composed_primarily_of UBERON:0001638 ! vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png" xsd:anyURI [Term] id: UBERON:0001605 name: ciliary muscle namespace: uberon def: "The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]." [Wikipedia:Ciliary_muscle] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "Bowman`s muscles" RELATED [BTO:0000654] synonym: "ciliaris" RELATED [Wikipedia:Ciliary_muscle] synonym: "musculus ciliaris" RELATED LATIN [Wikipedia:Ciliary_muscle] synonym: "musculus ciliarus" EXACT [BTO:0000654] xref: BTO:0000654 xref: EMAPA:35240 xref: FMA:49151 xref: MA:0001269 xref: NCIT:C32315 xref: SCTID:280862009 xref: UMLS:C0559230 {source="ncithesaurus:Ciliary_Muscle"} xref: Wikipedia:Ciliary_muscle is_a: UBERON:0003386 {source="MA"} ! smooth muscle of eye is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0011222 {source="FMA"} ! intra-ocular muscle relationship: part_of UBERON:0001775 {source="FMA"} ! ciliary body property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray872.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001606 name: muscle of iris namespace: uberon def: "." [Wikipedia:Iris_muscle] subset: uberon_slim synonym: "iris muscle" EXACT [] synonym: "iris muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of iris" EXACT [OBOL:automatic] xref: EMAPA:35448 xref: FMA:49154 xref: MA:0001287 xref: SCTID:280888007 xref: Wikipedia:Iris_muscle is_a: UBERON:0011222 {source="FMA"} ! intra-ocular muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001769 ! iris relationship: part_of UBERON:0001769 ! iris property_value: editor_note "revisit this, see issue #331" xsd:string property_value: UBPROP:0000008 "in aves, stromal mesenchymal cells may migrate to the iris and become skeletal" xsd:string property_value: UBPROP:0000008 "The muscle cells of the iris are smooth muscle in mammals and amphibians, but are striated muscle in birds and reptiles. Many fish have neither, and, as a result, their irides are unable to dilate and contract, so that the pupil always remains of a fixed size[Romer, via WP]" xsd:string [Term] id: UBERON:0001607 name: sphincter pupillae namespace: uberon def: "A sphincter muscle that is part of the iris." [Wikipedia:Iris_sphincter_muscle] subset: uberon_slim synonym: "circular fibers" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "constrictor pupillae" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "iris constrictor" RELATED [] synonym: "iris constrictor muscle" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "iris sphincter" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "iris sphincter muscle" EXACT [BTO:0000656] synonym: "M. sphincter pupillae" EXACT [] synonym: "m. sphincter pupillae" RELATED LATIN [Wikipedia:Iris_sphincter_muscle] synonym: "musculus sphincter pupillae" EXACT [BTO:0000656] synonym: "pupillary constrictor muscle" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "pupillary sphincter" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "pupillary sphincter muscle" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "sphincter muscle of pupil" EXACT [BTO:0000656] synonym: "sphincter pupillae" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "sphincter pupillae muscle" RELATED [Wikipedia:Iris_sphincter_muscle] synonym: "spincter pupillae" RELATED [Wikipedia:Iris_sphincter_muscle] xref: BTO:0000656 xref: EMAPA:35788 xref: FMA:49157 xref: MA:0001289 xref: NCIT:C33586 xref: SCTID:280889004 xref: UMLS:C0229189 {source="ncithesaurus:Sphincter_Pupillae_Muscle"} xref: Wikipedia:Iris_sphincter_muscle is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001606 ! muscle of iris is_a: UBERON:0004234 {source="BTO"} ! iris smooth muscle is_a: UBERON:0007521 ! smooth muscle sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0001769 ! iris relationship: develops_from UBERON:0002346 {source="ISBN:0781772214"} ! neurectoderm relationship: has_muscle_antagonist UBERON:0001608 {source="dbpedia"} ! dilatator pupillae relationship: has_muscle_insertion UBERON:0001769 {notes="encircles iris", source="dbpedia"} ! iris relationship: has_muscle_origin UBERON:0001769 {notes="encircles iris", source="dbpedia"} ! iris relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png" xsd:anyURI property_value: UBPROP:0000008 "In humans, it functions to constrict the pupil in bright light or during accommodation. Its dimensions are about 0.75 mm wide by 0.15 mm thick. It is controlled by parasympathetic fibers that originate from the Edinger-Westphal nucleus, travel along the oculomotor nerve (CN III), synapse in the ciliary ganglion, and then enter the eye via the short ciliary nerves. Initially, all the myocytes are of the smooth muscle type, but much later in life, so that ultimately most cells are of the striated muscle type. [WP,unvetted]" xsd:string property_value: UBPROP:0000008 "WP says: It is found in vertebrates and some cephalopods; this class refers to the vertebrate structure" xsd:string property_value: UBPROP:0000009 "constricts iris" xsd:string [Term] id: UBERON:0001608 name: dilatator pupillae namespace: uberon def: "A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]." [Wikipedia:Iris_dilator_muscle] subset: human_reference_atlas subset: uberon_slim synonym: "dilator muscle of pupil" EXACT [] synonym: "dilator of pupil" EXACT [] synonym: "dilator pupillae" EXACT [] synonym: "dilator pupillae muscle" EXACT [Wikipedia:Iris_dilator_muscle] synonym: "dilator pupillae muscle" RELATED [BTO:0001371] synonym: "iris dilator" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "iris dilator muscle" EXACT [BTO:0001371] synonym: "musculus dilatator pupillae" EXACT LATIN [FMA:49158, FMA:TA] synonym: "musculus dilatator pupillae" RELATED LATIN [Wikipedia:Iris_dilator_muscle] synonym: "musculus dilator pupillae" RELATED [BTO:0001371] synonym: "pupil dilator" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "pupil dilator muscle" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "pupillary dilator" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "pupillary dilator muscle" EXACT [Wikipedia:Iris_dilator_muscle] synonym: "pupillary muscle" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "radial muscle" RELATED [Wikipedia:Iris_dilator_muscle] synonym: "radial muscle of iris" EXACT [Wikipedia:Iris_dilator_muscle] synonym: "radiating fibers" RELATED [Wikipedia:Iris_dilator_muscle] xref: BTO:0001371 xref: EMAPA:35286 xref: FMA:49158 xref: MA:0001288 xref: NCIT:C32463 xref: SCTID:280890008 xref: UMLS:C0229190 {source="ncithesaurus:Dilator_Pupillae_Muscle"} xref: Wikipedia:Iris_dilator_muscle is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004234 {source="BTO"} ! iris smooth muscle relationship: develops_from UBERON:0002346 {source="ISBN:0781772214"} ! neurectoderm relationship: has_muscle_antagonist UBERON:0001607 {source="dbpedia"} ! sphincter pupillae relationship: has_muscle_insertion UBERON:0001769 {notes="inner margins of iris", source="dbpedia"} ! iris relationship: has_muscle_origin UBERON:0001769 {notes="outer margins of iris", source="dbpedia"} ! iris relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray878.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000009 "It is innervated by the sympathetic system, which acts by releasing noradrenaline, which acts on alpha1-receptors. Thus, when presented with a threatening stimuli that activates the fight-or-flight response, this innervation dilates the iris, thus temporarily letting more light reach the retina" xsd:string [Term] id: UBERON:0001610 name: lingual artery namespace: uberon def: "The lingual artery arises from the external carotid between the superior thyroid and facial artery[WP]." [Wikipedia:Lingual_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria lingualis" RELATED LATIN [Wikipedia:Lingual_artery] synonym: "lingual branch of external carotid artery" EXACT [] xref: AAO:0010492 xref: EMAPA:36324 xref: FMA:49526 xref: MA:0001992 xref: NCIT:C52961 xref: SCTID:181327002 xref: UMLS:C0226104 {source="ncithesaurus:Lingual_Artery"} xref: Wikipedia:Lingual_artery is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0035398 ! branch of external carotid artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001723 ! tongue relationship: in_lateral_side_of UBERON:0001723 {source="FMA-abduced-lr"} ! tongue relationship: part_of UBERON:0001723 ! tongue relationship: supplies UBERON:0001723 ! tongue property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/3c/Lingual_artery.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the external carotid which supplies blood to the tongue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010492", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship loss: part_of external carotid (AAO:0010218)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010492", ontology="AAO"} [Term] id: UBERON:0001612 name: facial artery namespace: uberon def: "A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]." [Wikipedia:Facial_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria maxillaris externa" RELATED LATIN [Wikipedia:Facial_artery] synonym: "external maxillary artery" RELATED [] xref: EMAPA:19213 xref: FMA:49549 xref: MA:0001950 xref: NCIT:C32578 xref: SCTID:181328007 xref: UMLS:C0226109 {source="ncithesaurus:Facial_Artery"} xref: Wikipedia:Facial_artery is_a: UBERON:0035398 ! branch of external carotid artery intersection_of: UBERON:0001637 ! artery intersection_of: branching_part_of UBERON:0001070 ! external carotid artery intersection_of: supplies UBERON:0001456 ! face relationship: supplies UBERON:0001456 ! face property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7b/Gray508.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001616 name: maxillary artery namespace: uberon def: "An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]." [Wikipedia:Maxillary_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria maxillaris" RELATED LATIN [Wikipedia:Maxillary_artery] synonym: "internal maxillary artery" RELATED [] xref: EHDAA2:0001069 xref: EHDAA:7357 xref: EMAPA:17311 xref: FMA:49675 xref: GAID:498 xref: MA:0001919 xref: MESH:D008438 xref: NCIT:C34205 xref: SCTID:181326006 xref: UMLS:C0024949 {source="ncithesaurus:Maxillary_Artery"} xref: Wikipedia:Maxillary_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: directly_develops_from UBERON:0003118 ! pharyngeal arch artery 1 relationship: connected_to UBERON:0001070 ! external carotid artery relationship: develops_from UBERON:0003118 ! pharyngeal arch artery 1 relationship: directly_develops_from UBERON:0003118 ! pharyngeal arch artery 1 relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/39/Gray510.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000011 "...1st pair undergoes partial regression, the remnants of which becomes part of the maxillary arteries" xsd:string {source="http://download.videohelp.com/vitualis/med/Vascular_Devt.html"} [Term] id: UBERON:0001628 name: posterior communicating artery namespace: uberon def: "One of a pair of right-sided and left-sided blood vessels in the circle of Willis. It connects the three cerebral arteries of the same side. Anteriorly, it is one portion of the terminal trifurcation of the internal carotid artery. The anterior cerebral artery and the middle cerebral artery are the other two branches of the trifurcation. Posteriorly, it communicates with the posterior cerebral artery." [Wikipedia:Posterior_communicating_artery] subset: human_reference_atlas subset: uberon_slim subset: vertebrate_core synonym: "arteria cerebri communicans posterior" RELATED LATIN [Wikipedia:Posterior_communicating_artery] synonym: "caudal communicating segment" EXACT [ZFA:0005001] synonym: "PCA" RELATED [] synonym: "PCS" RELATED [] synonym: "posterior communicating segment of the basilar artery" EXACT [ZFA:0005001] xref: EHDAA2:0004518 xref: EHDAA:3352 xref: EMAPA:18600 xref: FMA:50084 xref: MA:0002023 xref: NCIT:C33357 xref: RETIRED_EHDAA2:0001487 xref: SCTID:181314001 xref: TAO:0005001 xref: UMLS:C0149559 {source="ncithesaurus:Posterior_Communicating_Artery"} xref: Wikipedia:Posterior_communicating_artery xref: ZFA:0005001 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0004573 ! systemic artery is_a: UBERON:0006347 ! communicating artery is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0006347 ! communicating artery intersection_of: branching_part_of UBERON:0001532 ! internal carotid artery intersection_of: part_of UBERON:0003709 ! circle of Willis relationship: branching_part_of UBERON:0001532 {source="FMA", source="ZFA"} ! internal carotid artery relationship: in_lateral_side_of UBERON:0003709 {source="FMA-abduced-lr"} ! circle of Willis relationship: part_of UBERON:0001532 ! internal carotid artery relationship: part_of UBERON:0003709 ! circle of Willis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2e/Circle_of_Willis_en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "An artery that connects caudal division of the internal carotid artery and the basal communicating artery to the basilar artery. Isogai et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005001", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000008 "todo - verify ZFA link: An artery that connects caudal division of the internal carotid artery and the basal communicating artery to the basilar artery" xsd:string [Term] id: UBERON:0001630 name: muscle organ namespace: uberon def: "Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]." [GO:0007517] subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "muscle" BROAD [ZFA:0005145] xref: AAO:0011066 xref: EMAPA:32715 xref: EMAPA:37474 {source="MA:th"} xref: EV:0100146 xref: FMA:5022 xref: GAID:131 xref: galen:Muscle xref: MA:0000015 xref: SCTID:71616004 xref: TAO:0005145 xref: VHOG:0001245 xref: XAO:0000172 xref: ZFA:0005145 is_a: UBERON:0000062 ! organ is_a: UBERON:0005090 ! muscle structure intersection_of: UBERON:0000062 ! organ intersection_of: composed_primarily_of UBERON:0002385 ! muscle tissue relationship: composed_primarily_of UBERON:0002385 ! muscle tissue relationship: part_of UBERON:0001015 ! musculature property_value: UBPROP:0000001 "Portion of tissue composed of contractile fibers.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005145", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "It seems clear that the metazoan ancestor inherited from its unicellular descendants an actin cytoskeleton and motor-proteins of the myosin superfamily. Within metazoans, these two molecules were arranged into effective contractile units, the muscles. The basic trends for muscle evolution are already expressed in the diploblastic taxa.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001245", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.75", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "muscular" xsd:string [Term] id: UBERON:0001637 name: artery namespace: uberon def: "An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]." [AEO:JB] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arterial subtree" EXACT [] synonym: "arterial system" RELATED [] synonym: "arterial tree organ part" EXACT [] synonym: "arterial vessel" RELATED [] synonym: "arteries" EXACT PLURAL [TAO:0000005] xref: AAO:0010211 xref: AEO:0000208 xref: BTO:0000573 xref: CALOHA:TS-0054 xref: EFO:0000814 xref: EHDAA2:0000143 xref: EHDAA2:0003253 xref: EMAPA:35147 xref: EV:0100026 xref: FMA:50720 xref: GAID:468 xref: galen:Artery xref: MA:0000064 xref: MAT:0000034 xref: MESH:D001158 xref: MIAA:0000034 xref: NCIT:C12372 xref: SCTID:362877004 xref: TAO:0000005 xref: UMLS:C0003842 {source="ncithesaurus:Artery"} xref: VHOG:0001251 xref: Wikipedia:Artery xref: XAO:0000114 xref: ZFA:0000005 is_a: UBERON:0003509 ! arterial blood vessel relationship: channels_from UBERON:0000948 ! heart property_value: editor_note "Note that in FMA an artery is a tree, whereas AEO/JB defines it as a tube; FMA includes a separate class for what it calls the trunk. Classification in this ontology may currently (Jan 2012) represent a mix of both schemes, although we are gradually revising in the direction of the AEO scheme." xsd:string property_value: UBPROP:0000001 "Part of the circulatory system composed of blood vessels which carry oxygenated blood away from the heart to the rest of the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010211", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001251", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "arterial" xsd:string property_value: UBPROP:0000012 "Some arthropods have primitive arterial systems but this term refers to arteries in a true closed circulatory system." xsd:string property_value: UBPROP:0000202 FMA:63812 [Term] id: UBERON:0001638 name: vein namespace: uberon def: "Any of the tubular branching vessels that carry blood from the capillaries toward the heart." [Wikipedia:Vein] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "vascular element" RELATED [EMAPA:th] synonym: "vena" RELATED LATIN [Wikipedia:Vein] synonym: "venae" RELATED PLURAL [VHOG:0001743] synonym: "venous subtree" BROAD [] synonym: "venous tree organ part" EXACT [] synonym: "venous vessel" BROAD [] xref: AAO:0010212 xref: AEO:0000209 xref: BTO:0000234 xref: CALOHA:TS-1108 xref: EFO:0000816 xref: EHDAA2:0003254 xref: EMAPA:35906 xref: EV:0100031 xref: FMA:50723 xref: GAID:492 xref: galen:Vein xref: MA:0000067 xref: MAT:0000037 xref: MESH:D014680 xref: MIAA:0000037 xref: NCIT:C12814 xref: SCTID:181367001 xref: TAO:0000082 xref: UMLS:C0042449 {source="ncithesaurus:Vein"} xref: VHOG:0001743 xref: Wikipedia:Vein xref: XAO:0000115 xref: ZFA:0000082 is_a: UBERON:0003920 ! venous blood vessel intersection_of: UBERON:0003920 ! venous blood vessel intersection_of: channel_for UBERON:0013756 ! venous blood relationship: channel_for UBERON:0013756 ! venous blood relationship: channels_from UBERON:0001982 ! capillary property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c2/Venous_system_en.svg" xsd:anyURI property_value: editor_note "TODO - check with MA - vein vs venous blood vessel" xsd:string property_value: UBPROP:0000001 "Part of the circulatory system composed of blood vessels which carry blood from other organs, tissues, and cells to the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010212", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001743", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "venous" xsd:string property_value: UBPROP:0000202 FMA:63814 [Term] id: UBERON:0001639 name: hepatic portal vein namespace: uberon def: "A portal vein that transports nutrients from the digestive tract to the liver[Kardong]." [http://sourceforge.net/tracker/?func=detail&aid=3091300&group_id=76834&atid=1205376, ISBN:0073040584, Wikipedia:Hepatic_portal_vein] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "hepatic portal tree" EXACT [] synonym: "HPV" RELATED [] synonym: "liver portal vein" EXACT [OBOL:automatic] synonym: "portal vein" RELATED INCONSISTENT [] synonym: "portal vein of liver" EXACT [OBOL:automatic] synonym: "primary hepatic portal vein" RELATED [ZFA:0005090] synonym: "primary hepatic portal veins" RELATED [] synonym: "vena portae hepatis" RELATED LATIN [Wikipedia:Hepatic_portal_vein] xref: AAO:0010214 xref: FMA:50735 xref: MA:0002132 xref: TAO:0005090 xref: VHOG:0000642 xref: Wikipedia:Hepatic_portal_vein xref: ZFA:0005090 is_a: UBERON:0002017 {source="MA"} ! portal vein relationship: channels_into UBERON:0002107 ! liver relationship: develops_from UBERON:0005487 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia:Vitelline_vein"} ! vitelline vein relationship: overlaps UBERON:0002107 ! liver relationship: part_of UBERON:0010194 ! hepatic portal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Adults of all vertebrates lose the vitelline veins and establish a single large hepatic portal vein (...) by the selective retention of parts of the left and right subintestinals and of several anastomoses that occur between them within and just posterior to the liver.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000642", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.265", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In humans A vein in the abdominal cavity that drains blood from the gastrointestinal tract and spleen. It is usually formed by the confluence of the superior mesenteric and splenic veins, and also receives blood from the inferior mesenteric, gastric, and cystic veins. The hepatic portal vein is a major component of the hepatic portal system, one of the main portal venous systems in the body. Conditions involving the hepatic portal vein cause considerable illness and death. An important example of such a condition is elevated blood pressure in the hepatic portal vein. This condition, called portal hypertension, is a major complication of cirrhosis worldwide. [WP,unvetted]" xsd:string [Term] id: UBERON:0001640 name: celiac artery namespace: uberon def: "The first major branch of the abdominal aorta." [Wikipedia:Celiac_artery] comment: dorsal aorta in Kardong subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "arteria coeliaca" RELATED LATIN [Wikipedia:Celiac_artery] synonym: "arteria cœliaca" RELATED LATIN [Wikipedia:Celiac_artery] synonym: "celiac tree" EXACT [] synonym: "celiac trunk" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac artery" EXACT [Wikipedia:Celiac_artery] synonym: "coeliac axis" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunck" RELATED [Wikipedia:Celiac_artery] synonym: "coeliac trunk" RELATED [Wikipedia:Celiac_artery] synonym: "truncus coeliacus" RELATED LATIN [Wikipedia:Celiac_artery] synonym: "truncus cœliacus" RELATED LATIN [Wikipedia:Celiac_artery] xref: EHDAA2:0004519 xref: EMAPA:35202 xref: FMA:50737 xref: GAID:483 xref: MA:0001931 xref: MESH:D002445 xref: NCIT:C52846 xref: SCTID:181340007 xref: UMLS:C0007569 {source="ncithesaurus:Coeliac_Artery"} xref: Wikipedia:Celiac_artery is_a: UBERON:0012254 ! abdominal aorta artery relationship: develops_from UBERON:0006002 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="Wikipedia"} ! vitelline artery relationship: indirectly_supplies UBERON:0000160 {source="ISBN:0073040584"} ! intestine relationship: indirectly_supplies UBERON:0000945 {source="ISBN:0073040584"} ! stomach relationship: indirectly_supplies UBERON:0002106 {source="ISBN:0073040584"} ! spleen relationship: indirectly_supplies UBERON:0002107 {source="ISBN:0073040584"} ! liver property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001645 name: trigeminal nerve namespace: uberon def: "Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw)." [ISBN:0471209627, Wikipedia:Trigeminal_nerve] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "5n" BROAD ABBREVIATION [BIRNLEX:869, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-V" RELATED [] synonym: "cranial nerve V" RELATED [] synonym: "fifth cranial nerve" EXACT [] synonym: "nerve V" RELATED [NeuroNames:549] synonym: "nervus trigeminus" EXACT LATIN [Wikipedia:Trigeminal_nerve] synonym: "nervus trigeminus" RELATED [BTO:0001072] synonym: "nervus trigeminus [v]" EXACT LATIN [FMA:50866, FMA:TA] synonym: "trigeminal nerve [V]" EXACT [] synonym: "trigeminal nerve tree" EXACT [] synonym: "trigeminal V" EXACT [EHDAA2:0002084] synonym: "trigeminal v nerve" EXACT [] synonym: "trigeminus" RELATED [BTO:0001072] xref: AAO:0010470 xref: BAMS:5n xref: BAMS:nV xref: BAMS:Vn xref: BIRNLEX:869 xref: BM:VN xref: BTO:0001072 xref: EFO:0001402 xref: EHDAA2:0002084 xref: EHDAA:3738 xref: EMAPA:17576 xref: FMA:50866 xref: GAID:726 xref: HBA:9322 xref: MA:0001100 xref: MBA:901 xref: MESH:D014276 xref: MFMO:0000093 xref: NCIT:C12806 xref: neuronames:549 {source="BIRNLEX:869"} xref: SCTID:362459002 xref: TAO:0000697 xref: UMLS:C0040996 {source="ncithesaurus:Trigeminal_Nerve", source="BIRNLEX:869"} xref: VHOG:0000704 xref: Wikipedia:Trigeminal_nerve xref: XAO:0003092 xref: ZFA:0000697 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001785 ! cranial nerve intersection_of: UBERON:0001785 ! cranial nerve intersection_of: extends_fibers_into UBERON:0002925 ! trigeminal nucleus intersection_of: innervates UBERON:0000165 ! mouth intersection_of: innervates UBERON:0011648 ! jaw muscle intersection_of: innervates UBERON:1000021 ! skin of face relationship: capable_of_part_of GO:0050964 {gci_relation="part_of", gci_filler="NCBITaxon:9255", source="PMID:22179203"} ! detection of electrical stimulus involved in electroception relationship: extends_fibers_into UBERON:0002925 ! trigeminal nucleus relationship: has_developmental_contribution_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon relationship: innervates UBERON:0000165 ! mouth relationship: innervates UBERON:0011648 ! jaw muscle relationship: innervates UBERON:1000021 ! skin of face property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/99/Gray778_Trigeminal.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Nerve consists of motor and sensory components. Ganglion cells of the sensory component form the proximal part of the trigeminal (Gasserian) ganglion. From the ganglion 3 major rami innervate jaws, snout, and buccal roof.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010470", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000704", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.625", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "the ophthalmic usually usually merges with the other two. In some vertebrates, the ophthalmic emerges from the brain separately[Kardong] The trigeminal nerve has 3 branches in mammals - similar branches are present in nonmammalian vertebrates, but in some a separate profundus nerve that corresponds to opthalmic branch in mammls" xsd:string {source="ISBN:0471888893"} [Term] id: UBERON:0001647 name: facial nerve namespace: uberon def: "Cranial nerve that branches into the supraorbital (supplying the skin of the eye region and the lateral line organs here), the palatine (to the roof of the buccal cavity), and the hyomandibular (dividing into the jugular and mental branches)." [ISBN:0471209627, Wikipedia:Facial_nerve] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "7n" BROAD ABBREVIATION [BIRNLEX:827, NIFSTD:NeuroNames_abbrevSource] synonym: "branchiomeric cranial nerve" EXACT [] synonym: "CN-VII" RELATED [] synonym: "cranial nerve VII" RELATED [] synonym: "face nerve" EXACT [OBOL:automatic] synonym: "facial nerve [VII]" EXACT [] synonym: "facial nerve or its root" RELATED [BAMS:7n] synonym: "facial nerve tree" EXACT [] synonym: "facial nerve/root" RELATED [BAMS:7n] synonym: "facial VII" EXACT [EHDAA2:0000489] synonym: "facial VII nerve" EXACT [] synonym: "nerve of face" EXACT [OBOL:automatic] synonym: "nerve VII" RELATED [NeuroNames:551] synonym: "nervus facialis" EXACT [ZFA:0000664] synonym: "nervus facialis" RELATED LATIN [Wikipedia:Facial_nerve] synonym: "nervus facialis [vii]" EXACT LATIN [FMA:50868, FMA:TA] synonym: "seventh cranial nerve" EXACT [] xref: AAO:0010472 xref: BAMS:7n xref: BAMS:nVII xref: BAMS:VIIn xref: BAMS:Viin xref: BIRNLEX:827 xref: BM:Pons-VIIN xref: EHDAA2:0000489 xref: EHDAA:3729 xref: EMAPA:17796 xref: FMA:50868 xref: GAID:719 xref: HBA:9328 xref: MA:0001091 xref: MBA:798 xref: MESH:D005154 xref: NCIT:C12714 xref: neuronames:551 {source="BIRNLEX:827"} xref: SCTID:362460007 xref: TAO:0000664 xref: UMLS:C0015462 {source="ncithesaurus:Facial_Nerve", source="BIRNLEX:827"} xref: VHOG:0000706 xref: Wikipedia:Facial_nerve xref: XAO:0003094 xref: ZFA:0000664 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001785 ! cranial nerve is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0001021 ! nerve intersection_of: extends_fibers_into UBERON:0000127 ! facial nucleus intersection_of: innervates UBERON:0001577 ! facial muscle relationship: extends_fibers_into UBERON:0000127 ! facial nucleus relationship: has_developmental_contribution_from UBERON:0003066 {source="Wikipedia"} ! pharyngeal arch 2 relationship: has_developmental_contribution_from UBERON:0005239 {source="Wikipedia"} ! basal plate metencephalon relationship: innervates UBERON:0001577 ! facial muscle relationship: part_of UBERON:0001033 {source="ZFA"} ! gustatory system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1f/Cranial_nerve_VII.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Slender nerve composed of branchiomotor and visceral efferent fibers innervating the mouth and various muscles within the jaw. Sensory components innervate the bucccal roof and somatomotor components innervate the depressor musculature and muscle interhyoideus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010472", ontology="AAO", source="AAO:DSM"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000706", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.625", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001649 name: glossopharyngeal nerve namespace: uberon def: "Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult)." [ISBN:0471209627, Wikipedia:Glossopharyngeal_nerve] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "9n" BROAD ABBREVIATION [BIRNLEX:899, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-IX" RELATED ABBREVIATION [] synonym: "cranial nerve IX" RELATED [] synonym: "glossopharyngeal IX" EXACT [EHDAA2:0000709] synonym: "glossopharyngeal IX nerve" EXACT [] synonym: "glossopharyngeal nerve [IX]" EXACT [] synonym: "glossopharyngeal nerve tree" EXACT [] synonym: "nerve IX" RELATED [NeuroNames:701] synonym: "nervus glossopharyngeus" EXACT [ZFA:0000668] synonym: "nervus glossopharyngeus" RELATED LATIN [Wikipedia:Glossopharyngeal_nerve] synonym: "nervus glossopharyngeus [ix]" EXACT LATIN [FMA:50870, FMA:TA] synonym: "ninth cranial nerve" EXACT [] xref: AAO:0010474 xref: BAMS:9n xref: BAMS:IXn xref: BIRNLEX:899 xref: BTO:0004979 xref: EHDAA2:0000709 xref: EHDAA:3733 xref: EMAPA:17268 xref: FMA:50870 xref: GAID:827 xref: HBA:9334 xref: MA:0001093 xref: MBA:808 xref: MESH:D005930 xref: NCIT:C12723 xref: neuronames:701 {source="BIRNLEX:899"} xref: SCTID:362465002 xref: TAO:0000668 xref: UMLS:C0017679 {source="BIRNLEX:899", source="ncithesaurus:Glossopharyngeal_Nerve"} xref: UMLS:C1305752 {source="BIRNLEX:899"} xref: VHOG:0000701 xref: Wikipedia:Glossopharyngeal_nerve xref: XAO:0003096 xref: ZFA:0000668 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001785 ! cranial nerve relationship: extends_fibers_into UBERON:0001896 ! medulla oblongata relationship: has_developmental_contribution_from UBERON:0005239 {notes="motor", source="Wikipedia"} ! basal plate metencephalon relationship: innervates UBERON:0001727 ! taste bud relationship: innervates UBERON:0006562 ! pharynx relationship: part_of UBERON:0001033 ! gustatory system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Small nerve consisting of branchiomotor and visceral efferent and afferent fibers which innervate the m. subarculais rectus I, dorsal buccal mucosa, and the tongue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010474", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000701", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.625", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001650 name: hypoglossal nerve namespace: uberon def: "Cranial nerve that innervates the muscles of the tongue." [http://orcid.org/0000-0002-6601-2165, ISBN:080184780X, VHOG:0000693] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "12n" BROAD ABBREVIATION [BIRNLEX:820, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-XII" RELATED [VHOG:0000693] synonym: "cranial nerve XII" EXACT [BIRNLEX:820] synonym: "hypoglossal nerve [XII]" EXACT [] synonym: "hypoglossal nerve tree" EXACT [] synonym: "hypoglossal nerve/ root" RELATED [BAMS:12n] synonym: "hypoglossal XII" EXACT [EHDAA2:0000798] synonym: "hypoglossal XII nerve" EXACT [] synonym: "nerve XII" RELATED [NeuroNames:704] synonym: "nervi hypoglossalis" RELATED LATIN [NeuroNames:704] synonym: "nervus hypoglossus" RELATED LATIN [Wikipedia:Hypoglossal_nerve] synonym: "nervus hypoglossus [xii]" EXACT LATIN [FMA:50871, FMA:TA] synonym: "twelfth cranial nerve" EXACT [] xref: AAO:0010477 xref: BAMS:12n xref: BAMS:nXII xref: BAMS:XIIn xref: BIRNLEX:820 xref: BTO:0003386 xref: EHDAA2:0000798 xref: EHDAA:2859 xref: EMAPA:17269 xref: FMA:50871 xref: GAID:828 xref: HBA:9343 xref: MA:0001094 xref: MBA:813 xref: MESH:D007002 xref: NCIT:C12732 xref: neuronames:704 {source="BIRNLEX:820"} xref: SCTID:362471008 xref: UMLS:C0020614 {source="BIRNLEX:820", source="ncithesaurus:Hypoglossal_Nerve"} xref: VHOG:0000693 xref: Wikipedia:Hypoglossal_nerve xref: XAO:0004215 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001785 ! cranial nerve intersection_of: UBERON:0001785 ! cranial nerve intersection_of: extends_fibers_into UBERON:0002871 ! hypoglossal nucleus intersection_of: innervates UBERON:0000378 ! tongue muscle relationship: extends_fibers_into UBERON:0002871 ! hypoglossal nucleus relationship: innervates UBERON:0001571 ! genioglossus muscle relationship: innervates UBERON:0001572 ! hyoglossus muscle relationship: innervates UBERON:3010654 {gci_relation="part_of", gci_filler="NCBITaxon:8292", source="ISBN:080184780X"} ! rectus cervicis relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ef/Gray794.png" xsd:anyURI property_value: RO:0002174 NCBITaxon:8292 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Cranial nerve that innervates muscles in the tongue. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-14, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000693", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "In amphibians, represents the hypoglossal nerve in amniotes. Innverates mm. geniohyoideus, genioglossus, hyoglossus, rectus cervicis" xsd:string {source="ISBN:080184780X"} property_value: UBPROP:0000001 "Nerve which innervates the muscles associated with the tongue including mm geniohyoideus, genioglossus, hyoglossus and rectus cervicis.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010477", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "Cranial nerves XI and XII evolved in the common ancestor to amniotes (non-amphibian tetrapods) thus totalling twelve pairs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000693", ontology="VHOG", source="Wikipedia:Cranial_nerves", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "we use a broad definition of this cranial nerve that encompasses the amphibian predecessor of true amniote hypoglossal nerves" xsd:string [Term] id: UBERON:0001651 name: right pulmonary artery namespace: uberon def: "The pulmonary artery that supplies the right lung." [UBERON:cjm] subset: human_reference_atlas subset: uberon_slim synonym: "arteria pulmonalis dextra" RELATED LATIN [Wikipedia:Right_pulmonary_artery] synonym: "right main pulmonary artery" EXACT [] synonym: "right pulmonary arterial tree" EXACT [] xref: EMAPA:37378 {source="MA:th"} xref: FMA:50872 xref: galen:RightPulmonaryArtery xref: MA:0002500 xref: NCIT:C33489 xref: SCTID:244235003 xref: UMLS:C0923924 {source="ncithesaurus:Right_Pulmonary_Artery"} xref: Wikipedia:Right_pulmonary_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002167 ! right lung relationship: connected_to UBERON:0002333 ! pulmonary trunk relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0002167 ! right lung property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI property_value: editor_note "TODO - add class 'pulmonary artery tree organ'" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001652 name: left pulmonary artery namespace: uberon def: "The pulmonary artery that supplies the left lung." [UBERON:cjm] subset: human_reference_atlas subset: uberon_slim synonym: "arteria pulmonalis sinistra" RELATED LATIN [Wikipedia:Left_pulmonary_artery] synonym: "left main pulmonary artery" EXACT [] synonym: "left pulmonary arterial tree" EXACT [] xref: EMAPA:37097 {source="MA:th"} xref: FMA:50873 xref: galen:LeftPulmonaryArtery xref: MA:0002032 xref: NCIT:C32971 xref: SCTID:244234004 xref: UMLS:C0923925 {source="ncithesaurus:Left_Pulmonary_Artery"} xref: Wikipedia:Left_pulmonary_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002168 ! left lung relationship: connected_to UBERON:0002333 ! pulmonary trunk relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0002168 ! left lung property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f6/Gray504.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI property_value: editor_note "TODO - add class 'pulmonary artery tree organ'" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001653 name: facial vein namespace: uberon def: "The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]." [Wikipedia:Facial_vein] subset: human_reference_atlas subset: uberon_slim synonym: "anterior facial vein" RELATED INCONSISTENT [Wikipedia:Facial_vein] synonym: "face vein" EXACT [OBOL:automatic] synonym: "vein of face" EXACT [OBOL:automatic] synonym: "vena facialis anterior" RELATED LATIN [Wikipedia:Facial_vein] xref: AAO:0010513 xref: EMAPA:19220 xref: FMA:50874 xref: MA:0002115 xref: NCIT:C32579 xref: SCTID:181374006 xref: UMLS:C0226532 {source="ncithesaurus:Facial_Vein"} xref: Wikipedia:Facial_vein is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0009141 ! craniocervical region vein relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001456 ! face relationship: tributary_of UBERON:0001586 {source="FMA"} ! internal jugular vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Vein which collects blood from muscles of the head and drains into the external jugular vein.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010513", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000012 "MA and NCITA also has 'anterior facial vein'" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001663 name: cerebral vein namespace: uberon def: "The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]." [Wikipedia:Cerebral_veins] subset: pheno_slim synonym: "venae cerebri" RELATED LATIN [Wikipedia:Cerebral_veins] synonym: "venae encephali" RELATED LATIN [Wikipedia:Cerebral_veins] xref: EMAPA:37140 {source="MA:th"} xref: FMA:50981 xref: GAID:530 xref: MA:0002096 xref: MESH:D002550 xref: NCIT:C53037 xref: SCTID:244392000 xref: UMLS:C0007797 {source="ncithesaurus:Cerebral_Vein"} xref: Wikipedia:Cerebral_veins xref: XAO:0004160 is_a: UBERON:0001638 ! vein is_a: UBERON:0003499 ! brain blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001893 ! telencephalon relationship: drains UBERON:0001893 ! telencephalon relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001893 ! telencephalon property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9f/Gray568.png" xsd:anyURI property_value: UBPROP:0000202 FMA:70861 [Term] id: UBERON:0001665 name: triceps surae namespace: uberon def: "The triceps surae is a pair of muscles located at the calf - the gastrocnemius and the soleus. These muscles both insert into the calcaneus, the bone of the heel of the human foot, and form the major part of the muscle of the back part of the lower leg, commonly known as the calf muscle. The triceps surae is connected to the foot through the Achilles tendon, and has 3 heads deriving from the 2 major masses of muscle. The superficial portion (the gastrocnemius) gives off 2 heads attaching to the base of the femur directly above the knee. The deep (profundis) mass of muscle (the soleus) forms the remaining head which attaches to the superior posterior area of the tibia. The triceps surae is innervated by the tibial nerve, specifically, nerve roots L5-S2. [WP,unvetted]." [Wikipedia:Triceps_surae_muscle] subset: uberon_slim synonym: "calf muscle" RELATED [Wikipedia:Triceps_surae_muscle] synonym: "gastrosoleus" RELATED [Wikipedia:Triceps_surae_muscle] synonym: "gastrosoleus complex" RELATED [Wikipedia:Triceps_surae_muscle] synonym: "musculus triceps surae" RELATED LATIN [Wikipedia:Triceps_surae_muscle] synonym: "sural triceps" RELATED [] xref: EMAPA:36267 xref: FMA:51062 xref: MA:0002400 xref: NCIT:C53181 xref: UMLS:C0224458 {source="ncithesaurus:Triceps_Surae"} xref: Wikipedia:Triceps_surae_muscle is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004256 ! hindlimb zeugopod muscle relationship: has_muscle_insertion UBERON:0001450 {source="dbpedia"} ! calcaneus relationship: has_muscle_insertion UBERON:0003701 {source="dbpedia"} ! calcaneal tendon relationship: innervated_by UBERON:0001323 {source="dbpedia"} ! tibial nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/57/Illu_lower_extremity_muscles.jpg" xsd:anyURI property_value: UBPROP:0000012 "A set of muscles in FMA, a single organ in MA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001675 name: trigeminal ganglion namespace: uberon def: "The cranial ganglion that is associated with and extends fibers into the trigeminal nerve." [http://orcid.org/0000-0002-6601-2165, http://www.ncbi.nlm.nih.gov/books/NBK53171, https://github.com/obophenotype/uberon/issues/693] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "5th ganglion" EXACT [ZFA:0000295] synonym: "fifth ganglion" EXACT [ZFA:0000295] synonym: "fused trigeminal ganglion" NARROW SENSU [NCBITaxon:32524] synonym: "ganglion of trigeminal complex" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ganglion of trigeminal nerve" RELATED [BTO:0001231] synonym: "ganglion semilunare" RELATED LATIN [Wikipedia:Trigeminal_ganglion] synonym: "ganglion trigeminale" RELATED LATIN [BTO:0001231, Wikipedia:Trigeminal_ganglion] synonym: "Gasser's ganglion" RELATED [BTO:0001231] synonym: "Gasserian ganglia" RELATED PLURAL [Wikipedia:Trigeminal_ganglion] synonym: "Gasserian ganglion" EXACT [Wikipedia:Trigeminal_ganglion] synonym: "gV" RELATED [] synonym: "semilunar ganglion" EXACT [ISBN:0471888893] synonym: "trigeminal ganglia" RELATED PLURAL [] synonym: "trigeminal V ganglion" EXACT [MA:0001080] synonym: "trigeminus ganglion" RELATED [] xref: AAO:0011107 xref: BAMS:5Gn xref: BAMS:GV xref: BTO:0001231 xref: EFO:0000903 xref: EHDAA2:0002085 xref: EHDAA:2113 xref: EMAPA:16797 xref: FMA:52618 xref: GAID:725 xref: MA:0001080 xref: MAT:0000511 xref: MESH:D012668 xref: NCIT:C62642 xref: neuronames:1402 xref: SCTID:244449009 xref: TAO:0000295 xref: UMLS:C0040995 {source="ncithesaurus:Trigeminal_Ganglion"} xref: VHOG:0000694 xref: Wikipedia:Trigeminal_ganglion xref: XAO:0000427 xref: XAO:0000428 xref: ZFA:0000295 is_a: UBERON:0001714 ! cranial ganglion is_a: UBERON:0001800 {source="ncithesaurus"} ! sensory ganglion is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001714 ! cranial ganglion intersection_of: extends_fibers_into UBERON:0001645 ! trigeminal nerve relationship: develops_from UBERON:0006304 ! future trigeminal ganglion relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/ANiknejad relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: immediate_transformation_of UBERON:0006304 {source="Bgee:AN"} ! future trigeminal ganglion property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/69/Gray776.png" xsd:anyURI property_value: editor_note "consider renaming this 'trigeminal ganglion complex'. The complex may be fused (amniotes) partially fused (xenopus) or separate (sharks)" xsd:string property_value: UBPROP:0000001 "A prominent collection of touch-sensory neurons of the trigeminal or fifth cranial nerve, positioned beside the brain between the eye and the ear. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000295", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000008 "In Xenopus, the profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24." xsd:string {source="PMID:21452441", source="XAO:0004093"} [Term] id: UBERON:0001676 name: occipital bone namespace: uberon def: "The bone at the lower, posterior part of the skull." [ISBN:0-683-40008-8, MP:0005269] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "occipital complex" RELATED [http://palaeos.com/vertebrates/bones/braincase/occiput.html] synonym: "occipital squama" RELATED [] synonym: "os occipitale" RELATED LATIN [Wikipedia:Occipital_bone] xref: EMAPA:25112 xref: FMA:52735 xref: GAID:227 xref: MA:0001468 xref: MESH:D009777 xref: NCIT:C12757 xref: SCTID:181796003 xref: UMLS:C0028784 {source="ncithesaurus:Occipital_Bone"} xref: Wikipedia:Occipital_bone is_a: UBERON:0010428 {source="FMA"} ! flat bone is_a: UBERON:0011164 ! neurocranium bone relationship: connected_to UBERON:0001092 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vertebral bone 1 relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone relationship: develops_from UBERON:0003089 {source="PMID:11523816"} ! sclerotome relationship: only_in_taxon NCBITaxon:117570 {source="WP"} ! Teleostomi relationship: overlaps UBERON:0002241 {notes="basi paired exo and supra occipital bones", source="MA-modified"} ! chondrocranium relationship: overlaps UBERON:0003113 {notes="interparietal (postparietal)"} ! dermatocranium relationship: part_of UBERON:0005902 {source="FMA"} ! occipital region relationship: surrounds UBERON:0003687 ! foramen magnum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/27/Gray194.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "formed from the sclerotome of the occipital somites. It is not present in living or fossil agnathans or cartilaginous fishes, but appears to have arisen in parallel in many bony fishes. Incorporation of the occipital ver- tebrae into the skull was associated with the annexation of the upper part of the spinal cord into the brain, together with the first 2 spinal nerves as cranial nerves XI and XII" xsd:string {source="PMID:11523816"} property_value: UBPROP:0000008 "fusion of basi-, exo- and supra-occipitals (and maybe tabular)" xsd:string {source="Kardong"} [Term] id: UBERON:0001677 name: sphenoid bone namespace: uberon def: "An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended." [Wikipedia:Sphenoid_bone] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "butterfly bone" RELATED [Wikipedia:Sphenoid_bone] synonym: "os sphenoidale" EXACT LATIN [FMA:52736, FMA:TA] synonym: "os sphenoidale" RELATED LATIN [Wikipedia:Sphenoid_bone] synonym: "os sphenoidum" RELATED [Wikipedia:Sphenoid_bone] synonym: "sphenoid" EXACT [] synonym: "sphenoid complex" RELATED [] synonym: "sphenoidal bone" EXACT [] xref: CALOHA:TS-2343 xref: EMAPA:18340 xref: FMA:52736 xref: GAID:230 xref: MA:0001472 xref: MESH:D013100 xref: NCIT:C12790 xref: SCTID:272676008 xref: UMLS:C0037884 {source="ncithesaurus:Sphenoid_Bone"} xref: Wikipedia:Sphenoid_bone is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0003462 ! facial bone is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone is_a: UBERON:0015060 ! sphenoid endochondral element intersection_of: UBERON:0015060 ! sphenoid endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: connected_to UBERON:0000209 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tetrapod frontal bone relationship: connected_to UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! occipital bone relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid bone relationship: connected_to UBERON:0002396 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vomer relationship: develops_from UBERON:0009193 {source="cjm"} ! sphenoid cartilage element relationship: overlaps UBERON:0002241 {notes="orbito pre and basi sphenoid"} ! chondrocranium relationship: overlaps UBERON:0003113 {notes="pterygoid process"} ! dermatocranium relationship: overlaps UBERON:0008895 {notes="alisphenoid"} ! splanchnocranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "part of viscerocranium (facial skeleton) in FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001678 name: temporal bone namespace: uberon def: "The large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous." [ISBN:0-683-40008-8, MP:0005272] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "os temporale" RELATED LATIN [Wikipedia:Temporal_bone] xref: EHDAA:6035 xref: EMAPA:17682 xref: FMA:52737 xref: GAID:232 xref: MA:0001476 xref: MESH:D013701 xref: NCIT:C12797 xref: SCTID:181795004 xref: UMLS:C0039484 {source="ncithesaurus:Temporal_Bone"} xref: VHOG:0000800 xref: Wikipedia:Temporal_bone is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone relationship: overlaps UBERON:0002241 {notes="petrosal"} ! chondrocranium relationship: overlaps UBERON:0003113 {notes="squamosal plus angular", notes="temporal series"} ! dermatocranium relationship: overlaps UBERON:0008895 {notes="styloid process"} ! splanchnocranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "fusion of squamosal + angular (tympanic annulus) [derm.] + petrosal (prootic + opisthotic)" xsd:string {source="chond."} property_value: UBPROP:0000008 "In many mammals, as in humans, the petrosal, ectotympanic and squamosal bones synostose to form the temporal bone + styloid process" xsd:string property_value: UBPROP:0000010 "The temporal bone consists of four parts: * Squama temporalis * Mastoid portion * Petrous portion (Petrosal ridge) * Tympanic part[WP]." xsd:string {source="[WP]"} property_value: UBPROP:0000012 "Note the Temporal bone is not explicitly categorized to a part of the cranium in FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001679 name: ethmoid bone namespace: uberon def: "A bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP]." [Wikipedia:Ethmoid_bone] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "ethmoid" EXACT [FMA:52740] synonym: "ethmoidal bone" EXACT [MP:0000101] synonym: "os ethmoidale" EXACT LATIN [FMA:52740, FMA:TA, Wikipedia:Ethmoid] xref: BTO:0004140 xref: EMAPA:19018 xref: FMA:52740 xref: GAID:212 xref: MA:0001483 xref: MESH:D005004 xref: NCIT:C12711 xref: SCTID:272674006 xref: UMLS:C0015027 {source="ncithesaurus:Ethmoid_Bone"} xref: VHOG:0001317 xref: Wikipedia:Ethmoid_bone is_a: UBERON:0002513 {source="ISBN:0073040584"} ! endochondral bone is_a: UBERON:0003462 ! facial bone is_a: UBERON:0011164 ! neurocranium bone relationship: connected_to UBERON:0000209 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! tetrapod frontal bone relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone relationship: connected_to UBERON:0002396 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! vomer relationship: contributes_to_morphology_of UBERON:0011156 ! facial skeleton relationship: develops_from UBERON:0006227 {evidence="definitional"} ! ethmoid bone primordium relationship: part_of UBERON:0002517 ! basicranium relationship: part_of UBERON:0011241 ! ethmoid region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cranial_bones2.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A light spongy bone located between the eye sockets, forming part of the walls and septum of the superior nasal cavity, and containing perforations for the passage of olfactory nerve fibers. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001317", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/ethmoid+bone"} property_value: UBPROP:0000003 "The ethmoid region of the chondrocranium and the nasal capsules, which were largely unossified in early tetrapods and ancestral amniotes, are represented in mammals by the ethmoid and turbinates bones, respectively.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001317", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.259", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "ethmoidal" xsd:string property_value: UBPROP:0000008 "todo - homology e.g. mesethmoid of teleost" xsd:string property_value: UBPROP:0000012 "Note the WP states the Neurocranium contains the ethmoid bone, both MA and FMA place the ethmoid as part of the viscerocranium. FMA also has it in neurocranium (via basicranium). Ideally we would have non-overlapping divisions of the skull, but for now we follow FMA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001681 name: nasal bone namespace: uberon def: "One of two small oblong bones, varying in size and form in different individuals; they are placed side by side at the middle and upper part of the face, and form, by their junction, 'the bridge' of the nose[WP]. Paired dermal bones, likened to a bone tube, positioned lateral to the supraethmoid. Nasal bones are transversed by the anterior most part of the supraorbital canals and bear one neuromast foramen in zebrafish[ZFA]." [https://github.com/obophenotype/uberon/issues/265, Wikipedia:Nasal_bone, ZFIN:curator] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nasal bones" RELATED PLURAL [ZFA:0000365] synonym: "nasals" RELATED PLURAL [TAO:0000365] synonym: "os nasale" RELATED LATIN [Wikipedia:Nasal_bone] xref: AAO:0000312 xref: EMAPA:19202 xref: FMA:52745 xref: GAID:222 xref: MA:0001494 xref: MESH:D009295 xref: NCIT:C33157 xref: SCTID:181801008 xref: TAO:0000365 xref: UMLS:C0027422 {source="ncithesaurus:Nasal_Bone"} xref: VHOG:0001370 xref: Wikipedia:Nasal_bone xref: ZFA:0000365 is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0003462 ! facial bone is_a: UBERON:0008907 ! dermal bone is_a: UBERON:0010428 {source="FMA"} ! flat bone is_a: UBERON:0015212 ! lateral structure relationship: contributes_to_morphology_of UBERON:0011156 ! facial skeleton relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton relationship: part_of UBERON:0000004 ! nose relationship: part_of UBERON:0003113 {notes="facial series", source="ISBN:0073040584"} ! dermatocranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Paired bone of intramembranous origin that roofs the olfactory capsule.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000312", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "Paired dermal bones, likened to a bone tube, positioned lateral to the supraethmoid. Nasal bones are transversed by the anterior most part of the supraorbital canals and bear one neuromast foramen in zebrafish Cubbage and Mabee, 1996.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000365", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: overlaps mesethmoid-nasal joint (TAO:0001677)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000365", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000312", ontology="AAO"} property_value: UBPROP:0000005 "Synonym adnasal used in Weitzman 1960, and synonym discussed in Vari 1995.[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0000365", ontology="TAO", source="Curator"} property_value: UBPROP:0000008 "In primitive bony fish and tetrapods, the nasal bones are the most anterior of a set of four paired bones forming the roof of the skull, being followed in sequence by the frontals, the parietals, and the postparietals. Their form in living species is highly variable, depending on the shape of the head, but they generally form the roof of the snout or beak, running from the nostrils to a position short of the orbits. In most animals, they are generally therefore proportionally larger than in humans or great apes, because of the shortened faces of the latter. Turtles, unusually, lack nasal bones, with the prefrontal bones of the orbit reaching all the way to the nostrils (ISBN 0-03-910284-X)" xsd:string [Term] id: UBERON:0001682 name: palatine bone namespace: uberon def: "A paired dermal bone situated in the mid-palate that helps form the hard palate [Palaeos]." [http://palaeos.com/vertebrates/bones/dermal/palatal-palatines.html, Wikipedia:Palatine_bone] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "dermopalatine" NARROW [http://palaeos.com/vertebrates/glossary/glossaryD.html] synonym: "os palatinum" RELATED LATIN [] synonym: "palate bone" RELATED [] synonym: "palatine" EXACT [] synonym: "palatum" RELATED [Wikipedia:Palatine_bone] xref: EMAPA:36619 xref: FMA:52746 xref: http://palaeos.com/vertebrates/bones/dermal/images/289x311xPalatine1.gif.pagespeed.ic.tglmNBrF4D.png xref: MA:0001495 xref: NCIT:C52745 xref: SCTID:244654005 xref: TAO:0000015 xref: UMLS:C0222734 {source="ncithesaurus:Palatine_Bone"} xref: Wikipedia:Palatine_bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0011597 ! bone of upper jaw is_a: UBERON:0012071 ! palate bone is_a: UBERON:0015212 ! lateral structure relationship: connected_to UBERON:0002397 ! maxilla relationship: contributes_to_morphology_of UBERON:0011156 ! facial skeleton relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton relationship: in_lateral_side_of UBERON:0012072 {source="ISBN:0073040584"} ! palatal part of dermatocranium relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0011085 ! palatoquadrate arch relationship: part_of UBERON:0012074 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! bony part of hard palate property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/44/Gray996.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:32519 {source="TAO"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dermal bone that forms the antero-lateral region of the palate and is located ventral to the autopalatine. The dermopalatine is bilaterally paired and usually bears teeth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000015", ontology="TAO", source="TAO:GA_TG"} property_value: UBPROP:0000005 "Dermopalatine: same as palatine. The prefix is used by fish people because the palatine is a dermal replacement bone for a section of the autopalatine section of the palatoquadrate. In that context, palatine is potentially ambiguous.[Palaeos]" xsd:string {date_retrieved="2012-09-17", source="http://palaeos.com/vertebrates/glossary/glossaryD.html"} property_value: UBPROP:0000005 "In ostariophysans, the dermopalatine is absent.[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0000015", ontology="TAO", source="Curator"} property_value: UBPROP:0000008 "Fusion of dermopalatine+autopalatine." xsd:string [Term] id: UBERON:0001685 name: hyoid bone namespace: uberon def: "A horseshoe shaped bone situated in the anterior midline of the neck between the chin and the thyroid cartilage. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. [WP,modified]." [Wikipedia:Hyoid_bone] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "hyoid" RELATED [Wikipedia:Hyoid_bone] synonym: "hyoid bone" RELATED [Wikipedia:Hyoid_bone] synonym: "hyoideum" RELATED [Wikipedia:Hyoid_bone] synonym: "lingual bone" RELATED [Wikipedia:Hyoid_bone] synonym: "os hyoideum" RELATED LATIN [Wikipedia:Hyoid_bone] xref: AAO:0000684 xref: EMAPA:18650 xref: FMA:52749 xref: GAID:197 xref: MA:0001484 xref: MESH:D006928 xref: NCIT:C32752 xref: SCTID:263352000 xref: UMLS:C0020417 {source="ncithesaurus:Hyoid_Bone"} xref: VHOG:0001325 xref: Wikipedia:Hyoid_bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone relationship: has_developmental_contribution_from UBERON:0003066 {source="Wikipedia"} ! pharyngeal arch 2 relationship: has_developmental_contribution_from UBERON:0003114 {source="Wikipedia"} ! pharyngeal arch 3 relationship: part_of UBERON:0010272 ! hyoid apparatus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1f/Gray186.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Paired processes that extend posterolaterally from the posterior margin of the hyoid plate. These processes are the ossified posteromedial processes and invest the laryngeal apparatus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000684", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: part_of hyoid plate (AAO:0000664)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000684", ontology="AAO"} property_value: UBPROP:0000008 "The hyoid bone is derived from the lower half of the second gill arch in fish, which separates the first gill slit from the spiracle. In many animals, it also incorporates elements of other gill arches, and has a correspondingly greater number of cornua. Amphibians and reptiles may have many cornua, while mammals (including humans) have two pairs, and birds only one. In birds, and some reptiles, the body of the hyoid is greatly extended forward, creating a solid bony support for the tongue. The howler monkey Alouatta has a pneumatized hyoid bone, one of the few cases of postcranial pneumatization of bones outside Saurischia." xsd:string {seeAlso="https://github.com/obophenotype/uberon/issues/548", source="WP"} [Term] id: UBERON:0001686 name: auditory ossicle bone namespace: uberon def: "One of 3 small bones contained within the middle ear space and serve to transmit sounds from the air to the fluid-filled labyrinth. The absence of the auditory ossicles would constitute a moderate-to-severe hearing loss. The term 'ossicles' literally means 'tiny bones' and commonly refers to the auditory ossicles, though the term may refer to any small bone throughout the body. [WP,unvetted]." [https://github.com/obophenotype/uberon/issues/91, Wikipedia:Auditory_ossicle] subset: pheno_slim subset: uberon_slim synonym: "auditory bone" EXACT [] synonym: "auditory ossicle" RELATED [MA:0000254] synonym: "ear bone" RELATED [MA:0000254] synonym: "ear ossicle" RELATED [] synonym: "ear ossicles" RELATED PLURAL [] synonym: "middle ear bone" RELATED [] synonym: "middle ear ossicle" EXACT [MP:0005105] synonym: "ossicle" BROAD [EMAPA:17824, Wikipedia:Auditory_ossicle] synonym: "ossicle of ear" RELATED [] synonym: "ossicle of inner ear" RELATED [] synonym: "ossicular chain" RELATED PLURAL [] xref: AAO:0011015 xref: EHDAA2:0001183 xref: EHDAA:5697 xref: EMAPA:17824 xref: EV:0100360 xref: FMA:52750 xref: MA:0000254 xref: NCIT:C32164 xref: SCTID:181184001 xref: UMLS:C0013450 {source="ncithesaurus:Auditory_Ossicle"} xref: VHOG:0000461 xref: Wikipedia:Auditory_ossicle xref: XAO:0000214 is_a: UBERON:0003457 ! head bone is_a: UBERON:0035130 ! auditory ossicle endochondral element intersection_of: UBERON:0035130 ! auditory ossicle endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b0/Illu_auditory_ossicles.jpg" xsd:anyURI property_value: editor_note "This should probably be restricted to mammals - the AAO/XAO structures may group non-homologous structures [Wikipedia:Evolution_of_mammalian_auditory_ossicles] see https://github.com/seger/aao/issues/5." xsd:string property_value: UBPROP:0000001 "The small bones of the middle ear: incus, malleus, and stapes. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000461", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/auditory+ossicles"} property_value: UBPROP:0000003 "Additional structural analysis within a phylogenetic context has led to the remarkable discovery that in synapsids, thought to be ancestral to mammals, both the quadrate and articular have become reduced and less firmly articulated with their surrounding bones, reducing their jaw-joint-bearing role. This trend culminated with the incorporation of the quadrate, the columella (which remains articulated with the quadrate), and the articular into the expanded middle ear in mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000461", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.695", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "Studies have shown that ear bones in mammal embryos are attached to the dentary, which is part of the jaw. These are ossified portions of cartilage -- called Meckel's cartilage -- that are attached to the jaw. As the embryo develops, the cartilage hardens to form bone. Later in development, the bone structure breaks loose from the jaw and migrates to the inner ear area. The structure is known as the middle ear, and is made up of the incus, stapes, malleus, and tympanic membrane. These correspond to the quadrate, prearticular, articular, and angular structures in the reptile jaw. For this reason, researchers believe the similarity of the results shows that mammals and reptiles have a common ancestry." xsd:string {source="WP"} [Term] id: UBERON:0001690 name: ear namespace: uberon def: "Sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals." [GO:0042471, Wikipedia:Ear] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "auditory apparatus" RELATED [] synonym: "auris" RELATED [BTO:0000368] xref: AAO:0011014 xref: BIRNLEX:1062 xref: BTO:0000368 xref: CALOHA:TS-1165 xref: EFO:0000826 xref: EHDAA2:0000423 xref: EHDAA:502 xref: EMAPA:16193 xref: EV:0100353 xref: FMA:52780 xref: GAID:62 xref: galen:Ear xref: MA:0000236 xref: MAT:0000138 xref: MESH:D004423 xref: MIAA:0000138 xref: NCIT:C12394 xref: SCTID:1910005 xref: UMLS:C0013443 {source="ncithesaurus:Ear", source="BIRNLEX:1062"} xref: UMLS:C0521421 {source="BIRNLEX:1062"} xref: VHOG:0000330 xref: Wikipedia:Ear xref: XAO:0000189 is_a: UBERON:0000020 ! sense organ is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: capable_of GO:0050910 ! detection of mechanical stimulus involved in sensory perception of sound relationship: part_of UBERON:0000033 ! head relationship: part_of UBERON:0002105 ! vestibulo-auditory system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b8/Ear.jpg" xsd:anyURI property_value: UBPROP:0000001 "The organ of hearing and of equilibrium. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000330", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/ear"} property_value: UBPROP:0000003 "Both vertebrate and invertebrate auditory organs are thought to have evolved from primitive mechanosensors, but the nature of the ancestral structure and the evolutionary trajectories followed in distinct animal lineages remain unknown. In particular, we do not know how many types of mechanosensor existed in the protostome-deuterostome ancestor from which insects and vertebrates evolved or whether the PDA had an auditory organ.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000330", ontology="VHOG", source="DOI:10.1002/dvdy.20207 Boekhoff-Falk G, Hearing in Drosophila: Development of Johnston's organ and emerging parallels to vertebrate ear development. Developmental Dynamics (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "auricular" xsd:string [Term] id: UBERON:0001691 name: external ear namespace: uberon def: "Part of the ear external to the tympanum (eardrum). It typically consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull[GO]." [GO:0042473, Wikipedia:External_ear] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "auricular region" BROAD [] synonym: "auricular region of head" EXACT [] synonym: "auris externa" RELATED [BTO:0002100] synonym: "outer ear" EXACT [MA:0000258] xref: AAO:0011037 xref: BIRNLEX:1705 xref: BTO:0002100 xref: EFO:0004221 xref: EHDAA2:0000462 xref: EHDAA:3786 xref: EMAPA:16991 xref: EV:0100354 xref: FMA:52781 xref: GAID:104 xref: MA:0000258 xref: MAT:0000147 xref: MESH:D004431 xref: MIAA:0000147 xref: NCIT:C12292 xref: SCTID:420893000 xref: UMLS:C0013453 {source="ncithesaurus:External_Ear", source="BIRNLEX:1705"} xref: UMLS:C1269548 {source="BIRNLEX:1705"} xref: VHOG:0000311 xref: Wikipedia:External_ear xref: XAO:0000190 is_a: UBERON:0001444 ! subdivision of head is_a: UBERON:0015212 ! lateral structure relationship: contributes_to_morphology_of UBERON:0000033 ! head relationship: contributes_to_morphology_of UBERON:0001690 ! ear relationship: in_lateral_side_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of UBERON:0001690 ! ear property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Gray907.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:9709 {source="Wikipedia"} property_value: UBPROP:0000001 "The external part of the organ, which consists of an outer portion (external auditory meatus) which leads to the tympanum. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000311", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "Some species, like Amolops tormotus (Feng et al. 2006), have a cavity in front of the tympanic membrane which is considered to be an ear canal and thus an outer ear. (...) The ancestral lineage of amphibians separated from the mammalian lineage, approximately 350 million years ago, in the paleozoic era. Many of the important developments in the auditory systems emerged after the ancestral paths separated (Manley and Clack 2003). This implies that shared features, like the tympanic middle ear, developed independently in different vertebrate lineages.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000311", ontology="VHOG", source="DOI:10.1007/s00359-008-0327-1 Schoffelen RLM, Segenhout JM, Van Dijk P, Mechanics of the exceptional anuran ear. Journal of Comparative Physiology A (2008)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in XAO this includes and is only the tympanum" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0001697 name: orbit of skull namespace: uberon def: "Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball." [http://orcid.org/0000-0002-6601-2165, TAO:0001410, Wikipedia:Orbit_(anatomy)] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bony orbit" EXACT [] synonym: "eye socket" EXACT [] synonym: "orbit" RELATED [ZFA:0001410] synonym: "orbit of skull" EXACT [FMA:53074] xref: BTO:0004687 xref: FMA:53074 xref: GAID:223 xref: galen:Orbit xref: MA:0002482 xref: MESH:D009915 xref: NCIT:C12347 xref: TAO:0001410 xref: UMLS:C0029180 {source="ncithesaurus:Orbit"} xref: Wikipedia:Orbit_(anatomy) xref: XAO:0003171 xref: ZFA:0001410 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton is_a: UBERON:0015212 ! lateral structure relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton relationship: location_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0004088 ! orbital region relationship: part_of UBERON:0011156 ! facial skeleton property_value: UBPROP:0000001 "Anatomical cluster that is a anterolateral part of the cranium and structurally supports the eye.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001410", ontology="TAO", source="TAO:MAH"} property_value: UBPROP:0000012 "in FMA, this overlaps with bones such as the maxilla and sphenoid; in ZFA, individual bones are part of the orbit" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001700 name: geniculate ganglion namespace: uberon def: "The group of sensory neuron cell bodies associated with the facial nerve (seventh cranial nerve)." [ISBN:0-683-40008-8, MP:0001082] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "facial ganglion" RELATED [ZFA:0001291] synonym: "facial VII ganglion" EXACT [MA:0001076] synonym: "ganglion genicularum" EXACT [FMA:53414] synonym: "ganglion geniculi" RELATED [Wikipedia:Geniculate_ganglion] synonym: "ganglion geniculi nervi facialis" RELATED LATIN [Wikipedia:Geniculate_ganglion] synonym: "genicular ganglion" EXACT [FMA:53414, Wikipedia:Geniculate_ganglion] synonym: "geniculate" BROAD [Wikipedia:Geniculate_ganglion] synonym: "geniculate ganglion" RELATED [MA:0001076] synonym: "gVII" EXACT [ZFA:0001291] synonym: "internal genu" RELATED [Wikipedia:Geniculate_ganglion] xref: BAMS:GgVII xref: EFO:0003669 xref: EHDAA2:0000491 xref: EHDAA2:0004623 xref: EHDAA:5567 xref: EHDAA:6644 xref: EMAPA:17569 xref: FMA:53414 xref: GAID:718 xref: MA:0001076 xref: MESH:D005830 xref: NCIT:C12721 xref: neuronames:1535 xref: SCTID:279076005 xref: TAO:0001291 xref: UMLS:C0017406 {source="ncithesaurus:Geniculate_Ganglion"} xref: VHOG:0000707 xref: Wikipedia:Geniculate_ganglion xref: ZFA:0001291 is_a: UBERON:0001800 {source="ncithesaurus"} ! sensory ganglion is_a: UBERON:0009127 ! epibranchial ganglion is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001714 ! cranial ganglion intersection_of: extends_fibers_into UBERON:0001647 ! facial nerve relationship: develops_from UBERON:0009124 {source="EHDAA2:0004623", source="ZFA"} ! geniculate placode relationship: develops_from UBERON:0010258 {source="EHDAA2:0004623"} ! mesenchyme from rhombencephalic neural crest relationship: develops_from UBERON:0012175 {source="EHDAA2:0000491"} ! acoustico-facial VII-VIII ganglion complex relationship: extends_fibers_into UBERON:0001647 ! facial nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray789.png" xsd:anyURI property_value: editor_note "resolve facial VII vs geniculate (see EHDAA2)" xsd:string property_value: UBPROP:0000003 "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000707", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001701 name: glossopharyngeal ganglion namespace: uberon def: "The group of neuron cell bodies associated with the ninth cranial nerve." [MP:0001096] subset: pheno_slim subset: vertebrate_core synonym: "ganglion of glossopharyngeal nerve" EXACT [] synonym: "ganglion of glosspharyngeal nerve" EXACT [FMA:53471] synonym: "gIX" RELATED [] synonym: "glossopharyngeal IX ganglion" EXACT [MA:0001077] synonym: "petrosal ganglion" NARROW [ZFA:0001301] xref: EHDAA2:0000710 xref: EHDAA:2838 xref: EMAPA:16795 xref: FMA:53471 xref: MA:0001077 xref: SCTID:244451008 xref: TAO:0001301 xref: VHOG:0000702 xref: ZFA:0001301 is_a: UBERON:0009127 {source="ZFA"} ! epibranchial ganglion intersection_of: UBERON:0001714 ! cranial ganglion intersection_of: extends_fibers_into UBERON:0001649 ! glossopharyngeal nerve relationship: extends_fibers_into UBERON:0001649 ! glossopharyngeal nerve relationship: has_developmental_contribution_from UBERON:0005491 {notes="dorsal", source="EHDAA2", source="ISBN:0471888893", source="ZFA"} ! glossopharyngeal neural crest relationship: has_developmental_contribution_from UBERON:0009125 {notes="ventrolateral", source="EHDAA2", source="ISBN:0471888893", source="ZFA"} ! petrosal placode property_value: UBPROP:0000003 "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000702", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001703 name: neurocranium namespace: uberon def: "Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof." [PMID:11523816, TAO:MAH, Wikipedia:Neuroranium, ZFA:0001580] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "brain box" EXACT [] synonym: "brain case" RELATED [ZFA:0001580] synonym: "brain pan" RELATED [http://www.thefreedictionary.com/braincase] synonym: "braincase" RELATED [ZFA:0001580] xref: AAO:0010153 xref: EHDAA2:0000243 xref: EMAPA:17681 xref: FMA:53672 xref: MA:0000317 xref: SCTID:361731002 xref: TAO:0001580 xref: Wikipedia:Neuroranium xref: XAO:0003170 xref: ZFA:0001580 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011158 {source="FMA"} ! primary subdivision of skull relationship: develops_from UBERON:0004761 ! cartilaginous neurocranium relationship: location_of UBERON:0000955 ! brain relationship: part_of UBERON:0003128 ! cranium relationship: protects UBERON:0000955 ! brain property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical cluster that consists of the cartilages and bones that surround the brain.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001580", ontology="TAO", source="TAO:MAH"} property_value: UBPROP:0000007 "neurocranial" xsd:string property_value: UBPROP:0000010 "It includes the following bones: Ethmoid bone, Frontal bone, Occipital bone, Parietal bone, Sphenoid bone, Temporal bone. The term cranium can be ambiguous, in that it can refer to the neurocranium, or the neurocranium and the Facial skeleton" xsd:string property_value: UBPROP:0000011 "The cartilaginous parts of the neurocranium undergo endochondral ossification in most species; ossification has been lost in cartilaginous fishes, but the cartilaginous condition of the skull of lampreys is considered to be primitive (Kardong, 1995)[PMID:11523816]. The neurocranium arises from paraxial mesoderm in the head (first five somites and the unsegmented somitomeres rostral to the first somite) and from ectoderm via the neural crest. In Chondrichthyes and other cartilaginous vertebrates this portion of the cranium does not ossify; it is not replaced via endochondral ossification[WP]." xsd:string {source="WP"} property_value: UBPROP:0000012 "It seems MA uses 'neurocranium' as a synonym for chondrocranium. Note there are currently some structures part of both viscero and neurocranium - ethmoid, zyogomatic, ..." xsd:string {external_ontology="MA"} [Term] id: UBERON:0001705 name: nail namespace: uberon def: "A horn-like keratin structure covering the dorsal aspect of the terminal phalanges of fingers and toes[WP]." [https://github.com/obophenotype/uberon/issues/120, Wikipedia:Nail_(anatomy)] comment: The nails of humans and the claws are moth are highly similar. Both species have a proximal nail fold, cuticle, nail matrix, nail bed, nail plate, and hyponychium. Distinguishing features are the shape of the nail and the presence of an extended hyponychium in the mouse [PMC3579226] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "claw" NARROW SENSU [Wikipedia:Claw] synonym: "nail/claw" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "talon" RELATED [] xref: BTO:0001719 xref: CALOHA:TS-2034 xref: EFO:0000956 xref: EMAPA:35580 xref: EV:0100159 xref: FMA:54326 xref: GAID:1320 xref: galen:Nail xref: MA:0002703 xref: MAT:0000158 xref: MESH:D009262 xref: MIAA:0000158 xref: NCIT:C33156 xref: SCTID:72651009 xref: UMLS:C0027342 {source="ncithesaurus:Nail"} xref: VHOG:0001361 xref: Wikipedia:Nail_(anatomy) is_a: UBERON:0009564 ! distal limb integumentary appendage relationship: composed_primarily_of GO:0045095 ! keratin filament relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly property_value: IAO:0000232 "Use this class for both the nails of primates and the homologous claws of mammals such as mouse." xsd:string property_value: UBPROP:0000008 "A primate's nail consists of the unguis alone; the subunguis has disappeared" xsd:string [Term] id: UBERON:0001707 name: nasal cavity namespace: uberon def: "An anatomical cavity that is part of the olfactory apparatus. This includes the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cavitas nasalis" RELATED [BTO:0002096] synonym: "cavitas nasi" RELATED LATIN [BTO:0002096, Wikipedia:Nasal_cavity] synonym: "cavity of nose" EXACT [] synonym: "cavity of olfactory apparatus" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "cavum nasi" RELATED LATIN [Wikipedia:Nasal_cavity] synonym: "nasal canal" EXACT [ZFA:0000130] synonym: "nasal conduit space" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "nasal fossa" EXACT [Wikipedia:Nasal_cavity] synonym: "nasal pit" RELATED [] synonym: "olfactory cavity" RELATED [] synonym: "olfactory chamber" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "olfactory chamber cavity" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "olfactory pit" RELATED INCONSISTENT [ZFA:0000130] xref: AAO:0000314 xref: BTO:0002096 xref: EHDAA2:0001226 xref: EHDAA:6801 xref: EMAPA:17604 xref: FMA:54378 xref: GAID:350 xref: MA:0000284 xref: MESH:D009296 xref: NCIT:C12424 xref: SCTID:263481003 xref: TAO:0000130 xref: UMLS:C0027423 {source="ncithesaurus:Nasal_Cavity"} xref: VHOG:0000271 xref: Wikipedia:Nasal_cavity xref: ZFA:0000130 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity relationship: develops_from UBERON:0005870 ! olfactory pit relationship: part_of UBERON:0015788 {source="cjm"} ! olfactory apparatus chamber property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI property_value: editor_note "define the boundaries of this cavity for a variety of species and check that parthood relations are not too strong." xsd:string property_value: UBPROP:0000001 "a large air filled space above and behind the nose in the middle of the face[WP][Wikipedia:Nasal_cavity]." xsd:string {source="Wikipedia:Nasal_cavity"} property_value: UBPROP:0000001 "Saclike space internal to the nasal capsule lined by respiratory and sensory epithelium and glandular tissue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000314", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "Despite significant modification to the nasal cavity within Archosauria and its extreme hypertrophy and supraorbital development in Lambeosaurinae, the neural olfactory system and the olfactory region of the nasal cavity proper retain their plesiomorphic positions and associations, suggesting that this system is highly conserved in vertebrate evolution.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000271", ontology="VHOG", source="DOI:10.1666/0094-8373(2006)032[0109:NCHACC]2.0.CO;2 Evans DC, Nasal cavity homologies and cranial crest function in lambeosaurine dinosaurs. Paleobiology (2006)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "in humans, the cavity includes and starts at the nares and reaches all the way through to the and includes the choanae, the posterior nasal apertures" xsd:string {source="HP"} [Term] id: UBERON:0001708 name: jaw skeleton namespace: uberon def: "Subdivision of skeleton which includes upper and lower jaw skeletons." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Jaw] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior splanchnocranium" RELATED [] synonym: "jaw" EXACT [MA:0001905] synonym: "jaw cartilage" EXACT [ZFA:0001227] synonym: "jaws" RELATED [] synonym: "mandibular arch" RELATED [TAO:0001227] synonym: "mandibular arch skeleton" EXACT [ZFA:0001227] synonym: "oral jaw skeleton" RELATED [] synonym: "pharyngeal arch 1 skeleton" RELATED [] synonym: "visceral arch 1" RELATED [] xref: AAO:0000988 xref: BTO:0001749 xref: EMAPA:35455 xref: FMA:54396 xref: GAID:214 xref: galen:Jaw xref: MA:0001905 xref: MESH:D007568 xref: NCIT:C48821 xref: SCTID:181811001 xref: TAO:0001227 xref: UMLS:C0022359 {source="ncithesaurus:Jaw"} xref: Wikipedia:Jaw xref: ZFA:0001227 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0011595 ! jaw region relationship: capable_of NBO:0000073 ! chewing relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: overlaps UBERON:0008895 ! splanchnocranium relationship: part_of UBERON:0011156 {source="cjm"} ! facial skeleton relationship: part_of UBERON:0011595 ! jaw region relationship: skeleton_of UBERON:0011595 ! jaw region property_value: editor_note "TODO - move ZFA:0001227 (it is the entire jaw skeleton)." xsd:string property_value: UBPROP:0000001 "Skeletal and cartilage elements of the first pharyngeal arch.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001227", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000011 "There are cellular contributions from all three embryonic germ layers: pharyngeal mesoderm, endoderm and neural crest that migrates out of the ectoderm (Noden, 1983)." xsd:string property_value: UBPROP:0000012 "in FMA, the jaw is an organism subdivision cluster, and includes mucosal tissue such as the gingiva as parts. It appears to be skeletal in MA (and has teeth as parts). It is reasonable to assume that ZFA and XAO consider the upper and lower jaws to be skeletal elements or clusters. EHDAA2 also considers these clusters. TODO - follow EHDAA2 model. These arbitrary differences in terminology and classification have to be reconciled with the genuine well-known biological differences in the skeletal elements across vertebrates" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001709 name: upper jaw region namespace: uberon def: "Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Upper_jaw] comment: See notes for jaw w.r.t skeletal element vs subdivision of head. subset: uberon_slim subset: vertebrate_core synonym: "alveolodental arch of bimaxilla" RELATED [FMA:59399] synonym: "dorsal mandibular arch" RELATED [] synonym: "dorsal pharyngeal arch 1" RELATED INCONSISTENT [] synonym: "maxillary part of mouth" EXACT [FMA:59399] synonym: "maxillary part of mouth proper" RELATED [FMA:59399] synonym: "palatoquadrate arch" RELATED INCONSISTENT [] synonym: "upper pharyngeal jaws" RELATED [] xref: AAO:0000620 xref: EHDAA2:0002118 xref: EHDAA2:0004607 xref: EHDAA:8025 xref: EMAPA:17924 xref: FMA:59399 xref: ncithesaurus:Upper_Jaw xref: SCTID:362636001 xref: VHOG:0000454 xref: Wikipedia:Upper_jaw is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000475 ! organism subdivision is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0000475 ! organism subdivision intersection_of: has_skeleton UBERON:0003277 ! skeleton of upper jaw disjoint_from: UBERON:0001710 ! lower jaw region relationship: has_skeleton UBERON:0003277 ! skeleton of upper jaw relationship: part_of UBERON:0004089 ! midface relationship: part_of UBERON:0011595 ! jaw region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray189.png" xsd:anyURI property_value: RO:0002171 UBERON:0001710 property_value: UBPROP:0000001 "Superior maxillary arch located on the anterior and lateral sides of the skull.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000620", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000454", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "Note isa/partof difference MA/FMA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001710 name: lower jaw region namespace: uberon def: "Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]." [Wikipedia:Lower_jaw] comment: See notes for jaw w.r.t skeletal element vs subdivision of head subset: efo_slim subset: uberon_slim subset: vertebrate_core synonym: "lower part of mouth" RELATED [] synonym: "mandibular part of mouth" EXACT [FMA:59398] synonym: "mandibular series" RELATED [] xref: AAO:0000272 xref: EFO:0003660 xref: EHDAA2:0001018 xref: EHDAA:7995 xref: EMAPA:17906 xref: FMA:59398 xref: MESH:D008334 xref: ncithesaurus:Lower_Jaw xref: SCTID:362637005 xref: VHOG:0000453 xref: Wikipedia:Lower_jaw is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000475 ! organism subdivision is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0000475 ! organism subdivision intersection_of: has_skeleton UBERON:0003278 ! skeleton of lower jaw relationship: develops_from UBERON:0005867 {source="Wikipedia:Mandibular_prominence"} ! mandibular prominence relationship: has_skeleton UBERON:0003278 ! skeleton of lower jaw relationship: part_of UBERON:0011595 ! jaw region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png" xsd:anyURI property_value: RO:0002171 UBERON:0001709 property_value: UBPROP:0000001 "Inferior mandibular arch located on the anterior and lateral sides of the skull.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000272", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000453", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "Note isa/partof difference MA/FMA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001714 name: cranial ganglion namespace: uberon alt_id: UBERON:0003213 alt_id: UBERON:0026601 def: "The groups of nerve cell bodies associated with the twelve cranial nerves." [ISBN:0-683-40008-8, MGI:csmith, MP:0001081, PMID:9362461] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cranial ganglia" RELATED [] synonym: "cranial ganglion" EXACT [] synonym: "cranial ganglion part of peripheral nervous system" EXACT [BIRNLEX:2597] synonym: "cranial ganglion/nerve" EXACT [] synonym: "cranial nerve ganglion" EXACT [] synonym: "cranial neural ganglion" EXACT [] synonym: "cranial neural tree organ ganglion" EXACT [OBOL:automatic] synonym: "ganglion of cranial nerve" EXACT [FMA:54502] synonym: "ganglion of cranial neural tree organ" EXACT [OBOL:automatic] synonym: "head ganglion" RELATED [] synonym: "presumptive cranial ganglia" RELATED [ZFA:0000013] xref: BIRNLEX:2597 xref: BTO:0000106 xref: EFO:0000902 xref: EMAPA:16659 xref: FMA:54502 xref: MA:0000213 xref: MA:0000214 xref: MAT:0000200 xref: MIAA:0000200 xref: SCTID:244448001 xref: TAO:0000013 xref: VHOG:0000076 xref: Wikipedia:Cranial_nerve_ganglion xref: XAO:0000027 xref: ZFA:0000013 is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: extends_fibers_into UBERON:0034713 ! cranial neuron projection bundle relationship: extends_fibers_into UBERON:0034713 ! cranial neuron projection bundle relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000033 ! head property_value: UBPROP:0000001 "Ganglion which is located in the head.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000013", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001716 name: secondary palate namespace: uberon def: "The part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences." [http://www.indiana.edu/~anat550/hnanim/face/face.html, Wikipedia:Secondary_palate] subset: pheno_slim subset: uberon_slim synonym: "definitive palate" EXACT [EMAPA:18948] synonym: "oral roof" EXACT [] synonym: "palate" BROAD SENSU [EMAPA:18948, GO:0060021, MA:0002476] synonym: "palatum" BROAD [] synonym: "palatum" RELATED LATIN [Wikipedia:Palate] synonym: "palatum definitivum" EXACT LATIN [Wikipedia:Secondary_palate] synonym: "palatum secundarium" EXACT LATIN [Wikipedia:Secondary_palate] synonym: "roof of mouth" RELATED [] xref: BTO:0001779 xref: EMAPA:18948 xref: FMA:54549 xref: GAID:152 xref: galen:Palate xref: MA:0002476 xref: MESH:D010159 xref: NCIT:C12229 xref: NCIT:C34292 xref: SCTID:181227004 xref: UMLS:C0700374 {source="ncithesaurus:Palate"} xref: UMLS:C1519217 {source="ncithesaurus:Secondary_Palate"} xref: Wikipedia:Secondary_palate is_a: UBERON:0007375 ! roof of mouth is_a: UBERON:0010313 ! neural crest-derived structure relationship: adjacent_to UBERON:0000167 ! oral cavity relationship: adjacent_to UBERON:0001707 ! nasal cavity relationship: develops_from UBERON:0005619 {notes="fusion", source="http://www.indiana.edu/~anat550/hnanim/face/face.html"} ! secondary palatal shelf relationship: only_in_taxon NCBITaxon:32524 ! Amniota relationship: part_of UBERON:0001709 {source="EMAPA"} ! upper jaw region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/31/Pig_snout_sagittal_cut.jpg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI property_value: UBPROP:0000007 "palatal" xsd:string property_value: UBPROP:0000008 "present in mammals and some reptiles. A similar structure is found in crocodilians, but, in most other tetrapods, the oral and nasal cavities are not truly separate. The secondary palate is formed by bilateral medial extensions of maxillary processes. The extensions (palatine processes) meet at the midline, merging dorsally with nasal septum and rostrally with primary palate. The secondary palate (hard palate) separates nasal and oral cavities. Caudal extension of the secondary palate into the pharynx, forms a soft palate which divides the rostral pharynx into dorsal (nasopharynx) and ventral (oropharynx) chamber." xsd:string property_value: UBPROP:0000009 "separates respiratory and oral passages" xsd:string [Term] id: UBERON:0001723 name: tongue namespace: uberon def: "A muscular organ in the floor of the mouth." [FEED:rd, https://github.com/obophenotype/uberon/issues/256] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "glossus" RELATED [Wikipedia:Tongue] xref: AAO:0010360 xref: BTO:0001385 xref: CALOHA:TS-1050 xref: EFO:0000833 xref: EHDAA2:0002062 xref: EHDAA:9144 xref: EMAPA:17185 xref: EV:0100058 xref: FMA:54640 xref: GAID:816 xref: MA:0000347 xref: MAT:0000040 xref: MESH:D014059 xref: MIAA:0000040 xref: NCIT:C12422 xref: SCTID:181226008 xref: TAO:0005333 xref: UMLS:C0040408 {source="ncithesaurus:Tongue"} xref: VHOG:0000419 xref: Wikipedia:Tongue xref: XAO:0000446 xref: ZFA:0005333 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000020 {source="GO"} ! sense organ is_a: UBERON:0013765 ! digestive system element relationship: adjacent_to UBERON:0000166 ! oral opening relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system relationship: develops_from UBERON:0008814 ! pharyngeal arch system relationship: develops_from UBERON:0010056 ! future tongue relationship: has_developmental_contribution_from UBERON:0006260 {notes="anterior 2/3"} ! lingual swellings relationship: has_developmental_contribution_from UBERON:0006756 {source="Wikipedia"} ! median lingual swelling relationship: has_developmental_contribution_from UBERON:0006757 {source="Wikipedia"} ! lateral lingual swelling relationship: immediate_transformation_of UBERON:0010056 {evidence="definitional"} ! future tongue relationship: part_of UBERON:0000165 {source="BTO", source="EHDAA2", source="FMA", source="ZFA"} ! mouth relationship: part_of UBERON:0001033 {source="MA"} ! gustatory system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a6/Tongue.agr.jpg" xsd:anyURI property_value: editor_note "in MA the tongue is part of the oral region, which in uberon is treated as the oral opening. consider revising oral opening - oral region equivalence." xsd:string property_value: UBPROP:0000001 "A mobile mass of muscular tissue that is covered with mucous membrane, occupies much of the cavity of the mouth, forms part of its floor, bears the organ of taste, and assists in chewing and swallowing. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000419", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/tongue"} property_value: UBPROP:0000001 "Muscular organ in the floor of the mouth.[FEED]" xsd:string {date_retrieved="2012-07-02", ontology="FEED", url="http://www.feedexp.org"} property_value: UBPROP:0000001 "The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech[GO][GO:0043586]." xsd:string {source="GO:0043586"} property_value: UBPROP:0000003 "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000419", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x Iwasaki S, Evolution of the structure and function of the vertebrate tongue. J Anat (2002)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "glossal" xsd:string property_value: UBPROP:0000007 "lingual" xsd:string property_value: UBPROP:0000008 "Many species of fish have small folds at the base of their mouths that might informally be called tongues, but they lack a muscular structure like the true tongues found in most tetrapods" xsd:string property_value: UBPROP:0000011 "The tongue has contributions from all pharyngeal arches which changes with time. The tongue initially begins as swelling rostral to foramen cecum, the median tongue bud.. tongue muscles derive from the somites - http://php.med.unsw.edu.au/embryology/index.php?title=Tongue_Development#Pharyngeal_Arch_Contributions" xsd:string [Term] id: UBERON:0001725 name: cranial synchondrosis namespace: uberon def: "The cartilaginous joints of the skull; these include sphenoethmoidal synchondrosis, sphenooccipital synchondrosis, sphenopetrosal synchondrosis, petrooccipital synchondrosis, anterior intraoccipital synchondrosis and posterior intraoccipital synchondrosis." [http://www.medilexicon.com/medicaldictionary.php?t=87514] xref: EMAPA:35264 xref: FMA:54816 xref: MA:0001502 xref: SCTID:314228003 is_a: UBERON:0002215 {source="FMA"} ! synchondrosis intersection_of: UBERON:0002215 ! synchondrosis intersection_of: part_of UBERON:0003129 ! skull relationship: part_of UBERON:0003129 ! skull [Term] id: UBERON:0001726 name: papilla of tongue namespace: uberon subset: pheno_slim synonym: "lingual papilla" EXACT [] synonym: "tongue papilla" EXACT [] xref: BIRNLEX:4102 xref: EMAPA:32777 xref: FMA:54819 xref: MA:0001593 xref: NCIT:C33258 xref: SCTID:368728006 xref: UMLS:C0226964 {source="ncithesaurus:Papilla_of_the_Tongue", source="BIRNLEX:4102"} xref: UMLS:C1289183 {source="BIRNLEX:4102"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0005020 ! mucosa of tongue relationship: part_of UBERON:0009471 {source="FMA-modified"} ! dorsum of tongue [Term] id: UBERON:0001727 name: taste bud namespace: uberon def: "A specialized receptor organ that is a collection of cells spanning the gustatory epithelium." [http://periowiki.wikispot.org/Taste_bud_histology] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "caliculus gustatorius" RELATED PLURAL [Wikipedia:Taste_bud] synonym: "taste buds" RELATED PLURAL [Wikipedia:Taste_bud] synonym: "taste-bud" RELATED [Wikipedia:Taste_bud] synonym: "tastebud" EXACT [Wikipedia:Taste_bud] synonym: "tastebuds" RELATED PLURAL [Wikipedia:Taste_bud] xref: AAO:0010573 xref: BIRNLEX:4101 xref: BTO:0000989 xref: CALOHA:TS-1015 xref: EMAPA:35850 xref: FMA:54825 xref: GAID:815 xref: http://uri.neuinfo.org/nif/nifstd/nifext_14 xref: MA:0001591 xref: MESH:D013650 xref: NCIT:C96518 xref: SCTID:362099006 xref: TAO:0001074 xref: UMLS:C0039337 {source="ncithesaurus:Taste_Bud", source="BIRNLEX:4101"} xref: VHOG:0000130 xref: Wikipedia:Taste_bud xref: XAO:0000445 xref: ZFA:0001074 is_a: UBERON:0003212 ! gustatory organ is_a: UBERON:0004119 ! endoderm-derived structure relationship: capable_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste relationship: contributes_to_morphology_of UBERON:0001033 ! gustatory system relationship: develops_from UBERON:0007690 {source="http://dev.biologists.org/content/128/22/4573.full"} ! early pharyngeal endoderm relationship: has_part CL:0000209 {source="FMA"} ! taste receptor cell relationship: part_of UBERON:0002926 {source="NIF"} ! gustatory epithelium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5a/Gray1018.png" xsd:anyURI property_value: RO:0002171 UBERON:0002467 {source="http://periowiki.wikispot.org/Taste_bud_histology"} property_value: UBPROP:0000001 "A chemoreceptive organ.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010573", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "One of a number of receptor cell nests located in the epithelium of the papillae of the tongue and in the soft palate, epiglottis, and pharynx that mediate the sense of taste. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000130", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/taste+bud"} property_value: UBPROP:0000003 "Experients in amphibia have shown that an intrinsic feature of the pharyngeal endoderm is its ability to generate taste buds and this capacity must have been acquired by the endoderm at the origin of the vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000130", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In humans, saste buds may be found on the tongue, soft palatte, epiglottis and upper pharynx. In other species they may be found in more unusual places, such as the trunk, or on the barbels or fins of fish." xsd:string property_value: UBPROP:0000011 "arise by inductive interactions between epithelial cells and invading gustatory cells from chorda tympani (facial), glossophrayngeal and vagues nerves ISBN:1607950324 (todo - request cell terms from CL)" xsd:string [Term] id: UBERON:0001728 name: nasopharynx namespace: uberon def: "The section of the pharynx that lies above the soft palate." [MGI:cwg, MP:0002251] subset: pheno_slim subset: uberon_slim synonym: "epipharynx" RELATED [Wikipedia:Pharynx] synonym: "nasal part of pharynx" EXACT [] synonym: "Nasenrachenraum" RELATED [BTO:0000662] synonym: "pars nasalis pharyngis" RELATED LATIN [Wikipedia:Nasopharynx] synonym: "rhinopharynx" EXACT [] xref: BTO:0000662 xref: CALOHA:TS-0663 xref: EHDAA2:0001239 xref: EHDAA:7086 xref: EMAPA:17670 xref: EV:0100066 xref: FMA:54878 xref: GAID:339 xref: MA:0000443 xref: MAT:0000447 xref: MESH:D009305 xref: NCIT:C12423 xref: SCTID:181200003 xref: UMLS:C0027442 {source="ncithesaurus:Nasopharynx"} xref: VHOG:0000375 xref: Wikipedia:Nasopharynx is_a: UBERON:0000072 ! proximo-distal subdivision of respiratory tract relationship: contributes_to_morphology_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001557 ! upper respiratory tract property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/4a/Illu_pharynx.jpg" xsd:anyURI property_value: UBPROP:0000001 "The uppermost of the three regions of the throat (pharynx), situated behind the nasal cavity and extending from the posterior nares to the level above the soft palate. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000375", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/nasopharynx"} property_value: UBPROP:0000007 "nasopharyngeal" xsd:string property_value: UBPROP:0000008 "In humans - in front it communicates through the choanae with the nasal cavities. On its lateral wall is the pharyngeal ostium of the auditory tube, somewhat triangular in shape, and bounded behind by a firm prominence, the torus tubarius or cushion, caused by the medial end of the cartilage of the tube which elevates the mucous membrane" xsd:string [Term] id: UBERON:0001731 name: cavity of pharynx namespace: uberon def: "An anatomical space that is enclosed by a pharynx." [OBOL:automatic] synonym: "cavitas pharyngealis" RELATED LATIN [] synonym: "cavitas pharyngis" RELATED [BTO:0002097] synonym: "lumen of pharynx" EXACT [] synonym: "pharyngeal cavity" EXACT [] xref: AAO:0010435 xref: BSA:0000113 xref: BTO:0002097 xref: EMAPA:18381 xref: FMA:54935 xref: SCTID:180543003 xref: XAO:0000105 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0006562 ! pharynx relationship: develops_from UBERON:0001041 {source="XAO"} ! foregut relationship: luminal_space_of UBERON:0006562 ! pharynx relationship: part_of UBERON:0006562 ! pharynx property_value: UBPROP:0000008 "See notes for pharynx - as a grouping class this is probably too bad. We exclude WBbt:0005790 (pharyngeal lumen) because of the developmental relationship" xsd:string property_value: UBPROP:0000011 "TOODO check" xsd:string [Term] id: UBERON:0001737 name: larynx namespace: uberon def: "A continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Larynx] subset: efo_slim subset: pheno_slim subset: uberon_slim xref: AAO:0000268 xref: BTO:0001208 xref: CALOHA:TS-0532 xref: EFO:0000838 xref: EHDAA2:0004063 xref: EMAPA:18333 xref: EV:0100039 xref: FMA:55097 xref: GAID:108 xref: galen:Larynx xref: MA:0000414 xref: MAT:0000187 xref: MESH:D007830 xref: MIAA:0000187 xref: NCIT:C12420 xref: SCTID:181212004 xref: UMLS:C0023078 {source="ncithesaurus:Larynx"} xref: VHOG:0001279 xref: Wikipedia:Larynx xref: XAO:0003081 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000072 ! proximo-distal subdivision of respiratory tract relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium relationship: innervated_by UBERON:0003716 ! recurrent laryngeal nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8a/Larynx_external_en.svg" xsd:anyURI property_value: UBPROP:0000001 "An anatomical cluster consisting of the epiglottus, the arytenoid cartilages, the thyroid cartilage, the cricoid cartilage and the muscles, membranes, and ligaments connecting them, and also of the mucosal covering these structures.[FEED]" xsd:string {date_retrieved="2012-07-02", ontology="FEED", url="http://www.feedexp.org"} property_value: UBPROP:0000001 "Anatomical structure consisting of a narrowly triangular chamber supported by a series of semicircular cartilages in which part of the sound-production system is located.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000268", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "(In anura) a dorsal pair of arytenoid cartilages (...), which support vocal cords, and a ventral pair (often fused) of cricoid cartilage (...). These cartilages are regarded as derivatives of posterior visceral arches of ancestors. Together they constitute the larynx, a structure characteristic of tetrapods. (...) (In mammals) Paired arytenoid cartilages help support and control the vocal cords. The cricoid cartilage is single. Two additional cartilages are present that are lacking in other vertebrates: a large ventral thyroid cartilage (...) and a cartilage in the epiglottis.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001279", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.239-241", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "laryngeal" xsd:string [Term] id: UBERON:0001739 name: laryngeal cartilage namespace: uberon def: "The cartilaginous structures that support the larynx." [MP:0002256] subset: pheno_slim synonym: "cartilage of larynx" EXACT [FMA:55108] synonym: "cartilagines laryngeales" EXACT PLURAL [] synonym: "larynx cartilage" EXACT [VHOG:0001550] xref: BTO:0003660 xref: EHDAA:8157 xref: EMAPA:18697 xref: FMA:55108 xref: GAID:107 xref: MA:0001758 xref: MESH:D007817 xref: NCIT:C12281 xref: SCTID:263482005 xref: UMLS:C0023050 {source="ncithesaurus:Laryngeal_Cartilage"} xref: VHOG:0001550 is_a: UBERON:0003406 ! cartilage of respiratory system is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0011004 ! pharyngeal arch cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0001737 ! larynx relationship: develops_from UBERON:0010213 ! laryngeal pre-cartilage condensation relationship: part_of UBERON:0010212 ! laryngeal apparatus property_value: UBPROP:0000003 "(In anura) a dorsal pair of arytenoid cartilages (...), which support vocal cords, and a ventral pair (often fused) of cricoid cartilage (...). These cartilages are regarded as derivatives of posterior visceral arches of ancestors. Together they constitute the larynx, a structure characteristic of tetrapods. (...) (In mammals) Paired arytenoid cartilages help support and control the vocal cords. The cricoid cartilage is single. Two additional cartilages are present that are lacking in other vertebrates: a large ventral thyroid cartilage (...) and a cartilage in the epiglottis.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001550", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.239-241", source="http://bgee.unil.ch/"} property_value: UBPROP:0000202 FMA:64159 [Term] id: UBERON:0001743 name: ligament of larynx namespace: uberon def: "A ligament that is part of a larynx and connexts the cartilages of the larynx." [http://education.yahoo.com/reference/gray/subjects/subject/236] synonym: "laryngeal ligament" EXACT [] synonym: "larynx ligament" EXACT [MA:0001755] xref: EMAPA:37626 {source="MA:th"} xref: FMA:55131 xref: MA:0001755 xref: NCIT:C32933 xref: SCTID:279508004 xref: UMLS:C0458519 {source="ncithesaurus:Laryngeal_Ligament"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0008845 {source="FMA"} ! nonskeletal ligament intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001737 ! larynx [Term] id: UBERON:0001751 name: dentine namespace: uberon def: "Collagen-rich odontogenic tissue characteristic of teeth and tooth-like skeletal elements (e.g., odontodes); mature dentine is mineralized and develops from predentine tissue; often (but not always) tubular and acellular." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000069] comment: . subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "dentin" EXACT [MA:0002542, ZFA:0005143] synonym: "dentine of tooth" EXACT [] synonym: "predentin" NARROW [GO:0070468] xref: BTO:0003453 xref: EMAPA:35281 xref: FMA:55628 xref: GAID:1272 xref: MA:0002542 xref: MESH:D003804 xref: NCIT:C32453 xref: SCTID:362112004 xref: TAO:0005143 xref: UMLS:C0011429 {source="ncithesaurus:Dentin"} xref: VHOG:0001589 xref: VSAO:0000069 xref: Wikipedia:Dentin xref: XAO:0004051 xref: ZFA:0005143 is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue is_a: UBERON:4000013 ! mineralized skeletal tissue relationship: develops_from UBERON:0011587 ! pre-dentine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: transformation_of UBERON:0011587 {source="VSAO"} ! pre-dentine property_value: UBPROP:0000001 "Mineralized collagen containing substance that forms the tooth structure.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005143", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Dentine is a bona fide vertebrate novelty, and dentine-secreting odontoblasts represent a cell type that is exclusively derived from the neural crest.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001589", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2012.01495.x Hall BK, Gillis JA, Incremental evolution of the neural crest, neural crest cells and neural crest-derived skeletal tissues. J Anat (2012)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "dentinal" xsd:string property_value: UBPROP:0000008 "Dentine is found in the fossil record as early as the late Cambrian, in fish, where it may have had a role in electrochemical sensing of the environment as well as assisting in defense[WP]" xsd:string [Term] id: UBERON:0001752 name: enamel namespace: uberon def: "A dentine-like hypermineralized substance that covers the tooth tip. Enamel's primary mineral is hydroxylapatite, which is a crystalline calcium phosphate. Unlike dentin and bone, enamel does not contain collagen. Instead, it has two unique classes of proteins called amelogenins and enamelins[WP]." [Wikipedia:Enamel_organ, ZFIN:curator] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "enamel of tooth" EXACT [] synonym: "enamel tissue" EXACT [VSAO:curator] synonym: "enameloid" RELATED [] synonym: "tooth enamel" EXACT [] xref: BTO:0001844 xref: CALOHA:TS-1057 xref: EMAPA:35303 xref: FMA:55629 xref: MA:0002543 xref: MESH:D003743 xref: NCIT:C32505 xref: SCTID:362113009 xref: UMLS:C0011350 {source="ncithesaurus:Enamel"} xref: VSAO:0000065 xref: Wikipedia:Enamel_organ xref: XAO:0004198 is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue is_a: UBERON:4000013 ! mineralized skeletal tissue relationship: composed_primarily_of CHEBI:52255 {proportion="85", source="Wikipedia:ENAM"} ! hydroxylapatite relationship: develops_from UBERON:0011588 {source="VSAO"} ! pre-enamel relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Enamelorgan11-17-05.jpg" xsd:anyURI property_value: editor_note "current classification under substance of tooth may be turned into taxon GCI (e.g. sharks have enamel in dermal denticles)" xsd:string property_value: RO:0002161 NCBITaxon:9359 {source="PMID:19730686"} property_value: RO:0002161 NCBITaxon:9816 {source="PMID:19730686"} property_value: UBPROP:0000001 "Skeletal tissue that consists of an avascular, noncollagenous, hypermineralized matrix that is deposited by ameloblasts that are excluded from the matrix. Enamel develops from organic pre-enamel tissue that is replaced by a largely inorganic matrix.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000065", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000012 "part_of tooth enamel organ in MA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001754 name: dental pulp namespace: uberon def: "The part in the center of a tooth made up of living soft tissue and cells called odontoblasts[WP]." [Wikipedia:Dental_pulp] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "dental pulp cell" RELATED [BTO:0000339] synonym: "pulp of tooth" EXACT [] synonym: "tooth pulp" EXACT [ZFA:0005141] xref: BTO:0000339 xref: CALOHA:TS-0195 xref: EMAPA:35274 xref: FMA:55631 xref: GAID:1270 xref: MA:0001599 xref: MESH:D003782 xref: NCIT:C32451 xref: SCTID:362110007 xref: TAO:0005141 xref: UMLS:C0011399 {source="ncithesaurus:Dental_Pulp"} xref: VHOG:0001469 xref: Wikipedia:Dental_pulp xref: ZFA:0005141 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0011825 {source="FMA"} ! loose connective tissue relationship: develops_from UBERON:0001763 {source="ZFA"} ! odontogenic papilla relationship: has_part CL:0000060 ! odontoblast relationship: part_of UBERON:0001091 ! calcareous tooth property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/2/2e/Tooth_Section.svg" xsd:anyURI property_value: UBPROP:0000001 "Material in the center of the dentine of the mature tooth. In secondary teeth the pulp contains blood vessels and odontoblast.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005141", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The oral cavity of vertebrates is generally thought to arise as an ectodermal invagination. Consistent with this, oral teeth are proposed to arise exclusively from ectoderm, contributing to tooth enamel epithelium, and from neural crest derived mesenchyme, contributing to dentin and pulp (reference 1); Teeth and tooth-like structures, together named odontodes, are repeated organs thought to share a common evolutionary origin. These structures can be found in gnathostomes at different locations along the body: oral teeth in the jaws, teeth and denticles in the oral-pharyngeal cavity, and dermal denticles on elasmobranch skin (reference 2).[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001469", ontology="VHOG", source="DOI:10.1038/nature07304 Soukup V, Epperlein HH, Horacek I, Cerny R, Dual epithelial origin of vertebrate oral teeth. Nature (2008), DOI:10.1186/1471-2148-11-307 The homology of odontodes in gnathostomes: insights from Dlx gene expression in the dogfish, Scyliorhinus canicula. BMC Evolutionary Biology (2011)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001756 name: middle ear namespace: uberon def: "The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window)[GO]." [GO:0042474, Wikipedia:Middle_ear] subset: pheno_slim subset: uberon_slim synonym: "auris media" RELATED LATIN [BTO:0002099, Wikipedia:Middle_ear] xref: AAO:0011065 xref: BIRNLEX:1695 xref: BTO:0002099 xref: CALOHA:TS-2233 xref: EHDAA2:0001181 xref: EHDAA:5693 xref: EMAPA:17000 xref: EV:0100357 xref: FMA:56513 xref: GAID:165 xref: MA:0000253 xref: MAT:0000146 xref: MESH:D004432 xref: MIAA:0000146 xref: NCIT:C12274 xref: SCTID:181185000 xref: UMLS:C0013455 {source="ncithesaurus:Middle_Ear", source="BIRNLEX:1695"} xref: UMLS:C1268972 {source="BIRNLEX:1695"} xref: VHOG:0000312 xref: Wikipedia:Middle_ear xref: XAO:0000191 is_a: UBERON:0034921 ! multi organ part structure relationship: contributes_to_morphology_of UBERON:0001690 ! ear relationship: part_of UBERON:0001690 ! ear property_value: UBPROP:0000001 "The intermediate portion of the ear which consists of a small air-filled and membrane-lined chamber. It is lodged in the temporal bone and continues with the nasopharynx through the Eustachian tube. It is separated from the external ear by the tympanic membrane and from the inner ear by the fenestrae. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000312", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The tympanic cavity and auditory tube of an amniote develop from the first embryonic pharyngeal pouch, so they are homologous to the first gill pouch, or spiracle, of a fish. We are uncertain whether this homology strictly applies to the middle ear cavity and auditory tube of lissamphibians, which show certain peculiarities in their development.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000312", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.417", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001757 name: pinna namespace: uberon def: "The part of the ear that projects from the head, connecting to the external acoustic meatus." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Pinna_(anatomy)] subset: pheno_slim subset: uberon_slim synonym: "auricle" EXACT [] synonym: "auricle of ear" EXACT [] synonym: "auricle of external ear" EXACT [] synonym: "auricula" EXACT [Wikipedia:Auricula] synonym: "auricula (auris externa)" EXACT [] synonym: "pinna of ear" EXACT [] synonym: "pinnae" RELATED PLURAL [] xref: EHDAA2:0001467 xref: EMAPA:17589 xref: EV:0100355 xref: FMA:56580 xref: galen:Auricle xref: MA:0000259 xref: NCIT:C32165 xref: SCTID:421159007 xref: UMLS:C0928075 {source="ncithesaurus:Auricle"} xref: VHOG:0000460 xref: Wikipedia:Pinna_(anatomy) is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001444 ! subdivision of head relationship: continuous_with UBERON:0001352 ! external acoustic meatus relationship: develops_from UBERON:0006208 ! auditory hillocks relationship: has_quality PATO:0001297 ! reflectivity relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0001691 ! external ear property_value: UBPROP:0000001 "The external expanded part of the ear characterized by a funnel-shaped structure through which the sound vibrations are received. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000460", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "Mammals have a third type of tympanic ear. An external flap, the auricle or pinna, helps funnel sound waves down the external acoustic meatus to the tympanic membrane.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000460", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.420", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In various species, the pinna can also signal mood and radiate heat" xsd:string property_value: UBPROP:0000009 "The purpose of the pinna is to collect sound. It does so by acting as a funnel, amplifying the sound and directing it to the ear canal. While reflecting from the pinna, sound also goes through a filtering process which adds directional information to the sound (see sound localization, head-related transfer function, pinna notch)." xsd:string [Term] id: UBERON:0001758 name: periodontium namespace: uberon def: "The tissues that invest or help to invest and support the teeth, including the periodontal ligament, gingivae, cementum, and alveolar and supporting bone[BTO]." [BTO:0001021, Wikipedia:Periodontium] subset: pheno_slim synonym: "paradentium" RELATED [MESH:A14.254.646] synonym: "periodontal ligament" RELATED INCONSISTENT [FMA:56665] synonym: "periodontal membrane" RELATED [MA:0002467] synonym: "tooth supporting structure" RELATED [MESH:A14.254.646] xref: BTO:0001021 xref: CALOHA:TS-2380 xref: GAID:216 xref: MESH:D010519 xref: NCIT:C33304 xref: UMLS:C0031093 {source="ncithesaurus:Periodontium"} xref: Wikipedia:Periodontium is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000479 {source="cjm"} ! tissue relationship: adjacent_to UBERON:0001091 ! calcareous tooth relationship: has_part CL:0002166 {source="FMA"} ! epithelial cell of Malassez relationship: part_of UBERON:0003672 {source="cjm"} ! dentition property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/dc/The_Periodontium.jpg" xsd:anyURI property_value: UBPROP:0000012 "FMA treats periodontium and periodontal ligament as the same" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001759 name: vagus nerve namespace: uberon def: "Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart)." [ISBN:0471209627, Wikipedia:Vagus_nerve] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "10n" BROAD ABBREVIATION [BIRNLEX:801, NIFSTD:NeuroNames_abbrevSource] synonym: "CN-X" RELATED [] synonym: "cranial nerve X" RELATED [] synonym: "nerve X" RELATED [NeuroNames:702] synonym: "nervus vagus" RELATED LATIN [BTO:0003472, Wikipedia:Vagus_nerve] synonym: "nervus vagus [x]" EXACT LATIN [FMA:5731, FMA:TA] synonym: "pneuomgastric nerve" RELATED [BTO:0003472] synonym: "tenth cranial nerve" EXACT [] synonym: "vagal nerve" RELATED [] synonym: "vagus" EXACT [] synonym: "vagus nerve [X]" EXACT [] synonym: "vagus nerve or its root" RELATED [BAMS:10n] synonym: "vagus nerve tree" EXACT [] synonym: "vagus X nerve" EXACT [MA:0001106] xref: AAO:0010475 xref: BAMS:10n xref: BAMS:Xn xref: BIRNLEX:801 xref: BTO:0003472 xref: EFO:0002549 xref: EMAPA:37797 {source="MA:th"} xref: FMA:5731 xref: GAID:721 xref: galen:VagusNerve xref: HBA:9337 xref: MA:0001106 xref: MBA:917 xref: MESH:D014630 xref: NCIT:C12812 xref: neuronames:702 {source="BIRNLEX:801"} xref: SCTID:362466001 xref: TAO:0000453 xref: UMLS:C0042276 {source="ncithesaurus:Vagus_Nerve", source="BIRNLEX:801"} xref: UMLS:C1305910 {source="BIRNLEX:801"} xref: VHOG:0000737 xref: Wikipedia:Vagus_nerve xref: XAO:0003097 xref: ZFA:0000453 is_a: UBERON:0001785 ! cranial nerve is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0001785 ! cranial nerve intersection_of: extends_fibers_into UBERON:0011775 ! vagus nerve nucleus relationship: extends_fibers_into UBERON:0002075 ! viscus relationship: extends_fibers_into UBERON:0011775 ! vagus nerve nucleus relationship: has_developmental_contribution_from UBERON:0005239 {notes="motor", source="Wikipedia"} ! basal plate metencephalon relationship: part_of UBERON:0001033 ! gustatory system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Nerve consisting of branchiomotor and visceral efferent fibers which branch and innervate the smooth muscles and glands of the heart, lungs, esophagus, and stomach as well as some throat muscles. Sensory fibers supply mucosa of the mouth and pharynx.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010475", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...) (reference 1); Phylogenetically, the cranial nerves are thought to have evolved from dorsal and ventral nerves of a few anterior spinal nerves that became incorporated into the braincase. Dorsal and ventral nerves fuse in the trunk but not in the head, and they produce two series: dorsal cranial nerves (V, VII, IX, and X) and ventral cranial nerves (III, IV, VI, and XIII) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000737", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.625", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001763 name: odontogenic papilla namespace: uberon def: "A condensation of odontoblasts that forms the part of a tooth germ that gives rise to dentin and pulp in the mature tooth. It lies below a cellular aggregation known as the enamel organ." [Wikipedia:Dental_papilla, ZFA:0005140] subset: uberon_slim subset: vertebrate_core synonym: "dental papilla" RELATED [MA:0001598] synonym: "dentinal papilla" RELATED [BTO:0001839] synonym: "dermal papilla" RELATED INCONSISTENT [ISBN:0073040584] synonym: "odontogenic condensation" EXACT [VSAO:0000025] synonym: "papilla dentis" RELATED LATIN [Wikipedia:Dental_papilla] synonym: "pharyngeal tooth mesenchyme" NARROW SENSU [ZFA:0005140] synonym: "tooth mesenchyme" RELATED [ZFA:0005140] xref: BTO:0001839 xref: EMAPA:32892 xref: FMA:57662 xref: GAID:1277 xref: MA:0001598 xref: MESH:D003771 xref: TAO:0005140 xref: VHOG:0001465 xref: VSAO:0000025 xref: Wikipedia:Dental_papilla xref: XAO:0004045 xref: ZFA:0005140 is_a: UBERON:0005856 ! developing mesenchymal condensation is_a: UBERON:0007213 ! mesenchyme derived from head neural crest intersection_of: UBERON:0005856 ! developing mesenchymal condensation intersection_of: composed_primarily_of CL:0007003 ! preodontoblast intersection_of: part_of UBERON:0008281 ! tooth bud relationship: composed_primarily_of CL:0007003 ! preodontoblast relationship: develops_from UBERON:0003856 {source="ZFA"} ! uncondensed odontogenic mesenchyme relationship: immediately_deep_to UBERON:0005176 ! tooth enamel organ relationship: located_in UBERON:0001828 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA-implied"} ! gingiva relationship: part_of UBERON:0008281 ! tooth bud property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/22/Gray1011.png" xsd:anyURI property_value: UBPROP:0000001 "Cell condensation that is a well-defined population of densely organized mesenchymal cells that aggregates adjacent to an epithelium.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000025", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Tissue of the developing tooth. It is composed of pre-odontoblast and undiffentiated mesnchyme cells and connects to the basal lamina.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005140", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Teeth and tooth-like structures, together named odontodes, are repeated organs thought to share a common evolutionary origin. These structures can be found in gnathostomes at different locations along the body: oral teeth in the jaws, teeth and denticles in the oral-pharyngeal cavity, and dermal denticles on elasmobranch skin.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001465", ontology="VHOG", source="DOI:10.1186/1471-2148-11-307 The homology of odontodes in gnathostomes: insights from Dlx gene expression in the dogfish, Scyliorhinus canicula. BMC Evolutionary Biology (2011)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "In humans, the dental papilla appears after 8-10 weeks intra uteral life" xsd:string [Term] id: UBERON:0001766 name: anterior chamber of eyeball namespace: uberon def: "The space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens." [MESH:A09.371.060.067, MP:0005205] subset: pheno_slim synonym: "anterior chamber" EXACT [HP:0000593, MP:0010709] synonym: "anterior chamber of eye" EXACT [] synonym: "camera anterior" EXACT [] synonym: "camera anterior bulbi" RELATED [BTO:0002084] synonym: "camera anterior bulbi oculi" RELATED LATIN [Wikipedia:Anterior_chamber_of_eyeball] synonym: "camera oculi anterior" RELATED [BTO:0002084] synonym: "eye anterior chamber" EXACT [] xref: BTO:0002084 xref: EHDAA2:0000129 xref: EHDAA:9033 xref: EMAPA:18231 xref: FMA:58078 xref: GAID:889 xref: MA:0000262 xref: MESH:D000867 xref: NCIT:C12667 xref: SCTID:181160009 xref: UMLS:C0003151 {source="ncithesaurus:Anterior_Chamber_of_the_Eye"} xref: VHOG:0001431 xref: Wikipedia:Anterior_chamber_of_eyeball is_a: UBERON:0006311 {source="FMA"} ! chamber of eyeball relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball relationship: part_of UBERON:0001801 ! anterior segment of eyeball property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI property_value: UBPROP:0000001 "The part of the eyeball between the cornea and the iris, filled with aqueous humor. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001431", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/anterior+chamber"} property_value: UBPROP:0000012 "space in EHDAA2 - consider adding Cavity of anterior chamber of eyeball" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0001768 name: uvea namespace: uberon def: "The pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]." [MP:0005197, Wikipedia:Uvea] subset: pheno_slim subset: uberon_slim synonym: "pars iridica retinae" RELATED [Wikipedia:Uvea] synonym: "tunica vasculatis oculi" RELATED [Wikipedia:Uvea] synonym: "tunica vasculosa bulbi" RELATED LATIN [Wikipedia:Uvea] synonym: "tunica vasculosa of eyeball" EXACT [FMA:58103] synonym: "uvea" EXACT [FMA:58103] synonym: "uveal tract" EXACT [FMA:58103] synonym: "vascular layer of eyeball" RELATED [FMA:58103] xref: CALOHA:TS-2228 xref: EMAPA:35901 xref: FMA:58103 xref: GAID:912 xref: MA:0002480 xref: MESH:D014602 xref: NCIT:C12811 xref: SCTID:280648000 xref: UMLS:C0042160 {source="ncithesaurus:Uvea"} xref: Wikipedia:Uvea is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004923 {source="FMA"} ! organ component layer is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye relationship: has_part UBERON:0001769 ! iris relationship: has_part UBERON:0001775 ! ciliary body relationship: has_part UBERON:0001776 ! optic choroid relationship: part_of UBERON:0001801 ! anterior segment of eyeball property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/eb/Gray869.png" xsd:anyURI property_value: editor_note "TODO - check child terms, isa vs partof. See also MA:0001284 ! tunica vasculosa plexus" xsd:string property_value: RO:0002175 NCBITaxon:7955 {source="DOI:10.1177/0192623311409597"} property_value: UBPROP:0000007 "uveal" xsd:string [Term] id: UBERON:0001769 name: iris namespace: uberon def: "The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye." [ISBN:0-683-40008-8, MP:0001322] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior uvea" RELATED [] synonym: "irides" RELATED PLURAL [] synonym: "irises" RELATED PLURAL [VHOG:0000101] xref: AAO:0010347 xref: BTO:0000653 xref: CALOHA:TS-0491 xref: EFO:0004245 xref: EMAPA:19154 xref: EV:0100345 xref: FMA:58235 xref: GAID:917 xref: MA:0000273 xref: MESH:D007498 xref: NCIT:C12737 xref: SCTID:181164000 xref: TAO:0001238 xref: UMLS:C0022077 {source="ncithesaurus:Iris"} xref: VHOG:0000101 xref: Wikipedia:Iris_(anatomy) xref: XAO:0000185 xref: ZFA:0001238 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: contributes_to_morphology_of UBERON:0011892 ! anterior uvea relationship: develops_from UBERON:0004128 {source="XAO"} ! optic vesicle relationship: part_of UBERON:0011892 ! anterior uvea property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The opaque muscular contractile diaphragm suspended in the aqueous humour in front of the lens of the eye. The organ is perforated by the pupil and continues peripherally with the ciliary body. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000101", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000101", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "iridial" xsd:string property_value: UBPROP:0000008 "The avian iris and ciliary body undergoes a transition from smooth-to-striated muscle during embryonic development [DOI:dx.doi.org/10.1006/dbio.1998.9019]" xsd:string [Term] id: UBERON:0001772 name: corneal epithelium namespace: uberon def: "The smooth stratified squamous epithelium that covers the outer surface of the cornea." [MESH:A09.371.060.217.325, MGI:smb, MP:0006000] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior corneal epithelium" EXACT [] synonym: "anterior endothelium of cornea" RELATED [BTO:0000287] synonym: "cornea epithelial tissue" EXACT [OBOL:automatic] synonym: "cornea epithelium" EXACT [OBOL:automatic] synonym: "e. anterius corneae" RELATED LATIN [Wikipedia:Corneal_epithelium] synonym: "endothelium anterius corneae" RELATED [BTO:0000287] synonym: "endothelium camerae anterioris bulbi" RELATED [BTO:0000287] synonym: "endothelium corneale" RELATED [BTO:0000287] synonym: "epithelial tissue of cornea" EXACT [OBOL:automatic] synonym: "epithelium anterius (cornea)" EXACT [] synonym: "epithelium anterius corneae" EXACT LATIN [FMA:58263, FMA:TA] synonym: "epithelium corneæ anterior layer" EXACT [] synonym: "epithelium of cornea" EXACT [] synonym: "epithelium posterius corneae" RELATED [BTO:0000287] synonym: "external epithelium of cornea" EXACT [] xref: BTO:0000287 xref: CALOHA:TS-0173 xref: EFO:0001917 xref: EHDAA2:0000319 xref: EMAPA:17162 xref: FMA:58263 xref: GAID:895 xref: MA:0001243 xref: MESH:D019573 xref: NCIT:C12928 xref: SCTID:368825001 xref: TAO:0002187 xref: UMLS:C0459875 {source="ncithesaurus:Corneal_Epithelium"} xref: Wikipedia:Corneal_epithelium xref: ZFA:0001683 is_a: UBERON:0000488 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! atypical epithelium is_a: UBERON:0010304 {gci_relation="part_of", gci_filler="NCBITaxon:7955"} ! non-keratinized stratified squamous epithelium is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: bounding_layer_of UBERON:0000964 ! cornea relationship: bounding_layer_of UBERON:0000964 ! cornea relationship: contributes_to_morphology_of UBERON:0000964 ! cornea relationship: develops_from UBERON:0000076 {source="ISBN:0781772214"} ! external ectoderm relationship: part_of UBERON:0000964 ! cornea property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Portion of tissue comprised of four to six layers of nonkeratinized, stratified squamous cells and represents approximately 60% of the thickness of the cornea.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002187", ontology="TAO", source="ZFIN:ZDB-PUB-061010-3"} property_value: UBPROP:0000008 "In Humans: It consists of several layers of cells. The cells of the deepest layer are columnar; then follow two or three layers of polyhedral cells, the majority of which are prickle cells similar to those found in the stratum mucosum of the cuticle. Lastly, there are three or four layers of squamous cells, with flattened nuclei" xsd:string property_value: UBPROP:0000008 "In zebrafish: nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman's membrane in mammals" xsd:string [Term] id: UBERON:0001773 name: sclera namespace: uberon def: "Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]." [Wikipedia:Sclera, ZFIN:ZDB-PUB-050701-15] comment: Disease notes: implicated in rheumatoid arthritis. subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "scleral capsule" RELATED [] xref: AAO:0010354 xref: BTO:0001606 xref: EMAPA:19027 xref: EV:0100342 xref: FMA:58269 xref: GAID:911 xref: MA:0000280 xref: MESH:D012590 xref: NCIT:C12784 xref: SCTID:181163006 xref: UMLS:C0036410 {source="ncithesaurus:Sclera"} xref: VHOG:0001274 xref: Wikipedia:Sclera xref: XAO:0000183 xref: ZFA:0005563 is_a: UBERON:0000064 ! organ part is_a: UBERON:0010313 ! neural crest-derived structure relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye relationship: develops_from UBERON:0003314 {source="ISBN:0781772214"} ! eye mesenchyme relationship: has_part CL:0000347 {source="ZFA"} ! scleral cell relationship: has_quality PATO:0000963 ! opaque relationship: part_of UBERON:0012430 {source="FMA"} ! tunica fibrosa of eyeball property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The sclera, also known as the white part of the eye, is the opaque (usually white, though certain animals, such as horses and lizards, can have black sclera), fibrous, protective, outer layer of the eye containing collagen and elastic fiber. It is derived from the neural crest. In children, it is thinner and shows some of the underlying pigment, appearing slightly blue. In the elderly, however, fatty deposits on the sclera can make it appear slightly yellow. The sclera forms the posterior five sixths of the connective tissue coat of the globe. It is continuous with the dura mater and the cornea, and maintains the shape of the globe, offering resistance to internal and external forces, and provides an attachment for the extraocular muscle insertions. The sclera is perforated by plenty of nerves and vessels passing through the posterior scleral foramen, the hole that is formed by the optic nerve. At the optic disk the outer two-thirds of the sclera continues with the dura mater (outer coat of the brain) via the dural sheath of the optic nerve. The inner third joins with some choroidal tissue to form a plate (lamina cribrosa) across the optic nerve with perforations through which the optic fibers (fasciculi). The thickness of the sclera varies from 1mm at the posterior pole to 0.3 mm just behind the rectus muscle insertions. The sclera's blood vessels are mainly on the surface, and together with the conjunctiva (which lies on top) This is a thin layer covering the sclera. Along with the vessels of the conjunctiva, those of the sclera renders the inflamed eye bright red. [WP,unvetted][Wikipedia:Sclera]." xsd:string {source="Wikipedia:Sclera"} property_value: UBPROP:0000001 "The tough, usually white, outer coat of the eyeball, covering all the posterior surface and continuous anteriorly with the cornea. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001274", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/sclera"} property_value: UBPROP:0000007 "scleral" xsd:string property_value: UBPROP:0000008 "in fish, reptiles and monotremes the connective tissue of the sclera is skeletal" xsd:string property_value: UBPROP:0000010 "continuous with the dura mater and the cornea; The sclera forms the posterior five-sixths of the connective tissue coat of the globe." xsd:string property_value: UBPROP:0000011 "Majority derives from NC that surrounds optic cup of neurectoderm; a small temporal portion develops from the mesoderm that contributes to striated extra-ocular muscles and vascular endothelia[Rada&Johnson]." xsd:string property_value: UBPROP:0000011 "Seko et al demonstrate chondrogenic potential and identify this as connective tissue[DOI:10.1371/journal.pone.0003709]." xsd:string [Term] id: UBERON:0001774 name: skeletal muscle of trunk namespace: uberon def: "A skeletal muscle organ that is part of the trunk region." [http://orcid.org/0000-0002-6601-2165] subset: uberon_slim subset: vertebrate_core synonym: "body musculature" EXACT [ZFA:0000473] synonym: "muscle of trunk" EXACT [FMA:58274] synonym: "muscle organ of torso" EXACT [OBOL:automatic] synonym: "muscle organ of trunk" EXACT [OBOL:automatic] synonym: "torso muscle organ" EXACT [OBOL:automatic] synonym: "trunk muscle" EXACT [] synonym: "trunk muscle organ" EXACT [OBOL:automatic] synonym: "trunk musculature" EXACT [] xref: AAO:0000611 xref: EMAPA:35888 xref: FMA:58274 xref: MA:0000514 xref: TAO:0000473 xref: XAO:0003230 xref: ZFA:0000473 is_a: UBERON:0005177 ! trunk region element is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0004479 {source="prolog"} ! musculature of trunk property_value: editor_note "Note that this class excludes smooth muscle elements in the trunk region, such as the internal anal sphincter. This appears to be consistent with other ontologies such as FMA and ZFA which appear to only include skeletal muscles here. In fact the MA class 'trunk muscle' is classified as a 'set of skeletal muscles'." xsd:string property_value: UBPROP:0000012 "Many ontologies do not appear to have a coherent distinction between an individual muscle and the musculature (i.e. the set of muscles in a region), so we group all together here." xsd:string [Term] id: UBERON:0001775 name: ciliary body namespace: uberon def: "The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes." [ISBN:0-683-40008-8, MP:0005099, Wikipedia:Ciliary_body] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior uvea" RELATED [] synonym: "ciliary bodies" RELATED PLURAL [VHOG:0000102] synonym: "corpus ciliare" RELATED LATIN [Wikipedia:Ciliary_body] synonym: "ocular ciliary body" EXACT [] xref: AAO:0010341 xref: BTO:0000260 xref: CALOHA:TS-0694 xref: EMAPA:19065 xref: EV:0100346 xref: FMA:58295 xref: GAID:916 xref: MA:0000264 xref: MESH:D002924 xref: NCIT:C12345 xref: neuronames:1571 xref: SCTID:263340007 xref: UMLS:C0008779 {source="ncithesaurus:Ciliary_Body"} xref: VHOG:0000102 xref: Wikipedia:Ciliary_body xref: XAO:0000186 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: contributes_to_morphology_of UBERON:0011892 ! anterior uvea relationship: develops_from UBERON:0002346 {source="ISBN:0781772214"} ! neurectoderm relationship: has_part UBERON:0001605 ! ciliary muscle relationship: has_part UBERON:0010427 ! ciliary processes relationship: part_of UBERON:0011892 ! anterior uvea property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "The eye of the adult lamprey is remarkably similar to our own, and it possesses numerous features (including the expression of opsin genes) that are very similar to those of the eyes of jawed vertebrates. The lamprey's camera-like eye has a lens, an iris and extra-ocular muscles (five of them, unlike the eyes of jawed vertebrates, which have six), although it lacks intra-ocular muscles. Its retina also has a structure very similar to that of the retinas of other vertebrates, with three nuclear layers comprised of the cell bodies of photoreceptors and bipolar, horizontal, amacrine and ganglion cells. The southern hemisphere lamprey, Geotria australis, possesses five morphological classes of retinal photoreceptor and five classes of opsin, each of which is closely related to the opsins of jawed vertebrates. Given these similarities, we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000102", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001776 name: optic choroid namespace: uberon def: "Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]." [Wikipedia:Choroid] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "chorioid" RELATED [BTO:0001829] synonym: "choroid" EXACT [MA:0000263] synonym: "choroid coat" EXACT [Wikipedia:Choroid] synonym: "choroidea" EXACT [Wikipedia:Choroid] synonym: "choroidea" RELATED LATIN [Wikipedia:Choroid] synonym: "eye choroid" EXACT [VHOG:0001568] synonym: "optic choroid" RELATED [ZFA:0005229] synonym: "posterior uvea" EXACT [Wikipedia:Uvea#Regions] xref: BTO:0001829 xref: CALOHA:TS-2054 xref: EMAPA:19077 xref: EV:0100347 xref: FMA:58298 xref: GAID:913 xref: MA:0000263 xref: MESH:D002829 xref: NCIT:C12344 xref: SCTID:181172003 xref: TAO:0005229 xref: UMLS:C0008520 {source="ncithesaurus:Choroid"} xref: VHOG:0001568 xref: Wikipedia:Choroid xref: ZFA:0005229 is_a: UBERON:0002203 ! vasculature of eye disjoint_from: UBERON:0011892 {source="lexical"} ! anterior uvea relationship: adjacent_to UBERON:0000966 ! retina relationship: adjacent_to UBERON:0001773 ! sclera relationship: adjacent_to UBERON:0011892 ! anterior uvea relationship: contributes_to_morphology_of UBERON:0001768 ! uvea relationship: overlaps UBERON:0001802 {source="Wikipedia"} ! posterior segment of eyeball relationship: part_of UBERON:0001768 {source="MA"} ! uvea relationship: part_of UBERON:0019207 ! chorioretinal region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI property_value: editor_note "check choroid vs choroid layer; check ZFA/TAO placement - no homology assertion in VHOG. Note this is entirely in the posterior region of eyeball in ZFA" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "choroidal" xsd:string property_value: UBPROP:0000012 "MP treats posterior uvea and optic choroid as distinct" xsd:string {external_ontology="MP"} [Term] id: UBERON:0001777 name: substantia propria of cornea namespace: uberon def: "The lamellated connective tissue of the cornea between the Bowman and Descemet membranes." [ISBN:0-683-40008-8, MESH:A09.371.060.217.228, MP:0005300] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "corneal stroma" EXACT [MA:0001245] synonym: "stroma of cornea" EXACT [] synonym: "substantia propria" BROAD [] synonym: "substantia propria corneae" EXACT LATIN [FMA:58306, FMA:TA] xref: CALOHA:TS-1138 xref: EFO:0002514 xref: EMAPA:17602 xref: FMA:58306 xref: GAID:893 xref: MA:0001245 xref: MESH:D003319 xref: NCIT:C12699 xref: SCTID:362511000 xref: TAO:0002189 xref: UMLS:C0010040 {source="ncithesaurus:Corneal_Stroma"} xref: Wikipedia:Corneal_stroma xref: ZFA:0001685 is_a: UBERON:0003891 ! stroma is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0000964 ! cornea relationship: adjacent_to UBERON:0004367 ! Descemet's membrane relationship: adjacent_to UBERON:0004370 ! anterior limiting lamina of cornea relationship: contributes_to_morphology_of UBERON:0000964 ! cornea relationship: develops_from UBERON:0007213 {inferred_by="cjm", source="ISBN:0781772214", source="Wikipedia"} ! mesenchyme derived from head neural crest relationship: part_of UBERON:0000964 ! cornea property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI property_value: UBPROP:0000001 "Portion of tissue that is located basal to Bowman's layer and distal to Descemet's membrane and is comprised largely of connective tissue.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002189", ontology="TAO", source="ZFIN:ZDB-PUB-061010-3"} property_value: UBPROP:0000002 "relationship type change: subclass tissue (CARO:0000043) CHANGED TO: develops_from tissue (UBERON:0000479)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002189", ontology="TAO"} property_value: UBPROP:0000002 "relationship type change: subclass tissue (CARO:0000043) CHANGED TO: has_developmental_contribution_from tissue (UBERON:0000479)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002189", ontology="TAO"} [Term] id: UBERON:0001778 name: ciliary epithelium namespace: uberon def: "A double layer covering the ciliary body that produces aqueous humor." [Wikipedia:Ciliary_body#Ciliary_epithelium] subset: human_reference_atlas synonym: "ciliary body epithelium" EXACT [FMA:58464] synonym: "epithelium of ciliary body" EXACT [FMA:58464] synonym: "ocular ciliary epithelium" EXACT [] xref: BTO:0001770 xref: CALOHA:TS-0695 xref: EMAPA:35239 xref: FMA:58464 xref: MA:0001238 xref: NCIT:C32314 xref: SCTID:280870004 xref: UMLS:C0459736 {source="ncithesaurus:Ciliary_Epithelium"} xref: Wikipedia:Ciliary_body#Ciliary_epithelium is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001775 ! ciliary body relationship: has_part GO:0048770 {source="MP"} ! pigment granule relationship: part_of UBERON:0001775 {source="MA"} ! ciliary body relationship: produces UBERON:0001796 {source="Wikipedia"} ! aqueous humor of eyeball property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001779 name: iris stroma namespace: uberon def: "The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae." [http://www.drugs.com/dict/stroma-of-iris.html, Wikipedia:Iris_stroma] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "iridial stroma" EXACT [] synonym: "stroma of iris" EXACT [] xref: EMAPA:35451 xref: FMA:58526 xref: MA:0002777 xref: SCTID:280882008 xref: Wikipedia:Iris_stroma xref: ZFA:0005569 is_a: UBERON:0003891 ! stroma is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0001769 ! iris relationship: contributes_to_morphology_of UBERON:0001769 ! iris relationship: part_of UBERON:0001769 ! iris property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png" xsd:anyURI [Term] id: UBERON:0001780 name: spinal nerve namespace: uberon def: "The any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified]." [MESH:A08.800.800.720, MP:0001077] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "backbone nerve" EXACT [OBOL:automatic] synonym: "nerve of backbone" EXACT [OBOL:automatic] synonym: "nerve of spinal column" EXACT [OBOL:automatic] synonym: "nerve of spine" EXACT [OBOL:automatic] synonym: "nerve of vertebral column" EXACT [OBOL:automatic] synonym: "nervi spinales" RELATED LATIN [Wikipedia:Spinal_nerve] synonym: "spinal column nerve" EXACT [OBOL:automatic] synonym: "spinal nerve tree" EXACT [] synonym: "spinal nerves" RELATED PLURAL [BAMS:spin] synonym: "spine nerve" EXACT [OBOL:automatic] synonym: "vertebral column nerve" EXACT [OBOL:automatic] xref: AAO:0011101 xref: BAMS:spin xref: BTO:0000870 xref: EHDAA2:0001898 xref: EMAPA:16989 xref: FMA:5858 xref: GAID:841 xref: MA:0000233 xref: MESH:D013127 xref: NCIT:C12792 xref: neuronames:1228 xref: SCTID:361099009 xref: UMLS:C0037941 {source="ncithesaurus:Spinal_Nerve"} xref: VHOG:0000824 xref: Wikipedia:Spinal_nerve xref: XAO:0003101 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: extends_fibers_into UBERON:0002240 ! spinal cord relationship: extends_fibers_into UBERON:0002240 ! spinal cord relationship: part_of RO:0002577 ! system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Any of the paired nerves emerging from the spinal cord, each attached to the cord by two roots: ventral and dorsal, and passing out between the vertebrae. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000824", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/spinal+nerve"} [Term] id: UBERON:0001781 name: layer of retina namespace: uberon def: "Any of the layers that make up the retina[MP]." [MP:0003727] subset: pheno_slim subset: vertebrate_core synonym: "retina layer" EXACT [] synonym: "retina neuronal layer" EXACT [MP:0006069] synonym: "retinal layer" EXACT [] synonym: "retinal neuronal layer" EXACT [MP:0006069] xref: AAO:0010353 xref: EMAPA:35742 xref: FMA:58617 xref: MA:0001319 xref: NCIT:C49328 xref: SCTID:280657006 xref: UMLS:C0459649 {source="ncithesaurus:Retina_Layer"} xref: XAO:0000266 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0022303 ! nervous system cell part layer relationship: contributes_to_morphology_of UBERON:0000966 ! retina relationship: part_of UBERON:0000966 ! retina property_value: UBPROP:0000012 "MA does not treat internal/external limiting memranes as layers - these are classified as laminae. Here we follow other ontologies in grouping with other layers. MA also treats retinal pigment epithelium and neural retina epithelium as distinct from the layers. We follow ontologies such as FMA and ZFA in first dividing into pigmented and neural layers - these are also classified as layers, giving us over the usual 10 layers" xsd:string {external_ontology="MA"} [Term] id: UBERON:0001785 name: cranial nerve namespace: uberon def: "Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord." [Wikipedia:Cranial_nerve] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cranial nerves" RELATED [] synonym: "cranial neural tree organ" EXACT [] synonym: "nervus cranialis" RELATED LATIN [Wikipedia:Cranial_nerve] xref: AAO:0000108 xref: BAMS:cran xref: BIRNLEX:1623 xref: BTO:0001104 xref: EHDAA2:0000323 xref: EMAPA:17264 xref: FMA:5865 xref: GAID:802 xref: HBA:9299 xref: MA:0000215 xref: MBA:967 xref: MESH:D003391 xref: NCIT:C12700 xref: neuronames:1227 xref: SCTID:244447006 xref: TAO:0000641 xref: UMLS:C0010268 {source="BIRNLEX:1623", source="ncithesaurus:Cranial_Nerve"} xref: UMLS:C1269897 {source="BIRNLEX:1623"} xref: VHOG:0000279 xref: Wikipedia:Cranial_nerve xref: XAO:0000429 xref: XAO:0003089 xref: ZFA:0000641 is_a: UBERON:0011779 ! nerve of head region is_a: UBERON:0034713 ! cranial neuron projection bundle intersection_of: UBERON:0001021 ! nerve intersection_of: anterior_to UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0000955 ! brain relationship: anterior_to UBERON:0001780 ! spinal nerve relationship: has_developmental_contribution_from UBERON:0003099 ! cranial neural crest property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/18/Brain_human_normal_inferior_view_with_labels_en-2.svg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/84/Brain_human_normal_inferior_view_with_labels_en.svg" xsd:anyURI property_value: editor_note "classified as neural tree organ, not nerve in FMA. CN II poses a challenge here as it is not strictly a nerve, yet is expected to be classified under CN." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Twelve pairs of cranial nerves exit/enter the cranium through openings in the skull. The nerves contain efferent axons with motor and glandular functions, as well as afferent axons from cranial ganglia with sensory functions. The nerves are numbered in a rostral to caudal sequence, with the exception of the lateral line nerves.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000641", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (5) cranial nerves (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000279", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "See https://github.com/obophenotype/mouse-anatomy-ontology/issues/6" xsd:string [Term] id: UBERON:0001796 name: aqueous humor of eyeball namespace: uberon def: "A thick watery refractive medium that fills the space between the lens and the cornea[WP]." [Wikipedia:Aqueous_humor] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "aqueous humor" EXACT [] synonym: "aqueous humour" EXACT [EHDAA2:0000139] synonym: "humor aquosus" EXACT LATIN [FMA:58819, FMA:TA] xref: EHDAA2:0000139 xref: EHDAA:10196 xref: EMAPA:18232 xref: ENVO:02000024 xref: FMA:58819 xref: GAID:890 xref: MA:0001236 xref: MESH:D001082 xref: NCIT:C13190 xref: SCTID:280587006 xref: UMLS:C0003662 {source="ncithesaurus:Aqueous_Humor"} xref: VHOG:0000548 xref: Wikipedia:Aqueous_humor xref: ZFA:0005564 is_a: UBERON:0006312 ! ocular refractive media is_a: UBERON:0006314 ! bodily fluid relationship: contributes_to_morphology_of UBERON:0001766 ! anterior chamber of eyeball relationship: part_of UBERON:0001766 {notes="FMA def states A and P", notes="located_in in EHDAA2", source="VHOG"} ! anterior chamber of eyeball property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI property_value: UBPROP:0000001 "The fluid produced by the ciliary process in the eye and occupying the anterior and posterior chambers. It provides nourishment for the lens and cornea and maintains the ocular pressure, and hence the optical integrity of the eyeball. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000548", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/aqueous+humour"} property_value: UBPROP:0000003 "(...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000548", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007), ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.424 and p.426 and p.429 and Figure 12-24", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "FMA says A+P chambers, and MA states A chamber. ZFA states A chamber and tha it is produced primarily by dorsal ciliary epithelial cells.To be investigated across taxa." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001800 name: sensory ganglion namespace: uberon def: "The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells." [MP:0000960] subset: pheno_slim synonym: "ganglion sensorium" EXACT LATIN [] xref: AEO:0001000 xref: BTO:0005630 xref: EMAPA:36596 xref: FMA:5885 xref: MA:0002566 xref: MESH:D017950 xref: NCIT:C13060 xref: UMLS:C0206429 {source="ncithesaurus:Sensory_Ganglion"} is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: extends_fibers_into UBERON:0001027 ! sensory nerve relationship: extends_fibers_into UBERON:0001027 ! sensory nerve relationship: part_of RO:0002577 ! system [Term] id: UBERON:0001801 name: anterior segment of eyeball namespace: uberon def: "Any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive)." [ISBN:0-683-40008-8, MESH:A09.371.060, MP:0005193] subset: pheno_slim subset: vertebrate_core synonym: "anterior eye segment" EXACT [] synonym: "anterior segment eye" EXACT [ZFA:0005566] synonym: "anterior segment of eye" EXACT [] synonym: "anterior segment of the eye" EXACT [] synonym: "eye anterior segment" EXACT [] synonym: "segmentum anterius (bulbus oculi)" EXACT [] synonym: "segmentum anterius bulbi oculi" RELATED LATIN [Wikipedia:Anterior_segment_of_eyeball] xref: EMAPA:36594 xref: FMA:58865 xref: MA:0002484 xref: MESH:D000869 xref: NCIT:C12668 xref: SCTID:280658001 xref: UMLS:C0003153 {source="ncithesaurus:Anterior_Eye_Segment"} xref: Wikipedia:Anterior_segment_of_eyeball xref: ZFA:0005566 is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004121 ! ectoderm-derived structure disjoint_from: UBERON:0001802 {source="lexical"} ! posterior segment of eyeball relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye relationship: in_anterior_side_of UBERON:0010230 {source="cjm"} ! eyeball of camera-type eye relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/ba/Cataract_in_human_eye.png" xsd:anyURI property_value: RO:0002171 UBERON:0001802 {exceptions="ZFA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"} [Term] id: UBERON:0001802 name: posterior segment of eyeball namespace: uberon def: "Any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive)." [ISBN:0-683-40008-8, MP:0005195] subset: pheno_slim subset: vertebrate_core synonym: "eye posterior segment" EXACT [] synonym: "posterior eye segment" EXACT [] synonym: "posterior segment eye" EXACT [ZFA:0005567] synonym: "posterior segment of eye" EXACT [] synonym: "posterior segment of the eye" EXACT [] synonym: "segmentum posterius (bulbus oculi)" EXACT [] synonym: "segmentum posterius bulbi oculi" RELATED LATIN [Wikipedia:Posterior_segment_of_eyeball] xref: EMAPA:36595 xref: FMA:58868 xref: MA:0002485 xref: NCIT:C12906 xref: SCTID:280659009 xref: UMLS:C0278450 {source="ncithesaurus:Posterior_Eye_Segment"} xref: Wikipedia:Posterior_segment_of_eyeball xref: ZFA:0005567 is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004121 ! ectoderm-derived structure relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye relationship: in_posterior_side_of UBERON:0010230 {source="cjm"} ! eyeball of camera-type eye relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Schematic_diagram_of_the_human_eye_en.svg" xsd:anyURI [Term] id: UBERON:0001803 name: epithelium of lens namespace: uberon def: "A layer of epithelial cells that is part of the eye." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "epithelial tissue of eye lens" EXACT [OBOL:automatic] synonym: "epithelial tissue of lens" EXACT [OBOL:automatic] synonym: "epithelium lentis" EXACT LATIN [FMA:58871, FMA:TA] synonym: "epithelium of eye lens" EXACT [OBOL:automatic] synonym: "eye lens epithelial tissue" EXACT [OBOL:automatic] synonym: "eye lens epithelium" EXACT [OBOL:automatic] synonym: "lens epithelial tissue" EXACT [OBOL:automatic] synonym: "lens epithelium" EXACT [] xref: BTO:0001873 xref: CALOHA:TS-0543 xref: EMAPA:32871 xref: FMA:58871 xref: MA:0001301 xref: SCTID:362523006 xref: TAO:0001326 xref: Wikipedia:Lens_(anatomy)#Lens_Epithelium xref: XAO:0004094 xref: ZFA:0001326 is_a: UBERON:0000484 ! simple cuboidal epithelium is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000965 ! lens of camera-type eye relationship: contributes_to_morphology_of UBERON:0000965 ! lens of camera-type eye relationship: part_of UBERON:0000965 ! lens of camera-type eye property_value: IAO:0000232 "this class is the superclass of the anterior epithelium and equatorial epithlium, although the term 'lens epithelium' may refer specifically to the former" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001804 name: capsule of lens namespace: uberon def: "The elastic, clear, membrane-like structure, that is outer most layer of the lens." [MGI:smb, MP:0003236, PMID:15483628] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "capsula lentis" EXACT LATIN [] synonym: "lens capsule" EXACT [] xref: EHDAA2:0000977 xref: EMAPA:18237 xref: FMA:58881 xref: MA:0001300 xref: NCIT:C32975 xref: SCTID:244500004 xref: UMLS:C0229232 {source="ncithesaurus:Lens_Capsule"} xref: VHOG:0000550 xref: Wikipedia:Lens_(anatomy)#Lens_capsule xref: ZFA:0005574 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005764 ! acellular membrane intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: bounding_layer_of UBERON:0000965 ! lens of camera-type eye relationship: bounding_layer_of UBERON:0000965 ! lens of camera-type eye relationship: develops_from UBERON:0005614 {source="EHDAA2"} ! lens anterior epithelium relationship: has_part CHEBI:35722 ! sulfated glycosaminoglycan relationship: has_part GO:0005587 ! collagen type IV trimer relationship: has_quality PATO:0000964 ! transparent relationship: part_of UBERON:0000965 ! lens of camera-type eye property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray883.png" xsd:anyURI property_value: UBPROP:0000001 "The transparent membrane which surrounds the lens of the eye. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000550", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "(...) we reach the inescapable conclusion that the last common ancestor of jawless and jawed vertebrates already possessed an eye that was comparable to that of extant lampreys and gnathostomes. Accordingly, a vertebrate camera-like eye must have been present by the time that lampreys and gnathostomes diverged, around 500 Mya (reference 1); Although the eye varies greatly in adaptative details among vertebrates, its basic structure is the same in all. The human eye is representative of the design typical for a tetrapod. (...) A watery aqueous humor fills the spaces in the eye in front of the lens (...) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000550", ontology="VHOG", source="DOI:10.1038/nrn2283 Lamb TD, Collin SP and Pugh EN Jr, Evolution of the vertebrate eye: opsins, photoreceptors, retina and eye cup. Nature Reviews Neuroscience (2007), ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.424 and p.426 and p.429 and Figure 12-24", source="http://bgee.unil.ch/"} property_value: UBPROP:0000010 "synthesized by the lens epithelium and its main components are Type IV collagen and sulfated glycosaminoglycans (GAGs). [Wikipedia:Capsule_of_lens" xsd:string property_value: UBPROP:0000012 "FMA classifies this is a capsule and hence an organ part. In contrast we classify this as acellular" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001805 name: autonomic ganglion namespace: uberon def: "Ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion." [Wikipedia:Autonomic_ganglion] subset: uberon_slim synonym: "autonomic nervous system ganglion" EXACT [OBOL:automatic] synonym: "ganglion autonomicum" RELATED LATIN [Wikipedia:Autonomic_ganglion] synonym: "ganglion of autonomic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of visceral nervous system" EXACT [OBOL:automatic] synonym: "visceral nervous system ganglion" EXACT [OBOL:automatic] xref: AEO:0001001 xref: CALOHA:TS-2340 xref: EMAPA:17157 xref: EMAPA:18221 xref: FMA:5889 xref: MA:0000220 xref: MESH:D005725 xref: NCIT:C12720 xref: UMLS:C0017068 {source="ncithesaurus:Autonomic_Ganglion"} xref: Wikipedia:Autonomic_ganglion is_a: UBERON:0003338 ! ganglion of peripheral nervous system intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0002410 ! autonomic nervous system relationship: extends_fibers_into UBERON:0034728 ! autonomic nerve relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002410 ! autonomic nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI [Term] id: UBERON:0001806 name: sympathetic ganglion namespace: uberon def: "A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia." [http://orcid.org/0000-0002-6601-2165, MP:0001008] subset: pheno_slim subset: uberon_slim synonym: "ganglion of sympathetic nervous system" EXACT [OBOL:automatic] synonym: "ganglion of sympathetic part of autonomic division of nervous system" EXACT [OBOL:automatic] synonym: "ganglion sympatheticum" EXACT [] synonym: "ganglion sympathicum" RELATED LATIN [BTO:0001333, Wikipedia:Sympathetic_ganglion] synonym: "sympathetic nervous system ganglion" EXACT [OBOL:automatic] synonym: "sympathetic part of autonomic division of nervous system ganglion" EXACT [OBOL:automatic] xref: AAO:0010773 xref: BTO:0001333 xref: CALOHA:TS-0994 xref: EHDAA2:0001969 xref: EMAPA:17157 xref: FMA:5890 xref: MA:0000226 xref: MESH:D005728 xref: NCIT:C12467 xref: SCTID:362485003 xref: UMLS:C0017071 {source="ncithesaurus:Sympathetic_Ganglion"} xref: Wikipedia:Sympathetic_ganglion is_a: UBERON:0001805 ! autonomic ganglion is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0000013 ! sympathetic nervous system relationship: contributes_to_morphology_of UBERON:0000013 ! sympathetic nervous system relationship: develops_from UBERON:0003083 {source="DOI:10.1101/gr.157586.113", source="ISBN:0073040584"} ! trunk neural crest relationship: extends_fibers_into UBERON:0034729 ! sympathetic nerve relationship: part_of UBERON:0000013 ! sympathetic nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI [Term] id: UBERON:0001808 name: parasympathetic ganglion namespace: uberon def: "Ganglion containing neurons that receive innervation from parasympathetic neurons in the central nervous system and subserves parasympathetic functions through innervation of smooth muscle, cardiac muscle and glands." [NLXANAT:100303] subset: pheno_slim subset: uberon_slim synonym: "ganglion parasympathicum" RELATED LATIN [BTO:0001256, Wikipedia:Parasympathetic_ganglion] xref: BTO:0001256 xref: EHDAA2:0001400 xref: EMAPA:32813 xref: FMA:5894 xref: MA:0002469 xref: MESH:D005726 xref: NCIT:C52557 xref: NLXANAT:100303 xref: SCTID:279284004 xref: UMLS:C0017069 {source="ncithesaurus:Parasympathetic_Ganglion"} xref: Wikipedia:Parasympathetic_ganglion is_a: UBERON:0001805 ! autonomic ganglion is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001805 ! autonomic ganglion intersection_of: part_of UBERON:0000011 ! parasympathetic nervous system relationship: contributes_to_morphology_of UBERON:0000011 ! parasympathetic nervous system relationship: extends_fibers_into UBERON:0004293 ! parasympathetic nerve relationship: part_of UBERON:0000011 ! parasympathetic nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI [Term] id: UBERON:0001810 name: nerve plexus namespace: uberon def: "Anatomical junction where subdivisions of two or more neural trees interconnect with one another to form a network through which nerve fibers of the constituent nerve trees become regrouped; together with other nerve plexuses, nerves and ganglia, it constitutes the peripheral nervous system. Examples: cervical nerve plexus, brachial nerve plexus, sacral nerve plexus[FMA]." [FMA:5901, https://github.com/obophenotype/cell-ontology/issues/1306, Wikipedia:Nervous_system_plexus] subset: human_reference_atlas subset: uberon_slim synonym: "plexus" BROAD [] xref: AEO:0000138 xref: BTO:0000205 xref: EHDAA2:0003138 xref: EHDAA:3780 xref: EMAPA:37683 {source="MA:th"} xref: FMA:5901 xref: MA:0002407 xref: NCIT:C12929 xref: SCTID:122455009 xref: UMLS:C0501403 {source="ncithesaurus:Nerve_Plexus"} xref: Wikipedia:Nervous_system_plexus is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0007651 ! anatomical junction relationship: has_part CL:0000526 {source="AEO"} ! afferent neuron relationship: has_part CL:0000527 {source="AEO"} ! efferent neuron relationship: part_of UBERON:0001016 ! nervous system property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "Made to be a subtype of junction rather than tissue to be consistent with FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001813 name: spinal nerve plexus namespace: uberon def: "An intermingling of fiber fascicles from adjacent spinal nerves to form a network." [http://www.medilexicon.com/medicaldictionary.php?t=70024] synonym: "plexus nervorum spinalium" EXACT LATIN [FMA:5903, FMA:TA] synonym: "plexus of spinal nerves" EXACT [FMA:5903] synonym: "somatic nerve plexus" EXACT [FMA:5903] synonym: "spinal nerve plexus" EXACT [FMA:5903] xref: EHDAA2:0001899 xref: EMAPA:16987 xref: FMA:5903 xref: MA:0000235 xref: NCIT:C49601 xref: SCTID:42280003 xref: UMLS:C0228603 {source="ncithesaurus:Spinal_Nerve_Plexus"} xref: VHOG:0000925 is_a: UBERON:0001810 ! nerve plexus intersection_of: UBERON:0001810 ! nerve plexus intersection_of: extends_fibers_into UBERON:0001780 ! spinal nerve relationship: extends_fibers_into UBERON:0001780 ! spinal nerve relationship: part_of RO:0002577 ! system property_value: UBPROP:0000003 "To reach the muscles, dermatomes, and other structures of the limbs, some of the neurons in the spinal nerves come together in the plexus at the base of the limb. Such plexuses occur in all gnathostomes, and they reach their highest complexity among mammals and birds in which the cervical plexus supplies many ventral neck muscles, the brachial plexus supplies the pectoral appendage, a lumbosacral plexus supplies the pelvic appendage, and a coccygeal plexus supplies some of the pelvic muscles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000926", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.436", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001814 name: brachial nerve plexus namespace: uberon def: "An arrangement of nerve fibers, running from the spine where it proceeds through the neck then the axilla and into the arm where it innervates skin and muscle. [WP,modified]." [UBERON:cjm, Wikipedia:Brachial_plexus] subset: human_reference_atlas subset: uberon_slim synonym: "brachial plexus" EXACT [MA:0001180] synonym: "plexus brachialis" RELATED LATIN [Wikipedia:Brachial_plexus] xref: EHDAA2:0000180 xref: EHDAA:3782 xref: EMAPA:16988 xref: FMA:5906 xref: GAID:842 xref: MA:0001180 xref: MESH:D001917 xref: NCIT:C12682 xref: SCTID:181002002 xref: UMLS:C0006090 {source="ncithesaurus:Brachial_Plexus"} xref: VHOG:0000372 xref: Wikipedia:Brachial_plexus is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001813 ! spinal nerve plexus relationship: innervates UBERON:0002102 ! forelimb property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3a/Gray808.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c9/Brachial_plexus_color.svg" xsd:anyURI property_value: editor_note "check superclass - nerve vs collection of fibers vs junction; note that FMA also has 'brachial autonomic nerve plexus'" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A nerve plexus originating from the anterior branches of the last four cervical and the first thoracic spinal nerves, giving off many of the principal nerves of the shoulder, chest, and arms. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000372", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/brachial+plexus"} property_value: UBPROP:0000003 "To reach the muscles, dermatomes, and other structures of the limbs, some of the neurons in the spinal nerves come together in the plexus at the base of the limb. Such plexuses occur in all gnathostomes, and they reach their highest complexity among mammals and birds in which the cervical plexus supplies many ventral neck muscles, the brachial plexus supplies the pectoral appendage, a lumbosacral plexus supplies the pelvic appendage, and a coccygeal plexus supplies some of the pelvic muscles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000372", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.436", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001815 name: lumbosacral nerve plexus namespace: uberon def: "An arrangement of nerve fibers, running from the spine that travels to the pelvic appendage where it innervates skin and muscle." [UBERON:cjm] subset: uberon_slim synonym: "lumbosacral plexus" EXACT [] synonym: "plexus lumbosacralis" EXACT LATIN [FMA:5907, FMA:TA] synonym: "plexus lumbosacralis" RELATED LATIN [Wikipedia:Lumbosacral_plexus] xref: BAMS:lsp xref: EHDAA2:0001040 xref: EHDAA:4673 xref: EMAPA:17587 xref: FMA:5907 xref: GAID:849 xref: MA:0001181 xref: MESH:D008160 xref: NCIT:C52805 xref: SCTID:181049003 xref: UMLS:C0024093 {source="ncithesaurus:Lumbosacral_Plexus"} xref: VHOG:0000926 xref: Wikipedia:Lumbosacral_plexus is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001813 ! spinal nerve plexus relationship: innervates UBERON:0002103 ! hindlimb property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8d/Gray822.png" xsd:anyURI [Term] id: UBERON:0001816 name: autonomic nerve plexus namespace: uberon def: "A nerve plexus that is part of an autonomic nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "autonomic plexus" EXACT [] synonym: "plexus autonomicus" EXACT LATIN [FMA:5910, FMA:TA] synonym: "plexus nervosus visceralis" EXACT LATIN [FMA:5910, FMA:TA] synonym: "plexus visceralis" EXACT LATIN [FMA:5910, FMA:TA] synonym: "visceral nerve plexus" EXACT [] synonym: "visceral plexus" EXACT [] xref: EMAPA:18224 xref: FMA:5910 xref: MA:0000221 xref: SCTID:362482000 is_a: UBERON:0001810 ! nerve plexus intersection_of: UBERON:0001810 ! nerve plexus intersection_of: part_of UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0002410 ! autonomic nervous system [Term] id: UBERON:0001823 name: nasal cartilage namespace: uberon def: "One of the cartilage structures in the nose that provide form and support[WP]." [Wikipedia:Nasal_cartilage] subset: pheno_slim subset: uberon_slim synonym: "cartilage of nose" EXACT [] xref: CALOHA:TS-0655 xref: EMAPA:37681 {source="MA:th"} xref: FMA:59502 xref: MA:0001883 xref: MESH:D055171 xref: NCIT:C49593 xref: SCTID:278941001 xref: UMLS:C0225415 {source="ncithesaurus:Nasal_Cartilage"} xref: Wikipedia:Nasal_cartilage is_a: UBERON:0002418 {source="MA"} ! cartilage tissue is_a: UBERON:0003566 ! head connective tissue is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0000004 ! nose relationship: location_of UBERON:0000402 ! nasal vestibule relationship: part_of UBERON:0000004 ! nose property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e1/Gray852.png" xsd:anyURI [Term] id: UBERON:0001824 name: mucosa of larynx namespace: uberon def: "The mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx." [MP:0002261] synonym: "laryngeal mucosa" EXACT [] synonym: "laryngeal mucous membrane" RELATED [EMAPA:18334] synonym: "larynx mucosa" EXACT [] synonym: "larynx mucosa of organ" EXACT [OBOL:automatic] synonym: "larynx mucous membrane" EXACT [OBOL:automatic] synonym: "larynx organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of larynx" EXACT [OBOL:automatic] synonym: "mucous membrane of larynx" EXACT [] synonym: "organ mucosa of larynx" EXACT [OBOL:automatic] synonym: "tunica mucosa laryngis" EXACT LATIN [FMA:59662, FMA:TA] xref: EMAPA:18334 xref: FMA:59662 xref: GAID:301 xref: MA:0001766 xref: MESH:D007820 xref: NCIT:C49246 xref: SCTID:361940006 xref: UMLS:C0023053 {source="ncithesaurus:Laryngeal_Mucosa"} is_a: UBERON:0000379 ! tracheal mucosa is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001737 ! larynx [Term] id: UBERON:0001826 name: nasal cavity mucosa namespace: uberon def: "The mucous membrane that lines the nasal cavity[MP]." [MP:0002238] subset: pheno_slim synonym: "mucosa of nose" EXACT [FMA:59684] synonym: "mucous membrane of nose" EXACT [FMA:59684] synonym: "nasal mucosa" RELATED [] synonym: "tunica mucosa nasalis" EXACT [] synonym: "tunica mucosa nasi" EXACT LATIN [FMA:59684, FMA:TA] xref: BTO:0000912 xref: CALOHA:TS-0657 xref: EMAPA:36026 xref: FMA:59684 xref: GAID:302 xref: SCTID:310211009 xref: Wikipedia:Mucous_membrane_of_nose is_a: UBERON:0000379 ! tracheal mucosa is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0015788 ! olfactory apparatus chamber relationship: bounding_layer_of UBERON:0015788 ! olfactory apparatus chamber relationship: part_of UBERON:0015788 ! olfactory apparatus chamber property_value: editor_note "TODO - check lining vs part of. split olfactory and nasal mucosa?" xsd:string [Term] id: UBERON:0001828 name: gingiva namespace: uberon def: "The fibrous investing tissue, covered by keratinized epithelium, that immediately surrounds a tooth and is contiguous with its periodontal ligament and with the mucosal tissues of the mouth[Glossary of Periodontal Terms 2001]." [ISBN:0013002015, Wikipedia:Gingiva] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "gingival mucosa" RELATED [] synonym: "gum" EXACT [FMA:59762] synonym: "gum tissue" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "gums" EXACT [] xref: BTO:0000519 xref: CALOHA:TS-2074 xref: EFO:0001925 xref: EMAPA:35945 xref: EV:0100064 xref: FMA:59762 xref: GAID:1257 xref: galen:Gingiva xref: MA:0000342 xref: MESH:D005881 xref: NCIT:C32677 xref: SCTID:181224006 xref: UMLS:C0017562 {source="ncithesaurus:Gingiva"} xref: VHOG:0001269 xref: Wikipedia:Gingiva is_a: UBERON:0003729 ! mouth mucosa relationship: adjacent_to UBERON:0004103 ! alveolar ridge relationship: adjacent_to UBERON:0008266 ! periodontal ligament relationship: continuous_with UBERON:0003729 {source="ISBN:0013002015"} ! mouth mucosa relationship: part_of UBERON:0003729 {source="Carranza"} ! mouth mucosa relationship: part_of UBERON:0011595 ! jaw region property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/2/2e/Tooth_Section.svg" xsd:anyURI property_value: editor_note "FMA has a 3-level breakdown of jaws into: region, jaw (skeleton+gums), skeleton." xsd:string property_value: UBPROP:0000007 "gingival" xsd:string [Term] id: UBERON:0001833 name: lip namespace: uberon def: "One of the two fleshy folds which surround the opening of the mouth." [http://www.medterms.com/script/main/art.asp?articlekey=9458, Wikipedia:Lip] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "labia oris" RELATED LATIN [Wikipedia:Lip] synonym: "lips" RELATED [] xref: BTO:0001647 xref: CALOHA:TS-0558 xref: EMAPA:32839 xref: FMA:59816 xref: GAID:76 xref: galen:Lip xref: MA:0000343 xref: MESH:D008046 xref: NCIT:C12220 xref: SCTID:181221003 xref: TAO:0007006 xref: UMLS:C0023759 {source="ncithesaurus:Lip"} xref: VHOG:0000677 xref: Wikipedia:Lip xref: ZFA:0007006 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003102 {source="ZFA"} ! surface structure relationship: contributes_to_morphology_of UBERON:0000165 ! mouth relationship: part_of UBERON:0000165 {source="BTO", source="FMA-implicit", source="VHOG", source="ZFA"} ! mouth relationship: surrounds UBERON:0000166 {source="cjm"} ! oral opening property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/90/Lips.JPG" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg" xsd:anyURI property_value: RO:0002161 NCBITaxon:8782 property_value: UBPROP:0000001 "Surface structure that is one of the two fleshy folds surrounding the opening of the mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0007006", ontology="TAO", source="ZFIN:curator", source="http//:www.medterms.com/script/main/art.asp?articlekey=9458"} property_value: UBPROP:0000007 "labial" xsd:string [Term] id: UBERON:0001834 name: upper lip namespace: uberon alt_id: UBERON:0003391 def: "Lip that covers the upper portion of the mouth.[TAO]." [TAO:0001970, Wikipedia:Upper_lip] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "labium superius oris" RELATED LATIN [Wikipedia:Upper_lip] synonym: "upper jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:17925 xref: FMA:59817 xref: MA:0000919 xref: SCTID:245776003 xref: TAO:0001970 xref: VHOG:0001750 xref: Wikipedia:Upper_lip xref: ZFA:0005226 is_a: UBERON:0001833 ! lip intersection_of: UBERON:0001833 ! lip intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: develops_from UBERON:0011592 ! future upper lip relationship: immediate_transformation_of UBERON:0011592 ! future upper lip relationship: part_of UBERON:0001709 ! upper jaw region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d4/Illu01_head_neck.jpg" xsd:anyURI property_value: UBPROP:0000001 "Lip that covers the lower portion of the mouth. [ZFIN:Curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001750", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Lip that covers the upper portion of the mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001970", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0001835 name: lower lip namespace: uberon alt_id: UBERON:0003392 def: "Lip that covers the lower portion of the mouth.[TAO]." [TAO:0002060, Wikipedia:Lower_lip] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "labium inferius oris" RELATED LATIN [Wikipedia:Lower_lip] synonym: "lower jaw lip" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001020 xref: EMAPA:17909 xref: FMA:59818 xref: MA:0000921 xref: NCIT:C94572 xref: SCTID:245777007 xref: TAO:0002060 xref: UMLS:C0458583 {source="ncithesaurus:Lower_Lip"} xref: Wikipedia:Lower_lip xref: ZFA:0005225 is_a: UBERON:0001833 ! lip intersection_of: UBERON:0001833 ! lip intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: develops_from UBERON:0011596 ! future lower lip relationship: part_of UBERON:0001710 ! lower jaw region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/99/Mouth.jpg" xsd:anyURI property_value: UBPROP:0000001 "Lip that covers the lower portion of the mouth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002060", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0001846 name: internal ear namespace: uberon def: "Complex labyrinthine structure that comprises sensory endorgans specialized for vestibular, auditory, and acoustico-vestibular sensation." [PMID:16217737, Wikipedia:Internal_ear, ZFIN:curator] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "auris interna" RELATED [BTO:0000630] synonym: "inner ear" EXACT [] synonym: "labyrinth" RELATED [] synonym: "otocyst" RELATED [] xref: AAO:0000238 xref: BIRNLEX:1196 xref: BTO:0000630 xref: CALOHA:TS-0478 xref: EFO:0001363 xref: EHDAA2:0000831 xref: EHDAA:504 xref: EMAPA:16194 xref: EV:0100361 xref: FMA:60909 xref: GAID:871 xref: galen:InnerEar xref: MA:0000237 xref: MAT:0000145 xref: MESH:D007758 xref: MIAA:0000145 xref: NCIT:C12499 xref: SCTID:181189006 xref: SCTID:304982002 xref: TAO:0000217 xref: UMLS:C0022889 {source="ncithesaurus:Internal_Ear", source="BIRNLEX:1196"} xref: UMLS:C1268973 {source="BIRNLEX:1196"} xref: VHOG:0000284 xref: Wikipedia:Internal_ear xref: XAO:0000192 xref: ZFA:0000217 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034921 ! multi organ part structure relationship: develops_from UBERON:0003051 {evidence="definitional"} ! ear vesicle relationship: part_of UBERON:0001690 ! ear property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray923.png" xsd:anyURI property_value: UBPROP:0000001 "The auditory (hearing) and vestibular (balance) organ of the fish, equivalent to the inner ear of amniotes. (See Anatomical Atlas entry for ear by T. Whitfield.)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000217", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The labyrinth, or inner ear, evolved very early in vertebrate history and, with many variations in configuration but none of basic design and function, has been retained by all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000284", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.366", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001848 name: auricular cartilage namespace: uberon def: "Cartilage of the pinna and much of the external ear canal." [http://medical-dictionary.thefreedictionary.com/auricular+cartilage] subset: pheno_slim synonym: "cartilage of pinna" EXACT [FMA:61013] synonym: "pinna cartilage" EXACT [] xref: EMAPA:35158 xref: FMA:61013 xref: MA:0001227 xref: SCTID:279627003 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034944 ! zone of organ intersection_of: UBERON:0034944 ! zone of organ intersection_of: part_of UBERON:0001757 ! pinna intersection_of: part_of UBERON:0001867 ! cartilage of external ear relationship: part_of UBERON:0001757 ! pinna relationship: part_of UBERON:0001867 ! cartilage of external ear [Term] id: UBERON:0001851 name: cortex namespace: uberon def: "Outermost layer of an organ[WP]." [Wikipedia:Cortex_(anatomy)] subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "cortex" EXACT [FMA:61109] synonym: "cortex of organ" EXACT [] xref: EFO:0000383 xref: EHDAA:9344 xref: FMA:61109 xref: galen:Cortex xref: Wikipedia:Cortex_(anatomy) is_a: UBERON:0000064 ! organ part relationship: bounding_layer_of UBERON:0000062 ! organ property_value: UBPROP:0000007 "cortical" xsd:string property_value: UBPROP:0000012 "this class is used more generically than in FMA, and includes e.g. cortex of hair" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001867 name: cartilage of external ear namespace: uberon def: "A cartilage that is part of a external ear [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "external ear cartilage" EXACT [] xref: EMAPA:37706 {source="MA:th"} xref: FMA:61339 xref: GAID:103 xref: MA:0001886 xref: MESH:D004425 xref: NCIT:C49225 xref: UMLS:C0013445 {source="ncithesaurus:External_Ear_Cartilage"} is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0001691 ! external ear relationship: composed_primarily_of UBERON:0001996 ! elastic cartilage tissue relationship: part_of UBERON:0001691 ! external ear [Term] id: UBERON:0001869 name: cerebral hemisphere namespace: uberon def: "One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA]." [FMA:61817, Wikipedia:Cerebral_hemisphere] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "cerebrum" RELATED [https://github.com/obophenotype/uberon/issues/1208, MA:0000133, VHOG:0001639] synonym: "hemisphere" RELATED [VHOG:0001639] synonym: "hemispheric regions" RELATED [BAMS:HEM] synonym: "hemispherium cerebri" RELATED LATIN [Wikipedia:Cerebral_hemisphere] synonym: "medial amygdalar nucleus" RELATED [NeuroNames:241] synonym: "nucleus amygdaloideus medialis" RELATED LATIN [NeuroNames:241] synonym: "nucleus medialis amygdalae" RELATED LATIN [NeuroNames:241] xref: AAO:0010480 xref: BAMS:HEM xref: BIRNLEX:1042 xref: BTO:0000231 xref: CALOHA:TS-2007 xref: DMBA:15739 xref: EFO:0002521 xref: EMAPA:16653 xref: FMA:61817 xref: galen:CerebralHemisphere xref: MA:0000133 xref: MBA:403 xref: NCIT:C12351 xref: neuronames:241 {source="BIRNLEX:1042"} xref: SCTID:278251007 xref: UMLS:C0228174 {source="ncithesaurus:Cerebral_Hemisphere"} xref: UMLS:C0242202 {source="BIRNLEX:1042"} xref: VHOG:0001639 xref: Wikipedia:Cerebral_hemisphere is_a: UBERON:0000064 ! organ part is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0015212 ! lateral structure relationship: in_lateral_side_of UBERON:0000955 ! brain relationship: in_lateral_side_of UBERON:0001893 {source="FMA-abduced-lr"} ! telencephalon relationship: part_of UBERON:0001893 ! telencephalon property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/92/Hemispheres.png" xsd:anyURI property_value: UBPROP:0000001 "Part of the telencephalon consisting of either of the two smooth, elongated halves of the cerebrum.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010480", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "The presence of paired evaginated hemispheres and olfactory bulbs in both agnathan and gnathostome radiations suggests that such hemispheres were also present in the common ancestor.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001639", ontology="VHOG", source="DOI:10.1146/annurev.ne.04.030181.001505 Northcutt RG, Evolution of the telencephalon in nonmammals. Ann. Rev. Neurosci. (1981)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001884 name: phrenic nerve namespace: uberon def: "A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium." [VHOG:0000728] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "diaphragmatic nerve" RELATED [BTO:0001063] synonym: "nervus phrenicus" RELATED LATIN [BTO:0001063, Wikipedia:Phrenic_nerve] synonym: "phrenic" RELATED [BTO:0001063] xref: BAMS:phn xref: BTO:0001063 xref: EHDAA:4677 xref: EMAPA:17813 xref: FMA:6191 xref: GAID:848 xref: MA:0001170 xref: MESH:D010791 xref: NCIT:C52813 xref: SCTID:280344009 xref: UMLS:C0031774 {source="ncithesaurus:Phrenic_Nerve"} xref: VHOG:0000728 xref: Wikipedia:Phrenic_nerve is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0003443 ! thoracic cavity nerve intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0001103 ! diaphragm relationship: branching_part_of UBERON:0000962 ! nerve of cervical vertebra relationship: innervates UBERON:0001103 ! diaphragm relationship: part_of UBERON:0000962 ! nerve of cervical vertebra property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3c/Gray806.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000728", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/phrenic+nerve"} [Term] id: UBERON:0001890 name: forebrain namespace: uberon def: "The most anterior region of the brain including both the telencephalon and diencephalon." [Wikipedia:Forebrain, ZFIN:ZDB-PUB-961014-576] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "FB" BROAD ABBREVIATION [BIRNLEX:1509, NIFSTD:NeuroNames_abbrevSource] synonym: "prosencephalon" RELATED [] xref: AAO:0010147 xref: BAMS:FB xref: BAMS:Forebrain xref: BIRNLEX:1509 xref: BTO:0000478 xref: CALOHA:TS-0380 xref: DHBA:10156 xref: DMBA:15566 xref: EFO:0000909 xref: EHDAA2:0000556 xref: EHDAA:3470 xref: EMAPA:16895 xref: FMA:61992 xref: MA:0000170 xref: MAT:0000105 xref: MESH:D016548 xref: MIAA:0000105 xref: NCIT:C40185 xref: neuronames:27 {source="BIRNLEX:1509"} xref: SCTID:362291003 xref: TAO:0000109 xref: UMLS:C0085140 {source="ncithesaurus:Fore-Brain", source="BIRNLEX:1509"} xref: VHOG:0000383 xref: Wikipedia:Forebrain xref: XAO:0000011 xref: ZFA:0000109 is_a: UBERON:0002616 ! regional part of brain disjoint_from: UBERON:0002298 ! brainstem relationship: contributes_to_morphology_of UBERON:0000955 ! brain relationship: develops_from UBERON:0003080 ! anterior neural tube relationship: develops_from UBERON:0006240 ! future forebrain relationship: immediate_transformation_of UBERON:0006240 {evidence="definitional"} ! future forebrain property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Most anterior of the three regions of the brain consisting of the telencephalon and diencephalon.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010147", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The most anterior region the brain including both the telencephalon and diencephalon. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000109", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from forebrain neural tube (TAO:0007041)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000109", ontology="TAO"} property_value: UBPROP:0000003 "In craniate embryos, neural expression of Distal-less-related genes is exclusively in the forebrain (...). Because the major neural expression domain of amphioxus AmphiDll is in the anterior three-fourths of the cerebral vesicle, we suggest that this region of the neural tube is homologous to parts of the craniate forebrain. This conclusion is strongly supported by three-dimensional, computer-assisted reconstruction of the neural tube of amphioxus based on serial transmission electron microscopy. At the neuroanatomical level, a number of detailed homologies are indicated between the anterior three-fourths of the amphioxus cerebral vesicle and the diencephalic region of the craniate forebrain. If one assumes that the amphioxus condition fairly represents the nervous system of the proximate ancestor of the craniates, one can suggest that they evolved from a creature that had the beginnings of a forebrain.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000383", ontology="VHOG", source="PMID:8787764 Holland ND, Panganiban G, Henyey EL, Holland LZ, Sequence and developmental expression of AmphiDll, an amphioxus Distal-less gene transcribed in the ectoderm, epidermis and nervous system: insights into evolution of craniate forebrain and neural crest. Development (1996)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "prosencephalic" xsd:string [Term] id: UBERON:0001891 name: midbrain namespace: uberon def: "The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]." [GO:0030901] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "MB" BROAD ABBREVIATION [BIRNLEX:1667, NIFSTD:NeuroNames_abbrevSource] synonym: "mesencephalon" RELATED LATIN [Wikipedia:Midbrain] xref: AAO:0010149 xref: BAMS:MES xref: BIRNLEX:1667 xref: BM:MB xref: BTO:0000138 xref: CALOHA:TS-0630 xref: DHBA:10648 xref: DMBA:16649 xref: EFO:0000919 xref: EHDAA2:0001162 xref: EHDAA:3694 xref: EMAPA:16974 xref: EV:0100242 xref: FMA:61993 xref: HBA:9001 xref: MA:0000207 xref: MAT:0000106 xref: MBA:313 xref: MESH:D008636 xref: MIAA:0000106 xref: NCIT:C12510 xref: neuronames:462 {source="BIRNLEX:1667"} xref: RETIRED_EHDAA2:0001104 xref: SCTID:279099009 xref: TAO:0000128 xref: UMLS:C0025462 {source="BIRNLEX:1667", source="ncithesaurus:Mesencephalon"} xref: VHOG:0000069 xref: Wikipedia:Midbrain xref: XAO:0000014 xref: ZFA:0000128 is_a: UBERON:0002616 ! regional part of brain is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: contributes_to_morphology_of UBERON:0000955 ! brain relationship: develops_from UBERON:0009616 ! presumptive midbrain relationship: has_developmental_contribution_from UBERON:0003849 {evidence="definitional"} ! mesencephalic neural crest relationship: immediate_transformation_of UBERON:0009616 {source="Bgee:AN"} ! presumptive midbrain property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f9/Human_brain_inferior_view_description.JPG" xsd:anyURI property_value: editor_note "developmental relationships need revised" xsd:string property_value: RO:0002171 UBERON:0001894 {exceptions="ZFA", exceptions_url="https://github.com/obophenotype/uberon/issues/378", source="ABA", status="pending"} property_value: RO:0002171 UBERON:0002028 {exceptions="ZFA", source="ABA", status="pending"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Middle part of the brain composed of the optic tectum and penducular region.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010149", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The brain region between the forebrain anteriorly and the hindbrain posteriorly, including the tectum dorsally and the midbrain tegmentum ventrally. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000128", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000069", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "mesencephalic" xsd:string property_value: UBPROP:0000012 "part of brainstem in ABA - we reject this in favor of ISBN:0471888893 which has an implicit overlaps relationships" xsd:string {external_ontology="ABA"} [Term] id: UBERON:0001892 name: rhombomere namespace: uberon def: "A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]." [Wikipedia:Rhombomere, ZFIN:curator] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "future rhombencephalon" RELATED [MIAA:0000272] synonym: "hindbrain neuromere" EXACT [] synonym: "hindbrain neuromeres" EXACT PLURAL [DHBA:HNM] synonym: "hindbrain segment" BROAD [ZFA:0001064] synonym: "rhombomere" EXACT [] synonym: "rhombomeres" RELATED PLURAL [VHOG:0000672] synonym: "segment of hindbrain" BROAD [ZFA:0001064] xref: DHBA:12664 xref: EFO:0003617 xref: EMAPA:16148 xref: FMA:295666 xref: MAT:0000272 xref: MIAA:0000272 xref: RETIRED_EHDAA2:0000669 xref: TAO:0001064 xref: VHOG:0000672 xref: Wikipedia:Rhombomere xref: XAO:0004079 xref: ZFA:0001064 is_a: UBERON:0004731 ! neuromere intersection_of: UBERON:0004731 ! neuromere intersection_of: part_of UBERON:0007277 ! presumptive hindbrain relationship: part_of UBERON:0007277 ! presumptive hindbrain property_value: UBPROP:0000001 "A segment of the developing hindbrain. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001064", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Rhombomeric segmentation is found in all living vertebrates and is of fundamental importance to the development of the vertebrate head.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000672", ontology="VHOG", source="DOI:10.1006/dbio.2002.0831 Mazet F, Shimeld SM, The Evolution of Chordate Neural Segmentation. Developmental Biology (2002)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In human embryonic development, the rhombomeres are present by day 29" xsd:string property_value: UBPROP:0000012 "DHBA divides this into A(1-3),B(4),C(5-7) and D(8)" xsd:string [Term] id: UBERON:0001893 name: telencephalon namespace: uberon def: "Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres." [AAO:0010479, XAO:0000012] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebrum" EXACT [BTO:0000239, EMAPA:16910, FMA:62000, https://github.com/obophenotype/uberon/issues/1208, Wikipedia:Talk\:Cerebrum/Archive_1] synonym: "endbrain" EXACT [neuronames:31, Swanson:2004] synonym: "supratentorial region" BROAD [Wikipedia:Tentorium_cerebelli] xref: AAO:0010479 xref: BAMS:CB xref: BAMS:CH xref: BAMS:IV xref: BAMS:Tel xref: BIRNLEX:1115 xref: BM:Tel xref: BTO:0000239 xref: CALOHA:TS-1018 xref: DHBA:10158 xref: EFO:0000912 xref: EHDAA2:0001982 xref: EMAPA:16910 xref: EV:0100165 xref: FMA:62000 xref: GAID:621 xref: HBA:4007 xref: MA:0000183 xref: MAT:0000421 xref: MBA:567 xref: MESH:D013687 xref: MIAA:0000421 xref: neuronames:31 {source="BIRNLEX:1115"} xref: PBA:128011350 xref: SCTID:263353005 xref: TAO:0000079 xref: UMLS:C0039452 {source="BIRNLEX:1115"} xref: VHOG:0000283 xref: Wikipedia:Telencephalon xref: XAO:0000012 xref: ZFA:0000079 is_a: UBERON:0002616 ! regional part of brain relationship: develops_from UBERON:0014371 ! future telencephalon relationship: immediate_transformation_of UBERON:0014371 {source="Bgee:AN"} ! future telencephalon relationship: part_of UBERON:0001890 ! forebrain property_value: RO:0002171 UBERON:0002037 {source="ABA"} property_value: UBPROP:0000001 "Organ component of neuraxis that has as its parts the cerebral cortex, cerebral white matter, basal ganglia, septum and fornix, as well as subcortical gray and white matter structures[FMA:62000]." xsd:string {source="FMA:62000"} property_value: UBPROP:0000001 "Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010479", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The anterior and dorsal forebrain neuromere, includes the olfactory bulb. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000079", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from presumptive telencephalon (TAO:0000571)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000079", ontology="TAO"} property_value: UBPROP:0000003 "From an evolutionary standpoint, the telencephalon is the most recent brain structure: the amphioxus does not have this structure as a morphological entity. Overt telencephalon is present in the hagfish and lamprey to receive numerous input fibers from various parts of the CNS, similar to gnathostomes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000283", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y, Uchida K, Rijli FM and Kuratani S, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "cerebral" xsd:string property_value: UBPROP:0000007 "telencephalic" xsd:string property_value: UBPROP:0000007 "telenencephalic" xsd:string property_value: UBPROP:0000008 "dolphins are the only species (other than humans) to have cerebra accounting for as much as 2 percent of their body weight." xsd:string {source="Wikipedia:Telencephalon#Variation_among_species"} property_value: UBPROP:0000008 "In mammals the cortex covers almost the whole of the cerebral hemispheres." xsd:string {source="Wikipedia:Telencephalon#Variation_among_species"} property_value: UBPROP:0000008 "In ray-finned fishes and most pronounced in teleosts the roof plate of the embryonic telencephalon extends laterally with the effect that the paired alar plates forming the hemispheric walls roll out lateroventrally in a process called eversion. This is unlike the development in other vertebrate groups. [ZFA:0000079, ISBN:3764351209]" xsd:string property_value: UBPROP:0000008 "In ray-finned fishes the inner surfaces of the lateral and ventral regions of the cerebrum bulge up into the ventricles." xsd:string {source="Wikipedia:Telencephalon#Variation_among_species"} property_value: UBPROP:0000008 "In the amniotes, the cerebrum becomes increasingly large and complex. In reptiles, the paleopallium is much larger than in amphibians, and its growth has pushed the basal nuclei into the central regions of the cerebrum." xsd:string {source="Wikipedia:Telencephalon#Variation_among_species"} property_value: UBPROP:0000008 "In the most primitive living vertebrates, the hagfishes and lampreys, the cerebrum is a relatively simple structure receiving nerve impulses from the olfactory bulb." xsd:string {source="Wikipedia:Telencephalon#Variation_among_species"} property_value: UBPROP:0000008 "The cerebrum of birds has evolved along different lines to that of mammals, although they are similarly enlarged, by comparison with reptiles. However, this enlargement is largely due to the basal ganglia, with the other areas remaining relatively primitive in structure." xsd:string {source="Wikipedia:Telencephalon#Variation_among_species"} [Term] id: UBERON:0001895 name: metencephalon namespace: uberon def: "Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]." [https://github.com/obophenotype/uberon/issues/300, Wikipedia:Metencephalon] comment: the terms metencephalon and myelencephalon are only meaningful in mammals and birds[Neuroanatomy of the Zebrafish Brain]. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata and thus these are not distinguished in ZFA[ZFA]. subset: pheno_slim subset: uberon_slim synonym: "epencephalon" BROAD INCONSISTENT [ncithesaurus:Epencephalon] synonym: "epencephalon-2" EXACT [FMA:62003] xref: BAMS:Met xref: BIRNLEX:965 xref: BTO:0000673 xref: CALOHA:TS-2029 xref: DHBA:10655 xref: EHDAA2:0001149 xref: EHDAA:5498 xref: EMAPA:17071 xref: FMA:62003 xref: GAID:594 xref: HBA:4833 xref: MA:0000197 xref: MESH:D020540 xref: NCIT:C32741 xref: neuronames:543 {source="BIRNLEX:965"} xref: UMLS:C0376353 {source="BIRNLEX:965"} xref: UMLS:C1516904 {source="ncithesaurus:Epencephalon"} xref: VHOG:0000741 xref: Wikipedia:Metencephalon is_a: UBERON:0004733 ! segmental subdivision of hindbrain relationship: contributes_to_morphology_of UBERON:0002028 ! hindbrain relationship: develops_from UBERON:0010092 ! future metencephalon relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: immediate_transformation_of UBERON:0010092 {evidence="definitional"} ! future metencephalon property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI property_value: RO:0002174 NCBITaxon:7955 property_value: UBPROP:0000001 "Anterior part of the hindbrain ventral to the cerebellum[BIRNLEX:965]." xsd:string {source="BIRNLEX:965"} property_value: UBPROP:0000001 "The anterior of two brain vesicles formed by specialization of the rhombencephalon in the developing embryo. It gives rise to cerebellum and pons. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000741", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/metencephalon"} property_value: UBPROP:0000003 "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000741", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.381-382, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001896 name: medulla oblongata namespace: uberon def: "Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]." [FMA:62004, GO:0021550, Wikipedia:Bone_marrow_of_ovary_oblongata] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bulb" BROAD [] synonym: "bulbus" EXACT LATIN [FMA:62004, FMA:TA] synonym: "medulla" BROAD [ABA:MY] synonym: "medulla oblonzata" RELATED LATIN [Wikipedia:Medulla_oblongata] synonym: "metepencephalon" RELATED [FMA:62004] xref: AAO:0010486 xref: BAMS:Md xref: BAMS:MY xref: BIRNLEX:957 xref: BM:Me xref: BTO:0000041 xref: CALOHA:TS-0607 xref: DMBA:17352 xref: EFO:0000924 xref: EHDAA2:0001088 xref: EHDAA:7588 xref: EMAPA:17550 xref: EV:0100275 xref: FMA:62004 xref: GAID:590 xref: MA:0000206 xref: MAT:0000111 xref: MAT:0000367 xref: MBA:354 xref: MESH:D008526 xref: MIAA:0000111 xref: NCIT:C12442 xref: neuronames:698 {source="BIRNLEX:957"} xref: SCTID:279104005 xref: TAO:0000545 xref: UMLS:C0025148 {source="ncithesaurus:Medulla_Oblongata", source="BIRNLEX:957"} xref: UMLS:C1269575 {source="BIRNLEX:957"} xref: VHOG:0000181 xref: Wikipedia:Bone_marrow_of_ovary_oblongata xref: XAO:0003100 xref: ZFA:0000545 is_a: UBERON:0000064 ! organ part is_a: UBERON:0004121 ! ectoderm-derived structure relationship: capable_of GO:0002027 ! regulation of heart rate relationship: capable_of GO:0043576 ! regulation of respiratory gaseous exchange relationship: capable_of GO:0044058 ! regulation of digestive system process relationship: part_of UBERON:0002298 ! brainstem relationship: part_of UBERON:0005290 ! myelencephalon property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6b/Illu_pituitary_pineal_glands.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Posterior portion of the hindbrain which controls respiration, heartbeat, digestion, and swallowing as well as some locomotor responses.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010486", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The posterior region of the brain that is continuous with the spinal cord. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-17, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000181", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "Classical anatomical studies subdivided the vertebrate rhombencephalon into pons and medulla oblongata. (...) The medulla oblongata appears therefore as a tagma, that is, a group of segmental units (pseudorhombomeres, in this case) sharing some morphological and molecular characteristics, and in some aspects different from the segmental units present in adjoining brain regions, pons and spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000181", ontology="VHOG", source="DOI:10.1016/j.ydbio.2008.08.017 Marin F, Aroca P, Puelles L, Hox gene colinear expression in the avian medulla oblongata is correlated with pseudorhombomeric domains. Developmental Biology (2008)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001901 name: epithelium of trachea namespace: uberon alt_id: UBERON:0003227 def: "The epithelial lining of the trachea which contains numerous ciliated cells." [ISBN:0-397-51047-0, MGI:cwg, MP:0002285] subset: human_reference_atlas subset: pheno_slim synonym: "epithelial tissue of trachea" EXACT [OBOL:automatic] synonym: "epithelial tissue of windpipe" EXACT [OBOL:automatic] synonym: "epithelium of windpipe" EXACT [OBOL:automatic] synonym: "trachea epithelial tissue" EXACT [OBOL:automatic] synonym: "trachea epithelium" EXACT [] synonym: "tracheal epithelium" EXACT [] synonym: "windpipe epithelial tissue" EXACT [OBOL:automatic] synonym: "windpipe epithelium" EXACT [OBOL:automatic] xref: BTO:0001389 xref: CALOHA:TS-1061 xref: EHDAA2:0002069 xref: EHDAA:5007 xref: EMAPA:16855 xref: EMAPA:18409 xref: FMA:62015 xref: MA:0001862 xref: NCIT:C33797 xref: UMLS:C1179002 {source="ncithesaurus:Tracheal_Epithelium"} xref: VHOG:0001045 is_a: UBERON:0008397 ! tracheobronchial epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003126 ! trachea relationship: contributes_to_morphology_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0003258 ! endoderm of foregut relationship: part_of UBERON:0003126 ! trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001902 name: epithelium of small intestine namespace: uberon def: "An epithelium that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "epithelial tissue of small bowel" EXACT [OBOL:automatic] synonym: "epithelial tissue of small intestine" EXACT [OBOL:automatic] synonym: "epithelium of small bowel" EXACT [OBOL:automatic] synonym: "mid intestine epithelium" EXACT [ZFA:0005127] synonym: "small bowel epithelial tissue" EXACT [OBOL:automatic] synonym: "small bowel epithelium" EXACT [OBOL:automatic] synonym: "small intestinal epithelium" EXACT [] synonym: "small intestine epithelial tissue" EXACT [OBOL:automatic] synonym: "small intestine epithelium" EXACT [] xref: BTO:0001258 xref: CALOHA:TS-2104 xref: EMAPA:35778 xref: FMA:62017 xref: MA:0001553 xref: SCTID:45480009 xref: TAO:0005127 xref: ZFA:0005127 is_a: UBERON:0001277 ! intestinal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002108 ! small intestine relationship: has_part CL:0000164 {source="FMA"} ! enteroendocrine cell relationship: part_of UBERON:0001204 ! mucosa of small intestine property_value: UBPROP:0000001 "Intestinal epithelium which lines the lumen of the mid intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005127", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001915 name: endothelium of capillary namespace: uberon def: "An endothelium that is part of a capillary [Automatically generated definition]." [OBOL:automatic] synonym: "blood capillary endothelium" EXACT [OBOL:automatic] synonym: "capillary endothelium" EXACT [] synonym: "capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel" EXACT [OBOL:automatic] xref: BTO:0004954 xref: CALOHA:TS-0112 xref: EMAPA:36292 xref: FMA:62114 xref: MA:0000711 xref: NCIT:C49215 xref: UMLS:C0006904 {source="ncithesaurus:Capillary_Endothelium"} is_a: UBERON:0008339 ! microvascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001982 ! capillary relationship: part_of UBERON:0001982 ! capillary [Term] id: UBERON:0001916 name: endothelium of arteriole namespace: uberon def: "An endothelium that is part of an arteriole [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "arteriole endothelium" EXACT [] xref: EMAPA:36286 xref: FMA:62115 xref: MA:0000705 xref: NCIT:C49192 xref: UMLS:C1179024 {source="ncithesaurus:Arteriole_Endothelium"} is_a: UBERON:0004700 ! arterial system endothelium is_a: UBERON:0008339 ! microvascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001980 ! arteriole relationship: part_of UBERON:0001980 ! arteriole property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001917 name: endothelium of artery namespace: uberon def: "An endothelium that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "arterial endothelium" EXACT [] synonym: "artery endothelium" EXACT [] xref: AAO:0011013 xref: BTO:0004757 xref: EMAPA:35148 xref: FMA:62116 xref: MA:0000707 xref: NCIT:C49194 xref: UMLS:C1179025 {source="ncithesaurus:Artery_Endothelium"} xref: VHOG:0001215 xref: XAO:0000357 is_a: UBERON:0003915 ! endothelial tube is_a: UBERON:0004638 ! blood vessel endothelium is_a: UBERON:0004700 ! arterial system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0001637 ! artery property_value: UBPROP:0000001 "The endothelium is the thin layer of cells that lines the interior surface of blood vessels, forming an interface between circulating blood in the lumen and the rest of the vessel wall.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011013", ontology="AAO", source="XAO:curator"} property_value: UBPROP:0000003 "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001215", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001918 name: endothelium of venule namespace: uberon def: "An endothelium that is part of a venule [Automatically generated definition]." [OBOL:automatic] synonym: "venule endothelium" EXACT [] xref: EMAPA:36290 xref: FMA:62117 xref: MA:0000716 xref: NCIT:C49319 xref: UMLS:C1179026 {source="ncithesaurus:Venule_Endothelium"} is_a: UBERON:0004701 ! venous system endothelium is_a: UBERON:0008339 ! microvascular endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001979 ! venule relationship: part_of UBERON:0001979 ! venule [Term] id: UBERON:0001919 name: endothelium of vein namespace: uberon def: "An endothelium that is part of a vein [Automatically generated definition]." [OBOL:automatic] synonym: "vein endothelium" EXACT [] synonym: "veinous endothelium" RELATED [VHOG:0001216] synonym: "venous endothelium" EXACT [] xref: AAO:0011110 xref: BTO:0004756 xref: EMAPA:36288 xref: FMA:62118 xref: MA:0000712 xref: NCIT:C49317 xref: UMLS:C1179027 {source="ncithesaurus:Vein_Endothelium"} xref: VHOG:0001216 xref: XAO:0000358 is_a: UBERON:0004638 ! blood vessel endothelium is_a: UBERON:0004701 ! venous system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001638 ! vein relationship: part_of UBERON:0001638 ! vein property_value: UBPROP:0000003 "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001216", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001943 name: midbrain tegmentum namespace: uberon def: "Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]." [FMA:FMA, ISBN:0471888893, Wikipedia:Midbrain_tegmentum] comment: 'tegmentum' is used generically for the ventral part of the brainstem (ISBN:0471888893). We use the label 'midbrain tegmentum' to denote the midbrain structure. In NIFSTD tegmentum is a composite structure and there is a separate class for midbrain tegmentum and pontine tegmentum subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mesencephalic tegmentum" RELATED [VHOG:0001367] synonym: "MTg" BROAD ABBREVIATION [BIRNLEX:1200, NIFSTD:NeuroNames_abbrevSource] synonym: "tegmentum" BROAD [ISBN:0471888893] synonym: "tegmentum mesencephali" EXACT LATIN [Wikipedia:Midbrain_tegmentum] synonym: "tegmentum mesencephalicum" RELATED LATIN [NeuroNames:491] synonym: "tegmentum of midbrain" EXACT [] xref: BAMS:MTg xref: BIRNLEX:1200 xref: BTO:0003388 xref: DHBA:12195 xref: EFO:0000921 xref: EHDAA2:0004475 xref: EMAPA:18215 xref: FMA:62393 xref: HBA:9002 xref: MA:0000212 xref: MAT:0000452 xref: neuronames:491 {source="BIRNLEX:1200"} xref: SCTID:362392007 xref: TAO:0000160 xref: UMLS:C0039441 {source="BIRNLEX:1200"} xref: VHOG:0001367 xref: Wikipedia:Midbrain_tegmentum xref: XAO:0004271 xref: ZFA:0000160 is_a: UBERON:0002616 ! regional part of brain relationship: develops_from UBERON:0010285 {source="ZFA"} ! midbrain basal plate relationship: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0002298 ! brainstem property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b6/Gray712.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Together, our results reveal a shared basic organization in the tegmental domains of the diencephalon and midbrain of developing lamprey, indicating early appearance of the domain in vertebrate phylogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001367", ontology="VHOG", source="DOI:10.1016/j.brainresbull.2005.05.001 Villar-Cheda B, Abalo XM, Anadon R, Rodicio MC, The tegmental proliferation region in the sea lamprey. Brain Research Bulletin (2005)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0001948 name: regional part of spinal cord namespace: uberon def: "A multi-tissue structure that is part of a spinal cord." [OBOL:automatic] subset: non_informative synonym: "spinal cord part" RELATED [] xref: BIRNLEX:1496 xref: NCIT:C33969 xref: SCTID:244437008 xref: UMLS:C1268166 {source="ncithesaurus:Spinal_Cord_Part"} is_a: UBERON:0000073 ! regional part of nervous system is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0001949 name: gingival epithelium namespace: uberon def: "A stratified squamous epithelium consisting of a basal layer; it is keratinized or parakeratinized[BTO]." [BTO:0004998] synonym: "epithelial tissue of gingiva" EXACT [OBOL:automatic] synonym: "epithelium of gingiva" EXACT [] synonym: "gingiva epithelial tissue" EXACT [OBOL:automatic] synonym: "gingiva epithelium" EXACT [OBOL:automatic] xref: BTO:0004998 xref: FMA:62423 xref: MA:0001576 xref: NCIT:C49239 xref: UMLS:C1179154 {source="ncithesaurus:Gingival_Epithelium"} is_a: UBERON:0002424 ! oral epithelium is_a: UBERON:0006915 ! stratified squamous epithelium is_a: UBERON:0035037 ! jaw epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001828 ! gingiva relationship: part_of UBERON:0001828 ! gingiva property_value: UBPROP:0000008 "In humans: 15% orthokeratinized, 75% parakeratinized, 10% non-keratinized; diurnal; decreased keratinization with age. Note that in FMA this is classified as keratinized squamous - this perhaps refers to the epithelium of the attached or free gingiva" xsd:string [Term] id: UBERON:0001950 name: neocortex namespace: uberon def: "An area of cerebral cortex defined on the basis of cytoarchitecture that have six layers. Starting from the cortical surface the layers are: molecular layer (I), external granular layer (II), external pyramidal layer (III), internal granular layer (IV), internal pyramidal layer (V), and multiform layer (VI). Neocortex is most prominent in the frontal lobe, the parietal lobe, the temporal lobe and the occipital lobe, less so in the cingulate gyrus, the parahippocampal gyrus and the insula. It is composed of two subdivisions: true isocortex and proisocortex (Carpenter-83)(NN)." [BIRNLEX:2547, OldNeuroNames:754] subset: pheno_slim subset: uberon_slim synonym: "cerebral neocortex" EXACT [] synonym: "homogenetic cortex" EXACT DEPRECATED [ISBN:0471888893] synonym: "homotypical cortex" EXACT [BIRNLEX:2547] synonym: "iso-cortex" RELATED [BAMS:iso-cortex] synonym: "isocortex" NARROW [BRAINSPAN:BRAINSPAN] synonym: "isocortex (sensu lato)" EXACT [FMA:62429] synonym: "neocortex (isocortex)" EXACT [DHBA:10160] synonym: "neopallial cortex" EXACT [] synonym: "neopallium" EXACT [] synonym: "nonolfactory cortex" RELATED [BTO:0000920] synonym: "nucleus hypoglossalis" RELATED LATIN [NeuroNames:757] xref: BAMS:ISO xref: BAMS:Iso-cortex xref: BAMS:NCX xref: BIRNLEX:2547 xref: BTO:0000920 xref: DHBA:10160 xref: EHDAA2:0004662 xref: EMAPA:32842 xref: EMAPA:35589 xref: FMA:62429 xref: GAID:677 xref: MA:0002754 xref: MBA:315 xref: MESH:D019579 xref: neuronames:757 {source="BIRNLEX:2547"} xref: PBA:294021746 xref: UMLS:C0175173 {source="BIRNLEX:2547"} xref: Wikipedia:Neocortex is_a: UBERON:0002616 ! regional part of brain relationship: contributes_to_morphology_of UBERON:0000956 ! cerebral cortex relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: part_of UBERON:0000956 ! cerebral cortex property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Neocortex.jpg" xsd:anyURI property_value: RO:0002171 UBERON:0002264 {source="ABA"} property_value: UBPROP:0000003 "The 6-layer neocortex is well conserved in all extant mammals, but not present in birds or reptils" xsd:string {source="PMID:23027930"} [Term] id: UBERON:0001951 name: epithelium of nasopharynx namespace: uberon alt_id: UBERON:0003237 def: "An epithelium that is part of a nasopharynx [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "epithelial tissue of nasopharynx" EXACT [OBOL:automatic] synonym: "epithelial tissue of rhinopharynx" EXACT [OBOL:automatic] synonym: "epithelium of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "epithelium of rhinopharynx" EXACT [OBOL:automatic] synonym: "nasal part of pharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "nasal part of pharynx epithelium" EXACT [OBOL:automatic] synonym: "nasopharyngeal epithelium" RELATED [BTO:0004480] synonym: "nasopharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "nasopharynx epithelium" EXACT [] synonym: "rhinopharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "rhinopharynx epithelium" EXACT [OBOL:automatic] xref: BTO:0004480 xref: CALOHA:TS-0662 xref: EHDAA2:0001241 xref: EHDAA:7090 xref: EMAPA:17672 xref: FMA:62452 xref: MA:0001865 xref: NCIT:C49263 xref: UMLS:C1179157 {source="ncithesaurus:Nasopharynx_Epithelium"} xref: VHOG:0001038 is_a: UBERON:0003351 ! pharyngeal epithelium is_a: UBERON:0004814 ! upper respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0003929 {source="EHDAA2"} ! digestive tract epithelium [Term] id: UBERON:0001956 name: cartilage of bronchus namespace: uberon def: "The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]." [MP:0010988] subset: human_reference_atlas subset: pheno_slim synonym: "bronchi cartilage" EXACT [OBOL:automatic] synonym: "bronchial cartilage" EXACT [] synonym: "bronchial cartilage ring" EXACT [MP:0010988] synonym: "bronchial trunk cartilage" EXACT [OBOL:automatic] synonym: "bronchus cartilage" EXACT [] synonym: "cartilage of bronchi" EXACT [OBOL:automatic] synonym: "cartilage of bronchial trunk" EXACT [OBOL:automatic] synonym: "cartilagines bronchiales" EXACT PLURAL [] xref: EMAPA:35192 xref: FMA:62649 xref: MA:0001835 xref: NCIT:C49209 xref: SCTID:278980009 xref: UMLS:C0225604 {source="ncithesaurus:Bronchus_Cartilage"} is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0003603 ! lower respiratory tract cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0002185 ! bronchus relationship: composed_primarily_of UBERON:0001994 {source="MP"} ! hyaline cartilage tissue relationship: contributes_to_morphology_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 ! bronchus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001957 name: submucosa of bronchus namespace: uberon def: "A submucosa that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi submucosa" EXACT [OBOL:automatic] synonym: "bronchial submucosa" EXACT [] synonym: "bronchial trunk submucosa" EXACT [OBOL:automatic] synonym: "bronchus submucosa" EXACT [] synonym: "submucosa of bronchi" EXACT [OBOL:automatic] synonym: "submucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "submucous layer of bronchi" RELATED [BTO:0002108] synonym: "tela submucosa bronchi" EXACT LATIN [FMA:62653, FMA:TA] xref: BTO:0002108 xref: EMAPA:37449 {source="MA:th"} xref: FMA:62653 xref: MA:0001837 xref: NCIT:C49214 xref: SCTID:85546005 xref: UMLS:C0225601 {source="ncithesaurus:Bronchus_Submucosa"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004777 ! respiratory system submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 ! bronchus [Term] id: UBERON:0001958 name: terminal bronchiole epithelium namespace: uberon def: "An epithelium that lines a terminal bronchiole." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "bronchiolus terminalis epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "epithelial tissue of terminal bronchiole" EXACT [OBOL:automatic] synonym: "epithelium of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "epithelium of terminal bronchiole" EXACT [FMA:62794] synonym: "terminal bronchiole epithelial tissue" EXACT [OBOL:automatic] synonym: "terminal bronchiole epithelium" EXACT [] xref: EMAPA:36283 xref: FMA:62794 xref: MA:0001774 xref: NCIT:C33755 xref: UMLS:C1179400 {source="ncithesaurus:Terminal_Bronchiole_Epithelium"} is_a: UBERON:0002051 ! epithelium of bronchiole intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002187 ! terminal bronchiole relationship: has_part CL:0000158 {source="FMA"} ! club cell relationship: part_of UBERON:0002187 ! terminal bronchiole property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "A pseudostratified epithelium, containing basal cells, stem cells of the airway, submucosal glands and cartilage rings, is limited to the trachea and large lobar airways in the mouse (Morrisey and Hogan, 2010). This more complex epithelium extends to terminal bronchioles in the human[DOI:10.1242/dev.115469]" xsd:string [Term] id: UBERON:0001968 name: semen namespace: uberon def: "Organism substance that is composed of sperm cells suspended in seminal fluid." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "ejaculate" RELATED [] synonym: "sperm" RELATED [BTO:0001230] xref: BTO:0001230 xref: CALOHA:TS-0917 xref: EMAPA:31488 xref: FMA:62966 xref: GAID:1169 xref: MA:0002522 xref: MESH:D012661 xref: NCIT:C13277 xref: NCIT:C13713 xref: UMLS:C1518159 {source="ncithesaurus:Male_Genital_System_Fluid_or_Secretion"} xref: UMLS:C2756969 {source="ncithesaurus:Semen"} xref: Wikipedia:Semen is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000463 ! organism substance relationship: has_part CL:0000019 ! sperm relationship: has_part UBERON:0006530 ! seminal fluid relationship: output_of GO:0042713 ! sperm ejaculation property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/40/Human_semen_in_petri_dish2.jpg" xsd:anyURI property_value: UBPROP:0000007 "seminal" xsd:string property_value: UBPROP:0000008 "Note that in this ontology, semen is defined as the sum of sperm and seminal fluid, where seminal fluid is defined in taxonomically generic way (see comments for UBERON:0006530)." xsd:string [Term] id: UBERON:0001969 name: blood plasma namespace: uberon def: "The liquid component of blood, in which erythrocytes are suspended." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "blood plasm" EXACT [] synonym: "plasma" BROAD [MA:0002501] synonym: "portion of blood plasma" EXACT [] synonym: "portion of plasma" BROAD [FMA:62970] xref: BTO:0000131 xref: CALOHA:TS-0800 xref: EFO:0001905 xref: EMAPA:35690 xref: FMA:62970 xref: GAID:1178 xref: MA:0002501 xref: MAT:0000052 xref: MESH:D010949 xref: MIAA:0000052 xref: NCIT:C13356 xref: UMLS:C0032105 {source="ncithesaurus:Plasma"} xref: Wikipedia:Blood_plasma is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000179 ! haemolymphatic fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: has_part GO:0005577 ! fibrinogen complex intersection_of: has_quality PATO:0001548 ! quality of a liquid intersection_of: part_of UBERON:0000178 ! blood intersection_of: surrounds CL:0000232 ! erythrocyte relationship: has_part GO:0005577 ! fibrinogen complex relationship: part_of UBERON:0000178 ! blood relationship: surrounds CL:0000232 ! erythrocyte [Term] id: UBERON:0001970 name: bile namespace: uberon def: "Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium." [DOI:10.1002/cphy.c120027, Wikipedia:Bile] subset: pheno_slim subset: uberon_slim synonym: "fel" RELATED [BTO:0000121] synonym: "gall" RELATED [BTO:0000121] xref: BTO:0000121 xref: CALOHA:TS-1172 xref: ENVO:02000023 xref: FMA:62971 xref: GAID:1157 xref: galen:Bile xref: MA:0002513 xref: MESH:D001646 xref: NCIT:C13192 xref: UMLS:C0005388 {source="ncithesaurus:Bile"} xref: Wikipedia:Bile xref: ZFA:0005857 is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0002107 ! liver relationship: capable_of_part_of GO:0007586 ! digestion relationship: has_part CHEBI:16990 {composition="0.3% in humans"} ! bilirubin IXalpha relationship: has_part CHEBI:22868 ! bile salt relationship: has_part CHEBI:36277 ! bile acid salt relationship: has_quality PATO:0001735 ! liquid configuration relationship: produced_by UBERON:0002107 ! liver property_value: UBPROP:0000008 "In many species, bile is stored in the gallbladder and upon eating is discharged into the duodenum." xsd:string property_value: UBPROP:0000009 "aids the process of digestion of lipids in the small intestine" xsd:string property_value: UBPROP:0000009 "bile salts function to emulsify dietary fats and facilitate their intestinal absorption" xsd:string property_value: UBPROP:0000009 "elimination of cholesterol" xsd:string property_value: UBPROP:0000009 "major excretory route for potentially harmful exogenous lipophilic substances" xsd:string property_value: UBPROP:0000009 "many hormones and pheromones are excreted in bile, and contribute to growth and development of the intestine in some species and provide attractants for the weaning of non-human vertebrates" xsd:string property_value: UBPROP:0000009 "protects the organism from enteric infections by excreting immune globulin A (IgA), inflammatory cytokines, and stimulating the innate immune system in the intestine" xsd:string [Term] id: UBERON:0001971 name: gastric juice namespace: uberon def: "." [Wikipedia:Gastric_juice] subset: pheno_slim subset: uberon_slim synonym: "stomach secretion" EXACT [] synonym: "succus gastricus" RELATED [BTO:0000501] xref: BTO:0000501 xref: FMA:62972 xref: GAID:1160 xref: galen:GastricJuice xref: MA:0002519 xref: MESH:D005750 xref: NCIT:C32661 xref: UMLS:C0017133 {source="ncithesaurus:Gastric_Secretion"} xref: Wikipedia:Gastric_juice is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0011953 ! stomach glandular region relationship: produced_by UBERON:0011953 ! stomach glandular region [Term] id: UBERON:0001972 name: submucosa of esophagus namespace: uberon def: "A submucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal submucosa" EXACT [] synonym: "esophagus submucosa" EXACT [] synonym: "gullet submucosa" EXACT [OBOL:automatic] synonym: "oesophagus submucosa" EXACT [OBOL:automatic] synonym: "submucosa of esophagus" EXACT [] synonym: "submucosa of gullet" EXACT [OBOL:automatic] synonym: "submucosa of oesophagus" EXACT [OBOL:automatic] synonym: "submucous layer of esophagus" RELATED [BTO:0002109] synonym: "tela submucosa (oesophagus)" EXACT LATIN [FMA:62997, FMA:TA] synonym: "tela submucosa esophagi" EXACT LATIN [BTO:0002109] synonym: "tela submucosa oesophageae" EXACT LATIN [FMA:62997, FMA:TA] synonym: "tela submucosa oesophagi" RELATED [BTO:0002109] synonym: "tela submucosa of esophagus" EXACT [] xref: BTO:0002109 xref: EMAPA:35325 xref: FMA:62997 xref: MA:0002724 xref: SCTID:362128009 is_a: UBERON:0018257 ! submucosa of digestive tract intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 ! wall of esophagus [Term] id: UBERON:0001974 name: lamina propria of esophagus namespace: uberon def: "A lamina propria that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal lamina propria" RELATED [EMAPA:26987] synonym: "esophagus lamina propria" EXACT [] synonym: "esophagus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "esophagus lamina propria mucosae" EXACT [OBOL:automatic] synonym: "gullet lamina propria" EXACT [OBOL:automatic] synonym: "gullet lamina propria mucosa" EXACT [OBOL:automatic] synonym: "gullet lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of esophagus" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of gullet" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of esophagus" EXACT [] synonym: "lamina propria mucosae of gullet" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of oesophagus" EXACT [OBOL:automatic] synonym: "lamina propria of gullet" EXACT [OBOL:automatic] synonym: "lamina propria of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus lamina propria" RELATED [] synonym: "oesophagus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "oesophagus lamina propria mucosae" EXACT [OBOL:automatic] xref: EMAPA:26987 xref: FMA:63050 xref: MA:0001568 xref: NCIT:C49223 xref: UMLS:C1707949 {source="ncithesaurus:Esophageal_Lamina_Propria"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0002469 {source="FMA"} ! esophagus mucosa [Term] id: UBERON:0001975 name: serosa of esophagus namespace: uberon def: "A serous membrane that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophagus serosa" EXACT [] synonym: "esophagus serous membrane" EXACT [OBOL:automatic] synonym: "gullet serosa" EXACT [OBOL:automatic] synonym: "gullet serous membrane" EXACT [OBOL:automatic] synonym: "oesophagus serosa" RELATED [] synonym: "oesophagus serous membrane" EXACT [OBOL:automatic] synonym: "serosa of abdominal part of esophagus" EXACT [] synonym: "serosa of gullet" EXACT [OBOL:automatic] synonym: "serosa of oesophagus" EXACT [] synonym: "serous coat of oesophagus" EXACT [] synonym: "serous membrane of esophagus" EXACT [OBOL:automatic] synonym: "serous membrane of gullet" EXACT [OBOL:automatic] synonym: "serous membrane of oesophagus" EXACT [OBOL:automatic] synonym: "tunica serosa oesophageae" EXACT LATIN [FMA:63057, FMA:TA] xref: EMAPA:35322 xref: FMA:63057 xref: MA:0001571 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 ! wall of esophagus [Term] id: UBERON:0001976 name: epithelium of esophagus namespace: uberon def: "The epithelial layer that lines the luminal space of the esophagus." [ISBN:0-683-40008-8, MP:0000468] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "epithelial tissue of esophagus" EXACT [OBOL:automatic] synonym: "epithelial tissue of gullet" EXACT [OBOL:automatic] synonym: "epithelial tissue of oesophagus" EXACT [OBOL:automatic] synonym: "epithelium of gullet" EXACT [OBOL:automatic] synonym: "epithelium of oesophagus" EXACT [OBOL:automatic] synonym: "esophageal epithelium" EXACT [] synonym: "esophagus epithelial tissue" EXACT [OBOL:automatic] synonym: "esophagus epithelium" EXACT [] synonym: "gullet epithelial tissue" EXACT [OBOL:automatic] synonym: "gullet epithelium" EXACT [OBOL:automatic] synonym: "oesophagus epithelial tissue" EXACT [OBOL:automatic] synonym: "oesophagus epithelium" RELATED [] xref: BTO:0001578 xref: CALOHA:TS-0698 xref: EFO:0003041 xref: EHDAA2:0001287 xref: EMAPA:16835 xref: FMA:63063 xref: MA:0001565 xref: NCIT:C49221 xref: TAO:0001499 xref: UMLS:C1179544 {source="ncithesaurus:Esophageal_Epithelium"} xref: ZFA:0001499 is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001043 ! esophagus relationship: contributes_to_morphology_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0002469 {source="FMA"} ! esophagus mucosa property_value: editor_note "TODO check epithelium types: in FMA: Nonkeratinizing stratified squamous epithelium; mouse has basal and squamous subtypes; in ZFA it is columnar" xsd:string property_value: UBPROP:0000001 "Simple columnar epithelium that lines the esophagus. Chen et al, 2007.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001499", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001978 name: parenchyma of pancreas namespace: uberon subset: human_reference_atlas synonym: "pancreas parenchyma" EXACT [] synonym: "pancreatic parenchyma" EXACT [] xref: EMAPA:32925 xref: FMA:63120 xref: MA:0000724 xref: SCTID:371401008 xref: VHOG:0001430 is_a: UBERON:0000353 ! parenchyma intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001979 name: venule namespace: uberon def: "One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins." [MESH:A07.231.432.952, MP:0004125] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "venula" RELATED LATIN [Wikipedia:Venule] xref: BTO:0002626 xref: EMAPA:35917 xref: FMA:63130 xref: MA:0000071 xref: MESH:D014699 xref: NCIT:C12818 xref: SCTID:341687009 xref: TAO:0005315 xref: UMLS:C0042520 {source="ncithesaurus:Venule"} xref: VHOG:0001765 xref: Wikipedia:Venule xref: ZFA:0005315 is_a: UBERON:0003920 ! venous blood vessel is_a: UBERON:8410081 ! blood microvessel relationship: connects UBERON:0001638 ! vein relationship: connects UBERON:0001982 ! capillary property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Multi-tissue structure part of the blood vasculature formed by the anastomosis of capillaries. Venules carry blood toward the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005315", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0001980 name: arteriole namespace: uberon def: "The smallest division of the artery located between the muscular arteries and the capillaries[GO]." [GO:0014830] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arteriola" RELATED LATIN [Wikipedia:Arteriole] xref: AAO:0010253 xref: BTO:0001997 xref: EMAPA:35146 xref: FMA:63182 xref: MA:0000063 xref: MESH:D001160 xref: NCIT:C12672 xref: SCTID:337724002 xref: TAO:0002138 xref: UMLS:C0003847 {source="ncithesaurus:Arteriole"} xref: VHOG:0001763 xref: Wikipedia:Arteriole xref: ZFA:0005255 is_a: UBERON:0003509 {source="MA"} ! arterial blood vessel is_a: UBERON:8410081 ! blood microvessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: connects UBERON:0001637 ! artery intersection_of: connects UBERON:0001982 ! capillary relationship: connects UBERON:0001637 ! artery relationship: connects UBERON:0001982 ! capillary relationship: contributes_to_morphology_of UBERON:0001637 ! artery property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/da/Illu_capillary.jpg" xsd:anyURI property_value: UBPROP:0000001 "Multi-tissue structure part of the blood vasculature, feeds into capillaries. Arterioles carry blood away from the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002138", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Small, terminal branch of an artery which generally connects to capillaries.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010253", ontology="AAO", source="AAO:BJB"} [Term] id: UBERON:0001981 name: blood vessel namespace: uberon def: "A vessel through which blood circulates in the body." [BTO:0001102, Wikipedia:Blood_vessel] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "region of vascular tree organ" EXACT [FMA:50722] synonym: "vas sanguineum" RELATED LATIN [Wikipedia:Blood_vessel] synonym: "vascular element" BROAD [EMAPA:35993] synonym: "vascular tree organ region" EXACT [FMA:50722] xref: AAO:0011004 xref: AEO:0000207 xref: BTO:0001102 xref: CALOHA:TS-0080 xref: EFO:0000817 xref: EHDAA2:0003252 xref: EHDAA:240 xref: EMAPA:32743 xref: EMAPA:35993 xref: FMA:50722 xref: FMA:63183 xref: GAID:169 xref: MA:0000060 xref: MAT:0000393 xref: MESH:D001808 xref: NCIT:C12679 xref: NLXANAT:090901 xref: SCTID:361097006 xref: TAO:0002137 xref: UMLS:C0005847 {source="ncithesaurus:Blood_Vessel"} xref: VHOG:0001250 xref: Wikipedia:Blood_vessel xref: XAO:0001011 xref: ZFA:0005314 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000055 ! vessel is_a: UBERON:0004120 ! mesoderm-derived structure relationship: capable_of_part_of GO:0008015 ! blood circulation relationship: channel_for UBERON:0000178 ! blood relationship: develops_from UBERON:0004872 ! splanchnic layer of lateral plate mesoderm relationship: develops_from UBERON:0006965 {source="GO:0072360"} ! vascular cord relationship: has_part CL:0000071 {source="AEO"} ! blood vessel endothelial cell relationship: has_part UBERON:0007500 {source="EHDAA2"} ! epithelial tube open at both ends relationship: has_quality PATO:0002045 ! dendritic relationship: part_of UBERON:0004537 ! blood vasculature property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI property_value: editor_note "consider adopting the EMAPA superclass 'vascular element', which includes microvasculature (e.g. capillaries), vascular plexus" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Any of the vessels through which blood circulates in the body. [XAO:0001011_][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001250", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Any of the vessels through which blood circulates in the body.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011004", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001250", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "annelids have blood vessels, but this class is not applicable to annelids." xsd:string property_value: UBPROP:0000012 "FMA:63183 Blood vessel is categorized as 'general anatomical term'. Suggestion to map to region of vascular tree from Terry H at JAX" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0001982 name: capillary namespace: uberon def: "Any of the smallest blood vessels connecting arterioles with venules." [https://github.com/obophenotype/uberon/issues/137, ISBN:0073040584, Wikipedia:Capillary] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "blood capillary" EXACT [] synonym: "capillary vessel" EXACT [] xref: AAO:0010252 xref: BTO:0002045 xref: CALOHA:TS-2006 xref: EFO:0001906 xref: EMAPA:35198 xref: EV:0100035 xref: FMA:63194 xref: MA:0000065 xref: MESH:D002196 xref: NCIT:C12685 xref: NLXANAT:090902 xref: TAO:0005250 xref: UMLS:C0935624 {source="ncithesaurus:Capillary"} xref: VHOG:0001253 xref: Wikipedia:Capillary xref: XAO:0000116 xref: ZFA:0005250 is_a: UBERON:8410081 ! blood microvessel intersection_of: UBERON:8410081 ! blood microvessel intersection_of: connects UBERON:0001979 ! venule intersection_of: connects UBERON:0001980 ! arteriole relationship: connects UBERON:0001979 ! venule relationship: connects UBERON:0001980 ! arteriole property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2f/A_red_blood_cell_in_a_capillary,_pancreatic_tissue_-_TEM.jpg" xsd:anyURI property_value: editor_note "not all sources agree capillary is a blood vessel - consider adopting EMAPA superclass of vascular element" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2186" xsd:string property_value: UBPROP:0000001 "Any of the tiny blood vessels connecting the arterioles to the venules.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010252", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001253", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2006)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000010 "capillaries lack tunica media and tunica adventitia; only the endothelial wall of the tunica intima belongs" xsd:string [Term] id: UBERON:0001985 name: corneal endothelium namespace: uberon def: "A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]." [Wikipedia:Corneal_endothelium] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cornea endothelium" EXACT [OBOL:automatic] synonym: "endothelium of cornea" EXACT [OBOL:automatic] synonym: "epithelium posterius corneae" RELATED LATIN [Wikipedia:Corneal_endothelium] xref: CALOHA:TS-0172 xref: EMAPA:35935 xref: FMA:63882 xref: GAID:891 xref: MA:0001242 xref: MESH:D004728 xref: NCIT:C12707 xref: SCTID:368827009 xref: TAO:0002186 xref: UMLS:C0014259 {source="ncithesaurus:Corneal_Endothelium"} xref: Wikipedia:Corneal_endothelium xref: ZFA:0001687 is_a: UBERON:0001986 ! endothelium is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000964 ! cornea relationship: adjacent_to UBERON:0001766 ! anterior chamber of eyeball relationship: contributes_to_morphology_of UBERON:0000964 ! cornea relationship: part_of UBERON:0000964 ! cornea property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Gray871.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0001986 name: endothelium namespace: uberon def: "A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]." [FMA:63916, https://github.com/obophenotype/uberon/issues/225, MESH:A10.272.491] comment: The term 'endothelium' has been either restricted to the continuous cell layer of the vertebrates, as we are assuming here, or applied to all the cells able to adhere to the luminal surface of the vascular basement membrane (Casley-Smith 1980) subset: efo_slim subset: human_reference_atlas subset: uberon_slim xref: BTO:0000393 xref: CALOHA:TS-0278 xref: EFO:0002548 xref: FMA:63916 xref: GAID:520 xref: galen:Endothelium xref: MESH:D004727 xref: NCIT:C12481 xref: SCTID:27168002 xref: UMLS:C0014257 {source="ncithesaurus:Endothelium"} is_a: UBERON:0000487 {source="FMA-text-def", source="https://github.com/obophenotype/uberon/issues/225"} ! simple squamous epithelium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: composed_primarily_of CL:0000115 ! endothelial cell relationship: composed_primarily_of CL:0000115 ! endothelial cell relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "endothelial" xsd:string [Term] id: UBERON:0001987 name: placenta namespace: uberon def: "Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/06placenta.htm, Wikipedia:Placenta] comment: Marsupials possess only a rudimentary yolk-type placenta, with reduced nutrient and oxygen exchanging capabilities. subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "allantoic placenta" EXACT [ISBN:0073040584] synonym: "eutherian placenta" EXACT [] xref: BTO:0001078 xref: CALOHA:TS-0799 xref: EFO:0001407 xref: EMAPA:35689 xref: EV:0100119 xref: FMA:63934 xref: GAID:379 xref: MA:0000386 xref: MAT:0000279 xref: MESH:D010920 xref: MIAA:0000279 xref: NCIT:C13272 xref: SCTID:181455002 xref: UMLS:C0032043 {source="ncithesaurus:Placenta"} xref: VHOG:0001266 xref: Wikipedia:Placenta is_a: UBERON:0000062 ! organ is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: develops_from UBERON:0000995 {source="ISBN:0073040584"} ! uterus relationship: develops_from UBERON:0003124 {source="Wikipedia"} ! chorion membrane relationship: develops_from UBERON:0004340 {source="ISBN:0073040584"} ! allantois relationship: only_in_taxon NCBITaxon:32525 {source="https://github.com/obophenotype/uberon/issues/1376"} ! Theria relationship: part_of UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0016887 ! entire extraembryonic component property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/66/Placenta.jpg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f1/Placenta.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Phylogenetic analyses of the concatenated data set using maximum parsimony, maximum likelihood and distance based (neighbour joining) methods all converged on a nearly identical, well supported topology defining four principal eutherian lineages. The results affirm monophyly of traditional placental orders (except Artiodactyla and Insectivora), and also support some previously proposed, as well as new, superordinal clades.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001266", ontology="VHOG", source="DOI:10.1038/35054550 Murphy WJ, Eizirik E, Johnson WE, Zhang YP, Ryder OA, O'Brien SJ, Molecular phylogenetics and the origins of placental mammals. Nature (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "placental" xsd:string property_value: UBPROP:0000008 "Eutherians: In eutherians, the chorioallantoic membrane of the fetus establishes intimate contact with the adjacent vascular wall of the mother's uterus to produce the placenta, a composite structure formed in part from tissues of the fetus and in part from tissues of the mother [ISBN:0073040584 (Vertebrates, Kardong)]. TODO - is taxon restriction too strict, even if we restrict def to allantoic placenta? - WP says: also found in some snakes and lizards with varying levels of development up to mammalian levels. Pough et al. 1992. Herpetology: Third Edition. Pearson Prentice Hall:Pearson Education, Inc., 2002. // See also: DOI:10.1002/jmor.11011" xsd:string [Term] id: UBERON:0001988 name: feces namespace: uberon def: "Portion of semisolid bodily waste discharged through the anus[MW,modified]." [http://www.merriam-webster.com/dictionary/feces, Wikipedia:Feces] subset: pheno_slim subset: uberon_slim synonym: "cow dung" NARROW [Wikipedia:Cow_dung] synonym: "cow pat" NARROW [Wikipedia:Cow_dung] synonym: "droppings" RELATED [] synonym: "dung" NARROW [] synonym: "excrement" RELATED [BTO:0000440] synonym: "excreta" BROAD [] synonym: "faeces" EXACT [] synonym: "fecal material" EXACT [] synonym: "fecal matter" EXACT [] synonym: "fewmet" NARROW [Wikipedia:Fewmet] synonym: "frass" NARROW [Wikipedia:Frass] synonym: "guano" NARROW [Wikipedia:Guano] synonym: "ordure" RELATED [] synonym: "piece of shit" EXACT [PMID:23285307] synonym: "portion of dung" NARROW [] synonym: "portion of excrement" EXACT [] synonym: "portion of faeces" EXACT [] synonym: "portion of fecal material" EXACT [] synonym: "portion of fecal matter" EXACT [] synonym: "portion of feces" EXACT [] synonym: "portion of guano" NARROW [] synonym: "portion of scat" NARROW [] synonym: "portionem cacas" EXACT LATIN [] synonym: "scat" NARROW [] synonym: "spoor" RELATED [] synonym: "spraint" NARROW [Wikipedia:Spraint] synonym: "stool" EXACT [] xref: BTO:0000440 xref: CALOHA:TS-2345 xref: ENVO:00002003 xref: FMA:64183 xref: GAID:1199 xref: galen:Feces xref: MA:0002509 xref: MAT:0000053 xref: MESH:D005243 xref: MIAA:0000053 xref: NCIT:C13234 xref: UMLS:C0015733 {source="ncithesaurus:Feces"} xref: Wikipedia:Feces is_a: UBERON:0000174 ! excreta intersection_of: UBERON:0000174 ! excreta intersection_of: output_of GO:0030421 ! defecation relationship: output_of GO:0030421 ! defecation property_value: UBPROP:0000001 "Excretion in semisolid state processed by the intestine.[FMA]" xsd:string {source="FMA:64183"} property_value: UBPROP:0000007 "fecal" xsd:string [Term] id: UBERON:0001994 name: hyaline cartilage tissue namespace: uberon def: "Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000094] subset: pheno_slim subset: uberon_slim synonym: "chondroid cartilage" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "hyaline cartilage" EXACT [MA:0000109] xref: EMAPA:35414 xref: FMA:64783 xref: MA:0000109 xref: NCIT:C32746 xref: SCTID:39298000 xref: UMLS:C0225362 {source="ncithesaurus:Hyaline_Cartilage"} xref: VSAO:0000094 xref: Wikipedia:Hyaline_cartilage xref: XAO:0004029 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002418 {source="FMA"} ! cartilage tissue relationship: composed_primarily_of GO:0005585 {source="VSAO-text-def"} ! collagen type II trimer property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2a/Gray292.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI property_value: UBPROP:0000001 "Cartilage (tissue) which consists of chondrocytes and collagen, the intercellular matrix of which is an amorphous gel with a perichondrium[FMA:64783]." xsd:string {source="FMA:64783"} property_value: UBPROP:0000001 "Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000094", ontology="VSAO", source="PSPUB:0000170"} [Term] id: UBERON:0001996 name: elastic cartilage tissue namespace: uberon def: "Cartilage tissue that is flexible and contains abundant elastic fibers." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000091] subset: pheno_slim subset: uberon_slim synonym: "elastic cartilage" EXACT [MA:0000107] synonym: "elastic cartilage tissue" EXACT [VSAO:0000091] synonym: "reticular cartilage" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "yellow cartilage" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "yellow elastic cartilage" EXACT [Wikipedia:Elastic_cartilage] synonym: "yellow elastic cartilage tissue" EXACT [] xref: FMA:64785 xref: MA:0000107 xref: MA:0000485 xref: NCIT:C32494 xref: UMLS:C0682559 {source="ncithesaurus:Elastic_Cartilage"} xref: VSAO:0000091 xref: Wikipedia:Elastic_cartilage xref: XAO:0004197 is_a: UBERON:0011589 {source="VSAO"} ! non-mineralized cartilage tissue relationship: develops_from UBERON:0005863 {source="VSAO"} ! cartilaginous condensation relationship: has_part GO:0071953 {source="Wikipedia"} ! elastic fiber relationship: has_quality PATO:0001544 ! flexible property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/ca/Gray904.png" xsd:anyURI property_value: UBPROP:0000001 "Cartilage (tissue) which consists of chondrocytes and collagen, the intercellular matrix of which consists of elastic fibers[FMA:64785]." xsd:string {source="FMA:64785"} property_value: UBPROP:0000001 "Cartilage tissue that is flexible and contains abundant elastic fibers.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000091", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000012 "MA has a distinct class for yellow" xsd:string {external_ontology="MA"} [Term] id: UBERON:0002001 name: joint of rib namespace: uberon def: "Any joint that connects a rib to another structure (or another rib). Examples: costochondral, costovertebral, interchondral, sternocostal joints." [https://orcid.org/0000-0002-6601-2165] synonym: "rib joint" EXACT [] xref: FMA_RETIRED:64994 xref: MA:0001508 xref: NCIT:C49575 xref: SCTID:263314001 xref: UMLS:C1261194 {source="ncithesaurus:Joint_of_the_Rib"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002228 ! rib relationship: connects UBERON:0002228 ! rib relationship: part_of UBERON:0014478 {source="cjm"} ! rib skeletal system [Term] id: UBERON:0002008 name: cardiac nerve plexus namespace: uberon def: "A plexus of nerves situated at the base of the heart that innervate the heart." [Wikipedia:Cardiac_plexus] subset: uberon_slim synonym: "autonomic nerve plexus of heart" EXACT [OBOL:automatic] synonym: "autonomic plexus of heart" EXACT [OBOL:automatic] synonym: "cardiac plexus" EXACT [] synonym: "heart autonomic nerve plexus" EXACT [OBOL:automatic] synonym: "heart autonomic plexus" EXACT [OBOL:automatic] synonym: "plexus cardiacus" EXACT LATIN [Wikipedia:Cardiac_plexus] xref: EMAPA:37460 {source="MA:th"} xref: FMA:6628 xref: MA:0001138 xref: NCIT:C52833 xref: SCTID:280511002 xref: UMLS:C0459528 {source="ncithesaurus:Cardiac_Nerve_Plexus"} xref: Wikipedia:Cardiac_plexus is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001816 ! autonomic nerve plexus intersection_of: UBERON:0001816 ! autonomic nerve plexus intersection_of: innervates UBERON:0000948 ! heart relationship: innervates UBERON:0000948 ! heart property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray838.png" xsd:anyURI [Term] id: UBERON:0002011 name: thoracodorsal artery namespace: uberon def: "The thoracodorsal artery is a branch of the subscapular artery. It travels inferiorly with the thoracodorsal nerve and supplies the latissimus dorsi. [WP,unvetted]." [Wikipedia:Thoracodorsal_artery] subset: human_reference_atlas subset: uberon_slim synonym: "arteria thoracodorsalis" RELATED LATIN [Wikipedia:Thoracodorsal_artery] xref: EMAPA:37129 {source="MA:th"} xref: FMA:66320 xref: MA:0002065 xref: NCIT:C53018 xref: UMLS:C0933449 {source="ncithesaurus:Thoracodorsal_Artery"} xref: Wikipedia:Thoracodorsal_artery is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001112 ! latissimus dorsi muscle relationship: connected_to UBERON:0001397 ! subscapular artery relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0001112 ! latissimus dorsi muscle property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/7d/Latissimus_dorsi.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002012 name: pulmonary artery namespace: uberon def: "An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Pulmonary_artery] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "arteria pulmonalis" RELATED LATIN [Wikipedia:Pulmonary_artery] synonym: "pulmonary arterial subtree" RELATED [FMA:66326] synonym: "pulmonary arterial tree" EXACT [FMA:66326] synonym: "pulmonary arterial tree organ part" EXACT [FMA:66326] synonym: "truncus pulmonalis" RELATED LATIN [Wikipedia:Pulmonary_artery] xref: AAO:0010221 xref: BTO:0000778 xref: CALOHA:TS-0839 xref: EFO:0001399 xref: EHDAA2:0001575 xref: EHDAA:4351 xref: EMAPA:17008 xref: FMA:66326 xref: GAID:505 xref: galen:PulmonaryArtery xref: MA:0002031 xref: MESH:D011651 xref: NCIT:C12774 xref: SCTID:181380003 xref: UMLS:C0034052 {source="ncithesaurus:Pulmonary_Artery"} xref: VHOG:0000982 xref: Wikipedia:Pulmonary_artery xref: XAO:0004162 is_a: UBERON:0001637 ! artery is_a: UBERON:0013768 ! great vessel of heart intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0008886 ! pulmonary vascular system intersection_of: supplies UBERON:0002048 ! lung disjoint_from: UBERON:0004573 ! systemic artery relationship: continuous_with UBERON:0002333 ! pulmonary trunk relationship: develops_from UBERON:0002061 {source="Wikipedia"} ! truncus arteriosus relationship: develops_from UBERON:0003123 {source="EHDAA2", source="XAO"} ! pharyngeal arch artery 6 relationship: develops_from UBERON:0005339 {source="EHDAA2"} ! outflow tract pulmonary component relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0008886 ! pulmonary vascular system relationship: supplies UBERON:0002048 ! lung property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Major artery which supplies blood to the lungs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010221", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "One of two arteries, leaving from the heart, the left one supplying the left lung and the right one supplying the right lung. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000982", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pulmonary+artery"} property_value: UBPROP:0000003 "On the other hand, in the sister clade of the actinopterygians, the sarcopterygians, the gill circulation is supplemented with lung ventilation. As a result, the pulmonary artery and vein and a functional ductus arteriosus arose as a major evolutionary innovation from the sixth arch, giving the organism a flexible shunt to balance blood supply to and from gills and lungs according to environmental conditions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000982", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In the human heart, the pulmonary trunk (pulmonary artery or main pulmonary artery) begins at the base of the right ventricle. It is short and wide - approximately 5 cm (2 inches) in length and 3 cm (1.2 inches) in diameter. It then branches into two pulmonary arteries (left and right), which deliver deoxygenated blood to the corresponding lung[WP]" xsd:string [Term] id: UBERON:0002015 name: kidney capsule namespace: uberon def: "The tough fibrous layer surrounding the kidney which is covered in a thick layer of perirenal adipose tissue that functions to provide some protection from trauma and damage." [MGI:anna, MP:0011383] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "capsula fibrosa renis" EXACT LATIN [FMA:66610, FMA:TA] synonym: "capsule of kidney" EXACT [] synonym: "fibrous capsule of kidney" EXACT [FMA:66610] synonym: "renal capsule" EXACT [GO:0072127] xref: EMAPA:18679 xref: FMA:66610 xref: galen:CapsuleOfKidney xref: MA:0000370 xref: NCIT:C12885 xref: SCTID:243657006 xref: UMLS:C0227637 {source="ncithesaurus:Renal_Capsule"} xref: Wikipedia:Kidney_capsule is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003567 ! abdomen connective tissue is_a: UBERON:0011824 ! fibrous connective tissue intersection_of: UBERON:0011824 ! fibrous connective tissue intersection_of: bounding_layer_of UBERON:0002113 ! kidney relationship: bounding_layer_of UBERON:0002113 ! kidney relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/69/Illu_kidney.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000009 "provides some protection from trauma and damage." xsd:string property_value: UBPROP:0000010 "The renal capsule relates to the other layers in the following order (moving from innermost to outermost): renal medulla renal cortex renal capsule perinephric fat (or 'perirenal fat') renal fascia paranephric fat (or 'pararenal fat') peritoneum (anteriorly), and transversalis fascia (posteriorly).[Wikipedia:Kidney_capsule]" xsd:string [Term] id: UBERON:0002016 name: pulmonary vein namespace: uberon def: "Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]." [GO:0060577] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "pulmonary venous tree organ part" EXACT [] synonym: "venae pulmonales" RELATED LATIN [Wikipedia:Pulmonary_vein] xref: AAO:0010521 xref: BTO:0001799 xref: CALOHA:TS-0840 xref: EHDAA2:0001579 xref: EHDAA:2629 xref: EMAPA:18645 xref: FMA:66643 xref: GAID:543 xref: galen:PulmonaryVein xref: MA:0002206 xref: MESH:D011667 xref: NCIT:C12776 xref: SCTID:430160002 xref: UMLS:C0034090 {source="ncithesaurus:Pulmonary_Vein"} xref: VHOG:0001133 xref: Wikipedia:Pulmonary_vein xref: XAO:0000394 is_a: UBERON:0001638 ! vein is_a: UBERON:0013768 ! great vessel of heart intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002048 ! lung relationship: connected_to UBERON:0002079 ! left cardiac atrium relationship: develops_from UBERON:0002061 ! truncus arteriosus relationship: drains UBERON:0002048 ! lung relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0008886 ! pulmonary vascular system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Any of the veins which collect blood from the lungs and some small vesicles received from the esophagus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010521", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "One of two pairs of large vessels that return oxygenated blood from each lung to the left atrium of the heart. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001133", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pulmonary+vein"} property_value: UBPROP:0000001 "the veins that return oxygenated blood from the lungs to the left atrium of the heart" xsd:string {source="MP:0002726,MGI:cwg"} property_value: UBPROP:0000003 "On the other hand, in the sister clade of the actinopterygians, the sarcopterygians, the gill circulation is supplemented with lung ventilation. As a result, the pulmonary artery and vein and a functional ductus arteriosus arose as a major evolutionary innovation from the sixth arch, giving the organism a flexible shunt to balance blood supply to and from gills and lungs according to environmental conditions.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001133", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} property_value: UBPROP:0000202 FMA:70827 [Term] id: UBERON:0002017 name: portal vein namespace: uberon def: "A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]." [BTO:0001792] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "portal venous tree organ part" EXACT [FMA:66645] xref: BTO:0001792 xref: CALOHA:TS-0814 xref: EHDAA2:0001485 xref: EHDAA:6510 xref: EMAPA:17349 xref: FMA:66645 xref: GAID:540 xref: galen:PortalVein xref: MA:0002198 xref: MESH:D011169 xref: NCIT:C33343 xref: SCTID:362064007 xref: UMLS:C0032718 {source="ncithesaurus:Portal_Vein"} xref: VHOG:0000656 xref: XAO:0000392 is_a: UBERON:0001638 {source="FMA"} ! vein relationship: part_of UBERON:0005806 ! portal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/33/Gray591.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002019 name: accessory XI nerve namespace: uberon def: "A cranial nerve that originates from neurons in the medulla and in the cervical spinal cord." [BIRNLEX:812, http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "accessory nerve" EXACT [] synonym: "accessory nerve [XI]" EXACT [] synonym: "accessory spinal nerve" RELATED [BAMS:XIn] synonym: "accessory XI" EXACT [EHDAA2:0000106] synonym: "accessory XI nerve" EXACT [] synonym: "cervical accessory nerve" EXACT [] synonym: "CN-XI" RELATED [VHOG:0000699] synonym: "cranial nerve XI" EXACT [BIRNLEX:812] synonym: "eleventh cranial nerve" EXACT [BIRNLEX:812] synonym: "nervus accessorius [XI]" EXACT LATIN [FMA:6720, FMA:TA] synonym: "pars spinalis nervus accessorius" EXACT LATIN [FMA:6720, FMA:TA] synonym: "radix spinalis nervus accessorius" EXACT LATIN [FMA:6720, FMA:TA] synonym: "spinal accessory nerve" EXACT [FMA:6720] synonym: "spinal accessory nerve tree" EXACT [] synonym: "spinal part of accessory nerve" EXACT [] synonym: "Willis' nerve" EXACT [] xref: AAO:0010476 xref: BAMS:11n xref: BAMS:XIn xref: BIRNLEX:812 xref: EHDAA2:0000106 xref: EHDAA:2855 xref: EMAPA:17265 xref: FMA:6720 xref: FMA:80284 xref: GAID:825 xref: HBA:9340 xref: MA:0001088 xref: MBA:717 xref: MESH:D000055 xref: NCIT:C32041 xref: neuronames:2085 xref: SCTID:362469008 xref: UMLS:C0000905 {source="ncithesaurus:Accessory_Nerve", source="BIRNLEX:812"} xref: UMLS:C1305777 {source="BIRNLEX:812"} xref: VHOG:0000699 xref: Wikipedia:Spinal_accessory_nerve xref: XAO:0004214 is_a: UBERON:0035642 ! laryngeal nerve intersection_of: UBERON:0001021 ! nerve intersection_of: extends_fibers_into UBERON:0020358 ! accessory XI nerve nucleus relationship: extends_fibers_into UBERON:0020358 ! accessory XI nerve nucleus relationship: innervates UBERON:3010692 {gci_relation="part_of", gci_filler="NCBITaxon:8292", source="ISBN:080184780X"} ! m. cucullaris relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5e/Gray791.png" xsd:anyURI property_value: RO:0002174 NCBITaxon:8292 {seeAlso="http://code.google.com/p/xenopus-anatomy-ontology/issues/detail?id=7", source="VHOG", source="Wikipedia"} property_value: UBPROP:0000001 "A small motor nerve which emerges from the lateral wall of the medulla with the roots of the vagus nerve, and innervates a single pectoral suspensory muscle, the m.cucullaris." xsd:string {source="ISBN:080184780X", source="XAO:0004214"} property_value: UBPROP:0000001 "Cranial nerve that innervates the sternocleidomastoid and trapezius complex of muscles. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-1, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000699", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Small motor nerve which innervates a single pectoral suspensory muscle, the m. cucullaris.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010476", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "Cranial nerves XI and XII evolved in the common ancestor to amniotes (non-amphibian tetrapods) thus totalling twelve pairs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000699", ontology="VHOG", source="Wikipedia:Cranial_nerves", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve" xsd:string {source="GO"} property_value: UBPROP:0000012 "FMA has distinct cranial and spinal parts - WP says 'Traditional descriptions of the accessory nerve divide it into two parts: a spinal part and a cranial part.[1] However, because the cranial component rapidly joins the vagus nerve, becoming an integral part of said nerve, modern descriptions often consider the cranial component to be part of the vagus nerve and not part of the accessory nerve proper.[2]" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002020 name: gray matter namespace: uberon def: "A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Gray_matter] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "gray mater" RELATED [ZFA:0001681] synonym: "gray matter" EXACT [] synonym: "gray matter of neuraxis" EXACT [FMA:67242] synonym: "grey matter" EXACT [] synonym: "grey matter of neuraxis" EXACT [] synonym: "grey substance" EXACT [] synonym: "grisea" RELATED LATIN [] synonym: "neuronal grey matter" EXACT [AEO:0001012] synonym: "substantia grisea" EXACT LATIN [FMA:67242, FMA:TA] xref: AEO:0001012 xref: EHDAA2:0003136 xref: EHDAA2_RETIRED:0004658 xref: EMAPA:37596 {source="MA:th"} xref: FMA:67242 xref: HBA:4006 xref: MA:0001112 xref: MESH:D066128 xref: NCIT:C32695 xref: neuronames:2869 xref: TAO:0002197 xref: UMLS:C0018220 {source="ncithesaurus:Gray_Matter"} xref: VHOG:0001768 xref: Wikipedia:Gray_matter xref: ZFA:0001681 is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: composed_primarily_of GO:0043025 ! neuronal cell body property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg" xsd:anyURI property_value: UBPROP:0000001 "Multi-tissue comprised of neurons, dendrites, axon terminals, glial cells, and capillaries.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002197", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0002028 name: hindbrain namespace: uberon def: "The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]." [Wikipedia:Rhombencephalon, ZFA:0000029, ZFIN:curator] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "rhombencephalon" RELATED [] xref: AAO:0010150 xref: BAMS:HB xref: BIRNLEX:942 xref: BTO:0000672 xref: CALOHA:TS-0457 xref: DHBA:10653 xref: DMBA:16808 xref: EFO:0000923 xref: EHDAA2:0000746 xref: EHDAA:3514 xref: EHDAA:6487 xref: EMAPA:16916 xref: FMA:67687 xref: MA:0000195 xref: MAT:0000107 xref: MBA:1065 xref: MESH:D012249 xref: MIAA:0000107 xref: NCIT:C40336 xref: neuronames:540 {source="BIRNLEX:942"} xref: SCTID:303456008 xref: TAO:0000029 xref: UMLS:C0035507 {source="ncithesaurus:Hind-Brain", source="BIRNLEX:942"} xref: UMLS:C1522180 {source="BIRNLEX:942"} xref: VHOG:0000070 xref: Wikipedia:Rhombencephalon xref: XAO:0000015 xref: ZFA:0000029 is_a: UBERON:0002616 ! regional part of brain relationship: contributes_to_morphology_of UBERON:0000955 ! brain relationship: develops_from UBERON:0007277 ! presumptive hindbrain relationship: immediate_transformation_of UBERON:0007277 {source="Bgee:AN"} ! presumptive hindbrain relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: overlaps UBERON:0002298 {notes="modified-source-relation", source="ABA"} ! brainstem property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI property_value: RO:0002171 UBERON:0001891 {exceptions="ZFA", source="ABA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"} property_value: RO:0002171 UBERON:0001894 {source="ABA"} property_value: RO:0002175 NCBITaxon:7762 {source="PMID:8932866"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Posterior part of the brain consisting of the cerebellum and medulla oblongata.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010150", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The most posterior of the three principal regions of the brain, forming the rhombencephalon and all or most of the metencephalon. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000029", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from hindbrain neural tube (TAO:0007043)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000029", ontology="TAO"} property_value: UBPROP:0000003 "Fine structural, computerized three-dimensional (3D) mapping of cell connectivity in the amphioxus nervous system and comparative molecular genetic studies of amphioxus and tunicates have provided recent insights into the phylogenetic origin of the vertebrate nervous system. The results suggest that several of the genetic mechanisms for establishing and patterning the vertebrate nervous system already operated in the ancestral chordate and that the nerve cord of the proximate invertebrate ancestor of the vertebrates included a diencephalon, midbrain, hindbrain, and spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000070", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "rhombencephalic" xsd:string property_value: UBPROP:0000012 "in MA, brainstem and hindbrain and part-of siblings under brain, consistent with FMA and NIF. See also notes for cerebellum. We weaken the relation in ABA to overlaps" xsd:string {external_ontology="MA"} [Term] id: UBERON:0002029 name: epithelium of gall bladder namespace: uberon def: "The simple columnar epithelial lining of the gall bladder." [MP:0009492] subset: pheno_slim synonym: "biliary epithelium" RELATED [] synonym: "epithelial tissue of gall bladder" EXACT [OBOL:automatic] synonym: "epithelial tissue of gallbladder" EXACT [OBOL:automatic] synonym: "epithelium of gallbladder" EXACT [OBOL:automatic] synonym: "gall bladder epithelial tissue" EXACT [OBOL:automatic] synonym: "gall bladder epithelium" EXACT [] synonym: "gallbladder epithelial tissue" EXACT [OBOL:automatic] synonym: "gallbladder epithelium" EXACT [OBOL:automatic] xref: BTO:0001449 xref: CALOHA:TS-1304 xref: EMAPA:35370 xref: FMA:67711 xref: MA:0001632 xref: NCIT:C49227 xref: UMLS:C1180206 {source="ncithesaurus:Gallbladder_Epithelium"} is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0034932 ! epithelium of biliary system intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002110 ! gallbladder relationship: contributes_to_morphology_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: UBERON:0002031 name: epithelium of bronchus namespace: uberon def: "An epithelium that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] subset: efo_slim subset: pheno_slim synonym: "bronchi epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchi epithelium" EXACT [OBOL:automatic] synonym: "bronchial epithelium" EXACT [] synonym: "bronchial trunk epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk epithelium" EXACT [OBOL:automatic] synonym: "bronchus epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchus epithelium" EXACT [] synonym: "epithelial tissue of bronchi" EXACT [OBOL:automatic] synonym: "epithelial tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "epithelial tissue of bronchus" EXACT [OBOL:automatic] synonym: "epithelium of bronchi" EXACT [OBOL:automatic] synonym: "epithelium of bronchial trunk" EXACT [OBOL:automatic] xref: BTO:0001845 xref: CALOHA:TS-1240 xref: EFO:0000307 xref: EMAPA:32691 xref: FMA:67782 xref: MA:0001839 xref: NCIT:C32231 xref: UMLS:C0599333 {source="ncithesaurus:Bronchial_Epithelium"} is_a: UBERON:0008397 ! tracheobronchial epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002185 ! bronchus relationship: contributes_to_morphology_of UBERON:0002185 ! bronchus relationship: has_part CL:0002209 {source="FMA"} ! intermediate epitheliocyte relationship: part_of UBERON:0002185 ! bronchus [Term] id: UBERON:0002036 name: striated muscle tissue namespace: uberon def: "Muscle tissue that contains fibers that are divided by transverse bands into striations." [CL:0000737, GOC:dph, GOC:mtg_muscle] subset: pheno_slim subset: uberon_slim synonym: "striated muscle" EXACT [] xref: AAO:0010762 xref: AEO:0000140 xref: CALOHA:TS-2047 xref: EHDAA2:0003140 xref: EMAPA:36390 xref: FMA:67905 xref: galen:StriatedMuscle xref: MA:0002438 xref: NCIT:C12436 xref: UMLS:C1331262 {source="ncithesaurus:Striated_Muscle_Tissue"} xref: WBbt:0005779 xref: Wikipedia:Striated_muscle is_a: UBERON:0002385 ! muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: composed_primarily_of CL:0000737 ! striated muscle cell relationship: composed_primarily_of CL:0000737 ! striated muscle cell property_value: UBPROP:0000001 "Voluntary muscle tissue arranged in bundles of fibers.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010762", ontology="AAO", source="AAO:CAM"} [Term] id: UBERON:0002040 name: bronchial artery namespace: uberon def: "A systemic artery that supplies the lung with with oxygenated blood." [UBERON:cjm, Wikipedia:Bronchial_artery] comment: Although there is much variation, there are usually two bronchial arteries that run to the left lung, and one to the right lung. subset: human_reference_atlas subset: uberon_slim synonym: "arteriae bronchiales" RELATED LATIN [Wikipedia:Bronchial_artery] synonym: "bronchial arterial tree" EXACT [] synonym: "rami bronchiales partis thoracicae aortae" RELATED LATIN [Wikipedia:Bronchial_artery] xref: EMAPA:18608 xref: FMA:68109 xref: GAID:477 xref: MA:0001923 xref: MESH:D001981 xref: NCIT:C32230 xref: SCTID:244247009 xref: UMLS:C0006257 {source="ncithesaurus:Bronchial_Artery"} xref: Wikipedia:Bronchial_artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0004573 ! systemic artery intersection_of: part_of UBERON:0004571 ! systemic arterial system intersection_of: supplies UBERON:0002048 ! lung relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0002048 ! lung property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray1032.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002047 name: pontine raphe nucleus namespace: uberon def: "The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]." [Wikipedia:Pontine_raphe_nucleus] subset: pheno_slim subset: uberon_slim synonym: "nucleus raphe pontis" RELATED LATIN [NeuroNames:589] synonym: "nucleus raphes pontis" RELATED LATIN [Wikipedia:Pontine_raphe_nucleus] synonym: "raphe (mediana pontina)" RELATED LATIN [NeuroNames:589] synonym: "raphe of pons" EXACT [] synonym: "raphe pontis" EXACT LATIN [FMA:68875, FMA:TA] synonym: "raphe pontis nucleus" RELATED [] xref: BAMS:PnR xref: BAMS:RA-PONS xref: BAMS:RPn xref: BIRNLEX:1110 xref: DHBA:12471 xref: DHBA:12475 xref: FMA:68875 xref: HBA:9159 xref: MA:0001022 xref: MBA:238 xref: neuronames:589 {source="BIRNLEX:1110"} xref: UMLS:C0175423 {source="BIRNLEX:1110"} xref: Wikipedia:Pontine_raphe_nucleus is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus relationship: part_of UBERON:0003023 ! pontine tegmentum relationship: part_of UBERON:0004684 {source="Wikipedia"} ! raphe nuclei property_value: RO:0002171 UBERON:0002148 {source="ABA"} property_value: RO:0002171 UBERON:0002267 {source="ABA"} property_value: RO:0002171 UBERON:0002587 {source="ABA"} property_value: RO:0002171 UBERON:0003004 {source="ABA"} [Term] id: UBERON:0002048 name: lung namespace: uberon def: "Respiration organ that develops as an outpocketing of the esophagus." [http://orcid.org/0000-0002-6601-2165] comment: Snakes and limbless lizards typically possess only the right lung as a major respiratory organ; the left lung is greatly reduced, or even absent. Amphisbaenians, however, have the opposite arrangement, with a major left lung, and a reduced or absent right lung [WP] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "pulmo" EXACT LATIN [] xref: AAO:0000275 xref: AAO:0010567 xref: BTO:0000763 xref: CALOHA:TS-0568 xref: EFO:0000934 xref: EHDAA2:0001042 xref: EHDAA:1554 xref: EHDAA:2205 xref: EMAPA:16728 xref: EV:0100042 xref: FMA:7195 xref: GAID:345 xref: galen:Lung xref: MA:0000415 xref: MAT:0000135 xref: MESH:D008168 xref: MIAA:0000135 xref: NCIT:C12468 xref: SCTID:181216001 xref: UMLS:C0024109 {source="ncithesaurus:Lung"} xref: VHOG:0000310 xref: Wikipedia:Lung xref: XAO:0000119 is_a: UBERON:0000171 ! respiration organ is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005178 ! thoracic cavity element is_a: UBERON:0015212 ! lateral structure relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system relationship: develops_from UBERON:0000118 ! lung bud relationship: in_lateral_side_of UBERON:0000170 ! pair of lungs relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of UBERON:0000170 {note="some species only have a single lung"} ! pair of lungs relationship: surrounded_by UBERON:0009778 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! pleural sac property_value: RO:0002161 NCBITaxon:32443 {editor="https://orcid.org/0000-0002-9415-5104", source="https://github.com/obophenotype/uberon/issues/701"} property_value: RO:0002161 NCBITaxon:7777 {editor="https://orcid.org/0000-0002-9415-5104", source="https://github.com/obophenotype/uberon/issues/701"} property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/701" xsd:anyURI property_value: UBPROP:0000001 "Either of two organs which allow gas exchange absorbing oxygen from inhaled air and releasing carbon dioxide with exhaled air.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010567", ontology="AAO", source="AAO:SBH"} property_value: UBPROP:0000003 "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata. (...) In actinopterygian fishes, apart from Cladistia, the ventral intestinal pocket migrates dorsally and becomes the swim-bladder, a mainly hydrostatical organ (reference 1); Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000310", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.210, DOI:10.1371/journal.pone.0024019 Zheng W, Wang Z, Collins JE, Andrews RM, Stemple D, Gong Z, Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung. PLoS One (2011)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "pulmonary" xsd:string property_value: UBPROP:0000008 "respiration organ in all air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located in the chest on either side of the heart. Their principal function is to transport oxygen from the atmosphere into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere. This exchange of gases is accomplished in the mosaic of specialized cells that form millions of tiny, exceptionally thin-walled air sacs called alveoli. // Avian lungs do not have alveoli as mammalian lungs do, they have Faveolar lungs. They contain millions of tiny passages known as para-bronchi, connected at both ends by the dorsobronchi" xsd:string [Term] id: UBERON:0002049 name: vasculature namespace: uberon def: "An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face." [ZFA:0005249] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "vascular network" EXACT [FMA:69050] xref: BTO:0003718 xref: FMA:69050 xref: TAO:0005249 xref: ZFA:0005249 is_a: UBERON:0000477 {source="FMA"} ! anatomical cluster relationship: composed_primarily_of UBERON:0000055 ! vessel relationship: has_part UBERON:0000179 ! haemolymphatic fluid relationship: part_of UBERON:0007798 ! vascular system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Circulatory_System_en.svg" xsd:anyURI property_value: editor_note "see also: vascular system. Consider merging?" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "vascular" xsd:string [Term] id: UBERON:0002050 name: embryonic structure namespace: uberon def: "Anatomical structure that is part of an embryo." [BTO:0000174, ZFIN:curator] subset: efo_slim subset: inconsistent_with_fma subset: vertebrate_core synonym: "developing embryonic structure" EXACT [FBbt:00004208] synonym: "developing structure" RELATED [] synonym: "embryonale Struktur" RELATED [BTO:0000174] synonym: "embryonic anatomical structure" EXACT [RETIRED_EHDAA2:0003169] synonym: "embryonic structures" RELATED PLURAL [ZFA:0001105] xref: AAO:0000138 xref: BILA:0000034 xref: BTO:0000174 xref: CALOHA:TS-2110 xref: EFO:0000461 xref: FBbt:00004208 xref: FMA:69067 xref: GAID:407 xref: MESH:D004628 xref: NCIT:C13229 xref: RETIRED_EHDAA2:0003169 xref: SCTID:667009 xref: TAO:0001105 xref: UMLS:C0013948 {source="ncithesaurus:Embryonic_Structure"} xref: VSAO:0000178 xref: XAO:0003042 xref: ZFA:0001105 is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo property_value: UBPROP:0000001 "Anatomical structure that is part of the embryo and is comprised of portions of tissue or cells.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000138", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Anatomical structure that is part of the embryo and is comprised of portions of tissue or cells.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001105", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Anatomical structure that is part of the embryo and is comprised of portions of tissue or cells.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000178", ontology="VSAO", source="ZFIN:curator"} property_value: UBPROP:0000012 "in FMA embryo is_a embryonic structure" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002051 name: epithelium of bronchiole namespace: uberon def: "An epithelium that is part of a bronchiole [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "bronchiolar epithelium" EXACT [BTO:0001866] synonym: "bronchiole epithelial tissue" EXACT [OBOL:automatic] synonym: "bronchiole epithelium" EXACT [] synonym: "epithelial tissue of bronchiole" EXACT [OBOL:automatic] xref: BTO:0001866 xref: CALOHA:TS-0570 xref: EMAPA:32693 xref: FMA:69077 xref: MA:0001772 xref: NCIT:C48942 xref: UMLS:C1181296 {source="ncithesaurus:Bronchiole_Epithelium"} is_a: UBERON:0000115 ! lung epithelium is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0008397 ! tracheobronchial epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002186 ! bronchiole relationship: contributes_to_morphology_of UBERON:0002186 ! bronchiole relationship: has_part CL:0002145 {source="FMA"} ! ciliated columnar cell of tracheobronchial tree relationship: part_of UBERON:0005039 ! mucosa of bronchiole property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002057 name: phrenic artery namespace: uberon def: "An artery that supplies the diaphragm." [https://orcid.org/0000-0002-6601-2165] subset: uberon_slim xref: EMAPA:37108 {source="MA:th"} xref: FMA:69330 xref: MA:0002019 xref: NCIT:C33320 xref: UMLS:C1181536 {source="ncithesaurus:Phrenic_Artery"} is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0004573 ! systemic artery intersection_of: supplies UBERON:0001103 ! diaphragm relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0001103 ! diaphragm property_value: UBPROP:0000008 "In humans this includes the superior and inferior phrenic arteries" xsd:string [Term] id: UBERON:0002060 name: femoral artery namespace: uberon def: "The femoral artery is a large artery in the muscles of the thigh. It is a continuation of external iliac artery where it enters the femoral triangle at the mid inguinal point behind the inguinal ligament. It leaves femoral triangle through apex beneath the sartorius muscle. It enters the popliteal fossa by passing through the 5th osseo-aponeurotic(adductor hiatus) opening of adductor magnus where it becomes the Popliteal Artery. [WP,unvetted]." [Wikipedia:Femoral_artery] subset: uberon_slim synonym: "arteria femoralis" RELATED LATIN [Wikipedia:Femoral_artery] xref: AAO:0010222 xref: BTO:0001624 xref: CALOHA:TS-0321 xref: EMAPA:35342 xref: FMA:70248 xref: GAID:494 xref: galen:FemoralArtery xref: MA:0001951 xref: MESH:D005263 xref: NCIT:C12715 xref: SCTID:244332003 xref: UMLS:C0015801 {source="ncithesaurus:Femoral_Artery"} xref: Wikipedia:Femoral_artery is_a: UBERON:0004573 ! systemic artery relationship: branching_part_of UBERON:0001308 {source="FMA", source="WP"} ! external iliac artery relationship: part_of UBERON:0001308 ! external iliac artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7d/Gray546.png" xsd:anyURI property_value: UBPROP:0000001 "Artery which supplies blood via branches to the hindlimbs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010222", ontology="AAO", source="AAO:BJB"} [Term] id: UBERON:0002061 name: truncus arteriosus namespace: uberon def: "The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles." [Wikipedia:Truncus_arteriosus_(embryology)] subset: uberon_slim xref: EHDAA2:0004143 xref: EMAPA:35887 xref: FMA:70301 xref: GAID:554 xref: MA:0000103 xref: MESH:D014338 xref: NCIT:C34317 xref: SCTID:308828009 xref: UMLS:C1519589 {source="ncithesaurus:Trancus_Arteriosus"} xref: Wikipedia:Truncus_arteriosus_(embryology) is_a: UBERON:0001637 {source="EHDAA2"} ! artery is_a: UBERON:0002050 {source="FMA"} ! embryonic structure is_a: UBERON:0003498 ! heart blood vessel relationship: develops_from UBERON:0005432 {source="EHDAA2"} ! aortic sac relationship: part_of UBERON:0004145 {source="MA"} ! outflow tract relationship: part_of UBERON:0005498 {source="EHDAA2"} ! primitive heart tube property_value: UBPROP:0000012 "assume spelling error for ncit" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0002062 name: endocardial cushion namespace: uberon def: "The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]." [GO:0003197, Wikipedia:Atrioventricular_cushions, ZFIN:curator] comment: GO graph seems to suggest this is an endothelium. WP: The endocardial cushions are thought to arise from a subset of endothelial cells that undergo epithelial to mesenchymal transformation, a process whereby these cells break cell-to-cell contacts and migrate into the cardiac jelly (towards to interior of the heart tube). Latest (2010-06-01) new def suggested for GO, added above. Note that EHDAA2 has a more detailed model which we may later adopt. JB: Patterning makes the cushions lay down connective tissue in three domains that force out the local endothelial lining and so the leaflets form subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "atrioventricular canal cushion" RELATED [FMA:70302] synonym: "atrioventricular cushion" EXACT [Wikipedia:Endocardial_cushion] synonym: "AV cushion" EXACT [] synonym: "cardiac cushion" EXACT [PMID:15797462] synonym: "endocardial cushion tissue" EXACT [EHDAA2:0000434] synonym: "endocardial cushions" RELATED PLURAL [] xref: EHDAA2:0000434 xref: EHDAA2:0004028 xref: EHDAA:2586 xref: EMAPA:16696 xref: FMA:70302 xref: MA:0000078 xref: MESH:D054089 xref: TAO:0001317 xref: VHOG:0000932 xref: Wikipedia:Atrioventricular_cushions xref: XAO:0004189 xref: ZFA:0001317 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0005256 ! trunk mesenchyme is_a: UBERON:0009751 ! cardiac mesenchyme is_a: UBERON:0014387 ! mesenchyme derived from neural crest relationship: part_of UBERON:0002165 {source="ZFA"} ! endocardium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png" xsd:anyURI property_value: UBPROP:0000001 "Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001317", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from endocardial ring (TAO:0005072)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001317", ontology="TAO"} property_value: UBPROP:0000003 "(Cardiac valve formation in vertebrates) In response to a myocardial signal, endocardial cells at chamber boundaries take on a mesenchymal character, delaminate and migrate into the cardiac jelly. There, they form an endocardial cushion that is later remodelled into a valve.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000932", ontology="VHOG", source="DOI:10.1038/35047564 Stainier DYR, Zebrafish genetics and vertebrate heart formation. Nature Reviews Genetics (2001) Figure 3", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002063 name: sinus venosus namespace: uberon def: "The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart." [PMID:20735616, Wikipedia:Sinus_venosus] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "inflow tract" BROAD [ZFA:0000154] synonym: "sinus venarum" RELATED [Wikipedia:Sinus_venosus] synonym: "sinus venosus cordis" RELATED LATIN [Wikipedia:Sinus_venosus] synonym: "venarum" RELATED [Wikipedia:Sinus_venosus] synonym: "venarum sinus" RELATED [Wikipedia:Sinus_venosus] synonym: "venosus" RELATED [Wikipedia:Sinus_venosus] xref: AAO:0010505 xref: EHDAA2:0001839 xref: EHDAA:480 xref: EMAPA:16237 xref: FMA:70303 xref: NCIT:C34299 xref: NCIT:C34300 xref: TAO:0000154 xref: UMLS:C0225857 {source="ncithesaurus:Sinus_Venarum"} xref: UMLS:C0231084 {source="ncithesaurus:Sinus_Venosus"} xref: VHOG:0000177 xref: Wikipedia:Sinus_venosus xref: ZFA:0000154 is_a: UBERON:0004151 ! cardiac chamber relationship: develops_from UBERON:0007278 ! presumptive sinus venosus relationship: immediate_transformation_of UBERON:0007278 {source="Bgee:AN"} ! presumptive sinus venosus relationship: part_of UBERON:0002350 {source="VHOG"} ! conducting system of heart property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c7/Gray465.png" xsd:anyURI property_value: UBPROP:0000001 "Heart region collecting blood from the paired common cardinal veins and delivering to the atrium. One of four components of the heart. The sinus venosus also acts as a pacemaker and is the first to contract. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000154", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of the circulatory system which receives blood from the systemic veins and contracts to pump the blood into the atrium of the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010505", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "In the primitive vertebrate heart the four chambers are: 1. Sinus venosus (...) 2. Atrium (...) 3. Ventricle (...) 4. Conus arteriosus (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000177", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.428", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In fish, receives venous blood from the systemic circulation through paired hepatic veins, anterior jugular veins and Cuvierian ducts[PMID:20735616]" xsd:string property_value: UBPROP:0000008 "In humans, it exists distinctly only in the embryonic heart, where it is found between the two venae cavae. In the adult, it is incorporated into the wall of the right atrium to form a smooth part called the sinus venarum, also known as the venarum sinus, which is separated from the rest of the atrium by a ridge of fibres called the crista terminalis. The sinus venosus also forms the SA node and the coronary sinus. In the embryo, the thin walls of the sinus venosus are connected below with the right ventricle, and medially with the left atrium, but are free in the rest of their extent. It receives blood from the vitelline vein, umbilical vein and common cardinal vein. It originally starts as a paired structure but shifts towards associating only with the right atrium as the embryonic heart develops. The left portion shrinks in size and eventually forms the coronary sinus and oblique vein of the left atrium, whereas the right part becomes incorporated into the right atrium to form the sinus venarmu" xsd:string property_value: UBPROP:0000008 "In zebrafish, the sinus venosus also acts as a pacemaker and is the first to contract" xsd:string {source="ZFA:0000154"} [Term] id: UBERON:0002067 name: dermis namespace: uberon def: "The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]." [Wikipedia:Dermis, ZFIN:curator] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "corium" RELATED LATIN [BTO:0000294, Wikipedia:Dermis] synonym: "cutis" RELATED [BTO:0000294] synonym: "vertebrate dermis" EXACT [] xref: AAO:0000128 xref: BTO:0000294 xref: CALOHA:TS-2076 xref: EFO:0000953 xref: EMAPA:17527 xref: EV:0100154 xref: FMA:70323 xref: GAID:1321 xref: MA:0000152 xref: MAT:0000153 xref: MESH:D020405 xref: MIAA:0000153 xref: NCIT:C12701 xref: SCTID:361696001 xref: TAO:0001119 xref: UMLS:C0011646 {source="ncithesaurus:Dermis"} xref: VHOG:0000108 xref: Wikipedia:Dermis xref: XAO:0000217 xref: ZFA:0001119 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0013754 ! integumentary system layer relationship: composed_primarily_of UBERON:0002384 ! connective tissue relationship: deep_to UBERON:0001003 ! skin epidermis relationship: develops_from UBERON:0010083 ! future dermis relationship: has_part GO:0071953 ! elastic fiber relationship: has_part UBERON:0011860 ! collection of collagen fibrils relationship: immediate_transformation_of UBERON:0010083 {evidence="definitional"} ! future dermis relationship: part_of UBERON:0002097 {source="FMA"} ! skin of body relationship: superficial_to UBERON:0002072 ! hypodermis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/23/EpidermisPainted.svg" xsd:anyURI property_value: editor_note "Consider adding a layer-of-skin grouping class for all skin layers" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A collagenous layer of the skin subjacent to the epidermis and covering the hypodermis. It contains various types of cells (e.g. fibroblasts, pigment cells, nerve, blood vessels and scales. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001119", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "When approaching controversies surrounding skin evolution, we need to remember that the skin consists of two layers, an epidermis and a dermis, not a single evolving structure. (...) It is little wonder that controversies about homology exist. If we think of the epidermis, the dermis, and their interactions as an evolving unit, then their specialized products (hair, feathers, and reptilian scales) are broadly homologous.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000108", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.231-232 see also p.209 and p.228 and Figure 6-1", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "dermal" xsd:string [Term] id: UBERON:0002072 name: hypodermis namespace: uberon def: "Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]." [Wikipedia:Hypodermis] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "hypoderm" EXACT [] synonym: "sub-tegumental tissue" RELATED [BTO:0004525] synonym: "subcutaneous tissue" RELATED [Wikipedia:Hypodermis] synonym: "subcutis" RELATED [] synonym: "subtegumental tissue" RELATED [BTO:0004525] synonym: "superficial fascia" RELATED INCONSISTENT [] synonym: "tela subcutanea" RELATED LATIN [Wikipedia:Hypodermis] synonym: "vertebrate hypodermis" EXACT [] xref: BTO:0001314 xref: CALOHA:TS-2366 xref: EMAPA:37505 {source="MA:th"} xref: FMA:70544 xref: NCIT:C33645 xref: TAO:0001136 xref: UMLS:C0278403 {source="ncithesaurus:Subcutis"} xref: Wikipedia:Hypodermis xref: ZFA:0001136 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0013754 ! integumentary system layer relationship: composed_primarily_of UBERON:0001013 ! adipose tissue relationship: composed_primarily_of UBERON:0011825 {source="FMA-modified"} ! loose connective tissue relationship: deep_to UBERON:0002067 ! dermis relationship: part_of UBERON:0002199 {source="ZFA"} ! integument relationship: superficial_to UBERON:0001015 ! musculature property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001136", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA:70544]." xsd:string {source="FMA:70544"} property_value: UBPROP:0000007 "hypodermal" xsd:string property_value: UBPROP:0000007 "subcutaneous" xsd:string property_value: UBPROP:0000007 "subcutaneus" xsd:string property_value: UBPROP:0000012 "BTO has 'subcutis', as part of dermis. We follow FMA in having distinct classes for hypodermis and superficial fascia, and including these as part of the non-skin intgeument." xsd:string {external_ontology="BTO"} [Term] id: UBERON:0002075 name: viscus namespace: uberon def: "An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen." [BTO:0001491, https://github.com/obophenotype/mouse-anatomy-ontology/issues/14, Wikipedia:Viscus] subset: organ_slim subset: pheno_slim subset: uberon_slim subset: upper_level synonym: "splanchnic tissue" RELATED [BTO:0001491] synonym: "viscera" RELATED [] synonym: "visceral organ" EXACT [RETIRED_EHDAA2:0002201] synonym: "visceral organ system" EXACT [MA:0000019] synonym: "visceral tissue" RELATED [BTO:0001491] xref: AAO:0010386 xref: BTO:0001491 xref: EHDAA:512 xref: EMAPA:16245 xref: FMA:7085 xref: MA:0000019 xref: MESH:D014781 xref: NCIT:C28287 xref: RETIRED_EHDAA2:0002201 xref: SCTID:118760003 xref: UMLS:C0042779 {source="ncithesaurus:Viscera"} xref: Wikipedia:Viscus xref: XAO:0003034 is_a: UBERON:0005177 ! trunk region element intersection_of: UBERON:0000062 ! organ intersection_of: located_in UBERON:0002323 ! coelemic cavity lumen relationship: located_in UBERON:0002323 ! coelemic cavity lumen property_value: UBPROP:0000001 "An internal organ of the body; especially: one (as the heart, liver, or intestine) located in the great cavity of the trunk proper.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010386", ontology="AAO", source="BTO:0001491"} property_value: UBPROP:0000012 "general anatomical term in FMA. Note that we place the MA class here temporarily, although properly systems should be distinguished from organs." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002078 name: right cardiac atrium namespace: uberon def: "A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Right_atrium] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "atrium dextrum" RELATED LATIN [Wikipedia:Right_atrium] synonym: "cardiac right atrium" EXACT [] synonym: "heart right atrium" EXACT [MA:0000075] synonym: "right atrium" EXACT [VHOG:0000328] synonym: "right atrium of heart" EXACT [] synonym: "right cardiac atrium" EXACT [] xref: AAO:0010248 xref: BTO:0001703 xref: EHDAA2:0000290 xref: EMAPA:17321 xref: FMA:7096 xref: galen:RightAtrium xref: MA:0000075 xref: NCIT:C12868 xref: SCTID:244383003 xref: UMLS:C0225844 {source="ncithesaurus:Right_Atrium"} xref: VHOG:0000328 xref: Wikipedia:Right_atrium xref: XAO:0003192 is_a: UBERON:0002081 ! cardiac atrium is_a: UBERON:0035554 ! right cardiac chamber intersection_of: UBERON:0002081 ! cardiac atrium intersection_of: in_right_side_of UBERON:0000948 ! heart relationship: connected_to UBERON:0004537 ! blood vasculature relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Right cardiac chamber which is continuous with the superior vena cava and inferior vena cava.[FMA]" xsd:string {source="FMA:7096"} property_value: UBPROP:0000003 "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000328", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0002079 name: left cardiac atrium namespace: uberon def: "A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Left_atrium] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "atrium sinistrum" EXACT LATIN [Wikipedia:Left_atrium] synonym: "cardiac left atrium" EXACT [] synonym: "heart left atrium" EXACT [MA:0000074] synonym: "left atrium" EXACT [VHOG:0000369] synonym: "left atrium of heart" EXACT [] synonym: "left cardiac atrium" EXACT [] xref: AAO:0010247 xref: BTO:0001702 xref: EHDAA2:0000275 xref: EMAPA:17315 xref: FMA:7097 xref: galen:LeftAtrium xref: MA:0000074 xref: NCIT:C12869 xref: SCTID:244387002 xref: UMLS:C0225860 {source="ncithesaurus:Left_Atrium"} xref: VHOG:0000369 xref: Wikipedia:Left_atrium xref: XAO:0003191 is_a: UBERON:0002081 ! cardiac atrium is_a: UBERON:0035553 ! left cardiac chamber intersection_of: UBERON:0002081 ! cardiac atrium intersection_of: in_left_side_of UBERON:0000948 ! heart relationship: connected_to UBERON:0004537 ! blood vasculature relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Left cardiac chamber which is continuous with the pulmonary venous trunk.[FMA]" xsd:string {source="FMA:7097"} property_value: UBPROP:0000001 "The chamber of the heart that receives blood from the lungs[XAO:EJS]." xsd:string {source="XAO:EJS"} property_value: UBPROP:0000003 "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000369", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0002080 name: heart right ventricle namespace: uberon def: "A cardiac ventricle that is in the right side of the heart." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "cardiac right ventricle" EXACT [] synonym: "right cardiac ventricle" RELATED [EMAPA:17340] synonym: "right ventricle" EXACT [FMA:7098] synonym: "right ventricle of heart" EXACT [] synonym: "ventriculus dexter" RELATED LATIN [Wikipedia:Right_ventricle] xref: BTO:0001630 xref: CALOHA:TS-0443 xref: EHDAA2:0000196 xref: EMAPA:17340 xref: FMA:7098 xref: galen:RightVentricle xref: MA:0000093 xref: NCIT:C12870 xref: SCTID:244384009 xref: UMLS:C0225883 {source="ncithesaurus:Right_Ventricle"} xref: VHOG:0000717 xref: Wikipedia:Right_ventricle is_a: UBERON:0002082 ! cardiac ventricle is_a: UBERON:0035554 ! right cardiac chamber intersection_of: UBERON:0002082 ! cardiac ventricle intersection_of: in_right_side_of UBERON:0000948 ! heart relationship: connected_to UBERON:0004537 ! blood vasculature relationship: develops_from UBERON:0009889 {source="PMID:17276708"} ! secondary heart field relationship: has_developmental_contribution_from UBERON:0004706 {source="cjm"} ! bulbus cordis relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The muscular chamber on the right and in front of the left ventricle. It generally receives venous blood from the right atrium and conveys it into the pulmonary artery. [(1988)_Dorian_AF, Amsterdam, Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B._Anatomy, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier's_Encyclopaedic_Dictionary_of_Medicine][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000717", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI property_value: UBPROP:0000008 "In mammals continuous with the pulmonary arteries" xsd:string [Term] id: UBERON:0002081 name: cardiac atrium namespace: uberon def: "Cardiac chamber in which blood enters the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heart_atrium] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "atria" EXACT PLURAL [] synonym: "atrial tissue" RELATED [BTO:0000903] synonym: "atrium" EXACT [ZFA:0000471] synonym: "atrium of heart" EXACT [] synonym: "cardiac atria" EXACT PLURAL [] synonym: "heart atrium" EXACT [] xref: AAO:0010246 xref: BTO:0000903 xref: CALOHA:TS-0437 xref: EFO:0000277 xref: EHDAA2:0000154 xref: EHDAA:1265 xref: EMAPA:16688 xref: EV:0100019 xref: FMA:7099 xref: GAID:555 xref: galen:Atrium xref: MA:0000073 xref: MAT:0000496 xref: MESH:D006325 xref: NCIT:C12728 xref: SCTID:261405004 xref: TAO:0000471 xref: UMLS:C0018792 {source="ncithesaurus:Cardiac_Atrium"} xref: VHOG:0000175 xref: Wikipedia:Heart_atrium xref: ZFA:0000471 is_a: UBERON:0004151 ! cardiac chamber relationship: contributes_to_morphology_of UBERON:0000948 ! heart relationship: develops_from UBERON:0010227 ! future cardiac atrium relationship: immediate_transformation_of UBERON:0010227 ! future cardiac atrium property_value: UBPROP:0000001 "One of four heart chambers.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000471", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "One of two chambers of the heart which receive blood from the veins and forces it by muscular contration to the ventricle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010246", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "In the primitive vertebrate heart the four chambers are: 1. Sinus venosus (...) 2. Atrium (...) 3. Ventricle (...) 4. Conus arteriosus (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000175", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.428", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002082 name: cardiac ventricle namespace: uberon def: "Cardiac chamber through which blood leaves the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Ventricle_(heart)] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "heart ventricle" EXACT [] synonym: "lower chamber of heart" EXACT [] synonym: "ventricle" BROAD [] synonym: "ventricle of heart" EXACT [] xref: AAO:0010249 xref: BTO:0000862 xref: CALOHA:TS-0444 xref: EFO:0000317 xref: EHDAA2:0004164 xref: EHDAA:1912 xref: EMAPA:17331 xref: EV:0100020 xref: FMA:7100 xref: GAID:568 xref: galen:Ventricle xref: MA:0000091 xref: MAT:0000497 xref: MESH:D006352 xref: NCIT:C12730 xref: SCTID:277699000 xref: TAO:0000009 xref: UMLS:C0018827 {source="ncithesaurus:Cardiac_Ventricle"} xref: VHOG:0000435 xref: Wikipedia:Ventricle_(heart) xref: XAO:0003193 xref: ZFA:0000009 is_a: UBERON:0004151 ! cardiac chamber relationship: contributes_to_morphology_of UBERON:0000948 ! heart relationship: develops_from UBERON:0006283 ! future cardiac ventricle relationship: immediate_transformation_of UBERON:0006283 {source="Bgee:AN"} ! future cardiac ventricle property_value: UBPROP:0000001 "A chamber of the heart that receives blood from one or more atria and pumps it by muscular contraction into the arteries.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010249", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "One of four heart chambers.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000009", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In the primitive vertebrate heart the four chambers are: 1. Sinus venosus (...) 2. Atrium (...) 3. Ventricle (...) 4. Conus arteriosus (...)[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000435", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.428", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002084 name: heart left ventricle namespace: uberon def: "A cardiac ventricle that is in the left side of the heart." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "cardiac left ventricle" EXACT [] synonym: "left cardiac ventricle" EXACT [] synonym: "left ventricle" EXACT [FMA:7101] synonym: "left ventricle of heart" EXACT [] synonym: "ventriculus sinister cordis" RELATED LATIN [Wikipedia:Left_ventricle] xref: BTO:0001629 xref: CALOHA:TS-0439 xref: EHDAA2:0002178 xref: EMAPA:17337 xref: FMA:7101 xref: galen:LeftVentricle xref: MA:0000092 xref: NCIT:C12871 xref: SCTID:244385005 xref: UMLS:C0225897 {source="ncithesaurus:Left_Ventricle"} xref: VHOG:0000718 xref: Wikipedia:Left_ventricle is_a: UBERON:0002082 ! cardiac ventricle is_a: UBERON:0035553 ! left cardiac chamber intersection_of: UBERON:0002082 ! cardiac ventricle intersection_of: in_left_side_of UBERON:0000948 ! heart relationship: connected_to UBERON:0004537 ! blood vasculature relationship: continuous_with UBERON:0000947 ! aorta relationship: develops_from UBERON:0004140 {source="GO"} ! primary heart field relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/20/Diagram_of_the_human_heart_%28cropped%29.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Thick-walled muscular chamber constituting the left border and apex of the heart. It receives oxygenated blood from the left atrium through the mitral orifice and send it off into the aorta. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000718", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The vertebrate heart initially forms as a tube from a population of precursor cells termed the first heart field (FHF). Cells from the adjacent second heart field (SHF) are then progressively added to the developing heart. In avian and mammalian hearts, the FHF contributes mainly to the left ventricle, whereas the SHF gives rise to the outflow tract and large portions of the right ventricle and atria. Both fields arise from common mesodermal progenitors, although the detailed lineage relationships between FHF and SHF remain uncertain.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000718", ontology="VHOG", source="DOI:10.1126/science.1190181 Stolfi A, Gainous TB, Young JJ, Mori A, Levine M, Christiaen L, Early chordate origins of the vertebrate second heart field. Science (2010)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI property_value: UBPROP:0000008 "In mammals continuous with aorta" xsd:string [Term] id: UBERON:0002085 name: interatrial septum namespace: uberon def: "A cardiac septum that divides the left and right atria of the heart." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "atrial septum" EXACT [] synonym: "atrium septum" EXACT [] synonym: "interatrial septal wall" EXACT [] xref: EHDAA2:0000838 xref: EHDAA:1896 xref: EMAPA:17011 xref: FMA:7108 xref: galen:InteratrialSeptum xref: MA:0000084 xref: NCIT:C32818 xref: SCTID:362016003 xref: UMLS:C0225836 {source="ncithesaurus:Interatrial_Septum"} xref: VHOG:0000385 xref: Wikipedia:Interatrial_septum is_a: UBERON:0002099 ! cardiac septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: adjacent_to UBERON:0002078 ! right cardiac atrium intersection_of: adjacent_to UBERON:0002079 ! left cardiac atrium relationship: adjacent_to UBERON:0002078 ! right cardiac atrium relationship: adjacent_to UBERON:0002079 ! left cardiac atrium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png" xsd:anyURI property_value: UBPROP:0000001 "The partition separating the right and left atria of the heart. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000385", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/interatrial+septum"} property_value: UBPROP:0000003 "The tetrapod clade develops a complete atrial septum and loses the fifth aortic arch altogether.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000385", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002089 name: thoracodorsal vein namespace: uberon def: "Companion vein of the thoracodorsal artery, draining the apical part of the latissimus dorsi and merging with the circumflex scapular vein to form a subscapular vein." [http://www.medilexicon.com/medicaldictionary.php?t=97559] subset: human_reference_atlas xref: EMAPA:37198 {source="MA:th"} xref: FMA:71213 xref: MA:0002238 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001112 ! latissimus dorsi muscle relationship: drains UBERON:0001112 ! latissimus dorsi muscle relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0000985 {source="FMA/obol"} ! axillary vein property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002090 name: postcranial axial skeleton namespace: uberon def: "The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]." [https://sourceforge.net/tracker/?func=detail&aid=2983975&group_id=76834&atid=974957, https://sourceforge.net/tracker/?func=detail&atid=1205376&aid=2983977&group_id=76834, ZFA:0000317] comment: previous some AOs had used the term 'axial skeleton' to include the skull. This is being resolved (see tracker items above). Status: MA - fixed. subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "axial skeleton" BROAD [FMA:71221, https://github.com/obophenotype/uberon/wiki/The-axial-skeleton] synonym: "post-cranial axial skeleton" EXACT [] xref: AAO:0000034 xref: EFO:0000942 xref: EHDAA2:0000161 xref: EHDAA:5049 xref: EMAPA:17214 xref: EMAPA:37721 {source="MA:th"} xref: FMA:71221 xref: MA:0002986 xref: MAT:0000148 xref: MIAA:0000148 xref: TAO:0000317 xref: VHOG:0000317 xref: VSAO:0000093 xref: XAO:0003073 xref: ZFA:0000317 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010912 ! subdivision of skeleton relationship: develops_from UBERON:0003089 ! sclerotome relationship: part_of UBERON:0005944 ! axial skeleton plus cranial skeleton relationship: part_of UBERON:0011138 ! postcranial axial skeletal system property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI property_value: UBPROP:0000001 "Skeletal subdivision of the central body axis including vertebrae, notochord, ribs, and sternum.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000093", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "The axial skeleton is formed by the vertebral column, a metameric, semi-flexible, arched bar located in the dorsal part of the trunk, and is formed by a series of cartilaginous or bony vertebrae. It provides suspension for the appendicular skeleton and protection for the spinal nerve cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000034", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The post-cranial structural components forming the long axis of the vertebrate body; usually consists of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000317", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The axial musculoskeletal system represents the plesiomorphic locomotor engine of the vertebrate body, playing a central role in locomotion. In craniates, the evolution of the postcranial skeleton is characterized by two major transformations. First, the axial skeleton became increasingly functionally and morphologically regionalized. Second, the axial-based locomotion plesiomorphic for craniates became progressively appendage-based with the evolution of extremities in tetrapods.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000317", ontology="VHOG", source="DOI:10.1186/1742-9994-8-4 Schilling N, Evolution of the axial system in craniates: morphology and function of the perivertebral musculature. Frontiers in Zoology (2011)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002091 name: appendicular skeleton namespace: uberon def: "Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003, Wikipedia:Appendicular_skeleton] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "appendicular skeleton" EXACT [] synonym: "entire appendicular skeleton" EXACT [https://github.com/obophenotype/uberon/issues/59] synonym: "paired fin skeleton" NARROW SENSU [] synonym: "skeleton appendiculare" RELATED LATIN [Wikipedia:Appendicular_skeleton] xref: AAO:0000747 xref: EFO:0000951 xref: EMAPA:32729 xref: FMA:71222 xref: MA:0000290 xref: MAT:0000278 xref: MIAA:0000278 xref: NCIT:C49477 xref: SCTID:322050006 xref: UMLS:C0222646 {source="ncithesaurus:Appendicular_Skeleton"} xref: VHOG:0001666 xref: VSAO:0000076 xref: Wikipedia:Appendicular_skeleton xref: XAO:0003166 is_a: UBERON:0010912 ! subdivision of skeleton relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: overlaps UBERON:0000026 ! appendage relationship: part_of UBERON:0011249 ! appendicular skeletal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7c/Appendicular_skeleton_diagram.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Appendages-and-the-appendicular-skeleton" xsd:anyURI property_value: UBPROP:0000001 "Skeletal subdivision consisting of all the skeletal elements in the pectoral and pelvic appendage complexes.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000076", ontology="VSAO", source="PSPUB:0000170", source="https://orcid.org/0000-0002-6601-2165"} property_value: UBPROP:0000001 "Skeletal system that consists of the paired fins (pectoral or pelvic fins).[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000027", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "The pectoral and pelvic girdles, which articulate with the axial skeleton, together with their associated limbs, the forelimbs and hind limbs, form the appendicular skeleton.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000747", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000012 "ontologies differ in whether they treat the term appendicular skeleton as being the entire set of bones in the limbs, or whether the fore and hind limbs/fins are treated as seperate appendicular skeletons. Here we follow FMA, and treat the appendicular skeleton as the sum total of skeletal elements in the organism (this is evidenced by the fact that in FMA, skeleton of left/right upper/lower limb is part_of a appendicular skeleton, and subtypes of 'subdivision of appendicular skeleton'). We have separate classes such as 'skeleton of limb', and 'skeleton of hindlimb' for the 4 parts of the appendicular skeleton. In future the ZFA/TAO classes may be moved." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002092 name: brain dura mater namespace: uberon def: "The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer." [MP:0009025] subset: pheno_slim synonym: "cranial dura mater" EXACT [FMA:71236] synonym: "dura mater cranialis" EXACT LATIN [FMA:71236, FMA:TA] synonym: "dura mater encephali" EXACT [] synonym: "dura mater of brain" EXACT [] xref: EMAPA:32668 xref: EV:0100313 xref: FMA:71236 xref: MA:0000815 xref: NCIT:C49332 xref: SCTID:309321003 xref: UMLS:C0459393 {source="ncithesaurus:Cerebral_Dura_Mater"} xref: VHOG:0000270 is_a: UBERON:0002363 ! dura mater is_a: UBERON:0003547 ! brain meninx intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0000955 ! brain property_value: UBPROP:0000001 "The outermost and densest membrane of the three mammalian meninges covering the brain and spinal cord. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000270", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000270", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002093 name: spinal dura mater namespace: uberon def: "A dura mater that is part of a spinal cord [Automatically generated definition]." [OBOL:automatic] subset: organ_slim subset: pheno_slim synonym: "dura mater of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "dura mater of spinal cord" EXACT [] synonym: "spinal cord dura mater" EXACT [] synonym: "spinal cord dura mater of neuraxis" EXACT [OBOL:automatic] xref: EMAPA:17806 xref: FMA:71237 xref: MA:0001132 xref: NCIT:C49799 xref: SCTID:362302001 xref: UMLS:C0228124 {source="ncithesaurus:Spinal_Cord_Dura_Mater"} xref: VHOG:0000411 is_a: UBERON:0002363 ! dura mater is_a: UBERON:0003292 ! meninx of spinal cord intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0002240 ! spinal cord property_value: UBPROP:0000001 "The outermost and densest membrane of the three mammalian meninges covering the brain and spinal cord. [Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier, adapted_from_Dorian_AF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000411", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000411", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002094 name: interventricular septum namespace: uberon def: "Cardiac septum which separates the right ventricle from the left ventricle.[FMA]." [FMA:7133] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "heart interventricular septum" EXACT [MA:0000085] synonym: "heart ventricular septum" EXACT [MA:0000085] synonym: "interventricular septum of heart" RELATED [BTO:0002483] synonym: "interventriculare cordis" RELATED [BTO:0002483] synonym: "intraventricular septum" RELATED [Wikipedia:Interventricular_septum] synonym: "s. interventriculare cordis" RELATED LATIN [Wikipedia:Interventricular_septum] synonym: "septum inferius" RELATED [Wikipedia:Interventricular_septum] synonym: "septum membranaceum" RELATED [Wikipedia:Interventricular_septum] synonym: "ventricle septum" RELATED [] synonym: "ventricular septum" RELATED [MA:0000085, Wikipedia:Interventricular_septum] xref: BTO:0002483 xref: EFO:0001956 xref: EHDAA:2603 xref: EMAPA:17333 xref: FMA:7133 xref: galen:InterventricularSeptum xref: MA:0000085 xref: NCIT:C32874 xref: SCTID:362019005 xref: UMLS:C0225870 {source="ncithesaurus:Interventricular_Septum"} xref: VHOG:0000386 xref: Wikipedia:Interventricular_septum is_a: UBERON:0002099 ! cardiac septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: adjacent_to UBERON:0002080 ! heart right ventricle intersection_of: adjacent_to UBERON:0002084 ! heart left ventricle relationship: adjacent_to UBERON:0002080 ! heart right ventricle relationship: adjacent_to UBERON:0002084 ! heart left ventricle property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The partition separating the right and left ventricles of the heart. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000386", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/interventricular+septum"} property_value: UBPROP:0000003 "The two most progressive vertebrate classes, the birds and mammals, have completed the ventricular septum and at long last have completely separated the two blood streams along the length of the major heart chambers. This development has obviously been brought about independently in the two cases, since mammals and birds have evolved independently from primitive reptiles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000386", ontology="VHOG", source="ISBN:978-0721676678 Romer AS, Vertebrate body (1970) p.430", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "involves the recruitment of myocardial cells as well as of non- muscular mesenchymal cells (Kaufman and Bard, 1999)" xsd:string {source="ISBN:0124020607"} [Term] id: UBERON:0002095 name: mesentery namespace: uberon def: "Anatomical organ component composed of a double layer of serous membrane that suspends a viscus from the body wall or connects adjacent viscera and in doing so conveys blood vessels, lymphatics and nerves to and from the viscera. Examples: greater omentum, broad ligament of uterus, sigmoid mesocolon." [FMA:7144, https://github.com/obophenotype/uberon/issues/85, Wikipedia:Mesentery, Wikipedia:Mesentery#Mesentery_.28general.29] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "generic mesentery" EXACT [Wikipedia:Mesentery] synonym: "mesentery (generic)" EXACT [Wikipedia:Mesentery] xref: AAO:0011061 xref: BTO:0001380 xref: EV:0100083 xref: FMA:7144 xref: GAID:21 xref: galen:Mesentery xref: MESH:D008643 xref: NCIT:C33103 xref: SCTID:362707009 xref: UMLS:C0025474 {source="ncithesaurus:Mesentery"} xref: Wikipedia:Mesentery#Mesentery_.28general.29 is_a: UBERON:0000042 ! serous membrane relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray1038.png" xsd:anyURI property_value: UBPROP:0000007 "mesenteric" xsd:string property_value: UBPROP:0000012 "in Uberon, this term is used in the generic sense, not necessarily restricted to the peritoneum, consistent with FMA. WP: 'In anatomy, the mesentery is the double layer of peritoneum that suspends the jejunum and ileum from the posterior wall of the abdomen. Its meaning, however, is frequently extended to include double layers of peritoneum connecting various components of the abdominal cavity.'. TODO - check. Consider FMA:259286 - Region of mesentery." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002097 name: skin of body namespace: uberon def: "The organ covering the body that consists of the dermis and epidermis." [UBERON:cjm] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: pheno_slim subset: uberon_slim synonym: "entire integument" RELATED [] synonym: "entire skin" EXACT [] synonym: "integument" RELATED [] synonym: "integumental organ" RELATED [] synonym: "pelt" RELATED [] synonym: "skin" RELATED [] synonym: "skin organ" EXACT [] xref: BTO:0001253 xref: CALOHA:TS-0934 xref: EFO:0000962 xref: EHDAA2:0001844 xref: EMAPA:17525 xref: FMA:7163 xref: galen:Skin xref: MESH:D012867 xref: MFMO:0000099 xref: NCIT:C12470 xref: SCTID:181469002 xref: UMLS:C1123023 {source="ncithesaurus:Skin"} xref: Wikipedia:Skin xref: XAO:0000023 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000062 ! organ is_a: UBERON:0004121 ! ectoderm-derived structure relationship: composed_primarily_of UBERON:0000014 ! zone of skin relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! embryonic skin basal layer relationship: part_of UBERON:0002199 ! integument property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6d/Skin.svg" xsd:anyURI property_value: IAO:0000232 "consider 'integumentary system' for invertebrates" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "MA uses the term skin to refer to what is called here: zone of skin" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002099 name: cardiac septum namespace: uberon def: "The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles." [MESH:A07.541.459] subset: pheno_slim subset: uberon_slim synonym: "cardiac septa" EXACT PLURAL [] synonym: "heart septa" EXACT PLURAL [] synonym: "heart septum" EXACT [] synonym: "septum of heart" EXACT [] synonym: "spiral septa" RELATED PLURAL [XAO:0004141] xref: EMAPA:35400 xref: FMA:7180 xref: GAID:562 xref: MA:0000083 xref: MESH:D006346 xref: NCIT:C49485 xref: SCTID:362014000 xref: UMLS:C0018819 {source="ncithesaurus:Heart_Septum"} is_a: UBERON:0003037 ! septum is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003037 ! septum intersection_of: part_of UBERON:0000948 ! heart relationship: adjacent_to UBERON:0004151 ! cardiac chamber relationship: contributes_to_morphology_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: UBPROP:0000008 "'Terrestrial vertebrates have divided hearts in which septae separate the oxygenated and deoxygenated blood within the pulmonary and systemic circulations'" xsd:string property_value: UBPROP:0000012 "in GO, septum morphogenesis is part of cardiac chamber morphogenesis; need to add axioms to infer this" xsd:string {external_ontology="GO"} [Term] id: UBERON:0002100 name: trunk namespace: uberon def: "Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present." [TAO:0001115, UBERONREF:0000006, Wikipedia:Torso] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "Rumpf" RELATED [BTO:0001493] synonym: "thoracolumbar region" EXACT [] synonym: "torso" EXACT [] synonym: "trunk region" EXACT [XAO:0000054] xref: AAO:0010339 xref: BILA:0000116 xref: BTO:0001493 xref: CALOHA:TS-1071 xref: EFO:0000966 xref: EMAPA:31857 xref: FMA:7181 xref: galen:Trunk xref: MA:0000004 xref: MAT:0000296 xref: MIAA:0000296 xref: NCIT:C33816 xref: SCTID:262225004 xref: TAO:0001115 xref: UMLS:C0460005 {source="ncithesaurus:Trunk"} xref: Wikipedia:Torso xref: XAO:0000054 xref: XAO:0003025 xref: ZFA:0001115 is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: has_part UBERON:0000915 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! thoracic segment of trunk relationship: has_part UBERON:0000916 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! abdomen relationship: part_of UBERON:0013702 ! body proper property_value: RO:0002171 UBERON:0000026 {exceptions="ZFA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"} property_value: RO:0002171 UBERON:0000033 property_value: UBPROP:0000001 "Organism subdivision that is the part of the body posterior to the head and anterior to the tail.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010339", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Organism subdivision which is the part of the body posterior to the head and anterior to the tail.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001115", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0002101 name: limb namespace: uberon def: "A paired appendage that is evolved from a paired fin. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the girdle and its parts." [UBERONREF:0000003] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "extremities" RELATED PLURAL [] synonym: "extremity" RELATED [] synonym: "flipper" NARROW SENSU [] synonym: "free limb" EXACT [FMA:24875] synonym: "limb sensu Vertebrata" EXACT [MAT:0000090] synonym: "pentadactyl limb" EXACT [] synonym: "tetrapod limb" EXACT [] xref: AAO:0010336 xref: AEO:0000172 xref: CALOHA:TS-0552 xref: EFO:0000876 xref: EHDAA2:0003172 xref: EHDAA:1697 xref: EHDAA:8273 xref: EMAPA:16405 xref: FMA:24875 xref: GAID:36 xref: galen:Extremity xref: MA:0000007 xref: MAT:0000090 xref: MIAA:0000090 xref: NCIT:C12429 xref: SCTID:243996003 xref: UMLS:C0015385 {source="ncithesaurus:Limb"} xref: VHOG:0000336 xref: VSAO:0000121 xref: Wikipedia:Limb xref: XAO:0003027 is_a: UBERON:0004708 {specialization_within="Sarcopterygians"} ! paired limb/fin intersection_of: UBERON:0000475 ! organism subdivision intersection_of: has_skeleton UBERON:0004381 ! skeleton of limb relationship: confers_advantage_in ENVO:00000446 relationship: develops_from UBERON:0004347 ! limb bud relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_skeleton UBERON:0004381 ! skeleton of limb relationship: only_in_taxon NCBITaxon:32523 {note="extends to stem tetrapods such as Eusthenopteron"} ! Tetrapoda property_value: UBPROP:0000001 "Organism subdivision that has as its parts the jointed appendages used for locomotion and manipulation.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010336", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000336", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002102 name: forelimb namespace: uberon def: "A (free) limb that is connected to a pectoral girdle. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pectoral girdle and its parts." [UBERONREF:0000003] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "anteriormost limb" EXACT [] synonym: "fore limb" EXACT [] synonym: "foreleg" RELATED [] synonym: "forelimb" EXACT [] synonym: "free part of upper limb" EXACT [FMA:24878] synonym: "free upper limb" EXACT [FMA:24878, UBERONREF:0000003] synonym: "membrum superius" EXACT LATIN [FMA:7183, FMA:TA] synonym: "pectoral flipper" NARROW SENSU [] synonym: "pectoral limb" EXACT [] synonym: "superior member" EXACT [] synonym: "upper extremity" EXACT [] synonym: "upper limb" EXACT [] xref: AAO:0000205 xref: BTO:0001729 xref: CALOHA:TS-2214 xref: EFO:0000882 xref: EHDAA2:0002133 xref: EHDAA:6208 xref: EMAPA:17412 xref: EV:0100014 xref: FMA:24878 xref: GAID:1215 xref: GAID:51 xref: galen:UpperExtremity xref: MA:0000025 xref: MAT:0000394 xref: MESH:D005552 xref: MIAA:0000394 xref: NCIT:C12671 xref: SCTID:182245002 xref: UMLS:C1140618 {source="ncithesaurus:Upper_Extremity"} xref: VHOG:0000338 xref: VSAO:0000148 xref: Wikipedia:Forelimb xref: XAO:0003030 is_a: UBERON:0002101 ! limb is_a: UBERON:0004710 ! pectoral appendage intersection_of: UBERON:0002101 ! limb intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: anterior_to UBERON:0002103 ! hindlimb relationship: develops_from UBERON:0005417 ! forelimb bud relationship: has_skeleton UBERON:0001440 ! forelimb skeleton relationship: part_of UBERON:0000153 ! anterior region of body property_value: IAO:0000232 "Note distinction between arm and forelimb. hand is part of forelimb, but not part of arm" xsd:string property_value: RO:0002171 UBERON:0002103 property_value: UBPROP:0000001 "Upper limb, which connects the manus with the pectoral girdle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000205", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000012 "note that this corresponds to FMA:'free upper limb' (a limb segment), NOT FMA:'upper limb'. Both MA and FMA consider shoulder (and shoulder bones) part of upper limb" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002103 name: hindlimb namespace: uberon def: "A (free) limb that is connected to a pelvic girdle region. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pelvic girdle and its parts." [UBERONREF:0000003, Wikipedia:Hindlimb, Wikipedia:Lower_limb] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "free lower limb" EXACT [FMA:24879, UBERONREF:0000003] synonym: "free part of lower limb" RELATED [FMA:24879] synonym: "hind limb" EXACT [] synonym: "hind-limb" EXACT [VSAO:0000150] synonym: "hindlimb" EXACT [] synonym: "inferior member" EXACT [] synonym: "lower extremity" RELATED [] synonym: "lower limb" EXACT [] synonym: "membrum inferius" EXACT LATIN [FMA:7184, FMA:TA] synonym: "membrum inferius" RELATED LATIN [Wikipedia:Lower_limb] synonym: "pelvic appendage" RELATED [] xref: AAO:0000219 xref: BTO:0002345 xref: CALOHA:TS-2215 xref: EFO:0000883 xref: EHDAA2:0001033 xref: EHDAA:6094 xref: EMAPA:17458 xref: EV:0100015 xref: FMA:24879 xref: GAID:1221 xref: GAID:38 xref: galen:LowerExtremity xref: MA:0000026 xref: MAT:0000395 xref: MESH:D006614 xref: MIAA:0000395 xref: NCIT:C12742 xref: NCIT:C77625 xref: SCTID:182281004 xref: UMLS:C0023216 {source="ncithesaurus:Lower_Extremity"} xref: UMLS:C1522391 {source="ncithesaurus:Hind_Limb"} xref: VHOG:0000337 xref: VSAO:0000150 xref: Wikipedia:Hindlimb xref: XAO:0003031 is_a: UBERON:0002101 ! limb is_a: UBERON:0004709 ! pelvic appendage intersection_of: UBERON:0002101 ! limb intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: develops_from UBERON:0005418 ! hindlimb bud relationship: has_skeleton UBERON:0001441 ! hindlimb skeleton relationship: part_of UBERON:0000154 ! posterior region of body property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray1239.png" xsd:anyURI property_value: UBPROP:0000001 "Lower limb, which connects the pes with the pelvic girdle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000219", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000337", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "crural" xsd:string property_value: UBPROP:0000012 "note that this corresponds to FMA:'free lower limb' (a limb segment), NOT 'lower limb'. Both MA and FMA consider shoulder (and shoulder bones) part of upper limb. Note that AAO class probably refers to skeleton" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002104 name: visual system namespace: uberon alt_id: UBERON:0007036 def: "The sensory system subserving the sense of vision." [NIFSTD:FMAID_7191] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "photosensory system" EXACT [BILA:0000140] synonym: "visual organ system" EXACT [] xref: AAO:0000632 xref: BILA:0000140 xref: EMAPA:36003 xref: FMA:7191 xref: http://uri.neuinfo.org/nif/nifstd/FMAID_7191 xref: MA:0002444 xref: NCIT:C12888 xref: SCTID:281831001 xref: TAO:0001127 xref: UMLS:C0587900 {source="ncithesaurus:Visual_System"} xref: Wikipedia:Visual_system xref: XAO:0003198 xref: ZFA:0001127 is_a: UBERON:0001032 ! sensory system relationship: capable_of_part_of GO:0007601 ! visual perception property_value: UBPROP:0000001 "The sensory system used for sight.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000632", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0002105 name: vestibulo-auditory system namespace: uberon def: "Sensory system responsible for the perception of spatial orientation and auditory stimuli." [ZFA:0001138] subset: functional_classification subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "auditory organ system" EXACT [] synonym: "auditory system" RELATED [] synonym: "auditory/vestibular system" RELATED [] synonym: "vestibuloauditory system" EXACT [] synonym: "vestibuloauditory system" RELATED [] xref: AAO:0000631 xref: EMAPA:36002 xref: EMAPA:37985 {source="MA:th"} xref: FMA:78500 xref: TAO:0001138 xref: XAO:0003195 xref: ZFA:0001138 is_a: UBERON:0001032 ! sensory system relationship: capable_of_part_of GO:0007605 ! sensory perception of sound property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d2/Anatomy_of_the_Human_Ear.svg" xsd:anyURI property_value: UBPROP:0000001 "The sensory system used for balance and hearing.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000631", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0002106 name: spleen namespace: uberon def: "The organ that functions to filter blood and to store red corpuscles and platelets." [ISBN:0-683-40008-8, MP:0000689] subset: efo_slim subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lien" RELATED LATIN [Wikipedia:Spleen] xref: AAO:0010395 xref: BTO:0001281 xref: CALOHA:TS-0956 xref: EFO:0000869 xref: EMAPA:18767 xref: EV:0100055 xref: FMA:7196 xref: GAID:1289 xref: galen:Spleen xref: MA:0000141 xref: MAT:0000085 xref: MESH:D013154 xref: MIAA:0000085 xref: NCIT:C12432 xref: SCTID:181279003 xref: TAO:0000436 xref: UMLS:C0037993 {source="ncithesaurus:Spleen"} xref: VHOG:0000120 xref: Wikipedia:Spleen xref: XAO:0000328 xref: ZFA:0000436 is_a: UBERON:0004177 ! hemopoietic organ is_a: UBERON:0005057 ! immune organ is_a: UBERON:0013765 ! digestive system element is_a: UBERON:0017672 ! abdominal viscera relationship: develops_from UBERON:0006293 ! spleen primordium relationship: only_in_taxon NCBITaxon:7776 {source="multiple sources - true spleen appear in jawed vertebrates"} ! Gnathostomata property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/d6/Illu_spleen.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "An organ involved in red blood cell filtration and immune response.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010395", ontology="AAO", source="AAO:BMZ"} property_value: UBPROP:0000003 "With the advent of clonal selection, the accumulation and segregation of T and B cells in specialized organs for antigen presentation became necessary, and indeed the spleen is found in all jawed vertebrates, but not in agnathans or invertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000120", ontology="VHOG", source="ISBN:978-0781765190 Paul WE, Fundamental Immunology (2008) p.94", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "lienal" xsd:string property_value: UBPROP:0000007 "splenic" xsd:string property_value: UBPROP:0000008 "In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron" xsd:string property_value: UBPROP:0000008 "Neither hagfish nor lampreys possess what might be considered a discrete and condensed spleen. Hagfish possess dispersed lymphoid tissue within the submucosa of the intestine (96) associated with the portal vein (97), whereas lymphoid tissue is associated with the typhlosole portion of the intestine in lampreys (96)" xsd:string {source="PMID:20959416"} property_value: UBPROP:0000009 "It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells" xsd:string [Term] id: UBERON:0002107 name: liver namespace: uberon def: "An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." [BTO:0000759, Wikipedia:Liver] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "iecur" RELATED LATIN [Wikipedia:Liver] synonym: "jecur" RELATED LATIN [Wikipedia:Liver] xref: AAO:0010111 xref: BTO:0000759 xref: CALOHA:TS-0564 xref: EFO:0000887 xref: EHDAA2:0000997 xref: EHDAA:2197 xref: EMAPA:16846 xref: EV:0100089 xref: FMA:7197 xref: GAID:288 xref: galen:Liver xref: MA:0000358 xref: MAT:0000097 xref: MESH:D008099 xref: MIAA:0000097 xref: NCIT:C12392 xref: SCTID:181268008 xref: TAO:0000123 xref: UMLS:C0023884 {source="ncithesaurus:Liver"} xref: VHOG:0000257 xref: Wikipedia:Liver xref: XAO:0000133 xref: ZFA:0000123 is_a: UBERON:0002365 {source="BTO", source="EHDAA2", source="GO-def"} ! exocrine gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005172 ! abdomen element is_a: UBERON:0006925 ! digestive system gland relationship: contributes_to_morphology_of UBERON:0002423 ! hepatobiliary system relationship: develops_from UBERON:0004161 {source="EHDAA2"} ! septum transversum relationship: develops_from UBERON:0008836 {source="http://www.stembook.org/node/512"} ! liver bud relationship: has_part UBERON:0004647 ! liver lobule relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: overlaps UBERON:0002405 {source="ZFA-weakened"} ! immune system relationship: part_of UBERON:0002423 {source="ZFA"} ! hepatobiliary system relationship: produces UBERON:0001970 ! bile relationship: site_of GO:0002384 ! hepatic immune response relationship: site_of GO:0005978 ! glycogen biosynthetic process relationship: site_of GO:0005980 ! glycogen catabolic process property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/64/Leber_Schaf.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Organ which secretes bile and participates in formation of certain blood proteins.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010111", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010111", ontology="AAO"} property_value: UBPROP:0000003 "All vertebrates possess a liver (reference 1); Later in craniate evolution, an anterior gill arch was transformed into jaws, and many new types of feeding subsequently evolved.(...) A liver evolved that, among its many functions, stores considerable energy as glycogen or lipid (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000257", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.526, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "hepatic" xsd:string property_value: UBPROP:0000008 "An organ sometimes referred to as a liver is found associated with the digestive tract of the primitive chordate Amphioxus. However, this is an enzyme secreting gland, not a metabolic organ, and it is unclear how truly homologous it is to the vertebrate liver. The zebrafish liver differs from the mammalian liver in that the hepatocytes are not clearly organized in cords or lobules and the typical portal triads are not apparent. In addition, the zebrafish liver does not have Kuppfer cells. Furthermore, a clear distinction can be made between the male and female liver in the adult zebrafish. The female hepatocytes are very basophilic (Figure 15c) as a result of the production of vitellogenin (Van der Ven et al. 2003)." xsd:string property_value: UBPROP:0000008 "The liver is found in all vertebrates, and is typically the largest visceral organ. Its form varies considerably in different species, and is largely determined by the shape and arrangement of the surrounding organs. Nonetheless, in most species it is divided into right and left lobes; exceptions to this general rule include snakes, where the shape of the body necessitates a simple cigar-like form. The internal structure of the liver is broadly similar in all vertebrates." xsd:string property_value: UBPROP:0000009 "secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]." xsd:string property_value: UBPROP:0000012 "Only ZFA considers this part_of immune system - we weaken this to an overlaps relation, as in general it's only a subset of cells that have clear immune function." xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0002108 name: small intestine namespace: uberon def: "Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]." [ISBN:0073040584, Wikipedia:Small_intestine] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "anterior intestine" RELATED [] synonym: "intestinum tenue" RELATED LATIN [BTO:0000651, Wikipedia:Small_intestine] synonym: "mid intestine" RELATED [] synonym: "small bowel" EXACT [] synonym: "small intestine" EXACT [] xref: AAO:0010397 xref: BTO:0000651 xref: CALOHA:TS-0942 xref: EFO:0000841 xref: EMAPA:32834 xref: EV:0100072 xref: FMA:7200 xref: GAID:313 xref: galen:SmallIntestine xref: MA:0000337 xref: MAT:0000047 xref: MESH:D007421 xref: MIAA:0000047 xref: NCIT:C12386 xref: SCTID:181250005 xref: TAO:0001323 xref: UMLS:C0021852 {source="ncithesaurus:Small_Intestine"} xref: VHOG:0000055 xref: Wikipedia:Small_intestine xref: XAO:0000130 xref: ZFA:0001323 is_a: UBERON:0004921 {order="2", source="cjm"} ! subdivision of digestive tract is_a: UBERON:0013765 ! digestive system element relationship: contributes_to_morphology_of UBERON:0000160 ! intestine relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000160 ! intestine property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/82/Stomach_colon_rectum_diagram.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The terminal region of the mid intestine is comprised of specialized enterocytes that appear to play a role in mucosal immunity. Wallace et al, 2005.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001323", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Intestinal surface area also is increased in amphibians and reptiles by internal folds and occasionally by a few villi. The intestine can be divided into a small intestine and a slightly wider large intestine.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000055", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.566", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002109 name: pair of nares namespace: uberon def: "Pair of nostrils." [Wikipedia:Nares] subset: uberon_slim synonym: "nares" RELATED [] synonym: "nares set" EXACT [] synonym: "nostrils" EXACT [] synonym: "pair of nostrils" EXACT [] synonym: "set of nares" RELATED [FMA:72005] xref: FMA:72005 xref: Wikipedia:Nares is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034925 ! anatomical collection intersection_of: UBERON:0034925 ! anatomical collection intersection_of: has_member UBERON:0000003 {cardinality="2"} ! naris relationship: has_member UBERON:0000003 ! naris relationship: has_part UBERON:0000003 ! naris relationship: part_of UBERON:0000004 ! nose property_value: RO:0002161 NCBITaxon:7745 {source="http://webs.lander.edu/rsfox/invertebrates/ammocoetes.html"} property_value: UBPROP:0000012 "this is a 'set of anatomical planes' in FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002110 name: gallbladder namespace: uberon def: "An organ that aids digestion and stores bile produced by the liver[WP]." [Wikipedia:Gallbladder] comment: Rats do not have a gallbladder, but produce bile. The bile flows directly from the liver through the (hepatic) bile duct into the small intestine (Hebel and Stromberg, 1988) subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cholecyst" EXACT [WikipediaVersioned:Gallbladder&oldid=1092217922] synonym: "gall bladder" EXACT [] synonym: "vesica biliaris" RELATED LATIN [Wikipedia:Gallbladder] synonym: "vesica fellea" RELATED LATIN [Wikipedia:Gallbladder] xref: AAO:0010114 xref: BTO:0000493 xref: CALOHA:TS-0394 xref: EFO:0000853 xref: EHDAA2:0000699 xref: EHDAA:8062 xref: EMAPA:17202 xref: EV:0100090 xref: FMA:7202 xref: galen:Gallbladder xref: MA:0000356 xref: MAT:0000072 xref: MESH:D005704 xref: MIAA:0000072 xref: NCIT:C12377 xref: SCTID:181269000 xref: TAO:0000208 xref: UMLS:C0016976 {source="ncithesaurus:Gallbladder"} xref: VHOG:0000221 xref: Wikipedia:Gallbladder xref: XAO:0000135 xref: ZFA:0000208 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0013765 ! digestive system element is_a: UBERON:0017672 ! abdominal viscera is_a: UBERON:0018707 {source="BTO"} ! bladder organ relationship: contributes_to_morphology_of UBERON:0001173 ! biliary tree relationship: develops_from UBERON:0004912 ! biliary bud relationship: develops_from UBERON:0006242 {evidence="definitional"} ! gallbladder primordium relationship: part_of UBERON:0002294 ! biliary system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/b/b1/GallbladderAnatomy-en.svg" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/f/f4/Abdomal_organs.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:10114 {source="ISBN:9780120749034"} property_value: RO:0002161 NCBITaxon:8801 {source="GOC:mr", source="ISBN:9781840761122"} property_value: RO:0002161 NCBITaxon:8930 {source="GOC:mr", source="ISBN:9781840761122"} property_value: UBPROP:0000001 "Membranous muscular sac in which the bile from the liver remains stored until it is required. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000221", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Organ attached to the liver which stores bile and empties into the duodenum via the bile duct as needed for digestion.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010114", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship type change: differentiates_from endoderm (AAO:0000139) CHANGED TO: develops_from endoderm (UBERON:0000925)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010114", ontology="AAO"} property_value: UBPROP:0000003 "The presence of a gallbladder appears to be a primitive trait. It is found in most fish and all adult reptiles and amphibians and has been well conserved in mammals, for the most part.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000221", ontology="VHOG", source="DOI:10.1002/(SICI)1097-0029(19970915)38:6<571::AID-JEMT3>3.0.CO;2-I Oldham-Ott CK, Gilloteaux J, Comparative morphology of the gallbladder and biliary tract in vertebrates: Variation in structure, homology in function and gallstones. Microscopy research and technique (1997)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002111 name: artery smooth muscle tissue namespace: uberon def: "A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]." [OBOL:automatic] synonym: "arterial smooth muscle" EXACT [BTO:0000087] synonym: "arterial smooth muscle cell" RELATED [BTO:0000087] synonym: "artery smooth muscle" EXACT [] synonym: "artery smooth muscle tissue" EXACT [] synonym: "smooth muscle of artery" EXACT [FMA:72024] xref: BTO:0000087 xref: CALOHA:TS-1198 xref: EMAPA:36285 xref: FMA:72024 xref: MA:0000708 xref: NCIT:C49195 xref: UMLS:C1706851 {source="ncithesaurus:Artery_Smooth_Muscle_Tissue"} is_a: UBERON:0004237 ! blood vessel smooth muscle is_a: UBERON:0004695 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0001637 ! artery [Term] id: UBERON:0002112 name: smooth muscle of esophagus namespace: uberon def: "A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "esophageal smooth muscle" EXACT [] synonym: "esophagus involuntary muscle" EXACT [OBOL:automatic] synonym: "esophagus non-striated muscle" EXACT [OBOL:automatic] synonym: "esophagus smooth muscle" EXACT [] synonym: "esophagus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gullet involuntary muscle" EXACT [OBOL:automatic] synonym: "gullet non-striated muscle" EXACT [OBOL:automatic] synonym: "gullet smooth muscle" EXACT [OBOL:automatic] synonym: "gullet smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of esophagus" EXACT [OBOL:automatic] synonym: "involuntary muscle of gullet" EXACT [OBOL:automatic] synonym: "involuntary muscle of oesophagus" EXACT [OBOL:automatic] synonym: "non-striated muscle of esophagus" EXACT [OBOL:automatic] synonym: "non-striated muscle of gullet" EXACT [OBOL:automatic] synonym: "non-striated muscle of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus involuntary muscle" EXACT [OBOL:automatic] synonym: "oesophagus non-striated muscle" EXACT [OBOL:automatic] synonym: "oesophagus smooth muscle" RELATED [] synonym: "oesophagus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of gullet" EXACT [OBOL:automatic] synonym: "smooth muscle of oesophagus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of esophagus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gullet" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of oesophagus" EXACT [OBOL:automatic] xref: EMAPA:35323 xref: FMA:72025 xref: MA:0001573 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001043 ! esophagus relationship: contributes_to_morphology_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0003832 ! esophagus muscle [Term] id: UBERON:0002113 name: kidney namespace: uberon def: "A paired organ of the urinary tract which has the production of urine as its primary function." [http://anatomy.uams.edu/anatomyhtml/kidney.html, Wikipedia:Kidney] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "reniculate kidney" NARROW SENSU [Wikipedia:Reniculate_kidney] xref: AAO:0000250 xref: BTO:0000671 xref: CALOHA:TS-0510 xref: EFO:0000929 xref: EMAPA:17373 xref: EV:0100096 xref: FMA:7203 xref: GAID:423 xref: galen:Kidney xref: MA:0000368 xref: MAT:0000119 xref: MESH:D007668 xref: MIAA:0000119 xref: NCIT:C12415 xref: SCTID:181414000 xref: UMLS:C0022646 {source="ncithesaurus:Kidney"} xref: Wikipedia:Kidney xref: XAO:0003267 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000489 ! cavitated compound organ is_a: UBERON:0005172 ! abdomen element is_a: UBERON:0015212 ! lateral structure relationship: contributes_to_morphology_of UBERON:0001008 ! renal system relationship: develops_from UBERON:0003918 {evidence="definitional"} ! kidney mesenchyme relationship: develops_from UBERON:0005095 ! kidney rudiment relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0011143 {source="FMA"} ! upper urinary tract property_value: RO:0002171 UBERON:0000160 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of either of a pair of structures lying on either side of the dorsal aorta in which fluid balance is regulated and waste is excreted out in the form of urine.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000250", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000007 "renal" xsd:string property_value: UBPROP:0000202 FMA:264815 [Term] id: UBERON:0002114 name: duodenum namespace: uberon def: "The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one)." [ISBN:0815318960, Wikipedia:Duodenum] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "proximal intestine" RELATED [BTO:0000365] synonym: "upper intestine" RELATED [BTO:0000365] xref: AAO:0010402 xref: BTO:0000365 xref: CALOHA:TS-0214 xref: EFO:0000851 xref: EMAPA:18852 xref: EV:0100073 xref: FMA:7206 xref: GAID:284 xref: galen:Duodenum xref: MA:0000338 xref: MAT:0000044 xref: MESH:D004386 xref: MIAA:0000044 xref: NCIT:C12263 xref: SCTID:181247007 xref: UMLS:C0013303 {source="ncithesaurus:Duodenum"} xref: VHOG:0000052 xref: Wikipedia:Duodenum xref: XAO:0000236 is_a: UBERON:0004921 {order="3", source="cjm"} ! subdivision of digestive tract relationship: continuous_with UBERON:0001166 ! pylorus relationship: contributes_to_morphology_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0002108 ! small intestine relationship: proximalmost_part_of UBERON:0002108 ! small intestine property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b3/Tractus_intestinalis_duodenum.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:7955 {source="ZFA:0000348"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The fixed portion of the small intestine deeply lodged in the posterior wall of the abdomen and extending from the pylorus to the beginning of the jejunum. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000052", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "duodenal" xsd:string property_value: UBPROP:0000008 "In fish, the divisions of the small intestine are not as clear, and the terms anterior intestine or proximal intestine may be used instead of duodenum." xsd:string {scope="NCBITaxon:32443", source="Wikipedia:Duodenum"} property_value: UBPROP:0000008 "In humans, the duodenum is a hollow jointed tube about 10-15 inches (25-38 centimetres) long connecting the stomach to the jejunum. It begins with the duodenal bulb and ends at the ligament of Treitz." xsd:string {scope="NCBITaxon:9606", source="Wikipedia:Duodenum"} [Term] id: UBERON:0002118 name: right ovary namespace: uberon def: "An ovary that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37367 {source="MA:th"} xref: FMA:7213 xref: MA:0001705 xref: NCIT:C33487 xref: SCTID:280123002 xref: UMLS:C0227873 {source="ncithesaurus:Right_Ovary"} is_a: UBERON:0000992 ! ovary is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000992 ! ovary intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0002119 name: left ovary namespace: uberon def: "An ovary that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37366 {source="MA:th"} xref: FMA:7214 xref: MA:0001704 xref: NCIT:C32969 xref: SCTID:280124008 xref: UMLS:C0227874 {source="ncithesaurus:Left_Ovary"} is_a: UBERON:0000992 ! ovary is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000992 ! ovary intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI property_value: UBPROP:0000008 "In some elasmobranchs, the left ovary does not mature, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo" xsd:string {source="Wikipedia:Ovary#In_other_animals"} [Term] id: UBERON:0002120 name: pronephros namespace: uberon alt_id: UBERON:0005794 def: "In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]." [GO:0048793, Wikipedia:Pronephros] comment: Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104 subset: efo_slim subset: organ_slim subset: uberon_slim synonym: "archinephron" RELATED [BTO:0001541] synonym: "embryonic kidney" RELATED [BTO:0001541] synonym: "pronephric kidney" EXACT [XAO:0002000] synonym: "pronephron" RELATED [BTO:0001541] xref: AAO:0011089 xref: BTO:0001541 xref: EFO:0000927 xref: EHDAA2:0001570 xref: EHDAA:1017 xref: EMAPA:16579 xref: FMA:72170 xref: MAT:0000117 xref: MESH:D060910 xref: MIAA:0000117 xref: NCIT:C34280 xref: SCTID:308804007 xref: TAO:0000151 xref: UMLS:C0231048 {source="ncithesaurus:Pronephros"} xref: VHOG:0000037 xref: Wikipedia:Pronephros xref: XAO:0002000 xref: ZFA:0000151 is_a: UBERON:0002113 {source="GO"} ! kidney is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0005721 {source="ZFA"} ! pronephric mesoderm relationship: develops_from UBERON:0005754 ! rostral part of nephrogenic cord relationship: located_in UBERON:0003887 {source="OG"} ! intraembryonic coelom property_value: UBPROP:0000001 "A kidney formed of nephric tubules arising in the anterior region of the nephric ridge; forms only as a transient embryonic structure. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Kardong_KV, Vertebrates:_Comparative_Anatomy, p.748][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000037", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Organ that serves as a transient kidney, providing osmoregulation during early developmental stages and then degenerating during metamorphosis.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011089", ontology="AAO", source="XAO:curator"} property_value: UBPROP:0000001 "The embryonic kidney, present at the level of the third somite, is composed of two glomeruli fused at the midline, two pronephric tubules, and paired bilateral pronephric ducts that modify the composition of the blood filtrate before delivering it to the cloaca for excretion.Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000151", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In all vertebrate embryos, the kidney begins with the differentiation of a few renal tubules from the anterior end of the nephric ridge overlying the pericardial cavity. (...) This early-developing embryonic kidney is called the pronephros.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000037", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.637", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "pronephric" xsd:string [Term] id: UBERON:0002128 name: superior olivary complex namespace: uberon def: "A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system." [ISBN:0-19-502694-2, Wikipedia:Superior_olivary_complex] subset: uberon_slim synonym: "nucleus olivaris superior" EXACT LATIN [FMA:72247, FMA:TA] synonym: "regio olivaris superioris" RELATED LATIN [NeuroNames:569] synonym: "superior olivary nuclei" EXACT [FMA:72247] synonym: "superior olivary nucleus" RELATED INCONSISTENT [FMA:72247] synonym: "superior olivary nucleus (Barr & Kiernan)" RELATED [NeuroNames:569] synonym: "superior olive" RELATED INCONSISTENT [FMA:72247, ISBN:0-19-502694-2] xref: BAMS:SOC xref: BIRNLEX:1307 xref: DHBA:12462 xref: EMAPA:35840 xref: EV:0100263 xref: FMA:72247 xref: HBA:9177 xref: MA:0001026 xref: MBA:398 xref: MESH:D065832 xref: neuronames:569 {source="BIRNLEX:1307"} xref: UMLS:C0175427 {source="BIRNLEX:1307"} xref: VHOG:0001381 xref: Wikipedia:Superior_olivary_complex is_a: UBERON:0007245 ! nuclear complex of neuraxis is_a: UBERON:0019263 ! gray matter of hindbrain relationship: part_of UBERON:0003023 {source="NIFSTD"} ! pontine tegmentum relationship: part_of UBERON:0016490 ! auditory system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/46/Gray713.png" xsd:anyURI property_value: RO:0002171 UBERON:0002597 {source="ABA"} property_value: RO:0002171 UBERON:0006840 {source="ABA"} property_value: RO:0002171 UBERON:0007634 {source="ABA"} property_value: UBPROP:0000008 "In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound[GO:0021718]" xsd:string property_value: UBPROP:0000008 "The SOC displays a significant interspecies variation, being largest in bats and rodents and smaller in primates." xsd:string [Term] id: UBERON:0002148 name: locus ceruleus namespace: uberon def: "The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]." [GAID:577, GO:0021703, Wikipedia:Locus_ceruleus] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "blue nucleus" EXACT [BIRNLEX:905] synonym: "caerulean nucleus" EXACT [] synonym: "loci coeruleus" RELATED PLURAL [ZFA:0000539] synonym: "locus caeruleus" EXACT [BIRNLEX:905] synonym: "locus cinereus" RELATED [BTO:0001408] synonym: "locus coeruleu" EXACT [] synonym: "locus coeruleus" EXACT [] synonym: "locus coeruleus (Vicq d'Azyr)" RELATED [NeuroNames:583] synonym: "Noradrenergic cell group A6" EXACT [Noradrenergic_cell_group_A6&oldid=981960774] synonym: "nucleus caeruleus" EXACT LATIN [FMA:72478, FMA:TA] synonym: "nucleus loci caerulei" RELATED LATIN [NeuroNames:583] synonym: "nucleus of locus caeruleus" EXACT [] synonym: "nucleus pigmentosus pontis" EXACT [BIRNLEX:905] synonym: "substantia ferruginea" EXACT [BIRNLEX:905] xref: BAMS:CAE xref: BAMS:LC xref: BIRNLEX:905 xref: BM:Pons-LC xref: BTO:0001408 xref: DHBA:12819 xref: DMBA:16972 xref: EFO:0001963 xref: EMAPA:35502 xref: FMA:72478 xref: GAID:577 xref: HBA:9148 xref: MA:0001017 xref: MBA:147 xref: MESH:D008125 xref: NCIT:C97333 xref: neuronames:583 {source="BIRNLEX:905"} xref: SCTID:369016004 xref: TAO:0000539 xref: UMLS:C0023951 {source="ncithesaurus:Locus_Coeruleus", source="BIRNLEX:905"} xref: Wikipedia:Locus_ceruleus xref: ZFA:0000539 is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus is_a: UBERON:8440015 ! noradrenergic cell groups relationship: capable_of GO:0048243 ! norepinephrine secretion relationship: part_of UBERON:0003023 {notes="check ZFA", source="NIFSTD"} ! pontine tegmentum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Gray709.png" xsd:anyURI property_value: editor_note "TODO - check ZFA/pons. also GO says part of dorsorostral pons" xsd:string property_value: RO:0002171 UBERON:0002047 {source="ABA"} property_value: RO:0002171 UBERON:0002267 {source="ABA"} property_value: RO:0002171 UBERON:0002587 {source="ABA"} property_value: RO:0002171 UBERON:0003004 {source="ABA"} [Term] id: UBERON:0002149 name: superior salivatory nucleus namespace: uberon def: "Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703)." [BIRNLEX:1131] subset: uberon_slim synonym: "nucleus salivarius superior" RELATED LATIN [NeuroNames:590] synonym: "nucleus salivatorius cranialis" RELATED LATIN [NeuroNames:590] synonym: "nucleus salivatorius rostralis" RELATED LATIN [NeuroNames:590] synonym: "nucleus salivatorius superior" RELATED LATIN [NeuroNames:590] synonym: "superior salivary nucleus" EXACT [GO:0021753] xref: BAMS:SSN xref: BAMS:SuS xref: BIRNLEX:1131 xref: DHBA:12435 xref: EHDAA2:0004646 xref: EMAPA:37756 {source="MA:th"} xref: FMA:72482 xref: HBA:9194 xref: MA:0001027 xref: MBA:462 xref: neuronames:590 {source="BIRNLEX:1131"} xref: SCTID:369028007 xref: UMLS:C0175447 {source="BIRNLEX:1131"} xref: Wikipedia:Superior_salivatory_nucleus is_a: UBERON:0000126 ! cranial nerve nucleus is_a: UBERON:0004133 ! salivatory nucleus is_a: UBERON:0007635 ! nucleus of medulla oblongata relationship: develops_from UBERON:0010125 ! future superior salivatory nucleus relationship: immediate_transformation_of UBERON:0010125 {evidence="definitional"} ! future superior salivatory nucleus relationship: part_of UBERON:0003023 ! pontine tegmentum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6b/Gray788.png" xsd:anyURI property_value: RO:0002171 UBERON:0002143 {source="ABA"} property_value: RO:0002171 UBERON:0002147 {source="ABA"} property_value: RO:0002171 UBERON:0002151 {source="ABA"} property_value: RO:0002171 UBERON:0002633 {source="ABA"} property_value: RO:0002171 UBERON:0002682 {source="ABA"} property_value: RO:0002171 UBERON:0002963 {source="ABA"} property_value: RO:0002171 UBERON:0002968 {source="ABA"} property_value: RO:0002171 UBERON:0003011 {source="ABA"} property_value: RO:0002171 UBERON:0007632 {source="ABA"} [Term] id: UBERON:0002165 name: endocardium namespace: uberon alt_id: UBERON:0006225 def: "The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]." [GO:0003157] comment: fixed in GO to reflect FMA. See email to David/Varsha June 18 2010 subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "endocardial lining" EXACT [EMAPA:32686] synonym: "endocardial tissue" EXACT [EMAPA:17868] synonym: "heart endocardial tissue" RELATED [VHOG:0000084] synonym: "heart endocardium" EXACT [] xref: AAO:0010408 xref: BTO:0000387 xref: CALOHA:TS-2075 xref: EFO:0000821 xref: EHDAA2:0004153 xref: EMAPA:17868 xref: EMAPA:32686 xref: EV:0100021 xref: FMA:7280 xref: GAID:550 xref: galen:Endocardium xref: MA:0000076 xref: MAT:0000455 xref: MESH:D004699 xref: NCIT:C13004 xref: SCTID:362013006 xref: TAO:0001320 xref: UMLS:C0014124 {source="ncithesaurus:Endocardium"} xref: VHOG:0000084 xref: Wikipedia:Endocardium xref: XAO:0000066 xref: ZFA:0001320 is_a: UBERON:0002523 ! tunica intima is_a: UBERON:0005983 ! heart layer relationship: develops_from UBERON:0007280 ! presumptive endocardium relationship: has_part UBERON:0005316 ! endocardial endothelium relationship: immediate_transformation_of UBERON:0007280 {source="Bgee:AN"} ! presumptive endocardium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray493.png" xsd:anyURI property_value: UBPROP:0000001 "Layer that lines the lumen of the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001320", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Part of the heart comprised of thin serous membrane, composed of endothelial tissue, that lines the interior of the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010408", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Tunica intima which has as its parts the endothelium of endocardium and the fibroelastic connective tissue that surrounds the cavity of a cardiac chamber." xsd:string {source="FMA:7280"} [Term] id: UBERON:0002166 name: endocardium of atrium namespace: uberon def: "Endocardium that is part of the atrium." [ZFIN:curator] subset: pheno_slim subset: vertebrate_core synonym: "atrial endocardium" EXACT [] synonym: "atrium endocardial tissue" RELATED [VHOG:0000606] synonym: "atrium endocardium" EXACT [] synonym: "atrium of heart endocardium" EXACT [OBOL:automatic] synonym: "Cardiac atria endocardium" EXACT [OBOL:automatic] synonym: "cardiac atrium endocardium" EXACT [OBOL:automatic] synonym: "endocardium of atrium of heart" EXACT [OBOL:automatic] synonym: "endocardium of Cardiac atria" EXACT [OBOL:automatic] synonym: "endocardium of cardiac atrium" EXACT [OBOL:automatic] synonym: "endocardium of heart atrium" EXACT [OBOL:automatic] synonym: "heart atrium endocardium" EXACT [OBOL:automatic] xref: EMAPA:32745 xref: FMA:7284 xref: MA:0000077 xref: SCTID:192001005 xref: TAO:0002169 xref: VHOG:0000606 xref: ZFA:0001614 is_a: UBERON:0002165 ! endocardium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: contributes_to_morphology_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002081 ! cardiac atrium [Term] id: UBERON:0002167 name: right lung namespace: uberon def: "Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]." [FMA:FMA, Wikipedia:Right_lung] subset: pheno_slim subset: uberon_slim xref: EHDAA2:0001730 xref: EHDAA:4969 xref: EMAPA:17661 xref: FMA:7309 xref: MA:0000426 xref: NCIT:C33483 xref: SCTID:361967000 xref: UMLS:C0225706 {source="ncithesaurus:Right_Lung"} xref: VHOG:0000301 xref: Wikipedia:Right_lung is_a: UBERON:0002048 ! lung intersection_of: UBERON:0002048 ! lung intersection_of: in_right_side_of UBERON:0000170 ! pair of lungs relationship: in_right_side_of UBERON:0000170 ! pair of lungs property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/32/Gray972.png" xsd:anyURI property_value: UBPROP:0000003 "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000301", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.210", source="http://bgee.unil.ch/"} property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0002168 name: left lung namespace: uberon def: "Lung which consists of the left upper lobe and left lower lobe.[FMA]." [FMA:FMA, Wikipedia:Left_lung] subset: pheno_slim subset: uberon_slim xref: EHDAA2:0000943 xref: EHDAA:4947 xref: EMAPA:17653 xref: FMA:7310 xref: MA:0000425 xref: NCIT:C32967 xref: SCTID:361982005 xref: UMLS:C0225730 {source="ncithesaurus:Left_Lung"} xref: VHOG:0000618 xref: Wikipedia:Left_lung is_a: UBERON:0002048 ! lung intersection_of: UBERON:0002048 ! lung intersection_of: in_left_side_of UBERON:0000170 ! pair of lungs relationship: in_left_side_of UBERON:0000170 ! pair of lungs property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/dd/Gray973.png" xsd:anyURI property_value: UBPROP:0000003 "Lungs had already developed as paired ventral pockets from the intestine in the ancestor of Osteognathostomata.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000618", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.210", source="http://bgee.unil.ch/"} property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0002185 name: bronchus namespace: uberon def: "The upper conducting airways of the lung; these airways arise from the terminus of the trachea." [ISBN:0-397-51047-0, MESH:A04.411.125, MGI:cwg, MP:0002264] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "bronchi" EXACT PLURAL [] synonym: "bronchial tissue" RELATED [BTO:0001340] synonym: "bronchial trunk" EXACT [FMA:7409] xref: BTO:0001340 xref: CALOHA:TS-1229 xref: EFO:0000932 xref: EMAPA:32689 xref: EV:0100041 xref: FMA:7409 xref: GAID:346 xref: MA:0000436 xref: MAT:0000133 xref: MESH:D001980 xref: MIAA:0000133 xref: NCIT:C12683 xref: SCTID:181215002 xref: UMLS:C0006255 {source="ncithesaurus:Bronchus"} xref: VHOG:0000262 xref: Wikipedia:Bronchus xref: XAO:0000121 is_a: UBERON:0000117 ! respiratory tube relationship: located_in UBERON:0002224 ! thoracic cavity relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/18/Respiratory_system_complete_numbered.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:8507 {source="Wikipedia"} property_value: UBPROP:0000001 "Each of the two primary divisions of the trachea leading respectively into the right and the left lung. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000262", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "bronchial" xsd:string property_value: UBPROP:0000008 "In humans, the main bronchus is histologically identical to trachea; 2ary and 3ary bronchi are not; epithelium becomes simple columnar, goblet cell number decreases, elastic fibers in lamina propria increases, distribution more uniform. Muscular layer between mucosa and submucosa appears. cartilage rings become discontinuous plates connected by fibrous connective tissue" xsd:string [Term] id: UBERON:0002186 name: bronchiole namespace: uberon def: "The conducting airway of the lungs found terminal to the bronchi; these structures contain neither cartilage nor mucous-secreting glands; the epithelium of the bronchioles becomes thinner with each branching." [ISBN:0-397-51047-0, MGI:cwg, MP:0002267] comment: In some texts/references/ontologies, bronchiole has been used as an exact synonym of 'lobular bronchiole'. However, a 'lobular bronchiole' is a segment of a bronchiole. {xref="https://github.com/obophenotype/uberon/issues/2795"} subset: pheno_slim subset: uberon_slim synonym: "bronchioli" RELATED PLURAL [] synonym: "bronchiolus" RELATED [BTO:0002375] xref: BTO:0002375 xref: CALOHA:TS-2003 xref: EHDAA:8171 xref: EHDAA:8183 xref: EHDAA:8199 xref: EHDAA:8221 xref: EMAPA:32697 xref: FMA:7410 xref: MA:0000422 xref: MESH:D055745 xref: NCIT:C12684 xref: SCTID:278982001 xref: UMLS:C0006270 {source="ncithesaurus:Bronchiole"} xref: VHOG:0000675 xref: Wikipedia:Bronchiole is_a: UBERON:0000117 ! respiratory tube relationship: branching_part_of UBERON:0007196 {source="FMA"} ! tracheobronchial tree relationship: part_of UBERON:0007196 ! tracheobronchial tree relationship: part_of UBERON:0010368 {source="ncit"} ! pulmonary lobule property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI property_value: UBPROP:0000007 "bronchiolar" xsd:string property_value: UBPROP:0000010 "lacks submucosa and cartilage plates; they have 3 layers: mucosa, muscular layer and outer layer" xsd:string {source="ISBN:0123813611"} property_value: UBPROP:0000012 "In FMA2 and FMA3, lobular bronchiole is an exact synonym of bronchiole; however, there are two distinct terms for the corresponding epithelium." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002187 name: terminal bronchiole namespace: uberon def: "The last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls." [ISBN:0-397-51047-0, MGI:cwg, MP:0002268] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "bronchioli terminalis" RELATED LATIN [Wikipedia:Terminal_bronchiole] synonym: "bronchiolus terminalis" EXACT LATIN [] synonym: "terminal bronchiole tube" RELATED [] xref: BTO:0003223 xref: EMAPA:36282 xref: FMA:7411 xref: MA:0000424 xref: NCIT:C33754 xref: SCTID:278981008 xref: UMLS:C0225666 {source="ncithesaurus:Terminal_Bronchiole"} xref: Wikipedia:Terminal_bronchiole is_a: UBERON:0002186 ! bronchiole property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002190 name: subcutaneous adipose tissue namespace: uberon alt_id: UBERON:0008875 def: "A portion of adipose tissue that is part of the hypodermis, beneath the dermis." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim synonym: "fatty layer of subcutaneous tissue" EXACT [FMA:74315] synonym: "fatty layer of superficial fascia" RELATED [FMA:74315] synonym: "hypodermis fat layer" EXACT [MP:0011156] synonym: "panniculus adiposus" BROAD [MP:0011156] synonym: "panniculus adiposus (tela subcutanea)" EXACT LATIN [FMA:74315, FMA:TA] synonym: "panniculus adiposus telae subcutaneae" EXACT LATIN [FMA:74315, FMA:TA] synonym: "subcutaneous fat" RELATED [BTO:0004042] synonym: "subcutaneous fat layer" EXACT [MP:0011156] xref: BTO:0004042 xref: EMAPA:35829 xref: FMA:74315 xref: MA:0000473 is_a: UBERON:0001013 ! adipose tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0002072 ! hypodermis relationship: contributes_to_morphology_of UBERON:0002072 ! hypodermis relationship: part_of UBERON:0002072 ! hypodermis property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "the superficial portion of the subcutaneous tissue which is specialized for fat storage[MP:0011156]" xsd:string {source="MP:0011156"} [Term] id: UBERON:0002193 name: hemolymphoid system namespace: uberon def: "Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs." [http://orcid.org/0000-0002-6601-2165] synonym: "haemolymphoid system" RELATED [] synonym: "hematolymphoid system" EXACT [] synonym: "lymphomyeloid complex" EXACT [] xref: CALOHA:TS-2018 xref: EHDAA2:0004615 xref: EMAPA:18765 xref: FMA:74562 xref: MA:0000013 is_a: UBERON:0000467 {source="MA"} ! anatomical system relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: UBERON:0002199 name: integument namespace: uberon def: "The dermis, epidermis and hypodermis." [Wikipedia:Integument] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "dermal system" RELATED [BTO:0000634] synonym: "dermis plus epidermis plus hypodermis" EXACT [] synonym: "dermoid system" RELATED [BTO:0000634] synonym: "integumentum commune" EXACT LATIN [FMA:74657, FMA:TA] synonym: "skin" RELATED [] synonym: "skin and subcutaneous tissue" EXACT [] synonym: "skin plus hypodermis" EXACT [] synonym: "tegument" RELATED [BTO:0000634] synonym: "the integument" EXACT [FMA:74657] synonym: "vertebrate integument" RELATED [] xref: AAO:0000239 xref: BTO:0000634 xref: EMAPA:37504 {source="MA:th"} xref: FMA:74657 xref: galen:Integument xref: TAO:0000368 xref: VSAO:0000029 xref: Wikipedia:Integument xref: ZFA:0000368 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0011216 {source="FMA"} ! organ system subdivision relationship: bounding_layer_of UBERON:0000468 ! multicellular organism relationship: has_part UBERON:0002072 ! hypodermis relationship: has_part UBERON:0002097 ! skin of body relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0002416 {source="FMA"} ! integumental system property_value: IAO:0000232 "in FMA intergument = skin+superficial fascia(hypodermis), skin=dermis+epidermis+hair_nail. Note that the definition provided here excludes the more general sense of the term 'integument' used in invertebrates; consider 'integumental system'. Note that the VSAO class appears to include adnexa by its definition." xsd:string property_value: UBPROP:0000001 "Anatomical system that protects the body from damage, comprising the skin and its appendages.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000239", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Surface structure that is the outer protective covering of the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000029", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "The outer protective barrier that separates the animal from its aquatic environment. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000368", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000007 "integumental" xsd:string property_value: UBPROP:0000007 "integumentary" xsd:string [Term] id: UBERON:0002200 name: vasculature of head namespace: uberon def: "Vasculature that is part of a head [Automatically generated definition]." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "adult head vascular network" EXACT [OBOL:automatic] synonym: "adult head vasculature" EXACT [OBOL:automatic] synonym: "cranial vasculature" EXACT [] synonym: "head vascular network" EXACT [OBOL:automatic] synonym: "head vasculature" RELATED [] synonym: "vascular network of adult head" EXACT [OBOL:automatic] synonym: "vascular network of head" EXACT [OBOL:automatic] synonym: "vasculature of adult head" EXACT [OBOL:automatic] xref: EFO:0003656 xref: FMA:74710 xref: TAO:0001267 xref: XAO:0004152 xref: ZFA:0001267 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0002201 name: vasculature of trunk namespace: uberon def: "A vasculature that is part of a trunk [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "torso vascular network" EXACT [OBOL:automatic] synonym: "torso vasculature" EXACT [OBOL:automatic] synonym: "trunk vascular network" EXACT [OBOL:automatic] synonym: "trunk vasculature" EXACT [] synonym: "vascular network of torso" EXACT [OBOL:automatic] synonym: "vascular network of trunk" EXACT [OBOL:automatic] synonym: "vasculature of torso" EXACT [OBOL:automatic] xref: FMA:74712 xref: TAO:0005024 xref: ZFA:0005024 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0002202 name: submucosa of trachea namespace: uberon def: "A submucosa that is part of a trachea." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "submucosa of windpipe" EXACT [OBOL:automatic] synonym: "submucous layer of trachea" RELATED [BTO:0002115] synonym: "trachea submucosa" EXACT [] synonym: "tracheal submucosa" EXACT [] synonym: "windpipe submucosa" EXACT [OBOL:automatic] xref: BTO:0002115 xref: EMAPA:35879 xref: FMA:7472 xref: MA:0001860 xref: NCIT:C49307 xref: SCTID:4419000 xref: UMLS:C0225586 {source="ncithesaurus:Trachea_Submucosa"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004777 ! respiratory system submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0003126 ! trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002203 name: vasculature of eye namespace: uberon def: "Vasculature that is part of the eye region." [https://sourceforge.net/tracker/?func=detail&aid=3489658&group_id=76834&atid=994726, OBOL:automatic] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "eye vascular network" EXACT [OBOL:automatic] synonym: "eye vasculature" RELATED [] synonym: "ocular blood vessel" EXACT [ZFA:0007057] synonym: "ocular vasculature" EXACT [] synonym: "optic vasculature" RELATED [] synonym: "vascular network of eye" EXACT [OBOL:automatic] xref: FMA:74743 xref: SCTID:123846009 xref: TAO:0007057 xref: ZFA:0007057 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002200 ! vasculature of head is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: develops_from UBERON:0003314 {source="ISBN:0781772214"} ! eye mesenchyme relationship: part_of UBERON:0000019 ! camera-type eye property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "not part of the eye in ZFA. Note this changed to a blood vessel in ZFA" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0002204 name: musculoskeletal system namespace: uberon def: "Anatomical system that consists of the muscular and skeletal systems." [https://github.com/obophenotype/uberon/issues/77, VSAO:0000031, VSAO:curator] subset: uberon_slim synonym: "musculo-skeletal system" EXACT [] xref: AAO:0010546 xref: CALOHA:TS-1311 xref: EMAPA:32714 xref: EV:0100139 xref: FMA:7482 xref: GAID:98 xref: MA:0002418 xref: MESH:D009141 xref: NCIT:C12754 xref: SCTID:278858007 xref: UMLS:C0026860 {source="ncithesaurus:Musculoskeletal_System"} xref: VHOG:0001275 xref: VSAO:0000031 xref: Wikipedia:Musculoskeletal_system xref: XAO:0000168 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0002294 ! biliary system disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of_part_of GO:0040011 ! locomotion relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_developmental_contribution_from UBERON:0000926 {notes="check ctenophore"} ! mesoderm relationship: has_part UBERON:0000383 ! musculature of body relationship: has_part UBERON:0001434 ! skeletal system relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall property_value: UBPROP:0000001 "Anatomical system that provides locomotion and physical support to the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010546", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "There are more than 50,000 extant vertebrate species, representing over 500 million years of evolution. During that time, the vertebrate musculoskeletal systems have adapted to aquatic, terrestrial, fossorial, and arboreal lifestyles, while simultaneously retaining functionally integrated axial and appendicular skeletal systems.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001275", ontology="VHOG", source="DOI:10.1002/jez.b.21246 Shearman RM, Burke AC, The lateral somitic frontier in ontogeny and phylogeny. Journal of Experimental Zoology (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "musculoskeletal" xsd:string [Term] id: UBERON:0002209 name: fibrous joint namespace: uberon def: "Nonsynovial joint in which the articulating bones or cartilages are connected by ligaments. Examples: sagittal suture, inferior tibiofibular syndesmosis, gomphosis.[FMA]." [FMA:FMA, Wikipedia:Fibrous_joint] subset: uberon_slim subset: vertebrate_core synonym: "articulatio fibrosa" EXACT [] synonym: "junctura fibrosa" RELATED LATIN [Wikipedia:Fibrous_joint] xref: AEO:0000178 xref: EHDAA2:0003178 xref: EMAPA:35344 xref: FMA:7492 xref: MA:0000321 xref: SCTID:37772004 xref: TAO:0005156 xref: Wikipedia:Fibrous_joint xref: ZFA:0005156 is_a: UBERON:0011134 {source="FMA"} ! nonsynovial joint relationship: has_part CL:0002320 {source="AEO"} ! connective tissue cell property_value: UBPROP:0000001 "A joint where fibrous tissue such as ligament connects two calcified tissues.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005156", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0002210 name: syndesmosis namespace: uberon def: "Fibrous joint in which the articulating bones or cartilages of the vertebral column and the limbs as well as articulating ossicles, are connected by skeletal ligaments or membranes. Examples: Intervertebral syndesmosis, inferior tibiofibular joint.[FMA]." [FMA:FMA, Wikipedia:Syndesmosis] subset: uberon_slim xref: EMAPA:37465 {source="MA:th"} xref: FMA:7494 xref: MA:0001500 xref: SCTID:89358004 xref: Wikipedia:Syndesmosis is_a: UBERON:0002209 ! fibrous joint is_a: UBERON:0002213 ! cartilaginous joint [Term] id: UBERON:0002213 name: cartilaginous joint namespace: uberon def: "Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]." [FMA:FMA, Wikipedia:Cartilaginous_joint] subset: uberon_slim subset: vertebrate_core synonym: "articulatio cartilaginea" EXACT [] synonym: "junctura cartilaginea" RELATED LATIN [Wikipedia:Cartilaginous_joint] xref: EMAPA:36581 xref: FMA:7496 xref: MA:0000320 xref: SCTID:58442004 xref: TAO:0005155 xref: Wikipedia:Cartilaginous_joint xref: ZFA:0005155 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011134 {source="FMA"} ! nonsynovial joint intersection_of: UBERON:0011134 ! nonsynovial joint intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0002215 name: synchondrosis namespace: uberon def: "Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA]." [FMA:FMA, Wikipedia:Synchondrosis] subset: pheno_slim subset: uberon_slim synonym: "cartilago epiphysialis" EXACT LATIN [FMA:7497, FMA:TA] synonym: "epiphysial cartilage" RELATED [FMA:7497] synonym: "primary cartilaginous joint" EXACT [FMA:7497] xref: EMAPA:35846 xref: FMA:7497 xref: MA:0001501 xref: SCTID:42903008 xref: Wikipedia:Synchondrosis is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002209 ! fibrous joint is_a: UBERON:0002213 ! cartilaginous joint intersection_of: UBERON:0002209 ! fibrous joint intersection_of: composed_primarily_of UBERON:0001994 ! hyaline cartilage tissue relationship: composed_primarily_of UBERON:0001994 ! hyaline cartilage tissue property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/76/Gray297.png" xsd:anyURI property_value: editor_note "consider adding link to hyaline cartilage" xsd:string property_value: editor_note "WP considers epiphyseal plates as subtypes of this" xsd:string [Term] id: UBERON:0002216 name: symphysis namespace: uberon def: "Cartilaginous joint in which the articulating bones or cartilages are connected by fibrocartilage. Examples: pubic symphysis, intervertebral symphysis, manubriosternal joint.[FMA]." [FMA:FMA, Wikipedia:Symphysis] subset: uberon_slim synonym: "secondary cartilaginous joint" EXACT [FMA:7498] xref: EMAPA:37758 {source="MA:th"} xref: FMA:7498 xref: MA:0001504 xref: SCTID:1584001 xref: Wikipedia:Symphysis is_a: UBERON:0002209 {source="MA"} ! fibrous joint is_a: UBERON:0002213 {source="FMA"} ! cartilaginous joint property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray298.png" xsd:anyURI property_value: editor_note "consider adding fibrocartilage class" xsd:string [Term] id: UBERON:0002217 name: synovial joint namespace: uberon def: "Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]." [FMA:7501, Wikipedia:Synovial_joint] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "articulatio synoviale" EXACT [] synonym: "diarthrodial joints" RELATED PLURAL [ZFA:0005153] synonym: "diarthroses" EXACT PLURAL [ZFA:0005153] synonym: "diarthrosis" EXACT [] synonym: "diarthrosis joint" EXACT [] xref: AEO:0000183 xref: CALOHA:TS-2138 xref: EHDAA2:0003183 xref: FMA:7501 xref: galen:SynovialJoint xref: MA:0000322 xref: NCIT:C32461 xref: SCTID:113234001 xref: TAO:0005153 xref: Wikipedia:Synovial_joint xref: ZFA:0005153 is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: surrounded_by UBERON:0001484 ! articular capsule disjoint_from: UBERON:0011134 ! nonsynovial joint relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: surrounded_by UBERON:0001484 ! articular capsule property_value: UBPROP:0000001 "Is a joint that is located at the point of contact of articulating bones allowing movement. The joint has a capsule containing synovial fluid surrounding the articulating bone surfaces.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005153", ontology="TAO", source="ZFIN:Curator"} [Term] id: UBERON:0002224 name: thoracic cavity namespace: uberon def: "The part of the coelemic cavity lumen that is enclosed by the walls of the thorax." [UBERON:cjm, Wikipedia:Thoracic_cavity] subset: pheno_slim subset: uberon_slim synonym: "cavitas thoracis" EXACT LATIN [Wikipedia:Thoracic_cavity] synonym: "cavity of chest" EXACT [] synonym: "cavity of thorax" EXACT [] synonym: "chest cavity" EXACT [] synonym: "pectoral cavity" EXACT [] synonym: "space of thoracic compartment" EXACT [FMA:7565] synonym: "thoracic lumen" EXACT [] xref: EMAPA:36497 xref: FMA:7565 xref: GAID:93 xref: MA:0000032 xref: MESH:D035423 xref: NCIT:C12905 xref: SCTID:243949006 xref: UMLS:C0230139 {source="ncithesaurus:Thoracic_Cavity"} xref: Wikipedia:Thoracic_cavity is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000915 ! thoracic segment of trunk intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen relationship: luminal_space_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0002323 ! coelemic cavity lumen property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/ce/Gray846.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI property_value: UBPROP:0000008 "In many species, the diaphragm separates thoracic and abdominal cavities" xsd:string [Term] id: UBERON:0002228 name: rib namespace: uberon def: "An intersegmental rod-shaped bone that forms in the peritoneal membrane and attach to the vertebral parapophyses." [Wikipedia:Rib, ZFIN:curator] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "dorsal rib" RELATED [] synonym: "pleural rib" RELATED [] synonym: "ribs" RELATED PLURAL [TAO:0000538] xref: AAO:0000545 xref: CALOHA:TS-2209 xref: EFO:0003066 xref: EMAPA:18010 xref: FMA:7574 xref: GAID:245 xref: galen:Rib xref: MA:0000315 xref: MESH:D012272 xref: NCIT:C12782 xref: SCTID:302523002 xref: TAO:0000538 xref: UMLS:C0035561 {source="ncithesaurus:Rib"} xref: VHOG:0001154 xref: Wikipedia:Rib xref: ZFA:0000538 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0015019 ! rib endochondral element intersection_of: UBERON:0015019 ! rib endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0006288 {evidence="definitional"} ! rib cartilage element relationship: part_of UBERON:0003252 {gci_filler="NCBITaxon:314146", gci_relation="part_of", notes="Euarchontoglires"} ! thoracic rib cage property_value: UBPROP:0000001 "Endochondral bone that is intersegmental and rod-shaped, forming in the peritoneal membrane and attached to the vertebral parapophyses. Ribs protect and support internal organs.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000538", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Endochondral, rodlike element that articulates with the transverse process and parapophysis (double-headed rib), or with the transverse process only (single-headed rib); it extends into the body wall and provides a site for muscle attachment.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000545", ontology="AAO", source="AAO:Pugener_2002"} property_value: UBPROP:0000007 "costal" xsd:string property_value: UBPROP:0000008 "In most vertebrates, ribs surround the chest. In some species, especially snakes, ribs may provide support and protection for the entire body" xsd:string property_value: UBPROP:0000009 "They protect and support internal organs and enable lungs to expand by expanding the chest." xsd:string [Term] id: UBERON:0002234 name: proximal phalanx of manus namespace: uberon def: "A proximal phalanx that is part of a finger [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "hand proximal phalanx" EXACT [MA:0001395] synonym: "phalanx proximalis manus" EXACT LATIN [FMA:75816, FMA:TA] synonym: "proximal manual phalanx" EXACT [] synonym: "proximal phalanx of finger" EXACT [FMA:75816] synonym: "proximal phalanx of fore digit" EXACT [] synonym: "proximal phalanx of hand" EXACT [] synonym: "proximal phalanx of manual digit" EXACT [] xref: EMAPA:37307 {source="MA:th"} xref: FMA:75816 xref: MA:0001395 xref: NCIT:C52786 xref: SCTID:181986000 xref: SCTID:361325003 xref: UMLS:C0730117 {source="ncithesaurus:Proximal_Phalanx_of_Hand"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0004302 ! proximal phalanx intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: proximally_connected_to UBERON:0002374 ! metacarpal bone [Term] id: UBERON:0002237 name: true rib namespace: uberon def: "A rib that is ventrally connected to the sternum." [ISBN:0073040584, Wikipedia:True_ribs] synonym: "costa vera" EXACT [] synonym: "costae verae" RELATED PLURAL [Wikipedia:True_ribs] xref: EMAPA:37774 {source="MA:th"} xref: FMA:7592 xref: MA:0001419 xref: SCTID:368044009 xref: Wikipedia:True_ribs is_a: UBERON:0002228 ! rib intersection_of: UBERON:0002228 ! rib intersection_of: connected_to UBERON:0000975 ! sternum relationship: connected_to UBERON:0000975 ! sternum relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3d/Gray115.png" xsd:anyURI [Term] id: UBERON:0002240 name: spinal cord namespace: uberon def: "Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO)." [BIRNLEX:1709] subset: cumbo subset: efo_slim subset: human_reference_atlas subset: major_organ subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cerebro-cerebellar fissure" RELATED [NeuroNames:22] synonym: "cerebrocerebellar fissure" RELATED [NeuroNames:22] synonym: "fissura cerebro-cerebellaris" RELATED LATIN [NeuroNames:22] synonym: "fissura cerebrocerebellaris" RELATED LATIN [NeuroNames:22] synonym: "medulla spinalis" RELATED LATIN [BTO:0001279, Wikipedia:Spinal_cord] synonym: "SpC" RELATED ABBREVIATION [] synonym: "spinal cord structure" RELATED [ZFA:0000075] synonym: "spinal medulla" RELATED [BTO:0001279] xref: AAO:0010151 xref: BAMS:SP xref: BAMS:Spinal xref: BIRNLEX:1709 xref: BM:SpC xref: BTO:0001279 xref: CALOHA:TS-0953 xref: DHBA:12890 xref: DMBA:17651 xref: EFO:0000110 xref: EHDAA2:0001255 xref: EHDAA:2863 xref: EMAPA:17577 xref: EV:0100316 xref: FMA:7647 xref: GAID:695 xref: MA:0000216 xref: MAT:0000183 xref: MESH:D013116 xref: MIAA:0000183 xref: NCIT:C12464 xref: neuronames:22 {source="BIRNLEX:1709"} xref: SCTID:180959008 xref: TAO:0000075 xref: UMLS:C0037925 {source="ncithesaurus:Spinal_Cord", source="BIRNLEX:1709"} xref: VHOG:0000601 xref: Wikipedia:Spinal_cord xref: XAO:0000020 xref: ZFA:0000075 is_a: UBERON:0000489 ! cavitated compound organ is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: develops_from UBERON:0003076 ! posterior neural tube relationship: develops_from UBERON:0006241 ! future spinal cord relationship: has_developmental_contribution_from UBERON:0003853 {evidence="definitional"} ! spinal cord neural crest relationship: has_part CL:0005000 {source="ZFA"} ! spinal cord interneuron relationship: immediate_transformation_of UBERON:0006241 {evidence="definitional"} ! future spinal cord relationship: part_of UBERON:0001017 ! central nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/58/Spinal_cord_direv.svg" xsd:anyURI property_value: editor_note "TODO - add superclass to unify with VNC?" xsd:string property_value: RO:0002171 UBERON:0000955 {exceptions="ZFA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Part of the central nervous system which descends from the hindbrain within the vertebral column.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010151", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000601", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.165", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002241 name: chondrocranium namespace: uberon def: "Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]." [http://medical-dictionary.thefreedictionary.com/chondrocranium, Wikipedia:Chondrocranium] subset: vertebrate_core synonym: "calvarium" RELATED [MA:0000317] synonym: "neurocranium" RELATED INCONSISTENT [MA:0000317] xref: AAO:0010169 xref: EHDAA2:0000243 xref: EMAPA:17681 xref: TAO:0001424 xref: VHOG:0000288 xref: Wikipedia:Chondrocranium xref: ZFA:0001424 is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system relationship: overlaps UBERON:0001703 ! neurocranium property_value: editor_note "we follow the standard evolutionary classification and treat this as endoskeletal. This means what MA calls 'chondrocranium' must in fact be neurocranium, as it includes parts of the dermatocranium (e.g. frontal, parietal)" xsd:string property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and composed of cartilage and cartilage replacement bones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010169", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and composed of cartilage and cartilage replacement bones.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001424", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000007 "chondrocranial" xsd:string property_value: UBPROP:0000008 "covers the brain dorsally in chondrichthyans" xsd:string [Term] id: UBERON:0002244 name: premaxilla namespace: uberon alt_id: UBERON:0002253 def: "One of the bones of the upper jaw situated between and in front of the maxillae[VHOG]." [VHOG:0000426, Wikipedia:Incisive_bone, Wikipedia:Premaxilla] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "incisive bone" RELATED [Wikipedia:Incisive_bone] synonym: "os incisivum" RELATED [Wikipedia:Premaxilla] synonym: "premaxilla bone" RELATED [Wikipedia:Premaxilla] synonym: "premaxillae" EXACT PLURAL [] synonym: "premaxillary" EXACT [PHENOSCAPE:ad] synonym: "premaxillary bone" RELATED [Wikipedia:Premaxilla] xref: AAO:0000461 xref: EHDAA:6962 xref: EHDAA:8033 xref: EMAPA:17641 xref: FMA:76869 xref: FMA:77231 xref: MA:0001493 xref: SCTID:308884009 xref: TAO:0000567 xref: VHOG:0000426 xref: Wikipedia:Incisive_bone xref: ZFA:0000567 is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0008907 ! dermal bone is_a: UBERON:0011597 ! bone of upper jaw relationship: develops_from UBERON:0011628 ! early premaxilla relationship: immediate_transformation_of UBERON:0011628 {source="Bgee:AN"} ! early premaxilla relationship: part_of UBERON:0003113 {source="ISBN:0073040584"} ! dermatocranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4a/Gray160.png" xsd:anyURI property_value: editor_note "requires checking embryonic vs adult; isa fetal organ part in FMA; adult bone of upper jaw in AAO and ZFA; split. Note that we have loops if we add develops_from UBERON:0005620 primary palate" xsd:string property_value: RO:0002161 NCBITaxon:7901 {source="Wikipedia"} property_value: UBPROP:0000001 "Dermal bone that forms the anteriormost element of the upper jaw. It articulates with the maxilla posterodorsally and its antimere medially. The premaxilla is paired.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000567", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "One of the bones of the upper jaw situated between and in front of the maxillae. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000426", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Paired, intramembranous bones located at the anterior end of the skull; they form the anterior-most segment of the maxillary arch.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000461", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: overlaps inter-premaxillary joint (TAO:0001950)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000567", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: overlaps mesethmoid-premaxillary joint (TAO:0001676)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000567", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: overlaps premaxillary-maxillary joint (TAO:0002260)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000567", ontology="TAO"} property_value: UBPROP:0000003 "(...) in all higher vertebrates a premaxilla is present (...) (reference 1); Although the presence of a tooth-bearing outer buccal arcade (premaxilla, maxilla, dentary) is cited as a common character of Osteichthyes, dipnoans lack all three bones (...) (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000426", ontology="VHOG", source="DOI:10.1017/S0022215100025585 O'Malley JF, Evolution of the nasal cavities and sinuses in relation to function. The Journal of Laryngology and Otology (1924), ISBN:978-3540428541 Kapoor BG, Bhavna Khanna, Ichthyology Handbook (2004) p.105", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002257 name: ventral horn of spinal cord namespace: uberon def: "The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]." [GO:0021517, https://sourceforge.net/tracker/?group_id=36855&atid=440764, MP:0005112, Wikipedia:Anterior_horn_of_spinal_cord] subset: pheno_slim subset: vertebrate_core synonym: "anterior column" RELATED [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "anterior column of the spinal cord" RELATED [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "anterior gray column of spinal cord" EXACT [FMA:256541] synonym: "anterior gray horn of spinal cord" EXACT [FMA:256541] synonym: "anterior grey column of spinal cord" EXACT [] synonym: "anterior horn" EXACT [BIRNLEX:2668] synonym: "anterior horn (spinal cord)" RELATED [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "columna grisea anterior medullae spinalis" EXACT LATIN [FMA:256541, FMA:TA] synonym: "cornu anterius medullae spinalis" RELATED LATIN [Wikipedia:Anterior_horn_of_spinal_cord] synonym: "spinal cord anterior horn" EXACT [BIRNLEX:2668] synonym: "spinal cord ventral horn" EXACT [] synonym: "ventral gray column of spinal cord" EXACT [FMA:256541] synonym: "ventral gray matter of spinal cord" EXACT [FMA:256541] synonym: "ventral grey column of spinal cord" EXACT [] synonym: "ventral grey horn" EXACT [BIRNLEX:2668] synonym: "ventral horn of the spinal cord" RELATED [BAMS:VH] synonym: "ventral horn spinal cord" EXACT [ZFA:0000702] synonym: "ventral horns spinal cord" RELATED PLURAL [VHOG:0001288] synonym: "ventral region of spinal cord" EXACT [] synonym: "ventral spinal cord" EXACT [] xref: BAMS:VH xref: BIRNLEX:2668 xref: BTO:0005151 xref: EMAPA:18575 xref: EMAPA:35794 xref: FMA:256541 xref: MA:0001134 xref: NCIT:C33859 xref: neuronames:1751 xref: SCTID:279443000 xref: TAO:0000702 xref: UMLS:C0228569 {source="BIRNLEX:2668"} xref: UMLS:C0228590 {source="ncithesaurus:Ventral_Horn_of_the_Spinal_Cord"} xref: VHOG:0001288 xref: Wikipedia:Anterior_horn_of_spinal_cord xref: ZFA:0000702 is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0016550 ! spinal cord column relationship: contributes_to_morphology_of UBERON:0002315 ! gray matter of spinal cord relationship: has_part CL:0000100 ! motor neuron relationship: in_lateral_side_of UBERON:0002315 {source="FMA-abduced-lr"} ! gray matter of spinal cord relationship: part_of UBERON:0002315 ! gray matter of spinal cord property_value: UBPROP:0000001 "The anterior horn of the spinal cord (or anterior cornu, or anterior column, or ventral horn) is the ventral (front) grey matter section of the spinal cord. The anterior horn contains motor neurons that affect the axial muscles while the posterior horn receives information regarding touch and sensation. The anterior horn is where the cell bodies of alpha motorneurons are located[Wikipedia:Anterior_horn_of_spinal_cord]." xsd:string {source="Wikipedia:Anterior_horn_of_spinal_cord"} [Term] id: UBERON:0002268 name: olfactory organ namespace: uberon def: "An organ that houses olfactory neurons and is responsible for the sense of smell. Examples include the vertebrate nose and the Drosophila dorsal organ." [UBERON:cjm] subset: functional_classification synonym: "main olfactory organ" NARROW [] synonym: "olfactory neuroepithelium" RELATED [BTO:0001772] synonym: "olfactory organ" EXACT [BTO:0001772] synonym: "olfactory sense organ" EXACT [] synonym: "olfactory sensory organ" EXACT [FBbt:00005158] synonym: "organ olfactus" RELATED [BTO:0001772] synonym: "organum olfactorium" RELATED [BTO:0001772] synonym: "primary olfactory organ" NARROW [] xref: AAO:0010180 xref: BTO:0001772 xref: FBbt:00005158 xref: FMA:77659 xref: VHOG:0000287 xref: XAO:0000273 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: capable_of GO:0050911 ! detection of chemical stimulus involved in sensory perception of smell relationship: has_part CL:0000207 ! olfactory receptor cell relationship: overlaps UBERON:0005725 ! olfactory system property_value: editor_note "An olfactory organ overlaps with the olfactory system, because some parts of the nose (e.g. nasal skeleton) are parts of the skeletal system, which is spatially disjoint" xsd:string property_value: UBPROP:0000012 "fma general anatomical term. xao has no subtypes (but Johnstons organ develops from this). An olfactory organ overlaps with the olfactory system, because some parts of the nose (e.g. nasal skeleton) are parts of the skeletal system, which is spatially disjoint" xsd:string [Term] id: UBERON:0002275 name: reticular formation namespace: uberon def: "A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 )." [NeuroNames:1223] subset: uberon_slim synonym: "brain stem reticular formation" EXACT [NeuroNames:1223] synonym: "brainstem reticular formation" EXACT [MA:0003185, NeuroNames:1223] synonym: "reticular formation (classical)" EXACT [NeuroNames:1223] synonym: "reticular formation of the brainstem" EXACT [NeuroNames:1223] xref: BAMS:RET xref: EMAPA:35188 xref: FMA:77719 xref: MA:0003185 xref: MESH:D012154 xref: neuronames:1223 xref: NLX:143558 xref: SCTID:361552007 xref: Wikipedia:Reticular_formation is_a: UBERON:0002616 ! regional part of brain relationship: part_of UBERON:0002298 ! brainstem property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9b/Gray701.png" xsd:anyURI property_value: IAO:0000232 "this class denotes the generic structure, and not a specific one such as medullary or pontine reticular formation." xsd:string property_value: UBPROP:0000008 "It is essential for governing some of the basic functions of higher organisms, and is one of the phylogenetically oldest portions of the brain." xsd:string property_value: UBPROP:0000012 "FMA has a spinal cord reticular formation but we follow NNs (classical) to restrict this to brainstem structures. This means we also include the MA class for brainstem reticular formation here. FMA has subtypes of reticular formation but we treat this as a composite structure" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002294 name: biliary system namespace: uberon def: "Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree)." [Wikipedia:Biliary_system] subset: pheno_slim subset: uberon_slim synonym: "biliary apparatus" EXACT [FMA:79646] synonym: "biliary tract" RELATED [FMA:79646, MA:0001273] xref: FMA:79646 xref: GAID:279 xref: MA:0001273 xref: MESH:D001659 xref: NCIT:C12678 xref: SCTID:361354009 xref: Wikipedia:Biliary_system is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0011216 ! organ system subdivision intersection_of: UBERON:0011216 ! organ system subdivision intersection_of: capable_of GO:0006699 ! bile acid biosynthetic process intersection_of: capable_of GO:0015721 ! bile acid and bile salt transport intersection_of: has_part UBERON:0001173 ! biliary tree disjoint_from: UBERON:0002330 ! exocrine system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0006699 ! bile acid biosynthetic process relationship: capable_of GO:0015721 ! bile acid and bile salt transport relationship: has_part UBERON:0001173 ! biliary tree relationship: part_of UBERON:0002423 ! hepatobiliary system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI property_value: RO:0002171 UBERON:0016478 [Term] id: UBERON:0002296 name: dorsal mesentery namespace: uberon def: "The mesentery that originates from the dorsal side of the peritoneal cavity[ZFA]." [Wikipedia:Dorsal_mesentery, Wikipedia:Mesentery#Development, ZFIN:curator] subset: uberon_slim subset: vertebrate_core synonym: "dorsal mesogastrium" RELATED [Wikipedia:Dorsal_mesentery] synonym: "mesenterium dorsale commune" RELATED LATIN [Wikipedia:Dorsal_mesentery] xref: EHDAA2:0004560 xref: EHDAA:3019 xref: EHDAA:3033 xref: EHDAA:3921 xref: EHDAA:3934 xref: EHDAA:3957 xref: EHDAA:3971 xref: FMA:79795 xref: SCTID:308823000 xref: TAO:0005130 xref: Wikipedia:Mesentery#Development xref: ZFA:0005130 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0002095 ! mesentery relationship: part_of UBERON:0009664 {source="EHDAA2"} ! gut mesentery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/85/Gray985.png" xsd:anyURI property_value: UBPROP:0000001 "The mesentery that originates from the dorsal side of the peritoneal cavity.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005130", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0002298 name: brainstem namespace: uberon def: "Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]." [ISBN:0471888893, MP:0005277, Wikipedia:Brainstem, ZFA:0001707] comment: 'brainstem' is a loose term that sometimes refers to the ventral parts o the brain except for any part of the telencephalon - sometimes it includes the diencephalon or subpallial telencephalon structures (ISBN:0471888893). Here we use it in a more restriced sense, to include only the medulla oblongata, pons (when present) and the midbrain tegmentum (following the ZFA definitions). subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "accessory medullary lamina of pallidum" RELATED [NeuroNames:236] synonym: "brain stem" EXACT [ABA:BS] synonym: "lamella pallidi incompleta" RELATED LATIN [NeuroNames:236] synonym: "lamina medullaris accessoria" RELATED LATIN [NeuroNames:236] synonym: "lamina medullaris incompleta pallidi" RELATED LATIN [NeuroNames:236] synonym: "lamina pallidi incompleta" RELATED LATIN [NeuroNames:236] synonym: "truncus encephali" EXACT LATIN [Wikipedia:Brainstem] synonym: "truncus encephalicus" RELATED LATIN [BTO:0000146] xref: BAMS:BS xref: BIRNLEX:1565 xref: BTO:0000146 xref: CALOHA:TS-0093 xref: EFO:0001962 xref: EMAPA:32678 xref: EV:0100241 xref: FMA:79876 xref: MA:0000169 xref: MBA:343 xref: MESH:D001933 xref: NCIT:C12441 xref: neuronames:236 {source="BIRNLEX:1565"} xref: SCTID:180925009 xref: TAO:0002156 xref: UMLS:C0006121 {source="BIRNLEX:1565", source="ncithesaurus:Brain_Stem"} xref: VHOG:0001457 xref: Wikipedia:Brainstem xref: ZFA:0001707 is_a: UBERON:0002616 ! regional part of brain relationship: continuous_with UBERON:0002240 ! spinal cord relationship: contributes_to_morphology_of UBERON:0000955 ! brain relationship: has_part UBERON:0001896 ! medulla oblongata relationship: has_part UBERON:0001943 ! midbrain tegmentum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray719.png" xsd:anyURI property_value: RO:0002171 UBERON:0001890 {notes="we apply a strict definition"} property_value: RO:0002171 UBERON:0002037 {exceptions="ZFA", source="ABA", source="https://github.com/obophenotype/uberon/issues/378", status="pending"} property_value: RO:0002171 UBERON:0002314 {notes="we apply a strict definition"} property_value: UBPROP:0000001 "Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002156", ontology="TAO", source="ISBN:3764351209"} property_value: UBPROP:0000001 "Multi-tissue structure that has as its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,adopted][ZFA:0001707]." xsd:string {source="ZFA:0001707"} property_value: UBPROP:0000001 "the stalk-like part of the brain that comprises the midbrain (aka mesencephalon), the pons (aka pons Varolii), and the medulla oblongata, and connects the cerebral hemispheres with the cervical spinal cord[MP]" xsd:string {source="MP:0005277"} [Term] id: UBERON:0002301 name: layer of neocortex namespace: uberon def: "One of the layers of the neocortex. These layers are defined by distinctive populations of cells based on somata size, shape, or density, that are aligned into sheets." [http://orcid.org/0000-0002-6601-2165, ISBN-10:0-87893-742-0, PMID:29081739] synonym: "cerebral cortex layer" RELATED [MA:0000186] synonym: "cortical layer" BROAD [] synonym: "lamina of neocortex" RELATED [FMA:83138] synonym: "layer of neocortex" EXACT [FMA:83138] synonym: "neocortex layer" EXACT [MA:0000186] xref: ABA:CTX1-6b xref: EMAPA:35588 xref: FMA:83138 xref: MA:0000186 is_a: UBERON:0022303 ! nervous system cell part layer is_a: UBERON:8440004 ! laminar subdivision of the cortex intersection_of: UBERON:0022303 ! nervous system cell part layer intersection_of: part_of UBERON:0001950 ! neocortex [Term] id: UBERON:0002302 name: myocardium of atrium namespace: uberon def: "The atrial part of middle layer of the heart, comprised of involuntary muscle." [ISBN:0-683-40008-8, MP:0010493] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "atrial myocardium" EXACT [ZFA:0001374] synonym: "atrium cardiac muscle" RELATED [VHOG:0000602] synonym: "atrium myocardium" EXACT [] xref: EFO:0003087 xref: EMAPA:32746 xref: FMA:83509 xref: MA:0000081 xref: SCTID:191910002 xref: TAO:0001374 xref: VHOG:0000602 xref: ZFA:0001374 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: contributes_to_morphology_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002081 ! cardiac atrium property_value: UBPROP:0000003 "As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000602", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002308 name: nucleus of brain namespace: uberon def: "A neural nucleus that is part of the brain." [http://orcid.org/0000-0002-6601-2165] synonym: "brain nuclei" RELATED PLURAL [ZFA:0005575] synonym: "brain nucleus" EXACT [] xref: EMAPA:35185 xref: FMA:83840 xref: MA:0000811 xref: NCIT:C49346 xref: SCTID:426465002 xref: UMLS:C1706993 {source="ncithesaurus:Brain_Nucleus"} xref: ZFA:0005575 is_a: UBERON:0000125 ! neural nucleus intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0003528 ! brain gray matter [Term] id: UBERON:0002315 name: gray matter of spinal cord namespace: uberon def: "The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue." [MP:0008503] subset: pheno_slim synonym: "gray matter of spinal cord" EXACT [OBOL:automatic] synonym: "gray substance of spinal cord" EXACT [FMA:256580] synonym: "grey matter of spinal cord" EXACT [] synonym: "grey substance of spinal cord" EXACT [] synonym: "spinal cord gray matter" EXACT [OBOL:automatic] synonym: "spinal cord grey matter" EXACT [] synonym: "spinal cord grey substance" EXACT [OBOL:automatic] synonym: "substantia grisea medullae spinalis" EXACT LATIN [FMA:256580, FMA:TA] xref: BAMS:Scgrey xref: DHBA:146035048 xref: EMAPA:35792 xref: FMA:256580 xref: MA:0000002 xref: NCIT:C32696 xref: neuronames:2619 xref: NLXANAT:100204 xref: SCTID:279441003 xref: UMLS:C0475853 {source="ncithesaurus:Gray_Matter_of_the_Spinal_Cord"} is_a: UBERON:0002020 ! gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0002240 ! spinal cord relationship: contributes_to_morphology_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0002316 name: white matter namespace: uberon def: "Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system." [https://orcid.org/0000-0002-6601-2165, Wikipedia:White_matter] subset: uberon_slim subset: vertebrate_core synonym: "CNS tract/commissure" EXACT [ZFA:0001682] synonym: "CNS tracts and commissures" RELATED [TAO:0000145] synonym: "CNS white matter" RELATED [TAO:0002143] synonym: "neuronal white matter" EXACT [AEO:0001011] synonym: "substantia alba" RELATED LATIN [Wikipedia:White_matter] synonym: "white mater" RELATED [VHOG:0001764] synonym: "white matter of neuraxis" EXACT [FMA:83929] synonym: "white substance" EXACT [] xref: AEO:0000139 xref: AEO:0001011 xref: EMAPA:35927 xref: FMA:83929 xref: HBA:9218 xref: MA:0001135 xref: MESH:D066127 xref: NCIT:C33892 xref: neuronames:2870 xref: NLX:412 xref: NLXANAT:101177 xref: PBA:294022044 xref: TAO:0000145 xref: TAO:0002142 xref: TAO:0002143 xref: UMLS:C0682708 {source="ncithesaurus:White_Matter"} xref: VHOG:0001764 xref: Wikipedia:White_matter xref: ZFA:0001682 is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: composed_primarily_of UBERON:0006135 ! myelinated nerve fiber property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d7/Grey_matter_and_white_matter_-_very_high_mag.jpg" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/d2/Spinal_nerve.svg" xsd:anyURI property_value: UBPROP:0000001 "Cell part cluster consisting predominantly of neurites in the brain and the spinal cord[FMA:83929]." xsd:string {source="FMA:83929"} property_value: UBPROP:0000001 "Multi-tissue structure comprised largely of myelinated axons.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002142", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The myelination of axons by glial cells was the last major step in the evolution of cells in the vertebrate nervous system, and white-matter tracts are key to the architecture of the mammalian brain.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001764", ontology="VHOG", source="DOI:10.1038/nature09614 Nave KA, Myelination and support of axonal integrity by glia. Nature (2010)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "nlx_anat_101177 seems to have been lost in the transition from NIFGA to Neurolex" xsd:string {external_ontology="NIF", seeAlso="https://github.com/SciCrunch/NIF-Ontology/issues/83"} [Term] id: UBERON:0002318 name: white matter of spinal cord namespace: uberon def: "The regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites." [MP:0008027] subset: pheno_slim synonym: "spinal cord white matter" EXACT [] synonym: "spinal cord white matter of neuraxis" EXACT [OBOL:automatic] synonym: "spinal cord white substance" EXACT [OBOL:automatic] synonym: "substantia alba medullae spinalis" EXACT LATIN [FMA:83945, FMA:TA] synonym: "white matter of neuraxis of spinal cord" EXACT [OBOL:automatic] synonym: "white substance of spinal cord" EXACT [OBOL:automatic] xref: BAMS:SCwhite xref: DHBA:146035088 xref: EMAPA:35795 xref: FMA:83945 xref: MA:0000910 xref: NCIT:C33893 xref: SCTID:279436006 xref: UMLS:C0458457 {source="ncithesaurus:White_Matter_of_the_Spinal_Cord"} is_a: UBERON:0002316 ! white matter intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0002240 ! spinal cord relationship: contributes_to_morphology_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0002323 name: coelemic cavity lumen namespace: uberon alt_id: UBERON:0000169 def: "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities." [BTO:0001707] subset: uberon_slim subset: vertebrate_core synonym: "body cavity" BROAD [BTO:0001707] synonym: "celom" RELATED [BTO:0001707] synonym: "coelom" RELATED [] synonym: "coelome" RELATED [BTO:0001707] synonym: "coelomic cavity" EXACT [EHDAA2:0000267] synonym: "coelomic cavity lumen" EXACT [EHDAA2:0000267] synonym: "hemocoel" RELATED [FBbt:00005060] synonym: "main body cavity" EXACT [] synonym: "space of body compartment" EXACT [FMA:85006] synonym: "ventral body cavity" NARROW [NCBITaxon:7742] xref: AEO:0000186 xref: BTO:0001707 xref: EHDAA2:0000267 xref: FBbt:00005060 xref: FMA:85006 xref: galen:BodyCavity xref: NCIT:C25444 xref: RETIRED_EHDAA2:0003186 xref: SCTID:361348008 xref: TAO:0001438 xref: UMLS:C0333343 {source="ncithesaurus:Cavity"} xref: ZFA:0001438 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity relationship: develops_from UBERON:0003886 ! future coelemic cavity lumen relationship: luminal_space_of UBERON:0011997 ! coelom relationship: part_of UBERON:0011997 ! coelom relationship: transformation_of UBERON:0003886 {evidence="definitional"} ! future coelemic cavity lumen property_value: editor_note "check the FMA placement here; ncit placement of body cavity here probably not correct" xsd:string property_value: UBPROP:0000001 "Anatomical space, part of the trunk that contains the pericardial and pleuroperitoneal cavities[ZFA]." xsd:string {date_retrieved="2012-09-12", external_class="ZFA:0001438", ontology="ZFA", source="ZFIN:curator"} property_value: UBPROP:0000001 "The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities[BTO]." xsd:string {date_retrieved="2012-09-12", external_class="BTO:0001707", ontology="BTO", source="BTO"} property_value: UBPROP:0000008 "In mammals it forms the peritoneal, pleural, and pericardial cavities" xsd:string [Term] id: UBERON:0002324 name: muscle of back namespace: uberon def: "Any muscle organ that is part of a back [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "back muscle" EXACT [] synonym: "back muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of back" EXACT [OBOL:automatic] xref: EMAPA:35161 xref: FMA:85216 xref: MA:0000496 is_a: UBERON:0001774 ! skeletal muscle of trunk is_a: UBERON:0005174 ! dorsal region element intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0004469 {source="prolog"} ! musculature of back property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002325 name: epithelium of urethra namespace: uberon def: "The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.." [GO:0061071] synonym: "epithelial tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra epithelial tissue" EXACT [OBOL:automatic] synonym: "urethra epithelium" EXACT [] synonym: "urethral epithelium" RELATED [] synonym: "urethral plate" RELATED [EMAPA:31518] synonym: "urethral seam" RELATED [EMAPA:31518] xref: EMAPA:31518 xref: FMA:85275 xref: MA:0001686 xref: NCIT:C49309 xref: UMLS:C1710584 {source="ncithesaurus:Urethra_Epithelium"} is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003914 {source="GO"} ! epithelial tube is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0006555 ! excretory tube is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0002326 name: lamina propria of urethra namespace: uberon def: "A lamina propria that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "lamina propria mucosa of urethra" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of urethra" EXACT [OBOL:automatic] synonym: "urethra lamina propria" EXACT [] synonym: "urethra lamina propria mucosa" EXACT [OBOL:automatic] synonym: "urethra lamina propria mucosae" EXACT [OBOL:automatic] synonym: "urethral lamina propria" RELATED [] xref: EMAPA:37785 {source="MA:th"} xref: FMA:85276 xref: MA:0001689 is_a: UBERON:0000030 ! lamina propria is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0002328 name: notochord namespace: uberon def: "A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube." [http://tolweb.org/Chordata/2499, https://github.com/obophenotype/uberon/issues/25, https://github.com/obophenotype/uberon/issues/271, ISBN:0815318960, Wikipedia:Notochord] comment: The notochord appears early in embryogeny and plays an important role in promoting or organizing the embryonic development of nearby structures. In most adult chordates the notochord disappears or becomes highly modified. In some non-vertebrate chordates and fishes the notochord persists as a laterally flexible but incompressible skeletal rod that prevents telescopic collapse of the body during swimming[TOLWEB] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "embryonic notocord" EXACT [] synonym: "notochorda" RELATED LATIN [Wikipedia:Notochord] synonym: "notocord" EXACT [ZFA:0000135] xref: AAO:0000327 xref: BTO:0001768 xref: CALOHA:TS-0690 xref: EHDAA2:0001277 xref: EHDAA:1241 xref: EHDAA:6021 xref: EMAPA:16191 xref: EV:0100002 xref: FMA:85521 xref: GAID:1311 xref: http://evolution.berkeley.edu/evolibrary/images/history/notochords.jpg xref: MAT:0000281 xref: MESH:D009672 xref: NCIT:C12463 xref: SCTID:308820002 xref: TAO:0000135 xref: UMLS:C0028439 {source="ncithesaurus:Notochord"} xref: VHOG:0000199 xref: VSAO:0000032 xref: Wikipedia:Notochord xref: XAO:0000055 xref: ZFA:0000135 is_a: UBERON:0000062 {source="PMID:15890825"} ! organ is_a: UBERON:0000481 {source="VSAO"} ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from UBERON:0004880 {source="ZFA"} ! chordamesoderm relationship: develops_from UBERON:0006267 {source="EHDAA2"} ! notochordal plate relationship: dorsal_to UBERON:0001555 ! digestive tract relationship: existence_starts_during UBERON:0000068 ! embryo stage relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000922 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! embryo relationship: part_of UBERON:0011137 ! axial skeletal system relationship: produces PR:000014841 ! sonic hedgehog protein relationship: ventral_to UBERON:0001049 ! neural tube property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: UBPROP:0000001 "Avascular multi-tissue structure composed of large vacuolated epithelial cells (chordablasts) and perichordal fibrous tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000032", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Rod-like principal supportive element of the embryo and larva, present in the midline just ventral to the neural tube, and differentiating during the segmentation period to form large vacuolated epithelial cells and a surrounding a sheath of fibrous and elastic layers. Layering of the sheath may differ in structure, thickness and development among groups; in cypriniforms there are actually three very thin layers to the sheath. A functional, well developed notochord is present throughout life in certain basal fish groups but not in cypriniforms. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000135", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Slender rod of fibrous connective tissue surrounding a core of fluid-filled cells of mesodermal origin; it lies above the gut and directly beneath the spinal cord. The notochord is present during early development and in a few cases it is retained through life; however, usually the notochord is replaced by the vertebral column.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000327", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship type change: differentiates_from mesoderm (AAO:0000304) CHANGED TO: develops_from mesoderm (UBERON:0000926)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000327", ontology="AAO"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (3) a stiff, longitudinal rod of turgid cells along the dorsal part of the body that is called a notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000199", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "notochordal" xsd:string property_value: UBPROP:0000011 "In between vertebra the notochord becomes the nucleus pulposus, under it degenerates, and at anterior end in some species its tissue merges with some of the cranial bones.. Some organisms retain a post-embryonic notochord." xsd:string [Term] id: UBERON:0002329 name: somite namespace: uberon def: "Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm." [DOI:10.1111/j.1439-0426.2012.01987.x, Wikipedia:Somite] comment: When the somite becomes segmented from the segmental plate, it is composed of an epithelial sac enclosing mesenchymal somitocoel cells. Thereafter the somite differentiates into two parts, the ventro-medial mesenchymal sclerotome and the dorso-lateral epithelial dermomyotome. This change in the epithelial somite depends on surrounding tissue [PMID:15906248] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "epimere" RELATED [ISBN:0073040584] synonym: "epimere mesoderm" RELATED [] synonym: "epithelial somite" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "mesodermal cluster" BROAD [GO:0001756] synonym: "somites" RELATED PLURAL [] synonym: "somitic mesoderm" RELATED [] synonym: "somitus" RELATED LATIN [Wikipedia:Somite] xref: AAO:0010569 xref: AEO:0001015 xref: BTO:0001558 xref: EHDAA2:0003436 xref: EHDAA:366 xref: EHDAA:699 xref: EMAPA:31169 xref: FMA:85522 xref: GAID:1306 xref: MAT:0000068 xref: MESH:D019170 xref: MIAA:0000068 xref: NCIT:C34302 xref: TAO:0000155 xref: UMLS:C0376449 {source="ncithesaurus:Somite"} xref: VHOG:0000191 xref: Wikipedia:Somite xref: XAO:0000058 xref: ZFA:0000155 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle relationship: develops_from UBERON:0003059 {source="ZFA"} ! presomitic mesoderm relationship: only_in_taxon NCBITaxon:7711 {source="GOTAX:0000352"} ! Chordata property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: editor_note "currently classified as an epithelial vesicle, consistent with EHDAA2 and https://github.com/obophenotype/uberon/wiki/The-neural-crest. Consider making 'somitic mesoderm' a separate term and correlate with regionalization processes. Consider moving ZFA term to 'trunk somite' as it is part of the trunk" xsd:string property_value: RO:0002161 NCBITaxon:7712 {source="PMID:17237766"} property_value: UBPROP:0000001 "Post-cranial axial segments which form sclerotome and dermomyotome.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010569", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Undifferentiated mesodermal components of early trunk or tail segments or metameres, derived from paraxial mesoderm; forms myotomes, sclerotomes and perhaps dermatomes. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000155", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from paraxial mesenchyme (TAO:0000942)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000155", ontology="TAO"} property_value: UBPROP:0000002 "relationship type change: OBO_REL:part_of trunk (TAO:0001115) CHANGED TO: develops_from trunk (UBERON:0002100)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000155", ontology="TAO"} property_value: UBPROP:0000002 "relationship type change: part_of paraxial mesoderm (AAO:0010568) CHANGED TO: develops_from paraxial mesoderm (UBERON:0003077)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010569", ontology="AAO"} property_value: UBPROP:0000003 "(...) cephalocordates and craniates belong to a group known as Somitichordata. Somitichordate synapomorphies include (1) somites (...) (reference 1); The idea that the last common ancestor of bilaterian animals (Urbilateria) was segmented has been raised recently on evidence coming from comparative molecular embryology (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000191", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.40, DOI:10.1093/icb/43.1.137 Balavoine G, Adoutte A, The segmented urbilateria: a testable scenario. Integrative and Comparative Biology (2003)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "somitic" xsd:string [Term] id: UBERON:0002330 name: exocrine system namespace: uberon def: "Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]." [Wikipedia:Exocrine_gland] subset: pheno_slim subset: uberon_slim synonym: "exocrine glandular system" EXACT [EHDAA2:0002225] xref: CALOHA:TS-2057 xref: EHDAA2:0002225 xref: EMAPA:35329 xref: FMA:85539 xref: MA:0002411 xref: NCIT:C12957 xref: UMLS:C1516995 {source="ncithesaurus:Exocrine_System"} xref: Wikipedia:Exocrine_gland xref: WikipediaCategory:Exocrine_system is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0002390 ! hematopoietic system disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: composed_primarily_of UBERON:0002365 ! exocrine gland relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa [Term] id: UBERON:0002331 name: umbilical cord namespace: uberon def: "The connecting cord from the developing embryo to the placenta." [ISBN:0-683-40008-8, MP:0001725, PMID:9144284, Wikipedia:Umbilical_cord] comment: See notes for connecting stalk subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "birth cord" RELATED [Wikipedia:Umbilical_cord] synonym: "chorda umbilicalis" EXACT LATIN [MP:0012134] synonym: "connecting stalk" RELATED [] synonym: "funiculus umbilicalis" EXACT LATIN [MP:0012134] synonym: "funiculus umbilicalis" RELATED LATIN [Wikipedia:Umbilical_cord] synonym: "yolk stalk" RELATED [BTO:0001415] xref: BTO:0001415 xref: CALOHA:TS-1078 xref: EFO:0001415 xref: EHDAA2:0000312 xref: EHDAA:158 xref: EMAPA:26115 xref: EV:0100127 xref: FMA:85541 xref: GAID:517 xref: MAT:0000280 xref: MESH:D014470 xref: MIAA:0000280 xref: NCIT:C34320 xref: SCTID:280644003 xref: UMLS:C0041633 {source="ncithesaurus:Umbilical_Cord"} xref: Wikipedia:Umbilical_cord is_a: UBERON:0000478 ! extraembryonic structure relationship: connects UBERON:0000922 ! embryo relationship: connects UBERON:0001987 ! placenta relationship: develops_from UBERON:0007806 ! connecting stalk property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f3/Umbilicalcord.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The connecting cord from the developing embryo or fetus to the placenta. During prenatal development, the umbilical cord comes from the same zygote as the fetus and (in humans) normally contains two arteries (the umbilical arteries) and one vein (the umbilical vein), buried within Wharton's jelly. The umbilical vein supplies the fetus with oxygenated, nutrient-rich blood from the placenta.property_value, external_definition the umbilical arteries return the deoxygenated, nutrient-depleted blood[WP]." xsd:string {source="Wikipedia:Umbilical_cord"} property_value: UBPROP:0000007 "umbilical" xsd:string [Term] id: UBERON:0002333 name: pulmonary trunk namespace: uberon def: "An arterial trunk which is continuous with the heart and branches into the pulmonary arteries." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "main pulmonary artery" RELATED [Wikipedia:Pulmonary_artery] synonym: "pulmonary artery (trunk)" EXACT [] synonym: "trunk of pulmonary arterial tree" EXACT [] xref: EHDAA2:0001576 xref: EHDAA:9831 xref: EMAPA:17015 xref: FMA:8612 xref: galen:PulmonaryTrunk xref: MA:0002033 xref: NCIT:C116918 xref: VHOG:0001134 is_a: UBERON:0001637 {source="MA"} ! artery relationship: connected_to UBERON:0002080 ! heart right ventricle relationship: continuous_with UBERON:0000948 ! heart relationship: continuous_with UBERON:0002080 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! heart right ventricle relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0008886 ! pulmonary vascular system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/db/Alveoli_diagram.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "An arterial trunk with origin from the right ventricle of the heart, and dividing into the right and left pulmonary arteries, which enter the corresponding lungs and branch with the bronchi. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001134", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/pulmonary+trunk"} property_value: UBPROP:0000003 "As in birds, the conus arteriosus split during embryonic development in mammals to produce the pulmonary trunk and single aortic trunk of the adult.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001134", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.481", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002337 name: endometrial stroma namespace: uberon def: "The layer of connective tissue comprised of the endometrial lining of the uterus which fluctuates in thickness throughout the menstrual cycle." [ncithesaurus:Endometrial_Stroma] subset: human_reference_atlas synonym: "endometrium stroma" EXACT [] synonym: "stroma of endometrium" EXACT [] xref: CALOHA:TS-1266 xref: EMAPA:35310 xref: FMA:86487 xref: MA:0002734 xref: NCIT:C32516 xref: SCTID:254115004 xref: UMLS:C0227849 {source="ncithesaurus:Endometrial_Stroma"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003891 ! stroma is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0001295 ! endometrium relationship: part_of UBERON:0001295 ! endometrium property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002338 name: lamina propria of bronchus namespace: uberon def: "A lamina propria that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi lamina propria" EXACT [OBOL:automatic] synonym: "bronchi lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bronchi lamina propria mucosae" EXACT [OBOL:automatic] synonym: "bronchial lamina propria" RELATED [EMAPA:35194] synonym: "bronchial trunk lamina propria" EXACT [OBOL:automatic] synonym: "bronchial trunk lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bronchial trunk lamina propria mucosae" EXACT [OBOL:automatic] synonym: "bronchus lamina propria" EXACT [] synonym: "bronchus lamina propria mucosa" EXACT [OBOL:automatic] synonym: "bronchus lamina propria mucosae" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bronchi" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bronchial trunk" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of bronchus" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bronchi" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bronchial trunk" EXACT [OBOL:automatic] synonym: "lamina propria mucosae of bronchus" EXACT [OBOL:automatic] synonym: "lamina propria of bronchi" EXACT [OBOL:automatic] synonym: "lamina propria of bronchial trunk" EXACT [OBOL:automatic] xref: EMAPA:35194 xref: FMA:86619 xref: MA:0001836 xref: NCIT:C49212 xref: UMLS:C1707054 {source="ncithesaurus:Bronchus_Lamina_Propria"} is_a: UBERON:0000031 ! lamina propria of trachea is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0000410 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! bronchial mucosa [Term] id: UBERON:0002342 name: neural crest namespace: uberon def: "A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]." [MP:0009846] comment: Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995), slug (Nieto et al., 1994), AP-2 (Zhang et al., 1996; Schorle et al., 1996), and Wnt-1/3a (Ikeya et al., 1997) are expressed in the dorsal most region of the neural tube, and have been shown to be involved in the generation of neural crest cells. subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "crista neuralis" RELATED LATIN [Wikipedia:Neural_crest] synonym: "NC" EXACT ABBREVIATION [XAO:0000048] synonym: "neural crest material" RELATED [VHOG:0000057] xref: AAO:0010578 xref: BTO:0001764 xref: CALOHA:TS-0676 xref: EHDAA2:0004419 xref: EMAPA:32737 xref: FMA:86666 xref: GAID:1310 xref: MAT:0000066 xref: MESH:D009432 xref: MIAA:0000066 xref: NCIT:C34222 xref: neuronames:1366 xref: SCTID:361462002 xref: TAO:0000045 xref: UMLS:C0027789 {source="ncithesaurus:Neural_Crest"} xref: VHOG:0000057 xref: Wikipedia:Neural_crest xref: XAO:0000048 xref: ZFA:0000045 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest is_a: UBERON:0010316 ! germ layer / neural crest relationship: composed_primarily_of CL:0000333 {notes="pre migratory https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! migratory neural crest cell relationship: develops_from UBERON:0003075 {source="BTO"} ! neural plate relationship: develops_from UBERON:0005062 {source="PMID:11523831"} ! neural fold relationship: existence_starts_during UBERON:0000110 {source="PMID:11523831"} ! neurula stage relationship: only_in_taxon NCBITaxon:89593 {notes="Hall and others restrict NC to vertebrates but we opt for a less restrictive constraint to avoid inconsistencies when areas such as P1 area of pallium in hagfishes inherit cell lineage from telecephalon-contributing NC cells", source="ISBN:0073040584"} ! Craniata relationship: part_of UBERON:0002346 {source="XAO", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! neurectoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray644.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png" xsd:anyURI property_value: editor_note "consider including subclasses for pre- and post- migratory (e.g. sheets/paths/streams)." xsd:string property_value: RO:0002174 NCBITaxon:117565 {source="ISBN:0073040584", source="PMID:17377535"} property_value: UBPROP:0000001 "A cell population arising from the dorsolateral aspect of the central nervous system primordium during the segmentation period, and later migrating along stereotyped pathways to give rise to a diverse and well-defined set of cell types including pigment cells, peripheral neurons and glia, and head cartilage. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000045", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Migratory cell population which delaminates from neural tube, borders surface ectoderm and neural ectoderm, and gives rise to many different tissue types.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010578", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "A well developed neural crest population is present in lampreys (Horigome et al. 1999 ; Tomsa & Langeland, 1999) and gnathostomes. chordate fossils from the early Cambrian (Yunnanozoan and Haikouella) with apparent neural-crest derived structures (pharyngeal denticles and pharyngeal skeletons resembling the striped mucocartilage of the branchial bars in lamprey ammocoete larvae), suggests that neural crest arose very early in vertebrate evolution (Chen et al. 1999; Holland & Chen, 2001). The invertebrate chordates apparently lack defini- tive neural crest. One marker of migrating neural crest in some vertebrates, the antibody HNK1, does not recognize any cells in amphioxus embryos (Holland, unpublished). Even so, in both amphioxus and tunicates, cells at the edges of the neural plate and adjacent nonneural ectoderm share some properties of neural crest[PMID:11523831]" xsd:string {source="PMID:11523831"} property_value: UBPROP:0000003 "We conclude that the neural crest is a vertebrate novelty, but that neural crest cells and their derivatives evolved and diversified in a step-wise fashion - first by elaboration of neural plate border cells, then by the innovation or co-option of new or ancient metazoan cell fates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000057", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2012.01495.x Hall BK, Gillis JA, Incremental evolution of the neural crest, neural crest cells and neural crest-derived skeletal tissues. J Anat (2012)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002343 name: abdomen musculature namespace: uberon def: "Set of all muscles in abdomen." [OBOL:automatic] subset: pheno_slim subset: vertebrate_core synonym: "abdominal musculature" EXACT [] synonym: "muscle group of abdomen" EXACT [FMA:71294] synonym: "muscles of abdomen" EXACT [FMA:71294] synonym: "musculature of abdomen" EXACT [] synonym: "musculature of abdominal wall" EXACT [FMA:86917] synonym: "set of muscles of abdomen" EXACT [FMA:71294] xref: FMA:71294 xref: FMA:86917 xref: TAO:0001327 xref: ZFA:0001327 is_a: UBERON:0004479 ! musculature of trunk intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen property_value: IAO:0000232 "distinction between abdomen muscle and abdomen musculature" xsd:string [Term] id: UBERON:0002345 name: descending thoracic aorta namespace: uberon def: "The part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest." [MP:0009868] subset: efo_slim subset: human_reference_atlas subset: pheno_slim xref: EFO:0002527 xref: EMAPA:18605 xref: FMA:87217 xref: MA:0002572 xref: SCTID:181301002 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0013522 ! subdivision of tube relationship: contributes_to_morphology_of UBERON:0001514 ! descending aorta relationship: contributes_to_morphology_of UBERON:0001515 ! thoracic aorta relationship: part_of UBERON:0001514 ! descending aorta relationship: part_of UBERON:0001515 ! thoracic aorta property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002346 name: neurectoderm namespace: uberon def: "Embryonic ectoderm that gives rise to nervous tissue." [Wikipedia:Neuroectoderm] subset: uberon_slim subset: vertebrate_core synonym: "epithelium tubi neuralis; neuroectoderma" RELATED LATIN [Wikipedia:Neuroectoderm] synonym: "neuaral ectoderm" RELATED [] synonym: "neural ectoderm" EXACT [] synonym: "neuroectoderm" EXACT [] synonym: "presumptive central nervous system" RELATED [] synonym: "ventral neurogenic region" RELATED [VHOG:0000150] xref: AAO:0011074 xref: BILA:0000039 xref: CALOHA:TS-1212 xref: EHDAA2:0001248 xref: EHDAA:1498 xref: EHDAA:255 xref: EMAPA:16073 xref: EV:0100004 xref: FBbt:00001057 xref: FMA:87657 xref: MAT:0000176 xref: MIAA:0000176 xref: NCIT:C34228 xref: TAO:0001120 xref: UMLS:C1518271 {source="ncithesaurus:Neuroectoderm"} xref: VHOG:0000150 xref: Wikipedia:Neuroectoderm xref: XAO:0000042 xref: ZFA:0001120 is_a: UBERON:0000923 ! germ layer is_a: UBERON:0004121 ! ectoderm-derived structure relationship: has_part CL:0000133 ! neurectodermal cell relationship: has_part CL:0000530 {source="ZFA"} ! primary neuron property_value: UBPROP:0000003 "(...) the ability of ectoderm to produce neuronal cells is a general metazoan feature.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000150", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "neurectodermal" xsd:string property_value: UBPROP:0000013 "we prefer neurectoderm to neural ectoderm since placodal ectoderm is not classified here" xsd:string [Term] id: UBERON:0002347 name: thoracic vertebra namespace: uberon def: "A thoracic vertebra endochondral element that is composed primarily of a bone tissue." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "dorsal vertebra" EXACT [] synonym: "thorax vertebra" EXACT [OBOL:automatic] synonym: "vertebra of thorax" EXACT [OBOL:automatic] synonym: "vertebra thoracica" EXACT [] xref: EMAPA:18011 xref: FMA:9139 xref: GAID:244 xref: MA:0000314 xref: MESH:D013904 xref: NCIT:C12798 xref: SCTID:181821009 xref: UMLS:C0039987 {source="ncithesaurus:Thoracic_Vertebra"} xref: Wikipedia:Thoracic_vertebrae is_a: UBERON:0002412 ! vertebra is_a: UBERON:0003827 ! thoracic segment bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0015008 ! thoracic vertebra endochondral element intersection_of: UBERON:0015008 ! thoracic vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0013507 ! thoracic vertebra cartilage element property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray90.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "Thoracic vertebrae in all species are defined as those vertebrae which also carry a pair of ribs, and lie caudal to the cervical vertebrae. In humans, they are distinguished by the presence of facets on the sides of the bodies for articulation with the heads of the ribs, and facets on the transverse processes of all, except the eleventh and twelfth, for articulation with the tubercles of the ribs" xsd:string [Term] id: UBERON:0002348 name: epicardium namespace: uberon def: "A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "heart epicardium" EXACT [] synonym: "pericardium visceral mesothelium" RELATED [EMAPA:16589] synonym: "visceral serous pericardium of heart" EXACT [FMA:9461] synonym: "visceral serous pericardium proper" EXACT [FMA:9461] xref: AAO:0010409 xref: EHDAA2:0002202 xref: FMA:9461 xref: galen:Epicardium xref: NCIT:C13164 xref: TAO:0005057 xref: UMLS:C0225968 {source="ncithesaurus:Epicardium"} xref: VHOG:0000119 xref: Wikipedia:Epicardium xref: XAO:0000316 xref: ZFA:0005057 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure relationship: attaches_to UBERON:0002349 {source="FMA"} ! myocardium relationship: develops_from UBERON:0004160 ! proepicardium relationship: part_of UBERON:0000948 {source="multiple"} ! heart relationship: part_of UBERON:0002425 {source="FMA-inferred"} ! visceral serous pericardium property_value: editor_note "TODO - check links with UBERON:0002425 visceral serous pericardium. develops from proepicardium. WP:Epicardium -- When considered as a part of the pericardium, it is the inner layer, or visceral pericardium, continuous with the serous layer." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "External layer of the heart.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005057", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The inner layer of the pericardium that is in contact with the surface of the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010409", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000009 "The visceral pericardium apparently produces the pericardial fluid, which lubricates motion between the inner and outer layers of the pericardium. During ventricular contraction, the wave of depolarization moves from endocardial to epicardial surface. [Wikipedia:Epicardium]" xsd:string [Term] id: UBERON:0002349 name: myocardium namespace: uberon def: "The middle layer of the heart, comprised mainly of striated cardiac muscle fibers." [ISBN:0-683-40008-8, MP:0005329] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cardiac muscle" RELATED [ZFA:0001319] synonym: "heart muscle" RELATED [FMA:9462, ZFA:0001319] synonym: "heart myocardium" EXACT [] synonym: "muscle of heart" EXACT [FMA:9462] xref: AAO:0010410 xref: BSA:0000089 xref: BTO:0000901 xref: CALOHA:TS-0440 xref: EFO:0000819 xref: EHDAA2:0004150 xref: EMAPA:32688 xref: EV:0100022 xref: FMA:9462 xref: GAID:173 xref: galen:Myocardium xref: MA:0000164 xref: MAT:0000453 xref: MESH:D009206 xref: NCIT:C12371 xref: RETIRED_EHDAA2:0001220 xref: SCTID:362012001 xref: TAO:0001319 xref: UMLS:C0027061 {source="ncithesaurus:Myocardium"} xref: VHOG:0000083 xref: Wikipedia:Myocardium xref: XAO:0000065 xref: ZFA:0001319 is_a: UBERON:0005983 ! heart layer is_a: UBERON:0018260 ! layer of muscle tissue intersection_of: UBERON:0005983 ! heart layer intersection_of: composed_primarily_of UBERON:0001133 ! cardiac muscle tissue relationship: composed_primarily_of UBERON:0001133 ! cardiac muscle tissue relationship: has_part UBERON:0002350 ! conducting system of heart relationship: part_of UBERON:0000383 ! musculature of body property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6e/Glanzstreifen.jpg" xsd:anyURI property_value: editor_note "TODO - check 'Myocardum proper' in FMA. We superclass the more generic class for now. FMA has is_a muscle layer - should we add this? ZFA and BTO both have is_a 'cardiac muscle' (tissue?). But in U we also follow FMA and have cardiac muscle tissue of myocardium (there is also Fibrocollagenous connective tissue of myocardium), which would be identical (see issue-10). Note that GO also treats left/right ventricular cardiac muscle tissue synonymous with ventricular myocardium" xsd:string property_value: UBPROP:0000001 "Robust muscular tunic of the heart which forms the basic part of its walls. Its external surface is covered by the pericardium and its internal one by the endocardium. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000083", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "The middle layer of the heart, consisting of cardiac muscle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010410", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000007 "myocardial" xsd:string [Term] id: UBERON:0002350 name: conducting system of heart namespace: uberon def: "The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]." [GO:0003161] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "cardiac conducting system" EXACT [VHOG:0001271] synonym: "cardiac conduction system" EXACT [] synonym: "cardiac impulse conducting system" EXACT [GO:0003161] synonym: "cardionector" EXACT [] synonym: "central conduction system" RELATED [] synonym: "complexus stimulans cordis" EXACT LATIN [FMA:9476, FMA:TA] synonym: "heart conduction system" EXACT [GO:0003161] synonym: "impulse conducting system" EXACT [MA:0000094] synonym: "systema conducente cordis" EXACT LATIN [FMA:9476, FMA:TA] xref: EFO:0003909 xref: EHDAA2:0004185 xref: EMAPA:35428 xref: EV:0100025 xref: FMA:9476 xref: MA:0000094 xref: MESH:D006329 xref: SCTID:281489000 xref: TAO:0005063 xref: VHOG:0001271 xref: ZFA:0005063 is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart relationship: contributes_to_morphology_of UBERON:0000948 ! heart relationship: has_part CL:0002068 {source="FMA"} ! Purkinje myocyte relationship: has_part CL:0002073 {source="FMA"} ! transitional myocyte relationship: has_part CL:0002074 {source="FMA"} ! myocardial endocrine cell relationship: has_part CL:1000409 {source="FMA"} ! myocyte of sinoatrial node relationship: has_part CL:1000410 {source="FMA"} ! myocyte of atrioventricular node property_value: editor_note "EHDAA2 divides the system from the tissue" xsd:string property_value: UBPROP:0000003 "The fish heart displays clear polarity of contraction in a posterior-to-anterior direction. The contraction waves originate in the sinus venosus and terminate in the conus arteriosus. The nodal phenotype persists in the inflow region of the heart, varying from the venosinus to the sinoatrial junctional areas in different species . Similar to the mammalian situation, pacemaker tissue with a lower intrinsic rhythmicity is also found at the atrioventricular junction.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001271", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM, Christoffels VM, Cardiac Chamber Formation: Development, Genes, and Evolution. Physiological Reviews (2003)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002351 name: sinoatrial node namespace: uberon def: "The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]." [GO:0003163, Wikipedia:Sinoatrial_node] comment: WP:Heart states: "The SA node is found in all amniotes but not in more primitive vertebrates. In these animals, the muscles of the heart are relatively continuous and the sinus venosus coordinates the beat which passes in a wave through the remaining chambers. Indeed, since the sinus venosus is incorporated into the right atrium in amniotes, it is likely homologous with the SA node. In teleosts, with their vestigial sinus venosus, the main centre of coordination is, instead, in the atrium.". Note however that ZFA has SA node. subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cardiac pacemaker" EXACT [FMA:9477] synonym: "Koch's node" EXACT [FMA:9477] synonym: "node of Keith-Flack" EXACT [FMA:9477] synonym: "nodus sinuatrialis" EXACT LATIN [FMA:9477, FMA:TA] synonym: "nodus sinuatrialis" RELATED LATIN [Wikipedia:Sinoatrial_node] synonym: "SA nodal muscle tissue" EXACT [FMA:9477] synonym: "SA node" EXACT [FMA:9477] synonym: "sinoatrial node" EXACT [FMA:9477] synonym: "sinu-atrial node" EXACT [FMA:9477] synonym: "sinuatrial nodal muscle tissue" EXACT [FMA:9477] synonym: "sinuatrial node" EXACT [FMA:9477] synonym: "sinus node" EXACT [FMA:9477] synonym: "sinus node of Keith and Flack" EXACT [FMA:9477] xref: BTO:0004358 xref: EHDAA2:0004184 xref: EMAPA:35772 xref: FMA:9477 xref: GAID:561 xref: MA:0000097 xref: MESH:D012849 xref: NCIT:C33555 xref: SCTID:277687007 xref: TAO:0005069 xref: UMLS:C0037189 {source="ncithesaurus:Sinoatrial_Node"} xref: Wikipedia:Sinoatrial_node xref: ZFA:0005069 is_a: UBERON:0003379 ! cardiac muscle of right atrium is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart relationship: capable_of GO:0002027 ! regulation of heart rate relationship: capable_of_part_of GO:0060048 ! cardiac muscle contraction relationship: contributes_to_morphology_of UBERON:0002350 ! conducting system of heart relationship: in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0002350 {source="ZFA"} ! conducting system of heart property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d2/Sinoatrial_node_low_mag.jpg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/de/Sinoatrial_node_2_low_mag.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002352 name: atrioventricular node namespace: uberon def: "An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles." [UBERON:cjm, Wikipedia:Atrioventricular_node] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "A-V node" RELATED [EMAPA:35153] synonym: "Aschoff-Tawara node" EXACT [FMA:9478] synonym: "atrio-ventricular node" RELATED [EMAPA:35153] synonym: "atrioventricular nodal muscle tissue" EXACT [FMA:9478] synonym: "atriovetricular node" RELATED [TAO:0005070] synonym: "AV nodal muscle tissue" EXACT [FMA:9478] synonym: "AV node" EXACT [FMA:9478, MA:0000095] synonym: "downstream pacemaker" RELATED [ZFA:0005070] synonym: "node of Tawara" EXACT [FMA:9478] synonym: "nodus atrioventricularis" EXACT LATIN [FMA:TA] synonym: "nodus atrioventricularis" RELATED LATIN [Wikipedia:Atrioventricular_node] xref: BTO:0005689 xref: EFO:0000276 xref: EHDAA2:0004183 xref: EMAPA:35153 xref: FMA:9478 xref: GAID:558 xref: MA:0000095 xref: MAT:0000498 xref: MESH:D001283 xref: NCIT:C32161 xref: SCTID:277688002 xref: TAO:0005070 xref: UMLS:C0004247 {source="ncithesaurus:Atrioventricular_Node"} xref: VHOG:0001474 xref: Wikipedia:Atrioventricular_node xref: ZFA:0005070 is_a: UBERON:0004491 ! cardiac muscle tissue of interatrial septum is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart relationship: connected_to UBERON:0002085 ! interatrial septum relationship: connected_to UBERON:0005979 ! crista terminalis relationship: contributes_to_morphology_of UBERON:0002350 ! conducting system of heart relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002350 ! conducting system of heart property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/ConductionsystemoftheheartwithouttheHeart.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/92/Gray501.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "Three major adaptations, or 'novel cardiac components', that were not present in the ancestor chordate heart tube can be distinguished in the lower vertebrate heart: the atrium, ventricle, and possibly the muscular sinus venosus. Furthermore, within the ventricular component a compact outer myocardial component and an interiorly localized extensive trabecular component can be distinguished. The specific activation of the ventricle adds to its complexity as follows. The depolarizing impulse travels rapidly from the atrioventricular node toward the apex and then toward the conal region, achieving activation from apex to base.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001474", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM, Christoffels VM, Cardiac Chamber Formation: Development, Genes, and Evolution. Physiological Reviews (2003)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002354 name: cardiac Purkinje fiber namespace: uberon alt_id: UBERON:0004147 def: "The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." [GO:0003165] subset: pheno_slim subset: uberon_slim synonym: "cardiac Purkinje fiber" EXACT [BTO:0001735, GO:0003165] synonym: "heart Purkinje fiber" RELATED [BTO:0001735] synonym: "myofibra conducens cardiacus" EXACT LATIN [] synonym: "Purkinje fiber" EXACT [FMA:9492, MA:0000096] synonym: "subendocardial branch" EXACT [Wikipedia:Purkinje_fiber] xref: BTO:0001735 xref: EMAPA:35718 xref: FMA:9492 xref: GAID:560 xref: MA:0000096 xref: MESH:D011690 xref: NCIT:C33430 xref: UMLS:C0034144 {source="ncithesaurus:Purkinje_Fiber"} xref: Wikipedia:Purkinje_fiber is_a: UBERON:0010131 {source="FMA"} ! conducting tissue of heart is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: contributes_to_morphology_of UBERON:0002350 ! conducting system of heart relationship: has_part CL:0002068 {source="FMA"} ! Purkinje myocyte relationship: part_of UBERON:8000009 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! Purkinje fiber network property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray498.png" xsd:anyURI [Term] id: UBERON:0002355 name: pelvic region of trunk namespace: uberon def: "The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/720, Wikipedia:Pelvis] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "lesser pelvis" EXACT [FMA:9578] synonym: "pelvic region" EXACT [] synonym: "pelvis" EXACT [FMA:9578, MA:0000030] synonym: "pelvis region" EXACT [] synonym: "true pelvis" EXACT [FMA:9578] xref: BTO:0001006 xref: CALOHA:TS-2227 xref: EFO:0002805 xref: EMAPA:35931 xref: EV:0100012 xref: FMA:9578 xref: GAID:87 xref: galen:Pelvis xref: MA:0000030 xref: MESH:D010388 xref: NCIT:C12767 xref: SCTID:229765004 xref: UMLS:C0030797 {source="ncithesaurus:Pelvis"} xref: Wikipedia:Pelvis is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000475 ! organism subdivision relationship: has_part UBERON:0007832 ! pelvic girdle skeleton relationship: part_of UBERON:0002417 ! abdominal segment of trunk property_value: UBPROP:0000007 "pelvic" xsd:string property_value: UBPROP:0000012 "MA and FMA differ in what they consider to be parts of the pelvis. MA includes ureter, urethra, urinary bladder, reproductive organs" xsd:string {external_ontology="MA"} [Term] id: UBERON:0002357 name: serous pericardium namespace: uberon def: "Serous membrane which is divided into parietal and visceral serous pericardium." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Serous_pericardium] subset: uberon_slim synonym: "pericardium serosum" RELATED LATIN [Wikipedia:Serous_pericardium] synonym: "serous portion of pericardium" EXACT [FMA:9582] xref: EMAPA:19030 xref: FMA:9582 xref: MA:0002739 xref: SCTID:243954002 xref: Wikipedia:Serous_pericardium is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000042 ! serous membrane relationship: attaches_to UBERON:0002359 {source="FMA"} ! fibrous pericardium relationship: has_part UBERON:0002408 ! parietal serous pericardium relationship: has_part UBERON:0002425 ! visceral serous pericardium relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002406 {source="FMA"} ! pericardial sac [Term] id: UBERON:0002358 name: peritoneum namespace: uberon def: "A serous membrane that lines the peritoneal cavity[VHOG,modified]." [VHOG:0001257] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "peritonaeum" RELATED [VHOG:0001257] xref: AAO:0010814 xref: BTO:0001472 xref: CALOHA:TS-2072 xref: EV:0100087 xref: FMA:9584 xref: GAID:18 xref: galen:Peritoneum xref: MA:0000449 xref: MESH:D010537 xref: NCIT:C12770 xref: TAO:0005120 xref: UMLS:C0031153 {source="ncithesaurus:Peritoneum"} xref: VHOG:0001257 xref: Wikipedia:Peritoneum xref: XAO:0000139 xref: ZFA:0005120 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0035820 ! peritoneal sac relationship: part_of UBERON:0003697 {source="MP"} ! abdominal wall relationship: part_of UBERON:0035820 ! peritoneal sac property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray1040.png" xsd:anyURI property_value: editor_note "TODO - in ZFA is_a epithelium" xsd:string property_value: UBPROP:0000001 "An epithelium that lines the peritoneal cavity.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005120", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Serous membrane that forms the lining of the abdominal cavity or the coelom. It covers most of the intra-abdominal organs, supports the abdominal organs, and serves as a conduit for their blood and lymph vessels and nerves. It is composed of a layer of mesothelium.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010814", ontology="AAO", source="AAO:JMG"} property_value: UBPROP:0000007 "peritoneal" xsd:string property_value: UBPROP:0000012 "todo: check MA/EMAPA." xsd:string {external_ontology="MA"} [Term] id: UBERON:0002359 name: fibrous pericardium namespace: uberon def: "Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]." [FMA:9586] subset: organ_slim subset: uberon_slim synonym: "fibrous portion of pericardium" EXACT [] synonym: "pericardium fibrosum" RELATED LATIN [Wikipedia:Fibrous_pericardium] xref: EMAPA:19029 xref: FMA:9586 xref: MA:0002738 xref: SCTID:243953008 xref: Wikipedia:Fibrous_pericardium is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000094 {source="FMA"} ! membrane organ is_a: UBERON:0005181 ! thoracic segment organ relationship: composed_primarily_of UBERON:0006815 {source="WP"} ! areolar connective tissue relationship: continuous_with UBERON:0002408 ! parietal serous pericardium relationship: part_of UBERON:0002407 {source="FMA"} ! pericardium property_value: UBPROP:0000010 "most superficial part of pericardium; continuous with the outer adventitial layer of the neighboring great blood vessels. [Wikipedia:Pericardium]" xsd:string [Term] id: UBERON:0002360 name: meninx namespace: uberon def: "Membrane organ that surrounds the brain and the spinal cord." [FMA:9589, http://www.shsu.edu/~bio_mlt/Chap15.html, Wikipedia:Meninx] subset: efo_slim subset: organ_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "layer of meninges" EXACT [] synonym: "meningeal layer" EXACT [] synonym: "meninx primitiva" NARROW [VHOG:0001295] xref: BTO:0000144 xref: CALOHA:TS-1177 xref: EFO:0000867 xref: EMAPA:32660 xref: EV:0100312 xref: FMA:9589 xref: GAID:687 xref: MA:0001113 xref: MAT:0000113 xref: MESH:D008578 xref: NCIT:C12348 xref: NLXANAT:090204 xref: TAO:0001355 xref: UMLS:C0025285 {source="ncithesaurus:Meninges"} xref: VHOG:0001295 xref: Wikipedia:Meninx xref: ZFA:0001355 is_a: UBERON:0000094 {source="FMA"} ! membrane organ is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from UBERON:0007645 ! future meninx relationship: immediate_transformation_of UBERON:0007645 {source="Bgee:AN"} ! future meninx relationship: part_of UBERON:0010743 ! meningeal cluster property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/48/Illu_meninges.jpg" xsd:anyURI property_value: UBPROP:0000001 "Membrane covering the brain and spinal cord. It is represented by a single layer in fishes, two in amphibians, reptiles and birds and three in mammals (named dura mater, arachnoid and pia mater). [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001295", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/meninges"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001295", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "meningeal" xsd:string property_value: UBPROP:0000008 "Whereas cyclostomes and fishes only have a single envelope called the primitive meninx, amphibians have two layers, consisting of an outer dura mater which is extremely dense and protective, and a pia-arachnoid or secondary meninx which is more delicate and vascular. Mammals have three meninges: pia mater (which follows all the convolutions of the brain and is the most interior), the arachnoid layer (which is delicate and sends strands to the pia mater), and the dura mater (the outer, more protective meninx)." xsd:string property_value: UBPROP:0000012 "Not consider part of the CNS/neuraxis in FMA" xsd:string {external_ontology="FMA", seeAlso="https://github.com/obophenotype/uberon/issues/1261"} property_value: UBPROP:0000202 FMA:76821 [Term] id: UBERON:0002363 name: dura mater namespace: uberon def: "Thick, fibrous meningeal covering surrounding the brain and spinal cord. It is the outermost of the three meningeal coverings. It consists of two layers: the periosteal dura linking the inner surface of the skull and the meningeal dura that lies above the arachnoid dural membrane. The meningeal layer draws away from the periosteal layer and certain locations to form the dural reflections." [NLXANAT:090206] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "dura" RELATED [BTO:0001637] synonym: "dura mater of neuraxis" EXACT [] synonym: "pachymeninges" EXACT [NLXANAT:090206] xref: BTO:0001637 xref: CALOHA:TS-2008 xref: EMAPA:32664 xref: EV:0100313 xref: FMA:9592 xref: GAID:691 xref: MA:0001115 xref: MESH:D004388 xref: NCIT:C32488 xref: neuronames:1462 xref: NLXANAT:090206 xref: SCTID:362301008 xref: UMLS:C0013313 {source="ncithesaurus:Dura_Mater"} xref: Wikipedia:Dura_mater is_a: UBERON:0002360 ! meninx relationship: continuous_with UBERON:0001773 {source="PMID:16496288"} ! sclera relationship: develops_from UBERON:0007647 ! ectomeninx relationship: immediate_transformation_of UBERON:0007647 {evidence="definitional"} ! ectomeninx property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8e/Meninges-en.svg" xsd:anyURI property_value: RO:0002161 NCBITaxon:32443 {source="ISBN:0073040584"} property_value: UBPROP:0000001 "the outermost of the three layers of the meninges surrounding the brain and spinal cord. The other two meningeal layers are the pia mater and the arachnoid mater. The dura surrounds the brain and the spinal cord and is responsible for keeping in the cerebrospinal fluid[Wikipedia:Dura_mater]." xsd:string {source="Wikipedia:Dura_mater"} property_value: UBPROP:0000009 "capable of inducing chondrogenesis - requires contact with an epithelium - http://www.ncbi.nlm.nih.gov/pubmed/16496288" xsd:string property_value: UBPROP:0000012 "some ontologies consider dura mater part of the CNS, others dispute this and claim it surrounds it (e.g. DOI:10.1111/joa.12381)[https://github.com/obophenotype/uberon/issues/1261]" xsd:string [Term] id: UBERON:0002364 name: tympanic membrane namespace: uberon def: "A thin membrane that separates the external ear from the middle ear, consisting of two epithelia (one part of the the external accoustic meatus epithelium, the other part of the tympanic cavity epithelium) with a fibrous layer between them. Its function is to transmit sound from the air to the ossicles inside the middle ear. The malleus bone bridges the gap between the eardrum and the other ossicles. Rupture or perforation of the eardrum can lead to conductive hearing loss. [WP,unvetted]." [PMID:11237469, Wikipedia:Tympanic_membrane] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "ear drum" EXACT [] synonym: "eardrum" EXACT [] synonym: "lateral wall of tympanic cavity" EXACT [] synonym: "membranous wall of tympanic cavity" EXACT [] synonym: "myrinx" EXACT [] synonym: "paries membranaceus cavi tympani" EXACT LATIN [FMA:9595, FMA:TA] synonym: "Rivinus' membrane" EXACT [] synonym: "tympanum" RELATED [Wikipedia:Tympanic_membrane] xref: EMAPA:19062 xref: FMA:9595 xref: GAID:870 xref: MA:0000257 xref: MESH:D014432 xref: NCIT:C12502 xref: SCTID:181180005 xref: UMLS:C0041445 {source="ncithesaurus:Tympanic_Membrane"} xref: VHOG:0001146 xref: Wikipedia:Tympanic_membrane xref: XAO:0000212 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000094 {source="FMA"} ! membrane organ relationship: adjacent_to UBERON:0004114 {source="cjm"} ! tympanic cavity relationship: contributes_to_morphology_of UBERON:0001756 ! middle ear relationship: develops_from UBERON:0009213 {source="Wikipedia"} ! pharyngeal membrane of 1st arch relationship: has_part UBERON:0005042 ! inner epithelial layer of tympanic membrane relationship: has_part UBERON:0010069 ! outer epithelial layer of tympanic membrane relationship: has_part UBERON:0010070 ! intermediate layer of tympanic membrane relationship: overlaps UBERON:0001352 ! external acoustic meatus relationship: overlaps UBERON:0001691 {source="cjm"} ! external ear relationship: part_of UBERON:0001756 {source="MA"} ! middle ear property_value: RO:0002161 NCBITaxon:8459 {source="Wikipedia"} property_value: UBPROP:0000001 "The thin membrane which closes externally the cavity of the middle ear and is deeply sited at the bottom of the external auditory meatus. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001146", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In particular, a tympanic membrane was not present in the earliest tetrapods (...). An ear utilizing a tympanic membrane evolved independently at least three times in tetrapods: (1) in the lineage that leads to anurans (frogs), (2) in the line of evolution to turtles and diapsids, and (3) in the late synapsid lineage that gave rise to mammals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001146", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.418", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "The tympanic membrane (TM) has three layers, two epithelia provided by the external acoustic meatus (EAM) and the MEC, derived respectively from the first pharyngeal cleft and pouch, and a mesenchymally derived fibrous stratum" xsd:string property_value: UBPROP:0000012 "most AOs consider this part of the middle ear, so we go with this and place it in the middle ear as a border to the external, although it could be considered to overlap the external ear in that it has an EAM layer as part - for this reason we do not consider middle and external ear to be spatially disjoint." xsd:string {source="PMID:11237469"} [Term] id: UBERON:0002365 name: exocrine gland namespace: uberon def: "A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas." [Wikipedia:Exocrine_gland] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "ducted gland" EXACT [AEO:0000097] synonym: "glandula exocrina" EXACT LATIN [Wikipedia:Exocrine_gland] xref: AEO:0000097 xref: BTO:0000765 xref: CALOHA:TS-2012 xref: EHDAA2:0003097 xref: EMAPA:35327 xref: FMA:9596 xref: GAID:34 xref: MA:0002564 xref: MESH:D005088 xref: NCIT:C12712 xref: SCTID:115976003 xref: UMLS:C0015282 {source="ncithesaurus:Exocrine_Gland"} xref: Wikipedia:Exocrine_gland is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002330 ! exocrine system relationship: has_part UBERON:0000058 ! duct relationship: part_of UBERON:0002330 ! exocrine system property_value: editor_note "Currently this is logically defined by the system it belongs to, but a better system may be base this on presence/absence of ducts. However, the dual nature of the liver should be taken into consideration here. Consider adding subclasses" xsd:string [Term] id: UBERON:0002368 name: endocrine gland namespace: uberon def: "Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]." [Wikipedia:Endocrine_gland] subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "ductless gland" EXACT [AEO:0000098] synonym: "ductless gland" RELATED [Wikipedia:Ductless_gland] synonym: "glandula endocrina" EXACT [] synonym: "glandulae endocrinae" RELATED LATIN [Wikipedia:Endocrine_gland] xref: AEO:0000098 xref: BTO:0001488 xref: CALOHA:TS-1300 xref: EHDAA2:0003098 xref: EMAPA:35999 xref: FMA:9602 xref: GAID:335 xref: MA:0002563 xref: MESH:D004702 xref: NCIT:C12704 xref: SCTID:40818001 xref: UMLS:C0014133 {source="ncithesaurus:Endocrine_Gland"} xref: Wikipedia:Endocrine_gland is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000949 ! endocrine system relationship: capable_of GO:0046879 ! hormone secretion relationship: part_of UBERON:0000949 ! endocrine system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/da/Illu_endocrine_system.png" xsd:anyURI [Term] id: UBERON:0002371 name: bone marrow namespace: uberon def: "The soft tissue that fills the cavities of bones." [MGI:cwg, MP:0002397] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "medulla of bone" RELATED [BTO:0000141] synonym: "medulla ossea" EXACT LATIN [BTO:0000141, FMA:9608] synonym: "medulla ossium" EXACT LATIN [BTO:0000141, Wikipedia:Bone_marrow] synonym: "medullary bone" RELATED [] xref: AAO:0011007 xref: BTO:0000141 xref: BTO:0000829 xref: CALOHA:TS-0087 xref: EFO:0000868 xref: EMAPA:32760 xref: EV:0100046 xref: FMA:9608 xref: GAID:1287 xref: galen:BoneMarrow xref: MA:0000134 xref: MAT:0000084 xref: MESH:D001853 xref: MIAA:0000084 xref: NCIT:C12431 xref: SCTID:421320006 xref: UMLS:C0005953 {source="ncithesaurus:Bone_Marrow"} xref: VHOG:0001218 xref: Wikipedia:Bone_marrow xref: XAO:0000123 is_a: UBERON:0000479 ! tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000479 ! tissue intersection_of: has_part UBERON:0012429 ! hematopoietic tissue intersection_of: part_of UBERON:0001474 ! bone element relationship: has_part CL:0002092 ! bone marrow cell relationship: has_part UBERON:0012429 ! hematopoietic tissue relationship: part_of UBERON:0001474 ! bone element relationship: part_of UBERON:0002390 {source="FMA", source="MA"} ! hematopoietic system relationship: part_of UBERON:0002405 ! immune system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/74/Gray72-en.svg" xsd:anyURI property_value: editor_note "consider placement of NCIT:C53466 medullary bone" xsd:string property_value: editor_note "TODO - create superclass for bone marrow / head kidney. both are portions of tissue in the hematopoetic system. also consider adding as subclass of zone of bone organ for consistency with FMA. See also: Leydig and epigonal organs" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "The bone marrow is the hematopoietic organ in all vertebrates but fishes, in which hematopoiesis occurs in the kidney.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001218", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V, Blood Cells and Blood Cell Development in the Animal Kingdom. Annual Review of Cell and Developmental Biology (2006)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000009 "In adults, marrow in large bones produces new blood cells[Wikipedia:Bone_marrow]" xsd:string [Term] id: UBERON:0002374 name: metacarpal bone namespace: uberon def: "A bone that is part of the metacarpal skeleton." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Metacarpal_bone] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "metacarpal" EXACT [] xref: EFO:0003886 xref: EMAPA:36158 xref: FMA:9612 xref: galen:Metacarpal xref: MA:0000302 xref: NCIT:C12751 xref: SCTID:181977005 xref: SCTID:425761003 xref: UMLS:C0025526 {source="ncithesaurus:Metacarpal_Bone"} xref: Wikipedia:Metacarpal_bone is_a: UBERON:0003607 ! forelimb long bone is_a: UBERON:0003821 {is_inferred="true"} ! metapodium bone is_a: UBERON:0012358 ! manual digitopodium bone is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0004453 ! metacarpus region relationship: connected_to UBERON:0001435 ! carpal bone relationship: connected_to UBERON:0001436 ! phalanx of manus relationship: part_of UBERON:0010544 ! metacarpus skeleton property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/2/2f/Metacarpals_numbered-en.svg" xsd:anyURI [Term] id: UBERON:0002376 name: cranial muscle namespace: uberon alt_id: UBERON:0003899 def: "Any skeletal muscle that is part of the head region." [http://orcid.org/0000-0002-6601-2165] comment: defined generically so could in theory encompass FBbt:00003260 'skeletal muscle of head', or the muscle of a starfish Aristotle's lantern, but we restrict this to craniates. Skeletal muscles of the head originate from the non-segmented head mesoderm (Noden, 1983; Wachtler et al., 1984) subset: efo_slim subset: human_reference_atlas subset: uberon_slim subset: vertebrate_core synonym: "adult head muscle organ" NARROW [OBOL:automatic] synonym: "cephalic muscle" EXACT [ZFA:0001652] synonym: "cephalic musculature" EXACT [] synonym: "cranial muscle" RELATED [ZFA:0001652] synonym: "head muscle" EXACT [MA:0000578] synonym: "head muscle organ" EXACT [OBOL:automatic] synonym: "head muscles" RELATED [] synonym: "muscle of head" EXACT [FMA:9616] synonym: "muscle organ of adult head" EXACT [OBOL:automatic] synonym: "muscle organ of head" EXACT [OBOL:automatic] synonym: "musculus caput" EXACT [] xref: AAO:0000107 xref: BTO:0000021 xref: EFO:0003524 xref: EHDAA2:0000322 xref: EMAPA:18172 xref: FMA:9616 xref: MA:0000578 xref: SCTID:244718003 xref: ZFA:0001652 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010959 ! craniocervical muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0003129 ! skull intersection_of: part_of UBERON:0000033 ! head relationship: attaches_to UBERON:0003129 ! skull relationship: develops_from UBERON:0006904 {source="EHDAA2-abduced"} ! head mesenchyme from mesoderm relationship: has_developmental_contribution_from UBERON:0002342 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! neural crest relationship: part_of UBERON:0004461 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! skeletal musculature of head property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002377 name: muscle of neck namespace: uberon def: "Any muscle that is part of the cervical (neck) region." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "muscle organ of neck" EXACT [OBOL:automatic] synonym: "muscle organ of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) muscle organ" EXACT [OBOL:automatic] synonym: "neck muscle" EXACT [] synonym: "neck muscle organ" EXACT [OBOL:automatic] xref: EMAPA:36050 xref: FMA:9617 xref: GAID:149 xref: MA:0000587 xref: MESH:D009334 xref: NCIT:C33163 xref: UMLS:C0027532 {source="ncithesaurus:Neck_Muscle"} is_a: UBERON:0010959 ! craniocervical muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0004465 {source="prolog"} ! musculature of neck property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002378 name: muscle of abdomen namespace: uberon def: "Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis." [Wikipedia:Abdominal_muscle] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "abdomen muscle" EXACT [] synonym: "abdomen muscle organ" EXACT [OBOL:automatic] synonym: "abdominal muscle" EXACT [] synonym: "abdominal wall muscle" EXACT [] synonym: "abdominal wall musculature" RELATED [EMAPA:35103] synonym: "muscle organ of abdomen" EXACT [OBOL:automatic] xref: BTO:0001261 xref: EMAPA:35103 xref: FMA:9620 xref: GAID:89 xref: MA:0000520 xref: MESH:D000009 xref: NCIT:C32040 xref: SCTID:361352008 xref: UMLS:C0000739 {source="ncithesaurus:Abdominal_Muscle"} xref: Wikipedia:Abdominal_muscle is_a: UBERON:0003833 ! abdominal segment muscle is_a: UBERON:0005172 ! abdomen element intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0002343 {source="prolog"} ! abdomen musculature relationship: part_of UBERON:0003697 ! abdominal wall property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002380 name: trapezius muscle namespace: uberon def: "A large superficial muscle that extends longitudinally from the occipital bone to the lower thoracic vertebrae and laterally to the spine of the scapula (shoulder blade). Its functions are to move the scapulae and support the arm. The trapezius has three functional regions: the superior region (descending part), which supports the weight of the arm; the intermediate region (transverse part), which retracts the scapulae; and the inferior region (ascending part), which medially rotates and depresses the scapulae. [WP,unvetted]." [Wikipedia:Trapezius_muscle] subset: human_reference_atlas subset: uberon_slim synonym: "musculus trapezius" RELATED LATIN [Wikipedia:Trapezius_muscle] synonym: "spinotrapezius" RELATED [Wikipedia:Trapezius_muscle] synonym: "trapezius" EXACT [] xref: EMAPA:18183 xref: FMA:9626 xref: MA:0002398 xref: NCIT:C33809 xref: SCTID:181740005 xref: UMLS:C0224361 {source="ncithesaurus:Trapezius_Muscle"} xref: VHOG:0000834 xref: Wikipedia:Trapezius_muscle is_a: UBERON:0001482 ! muscle of shoulder is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from UBERON:0010955 ! trapezius pre-muscle mass relationship: has_muscle_antagonist UBERON:0001112 {source="dbpedia"} ! latissimus dorsi muscle relationship: has_muscle_antagonist UBERON:0001125 {source="dbpedia"} ! serratus ventralis relationship: has_muscle_insertion UBERON:0002497 {notes="posterior border of the lateral third of the clavicle acromion process and spine of scapula", source="dbpedia"} ! acromion relationship: has_muscle_insertion UBERON:0007173 {notes="posterior border of the lateral third of the clavicle acromion process and spine of scapula", source="dbpedia"} ! lateral border of scapula relationship: has_muscle_origin UBERON:0000351 {notes="external occipital protuberance nuchal ligament medial superior nuchal line spinous processes of vertebrae C7-T12", source="dbpedia"} ! nuchal ligament relationship: has_muscle_origin UBERON:0001076 {notes="external occipital protuberance nuchal ligament medial superior nuchal line spinous processes of vertebrae C7-T12", source="dbpedia"} ! neural spine property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/60/Trapezius.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "The sternomastoid and the three parts of the trapezius are branchiomeric muscles that have secondarily acquired an attachment to the pectoral girdle. They evolved from the fish cucullaris.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000834", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.345", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002384 name: connective tissue namespace: uberon def: "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/23, PSPUB:0000170, VSAO:0000017] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "Bindegewebe" RELATED [BTO:0000421] synonym: "portion of connective tissue" EXACT [FMA:9640] synonym: "textus connectivus" EXACT [] xref: AAO:0000098 xref: BTO:0000421 xref: CALOHA:TS-2009 xref: EFO:0000952 xref: EMAPA:35251 xref: FMA:9640 xref: GAID:100 xref: galen:ConnectiveTissue xref: MA:0000011 xref: MAT:0000301 xref: MESH:D003238 xref: MIAA:0000301 xref: NCIT:C12374 xref: SCTID:361919005 xref: TAO:0001641 xref: UMLS:C0009780 {source="ncithesaurus:Connective_Tissue"} xref: VSAO:0000017 xref: XAO:0001017 xref: ZFA:0001632 is_a: UBERON:0000479 ! tissue relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of the four types of tissue in traditional classifications. It is largely a category of exclusion rather than one with a precise definition, but there are certain characteristics shared by all or most tissues in this category, such as involvement in structure and support, derived from mesoderm, and characterized largely by the traits of non-living tissue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000098", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "Portion of tissue that consists of mesodermally derived cells and intercellular matrix comprised of protein fibers and carbohydrates, which supports, ensheathes and binds together other tissues.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001641", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000017", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} property_value: UBPROP:0000012 "MA also has set of connective tissues" xsd:string {external_ontology="MA"} [Term] id: UBERON:0002385 name: muscle tissue namespace: uberon def: "Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]." [GO:0060537, https://sourceforge.net/tracker/index.php?func=detail&aid=2801266&group_id=36855&atid=440764, Wikipedia:Muscle_tissue] comment: Vertebrate muscle is categorized into three major muscle types defined by their structural and functional properties: skeletal, cardiac and smooth. In Dmel the counterparts are somatic, heart/cardiac and visceral. Here we take a cell type based approach. subset: uberon_slim synonym: "muscular tissue" EXACT SENSU [] synonym: "portion of muscle tissue" EXACT [FMA:9641] synonym: "textus muscularis" EXACT [] xref: AAO:0000306 xref: AEO:0000122 xref: CALOHA:TS-0642 xref: EHDAA2:0003122 xref: EMAPA:32715 xref: FMA:9641 xref: galen:MuscleTissue xref: MA:0002437 xref: MESH:D009132 xref: NCIT:C12435 xref: SCTID:91727004 xref: UMLS:C2328219 {source="ncithesaurus:Muscle_Tissue"} xref: Wikipedia:Muscle_tissue is_a: UBERON:0000479 ! tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000479 ! tissue intersection_of: composed_primarily_of CL:0000187 ! muscle cell disjoint_from: UBERON:0003714 ! neural tissue relationship: capable_of GO:0006936 ! muscle contraction relationship: composed_primarily_of CL:0000187 ! muscle cell relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001015 ! musculature property_value: RO:0002171 UBERON:0003714 property_value: UBPROP:0000001 "One of the four types of tissue in traditional classifications. Tissue that contains cells with contractile filaments that move past each other and change the size of the cell. Muscle tissue also is separated into three distinct categories.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000306", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0002386 name: forelimb zeugopod namespace: uberon def: "The middle limb segment of the pectoral free limb, between the autopod and stylopod segments. Includes as parts the forelimb zeugopodial skeleton, which includes as parts the radius and ulna, or their cartilage precursors, or evolutionary variants." [PHENOSCAPE:curators] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "antebrachial region" EXACT [] synonym: "antebrachium" EXACT [VSAO:0005058, Wikipedia:Forearm] synonym: "antebrachium" RELATED LATIN [Wikipedia:Forearm] synonym: "antibrachium" EXACT [] synonym: "arm middle limb segment" EXACT [OBOL:automatic] synonym: "arm zeugopod" EXACT [OBOL:automatic] synonym: "brachial region middle limb segment" EXACT [OBOL:automatic] synonym: "brachial region zeugopod" EXACT [OBOL:automatic] synonym: "fore epipodium" RELATED [] synonym: "forearm" EXACT [] synonym: "forelimb epipodium" EXACT [] synonym: "forelimb zeugopodium" EXACT [] synonym: "forelimb zygopod" EXACT [] synonym: "intermediate segment of free upper limb" EXACT [] synonym: "lower arm" EXACT HUMAN_PREFERRED [MA:0000034] synonym: "lower segment of arm" EXACT [] synonym: "middle limb segment of arm" EXACT [OBOL:automatic] synonym: "middle limb segment of brachial region" EXACT [OBOL:automatic] synonym: "middle limb segment of forelimb" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "middle limb segment of proximal segment of free upper limb" EXACT [OBOL:automatic] synonym: "regio antebrachialis" EXACT LATIN [FMA:9663, FMA:TA] synonym: "wing zeugopod" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "zeugopod of arm" EXACT [] synonym: "zeugopod of brachial region" EXACT [OBOL:automatic] synonym: "zeugopod of forelimb" EXACT [] synonym: "zeugopod of proximal segment of free upper limb" EXACT [OBOL:automatic] xref: BTO:0001447 xref: CALOHA:TS-2205 xref: EFO:0003053 xref: EHDAA2:0000553 xref: EHDAA:4172 xref: EHDAA:6218 xref: EMAPA:17417 xref: FMA:9663 xref: GAID:55 xref: galen:Forearm xref: MA:0000034 xref: MESH:D005542 xref: NCIT:C32628 xref: SCTID:362741001 xref: UMLS:C0016536 {source="ncithesaurus:Forearm"} xref: VHOG:0000341 xref: VSAO:0005058 xref: Wikipedia:Forearm is_a: UBERON:0002471 ! zeugopod is_a: UBERON:0008785 ! upper limb segment intersection_of: UBERON:0002471 ! zeugopod intersection_of: part_of UBERON:0002102 ! forelimb relationship: has_skeleton UBERON:0010703 ! forelimb zeugopod skeleton relationship: part_of UBERON:0001460 {source="MA"} ! arm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3b/Veins.jpg" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/50/Forearm_labeled.png" xsd:anyURI property_value: UBPROP:0000001 "The middle forelimb region. [Evolution, Fourth_Edition_(2006)_Boston_etc.:_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.321, see_Kardong_KV][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000341", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000341", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group. TODO - add distinct term for skeleton and place AAO class here" xsd:string [Term] id: UBERON:0002387 name: pes namespace: uberon def: "Distal portion of the hind limb, including tarsal region, metatarsal region and digits." [Wikipedia:Foot, Wikipedia:Pes_(anatomy)] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "foot" EXACT HUMAN_PREFERRED [MA:0000044] synonym: "hind foot" NARROW [] synonym: "hind limb autopodium" RELATED [VHOG:0000350] synonym: "hind paw" NARROW SENSU [EMAPA:17428, OBOL:automatic] synonym: "hind-paw" NARROW SENSU [EMAPA:17428] synonym: "hindfeet" NARROW PLURAL [] synonym: "hindfoot" NARROW [] synonym: "hindfoot of quadruped" NARROW [] synonym: "hindlimb autopod" EXACT [OBOL:automatic] synonym: "hindlimb autopodium" EXACT [OBOL:automatic] synonym: "hindlimb distal free limb segment" EXACT [OBOL:automatic] synonym: "hindpaw" NARROW SENSU [MA:0000044] synonym: "pes" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "terminal segment of free lower limb" EXACT [] xref: BTO:0000476 xref: CALOHA:TS-0377 xref: EFO:0003065 xref: EHDAA2:0000546 xref: EMAPA:17459 xref: FMA:9664 xref: GAID:40 xref: galen:Foot xref: MA:0000044 xref: MESH:D005528 xref: NCIT:C32622 xref: SCTID:302545001 xref: UMLS:C0016504 {source="ncithesaurus:Foot"} xref: VHOG:0000350 xref: Wikipedia:Pes_(anatomy) is_a: UBERON:0002470 ! autopod region is_a: UBERON:0008784 ! lower limb segment intersection_of: UBERON:0002470 ! autopod region intersection_of: part_of UBERON:0002103 ! hindlimb relationship: develops_from UBERON:0006871 ! embryonic footplate relationship: has_skeleton UBERON:0001445 ! skeleton of pes property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ae/Male_Right_Foot_1.jpg" xsd:anyURI property_value: UBPROP:0000007 "pedal" xsd:string [Term] id: UBERON:0002389 name: manual digit namespace: uberon alt_id: UBERON:0000028 def: "A digit that is part of a manus (hand)." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "digit of hand" EXACT [FMA:9666] synonym: "digit of manus" EXACT [] synonym: "digitus manus" EXACT [] synonym: "finger" EXACT [FMA:9666] synonym: "fore digit" EXACT [AAO:0000857, XAO:0003036] synonym: "forelimb digit" EXACT [] synonym: "hand digit" EXACT [MA:0000041] synonym: "manual digit (phalangeal portion) plus soft tissue" EXACT COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000857 xref: BTO:0004669 xref: EHDAA2:0000404 xref: EMAPA:32642 xref: FMA:9666 xref: GAID:57 xref: galen:Finger xref: MA:0000041 xref: MESH:D005385 xref: NCIT:C32608 xref: NLXANAT:20090602 xref: SCTID:283992002 xref: UMLS:C0016129 {source="ncithesaurus:Finger"} xref: Wikipedia:Finger xref: XAO:0003036 is_a: UBERON:0002544 ! digit intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0012141 {source="PHENOSCAPE:ni"} ! manual digitopodium region relationship: part_of UBERON:5002389 ! manual digit plus metapodial segment property_value: UBPROP:0000001 "One of the fingers of the manus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000857", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0002390 name: hematopoietic system namespace: uberon def: "Anatomical system that is involved in the production of hematopoietic cells." [Wikipedia:Haematopoiesis] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "Blutbildungssystem" RELATED [BTO:0000570] synonym: "haematological system" EXACT [] synonym: "haematopoietic system" RELATED [] synonym: "haemopoietic system" EXACT [] synonym: "hematological system" RELATED [] synonym: "hematolymphoid system" RELATED [] synonym: "hemopoietic system" RELATED [] synonym: "organa haemopoietica" EXACT [] xref: AAO:0011002 xref: BTO:0000570 xref: CALOHA:TS-0449 xref: EFO:0000798 xref: EMAPA:35402 xref: EV:0100045 xref: FMA:9667 xref: GAID:1008 xref: MA:0002434 xref: MAT:0000022 xref: MESH:D006413 xref: MIAA:0000022 xref: NCIT:C12909 xref: SCTID:362587009 xref: TAO:0005023 xref: UMLS:C0018957 {source="ncithesaurus:Hematopoietic_System"} xref: VHOG:0001624 xref: Wikipedia:Haematopoiesis xref: XAO:0000122 xref: ZFA:0005023 is_a: UBERON:0000467 ! anatomical system is_a: UBERON:0004120 ! mesoderm-derived structure disjoint_from: UBERON:0002405 ! immune system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: develops_from UBERON:0003061 {evidence="definitional"} ! blood island relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0002193 {source="FMA"} ! hemolymphoid system property_value: UBPROP:0000001 "Anatomical system that consists of the blood and blood forming tissues.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011002", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "Zebrafish developmental hematopoiesis shows close correspondence to the development of the mammalian hematopoietic system and is regulated by conserved molecular pathways.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001624", ontology="VHOG", source="DOI:10.1016/j.coph.2010.05.004 Ellett F, Lieschke GJ, Zebrafish as a model for vertebrate hematopoiesis. Current Opinion in Pharmacology (2010)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "hematopoietic" xsd:string property_value: UBPROP:0000008 "In humans this is primarily the bone marrow, spleen, tonsils, and lymph nodes" xsd:string {source="WP"} [Term] id: UBERON:0002394 name: bile duct namespace: uberon def: "Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Bile_duct] subset: pheno_slim subset: uberon_slim synonym: "bile tube" RELATED [] synonym: "biliary duct" RELATED [FMA:9706] synonym: "gall duct" RELATED [BTO:0000122] synonym: "hepatic duct" RELATED INCONSISTENT [ZFA:0001100] xref: AAO:0011019 xref: BTO:0000122 xref: CALOHA:TS-0075 xref: EHDAA2:0000741 xref: EMAPA:35171 xref: EV:0100091 xref: FMA:9706 xref: GAID:280 xref: MA:0000354 xref: MESH:D001652 xref: NCIT:C12376 xref: SCTID:276157007 xref: TAO:0001100 xref: UMLS:C0005400 {source="ncithesaurus:Bile_Duct"} xref: VHOG:0000212 xref: Wikipedia:Bile_duct xref: XAO:0000134 xref: ZFA:0001100 is_a: UBERON:0000025 ! tube is_a: UBERON:0003928 ! digestive system duct is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001173 ! biliary tree relationship: channel_for UBERON:0001970 ! bile relationship: contributes_to_morphology_of UBERON:0001173 ! biliary tree relationship: develops_from UBERON:0008835 {source="XAO"} ! hepatic diverticulum relationship: part_of UBERON:0001173 {source="EMAPA", source="MA"} ! biliary tree property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5d/Digestive_system_showing_bile_duct.png" xsd:anyURI property_value: UBPROP:0000001 "A duct that carries bile from the liver to the intestine." xsd:string {source="ZFA:0001100, ZFA:curator"} property_value: UBPROP:0000001 "Any of the excretory ducts in the liver that convey bile between the liver and the intestine. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000212", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/bile+duct"} property_value: UBPROP:0000003 "(...) the amphibian liver has characteristics in common with both fish and terrestrial vertebrates. (...) The histological structure of the liver is similar to that in other vertebrates, with hepatocytes arranged in clusters and cords separated by a meshwork of sinusoids and the presence of the traditional triad of portal venule, hepatic arteriole, and bile duct.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000212", ontology="VHOG", source="DOI:10.1053/ax.2000.7133 Crawshaw GJ, Weinkle TK, Clinical and pathological aspects of the amphibian liver. Seminars in Avian and Exotic Pet Medicine (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "we place the ZFA class here as this fits its textual definition and child nodes. We may recommend a label change for ZFA" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0002395 name: talus namespace: uberon def: "A proximal tarsal bone resulting from fusion of intermedium and fibulare." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Talus_bone] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "astragaloid bone" RELATED [BTO:0002354] synonym: "astragalus" RELATED [ISBN:0073040584, MA:000135, Wikipedia:Talus_bone] synonym: "astragalus bone" RELATED [ISBN:0073040584, Wikipedia:Talus_bone] synonym: "major ankle bone" RELATED [] synonym: "os tarsi tibiale" RELATED [BTO:0002354] synonym: "os trigonum" RELATED [Wikipedia:Talus_bone] xref: BTO:0002354 xref: EMAPA:19135 xref: FMA:9708 xref: GAID:196 xref: galen:Talus xref: MA:0001351 xref: MESH:D013628 xref: NCIT:C52799 xref: SCTID:182098005 xref: UMLS:C0039277 {source="ncithesaurus:Talus"} xref: Wikipedia:Talus_bone is_a: UBERON:0011679 ! proximal tarsal bone intersection_of: UBERON:0011679 ! proximal tarsal bone intersection_of: derived_from_ancestral_fusion_of UBERON:0011678 ! hindlimb intermedium bone intersection_of: derived_from_ancestral_fusion_of UBERON:0012126 ! fibulare relationship: connected_to UBERON:0000979 ! tibia relationship: derived_from_ancestral_fusion_of UBERON:0011678 ! hindlimb intermedium bone relationship: derived_from_ancestral_fusion_of UBERON:0012126 ! fibulare property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/a/a9/Subtalar_Joint.PNG" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "The talus is apparently derived from the fusion of three separate bones in the feet of primitive amphibians; the tibiale, articulating with tibia, the intermedium, between the bases of the tibia and fibula, and the fourth centrale, lying in the mid-part of the tarsus. These bones are still partially separate in modern amphibians, which therefore do not have a true talus. The talus forms a considerably more flexible joint in mammals than it does in reptiles. This reaches its greatest extent in artiodactyls, where the distal surface of the bone has a smooth keel to allow greater freedom of movement of the foot, and thus increase running speed" xsd:string {source="WP"} [Term] id: UBERON:0002396 name: vomer namespace: uberon def: "The triangular flat bone of the nasal septum." [ISBN:0-683-40008-8, MP:0000098] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "prevomer" RELATED [TAO:0000308] synonym: "vomer bone" EXACT [] xref: AAO:0000633 xref: FMA:9710 xref: MA:0001496 xref: MESH:D055172 xref: NCIT:C33888 xref: SCTID:272678009 xref: TAO:0000308 xref: UMLS:C0242403 {source="ncithesaurus:Vomer"} xref: Wikipedia:Vomer xref: ZFA:0000308 is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0011597 ! bone of upper jaw is_a: UBERON:0012071 ! palate bone relationship: connected_to UBERON:0001677 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! sphenoid bone relationship: connected_to UBERON:0001679 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! ethmoid bone relationship: contributes_to_morphology_of UBERON:0011156 ! facial skeleton relationship: part_of UBERON:0011085 ! palatoquadrate arch property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dermal bone that underlies the mesethmoid and inserts in a fossa on the anteroventral surface of the parasphenoid.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000308", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Paired, palatal bones of intramembranous origin that lie ventral to the olfactory region and help to floor the nasal capsules.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000633", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: overlaps autopalatine-vomer joint (TAO:0001784)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000308", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: overlaps mesethmoid-vomer joint (TAO:0001680)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000308", ontology="TAO"} property_value: UBPROP:0000003 "In bony fish, the vomers are flattened, paired, bones forming the anterior part of the roof of the mouth, just behind the premaxillary bones. In many species, they have teeth, supplementing those in the jaw proper; in some extinct species the teeth on the vomers were actually larger than the primary set. In amphibians and reptiles, the vomers become narrower, due to the presence of the enlarged choanae (the inner part of the nostrils) on either side, and they may extend further back in the jaw. They are typically small in birds, where they form the upper hind part of the beak, again being located between the choanae. In mammals, the vomers have become narrower still, and are fused into a single, vertically oriented bone. The development of the hard palate beneath the vomer means that the bone is now located in a nasal chamber, separate from the mouth[WP]" xsd:string {source="Wikipedia:Vomer#In_other_animals"} property_value: UBPROP:0000005 "The vomer is paired in some taxa (e.g., Amia) while unpaired in others (e.g., teleosts).[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0000308", ontology="TAO", source="Curator"} [Term] id: UBERON:0002397 name: maxilla namespace: uberon def: "The bone which normally forms the lateral upper jaw in osteichthyans, including tetrapods." [http://palaeos.com/vertebrates/glossary/glossaryM.html, Wikipedia:Maxilla] comment: Fusion of maxilla + premaxilla subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "maxillae" RELATED PLURAL [] synonym: "maxillary bone" RELATED [Wikipedia:Maxilla] synonym: "upper jaw bone" BROAD [] xref: AAO:0000285 xref: CALOHA:TS-2217 xref: EHDAA2:0001068 xref: EHDAA:8043 xref: EMAPA:17639 xref: FMA:9711 xref: GAID:220 xref: galen:Maxilla xref: MA:0001491 xref: MESH:D008437 xref: NCIT:C26470 xref: SCTID:181813003 xref: TAO:0000270 xref: UMLS:C0024947 {source="ncithesaurus:Maxilla"} xref: VHOG:0001021 xref: VSAO:0000207 xref: Wikipedia:Maxilla xref: ZFA:0000270 is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0008193 {source="FMA"} ! pneumatized bone is_a: UBERON:0008907 {source="VSAO"} ! dermal bone is_a: UBERON:0011597 ! bone of upper jaw is_a: UBERON:0015212 ! lateral structure relationship: adjacent_to UBERON:0002244 ! premaxilla relationship: contributes_to_morphology_of UBERON:0001708 ! jaw skeleton relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton relationship: part_of UBERON:0003113 {notes="facial series", source="ISBN:0073040584"} ! dermatocranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a7/Gray189.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dermal bone that forms part of the upper jaw, located antero-ventral to the premaxilla. The maxilla is a paired bone.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000270", ontology="TAO", source="TAO:GA_TG"} property_value: UBPROP:0000001 "Paired, intramembranous bone located on the lateral sides of the skull, posterior to the premaxillae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000285", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: overlaps autopalatine-maxillary joint (TAO:0001942)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000270", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: overlaps premaxillary-maxillary joint (TAO:0002260)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000270", ontology="TAO"} property_value: UBPROP:0000005 "In some teleosts, the maxilla is located postero-ventral to the supramaxilla. Commonly, the articular process of the maxilla articulates with the autopalatine and ethmoidal region antero-medially. The maxilla is usually the largest bone in the upper jaw assemblage.[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0000270", ontology="TAO", source="Curator"} property_value: UBPROP:0000007 "maxillary" xsd:string [Term] id: UBERON:0002398 name: manus namespace: uberon def: "Distal segment of the fore limb, including carpal region, metacarpal region and digits." [Wikipedia:Hand, Wikipedia:Manus_(anatomy)] subset: pheno_slim subset: uberon_slim synonym: "fore foot" NARROW INCONSISTENT [] synonym: "fore paw" NARROW SENSU [EMAPA:17428, OBOL:automatic] synonym: "fore-paw" NARROW SENSU [EMAPA:17428] synonym: "forefeet" NARROW PLURAL [] synonym: "forefoot" NARROW INCONSISTENT [] synonym: "forefoot of quadruped" NARROW [] synonym: "forelimb autopod" EXACT [OBOL:automatic] synonym: "forelimb autopodium" EXACT [OBOL:automatic] synonym: "forepaw" NARROW SENSU [MA:0000037] synonym: "hand" EXACT HUMAN_PREFERRED [MA:0000037] synonym: "hand region" EXACT [EHDAA2:0000728] synonym: "terminal segment of free upper limb" EXACT [] xref: AAO:0010803 xref: BTO:0004668 xref: CALOHA:TS-2213 xref: EHDAA2:0000728 xref: EMAPA:17428 xref: FMA:9712 xref: GAID:56 xref: galen:Hand xref: MA:0000037 xref: MESH:D006225 xref: NCIT:C32712 xref: NLXANAT:20090603 xref: SCTID:302539009 xref: UMLS:C0018563 {source="ncithesaurus:Hand"} xref: VHOG:0000344 xref: Wikipedia:Manus_(anatomy) is_a: UBERON:0002470 ! autopod region is_a: UBERON:0008785 ! upper limb segment intersection_of: UBERON:0002470 ! autopod region intersection_of: part_of UBERON:0002102 ! forelimb relationship: develops_from UBERON:0006875 ! embryonic handplate relationship: has_skeleton UBERON:0001442 ! skeleton of manus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/76/LeftHand0.jpg" xsd:anyURI property_value: IAO:0000232 "like all limb segments, this class encompasses both the unformed hand region of the embryo to the fully formed structure complete with skeleton" xsd:string property_value: UBPROP:0000007 "manual" xsd:string [Term] id: UBERON:0002400 name: parietal pleura namespace: uberon def: "The outer serous membrane of the pulmonary pleural." [UBERON:cjm, Wikipedia:Pulmonary_pleurae] comment: the part of the pleura external to the visceral pleura. It lines the inner surface of the chest wall, covers the diaphragm, and is reflected over the structures occupying the middle of the thorax subset: pheno_slim subset: uberon_slim synonym: "pleura parietalis" RELATED LATIN [Wikipedia:Parietal_pleura] xref: EMAPA:16776 xref: FMA:9733 xref: MA:0002488 xref: NCIT:C33273 xref: SCTID:361998003 xref: UMLS:C0225777 {source="ncithesaurus:Parietal_Pleura"} xref: VHOG:0001495 xref: Wikipedia:Parietal_pleura is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: adjacent_to UBERON:0002224 ! thoracic cavity intersection_of: part_of UBERON:0000977 ! pleura relationship: adjacent_to UBERON:0002224 ! thoracic cavity relationship: contributes_to_morphology_of UBERON:0000977 ! pleura relationship: innervated_by UBERON:0003727 ! intercostal nerve relationship: part_of UBERON:0000977 ! pleura [Term] id: UBERON:0002401 name: visceral pleura namespace: uberon def: "The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs." [UBERON:cjm, Wikipedia:Pulmonary_pleurae] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "lung mesothelium" RELATED [EHDAA2:0002205] synonym: "lung pleura" RELATED [] synonym: "pleura pulmonalis" EXACT LATIN [FMA:9734, FMA:TA] synonym: "pleura visceralis" EXACT LATIN [Wikipedia:Visceral_pleura] synonym: "pleura visceralis (pulmonalis)" EXACT [] synonym: "pulmonary pleura" RELATED INCONSISTENT [FMA:9734] synonym: "pulmonary visceral pleura" EXACT [] xref: EHDAA2:0002205 xref: EMAPA:16777 xref: FMA:9734 xref: MA:0002489 xref: NCIT:C33881 xref: SCTID:361997008 xref: UMLS:C0225776 {source="ncithesaurus:Visceral_Pleura"} xref: VHOG:0001496 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0022350 ! visceral serous membrane intersection_of: UBERON:0004923 ! organ component layer intersection_of: adjacent_to UBERON:0002048 ! lung intersection_of: part_of UBERON:0000977 ! pleura relationship: adjacent_to UBERON:0002048 ! lung relationship: attaches_to UBERON:0008946 ! lung parenchyma relationship: contributes_to_morphology_of UBERON:0000977 ! pleura relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000977 ! pleura relationship: part_of UBERON:0002048 {source="FMA"} ! lung property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Each lung is invested by an exceedingly delicate serous membrane, the pleura, which is arranged in the form of a closed invaginated sac. A portion of the serous membrane covers the surface of the lung and dips into the fissures between its lobes; it is called the pulmonary pleura (or visceral pleura). The visceral pleura is attached directly to the lungs[Wikipedia:Visceral_pleura]." xsd:string {source="Wikipedia:Visceral_pleura"} property_value: UBPROP:0000012 "FMA treats this as part of the lungs" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002402 name: pleural cavity namespace: uberon def: "The fluid-filled cavity that lies between the visceral and parietal pleurae." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Pleural_cavity] subset: pheno_slim subset: uberon_slim synonym: "cavitas pleuralis" EXACT LATIN [Wikipedia:Pleural_cavity] synonym: "cavitum pleuralae" RELATED LATIN [Wikipedia:Pleural_cavity] synonym: "cavitum pleurale" RELATED LATIN [Wikipedia:Pleural_cavity] xref: BTO:0004422 xref: EHDAA2:0001475 xref: EMAPA:16773 xref: EMAPA:16774 xref: FMA:9740 xref: GAID:95 xref: MA:0000055 xref: MESH:D035422 xref: NCIT:C12840 xref: SCTID:361999006 xref: UMLS:C0178802 {source="ncithesaurus:Pleural_Cavity"} xref: VHOG:0000581 xref: Wikipedia:Pleural_cavity is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0035809 ! serous cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0009778 ! pleural sac relationship: adjacent_to UBERON:0002400 ! parietal pleura relationship: adjacent_to UBERON:0002401 ! visceral pleura relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom relationship: luminal_space_of UBERON:0009778 ! pleural sac relationship: part_of UBERON:0009778 ! pleural sac property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ab/Gray965.png" xsd:anyURI property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000581", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"} property_value: UBPROP:0000009 "The contraction of the diaphragm creates a negative pressure within the pleural cavity which forces the lungs to expand resulting in passive exhalation and active inhalation. This breathing process can be made forceful through the contraction of the external intercostal muscles which forces the rib cage to expand and add to the negative pressure in the pleural cavity causing the lungs to fill with air. The fluid in the cavity provides lubrication and cushioning" xsd:string property_value: UBPROP:0000012 "the EHDAA2 class of the same is not equivalent. See https://github.com/obophenotype/uberon/issues/86" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0002405 name: immune system namespace: uberon def: "Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies." [Wikipedia:Immune_system] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim subset: vertebrate_core xref: AAO:0011003 xref: BILA:0000104 xref: BTO:0005810 xref: FMA:9825 xref: GAID:328 xref: MA:0002711 xref: MESH:D007107 xref: NCIT:C12735 xref: SCTID:362590003 xref: TAO:0001159 xref: UMLS:C0020962 {source="ncithesaurus:Immune_System"} xref: VHOG:0001247 xref: Wikipedia:Immune_system xref: XAO:0003152 xref: ZFA:0001159 is_a: UBERON:0015203 ! non-connected functional system disjoint_from: UBERON:0002416 ! integumental system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0002376 ! immune system process relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: protects UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "The antibody-based immune system defined by the presence of the major histocompatibility complex (MHC), T cell receptor (TCR), B cell receptor (BCR) or recombination activating genes (RAGs) is known beginning from jawed fishes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001247", ontology="VHOG", source="PMID:21046016 Dzik JM, The ancestry and cumulative evolution of immune reactions. Acta biochimica Polonica (2010)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002406 name: pericardial sac namespace: uberon def: "A double-walled sac containing the heart and the roots of the great vessels." [https://github.com/obophenotype/uberon/issues/86, Wikipedia:Pericardium] subset: uberon_slim subset: vertebrate_core synonym: "pericardium" RELATED [] xref: FMA:9868 xref: RETIRED_EHDAA2:0001443 xref: SCTID:361326002 xref: TAO:0000054 is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0005906 ! serous sac intersection_of: UBERON:0005906 ! serous sac intersection_of: has_part UBERON:0001074 ! pericardial cavity intersection_of: has_part UBERON:0002357 ! serous pericardium relationship: has_part UBERON:0001074 ! pericardial cavity relationship: has_part UBERON:0002357 ! serous pericardium relationship: part_of UBERON:0002407 ! pericardium relationship: surrounded_by UBERON:0002359 {source="FMA"} ! fibrous pericardium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI [Term] id: UBERON:0002407 name: pericardium namespace: uberon def: "The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Pericardium] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core xref: AAO:0010817 xref: BSA:0000090 xref: BTO:0000717 xref: CALOHA:TS-0761 xref: EFO:0000820 xref: EHDAA:5376 xref: EMAPA:16133 xref: EV:0100023 xref: FMA:9869 xref: GAID:569 xref: galen:Pericardium xref: MA:0000099 xref: MAT:0000454 xref: MESH:D010496 xref: NCIT:C13005 xref: RETIRED_EHDAA2:0001443 xref: SCTID:181295003 xref: TAO:0000054 xref: UMLS:C0031050 {source="ncithesaurus:Pericardium"} xref: VHOG:0001280 xref: Wikipedia:Pericardium xref: XAO:0004182 xref: ZFA:0000054 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000481 ! multi-tissue structure relationship: has_part UBERON:0002359 ! fibrous pericardium relationship: has_part UBERON:0002406 ! pericardial sac relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0015410 {source="MA"} ! heart plus pericardium relationship: surrounds UBERON:0002349 ! myocardium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI property_value: UBPROP:0000001 "Peritoneum that surrounds the heart.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010817", ontology="AAO", source="AAO:JMG"} property_value: UBPROP:0000007 "pericardial" xsd:string property_value: UBPROP:0000012 "In GO the concept of pericardium is developmental implicitly epithelial, but here it represents a multi-tissue structure encompassing the sac (epithelium plus connective) and cavity" xsd:string {external_ontology="FMA"} property_value: UBPROP:0000012 "this class denotes a combination of fibrous PC + PC sac (itself a combination of cavity, epithelium and connective tissue). Many sources use the term 'pericardium' to denote either just the serous membrane (ZFA) or the epithelium (GO)" xsd:string {external_ontology="ZFA"} property_value: UBPROP:0000012 "we follow FMA in dividing pericardium into pericardial sac and fibrous pericardium" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002408 name: parietal serous pericardium namespace: uberon def: "Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "lamina parietalis (pericardii serosum)" EXACT [] synonym: "lamina parietalis pericardii" EXACT LATIN [FMA:9870, FMA:TA] synonym: "parietal layer of serous pericardium" EXACT [] synonym: "parietal pericardium" EXACT [VHOG:0000537] synonym: "pericardial sac" RELATED INCONSISTENT [DOI:10.5962/bhl.title.1013] xref: EHDAA:3422 xref: EHDAA:5378 xref: EMAPA:19031 xref: FMA:9870 xref: MA:0000483 xref: NCIT:C94500 xref: SCTID:243956000 xref: UMLS:C0225969 {source="ncithesaurus:Parietal_Pericardium"} xref: VHOG:0000537 xref: Wikipedia:Parietal_pericardium is_a: UBERON:0022351 ! parietal serous membrane intersection_of: UBERON:0022351 ! parietal serous membrane intersection_of: part_of UBERON:0002357 ! serous pericardium relationship: attaches_to UBERON:0006670 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! central tendon of diaphragm relationship: part_of UBERON:0002357 ! serous pericardium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray489.png" xsd:anyURI [Term] id: UBERON:0002409 name: pericardial fluid namespace: uberon def: "Transudate contained in the pericardial cavity.[FMA]." [FMA:9887, Wikipedia:Pericardial_fluid] subset: uberon_slim xref: BTO:0001016 xref: FMA:9887 xref: MA:0002530 xref: MESH:D000069236 xref: Wikipedia:Pericardial_fluid is_a: UBERON:0007794 {source="FMA"} ! secretion of serous gland is_a: UBERON:0036217 ! coelomic fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0002425 ! visceral serous pericardium relationship: located_in UBERON:0001074 ! pericardial cavity relationship: produced_by UBERON:0002425 ! visceral serous pericardium [Term] id: UBERON:0002410 name: autonomic nervous system namespace: uberon def: "The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]." [GO:0048483] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "ANS" RELATED ABBREVIATION [] synonym: "autonomic division of peripheral nervous system" EXACT [FMA:65553] synonym: "autonomic part of peripheral nervous system" EXACT [FMA:65553] synonym: "divisio autonomica systematis nervosi peripherici" EXACT [FMA:TA] synonym: "divisio autonomica systematis nervosi peripherici" RELATED LATIN [Wikipedia:Autonomic_nervous_system] synonym: "pars autonomica systematis nervosi peripherici" EXACT [FMA:TA] synonym: "peripheral autonomic nervous system" EXACT [FMA:65553] synonym: "visceral nervous system" EXACT [] xref: AAO:0000033 xref: BIRNLEX:1123 xref: BTO:0002507 xref: CALOHA:TS-2001 xref: EHDA:10095 xref: EHDAA2:0000158 xref: EHDAA:3767 xref: EMAPA:16984 xref: FMA:65553 xref: GAID:706 xref: MA:0000219 xref: MESH:D001341 xref: NCIT:C12673 xref: neuronames:2054 xref: SCTID:362481007 xref: TAO:0001574 xref: UMLS:C0004388 {source="ncithesaurus:Autonomic_Nervous_System", source="BIRNLEX:1123"} xref: UMLS:C1305381 {source="BIRNLEX:1123"} xref: VHOG:0000396 xref: Wikipedia:Autonomic_nervous_system xref: ZFA:0001574 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: contributes_to_morphology_of UBERON:0001016 ! nervous system relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000010 {source="EMAPA", source="MA", source="NIFSTD", source="ZFA-modified-from-isa"} ! peripheral nervous system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f7/Gray839.png" xsd:anyURI property_value: UBPROP:0000001 "Nervous system including a portion of the central and peripheral systems and presiding over the control and coordination of the vegetative functions of the organism. It innervates smooth and cardiac muscles and glandular tissues and is responsible for many actions which are more or less automatic (e.g. secretion, vasoconstriction etc.). It consists of the sympathetic and parasympathetic nervous systems. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000396", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Part of the peripheral nervous system which regulates involuntary functions of the body and consists of the sympathetic and parasympathetic system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000033", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000003 "From comparative analyses of craniate brains, a morphotype of the brain in the earliest craniate stock can be constructed. In marked contrast to cephalochordates, the ancestral craniate morphotype had a plethora of unique features, which included a telencephalon with pallial and subpallial parts, paired olfactory bulbs with substantial projections to most or all of the telencephalic pallium, paired lateral eyes and ears, a lateral line system for both electroreception and mechanoreception, spinal cord dorsal root ganglia, and an autonomic nervous system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000396", ontology="VHOG", source="DOI:10.1002/1097-0185(20000615)261:3<111::AID-AR6>3.0.CO;2-F Butler AB, Chordate evolution and the origin of craniates: An old brain in a new head. AnaT Rec (New Anat) (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "FMA splits this into peripheral and nervous parts; GO has ANS directly under NS; PNS is a sib" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002411 name: clitoris namespace: uberon def: "The small, erectile body located at the anterior end of the vulva." [ISBN:0-683-40008-8, MP:0003127] subset: organ_slim subset: pheno_slim subset: uberon_slim xref: BTO:0002020 xref: EHDAA2:0000255 xref: EHDAA:9360 xref: EMAPA:30819 xref: FMA:9909 xref: GAID:385 xref: galen:Clitoris xref: MA:0000382 xref: MESH:D002987 xref: NCIT:C12308 xref: SCTID:181442003 xref: UMLS:C0008984 {source="ncithesaurus:Clitoris"} xref: VHOG:0000700 xref: Wikipedia:Clitoris is_a: UBERON:0000062 {source="Wikipedia"} ! organ is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: contributes_to_morphology_of UBERON:0005056 ! external female genitalia relationship: develops_from UBERON:0005876 {source="EHDAA2", source="Wikipedia"} ! undifferentiated genital tubercle relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: part_of UBERON:0000997 {source="MA"} ! mammalian vulva property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/cf/Clitoris_anatomy_labeled-en.svg" xsd:anyURI property_value: UBPROP:0000007 "clitoral" xsd:string [Term] id: UBERON:0002412 name: vertebra namespace: uberon def: "The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165, VSAO:0000184] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "vertebra bone" EXACT [] synonym: "vertebrae" EXACT PLURAL [PHENOSCAPE:ad] xref: AAO:0000691 xref: CALOHA:TS-2352 xref: EFO:0001371 xref: EMAPA:32740 xref: FMA:9914 xref: galen:Vertebra xref: MA:0000309 xref: NCIT:C12933 xref: SCTID:181817002 xref: TAO:0001189 xref: UMLS:C0549207 {source="ncithesaurus:Vertebra"} xref: Wikipedia:Vertebra xref: XAO:0004019 xref: ZFA:0001189 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0008001 {source="FMA"} ! irregular bone is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0011094 ! vertebra cartilage element property_value: editor_note "Consider changing name to make distinction from inferred superclass 'vertebral element' clear" xsd:string property_value: editor_note "we follow FMA in making this an irregular bone - however vertebra have 'epiphyses' which are currently classified as belonging to long bones" xsd:string property_value: RO:0002161 NCBITaxon:7901 {source="Wikipedia"} property_value: UBPROP:0000001 "Endochondral bone that forms around the notochord and is part of the vertebral column.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001189", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Main component of the vertebral column. It consists of two essential parts, a dorsal neural arch and a ventral centrum.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000691", ontology="AAO", source="AAO:Pugener_and_Maglia_2008"} [Term] id: UBERON:0002413 name: cervical vertebra namespace: uberon def: "A vertebra that is located in the cervical region of the vertebral column." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "cervical vertebrae" EXACT PLURAL [] synonym: "vertebrae cervicales" RELATED LATIN [Wikipedia:Cervical_vertebrae] xref: EMAPA:17674 xref: FMA:9915 xref: GAID:235 xref: galen:CervicalVertebra xref: MA:0000311 xref: MESH:D002574 xref: NCIT:C12693 xref: SCTID:181820005 xref: Wikipedia:Cervical_vertebrae xref: XAO:0003076 is_a: UBERON:0003458 ! neck bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0004451 {is_inferred="true"} ! trunk or cervical vertebra is_a: UBERON:0015007 ! cervical vertebra endochondral element intersection_of: UBERON:0015007 ! cervical vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0013505 ! cervical vertebra cartilage element property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f8/Illu_vertebral_column.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In some species, some parts of the skull may be composed of vertebra-like elements, e.g. the occipital bone in humans is composed of four vertebra-like segments. In many vertebrate species, cervical vertebrae are variable in number; however, almost all mammals have seven (including those with very short necks relative to body size, such as elephants or whales, and those with very long necks, such as giraffes). The few exceptions include the manatee and the sloths, of which the two-toed sloth has six cervical vertebrae and the three-toed sloth has up to nine cervical vertebrae. In many species, though not in mammals, the cervical vertebrae bear ribs. In many other groups, such as lizards and saurischian dinosaurs, the cervical ribs are large; in birds they are small and completely fused to the vertebrae. The transverse processes of mammals are homologous to the cervical ribs of other amniotes. Thoracic vertebrae in all species are defined as those vertebrae which also carry a pair of ribs, and lie caudal to the cervical vertebrae. In humans, cervical vertebrae are the smallest of the true vertebrae, and can be readily distinguished from those of the thoracic or lumbar regions by the presence of a foramen (hole) in each transverse process, through which passes the vertebral artery." xsd:string [Term] id: UBERON:0002414 name: lumbar vertebra namespace: uberon def: "Large vertebra of the movable part of the vertebral column, characterized by the absence of the foramen transversarium within the transverse process, and by the absence of facets on the sides of the body." [Wikipedia:Lumbar_vertebrae] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim xref: CALOHA:TS-2364 xref: EMAPA:18007 xref: FMA:9921 xref: GAID:240 xref: galen:LumbarVertebra xref: MA:0000312 xref: MESH:D008159 xref: NCIT:C12744 xref: SCTID:181822002 xref: UMLS:C0024091 {source="ncithesaurus:Lumbar_Vertebra"} xref: Wikipedia:Lumbar_vertebrae is_a: UBERON:0002412 ! vertebra is_a: UBERON:0003828 ! abdominal segment bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0015009 ! lumbar vertebra endochondral element intersection_of: UBERON:0015009 ! lumbar vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0013509 ! lumbar vertebra cartilage element property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c8/Gray93.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "Whereas all rats had six lumbar vertebrae, variable patterns in mice included mostly five vertebrae in DBA/2J, mostly six vertebrae in C57BL/6J, and a mix in B6129PF2/J" xsd:string {source="PMCID:PMC2700063"} [Term] id: UBERON:0002415 name: tail namespace: uberon def: "An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail." [AEO:0000109, Wikipedia:Tail] subset: efo_slim subset: grouping_class subset: pheno_slim subset: uberon_slim synonym: "caudal subdivision" EXACT [https://orcid.org/0000-0002-6601-2165] xref: AEO:0000109 xref: BILA:0000117 xref: BTO:0001348 xref: EFO:0000963 xref: EHDAA:9198 xref: GAID:1245 xref: MAT:0000094 xref: MESH:D013623 xref: MIAA:0000094 xref: WBbt:0005741 xref: Wikipedia:Tail is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0000154 ! posterior region of body property_value: editor_note "Note we also have a subclass post-anal tail, for the chordate specific structure. currently defined very generally, inclusive of caudal fin" xsd:string property_value: RO:0002161 NCBITaxon:9606 [Term] id: UBERON:0002416 name: integumental system namespace: uberon alt_id: UBERON:0007029 def: "Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle." [CARO:0002001, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/29] subset: efo_slim subset: grouping_class subset: pheno_slim synonym: "body surface" RELATED [] synonym: "dermal system" RELATED [MIAA:0000033] synonym: "external covering of organism" RELATED [] synonym: "integumentary system" EXACT [FMA:72979] synonym: "integumentum commune" RELATED LATIN [Wikipedia:Integumentary_system] synonym: "organism surface" RELATED [EHDAA2:0003154] synonym: "surface" RELATED [BILA:0000118] xref: AEO:0000154 xref: BILA:0000118 xref: CALOHA:TS-1299 xref: CARO:0002001 xref: EFO:0000807 xref: EHDAA2:0000836 xref: EHDAA2_RETIRED:0003154 xref: EHDAA:6520 xref: EMAPA:17524 xref: EV:0100151 xref: FBbt:00004969 xref: FMA:72979 xref: galen:Surface xref: HAO:0000421 xref: MA:0000014 xref: MAT:0000033 xref: MESH:D034582 xref: MIAA:0000033 xref: NCIT:C12907 xref: SCTID:361692004 xref: TADS:0000108 xref: UMLS:C0037267 {source="ncithesaurus:Integumentary_System"} xref: VHOG:0000403 xref: Wikipedia:Integumentary_system xref: XAO:0000176 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:0002423 ! hepatobiliary system disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: bounding_layer_of UBERON:0000468 ! multicellular organism relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0007376 ! outer epithelium relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/tfhayamizu relationship: surrounded_by UBERON:0013514 ! space surrounding organism property_value: UBPROP:0000003 "(...) the integument of many tetrapods is reinforced by a morphologically and structurally diverse assemblage of skeletal elements. These elements are widely understood to be derivatives of the once all-encompassing dermal skeleton of stem-gnathostomes (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000403", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2008.01043.x Vickaryous MK, Sire JY, The integumentary skeleton of tetrapods: origin, evolution, and development. J Anat (2009)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002417 name: abdominal segment of trunk namespace: uberon def: "The abdominal segment of the torso." [Wikipedia:Lumbar] synonym: "abdomen/pelvis/perineum" RELATED [MA:0000021] synonym: "lower body" RELATED [MA:0000021] synonym: "lower trunk" RELATED [FMA:259211] synonym: "lumbar region" RELATED [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:35104 xref: FMA:259211 xref: MA:0000021 xref: SCTID:362875007 xref: Wikipedia:Lumbar is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk is_a: UBERON:0011676 ! subdivision of organism along main body axis [Term] id: UBERON:0002418 name: cartilage tissue namespace: uberon def: "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/37, https://sourceforge.net/p/obo/vertebrate-skeletal-anatomy-vsao-term-requests/5, PSPUB:0000170, VSAO:0000040] comment: Previous: "A portion of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate[GO]. Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage[FMA]. an avascular supporting and articular skeletal tissue. It also functions as the primary endoskeletal support in vertebrate embryos. Cartilage is deposited by and is composed of chondroblasts and chondrocytes separated by an extracellular matrix, which may or may not mineralize depending on cartilage type, age, or taxon[Hall and Witten]." See also FMA:71500 Set of cartilages, FMA:55107 Cartilage organ, FMA:12264 Articular cartilage. // elements made from cartilage, cartilage-like, or chondroid tissues evolved in invertebrates[H&W] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "cartilage" RELATED [] synonym: "cartilage tissue" EXACT [FMA:37377] synonym: "cartilages" RELATED [VHOG:0001207] synonym: "cartilaginous tissue" EXACT [] synonym: "chondrogenic tissue" EXACT [VSAO:0000040] synonym: "portion of cartilage tissue" RELATED [FMA:37377] xref: AAO:0000060 xref: AEO:0000087 xref: BTO:0000206 xref: EFO:0000949 xref: EHDAA2:0003087 xref: EMAPA:32730 xref: EV:0100141 xref: FMA:37377 xref: GAID:99 xref: galen:Cartilage xref: MA:0000104 xref: MAT:0000189 xref: MESH:D002356 xref: MIAA:0000189 xref: NCIT:C12373 xref: NCIT:C32268 xref: SCTID:309312004 xref: TAO:0001501 xref: UMLS:C0007301 {source="ncithesaurus:Cartilage"} xref: VHOG:0001207 xref: VSAO:0000040 xref: Wikipedia:Cartilage xref: XAO:0000170 xref: ZFA:0005622 is_a: UBERON:0004755 ! skeletal tissue disjoint_from: UBERON:0002481 {source="https://github.com/obophenotype/uberon/issues/117"} ! bone tissue relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system relationship: has_part CHEBI:18085 ! glycosaminoglycan relationship: has_part CL:0000138 ! chondrocyte relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI property_value: UBPROP:0000001 "A type of dense connective tissue. It is composed of cells called chondrocytes which are dispersed in a firm gel-like ground substance, called the matrix. Cartilage is avascular (contains no blood vessels) and nutrients are diffused through the matrix. Cartilage is found in the joints, the rib cage, the ear, the nose, in the throat and between intervertebral disks. It makes up virtually the entire skeleton in chondrichthyes.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000060", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "Portion of tissue which is connective tissue composed of collagen and/or elastin fibers and chondrocytes. Cartilage is avascular and provides both skeletal functions and a framework upon which bone is deposited.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001501", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000040", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} property_value: UBPROP:0000002 "relationship loss: subclass specialized connective tissue (AAO:0000571)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000060", ontology="AAO"} property_value: UBPROP:0000003 "Phylogenetic analysis suggests that cartilage arose independently in cnidarians, hemichordates, vertebrates, arthropods, annelids, brachiopods, and molluscs - or a common ancestor of brachiopods and molluscs (...). Analyses of cartilage as a tissue and of the development of invertebrate cartilages are consistent with homology between invertebrate and vertebrate cartilage. From the discussion above, it will be clear that understanding genetic changes underlying cartilage evolution is key to determining whether the multiple origins of cartilage represent parallel evolution.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001207", ontology="VHOG", source="DOI:10.1111/j.1525-142X.2011.00520.x Hall BK, Parallelism, deep homology, and evo-devo. Evolution and Development (2012)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002419 name: skin gland namespace: uberon def: "A gland that is part of a skin of body [Automatically generated definition]." [OBOL:automatic] subset: organ_slim synonym: "glandulae cutis" EXACT LATIN [FMA:71878, FMA:TA] synonym: "set of skin glands" RELATED [FMA:71878] synonym: "skin glands" RELATED PLURAL [] synonym: "skin glands set" RELATED PLURAL [] xref: EMAPA:35774 xref: FMA:71878 xref: MA:0000146 xref: SCTID:110485007 is_a: UBERON:0003297 ! gland of integumental system is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0006003 ! integumentary adnexa intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002097 ! skin of body relationship: part_of UBERON:0002097 ! skin of body property_value: editor_note "check FMA, use plural for now as general class not there" xsd:string [Term] id: UBERON:0002423 name: hepatobiliary system namespace: uberon def: "The part of the digestive system that contains the liver and the biliary system." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "hepaticobiliary system" EXACT [GO:0061008] synonym: "liver and biliary system" EXACT [] synonym: "liver/biliary system" RELATED [] xref: AAO:0011056 xref: CALOHA:TS-1308 xref: EFO:0000800 xref: EHDAA2:0000998 xref: EHDAA:2189 xref: EMAPA:16840 xref: EV:0100088 xref: MA:0000324 xref: MAT:0000024 xref: MIAA:0000024 xref: NCIT:C43612 xref: TAO:0000036 xref: UMLS:C1711359 {source="ncithesaurus:Hepatobiliary_System"} xref: VHOG:0000294 xref: Wikipedia:Hepatobiliary_system xref: XAO:0000132 xref: ZFA:0000036 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0011216 ! organ system subdivision disjoint_from: UBERON:0004456 ! entire sense organ system disjoint_from: UBERON:8450002 ! excretory system relationship: capable_of GO:0061007 ! hepaticobiliary system process relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0002107 ! liver relationship: has_part UBERON:0002294 ! biliary system relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001007 ! digestive system property_value: UBPROP:0000001 "System responsible for the production and movement of bile[ZFIN:curator]." xsd:string {source="ZFIN:curator"} property_value: UBPROP:0000009 "The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. The parts are: liver, bile duct, gall bladder and hepatic duct [GO:0061008]" xsd:string [Term] id: UBERON:0002424 name: oral epithelium namespace: uberon def: "An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues." [https://orcid.org/0000-0002-6601-2165] subset: vertebrate_core synonym: "epithelium of mucosa of mouth" EXACT [FMA:265152] synonym: "epithelium of oral mucosa" EXACT [FMA:265152] xref: AAO:0010357 xref: BTO:0001775 xref: CALOHA:TS-0715 xref: EHDAA2:0001325 xref: EHDAA:2187 xref: EMAPA:16839 xref: EMAPA:26942 xref: FMA:265152 xref: MA:0000344 xref: NCIT:C49595 xref: TAO:0000816 xref: UMLS:C1709332 {source="ncithesaurus:Oral_Cavity_Epithelium"} xref: VHOG:0000187 xref: XAO:0003201 xref: ZFA:0000816 is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0006915 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! stratified squamous epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003729 ! mouth mucosa relationship: adjacent_to UBERON:0000167 {source="AAO-modified"} ! oral cavity relationship: part_of UBERON:0003729 ! mouth mucosa property_value: editor_note "consider including separate class for developmental structure (adult human is stratified; in EHDAA2 is unilaminar)" xsd:string property_value: UBPROP:0000001 "The epithelium that lines the oral cavity. The oral epithelium epithelial cells with many short microvilli as well as mucous cells, rodlet cells and taste buds[ZFIN:ZDB-PUB-060921-12, ZFIN:ZDB-PUB-091204-24]." xsd:string {source="ZFA:0000816"} property_value: UBPROP:0000011 "the avian oral epithelium has the developmental capacity to initiate tooth developmental programs with underlying grafts of non-avian oral ectomesenchyme" xsd:string {source="PMID:16488870"} [Term] id: UBERON:0002425 name: visceral serous pericardium namespace: uberon def: "Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]." [Wikipedia:Visceral_pericardium] subset: pheno_slim subset: uberon_slim synonym: "epicardium" RELATED [MA:0000484] synonym: "lamina visceralis pericardii serosi" EXACT LATIN [Wikipedia:Epicardium] synonym: "pericardium visceral mesothelium" RELATED [EMAPA:16589] synonym: "serous visceral pericardium" EXACT [] synonym: "visceral lamina of serous pericardium" EXACT [] synonym: "visceral layer of serous pericardium" EXACT [] synonym: "visceral pericardium" EXACT [VHOG:0000538] xref: EMAPA:16589 xref: EMAPA:19032 xref: FMA:84882 xref: MA:0000484 xref: SCTID:243955001 xref: VHOG:0000538 xref: Wikipedia:Visceral_pericardium is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0022350 ! visceral serous membrane intersection_of: UBERON:0022350 ! visceral serous membrane intersection_of: part_of UBERON:0002357 ! serous pericardium relationship: attaches_to UBERON:0002349 {source="FMA"} ! myocardium relationship: contributes_to_morphology_of UBERON:0002407 ! pericardium relationship: has_part UBERON:0002348 {source="cjm"} ! epicardium relationship: part_of UBERON:0002357 ! serous pericardium [Term] id: UBERON:0002427 name: arm skin namespace: uberon def: "A zone of skin that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "brachial region skin" RELATED [OBOL:automatic] synonym: "skin of arm" EXACT [OBOL:automatic] xref: EMAPA:37350 {source="MA:th"} xref: MA:0000596 xref: NCIT:C52754 xref: UMLS:C0222204 {source="ncithesaurus:Arm_Skin"} is_a: UBERON:0003531 ! forelimb skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm [Term] id: UBERON:0002428 name: limb bone namespace: uberon def: "A bone that is part of a limb [Automatically generated definition]." [OBOL:automatic] subset: efo_slim subset: pheno_slim synonym: "bone of extremity" EXACT [] synonym: "bone of limb" EXACT [OBOL:automatic] synonym: "free limb bone" EXACT [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] xref: EFO:0000945 xref: MAT:0000151 xref: MIAA:0000151 xref: NCIT:C32223 xref: SCTID:304149004 xref: UMLS:C0582791 {source="ncithesaurus:Bone_of_the_Extremity"} is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0004375 ! bone of free limb or fin is_a: UBERON:0015061 ! limb endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002101 ! limb relationship: develops_from UBERON:0010881 ! limb cartilage element property_value: IAO:0000232 "the formal definition is very inclusive, and includes sesamoids" xsd:string property_value: UBPROP:0000012 "NCITA includes clavicle. MA:'limb bone' is actually a bone of limb or girdle" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0002437 name: cerebral hemisphere white matter namespace: uberon def: "White matter that is part of a cerebral hemisphere." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "cerebral hemisphere white matter" EXACT [] synonym: "cerebral white matter" EXACT [MA:0000945] synonym: "hemisphere white matter" RELATED [] synonym: "region of cerebral white matter" RELATED [FMA:256174] synonym: "substantia medullaris cerebri" RELATED LATIN [NeuroNames:189] synonym: "white matter structure of cerebral hemisphere" EXACT [FMA:61822] xref: BAMS:cw xref: BIRNLEX:711 xref: BTO:0000236 xref: CALOHA:TS-2362 xref: EMAPA:35237 xref: FMA:241998 xref: FMA:256174 xref: FMA:61822 xref: MA:0000945 xref: NCIT:C49347 xref: neuronames:189 {source="BIRNLEX:711"} xref: SCTID:361691006 xref: UMLS:C0152295 {source="ncithesaurus:Cerebral_White_Matter", source="BIRNLEX:711"} xref: UMLS:C1284115 {source="BIRNLEX:711"} is_a: UBERON:0011299 ! white matter of telencephalon intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0001869 ! cerebral hemisphere property_value: IAO:0000232 "sometimes the term 'cerebral white matter' may be used generically but here is refers specifically to the white matter in a hemisphere" xsd:string property_value: UBPROP:0000012 "The BTO class is inconsistent as it is part of the brain and spinal cord." xsd:string {external_ontology="BTO"} [Term] id: UBERON:0002443 name: choroidal blood vessel namespace: uberon def: "A blood vessel that is part of a choroid [Automatically generated definition]." [OBOL:automatic] comment: cannot find singular in FMA, using Set class subset: pheno_slim synonym: "blood vessel of choroid" EXACT [OBOL:automatic] synonym: "blood vessel of choroid coat" EXACT [OBOL:automatic] synonym: "blood vessel of choroidea" EXACT [OBOL:automatic] synonym: "blood vessel of posterior uvea" EXACT [OBOL:automatic] synonym: "choroid blood vessel" EXACT [OBOL:automatic] synonym: "choroid blood vessels" EXACT [] synonym: "choroid blood vessels set" EXACT [] synonym: "choroid coat blood vessel" EXACT [OBOL:automatic] synonym: "choroidea blood vessel" EXACT [OBOL:automatic] synonym: "posterior uvea blood vessel" EXACT [OBOL:automatic] synonym: "set of choroid blood vessels" RELATED [FMA:76550] synonym: "vasa sanguinea choroideae" EXACT LATIN [FMA:76550, FMA:TA] xref: EMAPA:17828 xref: FMA:76550 xref: MA:0001237 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001776 ! optic choroid relationship: part_of UBERON:0001776 ! optic choroid [Term] id: UBERON:0002445 name: ulnare namespace: uberon def: "The postaxial bone of the proximal carpal region. Found in close approximation to the ulna, often in articulation[PHENOSCAPE:ad]." [https://github.com/obophenotype/uberon/issues/114, PHENOSCAPE:ad] subset: human_reference_atlas subset: uberon_slim synonym: "cuneiform bone of hand" EXACT [] synonym: "cuneiform bone of manus" EXACT [] synonym: "cuneiform of hand" RELATED [MA:0001347] synonym: "os triquetrum" EXACT LATIN [FMA:23715, FMA:TA] synonym: "os ulnare" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "triangular" RELATED [MA:0001347] synonym: "triangular bone" EXACT [] synonym: "triquetral" EXACT [MA:0001347, NCBITaxon:9606] synonym: "triquetral bone" EXACT [] synonym: "triquetrum" RELATED [MA:0001347] synonym: "ulnar carpal bone" RELATED [MA:0001347] xref: AAO:0000845 xref: EMAPA:36167 xref: FMA:23715 xref: galen:Triquetral xref: MA:0001347 xref: NCIT:C12858 xref: SCTID:181965000 xref: UMLS:C0223739 {source="ncithesaurus:Triangular_Bone"} xref: Wikipedia:Triquetral is_a: UBERON:0001480 ! proximal carpal bone intersection_of: UBERON:0001480 ! proximal carpal bone intersection_of: proximally_connected_to UBERON:0001424 ! ulna relationship: connected_to UBERON:0001424 {gci_relation="part_of", gci_filler="NCBITaxon:8292", notes="Amphibia", source="AAO", source="Wikipedia"} ! ulna relationship: connected_to UBERON:0001428 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="Wikipedia"} ! intermedium relationship: connected_to UBERON:0001429 {gci_relation="part_of", gci_filler="NCBITaxon:9606", connected_by="UBERON:0011870 or UBERON:0011869", source="Wikipedia"} ! pisiform relationship: connected_to UBERON:0001433 {gci_relation="part_of", gci_filler="NCBITaxon:9606", notes="hamate", source="Wikipedia"} ! distal carpal bone 4 relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: postaxialmost_part_of UBERON:0009880 ! carpal skeleton relationship: proximally_connected_to UBERON:0001424 ! ulna property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/Carpus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "One of two element that constitute the basal row of carpals. It articulates with the ulna, radius, radiale, centrale (element Y), and carpal 5(4). This element originates from one condensation center or the fusion of two elements (ulnare and intermedium). Occasionally it may fuse to carpal 5(4), the radiale, or other elements.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000845", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000013 "this bone is termed the triquetral bone in some mammalian taxa, notably humans" xsd:string [Term] id: UBERON:0002446 name: patella namespace: uberon def: "A large sesamoid bone found in the distal femur/proximal tibial region of the hindlimb of tetrapods. The patella is the attachment site for proximal hindlimb tendons.[PHENOSCAPE:ad]." [https://sourceforge.net/tracker/?func=detail&atid=1205376&aid=3470151&group_id=76834, PHENOSCAPE:ad] comment: The patella, also known as the knee cap or kneepan, is the largest sesamoid bone in the human body. The primary functional role of the patella is knee extension. The patella has convergently evolved in placental mammals and birds; marsupials have only rudimentary, non-ossified patellae. In more primitive tetrapods, including living amphibians and reptiles, the muscle tendons from the upper leg are attached directly to the tibia, and the patella is not present. See also: fabella. subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "knee bone" RELATED [FMA:24485] synonym: "knee cap" RELATED [Wikipedia:Patella] synonym: "patella" RELATED LATIN [Wikipedia:Patella] xref: EMAPA:35668 xref: FMA:24485 xref: GAID:203 xref: galen:Patella xref: MA:0001374 xref: MESH:D010329 xref: NCIT:C33282 xref: SCTID:182083008 xref: UMLS:C0030647 {source="ncithesaurus:Patella"} xref: Wikipedia:Patella is_a: UBERON:0001479 {source="FMA"} ! sesamoid bone is_a: UBERON:0005893 ! leg bone is_a: UBERON:0011141 ! appendicular ossicle intersection_of: UBERON:0001474 ! bone element intersection_of: connected_to UBERON:0000981 ! femur intersection_of: part_of UBERON:0001465 ! knee relationship: adjacent_to UBERON:0001485 ! knee joint relationship: connected_to UBERON:0000981 ! femur relationship: part_of UBERON:0001465 ! knee property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "patellar" xsd:string [Term] id: UBERON:0002450 name: decidua namespace: uberon def: "The maternal uterine-derived portion of the placenta." [MP:0004256, PMID:11433360] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "decidous membrane" EXACT [FMA:85538] synonym: "decidua basalis" RELATED [] synonym: "endometrium" RELATED [] synonym: "extraembryonic part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "extraembryonic placenta" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "maternal decidual layer" RELATED [MP:0004256] synonym: "maternal part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "maternal placenta" RELATED [EMAPA:35269, GOC:dph] synonym: "placenta maternal decidual layer" RELATED [] synonym: "uterine decidua" RELATED [BTO:0001360] xref: BTO:0001360 xref: CALOHA:TS-0193 xref: EMAPA:35269 xref: FMA:85538 xref: GAID:378 xref: MA:0001722 xref: MAT:0000290 xref: MESH:D003656 xref: MIAA:0000290 xref: NCIT:C32425 xref: SCTID:362842004 xref: UMLS:C0011106 {source="ncithesaurus:Decidua"} xref: Wikipedia:Decidua is_a: UBERON:0000478 {source="FMA"} ! extraembryonic structure relationship: contributes_to_morphology_of UBERON:0001987 ! placenta relationship: develops_from UBERON:0000459 ! uterine wall relationship: part_of UBERON:0001987 {component="maternal", source="MA"} ! placenta property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/fa/Gray33.png" xsd:anyURI property_value: editor_note "TODO - check mp syn" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000011 "formed under the influence of progesterone and forms highly-characteristic cells. [Wikipedia:Decidua]" xsd:string [Term] id: UBERON:0002451 name: endometrial gland namespace: uberon def: "The mucous secreting gland associated with the mucuous membrane lining the uterus." [Wikipedia:Uterine_glands] subset: human_reference_atlas subset: organ_slim subset: pheno_slim subset: uberon_slim synonym: "endometrial gland" EXACT [BTO:0003433] synonym: "endometrial mucuous gland" EXACT [] synonym: "endometrium gland" EXACT [] synonym: "glandulae uterinae" EXACT LATIN [FMA:71647, FMA:TA] synonym: "glandulae uterinae" RELATED LATIN [Wikipedia:Uterine_glands] synonym: "uterine gland" EXACT [] xref: BTO:0003433 xref: BTO:0004518 xref: EMAPA:29919 xref: MA:0001726 xref: NCIT:C33842 xref: SCTID:361377009 xref: UMLS:C1183035 {source="ncithesaurus:Uterine_Gland"} xref: Wikipedia:Uterine_glands is_a: UBERON:0000414 {source="MP"} ! mucous gland is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0005398 ! female reproductive gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001295 ! endometrium relationship: has_quality PATO:0002299 {source="Wikipedia:Tubular_gland"} ! tubular relationship: part_of UBERON:0012276 ! endometrium glandular epithelium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray1169.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000010 "simple or branched tubular" xsd:string property_value: UBPROP:0000202 FMA:71647 [Term] id: UBERON:0002457 name: intersomitic artery namespace: uberon alt_id: UBERON:0006001 def: "The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries." [MP:0010662] subset: pheno_slim subset: vertebrate_core synonym: "intersegmental arteries" RELATED PLURAL [ZFA:0001061] synonym: "intersegmental artery" EXACT [ZFA:0001061] xref: EHDAA2:0000882 xref: EHDAA:4340 xref: EMAPA:17616 xref: MA:0001985 xref: SCTID:360401001 xref: TAO:0001061 xref: VHOG:0000225 xref: XAO:0004165 xref: ZFA:0001061 is_a: UBERON:0001637 ! artery is_a: UBERON:0014907 ! intersomitic vessel property_value: UBPROP:0000001 "Arteries that connect the dorsal aorta and the dorsal longitudinal anastomotic vessel. They run along the vertical myotomal boundaries. At early stages these vessels don't have venous or arteriproperty_value external_definitionmarkers. They form from the primary sprouts from the dorsal aorta[ZFA:0001061]." xsd:string {source="ZFA:0001061"} property_value: UBPROP:0000003 "Few changes of evolutionary significance occur in the branching pattern of the dorsal aorta. All vertebrates have (...) paired intersegmental arteries to the trunk, tail, and paired appendages.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000225", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.612", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002458 name: spinal artery namespace: uberon def: "Arteries that supply the spinal cord." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Spinal_artery] subset: uberon_slim subset: vertebrate_core synonym: "spinal arteries" EXACT PLURAL [ZFA:0000682] xref: EHDAA2:0001890 xref: EHDAA:4355 xref: EMAPA:18241 xref: MA:0002043 xref: NCIT:C33587 xref: SCTID:244228006 xref: TAO:0000682 xref: UMLS:C0447043 {source="ncithesaurus:Spinal_Artery"} xref: Wikipedia:Spinal_artery xref: ZFA:0000682 is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002240 ! spinal cord relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0002240 ! spinal cord [Term] id: UBERON:0002460 name: vesical vein namespace: uberon def: "A tributary of the iliac vein that drains the urinary bladder." [UBERON:cjm, Wikipedia:Vesical_veins] subset: human_reference_atlas subset: uberon_slim synonym: "venae vesicales" EXACT LATIN [FMA:70911, FMA:TA] synonym: "vesical veins" EXACT PLURAL [] synonym: "vesical veins set" EXACT [] xref: EMAPA:37205 {source="MA:th"} xref: MA:0002263 xref: SCTID:12683000 xref: Wikipedia:Vesical_veins is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001255 ! urinary bladder relationship: drains UBERON:0001255 ! urinary bladder relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0001317 ! internal iliac vein property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/bd/Gray585.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000202 FMA:70911 [Term] id: UBERON:0002466 name: intestine secretion namespace: uberon def: "Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine." [Wikipedia:Succus_entericus] subset: pheno_slim subset: uberon_slim synonym: "intestinal juice" RELATED [BTO:0000644] synonym: "intestinal secretion" EXACT [FMA:62974] synonym: "succus entericus" EXACT [Wikipedia:Succus_entericus] xref: BTO:0000644 xref: FMA:62974 xref: GAID:1162 xref: MA:0002515 xref: MESH:D007419 xref: NCIT:C32875 xref: UMLS:C0021849 {source="ncithesaurus:Intestinal_Secretion"} xref: Wikipedia:Succus_entericus is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0000160 ! intestine relationship: produced_by UBERON:0000160 ! intestine [Term] id: UBERON:0002469 name: esophagus mucosa namespace: uberon alt_id: UBERON:0003345 def: "A mucosa that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal mucosa" EXACT [] synonym: "esophageal mucous membrane" EXACT [] synonym: "esophagus mucosa" EXACT [FMA:62996] synonym: "esophagus mucous membrane" EXACT [OBOL:automatic] synonym: "lamina muscularis mucosae oesophageae" EXACT LATIN [FMA:62996, FMA:TA] synonym: "mucosa of esophagus" EXACT [OBOL:automatic] synonym: "mucosa of oesophagus" EXACT [OBOL:automatic] synonym: "mucous membrane of esophagus" EXACT [] synonym: "mucous membrane of oesophagus" EXACT [FMA:62996] synonym: "muscularis mucosae of oesophagus" RELATED INCONSISTENT [FMA:62996] synonym: "oesophageal mucosa" EXACT [FMA:62996] synonym: "oesophagus mucosa" EXACT [] synonym: "oesophagus mucous membrane" EXACT [OBOL:automatic] synonym: "tunica mucosa esophagi" EXACT [] synonym: "tunica mucosa oesophageae" EXACT LATIN [FMA:62996, FMA:TA] synonym: "tunica mucosa oesophagi" EXACT [] synonym: "tunica mucosa oesophagi" RELATED [BTO:0002859] xref: BTO:0002859 xref: EMAPA:26981 xref: FMA:62996 xref: MA:0002680 xref: MESH:D000071041 xref: NCIT:C32538 xref: SCTID:362127004 xref: UMLS:C0227176 {source="ncithesaurus:Esophageal_Mucosa"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 ! wall of esophagus [Term] id: UBERON:0002470 name: autopod region namespace: uberon def: "Terminal segment of free limb, immediately distal to the zeugopod region. The fully developed autopod consists of the autopod skeleton plus associated structures such as integument, muscle tissue, vasculature etc. The autopod is divided into mesopodial, metapodiual, and acropodial segments. Examples: human hand, mouse paw, human foot." [https://github.com/obophenotype/uberon/issues/303, https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "autopod" BROAD [MA:0002714] synonym: "autopodial element" RELATED [] synonym: "autopodial limb segment" EXACT [MA:th] synonym: "autopodial segment" EXACT [] synonym: "autopodium" EXACT [] synonym: "autopodium region" EXACT [] synonym: "distal free limb segment" EXACT [FMA:83015] synonym: "distal segment of free limb" EXACT [FMA:83015] synonym: "distal segment of limb" RELATED [EMAPA:32722] synonym: "manus/pes" RELATED [] synonym: "paw" RELATED [] synonym: "paw/hand/foot/hoof" RELATED [] synonym: "pod" RELATED [] xref: BTO:0004359 xref: EFO:0000877 xref: EMAPA:32722 xref: FMA:83015 xref: MA:0002714 xref: MAT:0000091 xref: MIAA:0000091 xref: NCIT:C77660 xref: SCTID:95936004 xref: UMLS:C0687080 {source="ncithesaurus:Paw"} is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 ! limb segment intersection_of: has_skeleton UBERON:0006717 ! autopodial skeleton relationship: contributes_to_morphology_of UBERON:0002101 ! limb relationship: develops_from UBERON:0010130 {evidence="definitional"} ! embryonic autopod plate relationship: distally_connected_to UBERON:0002471 ! zeugopod relationship: has_skeleton UBERON:0006717 ! autopodial skeleton property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group; note that this refers to the limb segment, not just the skeleton." xsd:string [Term] id: UBERON:0002471 name: zeugopod namespace: uberon def: "The middle free limb segment, between the autopod and stylopod segments. Includes as parts the zeugopodial skeleton. Examples: There are two types of zeugopod: forelimb zeugopod (aka forearm), hindlimb zeugopod (aka crus)." [https://github.com/obophenotype/uberon/issues/101, PHENOSCAPE:curators] comment: There exists some controversy about which podial segments are present in some fishes, e.g. if the autopod is not newly evolved in tetrapods, there is a question as to which segments are actually present in basal vertebrate taxa.[PHENOSCAPE:curators] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "epipodium" EXACT [MA:th] synonym: "middle free limb segment" EXACT [FMA:83016] synonym: "middle limb segment" EXACT [] synonym: "middle part of limb" BROAD [] synonym: "middle segment of free limb" RELATED [FMA:83016] synonym: "zeugopod limb segment" EXACT [MA:th] synonym: "zeugopodial limb segment" EXACT [MA:th] synonym: "zeugopodium" EXACT [] synonym: "zygopod" EXACT [] synonym: "zygopodium" EXACT [] xref: EFO:0000878 xref: FMA:83016 xref: MA:0002716 xref: MAT:0000092 xref: MIAA:0000092 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 ! limb segment intersection_of: has_skeleton UBERON:0011584 ! zeugopodial skeleton relationship: distal_to UBERON:0002472 ! stylopod relationship: has_skeleton UBERON:0011584 ! zeugopodial skeleton relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: proximal_to UBERON:0002470 ! autopod region property_value: UBPROP:0000007 "zeugopodial" xsd:string [Term] id: UBERON:0002472 name: stylopod namespace: uberon def: "The proximal free limb segment. Includes as parts the stylopod skeleton." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: uberon_slim synonym: "propodium" EXACT [MA:th] synonym: "proximal free limb segment" EXACT [FMA:83014] synonym: "proximal part of limb" BROAD [] synonym: "proximal segment of free limb" RELATED [FMA:83014] synonym: "stylopodial limb segment" EXACT [MA:th] synonym: "stylopodium" EXACT [] xref: EFO:0000879 xref: FMA:83014 xref: MA:0002717 xref: MAT:0000093 xref: MIAA:0000093 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 ! limb segment intersection_of: has_skeleton UBERON:0011583 ! stylopodial skeleton relationship: has_skeleton UBERON:0011583 ! stylopodial skeleton relationship: proximal_to UBERON:0002471 ! zeugopod property_value: RO:0002171 UBERON:0002470 property_value: RO:0002171 UBERON:0002471 property_value: UBPROP:0000007 "stylopodial" xsd:string property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group" xsd:string [Term] id: UBERON:0002481 name: bone tissue namespace: uberon def: "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000047] subset: pheno_slim subset: uberon_slim synonym: "bone" RELATED [MESH:A02.835.232] synonym: "calcium tissue" EXACT [] synonym: "mineralized bone tissue" NARROW [XAO:0004040] synonym: "osseous tissue" EXACT [] synonym: "osteogenic tissue" EXACT [VSAO:curator] synonym: "portion of bone tissue" RELATED [FMA:224804] xref: CALOHA:TS-2011 xref: EMAPA:35179 xref: FMA:224804 xref: galen:BoneTissue xref: MA:0002780 xref: MESH:D001842 xref: NCIT:C13076 xref: UMLS:C0391978 {source="ncithesaurus:Bone_Tissue"} xref: VSAO:0000047 xref: Wikipedia:Bone_tissue xref: XAO:0004040 xref: ZFA:0005621 is_a: UBERON:0004755 {source="VSAO"} ! skeletal tissue disjoint_from: UBERON:0005090 ! muscle structure relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0001474 ! bone element property_value: editor_note "see https://github.com/obophenotype/uberon/issues/27" xsd:string property_value: UBPROP:0000001 "Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000047", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} [Term] id: UBERON:0002488 name: helix of outer ear namespace: uberon def: "The helix is the prominent rim of the pinna." [Wikipedia:Helix] subset: pheno_slim subset: uberon_slim synonym: "helical part of pinna" EXACT [] synonym: "helix" EXACT [MA:0002793] synonym: "helix (auricula)" EXACT [] synonym: "helix of auricle of ear" EXACT [] synonym: "helix of ear" EXACT [] synonym: "helix of pinna" EXACT [] xref: FMA:60992 xref: MA:0002793 xref: NCIT:C32724 xref: SCTID:279607004 xref: UMLS:C0229304 {source="ncithesaurus:Helix"} xref: Wikipedia:Helix_(ear) is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001444 ! subdivision of head relationship: develops_from UBERON:0016611 {source="Wikipedia-uncited"} ! auditory hillocks, pharyngeal arch 1 derived relationship: part_of UBERON:0001757 ! pinna [Term] id: UBERON:0002490 name: frontal suture namespace: uberon def: "A suture that connects the two frontal bones of the skull." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim synonym: "frontal suture of skull" EXACT [] synonym: "median frontal suture" EXACT [] synonym: "metopic suture" RELATED [MA:0002796] synonym: "sutura frontalis" EXACT [Wikipedia:Frontal_suture] synonym: "sutura frontalis" RELATED LATIN [Wikipedia:Frontal_suture] synonym: "sutura metopica" EXACT LATIN [FMA:52989, FMA:TA] xref: EMAPA:19226 xref: EMAPA:35358 xref: FMA:52989 xref: MA:0002796 xref: SCTID:136854008 xref: Wikipedia:Frontal_suture is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0000209 {cardinality="2"} ! tetrapod frontal bone relationship: connects UBERON:0000209 {notes="two halves of the frontal bone"} ! tetrapod frontal bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/17/Gray134.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/d1/Frontal_suture.png" xsd:anyURI property_value: UBPROP:0000008 "in humans, the frontal suture is a dense connective tissue structure that divides the two halves of the frontal bone of the skull in infants and children. It usually disappears by the age of six, with the two halves of the frontal bone being fused together. If it does not disappear it may be called a 'metopic suture' or 'sutura frontalis persistens. ' If the suture is not present at birth (craniosynostosis) it will cause a keel-shaped deformity of the skull called 'trigonocephaly. ' It is present in a fetal skull so that the skull can bend and is very elastic at the time of birth. The baby's head literally bends when coming out of the mother's womb. The space is filled as the child grows older. [WP,unvetted]" xsd:string [Term] id: UBERON:0002495 name: long bone namespace: uberon def: "A long bone is a bone that has a shaft and 2 ends and is longer than it is wide. Long bones have a thick outside layer of compact bone and an inner medullary cavity containing bone marrow. The ends of a long bone contain spongy bone and an epiphyseal plate or line depending on the stage of development. The epiphyseal plate is a hyaline cartilage, where new bone growth takes place, lengthening the bone prior to adulthood. Bone lengthening ceases when this cartilage is lost, leaving a remnant referred to as an epiphyseal line." [https://medlineplus.gov/ency/imagepages/9582.htm, Wikipedia:Long_bone] {seeAlso="https://github.com/obophenotype/uberon/issues/32", seeAlso="https://github.com/obophenotype/uberon/issues/2010"} comment: Endochondral_ossification is an essential process during the rudimentary formation of long bones, with the exception of the clavicle[Wikipedia:Endochondral_ossification]. The medial and and lateral ends undergo EO, the mid-portion is formed by a process with features of EO & IO (the process is shared by the mandible)[ISBN:9780397517251] subset: pheno_slim subset: uberon_slim synonym: "os longum" RELATED [BTO:0004256] xref: BTO:0004256 xref: EMAPA:35503 xref: FMA:7474 xref: galen:LongBone xref: MA:0002802 xref: NCIT:C33003 xref: SCTID:332709000 xref: UMLS:C0222647 {source="ncithesaurus:Long_Bone"} xref: Wikipedia:Long_bone is_a: UBERON:0001474 ! bone element relationship: contributes_to_morphology_of UBERON:0002091 ! appendicular skeleton relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul relationship: part_of UBERON:0002091 ! appendicular skeleton [Term] id: UBERON:0002497 name: acromion namespace: uberon def: "Region of the scapula where the latter meets with the clavicle: attachment point of the clavicle to the scapula in some taxa." [VSAO:0005067] subset: pheno_slim subset: uberon_slim synonym: "acromion of scapula" RELATED [Wikipedia:Acromion] synonym: "acromion of the scapula" RELATED [Wikipedia:Acromion] synonym: "acromion process" EXACT [VSAO:0005067] synonym: "scapular acromion" EXACT [VSAO:0005067] xref: AAO:0000826 xref: EMAPA:25119 xref: FMA:23260 xref: GAID:187 xref: MA:0002805 xref: MESH:D000174 xref: NCIT:C32048 xref: SCTID:181911000 xref: UMLS:C0001209 {source="ncithesaurus:Acromion"} xref: VSAO:0005067 xref: Wikipedia:Acromion is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0006849 ! scapula property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/79/Gray206.png" xsd:anyURI property_value: UBPROP:0000001 "Anterior rounded projection of the pars acromialis of the scapula.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000826", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: part_of pars acromialis (AAO:0000752)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000826", ontology="AAO"} [Term] id: UBERON:0002498 name: deltopectoral crest namespace: uberon def: "A rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches." [ISBN:0-683-40008-8, MP:0004353] subset: pheno_slim subset: uberon_slim synonym: "crista ventralis" EXACT [AAO:0000736] synonym: "crista ventralis humeri" RELATED [AAO:0000736] synonym: "deltoid crest" EXACT [AAO:0000736, MP:0004353] synonym: "deltoid eminence" EXACT [MP:0004353] synonym: "deltoid impression" EXACT [MP:0004353] synonym: "deltoid process" RELATED [MP:0004353] synonym: "deltoid tuberosity" EXACT [FMA:23418] synonym: "deltoid tuberosity of humerus" EXACT [FMA:23418] synonym: "pectoral process" RELATED [] synonym: "tuberositas deltoidea" EXACT LATIN [FMA:23418, FMA:TA] synonym: "tuberositas deltoidea (corpus humeri)" EXACT [] synonym: "tuberositas deltoidea humeri" EXACT LATIN [Wikipedia:Deltoid_tuberosity] xref: AAO:0000736 xref: EMAPA:25052 xref: FMA:23418 xref: MA:0002808 xref: Wikipedia:Deltoid_tuberosity is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005813 ! tubercle is_a: UBERON:4100000 ! skeletal element projection relationship: contributes_to_morphology_of UBERON:0000976 ! humerus relationship: part_of UBERON:0004652 ! humerus diaphysis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a7/HumerusFront.png" xsd:anyURI property_value: UBPROP:0000008 "In basal Tetrapodomorph lineages often the deltoid process and the pectoral processes are separate and thus should not be made exact synonyms to the deltopectoral crest.[PHENOSCAPE:ad]" xsd:string [Term] id: UBERON:0002500 name: zygomatic arch namespace: uberon def: "The bony arch in vertebrates that extends along the side or front of the skull beneath the eye socket and is formed by the temporal process of the zygomatic bone and the zygomatic process of the temporal bone." [ISBN:0-683-40008-8, MP:0004469] subset: pheno_slim subset: uberon_slim synonym: "arcus zygomaticus" RELATED LATIN [Wikipedia:Zygomatic_arch] synonym: "zygoma" EXACT [] xref: EMAPA:36570 xref: FMA:53120 xref: galen:Zygoma xref: MA:0002810 xref: MESH:D015050 xref: MFMO:0000108 xref: NCIT:C33897 xref: SCTID:272682006 xref: UMLS:C0162485 {source="ncithesaurus:Zygomatic_Arch"} xref: Wikipedia:Zygomatic_arch is_a: UBERON:0003462 ! facial bone is_a: UBERON:0011164 {source="MA"} ! neurocranium bone is_a: UBERON:0015212 ! lateral structure relationship: in_lateral_side_of UBERON:0011156 {source="FMA-abduced-lr"} ! facial skeleton property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/f/f4/Gray188-Sphenozygomatic_suture.png" xsd:anyURI property_value: UBPROP:0000008 "The zygomatic arch is significant in evolutionary biology, as it is part of the structures derived from the ancestral single temporal fenestra of the synapsid ancestor of mammals." xsd:string property_value: UBPROP:0000010 "The zygomatic process of the temporal arises by two roots: an anterior, directed inward in front of the mandibular fossa, where it expands to form the articular tubercle. a posterior, which runs backward above the external acoustic meatus and is continuous with the supramastoid crest. The upper border of the arch gives attachment to the temporal fascia; the lower border and medial surface give origin to the Masseter" xsd:string property_value: UBPROP:0000013 "The zygomatic arch is occasionally referred to as the zygoma, but this term usually refers to the zygomatic bone or occasionally the zygomatic process." xsd:string [Term] id: UBERON:0002503 name: greater trochanter namespace: uberon def: "The greater trochanter (great trochanter) of the femur is a large, irregular, quadrilateral eminence and a part of the skeletal system. It is directed a little lateralward and backward, and, in the adult, is about 1 cm lower than the head. Because the pelvic outlet in the female is larger than in the male, there is a greater distance between the greater trochanters in the female. It has two surfaces and four borders. [WP,unvetted]." [Wikipedia:Greater_trochanter] subset: uberon_slim synonym: "great trochanter" EXACT [] synonym: "greater trochanter of femur" EXACT [] synonym: "trochanter major" RELATED LATIN [Wikipedia:Greater_trochanter] xref: EMAPA:37594 {source="MA:th"} xref: FMA:32852 xref: galen:GreaterTrochanter xref: MA:0002822 xref: NCIT:C32698 xref: SCTID:182050001 xref: UMLS:C0223865 {source="ncithesaurus:Great_Trochanter"} xref: Wikipedia:Greater_trochanter is_a: UBERON:0000980 ! trochanter relationship: part_of UBERON:0004412 {source="FMA"} ! proximal epiphysis of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray243.png" xsd:anyURI [Term] id: UBERON:0002504 name: lesser trochanter namespace: uberon def: "The lesser trochanter (small trochanter) of the femur is a conical eminence, which varies in size in different subjects [WP,unvetted]." [Wikipedia:Lesser_trochanter] subset: pheno_slim subset: uberon_slim synonym: "lesser trochanter of femur" EXACT [] synonym: "trochanter minor" RELATED LATIN [Wikipedia:Lesser_trochanter] xref: EMAPA:37595 {source="MA:th"} xref: FMA:32853 xref: galen:LesserTrochanter xref: MA:0002823 xref: NCIT:C32982 xref: SCTID:182051002 xref: UMLS:C0223866 {source="ncithesaurus:Lesser_Trochanter"} xref: Wikipedia:Lesser_trochanter is_a: UBERON:0000980 ! trochanter relationship: part_of UBERON:0004412 {source="FMA"} ! proximal epiphysis of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray341.png" xsd:anyURI [Term] id: UBERON:0002506 name: iris epithelium namespace: uberon def: "An epithelium that is part of a iris [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "epithelial tissue of iris" EXACT [OBOL:automatic] synonym: "epithelium of iris" EXACT [OBOL:automatic] synonym: "epithelium pigmentosum (iris)" EXACT [FMA:58517] synonym: "epithelium pigmentosum iridis" EXACT LATIN [FMA:58517, FMA:TA] synonym: "iris epithelial tissue" EXACT [OBOL:automatic] synonym: "iris epithelium" EXACT [FMA:58517] synonym: "iris pigmented epithelium" RELATED [MA:0002826] synonym: "pigmented epithelium of iris" EXACT [FMA:58517] xref: EMAPA:35447 xref: FMA:58517 xref: MA:0002826 is_a: UBERON:0000488 {source="FMA"} ! atypical epithelium is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001769 ! iris relationship: contributes_to_morphology_of UBERON:0001769 ! iris relationship: has_part GO:0048770 {source="MP"} ! pigment granule relationship: part_of UBERON:0001769 {source="MA"} ! iris property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002511 name: trabecula carnea namespace: uberon def: "The supporting bundles of muscular fibers lining the walls of the ventricles of the heart." [MGI:monikat, MP:0004067] subset: pheno_slim synonym: "cardiac trabecula" RELATED [GO:0060347] synonym: "columnae carneae" RELATED LATIN [Wikipedia:Trabeculae_carneae] synonym: "heart trabecula" RELATED [GO:0060347] synonym: "trabecula of heart" RELATED [] synonym: "trabeculae carneae" RELATED PLURAL [] synonym: "trabeculae carneae cordis" RELATED LATIN [Wikipedia:Trabeculae_carneae] synonym: "ventricle trabecula carnea" EXACT [MA:0002831] synonym: "ventricular trabecula" RELATED [MA:0002831] xref: EMAPA:18626 xref: FMA:7269 xref: MA:0002831 xref: SCTID:118755002 xref: Wikipedia:Trabeculae_carneae is_a: UBERON:0000440 ! trabecula is_a: UBERON:0004120 ! mesoderm-derived structure relationship: composed_primarily_of UBERON:0001133 ! cardiac muscle tissue relationship: part_of UBERON:0002082 {source="WP"} ! cardiac ventricle property_value: UBPROP:0000009 "The purpose of the trabeculae carneae is most likely to prevent suction that would occur with a flat surfaced membrane and thus impair the heart's ability to pump efficiently. The trabeculae carneae also serve a similar function to papillary muscles in that their contraction pulls on the chordae tendineae, preventing inversion of the mitral (bicuspid) and tricuspid valves, that is, their bulging towards the atrial chambers, which would lead to subsequent leakage of the blood into the atria. So by the action of papillary muscles on the atrioventricular valves, backflow of the blood from the ventricles into the atria is prevented" xsd:string {source="WP"} property_value: UBPROP:0000012 "Note that WP states they are ventricular, but MP has classes for atrial ventricular carnea." xsd:string {external_ontology="MP"} [Term] id: UBERON:0002513 name: endochondral bone namespace: uberon def: "Replacement bone that forms within cartilage." [GO:0001958, GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/54, VSAO:0000145] subset: uberon_slim subset: vertebrate_core synonym: "cartilaginous bone" RELATED [BTO:0002157] synonym: "endochondral bones" RELATED PLURAL [ZFA:0001591] synonym: "ossified chondrogenic bone" EXACT [VSAO:0000145] xref: AAO:0010776 xref: AEO:0000083 xref: BTO:0002157 xref: EHDAA2:0003083 xref: FMA:24321 xref: TAO:0001591 xref: VSAO:0000145 xref: XAO:0004018 xref: ZFA:0001591 is_a: UBERON:0001474 ! bone element is_a: UBERON:0010363 {source="VSAO"} ! endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: develops_from UBERON:0005863 ! cartilaginous condensation relationship: developmentally_replaces UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0007844 {source="VSAO"} ! cartilage element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Hypertrophic_Zone_of_Epiphyseal_Plate.jpg" xsd:anyURI property_value: editor_note "placement in this class to be inferred" xsd:string property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern" xsd:anyURI property_value: UBPROP:0000001 "Replacement bone that forms within cartilage.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000145", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} property_value: UBPROP:0000012 "some structures, e.g. in ZFA are both intramembrane and endochondral" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0002514 name: intramembranous bone namespace: uberon def: "Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [GO:0001957, https://github.com/obophenotype/uberon/issues/267, Wikipedia:Intramembranous_ossification] synonym: "intramembranous bones" RELATED PLURAL [ZFA:0001635] synonym: "membrane bone" RELATED [AEO:0000085] xref: EMAPA:36615 xref: TAO:0001644 xref: Wikipedia:Intramembranous_ossification xref: ZFA:0001635 is_a: UBERON:0001474 {source="VSAO"} ! bone element relationship: develops_from UBERON:0003104 ! mesenchyme relationship: output_of GO:0001957 ! intramembranous ossification property_value: UBPROP:0000001 "Bone that forms directly within mesenchyme, and does not replace other tissues.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001644", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000005 "[In TAO], This term was made obsolete because it is considered a synonym of membrane bone (VSAO:0000023).[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0001644", ontology="TAO", source="Curator"} [Term] id: UBERON:0002517 name: basicranium namespace: uberon def: "The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof." [Wikipedia:Base_of_skull] comment: The skull base is formed from a series of cartilages either side of, and rostral to, the notochord, whose tip lies just caudal to the pituitary gland. It is closely associated with the sensory capsules, which partially or completely sur- round the olfactory epithelium, the eye, and the inner ear[PMID:11523816] subset: pheno_slim subset: uberon_slim synonym: "base of cranium" EXACT [] synonym: "base of skull" EXACT [FMA:52801] synonym: "basis cranii" EXACT LATIN [FMA:52801, FMA:TA, Wikipedia:Base_of_skull] synonym: "cranial base" EXACT [FMA:52801, MA:0002840] xref: FMA:52801 xref: MA:0002840 xref: MESH:D019291 xref: MFMO:0000044 xref: NCIT:C12493 xref: SCTID:181890004 xref: UMLS:C0149543 {source="ncithesaurus:Base_of_the_Skull"} xref: Wikipedia:Base_of_skull is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 ! subdivision of skeletal system relationship: contributes_to_morphology_of UBERON:0003128 ! cranium relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png" xsd:anyURI property_value: UBPROP:0000007 "basicranial" xsd:string [Term] id: UBERON:0002521 name: elastic tissue namespace: uberon def: "Connective tissue composed of elastic fibers." [http://orcid.org/0000-0002-6601-2165] subset: uberon_slim synonym: "elastic connective tissue" EXACT [] synonym: "elastic fiber" NARROW [] synonym: "textus connectivus elasticus" EXACT LATIN [] xref: FMA:20113 xref: GAID:926 xref: MA:0002853 xref: MESH:D004547 xref: NCIT:C32495 xref: SCTID:27197004 xref: Wikipedia:Elastic_fiber is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: composed_primarily_of GO:0071953 ! elastic fiber relationship: composed_primarily_of GO:0071953 ! elastic fiber relationship: has_quality PATO:0001171 ! elastic property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/cb/Gray377.png" xsd:anyURI [Term] id: UBERON:0002522 name: tunica media namespace: uberon def: "The middle layer of an artery or vein. [WP,unvetted]." [Wikipedia:Tunica_media] comment: May be composed of smooth muscle and elastic tissue subset: uberon_slim synonym: "tunica media vasorum" RELATED LATIN [BTO:0002011, Wikipedia:Tunica_media] xref: BTO:0002011 xref: EMAPA:36298 xref: FMA:55590 xref: GAID:170 xref: MA:0002855 xref: MESH:D017540 xref: NCIT:C33821 xref: SCTID:61695000 xref: UMLS:C0162867 {source="ncithesaurus:Tunica_Media"} xref: Wikipedia:Tunica_media is_a: UBERON:0004797 {source="MA"} ! blood vessel layer relationship: has_part UBERON:0002521 {source="cjm"} ! elastic tissue relationship: has_part UBERON:0004237 {source="cjm"} ! blood vessel smooth muscle relationship: surrounded_by UBERON:0005734 ! tunica adventitia of blood vessel property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI [Term] id: UBERON:0002523 name: tunica intima namespace: uberon def: "The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]." [ISBN:0073040584, NCIT:C33820, Wikipedia:Tunica_intima] subset: uberon_slim synonym: "Bichat's tunic" RELATED [BTO:0002012] synonym: "intima" RELATED [BTO:0002012] synonym: "tunica intima vasorum" RELATED [BTO:0002012] xref: BTO:0002012 xref: EMAPA:36297 xref: FMA:55589 xref: GAID:523 xref: MA:0002861 xref: MESH:D017539 xref: NCIT:C33820 xref: SCTID:8361002 xref: SCTID:87483006 xref: UMLS:C0162864 {source="ncithesaurus:Tunica_Intima"} xref: Wikipedia:Tunica_intima is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 {source="FMA"} ! organ component layer relationship: adjacent_to UBERON:0010161 {source="ISBN:0073040584"} ! lumen of blood vessel relationship: has_part UBERON:0001986 ! endothelium relationship: surrounded_by UBERON:0002522 {notes="check for exceptions, e.g. capillaries"} ! tunica media property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI property_value: editor_note "the FMA class represents a more generic layer which is the superclass of the layer found in both blood vessels and lymph vessels (and also endocardium) - we should probably follow this structure" xsd:string property_value: editor_note "the FMA class represents a structure which may have both epithelium and fibroelastic connective tissue as parts" xsd:string property_value: UBPROP:0000001 "The tunica intima (or just intima) is the innermost layer of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow. The inner coat (tunica intima) can be separated from the middle by a little maceration, or it may be stripped off in small pieces; but, on account of its friability, it cannot be separated as a complete membrane. It is a fine, transparent, colorless structure which is highly elastic, and, after death, is commonly corrugated into longitudinal wrinkles. The inner coat consists of: A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round or oval nuclei. This endothelium is brought into view most distinctly by staining with silver nitrate. A subendothelial layer, consisting of delicate connective tissue with branched cells lying in the interspaces of the tissue; in arteries of less than 2 mm. in diameter the subendothelial layer consists of a single stratum of stellate cells, and the connective tissue is only largely developed in vessels of a considerable size. An elastic or fenestrated layer, which consists of a membrane containing a net-work of elastic fibers, having principally a longitudinal direction, and in which, under the microscope, small elongated apertures or perforations may be seen, giving it a fenestrated appearance. It was therefore called by Henle the fenestrated membrane. This membrane forms the chief thickness of the inner coat, and can be separated into several layers, some of which present the appearance of a network of longitudinal elastic fibers, and others a more membranous character, marked by pale lines having a longitudinal direction. In minute arteries the fenestrated membrane is a very thin layer; but in the larger arteries, and especially in the aorta, it has a very considerable thickness. [WP,unvetted].[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Tunica_intima"} [Term] id: UBERON:0002529 name: limb segment namespace: uberon def: "A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles." [https://orcid.org/0000-0002-6601-2165] synonym: "extremity part" RELATED [] synonym: "free limb segment" EXACT [FMA:241863] synonym: "limb region" RELATED [] synonym: "region of limb" RELATED [] synonym: "segment of limb" EXACT [] synonym: "subdivision of limb" EXACT [] xref: FMA:241863 xref: MA:0002889 xref: NCIT:C38630 xref: UMLS:C1268195 {source="ncithesaurus:Extremity_Part"} is_a: UBERON:0010538 ! paired limb/fin segment intersection_of: UBERON:0010758 ! subdivision of organism along appendicular axis intersection_of: part_of UBERON:0002101 ! limb disjoint_from: UBERON:0010912 ! subdivision of skeleton relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: existence_starts_during UBERON:0000068 ! embryo stage relationship: has_part UBERON:0014892 ! skeletal muscle organ relationship: part_of UBERON:0002101 ! limb property_value: editor_note "TODO - align this with the CARO2 class 'appendage segment'; note the FMA class does not appear to require repetition" xsd:string property_value: UBPROP:0000012 "FMA has both limb segment and free limb segment, the former includes the girdles. Note that MA uses the term more generally and includes A,S,Z,S+Z(arm/leg), whereas FMA is just A,S,Z" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0002530 name: gland namespace: uberon def: "An organ that functions as a secretory or excretory organ." [MGI:csmith, MP:0002163] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "Druese" RELATED [BTO:0000522] synonym: "glandula" RELATED LATIN [BTO:0000522, Wikipedia:Gland] synonym: "glandular organ" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000212 xref: AEO:0000096 xref: BTO:0000522 xref: EFO:0000797 xref: EHDAA2:0003096 xref: EHDAA:2161 xref: EHDAA:4475 xref: EHDAA:6522 xref: EMAPA:18425 xref: FBbt:00100317 xref: FMA:7146 xref: FMA:86294 xref: galen:Gland xref: HAO:0000375 xref: MA:0003038 xref: MAT:0000021 xref: MIAA:0000021 xref: NCIT:C13319 xref: SCTID:134358001 xref: UMLS:C1285092 {source="ncithesaurus:Gland"} xref: Wikipedia:Gland xref: WikipediaCategory:Glands is_a: UBERON:0000062 ! organ relationship: capable_of GO:0046903 ! secretion relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: produces UBERON:0000463 ! organism substance property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a1/Gray1026.png" xsd:anyURI property_value: RO:0002171 UBERON:0001434 property_value: UBPROP:0000007 "glandular" xsd:string [Term] id: UBERON:0002532 name: epiblast (generic) namespace: uberon def: "In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]." [Wikipedia:Epiblast, ZFIN:curator] subset: early_development subset: grouping_class subset: uberon_slim subset: vertebrate_core synonym: "blastocyst" RELATED [] synonym: "ectoblast" RELATED [MP:0003886] synonym: "epiblast" EXACT [VHOG:0000243] synonym: "epiblastus" RELATED LATIN [Wikipedia:Epiblast] synonym: "primitive ectoderm" RELATED [VHOG:0000243] xref: BTO:0004593 xref: FMA:296704 xref: MAT:0000067 xref: MIAA:0000067 xref: VHOG:0000243 xref: Wikipedia:Epiblast is_a: UBERON:0002050 ! embryonic structure relationship: has_part CL:0000352 ! epiblast cell property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e3/Gray21.png" xsd:anyURI property_value: editor_note "MP says - tissue that gives rise to the ectoderm, endoderm and mesoderm of the embryo proper. In HOG, epiblast is part of primitive streak/blastpore, which is inconsistent with the MP definition of primitive streak as a ridge of the epiblast. Note that these terms, epiblast and hypoblast, are also used to describe layers of the avian embryonic blastoderm, but the layers so-named seem to be altogether different in these two kinds of vertebrate embryos(CVS). Consider obsoleting this as a grouping class" xsd:string property_value: UBPROP:0000003 "In pregastrula zebrafish embryos, the epiblast is an inverted cup of cells that sits on top of a large yolk cell. (...) In amniote embryos (mammals and birds), gastrulation initiates in an epithelial layer called the epiblast. Cells in the epiblast undergo an epithelial to mesenchymal transition (EMT), migrate through the primitive streak (PS), and incorporate in the middle (mesoderm) or outer (endoderm) layer. The presumptive definitive endoderm (DE) cells invade and displace an outer layer of extraembryonic tissue cells, the hypoblast in chick and the visceral endoderm (VE) in mouse, which form supporting structures such as the yolk sac.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000243", ontology="VHOG", source="DOI:10.1146/annurev.cellbio.042308.113344 Zorn AM, Wells JM, Vertebrate endoderm development and organ formation. Annual Review of Cell Developmental Biology (2009)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002533 name: post-anal tail bud namespace: uberon def: "The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node." [BTO:0001445] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "end bud" RELATED [BTO:0001445] synonym: "tail bud" EXACT [ZFA:0000077] synonym: "tail bud mesenchyme" RELATED [ZFA:0000077] synonym: "tailbud" EXACT [] xref: AAO:0011104 xref: BTO:0001445 xref: EFO:0002748 xref: EHDAA2:0001976 xref: EHDAA:1595 xref: EMAPA:16580 xref: MAT:0000070 xref: MIAA:0000070 xref: TAO:0000077 xref: VHOG:0000201 xref: XAO:0000107 xref: ZFA:0000077 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0007812 ! post-anal tail relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: editor_note "See notes from https://github.com/obophenotype/uberon/wiki/The-neural-crest" xsd:string property_value: UBPROP:0000001 "Rapidly proliferating mass of cells at the caudal extremity of the embryo. Its formation is reflected in a caudal carving of the posterior portion of the archenteric canal at NF stage 22. With its further outgrowth, the postanal gut primordium becomes stretched. Its lumen is in broad communication with the hindgut at NF stage 25.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011104", ontology="AAO", source="ISBN:0815318960", source="OMD:tail+bud"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (5) a larva or embryo with a postanal tail.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000201", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0002536 name: arthropod sensillum namespace: uberon def: "Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]." [FBbt:00007152, Wikipedia:Sensillum] subset: efo_slim subset: uberon_slim synonym: "sensillum" EXACT [FBbt:00007152, HAO:0000933] xref: BTO:0001237 xref: EFO:0000939 xref: FBbt:00007152 xref: HAO:0000933 xref: MAT:0000163 xref: MIAA:0000163 xref: TGMA:0000540 xref: Wikipedia:Sensillum is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000020 ! sense organ relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda relationship: part_of UBERON:0001016 ! nervous system property_value: editor_note "this term should be ceded to the arthropod anatomy ontology" xsd:string [Term] id: UBERON:0002537 name: hermaphrodite gonad namespace: uberon def: "A gonad with both testicular and ovarian aspects[WP]." [Wikipedia:Ovotestis] subset: efo_slim synonym: "glandula hermaphroditica" NARROW SENSU [Wikipedia:Ovotestis#In_gastropods] synonym: "hermaphrodite genitalia" EXACT [GO:0040035] synonym: "hermaphrodite gland" NARROW SENSU [Wikipedia:Ovotestis#In_gastropods] synonym: "ovotestis" RELATED [BTO:0000981] xref: BTO:0000981 xref: EFO:0000971 xref: MAT:0000165 xref: MIAA:0000165 xref: WBbt:0005178 xref: Wikipedia:Ovotestis is_a: UBERON:0000991 ! gonad intersection_of: UBERON:0000991 ! gonad intersection_of: capable_of GO:0007283 ! spermatogenesis intersection_of: capable_of GO:0048477 ! oogenesis relationship: capable_of GO:0007283 ! spermatogenesis relationship: capable_of GO:0048477 ! oogenesis relationship: part_of UBERON:0007197 ! hermaphroditic organism [Term] id: UBERON:0002539 name: pharyngeal arch namespace: uberon def: "One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches." [http://orcid.org/0000-0002-6601-2165, PMID:16313389, ZFA:yb] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "arcus pharyngei" RELATED LATIN [Wikipedia:Pharyngeal_arch] synonym: "branchial arch" NARROW [BTO:0001785, MP:0002884] synonym: "pharyngeal arches" EXACT PLURAL [] synonym: "visceral arch" RELATED [] xref: AAO:0010359 xref: BTO:0001785 xref: EFO:0000959 xref: EHDAA:571 xref: EMAPA:16117 xref: FMA:293015 xref: GAID:1292 xref: MAT:0000242 xref: MESH:D001934 xref: MIAA:0000242 xref: NCIT:C34249 xref: SCTID:308766004 xref: TAO:0001306 xref: UMLS:C0080322 {source="ncithesaurus:Pharyngeal_Arch"} xref: VHOG:0000155 xref: Wikipedia:Pharyngeal_arch xref: XAO:0000096 xref: ZFA:0001306 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: developmentally_induced_by UBERON:0007690 {source="PMID:16313389"} ! early pharyngeal endoderm relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0008814 ! pharyngeal arch system relationship: part_of UBERON:0008816 {source="PMID:16313389"} ! embryonic head property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png" xsd:anyURI property_value: UBPROP:0000001 "One of a series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010359", ontology="AAO", source="NLM:branchial+arch"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000155", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "Numbered cranial to caudal. different in mammals. branchial arch = ZFA:0001613 pharyngeal arch 3-7. generally gill arch 1 = pharyngeal arch 3. terminology varies as to whether branchial arch follows gill or pharyngeal numbering" xsd:string [Term] id: UBERON:0002544 name: digit namespace: uberon def: "A subdivision of the autopod that has as part a series of phalanges together with associated vasculature, musculature, integument and nerves. It is continuous with the metapodial subdivision of the autopod, but does not include the metapodials. In species such as humans, fully formed digits are distinct, whereas in other species the digits may be connected by interdigital webbing, or may be completely unseparated (for example, in cetaceans)." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/420] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "acropodial unit" EXACT [] synonym: "digit (phalangeal portion) plus soft tissue" EXACT COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "limb digit" EXACT [MA:0000690] xref: AAO:0011126 xref: EFO:0000881 xref: EMAPA:32725 xref: FMA:85518 {notes="GAT"} xref: galen:Digit xref: MA:0000690 xref: MAT:0000285 xref: MIAA:0000285 xref: NCIT:C40186 xref: SCTID:361367007 xref: UMLS:C0582802 {source="ncithesaurus:Digit"} xref: VHOG:0000944 xref: Wikipedia:Digit_(anatomy) xref: XAO:0003032 is_a: UBERON:0005881 ! autopodial extension intersection_of: UBERON:0005881 ! autopodial extension intersection_of: part_of UBERON:0012354 ! acropodium region relationship: contributes_to_morphology_of UBERON:0002470 ! autopod region relationship: has_part UBERON:0015023 ! phalanx endochondral element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/balhoff relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of UBERON:0012354 ! acropodium region relationship: part_of UBERON:5002544 ! digit plus metapodial segment property_value: IAO:0000232 "this class represents the entire organism subdivision encompassing soft tissue as well as the underlying skeletal framework. The class represents the phalangeal part only - historically the term 'digit' has also been used to represent the unit consisting of a series of phalanges together with a metapodial bone. We may in future relabel this class to avoid confusion with this concept, but the class will continue to represent the phalangeal portion" xsd:string property_value: RO:0002171 UBERON:0009877 property_value: UBPROP:0000003 "Our reinterpretation of the distal fin endoskeleton of Panderichthys removes the final piece of evidence supporting the formerly popular hypothesis that tetrapod digits are wholly new structures without homologues in sarcopterygian fish fins. This hypothesis, which was based partly on the complete absence of plausible digit homologues in Panderichthys (then the closest known relative of tetrapods), has already been called into question by the discovery of digit-like radials in Tiktaalik and the fact that Hox gene expression patterns closely resembling those associated with digit formation in tetrapods occur in the distal fin skeletons of paddlefish and Australian lungfish. Our new data show that Panderichthys is not an anomaly: like Tiktaalik and other fish members of the Tetrapodomorpha, it has distal radials that can be interpreted as digit homologues.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000944", ontology="VHOG", source="DOI:10.1038/nature07339 Boisvert CA, Mark-Kurik E and Ahlberg PE, The pectoral fin of Panderichthys and the origin of digits. Nature (2008)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "digital" xsd:string [Term] id: UBERON:0002546 name: cranial placode namespace: uberon def: "Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic." [http://www.ncbi.nlm.nih.gov/books/NBK53175/, https://github.com/obophenotype/uberon/issues/135, https://github.com/seger/aao/issues/4, https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/p/obo/xenopus-anatomy-xao-term-requests/11/] subset: efo_slim synonym: "cranial placodes" RELATED PLURAL [XAO:0000305] synonym: "ectodermal cranial placode" EXACT [UBERON:cjm] synonym: "ectodermal placode" BROAD INCONSISTENT [FMA:293966, PMID:22512454] synonym: "placode" BROAD [Wikipedia:Placode] xref: AAO:0010466 xref: EFO:0001650 xref: FMA:293966 xref: MAT:0000369 xref: MIAA:0000369 xref: XAO:0000305 is_a: UBERON:0005085 {source="cjm"} ! ectodermal placode relationship: only_in_taxon NCBITaxon:7711 {source="PMID:11523831", source="PMID:22512454"} ! Chordata relationship: part_of UBERON:0000033 ! head property_value: editor_note "Do not merge with neurogenic placode" xsd:string property_value: UBPROP:0000008 "Comparisons of developmental gene expression suggest that the anterior ectoderm in amphioxus may be homologous to the vertebrate olfactory placode, the only vertebrate placode with primary, not secondary, neurons" xsd:string {source="PMID:11523831"} property_value: UBPROP:0000013 "The term placode or placodes also applies to developing organs such as teeth, mammary glands, hair follicles, feathers and scales. We include a separate parent class for this. to avoid confusion, we include neurogenic placode as a subclass" xsd:string [Term] id: UBERON:0002548 name: larva namespace: uberon def: "A distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle." [Wikipedia:Larva] subset: uberon_slim synonym: "ammocoete" NARROW [Wikipedia:Larva] synonym: "bipinnaria" NARROW [Wikipedia:Larva] synonym: "caterpillar" NARROW [Wikipedia:Larva] synonym: "glochidium" NARROW [Wikipedia:Larva] synonym: "grub" NARROW [Wikipedia:Larva] synonym: "larval organism" EXACT [TAO:0002048] synonym: "leptocephalus" NARROW [Wikipedia:Larva] synonym: "maggot" NARROW [Wikipedia:Larva] synonym: "naiad" NARROW [Wikipedia:Larva] synonym: "nymph" NARROW [Wikipedia:Larva] synonym: "planula" NARROW [Wikipedia:Larva] synonym: "tadpole" NARROW [Wikipedia:Larva] synonym: "trochophore" NARROW [Wikipedia:Larva] synonym: "veliger" NARROW [Wikipedia:Larva] synonym: "wriggler" NARROW [Wikipedia:Larva] synonym: "zoea" NARROW [Wikipedia:Larva] xref: AEO:0000126 xref: BTO:0000707 xref: FBbt:00001727 xref: HAO:0000459 xref: MESH:D007814 xref: TAO:0002048 xref: Wikipedia:Larva is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_and_ends_during UBERON:0000069 ! larval stage relationship: existence_starts_and_ends_during UBERON:0000069 ! larval stage relationship: has_quality PATO:0001185 ! larval property_value: editor_note "TODO discriminate between stages and organisms" xsd:string property_value: UBPROP:0000001 "Whole organism that is premetamorphic or a very immature individual.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002048", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000007 "larval" xsd:string [Term] id: UBERON:0002553 name: anatomical cavity namespace: uberon def: "Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina." [FMA:67552] subset: upper_level synonym: "cavity" BROAD [] xref: BIRNLEX:1011 xref: EMAPA:37442 {source="MA:th"} xref: FMA:67552 xref: galen:Cavity xref: MA:0002447 xref: NCIT:C34007 is_a: UBERON:0000464 ! anatomical space relationship: location_of UBERON:0000463 ! organism substance [Term] id: UBERON:0002558 name: organ cavity namespace: uberon subset: upper_level synonym: "cavity of organ" EXACT [FMA:12237] xref: BIRNLEX:1019 xref: FMA:12237 xref: SCTID:362606005 is_a: UBERON:0002553 ! anatomical cavity [Term] id: UBERON:0002561 name: lumen of central nervous system namespace: uberon def: "The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube." [https://orcid.org/0000-0002-6601-2165] synonym: "cavity of neuraxis" EXACT [FMA:75007] synonym: "cavity of ventricular system of neuraxis" EXACT [FMA:75007] synonym: "neuraxis cavity" EXACT [FMA:75007] synonym: "neuraxis lumen" EXACT [] xref: BIRNLEX:1029 xref: FMA:75007 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002558 ! organ cavity intersection_of: UBERON:0002558 ! organ cavity intersection_of: luminal_space_of UBERON:0001017 ! central nervous system relationship: develops_from UBERON:0003842 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="cjm"} ! neural tube lumen relationship: luminal_space_of UBERON:0001017 ! central nervous system relationship: part_of UBERON:0001017 ! central nervous system property_value: RO:0002175 NCBITaxon:569425 {source="DOI:10.1186/s12983-014-0089-2"} [Term] id: UBERON:0002616 name: regional part of brain namespace: uberon def: "Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia." [BIRNLEX:1167] subset: non_informative synonym: "anatomical structure of brain" EXACT [OBOL:automatic] synonym: "biological structure of brain" EXACT [OBOL:automatic] synonym: "brain anatomical structure" EXACT [OBOL:automatic] synonym: "brain biological structure" EXACT [OBOL:automatic] synonym: "brain part" EXACT [] synonym: "neuraxis segment" EXACT [FMA:55676] synonym: "neuroanatomical region" EXACT [] synonym: "segment of brain" EXACT [BIRNLEX:1167] xref: BIRNLEX:1167 xref: FMA:55676 xref: NCIT:C13031 xref: SCTID:384763002 xref: UMLS:C0445620 {source="ncithesaurus:Brain_Part"} is_a: UBERON:0000073 ! regional part of nervous system is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: part_of UBERON:0000955 ! brain relationship: composed_primarily_of UBERON:0003714 ! neural tissue relationship: part_of UBERON:0000955 ! brain [Term] id: UBERON:0002726 name: cervical spinal cord namespace: uberon def: "A spinal cord segment that adjacent_to a cervical region." [OBOL:automatic] subset: human_reference_atlas synonym: "cervical segment of spinal cord" EXACT [FMA:71166] synonym: "cervical segments of spinal cord [1-8]" EXACT [FMA:71166] synonym: "cervical spinal cord" EXACT [FMA:71166] synonym: "pars cervicalis medullae spinalis" EXACT LATIN [FMA:71166, FMA:TA] synonym: "segmenta cervicalia medullae spinalis [1-8" EXACT LATIN [FMA:71166, FMA:TA] xref: BIRNLEX:1499 xref: FMA:71166 xref: MA:0003081 xref: NCIT:C12892 xref: neuronames:1654 xref: SCTID:180960003 xref: UMLS:C0581619 {source="BIRNLEX:1499", source="ncithesaurus:Cervical_Spinal_Cord"} xref: UMLS:C1278837 {source="BIRNLEX:1499"} is_a: UBERON:0005844 ! spinal cord segment intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: adjacent_to UBERON:0005434 ! cervical region relationship: adjacent_to UBERON:0005434 ! cervical region relationship: only_in_taxon NCBITaxon:8287 ! Sarcopterygii property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002792 name: lumbar spinal cord namespace: uberon subset: human_reference_atlas subset: uberon_slim synonym: "lumbar segment of spinal cord" EXACT [FMA:71168] synonym: "lumbar segments of spinal cord [1-5]" EXACT [FMA:71168] synonym: "lumbar spinal cord" EXACT [FMA:71168] synonym: "pars lumbalis medullae spinalis" EXACT LATIN [FMA:71168, FMA:TA] synonym: "segmenta lumbalia medullae spinalis [1-5]" EXACT LATIN [FMA:71168, FMA:TA] synonym: "spinal cord lumbar segment" EXACT [MA:0003083] xref: BIRNLEX:1704 xref: FMA:71168 xref: MA:0003083 xref: NCIT:C12895 xref: neuronames:1677 xref: SCTID:180962006 xref: UMLS:C0581620 {source="BIRNLEX:1704"} xref: UMLS:C0581621 {source="ncithesaurus:Lumbar_Spinal_Cord"} xref: UMLS:C1278838 {source="BIRNLEX:1704"} xref: Wikipedia:Lumbar_spinal_cord is_a: UBERON:0005844 ! spinal cord segment intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: part_of UBERON:0005462 ! lower back relationship: part_of UBERON:0005462 ! lower back property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0002812 name: left cerebral hemisphere namespace: uberon def: "A cerebral hemisphere that is in the left side of a brain." [OBOL:automatic] synonym: "left hemisphere" EXACT [BIRNLEX:1795] xref: BIRNLEX:1795 xref: FMA:61819 xref: NCIT:C32955 xref: SCTID:362323007 xref: UMLS:C0228176 {source="ncithesaurus:Left_Cerebral_Hemisphere"} is_a: UBERON:0001869 ! cerebral hemisphere intersection_of: UBERON:0001869 ! cerebral hemisphere intersection_of: in_left_side_of UBERON:0000955 ! brain relationship: in_left_side_of UBERON:0000955 ! brain property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0002813 name: right cerebral hemisphere namespace: uberon def: "A cerebral hemisphere that is in the right side of a brain." [OBOL:automatic] synonym: "right hemisphere" EXACT [BIRNLEX:1797] xref: BIRNLEX:1797 xref: FMA:67292 xref: NCIT:C33472 xref: SCTID:362322002 xref: UMLS:C0228175 {source="ncithesaurus:Right_Cerebral_Hemisphere"} is_a: UBERON:0001869 ! cerebral hemisphere intersection_of: UBERON:0001869 ! cerebral hemisphere intersection_of: in_right_side_of UBERON:0000955 ! brain relationship: in_right_side_of UBERON:0000955 ! brain property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0002871 name: hypoglossal nucleus namespace: uberon def: "Nucleus forming a longitudinal cell column in the medulla, close beneath the floor of the 4th ventricle, containing motor neurons that innervate the muscles of the tongue (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 453)." [BIRNLEX:2644] subset: pheno_slim subset: uberon_slim synonym: "hypoglossal nerve nucleus" EXACT [FMA:54505] synonym: "hypoglossal nucleus" EXACT [FMA:54505] synonym: "hypoglossal XII nucleus" EXACT [MA:0001039] synonym: "nucleus hypoglossalis" RELATED LATIN [NeuroNames:757] synonym: "nucleus nervi hypoglossi" EXACT LATIN [FMA:54505, FMA:TA] synonym: "nucleus nervi hypoglossi" RELATED LATIN [Wikipedia:Hypoglossal_nucleus] synonym: "nucleus of hypoglossal nerve" EXACT [FMA:54505] synonym: "twelfth cranial nerve nucleus" EXACT [FMA:54505] xref: BAMS:12 xref: BAMS:12N xref: BAMS:XII xref: BIRNLEX:2644 xref: BM:XII xref: DHBA:12545 xref: EHDAA2:0004635 xref: EMAPA:35416 xref: EV:0100286 xref: FMA:54505 xref: HBA:9557 xref: MA:0001039 xref: MBA:773 xref: NCIT:C12899 xref: ncithesaurus:Nucleus_of_the_Hypoglossal_Nerve xref: neuronames:757 {source="BIRNLEX:2644"} xref: SCTID:47361005 xref: UMLS:C0228802 {source="BIRNLEX:2644", source="ncithesaurus:Hypoglossal_Nucleus"} xref: VHOG:0001358 xref: Wikipedia:Hypoglossal_nucleus is_a: UBERON:0000126 ! cranial nerve nucleus is_a: UBERON:0007635 ! nucleus of medulla oblongata intersection_of: UBERON:0000126 ! cranial nerve nucleus intersection_of: extends_fibers_into UBERON:0001650 ! hypoglossal nerve relationship: extends_fibers_into UBERON:0001650 ! hypoglossal nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png" xsd:anyURI property_value: RO:0002171 UBERON:0001719 {source="ABA"} property_value: RO:0002171 UBERON:0002127 {source="ABA"} property_value: RO:0002171 UBERON:0002154 {source="ABA"} property_value: RO:0002171 UBERON:0002155 {source="ABA"} property_value: RO:0002171 UBERON:0002559 {source="ABA"} property_value: RO:0002171 UBERON:0002673 {source="ABA"} property_value: RO:0002171 UBERON:0002870 {source="ABA"} property_value: RO:0002171 UBERON:0002872 {source="ABA"} property_value: RO:0002171 UBERON:0002877 {source="ABA"} [Term] id: UBERON:0002925 name: trigeminal nucleus namespace: uberon def: "A nucleus of brain that is part of a trigeminal nuclear complex." [OBOL:automatic] subset: uberon_slim synonym: "nucleus mesencephalicus nervi trigemini" RELATED [BTO:0001074] synonym: "nucleus mesencephalicus trigeminalis" RELATED [BTO:0001074] synonym: "nucleus of trigeminal nuclear complex" EXACT [FMA:71247] synonym: "nucleus tractus mesencephali nervi trigeminalis" RELATED [BTO:0001074] synonym: "trigeminal nuclear complex nucleus" EXACT [FMA:71247] synonym: "trigeminal nucleus" EXACT [FMA:71248] synonym: "trigeminal V nucleus" EXACT [MA:0001028] xref: BM:V xref: BTO:0001074 xref: CALOHA:TS-2077 xref: EMAPA:35883 xref: EV:0100271 xref: FMA:71247 xref: GAID:604 xref: http://uri.neuinfo.org/nif/nifstd/nifext_11 xref: MA:0001028 xref: MESH:D014278 xref: NCIT:C12807 xref: SCTID:280164007 xref: UMLS:C0040999 {source="ncithesaurus:Trigeminal_Nucleus"} xref: VHOG:0001353 is_a: UBERON:0000126 ! cranial nerve nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0007641 ! trigeminal nuclear complex relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve relationship: part_of UBERON:0007641 ! trigeminal nuclear complex property_value: UBPROP:0000012 "massive inconsistencies between GO, MA, wikipedia. Part of pons in MA, but this leads to inconsistencies with ABA." xsd:string {external_ontology="GO", url="https://github.com/obophenotype/mouse-anatomy-ontology/issues/58"} [Term] id: UBERON:0002926 name: gustatory epithelium namespace: uberon def: "A sensory epithelium that is part of a gustatory system." [OBOL:automatic] xref: FMA:62412 xref: http://uri.neuinfo.org/nif/nifstd/nifext_12 is_a: UBERON:0006934 ! sensory epithelium intersection_of: UBERON:0006934 ! sensory epithelium intersection_of: part_of UBERON:0001033 ! gustatory system relationship: part_of UBERON:0000012 {source="NIFSTD"} ! somatic nervous system relationship: part_of UBERON:0001033 ! gustatory system relationship: part_of UBERON:0001723 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! tongue [Term] id: UBERON:0003023 name: pontine tegmentum namespace: uberon def: "Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133)." [BIRNLEX:923] subset: human_reference_atlas subset: uberon_slim synonym: "dorsal pons" EXACT [] synonym: "dorsal portion of pons" EXACT [FMA:71108] synonym: "pars dorsalis pontis" RELATED LATIN [NeuroNames:557] synonym: "pars posterior pontis" RELATED LATIN [NeuroNames:557] synonym: "tegmental portion of pons" EXACT [FMA:71108] synonym: "tegmentum of pons" EXACT [FMA:71108] synonym: "tegmentum pontis" EXACT LATIN [FMA:71108, FMA:TA] synonym: "tegmentum pontis" RELATED LATIN [Wikipedia:Pontine_tegmentum] xref: BAMS:PTg xref: BIRNLEX:923 xref: DHBA:12416 xref: FMA:71108 xref: HBA:9135 xref: MESH:D065821 xref: neuronames:557 {source="BIRNLEX:923"} xref: SCTID:362401009 xref: UMLS:C0228426 {source="BIRNLEX:923"} xref: Wikipedia:Pontine_tegmentum is_a: UBERON:0000064 ! organ part is_a: UBERON:0004121 ! ectoderm-derived structure relationship: has_part UBERON:0002047 ! pontine raphe nucleus relationship: has_part UBERON:0002128 ! superior olivary complex relationship: has_part UBERON:0002148 ! locus ceruleus relationship: has_part UBERON:0002149 ! superior salivatory nucleus relationship: part_of UBERON:0000988 ! pons property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/9c/Brainstem_Abducens.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000009 "involved in the initiation of REM sleep [Wikipedia:Pontine_tegmentum]" xsd:string [Term] id: UBERON:0003037 name: septum namespace: uberon def: "A wall, dividing a cavity or structure into smaller ones[WP]." [Wikipedia:Septum] comment: general anatomical term in FMA subset: pheno_slim synonym: "septa" EXACT PLURAL [] xref: AAO:0011127 xref: FMA:86461 xref: Wikipedia:Septum is_a: UBERON:0000061 ! anatomical structure relationship: located_in UBERON:0002553 ! anatomical cavity property_value: UBPROP:0000007 "septal" xsd:string [Term] id: UBERON:0003038 name: thoracic spinal cord namespace: uberon def: "The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]." [Wikipedia:Thoracic_spinal_cord] subset: human_reference_atlas subset: uberon_slim synonym: "pars thoracica medullae spinalis" EXACT LATIN [FMA:71167, FMA:TA] synonym: "segmenta thoracica medullae spinalis [1-12]" EXACT LATIN [FMA:71167, FMA:TA] synonym: "thoracic region of spinal cord" EXACT [FMA:71167] synonym: "thoracic segment of spinal cord" EXACT [FMA:71167] synonym: "thoracic segments of spinal cord [1-12]" EXACT [FMA:71167] synonym: "thoracic spinal cord" EXACT [FMA:71167] xref: BIRNLEX:966 xref: FMA:71167 xref: MA:0003082 xref: NCIT:C12894 xref: neuronames:1718 xref: SCTID:278750009 xref: UMLS:C0581620 {source="ncithesaurus:Thoracic_Spinal_Cord", source="BIRNLEX:966"} xref: Wikipedia:Thoracic_spinal_cord is_a: UBERON:0005844 ! spinal cord segment intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0008231 ! dorsal thoracic segment of trunk property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/68/Gray820.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003041 name: trigeminal nerve fibers namespace: uberon def: "A nerve fiber that is part of a trigeminal nerve." [OBOL:automatic] synonym: "central part of trigeminal nerve" EXACT [FMA:72501] synonym: "fibrae nervi trigemini" RELATED LATIN [NeuroNames:607] synonym: "trigeminal nerve fibers" EXACT [FMA:72501] synonym: "trigeminal nerve tract" EXACT [FMA:72501] xref: BAMS:5nf xref: BIRNLEX:974 xref: FMA:72501 xref: neuronames:607 {source="BIRNLEX:974"} xref: UMLS:C0175452 {source="BIRNLEX:974"} is_a: UBERON:0006134 ! nerve fiber intersection_of: UBERON:0006134 ! nerve fiber intersection_of: part_of UBERON:0001645 ! trigeminal nerve relationship: part_of UBERON:0001645 ! trigeminal nerve [Term] id: UBERON:0003050 name: olfactory placode namespace: uberon def: "A thick plate of cells derived from the neural ectoderm in the head region of the embryo that develops into the olfactory region of the nasal cavity." [Wikipedia:Nasal_placode, XAO:0000005] comment: Olfactory placodes are the only ectodermal placodes to produce glia, a cell type typically derived from neural crest // Note that NBK53171 classifies this as non-neurogenic subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "nasal I placode" RELATED [] synonym: "nasal placode" RELATED [] synonym: "olfactory placodes" EXACT PLURAL [] synonym: "placoda nasalis" EXACT LATIN [] synonym: "placoda olfactoria" EXACT LATIN [] xref: AAO:0011076 xref: EFO:0003420 xref: EHDAA2:0001232 xref: EHDAA:1504 xref: EMAPA:16543 xref: FMA:293971 xref: TAO:0000048 xref: VHOG:0000186 xref: Wikipedia:Nasal_placode xref: XAO:0000005 xref: ZFA:0000048 is_a: UBERON:0009955 {contradicted_by="NCBIBook:NBK53171", source="ZFA"} ! neurogenic placode relationship: develops_from UBERON:0002346 ! neurectoderm relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (2) neurogenic placodes (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000186", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003051 name: ear vesicle namespace: uberon alt_id: UBERON:0004373 def: "An epithelial sac of invaginated ectoderm formed from the otic placode that gives rise to the structures of the inner ear[MP]." [MP:0009806, Wikipedia:Otic_vesicle] subset: pheno_slim subset: vertebrate_core synonym: "acoustic vesicle" RELATED [VHOG:0001148] synonym: "auditory vesicle" RELATED [BTO:0002661] synonym: "otic vesicle" EXACT [MP:0004311] synonym: "otocyst" RELATED [MP:0004311] synonym: "OV" RELATED [] xref: AAO:0011080 xref: BTO:0002661 xref: EHDAA2:0001342 xref: EMAPA:16669 xref: FMA:302920 xref: NCIT:C34240 xref: SCTID:308792006 xref: TAO:0000051 xref: UMLS:C1518678 {source="ncithesaurus:Otic_Vesicle"} xref: VHOG:0001148 xref: Wikipedia:Otic_vesicle xref: XAO:0000006 xref: ZFA:0000051 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0007499 ! epithelial sac is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0007499 ! epithelial sac intersection_of: has_potential_to_develop_into UBERON:0001846 ! internal ear intersection_of: part_of UBERON:0000924 ! ectoderm relationship: develops_from UBERON:0006273 ! otic pit relationship: has_potential_to_develop_into UBERON:0001846 ! internal ear relationship: part_of UBERON:0000924 ! ectoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray40.png" xsd:anyURI property_value: UBPROP:0000001 "Epithelial sac present beside the fifth rhombomere; forms the semicircular canals dorsally and the otolith organs ventrally, and houses the acoustico-vestibular sensory epithelia (maculae) of hair cells. Kimmel et al, 1995. (Also see Anatomical Atlas entry for ear by T. Whitfield.)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000051", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "One of the paired sacs of invaginated ectoderm that develop into the membranous labyrinth of the internal ear. [Biology_online][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001148", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The inner ear develops embryonically in all vertebrates as an invagination of the ectodermal otic placode to form an otic vesicle.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001148", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.413", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "MP defines as epithelial sac, but EHDAA defines as multi-tissue; See https://github.com/obophenotype/uberon/issues/1305" xsd:string {external_ontology="MP"} [Term] id: UBERON:0003052 name: midbrain-hindbrain boundary namespace: uberon def: "The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate." [GO:0021555] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "isthmic organizer territory" RELATED [XAO:0000016] synonym: "isthmo-cerebellar region" RELATED [VHOG:0000649] synonym: "isthmus" RELATED [] synonym: "isthmus/MHB" RELATED [Geisha:syn, NCBITaxon:8782] synonym: "MHB" EXACT [] synonym: "mid-hindbrain boundary" EXACT [] synonym: "mid-hindbrain junction" EXACT [] synonym: "midbrain hindbrain boundary" EXACT [] xref: AAO:0011064 xref: DMBA:16810 xref: EHDAA2:0004395 xref: EHDAA:5789 xref: EMAPA:32857 xref: NCIT:C93172 xref: neuronames:2076 xref: TAO:0000042 xref: VHOG:0000649 xref: XAO:0000016 xref: ZFA:0000042 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007651 {inconsistent_with="ZFA", source="https://sourceforge.net/p/obo/zebrafish-anatomy-zfa-term-requests/106/"} ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: overlaps UBERON:0001891 ! midbrain intersection_of: overlaps UBERON:0002028 ! hindbrain relationship: develops_from UBERON:0009615 ! midbrain hindbrain boundary neural plate relationship: immediate_transformation_of UBERON:0009615 {source="ZFA"} ! midbrain hindbrain boundary neural plate relationship: overlaps UBERON:0001891 ! midbrain relationship: overlaps UBERON:0002028 ! hindbrain relationship: part_of UBERON:0000955 {source="ZFA"} ! brain property_value: editor_note "consider adding class for organizer. Consider adding separate class for isthmus as a structure" xsd:string property_value: UBPROP:0000003 "Lampreys also have an MHB [midbrain hindbrain boundary], expressing a similar repertoire of regulatory gene cognates as in gnathostomes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000649", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.02.008 Murakami Y, Uchida K, Rijli FM and Kuratani S, Evolution of the brain developmental plan: Insights from agnathans. Developmental Biology (2005)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003055 name: periderm namespace: uberon def: "A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis." [ISBN:9780878932504] subset: pheno_slim subset: uberon_slim synonym: "epidermis epithelial layer" RELATED [] synonym: "epidermis outer layer" RELATED [] synonym: "epitrichium" RELATED [MP:0013530] synonym: "EVL" RELATED [ZFA:0001185] synonym: "periderm" RELATED [] synonym: "skin periderm" EXACT [EHDAA2:0001846] xref: EHDAA2:0001846 xref: EHDAA:6538 xref: FMA:295662 xref: NCIT:C34247 xref: TAO:0001185 xref: UMLS:C1518973 {source="ncithesaurus:Periderm"} xref: VHOG:0001680 xref: XAO:0000029 xref: ZFA:0001185 is_a: UBERON:0000487 {source="EHDAA2"} ! simple squamous epithelium is_a: UBERON:0010371 ! ecto-epithelium relationship: develops_from UBERON:0007383 {source="ZFA"} ! enveloping layer of ectoderm relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument property_value: UBPROP:0000001 "The outermost epidermal layer covering the fish at embryonic stages; derived from the EVL and thought to eventually be replaced by the superficial stratum of the epidermis. Sometimes used synonymously with EVL. Le Guellec et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001185", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship type change: OBO_REL:part_of ectoderm (TAO:0000016) CHANGED TO: develops_from ectoderm (UBERON:0000924)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001185", ontology="TAO"} property_value: UBPROP:0000008 "In mice, the first non-basal layer formed at ~E9.5; it is a temporary structure composed of simple squamous epithelium that serves as the first barrier to the embryo's physical environment, exists throughout the entire keratinocyte stratification process, and sheds off at ~E17, when it is replaced by corneocytes[MP]" xsd:string property_value: UBPROP:0000011 "In some mammals, Eyelid Fusion is thought to be driven by a population of cells which are derived from the periderm, the outermost layer of the developing epidermis" xsd:string property_value: UBPROP:0000011 "Originally the epidermis is one layer thick, in most vertebrates it soon becomes a two-layered structure. The outer layer gives rise to the periderm. The periderm goes through distinct developmental phases and is ultimately sloughed into the amniotic fluid when differentiation of the underlying epidermal layers is complete. The function of the periderm is not known, but is thought to be related to transport/exchange between the fetus and the amniotic fluid (http://courses.washington.edu/hubio567/devbio/periderm.html)" xsd:string [Term] id: UBERON:0003056 name: pre-chordal neural plate namespace: uberon def: "The portion of neural plate anterior to the mid-hindbrain junction." [XB:curator] synonym: "anterior neural plate" RELATED [] xref: AAO:0011084 xref: TAO:0007016 xref: VHOG:0001200 xref: XAO:0000045 xref: ZFA:0007016 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: anterior_to UBERON:0009615 ! midbrain hindbrain boundary neural plate relationship: part_of UBERON:0003075 ! neural plate property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001200", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003057 name: chordal neural plate namespace: uberon def: "The portion of neural plate posterior to the mid-hindbrain junction." [XB:curator] synonym: "posterior neural plate" RELATED [] xref: TAO:0007017 xref: VHOG:0001201 xref: XAO:0000046 xref: ZFA:0007017 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0003075 ! neural plate relationship: posterior_to UBERON:0009615 ! midbrain hindbrain boundary neural plate property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001201", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003059 name: presomitic mesoderm namespace: uberon def: "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form." [ZFIN:curator] subset: efo_slim subset: pheno_slim synonym: "presumptive somite mesoderm" RELATED [] synonym: "PSM" RELATED [] synonym: "segmental plate" EXACT [] synonym: "somitogenic mesoderm" RELATED [] synonym: "somitomeric mesoderm" RELATED [GO:0002075] synonym: "unsegmented mesenchyme" RELATED [VHOG:0000559] synonym: "unsegmented paraxial mesoderm" EXACT [https://orcid.org/0000-0002-6601-2165] xref: AAO:0011086 xref: EFO:0001982 xref: EMAPA:16189 xref: EMAPA:16752 xref: TAO:0000279 xref: VHOG:0000559 xref: XAO:0000057 xref: ZFA:0000279 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: has_potential_to_develop_into UBERON:0002329 ! somite intersection_of: immediate_transformation_of UBERON:0007282 ! presumptive segmental plate relationship: develops_from UBERON:0007282 ! presumptive segmental plate relationship: has_potential_to_develop_into UBERON:0002329 ! somite relationship: immediate_transformation_of UBERON:0007282 {source="Bgee:AN"} ! presumptive segmental plate relationship: part_of UBERON:0003077 ! paraxial mesoderm property_value: UBPROP:0000001 "Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000279", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "It is reasonable to assume that the proximate invertebrate ancestor of the vertebrates had an amphioxus-like tail bud in its larval stage. This archetypal tail bud would have (...) (3) lacked any component of mesenchyme cells, (4) budded off new mesodermal segments directly, without any intervening zone of presomitic mesoderm (...). Then, early in vertebrate evolution, epithelium-to-mesenchyme interconversions (and the gene networks for effecting them) became prominent features of development. (...) In any case, conspicuous mesenchymal components tended to be added to the vertebrate tail bud itself. In addition, a mesenchymatous presomitic mesoderm (not a part of the tail bud proper) came to intervene between the tail bud and the forming somites.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000559", ontology="VHOG", source="DOI:10.1006/dbio.2001.0460 Schubert M, Holland LZ, Dale Stokes M and Holland ND, Three Amphoxius Wnt Genes (AmphiWnt3, AmphiWnt5, and AmphiWnt6) Associated with the Tail Bud: the Evolution of Somitogenesis in Chordates. Developmental Biology (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003060 name: pronephric duct namespace: uberon def: "In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]." [Wikipedia:Pronephric_duct] comment: The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney[GOC:mtg_kidney_jan10, PMID:15647339, XAO:0000063, ZFA:0000150] subset: uberon_slim synonym: "archinephric duct" RELATED [VHOG:0000082] synonym: "ductus pronephricus" RELATED LATIN [Wikipedia:Pronephric_duct] synonym: "pronephric ducts" RELATED PLURAL [ZFA:0000150] xref: AAO:0011088 xref: NCIT:C34279 xref: SCTID:361406002 xref: TAO:0000150 xref: UMLS:C1283945 {source="ncithesaurus:Pronephric_Duct"} xref: VHOG:0000082 xref: Wikipedia:Pronephric_duct xref: XAO:0000063 xref: ZFA:0000150 is_a: UBERON:0009201 {source="GO"} ! nephric duct is_a: UBERON:0012275 ! meso-epithelium relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm relationship: develops_from UBERON:0005721 {source="XAO"} ! pronephric mesoderm relationship: part_of UBERON:0002120 ! pronephros property_value: UBPROP:0000001 "Duct of the embryonic kidney, present bilaterally ventral to the somites and leading to the anal region where it empties separately from, and just posterior to the anus. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000150", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "(...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003061 name: blood island namespace: uberon def: "Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]." [Wikipedia:Blood_island_of_umbilical_vesicle] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "blood islands" EXACT PLURAL [] synonym: "caudal hematopoietic tissue" RELATED [] synonym: "posterior blood island" RELATED [] synonym: "posterior ICM" RELATED [] synonym: "VBI" RELATED [] synonym: "ventral blood island" RELATED [] synonym: "ventral lateral plate mesoderm" BROAD [] xref: AAO:0011006 xref: EFO:0003489 xref: EHDAA:207 xref: NCIT:C34113 xref: TAO:0000094 xref: TE:E5.11.2.0.0.0.4 xref: UMLS:C1511224 {source="ncithesaurus:Blood_Island"} xref: VHOG:0000085 xref: Wikipedia:Blood_island_of_umbilical_vesicle xref: XAO:0000067 xref: ZFA:0000094 is_a: UBERON:0006598 ! presumptive structure relationship: develops_from UBERON:0003081 ! lateral plate mesoderm relationship: has_potential_to_develop_into UBERON:0002390 ! hematopoietic system property_value: UBPROP:0000001 "Nests of developing blood cells arising late in the segmentation period from the intermediate mass, and located in the anterior-ventral tail, just posterior to the yolk extension. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000094", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Region located on the ventral surface of the developing embryo that is a site of hematopoiesis and that is analogous to the yolk sac blood islands of higher vertebrates.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011006", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000002 "relationship loss: part_of intermediate cell mass of mesoderm (TAO:0000033)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000094", ontology="TAO"} property_value: UBPROP:0000003 "Small clusters of mesodermal cells called blood islands mark the embryonic debut of the cardiovascular system (in vertebrates) (reference 1); In birds and mammals, primitive hemangioblasts are extraembryonic, populating the yolk sac as the so-called blood islands (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000085", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.450, DOI:10.1146/annurev.cellbio.22.010605.093317 Hartenstein V, Blood cells and blood cell development in the animal kingdom. Annual Review of Cell and Developmental Biology (2006)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "EHDAA2 distinguishes 3 types, but does not have a superclass. The VHOG class may refer to yolk sac" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0003063 name: prechordal plate namespace: uberon alt_id: UBERON:0004881 def: "A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue." [ISBN:0838580343, MP:0004387] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "head mesenchyme" BROAD [XAO:0000079] synonym: "head mesoderm" BROAD [XAO:0000079] xref: AAO:0011085 xref: EHDAA2:0001493 xref: EHDAA:181 xref: FMA:295532 xref: TAO:0000060 xref: VHOG:0000086 xref: Wikipedia:Prechordal_plate xref: XAO:0000079 xref: ZFA:0000060 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0034878 ! prechordal mesoderm relationship: part_of UBERON:0003068 {source="ZFA"} ! axial mesoderm relationship: transformation_of UBERON:0034878 {todo="PMID:16313393"} ! prechordal mesoderm property_value: editor_note "TODO - check; developmental relationship to anterior hypoblast in ZFA?" xsd:string property_value: UBPROP:0000001 "Axial hypoblast located anterior to the chorda mesoderm; the polster is its most anterior region. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000060", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Axial mesoderm that lies anterior to the notochord and that underlies the forebrain. [Amphioxus_goosecoid_and_the_evolution_of_the_head_organizer_and_prechordal_plate._Evolution_and_Development_(2008)_2(6):303-310, Neidert_AH, Panopoulou_G_and_Langeland_JA][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000086", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "There are two opposing models that can potentially explain the differences in gsc (goosecoid) expression between amphioxus and vertebrates. In one model, the vertebrate gsc expression pattern more closely resembles the common ancestral state and the amphioxus gsc expression pattern is a derivation associated with its unique morphology. (...) In an alternate model, the amphioxus gsc expression pattern most closely represents the common ancestral state and the vertebrate pattern is derived. This model suggests that the evolution of vertebrates was accompanied by the segregation of gsc expression, from a more general domain underlying the entire brain anlage to a distinct forebrain organizer domain and subsequent prechordal plate. We feel this second model is more parsimonious than the first model in that what would be novel anterior gsc expression in vertebrates directly correlates with a novel vertebrate anterior structure, the prechordal plate.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000086", ontology="VHOG", source="DOI:10.1046/j.1525-142x.2000.00073.x Neidert AH, Panopoulou G and Langeland JA, Amphioxus goosecoid and the evolution of the head organizer and prechordal plate. Evolution and Development (2008)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003064 name: intermediate mesoderm namespace: uberon def: "The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." [GOC:curators, Wikipedia:Intermediate_mesoderm] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "IM" RELATED [] synonym: "intermediate mesenchyme" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "intermediate plate" RELATED [EMAPA:16178] synonym: "intermediate plate mesoderm" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "mesenchyma intermedium" RELATED LATIN [Wikipedia:Intermediate_mesoderm] xref: AAO:0010575 xref: EMAPA:16056 xref: EMAPA:16178 xref: FMA:293147 xref: NCIT:C34193 xref: SCTID:361476001 xref: TAO:0001206 xref: UMLS:C1284010 {source="ncithesaurus:Intermediate_Mesoderm"} xref: VHOG:0000087 xref: Wikipedia:Intermediate_mesoderm xref: XAO:0000085 xref: ZFA:0001206 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: adjacent_to UBERON:0003077 ! paraxial mesoderm relationship: adjacent_to UBERON:0003081 ! lateral plate mesoderm relationship: develops_from UBERON:0000926 {source="XAO"} ! mesoderm relationship: part_of UBERON:0000926 {source="AAO"} ! mesoderm relationship: part_of UBERON:0005256 {source="EMAPA"} ! trunk mesenchyme property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: UBPROP:0000001 "Mesoderm between somite and lateral plate. Traditionally thought to give rise to the urogenital system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010575", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "(...)the mesoderm of a developing vertebrate transitionally differentiates into the following sub-types: Chordamesoderm (also known as axial mesoderm) which later on gives rise to notochord in all chordates, Paraxial mesoderm, Intermediate mesoderm, Lateral plate mesoderm (reference 1); The mesoderm is present in Bilateria, therefore they are sometimes called triploblasts. Ectoderm and endoderm are usually organized as epithelial layers, while mesoderm can be epithelial or a compact, three-dimensional tissue.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000087", ontology="VHOG", source="Wikipedia:Mesoderm, ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.43", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "all AOs differ in the relationship between this structure and the mesoderm; in ZFA it is a subclass (and this is implied by the GO definition and GO relationships), in AAO it is part of, and in EHDAA2 it develops from the mesoderm (but in EHDAA2 the naming convention is to use 'paraxial mesenchyme', rather than 'paraxial mesoderm')." xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0003066 name: pharyngeal arch 2 namespace: uberon def: "The second pharyngeal arch will form the hyoid apparatus. The cranial neural crest cells that populate the second pharyngeal arch emerge primarily from rhombomere 4 and will form skeletal elements." [https://github.com/obophenotype/uberon/issues/258, PMID:12784288, ZFIN:yb] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "2nd arch" RELATED [EHDAA2:0000050] synonym: "2nd pharyngeal arch" EXACT [] synonym: "2nd visceral arch" RELATED [VHOG:0000297] synonym: "arcus pharyngeus secundus" EXACT LATIN [Wikipedia:Second_pharyngeal_arch] synonym: "branchial arch 2" EXACT SENSU [] synonym: "hyoid arch" EXACT [XAO:0000098] synonym: "hyoid bars" RELATED [] synonym: "pharyngeal arch 2" EXACT [] synonym: "pharyngeal arches 2" RELATED [VHOG:0000297] synonym: "second branchial arch" EXACT SENSU [] synonym: "second pharyngeal arch" EXACT [] synonym: "second visceral arch" EXACT SENSU [] synonym: "visceral arch 2" EXACT SENSU [] xref: AAO:0010363 xref: EHDAA2:0000050 xref: EHDAA:611 xref: EMAPA:16272 xref: FMA:293017 xref: NCIT:C34288 xref: SCTID:308768003 xref: TAO:0001596 xref: VHOG:0000297 xref: Wikipedia:Second_pharyngeal_arch xref: XAO:0000098 xref: ZFA:0001611 is_a: UBERON:0002539 ! pharyngeal arch property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8b/Gray41.png" xsd:anyURI property_value: UBPROP:0000001 "The second of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010363", ontology="AAO", source="XAO:EJS"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000297", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in XAO, develops from visceral pouch 2" xsd:string {external_ontology="XAO"} property_value: UBPROP:0000103 "2" xsd:nonNegativeInteger [Term] id: UBERON:0003067 name: dorsolateral placode namespace: uberon def: "Lateral neurogenic placodes positioned dorsal of the epibranchial placodes." [ZFIN:curator] comment: The only remaining dorsolateral placode in land vertebrates is the otic/octaval placode synonym: "dorsolateral placodes" EXACT PLURAL [ZFA:0001310] xref: TAO:0001310 xref: VHOG:0000103 xref: XAO:0000187 xref: ZFA:0001310 is_a: UBERON:0009955 {source="NCBIBook:NBK53175"} ! neurogenic placode relationship: dorsal_to UBERON:0003078 ! epibranchial placode property_value: UBPROP:0000003 "In summary, the collective term 'placodes' refers to some rather different structures, probably with different evolutionary origins. Some sensory placodes (at least the otic and olfactory) may have homologues in basal chordates. Even if this is so, it is apparent that they were elaborated considerably during early vertebrate evolution. Epibranchial and dorsolateral placodes appear to be new; we infer that their origin depended on the evolution of specific inductive signals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000103", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003068 name: axial mesoderm namespace: uberon def: "The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." [GO:0048318, Wikipedia:Chordamesoderm] subset: efo_slim subset: uberon_slim synonym: "chordamesoderm" RELATED [Wikipedia:Chordamesoderm] xref: AAO:0011017 xref: EFO:0003647 xref: TAO:0001204 xref: VHOG:0000107 xref: Wikipedia:Chordamesoderm xref: XAO:0000205 xref: ZFA:0001204 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0000926 ! mesoderm relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0000926 ! mesoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: UBPROP:0000001 "The portion of the mesoderm underlying the midline of the embryo. [Gastrulation:_From_cells_to_embryo_(2004)_Cold_Spring_Harbor, Glossary_XV, New_York:_Cold_Spring_Harbor_Laboratory_Press, Stern_CD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000107", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003069 name: otic placode namespace: uberon def: "A cranial placode which, once specified, invaginates to form an otic cup, which eventually separates from the surface ectoderm to form the otic vesicle or otocyst, a rounded structure without appar- ent polarity. As the otic placode invaginates into a cup neuroblasts delaminate from the anterior ventral aspect of the otic epithelium to give rise to neurons of the vestibulocochlear (statoacoustic) ganglion of cranial nerve VIII[NBK]." [NCBIBook:NBK53175, Wikipedia:Otic_placode] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "auditory placode" RELATED [] synonym: "ear placode" RELATED [] synonym: "ear/otic placode" RELATED [] synonym: "octaval placode" RELATED [ISBN:0471888893] synonym: "octaval VIII placode" RELATED [ISBN:0471888893] synonym: "placoda otica" EXACT LATIN [] xref: AAO:0011079 xref: EFO:0003429 xref: EHDAA2:0001339 xref: EHDAA:506 xref: EMAPA:16195 xref: FMA:293973 xref: NCIT:C34239 xref: TAO:0000138 xref: UMLS:C1518677 {source="ncithesaurus:Otic_Placodes"} xref: VHOG:0000235 xref: Wikipedia:Otic_placode xref: XAO:0000223 xref: ZFA:0000138 is_a: UBERON:0003067 {notes="invaginates", source="NCBIBook:NBK53175"} ! dorsolateral placode relationship: part_of UBERON:0001690 ! ear property_value: UBPROP:0000001 "Primordium of the ear epithelium before it hollows into the otic vesicle, present beside the hindbrain rudiment in the midsegmentation period. Kimmel et al, 1995. (Also see Anatomical Atlas entry for ear by T. Whitfield.)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000138", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (...) (2) neurogenic placodes (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000235", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "With the exception of the pigment cells of the stria vascularis and the secretory epithelium of the cochlea, which are of neural crest origin, all compo- nents of the inner ear derive from the otic placode. In most species the thickening of the ectoderm into a placode occurs in a region adjacent to rhombomere 5 (reviewed in Ohyama et al., 2007), while in amphibians the otic placode is centered onto rhombomere 4 (Ruiz i Altaba and Jessell, 1991)." xsd:string {source="NCBIBook:NBK53175"} [Term] id: UBERON:0003070 name: trigeminal placode complex namespace: uberon def: "A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/693, PMID:22512454] subset: efo_slim synonym: "profundus placode" RELATED INCONSISTENT [ISBN:0471888893] synonym: "profundus V placode" RELATED INCONSISTENT [ISBN:0471888893] synonym: "trigeminal placode" EXACT [EHDAA2:0004209, VHOG:0000109, XAO:0000225, ZFA:0000162] synonym: "trigeminal placodes" RELATED PLURAL [ZFA:0000162] synonym: "trigeminal V placode" EXACT [] xref: EFO:0003433 xref: EHDAA2:0004209 xref: TAO:0000162 xref: VHOG:0000109 xref: XAO:0000225 xref: ZFA:0000162 is_a: UBERON:0003067 {source="ISBN:0471888893"} ! dorsolateral placode relationship: has_potential_to_developmentally_contribute_to UBERON:0003942 ! somatosensory system relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/ANiknejad relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly property_value: UBPROP:0000001 "The ectodermal precursor of the trigeminal ganglion. The profundal and the trigeminal ganglia are separate distally but fused at their proximal end as they condense around NF stage 24.[XAO]" xsd:string {ontology="XAO"} property_value: UBPROP:0000001 "The ectodermal rudiment of the trigeminal ganglion, distinguishable during much of the segmentation period. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000162", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The dorsolateral placodes (trigeminal and vestibular) develop from ectoderm lateral to the brain (...). In summary, the collective term 'placodes' refers to some rather different structures, probably with different evolutionary origins. Some sensory placodes (at least the otic and olfactory) may have homologues in basal chordates. Even if this is so, it is apparent that they were elaborated considerably during early vertebrate evolution. Epibranchial and dorsolateral placodes appear to be new; we infer that their origin depended on the evolution of specific inductive signals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000109", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "Consider naming this 'trigeminal placode complex'. Also, Fig9-5 of ISBN:0471888893 calls this the profundus placode; XAO says 'profundal and the trigeminal ganglia are separate distally but fused at their proximal end...'" xsd:string [Term] id: UBERON:0003071 name: eye primordium namespace: uberon alt_id: UBERON:0005060 def: "Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles." [GO:0046619, ZFA:0000570] subset: efo_slim synonym: "eye anlage" RELATED [XAO:0000227] synonym: "eye field" RELATED [] synonym: "eye placode" EXACT [OBOL:automatic] synonym: "occular primordium" EXACT [] synonym: "ocular primordium" EXACT [] synonym: "optic field" RELATED [] synonym: "optic placode" EXACT [GO:0046619] synonym: "optic placode of camera-type eye" EXACT [GO:0046619, https://orcid.org/0000-0002-6601-2165] synonym: "optic placodes" RELATED PLURAL [] synonym: "optic primordium" EXACT [] xref: AAO:0011038 xref: EFO:0003541 xref: EHDAA2:0004431 xref: TAO:0000570 xref: XAO:0000227 xref: XAO:0004090 xref: ZFA:0000570 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0001048 ! primordium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0000019 ! camera-type eye relationship: develops_from UBERON:0003056 ! pre-chordal neural plate relationship: has_potential_to_develop_into UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0003056 {source="PMID:16496288", source="XAO"} ! pre-chordal neural plate property_value: UBPROP:0000012 "TODO - check that GO's optic placode is the same as ZFA's eye primordium; we may want to have separate term for ocular primordium precursor. XAO has both optic field and eye primordium." xsd:string {external_ontology="GO"} [Term] id: UBERON:0003072 name: optic cup namespace: uberon def: "Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]." [MP:0004269, Wikipedia:Optic_cup_(embryology), ZFA:0001202] subset: pheno_slim subset: vertebrate_core synonym: "eye cup" RELATED [] synonym: "eyecup" RELATED [BTO:0005351] synonym: "ocular cup" RELATED [VHOG:0000167] synonym: "ophtalmic cup" RELATED [BTO:0005351] xref: BTO:0005351 xref: EHDAA2:0001303 xref: EHDAA:2912 xref: EMAPA:16674 xref: NCIT:C34233 xref: SCTID:308789007 xref: TAO:0001202 xref: UMLS:C0231109 {source="ncithesaurus:Optic_Cup"} xref: VHOG:0000167 xref: ZFA:0001202 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: developmentally_induced_by UBERON:0003073 ! lens placode relationship: develops_from UBERON:0004128 {source="ZFA"} ! optic vesicle relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000167", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003073 name: lens placode namespace: uberon def: "A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]." [Wikipedia:Lens_placode, ZFIN:curator] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lens placodes" RELATED PLURAL [ZFA:0000122] synonym: "placoda lentis" RELATED LATIN [Wikipedia:Lens_placode] xref: AAO:0011055 xref: EFO:0003494 xref: EHDAA2:0000982 xref: EHDAA:2908 xref: EMAPA:16672 xref: FMA:296767 xref: NCIT:C34202 xref: TAO:0000122 xref: UMLS:C1517770 {source="ncithesaurus:Lens_Placodes"} xref: VHOG:0000166 xref: Wikipedia:Lens_placode xref: XAO:0000240 xref: ZFA:0000122 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0002546 ! cranial placode is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0010312 ! immature eye is_a: UBERON:0011814 {source="NCBIBook:NBK53175"} ! non-neurogenic ectodermal placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: has_potential_to_develop_into UBERON:0000965 ! lens of camera-type eye relationship: developmentally_induced_by UBERON:0004128 ! optic vesicle relationship: has_potential_to_develop_into UBERON:0000965 ! lens of camera-type eye relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2f/Gray864.png" xsd:anyURI property_value: UBPROP:0000001 "Ectodermal primordium of the lens of the eye. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000122", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000166", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "Classical transplantation experiments using amphibian embryos suggested that the optic vesicle is the source of lens-inducing signals sufficient to generate lens tissues in competent ectoderm (reviewed in Grainger et al., 1996). More recent findings suggest a multistep model for lens induction. There is now good evidence that lens specification occurs at the neurula stage, before the optic vesicle contact the surface ectoderm, and that neural crest cell migration in the frontonasal region is required to restrict the position of the lens placode (Bailey et al., 2006)" xsd:string {source="NCBIBook:NBK53175"} [Term] id: UBERON:0003074 name: mesonephric duct namespace: uberon def: "Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]." [https://github.com/obophenotype/uberon/issues/28, Wikipedia:Mesonephric_duct, ZFIN:curator] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "archinephric duct" RELATED [VHOG:0000082, Wikipedia:Wolffian_duct] synonym: "ductus mesonephricus; ductus Wolffi" RELATED LATIN [Wikipedia:Mesonephric_duct] synonym: "Leydig's duct" RELATED [Wikipedia:Wolffian_duct] synonym: "renal duct" RELATED [] synonym: "Wolffian duct" EXACT [GOC:yaf, Wikipedia:Wolffian_duct, ZFA:0000546] xref: AAO:0000637 xref: EHDAA2:0001243 xref: EHDAA:1590 xref: EMAPA:16577 xref: GAID:1315 xref: MESH:D014928 xref: NCIT:C26469 xref: SCTID:308800003 xref: TAO:0000546 xref: UMLS:C0043204 {source="ncithesaurus:Mesonephric_Duct"} xref: VHOG:0000082 xref: Wikipedia:Mesonephric_duct xref: XAO:0000242 xref: ZFA:0000546 is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0009201 {source="GO"} ! nephric duct relationship: develops_from UBERON:0003060 ! pronephric duct relationship: develops_from UBERON:0005792 {source="EHDAA2"} ! nephric ridge relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/rfoulger property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI property_value: editor_note "Consider adding subclasses for male and female specific variants" xsd:string property_value: editor_note "TODO - mesonephric portion of the nephric duct" xsd:string property_value: UBPROP:0000001 "Anatomical structure consisting of either of a pair of longitudinal ducts which carry urine and in males, sperm, to the cloaca.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000637", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The first-formed kidney duct, which drains the kidney of most anamniotes and becomes the ductus deferens of male amniotes. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-3, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "(...) in all craniates, the archinephric duct develops in embryogeny.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000082", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.686", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "In the male the Wolffian duct persists, and forms for example the epididymis, the ductus deferens, the ejaculatory duct, seminal vesicle and efferent ducts." xsd:string [Term] id: UBERON:0003075 name: neural plate namespace: uberon def: "A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]." [ISBN:0815318960, OMD:neural+plate, Wikipedia:Neural_plate, ZFIN:curator] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "lamina neuralis" RELATED LATIN [Wikipedia:Neural_plate] synonym: "presumptive central nervous system" RELATED [] xref: AAO:0011072 xref: BTO:0001765 xref: DHBA:10153 xref: DMBA:15565 xref: EHDAA:346 xref: EHDAA:902 xref: EMAPA:35593 xref: FMA:293879 xref: MESH:D054258 xref: NCIT:C34225 xref: neuronames:1362 xref: RETIRED_EHDAA2:0001252 xref: TAO:0000132 xref: UMLS:C0920623 {source="ncithesaurus:Neural_Plate"} xref: VHOG:0000068 xref: Wikipedia:Neural_plate xref: XAO:0000249 xref: ZFA:0000132 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0016879 ! future central nervous system relationship: developmentally_induced_by UBERON:0002328 {source="Wikipedia"} ! notochord relationship: develops_from UBERON:0007284 ! presumptive neural plate relationship: immediate_transformation_of UBERON:0007284 {source="Bgee:AN"} ! presumptive neural plate relationship: only_in_taxon NCBITaxon:7711 {source="GOTAX:0000352"} ! Chordata property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/8/8f/Neural_Crest.png" xsd:anyURI property_value: UBPROP:0000001 "The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000132", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000068", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003076 name: posterior neural tube namespace: uberon xref: AAO:0011082 xref: TAO:0007037 xref: VHOG:0001383 xref: XAO:0000250 xref: ZFA:0007037 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure disjoint_from: UBERON:0003080 {source="lexical"} ! anterior neural tube relationship: develops_from UBERON:0003057 ! chordal neural plate relationship: part_of UBERON:0001049 ! neural tube property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001383", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003077 name: paraxial mesoderm namespace: uberon def: "The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]." [GO:0048339, https://github.com/obophenotype/uberon/issues/30] subset: efo_slim subset: uberon_slim subset: vertebrate_core synonym: "mesoderma paraxiale" RELATED LATIN [Wikipedia:Paraxial_mesoderm] synonym: "paraxial mesenchyme" EXACT [https://github.com/obophenotype/uberon/issues/30, https://github.com/obophenotype/uberon/wiki/The-neural-crest, ZFA:0000255] synonym: "somitic mesoderm" EXACT [ISBN:9780878932504] xref: AAO:0010568 xref: EFO:0003515 xref: EMAPA:16183 xref: EMAPA:16751 xref: FMA:293145 xref: NCIT:C34244 xref: SCTID:361475002 xref: TAO:0000255 xref: UMLS:C1284009 {source="ncithesaurus:Paraxial_Mesoderm"} xref: VHOG:0000114 xref: Wikipedia:Paraxial_mesoderm xref: XAO:0000259 xref: ZFA:0000255 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0015212 ! lateral structure relationship: develops_from UBERON:0007285 ! presumptive paraxial mesoderm relationship: existence_starts_during UBERON:0000109 ! gastrula stage relationship: immediate_transformation_of UBERON:0007285 {source="Bgee:AN"} ! presumptive paraxial mesoderm relationship: in_lateral_side_of UBERON:0000922 ! embryo property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: UBPROP:0000001 "Mesoderm lateral to the neural tube and notochord that is divided into cranial and post-cranial portions. The trunk portions further segment into somites.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010568", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "Presently, Cephalochordata, Urochordata, and Vertebrata are placed as subphyla of the phylum Chordata, in which the overall organization of embryonic tissues (dorsal hollow nerve cord, ventral digestive tract, axial notochord, and bilateral paraxial mesoderm) is largely conserved. In contrast, the echinoderms and hemichordates are sister groups of the chordates and they lack the notochord and paraxial mesoderm. Thus, the basic mesodermal organization of vertebrates must have appeared first in the common ancestor of the chordates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000114", ontology="VHOG", source="DOI:10.1002/dvdy.21177 Kusakabe R and Kuratani S. Evolutionary perspectives from development of mesodermal components in the lamprey. Developmental dynamics (2007)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "note that all AOs differ in the relationship between this structure and the mesoderm; in ZFA it is a subclass (and this is implied by the GO definition and GO relationships), in AAO it is part of, and in EHDAA2 it develops from the mesoderm (but in EHDAA2 the naming convention is to use 'paraxial mesenchyme', rather than 'paraxial mesoderm'). Also in ZFA it is part of the trunk whereas this conflicts with the division into head and trunk in ehdaa2 (which we follow here)" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0003078 name: epibranchial placode namespace: uberon def: "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia." [VHOG:0000117] subset: efo_slim synonym: "epibranchial placodes" EXACT PLURAL [ZFA:0001294] synonym: "ventrolateral placode" RELATED [ISBN:0471888893] xref: AAO:0011036 xref: EFO:0003455 xref: FMA:293968 xref: TAO:0001294 xref: VHOG:0000117 xref: XAO:0000284 xref: ZFA:0001294 is_a: UBERON:0009955 {source="NCBIBook:NBK53175", source="ZFA"} ! neurogenic placode relationship: develops_from UBERON:0000076 {source="EHDAA2-abduced"} ! external ectoderm relationship: has_potential_to_developmentally_contribute_to UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0000010 {source="ZFA"} ! peripheral nervous system property_value: UBPROP:0000001 "Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. [Graham_A, The_development_and_evolution_of_the_pharyngeal_arches._J_Anat_(2001)_199:_133-141][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000117", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "These (the epibranchial placodes) are focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches in all vertebrates, and they produce the neuroblasts which migrate and condense to form the distal cranial ganglia: the geniculate, petrosal and nodose ganglia. (...) The one substantial difference between the vertebrate pharyngeal arches and those of the protochordates is the presence of the epibranchial placodes but the evolution of these structures was undoubtedly driven by the endoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000117", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A, The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "Epibranchial placodes-derived neurons innervate internal organs to transmit information such as heart rate, blood pressure, and visceral distension from the periphery to the central nervous system (Baker and Bronner-Fraser, 2001). From rostral to caudal the epibranchial placodes comprise the geniculate, petrosal, and nodose placodes, each associated in sequence with the first, second and third branchial clefts. Each placode contributes sensory neurons to cranial nerves VII (facial nerve), IX (glossopharyngeal nerve), and X (vagal nerve), respectively" xsd:string {source="NCBIBook:NBK53175"} property_value: UBPROP:0000012 "in XAO this develops_from dorsolateral placode, but in NBK53175, this is a separate group" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0003080 name: anterior neural tube namespace: uberon xref: AAO:0011012 xref: TAO:0007038 xref: VHOG:0001384 xref: XAO:0000307 xref: ZFA:0007038 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0003056 ! pre-chordal neural plate relationship: part_of UBERON:0001049 ! neural tube property_value: editor_note "TODO - add grouping class for the anterior end of the neural tube at all stages" xsd:string property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001384", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003081 name: lateral plate mesoderm namespace: uberon alt_id: UBERON:0006258 def: "Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]." [MP:0010117, Wikipedia:Lateral_plate_mesoderm] subset: pheno_slim subset: uberon_slim synonym: "lateral mesoderm" EXACT [GO:0048368] synonym: "lateral plate" RELATED [] synonym: "lateral plate mesenchyme" RELATED [EHDAA2:0000919] synonym: "LPM" EXACT ABBREVIATION [ZFA:0000121] synonym: "mesoderma laminae lateralis" RELATED LATIN [Wikipedia:Lateral_plate_mesoderm] xref: AAO:0010574 xref: EHDAA2:0000919 xref: EHDAA:379 xref: EMAPA:16179 xref: FMA:293149 xref: NCIT:C34199 xref: SCTID:361477005 xref: TAO:0000121 xref: UMLS:C1517749 {source="ncithesaurus:Lateral_Mesoderm"} xref: VHOG:0000118 xref: Wikipedia:Lateral_plate_mesoderm xref: XAO:0000311 xref: ZFA:0000121 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0000926 {source="EHDAA2", source="VHOG"} ! mesoderm relationship: surrounds UBERON:0003887 ! intraembryonic coelom property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray19_with_color.png" xsd:anyURI property_value: UBPROP:0000001 "Portion of mesoderm traditionally thought to give rise to limb bones and parts of the girdles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010574", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "The portion of the mesoderm of the trunk of vertebrate embryos lying lateral to the intermediate mesoderm. [...] [It] subdivides into two plates: one dorsal, called the somatopleure, and one ventral, called the splanchnopleure. [Gastrulation:_From_cells_to_embryo_(2004)_Cold_Spring_Harbor, Glossary_XV, New_York:_Cold_Spring_Harbor_Laboratory_Press, Stern_CD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000118", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "A ventrolateral zone of amphioxus mesoderm grows down to surround the gut. Homology of this zone to the lateral plate mesoderm of vertebrates is supported by site of origin and fate.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000118", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "subclass of mesoderm in ZFA." xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0003082 name: myotome namespace: uberon def: "A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells." [AEO:0001018] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "muscle plate" RELATED [] synonym: "myomere" RELATED [] synonym: "myomeres" EXACT PLURAL [TAO:0001056] synonym: "myotome region" RELATED [] synonym: "myotomes" RELATED [] synonym: "myotomus" RELATED LATIN [Wikipedia:Myotome] xref: AAO:0011067 xref: AEO:0001018 xref: BTO:0000742 xref: EHDAA2_RETIRED:0003431 xref: EHDAA:1721 xref: EHDAA:1727 xref: EHDAA:1733 xref: EHDAA:1739 xref: EMAPA:32841 xref: FMA:295658 xref: NCIT:C34214 xref: SCTID:344535001 xref: TAO:0001056 xref: UMLS:C1513802 {source="ncithesaurus:Myotome_Region"} xref: VHOG:0001244 xref: Wikipedia:Myotome xref: XAO:0000315 xref: ZFA:0001056 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0017650 {source="AEO"} ! developing mesenchymal structure relationship: contributes_to_morphology_of UBERON:0001630 ! muscle organ relationship: develops_from UBERON:0004290 {source="EHDAA2-abduced"} ! dermomyotome property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png" xsd:anyURI property_value: editor_note "The term 'myotome' is also used to describe the muscles served by a single nerve root / spinal segment - consider adding new class, myomere." xsd:string property_value: UBPROP:0000001 "Portion of the somites giving rise to body wall muscle masses. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001056", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "In all vertebrates, the skeletal muscle of the body axis is chiefly derived from an early embryonic compartment, known as the myotome.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001244", ontology="VHOG", source="DOI:10.1038/sj.embor.embor920 Hollway GE, Currie PD, Myotome meanderings. Cellular morphogenesis and the making of muscle. EMBO Rep.(2003)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003083 name: trunk neural crest namespace: uberon def: "Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]." [ISBN:0815318960, Wikipedia:Trunk_neural_crest] subset: efo_slim subset: uberon_slim synonym: "TNC" EXACT ABBREVIATION [XAO:0000319] synonym: "trunk crest" RELATED [] xref: AAO:0010582 xref: EFO:0003605 xref: EHDAA2:0001901 xref: TAO:0001024 xref: VHOG:0000062 xref: Wikipedia:Trunk_neural_crest xref: XAO:0000319 xref: ZFA:0001024 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: has_part CL:0000011 {source="ZFA"} ! migratory trunk neural crest cell relationship: part_of UBERON:0002342 ! neural crest property_value: UBPROP:0000001 "Post-cranial portion of the neural crest. Exact anatomical derivations not experimentally resolved in amphibians.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010582", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000062", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003084 name: heart primordium namespace: uberon def: "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone." [ZFIN:curator] subset: uberon_slim synonym: "cardiac field" RELATED [ZFA:0000028] synonym: "fused heart primordium" RELATED [] xref: AAO:0011044 xref: BTO:0001887 xref: NCIT:C34276 xref: TAO:0000028 xref: UMLS:C1514450 {source="ncithesaurus:Primordium_of_the_Heart"} xref: XAO:0000336 xref: ZFA:0000028 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: develops_from UBERON:0003081 {source="ZFA"} ! lateral plate mesoderm relationship: develops_from UBERON:0004140 ! primary heart field relationship: develops_from UBERON:0007005 {source="XAO"} ! cardiogenic splanchnic mesoderm relationship: part_of UBERON:0004535 {source="ZFA"} ! cardiovascular system property_value: editor_note "should probably be merged with heart rudiment." xsd:string property_value: UBPROP:0000001 "Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline between 21 and 26 somites to form the heart rudiment or cone. Stainier 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000028", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The fused aspects of ventral mesoderm, which have migrated from either side of the prechordal plate, and fused ventrally, just behind the cement gland. They will give rise to the endocardium at NF stage 27&28.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011044", ontology="AAO", source="XAO:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from lateral mesoderm (TAO:0001065)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000028", ontology="TAO"} [Term] id: UBERON:0003086 name: caudal artery namespace: uberon def: "Extension of the dorsal aorta in the tail." [Wikipedia:Caudal_artery, ZFIN:curator] subset: efo_slim subset: uberon_slim synonym: "CA" RELATED [] xref: AAO:0011023 xref: EFO:0003472 xref: TAO:0000011 xref: VHOG:0000123 xref: Wikipedia:Caudal_artery xref: XAO:0000364 xref: ZFA:0000011 is_a: UBERON:0003513 ! trunk blood vessel is_a: UBERON:0003524 ! tail blood vessel is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: branching_part_of UBERON:0005805 ! dorsal aorta intersection_of: part_of UBERON:0007812 ! post-anal tail relationship: branching_part_of UBERON:0005805 ! dorsal aorta relationship: part_of UBERON:0005805 ! dorsal aorta relationship: part_of UBERON:2001073 ! axial vasculature property_value: UBPROP:0000001 "Extension of the dorsal aorta in the tail. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000011", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The posterior extension of the dorsal aorta to the tail region, which degenerates at metamorphosis.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011023", ontology="AAO", source="ISBN:0-226-55763-4"} [Term] id: UBERON:0003089 name: sclerotome namespace: uberon def: "Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]." [https://github.com/obophenotype/uberon/issues/316, Wikipedia:Sclerotome, XB:curator] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "sclerotomes" EXACT PLURAL [TAO:0001080] synonym: "sclerotomus" RELATED LATIN [Wikipedia:Sclerotome] xref: AAO:0010571 xref: AEO:0000212 xref: EHDAA2:0003439 xref: EMAPA:31159 xref: FMA:295652 xref: NCIT:C34287 xref: TAO:0001080 xref: UMLS:C0183176 {source="ncithesaurus:Sclerotome"} xref: VHOG:0000680 xref: Wikipedia:Sclerotome xref: XAO:0000397 xref: ZFA:0001080 is_a: UBERON:0005856 {source="EHDAA2"} ! developing mesenchymal condensation is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: develops_from UBERON:0002329 {source="ZFA"} ! somite relationship: only_in_taxon NCBITaxon:7742 {source="VHOG:0000680"} ! Vertebrata property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/96/Gray65.png" xsd:anyURI property_value: UBPROP:0000001 "Skeletogenic portion of somites.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010571", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "The vertebrate sclerotome has no equivalent in amphioxus and is a novelty linked with the evolution of the axial skeleton.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000680", ontology="VHOG", source="DOI:10.1073/pnas.97.9.4449 Shimeld SM and Holland PW. Vertebrate innovations. PNAS (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "part_of somite in XAO" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0003099 name: cranial neural crest namespace: uberon def: "Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage." [MGI:anna] subset: efo_slim subset: uberon_slim subset: vertebrate_core synonym: "cephalic neural crest" EXACT [EMAPA:16091] synonym: "CNC" EXACT ABBREVIATION [XAO:0001001] synonym: "cranial NCC population" EXACT [] synonym: "crista neuralis cranialis" RELATED LATIN [Wikipedia:Cranial_neural_crest] synonym: "head crest" RELATED [] synonym: "head NCC population" EXACT [] synonym: "head neural crest" RELATED [] xref: AAO:0010580 xref: EFO:0003645 xref: EHDAA2:0004420 xref: EMAPA:16091 xref: TAO:0001194 xref: VHOG:0000063 xref: Wikipedia:Cranial_neural_crest xref: XAO:0001001 xref: ZFA:0001194 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: has_part CL:0000008 ! migratory cranial neural crest cell relationship: part_of UBERON:0002342 ! neural crest property_value: UBPROP:0000001 "Anterior most portion of the neural crest. Migrates in three highly conserved streams: mandibular, hyoid and branchial.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010580", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Neural crest that is part of the head.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001194", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000063", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003100 name: female organism namespace: uberon def: "Gonochoristic organism that can produce female gametes." [CARO:0000028] subset: pheno_slim subset: vertebrate_core synonym: "female" RELATED [TAO:0000303] synonym: "female human body" NARROW SENSU [FMA:67812] xref: AAO:0010030 xref: BILA:0000028 xref: CARO:0000028 xref: FBbt:00007011 xref: FMA:67812 xref: HAO:0000028 xref: SCTID:362608006 xref: TAO:0000303 xref: TGMA:0001839 xref: XAO:0003005 xref: ZFA:0000303 is_a: UBERON:0000468 ! multicellular organism disjoint_from: UBERON:0003101 ! male organism property_value: RO:0002171 UBERON:0003101 [Term] id: UBERON:0003101 name: male organism namespace: uberon def: "Gonochoristic organism that can produce male gametes." [CARO:0000027] subset: pheno_slim subset: vertebrate_core synonym: "male" RELATED [TAO:0000242] synonym: "male human body" NARROW SENSU [FMA:67811] xref: AAO:0010033 xref: BILA:0000027 xref: CARO:0000027 xref: FBbt:00007004 xref: FMA:67811 xref: HAO:0000027 xref: SCTID:362609003 xref: TAO:0000242 xref: TGMA:0001838 xref: WBbt:0007850 xref: XAO:0003006 xref: ZFA:0000242 is_a: UBERON:0000468 ! multicellular organism [Term] id: UBERON:0003102 name: surface structure namespace: uberon def: "Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/24] subset: upper_level synonym: "anatomical surface feature" EXACT [EHDAA2:0003010] synonym: "surface feature" RELATED [] synonym: "surface region" RELATED [] synonym: "surface structures" RELATED PLURAL [ZFA:0000292] xref: AAO:0010337 xref: AEO_RETIRED:0000010 xref: EHDAA2_RETIRED:0003010 xref: galen:SurfaceRegion xref: TAO:0000292 xref: VSAO:0000001 xref: Wikipedia:Surface_structure xref: XAO:0003028 xref: ZFA:0000292 is_a: UBERON:0000061 ! anatomical structure relationship: adjacent_to UBERON:0013514 ! space surrounding organism relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul property_value: editor_note "consider obsoleting. See issue/1305" xsd:string property_value: UBPROP:0000001 "Organism subdivision which is the collection of anatomical structures on the body surface.[ZFA]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000292", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0003103 name: compound organ namespace: uberon def: "Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types." [CARO:0000024] subset: organ_slim subset: upper_level synonym: "organ" RELATED [] xref: AAO:0010015 xref: AEO:0000024 xref: BILA:0000024 xref: CARO:0000024 xref: EHDAA2:0003024 xref: HAO:0000024 xref: TADS:0000598 xref: TAO:0000496 xref: TGMA:0001837 xref: VHOG:0001723 xref: XAO:0003041 xref: ZFA:0000496 is_a: UBERON:0000062 ! organ property_value: IAO:0000232 "this class was introduced for consistency with CARO. However, in this ontology we typically classify organs directly under 'organ' rather than subdividing into compound and simple organs" xsd:string [Term] id: UBERON:0003104 name: mesenchyme namespace: uberon def: "Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme." [https://archive.org/details/invertebratesnde00brus/page/n240/mode/2up, https://en.wikipedia.org/wiki/Mesenchyme, https://github.com/obophenotype/uberon/issues/1641] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "mesenchyma" RELATED LATIN [Wikipedia:Mesenchyme] synonym: "mesenchymal tissue" EXACT [] synonym: "mesenchyme tissue" EXACT [] synonym: "portion of mesenchymal tissue" EXACT [] synonym: "portion of mesenchyme tissue" EXACT [] xref: AAO:0010427 xref: AEO:0000145 xref: BTO:0001393 xref: CALOHA:TS-0620 xref: EHDAA2:0003145 xref: EV:0100007 xref: NCIT:C13301 xref: TAO:0000393 xref: UMLS:C0162415 {source="ncithesaurus:Mesenchyme"} xref: VHOG:0000170 xref: Wikipedia:Mesenchyme xref: XAO:0003046 xref: ZFA:0000393 is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: composed_primarily_of CL:0008019 ! mesenchymal cell relationship: composed_primarily_of CL:0008019 ! mesenchymal cell relationship: functionally_related_to GO:0032502 ! developmental process relationship: has_developmental_contribution_from UBERON:0000926 {gci_relation="part_of", gci_filler="NCBITaxon:7711"} ! mesoderm relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f4/Mesenchymal_Stem_Cell.jpg" xsd:anyURI property_value: editor_note "the relationship to mesoderm is weaker than develops_from in order to have classes such as 'head mesenchyme from mesoderm' make sense" xsd:string property_value: UBPROP:0000001 "A mesh-like cell arrangement, less compact than an epithelium. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000393", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010427", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000007 "mesenchymal" xsd:string [Term] id: UBERON:0003110 name: otic region namespace: uberon synonym: "cranial vault" RELATED [ZFA:0000189] xref: AAO:0010208 xref: TAO:0000189 xref: XAO:0003175 xref: ZFA:0000189 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium property_value: UBPROP:0000001 "Anatomical cluster that is a posterolateral part of the cranium and structurally supports the vestibuloauditory system.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000189", ontology="TAO", source="TAO:MAH"} property_value: UBPROP:0000001 "Anatomical cluster that is a posterolateral part of the neurocranium and structurally supports the vestibuloauditory system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010208", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000002 "relationship loss: overlaps hyomandibular-otic region joint (TAO:0001947)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000189", ontology="TAO"} property_value: UBPROP:0000012 "UBERONREF:0000007 has this as a syn for otic capsule" xsd:string [Term] id: UBERON:0003111 name: sphenoid region namespace: uberon def: "Anatomical cluster that forms the floor and sidewalls of the middle part of the cranium." [TAO:0000290, UBERONREF:0000007] xref: AAO:0010207 xref: TAO:0000290 xref: XAO:0003174 xref: ZFA:0000290 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium property_value: UBPROP:0000001 "Anatomical cluster that forms the floor and sidewalls of the middle part of the neurocranium.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010207", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0003112 name: olfactory region namespace: uberon def: "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ." [TAO:0000351] subset: efo_slim synonym: "ethmoid region" RELATED [ZFA:0000351] xref: AAO:0010206 xref: EFO:0003525 xref: NCIT:C98765 xref: TAO:0000351 xref: XAO:0003172 xref: ZFA:0000351 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium property_value: UBPROP:0000001 "Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the peripheral olfactory organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000351", ontology="TAO", source="TAO:MAH"} property_value: UBPROP:0000001 "Anatomical cluster that is located in the anterior region of the neurocranium and provides structural support for the olfactory organs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010206", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0003113 name: dermatocranium namespace: uberon def: "Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]." [Wikipedia:Skull_roof, ZFA:0000863] synonym: "dendrocranium" EXACT [TAO:0000863] synonym: "dermal bone cranium" RELATED [ZFA:0000863] synonym: "dermal part of skull" RELATED [] synonym: "dermal skull bones" RELATED [] synonym: "dermal skull roof" NARROW [PMID:11523816, Wikipedia:Skull_roof] synonym: "dermatocranial cover" NARROW [] synonym: "exocranium" EXACT [UBERONREF:0000007] synonym: "roof of skull" NARROW [Wikipedia:Skull_roof] synonym: "roofing bones of the skull" RELATED [Wikipedia:Skull_roof] synonym: "skull exoskeleton" RELATED [] synonym: "skull roof" NARROW [PMID:11523816, Wikipedia:Skull_roof] xref: AAO:0010154 xref: TAO:0000863 xref: VHOG:0001665 xref: Wikipedia:Skull_roof xref: XAO:0003169 xref: ZFA:0000863 is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of UBERON:0010364 ! dermal skeleton property_value: editor_note "wikipedia treats skull roof and dermatocranium as synonymous, but some sources treat the roof as being part of the dermatocranium - see UBERONREF:0000007" xsd:string property_value: RO:0002161 NCBITaxon:7777 {source="ISBN:0073040584"} property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and composed of dermally derived bones.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000863", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium which consists of dermally derived bones.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010154", ontology="AAO", source="AAO:BJB"} [Term] id: UBERON:0003114 name: pharyngeal arch 3 namespace: uberon def: "The third branchial arch contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus." [MP:0006339] subset: pheno_slim subset: vertebrate_core synonym: "3rd arch" RELATED [EHDAA2:0000069] synonym: "3rd pharyngeal arch" EXACT [] synonym: "3rd visceral arch" RELATED [VHOG:0000298] synonym: "branchial arch 1" RELATED SENSU [AAO:0010365, ZFA:0001606] synonym: "first branchial arch" RELATED SENSU [ZFA:0001606] synonym: "first gill arch" EXACT SENSU [ZFA:0001606] synonym: "gill arch 1" EXACT SENSU [ZFA:0001606] synonym: "third pharyngeal arch" EXACT [] synonym: "third visceral arch" EXACT [] synonym: "visceral arch 3" EXACT [] xref: AAO:0010365 xref: EHDAA2:0000069 xref: EHDAA:1080 xref: EMAPA:16399 xref: FMA:293029 xref: SCTID:308769006 xref: TAO:0001598 xref: VHOG:0000298 xref: XAO:0000447 xref: ZFA:0001606 is_a: UBERON:0002539 ! pharyngeal arch property_value: UBPROP:0000001 "The most anterior, or first, pharygeal/branchial arch, composed of the mandibular process, forming the posterior border of the stomodeum, and the maxillary process anterior to the stomodeum, contains the first aortic arch.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010365", ontology="AAO", source="ISBN:0-02-377110-0"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000298", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in XAO, called branchial arch 1 and df VP3" xsd:string {external_ontology="XAO"} property_value: UBPROP:0000103 "3" xsd:nonNegativeInteger [Term] id: UBERON:0003115 name: pharyngeal arch 4 namespace: uberon def: "Contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus." [MP:0006340] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "4th arch" RELATED [EHDAA2:0000086] synonym: "4th branchial arch" EXACT SENSU [] synonym: "4th pharyngeal arch" EXACT [] synonym: "4th visceral arch" EXACT [] synonym: "branchial arch 2" RELATED SENSU [AAO:0010366, ZFA:0001607] synonym: "fourth pharyngeal arch" EXACT [] synonym: "fourth visceral arch" RELATED [VHOG:0000299] synonym: "gill arch 2" EXACT SENSU [ZFA:0001607] synonym: "second branchial arch" RELATED SENSU [ZFA:0001607] synonym: "second gill arch" EXACT SENSU [ZFA:0001607] synonym: "visceral arch 4" EXACT [] xref: AAO:0010366 xref: EHDAA2:0000086 xref: EHDAA:1663 xref: EMAPA:16760 xref: FMA:293035 xref: SCTID:308770007 xref: TAO:0001599 xref: VHOG:0000299 xref: XAO:0000449 xref: ZFA:0001607 is_a: UBERON:0002539 ! pharyngeal arch property_value: UBPROP:0000001 "The second pharyngeal/branchial arch; arises as a thickening of the pharygeal wall between the first and second branchial clefts; contains the second aortic arch; forms part of the hyoid bone, tongue and facial musculature.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010366", ontology="AAO", source="ISBN:0-02-377110-0"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000299", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in XAO, called branchial arch 2 and df VP4" xsd:string {external_ontology="XAO"} property_value: UBPROP:0000103 "4" xsd:nonNegativeInteger [Term] id: UBERON:0003117 name: pharyngeal arch 6 namespace: uberon alt_id: UBERON:0004349 def: "The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles." [MP:0006347] subset: pheno_slim synonym: "6th arch" EXACT [EHDAA2:0004075] synonym: "6th pharyngeal arch" RELATED [VHOG:0001205] synonym: "6th visceral arch" RELATED [VHOG:0001205] synonym: "branchial arch 4" RELATED SENSU [AAO:0010368, ZFA:0001609] synonym: "fourth branchial arch" RELATED SENSU [] synonym: "gill arch 4" EXACT [ZFA:0001609] synonym: "sixth branchial arch" EXACT [] synonym: "sixth pharyngeal arch" RELATED [VHOG:0001205] synonym: "sixth visceral arch" RELATED [XAO:0000453] synonym: "visceral arch 6" EXACT [ZFA:0001609] xref: AAO:0010368 xref: EHDAA2:0004075 xref: EMAPA:32766 xref: FMA:293047 xref: SCTID:308772004 xref: TAO:0001601 xref: VHOG:0001205 xref: XAO:0000453 xref: ZFA:0001609 is_a: UBERON:0002539 ! pharyngeal arch property_value: UBPROP:0000001 "The forth in a series of paired bars in the wall of the pharynx, within which are formed the forth aortic arch and the cartilage bar of the visceral skeleton, forms and supports the gills.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010368", ontology="AAO", source="ISBN:0-02-377110-0"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001205", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M, Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000103 "6" xsd:nonNegativeInteger [Term] id: UBERON:0003118 name: pharyngeal arch artery 1 namespace: uberon alt_id: UBERON:0004371 def: "The vessels formed within the first pair of branchial arches in embryogenesis." [MP:0010355] subset: pheno_slim subset: vertebrate_core synonym: "1st aortic arch artery" RELATED [EMAPA:16685] synonym: "1st arch artery" EXACT [EMAPA:16685] synonym: "1st branchial arch artery" RELATED [EMAPA:16685] synonym: "1st pharyngeal arch artery" RELATED [EMAPA:16685] synonym: "AA1" EXACT [ZFA:0005005] synonym: "aortic arch 1" EXACT [ZFA:0005005] synonym: "first aortic arch" EXACT [XAO:0000342] synonym: "first arch artery" RELATED [EMAPA:16685] synonym: "first branchial arch artery" EXACT [] synonym: "mandibular aortic arch" EXACT [ZFA:0005005] xref: AAO:0010415 xref: EHDAA2:0000007 xref: EMAPA:16202 xref: EMAPA:16685 xref: SCTID:308774003 xref: TAO:0005005 xref: VHOG:0000149 xref: XAO:0000342 xref: ZFA:0005005 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: part_of UBERON:0004362 ! pharyngeal arch 1 relationship: contributes_to_morphology_of UBERON:0004362 ! pharyngeal arch 1 relationship: part_of UBERON:0004362 ! pharyngeal arch 1 property_value: UBPROP:0000008 "Disappears early in development in tetrapods" xsd:string property_value: UBPROP:0000012 "ZFA states that The paired aortic arch 1 arteries branch off of the ventral aorta, and empty into the right and left lateral dorsal aortas" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0003119 name: pharyngeal arch artery 2 namespace: uberon alt_id: UBERON:0004372 def: "The vessels formed within the second pair of branchial arches in embryogenesis." [MP:0010356] subset: pheno_slim subset: vertebrate_core synonym: "2nd aortic arch artery" RELATED [EMAPA:16686] synonym: "2nd arch artery" EXACT [EHDAA2:0000051] synonym: "2nd branchial arch artery" RELATED [EMAPA:16686] synonym: "2nd pharyngeal arch artery" RELATED [EMAPA:16686] synonym: "AA2" EXACT [ZFA:0005006] synonym: "aortic arch 2" EXACT [ZFA:0005006] synonym: "hyoid aortic arch" EXACT [ZFA:0005006] synonym: "second aortic arch" EXACT [XAO:0000343] synonym: "second branchial arch artery" EXACT [] xref: AAO:0010418 xref: EHDAA2:0000051 xref: EMAPA:16203 xref: EMAPA:16686 xref: SCTID:308775002 xref: TAO:0005006 xref: VHOG:0000148 xref: Wikipedia:Aortic_arches#Arches_1_and_2 xref: XAO:0000343 xref: ZFA:0005006 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 relationship: contributes_to_morphology_of UBERON:0003066 ! pharyngeal arch 2 relationship: part_of UBERON:0003066 ! pharyngeal arch 2 property_value: UBPROP:0000001 "The first and second arches disappear early, but the dorsal end of the second gives origin to the stapedial artery, a vessel which atrophies in humans but persists in some mammals. It passes through the ring of the stapes and divides into supraorbital, infraorbital, and mandibular branches which follow the three divisions of the trigeminal nerve. The infraorbital and mandibular arise from a common stem, the terminal part of which anastomoses with the external carotid. On the obliteration of the stapedial artery this anastomosis enlarges and forms the internal maxillary artery, and the branches of the stapedial artery are now branches of this vessel. The common stem of the infraorbital and mandibular branches passes between the two roots of the auriculotemporal nerve and becomes the middle meningeal artery; the original supraorbital branch of the stapedial is represented by the orbital twigs of the middle meningeal[WP][Wikipedia:Aortic_arches#Arches_1_and_2]." xsd:string {source="Wikipedia:Aortic_arches#Arches_1_and_2"} property_value: UBPROP:0000001 "The second in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 2 that is part of hyoid arch.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010418", ontology="AAO", source="ISBN:0-02-377110-0"} [Term] id: UBERON:0003120 name: pharyngeal arch artery 3 namespace: uberon alt_id: UBERON:0004352 def: "The vessels formed within the third pair of branchial arches in embryogenesis." [MP:0006356] subset: pheno_slim subset: vertebrate_core synonym: "3rd aortic arch artery" RELATED [EMAPA:16687] synonym: "3rd arch artery" EXACT [EHDAA2:0000070] synonym: "3rd branchial arch artery" RELATED [EMAPA:16687] synonym: "3rd pharyngeal arch artery" RELATED [EMAPA:16687] synonym: "AA3" EXACT [ZFA:0005007] synonym: "aortic arch 3" EXACT [ZFA:0005007] synonym: "carotid arch" EXACT [Wikipedia:Aortic_arches#Arch_3] synonym: "third aortic arch" EXACT [XAO:0000344] synonym: "third branchial arch artery" EXACT [] xref: AAO:0010419 xref: EHDAA2:0000070 xref: EMAPA:16687 xref: SCTID:308776001 xref: TAO:0005007 xref: VHOG:0000147 xref: Wikipedia:Aortic_arches#Arch_3 xref: XAO:0000344 xref: ZFA:0005007 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 relationship: contributes_to_morphology_of UBERON:0003114 ! pharyngeal arch 3 relationship: part_of UBERON:0003114 ! pharyngeal arch 3 property_value: UBPROP:0000001 "Aortic arches 3 and 4 are not remodeled but are retained largely intact as the branchial arteries providing circulation through the gills. These areches are direct branches from the ventral aorta to the lateral dorsal aorta. Isogai et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005007", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The third aortic arch constitutes the commencement of the internal carotid artery, and is therefore named the carotid arch[WP][Wikipedia:Aortic_arches#Arch_3]." xsd:string {source="Wikipedia:Aortic_arches#Arch_3"} property_value: UBPROP:0000001 "The third in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 3 lies within the 3rd branchial arch and branches directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010419", ontology="AAO", source="ISBN:0-02-377110-0"} [Term] id: UBERON:0003121 name: pharyngeal arch artery 4 namespace: uberon alt_id: UBERON:0004350 def: "The vessels formed within the fourth pair of branchial arches in embryogenesis." [MP:0006354] comment: proximal right subclavian subset: pheno_slim subset: vertebrate_core synonym: "4th aortic arch artery" RELATED [EMAPA:17004] synonym: "4th arch artery" EXACT [EHDAA2:0000087] synonym: "4th branchial arch artery" RELATED [EMAPA:17004] synonym: "4th pharyngeal arch artery" RELATED [EMAPA:17004] synonym: "AA4" EXACT [ZFA:0005008] synonym: "aortic arch 4" EXACT [ZFA:0005008] synonym: "fourth aortic arch" EXACT [XAO:0000355] synonym: "fourth branchial arch artery" EXACT [] synonym: "systemic arch" RELATED [ISBN:0073040584, XAO:0000355] xref: AAO:0010420 xref: EHDAA2:0000087 xref: EMAPA:17004 xref: SCTID:308777005 xref: TAO:0005008 xref: Wikipedia:Aortic_arches#Arch_4 xref: XAO:0000355 xref: ZFA:0005008 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 relationship: part_of UBERON:0003115 ! pharyngeal arch 4 property_value: UBPROP:0000001 "Aortic arches 3 and 4 are not remodeled but are retained largely intact as the branchial arteries providing circulation through the gills. These areches are direct branches from the ventral aorta to the lateral dorsal aorta. Isogai et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005008", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The forth in a series paired arterial connections between the dorsal and ventral aortae, lies within the 4th branchial arch. The paired aortic arch 4 arteries branch directly from the ventral aorta to the lateral dorsal aorta, and are retained as the branchial arteries providing circulation through the gills in the adult.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010420", ontology="AAO", source="ISBN:0-02-377110-0"} property_value: UBPROP:0000001 "The fourth right arch forms the right subclavian as far as the origin of its internal mammary branch; while the fourth left arch constitutes the arch of the aorta between the origin of the left carotid artery and the termination of the ductus arteriosus[WP][Wikipedia:Aortic_arches#Arch_4]." xsd:string {source="Wikipedia:Aortic_arches#Arch_4"} property_value: UBPROP:0000011 "Normally, the left fourth arch becomes the aortic arch, the right fourth arch contributes to the innominate artery[http://emedicine.medscape.com/article/899609-overview] in birds it is the right fourth arch which forms the permanent aorta" xsd:string [Term] id: UBERON:0003123 name: pharyngeal arch artery 6 namespace: uberon alt_id: UBERON:0004351 def: "The vessels formed within the sixth pair of branchial arches in embryogenesis." [MP:0006355] subset: pheno_slim subset: vertebrate_core synonym: "6th aortic arch artery" RELATED [EMAPA:17005] synonym: "6th arch artery" EXACT [EMAPA:17005] synonym: "6th branchial arch artery" RELATED [EMAPA:17005] synonym: "6th pharyngeal arch artery" RELATED [EMAPA:17005] synonym: "AA6" EXACT [ZFA:0005016] synonym: "aortic arch 6" EXACT [ZFA:0005016] synonym: "pulmonary arch" RELATED [ISBN:0073040584] synonym: "sixth aortic arch" EXACT [XAO:0000353] synonym: "sixth branchial arch artery" EXACT [] xref: AAO:0010422 xref: EHDAA2:0000102 xref: EMAPA:17005 xref: SCTID:308779008 xref: TAO:0005016 xref: VHOG:0000144 xref: Wikipedia:Aortic_arches#Arch_6 xref: XAO:0000353 xref: ZFA:0005016 is_a: UBERON:0004363 ! pharyngeal arch artery intersection_of: UBERON:0004363 ! pharyngeal arch artery intersection_of: part_of UBERON:0003117 ! pharyngeal arch 6 relationship: part_of UBERON:0003117 ! pharyngeal arch 6 property_value: UBPROP:0000001 "The fifth and sixth arches, which come on-line at approximately 2.5 dpf, have a common trunk from the ventral aorta and drain to the midline dorsal aorta via an independent route. The fifth and sixth aortic arches supply the trunk and tail with oxigenated blood. Isogai et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005016", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The sixth in a series paired arterial connections between the dorsal and ventral aortae. Aortic arch 6 artery is paired and has a common trunk with aortic arch 5 from the ventral aorta, and drains via a separate branch of the lateral dorsal aorta. It forms part of the pulmonary arteries, and in the later embryo, the ductus arteriosis. Aortic arches 5 and 6 together supply the trunk and tail with oxygenated blood.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010422", ontology="AAO", source="ISBN:0-02-377110-0"} property_value: UBPROP:0000001 "The sixth right arch disappears; the sixth left arch gives off the pulmonary arteries and forms the ductus arteriosus; this duct remains pervious during the whole of fetal life, but then closes within the first few days after birth due to increased O2 concentration. Oxygen concentration causes the production of bradykinin which causes the ductus to constrict occluding all flow. Within 1-3 months, the ductus is obliterated and becomes the ligamentum arteriosus. His showed that in the early embryo the right and left arches each gives a branch to the lungs, but that later both pulmonary arteries take origin from the left arch[WP][Wikipedia:Aortic_arches#Arch_6]." xsd:string {source="Wikipedia:Aortic_arches#Arch_6"} property_value: UBPROP:0000011 "the distal left sixth arch becomes the ductus arteriosus, the proximal sixth arches bilaterally contribute to the proximal branch pulmonary arteries" xsd:string {source="http://emedicine.medscape.com/article/899609-overview"} [Term] id: UBERON:0003124 name: chorion membrane namespace: uberon def: "The outermost extraembryonic membrane of amniotes." [http://orcid.org/0000-0002-6601-2165, https://github.com/geneontology/go-ontology/issues/22603, MESH:A10.615.284.473, MP:0002836] comment: This term refers to the amniote structure. It is distinct from the concept of chorion in insects subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "chorion" EXACT [] synonym: "chorion (vertebrates)" EXACT [] synonym: "chorion frondosum" RELATED [Wikipedia:Chorion] synonym: "chorionic sac" RELATED [Wikipedia:Chorion] synonym: "embryonic chorion" EXACT [] synonym: "fetal chorion" EXACT [] synonym: "uterine chorion" EXACT [http://orcid.org/0000-0002-6601-2165, ZFIN:curator] xref: BTO:0000252 xref: CALOHA:TS-0144 xref: EFO:0002780 xref: EHDAA2:0000245 xref: EHDAA:150 xref: EMAPA:16112 xref: EV:0100121 xref: FMA:80224 xref: GAID:1299 xref: MESH:D002823 xref: NCIT:C34122 xref: NCIT:C34124 xref: UMLS:C0008503 {source="ncithesaurus:Chorion"} xref: UMLS:C1516505 {source="ncithesaurus:Chorionic_Sac"} xref: VHOG:0000200 xref: Wikipedia:Chorion is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005631 ! extraembryonic membrane relationship: adjacent_to UBERON:0000922 ! embryo relationship: develops_from UBERON:0005971 {source="ISBN:0073040584"} ! amniotic fold relationship: has_part UBERON:0003265 ! chorionic mesenchyme relationship: has_part UBERON:0003374 ! chorionic ectoderm relationship: only_in_taxon NCBITaxon:32524 {source="Hymans"} ! Amniota property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/51/Gray24.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The outer membrane enclosing the embryo in reptiles, birds, and mammals. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000200", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/chorion"} property_value: UBPROP:0000001 "The outer membrane of the two membranes enclosing the embryo in reptiles, birds, and mammals. In placental mammals it contributes to the development of the placenta[BTO:0000252]." xsd:string {source="BTO:0000252"} property_value: UBPROP:0000003 "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000200", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.187", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "chorionic" xsd:string property_value: UBPROP:0000008 "The chorion of placentals is bilaminar as in reptiles and birds, but forms from the trophoblast and includes the ajdacent mesodermal layer [ISBN:0073040584]" xsd:string property_value: UBPROP:0000011 "Extra-embryonic ectoderm" xsd:string {source="PMID:19829370"} [Term] id: UBERON:0003126 name: trachea namespace: uberon def: "The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]." [GO:0060438, Wikipedia:Vertebrate_trachea] subset: efo_slim subset: human_reference_atlas subset: major_organ subset: pheno_slim subset: uberon_slim synonym: "cartilaginous trachea" EXACT [] synonym: "tracheal tubule" RELATED [BTO:0001388] synonym: "vertebrate trachea" EXACT SENSU [] synonym: "windpipe" EXACT [] xref: AAO:0010140 xref: BTO:0001388 xref: CALOHA:TS-1060 xref: EFO:0000935 xref: EHDAA2:0002066 xref: EHDAA:3078 xref: EMAPA:16853 xref: EV:0100040 xref: FMA:7394 xref: GAID:361 xref: MA:0000441 xref: MAT:0000137 xref: MESH:D014132 xref: MIAA:0000137 xref: NCIT:C12428 xref: SCTID:181213009 xref: UMLS:C0040578 {source="ncithesaurus:Trachea"} xref: VHOG:0000371 xref: Wikipedia:Vertebrate_trachea xref: XAO:0000118 is_a: UBERON:0000117 ! respiratory tube relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system relationship: develops_from UBERON:0008947 {source="EHDAA2"} ! respiratory primordium relationship: located_in UBERON:0002224 ! thoracic cavity relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0007196 ! tracheobronchial tree property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9f/Illu_conducting_passages.svg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c3/Illu_conducting_passages.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "An elongated tube which carries air to and from the lungs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010140", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "The respiratory tube between the larynx and the bronchi. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-29, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000371", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In primitive fishes and most tetrapods, the lungs of adults are usually paired. They lie ventral to the digestive tract and are connected to the outside environment through the trachea.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000371", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.409", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "tracheal" xsd:string property_value: UBPROP:0000008 "In birds, the trachea runs from the pharynx to the syrinx, from which the primary bronchi diverge. Swans have an unusually elongated trachea, part of which is coiled beneath the sternum; this may act as a resonator to amplify sound. In some birds, the cartilagenous rings are complete, and may even be ossified. In amphibians, the trachea is normally extremely short, and leads directly into the lungs, without clear primary bronchi. A longer trachea is, however found in some long-necked salamanders, and in caecilians. While there are irregular cartilagenous nodules on the amphibian trachea, these do not form the rings found in amniotes. The only vertebrate to have lungs, but no trachea, is Polypterus, in which the lungs arise directly from the pharynx." xsd:string property_value: UBPROP:0000008 "in mouse 15-18 C-rings, 15-20 in human." xsd:string {source="ISBN:0123813611"} [Term] id: UBERON:0003128 name: cranium namespace: uberon def: "Upper portion of the skull that excludes the mandible (when present in the organism)." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Cranium_(anatomy)] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "bones of cranium" EXACT [FMA:71325] synonym: "calvarium" RELATED [BTO:0001328] synonym: "epicranial plate" RELATED [] synonym: "ossa cranii" EXACT LATIN [FMA:71325, FMA:TA] synonym: "set of bones of cranium" EXACT [FMA:71325] synonym: "skeletal system of head" RELATED [] synonym: "skull minus mandible" EXACT [] synonym: "upper part of skull" EXACT [] xref: BTO:0001328 xref: EFO:0000831 xref: EHDAA:6029 xref: EMAPA:17680 xref: FMA:71325 xref: MA:0000316 xref: MAT:0000340 xref: MIAA:0000340 xref: SCTID:181889008 xref: VHOG:0000334 xref: Wikipedia:Cranium_(anatomy) is_a: UBERON:0000075 {source="FMA-inferred"} ! subdivision of skeletal system relationship: part_of UBERON:0003129 ! skull property_value: RO:0002171 UBERON:0003278 property_value: UBPROP:0000007 "cranial" xsd:string property_value: UBPROP:0000012 "the inclusion of the FMA class here is probably not quite correct, as this class includes as parts sutures, whereas this is not part of the bones of the cranium" xsd:string {external_ontology="FMA"} property_value: UBPROP:0000013 "The term cranium can be ambiguous, in that it can refer to the neurocranium, or the neurocranium and the Facial skeleton" xsd:string {source="WP"} [Term] id: UBERON:0003129 name: skull namespace: uberon def: "Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]." [http://sourceforge.net/tracker/?func=detail&aid=2962656&group_id=76834&atid=1205376, PMID:11523816, Wikipedia:Skull] subset: pheno_slim subset: uberon_slim synonym: "cranial skeleton" RELATED [] synonym: "skeletal system of head" RELATED [] xref: BTO:0001295 xref: CALOHA:TS-2344 xref: EHDAA2:0000325 xref: EMAPA:17680 xref: FMA:46565 xref: GAID:82 xref: galen:Skull xref: MESH:D012886 xref: NCIT:C12789 xref: SCTID:110530005 xref: UMLS:C0037303 {source="ncithesaurus:Skull"} xref: Wikipedia:Skull xref: WikipediaCategory:Skull is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: has_part UBERON:0003128 ! cranium relationship: has_part UBERON:0003278 ! skeleton of lower jaw relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of UBERON:0000033 ! head relationship: part_of UBERON:0010323 ! cranial skeletal system property_value: RO:0002175 NCBITaxon:7762 property_value: UBPROP:0000012 "in FMA the skull is divided into orbit, neurocranium (8 parts), viscerocranium (26 parts). Here we have a separate overlapping division into cranium and mandible." xsd:string {external_ontology="FMA"} property_value: UBPROP:0000012 "in many ontologies, the structure called the cranium is inclusive of the mandible/lower jaw skeleton" xsd:string property_value: UBPROP:0000013 "A skull that is missing a mandible is only a cranium; this is the source of a very commonly made error in terminology. Those animals having skulls are called craniates" xsd:string {source="WP"} [Term] id: UBERON:0003133 name: reproductive organ namespace: uberon def: "An organ involved in reproduction." [UBERON:xp] subset: functional_classification subset: organ_slim subset: pheno_slim synonym: "genital organ" EXACT [] synonym: "genitalia" RELATED PLURAL [] synonym: "reproductive system organ" EXACT [] synonym: "sex organ" EXACT [] xref: EMAPA:17381 xref: EMAPA:37731 {source="MA:th"} xref: MA:0001752 xref: MESH:D005835 xref: NCIT:C25177 xref: SCTID:128181006 xref: TGMA:0000591 xref: UMLS:C0017420 {source="ncithesaurus:Genitalia"} xref: WBbt:0008422 is_a: UBERON:0000062 ! organ is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000062 ! organ intersection_of: capable_of_part_of GO:0000003 ! reproduction relationship: capable_of_part_of GO:0000003 ! reproduction property_value: UBPROP:0000012 "GO uses genitalia for the singular organ" xsd:string {external_ontology="GO"} [Term] id: UBERON:0003134 name: female reproductive organ namespace: uberon def: "A female organ involved in reproduction." [UBERON:xp] subset: organ_slim subset: pheno_slim synonym: "female organism reproductive organ" EXACT [OBOL:automatic] synonym: "female organism reproductive structure" EXACT [OBOL:automatic] synonym: "female organism reproductive system organ" EXACT [OBOL:automatic] synonym: "female organism sex organ" EXACT [OBOL:automatic] synonym: "female reproductive gland/organ" EXACT [MA:0000544] synonym: "female reproductive system organ" EXACT [] synonym: "female sex organ" EXACT [] synonym: "reproductive organ of female organism" EXACT [OBOL:automatic] synonym: "reproductive structure of female organism" EXACT [OBOL:automatic] synonym: "reproductive system organ of female organism" EXACT [OBOL:automatic] synonym: "sex organ of female organism" EXACT [OBOL:automatic] xref: EMAPA:28540 xref: MA:0000544 is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0000474 ! female reproductive system [Term] id: UBERON:0003135 name: male reproductive organ namespace: uberon def: "A male organ involved in reproduction." [UBERON:xp] subset: organ_slim subset: pheno_slim synonym: "male genital" RELATED [WBbt:0008423] synonym: "male organism reproductive organ" EXACT [OBOL:automatic] synonym: "male organism reproductive structure" EXACT [OBOL:automatic] synonym: "male organism reproductive system organ" EXACT [OBOL:automatic] synonym: "male organism sex organ" EXACT [OBOL:automatic] synonym: "male reproductive gland/organ" EXACT [MA:0000545] synonym: "male reproductive system organ" EXACT [] synonym: "male sex organ" EXACT [] synonym: "reproductive organ of male organism" EXACT [OBOL:automatic] synonym: "reproductive structure of male organism" EXACT [OBOL:automatic] synonym: "reproductive system organ of male organism" EXACT [OBOL:automatic] synonym: "sex organ of male organism" EXACT [OBOL:automatic] xref: MA:0000545 xref: WBbt:0008423 is_a: UBERON:0003133 ! reproductive organ intersection_of: UBERON:0003133 ! reproductive organ intersection_of: part_of UBERON:0003101 ! male organism relationship: part_of UBERON:0000079 ! male reproductive system [Term] id: UBERON:0003212 name: gustatory organ namespace: uberon def: "Any sense organ that functions in (some) detection of chemical stimulus involved in sensory perception of taste (GO:0050912)." [FBC:auto_generated_definition] synonym: "gustatory organ system organ" EXACT [OBOL:automatic] synonym: "gustatory system organ" EXACT [OBOL:automatic] synonym: "organ of gustatory organ system" EXACT [OBOL:automatic] synonym: "organ of gustatory system" EXACT [OBOL:automatic] synonym: "organ of taste system" EXACT [OBOL:automatic] synonym: "taste organ" EXACT [] synonym: "taste system organ" EXACT [OBOL:automatic] xref: FBbt:00005159 xref: FMA:77853 is_a: UBERON:0000005 ! chemosensory organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of_part_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste relationship: capable_of_part_of GO:0050912 ! detection of chemical stimulus involved in sensory perception of taste relationship: part_of UBERON:0001033 ! gustatory system [Term] id: UBERON:0003216 name: hard palate namespace: uberon def: "Anterior portion of the palate consisting of bone and mucous membranes [GO]. The hard palate is formed from bony processes of the maxilla, premaxilla and palatine bone [Kardong]." [GO:0060022, Wikipedia:Hard_palate] subset: pheno_slim subset: uberon_slim synonym: "hard palate" EXACT [] synonym: "palatum durum" EXACT LATIN [Wikipedia:Hard_palate] xref: EMAPA:18952 xref: FMA:55023 xref: GAID:221 xref: MA:0002477 xref: MAT:0000161 xref: MESH:D021362 xref: MIAA:0000161 xref: NCIT:C12230 xref: SCTID:245778002 xref: UMLS:C0226901 {source="ncithesaurus:Hard_Palate"} xref: Wikipedia:Hard_palate is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0034921 {source="FMA"} ! multi organ part structure relationship: part_of UBERON:0001716 {notes="check this", source="EMAPA"} ! secondary palate property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/f/f6/Illu_mouth.jpg" xsd:anyURI property_value: UBPROP:0000012 "in FMA this is divided into bony parts and submucosa" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003218 name: ovary septum namespace: uberon def: "Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]." [GO:0080126] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003037 ! septum intersection_of: UBERON:0003037 ! septum intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0000992 ! ovary [Term] id: UBERON:0003220 name: metanephric mesenchyme namespace: uberon def: "One of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO]." [GO:0072075, Wikipedia:Metanephric_blastema] comment: Genes: The positional specification of the metanephrogenic mesenchyme is negatively regulated by Foxc1 and Foxc2. Next the permanent kidney forming metanephrogenic mesenchyme is specified by Hox11 genes. The competence to respond to ureteric bud inducers is regulated by WT1. GDNF secretion restricted to posterior region by Robo2 and Sprouty1. The receptors for GDNF are synthesized in the nephric ducts and later in ureteric buds [ISBN:9780878932504 "Developmental Biology"] subset: pheno_slim synonym: "metanephric blastema" EXACT [Wikipedia:Metanephric_blastema] synonym: "metanephric mesoderm" EXACT [Wikipedia:Metanephric_blastema] synonym: "metanephrogenic mesenchyme" EXACT [EHDAA:5021] synonym: "metanephros associated mesenchyme" EXACT [RETIRED_EHDAA2:0001139] xref: EHDAA2:0004062 xref: EHDAA:4041 xref: EHDAA:5021 xref: EHDAA:5915 xref: EMAPA:17375 xref: SCTID:361529008 xref: VHOG:0000540 xref: Wikipedia:Metanephric_blastema is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0003918 ! kidney mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: has_potential_to_develop_into UBERON:0000081 ! metanephros relationship: developmentally_induced_by UBERON:0000084 {source="ISBN:9780878932504"} ! ureteric bud relationship: develops_from UBERON:0003074 ! mesonephric duct relationship: has_potential_to_develop_into UBERON:0000081 ! metanephros property_value: UBPROP:0000001 "A mass of intermediate mesodermal cells around the distal end of the ureteric bud that gives rise to nephrons in the metanephric kidney. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000540", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/metanephric+mesenchyme"} property_value: UBPROP:0000003 "When the ureteric buds emerge from the nephric duct, they enter the metanephrogenic mesenchyme. The ureteric buds induce this mesenchymal tissue to condense around them and differentiate into the nephrons of the mammalian kidney. As this mesenchyme differentiates, it tells the ureteric bud to branch and grow.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000540", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.462", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003221 name: phalanx namespace: uberon def: "Endochondral bones that are often elongate and arranged in rows of articulating elements, and form the visible part of the digits." [VSAO:0000199, Wikipedia:Phalanx_bones] subset: pheno_slim synonym: "digit long bone" EXACT [OBOL:automatic] synonym: "long bone of digit" EXACT [OBOL:automatic] synonym: "phalange" EXACT [] synonym: "phalanges" EXACT PLURAL [] synonym: "phalanx bone" EXACT [Wikipedia:Phalanx_bones] xref: CALOHA:TS-2211 xref: EMAPA:32614 xref: FMA:321661 xref: galen:Phalanx xref: MA:0000304 xref: NCIT:C33317 xref: SCTID:290029003 xref: UMLS:C0222682 {source="ncithesaurus:Phalanx"} xref: VSAO:0000199 xref: Wikipedia:Phalanx_bones is_a: UBERON:0003606 ! limb long bone is_a: UBERON:0012357 ! digitopodium bone is_a: UBERON:0015023 ! phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010701 ! phalanx cartilage element relationship: part_of UBERON:5102544 ! individual digit of digitopodial skeleton property_value: UBPROP:0000007 "phalangeal" xsd:string property_value: UBPROP:0000008 "In primates such as humans and monkeys, the thumb and big toe have two phalanges, while the other fingers and toes consist of three" xsd:string {source="WP"} [Term] id: UBERON:0003229 name: epithelium of elbow namespace: uberon def: "An epithelium that is part of a elbow [Automatically generated definition]." [OBOL:automatic] synonym: "cubital region epithelial tissue" EXACT [OBOL:automatic] synonym: "cubital region epithelium" EXACT [OBOL:automatic] synonym: "elbow epithelial tissue" EXACT [OBOL:automatic] synonym: "elbow epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of cubital region" EXACT [OBOL:automatic] synonym: "epithelial tissue of elbow" EXACT [OBOL:automatic] synonym: "epithelium of cubital region" EXACT [OBOL:automatic] xref: EHDAA2:0000430 xref: EHDAA:4168 xref: EHDAA:6214 xref: EMAPA:17415 xref: VHOG:0001044 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001461 ! elbow relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0001461 ! elbow [Term] id: UBERON:0003230 name: epithelium of carpal region namespace: uberon def: "An epithelium that is part of a wrist [Automatically generated definition]." [OBOL:automatic] synonym: "carpal region epithelial tissue" EXACT [OBOL:automatic] synonym: "carpal region epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of carpal region" EXACT [OBOL:automatic] synonym: "epithelial tissue of wrist" EXACT [OBOL:automatic] synonym: "epithelium of wrist" EXACT [OBOL:automatic] synonym: "wrist epithelial tissue" EXACT [OBOL:automatic] synonym: "wrist epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0000219 xref: EHDAA:5198 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004452 ! carpal region relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0003231 name: epithelium of hip namespace: uberon def: "An epithelium that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of hip" EXACT [OBOL:automatic] synonym: "epithelial tissue of hip region" EXACT [OBOL:automatic] synonym: "epithelial tissue of regio coxae" EXACT [OBOL:automatic] synonym: "epithelium of hip region" EXACT [OBOL:automatic] synonym: "epithelium of regio coxae" EXACT [OBOL:automatic] synonym: "hip epithelial tissue" EXACT [OBOL:automatic] synonym: "hip epithelium" EXACT [OBOL:automatic] synonym: "hip region epithelial tissue" EXACT [OBOL:automatic] synonym: "hip region epithelium" EXACT [OBOL:automatic] synonym: "regio coxae epithelial tissue" EXACT [OBOL:automatic] synonym: "regio coxae epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0000784 xref: EHDAA:5155 xref: EHDAA:6180 xref: EMAPA:17491 xref: VHOG:0000779 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001464 ! hip relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm relationship: part_of UBERON:0001464 ! hip [Term] id: UBERON:0003232 name: epithelium of knee namespace: uberon def: "An epithelium that is part of a knee [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of knee" EXACT [OBOL:automatic] synonym: "knee epithelial tissue" EXACT [OBOL:automatic] synonym: "knee epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0000896 xref: EHDAA:5161 xref: EHDAA:6186 xref: EMAPA:17494 xref: VHOG:0000810 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001465 ! knee relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm relationship: part_of UBERON:0001465 ! knee [Term] id: UBERON:0003233 name: epithelium of shoulder namespace: uberon def: "An epithelium that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of shoulder" EXACT [OBOL:automatic] synonym: "shoulder epithelial tissue" EXACT [OBOL:automatic] synonym: "shoulder epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0001835 xref: EHDAA:4182 xref: EHDAA:6230 xref: EMAPA:17422 xref: VHOG:0000761 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001467 ! shoulder relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0001467 ! shoulder [Term] id: UBERON:0003235 name: epithelium of upper jaw namespace: uberon def: "An epithelium that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "epithelial tissue of upper jaw" EXACT [OBOL:automatic] synonym: "epithelium of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "palatoquadrate arch epithelial tissue" EXACT [OBOL:automatic] synonym: "palatoquadrate arch epithelium" EXACT [OBOL:automatic] synonym: "upper jaw epithelial tissue" EXACT [OBOL:automatic] synonym: "upper jaw epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0002119 xref: EHDAA:8027 xref: EMAPA:17943 xref: EMAPA:18971 is_a: UBERON:0035037 ! jaw epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0003236 name: epithelium of lower jaw namespace: uberon def: "An epithelium that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lower jaw" EXACT [OBOL:automatic] synonym: "epithelial tissue of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "epithelium of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "lower jaw epithelial tissue" EXACT [OBOL:automatic] synonym: "lower jaw epithelium" EXACT [OBOL:automatic] synonym: "ventral mandibular arch epithelial tissue" EXACT [OBOL:automatic] synonym: "ventral mandibular arch epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0001019 xref: EHDAA:7999 xref: EMAPA:35516 xref: VHOG:0000802 is_a: UBERON:0035037 ! jaw epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0003247 name: epithelium of forearm namespace: uberon def: "An epithelium that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "forearm epithelium" EXACT [] xref: EHDAA2:0000554 xref: EHDAA:4174 xref: EHDAA:6220 xref: EMAPA:17418 xref: VHOG:0001096 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0002386 ! forelimb zeugopod [Term] id: UBERON:0003248 name: epithelium of footplate namespace: uberon def: "An epithelium that is part of a footplate." [OBOL:automatic] synonym: "foot plate epithelium" EXACT [] synonym: "footplate epithelium" EXACT [EHDAA2:0000548] xref: EHDAA2:0000548 xref: EHDAA:5145 xref: EHDAA:6144 xref: EMAPA:32655 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006871 ! embryonic footplate relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0006871 ! embryonic footplate [Term] id: UBERON:0003249 name: epithelium of otic placode namespace: uberon def: "An epithelium that is part of a otic placode [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of otic placode" EXACT [OBOL:automatic] synonym: "otic epithelium" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "otic placode epithelial tissue" EXACT [OBOL:automatic] synonym: "otic placode epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0001341 xref: EHDAA:510 xref: EMAPA:16197 xref: VHOG:0000636 xref: ZFA:0007068 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0015807 ! ear epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003069 ! otic placode relationship: part_of UBERON:0003069 ! otic placode property_value: editor_note "check ZFA, placemeant, appears to refer to both adult structures and primordium" xsd:string [Term] id: UBERON:0003252 name: thoracic rib cage namespace: uberon def: "Subdivision of skeletal system that consists of all ribs in an organism connected to the sternum and the vertebrae. Some vertebrates have abdominal ribs (gastrialia), not connected to the vertebrate - these are not considered part of the rib case." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "cavea thoracis" EXACT LATIN [FMA:7480, FMA:TA] synonym: "cavea thoracis" RELATED LATIN [Wikipedia:Human_rib_cage] synonym: "rib cage" EXACT [FMA:7480] synonym: "thoracic cage" EXACT [FMA:7480] xref: FMA:7480 xref: galen:RibCage xref: SCTID:361741004 xref: Wikipedia:Human_rib_cage xref: Wikipedia:Rib_cage is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010912 ! subdivision of skeleton relationship: contributes_to_morphology_of UBERON:0005944 ! axial skeleton plus cranial skeleton relationship: part_of UBERON:0014477 ! thoracic skeleton relationship: part_of UBERON:0014478 ! rib skeletal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/88/Gray112.png" xsd:anyURI property_value: UBPROP:0000001 "Anatomical cluster that consists of more than one rib in an individual.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002100", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0003253 name: neck of rib namespace: uberon def: "The neck of the rib is the flattened portion which extends lateralward from the head; it is about 2.5 cm. long, and is placed in front of the transverse process of the lower of the two vertebrC& with which the head articulates. Its anterior surface is flat and smooth, its posterior rough for the attachment of the ligament of the neck, and perforated by numerous foramina. Of its two borders the superior presents a rough crest (crista colli costE) for the attachment of the anterior costotransverse ligament; its inferior border is rounded. On the posterior surface at the junction of the neck and body, and nearer the lower than the upper border, is an eminencebthe tubercle; it consists of an articular and a non-articular portion. The articular portion, the lower and more medial of the two, presents a small, oval surface for articulation with the end of the transverse process of the lower of the two vertebrC& to which the head is connected. The non-articular portion is a rough elevation, and affords attachment to the ligament of the tubercle. The tubercle is much more prominent in the upper than in the lower ribs." [Wikipedia:Neck_of_rib] synonym: "collum costae" EXACT LATIN [Wikipedia:Neck_of_rib] synonym: "collum costae" RELATED LATIN [Wikipedia:Neck_of_rib] synonym: "rib neck" EXACT [FMA:7576] xref: EMAPA:37826 {source="MA:th"} xref: FMA:7576 xref: SCTID:263359009 xref: Wikipedia:Neck_of_rib is_a: UBERON:0018664 ! neck of bone element intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0002228 ! rib relationship: part_of UBERON:0010388 {source="PMID:15906248"} ! proximal segment of rib property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray122.png" xsd:anyURI [Term] id: UBERON:0003257 name: yolk sac endoderm namespace: uberon def: "The portion of the yolk sac that is derived from endoderm and lines the yolk sac." [UBERON:cjm] xref: EHDAA2:0002215 xref: EHDAA:166 xref: EMAPA:16086 xref: VHOG:0000626 is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure is_a: UBERON:0005292 ! extraembryonic tissue is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: bounding_layer_of UBERON:0001040 ! yolk sac intersection_of: develops_from UBERON:0000925 ! endoderm relationship: bounding_layer_of UBERON:0001040 ! yolk sac relationship: part_of UBERON:0001040 ! yolk sac [Term] id: UBERON:0003258 name: endoderm of foregut namespace: uberon def: "An endoderm that is part of a foregut [Automatically generated definition]." [OBOL:automatic] synonym: "foregut endoderm" EXACT [OBOL:automatic] xref: EHDAA2:0004568 xref: EHDAA:524 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0015833 ! foregut epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001041 ! foregut property_value: editor_note "TODO - check" xsd:string [Term] id: UBERON:0003259 name: endoderm of midgut namespace: uberon def: "An endoderm that is part of a midgut [Automatically generated definition]." [OBOL:automatic] synonym: "midgut endoderm" EXACT [OBOL:automatic] xref: EHDAA:987 xref: EMAPA:16257 xref: RETIRED_EHDAA2:0001194 xref: VHOG:0001080 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0003352 ! epithelium of midgut is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001045 ! midgut property_value: editor_note "TODO - check" xsd:string [Term] id: UBERON:0003260 name: endoderm of hindgut namespace: uberon def: "An endoderm that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "hindgut endoderm" EXACT [OBOL:automatic] xref: EHDAA:979 xref: RETIRED_EHDAA2:0000781 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0003353 ! epithelium of hindgut is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001046 ! hindgut property_value: editor_note "TODO - check" xsd:string [Term] id: UBERON:0003265 name: chorionic mesenchyme namespace: uberon alt_id: UBERON:0003423 def: "A mesenchyme that is part of a chorion." [OBOL:automatic] subset: human_reference_atlas synonym: "chorion mesenchyme" EXACT [OBOL:automatic] synonym: "chorion mesoderm" EXACT [RETIRED_EHDAA2:0000247] synonym: "chorionic mesenchyme" EXACT [EHDAA2:0003245] synonym: "mesenchyme of chorion" EXACT [] synonym: "mesenchyme of chorion (vertebrates)" EXACT [OBOL:automatic] xref: EHDAA2:0003245 xref: EHDAA:154 xref: EMAPA:16114 xref: EMAPA:16266 xref: RETIRED_EHDAA2:0000247 xref: VHOG:0000620 is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue is_a: UBERON:0010333 ! extraembryonic membrane mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: develops_from UBERON:0004871 {source="ISBN:0073040584"} ! somatic layer of lateral plate mesoderm relationship: part_of UBERON:0003124 ! chorion membrane property_value: editor_note "TODO - check" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003267 name: tooth of upper jaw namespace: uberon def: "A calcareous tooth that is part of the upper jaw region. In mammals, the upper jaw teeth are attached to the maxilla." [http://orcid.org/0000-0002-6601-2165] synonym: "maxillary tooth" NARROW [NCBITaxon:40674] synonym: "upper jaw tooth" EXACT [MA:0001909] xref: EHDAA:8045 xref: EMAPA:17938 xref: MA:0001909 xref: NCIT:C49792 xref: SCTID:422279005 xref: UMLS:C1710581 {source="ncithesaurus:Upper_Jaw_Tooth"} is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001091 ! calcareous tooth is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: attaches_to UBERON:0011597 ! bone of upper jaw relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0009680 ! set of upper jaw teeth property_value: editor_note "Note that we follow EHDAA2 and consider teeth part of the jaw skeleton" xsd:string [Term] id: UBERON:0003268 name: tooth of lower jaw namespace: uberon def: "A calcareous tooth that is part of the lower jaw region. In mammals, the lower jaw teeth are attached to the mandible (dentary)." [http://orcid.org/0000-0002-6601-2165] synonym: "calcareous tooth of lower jaw" EXACT [OBOL:automatic] synonym: "lower jaw calcareous tooth" EXACT [OBOL:automatic] synonym: "lower jaw dentine containing tooth" EXACT [OBOL:automatic] synonym: "lower jaw tooth" EXACT [OBOL:automatic] synonym: "lower jaw vertebrate tooth" EXACT [OBOL:automatic] synonym: "mandibular tooth" NARROW [NCBITaxon:40674] xref: EHDAA2:0001029 xref: EHDAA:8009 xref: EMAPA:17917 xref: FMA:321647 xref: MA:0001907 xref: NCIT:C49582 xref: SCTID:422032003 xref: UMLS:C1708757 {source="ncithesaurus:Lower_Jaw_Tooth"} is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001091 ! calcareous tooth is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: attaches_to UBERON:0004768 ! bone of lower jaw relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0009679 ! set of lower jaw teeth [Term] id: UBERON:0003269 name: skeletal muscle tissue of eye namespace: uberon def: "A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]." [OBOL:automatic] synonym: "eye skeletal muscle" EXACT [OBOL:automatic] synonym: "eye skeletal muscle group" RELATED [EHDAA2:0000486] synonym: "eye skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of eye" EXACT [OBOL:automatic] xref: EHDAA2:0000486 xref: EHDAA:2923 xref: EMAPA:17844 is_a: UBERON:0001134 ! skeletal muscle tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0003277 name: skeleton of upper jaw namespace: uberon def: "A subdivision of the skeleton that corresponds to the upper part of the mouth. The lower jaw skeleton includes the following elements, when present: upper jaw teeth, the maxilla and other lower jaw bones." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "upper jaw" BROAD [MA:0001908] synonym: "upper jaw skeleton" EXACT [] xref: AAO:0000622 xref: EHDAA2:0002128 xref: EHDAA:8041 xref: EMAPA:17927 xref: FMA:54397 xref: MA:0001908 xref: VHOG:0000429 xref: XAO:0003087 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0001708 ! jaw skeleton relationship: part_of UBERON:0001709 ! upper jaw region relationship: skeleton_of UBERON:0001709 ! upper jaw region property_value: UBPROP:0000003 "The jaw joint of all jawed vertebrates, except for mammals, involves the quadrate and articular bones, or the posterior ends of the palatoquadrate and mandibular cartilages; A correlate of the conversion of the articular and quadrate bones to the malleus and incus is that all adult mammals have a jaw joint that lies between the dentary of the lower jaw and the squamosal bone of the skull roof.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000429", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.241 and p.101", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "EMAPA/MA placement unclear. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/102" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0003278 name: skeleton of lower jaw namespace: uberon def: "A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "lower jaw" BROAD [MA:0001906, ZFA:0001273] synonym: "lower jaw skeleton" EXACT [AAO:0000274] synonym: "mandible" BROAD [ZFA:0001273] synonym: "mandibles" RELATED PLURAL [TAO:0001273] synonym: "mandibular series" RELATED [ZFA:0001273] xref: AAO:0000274 xref: EHDAA2:0004606 xref: EHDAA:8005 xref: EMAPA:17906 xref: EMAPA:17910 xref: FMA:54398 xref: MA:0001906 xref: TAO:0001273 xref: VHOG:0000428 xref: XAO:0003084 xref: ZFA:0001273 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0001710 ! lower jaw region relationship: overlaps UBERON:0008895 {source="VHOG-modified"} ! splanchnocranium relationship: part_of UBERON:0001708 ! jaw skeleton relationship: part_of UBERON:0001710 {source="EHDAA2"} ! lower jaw region relationship: skeleton_of UBERON:0001710 ! lower jaw region property_value: UBPROP:0000001 "The ventral portion of the first pharyngeal arch, comprising the lower jaw.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001273", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "The jaw joint of all jawed vertebrates, except for mammals, involves the quadrate and articular bones, or the posterior ends of the palatoquadrate and mandibular cartilages; A correlate of the conversion of the articular and quadrate bones to the malleus and incus is that all adult mammals have a jaw joint that lies between the dentary of the lower jaw and the squamosal bone of the skull roof.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000428", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.241 and p.101", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "Inclusion of the FMA class 'lower jaw' is debatable - this mostly corresponds to the lower jaw skeleton (with 'maxillary part of mouth' corresponding to the upper jaw region); however, the FMA class also includes gingiva. See also: https://github.com/obophenotype/mouse-anatomy-ontology/issues/102" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003279 name: endothelium of trachea namespace: uberon def: "An endothelium that is part of a trachea." [OBOL:automatic] synonym: "endothelium of windpipe" EXACT [OBOL:automatic] synonym: "trachea endothelium" EXACT [OBOL:automatic] synonym: "windpipe endothelium" EXACT [OBOL:automatic] xref: EHDAA:3082 xref: RETIRED_EHDAA2:0002068 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0001901 ! epithelium of trachea is_a: UBERON:0001986 ! endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0003126 ! trachea [Term] id: UBERON:0003281 name: mesentery of stomach namespace: uberon def: "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum." [http://medical-dictionary.thefreedictionary.com/mesogastrium] subset: pheno_slim synonym: "mesentery of ventriculus" EXACT [OBOL:automatic] synonym: "mesogaster" EXACT [http://medical-dictionary.thefreedictionary.com/mesogastrium] synonym: "mesogastium" EXACT [MA:0001617] synonym: "mesogastrium" EXACT [http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html] synonym: "stomach mesentery" EXACT [Obol:obol] synonym: "ventriculus mesentery" EXACT [OBOL:automatic] xref: EHDAA2:0001922 xref: EHDAA:2999 xref: EMAPA:17024 xref: MA:0001617 xref: SCTID:261623000 xref: VHOG:0000358 is_a: UBERON:0004854 {source="MA"} ! gastrointestinal system mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0000945 ! stomach relationship: contributes_to_morphology_of UBERON:0000945 ! stomach relationship: part_of UBERON:0000945 {source="MA"} ! stomach property_value: editor_note "TODO - check primitive vs developed" xsd:string property_value: UBPROP:0000001 "The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000358", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesogastrium"} [Term] id: UBERON:0003282 name: mesentery of heart namespace: uberon def: "A mesentery that surrounds the heart." [MA:th] synonym: "cardiac mesentery" RELATED [EMAPA:16212] synonym: "heart mesentery" EXACT [OBOL:automatic] synonym: "mesocardium" RELATED [MA:0000098] xref: EHDAA:432 xref: EMAPA:16212 xref: RETIRED_EHDAA2:0000739 xref: VHOG:0000353 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart [Term] id: UBERON:0003283 name: mesentery of oesophagus namespace: uberon def: "A mesentery that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophagus mesentery" EXACT [MA:0001569] synonym: "gullet mesentery" EXACT [OBOL:automatic] synonym: "mesentery of esophagus" EXACT [OBOL:automatic] synonym: "mesentery of gullet" EXACT [OBOL:automatic] synonym: "meso-esophagus" EXACT [] synonym: "oesophagus mesentery" EXACT [VHOG:0000415] xref: EHDAA2:0001288 xref: EHDAA:2943 xref: EMAPA:16836 xref: MA:0001569 xref: VHOG:0000415 is_a: UBERON:0001975 ! serosa of esophagus is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001043 ! esophagus property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000415", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003284 name: mesentery of midgut namespace: uberon def: "A mesentery that is part of a midgut [Automatically generated definition]." [OBOL:automatic] synonym: "midgut mesentery" EXACT [OBOL:automatic] xref: EHDAA2:0001202 xref: EHDAA:3031 xref: EMAPA:16721 xref: EMAPA:17039 xref: EMAPA:17197 xref: VHOG:0000413 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001045 ! midgut relationship: part_of UBERON:0001045 ! midgut property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000413", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003288 name: meninx of midbrain namespace: uberon def: "A meninx that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "meninges of midbrain" EXACT PLURAL [OBOL:automatic] synonym: "mesencephalon meninges" RELATED PLURAL [VHOG:0000012] synonym: "midbrain meninges" EXACT PLURAL [OBOL:automatic] synonym: "midbrain meninx" EXACT [OBOL:automatic] xref: EHDAA2:0001174 xref: EHDAA:3708 xref: EMAPA:17791 xref: MA:0001058 xref: RETIRED_EHDAA2:0001109 xref: VHOG:0000012 is_a: UBERON:0003547 ! brain meninx intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0001891 ! midbrain property_value: editor_note "consider changing genus to subdivision of meninx" xsd:string property_value: UBPROP:0000001 "Meninges that are part of the midbrain. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000012", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000012", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003289 name: meninx of telencephalon namespace: uberon def: "A meninx that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "meninges of telencephalon" EXACT PLURAL [OBOL:automatic] synonym: "telencephalon meninges" EXACT PLURAL [OBOL:automatic] synonym: "telencephalon meninx" EXACT [OBOL:automatic] xref: EHDAA2:0001990 xref: EHDAA:5476 xref: EMAPA:17774 xref: MA:0000979 xref: VHOG:0000010 is_a: UBERON:0003548 ! forebrain meninges intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0001893 ! telencephalon property_value: editor_note "consider changing genus to subdivision of meninx" xsd:string property_value: UBPROP:0000001 "Meninges that are part of the telencephalon. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000010", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000010", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003291 name: meninx of hindbrain namespace: uberon def: "A meninx that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] synonym: "hindbrain meninges" EXACT [OBOL:automatic] synonym: "hindbrain meninx" EXACT [OBOL:automatic] synonym: "meninges of hindbrain" EXACT [OBOL:automatic] synonym: "rhomencephalon meninges" RELATED PLURAL [VHOG:0000011] xref: EHDAA2:0000770 xref: EHDAA:3688 xref: EMAPA:17783 xref: MA:0000987 xref: VHOG:0000011 is_a: UBERON:0003547 ! brain meninx intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0002028 ! hindbrain relationship: develops_from UBERON:0010091 ! future hindbrain meninx relationship: immediate_transformation_of UBERON:0010091 {evidence="definitional"} ! future hindbrain meninx relationship: part_of UBERON:0002028 ! hindbrain property_value: editor_note "consider changing genus to subdivision of meninx" xsd:string property_value: UBPROP:0000001 "Meninges that are part of the hindbrain. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000011", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000011", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003292 name: meninx of spinal cord namespace: uberon def: "A meninx that is part of a spinal cord [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "menines of spinal cord" EXACT PLURAL [] synonym: "meninges of spinal cord" EXACT [OBOL:automatic] synonym: "spinal cord meninges" EXACT [OBOL:automatic] synonym: "spinal cord meninx" EXACT [OBOL:automatic] synonym: "spinal meninges" EXACT PLURAL [] synonym: "spinal meninx" EXACT [] xref: CALOHA:TS-2148 xref: EHDAA2:0001895 xref: EHDAA:2865 xref: EMAPA:17804 xref: MA:0001130 xref: NCIT:C12350 xref: SCTID:181097002 xref: UMLS:C0037938 {source="ncithesaurus:Spinal_Meninges"} xref: VHOG:0000443 is_a: UBERON:0002360 ! meninx is_a: UBERON:0005174 ! dorsal region element intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord property_value: UBPROP:0000001 "Meninges that are part of the spinal cord. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000443", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000443", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003294 name: gland of foregut namespace: uberon def: "A gland that is part of a foregut [Automatically generated definition]." [OBOL:automatic] synonym: "foregut gland" EXACT [OBOL:automatic] xref: EHDAA2:0000567 xref: EHDAA:950 xref: EMAPA:16557 xref: VHOG:0000650 is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001041 ! foregut relationship: part_of UBERON:0001041 ! foregut [Term] id: UBERON:0003295 name: pharyngeal gland namespace: uberon def: "Racemose mucous glands beneath the mucous membrane of the pharynx." [http://www.biology-online.org/dictionary/] subset: organ_slim synonym: "glandulae pharyngeae" RELATED [BTO:0004849] synonym: "pharynx gland" EXACT [EHDAA2:0001461] xref: BTO:0004849 xref: EHDAA2:0001461 xref: EHDAA:2967 xref: FMA:55075 is_a: UBERON:0003408 ! gland of digestive tract is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 {source="BTO"} ! chordate pharynx [Term] id: UBERON:0003297 name: gland of integumental system namespace: uberon def: "A gland that is part of a integumental system [Automatically generated definition]." [OBOL:automatic] synonym: "integumental gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "integumental system gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "integumentary gland" EXACT [http://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0000837 xref: EHDAA:6522 xref: EMAPA:17758 xref: MA:0000144 xref: VHOG:0000654 is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002416 ! integumental system relationship: part_of UBERON:0002416 ! integumental system [Term] id: UBERON:0003304 name: mesoderm blood island namespace: uberon alt_id: UBERON:0003305 def: "A blood island that is part of a mesoderm." [OBOL:automatic] synonym: "mesenchyme blood island" RELATED [OBOL:automatic] synonym: "mesoderm blood islands" EXACT PLURAL [EHDAA2:0003241] xref: EHDAA2:0003241 xref: EHDAA:170 xref: EMAPA:16115 is_a: UBERON:0003061 ! blood island is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0003061 ! blood island intersection_of: part_of UBERON:0000926 ! mesoderm relationship: part_of UBERON:0000926 ! mesoderm relationship: part_of UBERON:0007798 {source="EHDAA2"} ! vascular system property_value: UBPROP:0000012 "in EHDAA2, gives rise to blood and dorsal aorta" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0003312 name: mesenchyme of testis namespace: uberon def: "Mesenchyme that is part of a developing testis [Automatically generated definition]." [OBOL:automatic] synonym: "testis mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0002010 xref: EHDAA:8150 xref: EMAPA:35858 xref: VHOG:0001442 is_a: UBERON:0003855 ! gonad mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000473 ! testis relationship: part_of UBERON:0000473 ! testis [Term] id: UBERON:0003314 name: eye mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing camera-type eye." [OBOL:automatic] synonym: "mesenchyme of eye" EXACT [OBOL:automatic] xref: EHDAA2:0000485 xref: EHDAA:2910 xref: EMAPA:16673 xref: VHOG:0001084 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest is_a: UBERON:0009891 ! facial mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: develops_from UBERON:0009920 {source="EHDAA2"} ! optic neural crest relationship: part_of UBERON:0000019 ! camera-type eye property_value: editor_note "TODO - change mesenchyme relationships to precursor_of" xsd:string [Term] id: UBERON:0003315 name: mesenchyme of ovary namespace: uberon def: "Mesenchyme that is part of a developing ovary [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "female reproductive system gonad mesenchyme" EXACT [OBOL:automatic] synonym: "female reproductive system gonada mesenchyme" EXACT [OBOL:automatic] synonym: "gonad of female reproductive system mesenchyme" EXACT [OBOL:automatic] synonym: "gonada of female reproductive system mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of female reproductive system gonad" EXACT [OBOL:automatic] synonym: "mesenchyme of female reproductive system gonada" EXACT [OBOL:automatic] synonym: "mesenchyme of gonad of female reproductive system" EXACT [OBOL:automatic] synonym: "mesenchyme of gonada of female reproductive system" EXACT [OBOL:automatic] synonym: "ovary mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0001362 xref: EHDAA:8128 xref: VHOG:0001441 is_a: UBERON:0003855 ! gonad mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0000992 ! ovary property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003316 name: mesenchyme of yolk sac namespace: uberon alt_id: UBERON:0003264 def: "The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme." [UBERON:cjm] synonym: "yolk sac mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0002216 xref: EHDAA:168 xref: EHDAA:205 xref: EMAPA:16087 xref: EMAPA:16267 xref: VHOG:0000503 xref: VHOG:0000617 is_a: UBERON:0010333 ! extraembryonic membrane mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001040 ! yolk sac relationship: part_of UBERON:0001040 ! yolk sac [Term] id: UBERON:0003317 name: odontogenic papilla of incisor namespace: uberon def: "An odontogenic papilla that is part of a incisor tooth [Automatically generated definition]." [OBOL:automatic] synonym: "incisor dental papilla" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "incisor odontogenic papilla" EXACT [OBOL:automatic] synonym: "incisor tooth odontogenic papilla" EXACT [OBOL:automatic] synonym: "odontogenic papilla of incisor tooth" EXACT [OBOL:automatic] xref: EMAPA:32893 xref: MA:0003231 is_a: UBERON:0001763 ! odontogenic papilla intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0001098 ! incisor tooth relationship: develops_from UBERON:0015846 ! incisor mesenchyme relationship: part_of UBERON:0001098 ! incisor tooth [Term] id: UBERON:0003318 name: mesenchyme of elbow namespace: uberon def: "Mesenchyme that is part of a developing elbow [Automatically generated definition]." [OBOL:automatic] synonym: "cubital region mesenchyme" EXACT [OBOL:automatic] synonym: "elbow mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of cubital region" EXACT [OBOL:automatic] xref: EHDAA2:0000432 xref: EHDAA:4170 xref: EHDAA:6216 xref: EMAPA:17416 xref: VHOG:0001075 is_a: UBERON:0003859 ! forelimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001461 ! elbow relationship: part_of UBERON:0001461 ! elbow [Term] id: UBERON:0003319 name: mesenchyme of carpal region namespace: uberon def: "Mesenchyme of the carpal region that contributes to the carpal skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "carpal region mesenchyme" EXACT [OBOL:automatic] synonym: "carpus mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of wrist" EXACT [OBOL:automatic] synonym: "wrist mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0000220 xref: EHDAA:5200 xref: EMAPA:19122 is_a: UBERON:0003859 ! forelimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004452 ! carpal region relationship: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0003320 name: mesenchyme of hip namespace: uberon def: "Mesenchyme that is part of a developing hip [Automatically generated definition]." [OBOL:automatic] synonym: "hip mesenchyme" EXACT [OBOL:automatic] synonym: "hip region mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of hip region" EXACT [OBOL:automatic] synonym: "mesenchyme of regio coxae" EXACT [OBOL:automatic] synonym: "regio coxae mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0000786 xref: EHDAA:5157 xref: EHDAA:6182 xref: EMAPA:17492 xref: VHOG:0001029 is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001464 ! hip relationship: part_of UBERON:0001464 ! hip [Term] id: UBERON:0003321 name: mesenchyme of knee namespace: uberon def: "Mesenchyme that is part of a developing knee [Automatically generated definition]." [OBOL:automatic] synonym: "knee mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0000898 xref: EHDAA:5163 xref: EHDAA:6188 xref: EMAPA:17495 xref: VHOG:0001070 is_a: UBERON:0003860 ! hindlimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001465 ! knee relationship: part_of UBERON:0001465 ! knee [Term] id: UBERON:0003322 name: mesenchyme of shoulder namespace: uberon def: "Mesenchyme that is part of a developing shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "shoulder mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0001837 xref: EHDAA:4184 xref: EHDAA:6232 xref: EMAPA:17423 xref: VHOG:0001035 is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001467 ! shoulder relationship: part_of UBERON:0001467 ! shoulder [Term] id: UBERON:0003323 name: mesenchyme of upper jaw namespace: uberon def: "Mesenchyme that is part of a developing upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyme of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "palatoquadrate arch mesenchyme" EXACT [OBOL:automatic] synonym: "upper jaw mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0002124 xref: EHDAA:8031 xref: EMAPA:17929 xref: VHOG:0001099 is_a: UBERON:0009891 ! facial mesenchyme is_a: UBERON:0034995 ! jaw mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: develops_from UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme relationship: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0003324 name: mesenchyme of lower jaw namespace: uberon def: "Mesenchyme that is part of a developing lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "lower jaw mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "ventral mandibular arch mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0001024 xref: EHDAA:8003 xref: EMAPA:17916 xref: VHOG:0001069 is_a: UBERON:0034995 ! jaw mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: develops_from UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme relationship: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0003325 name: mesenchyme of pinna namespace: uberon def: "Mesenchyme that is part of a developing pinna [Automatically generated definition]." [OBOL:automatic] synonym: "auricle mesenchyme" EXACT [OBOL:automatic] synonym: "auricle of ear mesenchyme" EXACT [OBOL:automatic] synonym: "auricle of external ear mesenchyme" EXACT [OBOL:automatic] synonym: "auricula (auris externa) mesenchyme" EXACT [OBOL:automatic] synonym: "auricula mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of auricle" EXACT [OBOL:automatic] synonym: "mesenchyme of auricle of ear" EXACT [OBOL:automatic] synonym: "mesenchyme of auricle of external ear" EXACT [OBOL:automatic] synonym: "mesenchyme of auricula" EXACT [OBOL:automatic] synonym: "mesenchyme of auricula (auris externa)" EXACT [OBOL:automatic] synonym: "mesenchyme of pinna of ear" EXACT [OBOL:automatic] synonym: "pinna mesenchyme" EXACT [OBOL:automatic] synonym: "pinna of ear mesenchyme" EXACT [OBOL:automatic] xref: EHDAA2:0001469 xref: EHDAA:8981 xref: EMAPA:17591 xref: VHOG:0000747 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005253 ! head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001757 ! pinna relationship: part_of UBERON:0001757 ! pinna property_value: UBPROP:0000012 "EMAPA divides this spatially into condensation + rest, and temporally into mesenchyme and cartilage condensation" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0003327 name: mesenchyme of forearm namespace: uberon def: "Mesenchyme that is part of a developing lower arm [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0000555 xref: EHDAA:4176 xref: EHDAA:6222 xref: EMAPA:17419 xref: VHOG:0000504 is_a: UBERON:0003859 ! forelimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0002386 ! forelimb zeugopod [Term] id: UBERON:0003328 name: mesenchyme of footplate namespace: uberon alt_id: UBERON:0005260 def: "Mesenchyme that is part of a footplate." [OBOL:automatic] synonym: "foot plate mesenchyme" EXACT [] xref: EHDAA2:0000549 xref: EHDAA:5149 xref: EHDAA:6172 xref: EMAPA:17252 xref: EMAPA:17488 xref: VHOG_RETIRED:0001055 is_a: UBERON:0010377 ! mesenchyme from somatopleure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006871 ! embryonic footplate relationship: develops_from UBERON:0003412 {source="EHDAA2"} ! pelvic appendage bud mesenchyme relationship: part_of UBERON:0006871 ! embryonic footplate property_value: UBPROP:0000012 "We group two EMAPA classes here but these may need to be separated" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0003329 name: submucosa of anal canal namespace: uberon def: "A submucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "anal canal submucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically submucosa" EXACT [OBOL:automatic] synonym: "anal region submucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal submucosa" EXACT [OBOL:automatic] synonym: "submucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "submucosa of anal region" EXACT [OBOL:automatic] synonym: "submucosa of anatomical anal canal" EXACT [OBOL:automatic] xref: EMAPA:27217 xref: EMAPA:27227 xref: EMAPA:27535 xref: FMA:85399 xref: SCTID:7892006 is_a: UBERON:0001208 ! submucosa of large intestine is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000159 ! anal canal relationship: part_of UBERON:0000159 ! anal canal property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003330 name: submucosa of rectum namespace: uberon def: "The submucous layer of the wall of the rectum." [BTO:0002114] synonym: "rectal submucosa" EXACT [FMA:15034] synonym: "rectum submucosa" EXACT [OBOL:automatic] synonym: "tela submucosa recti" EXACT LATIN [BTO:0002114] xref: BTO:0002114 xref: EMAPA:27083 xref: FMA:15034 xref: SCTID:71683001 is_a: UBERON:0001208 ! submucosa of large intestine intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003331 name: submucosa of colon namespace: uberon def: "A submucosa that is part of a colon [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "colon submucosa" EXACT [OBOL:automatic] synonym: "colonic submucosa" EXACT [FMA:14985] synonym: "large bowel submucosa" EXACT [OBOL:automatic] synonym: "submucosa of large bowel" EXACT [OBOL:automatic] xref: EMAPA:27379 xref: FMA:14985 xref: MA:0003200 xref: SCTID:61647009 is_a: UBERON:0001208 ! submucosa of large intestine intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003332 name: submucosa of duodenum namespace: uberon def: "A submucosa that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "doudenal submucosa" EXACT [FMA:14943] synonym: "duodenal submucosa" EXACT [FMA:14943] synonym: "duodenum submucosa" EXACT [OBOL:automatic] xref: EMAPA:27027 xref: EMAPA:27097 xref: EMAPA:27239 xref: FMA:14943 xref: MA:0003213 xref: SCTID:76519004 is_a: UBERON:0001205 ! submucosa of small intestine intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003334 name: serosa of rectum namespace: uberon def: "A serous membrane that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "rectal serosa" EXACT [FMA:15039] synonym: "rectum serosa" EXACT [OBOL:automatic] synonym: "rectum serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of rectum" EXACT [OBOL:automatic] synonym: "visceral peritoneum of rectum" EXACT [FMA:15039] xref: EMAPA:27087 xref: FMA:15039 is_a: UBERON:0001209 ! serosa of large intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003335 name: serosa of colon namespace: uberon def: "A serous membrane that is part of a colon [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "colon serosa" EXACT [OBOL:automatic] synonym: "colon serous membrane" EXACT [OBOL:automatic] synonym: "colonic serosa" EXACT [FMA:14990] synonym: "large bowel serosa" EXACT [OBOL:automatic] synonym: "large bowel serous membrane" EXACT [OBOL:automatic] synonym: "serosa of large bowel" EXACT [OBOL:automatic] synonym: "serous membrane of colon" EXACT [OBOL:automatic] synonym: "serous membrane of large bowel" EXACT [OBOL:automatic] synonym: "visceral peritoneum of colon" EXACT [FMA:14990] xref: EMAPA:27387 xref: FMA:14990 xref: MA:0003199 xref: SCTID:90132000 is_a: UBERON:0001209 ! serosa of large intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003336 name: serosa of duodenum namespace: uberon def: "A serous membrane that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "doudenal serosa" EXACT [FMA:14948] synonym: "duodenal serosa" EXACT [FMA:14948] synonym: "duodenum serosa" EXACT [OBOL:automatic] synonym: "duodenum serous membrane" EXACT [OBOL:automatic] synonym: "serous membrane of duodenum" EXACT [OBOL:automatic] synonym: "visceral peritoneum of duodenum" EXACT [FMA:14948] xref: EMAPA:27247 xref: FMA:14948 xref: MA:0003212 xref: SCTID:1236009 is_a: UBERON:0001206 ! serosa of small intestine intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000010 "1st part serosa, 2nd - 4th adventitia" xsd:string [Term] id: UBERON:0003338 name: ganglion of peripheral nervous system namespace: uberon def: "A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO)." [BIRNLEX:2548] subset: cumbo synonym: "peripheral nervous system ganglion" EXACT [OBOL:automatic] xref: BIRNLEX:2548 xref: BTO:0001123 xref: EMAPA:32814 xref: MA:0001161 is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0000010 ! peripheral nervous system relationship: part_of UBERON:0000010 ! peripheral nervous system property_value: UBPROP:0000012 "we follow MA in including separate classes for ganglion and peripheral nervous system, even though for vertebrates gangia are always in the PNS" xsd:string {external_ontology="MA"} [Term] id: UBERON:0003339 name: ganglion of central nervous system namespace: uberon def: "A ganglion that is part of a central nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "central nervous system ganglion" EXACT [OBOL:automatic] synonym: "ganglion of neuraxis" EXACT [OBOL:automatic] synonym: "neuraxis ganglion" EXACT [OBOL:automatic] xref: EHDAA2:0000227 xref: EMAPA:16658 xref: FMA:83843 is_a: UBERON:0000045 ! ganglion is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0001017 ! central nervous system relationship: part_of UBERON:0001017 ! central nervous system property_value: UBPROP:0000012 "this has no subclasses in FMA. In EHDAA2 and EMAPA it has only the cranial ganglia" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003342 name: mucosa of anal canal namespace: uberon def: "A mucosa that is part of an anal canal [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "anal canal mucosa" EXACT [OBOL:automatic] synonym: "anal canal mucosa of organ" EXACT [OBOL:automatic] synonym: "anal canal mucous membrane" EXACT [OBOL:automatic] synonym: "anal canal organ mucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucosa" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucosa of organ" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically mucous membrane" EXACT [OBOL:automatic] synonym: "anal canal viewed anatomically organ mucosa" EXACT [OBOL:automatic] synonym: "anal mucosa" EXACT [FMA:74654] synonym: "anal mucous membrane" EXACT [FMA:74654] synonym: "anal region mucosa" EXACT [OBOL:automatic] synonym: "anal region mucosa of organ" EXACT [OBOL:automatic] synonym: "anal region mucous membrane" EXACT [OBOL:automatic] synonym: "anal region organ mucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucosa" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucosa of organ" EXACT [OBOL:automatic] synonym: "anatomical anal canal mucous membrane" EXACT [OBOL:automatic] synonym: "anatomical anal canal organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucosa of anal region" EXACT [OBOL:automatic] synonym: "mucosa of anatomical anal canal" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal canal" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucosa of organ of anal region" EXACT [OBOL:automatic] synonym: "mucosa of organ of anatomical anal canal" EXACT [OBOL:automatic] synonym: "mucous membrane of anal canal" EXACT [OBOL:automatic] synonym: "mucous membrane of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "mucous membrane of anal region" EXACT [OBOL:automatic] synonym: "mucous membrane of anatomical anal canal" EXACT [OBOL:automatic] synonym: "organ mucosa of anal canal" EXACT [OBOL:automatic] synonym: "organ mucosa of anal canal viewed anatomically" EXACT [OBOL:automatic] synonym: "organ mucosa of anal region" EXACT [OBOL:automatic] synonym: "organ mucosa of anatomical anal canal" EXACT [OBOL:automatic] xref: EMAPA:27531 xref: FMA:74654 xref: NCIT:C60784 xref: SCTID:362170004 xref: UMLS:C0227414 {source="ncithesaurus:Anal_Mucosa"} is_a: UBERON:0001207 ! mucosa of large intestine is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000159 ! anal canal relationship: part_of UBERON:0000159 ! anal canal property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003343 name: mucosa of oral region namespace: uberon def: "A mucosa that is part of a oral opening [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of oral opening" EXACT [OBOL:automatic] synonym: "mucosa of oral part of face" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral opening" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral part of face" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral region" EXACT [OBOL:automatic] synonym: "mucosa of organ of subdivision of mouth" EXACT [OBOL:automatic] synonym: "mucosa of subdivision of mouth" EXACT [OBOL:automatic] synonym: "mucous membrane of oral opening" EXACT [OBOL:automatic] synonym: "mucous membrane of oral part of face" EXACT [OBOL:automatic] synonym: "mucous membrane of oral region" EXACT [OBOL:automatic] synonym: "mucous membrane of subdivision of mouth" EXACT [OBOL:automatic] synonym: "oral opening mucosa" EXACT [OBOL:automatic] synonym: "oral opening mucosa of organ" EXACT [OBOL:automatic] synonym: "oral opening mucous membrane" EXACT [OBOL:automatic] synonym: "oral opening organ mucosa" EXACT [OBOL:automatic] synonym: "oral part of face mucosa" EXACT [OBOL:automatic] synonym: "oral part of face mucosa of organ" EXACT [OBOL:automatic] synonym: "oral part of face mucous membrane" EXACT [OBOL:automatic] synonym: "oral part of face organ mucosa" EXACT [OBOL:automatic] synonym: "oral region mucosa" EXACT [OBOL:automatic] synonym: "oral region mucosa of organ" EXACT [OBOL:automatic] synonym: "oral region mucous membrane" EXACT [OBOL:automatic] synonym: "oral region organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of oral opening" EXACT [OBOL:automatic] synonym: "organ mucosa of oral part of face" EXACT [OBOL:automatic] synonym: "organ mucosa of oral region" EXACT [OBOL:automatic] synonym: "organ mucosa of subdivision of mouth" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucosa" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucosa of organ" EXACT [OBOL:automatic] synonym: "subdivision of mouth mucous membrane" EXACT [OBOL:automatic] synonym: "subdivision of mouth organ mucosa" EXACT [OBOL:automatic] xref: EMAPA:26937 xref: SCTID:362083000 is_a: UBERON:0003729 ! mouth mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000166 ! oral opening relationship: part_of UBERON:0000166 ! oral opening [Term] id: UBERON:0003346 name: mucosa of rectum namespace: uberon def: "A mucosa that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of rectum" EXACT [OBOL:automatic] synonym: "mucous membrane of rectum" EXACT [OBOL:automatic] synonym: "organ mucosa of rectum" EXACT [OBOL:automatic] synonym: "rectal mucosa" EXACT [FMA:15033] synonym: "rectal mucous membrane" EXACT [FMA:15033] synonym: "rectum mucosa" EXACT [OBOL:automatic] synonym: "rectum mucosa of organ" EXACT [OBOL:automatic] synonym: "rectum mucous membrane" EXACT [OBOL:automatic] synonym: "rectum organ mucosa" EXACT [OBOL:automatic] xref: CALOHA:TS-2107 xref: EMAPA:27081 xref: FMA:15033 xref: MA:0003218 xref: SCTID:362167003 is_a: UBERON:0001207 ! mucosa of large intestine intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003350 name: epithelium of mucosa namespace: uberon def: "A layer of epithelial cells on the surface of the mucosa." [BTO:0003752] comment: lies on top of lamina propria synonym: "lamina epithelialis mucosa" RELATED [BTO:0003752] synonym: "lamina epithelialis mucosae" RELATED [BTO:0003752] xref: BTO:0003752 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000344 ! mucosa relationship: part_of UBERON:0000344 ! mucosa [Term] id: UBERON:0003351 name: pharyngeal epithelium namespace: uberon def: "An epithelium that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "epithelial tissue of pharynx" EXACT [OBOL:automatic] synonym: "epithelium of pharynx" EXACT [OBOL:automatic] synonym: "pharynx epithelial tissue" EXACT [OBOL:automatic] synonym: "pharynx epithelium" EXACT [OBOL:automatic] xref: BSA:0000112 xref: BTO:0005240 xref: EMAPA:16708 xref: MA:0002725 xref: RETIRED_EHDAA2:0001460 xref: TAO:0001174 xref: XAO:0003202 xref: ZFA:0001174 is_a: UBERON:0000490 {gci_relation="part_of", gci_filler="NCBITaxon:7955", source="ZFA"} ! unilaminar epithelium is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0004807 ! respiratory system epithelium is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: develops_from UBERON:0007690 {source="ZFA"} ! early pharyngeal endoderm relationship: part_of UBERON:0001042 {source="ZFA"} ! chordate pharynx property_value: UBPROP:0000001 "Epithelium lining the pharynx consisting largely of simple columnar epithelium with a short segment (1mm) of stratified squamous epithelium on the ventral side. Chen et al, 2007.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001174", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0003352 name: epithelium of midgut namespace: uberon def: "An epithelium that is part of a midgut." [OBOL:automatic] synonym: "epithelial tissue of midgut" EXACT [OBOL:automatic] synonym: "midgut epithelial tissue" EXACT [OBOL:automatic] synonym: "midgut epithelium" EXACT [BTO:0005053, OBOL:automatic] xref: BTO:0005053 xref: EHDAA2:0001195 xref: EMAPA:16569 xref: MA:0003205 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001045 ! midgut relationship: part_of UBERON:0001045 {source="BTO"} ! midgut [Term] id: UBERON:0003353 name: epithelium of hindgut namespace: uberon def: "An epithelium that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of hindgut" EXACT [OBOL:automatic] synonym: "hindgut epithelial tissue" EXACT [OBOL:automatic] synonym: "hindgut epithelium" EXACT [OBOL:automatic] xref: EHDAA2:0000782 xref: EMAPA:16717 xref: MA:0003206 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001046 ! hindgut relationship: part_of UBERON:0001046 ! hindgut [Term] id: UBERON:0003354 name: epithelium of rectum namespace: uberon def: "An epithelium that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of rectum" EXACT [OBOL:automatic] synonym: "rectal epithelium" EXACT [FMA:17510] synonym: "rectum epithelial tissue" EXACT [OBOL:automatic] synonym: "rectum epithelium" EXACT [OBOL:automatic] xref: CALOHA:TS-2066 xref: EHDAA2:0001594 xref: EMAPA:17898 xref: FMA:17510 xref: MA:0003219 xref: VHOG:0001037 is_a: UBERON:0001278 ! epithelium of large intestine is_a: UBERON:0016885 ! epithelium of terminal part of digestive tract intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003355 name: epithelium of incisor namespace: uberon def: "An epithelium that is part of a incisor tooth [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of incisor" EXACT [OBOL:automatic] synonym: "epithelial tissue of incisor tooth" EXACT [OBOL:automatic] synonym: "epithelium of incisor tooth" EXACT [OBOL:automatic] synonym: "incisor epithelial tissue" EXACT [OBOL:automatic] synonym: "incisor epithelium" EXACT [OBOL:automatic] synonym: "incisor tooth epithelial tissue" EXACT [OBOL:automatic] synonym: "incisor tooth epithelium" EXACT [OBOL:automatic] xref: EMAPA:32890 xref: MA:0003223 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001098 ! incisor tooth relationship: part_of UBERON:0001098 ! incisor tooth [Term] id: UBERON:0003357 name: epithelium of tongue namespace: uberon def: "An epithelium that is part of a tongue [Automatically generated definition]." [OBOL:automatic] comment: examples: tongue squamous epithelium, keratined, non-keratinized and parakeratinized epithelium, as well as gustatory epithelium. Note that not all these subtypes are named in individual anatomy ontologies. subset: pheno_slim synonym: "epithelial tissue of tongue" EXACT [OBOL:automatic] synonym: "lingual epithelium" RELATED [BTO:0000992] synonym: "tongue epithelial tissue" EXACT [OBOL:automatic] synonym: "tongue epithelium" EXACT [OBOL:automatic] xref: BTO:0000992 xref: CALOHA:TS-1051 xref: EHDAA2:0004598 xref: EMAPA:17881 xref: FMA:284658 xref: MA:0001592 xref: NCIT:C49300 xref: UMLS:C1710436 {source="ncithesaurus:Tongue_Epithelium"} is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0019304 ! sensory organ epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001723 ! tongue relationship: contributes_to_morphology_of UBERON:0001723 ! tongue relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0003364 name: epithelium of right lung namespace: uberon def: "An epithelium that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of right lung" EXACT [OBOL:automatic] synonym: "right lung epithelial tissue" EXACT [OBOL:automatic] synonym: "right lung epithelium" EXACT [OBOL:automatic] xref: EMAPA:17663 xref: MA:0003132 is_a: UBERON:0000115 ! lung epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002167 ! right lung relationship: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0003365 name: epithelium of left lung namespace: uberon def: "An epithelium that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of left lung" EXACT [OBOL:automatic] synonym: "left lung epithelial tissue" EXACT [OBOL:automatic] synonym: "left lung epithelium" EXACT [OBOL:automatic] xref: EMAPA:17655 xref: MA:0003131 is_a: UBERON:0000115 ! lung epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002168 ! left lung relationship: part_of UBERON:0002168 ! left lung [Term] id: UBERON:0003368 name: epithelium of hard palate namespace: uberon def: "An epithelium that is part of a hard palate [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of hard palate" EXACT [OBOL:automatic] synonym: "hard palate epithelial tissue" EXACT [OBOL:automatic] synonym: "hard palate epithelium" EXACT [OBOL:automatic] xref: EMAPA:18953 is_a: UBERON:0003235 ! epithelium of upper jaw is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003216 ! hard palate relationship: part_of UBERON:0003216 ! hard palate [Term] id: UBERON:0003371 name: pelvic appendage bud ectoderm namespace: uberon alt_id: UBERON:0005232 def: "An unilaminar epithelium that surrounds a pelvic appendage bud." [OBOL:automatic] synonym: "hindlimb bud ectoderm" NARROW SENSU [EMAPA:16780] synonym: "hindlimb ectoderm" EXACT [VHOG:0001048] synonym: "hindlimb ectoderm" NARROW SENSU [VHOG:0001048] synonym: "leg ectoderm" RELATED [OBOL:automatic] synonym: "lower limb bud ectoderm" NARROW SENSU [EHDAA2:0001034] synonym: "pelvic fin bud ectoderm" NARROW SENSU [] xref: EHDAA2:0001034 xref: EMAPA:16780 xref: VHOG:0001048 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: bounding_layer_of UBERON:0005420 ! pelvic appendage bud relationship: bounding_layer_of UBERON:0005420 ! pelvic appendage bud relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0005420 ! pelvic appendage bud [Term] id: UBERON:0003372 name: pectoral appendage bud ectoderm namespace: uberon alt_id: UBERON:0005231 alt_id: UBERON:0005663 def: "An unilaminar epithelium that surrounds a pectoral appendage bud." [OBOL:automatic] synonym: "arm ectoderm" RELATED [OBOL:automatic] synonym: "forelimb bud ectoderm" NARROW SENSU [EMAPA:16407] synonym: "forelimb ectoderm" NARROW SENSU [VHOG:0001047] synonym: "pectoral fin bud ectoderm" NARROW SENSU [] synonym: "upper limb bud ectoderm" NARROW SENSU [EHDAA2:0002134] synonym: "wing ectoderm" NARROW SENSU [Geisha:syn, NCBITaxon:8782] xref: EHDAA2:0002134 xref: EMAPA:16407 xref: VHOG:0001047 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: bounding_layer_of UBERON:0005419 ! pectoral appendage bud relationship: bounding_layer_of UBERON:0005419 ! pectoral appendage bud relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0005419 ! pectoral appendage bud [Term] id: UBERON:0003373 name: ectoderm of footplate namespace: uberon def: "An ectoderm that is part of a footplate." [OBOL:automatic] xref: EMAPA:17250 is_a: UBERON:0000924 ! ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0006871 ! embryonic footplate relationship: part_of UBERON:0006871 ! embryonic footplate [Term] id: UBERON:0003374 name: chorionic ectoderm namespace: uberon def: "An extraembryonic structure that develops_from a ectoderm and is part of a chorion." [OBOL:automatic] synonym: "chorion ectoderm" EXACT [OBOL:automatic] synonym: "chorion epithelium" RELATED [] synonym: "chorionic epithelium" RELATED [BTO:0005145] xref: BTO:0005145 xref: EMAPA:16113 is_a: UBERON:0000478 ! extraembryonic structure intersection_of: UBERON:0000478 ! extraembryonic structure intersection_of: develops_from UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0003124 ! chorion membrane relationship: develops_from UBERON:0000924 {source="ISBN:0073040584"} ! ectoderm relationship: part_of UBERON:0003124 ! chorion membrane [Term] id: UBERON:0003379 name: cardiac muscle of right atrium namespace: uberon def: "A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "cardiac muscle of cardiac right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of heart right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of right atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of right atrium of heart" EXACT [OBOL:automatic] synonym: "myocardium of right atrium" EXACT [] synonym: "right atrium heart muscle" EXACT [EHDAA2:0004155] synonym: "right atrium myocardium" EXACT [VHOG:0001227] synonym: "textus muscularis of myocardium of right atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of right atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of right cardiac atrium" EXACT [OBOL:automatic] xref: EHDAA2:0004155 xref: EMAPA:17326 xref: FMA:7282 xref: SCTID:362018002 xref: VHOG:0001227 is_a: UBERON:0004490 ! cardiac muscle tissue of atrium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002078 ! right cardiac atrium relationship: part_of UBERON:0002078 ! right cardiac atrium property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003380 name: cardiac muscle of left atrium namespace: uberon def: "A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac left atrium cardiac muscle" EXACT [OBOL:automatic] synonym: "cardiac left atrium cardiac muscle tissue" EXACT [OBOL:automatic] synonym: "cardiac muscle of cardiac left atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of heart left atrium" EXACT [OBOL:automatic] synonym: "cardiac muscle of left atrium of heart" EXACT [OBOL:automatic] synonym: "left atrium heart muscle" EXACT [EHDAA2:0004154] synonym: "left atrium myocardium" EXACT [VHOG:0001225] synonym: "myocardium of left atrium" EXACT [] synonym: "textus muscularis of myocardium of cardiac left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of heart left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left atrium" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left atrium of heart" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of left cardiac atrium" EXACT [OBOL:automatic] xref: EHDAA2:0004154 xref: EMAPA:17320 xref: FMA:7285 xref: SCTID:189936008 xref: VHOG:0001225 is_a: UBERON:0004490 ! cardiac muscle tissue of atrium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002079 ! left cardiac atrium relationship: part_of UBERON:0002079 ! left cardiac atrium [Term] id: UBERON:0003381 name: cardiac muscle of right ventricle namespace: uberon def: "A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle tissue of right ventricle" EXACT [FMA:83452] synonym: "right ventricle cardiac muscle" RELATED [VHOG:0001236] synonym: "right ventricular cardiac muscle tissue" EXACT [GO:0003221] xref: EMAPA:17342 xref: FMA:83452 xref: VHOG:0001236 is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0002080 ! heart right ventricle [Term] id: UBERON:0003382 name: cardiac muscle of left ventricle namespace: uberon def: "A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle tissue of left ventricle" EXACT [FMA:83453] synonym: "left ventricle cardiac muscle" RELATED [VHOG:0001234] synonym: "left ventricular cardiac muscle tissue" EXACT [GO:0003220] xref: EMAPA:17339 xref: FMA:83453 xref: VHOG:0001234 is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 ! heart left ventricle [Term] id: UBERON:0003383 name: cardiac muscle tissue of interventricular septum namespace: uberon def: "A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "cardiac muscle of interventricular septum" EXACT [] synonym: "cardiac muscle tissue of interventricular septum" EXACT [FMA:84084] synonym: "interventricular septum cardiac muscle" EXACT [VHOG:0000999] synonym: "interventricular septum heart muscle" EXACT [EHDAA2:0004158] synonym: "interventricular septum muscle" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "interventricular septum myocardium" EXACT [VHOG:0000999] xref: EHDAA2:0004158 xref: EMAPA:17335 xref: FMA:84084 xref: VHOG:0000999 is_a: UBERON:0004492 ! cardiac muscle tissue of cardiac septum is_a: UBERON:0004667 ! interventricular septum muscular part intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002094 ! interventricular septum property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003384 name: skeletal muscle tissue of pharynx namespace: uberon def: "A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]." [OBOL:automatic] synonym: "pharynx skeletal muscle" EXACT [OBOL:automatic] synonym: "pharynx skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of pharynx" EXACT [OBOL:automatic] xref: EMAPA:18963 is_a: UBERON:0004830 ! respiratory system skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 ! chordate pharynx [Term] id: UBERON:0003386 name: smooth muscle of eye namespace: uberon def: "Any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi." [MGI:cwg, MP:0005247] subset: pheno_slim synonym: "ocular smooth muscle" EXACT [MA:0001268] xref: EMAPA:18807 xref: MA:0001268 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: contributes_to_morphology_of UBERON:0001015 ! musculature relationship: part_of UBERON:0000019 ! camera-type eye property_value: editor_note "Not clear if we need this and intra-ocular muscle. See issue #331. MA includes ciliary and iris smooth muscle" xsd:string [Term] id: UBERON:0003387 name: smooth muscle of trachea namespace: uberon alt_id: UBERON:0004244 def: "A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "trachea smooth muscle" EXACT [MA:0001863] synonym: "tracheal smooth muscle" EXACT [BTO:0001391] xref: BTO:0001391 xref: EMAPA:19192 xref: FMA:262010 xref: MA:0001863 xref: NCIT:C49306 xref: UMLS:C1710458 {source="ncithesaurus:Trachea_Smooth_Muscle_Tissue"} is_a: UBERON:0004233 ! lower respiratory tract smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003126 ! trachea relationship: contributes_to_morphology_of UBERON:0003126 ! trachea relationship: part_of UBERON:0003126 ! trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003388 name: mesothelium of pericardial cavity namespace: uberon def: "A mesothelium that is part of a pericardium [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of pericardial sac meso-epithelium" EXACT [OBOL:automatic] synonym: "cavity of pericardial sac mesothelium" EXACT [OBOL:automatic] synonym: "meso-epithelium of cavity of pericardial sac" EXACT [OBOL:automatic] synonym: "meso-epithelium of pericardial cavity" EXACT [OBOL:automatic] synonym: "mesothelium of cavity of pericardial sac" EXACT [OBOL:automatic] synonym: "pericardial cavity meso-epithelium" EXACT [OBOL:automatic] synonym: "pericardial cavity mesothelium" EXACT [OBOL:automatic] xref: RETIRED_EHDAA2:0001436 is_a: UBERON:0001136 ! mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0002407 ! pericardium relationship: part_of UBERON:0002407 ! pericardium [Term] id: UBERON:0003389 name: mesothelium of diaphragm namespace: uberon def: "A mesothelium that is part of a diaphragm [Automatically generated definition]." [OBOL:automatic] synonym: "diaphragm meso-epithelium" EXACT [OBOL:automatic] synonym: "diaphragm mesothelium" EXACT [OBOL:automatic] synonym: "meso-epithelium of diaphragm" EXACT [OBOL:automatic] synonym: "meso-epithelium of thoracic diaphragm" EXACT [OBOL:automatic] synonym: "mesothelium of thoracic diaphragm" EXACT [OBOL:automatic] synonym: "thoracic diaphragm meso-epithelium" EXACT [OBOL:automatic] synonym: "thoracic diaphragm mesothelium" EXACT [OBOL:automatic] xref: EMAPA:18429 is_a: UBERON:0001136 ! mesothelium is_a: UBERON:0004807 ! respiratory system epithelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0001103 ! diaphragm relationship: part_of UBERON:0001103 ! diaphragm [Term] id: UBERON:0003390 name: mesothelium of pleural cavity namespace: uberon def: "A mesothelium that is part of a pleural cavity [Automatically generated definition]." [OBOL:automatic] synonym: "meso-epithelium of pleural cavity" EXACT [OBOL:automatic] synonym: "mesothelium of pleura" EXACT [FMA:18148] synonym: "pleura" RELATED [EMAPA:16775] synonym: "pleural cavity meso-epithelium" EXACT [OBOL:automatic] synonym: "pleural cavity mesothelium" EXACT [OBOL:automatic] synonym: "pleural mesothelium" EXACT [EMAPA:16775] xref: BTO:0003155 xref: EHDAA2:0001476 xref: EMAPA:16775 xref: FMA:18148 is_a: UBERON:0001136 ! mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: located_in UBERON:0002402 ! pleural cavity relationship: located_in UBERON:0002402 ! pleural cavity [Term] id: UBERON:0003393 name: mesentery of urinary system namespace: uberon def: "A mesentery that is part of a urinary system [Automatically generated definition]." [OBOL:automatic] synonym: "excretory system mesentery" EXACT [OBOL:automatic] synonym: "mesentery of excretory system" EXACT [OBOL:automatic] synonym: "mesentery of renal system" EXACT [OBOL:automatic] synonym: "mesentery of systema urinaria" EXACT [OBOL:automatic] synonym: "renal system mesentery" EXACT [OBOL:automatic] synonym: "systema urinaria mesentery" EXACT [OBOL:automatic] synonym: "urinary system mesentery" EXACT [OBOL:automatic] xref: EMAPA:17367 xref: MA:0003233 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001008 ! renal system relationship: part_of UBERON:0001008 ! renal system [Term] id: UBERON:0003394 name: mesentery of hindgut namespace: uberon def: "A mesentery that is part of a hindgut [Automatically generated definition]." [OBOL:automatic] synonym: "hindgut mesentery" EXACT [OBOL:automatic] xref: EMAPA:16718 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001046 ! hindgut relationship: part_of UBERON:0001046 ! hindgut [Term] id: UBERON:0003395 name: mesentery of rectum namespace: uberon def: "A mesentery that is part of a rectum [Automatically generated definition]." [OBOL:automatic] synonym: "rectum mesentery" EXACT [OBOL:automatic] xref: EMAPA:18664 is_a: UBERON:0003334 ! serosa of rectum is_a: UBERON:0004854 ! gastrointestinal system mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0003396 name: mesentery of colon namespace: uberon def: "A mesentery that is part of a colon [Automatically generated definition]." [OBOL:automatic] synonym: "colon mesentery" EXACT [OBOL:automatic] synonym: "large bowel mesentery" EXACT [OBOL:automatic] synonym: "large intestinal mesentery" EXACT [FMA:14645] synonym: "mesentery of large bowel" EXACT [OBOL:automatic] synonym: "mesentery of large intestine" EXACT [FMA:14645] synonym: "mesocolon" EXACT [https://github.com/obophenotype/uberon/issues/1473] xref: EMAPA:18942 xref: FMA:14645 xref: SCTID:245457004 is_a: UBERON:0003335 ! serosa of colon is_a: UBERON:0004854 ! gastrointestinal system mesentery is_a: UBERON:0007826 {source="FMA"} ! peritoneal mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0001155 ! colon [Term] id: UBERON:0003397 name: mesentery of duodenum namespace: uberon def: "A mesentery that is part of a duodenum [Automatically generated definition]." [OBOL:automatic] synonym: "duodenum mesentery" EXACT [OBOL:automatic] xref: EMAPA:19081 is_a: UBERON:0001170 ! mesentery of small intestine is_a: UBERON:0003336 ! serosa of duodenum intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0002114 ! duodenum [Term] id: UBERON:0003403 name: skin of forearm namespace: uberon def: "A zone of skin that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "forearm skin" EXACT [FMA:38265] synonym: "lower arm skin" EXACT [OBOL:automatic] synonym: "lower segment of arm skin" EXACT [OBOL:automatic] synonym: "skin of antebrachial region" EXACT [OBOL:automatic] synonym: "skin of lower arm" EXACT [OBOL:automatic] synonym: "skin of lower segment of arm" EXACT [OBOL:automatic] synonym: "skin of zeugopod of arm" EXACT [OBOL:automatic] xref: EMAPA:18056 xref: FMA:38265 xref: MA:0000602 xref: SCTID:181537008 is_a: UBERON:0002427 ! arm skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0002386 ! forelimb zeugopod [Term] id: UBERON:0003406 name: cartilage of respiratory system namespace: uberon def: "A cartilage element that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius cartilage" EXACT [OBOL:automatic] synonym: "cartilage of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "respiratory system cartilage" EXACT [OBOL:automatic] xref: EMAPA:18694 xref: MA:0001818 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003408 name: gland of digestive tract namespace: uberon def: "A gland that is part of a digestive tract [Automatically generated definition]." [OBOL:automatic] synonym: "digestive tract gland" EXACT [OBOL:automatic] synonym: "gland of digestive tract" EXACT [OBOL:automatic] synonym: "gland of lower gastrointestinal tract" EXACT [OBOL:automatic] synonym: "gut gland" EXACT [MA:0003202] synonym: "lower gastrointestinal tract gland" EXACT [OBOL:automatic] xref: EMAPA:18815 xref: MA:0003202 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002530 ! gland is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0003409 name: gland of tongue namespace: uberon def: "Any of the mucous, serous, or mixed glands that empty their secretions onto the surface of the tongue." [http://www.merriam-webster.com/medical/lingual%20gland] synonym: "lingual gland" EXACT [OBOL:automatic] synonym: "tongue gland" EXACT [OBOL:automatic] xref: EMAPA:25097 is_a: UBERON:0010047 ! oral gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0003412 name: pelvic appendage bud mesenchyme namespace: uberon def: "Mesenchyme that is part of a pelvic appendage bud." [OBOL:automatic] synonym: "hindlimb bud mesenchyme" NARROW SENSU [EMAPA:16781] synonym: "leg mesenchyme" EXACT [OBOL:automatic] synonym: "lower limb bud mesenchyme" EXACT [EHDAA2:0001035] synonym: "mesoderm pelvic fin bud" NARROW SENSU [ZFA:0001386] synonym: "pelvic fin bud mesenchyme" NARROW SENSU [] xref: EHDAA2:0001035 xref: EMAPA:16781 xref: TAO:0001386 xref: ZFA:0001386 is_a: UBERON:0010329 ! paired limb/fin bud mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005420 ! pelvic appendage bud relationship: develops_from UBERON:0005730 ! pelvic appendage field relationship: part_of UBERON:0005420 ! pelvic appendage bud property_value: UBPROP:0000001 "Mesoderm part of pelvic fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001386", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0003413 name: pectoral appendage bud mesenchyme namespace: uberon alt_id: UBERON:0005703 def: "Mesenchyme that is part of a pectoral appendage bud." [OBOL:automatic] synonym: "arm mesenchyme" NARROW [OBOL:automatic] synonym: "forelimb bud mesenchyme" NARROW SENSU [EMAPA:16408] synonym: "mesoderm pectoral fin bud" NARROW SENSU [ZFA:0000789] synonym: "pectoral fin bud mesenchyme" NARROW SENSU [] synonym: "upper limb bud mesenchyme" NARROW [EHDAA2:0002135] synonym: "wing mesenchyme" NARROW [OBOL:automatic] xref: EHDAA2:0002135 xref: EHDAA:1703 xref: EMAPA:16408 xref: TAO:0000789 xref: ZFA:0000789 is_a: UBERON:0010329 ! paired limb/fin bud mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005419 ! pectoral appendage bud relationship: develops_from UBERON:0005729 ! pectoral appendage field relationship: part_of UBERON:0005419 ! pectoral appendage bud property_value: UBPROP:0000001 "Mesoderm that is part of the pectoral fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000789", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0003416 name: mesenchyme of tongue namespace: uberon def: "Mesenchyme that is part of a developing tongue [Automatically generated definition]." [OBOL:automatic] synonym: "tongue mesenchyme" EXACT [EHDAA2:0004614] xref: EHDAA2:0004614 xref: EMAPA:17882 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005253 ! head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0001723 ! tongue property_value: editor_note "TODO - develops_from" xsd:string [Term] id: UBERON:0003422 name: mesenchyme of umbilical cord namespace: uberon def: "A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP]." [Wikipedia:Wharton's_jelly] subset: human_reference_atlas synonym: "umbilical cord mesenchyme" EXACT [OBOL:automatic] synonym: "Wharton's jelly" EXACT [EMAPA:26127] xref: EMAPA:26127 xref: EMAPA:35925 xref: SCTID:368069009 xref: Wikipedia:Wharton's_jelly is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: has_part CHEBI:37395 {source="Wikipedia"} ! mucopolysaccharide relationship: part_of UBERON:0002331 ! umbilical cord property_value: editor_note "TODO - check" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003424 name: mesenchyme of hard palate namespace: uberon def: "Mesenchyme that is part of a developing hard palate [Automatically generated definition]." [OBOL:automatic] synonym: "hard palate mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:18954 is_a: UBERON:0003323 ! mesenchyme of upper jaw is_a: UBERON:0014387 ! mesenchyme derived from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003216 ! hard palate relationship: part_of UBERON:0003216 ! hard palate [Term] id: UBERON:0003426 name: dermis adipose tissue namespace: uberon def: "An adipose tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "adipose tissue of dermis" EXACT [OBOL:automatic] synonym: "dermis fat tissue" EXACT [OBOL:automatic] synonym: "dermis fatty tissue" EXACT [OBOL:automatic] synonym: "fat tissue of dermis" EXACT [OBOL:automatic] synonym: "fatty tissue of dermis" EXACT [OBOL:automatic] xref: MA:0000798 is_a: UBERON:0001013 ! adipose tissue is_a: UBERON:0003585 ! dermis connective tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0002067 ! dermis [Term] id: UBERON:0003429 name: abdomen nerve namespace: uberon def: "A nerve that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of abdomen" EXACT [OBOL:automatic] xref: MA:0000521 is_a: UBERON:0003825 ! nerve of abdominal segment intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0003430 name: neck nerve namespace: uberon def: "A nerve that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "neck (volume) nerve" EXACT [OBOL:automatic] synonym: "nerve of neck" EXACT [OBOL:automatic] synonym: "nerve of neck (volume)" EXACT [OBOL:automatic] xref: EMAPA:37263 {source="MA:th"} xref: MA:0000588 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003431 name: leg nerve namespace: uberon def: "A nerve that is part of a leg [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of leg" EXACT [OBOL:automatic] xref: EMAPA:37343 {source="MA:th"} xref: MA:0000673 is_a: UBERON:0003442 ! hindlimb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0000978 ! leg [Term] id: UBERON:0003433 name: arm nerve namespace: uberon def: "A nerve that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "brachial region nerve" EXACT [OBOL:automatic] synonym: "nerve of arm" EXACT [OBOL:automatic] synonym: "nerve of brachial region" EXACT [OBOL:automatic] xref: EMAPA:37336 {source="MA:th"} xref: MA:0000595 is_a: UBERON:0003441 ! forelimb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm [Term] id: UBERON:0003434 name: wrist nerve namespace: uberon def: "A nerve that is part of a wrist [Automatically generated definition]." [OBOL:automatic] synonym: "carpal region nerve" EXACT [OBOL:automatic] synonym: "nerve of carpal region" EXACT [OBOL:automatic] synonym: "nerve of wrist" EXACT [OBOL:automatic] xref: EMAPA:37339 {source="MA:th"} xref: MA:0000637 is_a: UBERON:0003448 ! manus nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0004452 ! carpal region relationship: part_of UBERON:0004452 ! carpal region [Term] id: UBERON:0003435 name: pedal digit nerve namespace: uberon def: "A nerve that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "digit of foot nerve" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb nerve" EXACT [OBOL:automatic] synonym: "digitus pedis nerve" EXACT [OBOL:automatic] synonym: "foot digit nerve" EXACT [MA:0000649] synonym: "foot digit nerve" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit nerve" EXACT [OBOL:accepted] synonym: "nerve of digit of foot" EXACT [OBOL:automatic] synonym: "nerve of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "nerve of digitus pedis" EXACT [OBOL:automatic] synonym: "nerve of foot digit" EXACT [OBOL:automatic] synonym: "nerve of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "nerve of toe" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit nerve" EXACT [OBOL:automatic] synonym: "toe nerve" EXACT [OBOL:automatic] xref: EMAPA:37348 {source="MA:th"} xref: MA:0000649 xref: SCTID:300056004 is_a: UBERON:0003445 ! pes nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0003436 name: shoulder nerve namespace: uberon def: "A nerve that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of shoulder" EXACT [OBOL:automatic] xref: EMAPA:37335 {source="MA:th"} xref: MA:0000634 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001467 ! shoulder relationship: part_of UBERON:0001467 ! shoulder [Term] id: UBERON:0003438 name: iris nerve namespace: uberon def: "Any nerve that innervates the iris." [UBERON:cjm] synonym: "ciliary nerve" NARROW [] synonym: "nerve of iris" EXACT [OBOL:automatic] xref: EMAPA:35449 xref: MA:0001291 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0001769 ! iris relationship: innervates UBERON:0001769 ! iris property_value: editor_note "added for consistency with mouse ontologies. The term 'ciliary nerve' is usually used to denote either of the two nerves (with different origins) that innervate the iris, as well as ciliary muscles and cornea" xsd:string [Term] id: UBERON:0003439 name: nerve of trunk region namespace: uberon def: "A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk)." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: non_informative synonym: "nerve of torso" EXACT [OBOL:automatic] synonym: "nerve of trunk" EXACT [OBOL:automatic] synonym: "torso nerve" EXACT [OBOL:automatic] synonym: "trunk nerve" RELATED [MA:0000515] xref: EMAPA:37264 {source="MA:th"} xref: MA:0000515 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0003440 name: limb nerve namespace: uberon def: "A nerve that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of limb" EXACT [OBOL:automatic] xref: EMAPA:37291 {source="MA:th"} xref: MA:0000693 xref: SCTID:359923002 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002101 ! limb [Term] id: UBERON:0003441 name: forelimb nerve namespace: uberon def: "A nerve that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "fore limb nerve" EXACT [OBOL:automatic] synonym: "nerve of fore limb" EXACT [OBOL:automatic] synonym: "nerve of forelimb" EXACT [OBOL:automatic] synonym: "nerve of superior member" EXACT [OBOL:automatic] synonym: "nerve of upper extremity" EXACT [OBOL:automatic] synonym: "wing nerve" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:37334 {source="MA:th"} xref: MA:0000616 is_a: UBERON:0003440 ! limb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003442 name: hindlimb nerve namespace: uberon def: "A nerve that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb nerve" EXACT [OBOL:automatic] synonym: "nerve of hind limb" EXACT [OBOL:automatic] synonym: "nerve of hindlimb" EXACT [OBOL:automatic] synonym: "nerve of inferior member" EXACT [OBOL:automatic] synonym: "nerve of lower extremity" EXACT [OBOL:automatic] xref: EMAPA:37342 {source="MA:th"} xref: MA:0000664 is_a: UBERON:0003440 ! limb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003443 name: thoracic cavity nerve namespace: uberon def: "A nerve that is located in a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest nerve" EXACT [OBOL:automatic] synonym: "cavity of thorax nerve" EXACT [OBOL:automatic] synonym: "chest cavity nerve" EXACT [OBOL:automatic] synonym: "nerve of cavity of chest" EXACT [OBOL:automatic] synonym: "nerve of cavity of thorax" EXACT [OBOL:automatic] synonym: "nerve of chest cavity" EXACT [OBOL:automatic] synonym: "nerve of pectoral cavity" EXACT [OBOL:automatic] synonym: "nerve of thoracic cavity" EXACT [OBOL:automatic] synonym: "pectoral cavity nerve" EXACT [OBOL:automatic] xref: EMAPA:37267 {source="MA:th"} xref: MA:0000556 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: located_in UBERON:0002224 ! thoracic cavity relationship: located_in UBERON:0002224 ! thoracic cavity property_value: editor_note "consider merging with thoracic nerve. In MA the only subclass is the phrenic nerve, which arises from a cervical nerve" xsd:string [Term] id: UBERON:0003444 name: pelvis nerve namespace: uberon def: "A nerve that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37269 {source="MA:th"} xref: MA:0000542 is_a: UBERON:0003825 ! nerve of abdominal segment intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002355 ! pelvic region of trunk [Term] id: UBERON:0003445 name: pes nerve namespace: uberon def: "A nerve that is part of a foot [Automatically generated definition]." [OBOL:automatic] synonym: "foot nerve" EXACT [MA:0000653] synonym: "nerve of foot" EXACT [OBOL:automatic] xref: EMAPA:37347 {source="MA:th"} xref: MA:0000653 is_a: UBERON:0003442 ! hindlimb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0002387 ! pes [Term] id: UBERON:0003446 name: ankle nerve namespace: uberon def: "A nerve that is part of an ankle [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of ankle" EXACT [OBOL:automatic] synonym: "neural network of ankle" RELATED [FMA:86901] synonym: "tarsal region nerve" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37346 {source="MA:th"} xref: MA:0000640 is_a: UBERON:0003445 ! pes nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0004454 ! tarsal region relationship: part_of UBERON:0004454 ! tarsal region property_value: seeAlso FMA:86901 property_value: UBPROP:0000012 "FMA placement dubious" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003447 name: digit nerve of manus namespace: uberon def: "A nerve that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "digit of hand nerve" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb nerve" EXACT [OBOL:automatic] synonym: "digitus manus nerve" EXACT [OBOL:automatic] synonym: "finger nerve" EXACT [OBOL:automatic] synonym: "hand digit nerve" EXACT [MA:0000625] synonym: "nerve of digit of hand" EXACT [OBOL:automatic] synonym: "nerve of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "nerve of digitus manus" EXACT [OBOL:automatic] synonym: "nerve of finger" EXACT [OBOL:automatic] synonym: "nerve of hand digit" EXACT [OBOL:automatic] synonym: "nerve of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit nerve" EXACT [OBOL:automatic] xref: EMAPA:37341 {source="MA:th"} xref: MA:0000625 xref: SCTID:181015006 is_a: UBERON:0003448 ! manus nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0002389 ! manual digit [Term] id: UBERON:0003448 name: manus nerve namespace: uberon def: "A nerve that is part of a manus [Automatically generated definition]." [OBOL:automatic] synonym: "hand nerve" EXACT [MA:0000629] synonym: "nerve of hand" EXACT [UBERON:cjm] synonym: "nerve of manus" EXACT [OBOL:automatic] xref: EMAPA:37340 {source="MA:th"} xref: MA:0000629 is_a: UBERON:0003441 ! forelimb nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0002398 ! manus [Term] id: UBERON:0003450 name: upper jaw incisor namespace: uberon def: "An incisor tooth that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "incisor of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "incisor of upper jaw" EXACT [OBOL:automatic] synonym: "incisor tooth of palatoquadrate arch" EXACT [OBOL:automatic] synonym: "incisor tooth of upper jaw" EXACT [OBOL:automatic] synonym: "maxillary incisor tooth" RELATED [FMA:55712] synonym: "palatoquadrate arch incisor" EXACT [OBOL:automatic] synonym: "palatoquadrate arch incisor tooth" EXACT [OBOL:automatic] synonym: "premaxillary tooth" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "upper incisor" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "upper jaw incisor tooth" EXACT [OBOL:automatic] xref: EHDAA2:0002121 xref: EMAPA:17939 xref: FMA:321754 xref: MA:0001601 xref: NCIT:C49794 xref: SCTID:421578001 xref: UMLS:C1710579 {source="ncithesaurus:Upper_Jaw_Incisor"} is_a: UBERON:0001098 ! incisor tooth is_a: UBERON:2001626 ! premaxillary tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0003451 name: lower jaw incisor namespace: uberon def: "An incisor tooth that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "incisor of lower jaw" EXACT [OBOL:automatic] synonym: "incisor of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "incisor tooth of lower jaw" EXACT [OBOL:automatic] synonym: "incisor tooth of ventral mandibular arch" EXACT [OBOL:automatic] synonym: "lower incisor" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "lower jaw incisor tooth" EXACT [OBOL:automatic] synonym: "mandibular incisor" EXACT [BTO:0001942] synonym: "ventral mandibular arch incisor" EXACT [OBOL:automatic] synonym: "ventral mandibular arch incisor tooth" EXACT [OBOL:automatic] xref: BTO:0001942 xref: EHDAA2:0001021 xref: EMAPA:17918 xref: MA:0001600 xref: NCIT:C49583 xref: UMLS:C1708755 {source="ncithesaurus:Lower_Jaw_Incisor"} is_a: UBERON:0001098 ! incisor tooth is_a: UBERON:0003268 ! tooth of lower jaw intersection_of: UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0003452 name: trabecula carnea cardiac muscle tissue namespace: uberon def: "A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "cardiac muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "cardiac muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart muscle muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart muscle textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "heart myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle of heart muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle of heart textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of heart muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of heart myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of muscle of heart of trabecula carnea" EXACT [OBOL:automatic] synonym: "muscle tissue of myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "myocardium muscle tissue of trabecula carnea" EXACT [OBOL:automatic] synonym: "myocardium textus muscularis of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of cardiac muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of heart muscle of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of heart myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of muscle of heart of trabecula carnea" EXACT [OBOL:automatic] synonym: "textus muscularis of myocardium of trabecula carnea" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea cardiac muscle textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea heart muscle muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea heart muscle textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea heart myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea heart myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle of heart muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle of heart textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of heart muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of heart myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of muscle of heart" EXACT [OBOL:automatic] synonym: "trabecula carnea muscle tissue of myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea myocardium muscle tissue" EXACT [OBOL:automatic] synonym: "trabecula carnea myocardium textus muscularis" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of cardiac muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of heart muscle" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of heart myocardium" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of muscle of heart" EXACT [OBOL:automatic] synonym: "trabecula carnea textus muscularis of myocardium" EXACT [OBOL:automatic] xref: EMAPA:36573 xref: FMA:84428 xref: MA:0002833 is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002511 ! trabecula carnea relationship: part_of UBERON:0002511 ! trabecula carnea [Term] id: UBERON:0003457 name: head bone namespace: uberon def: "A bone that is part of a head [Automatically generated definition]." [OBOL:automatic] comment: Different sources vary regarding which bones are craniofacial; e.g. hyoid bone subset: pheno_slim synonym: "adult head bone" EXACT [OBOL:automatic] synonym: "adult head bone organ" EXACT [OBOL:automatic] synonym: "bone of adult head" EXACT [OBOL:automatic] synonym: "bone of head" EXACT [OBOL:automatic] synonym: "bone organ of adult head" EXACT [OBOL:automatic] synonym: "bone organ of head" EXACT [OBOL:automatic] synonym: "craniofacial bone" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "head bone organ" EXACT [OBOL:automatic] xref: EMAPA:35996 xref: MA:0000576 xref: SCTID:118646007 is_a: UBERON:0007914 ! bone of craniocervical region intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0003458 name: neck bone namespace: uberon def: "A bone that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "bone of neck" EXACT [OBOL:automatic] synonym: "bone of neck (volume)" EXACT [OBOL:automatic] synonym: "bone organ of neck" EXACT [OBOL:automatic] synonym: "bone organ of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) bone" EXACT [OBOL:automatic] synonym: "neck (volume) bone organ" EXACT [OBOL:automatic] synonym: "neck bone organ" EXACT [OBOL:automatic] xref: EMAPA:37246 {source="MA:th"} xref: MA:0000584 is_a: UBERON:0007914 ! bone of craniocervical region intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003460 name: arm bone namespace: uberon def: "A bone that is part of the region of the forelimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "arm bone organ" EXACT [OBOL:automatic] synonym: "bone of arm" EXACT [OBOL:automatic] synonym: "bone of upper extremity" RELATED [GAID:178] synonym: "bone organ of arm" EXACT [OBOL:automatic] xref: EMAPA:37303 {source="MA:th"} xref: MA:0000592 xref: MESH:D050280 is_a: UBERON:0008962 ! forelimb bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003461 name: shoulder bone namespace: uberon def: "A bone that is connected via a shoulder joint (i.e. glenohumeral or acromioclavicular joints). The shoulder bones are the clavicle, scapula and humerus - but note that these are only considered to be shoulder bones when a true shoulder is present, as in most tetrapods." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "bone of shoulder" EXACT [OBOL:automatic] synonym: "shoulder-articulating bone" EXACT [] xref: MA:0000631 is_a: UBERON:0010741 {notes="UBERONREF:0000003", source="MA"} ! bone of pectoral complex intersection_of: UBERON:0001474 ! bone element intersection_of: overlaps UBERON:0016884 ! shoulder joint relationship: overlaps UBERON:0016884 ! shoulder joint relationship: part_of UBERON:0012475 ! skeleton of pectoral complex property_value: UBPROP:0000012 "this is a forelimb bone in MA, but this would lead to part-disjointness violations." xsd:string {external_ontology="MA"} [Term] id: UBERON:0003462 name: facial bone namespace: uberon def: "A bone that is part of a facial skeleton [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "bone of facial skeleton" EXACT [OBOL:automatic] synonym: "bone of viscerocranium" RELATED [OBOL:automatic] synonym: "facial bone" EXACT [EMAPA:19019] synonym: "facial skeleton bone" EXACT [OBOL:automatic] synonym: "viscerocranium bone" RELATED [OBOL:automatic] xref: EMAPA:19019 xref: EMAPA:35924 xref: MA:0001482 xref: MA:0003159 xref: MESH:D005147 xref: NCIT:C63706 xref: SCTID:181799005 xref: UMLS:C0015455 {source="ncithesaurus:Facial_Bone"} is_a: UBERON:0003457 ! head bone is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0011156 ! facial skeleton relationship: part_of UBERON:0011156 {source="MA"} ! facial skeleton property_value: editor_note "test whether 'facial bone' is an exact synonym" xsd:string [Term] id: UBERON:0003463 name: trunk bone namespace: uberon def: "A bone that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "bone of torso" EXACT [OBOL:automatic] synonym: "bone of trunk" EXACT [OBOL:automatic] synonym: "bone organ of torso" EXACT [OBOL:automatic] synonym: "bone organ of trunk" EXACT [OBOL:automatic] synonym: "torso bone" EXACT [OBOL:automatic] synonym: "torso bone organ" EXACT [OBOL:automatic] synonym: "trunk bone organ" EXACT [OBOL:automatic] xref: EMAPA:36583 xref: MA:0000512 xref: SCTID:427358002 is_a: UBERON:0001474 ! bone element is_a: UBERON:0005177 ! trunk region element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0003464 name: hindlimb bone namespace: uberon def: "A bone that is part of a hindlimb region. Examples: any pes phalanx, femur. Counter-examples: ischium, pubis (they are part of the pelvic girdle)." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "bone of hind limb" EXACT [OBOL:automatic] synonym: "bone of hindlimb" EXACT [OBOL:automatic] synonym: "bone of inferior member" EXACT [OBOL:automatic] synonym: "bone of lower extremity" EXACT [OBOL:automatic] synonym: "bone organ of hind limb" EXACT [OBOL:automatic] synonym: "bone organ of hindlimb" EXACT [OBOL:automatic] synonym: "bone organ of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb bone" EXACT [OBOL:automatic] synonym: "hind limb bone organ" EXACT [OBOL:automatic] synonym: "hindlimb bone organ" EXACT [OBOL:automatic] xref: EFO:0003842 xref: GAID:198 xref: NCIT:C12982 xref: SCTID:361370006 xref: UMLS:C0448188 {source="ncithesaurus:Bone_of_the_Lower_Extremity"} is_a: UBERON:0002428 ! limb bone is_a: UBERON:0010742 ! bone of pelvic complex is_a: UBERON:0015022 ! hindlimb endochondral element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002103 ! hindlimb relationship: develops_from UBERON:0010885 ! hindlimb cartilage element property_value: UBPROP:0000012 "the MA class is actually bone of pelvic complex; in contrast the NCIT class excludes ilium etc" xsd:string {external_ontology="MA"} [Term] id: UBERON:0003466 name: forelimb zeugopod bone namespace: uberon def: "A bone that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "antebrachial region bone" EXACT [OBOL:automatic] synonym: "antebrachial region bone organ" EXACT [OBOL:automatic] synonym: "arm zeugopod bone" EXACT [OBOL:automatic] synonym: "arm zeugopod bone organ" EXACT [OBOL:automatic] synonym: "lower arm bone" EXACT [MA:0000598] synonym: "wing zeugopod bone" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "zeugopod bone, forelimb" EXACT [OBOL:automatic] synonym: "zeugopod bone, upper" EXACT [OBOL:automatic] xref: EMAPA:35347 xref: MA:0000598 is_a: UBERON:0003460 ! arm bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton [Term] id: UBERON:0003468 name: ureteric segment of renal artery namespace: uberon def: "The ureteral branches of renal artery are small branches which supply the ureter." [Wikipedia:Ureteral_branches_of_renal_artery] subset: human_reference_atlas synonym: "ureteric artery" BROAD [MA:0002074] xref: EMAPA:37676 {source="MA:th"} xref: FMA:70491 xref: MA:0002074 xref: SCTID:65376008 xref: Wikipedia:Ureteral_branches_of_renal_artery is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000056 ! ureter relationship: branching_part_of UBERON:0001184 {source="FMA"} ! renal artery relationship: part_of UBERON:0001184 {source="FMA"} ! renal artery relationship: supplies UBERON:0000056 ! ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003469 name: respiratory system artery namespace: uberon def: "An artery that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37569 {source="MA:th"} xref: MA:0001804 is_a: UBERON:0001637 ! artery is_a: UBERON:0003643 ! respiratory system arterial blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003470 name: artery of upper lip namespace: uberon def: "The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose." [Wikipedia:Superior_labial_artery] subset: human_reference_atlas synonym: "arteria labialis superior" EXACT LATIN [Wikipedia:Superior_labial_artery] synonym: "ramus labialis superior arteriae facialis" EXACT LATIN [Wikipedia:Superior_labial_artery] synonym: "superior labial artery" EXACT [FMA:49570] synonym: "superior labial branch of facial artery" EXACT [FMA:49570] xref: EMAPA:37430 {source="MA:th"} xref: FMA:49570 xref: MA:0001917 xref: SCTID:145137009 xref: Wikipedia:Superior_labial_artery is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0004573 ! systemic artery is_a: UBERON:0009657 ! artery of lip intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001834 ! upper lip relationship: branching_part_of UBERON:0001612 {source="FMA"} ! facial artery relationship: part_of UBERON:0001612 ! facial artery relationship: supplies UBERON:0001834 ! upper lip property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003471 name: artery of lower lip namespace: uberon def: "The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery." [Wikipedia:Inferior_labial_artery] subset: human_reference_atlas synonym: "arteria labialis inferior" EXACT LATIN [Wikipedia:Inferior_labial_artery] synonym: "inferior labial artery" EXACT [FMA:49567] synonym: "inferior labial branch of facial artery" EXACT [FMA:49567] synonym: "ramus labialis inferior (arteria facialis)" EXACT [FMA:TA] synonym: "ramus labialis inferior arteriae facialis" EXACT LATIN [Wikipedia:Inferior_labial_artery] xref: EMAPA:37429 {source="MA:th"} xref: FMA:49567 xref: MA:0001916 xref: SCTID:145036002 xref: Wikipedia:Inferior_labial_artery is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0004573 ! systemic artery is_a: UBERON:0009657 ! artery of lip intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001835 ! lower lip relationship: branching_part_of UBERON:0001612 {source="FMA"} ! facial artery relationship: part_of UBERON:0001612 ! facial artery relationship: supplies UBERON:0001835 ! lower lip property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003473 name: thoracic cavity artery namespace: uberon def: "An artery that is part of a thoracic cavity[cjm]." [https://sourceforge.net/tracker/index.php?func=detail&aid=3317815&group_id=76834&atid=1205376] synonym: "thoracic artery" RELATED [MESH:A07.231.114.891] xref: EMAPA:37241 {source="MA:th"} xref: MA:0001902 xref: MESH:D013895 is_a: UBERON:0001637 ! artery is_a: UBERON:0003519 ! thoracic cavity blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: located_in UBERON:0002224 ! thoracic cavity property_value: UBPROP:0000012 "in MA, aorta is classified here - but this is problematic because the abdominal aorta is not in the thoracic cavity" xsd:string {external_ontology="MA"} [Term] id: UBERON:0003474 name: meningeal artery namespace: uberon def: "One of the arteries supplying a meninix[Automatically generated definition]." [Wikipedia:Meningeal_arteries] xref: EMAPA:37104 {source="MA:th"} xref: GAID:499 xref: MA:0002001 xref: MESH:D008576 xref: Wikipedia:Meningeal_arteries is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0002360 ! meninx relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0002360 ! meninx [Term] id: UBERON:0003475 name: ureteric vein namespace: uberon def: "A vein that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "ureter vein" EXACT [OBOL:automatic] synonym: "vein of ureter" EXACT [OBOL:automatic] xref: EMAPA:37679 {source="MA:th"} xref: MA:0002250 is_a: UBERON:0001638 ! vein is_a: UBERON:0003520 ! pelvis blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0003476 name: respiratory system venous blood vessel namespace: uberon def: "A vein that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius vein" EXACT [OBOL:automatic] synonym: "respiratory system vein" EXACT [OBOL:automatic] synonym: "vein of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "vein of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37584 {source="MA:th"} xref: MA:0001809 xref: MA:0001810 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001004 ! respiratory system relationship: drains UBERON:0001004 ! respiratory system relationship: part_of RO:0002577 ! system [Term] id: UBERON:0003477 name: vein of upper lip namespace: uberon def: "The inferior labial vein is the vein receiving blood from the upper lip." [Wikipedia:Superior_labial_vein] subset: human_reference_atlas synonym: "superior labial vein" EXACT [FMA:52538] synonym: "upper lip vein" EXACT [OBOL:automatic] synonym: "vena labialis superior" EXACT LATIN [] xref: EMAPA:37204 {source="MA:th"} xref: FMA:52538 xref: MA:0002255 xref: SCTID:422755007 xref: Wikipedia:Superior_labial_vein is_a: UBERON:0013136 ! vein of lip intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001834 ! upper lip relationship: drains UBERON:0001834 ! upper lip property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003478 name: vein of lower lip namespace: uberon def: "The inferior labial vein is the vein receiving blood from the lower lip." [Wikipedia:Inferior_labial_vein] subset: human_reference_atlas synonym: "inferior labial vein" EXACT [FMA:52541] synonym: "lower lip vein" EXACT [OBOL:automatic] synonym: "vena labialis inferior" EXACT LATIN [] synonym: "venae labiales inferiores" RELATED LATIN [Wikipedia:Inferior_labial_vein] xref: EMAPA:37202 {source="MA:th"} xref: FMA:52541 xref: MA:0002253 xref: SCTID:422955002 xref: Wikipedia:Inferior_labial_vein is_a: UBERON:0013136 ! vein of lip intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001835 ! lower lip relationship: drains UBERON:0001835 ! lower lip property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8c/Gray557.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003479 name: thoracic cavity vein namespace: uberon def: "A vein that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest vein" EXACT [OBOL:automatic] synonym: "cavity of thorax vein" EXACT [OBOL:automatic] synonym: "chest cavity vein" EXACT [OBOL:automatic] synonym: "pectoral cavity vein" EXACT [OBOL:automatic] synonym: "vein of cavity of chest" EXACT [OBOL:automatic] synonym: "vein of cavity of thorax" EXACT [OBOL:automatic] synonym: "vein of chest cavity" EXACT [OBOL:automatic] synonym: "vein of pectoral cavity" EXACT [OBOL:automatic] synonym: "vein of thoracic cavity" EXACT [OBOL:automatic] xref: EMAPA:37242 {source="MA:th"} xref: MA:0001903 is_a: UBERON:0001638 ! vein is_a: UBERON:0003519 ! thoracic cavity blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003480 name: vein of clitoris namespace: uberon def: "A vein that is part of a clitoris [Automatically generated definition]." [OBOL:automatic] synonym: "clitoris vein" EXACT [OBOL:automatic] xref: EMAPA:37201 {source="MA:th"} xref: MA:0002252 xref: SCTID:360819004 is_a: UBERON:0001638 ! vein is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0002411 ! clitoris relationship: part_of UBERON:0002411 ! clitoris [Term] id: UBERON:0003481 name: tail vein namespace: uberon def: "A vein that is part of a tail [Automatically generated definition]." [OBOL:automatic, Wikipedia:Tail_vein] synonym: "caudal vein" RELATED [Wikipedia:Tail_vein] synonym: "post-vent region vein" EXACT [OBOL:automatic] synonym: "vein of post-vent region" EXACT [OBOL:automatic] synonym: "vein of tail" EXACT [OBOL:automatic] xref: AAO:0011105 xref: EMAPA:37761 {source="MA:th"} xref: MA:0002233 xref: Wikipedia:Tail_vein xref: XAO:0000393 is_a: UBERON:0001638 ! vein is_a: UBERON:0003524 ! tail blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0007812 ! post-anal tail property_value: editor_note "see also caudal vein" xsd:string [Term] id: UBERON:0003489 name: respiratory system capillary endothelium namespace: uberon def: "An endothelium of capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood capillary endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of capillary vessel" EXACT [OBOL:automatic] synonym: "blood capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood capillary endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "capillary endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "capillary vessel endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary vessel endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of blood capillary of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of capillary of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of capillary vessel of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system blood capillary endothelium" EXACT [OBOL:automatic] synonym: "respiratory system capillary vessel endothelium" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of blood capillary" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of capillary" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of capillary vessel" EXACT [OBOL:automatic] xref: EMAPA:37575 {source="MA:th"} xref: MA:0001808 is_a: UBERON:0001915 ! endothelium of capillary is_a: UBERON:0004702 ! respiratory system blood vessel endothelium intersection_of: UBERON:0001915 ! endothelium of capillary intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003526 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system capillary [Term] id: UBERON:0003494 name: respiratory system venule namespace: uberon def: "A venule that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius venule" EXACT [OBOL:automatic] synonym: "venule of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "venule of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37587 {source="MA:th"} xref: MA:0001813 is_a: UBERON:0001979 ! venule is_a: UBERON:0003504 ! respiratory system blood vessel intersection_of: UBERON:0001979 ! venule intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003495 name: respiratory system arteriole namespace: uberon def: "An arteriole that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37568 {source="MA:th"} xref: MA:0001803 is_a: UBERON:0001980 ! arteriole is_a: UBERON:0003643 ! respiratory system arterial blood vessel intersection_of: UBERON:0001980 ! arteriole intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003469 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system artery [Term] id: UBERON:0003496 name: head blood vessel namespace: uberon def: "A blood vessel that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of adult head" EXACT [OBOL:automatic] synonym: "blood vessel of head" EXACT [OBOL:automatic] xref: EMAPA:36610 xref: MA:0000575 xref: SCTID:127865000 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0011362 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! cranial blood vasculature [Term] id: UBERON:0003497 name: abdomen blood vessel namespace: uberon def: "A blood vessel that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of abdomen" EXACT [OBOL:automatic] xref: MA:0000518 is_a: UBERON:0003835 ! abdominal segment blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen property_value: seeAlso "UBERON:0012254" xsd:string {notes="abdominal aorta artery"} [Term] id: UBERON:0003498 name: heart blood vessel namespace: uberon def: "A blood vessel that is part of a heart [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "blood vessel of heart" EXACT [OBOL:automatic] synonym: "cardiac blood vessel" RELATED [EMAPA:35397] xref: EMAPA:35397 xref: MA:0002483 is_a: UBERON:0003834 ! thoracic segment blood vessel is_a: UBERON:0005985 ! coronary vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0018674 ! heart vasculature [Term] id: UBERON:0003499 name: brain blood vessel namespace: uberon def: "A blood vessel that is part of a brain [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "blood vessel of brain" EXACT [OBOL:automatic] xref: EMAPA:35182 xref: MA:0002769 is_a: UBERON:0001981 ! blood vessel is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0008998 ! vasculature of brain [Term] id: UBERON:0003500 name: corneal blood vessel namespace: uberon def: "A blood vessel that is part of a cornea [Automatically generated definition]." [https://orcid.org/0000-0002-6601-2165, https://sourceforge.net/tracker/index.php?func=detail&aid=3564332&group_id=36855&atid=440764] synonym: "blood vessel of cornea" EXACT [OBOL:automatic] synonym: "cornea blood vessel" EXACT [OBOL:automatic] xref: EMAPA:36611 xref: MA:0001241 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000964 ! cornea relationship: part_of UBERON:0000964 ! cornea property_value: editor_note "follow up on tracker item" xsd:string property_value: RO:0002175 NCBITaxon:9775 {source="PMID:17051153"} [Term] id: UBERON:0003501 name: retina blood vessel namespace: uberon def: "A blood vessel that is part of a retina [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "blood vessel of inner layer of eyeball" EXACT [OBOL:automatic] synonym: "blood vessel of retina" EXACT [OBOL:automatic] synonym: "blood vessel of tunica interna of eyeball" EXACT [OBOL:automatic] synonym: "inner layer of eyeball blood vessel" EXACT [OBOL:automatic] synonym: "retinal blood vessel" EXACT [OBOL:automatic] synonym: "tunica interna of eyeball blood vessel" EXACT [OBOL:automatic] xref: EMAPA:36520 xref: GAID:509 xref: MA:0001317 xref: MESH:D012171 xref: SCTID:280692003 xref: XAO:0004153 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000966 ! retina relationship: contributes_to_morphology_of UBERON:0000966 ! retina relationship: part_of UBERON:0004864 ! vasculature of retina [Term] id: UBERON:0003502 name: neck blood vessel namespace: uberon def: "A blood vessel that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of neck" EXACT [OBOL:automatic] synonym: "blood vessel of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37236 {source="MA:th"} xref: MA:0000583 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003503 name: leg blood vessel namespace: uberon def: "A blood vessel that is part of a leg [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of leg" EXACT [OBOL:automatic] xref: EMAPA:36500 xref: MA:0000669 is_a: UBERON:0003516 ! hindlimb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0000978 ! leg [Term] id: UBERON:0003504 name: respiratory system blood vessel namespace: uberon def: "A blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood vessel of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:35731 xref: EMAPA:35995 xref: MA:0001799 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003505 name: trachea blood vessel namespace: uberon alt_id: UBERON:0003525 def: "A blood vessel that is part of a trachea." [OBOL:automatic] subset: human_reference_atlas synonym: "blood vessel of trachea" EXACT [OBOL:automatic] xref: EMAPA:35874 xref: MA:0001852 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003504 ! respiratory system blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0003126 ! trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003507 name: arm blood vessel namespace: uberon def: "A blood vessel that is part of an arm [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of arm" EXACT [OBOL:automatic] xref: EMAPA:37293 {source="MA:th"} xref: MA:0000591 is_a: UBERON:0003515 ! forelimb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm [Term] id: UBERON:0003508 name: pedal digit blood vessel namespace: uberon def: "A blood vessel that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of digit of foot" EXACT [OBOL:automatic] synonym: "blood vessel of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "blood vessel of digitus pedis" EXACT [OBOL:automatic] synonym: "blood vessel of foot digit" EXACT [OBOL:automatic] synonym: "blood vessel of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "blood vessel of toe" EXACT [OBOL:automatic] synonym: "digit of foot blood vessel" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb blood vessel" EXACT [OBOL:automatic] synonym: "digitus pedis blood vessel" EXACT [OBOL:automatic] synonym: "foot digit blood vessel" EXACT [MA:0000645] synonym: "foot digit blood vessel" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit blood vessel" EXACT [OBOL:accepted] synonym: "terminal segment of free lower limb digit blood vessel" EXACT [OBOL:automatic] synonym: "toe blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37302 {source="MA:th"} xref: MA:0000645 is_a: UBERON:0003521 ! pes blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0003509 name: arterial blood vessel namespace: uberon def: "A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta." [https://orcid.org/0000-0002-6601-2165] comment: only in MA - supertype of artery, arteriole, aorta. subset: pheno_slim xref: EMAPA:35144 xref: MA:0000061 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004572 ! arterial system relationship: part_of UBERON:0004572 ! arterial system [Term] id: UBERON:0003511 name: iris blood vessel namespace: uberon def: "A blood vessel that is part of a iris [Automatically generated definition]." [OBOL:automatic] subset: vertebrate_core synonym: "blood vessel of iris" EXACT [OBOL:automatic] xref: EMAPA:37387 {source="MA:th"} xref: MA:0001290 xref: ZFA:0005568 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001769 ! iris relationship: part_of UBERON:0004118 ! vasculature of iris [Term] id: UBERON:0003512 name: lung blood vessel namespace: uberon def: "A blood vessel that is part of a lung [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "blood vessel of lung" EXACT [OBOL:automatic] synonym: "pulmonary vascular element" RELATED [EMAPA:32867] xref: EMAPA:32867 xref: MA:0002457 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003504 ! respiratory system blood vessel is_a: UBERON:0003834 ! thoracic segment blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002048 ! lung relationship: contributes_to_morphology_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0003513 name: trunk blood vessel namespace: uberon def: "A blood vessel that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of torso" EXACT [OBOL:automatic] synonym: "blood vessel of trunk" EXACT [OBOL:automatic] synonym: "torso blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37237 {source="MA:th"} xref: MA:0000511 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0003514 name: limb blood vessel namespace: uberon def: "A blood vessel that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of limb" EXACT [OBOL:automatic] xref: EMAPA:36598 xref: MA:0000687 is_a: UBERON:0007301 ! appendage blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002101 ! limb [Term] id: UBERON:0003515 name: forelimb blood vessel namespace: uberon def: "A blood vessel that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "anteriormost limb blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of anteriormost limb" EXACT [OBOL:automatic] synonym: "blood vessel of fore limb" EXACT [OBOL:automatic] synonym: "blood vessel of forelimb" EXACT [OBOL:automatic] synonym: "blood vessel of upper extremity" EXACT [OBOL:automatic] synonym: "fore limb blood vessel" EXACT [OBOL:automatic] synonym: "wing blood vessel" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:37292 {source="MA:th"} xref: MA:0000611 is_a: UBERON:0003514 ! limb blood vessel is_a: UBERON:0007300 ! pectoral appendage blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003516 name: hindlimb blood vessel namespace: uberon def: "A blood vessel that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of hind limb" EXACT [OBOL:automatic] synonym: "blood vessel of hindlimb" EXACT [OBOL:automatic] synonym: "blood vessel of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37298 {source="MA:th"} xref: MA:0000659 is_a: UBERON:0003514 ! limb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003517 name: kidney blood vessel namespace: uberon def: "A blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "blood vessel of kidney" EXACT [OBOL:automatic] synonym: "renal blood vessel" EXACT [OBOL:automatic] xref: EMAPA:28457 xref: MA:0001682 xref: TAO:0005306 xref: ZFA:0005306 is_a: UBERON:0003497 ! abdomen blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0006544 ! kidney vasculature property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003519 name: thoracic cavity blood vessel namespace: uberon def: "A blood vessel that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of cavity of chest" EXACT [OBOL:automatic] synonym: "blood vessel of cavity of thorax" EXACT [OBOL:automatic] synonym: "blood vessel of chest cavity" EXACT [OBOL:automatic] synonym: "blood vessel of pectoral cavity" EXACT [OBOL:automatic] synonym: "blood vessel of thoracic cavity" EXACT [OBOL:automatic] synonym: "cavity of chest blood vessel" EXACT [OBOL:automatic] synonym: "cavity of thorax blood vessel" EXACT [OBOL:automatic] synonym: "chest cavity blood vessel" EXACT [OBOL:automatic] synonym: "pectoral cavity blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37240 {source="MA:th"} xref: MA:0000554 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: located_in UBERON:0002224 ! thoracic cavity relationship: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003520 name: pelvis blood vessel namespace: uberon def: "A blood vessel that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37244 {source="MA:th"} xref: MA:0000531 is_a: UBERON:0003835 ! abdominal segment blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002355 ! pelvic region of trunk [Term] id: UBERON:0003521 name: pes blood vessel namespace: uberon def: "A blood vessel that is part of a foot [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of foot" EXACT [OBOL:automatic] synonym: "foot blood vessel" EXACT [MA:0000642] xref: EMAPA:37301 {source="MA:th"} xref: MA:0000642 is_a: UBERON:0003516 ! hindlimb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0002387 ! pes [Term] id: UBERON:0003522 name: manual digit blood vessel namespace: uberon def: "A blood vessel that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "blood vessel of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb blood vessel" EXACT [OBOL:automatic] synonym: "finger blood vessel" EXACT [OBOL:automatic] synonym: "hand digit blood vessel" EXACT [MA:0000621] synonym: "hand digit blood vessel" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "terminal segment of free upper limb digit blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37297 {source="MA:th"} xref: MA:0000621 is_a: UBERON:0003523 ! manus blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0002389 ! manual digit [Term] id: UBERON:0003523 name: manus blood vessel namespace: uberon def: "A blood vessel that is part of a manus [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of hand" EXACT [OBOL:automatic] synonym: "blood vessel of manus" EXACT [OBOL:automatic] synonym: "hand blood vessel" EXACT [MA:0000618] xref: EMAPA:37296 {source="MA:th"} xref: MA:0000618 is_a: UBERON:0003515 ! forelimb blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0002398 ! manus [Term] id: UBERON:0003524 name: tail blood vessel namespace: uberon def: "A blood vessel that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of post-vent region" EXACT [OBOL:automatic] synonym: "blood vessel of tail" EXACT [OBOL:automatic] synonym: "post-vent region blood vessel" EXACT [OBOL:automatic] xref: EMAPA:35848 xref: MA:0000695 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0003526 name: respiratory system capillary namespace: uberon def: "A capillary that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius blood capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary" EXACT [OBOL:automatic] synonym: "apparatus respiratorius capillary vessel" EXACT [OBOL:automatic] synonym: "blood capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "blood capillary of respiratory system" EXACT [OBOL:automatic] synonym: "capillary of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary of respiratory system" EXACT [OBOL:automatic] synonym: "capillary vessel of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "capillary vessel of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system blood capillary" EXACT [OBOL:automatic] synonym: "respiratory system capillary vessel" EXACT [OBOL:automatic] xref: EMAPA:37574 {source="MA:th"} xref: MA:0001807 is_a: UBERON:0001982 ! capillary is_a: UBERON:0003504 ! respiratory system blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003527 name: kidney capillary namespace: uberon def: "A capillary that is part of a kidney [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "blood capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary of kidney" EXACT [OBOL:automatic] synonym: "capillary vessel of kidney" EXACT [OBOL:automatic] synonym: "kidney blood capillary" EXACT [OBOL:automatic] synonym: "kidney capillary vessel" EXACT [OBOL:automatic] synonym: "renal capillary" EXACT [OBOL:automatic] xref: EMAPA:31443 xref: MA:0002586 xref: SCTID:275409003 is_a: UBERON:0001982 ! capillary is_a: UBERON:0003517 ! kidney blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0002113 ! kidney property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003528 name: brain gray matter namespace: uberon def: "A gray matter that is part of a brain [Automatically generated definition]." [OBOL:automatic] synonym: "brain grey matter" EXACT [MA:0000810] synonym: "brain grey substance" EXACT [OBOL:automatic] synonym: "gray matter of brain" EXACT [OBOL:automatic] synonym: "grey matter of brain" EXACT [OBOL:automatic] synonym: "grey substance of brain" EXACT [OBOL:automatic] xref: EMAPA:35184 xref: MA:0000810 xref: NCIT:C49333 xref: UMLS:C1707348 {source="ncithesaurus:Cerebral_Gray_Matter"} is_a: UBERON:0002020 ! gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0000955 ! brain [Term] id: UBERON:0003530 name: pedal digit skin namespace: uberon def: "A zone of skin that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "digit of foot skin" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb skin" EXACT [OBOL:automatic] synonym: "digitus pedis skin" EXACT [OBOL:automatic] synonym: "foot digit skin" EXACT [MA:0000650] synonym: "foot digit skin" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit skin" EXACT [OBOL:accepted] synonym: "skin of digit of foot" EXACT [OBOL:automatic] synonym: "skin of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "skin of digitus pedis" EXACT [OBOL:automatic] synonym: "skin of foot digit" EXACT [OBOL:automatic] synonym: "skin of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "skin of toe" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit skin" EXACT [OBOL:automatic] synonym: "toe skin" EXACT [OBOL:automatic] xref: EMAPA:32942 xref: FMA:37852 xref: MA:0000650 xref: NCIT:C52719 xref: SCTID:181530005 xref: UMLS:C1708089 {source="ncithesaurus:Foot_Digit_Skin"} is_a: UBERON:0001513 ! skin of pes is_a: UBERON:0015249 ! digit skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0003531 name: forelimb skin namespace: uberon def: "A zone of skin that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "anteriormost limb skin" EXACT [OBOL:automatic] synonym: "fore limb skin" EXACT [OBOL:automatic] synonym: "skin of fore limb" EXACT [OBOL:automatic] synonym: "skin of forelimb" EXACT [OBOL:automatic] synonym: "skin of upper limb" EXACT [FMA:23101] synonym: "upper limb skin" EXACT [FMA:23101] synonym: "wing skin" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:32612 xref: FMA:23101 xref: MA:0000617 xref: NCIT:C12296 xref: SCTID:244130001 xref: UMLS:C0222212 {source="ncithesaurus:Skin_of_the_Upper_Limb_and_Shoulder"} is_a: UBERON:0001419 ! skin of limb intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 ! forelimb property_value: editor_note "TODO - check free limb vs pectoral complex" xsd:string [Term] id: UBERON:0003532 name: hindlimb skin namespace: uberon def: "A zone of skin that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb skin" EXACT [OBOL:automatic] synonym: "lower limb skin" EXACT [FMA:23102] synonym: "skin of hind limb" EXACT [OBOL:automatic] synonym: "skin of hindlimb" EXACT [OBOL:automatic] synonym: "skin of lower extremity" EXACT [OBOL:automatic] synonym: "skin of lower limb" EXACT [FMA:23102] xref: EMAPA:32620 xref: FMA:23102 xref: MA:0000665 xref: NCIT:C12297 xref: SCTID:181528008 xref: UMLS:C0222268 {source="ncithesaurus:Skin_of_the_Lower_Limb_and_Hip"} is_a: UBERON:0001419 ! skin of limb intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 ! hindlimb property_value: editor_note "TODO - check free limb vs pelvic complex" xsd:string [Term] id: UBERON:0003533 name: manual digit skin namespace: uberon def: "A zone of skin that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "digit of hand skin" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb skin" EXACT [OBOL:automatic] synonym: "digitus manus skin" EXACT [OBOL:automatic] synonym: "finger skin" EXACT [OBOL:automatic] synonym: "fore limb digit skin" EXACT [OBOL:accepted] synonym: "hand digit skin" EXACT [MA:0000626] synonym: "hand digit skin" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "skin of digit of hand" EXACT [OBOL:automatic] synonym: "skin of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "skin of digitus manus" EXACT [OBOL:automatic] synonym: "skin of finger" EXACT [OBOL:automatic] synonym: "skin of hand digit" EXACT [OBOL:automatic] synonym: "skin of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit skin" EXACT [OBOL:automatic] xref: EMAPA:32648 xref: FMA:38304 xref: MA:0000626 xref: NCIT:C52720 xref: SCTID:361711001 xref: UMLS:C1708318 {source="ncithesaurus:Hand_Digit_Skin"} is_a: UBERON:0001519 ! skin of manus is_a: UBERON:0015249 ! digit skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0002389 ! manual digit [Term] id: UBERON:0003534 name: tail skin namespace: uberon def: "A zone of skin that is part of a tail [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "post-vent region skin" EXACT [OBOL:automatic] synonym: "skin of post-vent region" EXACT [OBOL:automatic] synonym: "skin of tail" EXACT [OBOL:automatic] xref: EMAPA:36502 xref: MA:0000700 xref: SCTID:67214004 is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0003538 name: right lung bronchiole namespace: uberon def: "A bronchiole that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole of right lung" EXACT [OBOL:automatic] xref: EMAPA:35425 xref: MA:0001787 xref: NCIT:C49279 xref: SCTID:200089000 xref: UMLS:C0225670 {source="ncithesaurus:Right_Lung_Bronchiole"} is_a: UBERON:0002186 ! bronchiole intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0002167 ! right lung relationship: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0003539 name: left lung bronchiole namespace: uberon def: "A bronchiole that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole of left lung" EXACT [OBOL:automatic] xref: EMAPA:19000 xref: MA:0001778 xref: NCIT:C49252 xref: SCTID:200484003 xref: UMLS:C0225674 {source="ncithesaurus:Left_Lung_Bronchiole"} is_a: UBERON:0002186 ! bronchiole intersection_of: UBERON:0002186 ! bronchiole intersection_of: part_of UBERON:0002168 ! left lung relationship: part_of UBERON:0002168 ! left lung [Term] id: UBERON:0003540 name: right lung terminal bronchiole namespace: uberon def: "A terminal bronchiole that is part of a right lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus terminalis of right lung" EXACT [OBOL:automatic] synonym: "right lung bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "terminal bronchiole of right lung" EXACT [OBOL:automatic] xref: EMAPA:36638 xref: MA:0001789 xref: NCIT:C49294 xref: UMLS:C1709961 {source="ncithesaurus:Right_Lung_Terminal_Bronchiole"} is_a: UBERON:0002187 ! terminal bronchiole is_a: UBERON:0003538 ! right lung bronchiole intersection_of: UBERON:0002187 ! terminal bronchiole intersection_of: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0003541 name: left lung terminal bronchiole namespace: uberon def: "A terminal bronchiole that is part of a left lung [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus terminalis of left lung" EXACT [OBOL:automatic] synonym: "left lung bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "terminal bronchiole of left lung" EXACT [OBOL:automatic] xref: EMAPA:36636 xref: MA:0001780 xref: NCIT:C49255 xref: UMLS:C1708675 {source="ncithesaurus:Left_Lung_Terminal_Bronchiole"} is_a: UBERON:0002187 ! terminal bronchiole is_a: UBERON:0003539 ! left lung bronchiole intersection_of: UBERON:0002187 ! terminal bronchiole intersection_of: part_of UBERON:0002168 ! left lung [Term] id: UBERON:0003544 name: brain white matter namespace: uberon def: "The regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites." [MP:0008026] subset: pheno_slim synonym: "brain white matter of neuraxis" EXACT [OBOL:automatic] synonym: "brain white substance" EXACT [OBOL:automatic] synonym: "white matter of brain" EXACT [OBOL:automatic] synonym: "white matter of neuraxis of brain" EXACT [OBOL:automatic] synonym: "white substance of brain" EXACT [OBOL:automatic] xref: EMAPA:35187 xref: HBA:9218 xref: MA:0000820 xref: NCIT:C49334 xref: UMLS:C1706995 {source="ncithesaurus:Brain_White_Matter"} is_a: UBERON:0002316 ! white matter intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0000955 ! brain relationship: contributes_to_morphology_of UBERON:0000955 ! brain relationship: part_of UBERON:0000955 ! brain [Term] id: UBERON:0003547 name: brain meninx namespace: uberon def: "A meninx that is part of a brain [Automatically generated definition]." [OBOL:automatic] subset: organ_slim subset: pheno_slim synonym: "brain meninges" EXACT [OBOL:automatic] synonym: "meninges of brain" EXACT [OBOL:automatic] synonym: "meninx of brain" EXACT [OBOL:automatic] xref: CALOHA:TS-2147 xref: EMAPA:32662 xref: EV:0100312 xref: MA:0000813 xref: SCTID:180949007 xref: VHOG:0000013 is_a: UBERON:0002360 ! meninx intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0000955 ! brain property_value: UBPROP:0000001 "Meninges that are part of the brain. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000013", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000013", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003548 name: forebrain meninges namespace: uberon def: "A meninx that is part of a forebrain [Automatically generated definition]." [OBOL:automatic] synonym: "forebrain meninx" EXACT [OBOL:automatic] synonym: "meninges of forebrain" EXACT [OBOL:automatic] synonym: "meninx of forebrain" EXACT [OBOL:automatic] xref: EMAPA:17764 xref: EMAPA:17774 xref: EMAPA:37543 {source="MA:th"} xref: MA:0000883 is_a: UBERON:0003547 ! brain meninx intersection_of: UBERON:0002360 ! meninx intersection_of: part_of UBERON:0001890 ! forebrain relationship: part_of UBERON:0001890 ! forebrain [Term] id: UBERON:0003561 name: forebrain dura mater namespace: uberon def: "A dura mater that is part of a forebrain." [OBOL:automatic] synonym: "dura mater of forebrain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of forebrain" EXACT [OBOL:automatic] synonym: "forebrain dura mater of neuraxis" EXACT [OBOL:automatic] xref: EMAPA:17766 xref: EMAPA:37545 {source="MA:th"} xref: MA:0000885 is_a: UBERON:0002092 ! brain dura mater is_a: UBERON:0003548 ! forebrain meninges intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0001890 ! forebrain [Term] id: UBERON:0003562 name: midbrain dura mater namespace: uberon def: "A dura mater that is part of a midbrain [Automatically generated definition]." [OBOL:automatic] synonym: "dura mater of midbrain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of midbrain" EXACT [OBOL:automatic] synonym: "mesencephalon dura mater" RELATED [VHOG:0000410] synonym: "midbrain dura mater of neuraxis" EXACT [OBOL:automatic] xref: EMAPA:17793 xref: MA:0001060 xref: VHOG:0000410 is_a: UBERON:0002092 ! brain dura mater is_a: UBERON:0003288 ! meninx of midbrain intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0001891 ! midbrain property_value: UBPROP:0000001 "Dura mater that is part of the midbrain. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000410", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000410", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003563 name: telencephalon dura mater namespace: uberon def: "A dura mater that is part of a telencephalon [Automatically generated definition]." [OBOL:automatic] synonym: "dura mater of neuraxis of telencephalon" EXACT [OBOL:automatic] synonym: "dura mater of telencephalon" EXACT [OBOL:automatic] synonym: "telencephalon dura mater of neuraxis" EXACT [OBOL:automatic] xref: EMAPA:17776 xref: MA:0000981 is_a: UBERON:0003289 ! meninx of telencephalon is_a: UBERON:0003561 ! forebrain dura mater intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0001893 ! telencephalon [Term] id: UBERON:0003565 name: hindbrain dura mater namespace: uberon def: "A dura mater that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] synonym: "dura mater of hindbrain" EXACT [OBOL:automatic] synonym: "dura mater of neuraxis of hindbrain" EXACT [OBOL:automatic] synonym: "hindbrain dura mater of neuraxis" EXACT [OBOL:automatic] synonym: "rhombencephalon dura mater" RELATED [VHOG:0000409] xref: EMAPA:17785 xref: MA:0000989 xref: VHOG:0000409 is_a: UBERON:0002092 ! brain dura mater is_a: UBERON:0003291 ! meninx of hindbrain intersection_of: UBERON:0002363 ! dura mater intersection_of: part_of UBERON:0002028 ! hindbrain property_value: UBPROP:0000001 "Dura mater that is part of the hindbrain. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000409", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In fishes, the meninges consist of a single membrane, the primitive meninx, wrapped around the brain and spinal cord. With the adoption of terrestrial life, the meninges doubled. In amphibians, reptiles, and birds, the meninges include a thick outer dura mater derived from mesoderm and a thin inner secondary meninx. (...) In mammals, the dura mater persists, but division of the secondary meninx yields both the arachnoid and the pia mater from ectomesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000409", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003566 name: head connective tissue namespace: uberon def: "A portion of connective tissue that is part of a head [Automatically generated definition]." [OBOL:automatic] synonym: "adult head connective tissue" EXACT [OBOL:automatic] synonym: "adult head portion of connective tissue" EXACT [OBOL:automatic] synonym: "adult head textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of adult head" EXACT [OBOL:automatic] synonym: "connective tissue of head" EXACT [OBOL:automatic] synonym: "head portion of connective tissue" EXACT [OBOL:automatic] synonym: "head textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of adult head" EXACT [OBOL:automatic] synonym: "portion of connective tissue of head" EXACT [OBOL:automatic] synonym: "textus connectivus of adult head" EXACT [OBOL:automatic] synonym: "textus connectivus of head" EXACT [OBOL:automatic] xref: EMAPA:16098 xref: MA:0000577 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000033 ! head relationship: develops_from UBERON:0005253 ! head mesenchyme relationship: part_of UBERON:0000033 ! head relationship: transformation_of UBERON:0005253 ! head mesenchyme [Term] id: UBERON:0003567 name: abdomen connective tissue namespace: uberon def: "A portion of connective tissue that is part of an abdomen [Automatically generated definition]." [OBOL:automatic] synonym: "abdomen portion of connective tissue" EXACT [OBOL:automatic] synonym: "abdomen textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of abdomen" EXACT [OBOL:automatic] synonym: "portion of connective tissue of abdomen" EXACT [OBOL:automatic] synonym: "textus connectivus of abdomen" EXACT [OBOL:automatic] xref: MA:0000519 is_a: UBERON:0003838 ! abdominal segment connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0003568 name: neck connective tissue namespace: uberon def: "A portion of connective tissue that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of neck" EXACT [OBOL:automatic] synonym: "connective tissue of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) connective tissue" EXACT [OBOL:automatic] synonym: "neck (volume) portion of connective tissue" EXACT [OBOL:automatic] synonym: "neck (volume) textus connectivus" EXACT [OBOL:automatic] synonym: "neck portion of connective tissue" EXACT [OBOL:automatic] synonym: "neck textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of neck" EXACT [OBOL:automatic] synonym: "portion of connective tissue of neck (volume)" EXACT [OBOL:automatic] synonym: "textus connectivus of neck" EXACT [OBOL:automatic] synonym: "textus connectivus of neck (volume)" EXACT [OBOL:automatic] xref: EMAPA:37250 {source="MA:th"} xref: MA:0000585 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003569 name: leg connective tissue namespace: uberon def: "A portion of connective tissue that is part of a leg [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of leg" EXACT [OBOL:automatic] synonym: "leg portion of connective tissue" EXACT [OBOL:automatic] synonym: "leg textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of leg" EXACT [OBOL:automatic] synonym: "textus connectivus of leg" EXACT [OBOL:automatic] xref: EMAPA:37324 {source="MA:th"} xref: MA:0000671 is_a: UBERON:0003589 ! hindlimb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0000978 ! leg [Term] id: UBERON:0003570 name: respiratory system connective tissue namespace: uberon def: "A portion of connective tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius portion of connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "portion of connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "portion of connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system portion of connective tissue" EXACT [OBOL:automatic] synonym: "respiratory system textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "textus connectivus of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:35968 xref: EMAPA:35977 xref: MA:0001814 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003571 name: trachea connective tissue namespace: uberon def: "A portion of connective tissue that is part of a trachea." [OBOL:automatic] subset: human_reference_atlas synonym: "connective tissue of trachea" EXACT [OBOL:automatic] synonym: "connective tissue of windpipe" EXACT [OBOL:automatic] xref: EMAPA:35876 xref: MA:0001853 is_a: UBERON:0003580 ! lower respiratory tract connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0009505 ! mesenchyme of trachea relationship: part_of UBERON:0003126 ! trachea relationship: transformation_of UBERON:0009505 ! mesenchyme of trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003573 name: arm connective tissue namespace: uberon def: "A portion of connective tissue that is part of an arm [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37316 {source="MA:th"} xref: MA:0000593 is_a: UBERON:0003588 ! forelimb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm [Term] id: UBERON:0003574 name: elbow connective tissue namespace: uberon def: "A portion of connective tissue that is part of a elbow [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of cubital region" EXACT [OBOL:automatic] synonym: "connective tissue of elbow" EXACT [OBOL:automatic] synonym: "textus connectivus of cubital region" EXACT [OBOL:automatic] xref: EMAPA:37318 {source="MA:th"} xref: MA:0000609 is_a: UBERON:0003573 ! arm connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001461 ! elbow relationship: develops_from UBERON:0003318 ! mesenchyme of elbow relationship: part_of UBERON:0001461 ! elbow relationship: transformation_of UBERON:0003318 ! mesenchyme of elbow [Term] id: UBERON:0003575 name: wrist connective tissue namespace: uberon def: "A portion of connective tissue that is part of a wrist [Automatically generated definition]." [OBOL:automatic] synonym: "carpal region connective tissue" EXACT [OBOL:automatic] synonym: "connective tissue of carpal region" EXACT [OBOL:automatic] synonym: "connective tissue of wrist" EXACT [OBOL:automatic] xref: EMAPA:37320 {source="MA:th"} xref: MA:0000636 is_a: UBERON:0003598 ! manus connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0004452 ! carpal region relationship: develops_from UBERON:0003319 ! mesenchyme of carpal region relationship: part_of UBERON:0004452 ! carpal region relationship: transformation_of UBERON:0003319 ! mesenchyme of carpal region [Term] id: UBERON:0003576 name: hip connective tissue namespace: uberon def: "A portion of connective tissue that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of hip" EXACT [OBOL:automatic] synonym: "connective tissue of hip region" EXACT [OBOL:automatic] synonym: "connective tissue of regio coxae" EXACT [OBOL:automatic] xref: EMAPA:37323 {source="MA:th"} xref: MA:0000656 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001464 ! hip relationship: develops_from UBERON:0003320 ! mesenchyme of hip relationship: part_of UBERON:0001464 ! hip relationship: transformation_of UBERON:0003320 ! mesenchyme of hip [Term] id: UBERON:0003577 name: knee connective tissue namespace: uberon def: "A portion of connective tissue that is part of a knee [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of knee" EXACT [OBOL:automatic] synonym: "knee portion of connective tissue" EXACT [OBOL:automatic] xref: EMAPA:37326 {source="MA:th"} xref: MA:0000667 is_a: UBERON:0003569 ! leg connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001465 ! knee relationship: develops_from UBERON:0003321 ! mesenchyme of knee relationship: part_of UBERON:0001465 ! knee relationship: transformation_of UBERON:0003321 ! mesenchyme of knee [Term] id: UBERON:0003578 name: pedal digit connective tissue namespace: uberon def: "A portion of connective tissue that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of digit of foot" EXACT [OBOL:automatic] synonym: "connective tissue of digitus pedis" EXACT [OBOL:automatic] synonym: "connective tissue of foot digit" EXACT [OBOL:automatic] synonym: "connective tissue of toe" EXACT [OBOL:automatic] synonym: "digitus pedis textus connectivus" EXACT [OBOL:automatic] synonym: "foot digit connective tissue" EXACT [MA:0000647] synonym: "foot digit connective tissue" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit connective tissue" EXACT [OBOL:accepted] xref: EMAPA:37330 {source="MA:th"} xref: MA:0000647 is_a: UBERON:0003595 ! pes connective tissue is_a: UBERON:0015791 ! digit connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001466 ! pedal digit relationship: develops_from UBERON:0005255 ! pedal digit mesenchyme relationship: part_of UBERON:0001466 ! pedal digit relationship: transformation_of UBERON:0005255 ! pedal digit mesenchyme [Term] id: UBERON:0003579 name: shoulder connective tissue namespace: uberon def: "A portion of connective tissue that is part of a shoulder [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of shoulder" EXACT [OBOL:automatic] synonym: "portion of connective tissue of shoulder" EXACT [OBOL:automatic] synonym: "shoulder portion of connective tissue" EXACT [OBOL:automatic] synonym: "shoulder textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of shoulder" EXACT [OBOL:automatic] xref: EMAPA:37315 {source="MA:th"} xref: MA:0000632 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001467 ! shoulder relationship: develops_from UBERON:0003322 ! mesenchyme of shoulder relationship: part_of UBERON:0001467 ! shoulder relationship: transformation_of UBERON:0003322 ! mesenchyme of shoulder [Term] id: UBERON:0003580 name: lower respiratory tract connective tissue namespace: uberon def: "A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract portion of connective tissue" EXACT [OBOL:automatic] synonym: "lower respiratory tract textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "textus connectivus of lower respiratory tract" EXACT [OBOL:automatic] xref: EMAPA:37548 {source="MA:th"} xref: MA:0002409 is_a: UBERON:0003570 ! respiratory system connective tissue is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001558 ! lower respiratory tract relationship: part_of UBERON:0001558 ! lower respiratory tract [Term] id: UBERON:0003582 name: nasopharynx connective tissue namespace: uberon def: "A portion of connective tissue that is part of a nasopharynx [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "connective tissue of nasopharynx" EXACT [OBOL:automatic] synonym: "connective tissue of rhinopharynx" EXACT [OBOL:automatic] synonym: "nasal part of pharynx connective tissue" EXACT [OBOL:automatic] synonym: "nasal part of pharynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "nasal part of pharynx textus connectivus" EXACT [OBOL:automatic] synonym: "nasopharynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "nasopharynx textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "portion of connective tissue of nasopharynx" EXACT [OBOL:automatic] synonym: "portion of connective tissue of rhinopharynx" EXACT [OBOL:automatic] synonym: "rhinopharynx connective tissue" EXACT [OBOL:automatic] synonym: "rhinopharynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "rhinopharynx textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "textus connectivus of nasopharynx" EXACT [OBOL:automatic] synonym: "textus connectivus of rhinopharynx" EXACT [OBOL:automatic] xref: EMAPA:37682 {source="MA:th"} xref: MA:0001864 is_a: UBERON:0003570 ! respiratory system connective tissue is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001728 ! nasopharynx [Term] id: UBERON:0003583 name: larynx connective tissue namespace: uberon def: "A portion of connective tissue that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of larynx" EXACT [OBOL:automatic] synonym: "laryngeal connective tissue" RELATED [EMAPA:35471] synonym: "larynx portion of connective tissue" EXACT [OBOL:automatic] synonym: "larynx textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of larynx" EXACT [OBOL:automatic] synonym: "textus connectivus of larynx" EXACT [OBOL:automatic] xref: EMAPA:35471 xref: MA:0001754 xref: NCIT:C49245 xref: UMLS:C1708651 {source="ncithesaurus:Laryngeal_Connective_Tissue"} is_a: UBERON:0003570 ! respiratory system connective tissue is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001737 ! larynx [Term] id: UBERON:0003585 name: dermis connective tissue namespace: uberon def: "A portion of connective tissue that is part of a dermis [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "connective tissue of dermis" EXACT [OBOL:automatic] synonym: "dermis portion of connective tissue" EXACT [OBOL:automatic] synonym: "dermis textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of dermis" EXACT [OBOL:automatic] synonym: "textus connectivus of dermis" EXACT [OBOL:automatic] xref: EMAPA:36509 xref: MA:0000799 is_a: UBERON:0002384 ! connective tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002067 ! dermis relationship: develops_from UBERON:0004016 ! dermatome relationship: part_of UBERON:0002067 ! dermis [Term] id: UBERON:0003586 name: trunk connective tissue namespace: uberon def: "A portion of connective tissue that is part of a trunk [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of torso" EXACT [OBOL:automatic] synonym: "connective tissue of trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of torso" EXACT [OBOL:automatic] synonym: "portion of connective tissue of trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of torso" EXACT [OBOL:automatic] synonym: "textus connectivus of trunk" EXACT [OBOL:automatic] synonym: "torso connective tissue" EXACT [OBOL:automatic] synonym: "torso portion of connective tissue" EXACT [OBOL:automatic] synonym: "torso textus connectivus" EXACT [OBOL:automatic] synonym: "trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "trunk textus connectivus" EXACT [OBOL:automatic] xref: EMAPA:37252 {source="MA:th"} xref: MA:0000513 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0003587 name: limb connective tissue namespace: uberon def: "A portion of connective tissue that is part of a limb [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of limb" EXACT [OBOL:automatic] synonym: "limb portion of connective tissue" EXACT [OBOL:automatic] synonym: "limb textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of limb" EXACT [OBOL:automatic] synonym: "textus connectivus of limb" EXACT [OBOL:automatic] xref: EMAPA:37313 {source="MA:th"} xref: MA:0000689 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002101 ! limb relationship: develops_from UBERON:0009749 ! limb mesenchyme relationship: part_of UBERON:0002101 ! limb relationship: transformation_of UBERON:0009749 ! limb mesenchyme [Term] id: UBERON:0003588 name: forelimb connective tissue namespace: uberon def: "A portion of connective tissue that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of anteriormost limb" EXACT [OBOL:automatic] synonym: "connective tissue of fore limb" EXACT [OBOL:automatic] synonym: "connective tissue of forelimb" EXACT [OBOL:automatic] synonym: "connective tissue of superior member" EXACT [OBOL:automatic] synonym: "connective tissue of upper extremity" EXACT [OBOL:automatic] synonym: "wing connective tissue" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:37314 {source="MA:th"} xref: MA:0000613 is_a: UBERON:0003587 ! limb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002102 ! forelimb relationship: develops_from UBERON:0003859 ! forelimb mesenchyme relationship: part_of UBERON:0002102 ! forelimb relationship: transformation_of UBERON:0003859 ! forelimb mesenchyme [Term] id: UBERON:0003589 name: hindlimb connective tissue namespace: uberon def: "A portion of connective tissue that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of hind limb" EXACT [OBOL:automatic] synonym: "connective tissue of hindlimb" EXACT [OBOL:automatic] synonym: "connective tissue of inferior member" EXACT [OBOL:automatic] synonym: "connective tissue of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb connective tissue" EXACT [OBOL:automatic] xref: EMAPA:37322 {source="MA:th"} xref: MA:0000661 is_a: UBERON:0003587 ! limb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002103 ! hindlimb relationship: develops_from UBERON:0003860 ! hindlimb mesenchyme relationship: part_of UBERON:0002103 ! hindlimb relationship: transformation_of UBERON:0003860 ! hindlimb mesenchyme [Term] id: UBERON:0003592 name: bronchus connective tissue namespace: uberon def: "A portion of connective tissue that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "bronchi connective tissue" EXACT [OBOL:automatic] synonym: "bronchi portion of connective tissue" EXACT [OBOL:automatic] synonym: "bronchi textus connectivus" EXACT [OBOL:automatic] synonym: "bronchial connective tissue" RELATED [EMAPA:35193] synonym: "bronchial mesenchyme" RELATED [EMAPA:32690] synonym: "bronchial trunk connective tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk textus connectivus" EXACT [OBOL:automatic] synonym: "bronchus portion of connective tissue" EXACT [OBOL:automatic] synonym: "bronchus textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of bronchi" EXACT [OBOL:automatic] synonym: "connective tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "connective tissue of bronchus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of bronchi" EXACT [OBOL:automatic] synonym: "portion of connective tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of bronchus" EXACT [OBOL:automatic] synonym: "textus connectivus of bronchi" EXACT [OBOL:automatic] synonym: "textus connectivus of bronchial trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of bronchus" EXACT [OBOL:automatic] xref: EMAPA:32690 xref: EMAPA:35193 xref: MA:0001831 xref: NCIT:C49210 xref: UMLS:C1707052 {source="ncithesaurus:Bronchus_Connective_Tissue"} is_a: UBERON:0003580 ! lower respiratory tract connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 ! bronchus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003593 name: thoracic cavity connective tissue namespace: uberon def: "A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of chest connective tissue" EXACT [OBOL:automatic] synonym: "cavity of chest portion of connective tissue" EXACT [OBOL:automatic] synonym: "cavity of chest textus connectivus" EXACT [OBOL:automatic] synonym: "cavity of thorax connective tissue" EXACT [OBOL:automatic] synonym: "cavity of thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "cavity of thorax textus connectivus" EXACT [OBOL:automatic] synonym: "chest cavity connective tissue" EXACT [OBOL:automatic] synonym: "chest cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "chest cavity textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of cavity of chest" EXACT [OBOL:automatic] synonym: "connective tissue of cavity of thorax" EXACT [OBOL:automatic] synonym: "connective tissue of chest cavity" EXACT [OBOL:automatic] synonym: "connective tissue of pectoral cavity" EXACT [OBOL:automatic] synonym: "connective tissue of thoracic cavity" EXACT [OBOL:automatic] synonym: "pectoral cavity connective tissue" EXACT [OBOL:automatic] synonym: "pectoral cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "pectoral cavity textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of cavity of chest" EXACT [OBOL:automatic] synonym: "portion of connective tissue of cavity of thorax" EXACT [OBOL:automatic] synonym: "portion of connective tissue of chest cavity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of pectoral cavity" EXACT [OBOL:automatic] synonym: "portion of connective tissue of thoracic cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of cavity of chest" EXACT [OBOL:automatic] synonym: "textus connectivus of cavity of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of chest cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of pectoral cavity" EXACT [OBOL:automatic] synonym: "textus connectivus of thoracic cavity" EXACT [OBOL:automatic] synonym: "thoracic cavity portion of connective tissue" EXACT [OBOL:automatic] synonym: "thoracic cavity textus connectivus" EXACT [OBOL:automatic] xref: EMAPA:37255 {source="MA:th"} xref: MA:0000555 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: located_in UBERON:0002224 ! thoracic cavity relationship: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0003594 name: pelvis connective tissue namespace: uberon def: "A portion of connective tissue that is part of a pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of pelvis" EXACT [OBOL:automatic] synonym: "pelvis portion of connective tissue" EXACT [OBOL:automatic] synonym: "pelvis textus connectivus" EXACT [OBOL:automatic] synonym: "portion of connective tissue of pelvis" EXACT [OBOL:automatic] synonym: "textus connectivus of pelvis" EXACT [OBOL:automatic] xref: EMAPA:37257 {source="MA:th"} xref: MA:0000533 is_a: UBERON:0003838 ! abdominal segment connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002355 ! pelvic region of trunk [Term] id: UBERON:0003595 name: pes connective tissue namespace: uberon def: "A portion of connective tissue that is part of a foot [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of foot" EXACT [OBOL:automatic] synonym: "connective tissue of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "foot connective tissue" EXACT [MA:0000644] synonym: "textus connectivus of pes" EXACT LATIN [OBOL:automatic] xref: EMAPA:37329 {source="MA:th"} xref: MA:0000644 is_a: UBERON:0003589 ! hindlimb connective tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002387 ! pes relationship: develops_from UBERON:0003328 ! mesenchyme of footplate relationship: part_of UBERON:0002387 ! pes relationship: transformation_of UBERON:0003328 ! mesenchyme of footplate [Term] id: UBERON:0003596 name: ankle connective tissue namespace: uberon def: "A portion of connective tissue that is part of an ankle [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of ankle" EXACT [OBOL:automatic] synonym: "tarsal region connective tissue" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37328 {source="MA:th"} xref: MA:0000639 is_a: UBERON:0003595 ! pes connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0004454 ! tarsal region relationship: develops_from UBERON:0010695 ! mesenchyme of tarsal region relationship: part_of UBERON:0004454 ! tarsal region relationship: transformation_of UBERON:0010695 ! mesenchyme of tarsal region [Term] id: UBERON:0003597 name: manual digit connective tissue namespace: uberon def: "A portion of connective tissue that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of digit of hand" EXACT [OBOL:automatic] synonym: "connective tissue of digitus manus" EXACT [OBOL:automatic] synonym: "connective tissue of finger" EXACT [OBOL:automatic] synonym: "connective tissue of hand digit" EXACT [OBOL:automatic] synonym: "fore limb digit connective tissue" EXACT [OBOL:accepted] synonym: "hand digit connective tissue" EXACT [MA:0000623] synonym: "hand digit connective tissue" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] xref: EMAPA:37321 {source="MA:th"} xref: MA:0000623 is_a: UBERON:0003598 ! manus connective tissue is_a: UBERON:0015791 ! digit connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002389 ! manual digit relationship: develops_from UBERON:0005257 ! manual digit mesenchyme relationship: part_of UBERON:0002389 ! manual digit relationship: transformation_of UBERON:0005257 ! manual digit mesenchyme [Term] id: UBERON:0003598 name: manus connective tissue namespace: uberon def: "A portion of connective tissue that is part of a hand [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of hand" EXACT [OBOL:automatic] synonym: "connective tissue of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "hand connective tissue" EXACT [MA:0000620] xref: EMAPA:35392 xref: MA:0000620 is_a: UBERON:0003588 ! forelimb connective tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002398 ! manus relationship: develops_from UBERON:0009523 ! mesenchyme of handplate relationship: part_of UBERON:0002398 ! manus relationship: transformation_of UBERON:0009523 ! mesenchyme of handplate [Term] id: UBERON:0003599 name: tail connective tissue namespace: uberon def: "A portion of connective tissue that is part of a tail [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of post-vent region" EXACT [OBOL:automatic] synonym: "connective tissue of tail" EXACT [OBOL:automatic] synonym: "portion of connective tissue of post-vent region" EXACT [OBOL:automatic] synonym: "portion of connective tissue of tail" EXACT [OBOL:automatic] synonym: "post-vent region connective tissue" EXACT [OBOL:automatic] synonym: "post-vent region portion of connective tissue" EXACT [OBOL:automatic] synonym: "post-vent region textus connectivus" EXACT [OBOL:automatic] synonym: "tail portion of connective tissue" EXACT [OBOL:automatic] synonym: "tail textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of post-vent region" EXACT [OBOL:automatic] synonym: "textus connectivus of tail" EXACT [OBOL:automatic] xref: EMAPA:16749 xref: MA:0000697 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0003601 name: neck cartilage namespace: uberon def: "A cartilage that is part of a neck [Automatically generated definition]." [OBOL:automatic] synonym: "cartilage of neck" EXACT [OBOL:automatic] synonym: "cartilage of neck (volume)" EXACT [OBOL:automatic] synonym: "neck (volume) cartilage" EXACT [OBOL:automatic] xref: EMAPA:37251 {source="MA:th"} xref: MA:0000586 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0003603 name: lower respiratory tract cartilage namespace: uberon def: "A cartilage that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "cartilage of lower respiratory tract" EXACT [OBOL:automatic] xref: EMAPA:37547 {source="MA:th"} xref: MA:0001819 xref: NCIT:C49256 xref: UMLS:C1708759 {source="ncithesaurus:Lower_Respiratory_Tract_Cartilage"} is_a: UBERON:0003406 ! cartilage of respiratory system is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0001558 ! lower respiratory tract relationship: part_of UBERON:0001558 ! lower respiratory tract [Term] id: UBERON:0003604 name: trachea cartilage namespace: uberon def: "The ring-shaped cartilaginous structures that support the trachea." [http://orcid.org/0000-0002-6601-2165, J:97123, MGI:smb, MP:0003120] subset: human_reference_atlas subset: pheno_slim synonym: "cartilage of the trachea" RELATED [Wikipedia:Tracheal_rings] synonym: "cartilage of trachea" EXACT [OBOL:automatic] synonym: "cartilage of windpipe" EXACT [OBOL:automatic] synonym: "cartilagines tracheales" RELATED LATIN [Wikipedia:Tracheal_rings] synonym: "cartilaginous ring of trachea" EXACT [EMAPA:18699] synonym: "cartilaginous trachea cartilage" EXACT [OBOL:automatic] synonym: "cartilago trachealis" EXACT [FMA:7434] synonym: "ring of the trachea" RELATED [Wikipedia:Tracheal_rings] synonym: "trachea ring" RELATED [] synonym: "tracheal cartilage" EXACT [FMA:7434] synonym: "tracheal ring" RELATED [Wikipedia:Tracheal_rings] synonym: "windpipe cartilage" EXACT [OBOL:automatic] xref: EMAPA:18699 xref: EMAPA:35875 xref: FMA:7434 xref: MA:0001857 xref: NCIT:C49304 xref: SCTID:278979006 xref: UMLS:C1710456 {source="ncithesaurus:Trachea_Cartilage"} xref: Wikipedia:Tracheal_rings is_a: UBERON:0003603 ! lower respiratory tract cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0007267 ! trachea pre-cartilage rings relationship: part_of UBERON:0003126 ! trachea property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/56/Gray952.png" xsd:anyURI property_value: editor_note "check whether to classify as part of splanchoncranium" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "in mammals the rings are incomplete, in avians the rings are complete." xsd:string [Term] id: UBERON:0003605 name: eye skin gland namespace: uberon def: "A skin gland that is part of a camera-type eye [Automatically generated definition]." [OBOL:automatic] subset: organ_slim synonym: "camera-type eye skin gland" EXACT [OBOL:automatic] synonym: "camera-type eye skin glands" EXACT [OBOL:automatic] synonym: "camera-type eye skin glands set" EXACT [OBOL:automatic] synonym: "skin gland of camera-type eye" EXACT [OBOL:automatic] synonym: "skin gland of vertebrate eye" EXACT [OBOL:automatic] synonym: "skin glands of camera-type eye" EXACT [OBOL:automatic] synonym: "skin glands of vertebrate eye" EXACT [OBOL:automatic] synonym: "skin glands set of camera-type eye" EXACT [OBOL:automatic] synonym: "skin glands set of vertebrate eye" EXACT [OBOL:automatic] synonym: "vertebrate eye skin gland" EXACT [OBOL:automatic] synonym: "vertebrate eye skin glands" EXACT [OBOL:automatic] synonym: "vertebrate eye skin glands set" EXACT [OBOL:automatic] xref: EMAPA:37530 {source="MA:th"} xref: MA:0002451 is_a: UBERON:0002419 ! skin gland is_a: UBERON:0004859 ! eye gland is_a: UBERON:0015152 ! gland of ocular region intersection_of: UBERON:0002419 ! skin gland intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0003606 name: limb long bone namespace: uberon def: "A long bone that is part of a limb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "long bone of limb" EXACT [OBOL:automatic] xref: EMAPA:35495 xref: MA:0000298 is_a: UBERON:0002428 ! limb bone is_a: UBERON:0002495 ! long bone intersection_of: UBERON:0002495 ! long bone intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0003607 name: forelimb long bone namespace: uberon def: "A long bone that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "anteriormost limb long bone" EXACT [OBOL:automatic] synonym: "fore limb long bone" EXACT [OBOL:automatic] synonym: "long bone of anteriormost limb" EXACT [OBOL:automatic] synonym: "long bone of fore limb" EXACT [OBOL:automatic] synonym: "long bone of forelimb" EXACT [OBOL:automatic] synonym: "long bone of superior member" EXACT [OBOL:automatic] synonym: "long bone of upper extremity" EXACT [OBOL:automatic] synonym: "superior member long bone" EXACT [OBOL:automatic] synonym: "upper extremity long bone" EXACT [OBOL:automatic] synonym: "wing long bone" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:35350 xref: MA:0000299 is_a: UBERON:0003606 ! limb long bone is_a: UBERON:0008962 ! forelimb bone intersection_of: UBERON:0002495 ! long bone intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003608 name: hindlimb long bone namespace: uberon def: "A long bone that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb long bone" EXACT [OBOL:automatic] synonym: "inferior member long bone" EXACT [OBOL:automatic] synonym: "long bone of hind limb" EXACT [OBOL:automatic] synonym: "long bone of hindlimb" EXACT [OBOL:automatic] synonym: "long bone of inferior member" EXACT [OBOL:automatic] synonym: "long bone of lower extremity" EXACT [OBOL:automatic] synonym: "lower extremity long bone" EXACT [OBOL:automatic] xref: EMAPA:35403 xref: MA:0000300 is_a: UBERON:0003464 ! hindlimb bone is_a: UBERON:0003606 ! limb long bone intersection_of: UBERON:0002495 ! long bone intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003609 name: aorta elastic tissue namespace: uberon def: "The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall." [MP:0009862] subset: pheno_slim synonym: "adult aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "adult aorta elastic tissue" EXACT [OBOL:automatic] synonym: "adult aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "aorta elastic lamina" EXACT [MP:0009862] synonym: "aorta elastic laminae" EXACT PLURAL [MP:0009862] synonym: "aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "dorsal aorta elastic connective tissue" EXACT [OBOL:automatic] synonym: "dorsal aorta elastic tissue" EXACT [OBOL:automatic] synonym: "dorsal aorta textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of adult aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of dorsal aorta" EXACT [OBOL:automatic] synonym: "elastic connective tissue of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "elastic tissue of adult aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of dorsal aorta" EXACT [OBOL:automatic] synonym: "elastic tissue of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of adult aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of dorsal aorta" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "trunk of aortic tree elastic connective tissue" EXACT [OBOL:automatic] synonym: "trunk of aortic tree elastic tissue" EXACT [OBOL:automatic] synonym: "trunk of aortic tree textus connectivus elasticus" EXACT [OBOL:automatic] xref: MA:0002859 is_a: UBERON:0003614 ! blood vessel elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0000947 ! aorta relationship: part_of UBERON:0000947 ! aorta [Term] id: UBERON:0003610 name: heart elastic tissue namespace: uberon def: "The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers." [MP:0009863] subset: pheno_slim synonym: "cardiac elastic tissue" EXACT [MP:0009863] synonym: "elastic connective tissue of heart" EXACT [OBOL:automatic] synonym: "elastic tissue of heart" EXACT [OBOL:automatic] synonym: "heart elastic connective tissue" EXACT [OBOL:automatic] synonym: "heart textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of heart" EXACT [OBOL:automatic] xref: MA:0002858 is_a: UBERON:0003613 ! cardiovascular system elastic tissue is_a: UBERON:0003837 ! thoracic segment connective tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart [Term] id: UBERON:0003611 name: respiratory system elastic tissue namespace: uberon def: "An elastic tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius elastic connective tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius elastic tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "elastic connective tissue of respiratory system" EXACT [OBOL:automatic] synonym: "elastic tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "elastic tissue of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system elastic connective tissue" EXACT [OBOL:automatic] synonym: "respiratory system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37579 {source="MA:th"} xref: MA:0001820 is_a: UBERON:0002521 ! elastic tissue is_a: UBERON:0003570 ! respiratory system connective tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0004777 ! respiratory system submucosa [Term] id: UBERON:0003613 name: cardiovascular system elastic tissue namespace: uberon def: "An elastic tissue that is part of a circulatory system [Automatically generated definition]." [OBOL:automatic] synonym: "cardiovascular system elastic connective tissue" EXACT [OBOL:automatic] synonym: "cardiovascular system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "circulatory system elastic connective tissue" EXACT [OBOL:automatic] synonym: "circulatory system elastic tissue" EXACT [OBOL:automatic] synonym: "circulatory system textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of cardiovascular system" EXACT [OBOL:automatic] synonym: "elastic connective tissue of circulatory system" EXACT [OBOL:automatic] synonym: "elastic tissue of cardiovascular system" EXACT [OBOL:automatic] synonym: "elastic tissue of circulatory system" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of cardiovascular system" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of circulatory system" EXACT [OBOL:automatic] xref: MA:0002857 is_a: UBERON:0002521 ! elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0001009 ! circulatory system relationship: part_of UBERON:0004535 ! cardiovascular system [Term] id: UBERON:0003614 name: blood vessel elastic tissue namespace: uberon def: "Elastic tissue layer that lines a blood vessel layer." [http://orcid.org/0000-0002-6601-2165, https://sourceforge.net/p/obo/mammalian-phenotype-requests/2026/] subset: pheno_slim synonym: "blood vessel elastic connective tissue" EXACT [OBOL:automatic] synonym: "blood vessel textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of blood vessel" EXACT [OBOL:automatic] synonym: "elastic lamina" BROAD [MP:0006083] synonym: "elastic laminae" BROAD PLURAL [MP:0006083] synonym: "elastic tissue of blood vessel" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of blood vessel" EXACT [OBOL:automatic] synonym: "vascular elastic lamina" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "vascular elastic laminae" EXACT PLURAL [http://orcid.org/0000-0002-6601-2165] synonym: "vascular elastic tissue" EXACT [MP:0006083] xref: EMAPA:36300 xref: MA:0002856 is_a: UBERON:0003613 ! cardiovascular system elastic tissue is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel [Term] id: UBERON:0003615 name: lung elastic tissue namespace: uberon def: "Elastic tissue that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "elastic connective tissue of lung" EXACT [OBOL:automatic] synonym: "elastic tissue of lung" EXACT [OBOL:automatic] synonym: "lung elastic connective tissue" EXACT [OBOL:automatic] synonym: "lung textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "pulmonary elastic fiber" NARROW [http://orcid.org/0000-0002-6601-2165] synonym: "textus connectivus elasticus of lung" EXACT [OBOL:automatic] xref: MA:0002860 is_a: UBERON:0000114 ! lung connective tissue is_a: UBERON:0003611 ! respiratory system elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0002048 ! lung [Term] id: UBERON:0003616 name: bronchus elastic tissue namespace: uberon def: "An elastic tissue that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] synonym: "bronchi elastic connective tissue" EXACT [OBOL:automatic] synonym: "bronchi elastic tissue" EXACT [OBOL:automatic] synonym: "bronchi textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "bronchial trunk elastic connective tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk elastic tissue" EXACT [OBOL:automatic] synonym: "bronchial trunk textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "bronchus elastic connective tissue" EXACT [OBOL:automatic] synonym: "bronchus textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of bronchi" EXACT [OBOL:automatic] synonym: "elastic connective tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "elastic connective tissue of bronchus" EXACT [OBOL:automatic] synonym: "elastic tissue of bronchi" EXACT [OBOL:automatic] synonym: "elastic tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "elastic tissue of bronchus" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of bronchi" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of bronchial trunk" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of bronchus" EXACT [OBOL:automatic] xref: MA:0001838 xref: NCIT:C49211 xref: UMLS:C1707053 {source="ncithesaurus:Bronchus_Elastic_Tissue"} is_a: UBERON:0003592 ! bronchus connective tissue is_a: UBERON:0003611 ! respiratory system elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0001957 ! submucosa of bronchus [Term] id: UBERON:0003617 name: trachea elastic tissue namespace: uberon def: "An elastic tissue that is part of a trachea [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "cartilaginous trachea elastic connective tissue" EXACT [OBOL:automatic] synonym: "cartilaginous trachea elastic tissue" EXACT [OBOL:automatic] synonym: "cartilaginous trachea textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "elastic connective tissue of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "elastic connective tissue of vertebrate trachea" EXACT [OBOL:automatic] synonym: "elastic connective tissue of windpipe" EXACT [OBOL:automatic] synonym: "elastic tissue of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "elastic tissue of vertebrate trachea" EXACT [OBOL:automatic] synonym: "elastic tissue of windpipe" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of vertebrate trachea" EXACT [OBOL:automatic] synonym: "textus connectivus elasticus of windpipe" EXACT [OBOL:automatic] synonym: "vertebrate trachea elastic connective tissue" EXACT [OBOL:automatic] synonym: "vertebrate trachea elastic tissue" EXACT [OBOL:automatic] synonym: "vertebrate trachea textus connectivus elasticus" EXACT [OBOL:automatic] synonym: "windpipe elastic connective tissue" EXACT [OBOL:automatic] synonym: "windpipe elastic tissue" EXACT [OBOL:automatic] synonym: "windpipe textus connectivus elasticus" EXACT [OBOL:automatic] xref: MA:0001861 is_a: UBERON:0003571 ! trachea connective tissue is_a: UBERON:0003611 ! respiratory system elastic tissue intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0002202 ! submucosa of trachea property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003618 name: aorta tunica media namespace: uberon def: "The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers." [MP:0009873] subset: pheno_slim synonym: "adult aorta tunica media" EXACT [OBOL:automatic] synonym: "dorsal aorta tunica media" EXACT [OBOL:automatic] synonym: "trunk of aortic tree tunica media" EXACT [OBOL:automatic] synonym: "tunica media of adult aorta" EXACT [OBOL:automatic] synonym: "tunica media of aorta" EXACT [OBOL:automatic] synonym: "tunica media of dorsal aorta" EXACT [OBOL:automatic] synonym: "tunica media of trunk of aortic tree" EXACT [OBOL:automatic] xref: EMAPA:35138 xref: FMA:74433 xref: MA:0002903 xref: SCTID:48467007 is_a: UBERON:0002522 ! tunica media intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0000947 ! aorta relationship: contributes_to_morphology_of UBERON:0004663 ! aorta wall relationship: part_of UBERON:0004663 ! aorta wall [Term] id: UBERON:0003619 name: aorta tunica intima namespace: uberon def: "The innermost layer of the aorta, containing the endothelium and an inner elastic membrane." [MP:0009872] subset: pheno_slim synonym: "adult aorta tunica intima" EXACT [OBOL:automatic] synonym: "dorsal aorta tunica intima" EXACT [OBOL:automatic] synonym: "trunk of aortic tree tunica intima" EXACT [OBOL:automatic] synonym: "tunica intima of adult aorta" EXACT [OBOL:automatic] synonym: "tunica intima of aorta" EXACT [OBOL:automatic] synonym: "tunica intima of dorsal aorta" EXACT [OBOL:automatic] synonym: "tunica intima of trunk of aortic tree" EXACT [OBOL:automatic] xref: BTO:0005553 xref: EMAPA:35137 xref: FMA:74419 xref: MA:0002904 xref: SCTID:362031007 is_a: UBERON:0002523 ! tunica intima is_a: UBERON:0004797 ! blood vessel layer intersection_of: UBERON:0002523 ! tunica intima intersection_of: part_of UBERON:0000947 ! aorta relationship: contributes_to_morphology_of UBERON:0004663 ! aorta wall relationship: part_of UBERON:0004663 ! aorta wall [Term] id: UBERON:0003620 name: manual digit 1 phalanx namespace: uberon def: "A phalanx that is part of a hand digit 1 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "fore limb digit 1 phalanx" EXACT [OBOL:accepted] synonym: "hand digit 1 phalanx" EXACT [MA:0001389] synonym: "hand digit 1 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit I phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of hand digit 1" EXACT [OBOL:automatic] synonym: "phalanx of thumb" EXACT [OBOL:automatic] synonym: "thumb phalanx" EXACT [OBOL:automatic] xref: EMAPA:19113 xref: FMA:35477 xref: MA:0001389 xref: NCIT:C52777 xref: SCTID:181975002 xref: UMLS:C1711344 {source="ncithesaurus:Hand_Digit_1_Phalanx"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0015025 ! manual digit 1 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: develops_from UBERON:0010675 ! manual digit 1 phalanx cartilage element [Term] id: UBERON:0003622 name: manual digit 2 namespace: uberon def: "2nd digit of the manus." [Wikipedia:Index_finger] subset: pheno_slim synonym: "2nd digit of hand" EXACT [] synonym: "2nd finger" EXACT [] synonym: "digit 2 of fore-paw" EXACT [EMAPA:17432] synonym: "finger 2" EXACT [EHDAA2:0000517] synonym: "fore digit II" EXACT [AAO:0010640] synonym: "fore limb digit 2" EXACT [OBOL:accepted] synonym: "hand digit 2" EXACT [MA:0000455] synonym: "hand digit 2" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "index finger" NARROW [] synonym: "manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "second digit of hand" EXACT [FMA:24946] synonym: "second finger" EXACT [] xref: AAO:0010640 xref: EHDAA2:0000517 xref: EMAPA:17432 xref: FMA:24946 xref: MA:0000455 xref: NCIT:C52835 xref: SCTID:362758006 xref: UMLS:C0230388 {source="ncithesaurus:Hand_Digit_2"} xref: Wikipedia:Index_finger is_a: UBERON:0006049 ! digit 2 is_a: UBERON:0019232 ! manual digit 2, 3 or 4 intersection_of: UBERON:0006049 ! digit 2 intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:5003622 ! manual digit 2 plus metapodial segment property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/d5/Index_finger.JPG" xsd:anyURI property_value: RO:0002173 NCBITaxon:8782 property_value: UBPROP:0000007 "indicis" xsd:string property_value: UBPROP:0000008 "Anurans lack manual digit 1, so manual digit 2 is the digit after the prepollex (Phenotype RCN Oct 2012)" xsd:string property_value: UBPROP:0000008 "This class represents the standard tetrapod configuration. Wagner proposes that avian digits I,II,III develop from C2,C3,C4. To support this scheme we have separate classes representing the avian digits (here called alula, manual digit, major digit)." xsd:string {scope="NCBITaxon:8782", seeAlso="UBERON:0012261", source="PMID:10220427", source="PhenoscapeRCN"} [Term] id: UBERON:0003623 name: manual digit 3 namespace: uberon def: "3rd digit of the manus." [Wikipedia:Middle_finger] subset: pheno_slim synonym: "3rd digit of hand" EXACT [] synonym: "3rd finger" EXACT [] synonym: "digit 3 of fore-paw" EXACT [EMAPA:17435] synonym: "digitus medius" RELATED LATIN [Wikipedia:Middle_finger] synonym: "finger 3" EXACT [EHDAA2:0000523] synonym: "fore digit III" EXACT [AAO:0010641] synonym: "fore limb digit 3" EXACT [OBOL:accepted] synonym: "hand digit 3" EXACT [MA:0000456] synonym: "hand digit 3" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "long finger" RELATED [EMAPA:17435] synonym: "manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle finger" NARROW [] synonym: "third digit of hand" EXACT [FMA:24947] synonym: "third finger" EXACT [] xref: AAO:0010641 xref: EHDAA2:0000523 xref: EMAPA:17435 xref: FMA:24947 xref: MA:0000456 xref: NCIT:C52836 xref: SCTID:362763005 xref: UMLS:C0230393 {source="ncithesaurus:Hand_Digit_3"} xref: Wikipedia:Middle_finger is_a: UBERON:0006050 ! digit 3 is_a: UBERON:0019232 ! manual digit 2, 3 or 4 intersection_of: UBERON:0006050 ! digit 3 intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:5003623 ! manual digit 3 plus metapodial segment property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/f/fd/Middle_finger.jpg" xsd:anyURI property_value: RO:0002173 NCBITaxon:8782 property_value: UBPROP:0000008 "This class represents the standard tetrapod configuration. Wagner proposes that avian digits I,II,III develop from C2,C3,C4. To support this scheme we have separate classes representing the avian digits (here called alula, manual digit, major digit)." xsd:string {scope="NCBITaxon:8782", seeAlso="UBERON:0012262", source="PMID:10220427", source="PhenoscapeRCN"} [Term] id: UBERON:0003624 name: manual digit 4 namespace: uberon def: "4th digit of the manus." [Wikipedia:Ring_finger] subset: pheno_slim synonym: "4th digit of hand" EXACT [] synonym: "4th finger" EXACT [] synonym: "digit 4 of fore-paw" EXACT [EMAPA:17438] synonym: "digitus annularis" RELATED LATIN [Wikipedia:Ring_finger] synonym: "finger 4" EXACT [EHDAA2:0000529] synonym: "fore digit IV" EXACT [AAO:0010642] synonym: "fore limb digit 4" EXACT [OBOL:accepted] synonym: "fourth digit of hand" EXACT [FMA:24948] synonym: "fourth finger" EXACT [] synonym: "hand digit 4" EXACT [MA:0000457] synonym: "hand digit 4" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "ring finger" NARROW [] xref: AAO:0010642 xref: EHDAA2:0000529 xref: EMAPA:17438 xref: FMA:24948 xref: MA:0000457 xref: NCIT:C52837 xref: SCTID:362768001 xref: UMLS:C0230398 {source="ncithesaurus:Hand_Digit_4"} xref: Wikipedia:Ring_finger is_a: UBERON:0006051 ! digit 4 is_a: UBERON:0019232 ! manual digit 2, 3 or 4 intersection_of: UBERON:0006051 ! digit 4 intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:5003624 ! manual digit 4 plus metapodial segment property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/1/14/Ring_finger.JPG" xsd:anyURI property_value: RO:0002173 NCBITaxon:8782 [Term] id: UBERON:0003625 name: manual digit 5 namespace: uberon def: "5th digit of the manus." [Wikipedia:Little_finger] subset: pheno_slim synonym: "5th digit of hand" EXACT [] synonym: "5th finger" EXACT [] synonym: "digit 5 of fore-paw" EXACT [EMAPA:17441] synonym: "fifth digit of hand" EXACT [FMA:24949] synonym: "fifth finger" EXACT [] synonym: "finger 5" EXACT [EHDAA2:0000535] synonym: "fore digit V" EXACT [AAO:0010643] synonym: "fore limb digit 5" EXACT [OBOL:accepted] synonym: "hand digit 5" EXACT [MA:0000458] synonym: "hand digit 5" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "little finger" NARROW [] synonym: "manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "manual digitus minimus" RELATED LATIN [Wikipedia:Little_finger] synonym: "manual digitus V" RELATED LATIN [Wikipedia:Little_finger] synonym: "manus digiti minimi" RELATED [] synonym: "manus quintus" RELATED LATIN [Wikipedia:Little_finger] xref: AAO:0010643 xref: EHDAA2:0000535 xref: EMAPA:17441 xref: FMA:24949 xref: MA:0000458 xref: NCIT:C52838 xref: SCTID:362773007 xref: UMLS:C0230403 {source="ncithesaurus:Hand_Digit_5"} xref: Wikipedia:Little_finger is_a: UBERON:0006052 ! digit 5 is_a: UBERON:0019231 ! manual digit 1 or 5 intersection_of: UBERON:0006052 ! digit 5 intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:5003625 ! manual digit 5 plus metapodial segment property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ed/Pink.jpg" xsd:anyURI [Term] id: UBERON:0003631 name: pedal digit 1 namespace: uberon def: "1st digit of the hind autopod." [Wikipedia:Hallux] subset: pheno_slim synonym: "big toe" NARROW [] synonym: "digit 1 of hind-paw" EXACT [EMAPA:17460] synonym: "digit 1 of pes" EXACT [] synonym: "digitus primus (I) pedis" RELATED [BTO:0002349] synonym: "digitus primus pedis" EXACT LATIN [] synonym: "first toe" RELATED [EMAPA:17460] synonym: "foot digit 1" EXACT [MA:0000465] synonym: "foot digit 1" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "great toe" EXACT [FMA:25047] synonym: "hallex" EXACT [] synonym: "hallux" EXACT LATIN [FMA:TA] synonym: "hallux; digitus primus [I]" EXACT [FMA:25047] synonym: "hind digit 1" EXACT [] synonym: "hind digit I" EXACT [AAO:0010644] synonym: "hind limb digit 1" EXACT [OBOL:accepted] synonym: "hindlimb dewclaw" NARROW SENSU [Wikipedia:Dewclaw] synonym: "large toe" RELATED [EMAPA:17460] synonym: "pedal digit 1" EXACT [] synonym: "pedal digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "pes digit I" EXACT [] synonym: "preaxial digit of hindlimb" EXACT [] synonym: "toe 1" EXACT [EHDAA2:0002037] xref: AAO:0010644 xref: BTO:0002349 xref: EHDAA2:0002037 xref: EMAPA:17460 xref: FMA:25047 xref: GAID:45 xref: MA:0000465 xref: MESH:D006214 xref: NCIT:C52839 xref: SCTID:21699005 xref: SCTID:302546000 xref: UMLS:C1708079 {source="ncithesaurus:Foot_Digit_1"} xref: VSAO:0000201 xref: Wikipedia:Hallux is_a: UBERON:0006048 ! digit 1 is_a: UBERON:0019241 ! pedal digit 1 or 5 intersection_of: UBERON:0006048 ! digit 1 intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:5003631 ! pedal digit 1 plus metapodial segment relationship: preaxialmost_part_of UBERON:0002387 ! pes property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ab/RightFootToes.jpg" xsd:anyURI [Term] id: UBERON:0003632 name: pedal digit 2 namespace: uberon def: "2nd digit of the hind autopod." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "2nd toe" EXACT [] synonym: "digit 2 of hind-paw" EXACT [EMAPA:17463] synonym: "digitus secundus (II) pedis" RELATED [BTO:0002350] synonym: "digitus secundus [ii]" EXACT [FMA:25048] synonym: "digitus secundus pedis" EXACT LATIN [BTO:0002350] synonym: "foot digit 2" EXACT [MA:0000466] synonym: "foot digit 2" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind digit 2" EXACT [] synonym: "hind digit II" EXACT [AAO:0010645] synonym: "hind limb digit 2" EXACT [OBOL:accepted] synonym: "pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "pes digit II" EXACT [] synonym: "second digit of foot" EXACT [FMA:25048] synonym: "second toe" EXACT [FMA:25048] synonym: "toe 2" EXACT [EHDAA2:0002042] xref: AAO:0010645 xref: BTO:0002350 xref: EHDAA2:0002042 xref: EMAPA:17463 xref: FMA:25048 xref: MA:0000466 xref: NCIT:C52840 xref: SCTID:362817008 xref: UMLS:C1708081 {source="ncithesaurus:Foot_Digit_2"} is_a: UBERON:0006049 ! digit 2 is_a: UBERON:0019242 ! pedal digit 2, 3 or 4 intersection_of: UBERON:0006049 ! digit 2 intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:5003632 ! pedal digit 2 plus metapodial segment [Term] id: UBERON:0003633 name: pedal digit 3 namespace: uberon def: "3rd digit of the hind autopod." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "3rd toe" EXACT [] synonym: "digit 3 of hind-paw" EXACT [EMAPA:17466] synonym: "digitus tertius (III) pedis" EXACT [BTO:0002351] synonym: "digitus tertius [iii]" EXACT [FMA:25051] synonym: "digitus tertius pedis" EXACT LATIN [BTO:0002351] synonym: "foot digit 3" EXACT [MA:0000467] synonym: "foot digit 3" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind digit 3" EXACT [] synonym: "hind digit III" EXACT [AAO:0010646] synonym: "hind limb digit 3" EXACT [OBOL:accepted] synonym: "pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "pes digit III" EXACT [] synonym: "third digit of foot" EXACT [FMA:25051] synonym: "third toe" EXACT [FMA:25051] synonym: "toe 3" EXACT [EHDAA2:0002047] xref: AAO:0010646 xref: BTO:0002351 xref: EHDAA2:0002047 xref: EMAPA:17466 xref: FMA:25051 xref: MA:0000467 xref: NCIT:C52841 xref: SCTID:362821001 xref: UMLS:C1708083 {source="ncithesaurus:Foot_Digit_3"} is_a: UBERON:0006050 ! digit 3 is_a: UBERON:0019242 ! pedal digit 2, 3 or 4 intersection_of: UBERON:0006050 ! digit 3 intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:5003633 ! pedal digit 3 plus metapodial segment [Term] id: UBERON:0003634 name: pedal digit 4 namespace: uberon def: "4th digit of the hind autopod." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "4th toe" EXACT [] synonym: "digit 4 of hind-paw" EXACT [EMAPA:17469] synonym: "digitus quartis pedis" EXACT LATIN [BTO:0002352] synonym: "digitus quartus (IV) pedis" RELATED [BTO:0002352] synonym: "digitus quartus [iv]" EXACT [FMA:25052] synonym: "foot digit 4" EXACT [MA:0000468] synonym: "foot digit 4" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fourth digit of foot" EXACT [FMA:25052] synonym: "fourth toe" EXACT [FMA:25052] synonym: "hind digit 4" EXACT [] synonym: "hind digit IV" EXACT [AAO:0010656] synonym: "hind limb digit 4" EXACT [OBOL:accepted] synonym: "pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "pes digit IV" EXACT [] synonym: "toe 4" EXACT [EHDAA2:0002052] xref: AAO:0010656 xref: BTO:0002352 xref: EHDAA2:0002052 xref: EMAPA:17469 xref: FMA:25052 xref: MA:0000468 xref: NCIT:C52842 xref: SCTID:362826006 xref: UMLS:C1708085 {source="ncithesaurus:Foot_Digit_4"} is_a: UBERON:0006051 ! digit 4 is_a: UBERON:0019242 ! pedal digit 2, 3 or 4 relationship: part_of UBERON:5003634 ! pedal digit 4 plus metapodial segment [Term] id: UBERON:0003635 name: pedal digit 5 namespace: uberon def: "5th digit of the hind autopod." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Fifth_toe] subset: pheno_slim synonym: "5th toe" EXACT [] synonym: "digit 5 of hind-paw" EXACT [EMAPA:17472] synonym: "digitus minimus pedis" EXACT LATIN [Wikipedia:Fifth_toe] synonym: "digitus minimus; digitus quintus [v]" EXACT [FMA:25053] synonym: "digitus quintus (V) pedis" RELATED [BTO:0002353] synonym: "digitus quintus [V]" EXACT [FMA:25053] synonym: "digitus quintus [V] pedis" EXACT LATIN [FMA:25053, FMA:TA] synonym: "digitus quintus of pes" EXACT [] synonym: "digitus quintus pedis" EXACT LATIN [Wikipedia:Fifth_toe] synonym: "digitus V of pes" EXACT [] synonym: "fifth digit of foot" EXACT [FMA:25053] synonym: "fifth toe" EXACT [FMA:25053] synonym: "foot digit 5" EXACT [MA:0000469] synonym: "foot digit 5" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind digit 5" EXACT [] synonym: "hind digit V" EXACT [AAO:0010658] synonym: "hind limb digit 5" EXACT [OBOL:accepted] synonym: "little toe" NARROW [] synonym: "pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "pedal digitus minimus" EXACT [] synonym: "pes digit V" EXACT [] synonym: "toe 5" EXACT [EHDAA2:0002057] xref: AAO:0010658 xref: BTO:0002353 xref: EHDAA2:0002057 xref: EMAPA:17472 xref: FMA:25053 xref: MA:0000469 xref: NCIT:C52843 xref: SCTID:362830009 xref: UMLS:C1708087 {source="ncithesaurus:Foot_Digit_5"} xref: Wikipedia:Fifth_toe is_a: UBERON:0006052 ! digit 5 is_a: UBERON:0019241 ! pedal digit 1 or 5 intersection_of: UBERON:0006052 ! digit 5 intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:5003635 ! pedal digit 5 plus metapodial segment property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/52/Gray291.png" xsd:anyURI [Term] id: UBERON:0003636 name: manual digit 2 phalanx namespace: uberon def: "A phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "2 nd digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "2 nd digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "2 nd digit of hand phalanx" EXACT [OBOL:automatic] synonym: "2 nd finger digit long bone" EXACT [OBOL:automatic] synonym: "2 nd finger long bone of digit" EXACT [OBOL:automatic] synonym: "2 nd finger phalanx" EXACT [OBOL:automatic] synonym: "digit long bone of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 2 nd finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 2" EXACT [OBOL:automatic] synonym: "digit long bone of second finger" EXACT [OBOL:automatic] synonym: "fore limb digit 2 phalanx" EXACT [OBOL:accepted] synonym: "hand digit 2 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 2 long bone of digit" EXACT [OBOL:automatic] synonym: "hand digit 2 phalanx" EXACT [MA:0001390] synonym: "hand digit 2 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "index finger phalanx" EXACT [FMA:35480] synonym: "long bone of digit of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 2 nd finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 2" EXACT [OBOL:automatic] synonym: "long bone of digit of second finger" EXACT [OBOL:automatic] synonym: "manual digit II phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 2 nd finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 2" EXACT [OBOL:automatic] synonym: "phalanx of index finger" EXACT [FMA:35480] synonym: "phalanx of manual digit 2" EXACT [OBOL:accepted] synonym: "phalanx of second finger" EXACT [OBOL:automatic] synonym: "second finger digit long bone" EXACT [OBOL:automatic] synonym: "second finger long bone of digit" EXACT [OBOL:automatic] synonym: "second finger phalanx" EXACT [OBOL:automatic] xref: EMAPA:19115 xref: FMA:35480 xref: MA:0001390 xref: NCIT:C52776 xref: SCTID:361783009 xref: UMLS:C1708312 {source="ncithesaurus:Hand_Digit_2_Phalanx"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0015026 ! manual digit 2 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: develops_from UBERON:0010676 ! manual digit 2 phalanx cartilage element [Term] id: UBERON:0003637 name: manual digit 3 phalanx namespace: uberon def: "A phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "3 rd digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "3 rd digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "3 rd digit of hand phalanx" EXACT [OBOL:automatic] synonym: "3 rd finger digit long bone" EXACT [OBOL:automatic] synonym: "3 rd finger long bone of digit" EXACT [OBOL:automatic] synonym: "3 rd finger phalanx" EXACT [OBOL:automatic] synonym: "digit long bone of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 3 rd finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 3" EXACT [OBOL:automatic] synonym: "digit long bone of third finger" EXACT [OBOL:automatic] synonym: "fore limb digit 3 phalanx" EXACT [OBOL:accepted] synonym: "hand digit 3 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 3 long bone of digit" EXACT [OBOL:automatic] synonym: "hand digit 3 phalanx" EXACT [MA:0001391] synonym: "hand digit 3 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "long bone of digit of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 3 rd finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 3" EXACT [OBOL:automatic] synonym: "long bone of digit of third finger" EXACT [OBOL:automatic] synonym: "manual digit III phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle finger phalanx" EXACT [FMA:35483] synonym: "phalanx of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 3 rd finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 3" EXACT [OBOL:automatic] synonym: "phalanx of middle finger" EXACT [FMA:35483] synonym: "phalanx of third finger" EXACT [OBOL:automatic] synonym: "third finger digit long bone" EXACT [OBOL:automatic] synonym: "third finger long bone of digit" EXACT [OBOL:automatic] synonym: "third finger phalanx" EXACT [OBOL:automatic] xref: EMAPA:19117 xref: FMA:35483 xref: MA:0001391 xref: NCIT:C52775 xref: SCTID:361785002 xref: UMLS:C1708314 {source="ncithesaurus:Hand_Digit_3_Phalanx"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0015027 ! manual digit 3 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: develops_from UBERON:0010677 ! manual digit 3 phalanx cartilage element [Term] id: UBERON:0003638 name: manual digit 4 phalanx namespace: uberon def: "A phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "4 th digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "4 th digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "4 th digit of hand phalanx" EXACT [OBOL:automatic] synonym: "4 th finger digit long bone" EXACT [OBOL:automatic] synonym: "4 th finger long bone of digit" EXACT [OBOL:automatic] synonym: "4 th finger phalanx" EXACT [OBOL:automatic] synonym: "digit long bone of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 4 th finger" EXACT [OBOL:automatic] synonym: "digit long bone of fourth finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 4" EXACT [OBOL:automatic] synonym: "fore limb digit 4 phalanx" EXACT [OBOL:accepted] synonym: "fourth finger digit long bone" EXACT [OBOL:automatic] synonym: "fourth finger long bone of digit" EXACT [OBOL:automatic] synonym: "fourth finger phalanx" EXACT [OBOL:automatic] synonym: "hand digit 4 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 4 long bone of digit" EXACT [OBOL:automatic] synonym: "hand digit 4 phalanx" EXACT [MA:0001392] synonym: "hand digit 4 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "long bone of digit of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 4 th finger" EXACT [OBOL:automatic] synonym: "long bone of digit of fourth finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 4" EXACT [OBOL:automatic] synonym: "manual digit IV phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 4 th finger" EXACT [OBOL:automatic] synonym: "phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 4" EXACT [OBOL:automatic] synonym: "phalanx of ring finger" EXACT [FMA:35486] synonym: "ring finger phalanx" EXACT [FMA:35486] xref: EMAPA:19119 xref: FMA:35486 xref: MA:0001392 xref: NCIT:C52774 xref: SCTID:361787005 xref: UMLS:C1708316 {source="ncithesaurus:Hand_Digit_4_Phalanx"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0015028 ! manual digit 4 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: develops_from UBERON:0010678 ! manual digit 4 phalanx cartilage element [Term] id: UBERON:0003639 name: manual digit 5 phalanx namespace: uberon def: "A phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "5 th digit of hand digit long bone" EXACT [OBOL:automatic] synonym: "5 th digit of hand long bone of digit" EXACT [OBOL:automatic] synonym: "5 th digit of hand phalanx" EXACT [OBOL:automatic] synonym: "5 th finger digit long bone" EXACT [OBOL:automatic] synonym: "5 th finger long bone of digit" EXACT [OBOL:automatic] synonym: "5 th finger phalanx" EXACT [OBOL:automatic] synonym: "digit long bone of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "digit long bone of 5 th finger" EXACT [OBOL:automatic] synonym: "digit long bone of fifth finger" EXACT [OBOL:automatic] synonym: "digit long bone of hand digit 5" EXACT [OBOL:automatic] synonym: "fifth finger digit long bone" EXACT [OBOL:automatic] synonym: "fifth finger long bone of digit" EXACT [OBOL:automatic] synonym: "fifth finger phalanx" EXACT [OBOL:automatic] synonym: "fore limb digit 5 phalanx" EXACT [OBOL:accepted] synonym: "hand digit 5 digit long bone" EXACT [OBOL:automatic] synonym: "hand digit 5 long bone of digit" EXACT [OBOL:automatic] synonym: "hand digit 5 phalanx" EXACT [MA:0001393] synonym: "hand digit 5 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "little finger phalanx" EXACT [FMA:35489] synonym: "long bone of digit of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "long bone of digit of 5 th finger" EXACT [OBOL:automatic] synonym: "long bone of digit of fifth finger" EXACT [OBOL:automatic] synonym: "long bone of digit of hand digit 5" EXACT [OBOL:automatic] synonym: "manual digit V phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "phalanx of 5 th finger" EXACT [OBOL:automatic] synonym: "phalanx of 5th finger" EXACT [] synonym: "phalanx of fifth digit of hand" EXACT [FMA:35489] synonym: "phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "phalanx of hand digit 5" EXACT [OBOL:automatic] synonym: "phalanx of little finger" EXACT [FMA:35489] synonym: "phalanx of manual digitus minimus" EXACT [OBOL:automatic] xref: EMAPA:19121 xref: FMA:35489 xref: MA:0001393 xref: NCIT:C52773 xref: SCTID:361789008 xref: UMLS:C1708317 {source="ncithesaurus:Hand_Digit_5_Phalanx"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0015029 ! manual digit 5 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: develops_from UBERON:0010679 ! manual digit 5 phalanx cartilage element [Term] id: UBERON:0003640 name: pedal digit 1 phalanx namespace: uberon def: "A phalanx that is part of a foot digit 1 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "big toe phalanx" EXACT [FMA:32884] synonym: "digit long bone of foot digit 1" EXACT [OBOL:automatic] synonym: "digit long bone of hallux" EXACT [OBOL:automatic] synonym: "foot digit 1 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 1 long bone of digit" EXACT [OBOL:automatic] synonym: "foot digit 1 phalanx" EXACT [MA:0001381] synonym: "foot digit 1 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hallux digit long bone" EXACT [OBOL:automatic] synonym: "hallux long bone of digit" EXACT [OBOL:automatic] synonym: "hallux phalanx" EXACT [OBOL:automatic] synonym: "hind limb digit 1 phalanx" EXACT [OBOL:accepted] synonym: "long bone of digit of foot digit 1" EXACT [OBOL:automatic] synonym: "long bone of digit of hallux" EXACT [OBOL:automatic] synonym: "pedal digit I phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of big toe" EXACT [FMA:32884] synonym: "phalanx of first digit of foot" EXACT [FMA:32884] synonym: "phalanx of first toe" RELATED [FMA:32884] synonym: "phalanx of foot digit 1" EXACT [OBOL:automatic] synonym: "phalanx of great toe" EXACT [FMA:32884] synonym: "phalanx of hallux" EXACT [OBOL:automatic] xref: EMAPA:19124 xref: FMA:32884 xref: MA:0001381 xref: NCIT:C52778 xref: SCTID:361798006 xref: UMLS:C1708080 {source="ncithesaurus:Foot_Digit_1_Phalanx"} is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0015031 ! pedal digit 1 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: develops_from UBERON:0010680 ! pedal digit 1 phalanx cartilage element [Term] id: UBERON:0003641 name: pedal digit 2 phalanx namespace: uberon def: "A phalanx that is part of a foot digit 2 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "digit long bone of foot digit 2" EXACT [OBOL:automatic] synonym: "foot digit 2 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 2 long bone of digit" EXACT [OBOL:automatic] synonym: "foot digit 2 phalanx" EXACT [MA:0001382] synonym: "foot digit 2 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 phalanx" EXACT [OBOL:accepted] synonym: "long bone of digit of foot digit 2" EXACT [OBOL:automatic] synonym: "pedal digit II phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "phalanx of second toe" EXACT [FMA:32899] synonym: "second toe phalanx" EXACT [FMA:32899] xref: EMAPA:19126 xref: FMA:32899 xref: MA:0001382 xref: NCIT:C52779 xref: SCTID:361800004 xref: UMLS:C1708082 {source="ncithesaurus:Foot_Digit_2_Phalanx"} is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0015032 ! pedal digit 2 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: develops_from UBERON:0010681 ! pedal digit 2 phalanx cartilage element [Term] id: UBERON:0003642 name: pedal digit 3 phalanx namespace: uberon def: "A phalanx that is part of a foot digit 3 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "digit long bone of foot digit 3" EXACT [OBOL:automatic] synonym: "foot digit 3 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 3 long bone of digit" EXACT [OBOL:automatic] synonym: "foot digit 3 phalanx" EXACT [MA:0001383] synonym: "foot digit 3 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 phalanx" EXACT [OBOL:accepted] synonym: "long bone of digit of foot digit 3" EXACT [OBOL:automatic] synonym: "pedal digit III phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "phalanx of third toe" EXACT [FMA:32900] synonym: "third toe phalanx" EXACT [FMA:32900] xref: EMAPA:19128 xref: FMA:32900 xref: MA:0001383 xref: NCIT:C52780 xref: SCTID:361802007 xref: UMLS:C1708084 {source="ncithesaurus:Foot_Digit_3_Phalanx"} is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0015033 ! pedal digit 3 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: develops_from UBERON:0010682 ! pedal digit 3 phalanx cartilage element [Term] id: UBERON:0003643 name: respiratory system arterial blood vessel namespace: uberon def: "An arterial blood vessel that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37565 {source="MA:th"} xref: MA:0001800 is_a: UBERON:0003504 ! respiratory system blood vessel is_a: UBERON:0003509 ! arterial blood vessel intersection_of: UBERON:0003509 ! arterial blood vessel intersection_of: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003644 name: kidney arterial blood vessel namespace: uberon def: "An arterial blood vessel that is part of a kidney [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "kidney arterial system" RELATED [EMAPA:31436] xref: EMAPA:31436 xref: MA:0002578 is_a: UBERON:0003509 ! arterial blood vessel is_a: UBERON:0003517 ! kidney blood vessel intersection_of: UBERON:0003509 ! arterial blood vessel intersection_of: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0003645 name: metacarpal bone of digit 1 namespace: uberon def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 1." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "finger 1 metacarpus" EXACT [] synonym: "first digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "first digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "first metacarpal bone" EXACT [FMA:23899] synonym: "forelimb digit 1 metacarpus" RELATED [EMAPA:19112] synonym: "hand digit 1 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 1 metacarpal bone" EXACT [OBOL:automatic] synonym: "manual digit 1 metacarpus" EXACT [] synonym: "metacarpal 1" EXACT [] synonym: "metacarpal bone digit 1" EXACT [MA:0001364] synonym: "metacarpal bone of digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal bone of first digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 1" EXACT [OBOL:automatic] synonym: "metacarpal bone of thumb" EXACT [OBOL:automatic] synonym: "metacarpal I" EXACT [FMA:23899] synonym: "metacarpal of first digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 1" EXACT [OBOL:automatic] synonym: "metacarpal of thumb" EXACT [OBOL:automatic] synonym: "thumb metacarpal" EXACT [OBOL:automatic] synonym: "thumb metacarpal bone" EXACT [OBOL:automatic] xref: AAO:0010616 xref: EMAPA:19112 xref: FMA:23899 xref: MA:0001364 xref: NCIT:C52796 xref: SCTID:181973009 xref: UMLS:C1708987 {source="ncithesaurus:Metacarpal_Bone_Digit_1"} is_a: UBERON:0002374 ! metacarpal bone is_a: UBERON:0013581 ! metapodium bone 1 is_a: UBERON:0015043 ! manual digit 1 metacarpus endochondral element intersection_of: UBERON:0015043 ! manual digit 1 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010570 ! manual digit 1 metacarpus cartilage element property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The first metacarpal bone or the metacarpal bone of the thumb is the first bone of the thumb. It is connected to the trapezium of the carpus at the first carpometacarpal joint and to the proximal thumb phalanx at the first metacarpophalangeal joint[Wikipedia:First_metacarpal_bone]." xsd:string {source="Wikipedia:First_metacarpal_bone"} property_value: UBPROP:0000104 "1" xsd:nonNegativeInteger [Term] id: UBERON:0003646 name: metacarpal bone of digit 2 namespace: uberon def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 2." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "2 nd digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "2 nd digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "2 nd finger metacarpal" EXACT [OBOL:automatic] synonym: "2 nd finger metacarpal bone" EXACT [OBOL:automatic] synonym: "finger 2 metacarpus" EXACT [] synonym: "forelimb digit 2 metacarpus" RELATED [EMAPA:19114] synonym: "hand digit 2 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 2 metacarpal bone" EXACT [OBOL:automatic] synonym: "manual digit 2 metacarpus" EXACT [] synonym: "metacarpal 2" EXACT [] synonym: "metacarpal bone digit 2" EXACT [MA:0001365] synonym: "metacarpal bone of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 2 nd finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal bone of hand digit 2" EXACT [OBOL:automatic] synonym: "metacarpal bone of second finger" EXACT [OBOL:automatic] synonym: "metacarpal II" EXACT [FMA:23900] synonym: "metacarpal of 2 nd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 2 nd finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 2" EXACT [OBOL:automatic] synonym: "metacarpal of second finger" EXACT [OBOL:automatic] synonym: "second finger metacarpal" EXACT [OBOL:automatic] synonym: "second finger metacarpal bone" EXACT [OBOL:automatic] synonym: "second metacarpal bone" EXACT [FMA:23900] xref: AAO:0000853 xref: EMAPA:19114 xref: FMA:23900 xref: MA:0001365 xref: NCIT:C52795 xref: SCTID:263399007 xref: UMLS:C1708988 {source="ncithesaurus:Metacarpal_Bone_Digit_2"} is_a: UBERON:0002374 ! metacarpal bone is_a: UBERON:0013582 ! metapodium bone 2 is_a: UBERON:0015044 ! manual digit 2 metacarpus endochondral element intersection_of: UBERON:0015044 ! manual digit 2 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010571 ! manual digit 2 metacarpus cartilage element property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with the prepollex and carpal 2(1) or carpal 2+3(1+2) proximally and with the proximal phalanx of digit II(I) distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000853", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000104 "2" xsd:nonNegativeInteger [Term] id: UBERON:0003647 name: metacarpal bone of digit 3 namespace: uberon def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 3[Automatically generated definition]." [OBOL:automatic, Wikipedia:Third_metacarpal_bone] subset: human_reference_atlas subset: pheno_slim synonym: "3 rd digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "3 rd digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "3 rd finger metacarpal" EXACT [OBOL:automatic] synonym: "3 rd finger metacarpal bone" EXACT [OBOL:automatic] synonym: "finger 3 metacarpus" EXACT [] synonym: "forelimb cannon bone" NARROW SENSU [https://orcid.org/0000-0002-6601-2165] synonym: "forelimb digit 3 metacarpus" RELATED [EMAPA:19116] synonym: "hand digit 3 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 3 metacarpal bone" EXACT [OBOL:automatic] synonym: "manual digit 3 metacarpus" EXACT [] synonym: "metacarpal 3" EXACT [] synonym: "metacarpal bone digit 3" EXACT [MA:0001366] synonym: "metacarpal bone of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 3 rd finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal bone of hand digit 3" EXACT [OBOL:automatic] synonym: "metacarpal bone of third finger" EXACT [OBOL:automatic] synonym: "metacarpal III" EXACT [FMA:23901] synonym: "metacarpal of 3 rd digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 3 rd finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 3" EXACT [OBOL:automatic] synonym: "metacarpal of third finger" EXACT [OBOL:automatic] synonym: "third finger metacarpal" EXACT [OBOL:automatic] synonym: "third finger metacarpal bone" EXACT [OBOL:automatic] synonym: "third metacarpal bone" EXACT [FMA:23901] xref: AAO:0000854 xref: EMAPA:19116 xref: FMA:23901 xref: MA:0001366 xref: NCIT:C52794 xref: SCTID:263400000 xref: UMLS:C1708989 {source="ncithesaurus:Metacarpal_Bone_Digit_3"} xref: Wikipedia:Third_metacarpal_bone is_a: UBERON:0002374 ! metacarpal bone is_a: UBERON:0013583 ! metapodium bone 3 is_a: UBERON:0015045 ! manual digit 3 metacarpus endochondral element intersection_of: UBERON:0015045 ! manual digit 3 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010572 ! manual digit 3 metacarpus cartilage element property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with carpal 3(2) proximally and with the proximal phalanx of digit III(II) distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000854", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The third metacarpal bone (metacarpal bone of the middle finger) is a little smaller than the second. The dorsal aspect of its base presents on its radial side a pyramidal eminence, the styloid process, which extends upward behind the capitate; immediately distal to this is a rough surface for the attachment of the extensor carpi radialis brevis muscle. The carpal articular facet is concave behind, flat in front, and articulates with the capitate. On the radial side is a smooth, concave facet for articulation with the second metacarpal, and on the ulnar side two small oval facets for the fourth metacarpal[Wikipedia:Third_metacarpal_bone]." xsd:string {source="Wikipedia:Third_metacarpal_bone"} property_value: UBPROP:0000104 "3" xsd:nonNegativeInteger [Term] id: UBERON:0003648 name: metacarpal bone of digit 4 namespace: uberon def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 4." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "4 th digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "4 th digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "4 th finger metacarpal" EXACT [OBOL:automatic] synonym: "4 th finger metacarpal bone" EXACT [OBOL:automatic] synonym: "finger 4 metacarpus" EXACT [] synonym: "forelimb digit 4 metacarpus" RELATED [EMAPA:19118] synonym: "fourth finger metacarpal" EXACT [OBOL:automatic] synonym: "fourth finger metacarpal bone" EXACT [OBOL:automatic] synonym: "fourth metacarpal bone" EXACT [FMA:23902] synonym: "hand digit 4 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 4 metacarpal bone" EXACT [OBOL:automatic] synonym: "manual digit 4 metacarpus" EXACT [] synonym: "metacarpal 4" EXACT [] synonym: "metacarpal bone digit 4" EXACT [MA:0001367] synonym: "metacarpal bone of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 4 th finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal bone of fourth finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 4" EXACT [OBOL:automatic] synonym: "metacarpal IV" EXACT [FMA:23902] synonym: "metacarpal of 4 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 4 th finger" EXACT [OBOL:automatic] synonym: "metacarpal of fourth finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 4" EXACT [OBOL:automatic] xref: AAO:0010615 xref: EMAPA:19118 xref: FMA:23902 xref: MA:0001367 xref: NCIT:C52793 xref: SCTID:263401001 xref: UMLS:C1708990 {source="ncithesaurus:Metacarpal_Bone_Digit_4"} is_a: UBERON:0002374 ! metacarpal bone is_a: UBERON:0013584 ! metapodium bone 4 is_a: UBERON:0015046 ! manual digit 4 metacarpus endochondral element intersection_of: UBERON:0015046 ! manual digit 4 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010573 ! manual digit 4 metacarpus cartilage element property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The fourth metacarpal bone (metacarpal bone of the ring finger) is shorter and smaller than the third. The base is small and quadrilateral; its superior surface presents two facets, a large one medially for articulation with the hamate, and a small one laterally for the capitate. On the radial side are two oval facets, for articulation with the third metacarpal; and on the ulnar side a single concave facet, for the fifth metacarpal[Wikipedia:Fourth_metacarpal_bone]." xsd:string {source="Wikipedia:Fourth_metacarpal_bone"} property_value: UBPROP:0000104 "4" xsd:nonNegativeInteger [Term] id: UBERON:0003649 name: metacarpal bone of digit 5 namespace: uberon def: "A metacarpal bone that distally_connected_to a proximal phalanx of manual digit 5." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "5 th digit of hand metacarpal" EXACT [OBOL:automatic] synonym: "5 th digit of hand metacarpal bone" EXACT [OBOL:automatic] synonym: "5 th finger metacarpal" EXACT [OBOL:automatic] synonym: "5 th finger metacarpal bone" EXACT [OBOL:automatic] synonym: "fifth finger metacarpal" EXACT [OBOL:automatic] synonym: "fifth finger metacarpal bone" EXACT [OBOL:automatic] synonym: "fifth metacarpal bone" EXACT [FMA:23903] synonym: "finger 5 metacarpus" EXACT [] synonym: "forelimb digit 5 metacarpus" RELATED [EMAPA:19120] synonym: "hand digit 5 metacarpal" EXACT [OBOL:automatic] synonym: "hand digit 5 metacarpal bone" EXACT [OBOL:automatic] synonym: "manual digit 5 metacarpus" EXACT [] synonym: "metacarpal 5" EXACT [] synonym: "metacarpal bone digit 5" EXACT [MA:0001368] synonym: "metacarpal bone of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal bone of 5 th finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal bone of fifth finger" EXACT [OBOL:automatic] synonym: "metacarpal bone of hand digit 5" EXACT [OBOL:automatic] synonym: "metacarpal of 5 th digit of hand" EXACT [OBOL:automatic] synonym: "metacarpal of 5 th finger" EXACT [OBOL:automatic] synonym: "metacarpal of fifth finger" EXACT [OBOL:automatic] synonym: "metacarpal of hand digit 5" EXACT [OBOL:automatic] synonym: "metacarpal V" EXACT [] xref: AAO:0000855 xref: EMAPA:19120 xref: FMA:23903 xref: MA:0001368 xref: NCIT:C52792 xref: SCTID:263402008 xref: UMLS:C1711224 {source="ncithesaurus:Metacarpal_Bone_Digit_5"} is_a: UBERON:0002374 ! metacarpal bone is_a: UBERON:0013585 ! metapodium bone 5 is_a: UBERON:0015047 ! manual digit 5 metacarpus endochondral element intersection_of: UBERON:0015047 ! manual digit 5 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010574 ! manual digit 5 metacarpus cartilage element property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell shaped bones of endochondral origin with cartilaginous epiphyses that articulates with carpal 5(4) proximally and with the proximal phalanx of digit V(IV) distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000855", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The fifth metacarpal bone (metacarpal bone of the little finger or pinky finger) is the most lateral metacarpal[Wikipedia:Fifth_metacarpal_bone]." xsd:string {source="Wikipedia:Fifth_metacarpal_bone"} property_value: UBPROP:0000012 "FMA also has FMA:36782 ! Bone of fifth metacarpal bone" xsd:string {external_ontology="FMA"} property_value: UBPROP:0000104 "5" xsd:nonNegativeInteger [Term] id: UBERON:0003650 name: metatarsal bone of digit 1 namespace: uberon def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 1." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "first metatarsal bone" EXACT [FMA:24502] synonym: "foot digit 1 metatarsal bone" EXACT [OBOL:automatic] synonym: "hallux metatarsal bone" EXACT [OBOL:automatic] synonym: "hindlimb digit 1 metatarsus" RELATED [EMAPA:19123] synonym: "metatarsal 1" EXACT [] synonym: "metatarsal bone digit 1" EXACT [MA:0001369] synonym: "metatarsal bone of digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metatarsal bone of foot digit 1" EXACT [OBOL:automatic] synonym: "metatarsal bone of hallux" EXACT [OBOL:automatic] synonym: "metatarsal I" EXACT [AAO:0000925] synonym: "toe 1 metatarsal" EXACT [] synonym: "toe 1 metatarsus" EXACT [] xref: AAO:0000925 xref: EMAPA:19123 xref: FMA:24502 xref: MA:0001369 xref: NCIT:C52791 xref: SCTID:182121005 xref: UMLS:C1708999 {source="ncithesaurus:Metatarsal_Bone_Digit_1"} is_a: UBERON:0001448 ! metatarsal bone is_a: UBERON:0013581 ! metapodium bone 1 is_a: UBERON:0015037 ! pedal digit 1 metatarsal endochondral element intersection_of: UBERON:0015037 ! pedal digit 1 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010557 ! pedal digit 1 metatarsal cartilage element relationship: distally_connected_to UBERON:0004332 ! proximal phalanx of pedal digit 1 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with the prepollex and tarsal 1 proximally and with the proximal phalanx of digit I distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000925", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The first metatarsal bone is the bone in the body of the foot just behind the big toe. It is remarkable for its great thickness, and is the shortest of the metatarsal bones. The body is strong, and of well-marked prismoid form. The base presents, as a rule, no articular facets on its sides, but occasionally on the lateral side there is an oval facet, by which it articulates with the second metatarsal. Its proximal articular surface is of large size and kidney-shaped; its circumference is grooved, for the tarsometatarsal ligaments, and medially gives insertion to part of the tendon of the Tibialis anterior; its plantar angle presents a rough oval prominence for the insertion of the tendon of the Peronæus longus. The head is large; on its plantar surface are two grooved facets, on which glide sesamoid bones; the facets are separated by a smooth elevation[Wikipedia:First_metatarsal_bone]." xsd:string {source="Wikipedia:First_metatarsal_bone"} property_value: UBPROP:0000104 "1" xsd:nonNegativeInteger [Term] id: UBERON:0003651 name: metatarsal bone of digit 2 namespace: uberon def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 2." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "foot digit 2 metatarsal bone" EXACT [OBOL:automatic] synonym: "hindlimb digit 2 metatarsus" RELATED [EMAPA:19125] synonym: "metatarsal 2" EXACT [] synonym: "metatarsal bone digit 2" EXACT [MA:0001370] synonym: "metatarsal bone of digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metatarsal bone of foot digit 2" EXACT [OBOL:automatic] synonym: "metatarsal II" EXACT [AAO:0000926] synonym: "second metatarsal bone" EXACT [FMA:24503] synonym: "toe 2 metatarsal" EXACT [] synonym: "toe 2 metatarsus" EXACT [] xref: AAO:0000926 xref: EMAPA:19125 xref: FMA:24503 xref: MA:0001370 xref: NCIT:C52790 xref: SCTID:182128004 xref: UMLS:C1709000 {source="ncithesaurus:Metatarsal_Bone_Digit_2"} is_a: UBERON:0001448 ! metatarsal bone is_a: UBERON:0013582 ! metapodium bone 2 is_a: UBERON:0015038 ! pedal digit 2 metatarsal endochondral element intersection_of: UBERON:0015038 ! pedal digit 2 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010558 ! pedal digit 2 metatarsal cartilage element relationship: distally_connected_to UBERON:0004333 ! proximal phalanx of pedal digit 2 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 2 proximally and with the proximal phalanx of digit II distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000926", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000104 "2" xsd:nonNegativeInteger [Term] id: UBERON:0003652 name: metatarsal bone of digit 3 namespace: uberon def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 3[Automatically generated definition]." [OBOL:automatic, Wikipedia:Third_metatarsal_bone] subset: human_reference_atlas subset: pheno_slim synonym: "foot digit 3 metatarsal bone" EXACT [OBOL:automatic] synonym: "hindlimb cannon bone" NARROW SENSU [https://orcid.org/0000-0002-6601-2165] synonym: "hindlimb digit 3 metatarsal" RELATED [EMAPA:19127] synonym: "metatarsal 3" EXACT [] synonym: "metatarsal bone digit 3" EXACT [MA:0001371] synonym: "metatarsal bone of digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metatarsal bone of foot digit 3" EXACT [OBOL:automatic] synonym: "metatarsal III" EXACT [AAO:0000927] synonym: "third metatarsal bone" EXACT [FMA:24504] synonym: "toe 3 metatarsal" EXACT [] synonym: "toe 3 metatarsus" EXACT [] xref: AAO:0000927 xref: EMAPA:19127 xref: FMA:24504 xref: MA:0001371 xref: NCIT:C52789 xref: SCTID:182134006 xref: UMLS:C1709001 {source="ncithesaurus:Metatarsal_Bone_Digit_3"} xref: Wikipedia:Third_metatarsal_bone is_a: UBERON:0001448 ! metatarsal bone is_a: UBERON:0013583 ! metapodium bone 3 is_a: UBERON:0015039 ! pedal digit 3 metatarsal endochondral element intersection_of: UBERON:0015039 ! pedal digit 3 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010559 ! pedal digit 3 metatarsal cartilage element relationship: distally_connected_to UBERON:0004334 ! proximal phalanx of pedal digit 3 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 3 proximally and with the proximal phalanx of digit III distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000927", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The third metatarsal bone articulates proximally, by means of a triangular smooth surface, with the third cuneiform; medially, by two facets, with the second metatarsal; and laterally, by a single facet, with the fourth metatarsal. This last facet is situated at the dorsal angle of the base[Wikipedia:Third_metatarsal_bone]." xsd:string {source="Wikipedia:Third_metatarsal_bone"} property_value: UBPROP:0000104 "3" xsd:nonNegativeInteger [Term] id: UBERON:0003653 name: metatarsal bone of digit 4 namespace: uberon def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 4." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "foot digit 4 metatarsal bone" EXACT [OBOL:automatic] synonym: "fourth metatarsal bone" EXACT [FMA:24505] synonym: "hindlimb digit 4 metatarsus" RELATED [EMAPA:19129] synonym: "metatarsal 4" EXACT [] synonym: "metatarsal bone digit 4" EXACT [MA:0001372] synonym: "metatarsal bone of digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metatarsal bone of foot digit 4" EXACT [OBOL:automatic] synonym: "metatarsal IV" EXACT [AAO:0000928] synonym: "toe 4 metatarsal" EXACT [] synonym: "toe 4 metatarsus" EXACT [] xref: AAO:0000928 xref: EMAPA:19129 xref: FMA:24505 xref: MA:0001372 xref: NCIT:C52788 xref: SCTID:182139001 xref: UMLS:C1709002 {source="ncithesaurus:Metatarsal_Bone_Digit_4"} is_a: UBERON:0001448 ! metatarsal bone is_a: UBERON:0013584 ! metapodium bone 4 is_a: UBERON:0015040 ! pedal digit 4 metatarsal endochondral element intersection_of: UBERON:0015040 ! pedal digit 4 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010560 ! pedal digit 4 metatarsal cartilage element relationship: distally_connected_to UBERON:0004335 ! proximal phalanx of pedal digit 4 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 4 or the distal head of the tibiale-fibulare proximally and with the proximal phalanx of digit IV distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000928", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The fourth metatarsal bone is smaller in size than the third; its base presents an oblique quadrilateral surface for articulation with the cuboid; a smooth facet on the medial side, divided by a ridge into an anterior portion for articulation with the third metatarsal, and a posterior portion for articulation with the third cuneiform; on the lateral side a single facet, for articulation with the fifth metatarsal[Wikipedia:Fourth_metatarsal_bone]." xsd:string {source="Wikipedia:Fourth_metatarsal_bone"} property_value: UBPROP:0000104 "4" xsd:nonNegativeInteger [Term] id: UBERON:0003654 name: metatarsal bone of digit 5 namespace: uberon def: "A metatarsal bone that distally_connected_to a proximal phalanx of pedal digit 5." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "fifth metatarsal bone" EXACT [FMA:24506] synonym: "foot digit 5 metatarsal bone" EXACT [OBOL:automatic] synonym: "hindlimb digit 5 metatarsus" RELATED [EMAPA:19131] synonym: "metatarsal 5" EXACT [] synonym: "metatarsal bone digit 5" EXACT [MA:0001373] synonym: "metatarsal bone of digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metatarsal bone of foot digit 5" EXACT [OBOL:automatic] synonym: "metatarsal V" EXACT [AAO:0000929] synonym: "toe 5 metatarsal" EXACT [] synonym: "toe 5 metatarsus" EXACT [] xref: AAO:0000929 xref: EMAPA:19131 xref: FMA:24506 xref: MA:0001373 xref: NCIT:C52787 xref: SCTID:182144008 xref: UMLS:C1709003 {source="ncithesaurus:Metatarsal_Bone_Digit_5"} is_a: UBERON:0001448 ! metatarsal bone is_a: UBERON:0013585 ! metapodium bone 5 is_a: UBERON:0015041 ! pedal digit 5 metatarsal endochondral element intersection_of: UBERON:0015041 ! pedal digit 5 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010561 ! pedal digit 5 metatarsal cartilage element relationship: distally_connected_to UBERON:0004336 ! proximal phalanx of pedal digit 5 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Dumb-bell-shaped bone of endochondral origin with cartilaginous epiphyses that articulates with tarsal 5 or the distal head of the tibiale-fibulare proximally and with the proximal phalanx of digit V distally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000929", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The fifth metatarsal bone is recognized by a rough eminence, the tuberosity, on the lateral side of its base. The base articulates behind, by a triangular surface cut obliquely in a transverse direction, with the cuboid; and medially, with the fourth metatarsal. On the medial part of its dorsal surface is inserted the tendon of the Peronæus tertius and on the dorsal surface of the tuberosity that of the Peronæus brevis. A strong band of the plantar aponeurosis connects the projecting part of the tuberosity with the lateral process of the tuberosity of the calcaneus. The plantar surface of the base is grooved for the tendon of the Abductor digiti quinti, and gives origin to the Flexor digiti quinti brevis. The base of the metatarsal is often injured and a particularly notorious fracture is the Jones fracture. When the tuberosity is broken, it is called a pseudo-Jones fracture or a dancer's fracture. This is a common fracture of the fifth metatarsal. Stress fractures are common in the fifth metatarsal among athletes[Wikipedia:Fifth_metatarsal_bone]." xsd:string {source="Wikipedia:Fifth_metatarsal_bone"} property_value: UBPROP:0000104 "5" xsd:nonNegativeInteger [Term] id: UBERON:0003655 name: molar tooth namespace: uberon def: "Molars are the rearmost and most complicated kind of tooth in most mammals." [https://github.com/obophenotype/uberon/issues/221, Wikipedia:Molar_(tooth)] subset: pheno_slim synonym: "dens molaris" EXACT [Wikipedia:Molar_(tooth)] synonym: "molar" RELATED [MA:0000350] synonym: "molaris" EXACT [BTO:0001759] xref: BTO:0001759 xref: CALOHA:TS-0637 xref: EMAPA:32897 xref: FMA:55638 xref: MA:0000350 xref: MESH:D008963 xref: NCIT:C33136 xref: SCTID:362115002 xref: UMLS:C0026367 {source="ncithesaurus:Molar_Tooth"} xref: Wikipedia:Molar_(tooth) is_a: UBERON:0013164 ! molariform tooth disjoint_from: UBERON:0003674 ! cuspid disjoint_from: UBERON:0007120 ! premolar tooth property_value: UBPROP:0000008 "Adult humans have twelve molars, in four groups of three at the back of the mouth. The third, rearmost molar in each group is called a wisdom tooth. It is the last tooth to appear, breaking through the surface of the gum at about the age of twenty, although this varies from individual to individual. Ethnicity can also have an impact on the age at which this occurs, with statistical variations between groups. The human mouth contains upper (maxillary) and lower (mandibular) molars. They are: maxillary first molar, maxillary second molar, maxillary third molar, mandibular first molar, mandibular second molar, and mandibular third molar." xsd:string [Term] id: UBERON:0003656 name: mesopodium bone namespace: uberon def: "A bone that is part of a mesopodial skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "basipodium bone" EXACT [MA:th] synonym: "carpal/tarsal bone" EXACT [MA:0000295] synonym: "mesopod bone" EXACT [] synonym: "mesopodial bone" EXACT [] xref: EMAPA:36579 xref: MA:0000295 xref: Wikipedia:Carpus_and_tarsus_of_land_vertebrates is_a: UBERON:0011250 ! autopod bone is_a: UBERON:0013630 {source="UBERON:cjm"} ! short bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0006716 ! mesopodium region relationship: part_of UBERON:0009878 {notes="https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern"} ! mesopodial skeleton property_value: UBPROP:0000008 "The carpus (wrist) and tarsus (ankle) of land vertebrates primitively had three rows of carpal or tarsal bones. Often some of these have become lost or fused in evolution. Three proximals. In the hand humans has all three. In the foot the middle proximal appears in 5-15% of people as an os trigonum. Centrale or os centrale, on the medial side. In humans and our closest relatives the African apes (chimpanzees and gorillas) it fuses to the scaphoid where it forms the articulation with the trapezoid bone; occasionally it stays separate. In Man's foot it is the navicular. Some early land vertebrates had more than one (up to three) os centrale per hand or foot. Distals, one per finger / toe at the base of each metacarpal or metatarsal. In mammals the 4th and 5th fuse. In the horse the 1st is lost" xsd:string {source="Wikipedia:Carpus_and_tarsus_of_land_vertebrates"} [Term] id: UBERON:0003657 name: limb joint namespace: uberon def: "Any joint that is part of a (free) limb." [https://orcid.org/0000-0002-6601-2165] comment: Most limb joints are synovial, but a few such as the tibiofibular joints are syndesmoses subset: grouping_class synonym: "joint of limb" EXACT [] synonym: "joint of limb skeletal system" EXACT [OBOL:automatic] synonym: "skeletal limb joint" EXACT [GO:0036023] xref: EMAPA:36501 xref: FMA:321558 xref: galen:LimbJoint xref: MA:0000691 xref: SCTID:312683002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002101 ! limb [Term] id: UBERON:0003658 name: hip muscle namespace: uberon def: "Any muscle organ that is part of a hip [Automatically generated definition]." [OBOL:automatic] synonym: "hip muscle organ" EXACT [OBOL:automatic] synonym: "hip region muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of hip" EXACT [OBOL:automatic] synonym: "muscle organ of hip region" EXACT [OBOL:automatic] synonym: "muscle organ of regio coxae" EXACT [OBOL:automatic] synonym: "regio coxae muscle organ" EXACT [OBOL:automatic] xref: MA:0000657 is_a: UBERON:0010890 ! pelvic complex muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0001464 ! hip relationship: part_of UBERON:0001464 ! hip relationship: part_of UBERON:0004475 {source="prolog"} ! musculature of hip [Term] id: UBERON:0003659 name: pedal digit muscle namespace: uberon def: "Any muscle organ that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "digit of foot muscle organ" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free lower limb muscle organ" EXACT [OBOL:automatic] synonym: "digitus pedis muscle organ" EXACT [OBOL:automatic] synonym: "foot digit muscle" EXACT [MA:0000648] synonym: "foot digit muscle" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "foot digit muscle organ" EXACT [OBOL:automatic] synonym: "hind limb digit muscle" EXACT [OBOL:accepted] synonym: "muscle organ of digit of foot" EXACT [OBOL:automatic] synonym: "muscle organ of digit of terminal segment of free lower limb" EXACT [OBOL:automatic] synonym: "muscle organ of digitus pedis" EXACT [OBOL:automatic] synonym: "muscle organ of foot digit" EXACT [OBOL:automatic] synonym: "muscle organ of terminal segment of free lower limb digit" EXACT [OBOL:automatic] synonym: "muscle organ of toe" EXACT [OBOL:automatic] synonym: "terminal segment of free lower limb digit muscle organ" EXACT [OBOL:automatic] synonym: "toe muscle organ" EXACT [OBOL:automatic] xref: EMAPA:37333 {source="MA:th"} xref: MA:0000648 is_a: UBERON:0001498 ! muscle of pes intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0003661 name: limb muscle namespace: uberon def: "Any muscle organ that is part of a limb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "limb muscle organ" EXACT [OBOL:accepted] synonym: "limb skeletal muscle" EXACT [OBOL:exploratory] synonym: "muscle organ of limb" EXACT [OBOL:accepted] xref: EMAPA:32700 xref: MA:0000692 is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002101 ! limb relationship: contributes_to_morphology_of UBERON:0001015 ! musculature relationship: part_of UBERON:0004480 {source="prolog"} ! musculature of limb [Term] id: UBERON:0003662 name: forelimb muscle namespace: uberon alt_id: UBERON:0005634 def: "Any muscle organ that is part of a forelimb." [OBOL:automatic] synonym: "arm muscle system" RELATED [EHDAA2:0000141] synonym: "fore limb muscle organ" EXACT [OBOL:automatic] synonym: "forelimb muscle organ" EXACT [OBOL:automatic] synonym: "free upper limb muscle" EXACT [FMA:37348] synonym: "muscle of free upper limb" EXACT [FMA:37348] synonym: "muscle of upper limb" EXACT [FMA:9621] synonym: "musculature of arm" RELATED PLURAL [] synonym: "musculature of the arm" RELATED PLURAL [] synonym: "upper limb skeletal muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "wing muscle" NARROW SENSU [Geisha:syn, NCBITaxon:8782, OBOL:automatic] xref: AAO:0000204 xref: BTO:0000479 xref: EMAPA:36049 xref: FMA:37348 is_a: UBERON:0003661 ! limb muscle is_a: UBERON:0014794 ! pectoral appendage muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0004481 {source="prolog"} ! musculature of upper limb property_value: UBPROP:0000012 "FMA and MA class actually refer to muscles of entire pectoral complex" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003663 name: hindlimb muscle namespace: uberon def: "Any muscle organ that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] subset: efo_slim synonym: "free lower limb muscle" EXACT [FMA:37368] synonym: "hind limb muscle organ" EXACT [OBOL:automatic] synonym: "hindlimb muscle organ" EXACT [OBOL:automatic] synonym: "inferior member muscle organ" EXACT [OBOL:automatic] synonym: "lower extremity muscle organ" EXACT [OBOL:automatic] synonym: "lower limb skeletal muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "muscle of free lower limb" EXACT [FMA:37368] synonym: "muscle of posterior limb" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "muscle organ of hind limb" EXACT [OBOL:automatic] synonym: "muscle organ of hindlimb" EXACT [OBOL:automatic] synonym: "muscle organ of inferior member" EXACT [OBOL:automatic] synonym: "muscle organ of lower extremity" EXACT [OBOL:automatic] xref: AAO:0000222 xref: EFO:0001928 xref: FMA:37368 is_a: UBERON:0003661 ! limb muscle is_a: UBERON:0014795 ! pelvic appendage muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0004482 {source="prolog"} ! musculature of lower limb [Term] id: UBERON:0003664 name: manual digit muscle namespace: uberon def: "Any muscle organ that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "digit of hand muscle organ" EXACT [OBOL:automatic] synonym: "digit of terminal segment of free upper limb muscle organ" EXACT [OBOL:automatic] synonym: "digitus manus muscle organ" EXACT [OBOL:automatic] synonym: "finger muscle organ" EXACT [OBOL:automatic] synonym: "fore limb digit muscle" EXACT [OBOL:accepted] synonym: "hand digit muscle" EXACT [MA:0000624] synonym: "hand digit muscle" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hand digit muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of digit of hand" EXACT [OBOL:automatic] synonym: "muscle organ of digit of terminal segment of free upper limb" EXACT [OBOL:automatic] synonym: "muscle organ of digitus manus" EXACT [OBOL:automatic] synonym: "muscle organ of finger" EXACT [OBOL:automatic] synonym: "muscle organ of hand digit" EXACT [OBOL:automatic] synonym: "muscle organ of terminal segment of free upper limb digit" EXACT [OBOL:automatic] synonym: "terminal segment of free upper limb digit muscle organ" EXACT [OBOL:automatic] xref: EMAPA:37331 {source="MA:th"} xref: MA:0000624 is_a: UBERON:0001500 ! muscle of manus intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0002389 ! manual digit [Term] id: UBERON:0003665 name: post-anal tail muscle namespace: uberon def: "A muscle organ that attaches to a tail vertebra [Automatically generated definition]." [OBOL:automatic] synonym: "caudal muscle" EXACT [] synonym: "muscle organ of post-vent region" EXACT [OBOL:automatic] synonym: "muscle organ of tail" EXACT [OBOL:automatic] synonym: "post-vent region muscle organ" EXACT [OBOL:automatic] synonym: "tail muscle" EXACT [MA:0000699] synonym: "tail muscle organ" EXACT [OBOL:automatic] xref: AAO:0000081 xref: BTO:0001905 xref: EMAPA:37759 {source="MA:th"} xref: MA:0000699 xref: SCTID:113230005 is_a: UBERON:0004518 ! muscle of vertebral column intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0001095 ! caudal vertebra relationship: attaches_to UBERON:0001095 ! caudal vertebra relationship: overlaps UBERON:0007812 ! post-anal tail property_value: UBPROP:0000012 "the BTO class may possibly refer to an invertebrate structure" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0003666 name: upper jaw molar namespace: uberon def: "A molar tooth that is part of a upper jaw [Automatically generated definition]." [OBOL:automatic] synonym: "maxillary secondary molar tooth" RELATED [FMA:55720] synonym: "molar tooth of upper jaw" EXACT [OBOL:automatic] synonym: "upper jaw molar tooth" EXACT [OBOL:automatic] synonym: "upper molar" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "upper molar tooth" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "upper permanent molar tooth" RELATED [FMA:55720] synonym: "upper secondary molar tooth" RELATED [FMA:55720] xref: EHDAA2:0002125 xref: EHDAA:8053 xref: EMAPA:17942 xref: FMA:55720 xref: MA:0001603 xref: NCIT:C49795 xref: UMLS:C1710580 {source="ncithesaurus:Upper_Jaw_Molar"} is_a: UBERON:0003655 ! molar tooth is_a: UBERON:0011593 ! maxillary tooth intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0003667 name: lower jaw molar namespace: uberon def: "A molar tooth that is part of a lower jaw [Automatically generated definition]." [OBOL:automatic] synonym: "lower jaw molar tooth" EXACT [OBOL:automatic] synonym: "lower molar" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "lower molar tooth" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "molar tooth of lower jaw" EXACT [OBOL:automatic] xref: EHDAA2:0001025 xref: EHDAA:8017 xref: EMAPA:17921 xref: FMA:290267 xref: MA:0001602 xref: NCIT:C49584 xref: UMLS:C1708756 {source="ncithesaurus:Lower_Jaw_Molar"} is_a: UBERON:0003655 ! molar tooth is_a: UBERON:0011594 ! dentary tooth intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0003672 name: dentition namespace: uberon def: "A collection of teeth arranged in some pattern in the mouth or other part of the body. The arrangement may be a simple row, a collection of rows, or a more elaborate structure, such as a toooth whorl." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "collection of teeth" RELATED [] synonym: "dentes" EXACT LATIN [FMA:75150, FMA:TA] synonym: "set of teeth" EXACT [FMA:75150] synonym: "teeth" EXACT [FMA:75150] synonym: "teeth" RELATED [] synonym: "teeth set" EXACT [FMA:75150] xref: AAO:0000126 xref: FMA:75150 xref: GAID:1249 xref: MESH:D003817 xref: NCIT:C13072 xref: SCTID:245543004 xref: UMLS:C0011443 {source="ncithesaurus:Dentition"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034925 ! anatomical collection intersection_of: UBERON:0034925 ! anatomical collection intersection_of: has_member UBERON:0001091 ! calcareous tooth relationship: has_member UBERON:0001091 ! calcareous tooth relationship: part_of UBERON:0010323 ! cranial skeletal system relationship: part_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! jaw region property_value: UBPROP:0000001 "Dentition refers to set of teeth, especially with regard to their number, kind, and arrangement, in the mouth.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000126", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The teeth collectively in the dental arch. Dentition ordinarily refers to the natural teeth in position in their alveoli. (MeSH[ncithesaurus:Dentition])" xsd:string {source="ncithesaurus:Dentition"} property_value: UBPROP:0000012 "In FMA this is an anatomical set" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003674 name: cuspid namespace: uberon def: "A tooth that is typically long and pointed and bearing a single cusp." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "canine" BROAD [] synonym: "canine (tooth)" RELATED [Wikipedia:Canine_tooth] synonym: "canine eminence" RELATED [Wikipedia:Canine_tooth] synonym: "canine teeth" RELATED PLURAL [GAID:1262, Wikipedia:Canine_tooth] synonym: "canine tooth" EXACT [FMA:55636] synonym: "caniniform tooth" NARROW [] synonym: "cuspis dentis" EXACT LATIN [FMA:55636, FMA:TA] synonym: "dens caninus" RELATED [Wikipedia:Canine_tooth] synonym: "dentes canini" RELATED LATIN [Wikipedia:Canine_tooth] synonym: "dogtooth (anatomy)" RELATED [Wikipedia:Canine_tooth] synonym: "eye teeth" RELATED PLURAL [Wikipedia:Canine_tooth] synonym: "eye tooth" RELATED [Wikipedia:Canine_tooth] synonym: "eyeteeth" RELATED PLURAL [Wikipedia:Canine_tooth] synonym: "eyetooth" RELATED [Wikipedia:Canine_tooth] synonym: "fang" RELATED [Wikipedia:Canine_tooth] xref: FMA:55636 xref: GAID:1262 xref: MESH:D003481 xref: NCIT:C32258 xref: SCTID:420817000 xref: SCTID:88719004 xref: UMLS:C0010482 {source="ncithesaurus:Canine_Tooth"} xref: Wikipedia:Canine_tooth is_a: UBERON:0001091 ! calcareous tooth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: has_quality PATO:0005021 ! unicuspidate disjoint_from: UBERON:0007120 ! premolar tooth relationship: has_part UBERON:0006844 {count="1", editor_note="cardinality not allowed with transitivity in OWL"} ! cusp of tooth relationship: has_quality PATO:0005021 ! unicuspidate relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/57/Azawakh_K9.jpg" xsd:anyURI property_value: RO:0002161 NCBITaxon:337687 {notes="Although there are a few exceptions, the dental formula for the great majority of cricetids is 1.0.0.3", source="Wikipedia:Cricetidae"} property_value: UBPROP:0000008 "Most species that develop them normally have four per individual, two in the upper jaw and two in the lower, separated within each jaw by its incisors; humans and dogs are examples. In most animals, canines are the anterior-most teeth in the maxillary bone. The four canines in humans are the two maxillary canines and the two mandibular canines." xsd:string [Term] id: UBERON:0003675 name: tooth crown namespace: uberon def: "The portion of the tooth covered by enamel." [ncithesaurus:Corona_Dentis] synonym: "anatomical crown" EXACT [FMA:55623] synonym: "corona dentis" EXACT LATIN [ncithesaurus:Corona_Dentis] synonym: "crown" RELATED [] synonym: "crown of tooth" EXACT [FMA:55623] synonym: "tooth crown" EXACT [FMA:55623] xref: FMA:55623 xref: GAID:1275 xref: MESH:D019228 xref: NCIT:C32375 xref: SCTID:362106009 xref: UMLS:C0226993 {source="ncithesaurus:Corona_Dentis"} is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004121 ! ectoderm-derived structure relationship: part_of UBERON:0001091 ! calcareous tooth [Term] id: UBERON:0003684 name: abdominal cavity namespace: uberon def: "The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity)." [UBERON:cjm] subset: efo_slim synonym: "cavitas abdominis" RELATED LATIN [GAID:17, Wikipedia:Abdominal_cavity] synonym: "cavity of abdominal compartment" EXACT [FMA:12266] synonym: "cavity of compartment of abdomen" EXACT [FMA:12266] synonym: "space of abdominal compartment" EXACT [FMA:12266] xref: EFO:0000213 xref: EMAPA:36505 xref: FMA:12266 xref: GAID:17 xref: galen:AbdominalCavity xref: MA:0003057 xref: MESH:D034841 xref: NCIT:C12664 xref: SCTID:361294009 xref: UMLS:C0230168 {source="ncithesaurus:Abdominal_Cavity"} xref: Wikipedia:Abdominal_cavity is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000916 ! abdomen intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen relationship: luminal_space_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0035819 ! abdominopelvic cavity property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI property_value: UBPROP:0000012 "in FMA this contains the pelvic cavity, but this is inconsistent with the concept of abdominopelvic cavity" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003685 name: cranial suture namespace: uberon def: "Fibrous joint in which the articulating bones or cartilages of the skull are connected by sutural ligaments (scant amount of collagenous dense connective tissue). Examples: sagittal suture, frontal suture." [FMA:71385, ISBN:3110148986, Wikipedia:Suture_(joint)] subset: pheno_slim subset: uberon_slim synonym: "cranium suture" EXACT [OBOL:automatic] synonym: "sutura" BROAD [] synonym: "suture" BROAD [FMA:71385] synonym: "suture joint of skull" EXACT [] synonym: "suture of cranium" EXACT [OBOL:automatic] xref: EMAPA:35263 xref: FMA:7493 xref: GAID:211 xref: MA:0001475 xref: MESH:D003393 xref: SCTID:244509003 xref: Wikipedia:Suture_(joint) is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0009198 {source="GO"} ! craniofacial suture intersection_of: UBERON:0002209 ! fibrous joint intersection_of: part_of UBERON:0003128 ! cranium relationship: contributes_to_morphology_of UBERON:0003128 ! cranium relationship: developmentally_induced_by UBERON:0002363 {source="PMID:16496288"} ! dura mater relationship: part_of UBERON:0003128 ! cranium property_value: UBPROP:0000202 FMA:71385 [Term] id: UBERON:0003687 name: foramen magnum namespace: uberon def: "In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]." [Wikipedia:Foramen_magnum] comment: Design pattern notes: check whether this fits the foramen design pattern subset: pheno_slim subset: vertebrate_core xref: AAO:0010826 xref: EMAPA:37868 {source="MA:th"} xref: FMA:75306 xref: GAID:228 xref: MESH:D005539 xref: NCIT:C12495 xref: SCTID:244679008 xref: TAO:0002045 xref: UMLS:C0016519 {source="ncithesaurus:Foramen_Magnum"} xref: Wikipedia:Foramen_magnum xref: ZFA:0005387 is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: conduit_for UBERON:0001896 ! medulla oblongata relationship: conduit_for UBERON:0001896 ! medulla oblongata relationship: located_in UBERON:0001676 ! occipital bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/39/Gray130.png" xsd:anyURI property_value: UBPROP:0000001 "Foramen in the occipital region of neurocranium to allow passage of spinal cord.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002045", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0003690 name: fused sacrum namespace: uberon def: "A collection of sacral vertebrae in the sacral region that are fused and part of the bony pelvis." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: human_reference_atlas subset: pheno_slim synonym: "os sacrum" RELATED LATIN [Wikipedia:Sacrum] synonym: "os sacrum [vertebrae sacrales I - V]" EXACT LATIN [FMA:16202, FMA:TA] synonym: "sacral bone" RELATED [FMA:16202] synonym: "sacrum" EXACT HUMAN_PREFERRED [FMA:16202] synonym: "sacrum [sacral vertebrae I - V]" EXACT [FMA:16202] synonym: "sacrum [sacral vertebrae I-V]" EXACT [FMA:16202] xref: CALOHA:TS-2201 xref: EFO:0003071 xref: FMA:16202 xref: GAID:241 xref: galen:Sacrum xref: MESH:D012447 xref: NCIT:C33508 xref: SCTID:264186006 xref: Wikipedia:Sacrum is_a: UBERON:0003828 ! abdominal segment bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0006075 ! sacral region of vertebral column is_a: UBERON:0008001 {source="FMA"} ! irregular bone intersection_of: UBERON:0006075 ! sacral region of vertebral column intersection_of: derived_from_ancestral_fusion_of UBERON:0001094 ! sacral vertebra intersection_of: part_of UBERON:0001270 ! bony pelvis relationship: anteriorly_connected_to UBERON:0004621 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! lumbar vertebra 5 relationship: derived_from_ancestral_fusion_of UBERON:0001094 ! sacral vertebra relationship: part_of UBERON:0001270 {source="FMA"} ! bony pelvis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ec/Gray95.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "sacral" xsd:string property_value: UBPROP:0000012 "the AAO class 'sacrum' is deliberately placed under 'sacral vertebra' rather than here" xsd:string {external_ontology="AAO"} [Term] id: UBERON:0003691 name: epidural space namespace: uberon def: "The outermost part of the spinal canal. It is the space within the canal (formed by the surrounding vertebrae) lying outside the dura mater." [Wikipedia:Epidural_space] synonym: "cavum epidurale" EXACT LATIN [Wikipedia:Epidural_space] synonym: "cavum extradurale" EXACT LATIN [Wikipedia:Epidural_space] synonym: "epidural cavity" RELATED [Wikipedia:Epidural_space] synonym: "extradural space" EXACT [FMA:71228] synonym: "spatium epidurale" EXACT LATIN [Wikipedia:Epidural_space] synonym: "spatium extradurale" EXACT LATIN [FMA:71228, FMA:TA] xref: FMA:71228 xref: GAID:243 xref: MESH:D004824 xref: SCTID:281866004 xref: Wikipedia:Epidural_space is_a: UBERON:0010276 ! space in vertebral column intersection_of: UBERON:0000464 ! anatomical space intersection_of: part_of UBERON:0006692 ! vertebral canal intersection_of: surrounds UBERON:0002363 ! dura mater relationship: part_of UBERON:0006692 ! vertebral canal relationship: surrounds UBERON:0002363 ! dura mater property_value: UBPROP:0000007 "epidural" xsd:string property_value: UBPROP:0000007 "extradural" xsd:string property_value: UBPROP:0000008 "In humans the epidural space contains lymphatics, spinal nerve roots, loose fatty tissue, small arteries, and a network of large, thin-walled blood vessels called the epidural venous plexus" xsd:string property_value: UBPROP:0000012 "in the FMA this is treated as a space of the head, but this ontology covers non-humans, where the space may continue into the tail" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003692 name: acromioclavicular joint namespace: uberon def: "Any joint connecting the acromonion of the scapula and clavicle." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Acromioclavicular_joint] synonym: "acromioclavicular articulation" RELATED [Wikipedia:Acromioclavicular_joint] synonym: "articulatio acromioclavicularis" RELATED LATIN [Wikipedia:Acromioclavicular_joint] synonym: "scapuloclavicular articulation" RELATED [Wikipedia:Acromioclavicular_joint] xref: FMA:25898 xref: GAID:249 xref: MESH:D000173 xref: NCIT:C32047 xref: SCTID:182166001 xref: UMLS:C0001208 {source="ncithesaurus:Acromioclavicular_Joint"} xref: Wikipedia:Acromioclavicular_joint is_a: UBERON:0011108 {source="FMA"} ! synovial joint of pectoral girdle is_a: UBERON:0016884 ! shoulder joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001105 ! clavicle bone intersection_of: connects UBERON:0002497 ! acromion relationship: connects UBERON:0001105 ! clavicle bone relationship: connects UBERON:0002497 ! acromion property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3b/Gray326.png" xsd:anyURI property_value: UBPROP:0000001 "The gliding joint formed by the outer extremity of the clavicle and the inner margin of the acromion process of the scapula." xsd:string {source="MESH:A02.835.583.032"} [Term] id: UBERON:0003694 name: atlanto-axial joint namespace: uberon def: "The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas." [Wikipedia:Atlanto-axial_joint] subset: pheno_slim synonym: "articulatio atlantoaxialis" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "articulatio atlantoepistrophica" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "atlanto axial joint" EXACT [GAID:250] synonym: "atlantoaxial" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "atlantoaxial joint" EXACT [GAID:250] synonym: "lateral atlanto-axial joint" RELATED [Wikipedia:Atlanto-axial_joint] synonym: "median atlanto-axial joint" RELATED [Wikipedia:Atlanto-axial_joint] xref: FMA:25524 xref: GAID:250 xref: MESH:D001268 xref: NCIT:C32157 xref: SCTID:361832004 xref: UMLS:C0004168 {source="ncithesaurus:Atlanto-axial_Joint"} xref: Wikipedia:Atlanto-axial_joint is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001092 ! vertebral bone 1 intersection_of: connects UBERON:0001093 ! vertebral bone 2 relationship: connects UBERON:0001092 ! vertebral bone 1 relationship: connects UBERON:0001093 ! vertebral bone 2 relationship: part_of UBERON:0011138 ! postcranial axial skeletal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d4/Gray304.png" xsd:anyURI [Term] id: UBERON:0003695 name: metacarpophalangeal joint namespace: uberon def: "The metacarpophalangeal joints (MCP) are of the condyloid kind, formed by the reception of the rounded heads of the metacarpal bones into shallow cavities on the proximal ends of the first phalanges, with the exception of that of the thumb, which presents more of the characters of a ginglymoid joint. Arthritis of the MCP is a distinguishing feature of Rheumatoid Arthritis, as opposed to the distal interphalangeal joint in osteoarthritis. [WP,unvetted]." [Wikipedia:Metacarpophalangeal_joint] subset: pheno_slim synonym: "articulationes metacarpophalangeae" RELATED LATIN [Wikipedia:Metacarpophalangeal_joint] synonym: "carpometacarpophalangeal joint" NARROW SENSU [NCBITaxon:8782] synonym: "knuckle" EXACT [https://orcid.org/0000-0001-5208-3432] synonym: "knuckles" EXACT PLURAL [https://orcid.org/0000-0001-5208-3432] synonym: "metacarpal joint" BROAD [FMA:35246] synonym: "metacarpal phalangeal joint" RELATED [HP:0004294] synonym: "metacarpo-phalangeal joint" EXACT [MA:0000453] synonym: "MP joint" EXACT [FMA:35246] xref: EMAPA:19302 xref: FMA:35246 xref: GAID:255 xref: galen:MetacarpoPhalangealJoint xref: MA:0000453 xref: MESH:D008662 xref: NCIT:C33106 xref: SCTID:280995004 xref: SCTID:370651001 xref: UMLS:C0025525 {source="ncithesaurus:Metacarpophalangeal_Joint"} xref: Wikipedia:Metacarpophalangeal_joint is_a: UBERON:0001489 ! manus joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002234 ! proximal phalanx of manus intersection_of: connects UBERON:0002374 ! metacarpal bone relationship: connects UBERON:0002234 ! proximal phalanx of manus relationship: connects UBERON:0002374 ! metacarpal bone relationship: part_of UBERON:0002389 ! manual digit property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/53/Gray337.png" xsd:anyURI property_value: editor_note "we follow FMA in making these joints part of digits. We include carpometacarpophalangeal joint as a synonym - these joints connect to the carpometacarpus - this is not necessarily inconsistent with the relationship for this class to metacarpal bone, as the carpometacarpus could be considered to have a metacarpal as part" xsd:string property_value: UBPROP:0000202 FMA:71364 [Term] id: UBERON:0003696 name: metatarsophalangeal joint namespace: uberon def: "The metatarsophalangeal articulations are the joints between the metatarsal bones of the foot and the proximal bones of the toes . They are condyloid joints meaning an elliptical or rounded surface (of the metatarsal bones) come close to the shallow cavities (of the proximal phalanges). The ligaments are the plantar and two collateral." [Wikipedia:Metatarsophalangeal_articulations] synonym: "articulationes metatarsophalangeae" RELATED LATIN [Wikipedia:Metatarsophalangeal_articulations] synonym: "metatarsal joint" RELATED [FMA:35222] synonym: "metatarsal-phalangeal joint" EXACT [PHENOSCAPE:ad] synonym: "metatarsalphalangeal joint" RELATED [Wikipedia:Metatarsophalangeal_articulations] synonym: "metatarsophalangeal" RELATED [Wikipedia:Metatarsophalangeal_articulations] synonym: "metatarsophalangeal articulation" RELATED [Wikipedia:Metatarsophalangeal_articulations] xref: FMA:35222 xref: GAID:258 xref: galen:MetatarsoPhalangealJoint xref: MESH:D008683 xref: NCIT:C33108 xref: SCTID:239747005 xref: SCTID:302535003 xref: SCTID:370752004 xref: UMLS:C0025589 {source="ncithesaurus:Metatarsophalangeal_Joint"} xref: Wikipedia:Metatarsophalangeal_articulations is_a: UBERON:0001487 ! pes joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0003867 ! distal phalanx of pes relationship: connects UBERON:0001448 ! metatarsal bone relationship: connects UBERON:0003867 ! distal phalanx of pes relationship: part_of UBERON:0001466 ! pedal digit property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray268.png" xsd:anyURI property_value: editor_note "we follow FMA in making these joints part of digits" xsd:string [Term] id: UBERON:0003697 name: abdominal wall namespace: uberon def: "The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles." [ncithesaurus:Abdominal_Wall] subset: pheno_slim synonym: "abdominal wall proper" RELATED [FMA:10429] synonym: "layers of the abdominal wall" RELATED [Wikipedia:Abdominal_wall] synonym: "paries abdominalis" EXACT [Wikipedia:Abdominal_wall] synonym: "paries abdominalis" RELATED LATIN [Wikipedia:Abdominal_wall] synonym: "wall of abdomen" EXACT [FMA:259054] synonym: "wall of abdomen proper" EXACT [FMA:10429] xref: EMAPA:37064 {source="MA:th"} xref: FMA:10429 xref: FMA:259054 xref: GAID:26 xref: MESH:D034861 xref: NCIT:C77608 xref: SCTID:181613000 xref: UMLS:C0836916 {source="ncithesaurus:Abdominal_Wall"} xref: Wikipedia:Abdominal_wall is_a: UBERON:0000060 ! anatomical wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI [Term] id: UBERON:0003698 name: subtalar joint namespace: uberon def: "A joint of the pes that connects the talus and the calcaneus." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Subtalar_joint] synonym: "articulatio subtalaris" EXACT LATIN [FMA:35198, FMA:TA] synonym: "articulatio talocalcanea" EXACT LATIN [FMA:35198, FMA:TA] synonym: "subtalar joint" EXACT [FMA:35198] synonym: "talocalcaneal articulation" RELATED [Wikipedia:Subtalar_joint] synonym: "talocalcaneal joint" RELATED [GAID:260] xref: FMA:35198 xref: GAID:260 xref: MESH:D013380 xref: NCIT:C33653 xref: SCTID:182213007 xref: UMLS:C0038593 {source="ncithesaurus:Subtalar_Joint"} xref: Wikipedia:Subtalar_joint is_a: UBERON:0008447 {source="MESH"} ! intertarsal joint intersection_of: UBERON:0002217 ! synovial joint intersection_of: connects UBERON:0001450 ! calcaneus intersection_of: connects UBERON:0002395 ! talus relationship: connects UBERON:0001450 ! calcaneus relationship: connects UBERON:0002395 ! talus property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/a/a9/Subtalar_Joint.PNG" xsd:anyURI [Term] id: UBERON:0003699 name: pubic symphysis namespace: uberon def: "The firm fibrocartilaginous joint in the median plane between the two opposing surfaces of the pubic bones, which are united by an interpubic disc of fibrocartilage as well as the superior and arcuate pubic ligaments." [MP:0009575, Wikipedia:Pubic_symphysis] subset: organ_slim subset: pheno_slim synonym: "interpubic articulation" RELATED [Wikipedia:Pubic_symphysis] synonym: "symphisis pubis" RELATED [Wikipedia:Pubic_symphysis] synonym: "symphysis pubica" RELATED LATIN [Wikipedia:Pubic_symphysis] synonym: "symphysis pubis" EXACT [FMA:16950] synonym: "symphysis pubis" RELATED LATIN [Wikipedia:Pubic_symphysis] xref: AAO:0000769 xref: EMAPA:37940 {source="MA:th"} xref: FMA:16950 xref: GAID:267 xref: MESH:D011631 xref: NCIT:C33425 xref: SCTID:182200001 xref: UMLS:C0034015 {source="ncithesaurus:Pubic_Symphisis"} xref: Wikipedia:Pubic_symphysis is_a: UBERON:0002216 {source="FMA"} ! symphysis is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0008114 ! joint of girdle relationship: connects UBERON:0011090 ! skeleton of right pelvic girdle relationship: connects UBERON:0011091 ! skeleton of left pelvic girdle relationship: contributes_to_morphology_of UBERON:0001275 ! pubis relationship: part_of UBERON:0001275 ! pubis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/51/Gray321.png" xsd:anyURI property_value: UBPROP:0000001 "Medial attachment of the two halves of the pelvic girdle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000769", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000008 "In birds, the pubic symphysis is present only in the ostrich, and the two hip bones are usually widely separated, making it easier to lay large eggs - Romer, Alfred Sherwood; Parsons, Thomas S. (1977). The Vertebrate Body. Philadelphia, PA: Holt-Saunders International. pp. 188-192. ISBN 0-03-910284-X." xsd:string [Term] id: UBERON:0003701 name: calcaneal tendon namespace: uberon def: "The Achilles tendon is a tendon of the posterior leg. It serves to attach the plantaris, gastrocnemius (calf) and soleus muscles to the calcaneus (heel) bone." [Wikipedia:Achilles_tendon] subset: pheno_slim synonym: "Achille's tendon" EXACT [] synonym: "Achilles tendon" EXACT [MA:0002993] synonym: "Achilles' tendon" EXACT [] synonym: "calcaneal tendon" EXACT [FMA:51061] synonym: "tendo Achillis" EXACT LATIN [Wikipedia:Achilles_tendon] synonym: "tendo calcaneus" EXACT LATIN [MA:0002993] xref: EMAPA:35853 xref: FMA:51061 xref: GAID:277 xref: MA:0002993 xref: MESH:D000125 xref: NCIT:C32043 xref: SCTID:181705009 xref: UMLS:C0001074 {source="ncithesaurus:Achilles_Tendon"} xref: Wikipedia:Achilles_tendon is_a: UBERON:0000043 {source="MA"} ! tendon is_a: UBERON:0004270 ! lower leg connective tissue is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0001450 ! calcaneus relationship: connects UBERON:0001383 ! muscle of leg relationship: connects UBERON:0001450 ! calcaneus relationship: part_of UBERON:0001665 {source="FMA"} ! triceps surae property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3c/Achilles-tendon.jpg" xsd:anyURI property_value: UBPROP:0000008 "reduced in non-human primates" xsd:string property_value: UBPROP:0000009 "bipedalism, running" xsd:string property_value: UBPROP:0000012 "in FMA this is a ligament, and part of the muscle" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003703 name: extrahepatic bile duct namespace: uberon def: "Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct." [MESH:A03.159.183.079] subset: pheno_slim subset: vertebrate_core synonym: "bile duct extrahepatic part" RELATED [MA:0002659] synonym: "extrahepatic biliary system" RELATED [GAID:281] xref: FMA:14678 xref: GAID:281 xref: MA:0002659 xref: MESH:D017734 xref: NCIT:C32573 xref: SCTID:276158002 xref: UMLS:C0206187 {source="ncithesaurus:Extrahepatic_Bile_Duct"} is_a: UBERON:0002394 ! bile duct property_value: editor_note "includes all the cystic duct, all the common bile duct and the extrahapetic part of the hepatic duct" xsd:string property_value: RO:0002171 UBERON:0002107 [Term] id: UBERON:0003704 name: intrahepatic bile duct namespace: uberon def: "Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct." [MESH:A03.159.183.158] subset: pheno_slim subset: vertebrate_core synonym: "bile duct intrahepatic part" EXACT [MA:0001630] synonym: "intrahepatic biliary system" RELATED [] xref: FMA:15766 xref: GAID:287 xref: MA:0001630 xref: MESH:D001653 xref: NCIT:C12677 xref: SCTID:362193005 xref: TAO:0005169 xref: UMLS:C0005401 {source="ncithesaurus:Intrahepatic_Bile_Duct"} xref: ZFA:0005169 is_a: UBERON:0002394 {source="FMA"} ! bile duct intersection_of: UBERON:0002394 ! bile duct intersection_of: part_of UBERON:0002107 ! liver relationship: contributes_to_morphology_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 {source="MA"} ! liver property_value: editor_note "includes the hepatic duct of the caudate lobe, and the intra- and inter- lobar bile ducts" xsd:string property_value: UBPROP:0000001 "Duct that collects bile from the bile ductules and connects to the extrahepatic bile duct.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005169", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0003709 name: circle of Willis namespace: uberon def: "A circle of arteries that supply blood to the brain. The Circle of Willis comprises the following arteries: Anterior cerebral artery (left and right); Anterior communicating artery; Internal carotid artery (left and right); Posterior cerebral artery (left and right); Posterior communicating artery (left and right).The basilar artery and middle cerebral arteries, supplying the brain, are also considered part of the circle." [Wikipedia:Circle_of_Willis] subset: pheno_slim synonym: "arterial circle" BROAD [Wikipedia:Circle_of_Willis] synonym: "arterial circle of Willis" EXACT [] synonym: "cerebral arterial circle" EXACT [GAID:486] synonym: "circulus arteriosus cerebri" RELATED LATIN [Wikipedia:Circle_of_Willis] synonym: "Willis circle" RELATED [GAID:486] xref: EHDAA2:0000252 xref: EHDAA:9758 xref: EMAPA:37829 {source="MA:th"} xref: FMA:50454 xref: GAID:486 xref: MESH:D002941 xref: neuronames:1468 xref: SCTID:362047009 xref: Wikipedia:Circle_of_Willis is_a: UBERON:0004573 ! systemic artery relationship: overlaps UBERON:0007142 {source="FMA-modified"} ! left internal carotid artery relationship: overlaps UBERON:0007143 {source="FMA-modified"} ! right internal carotid artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2e/Circle_of_Willis_en.svg" xsd:anyURI property_value: UBPROP:0000008 "In zebrafish, the circle of vessels comprised of the basal communicating artery (BCA) and posterior communicating segments (PCS) superficially resemble but are not homologous to the human circle of Willis" xsd:string {source="http://zfish.nichd.nih.gov/zfatlas/Intro%20Page/comparative.html"} [Term] id: UBERON:0003711 name: brachiocephalic vein namespace: uberon def: "The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava." [Wikipedia:Brachiocephalic_vein] subset: human_reference_atlas synonym: "brachiocephalic venous tree" EXACT [FMA:4723] synonym: "innomiate vein" RELATED [Wikipedia:Brachiocephalic_vein] synonym: "innominate trunk" RELATED [Wikipedia:Brachiocephalic_vein] synonym: "innominate vein" EXACT [FMA:4723] synonym: "innominate vein" RELATED [GAID:529, Wikipedia:Brachiocephalic_vein] synonym: "innominate veins" RELATED [Wikipedia:Brachiocephalic_vein] synonym: "vena brachiocephalica" RELATED LATIN [Wikipedia:Brachiocephalic_vein] synonym: "venae anonyma" RELATED LATIN [Wikipedia:Brachiocephalic_vein] xref: EHDAA2:0000182 xref: EHDAA:9868 xref: FMA:4723 xref: GAID:529 xref: galen:BrachiocephalicVein xref: MESH:D016121 xref: NCIT:C32816 xref: SCTID:181371003 xref: UMLS:C0006095 {source="ncithesaurus:Innominate_Vein"} xref: Wikipedia:Brachiocephalic_vein is_a: UBERON:0001638 ! vein relationship: connected_to UBERON:0001585 ! anterior vena cava relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0007204 ! brachiocephalic vasculature property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray1174.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003713 name: splenic vein namespace: uberon def: "A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein." [ncithesaurus:Splenic_Vein] subset: human_reference_atlas synonym: "lienal vein" RELATED [MA:0002164, Wikipedia:Splenic_vein] synonym: "vena lienalis" RELATED LATIN [Wikipedia:Splenic_vein] synonym: "vena splenica" EXACT LATIN [FMA:14331, FMA:TA] xref: EMAPA:37226 {source="MA:th"} xref: FMA:14331 xref: GAID:541 xref: galen:SplenicVein xref: MA:0002164 xref: MESH:D013162 xref: NCIT:C33608 xref: SCTID:278029005 xref: UMLS:C0038001 {source="ncithesaurus:Splenic_Vein"} xref: Wikipedia:Splenic_vein is_a: UBERON:0001638 ! vein relationship: connected_to UBERON:0001639 ! hepatic portal vein relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5b/Gray1189.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e4/Bilebladder.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003714 name: neural tissue namespace: uberon def: "Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature." [FMA:9642] synonym: "nerve tissue" EXACT [FMA:9642] synonym: "nervous tissue" EXACT [FMA:9642] synonym: "portion of neural tissue" EXACT [FMA:9642] xref: AAO:0000325 xref: AEO:0000123 xref: EHDAA2:0003123 xref: FMA:9642 xref: GAID:609 xref: MESH:D009417 xref: NCIT:C13052 xref: SCTID:91728009 xref: UMLS:C0027757 {source="ncithesaurus:Nervous_Tissue"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: has_part CL:0000125 ! glial cell intersection_of: has_part CL:0000540 ! neuron disjoint_from: UBERON:0004755 ! skeletal tissue relationship: has_part CL:0000125 ! glial cell relationship: has_part CL:0000540 ! neuron relationship: part_of UBERON:0001016 ! nervous system property_value: UBPROP:0000001 "One of the four types of tissue in traditional classifications. Cells forming the brain, spinal cord and peripheral nervous system.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000325", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000012 "FMA definition includes vasculature" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003715 name: splanchnic nerve namespace: uberon def: "The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia." [MP:0008318] subset: pheno_slim synonym: "splanchnic nerves" RELATED [BAMS:spn] synonym: "visceral nerve" RELATED [Wikipedia:Splanchnic_nerves] xref: BAMS:spn xref: EMAPA:37959 {source="MA:th"} xref: FMA:5883 xref: GAID:800 xref: MESH:D013153 xref: SCTID:264198001 xref: Wikipedia:Splanchnic_nerves is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0034729 ! sympathetic nerve intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0000916 ! abdomen relationship: contributes_to_morphology_of UBERON:0000013 ! sympathetic nervous system relationship: innervates UBERON:0000916 ! abdomen property_value: UBPROP:0000010 "All carry sympathetic fibers except for the pelvic splanchnic nerves, which carry parasympathetic fibers" xsd:string [Term] id: UBERON:0003716 name: recurrent laryngeal nerve namespace: uberon def: "A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch." [Wikipedia:Recurrent_laryngeal_nerve] synonym: "inferior laryngeal nerve" RELATED [GAID:804] synonym: "nervus laryngeus recurrens" EXACT LATIN [Wikipedia:Recurrent_laryngeal_nerve] synonym: "ramus recurrens" RELATED [AAO:0010754] synonym: "recurrent laryngeal nerve from vagus nerve" EXACT [] synonym: "recurrent nerve" BROAD [Wikipedia:Recurrent_laryngeal_nerve] synonym: "vagus X nerve recurrent laryngeal branch" EXACT [VHOG:0001347] xref: AAO:0010754 xref: FMA:6246 xref: GAID:804 xref: MESH:D012009 xref: SCTID:24227007 xref: VHOG:0001347 xref: Wikipedia:Recurrent_laryngeal_nerve is_a: UBERON:0011779 ! nerve of head region is_a: UBERON:0035642 ! laryngeal nerve relationship: branching_part_of UBERON:0001759 ! vagus nerve relationship: develops_from UBERON:0003117 {source="Wikipedia"} ! pharyngeal arch 6 relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda relationship: part_of UBERON:0001759 ! vagus nerve property_value: UBPROP:0000001 "Branch of the vagus nerve that separates from the vagus well postcranially, then continues anteriorly to innervate the larynx[AAO:0010754]." xsd:string {source="AAO:0010754"} [Term] id: UBERON:0003721 name: lingual nerve namespace: uberon def: "The lingual nerve is a branch of the mandibular nerve (CN V3), itself a branch of the trigeminal nerve, which supplies sensory innervation to the tongue. It also carries fibers from the facial nerve, which return taste information from the anterior two thirds of the tongue." [Wikipedia:Lingual_nerve] synonym: "lingual branch of trigeminal nerve" EXACT [] synonym: "trigeminal nerve lingual branch" EXACT [] synonym: "trigeminal V nerve lingual branch" EXACT [MA:0001102] xref: BAMS:5lg xref: EMAPA:19168 xref: FMA:53218 xref: GAID:835 xref: MA:0001102 xref: MESH:D008036 xref: SCTID:280260006 xref: Wikipedia:Lingual_nerve is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0011779 ! nerve of head region intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0001723 ! tongue relationship: branching_part_of UBERON:0000375 ! mandibular nerve relationship: innervates UBERON:0001723 ! tongue relationship: part_of UBERON:0000375 ! mandibular nerve [Term] id: UBERON:0003726 name: thoracic nerve namespace: uberon def: "The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls." [MESH:A08.800.800.720.800] synonym: "nervi thoracici" RELATED LATIN [Wikipedia:Thoracic_nerves] synonym: "nervus thoracis" EXACT LATIN [FMA:5860, FMA:TA] synonym: "pectoral nerve" RELATED [GAID:857] synonym: "thoracic spinal nerve" EXACT [FMA:5860] xref: FMA:5860 xref: GAID:857 xref: MESH:D013900 xref: neuronames:1725 xref: SCTID:360498003 xref: Wikipedia:Thoracic_nerves is_a: UBERON:0001780 ! spinal nerve intersection_of: UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0003038 ! thoracic spinal cord relationship: extends_fibers_into UBERON:0003038 ! thoracic spinal cord [Term] id: UBERON:0003727 name: intercostal nerve namespace: uberon def: "The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]." [Wikipedia:Intercostal_nerves] synonym: "anterior ramus of thoracic nerve" EXACT [FMA:6028] synonym: "anterior ramus of thoracic spinal nerve" EXACT [FMA:6028] synonym: "nervi intercostales" RELATED LATIN [Wikipedia:Intercostal_nerves] synonym: "ramus anterior, nervus thoracicus" EXACT [FMA:6028] synonym: "thoracic anterior ramus" EXACT [FMA:6028] synonym: "ventral ramus of thoracic spinal nerve" EXACT [FMA:6028] xref: EMAPA:18227 xref: FMA:6028 xref: GAID:858 xref: MESH:D007367 xref: NCIT:C32825 xref: SCTID:279568001 xref: UMLS:C1285089 {source="ncithesaurus:Intercostal_Nerve"} xref: Wikipedia:Intercostal_nerves is_a: UBERON:0001780 ! spinal nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b1/Gray819.png" xsd:anyURI [Term] id: UBERON:0003728 name: mediastinum namespace: uberon def: "The central part of the thoracic cavity enclosed by the left and right pleurae." [UBERON:cjm, Wikipedia:Mediastinum] subset: efo_slim subset: pheno_slim synonym: "mediastinal part of chest" EXACT [FMA:9826] xref: CALOHA:TS-2338 xref: EFO:0003057 xref: EMAPA:36001 xref: FMA:9826 xref: GAID:94 xref: MA:0003075 xref: MESH:D008482 xref: NCIT:C12748 xref: SCTID:181217005 xref: UMLS:C0025066 {source="ncithesaurus:Mediastinum"} xref: Wikipedia:Mediastinum is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0002224 ! thoracic cavity relationship: surrounded_by UBERON:0035431 {source="FMA"} ! mediastinal pleura property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ab/Mediastinum.png" xsd:anyURI property_value: UBPROP:0000007 "mediastinal" xsd:string [Term] id: UBERON:0003729 name: mouth mucosa namespace: uberon def: "A mucous membrane that lines the mouth." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "buccal mucosa" RELATED [GAID:951] synonym: "mouth mucosa" EXACT [FMA:59660] synonym: "mouth mucous membrane" EXACT [OBOL:accepted] synonym: "mouth organ mucosa" EXACT [OBOL:accepted] synonym: "mucosa of mouth" EXACT [OBOL:accepted] synonym: "mucosal lining of mouth" RELATED [MA:0002794] synonym: "mucous membrane of mouth" EXACT [FMA:59660] synonym: "oral mucosa" RELATED [GAID:951] synonym: "oral mucous membrane" EXACT [] synonym: "oral part of viscerocranial mucosa" EXACT [FMA:59660] synonym: "tunica mucosa oris" EXACT LATIN [FMA:59660, FMA:TA] synonym: "tunica mucosa oris" RELATED LATIN [Wikipedia:Oral_mucosa] xref: BTO:0002860 xref: CALOHA:TS-0716 xref: EMAPA:26937 xref: FMA:59660 xref: GAID:951 xref: MA:0002794 xref: MESH:D009061 xref: NCIT:C77637 xref: UMLS:C0026639 {source="ncithesaurus:Oral_Mucosa"} xref: Wikipedia:Oral_mucosa is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000165 ! mouth relationship: bounding_layer_of UBERON:0000165 ! mouth relationship: continuous_with UBERON:0000355 ! pharyngeal mucosa relationship: continuous_with UBERON:0001458 ! skin of lip relationship: contributes_to_morphology_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0000165 ! mouth property_value: IAO:0000232 "this is defined as any mucous membrane of the mouth - including palate, lips, uvula, etc. ncit split mouth/oral mucosa into lip and buccal. In future we may split into masticatory/keratinized (gingiva + hard palate) vs lining/non-keratinized (lips, cheeks, floor of mouth, soft palate). FMA distinguishes between mucosa of mouth and region of mouth (the latter including the buccal mucosa)" xsd:string property_value: UBPROP:0000001 "the mucous membrane epithelium of the mouth. It can be divided into three categories: masticatory, lining, and specialized[Wikipedia:Oral_mucosa]." xsd:string {source="Wikipedia:Oral_mucosa"} [Term] id: UBERON:0003821 name: metapodium bone namespace: uberon def: "A bone of the metapodial skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "metacarpal or metatarsal bone" EXACT [] synonym: "metacarpal/metatarsal" EXACT [] synonym: "metacarpal/metatarsal bone" EXACT [MA:0000301] synonym: "metapodi bone" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "metapodial bone" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "metapodium bone" EXACT [http://en.wiktionary.org/wiki/metapodial, https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37284 {source="MA:th"} xref: MA:0000301 is_a: UBERON:0003606 ! limb long bone is_a: UBERON:0012357 ! digitopodium bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0009877 ! metapodium region relationship: part_of UBERON:0010546 {notes="https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern"} ! metapodial skeleton [Term] id: UBERON:0003822 name: forelimb stylopod namespace: uberon def: "The part of the forelimb between pectoral region and the elbow, corresponding to the humerus." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "arm" RELATED INCONSISTENT [FMA:24890] synonym: "brachial region" EXACT [] synonym: "brachium" EXACT [VSAO:0005057] synonym: "fore propodium" EXACT [AAO:0000199] synonym: "forelimb propodium" EXACT [] synonym: "forelimb stylopodial element" EXACT [MA:th] synonym: "forelimb stylopodium" EXACT [OBOL:automatic] synonym: "proximal segment of free upper limb" EXACT [] synonym: "regio brachialis" EXACT LATIN [FMA:24890, FMA:TA] synonym: "stylopod of arm" EXACT [] synonym: "stylopod of forelimb" EXACT [] synonym: "upper arm" EXACT HUMAN_PREFERRED [MA:0000035] synonym: "wing stylopod" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: AAO:0000199 xref: EHDAA2:0002112 xref: EHDAA:4186 xref: EHDAA:6234 xref: EMAPA:17424 xref: FMA:24890 xref: galen:Arm xref: MA:0000035 xref: MESH:D001132 xref: NCIT:C32141 xref: SCTID:302538001 xref: UMLS:C0446516 {source="ncithesaurus:Arm"} xref: VHOG:0000343 xref: VSAO:0005057 is_a: UBERON:0002472 ! stylopod is_a: UBERON:0008785 ! upper limb segment intersection_of: UBERON:0002472 ! stylopod intersection_of: part_of UBERON:0002102 ! forelimb relationship: contributes_to_morphology_of UBERON:0002102 ! forelimb relationship: has_skeleton UBERON:0015053 ! humerus endochondral element relationship: part_of UBERON:0001460 {source="MA"} ! arm property_value: UBPROP:0000001 "Segment of the hindleg corresponding to the humerus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000887", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000343", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "anatomical usage, the term arm refers specifically to the segment between the shoulder and the elbow, while the segment between the elbow and wrist is the forearm. However, in common, literary, and historical usage, arm refers to the entire upper limb from shoulder to wrist. FMA uses the term Arm for this class, so we place it here. Naming conventions for pod terms under discussion within phenoscape group." xsd:string [Term] id: UBERON:0003823 name: hindlimb zeugopod namespace: uberon def: "The middle limb segment of the pelvic free limb, between the autopod and stylopod segments. Includes as parts the hindlimb zeugopodial skeleton, which includes as parts the tibia and fibula, or their cartilage precursors, or evolutionary variants." [PHENOSCAPE:curators] subset: efo_slim subset: pheno_slim synonym: "crus" EXACT [VSAO:0005060] synonym: "crus of hindlimb" EXACT [] synonym: "hind epipodium" RELATED INCONSISTENT [] synonym: "hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "hind limb zeudopodium" EXACT [VHOG:0000348] synonym: "hind limb zeugopod" EXACT [OBOL:automatic] synonym: "hindlimb epipodium" EXACT [] synonym: "hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "hindlimb zeudopodium" EXACT [VHOG:0000348] synonym: "hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "hindlimb zeugopodium" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb" EXACT [FMA:24979] synonym: "leg" RELATED INCONSISTENT [FMA:24979, MESH:A01.378.610.500] synonym: "lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "lower leg" EXACT HUMAN_PREFERRED [MA:0000051] synonym: "middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "shank" EXACT [VSAO:0005060] synonym: "zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb" EXACT [OBOL:automatic] xref: EFO:0003051 xref: EHDAA2:0001030 xref: EHDAA:5165 xref: EHDAA:6190 xref: EMAPA:17496 xref: FMA:24979 xref: galen:Leg xref: MA:0000051 xref: MESH:D007866 xref: NCIT:C32974 xref: SCTID:244015008 xref: UMLS:C1140621 {source="ncithesaurus:Leg"} xref: VHOG:0000348 xref: VSAO:0005060 xref: Wikipedia:Forearm is_a: UBERON:0002471 ! zeugopod is_a: UBERON:0008784 ! lower limb segment intersection_of: UBERON:0002471 ! zeugopod intersection_of: part_of UBERON:0002103 ! hindlimb relationship: contributes_to_morphology_of UBERON:0002103 ! hindlimb relationship: has_skeleton UBERON:0010720 ! hindlimb zeugopod skeleton relationship: part_of UBERON:0000978 {source="MA"} ! leg property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000348", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "sural" xsd:string property_value: UBPROP:0000012 "FMA:24979 denotes the middle segment (zeugopod), its placement here is correct. See obo-anatomy archives for discussion" xsd:string {external_ontology="FMA"} property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group. TODO - add distinct term for skeleton and place AAO class here" xsd:string [Term] id: UBERON:0003824 name: nerve of thoracic segment namespace: uberon def: "A nerve that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of thorax" EXACT [OBOL:automatic] synonym: "thoracic segment nerve" EXACT [MA:0000562] synonym: "thorax nerve" EXACT [OBOL:automatic] synonym: "upper body nerve" RELATED [MA:0000562] xref: EMAPA:37265 {source="MA:th"} xref: MA:0000562 xref: MESH:D013900 xref: SCTID:359876006 is_a: UBERON:0003439 ! nerve of trunk region intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0003825 name: nerve of abdominal segment namespace: uberon def: "A nerve that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment nerve" EXACT [MA:0000528] xref: EMAPA:37061 {source="MA:th"} xref: MA:0000528 is_a: UBERON:0003439 ! nerve of trunk region intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0003826 name: upper leg bone namespace: uberon def: "A bone that is part of a hindlimb stylopod [Automatically generated definition]." [https://sourceforge.net/tracker/index.php?func=detail&aid=3586533&group_id=76834&atid=1205376, OBOL:automatic] comment: May be merged into femur. See https://sourceforge.net/tracker/index.php?func=detail&aid=3586533&group_id=76834&atid=1205376 synonym: "femur" RELATED [https://sourceforge.net/tracker/index.php?func=detail&aid=3586533&group_id=76834&atid=1205376] xref: EMAPA:35893 xref: MA:0000682 is_a: UBERON:0005893 ! leg bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0003827 name: thoracic segment bone namespace: uberon def: "A bone that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "bone of thorax" EXACT [OBOL:automatic] synonym: "bone organ of thorax" EXACT [OBOL:automatic] synonym: "thorax bone" EXACT [OBOL:automatic] synonym: "thorax bone organ" EXACT [OBOL:automatic] synonym: "upper body bone" RELATED [MA:0000559] xref: EMAPA:37247 {source="MA:th"} xref: MA:0000559 xref: SCTID:426649006 is_a: UBERON:0003463 ! trunk bone is_a: UBERON:0005181 ! thoracic segment organ intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0003828 name: abdominal segment bone namespace: uberon def: "A bone that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk bone" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk bone organ" EXACT [OBOL:automatic] synonym: "bone of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "bone organ of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37058 {source="MA:th"} xref: MA:0000525 is_a: UBERON:0003463 ! trunk bone is_a: UBERON:0005173 ! abdominal segment element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0003829 name: urethra muscle tissue namespace: uberon def: "Any muscle tissue that is part of the urethra." [UBERON:cjm] synonym: "urethral muscle layer" RELATED [MA:0002649] xref: EMAPA:37787 {source="MA:th"} xref: MA:0002649 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005090 ! muscle structure intersection_of: UBERON:0005090 ! muscle structure intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0003830 name: thoracic segment muscle namespace: uberon def: "Any muscle organ that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "muscle organ of thorax" EXACT [OBOL:automatic] synonym: "thorax muscle organ" EXACT [OBOL:automatic] synonym: "upper body muscle" RELATED [MA:0000561] xref: MA:0000561 is_a: UBERON:0001774 ! skeletal muscle of trunk is_a: UBERON:0005181 ! thoracic segment organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0004464 {source="prolog"} ! musculature of thorax [Term] id: UBERON:0003831 name: respiratory system muscle namespace: uberon def: "Any muscle organ that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "muscle organ of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system muscle organ" EXACT [OBOL:automatic] xref: EMAPA:35733 xref: MA:0001828 is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0003832 name: esophagus muscle namespace: uberon def: "Any muscle organ that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal muscle" EXACT [] synonym: "esophagus muscle organ" EXACT [OBOL:automatic] synonym: "gullet muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of esophagus" EXACT [OBOL:automatic] synonym: "muscle organ of gullet" EXACT [OBOL:automatic] synonym: "muscle organ of oesophagus" EXACT [OBOL:automatic] synonym: "oesophagus muscle organ" EXACT [OBOL:automatic] xref: EMAPA:26983 xref: MA:0002682 xref: SCTID:360961009 is_a: UBERON:0001630 ! muscle organ is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001096 {source="MA"} ! wall of esophagus property_value: editor_note "merge muscle and muscle layer?" xsd:string [Term] id: UBERON:0003833 name: abdominal segment muscle namespace: uberon def: "A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk muscle organ" EXACT [OBOL:automatic] synonym: "muscle organ of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37060 {source="MA:th"} xref: MA:0000527 is_a: UBERON:0001774 ! skeletal muscle of trunk is_a: UBERON:0005173 ! abdominal segment element intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0003834 name: thoracic segment blood vessel namespace: uberon def: "A blood vessel that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of thorax" EXACT [OBOL:automatic] synonym: "thorax blood vessel" EXACT [OBOL:automatic] synonym: "upper body blood vessel" RELATED [MA:0000558] xref: EMAPA:37238 {source="MA:th"} xref: MA:0000558 is_a: UBERON:0003513 ! trunk blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0003835 name: abdominal segment blood vessel namespace: uberon def: "A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37057 {source="MA:th"} xref: MA:0000524 is_a: UBERON:0003513 ! trunk blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0003836 name: abdominal segment skin namespace: uberon def: "A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk skin" EXACT [OBOL:automatic] synonym: "skin of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37063 {source="MA:th"} xref: FMA:264898 xref: MA:0000530 is_a: UBERON:0001085 ! skin of trunk intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0003837 name: thoracic segment connective tissue namespace: uberon def: "A portion of connective tissue that is part of a thorax [Automatically generated definition]." [OBOL:automatic] synonym: "connective tissue of thorax" EXACT [OBOL:automatic] synonym: "portion of connective tissue of thorax" EXACT [OBOL:automatic] synonym: "textus connectivus of thorax" EXACT [OBOL:automatic] synonym: "thorax connective tissue" EXACT [OBOL:automatic] synonym: "thorax portion of connective tissue" EXACT [OBOL:automatic] synonym: "thorax textus connectivus" EXACT [OBOL:automatic] synonym: "upper body connective tissue" RELATED [MA:0000560] xref: EMAPA:37253 {source="MA:th"} xref: MA:0000560 is_a: UBERON:0003586 ! trunk connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0003838 name: abdominal segment connective tissue namespace: uberon def: "A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]." [OBOL:automatic] synonym: "abdominal segment of trunk connective tissue" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk portion of connective tissue" EXACT [OBOL:automatic] synonym: "abdominal segment of trunk textus connectivus" EXACT [OBOL:automatic] synonym: "connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "portion of connective tissue of abdominal segment of trunk" EXACT [OBOL:automatic] synonym: "textus connectivus of abdominal segment of trunk" EXACT [OBOL:automatic] xref: EMAPA:37059 {source="MA:th"} xref: MA:0000526 is_a: UBERON:0003586 ! trunk connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0003839 name: forelimb joint namespace: uberon def: "A limb joint that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "anteriormost limb joint of limb" EXACT [OBOL:automatic] synonym: "anteriormost limb limb joint" EXACT [OBOL:automatic] synonym: "fore limb joint of limb" EXACT [OBOL:automatic] synonym: "fore limb limb joint" EXACT [OBOL:automatic] synonym: "forelimb joint of limb" EXACT [OBOL:automatic] synonym: "forelimb limb joint" EXACT [OBOL:automatic] synonym: "joint of free upper limb" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "joint of limb of anteriormost limb" EXACT [OBOL:automatic] synonym: "joint of limb of fore limb" EXACT [OBOL:automatic] synonym: "joint of limb of forelimb" EXACT [OBOL:automatic] synonym: "joint of limb of superior member" EXACT [OBOL:automatic] synonym: "joint of limb of upper extremity" EXACT [OBOL:automatic] synonym: "limb joint of anteriormost limb" EXACT [OBOL:automatic] synonym: "limb joint of fore limb" EXACT [OBOL:automatic] synonym: "limb joint of forelimb" EXACT [OBOL:automatic] synonym: "limb joint of superior member" EXACT [OBOL:automatic] synonym: "limb joint of upper extremity" EXACT [OBOL:automatic] synonym: "superior member joint of limb" EXACT [OBOL:automatic] synonym: "superior member limb joint" EXACT [OBOL:automatic] synonym: "upper extremity joint of limb" EXACT [OBOL:automatic] synonym: "upper extremity limb joint" EXACT [OBOL:automatic] synonym: "wing joint" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:19204 xref: MA:0000614 is_a: UBERON:0003657 ! limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 ! forelimb property_value: UBPROP:0000202 FMA:71344 [Term] id: UBERON:0003840 name: hindlimb joint namespace: uberon def: "A limb joint that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "hind limb joint of limb" EXACT [OBOL:automatic] synonym: "hind limb limb joint" EXACT [OBOL:automatic] synonym: "hindlimb joint of limb" EXACT [OBOL:automatic] synonym: "hindlimb limb joint" EXACT [OBOL:automatic] synonym: "inferior member joint of limb" EXACT [OBOL:automatic] synonym: "inferior member limb joint" EXACT [OBOL:automatic] synonym: "joint of free lower limb" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "joint of limb of hind limb" EXACT [OBOL:automatic] synonym: "joint of limb of hindlimb" EXACT [OBOL:automatic] synonym: "joint of limb of inferior member" EXACT [OBOL:automatic] synonym: "joint of limb of lower extremity" EXACT [OBOL:automatic] synonym: "joint of lower limb" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "limb joint of hind limb" EXACT [OBOL:automatic] synonym: "limb joint of hindlimb" EXACT [OBOL:automatic] synonym: "limb joint of inferior member" EXACT [OBOL:automatic] synonym: "limb joint of lower extremity" EXACT [OBOL:automatic] synonym: "lower extremity joint of limb" EXACT [OBOL:automatic] synonym: "lower extremity limb joint" EXACT [OBOL:automatic] xref: EMAPA:32635 xref: MA:0000662 xref: SCTID:304573000 is_a: UBERON:0003657 ! limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 ! hindlimb property_value: UBPROP:0000202 FMA:71348 [Term] id: UBERON:0003841 name: autopod joint namespace: uberon def: "A limb joint that is part of an autopod [Automatically generated definition]." [OBOL:automatic] synonym: "autopod joint of limb" EXACT [OBOL:automatic] synonym: "autopod limb joint" EXACT [OBOL:automatic] synonym: "distal free limb segment joint of limb" EXACT [OBOL:automatic] synonym: "distal free limb segment limb joint" EXACT [OBOL:automatic] synonym: "joint of limb of autopod" EXACT [OBOL:automatic] synonym: "joint of limb of distal free limb segment" EXACT [OBOL:automatic] synonym: "limb joint of autopod" EXACT [OBOL:automatic] synonym: "limb joint of distal free limb segment" EXACT [OBOL:automatic] synonym: "paw joint" RELATED [MA:0002715] xref: EMAPA:35160 xref: MA:0002715 is_a: UBERON:0003657 ! limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0002470 ! autopod region relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0003842 name: neural tube lumen namespace: uberon alt_id: UBERON:0005713 def: "An anatomical space that surrounded_by a neural tube." [OBOL:automatic] synonym: "cavity of neural tube" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "central lumen" RELATED [] synonym: "lumen of neural tube" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "neural lumen" RELATED [EHDAA:2889] synonym: "neural tube neural lumen" EXACT [EHDAA2:0001269] synonym: "neurocoel" RELATED [VHOG:0001119] synonym: "prosencoel" NARROW [] xref: AAO:0011073 xref: EHDAA2:0001269 xref: EHDAA:2889 xref: EHDAA:914 xref: EMAPA:16167 xref: VHOG:0001119 xref: XAO:0000252 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001049 ! neural tube relationship: luminal_space_of UBERON:0001049 ! neural tube relationship: part_of UBERON:0001049 ! neural tube property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001119", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003843 name: dental epithelium namespace: uberon def: "Epithelium that is part of a developing tooth or dental organ." [https://github.com/cerivs/zebrafish-anatomical-ontology/issues/107, ZFA:0005134] subset: vertebrate_core synonym: "dental epithelia" EXACT PLURAL [ZFA:0005134] synonym: "dental epithelium" EXACT [ZFA:0005134] synonym: "odontogenic epithelium" EXACT [] synonym: "reduced enamel epithelium" RELATED [BTO:0001723] synonym: "tooth epithelium" EXACT [] xref: AAO:0011027 xref: BTO:0001723 xref: EMAPA:32903 xref: MA:0003151 xref: NCIT:C54296 xref: TAO:0005134 xref: UMLS:C1709309 {source="ncithesaurus:Odontogenic_Epithelial_Remnants"} xref: VHOG:0001443 xref: XAO:0003203 xref: ZFA:0005134 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005176 ! tooth enamel organ relationship: develops_from UBERON:0004362 {notes="epithelium", source="JB"} ! pharyngeal arch 1 relationship: part_of UBERON:0005176 ! tooth enamel organ property_value: editor_note "see comments for dental organ." xsd:string property_value: editor_note "todo - full developmental relationships" xsd:string property_value: UBPROP:0000011 "In the developing molar dentition of the mouse, tooth inductive po- tential resides in the dental epithelium until embryonic day (E)12.5 (3). Thereafter, tooth inductive potential shifts to neural crest-derived dental mesenchyme, which acquires the ability to direct tooth formation in nonodontogenic tissues (3, 4)" xsd:string {source="PMID:10954731"} [Term] id: UBERON:0003848 name: gonadal vein namespace: uberon def: "In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]." [Wikipedia:Gonadal_vein] synonym: "gonad vein" EXACT [OBOL:automatic] synonym: "gonada vein" EXACT [OBOL:automatic] synonym: "vein of gonad" EXACT [OBOL:automatic] synonym: "vein of gonada" EXACT [OBOL:automatic] xref: EHDAA2:0000719 xref: EHDAA:8703 xref: SCTID:278192008 xref: VHOG:0001340 xref: Wikipedia:Gonadal_vein is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: attaches_to UBERON:0000991 ! gonad relationship: attaches_to UBERON:0000991 ! gonad relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/da/Gray1120.png" xsd:anyURI [Term] id: UBERON:0003849 name: mesencephalic neural crest namespace: uberon def: "A neural crest that has_potential_to_developmentally_contribute_to a midbrain." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "mesencephalic neural crest" EXACT [ZFA:0000935] synonym: "neural crest midbrain" EXACT [ZFA:0000935] xref: EFO:0003591 xref: EHDAA2:0001101 xref: EHDAA:360 xref: TAO:0000935 xref: VHOG:0000796 xref: ZFA:0000935 is_a: UBERON:0002342 ! neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: has_potential_to_developmentally_contribute_to UBERON:0001891 ! midbrain relationship: has_potential_to_developmentally_contribute_to UBERON:0001891 ! midbrain property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000796", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003850 name: telencephalon neural crest namespace: uberon def: "A neural crest that has_potential_to_developmentally_contribute_to a telencephalon." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "neural crest telencephalon" EXACT [ZFA:0000812] xref: EFO:0003574 xref: RETIRED_EHDAA2:0001991 xref: TAO:0000812 xref: VHOG:0000799 xref: ZFA:0000812 is_a: UBERON:0002342 ! neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: has_potential_to_developmentally_contribute_to UBERON:0001893 ! telencephalon relationship: has_potential_to_developmentally_contribute_to UBERON:0001893 ! telencephalon property_value: UBPROP:0000001 "Cranial neural crest that is part of the telencephalon.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000812", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000799", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003852 name: rhombencephalon neural crest namespace: uberon def: "A neural crest that has_potential_to_developmentally_contribute_to a hindbrain." [OBOL:automatic] subset: vertebrate_core synonym: "neural crest hindbrain" EXACT [ZFA:0007063] synonym: "rhombencephalic neural crest" EXACT [ZFA:0007063] synonym: "rhombomere neural crest" RELATED [EMAPA:35747] xref: EHDAA2:0001628 xref: EHDAA:362 xref: EMAPA:35747 xref: TAO:0007063 xref: VHOG:0001210 xref: ZFA:0007063 is_a: UBERON:0002342 ! neural crest is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: has_potential_to_developmentally_contribute_to UBERON:0002028 ! hindbrain relationship: has_potential_to_developmentally_contribute_to UBERON:0002028 ! hindbrain property_value: UBPROP:0000001 "Cranial neural crest that is part of the hindbrain.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0007063", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001210", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003853 name: spinal cord neural crest namespace: uberon def: "A neural crest that has_potential_to_developmentally_contribute_to a spinal cord." [OBOL:automatic] synonym: "neural crest spinal cord" EXACT [VHOG:0001006] synonym: "spinal neural crest" RELATED [VHOG:0001006] xref: EHDAA:696 xref: EMAPA:16163 xref: EMAPA:16881 xref: VHOG:0001006 is_a: UBERON:0002342 ! neural crest intersection_of: UBERON:0002342 ! neural crest intersection_of: has_potential_to_developmentally_contribute_to UBERON:0002240 ! spinal cord relationship: has_potential_to_developmentally_contribute_to UBERON:0002240 ! spinal cord property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...)[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001006", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003854 name: spinal cord neural plate namespace: uberon def: "A neural plate that develops_from a future spinal cord." [OBOL:automatic] synonym: "neural plate of spinal cord" EXACT [OBOL:automatic] xref: FMA:312957 xref: TAO:0007021 xref: VHOG:0000439 xref: ZFA:0007021 is_a: UBERON:0003075 ! neural plate intersection_of: UBERON:0003075 ! neural plate intersection_of: develops_from UBERON:0006241 ! future spinal cord relationship: develops_from UBERON:0006241 {source="ZFA"} ! future spinal cord property_value: UBPROP:0000001 "Neural plate that is part of the spinal cord. [Bgee_curator][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000439", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "(...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...)[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000439", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.28", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003855 name: gonad mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing gonad [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "gonada mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of gonad" EXACT [OBOL:automatic] synonym: "mesenchyme of gonada" EXACT [OBOL:automatic] xref: EHDAA:5012 xref: EMAPA:16858 xref: EMAPA:17385 xref: VHOG:0001090 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000991 ! gonad relationship: part_of UBERON:0000991 ! gonad [Term] id: UBERON:0003856 name: uncondensed odontogenic mesenchyme namespace: uberon def: "Mesenchyme enclosed by a dental organ that gives rise to an odontogenic papilla." [https://github.com/cerivs/zebrafish-anatomical-ontology/issues/107, https://orcid.org/0000-0002-6601-2165] subset: vertebrate_core synonym: "dental mesenchyme" EXACT [ZFA:0005139] synonym: "dental organ mesenchyme" EXACT [OBOL:automatic] synonym: "enamel organ mesenchyme" EXACT [OBOL:automatic] synonym: "tooth enamel organ mesenchyme" EXACT [OBOL:automatic] synonym: "tooth mesenchyme" EXACT [OBOL:automatic] xref: EMAPA:32891 xref: MA:0003152 xref: TAO:0005139 xref: VHOG_RETIRED:0001444 xref: ZFA:0005139 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest is_a: UBERON:0007529 ! loose mesenchyme tissue intersection_of: UBERON:0007529 ! loose mesenchyme tissue intersection_of: part_of UBERON:0008281 ! tooth bud relationship: adjacent_to UBERON:0005176 ! tooth enamel organ relationship: develops_from UBERON:0007213 {notes="see comments"} ! mesenchyme derived from head neural crest relationship: develops_from UBERON:0010259 {gci_relation="part_of", gci_filler="NCBITaxon:32523", source="JB"} ! 1st arch mesenchyme from neural crest relationship: part_of UBERON:0008281 ! tooth bud property_value: editor_note "we follow ZFA in introducing an additional distinction between the dental papilla and the (uncondensed) mesenchyme. Note that in some species such as zebrafish teeth are not part of the mouth, and sharks have dermal denticles which share similar developmental origins with teeth. For now we assume a NC origin for all and add a taxon restriction to 1st arch mesenchyme" xsd:string property_value: UBPROP:0000001 "Mesenchyme enclosed by dental organ.[MP]" xsd:string {ontology="MP", source="J:153554"} property_value: UBPROP:0000001 "Mesenchyme enclosed by dental organ.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005139", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0003859 name: forelimb mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "anteriormost limb mesenchyme" EXACT [OBOL:automatic] synonym: "fore limb mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of anteriormost limb" EXACT [OBOL:automatic] synonym: "mesenchyme of fore limb" EXACT [OBOL:automatic] synonym: "mesenchyme of forelimb" EXACT [OBOL:automatic] synonym: "mesenchyme of superior member" EXACT [OBOL:automatic] synonym: "mesenchyme of upper extremity" EXACT [OBOL:automatic] synonym: "superior member mesenchyme" EXACT [OBOL:automatic] synonym: "upper extremity mesenchyme" EXACT [OBOL:automatic] synonym: "wing mesenchyme" NARROW SENSU [Geisha:syn, NCBITaxon:8782, OBOL:automatic] xref: EMAPA:32628 xref: VHOG:0001109 is_a: UBERON:0009749 ! limb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0003860 name: hindlimb mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb mesenchyme" EXACT [OBOL:automatic] synonym: "inferior member mesenchyme" EXACT [OBOL:automatic] synonym: "lower extremity mesenchyme" EXACT [OBOL:automatic] synonym: "mesenchyme of hind limb" EXACT [OBOL:automatic] synonym: "mesenchyme of hindlimb" EXACT [OBOL:automatic] synonym: "mesenchyme of inferior member" EXACT [OBOL:automatic] synonym: "mesenchyme of lower extremity" EXACT [OBOL:automatic] xref: EMAPA:32637 xref: VHOG:0001074 is_a: UBERON:0009749 ! limb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0003861 name: neural arch namespace: uberon def: "Posterior part of a vertebra that consists of a pair of pedicles and a pair of laminae, and supports seven processes: four articular processes, two transverse processes one spinous process[WP]. ZFA: A neural arch encloses the neural canal and typically meets its partner to form a neural spine." [Wikipedia:Vertebral_arch] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "arcus vertebra" EXACT [Wikipedia:Vertebral_arch] synonym: "arcus vertebrae" EXACT PLURAL [Wikipedia:Vertebral_arch] synonym: "arcus vertebrae" RELATED LATIN [Wikipedia:Vertebral_arch] synonym: "arcus vertebrae (vertebralis)" EXACT [FMA:11946] synonym: "dorsal arcocentrum" EXACT [ZFA:0001066] synonym: "vertebra dorsal arch" RELATED [MA:0001453] synonym: "vertebra neural arch" BROAD SENSU [MA:0001453] xref: AAO:0000725 xref: EFO:0003618 xref: FMA:11946 xref: MA:0001453 xref: NCIT:C32138 xref: SCTID:317373001 xref: TAO:0001066 xref: UMLS:C0223076 {source="ncithesaurus:Arch_of_the_Vertebra"} xref: VHOG:0001670 xref: Wikipedia:Vertebral_arch xref: ZFA:0001066 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0010358 ! arch of centrum of vertebra relationship: develops_from UBERON:0006063 ! cartilaginous neural arch property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray82.png" xsd:anyURI property_value: UBPROP:0000001 "A neural arch encloses the neural canal and typically meets its partner to form a neural spine. The neural arch can be a replacement ossification of the basidorsal cartilage or can form directly in membrane bone.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001066", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Bony arch perched on the vertebral centrum; successive arches enclose the neural canal that surrounds and protects the spinal cord dorsally.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000725", ontology="AAO", source="AAO:Pugener_2002"} property_value: UBPROP:0000001 "the dorsal bony and/or cartilaginous part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" xsd:string {source="MP:0004599:csmith"} property_value: UBPROP:0000002 "relationship loss: develops_from basidorsal (TAO:0001060)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001066", ontology="TAO"} property_value: UBPROP:0000003 "(...) certain common components [of vertebral structure] are found in nearly all vertebrate. A representative vertebra has a vertebral arch or neural arch, which extends dorsally around the spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001670", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.270", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "tiny neural arches present in Hagfish (which lack a true vertebraal column)." xsd:string property_value: UBPROP:0000011 "The neural arch can be a replacement ossification of the basidorsal cartilage or can form directly in membrane bone" xsd:string [Term] id: UBERON:0003862 name: pedal digit 4 phalanx namespace: uberon def: "A phalanx that is part of a foot digit 4 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "digit long bone of foot digit 4" EXACT [OBOL:automatic] synonym: "foot digit 4 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 4 long bone of digit" EXACT [OBOL:automatic] synonym: "foot digit 4 phalanx" EXACT [MA:0001384] synonym: "foot digit 4 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "fourth toe phalanx" EXACT [FMA:32901] synonym: "hind limb digit 4 phalanx" EXACT [OBOL:accepted] synonym: "long bone of digit of foot digit 4" EXACT [OBOL:automatic] synonym: "pedal digit IV phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "phalanx of fourth toe" EXACT [FMA:32901] xref: EMAPA:19130 xref: FMA:32901 xref: MA:0001384 xref: NCIT:C52781 xref: SCTID:361804008 xref: UMLS:C1708086 {source="ncithesaurus:Foot_Digit_4_Phalanx"} is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0015034 ! pedal digit 4 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: develops_from UBERON:0010683 ! pedal digit 4 phalanx cartilage element [Term] id: UBERON:0003863 name: pedal digit 5 phalanx namespace: uberon def: "A phalanx that is part of a foot digit 5 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "digit long bone of foot digit 5" EXACT [OBOL:automatic] synonym: "foot digit 5 digit long bone" EXACT [OBOL:automatic] synonym: "foot digit 5 long bone of digit" EXACT [OBOL:automatic] synonym: "foot digit 5 phalanx" EXACT [MA:0001385] synonym: "foot digit 5 phalanx" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 phalanx" EXACT [OBOL:accepted] synonym: "little toe phalanx" EXACT [FMA:32902] synonym: "long bone of digit of foot digit 5" EXACT [OBOL:automatic] synonym: "pedal digit V phalanx" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "phalanx of fifth digit of foot" EXACT [FMA:32902] synonym: "phalanx of fifth toe" EXACT [FMA:32902] synonym: "phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "phalanx of little toe" EXACT [FMA:32902] xref: EMAPA:19132 xref: FMA:32902 xref: MA:0001385 xref: NCIT:C52782 xref: SCTID:361806005 xref: UMLS:C1708088 {source="ncithesaurus:Foot_Digit_5_Phalanx"} is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0015035 ! pedal digit 5 phalanx endochondral element intersection_of: UBERON:0003221 ! phalanx intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: develops_from UBERON:0010684 ! pedal digit 5 phalanx cartilage element [Term] id: UBERON:0003864 name: middle phalanx of manus namespace: uberon def: "A middle phalanx that is part of a finger [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "hand middle phalanx" EXACT [MA:0001394] synonym: "middle manual phalanx" EXACT [] synonym: "middle phalanx of finger" EXACT [FMA:75817] synonym: "middle phalanx of hand" EXACT [MA:0001394] synonym: "middle phalanx of manual digit" EXACT [] synonym: "phalanx media manus" EXACT LATIN [FMA:75817, FMA:TA] xref: EMAPA:37306 {source="MA:th"} xref: FMA:75817 xref: MA:0001394 xref: NCIT:C12863 xref: SCTID:113223004 xref: SCTID:371230003 xref: UMLS:C0223828 {source="ncithesaurus:Middle_Phalanx_of_the_Hand"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0004301 ! middle phalanx intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: distally_connected_to UBERON:0001436 ! phalanx of manus relationship: proximally_connected_to UBERON:0001436 ! phalanx of manus [Term] id: UBERON:0003865 name: distal phalanx of manus namespace: uberon def: "A distal phalanx that is part of a finger [Automatically generated definition]." [OBOL:automatic] comment: This is typically proximally connected to the middle phalanx of manus, except in some cases such as the manual digit 1 (thumb) of many mammals such as humans, where it connects to the proximal phalanx. It always connects to some phalanx, by definition subset: pheno_slim synonym: "distal manual phalanx" EXACT [] synonym: "distal phalanx of finger" EXACT [FMA:75818] synonym: "distal phalanx of hand" EXACT [] synonym: "distal phalanx of manual digit" EXACT [] synonym: "hand distal phalanx" EXACT [MA:0001388] synonym: "phalanx distalis manus" EXACT LATIN [FMA:75818, FMA:TA] synonym: "terminal phalanx of hand" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "ungual phalanx of hand" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] xref: EMAPA:35393 xref: FMA:75818 xref: MA:0001388 xref: NCIT:C52784 xref: SCTID:182001007 xref: SCTID:361782004 xref: UMLS:C1269782 {source="ncithesaurus:Distal_Phalanx_of_Hand"} is_a: UBERON:0001436 ! phalanx of manus is_a: UBERON:0004300 ! distal phalanx intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0009552 ! distal segment of manual digit relationship: proximally_connected_to UBERON:0001436 ! phalanx of manus [Term] id: UBERON:0003866 name: middle phalanx of pes namespace: uberon def: "A middle phalanx that is part of a toe [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "foot middle phalanx" EXACT [MA:0001386] synonym: "middle pedal phalanx" EXACT [] synonym: "middle phalanx of foot" EXACT [] synonym: "middle phalanx of toe" EXACT [FMA:75829] synonym: "phalanx media pedis" EXACT LATIN [FMA:75829, FMA:TA] xref: EMAPA:37311 {source="MA:th"} xref: FMA:75829 xref: MA:0001386 xref: SCTID:83207005 is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0004301 ! middle phalanx intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0001466 ! pedal digit relationship: distally_connected_to UBERON:0001449 ! phalanx of pes relationship: proximally_connected_to UBERON:0001449 ! phalanx of pes [Term] id: UBERON:0003867 name: distal phalanx of pes namespace: uberon def: "A distal phalanx that is part of a pedal digit [Automatically generated definition]." [OBOL:automatic] comment: This is typically proximally connected to the middle phalanx of pes, except in some cases such as the pedal digit 1 (big toe) in many mammals such as humans, where it connects to the proximal phalanx. It always connects to some phalanx, by definition subset: pheno_slim synonym: "distal pedal phalanx" EXACT [] synonym: "distal phalanx of foot" EXACT [] synonym: "distal phalanx of toe" EXACT [FMA:75830] synonym: "foot distal phalanx" EXACT [MA:0001380] synonym: "phalanx distalis pedis" EXACT LATIN [FMA:75830, FMA:TA] synonym: "terminal phalanx of foot" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "terminal phalanx of hindlimb" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "ungual phalanx of foot" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] synonym: "ungual phalanx of hindlimb" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] xref: EMAPA:37310 {source="MA:th"} xref: FMA:75830 xref: MA:0001380 xref: NCIT:C52783 xref: SCTID:361797001 xref: UMLS:C0224026 {source="ncithesaurus:Distal_Phalanx_of_Foot"} is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0004300 ! distal phalanx intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0009553 ! distal segment of pedal digit relationship: proximally_connected_to UBERON:0001449 ! phalanx of pes [Term] id: UBERON:0003868 name: proximal phalanx of pes namespace: uberon def: "A proximal phalanx that is part of a pedal digit [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "foot proximal phalanx" EXACT [MA:0001387] synonym: "phalanx proximalis pedis" EXACT LATIN [FMA:75828, FMA:TA] synonym: "proximal pedal phalanx" EXACT [] synonym: "proximal phalanx of foot" EXACT [] synonym: "proximal phalanx of foot digit" EXACT [] synonym: "proximal phalanx of hind digit" EXACT [] synonym: "proximal phalanx of pes" EXACT [] synonym: "proximal phalanx of toe" EXACT [FMA:75828] xref: EMAPA:37312 {source="MA:th"} xref: FMA:75828 xref: MA:0001387 xref: NCIT:C52785 xref: SCTID:85533000 xref: UMLS:C0224020 {source="ncithesaurus:Proximal_Phalanx_of_Foot"} is_a: UBERON:0001449 ! phalanx of pes is_a: UBERON:0004302 ! proximal phalanx intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0001466 ! pedal digit relationship: proximally_connected_to UBERON:0001448 ! metatarsal bone [Term] id: UBERON:0003869 name: presumptive ganglion namespace: uberon def: "A presumptive structure that has the potential to develop into a ganglion." [OBOL:automatic] is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0000045 ! ganglion relationship: has_potential_to_develop_into UBERON:0000045 ! ganglion [Term] id: UBERON:0003885 name: mesometrium namespace: uberon def: "A mesentery that is part of a uterus [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "mesentery of uterus" RELATED [FMA:19816, http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/peritoneum.html, MA:0002931] xref: EMAPA:35562 xref: FMA:19816 xref: MA:0002931 xref: SCTID:250172001 xref: Wikipedia:Mesometrium is_a: UBERON:0001297 ! serosa of uterus is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0012332 ! broad ligament of uterus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003886 name: future coelemic cavity lumen namespace: uberon def: "An anatomical cavity that has the potential to develop into a coelemic cavity lumen." [OBOL:automatic] subset: grouping_class subset: non_informative synonym: "body cavity precursor" RELATED [] synonym: "future coelomic cavity lumen" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: has_potential_to_develop_into UBERON:0002323 ! coelemic cavity lumen relationship: existence_ends_during UBERON:0000111 ! organogenesis stage relationship: existence_starts_during UBERON:0000109 ! gastrula stage relationship: has_potential_to_develop_into UBERON:0002323 ! coelemic cavity lumen relationship: part_of UBERON:0000926 ! mesoderm [Term] id: UBERON:0003887 name: intraembryonic coelom namespace: uberon def: "The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom." [MGI:anna, MP:0012187] subset: pheno_slim synonym: "somatic coelom" EXACT [Wikipedia:Intraembryonic_coelom] xref: EHDAA:251 xref: EMAPA:16088 xref: NCIT:C34195 xref: UMLS:C1512940 {source="ncithesaurus:Intraembryonic_Coelom"} xref: VHOG:0000316 xref: Wikipedia:Intraembryonic_coelom is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0003081 {source="Wikipedia"} ! lateral plate mesoderm relationship: part_of UBERON:0011997 ! coelom property_value: editor_note "consider merging with coelom. TODO - add spatial relationships to halves of LPM. Note the OG places XAO and ZFA coelem terms here. editor note: TODO check ZFA, which appears to be a structure present in adults" xsd:string property_value: UBPROP:0000003 "(...) I regard it unlikely that coeloms of all bilaterian animals are comparable and evolved very early. Considering all these questions, few convincing characters concerning the evolution of body cavities remain to be named. (...) A segmental coelom appears to have evolved at least two times, in Annelida and in Myomerata (Acrania and Craniota).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000316", ontology="VHOG", source="ISBN:978-0198566694 Schmidt-Rhaesa A, The evolution of organ systems (2007) p.166", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003889 name: fallopian tube namespace: uberon def: "Initial section of the oviduct through which the ova pass from the ovary to the uterus." [http://orcid.org/0000-0002-6601-2165, MGI:smb, MP:0003574] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "fallopian tubes" RELATED [] synonym: "female paramesonephric duct" RELATED [EHDAA2:0000504] synonym: "mammalian oviduct" EXACT [https://sourceforge.net/p/geneontology/ontology-requests/8397/] synonym: "paramesonephric duct of female" RELATED [EMAPA:35660] synonym: "salpinges" BROAD PLURAL [] synonym: "salpinx" BROAD [] synonym: "tuba uterina" RELATED LATIN [Wikipedia:Fallopian_tube] synonym: "uterine tube (sensu Mammalia)" EXACT [] xref: CALOHA:TS-0732 xref: EHDAA2:0000504 xref: EMAPA:18984 xref: EMAPA:35660 xref: EV:0100112 xref: FMA:18245 xref: GAID:365 xref: galen:FallopianTube xref: MA:0000385 xref: MESH:D005187 xref: NCIT:C12403 xref: SCTID:181463001 xref: UMLS:C0015560 {source="ncithesaurus:Fallopian_Tube"} xref: Wikipedia:Fallopian_tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0013515 ! subdivision of oviduct is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0013515 ! subdivision of oviduct intersection_of: develops_from UBERON:0003890 ! Mullerian duct intersection_of: part_of UBERON:0000993 ! oviduct relationship: connects UBERON:0000995 ! uterus relationship: connects UBERON:0003984 ! uterine tube infundibulum relationship: develops_from UBERON:0003890 ! Mullerian duct relationship: in_lateral_side_of UBERON:0003975 {source="FMA-abduced-lr"} ! internal female genitalia relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0003975 ! internal female genitalia property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/68/Scheme_female_reproductive_system-en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "Homologous to appendix testis" xsd:string {source="Wikipedia:Talk:Fallopian_tube#Homology"} [Term] id: UBERON:0003890 name: Mullerian duct namespace: uberon alt_id: UBERON:0005318 def: "Paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin[WP]. develops either by lengthwise splitting of the archinephric duct (in chondrichthyans and some amphibians) or by a elongated invagination of the coelomic epithelium (other vertebrates) In males, the oviducts regress. The cranial end of the oviduct maintains an opening into the coelom (which primitively may have been the anteriormost coelomic funnels connecting the nephrocoel with the coelom). This opening is the ostium tubae[USM]." [GO:0061205, http://www.usm.maine.edu/bio/courses/bio205/bio205_26_sex.html, Wikipedia:Paramesonephric_duct] subset: pheno_slim synonym: "ductus paramesonephricus" EXACT [] synonym: "early paramesonephric duct" NARROW [EHDAA2:0004048] synonym: "Muellerian duct" EXACT [] synonym: "Müllerian duct" EXACT [] synonym: "paramesonephric duct" EXACT [EMAPA:27665] xref: AAO:0010141 xref: EHDAA2:0004048 xref: EMAPA:27665 xref: GAID:1309 xref: MESH:D009095 xref: NCIT:C13260 xref: RETIRED_EHDAA2:0001399 xref: SCTID:308802006 xref: UMLS:C0026732 {source="ncithesaurus:Mullerian_Duct"} xref: VHOG:0001199 xref: Wikipedia:Paramesonephric_duct xref: XAO:0000330 is_a: UBERON:0000025 ! tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0015212 ! lateral structure relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm relationship: in_lateral_side_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6d/Gray1109.png" xsd:anyURI property_value: UBPROP:0000001 "Either of the paired embryonic ducts developing into the uterine tubes, uterus, and vagina in the female and becoming largely obliterated in the male. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001199", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/paramesonephric+duct"} property_value: UBPROP:0000001 "Transient developmental organ which gives rise to oviducts in female (documented to persist in some male frogs).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010141", ontology="AAO", source="AAO:RED"} property_value: UBPROP:0000003 "In females, the archinephric (mesonephric) ducts tend to function only within the urinary systems. The muellerian duct arises embryologically next to the archinephric (wolffian) duct. In males, the muellerian duct regresses if it appears at all, but in females, the muellerian ducts become the oviducts of the reproductive system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001199", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.559", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "Sertoli cells secrete anti-Mullerian hormone (AMH) inducing the demise of this duct" xsd:string [Term] id: UBERON:0003891 name: stroma namespace: uberon def: "Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "stromal connective tissue" RELATED [] xref: FMA:81494 xref: NCIT:C67387 xref: UMLS:C0927195 {source="ncithesaurus:Stroma_Connective_Tissue"} is_a: UBERON:0000064 ! organ part relationship: composed_primarily_of UBERON:0002384 ! connective tissue relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: UBPROP:0000007 "stromal" xsd:string [Term] id: UBERON:0003894 name: liver primordium namespace: uberon def: "A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum." [ISBN:3211492755] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "embryological hepatic plate" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "hepatic plate" RELATED [EHDAA2:0000744] synonym: "liver bud" RELATED INCONSISTENT [XAO:0003266, ZFA:0000124] synonym: "liver endoderm" RELATED [EFO:0002577] synonym: "primordium of the liver" EXACT [ncithesaurus:Primordium_of_the_Liver] xref: AAO:0011058 xref: BTO:0003391 xref: EFO:0002577 xref: EFO:0003428 xref: EHDAA2:0000744 xref: EHDAA:973 xref: EMAPA:16847 xref: NCIT:C34277 xref: TAO:0000124 xref: UMLS:C0734013 {source="ncithesaurus:Hepatic_Cord"} xref: UMLS:C1514451 {source="ncithesaurus:Primordium_of_the_Liver"} xref: XAO:0003266 xref: ZFA:0000124 is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium is_a: UBERON:0001048 {source="XAO"} ! primordium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0009497 ! epithelium of foregut-midgut junction intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0002107 ! liver relationship: develops_from UBERON:0001041 {notes="ventral foregut endoderm", source="Zaret 1996"} ! foregut relationship: has_potential_to_develop_into UBERON:0002107 ! liver relationship: part_of UBERON:0009550 {source="EHDAA2"} ! endoderm of foregut-midgut junction property_value: editor_note "consider adding further subdivisions of the endoderm, e.g. ventral foregut. Note we place two EFO classes here, it's not clear how they differ" xsd:string [Term] id: UBERON:0003897 name: axial muscle namespace: uberon def: "One of the skeletal muscles of the head and neck, spine, and ribs." [HP:0003327] subset: pheno_slim xref: EHDAA:5982 xref: EMAPA:18167 xref: MA:0003153 xref: RETIRED_EHDAA2:0000160 xref: TAO:0001954 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to_part_of UBERON:0005944 ! axial skeleton plus cranial skeleton intersection_of: part_of UBERON:0013701 ! main body axis relationship: attaches_to_part_of UBERON:0005944 ! axial skeleton plus cranial skeleton relationship: part_of UBERON:0013700 ! axial musculature [Term] id: UBERON:0003898 name: skeletal muscle tissue of trunk namespace: uberon def: "A portion of skeletal muscle tissue in the trunk." [http://orcid.org/0000-0002-6601-2165] synonym: "skeletal muscle of torso" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of torso" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of trunk" EXACT [OBOL:automatic] synonym: "torso skeletal muscle" EXACT [OBOL:automatic] synonym: "torso skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "trunk skeletal muscle" EXACT [OBOL:automatic] synonym: "trunk skeletal muscle tissue" EXACT [OBOL:automatic] xref: SCTID:244848007 is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0004479 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! musculature of trunk relationship: part_of UBERON:0013700 ! axial musculature [Term] id: UBERON:0003902 name: retinal neural layer namespace: uberon def: "The part of the retina that contains neurons and photoreceptor cells[GO]." [GO:0003407] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "neural layer of retina" EXACT [FMA:58628] synonym: "neural retina" EXACT [XAO:0003216, ZFA:0000046] synonym: "neural retinal epithelium" RELATED [MA:000027] synonym: "neuroretina" EXACT [ZFA:0000046] synonym: "stratum nervosum (retina)" EXACT [FMA:58628] synonym: "stratum nervosum retinae" EXACT LATIN [FMA:58628, FMA:TA] xref: AAO:0011095 xref: BTO:0000929 xref: CALOHA:TS-0685 xref: EHDAA2:0001253 xref: EHDAA:4763 xref: EMAPA:17171 xref: EMAPA:18590 xref: FMA:58628 xref: MA:0000277 xref: NCIT:C33166 xref: TAO:0000046 xref: UMLS:C1518263 {source="ncithesaurus:Neural_Retina"} xref: VHOG:0000535 xref: XAO:0003216 xref: ZFA:0000046 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001781 ! layer of retina intersection_of: UBERON:0001781 ! layer of retina intersection_of: immediate_transformation_of UBERON:0005425 ! presumptive neural retina relationship: developmentally_induced_by UBERON:0005426 ! lens vesicle relationship: develops_from UBERON:0005425 ! presumptive neural retina relationship: has_part CL:0000210 ! photoreceptor cell relationship: immediate_transformation_of UBERON:0005425 {source="Bgee:AN"} ! presumptive neural retina property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000535", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003909 name: sinusoid namespace: uberon def: "Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]." [Wikipedia:Sinusoid_(blood_vessel)] subset: vertebrate_core synonym: "endothelium of irregular blood filled space" RELATED [] synonym: "sinusoidal blood vessel" EXACT [] synonym: "sinusoidal blood vessel endothelium" EXACT [ZFA:0005261] synonym: "sinusoidal capillary" RELATED [http://www.medilexicon.com/medicaldictionary.php?t=13986] synonym: "sinusoidal endothelium" RELATED [] xref: FMA:63131 xref: SCTID:340163004 xref: TAO:0005261 xref: Wikipedia:Sinusoid_(blood_vessel) xref: ZFA:0005261 is_a: UBERON:2005260 {source="Wikipedia", source="ZFA"} ! fenestrated capillary property_value: UBPROP:0000001 "Fenestrated blood vessel endothelium with pores that are large enough for blood cells to pass. The basal lamina and gap junctions may be discontinuous.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005261", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000007 "sinusoidal" xsd:string property_value: UBPROP:0000012 "some sources give discontinuous capillary as synonym but this may be a subtype - see FMA:63198 discontinuous sinusoid (undefined)." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0003913 name: tooth-like structure namespace: uberon def: "Hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food." [http://orcid.org/0000-0002-6601-2165] comment: see dermal denticle subset: grouping_class synonym: "tooth-like organ" EXACT [http://orcid.org/0000-0002-6601-2165] xref: HAO:0001019 is_a: UBERON:0004765 ! skeletal element relationship: capable_of_part_of GO:0071626 ! mastication relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: UBERON:0003914 name: epithelial tube namespace: uberon def: "Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." [GO:0060562, PMID:12526790] synonym: "epithelial or endothelial tube" EXACT [] xref: AEO:0000114 xref: EHDAA2:0003114 xref: FBbt:00007474 is_a: UBERON:0000025 ! tube is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: has_quality PATO:0002299 ! tubular property_value: IAO:0000232 "contrast with a multi-tissue tube, which has as parts both epithelium, connective tissue, possibly muscle layers" xsd:string [Term] id: UBERON:0003915 name: endothelial tube namespace: uberon def: "Any endothelium that has the quality of being cylindrical [Automatically generated definition]." [OBOL:automatic] is_a: UBERON:0001986 ! endothelium is_a: UBERON:0003914 ! epithelial tube intersection_of: UBERON:0001986 ! endothelium intersection_of: has_quality PATO:0002299 ! tubular [Term] id: UBERON:0003918 name: kidney mesenchyme namespace: uberon def: "Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]." [GO:0072074] subset: pheno_slim synonym: "mesenchyme of kidney" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: has_potential_to_develop_into UBERON:0002113 ! kidney relationship: has_potential_to_develop_into UBERON:0002113 ! kidney property_value: editor_note "check this" xsd:string [Term] id: UBERON:0003920 name: venous blood vessel namespace: uberon def: "A blood vessel that carries blood from the capillaries toward the heart." [http://www.thefreedictionary.com/venous+blood+vessel] comment: Compare to: vein synonym: "segment of venous tree organ" EXACT [FMA:86188] synonym: "venous tree organ segment" EXACT [FMA:86188] xref: EMAPA:35932 xref: FMA:86188 xref: MA:0000066 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004582 ! venous system relationship: part_of UBERON:0004582 ! venous system [Term] id: UBERON:0003921 name: pancreas primordium namespace: uberon def: "Embryonic structure that develops into pancreatic bud." [Wikipedia:Pancreas#Embryological_development] subset: efo_slim subset: vertebrate_core synonym: "pancreatic anlage" RELATED [ZFA:0000254] synonym: "pancreatic endoderm" RELATED [EFO:0002579] synonym: "pancreatic primordium" EXACT [] synonym: "primordial pancreas" RELATED [FMA:79792] xref: EFO:0002579 xref: EFO:0003434 xref: EHDAA2:0001382 xref: EHDAA:2163 xref: EMAPA:17066 xref: FMA:79792 xref: TAO:0000254 xref: XAO:0001101 xref: ZFA:0000254 is_a: UBERON:0001048 ! primordium is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0001264 ! pancreas relationship: develops_from UBERON:0000925 {source="Wikipedia"} ! endoderm relationship: has_potential_to_develop_into UBERON:0001264 ! pancreas relationship: part_of UBERON:0007026 ! presumptive gut property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI property_value: UBPROP:0000012 "in EHDAA2 this has dorsal and ventral primordia as parts. the buds are part of the primordium, with the ducts developing from the buds; only parenchyma and ducts have contribution from buds" xsd:string {external_ontology="EHDAA2"} property_value: UBPROP:0000013 "revisit after standardizing terms 'primordium', 'anlagen', 'bud'" xsd:string [Term] id: UBERON:0003922 name: pancreatic epithelial bud namespace: uberon def: "The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]." [PMID:16417468, Wikipedia:Pancreatic_bud] subset: efo_slim synonym: "pancreas epithelium" RELATED [EMAPA:35645] synonym: "pancreatic anlage" RELATED [] synonym: "pancreatic bud" EXACT [ZFA:0001390] synonym: "pancreatic buds" EXACT PLURAL [TAO:0001390] xref: EFO:0003470 xref: EMAPA:35645 xref: NCIT:C34242 xref: SCTID:360398004 xref: TAO:0001390 xref: UMLS:C1283285 {source="ncithesaurus:Pancreatic_Bud"} xref: Wikipedia:Pancreatic_bud xref: ZFA:0001390 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac relationship: develops_from UBERON:0001041 {source="Wikipedia:Pancreas#Embryological_development"} ! foregut relationship: develops_from UBERON:0001555 ! digestive tract relationship: develops_from UBERON:0002114 {exception="zebrafish", source="Wikipedia:Pancreatic_bud"} ! duodenum relationship: develops_from UBERON:0009497 {source="EHDAA2-inferred"} ! epithelium of foregut-midgut junction relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/49/Suckale08FBS_fig1_pancreas_development.jpeg" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI [Term] id: UBERON:0003923 name: dorsal pancreatic bud namespace: uberon def: "Pancreatic bud that gives rise to the accessory pancreatic duct." [Wikipedia:Pancreatic_bud] subset: efo_slim subset: vertebrate_core synonym: "dorsal pancreas anlage" RELATED [] synonym: "dorsal pancreatic anlage" RELATED [] synonym: "pancreas dorsal primordium duct bud" EXACT [EHDAA2:0001385] synonym: "pancreas primordium dorsal bud" EXACT [] synonym: "posterior pancreatic anlage" RELATED [] synonym: "posterior pancreatic bud" RELATED [] synonym: "primary pancreatic bud" EXACT [XAO:0000467] xref: AAO:0011031 xref: EFO:0003465 xref: EHDAA2:0001385 xref: EMAPA:17067 xref: SCTID:361435005 xref: TAO:0001370 xref: VHOG:0001428 xref: Wikipedia:Pancreatic_bud xref: XAO:0000467 xref: ZFA:0001370 is_a: UBERON:0003922 ! pancreatic epithelial bud relationship: developmentally_induced_by UBERON:0002328 {gci_relation="part_of", gci_filler="NCBITaxon:10088", source="PMID:16417468"} ! notochord relationship: developmentally_induced_by UBERON:0005805 {gci_relation="part_of", gci_filler="NCBITaxon:10088", source="PMID:16417468"} ! dorsal aorta relationship: develops_from UBERON:0001045 {source="XAO"} ! midgut relationship: part_of UBERON:0010375 {source="EHDAA2"} ! pancreas dorsal primordium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI property_value: UBPROP:0000001 "The pancreatic bud that gives rise to the accessory pancreatic duct.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011031", ontology="AAO", source="XAO:curator"} property_value: UBPROP:0000003 "In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001428", ontology="VHOG", source="DOI:10.1016/S0012-1606(03)00308-7 Field HA, Dong PD, Beis D, Stainier DY, Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology (2003), DOI:10.2337/diabetes.49.2.225 Polak M, Bouchareb-Banaei L, Scharfmann R, Czernichow P, Early pattern of differentiation in the human pancreas. Diabetes (2000)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0003924 name: ventral pancreatic bud namespace: uberon def: "Pancreatic bud that gives rise to the major pancreatic duct." [Wikipedia:Pancreatic_bud] subset: efo_slim subset: vertebrate_core synonym: "anterior pancreatic anlage" RELATED [] synonym: "anterior pancreatic bud" RELATED [] synonym: "pancreas primordium ventral bud" EXACT [] synonym: "pancreas ventral primordium duct bud" EXACT [EHDAA2:0001389] synonym: "ventral pancreas anlage" RELATED [] synonym: "ventral pancreatic anlage" RELATED [] xref: AAO:0011111 xref: EFO:0003464 xref: EHDAA2:0001389 xref: EMAPA:17256 xref: SCTID:361437002 xref: TAO:0001369 xref: VHOG:0001429 xref: Wikipedia:Pancreatic_bud xref: XAO:0001103 xref: ZFA:0001369 is_a: UBERON:0003922 ! pancreatic epithelial bud relationship: develops_from UBERON:0008835 {source="PMID:16417468", source="WP"} ! hepatic diverticulum relationship: part_of UBERON:0010376 {source="EHDAA2"} ! pancreas ventral primordium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/db/Gray982.png" xsd:anyURI property_value: UBPROP:0000003 "In chick, Xenopus laevis, and the teleost fish Medaka, the pancreas develops from three buds that emerge from the gut tube, two from its ventral aspect, and one from its dorsal aspect. In mouse, although there are initially three buds that arise from the gut tube at the point of contact between the endoderm and the vasculature, the pancreas develops from only two of these buds, one dorsal and one ventral. (...) In this study, we use a transgenic zebrafish line (...). We provide evidence for the existence of two distinct pancreatic anlagen - a ventral anterior bud and a dorsal posterior bud - that join to form the definitive pancreas (reference 1); The pancreas develops from the fusion of distinct endoderm-derived dorsal and ventral diverticula. In humans, by day 35 of development, the ventral pancreatic bud begins to migrate backwards and comes into contact and eventually fuses with the dorsal pancreatic bud during the sixth week of development (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001429", ontology="VHOG", source="DOI:10.1016/S0012-1606(03)00308-7 Field HA, Dong PD, Beis D, Stainier DY, Formation of the digestive system in zebrafish. II. Pancreas morphogenesis. Developmental Biology (2003), DOI:10.2337/diabetes.49.2.225 Polak M, Bouchareb-Banaei L, Scharfmann R, Czernichow P, Early pattern of differentiation in the human pancreas. Diabetes (2000)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "the ventral pancreas and liver are derived from a common precursor cell population[PMID:16417468]. TODO - add this relationship." xsd:string property_value: UBPROP:0000011 "The ventral pancreatic bud becomes the head and uncinate process, and comes from the hepatic diverticulum[WP]" xsd:string [Term] id: UBERON:0003928 name: digestive system duct namespace: uberon def: "A duct that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "duct of digestive system" EXACT [OBOL:automatic] synonym: "duct of gastrointestinal system" EXACT [OBOL:automatic] synonym: "gastrointestinal system duct" EXACT [OBOL:automatic] xref: TAO:0005162 xref: ZFA:0005162 is_a: UBERON:0000058 ! duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0001007 ! digestive system [Term] id: UBERON:0003929 name: digestive tract epithelium namespace: uberon def: "An epithelium that lines the lumen of the digestive tract." [http://orcid.org/0000-0002-6601-2165] synonym: "alimentary tract epithelium" RELATED [OBOL:automatic] synonym: "digestive tract epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelial tissue of digestive tract" EXACT [OBOL:automatic] synonym: "epithelial tissue of gut" EXACT [OBOL:automatic] synonym: "epithelium of digestive tract" EXACT [OBOL:automatic] synonym: "epithelium of gut" EXACT [OBOL:automatic] synonym: "gastrodermis" EXACT SENSU [https://orcid.org/0000-0003-3308-6245, NCBITaxon:6073] synonym: "gut epithelial tissue" EXACT [OBOL:automatic] synonym: "gut epithelium" EXACT [EHDAA2:0004567, MA:0003201, ZFA:0005123] xref: BTO:0000956 xref: EHDAA2:0004567 xref: EMAPA:32928 xref: FBbt:00047143 xref: MA:0003201 xref: NCIT:C12963 xref: TAO:0005123 xref: UMLS:C0836205 {source="ncithesaurus:Gut_Epithelium"} xref: XAO:0003200 xref: ZFA:0005123 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract property_value: UBPROP:0000001 "Epithelium lining the lumen of the gut.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005123", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000008 "" xsd:string [Term] id: UBERON:0003932 name: cartilage element of chondrocranium namespace: uberon def: "A cartilage element of chondrocranium. Example: neurocranial trabecula." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "cartilage of chondrocranium" EXACT [OBOL:accepted] synonym: "cartilaginous element of chondrocranium" EXACT [OBOL:accepted] synonym: "chondrocranium cartilage" EXACT [ZFA:0001461] synonym: "neurocranium cartilage" EXACT [ZFA:0001461] xref: EFO:0003690 xref: TAO:0001461 xref: ZFA:0001461 is_a: UBERON:0003933 ! cranial cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0002241 ! chondrocranium relationship: part_of UBERON:0002241 ! chondrocranium [Term] id: UBERON:0003933 name: cranial cartilage namespace: uberon def: "A cartilage element that is part of the cranial skeleton." [https://orcid.org/0000-0002-6601-2165, ZFA:0001458] synonym: "cartilage of cranium" EXACT [OBOL:automatic] synonym: "cranial cartilages" RELATED PLURAL [ZFA:0001458] synonym: "cranium cartilage" EXACT [OBOL:automatic] xref: TAO:0001458 xref: ZFA:0001458 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0010323 ! cranial skeletal system relationship: part_of UBERON:0010323 ! cranial skeletal system property_value: UBPROP:0000001 "Cartilage which is part of the cranium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001458", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0003937 name: reproductive gland namespace: uberon def: "Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction." [MP:0000653] subset: organ_slim subset: pheno_slim synonym: "genitalia gland" EXACT [OBOL:automatic] synonym: "gland of genitalia" EXACT [MP:0000653] synonym: "gland of reproductive system" EXACT [OBOL:automatic] synonym: "reproductive gland" EXACT [MA:0001751] synonym: "reproductive system gland" EXACT [OBOL:automatic] synonym: "sex gland" EXACT [MP:0000653] xref: MA:0001751 is_a: UBERON:0002530 ! gland is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000990 ! reproductive system [Term] id: UBERON:0003942 name: somatosensory system namespace: uberon alt_id: UBERON:0014511 def: "The sensory system for the sense of touch and pain." [NLXANAT:090818] subset: pheno_slim synonym: "somatic sensory system" EXACT [] synonym: "system for detection of somatic senses" EXACT [] xref: EMAPA:37954 {source="MA:th"} xref: neuronames:2887 xref: NLXANAT:090818 xref: Wikipedia:Somatosensory_system is_a: UBERON:0001032 ! sensory system relationship: capable_of_part_of GO:0019233 ! sensory perception of pain relationship: capable_of_part_of GO:0050975 ! sensory perception of touch property_value: UBPROP:0000001 "The neural tissue involved in the transmission of sensory signals" xsd:string {source="MP:0000959"} property_value: UBPROP:0000012 "MP defines this in a may more appropriate to somatosensory cortex" xsd:string {external_ontology="MP"} [Term] id: UBERON:0003946 name: placenta labyrinth namespace: uberon def: "The placental layers where embryonic blood vessels are surrounded by trophoblast cells and maternal blood." [MP:0001716] subset: pheno_slim synonym: "labyrinthine layer" EXACT [GO:0060713] synonym: "labyrinthine layer of placenta" EXACT [GO:0060713] synonym: "placental labyrinth" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: contributes_to_morphology_of UBERON:0001987 ! placenta relationship: part_of UBERON:0001987 ! placenta property_value: RO:0002161 NCBITaxon:9606 {source="http://placentation.ucsd.edu"} property_value: seeAlso "http://placentation.ucsd.edu/placenta.html" xsd:anyURI property_value: UBPROP:0000008 "Mouse-human differences: The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively ... The mouse placental labyrinth is composed of an intricate network of maternal blood spaces and embryonal blood vessels. Maternal and embryonal blood is separated by a placental barrier that consists of four cellular layers: layer I trophoblasts line the maternal lacunae, trophoblasts in layers II and III form syncytial-like layers, and endothelial cells line the embryonic vessels[DOI: 10.1073/pnas.96.14.8138 ]" xsd:string [Term] id: UBERON:0003952 name: anterior stroma of cornea namespace: uberon def: "The anterior segment of the lamellated connective tissue layer of the cornea." [MP:0003093] subset: human_reference_atlas subset: pheno_slim synonym: "anterior stroma" BROAD [MP:0003093] synonym: "cornea anterior stroma" EXACT [MP:0003093] xref: EMAPA:37414 {source="MA:th"} is_a: UBERON:0003566 ! head connective tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: in_anterior_side_of UBERON:0001777 ! substantia propria of cornea disjoint_from: UBERON:0003953 {source="lexical"} ! posterior stroma of cornea relationship: contributes_to_morphology_of UBERON:0001777 ! substantia propria of cornea relationship: in_anterior_side_of UBERON:0001777 ! substantia propria of cornea relationship: part_of UBERON:0001777 ! substantia propria of cornea property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0003953 name: posterior stroma of cornea namespace: uberon def: "The posterior segment of the lamellated connective tissue layer of the cornea." [MP:0003094] subset: pheno_slim synonym: "cornea posterior stroma" EXACT [MP:0003094] synonym: "posterior stroma" BROAD [MP:0003094] xref: EMAPA:37415 {source="MA:th"} is_a: UBERON:0003566 ! head connective tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002384 ! connective tissue intersection_of: in_posterior_side_of UBERON:0001777 ! substantia propria of cornea relationship: contributes_to_morphology_of UBERON:0001777 ! substantia propria of cornea relationship: in_posterior_side_of UBERON:0001777 ! substantia propria of cornea relationship: part_of UBERON:0001777 ! substantia propria of cornea [Term] id: UBERON:0003955 name: molar crown namespace: uberon def: "The part of a molar that is covered by enamel." [MP:0003932] subset: pheno_slim synonym: "crown of molar tooth" EXACT [FMA:85301] synonym: "molar tooth crown" EXACT [FMA:85301] synonym: "molar tooth tooth crown" EXACT [OBOL:automatic] synonym: "tooth crown of molar tooth" EXACT [OBOL:automatic] xref: EMAPA:37910 {source="MA:th"} xref: FMA:85301 is_a: UBERON:0003675 ! tooth crown intersection_of: UBERON:0003675 ! tooth crown intersection_of: part_of UBERON:0003655 ! molar tooth relationship: contributes_to_morphology_of UBERON:0003655 ! molar tooth relationship: part_of UBERON:0003655 ! molar tooth [Term] id: UBERON:0003959 name: rete testis namespace: uberon def: "An anastomosing network of delicate tubules located in the hilum of the testicle (mediastinum testis) that carries sperm from the seminiferous tubules to the vasa efferentia[WP]." [MP:0006416, Wikipedia:Rete_testis] subset: pheno_slim synonym: "Haller's rete" EXACT [FMA:19834] xref: EMAPA:18332 xref: FMA:19834 xref: GAID:399 xref: MA:0003013 xref: MESH:D012152 xref: NCIT:C33467 xref: SCTID:279617009 xref: UMLS:C0035278 {source="ncithesaurus:Rete_Testis"} xref: Wikipedia:Rete_testis is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0001343 ! seminiferous tubule of testis relationship: channels_into UBERON:0006946 ! efferent duct relationship: develops_from UBERON:0005297 {source="Wikipedia"} ! testis sex cord relationship: part_of UBERON:0005051 ! mediastinum testis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg" xsd:anyURI property_value: editor_note "add more specific classification e.g. anastomosing network - consider FMA:3726" xsd:string [Term] id: UBERON:0003967 name: cutaneous elastic tissue namespace: uberon def: "The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity." [MP:0008418] subset: pheno_slim synonym: "cutaneous elastic fiber" NARROW [MP:0008418] synonym: "dermal elastic fiber" NARROW [MP:0008418] xref: EMAPA:37841 {source="MA:th"} is_a: UBERON:0002521 ! elastic tissue is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0002521 ! elastic tissue intersection_of: part_of UBERON:0000014 ! zone of skin relationship: contributes_to_morphology_of UBERON:0000014 ! zone of skin relationship: part_of UBERON:0000014 ! zone of skin [Term] id: UBERON:0003970 name: placental labyrinth vasculature namespace: uberon def: "Blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate." [MP:0008803] subset: pheno_slim synonym: "placental labyrinth vascular network" EXACT [] synonym: "placental vasculature" RELATED [OBOL:automatic] synonym: "vasculature of placenta labyrinth" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0003946 ! placenta labyrinth relationship: part_of UBERON:0003946 ! placenta labyrinth [Term] id: UBERON:0003975 name: internal female genitalia namespace: uberon def: "The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina." [MP:0009209] comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547 subset: organ_slim subset: pheno_slim synonym: "female internal genitalia" EXACT [FMA:45654] synonym: "internal female genital organ" EXACT [BTO:0003099] synonym: "internal genitalia of female reproductive system" EXACT [OBOL:automatic] synonym: "organa genitalia feminina interna" RELATED [BTO:0003099] xref: BTO:0003099 xref: FMA:45654 xref: SCTID:303518005 is_a: UBERON:0003134 ! female reproductive organ is_a: UBERON:0004175 ! internal genitalia intersection_of: UBERON:0004175 ! internal genitalia intersection_of: part_of UBERON:0000474 ! female reproductive system [Term] id: UBERON:0003978 name: valve namespace: uberon subset: grouping_class synonym: "anatomical valve" EXACT [FMA:67611] xref: EHDAA2:0004046 xref: EHDAA:1892 xref: EHDAA:4406 xref: FMA:67611 xref: galen:Valve is_a: UBERON:0000064 ! organ part relationship: capable_of GO:0065008 ! regulation of biological quality property_value: UBPROP:0000007 "valvular" xsd:string [Term] id: UBERON:0003983 name: conus arteriosus namespace: uberon def: "A conical pouch formed from the upper and left angle of the right ventricle in the chordate heart, from which the pulmonary artery arises[WP]. the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminates in the pulmonary trunk[MP]." [MP:0009464, Wikipedia:Conus_arteriosus] xref: AAO:0010250 xref: Wikipedia:Conus_arteriosus is_a: UBERON:0004151 ! cardiac chamber relationship: part_of UBERON:0002080 ! heart right ventricle property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/46/Gray492.png" xsd:anyURI property_value: UBPROP:0000001 "Receives blood from the left atrium and becomes the median truncus arteriosus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010250", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000008 "Kardong says absent in adult tetrapods, check AAO" xsd:string property_value: UBPROP:0000013 "we use the term CA for the anterior chamber if it is composed of cardiac muscle, contractile, and contains conal valves internally" xsd:string {source="ISBN:0073040584"} [Term] id: UBERON:0003984 name: uterine tube infundibulum namespace: uberon def: "The funnel-like expansion of the abdominal extremity of the uterine tube[MP]." [MP:0009466, Wikipedia:Infundibulum_of_uterine_tube] subset: human_reference_atlas subset: pheno_slim synonym: "infundibulum" BROAD INCONSISTENT [] synonym: "infundibulum of fallopian tube" NARROW [FMA:18307] synonym: "infundibulum of oviduct" EXACT [FMA:18307] synonym: "infundibulum of uterine tube" EXACT [FMA:18307] synonym: "infundibulum tubae uterinae" RELATED LATIN [Wikipedia:Infundibulum_of_uterine_tube] xref: EMAPA:29897 xref: FMA:18307 xref: SCTID:362262001 xref: Wikipedia:Infundibulum_of_uterine_tube is_a: UBERON:0013515 {source="FMA"} ! subdivision of oviduct relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0003889 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="FMA"} ! fallopian tube property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/66/Illu_cervix.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:8782 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The third part of the uterine tube is the infundibulum. It terminates with the ostium of Fallopian tube, surrounded by fimbriae, one of which is attached to the ovary[Wikipedia:Infundibulum_of_uterine_tube]." xsd:string {source="Wikipedia:Infundibulum_of_uterine_tube"} property_value: UBPROP:0000008 "In mammals, the uterine tube infundibulum is part of the fallopian tube. In birds, where there is no fallopian tube, the uterine tube infundibulum is part of the oviduct." xsd:string {xref="https://orcid.org/0000-0002-2825-0621"} [Term] id: UBERON:0004015 name: embryonic-extraembryonic boundary namespace: uberon def: "The connection between the embryo proper and extraembryonic tissues." [MP:0003890] subset: pheno_slim is_a: UBERON:0000015 ! non-material anatomical boundary intersection_of: UBERON:0000015 ! non-material anatomical boundary intersection_of: adjacent_to UBERON:0000478 ! extraembryonic structure intersection_of: adjacent_to UBERON:0002050 ! embryonic structure relationship: adjacent_to UBERON:0000478 ! extraembryonic structure relationship: adjacent_to UBERON:0002050 ! embryonic structure [Term] id: UBERON:0004016 name: dermatome namespace: uberon def: "A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells." [AEO:0001017, AEO:JB] subset: pheno_slim synonym: "cutis plate" EXACT [Wikipedia:Cutis_plate] synonym: "dermatomal mesenchyme" EXACT [Wikipedia:Cutis_plate] synonym: "epimere mesoderm" RELATED [] synonym: "mesenchyma dermatomiale" RELATED LATIN [Wikipedia:Dermatomal_mesenchyme] xref: AAO:0011028 xref: AEO:0001017 xref: EHDAA2_RETIRED:0003428 xref: EHDAA:1719 xref: EHDAA:1725 xref: EHDAA:1731 xref: EHDAA:1737 xref: EMAPA:32838 xref: FMA:295656 xref: NCIT:C61572 xref: UMLS:C0180383 {source="ncithesaurus:Dermatome"} xref: Wikipedia:Dermatome_(embryology) xref: XAO:0000220 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0017650 {source="AEO"} ! developing mesenchymal structure relationship: develops_from UBERON:0004290 {source="EHDAA2-abduced"} ! dermomyotome property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f3/Gray64.png" xsd:anyURI property_value: UBPROP:0000013 "Not to be confused with 'dermatome segment of skin'." xsd:string [Term] id: UBERON:0004022 name: germinal neuroepithelium namespace: uberon def: "The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0004261] subset: pheno_slim synonym: "germinal neuroepithelial layer" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "germinal neuroepithelium" EXACT [NCBIBook:NBK10047] synonym: "original neural tube" EXACT [NCBIBook:NBK10047] is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0034706 {source="NCBIBook:NBK10047"} ! proliferating neuroepithelium disjoint_from: UBERON:0006934 ! sensory epithelium relationship: adjacent_to UBERON:0003842 ! neural tube lumen relationship: bounding_layer_of UBERON:0001049 ! neural tube relationship: part_of UBERON:0001049 ! neural tube property_value: UBPROP:0000011 "As the cells adjacent to the lumen continue to divide, the migrating cells form a second layer around the original neural tube. This layer becomes progressively thicker as more cells are added to it from the germinal neuroepithelium. This new layer is called the mantle (or intermediate) zone, and the germinal epithelium is now called the ventricular zone (and, later, the ependyma)[NCBIBook:NBK10047]" xsd:string [Term] id: UBERON:0004027 name: chorionic plate namespace: uberon def: "That portion of the chorionic wall in the region of its uterine attachment, which gives rise to chorionic villi; it consists of the mesoderm that lines the chorionic vesicle and, on the maternal side, of the trophoblast that lines the intervillous spaces; in the last half of gestation, the mesodermal connective tissue is largely replaced by fibrinoid material, and the amnionic membrane is adherent to the fetal side of the plate." [http://www.medilexicon.com/medicaldictionary.php?t=69523, MP:0004560] subset: human_reference_atlas subset: pheno_slim xref: BTO:0002879 xref: EMAPA:31872 xref: NCIT:C34123 xref: SCTID:256391000 xref: UMLS:C0230972 {source="ncithesaurus:Chorionic_Plate"} is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005292 ! extraembryonic tissue relationship: contributes_to_morphology_of UBERON:0003124 ! chorion membrane relationship: part_of UBERON:0003124 ! chorion membrane property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004035 name: cortical subplate namespace: uberon def: "The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate." [https://github.com/obophenotype/mouse-anatomy-ontology/issues/1, MP:0008440, Wikipedia:Subplate] subset: pheno_slim synonym: "cerebral cortex subplate" EXACT [EMAPA:32833] synonym: "SP" BROAD ABBREVIATION [BRAINSPAN:BRAINSPAN] synonym: "subplate" EXACT [] synonym: "subplate zone" EXACT [DHBA:10522] xref: DHBA:10522 xref: EMAPA:32703 xref: https://upload.wikimedia.org/wikipedia/commons/thumb/a/ac/Corticogenesis_in_a_wild-type_mouse_with_captions_in_english_copy.png/360px-Corticogenesis_in_a_wild-type_mouse_with_captions_in_english_copy.png xref: neuronames:3233 xref: PBA:294021932 xref: Wikipedia:Subplate is_a: UBERON:0014950 ! layer of developing cerebral cortex intersection_of: UBERON:0014950 ! layer of developing cerebral cortex intersection_of: adjacent_to UBERON:0004040 ! cortical intermediate zone intersection_of: adjacent_to UBERON:0005343 ! cortical plate relationship: adjacent_to UBERON:0004040 ! cortical intermediate zone relationship: adjacent_to UBERON:0005343 ! cortical plate relationship: develops_from UBERON:0034711 ! cortical preplate property_value: UBPROP:0000011 "The transient fetal subplate zone, together with the marginal zone and the cortical plate, represents the developmental anlage of the mammalian cerebral cortex. It serves as a waiting compartment for growing cortical afferents; its cells are involved in the establishment of pioneering cortical efferent projections and transient fetal circuitry, and apparently have a number of other developmental roles. The subplate zone is a phylogenetically recent structure and it is most developed in the human brain. Subplate neurons are among the first generated neurons in the mammalian cerebral cortex [1]. These neurons disappear during postnatal development and are important in establishing the correct wiring [2][3] and functional maturation [4] of the cerebral cortex. Subplate neurons appear to be selectively sensitive to injury (such as hypoxia) which in humans are associated with motor and cognitive defects" xsd:string {source="WP"} [Term] id: UBERON:0004040 name: cortical intermediate zone namespace: uberon def: "The region of the developing mammalian cortex that extends between the ventricular zone and the cortical plate (CP); normally, the IZ is a region of tangential migration of cells, and at midgestation, the lower part of the IZ develops into the subventricular zone." [MP:0008457] subset: pheno_slim synonym: "cerebral cortex mantle layer" RELATED [EMAPA:17545] synonym: "cerebral cortex mantle zone" RELATED [] synonym: "cortical mantle layer" RELATED [] synonym: "IZ" BROAD ABBREVIATION [BRAINSPAN:BRAINSPAN] xref: EMAPA:17545 xref: EMAPA:32712 is_a: UBERON:0014950 ! layer of developing cerebral cortex relationship: develops_from UBERON:0004061 ! neural tube mantle layer relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia [Term] id: UBERON:0004053 name: external male genitalia namespace: uberon def: "The external masculine genital organs, including the penis and scrotum." [MP:0009199] comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547 subset: organ_slim subset: pheno_slim synonym: "external male genital organ" EXACT [BTO:0003097] synonym: "male external genitalia" EXACT [FMA:45642] synonym: "organa genitalia masculina externa" RELATED [BTO:0003097] xref: BTO:0003097 xref: EMAPA:30977 xref: FMA:45642 xref: galen:MaleExternalGenitalia xref: SCTID:362264000 is_a: UBERON:0003135 ! male reproductive organ is_a: UBERON:0004176 ! external genitalia intersection_of: UBERON:0004176 ! external genitalia intersection_of: part_of UBERON:0000079 ! male reproductive system disjoint_from: UBERON:0005056 ! external female genitalia disjoint_from: UBERON:0009196 ! indifferent external genitalia relationship: contributes_to_morphology_of UBERON:0000079 ! male reproductive system [Term] id: UBERON:0004054 name: internal male genitalia namespace: uberon def: "The internal masculine genital organs, including the testes, epididymides, deferent ducts, seminal vesicles, prostate, ejaculatory ducts, and bulbourethral glands." [MP:0009205] comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547 subset: organ_slim subset: pheno_slim synonym: "internal male genital organ" EXACT [BTO:0003096] synonym: "male internal genitalia" EXACT [FMA:45655] synonym: "organa genitalia masculina interna" RELATED [BTO:0003096] xref: BTO:0003096 xref: FMA:45655 xref: SCTID:310536002 is_a: UBERON:0003135 ! male reproductive organ is_a: UBERON:0004175 ! internal genitalia intersection_of: UBERON:0004175 ! internal genitalia intersection_of: part_of UBERON:0000079 ! male reproductive system relationship: contributes_to_morphology_of UBERON:0000079 ! male reproductive system property_value: editor_note "consider splitting genitalia from genital organ" xsd:string [Term] id: UBERON:0004058 name: biliary ductule namespace: uberon def: "One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP]." [BTO:0002840, MP:0009494] subset: human_reference_atlas subset: pheno_slim synonym: "bile capillary" RELATED [BTO:0002840] synonym: "bile ductule" EXACT [BTO:0002840] synonym: "biliary ductule" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi] synonym: "biliary ductule" RELATED [BTO:0002840] synonym: "cholangiole" RELATED [BTO:0002840] synonym: "ductuli biliferi" EXACT [http://www.mondofacto.com/facts/dictionary?ductuli+biliferi] synonym: "terminal cholangiole" RELATED [http://orcid.org/0000-0002-6601-2165] xref: BTO:0002840 xref: EMAPA:37440 {source="MA:th"} xref: TAO:0005164 xref: ZFA:0005164 is_a: UBERON:0000025 ! tube is_a: UBERON:0004119 ! endoderm-derived structure relationship: adjacent_to UBERON:0001175 ! common hepatic duct relationship: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002394 {source="BTO"} ! bile duct property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "In ZFA, Digestive system duct that collects bile from the canaliculus and transports bile through the liver -- (check if the same) // The smallest and the most peripheral branches of the biliary tree consist of a portal part (portal ductule) and an intralobular part (intralobular ductule)" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0004060 name: neural tube ventricular layer namespace: uberon def: "The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009689] subset: pheno_slim synonym: "ependymal layer" BROAD [NCBIBook:NBK10047] synonym: "neural tube ependymal layer" EXACT [NCBIBook:NBK10047] synonym: "neural tube ependymal zone" NARROW [MP:0009689] synonym: "neural tube ventricular germinal zone" EXACT [NCBIBook:NBK10047] synonym: "neural tube ventricular zone" EXACT [MP:0009689] xref: EMAPA:17152 xref: EMAPA:35362 xref: EMAPA_RETIRED:16783 xref: MA:0003193 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0034706 {source="NCBIBook:NBK10047"} ! proliferating neuroepithelium relationship: adjacent_to UBERON:0003842 ! neural tube lumen relationship: develops_from UBERON:0004022 ! germinal neuroepithelium relationship: immediate_transformation_of UBERON:0004022 {source="NCBIBook:NBK10047"} ! germinal neuroepithelium relationship: part_of UBERON:0001049 ! neural tube property_value: editor_note "consider merging with 'ventricular zone'; note that the MA class probably does not belong here, as this is an embryonic structure" xsd:string property_value: UBPROP:0000001 "The layer of undifferentiated, proliferating cells that line the neural tube lumen" xsd:string {source="MP:0009689"} [Term] id: UBERON:0004061 name: neural tube mantle layer namespace: uberon def: "The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009690] subset: pheno_slim synonym: "future brain marginal layer" RELATED [EMAPA:35360] synonym: "neural tube intermediate zone" EXACT [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009690] xref: EMAPA:17148 xref: EMAPA:35360 xref: neuronames:1367 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0034707 {source="NCBIBook:NBK10047"} ! differentiating neuroepithelium relationship: adjacent_to UBERON:0004060 ! neural tube ventricular layer relationship: adjacent_to UBERON:0004062 ! neural tube marginal layer relationship: develops_from UBERON:0004022 {notes="by division", source="NCBIBook:NBK10047"} ! germinal neuroepithelium relationship: part_of UBERON:0001049 ! neural tube [Term] id: UBERON:0004062 name: neural tube marginal layer namespace: uberon def: "The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009691] subset: pheno_slim synonym: "brain marginal zone" RELATED [] synonym: "neural tube marginal zone" EXACT [MP:0009691] xref: EMAPA:17151 xref: neuronames:1368 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005162 ! multi cell part structure relationship: adjacent_to UBERON:0004061 ! neural tube mantle layer relationship: develops_from UBERON:0004061 {notes="forms from axons"} ! neural tube mantle layer relationship: part_of UBERON:0001049 ! neural tube [Term] id: UBERON:0004064 name: neural tube basal plate namespace: uberon def: "The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0009693, Wikipedia:Basal_plate_(neural_tube)] subset: efo_slim subset: pheno_slim synonym: "basal plate" EXACT [] synonym: "basal plate of neural tube" EXACT [Wikipedia:Basal_plate_(neural_tube)] synonym: "motor part of neural tube" RELATED [] synonym: "spinal cord basal plate" NARROW [MP:0009693] synonym: "ventral part of neural tube" RELATED [] xref: AAO:0010561 xref: EFO:0001904 xref: NCIT:C34111 xref: neuronames:1372 xref: UMLS:C1511061 {source="ncithesaurus:Basal_Plate"} xref: Wikipedia:Basal_plate_(neural_tube) is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: contributes_to_morphology_of UBERON:0004061 ! neural tube mantle layer relationship: developmentally_induced_by UBERON:0002328 {gene="Shh", source="Swenson"} ! notochord relationship: has_part CL:0000100 ! motor neuron relationship: part_of UBERON:0004061 ! neural tube mantle layer relationship: ventral_to UBERON:0005478 ! sulcus limitans of neural tube [Term] id: UBERON:0004066 name: frontonasal prominence namespace: uberon alt_id: UBERON:0006237 def: "The unpaired embryonic prominence that is formed by the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout." [MP:0009901] subset: pheno_slim synonym: "embryonic frontonasal prominence" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "forebrain prominence" RELATED [MP:0009901] synonym: "frontonasal mass" RELATED [MP:0009901] synonym: "frontonasal process" RELATED [MP:0009901] synonym: "prominentia frontonasalis" RELATED LATIN [Wikipedia:Frontonasal_prominence] xref: EHDAA2:0000578 xref: EHDAA:4778 xref: EMAPA:16681 xref: FMA:293101 xref: NCIT:C34182 xref: SCTID:361486000 xref: UMLS:C1517321 {source="ncithesaurus:Frontonasal_Prominence"} xref: VHOG:0001319 xref: Wikipedia:Frontonasal_prominence is_a: UBERON:0009292 ! embryonic nasal process relationship: intersects_midsagittal_plane_of UBERON:0000033 ! head property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/98/Gray44.png" xsd:anyURI [Term] id: UBERON:0004068 name: medial nasal prominence namespace: uberon def: "The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it." [MP:0009903, Wikipedia:Medial_nasal_prominence] subset: pheno_slim synonym: "medial nasal process" EXACT [EHDAA2:0001076] synonym: "medial nasal swelling" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "medial-nasal process" EXACT [EMAPA:16808] synonym: "nasomedial prominence" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "prominentia nasalis medialis" EXACT LATIN [Wikipedia:Medial_nasal_prominence] xref: EHDAA2:0001076 xref: EHDAA:4792 xref: EMAPA:16808 xref: FMA:295858 xref: SCTID:308877001 xref: VHOG:0000804 xref: Wikipedia:Medial_nasal_prominence is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0009292 ! embryonic nasal process relationship: develops_from UBERON:0004066 {source="Wikipedia"} ! frontonasal prominence relationship: in_lateral_side_of UBERON:0008816 ! embryonic head relationship: part_of UBERON:0004066 {source="EHDAA2"} ! frontonasal prominence relationship: part_of UBERON:0008816 ! embryonic head property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/85/Gray45.png" xsd:anyURI property_value: UBPROP:0000011 "Fusion of right and left medial nasal processes forms a primary palate rostrally and the nasal septum caudally. The incisive bone, including upper incisor teeth and the rostral up- per lip, are derived from the primary palate. The nasal septum consists of bone, cartilage, and a patch of soft tissue membrane that separates right & left halves of the nasal cavity." xsd:string [Term] id: UBERON:0004087 name: vena cava namespace: uberon def: "Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Venae_cavae] subset: pheno_slim synonym: "caval vein" RELATED [] synonym: "venae cavae" RELATED PLURAL [Wikipedia:Venae_cavae] xref: AAO:0010215 xref: BTO:0001438 xref: EMAPA:18415 xref: FMA:321896 xref: GAID:547 xref: MA:0000068 xref: MESH:D014684 xref: NCIT:C12817 xref: SCTID:244405007 xref: UMLS:C0042460 {source="ncithesaurus:Vena_Cava"} xref: Wikipedia:Venae_cavae is_a: UBERON:0003479 ! thoracic cavity vein is_a: UBERON:0013768 ! great vessel of heart property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/35/Relations_of_the_aorta,_trachea,_esophagus_and_other_heart_structures.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/7c/Heart_numlabels.png" xsd:anyURI [Term] id: UBERON:0004088 name: orbital region namespace: uberon def: "The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "content of orbital part of eye" EXACT [FMA:260119] synonym: "eye region" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ocular and peri-ocular region" RELATED [] synonym: "ocular region" RELATED [] synonym: "orbital content" RELATED [FMA:260119] synonym: "orbital part of eye" RELATED [FMA:72951] synonym: "orbital part of face" EXACT [http://orcid.org/0000-0002-6601-2165] xref: FMA:260119 is_a: UBERON:0001444 ! subdivision of head relationship: part_of UBERON:0001456 ! face property_value: editor_note "note the FMA class is more narrow though, and is more like eye + muscles + vasculature. The FMA also has FMA:72951 orbital part of eye" xsd:string property_value: UBPROP:0000012 "in HP covers eyelid, eyebrow." xsd:string {external_ontology="HP:0000284"} [Term] id: UBERON:0004089 name: midface namespace: uberon def: "The middle of the face including the nose and its associated bony structures[MW]." [HP:0000309, http://www.merriam-webster.com/medical/midface] subset: pheno_slim synonym: "lower face" RELATED [] synonym: "midface/lower face" RELATED [] synonym: "snout" RELATED SENSU [MA:0001910] xref: EMAPA:32806 xref: FMA:285406 xref: MA:0001910 is_a: UBERON:0001444 ! subdivision of head relationship: contributes_to_morphology_of UBERON:0001456 ! face relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of UBERON:0001456 ! face property_value: editor_note "this class is currently a union of the snout (e.g. in mouse), the midface and the lower face. Note that in MA, snout includes the whole jaw and should thus be more alike the lower face than the midface, so its placement here is not strictly accurate. In future we might introduce specific classes for each of these, and include the full parthood relationships. if this is done, then care should be taken to preserve inferences such as an abnormality of the lower face being an abnormality of the midface." xsd:string property_value: UBPROP:0000007 "midfacial" xsd:string [Term] id: UBERON:0004099 name: joint space of elbow namespace: uberon def: "Joint cavity shared by all the joints of the elbow. The elbow joint is a compound joint that actually comprises three separate joints: the joints connecting the upper and lower arm: 1) Articulatio humero-ulnaris and 2) Articulatio humero-radialis as well as the proximal joint connecting the forarm bones: 3) Articulatio radio-ulnaris proximalis. All three share a joint cavity which is highly sinuated/scalloped/coved. Joint spaces of the elbow summarizes the joint cavity shared by all three adjoining joints of the elbow joint." [HP:0003943] subset: pheno_slim synonym: "synovial cavity of elbow joint" EXACT [FMA:38911] xref: FMA:38911 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001490 ! elbow joint relationship: luminal_space_of UBERON:0001490 ! elbow joint relationship: part_of UBERON:0001490 ! elbow joint [Term] id: UBERON:0004100 name: renal collecting system namespace: uberon def: "The collecting duct system of the kidney consists of a series of tubules and ducts that connect the nephrons to the ureter. It participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and antidiuretic hormone." [HP:0004742, Wikipedia:Collecting_duct_system] subset: human_reference_atlas subset: pheno_slim synonym: "collecting duct system" EXACT [Wikipedia:Collecting_duct_system] synonym: "kidney collecting duct system" EXACT [Wikipedia:Collecting_duct_system] synonym: "tubulus renalis colligens" RELATED LATIN [Wikipedia:Collecting_duct_system] xref: FMA:265239 xref: SCTID:279371005 xref: Wikipedia:Collecting_duct_system is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0002113 ! kidney property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/0/02/Gray1128.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004103 name: alveolar ridge namespace: uberon def: "One of the two jaw ridges either on the roof of the mouth between the upper teeth and the hard palate or on the bottom of the mouth behind the lower teeth[WP]. The alveolar ridges contain the sockets (alveoli) of the teeth[HP]." [HP:0006477, Wikipedia:Alveolar_ridge] subset: pheno_slim synonym: "alveolar body" EXACT [MP:0004189] synonym: "alveolar bone" EXACT [MP:0004189] synonym: "alveolar margin" EXACT [] synonym: "alveolar process" EXACT [] synonym: "margo alveolaris" EXACT LATIN [] xref: BTO:0001383 xref: EMAPA:35118 xref: FMA:313923 xref: GAID:215 xref: MA:0003119 xref: MESH:D000539 xref: NCIT:C89749 xref: SCTID:245790000 xref: UMLS:C0447411 {source="ncithesaurus:Alveolar_Ridge"} xref: Wikipedia:Alveolar_ridge is_a: UBERON:0005913 ! zone of bone organ is_a: UBERON:0010313 ! neural crest-derived structure relationship: has_developmental_contribution_from UBERON:0008969 {source="PMID:19767574", source="Wikipedia"} ! dental follicle relationship: part_of UBERON:0001708 ! jaw skeleton property_value: UBPROP:0000012 "in BTO, this is part of an embryo" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0004111 name: anatomical conduit namespace: uberon def: "Any tube, opening or passage that connects two distinct anatomical spaces." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy synonym: "foramen" NARROW [EHDAA2:0003080] synonym: "foramina" NARROW PLURAL [https://orcid.org/0000-0002-6601-2165] synonym: "opening" RELATED [] synonym: "ostia" RELATED PLURAL [] synonym: "ostium" RELATED [] xref: AEO:0000080 xref: EHDAA2:0003080 xref: FMA:242873 xref: SCTID:346902003 xref: Wikipedia:Foramen is_a: UBERON:0010000 ! multicellular anatomical structure intersection_of: UBERON:0010000 ! multicellular anatomical structure intersection_of: conduit_for UBERON:0000061 ! anatomical structure intersection_of: has_part UBERON:0013686 ! anatomical conduit space relationship: conduit_for UBERON:0000061 ! anatomical structure relationship: connects UBERON:0000464 {cardinality="2"} ! anatomical space relationship: has_part UBERON:0013686 ! anatomical conduit space property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000012 "FMA has both conduit and conduit space. In EHDAA2 this is a surface feature" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004113 name: muscle of auditory ossicle namespace: uberon alt_id: UBERON:0004112 def: "A muscle of the tympanic cavity that attaches to an auditory ossicle." [http://orcid.org/0000-0002-6601-2165] synonym: "auditory ossicles muscle" EXACT [FMA:49026] synonym: "muscle of auditory ossicles" EXACT [FMA:49026] synonym: "muscle of middle ear" RELATED [] synonym: "muscle of tympanic cavity" EXACT [] synonym: "ossicular muscle" EXACT [FMA:49026] synonym: "tympanic cavity muscle" EXACT [MA:0000256] xref: EMAPA:37776 {source="MA:th"} xref: FMA:49026 xref: MA:0000256 xref: NCIT:C33148 xref: SCTID:244778009 xref: UMLS:C1513769 {source="ncithesaurus:Muscle_of_the_Tympanum"} xref: Wikipedia:Muscles_of_auditory_ossicles is_a: UBERON:0002376 {source="FMA"} ! cranial muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: attaches_to UBERON:0001686 ! auditory ossicle bone relationship: attaches_to UBERON:0001686 ! auditory ossicle bone relationship: located_in UBERON:0004114 ! tympanic cavity relationship: part_of UBERON:0001756 ! middle ear property_value: UBPROP:0000009 "attenuate low-frequency sounds, reduce masking of high-frequency sounds by low-frequency sounds, frequency-selection filter" xsd:string [Term] id: UBERON:0004114 name: tympanic cavity namespace: uberon def: "Small cavity surrounding the bones of the middle ear." [Wikipedia:Tympanic_cavity] synonym: "anatomical cavity of middle ear" EXACT [OBOL:automatic] synonym: "cavitas tympani" EXACT LATIN [Wikipedia:Tympanic_cavity] synonym: "cavitas tympanica" RELATED [BTO:0002098] synonym: "cavity of middle ear" EXACT [OBOL:automatic] synonym: "middle ear cavity" EXACT [OBOL:automatic] synonym: "middle-ear cavity" EXACT [OBOL:automatic] synonym: "tympanum" RELATED [BTO:0002098] xref: BTO:0002098 xref: EHDAA2:0004119 xref: EMAPA:37778 {source="MA:th"} xref: FMA:56461 xref: SCTID:362551002 xref: Wikipedia:Tympanic_cavity is_a: UBERON:0002553 ! anatomical cavity is_a: UBERON:0005082 ! tube lumen is_a: UBERON:0010064 {source="EHDAA2"} ! open anatomical space intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0001756 ! middle ear relationship: developmentally_replaces UBERON:0005625 {source="EHDAA2"} ! tubotympanic recess lumen relationship: luminal_space_of UBERON:0001756 ! middle ear relationship: part_of UBERON:0001756 ! middle ear relationship: surrounded_by UBERON:0010063 ! tympanic cavity epithelium relationship: surrounds UBERON:0001686 ! auditory ossicle bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/19/Gray923.png" xsd:anyURI [Term] id: UBERON:0004115 name: blood vessel of tympanic cavity namespace: uberon def: "A blood vessel that is part of a tympanic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical cavity of middle ear blood vessel" EXACT [OBOL:automatic] synonym: "blood vessel of anatomical cavity of middle ear" EXACT [OBOL:automatic] synonym: "blood vessel of cavity of middle ear" EXACT [OBOL:automatic] synonym: "blood vessel of middle ear anatomical cavity" EXACT [OBOL:automatic] synonym: "blood vessel of middle ear cavity" EXACT [OBOL:automatic] synonym: "cavity of middle ear blood vessel" EXACT [OBOL:automatic] synonym: "middle ear anatomical cavity blood vessel" EXACT [OBOL:automatic] synonym: "middle ear blood vessel" EXACT [] synonym: "middle ear cavity blood vessel" EXACT [OBOL:automatic] synonym: "tympanic cavity blood vessel" EXACT [] xref: EMAPA:37775 {source="MA:th"} xref: MA:0001219 is_a: UBERON:0003496 ! head blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: located_in UBERON:0004114 ! tympanic cavity relationship: located_in UBERON:0004114 ! tympanic cavity relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0004116 name: nerve of tympanic cavity namespace: uberon def: "A nerve that is part of a tympanic cavity [Automatically generated definition]." [OBOL:automatic] synonym: "anatomical cavity of middle ear nerve" EXACT [OBOL:automatic] synonym: "cavity of middle ear nerve" EXACT [OBOL:automatic] synonym: "middle ear anatomical cavity nerve" EXACT [OBOL:automatic] synonym: "middle ear cavity nerve" EXACT [OBOL:automatic] synonym: "nerve of anatomical cavity of middle ear" EXACT [OBOL:automatic] synonym: "nerve of cavity of middle ear" EXACT [OBOL:automatic] synonym: "nerve of middle ear anatomical cavity" EXACT [OBOL:automatic] synonym: "nerve of middle ear cavity" EXACT [OBOL:automatic] synonym: "tympanic cavity nerve" EXACT [] synonym: "tympanic cavity nerves" EXACT [MA:0001222] xref: EMAPA:37777 {source="MA:th"} xref: MA:0001222 is_a: UBERON:0011779 ! nerve of head region intersection_of: UBERON:0001021 ! nerve intersection_of: located_in UBERON:0004114 ! tympanic cavity relationship: located_in UBERON:0004114 ! tympanic cavity relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0004117 name: pharyngeal pouch namespace: uberon def: "An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches." [http://orcid.org/0000-0002-6601-2165, PMID:23020903, ZFA:0001106] comment: The pouches are polarized structures. For example, whereas the rostral half of each pouch expresses Bmp-7, the caudal half expresses FGF-8 and the dorsal aspect of each pouch is marked via its expression of Pax-1. each pouch has an individual sense of identity. Shh expression is a prominent early feature of the caudal endoderm of the second arch, and individual pouches mark the anterior limits of expression of Hox genes within the pharyngeal endoderm; Hox-a2 has a rostral boundary at the second pouch, Hox-a3 at the third pouch and Hox-a4 at the most caudal pouch[PMID:16313389] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "branchial pouch" EXACT [Wikipedia:Branchial_pouch] synonym: "pharyngeal pouches" RELATED [VHOG:0001203] synonym: "visceral pouch" EXACT SENSU [] synonym: "visceral pouches" RELATED [VHOG:0001203] xref: AAO:0011113 xref: EFO:0003627 xref: EHDAA:1086 xref: EHDAA:1669 xref: EHDAA:579 xref: EHDAA:617 xref: EMAPA:32752 xref: FMA:293063 xref: NCIT:C34252 xref: SCTID:34674002 xref: TAO:0001106 xref: UMLS:C0231067 {source="ncithesaurus:Pharyngeal_Pouch"} xref: VHOG:0001203 xref: Wikipedia:Pharyngeal_pouch_(embryology) xref: XAO:0000282 xref: ZFA:0001106 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0003258 ! endoderm of foregut is_a: UBERON:0005291 ! embryonic tissue relationship: develops_from UBERON:0007690 {source="EHDAA2", source="ZFA"} ! early pharyngeal endoderm relationship: only_in_taxon NCBITaxon:7711 {source="http://tolweb.org/Chordata/2499"} ! Chordata relationship: overlaps UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0008814 ! pharyngeal arch system property_value: UBPROP:0000001 "Outpocketings of pharyngeal endoderm that interdigitate with the neural crest derived pharyngeal arches. The pouches later fuse with the surface ectoderm to form the gill slits. Crump et al, 2004.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001106", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001203", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M, Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "EMAPA also includes a distinct pouch endoderm" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0004118 name: vasculature of iris namespace: uberon def: "A vasculature that is part of a iris [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "iris blood vessels" EXACT [ZFA:0005568] synonym: "iris vascular network" EXACT [OBOL:automatic] synonym: "iris vasculature" EXACT [] synonym: "vascular network of iris" EXACT [OBOL:automatic] xref: ZFA:0005568 is_a: UBERON:0002203 ! vasculature of eye intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001769 ! iris relationship: part_of UBERON:0001769 ! iris [Term] id: UBERON:0004119 name: endoderm-derived structure namespace: uberon def: "An anatomical structure that develops (entirely or partially) from the endoderm." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000925 ! endoderm relationship: develops_from UBERON:0000925 ! endoderm property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0004120 name: mesoderm-derived structure namespace: uberon def: "An anatomical structure that develops (entirely or partially) from the mesoderm." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "mesodermal derivative" EXACT [FBbt:00025998] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000926 ! mesoderm relationship: develops_from UBERON:0000926 ! mesoderm property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0004121 name: ectoderm-derived structure namespace: uberon def: "An anatomical structure that develops (entirely or partially) from the ectoderm." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "ectodermal deriviative" EXACT [FBbt:00025990] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0000924 ! ectoderm relationship: develops_from UBERON:0000924 ! ectoderm property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0004122 name: genitourinary system namespace: uberon def: "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction." [VHOG:0000286] subset: efo_slim subset: pheno_slim synonym: "genito-urinary system" RELATED [FMA:280610] synonym: "genitourinary tract" RELATED [] synonym: "GU tract" RELATED [] synonym: "UG tract" RELATED [] synonym: "urogenital system" EXACT [] synonym: "urogenital tract" RELATED [BTO:0003091] synonym: "Urogenitalsystem" RELATED [BTO:0003091] xref: AAO:0000624 xref: BILA:0000122 xref: BTO:0003091 xref: EFO:0003864 xref: EHDAA:1013 xref: EMAPA:16367 xref: EV:0100094 xref: FMA:280610 xref: GAID:362 xref: galen:GenitoUrinarySystem xref: MESH:D014566 xref: NCIT:C12810 xref: SCTID:278861008 xref: UMLS:C0042066 {source="ncithesaurus:Genitourinary_System"} xref: VHOG:0000286 xref: XAO:0000140 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: has_part UBERON:0000990 ! reproductive system intersection_of: has_part UBERON:0001008 ! renal system relationship: develops_from UBERON:0003064 {gci_relation="part_of", gci_filler="NCBITaxon:7742", source="AAO", source="https://github.com/geneontology/go-ontology/issues/16143"} ! intermediate mesoderm relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000990 ! reproductive system relationship: has_part UBERON:0001008 ! renal system property_value: UBPROP:0000001 "Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000624", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000002 "relationship type change: differentiates_from intermediate mesoderm (AAO:0010575) CHANGED TO: develops_from intermediate mesoderm (UBERON:0003064)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000624", ontology="AAO"} property_value: UBPROP:0000003 "Kidneys and gonads (of vertebrates) develop from adjacent tissues, and after the excretory or urinary ducts have developed, the reproductive system usually taps into them or their derivatives.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000286", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.633", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "genitourinary" xsd:string property_value: UBPROP:0000007 "urogenital" xsd:string [Term] id: UBERON:0004123 name: myocardial layer namespace: uberon def: "Any of the layers of the myocardium. Example: compact layer, trabecular layer." [http://orcid.org/0000-0002-6601-2165] subset: non_informative subset: pheno_slim synonym: "layer of myocardium" EXACT [] synonym: "myocardium layer" EXACT [] xref: EMAPA:37475 {source="MA:th"} xref: MA:0000080 is_a: UBERON:0005983 ! heart layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: layer_part_of UBERON:0002349 ! myocardium relationship: layer_part_of UBERON:0002349 ! myocardium relationship: part_of UBERON:0002349 ! myocardium [Term] id: UBERON:0004124 name: myocardium trabecular layer namespace: uberon def: "The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]." [ZFA:0005059] subset: efo_slim subset: vertebrate_core synonym: "heart muscle trabecula" RELATED [] synonym: "heart muscle trabeculae" RELATED PLURAL [] synonym: "myocardial trabeculae carneae" RELATED PLURAL [] synonym: "myocardial trabecular layer" EXACT [] synonym: "trabecula of heart muscle" RELATED [] synonym: "trabeculae" RELATED [TAO:0005059] synonym: "trabecular layer" EXACT [ZFA:0005059] xref: EFO:0003706 xref: MA:0002866 xref: TAO:0005059 xref: ZFA:0005059 is_a: UBERON:0004123 ! myocardial layer intersection_of: UBERON:0004123 ! myocardial layer intersection_of: adjacent_to UBERON:0002165 ! endocardium intersection_of: composed_primarily_of GO:0036194 ! muscle cell projection relationship: adjacent_to UBERON:0002165 ! endocardium relationship: composed_primarily_of GO:0036194 ! muscle cell projection property_value: UBPROP:0000001 "The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the the endocardium. Unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae of the zebrafish have more strut-like character, and are more uniform without apparent regional differences Hu et al. 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005059", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0004126 name: trabecular layer of ventricle namespace: uberon def: "A myocardium trabecular layer that is part of a cardiac ventricle." [OBOL:automatic] subset: vertebrate_core synonym: "myocardium of region of ventricle" EXACT [FMA:83511] synonym: "trabecular cardiac ventricle muscle" EXACT [GO:0003222] synonym: "ventricular trabecular myocardium" EXACT [GO:0003222] xref: FMA:83511 xref: TAO:0005060 xref: ZFA:0005060 is_a: UBERON:0004124 ! myocardium trabecular layer intersection_of: UBERON:0004124 ! myocardium trabecular layer intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0001083 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! myocardium of ventricle property_value: editor_note "TODO - check FMA" xsd:string [Term] id: UBERON:0004128 name: optic vesicle namespace: uberon def: "The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]." [GO:0003404, Wikipedia:Optic_vesicles] comment: Genes: Six3, Pax6, Rx1 are expressed together in the tip of the neural plate [ISBN:9780878932504 "Developmental Biology"]. Development notes: During subsequent develop- ment, the optic vesicle invaginates and becomes a two-layered structure with an inner neural retina and outer retinal pigment epithelium. As soon as the developing optic vesicle makes contact with the overlying ectoderm, it induces the ectoderm to thicken and form the lens placode [PMID:16496288] subset: pheno_slim subset: vertebrate_core synonym: "evagination" RELATED [] synonym: "eye vesicle" RELATED [XAO:0000228] synonym: "ocular vesicle" RELATED [VHOG:0000165] synonym: "optic vesicles" RELATED PLURAL [ZFA:0000050] xref: AAO:0011039 xref: EHDAA2:0001320 xref: EMAPA:16540 xref: FMA:293357 xref: NCIT:C34236 xref: SCTID:362864008 xref: TAO:0000050 xref: UMLS:C0231106 {source="ncithesaurus:Optic_Vesicle"} xref: VHOG:0000165 xref: Wikipedia:Optic_vesicles xref: XAO:0000228 xref: ZFA:0000050 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000479 ! tissue is_a: UBERON:0004121 ! ectoderm-derived structure relationship: developmentally_induced_by UBERON:0004880 ! chordamesoderm relationship: develops_from UBERON:0002346 {source="GO-def"} ! neurectoderm relationship: develops_from UBERON:0003071 {source="ZFA"} ! eye primordium relationship: part_of UBERON:0010312 {source="ZFA"} ! immature eye property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png" xsd:anyURI property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000165", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004133 name: salivatory nucleus namespace: uberon def: "." [GO:0021751] synonym: "salivary nucleus" EXACT [GO:0021751] is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus relationship: part_of UBERON:0000988 ! pons [Term] id: UBERON:0004139 name: cardiogenic plate namespace: uberon def: "The first recognizable structure derived from the heart field." [GO:0003142] subset: pheno_slim synonym: "cardiac crescent" RELATED [EMAPA:16106] synonym: "cardiogenic crescent" RELATED [GO:0003142] synonym: "heart rudiment" RELATED [] synonym: "myocardial plate" EXACT [EHDAA2:0000215] xref: EHDAA2:0000215 xref: EMAPA:16106 xref: VHOG:0000975 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0003084 ! heart primordium property_value: editor_note "TODO - check plate vs rudiment vs primordium vs endocardial tube. See XAO" xsd:string property_value: UBPROP:0000003 "(In vertebrates) The embryonic mesoderm is the source of both the cardiogenic plate, giving rise to the future myocardium as well as the endocardium that will line the system on the inner side.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000975", ontology="VHOG", source="PMID:15611355 Gittenberger-de Groot AC, Bartelings MM, Deruiter MC, Poelmann RE, Basics of cardiac development for the understanding of congenital heart malformations. Pediatric Research (2005)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004140 name: primary heart field namespace: uberon def: "A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle." [GO:0003138, GOC:mtg_heart, GOC:rl] synonym: "FHF" RELATED ABBREVIATION [XAO:0004185] synonym: "first heart field" EXACT [XAO:0004185] synonym: "heart field" RELATED [XAO:0004185] synonym: "PHF" RELATED ABBREVIATION [XAO:0004185] synonym: "primary heart field" EXACT [PMID:17276708, XAO:0004185] xref: XAO:0004185 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007688 ! anlage relationship: part_of UBERON:0003081 {source="GO:0003128"} ! lateral plate mesoderm relationship: part_of UBERON:0036146 {source="https://orcid.org/0000-0003-3308-6245"} ! cardiopharyngeal field property_value: UBPROP:0000012 "this term denotes the primary heart field; GO:0003128 denotes the superclass of primary and secondary: specific region of the lateral mesoderm into the area which will form the primary beating heart tube[GO:0003138]" xsd:string {external_ontology="GO"} [Term] id: UBERON:0004141 name: heart tube namespace: uberon def: "An epithelial tube that will give rise to the mature heart." [GO:0003143, GOC:mtg_heart] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "embryonic heart tube" EXACT [GO:0003143] synonym: "endocardial heart tube" EXACT [MP:0012700] synonym: "endocardial tube" EXACT [XAO:0000337] xref: AAO:0010411 xref: EFO:0003526 xref: EMAPA:32685 xref: NCIT:C34161 xref: TAO:0000360 xref: XAO:0000337 xref: ZFA:0000360 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0012275 ! meso-epithelium relationship: develops_from UBERON:0005498 ! primitive heart tube relationship: immediate_transformation_of UBERON:0005498 {source="ZFA-modified"} ! primitive heart tube property_value: UBPROP:0000001 "the paired, longitudinal, endothelial-lined channels formed from the cardiogenic mesoderm in embryonic development; angiogenic cell clusters (aka angioblastic cords) located in a horse-shoe shape configuration in the cardiogenic plate coalesce to form the right and left endocardial heart tubes which then fuse in cephalo-caudal direction to form a single primitive heart tube." xsd:string {source="MP:0012700"} [Term] id: UBERON:0004142 name: outflow tract septum namespace: uberon def: "The outflow tract septum is a partition in the outflow tract." [GO:0003148] xref: XAO:0004141 is_a: UBERON:0002099 ! cardiac septum intersection_of: UBERON:0002099 ! cardiac septum intersection_of: part_of UBERON:0004145 ! outflow tract relationship: part_of UBERON:0004145 ! outflow tract [Term] id: UBERON:0004145 name: outflow tract namespace: uberon def: "The outflow tract is the portion of the heart through which blood flows into the arteries." [GO:0003151] subset: pheno_slim synonym: "arterial (outflow) pole" RELATED [PMID:20735616] synonym: "cardiac outflow tract" EXACT [PMID:20735616] synonym: "heart outflow tract" EXACT [] xref: EHDAA2:0001351 xref: EHDAA:464 xref: EHDAA:798 xref: EMAPA:16346 xref: MA:0000100 xref: VHOG:0000670 xref: XAO:0004139 is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure relationship: channel_for UBERON:0000178 ! blood relationship: channels_from UBERON:0000948 ! heart relationship: channels_into UBERON:0001637 ! artery relationship: part_of UBERON:0000948 ! heart property_value: UBPROP:0000008 "Depending on the species, attached at the cardiac outflow are described the conus arteriosus, the truncus arteriosus and, or the bulbus arteriosus. At the distal limit of these outflow structures, but lying outside the pericardial cavity, is the ventral aorta[PMID:20735616]" xsd:string [Term] id: UBERON:0004146 name: His-Purkinje system namespace: uberon def: "The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." [GO:0003164, https://github.com/geneontology/go-ontology/issues/12451] synonym: "His-Purkinji network" EXACT [] synonym: "HPS" EXACT ABBREVIATION [] synonym: "VCS" EXACT [] synonym: "ventricular conduction system" EXACT [] is_a: UBERON:0010131 {source="cjm"} ! conducting tissue of heart is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: only_in_taxon NCBITaxon:32523 {source="PMID:12626327", source="PMID:21234997", source="github:michaelerice"} ! Tetrapoda relationship: part_of UBERON:0002350 {source="GO"} ! conducting system of heart property_value: UBPROP:0000001 "the intraventricular conduction system from the bundle of His to the distal Purkinje fibers, which carries the impulse to the ventricles." xsd:string {source="http://medical-dictionary.thefreedictionary.com/His-Purkinje+system"} [Term] id: UBERON:0004148 name: cardiac vein namespace: uberon def: "Vein of heart that drains the myocardium." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "cardiac vein" EXACT [FMA:12846] synonym: "coronary vein" EXACT [ZFA:0005814] synonym: "coronary vein" RELATED [Wikipedia:Coronary_circulation] synonym: "heart vein" EXACT [OBOL:automatic] synonym: "vein of heart" EXACT [OBOL:automatic] xref: EHDAA2:0004507 xref: EMAPA:37137 {source="MA:th"} xref: FMA:12846 xref: galen:CoronaryVein xref: NCIT:C12878 xref: NCIT:C12882 xref: SCTID:277726009 xref: UMLS:C0226654 {source="ncithesaurus:Cardiac_Vein"} xref: UMLS:C0226737 {source="ncithesaurus:Coronary_Vein"} xref: Wikipedia:Coronary_circulation xref: ZFA:0005814 is_a: UBERON:0003498 ! heart blood vessel is_a: UBERON:0005194 ! thoracic vein is_a: UBERON:0013140 {source="FMA"} ! systemic vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0000948 ! heart relationship: drains UBERON:0002349 ! myocardium relationship: part_of RO:0002577 ! system [Term] id: UBERON:0004151 name: cardiac chamber namespace: uberon def: "A cardiac chamber surrounds an enclosed cavity within the heart." [GO:0003205] comment: generic enough to cover FBbt:00003156 heart chamber but this is a cavity. GO defines it as the cavity. TODO - move subclasses. Note this also includes sinus venosus synonym: "chamber of heart" EXACT [] synonym: "heart chamber" EXACT [] xref: FMA:7095 xref: SCTID:276456008 is_a: UBERON:0000064 ! organ part is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of UBERON:0000948 ! heart [Term] id: UBERON:0004160 name: proepicardium namespace: uberon def: "An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium." [GO:0003342, http://en.wiktionary.org/wiki/proepicardium] synonym: "proepicardial cluster" EXACT [ZFA:0005808] synonym: "proepicardial organ" EXACT [ZFIN:ZDB-PUB-080218-16] xref: EMAPA:36025 xref: ZFA:0005808 is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0004161 {notes="todo check other taxa"} ! septum transversum relationship: part_of UBERON:0004535 {source="ZFA"} ! cardiovascular system property_value: UBPROP:0000007 "propepicardial" xsd:string property_value: UBPROP:0000008 "Proepicardial clusters in Zebrafish form on the pericardial wall, adjacent to the atrioventricular (AV) junction and near the venous pole[ZFA]" xsd:string [Term] id: UBERON:0004161 name: septum transversum namespace: uberon def: "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]." [VHOG:0000019, Wikipedia:Septum_transversum] subset: pheno_slim synonym: "transverse septum" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001829 xref: EHDAA:736 xref: EMAPA:16318 xref: FMA:295593 xref: NCIT:C34296 xref: SCTID:308819008 xref: UMLS:C0231004 {source="ncithesaurus:Septum_Transversum"} xref: VHOG:0000019 xref: Wikipedia:Septum_transversum is_a: UBERON:0003104 ! mesenchyme relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: part_of UBERON:0002100 ! trunk property_value: UBPROP:0000001 "A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000019", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/transverse+septum"} property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart (of other tetrapods) is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes) Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000019", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "The cranial part of the septum transversum gives rise to the central tendon of the diaphragm and is the origin of the myoblasts that invade the pleuroperitoneal folds resulting in the formation of the muscular diaphragm. The caudal part of the septum transversum is invaded by the hepatic diverticulum which divides within it to form the liver and thus gives rise to the ventral mesentery of the foregut." xsd:string property_value: UBPROP:0000012 "in EHDAA2 this is divided into mesenchymal portion and hepatic diverticulum" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0004175 name: internal genitalia namespace: uberon def: "The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." [GO:0035260] comment: TODO: make a subdivision of reproductive system. Relabel. See https://github.com/obophenotype/uberon/issues/547 subset: organ_slim subset: pheno_slim synonym: "internal genitalia" EXACT [] synonym: "internal genitals" EXACT [] synonym: "internal reproductive organ" RELATED [] synonym: "internal sex organ" RELATED [] xref: FMA:45652 is_a: UBERON:0003133 ! reproductive organ [Term] id: UBERON:0004176 name: external genitalia namespace: uberon def: "The external genitalia are the outer sex organs, such as the penis or vulva in mammals." [GO:0035261] comment: TODO: make a subdivision of reproductive system. Relabel. See https://github.com/obophenotype/uberon/issues/547 subset: organ_slim subset: pheno_slim synonym: "external genitalia" EXACT [] synonym: "external reproductive organ" RELATED [] synonym: "external sex organ" RELATED [] xref: FMA:45643 xref: SCTID:362207005 is_a: UBERON:0003133 ! reproductive organ [Term] id: UBERON:0004177 name: hemopoietic organ namespace: uberon def: "Organ that is part of the hematopoietic system." [GOC:Obol] subset: organ_slim subset: pheno_slim synonym: "haematological system organ" EXACT [OBOL:automatic] synonym: "haemopoietic system organ" EXACT [OBOL:automatic] synonym: "hematopoeitic or lymphoid organ" NARROW [] synonym: "hematopoeitic organ" EXACT [] synonym: "hematopoietic system organ" EXACT [OBOL:automatic] synonym: "lymph organ" NARROW [MA:0000747] synonym: "lymphoid organ" NARROW [BTO:0004605, FMA:7143] synonym: "organ of haematological system" EXACT [OBOL:automatic] synonym: "organ of haemopoietic system" EXACT [OBOL:automatic] synonym: "organ of hematopoietic system" EXACT [OBOL:automatic] synonym: "organ of organa haemopoietica" EXACT [OBOL:automatic] synonym: "organa haemopoietica organ" EXACT [OBOL:automatic] xref: BTO:0004605 xref: EMAPA:37665 {source="MA:th"} xref: FMA:7143 xref: MA:0000747 xref: SCTID:361338006 is_a: UBERON:0000062 ! organ is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002390 ! hematopoietic system relationship: part_of UBERON:0002390 ! hematopoietic system property_value: editor_note "consider splitting out lymph organ, compare with lymph node" xsd:string property_value: UBPROP:0000001 "the organs in which the formed elements of the blood and lymph are produced[http://encyclopedia2.thefreedictionary.com/Hematopoietic+Organs]." xsd:string {source="http://encyclopedia2.thefreedictionary.com/Hematopoietic+Organs"} property_value: UBPROP:0000012 "the FMA class 'lymphoid organ' is a general anatomical term" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004178 name: aorta smooth muscle tissue namespace: uberon def: "The nonstriated, involuntary muscle tissue located in the wall of the aorta." [MGI:csmith, MP:0009865] subset: efo_slim subset: pheno_slim synonym: "aorta non-striated muscle" EXACT [OBOL:automatic] synonym: "aorta smooth muscle" EXACT [OBOL:automatic] synonym: "aortic smooth muscle" EXACT [BTO:0001685] xref: BTO:0001685 xref: CALOHA:TS-0048 xref: EFO:0002775 xref: EMAPA:35135 xref: MA:0000702 xref: NCIT:C49191 xref: UMLS:C1706825 {source="ncithesaurus:Aorta_Smooth_Muscle_Tissue"} is_a: UBERON:0004237 ! blood vessel smooth muscle is_a: UBERON:0004695 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000947 ! aorta relationship: part_of UBERON:0000947 ! aorta [Term] id: UBERON:0004183 name: placental labyrinth blood vessel namespace: uberon def: "The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." [GO:0060716] synonym: "blood vessel of labyrinthine layer" EXACT [OBOL:automatic] synonym: "blood vessel of labyrinthine layer of placenta" EXACT [OBOL:automatic] synonym: "blood vessel of placenta labyrinth" EXACT [OBOL:automatic] synonym: "labyrinthine layer blood vessel" EXACT [GO:0060716] synonym: "labyrinthine layer of placenta blood vessel" EXACT [OBOL:automatic] synonym: "placenta labyrinth blood vessel" EXACT [OBOL:automatic] is_a: UBERON:0022358 ! placenta blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003946 ! placenta labyrinth relationship: part_of UBERON:0003970 ! placental labyrinth vasculature [Term] id: UBERON:0004185 name: endodermal part of digestive tract namespace: uberon def: "A portions of the gut that is derived from endoderm." [GO:0061031] synonym: "endodermal gut" EXACT [] synonym: "gut endoderm" EXACT [EMAPA:32930] xref: EMAPA:32930 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004921 ! subdivision of digestive tract intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0004203 name: cortical collecting duct namespace: uberon alt_id: UBERON:0005267 def: "The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." [GO:0072059] subset: human_reference_atlas synonym: "kidney cortex collecting duct" EXACT [MA:0002600] synonym: "renal cortex collecting duct" RELATED [MA:0002600] xref: BTO:0002643 xref: EMAPA:28130 xref: MA:0002600 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: part_of UBERON:0001225 ! cortex of kidney intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0001225 ! cortex of kidney relationship: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004208 name: nephrogenic mesenchyme namespace: uberon def: "Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." [GO:0072076] comment: The detailed events associated with the differentiation of the nephrogenic mesenchyme are somewhat complex. It has been suggested that each terminal branch of the ureteric bud stimulates the associated cap mesenchyme tissue to form a renal vesicle (the most primitive stage of nephron development: a stage I nephron). This then elongates, becomes a comma-shaped and then an S-shaped body (stage II nephron), and makes contact with and fuses with the distal component of the ureteric bud. The latter then forms the collecting duct. One fold of the S-shaped body gives rise to Bowman's capsule (also termed the glomerular capsule). Soon afterwards, endothelial cells invade to make a capillary knot-like outgrowth, the glomerular tuft, which goes on to form the glomerulus. The inner epithelial layer of the Bowman's capsule (also called the visceral epithelium, or podocyte layer because it consists of podocytes) is closely apposed to the endothelial glomerulus. Together, the Bowman's capsule and the glomerulus comprise the definitive renal corpuscle. The rest of the nephron elongates to form components of the proximal tubule, the loop of Henle and the distal tubule. The distal pole of the developing nephron connects to the ureteric bud that induced it at an early stage of nephron/ collecting duct development, before differentiation of the proximal tubule, the loop of Henle and the distal tubule are complete. This connection allows the excretory products produced by the kidney to be removed and subsequently transferred, via the ureter, into the bladder where they are stored until it is appropriate to empty the bladder. [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "mesenchyme of nephron" EXACT [OBOL:automatic] synonym: "nephron mesenchyme" EXACT [OBOL:automatic] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: has_potential_to_develop_into UBERON:0001285 ! nephron relationship: has_potential_to_develop_into UBERON:0001285 ! nephron [Term] id: UBERON:0004209 name: renal vesicle namespace: uberon def: "The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." [GO:0072077] synonym: "stage I nephron" EXACT [http://www.gudmap.org/Organ_Summaries/Metanephros/Renal_vesicle.html, ZFA:0005586] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle relationship: developmentally_induced_by UBERON:0000084 ! ureteric bud relationship: develops_from UBERON:0004208 ! nephrogenic mesenchyme relationship: has_potential_to_develop_into UBERON:0004211 ! nephron epithelium relationship: part_of UBERON:0010536 ! nephron progenitor property_value: editor_note "note that this class includes both metanephric and mesonephric vesicles - ZFA and EHDAA2 associations are placed with these classes. TODO - make a more specific develops_from relationship - see UBERON:0005107 ! metanephric cap" xsd:string [Term] id: UBERON:0004211 name: nephron epithelium namespace: uberon def: "The nephron epithelium is a tissue that covers the surface of a nephron." [GO:0072088] synonym: "epithelial tissue of nephron" EXACT [OBOL:automatic] synonym: "epithelium of nephron" EXACT [OBOL:automatic] synonym: "nephron epithelial tissue" EXACT [OBOL:automatic] is_a: UBERON:0004819 ! kidney epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001285 ! nephron relationship: part_of UBERON:0001285 ! nephron [Term] id: UBERON:0004214 name: upper leg nerve namespace: uberon def: "A nerve that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb stylopod nerve" EXACT [OBOL:automatic] synonym: "hindlimb stylopod nerve" EXACT [OBOL:automatic] synonym: "lower extremity stylopod nerve" EXACT [OBOL:automatic] synonym: "thigh RELATED" EXACT [OBOL:automatic] xref: EMAPA:37344 {source="MA:th"} xref: MA:0000685 is_a: UBERON:0003431 ! leg nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004215 name: back nerve namespace: uberon def: "A nerve that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of back" EXACT [OBOL:automatic] xref: EMAPA:37268 {source="MA:th"} xref: MA:0000497 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004216 name: lower arm nerve namespace: uberon def: "A nerve that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37338 {source="MA:th"} xref: MA:0000601 is_a: UBERON:0003433 ! arm nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0002386 ! forelimb zeugopod [Term] id: UBERON:0004217 name: upper arm nerve namespace: uberon def: "A nerve that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37337 {source="MA:th"} xref: MA:0000607 is_a: UBERON:0003433 ! arm nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: part_of UBERON:0003822 ! forelimb stylopod [Term] id: UBERON:0004218 name: lower leg nerve namespace: uberon def: "A nerve that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37345 {source="MA:th"} xref: MA:0000679 is_a: UBERON:0003431 ! leg nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0003823 ! hindlimb zeugopod [Term] id: UBERON:0004219 name: urethra smooth muscle layer namespace: uberon def: "A portion of smooth muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "muscle layer of urethra" EXACT [FMA:76909] synonym: "muscular coat of urethra" EXACT [FMA:76909] synonym: "muscular layer of urethra" EXACT [FMA:76909] synonym: "smooth muscle of urethra" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urethra" EXACT [OBOL:automatic] synonym: "tunica muscularis urethrae" EXACT LATIN [FMA:TA] synonym: "urethra smooth muscle tissue" EXACT [OBOL:automatic] synonym: "urethral smooth muscle" RELATED [MA:0001691] xref: EMAPA:36630 xref: FMA:76909 xref: MA:0001691 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0004220 name: large intestine smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of large intestine" EXACT [OBOL:automatic] synonym: "large intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "large intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "large intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of large intestine" EXACT [OBOL:automatic] synonym: "smooth muscle of large intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of large intestine" EXACT [OBOL:automatic] xref: EMAPA:35469 xref: MA:0001547 is_a: UBERON:0004221 ! intestine smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000059 ! large intestine relationship: overlaps UBERON:0011198 {notes="consider merging"} ! muscle layer of large intestine relationship: part_of UBERON:0001169 {source="MA"} ! wall of large intestine property_value: UBPROP:0000012 "MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa" xsd:string {external_ontology="MA"} [Term] id: UBERON:0004221 name: intestine smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "bowel involuntary muscle" EXACT [OBOL:automatic] synonym: "bowel non-striated muscle" EXACT [OBOL:automatic] synonym: "bowel smooth muscle" EXACT [OBOL:automatic] synonym: "bowel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "intestinal muscularis" RELATED [EMAPA:35441] synonym: "intestinal smooth muscle" RELATED [BTO:0000643] synonym: "intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bowel" EXACT [OBOL:automatic] synonym: "involuntary muscle of intestine" EXACT [OBOL:automatic] synonym: "non-striated muscle of bowel" EXACT [OBOL:automatic] synonym: "non-striated muscle of intestine" EXACT [OBOL:automatic] synonym: "smooth muscle of bowel" EXACT [OBOL:automatic] synonym: "smooth muscle of intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bowel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of intestine" EXACT [OBOL:automatic] xref: BTO:0000643 xref: EMAPA:35441 xref: EMAPA:35443 xref: MA:0001539 xref: NCIT:C49243 xref: UMLS:C1708547 {source="ncithesaurus:Intestinal_Smooth_Muscle_Tissue"} is_a: UBERON:0004226 ! gastrointestinal system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000160 ! intestine relationship: contributes_to_morphology_of UBERON:0000160 ! intestine relationship: overlaps UBERON:0012367 {notes="consider merging"} ! muscle layer of intestine relationship: part_of UBERON:0001262 ! wall of intestine property_value: UBPROP:0000012 "MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa" xsd:string {external_ontology="MA"} [Term] id: UBERON:0004222 name: stomach smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]." [OBOL:automatic] synonym: "gastric muscle" RELATED [BTO:0001818] synonym: "gastric smooth muscle" RELATED [MA:0001627] synonym: "involuntary muscle of stomach" EXACT [OBOL:automatic] synonym: "involuntary muscle of ventriculus" EXACT [OBOL:automatic] synonym: "non-striated muscle of stomach" EXACT [OBOL:automatic] synonym: "non-striated muscle of ventriculus" EXACT [OBOL:automatic] synonym: "smooth muscle of stomach" EXACT [OBOL:automatic] synonym: "smooth muscle of ventriculus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of stomach" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of ventriculus" EXACT [OBOL:automatic] synonym: "stomach involuntary muscle" EXACT [OBOL:automatic] synonym: "stomach muscle" RELATED [BTO:0001818] synonym: "stomach non-striated muscle" EXACT [OBOL:automatic] synonym: "stomach smooth muscle tissue" EXACT [OBOL:automatic] synonym: "ventriculus involuntary muscle" EXACT [OBOL:automatic] synonym: "ventriculus non-striated muscle" EXACT [OBOL:automatic] synonym: "ventriculus smooth muscle" EXACT [OBOL:automatic] synonym: "ventriculus smooth muscle tissue" EXACT [OBOL:automatic] xref: BTO:0001818 xref: EMAPA:35823 xref: MA:0001627 is_a: UBERON:0004226 ! gastrointestinal system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0001167 ! wall of stomach [Term] id: UBERON:0004224 name: muscular coat of vas deferens namespace: uberon def: "A muscular coat that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] synonym: "muscle layer of deferent duct" EXACT [FMA:19239] synonym: "muscle layer of ductus deferens" EXACT [FMA:19239] synonym: "muscle layer of vas deferens" EXACT [FMA:19239] synonym: "muscular coat of ductus deferens" EXACT [FMA:19239] synonym: "muscular layer of ductus deferens" EXACT [FMA:19239] synonym: "muscularis of vas deferens" EXACT [FMA:19239] synonym: "tunica muscularis (ductus deferens)" EXACT [FMA:19239] synonym: "tunica muscularis ductus deferentis" EXACT LATIN [FMA:19239, FMA:TA] xref: EMAPA:29270 xref: FMA:19239 xref: MA:0001750 xref: SCTID:299705008 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0006660 ! muscular coat is_a: UBERON:0034933 ! layer of smooth muscle tissue intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001000 ! vas deferens relationship: part_of UBERON:0001000 ! vas deferens property_value: editor_note "TODO - check MA and FMA classes mean the same thing" xsd:string [Term] id: UBERON:0004225 name: respiratory system smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "airway smooth muscle" RELATED [BTO:0001660] synonym: "airway smooth muscle cell" RELATED [BTO:0001660] synonym: "respiratory smooth muscle" EXACT [BTO:0001660] synonym: "smooth muscle of respiratory system" EXACT [OBOL:automatic] xref: BTO:0001660 xref: EMAPA:35734 xref: MA:0001830 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0004226 name: gastrointestinal system smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "smooth muscle tissue of gastrointestinal system" EXACT [OBOL:automatic] xref: EMAPA:35117 xref: MA:0001523 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system [Term] id: UBERON:0004227 name: kidney pelvis smooth muscle namespace: uberon def: "The smooth muscle tissue surrounding the urothelium of the kidney pelvis." [MGI:csmith, MP:0011335] subset: pheno_slim synonym: "kidney pelvis smooth muscle" EXACT [EMAPA:28120] synonym: "pelvic smooth muscle" RELATED [EMAPA:28120] synonym: "renal pelvis smooth muscle" EXACT [EMAPA:28120] synonym: "smooth muscle tissue of renal pelvis" EXACT [FMA:262022] xref: EMAPA:28120 xref: FMA:262022 xref: MA:0002631 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001224 ! renal pelvis relationship: contributes_to_morphology_of UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: UBERON:0004228 name: urinary bladder smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle" EXACT [OBOL:automatic] synonym: "bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle layer of bladder" RELATED [] synonym: "smooth muscle of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder" EXACT [OBOL:automatic] synonym: "urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder muscle" EXACT [MA:0001697] synonym: "urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] xref: BTO:0001849 xref: CALOHA:TS-1087 xref: EMAPA:37791 {source="MA:th"} xref: MA:0001697 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 ! urinary bladder [Term] id: UBERON:0004230 name: urinary bladder neck smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck involuntary muscle" EXACT [OBOL:automatic] synonym: "bladder neck non-striated muscle" EXACT [OBOL:automatic] synonym: "bladder neck smooth muscle" EXACT [OBOL:automatic] synonym: "bladder neck smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bladder neck" EXACT [OBOL:automatic] synonym: "involuntary muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "involuntary muscle of vesical neck" EXACT [OBOL:automatic] synonym: "neck of bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "neck of bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "neck of bladder smooth muscle" EXACT [OBOL:automatic] synonym: "neck of bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "neck of urinary bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder smooth muscle" EXACT [OBOL:automatic] synonym: "neck of urinary bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of bladder neck" EXACT [OBOL:automatic] synonym: "non-striated muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "non-striated muscle of vesical neck" EXACT [OBOL:automatic] synonym: "smooth muscle of bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle of neck of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of urinary bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle of vesical neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of neck of bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of urinary bladder neck" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of vesical neck" EXACT [OBOL:automatic] synonym: "trigonal muscle" EXACT [FMA:67990] synonym: "trigonal muscle of urinary bladder" EXACT [FMA:67990] synonym: "urinary bladder neck involuntary muscle" EXACT [OBOL:automatic] synonym: "urinary bladder neck muscle" EXACT [MA:0001699] synonym: "urinary bladder neck non-striated muscle" EXACT [OBOL:automatic] synonym: "urinary bladder neck smooth muscle tissue" EXACT [OBOL:automatic] synonym: "vesical neck involuntary muscle" EXACT [OBOL:automatic] synonym: "vesical neck non-striated muscle" EXACT [OBOL:automatic] synonym: "vesical neck smooth muscle" EXACT [OBOL:automatic] synonym: "vesical neck smooth muscle tissue" EXACT [OBOL:automatic] xref: EMAPA:30123 xref: FMA:67990 xref: MA:0001699 is_a: UBERON:0004228 ! urinary bladder smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001258 ! neck of urinary bladder relationship: part_of UBERON:0001258 ! neck of urinary bladder [Term] id: UBERON:0004231 name: anal region smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]." [OBOL:automatic] synonym: "anal part of perineum involuntary muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum non-striated muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum smooth muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum smooth muscle tissue" EXACT [OBOL:automatic] synonym: "anal region involuntary muscle" EXACT [OBOL:automatic] synonym: "anal region non-striated muscle" EXACT [OBOL:automatic] synonym: "anal region smooth muscle tissue" EXACT [OBOL:automatic] synonym: "anal triangle involuntary muscle" EXACT [OBOL:automatic] synonym: "anal triangle non-striated muscle" EXACT [OBOL:automatic] synonym: "anal triangle smooth muscle" EXACT [OBOL:automatic] synonym: "anal triangle smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal region" EXACT [OBOL:automatic] synonym: "involuntary muscle of anal triangle" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal region" EXACT [OBOL:automatic] synonym: "non-striated muscle of anal triangle" EXACT [OBOL:automatic] synonym: "smooth muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "smooth muscle of anal region" EXACT [OBOL:automatic] synonym: "smooth muscle of anal triangle" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal part of perineum" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal region" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of anal triangle" EXACT [OBOL:automatic] xref: EMAPA:37394 {source="MA:th"} xref: MA:0001532 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001353 ! anal region relationship: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0004233 name: lower respiratory tract smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract involuntary muscle" EXACT [OBOL:automatic] synonym: "lower respiratory tract non-striated muscle" EXACT [OBOL:automatic] synonym: "lower respiratory tract smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "smooth muscle of lower respiratory tract" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of lower respiratory tract" EXACT [OBOL:automatic] xref: EMAPA:35520 xref: MA:0002410 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0004225 ! respiratory system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001558 ! lower respiratory tract relationship: part_of UBERON:0001558 ! lower respiratory tract [Term] id: UBERON:0004234 name: iris smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of iris" EXACT [OBOL:automatic] synonym: "iridial smooth muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "iris involuntary muscle" EXACT [OBOL:automatic] synonym: "iris non-striated muscle" EXACT [OBOL:automatic] synonym: "iris smooth muscle tissue" EXACT [OBOL:automatic] synonym: "non-striated muscle of iris" EXACT [OBOL:automatic] synonym: "smooth muscle of iris" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of iris" EXACT [OBOL:automatic] xref: BTO:0000655 xref: EMAPA:35448 xref: FMA:312338 xref: MA:0001270 is_a: UBERON:0003386 {source="MA"} ! smooth muscle of eye intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001769 ! iris relationship: part_of UBERON:0001606 ! muscle of iris property_value: editor_note "see notes for muscle of iris." xsd:string [Term] id: UBERON:0004236 name: arteriole smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:36287 xref: FMA:312251 xref: MA:0000706 is_a: UBERON:0004237 ! blood vessel smooth muscle is_a: UBERON:0004695 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001980 ! arteriole relationship: part_of UBERON:0001980 ! arteriole [Term] id: UBERON:0004237 name: blood vessel smooth muscle namespace: uberon alt_id: UBERON:0010508 def: "Smooth muscle found within, and composing the majority of the wall of blood vessels." [Wikipedia:Vascular_smooth_muscle] subset: pheno_slim synonym: "blood vessel involuntary muscle" EXACT [OBOL:automatic] synonym: "blood vessel non-striated muscle" EXACT [OBOL:automatic] synonym: "blood vessel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of blood vessel" EXACT [OBOL:automatic] synonym: "non-striated muscle of blood vessel" EXACT [OBOL:automatic] synonym: "smooth muscle of blood vessel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of blood vessel" EXACT [OBOL:automatic] synonym: "vascular smooth muscle" EXACT [ZFA:0005321] synonym: "vascular smooth muscle tissue" EXACT [] xref: BTO:0001431 xref: CALOHA:TS-1107 xref: EMAPA:35177 xref: MA:0000710 xref: MESH:D009131 xref: NCIT:C33853 xref: TAO:0005321 xref: UMLS:C1519956 {source="ncithesaurus:Vascular_Smooth_Muscle_Tissue"} xref: Wikipedia:Vascular_smooth_muscle xref: ZFA:0005321 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel property_value: UBPROP:0000009 "Vascular smooth muscle contracts or relaxes to both change the volume of blood vessels and the local blood pressure, a mechanism that is responsible for the redistribution of the blood within the body to areas where it is needed (i.e. areas with temporarily enhanced oxygen consumption). Thus the main function of vascular smooth muscle tonus is to regulate the caliber of the blood vessels in the body. Excessive vasoconstriction leads to hypertension, while excessive vasodilation as in shock leads to hypotension." xsd:string [Term] id: UBERON:0004238 name: spleen smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of spleen" EXACT [OBOL:automatic] synonym: "non-striated muscle of spleen" EXACT [OBOL:automatic] synonym: "smooth muscle of spleen" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of spleen" EXACT [OBOL:automatic] synonym: "spleen involuntary muscle" EXACT [OBOL:automatic] synonym: "spleen non-striated muscle" EXACT [OBOL:automatic] synonym: "spleen smooth muscle tissue" EXACT [OBOL:automatic] xref: EMAPA:35807 xref: MA:0000757 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0002106 ! spleen [Term] id: UBERON:0004239 name: small intestine smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "involuntary muscle of small bowel" EXACT [OBOL:automatic] synonym: "involuntary muscle of small intestine" EXACT [OBOL:automatic] synonym: "non-striated muscle of small bowel" EXACT [OBOL:automatic] synonym: "non-striated muscle of small intestine" EXACT [OBOL:automatic] synonym: "small bowel involuntary muscle" EXACT [OBOL:automatic] synonym: "small bowel non-striated muscle" EXACT [OBOL:automatic] synonym: "small bowel smooth muscle" EXACT [OBOL:automatic] synonym: "small bowel smooth muscle tissue" EXACT [OBOL:automatic] synonym: "small intestine involuntary muscle" EXACT [OBOL:automatic] synonym: "small intestine non-striated muscle" EXACT [OBOL:automatic] synonym: "small intestine smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of small bowel" EXACT [OBOL:automatic] synonym: "smooth muscle of small intestine" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of small bowel" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of small intestine" EXACT [OBOL:automatic] xref: EMAPA:35783 xref: MA:0001559 is_a: UBERON:0004221 ! intestine smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002108 ! small intestine relationship: overlaps UBERON:0011201 {notes="consider merging"} ! muscle layer of small intestine relationship: part_of UBERON:0001168 ! wall of small intestine property_value: UBPROP:0000012 "MA class may specifically mean muscle layer, but we treat as the sum of smooth muscle in both muscle layer and muscularis mucosa" xsd:string {external_ontology="MA"} [Term] id: UBERON:0004240 name: gallbladder smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "biliary smooth muscle" RELATED [MA:0001635] synonym: "gall bladder involuntary muscle" EXACT [OBOL:automatic] synonym: "gall bladder non-striated muscle" EXACT [OBOL:automatic] synonym: "gall bladder smooth muscle" EXACT [OBOL:automatic] synonym: "gall bladder smooth muscle tissue" EXACT [OBOL:automatic] synonym: "gallbladder involuntary muscle" EXACT [OBOL:automatic] synonym: "gallbladder non-striated muscle" EXACT [OBOL:automatic] synonym: "gallbladder smooth muscle tissue" EXACT [] synonym: "involuntary muscle of gall bladder" EXACT [OBOL:automatic] synonym: "involuntary muscle of gallbladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of gall bladder" EXACT [OBOL:automatic] synonym: "non-striated muscle of gallbladder" EXACT [OBOL:automatic] synonym: "smooth muscle of gall bladder" EXACT [OBOL:automatic] synonym: "smooth muscle of gallbladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gall bladder" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of gallbladder" EXACT [OBOL:automatic] xref: EMAPA:35373 xref: MA:0001635 xref: NCIT:C49483 xref: UMLS:C1708179 {source="ncithesaurus:Gallbladder_Smooth_Muscle_Tissue"} is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: UBERON:0004242 name: bronchus smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "bronchi involuntary muscle" EXACT [OBOL:automatic] synonym: "bronchi non-striated muscle" EXACT [OBOL:automatic] synonym: "bronchi smooth muscle" EXACT [OBOL:automatic] synonym: "bronchi smooth muscle tissue" EXACT [OBOL:automatic] synonym: "bronchial smooth muscle" RELATED [EMAPA:35195] synonym: "bronchial trunk involuntary muscle" EXACT [OBOL:automatic] synonym: "bronchial trunk non-striated muscle" EXACT [OBOL:automatic] synonym: "bronchial trunk smooth muscle" EXACT [OBOL:automatic] synonym: "bronchial trunk smooth muscle tissue" EXACT [OBOL:automatic] synonym: "bronchus involuntary muscle" EXACT [OBOL:automatic] synonym: "bronchus non-striated muscle" EXACT [OBOL:automatic] synonym: "bronchus smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of bronchi" EXACT [OBOL:automatic] synonym: "involuntary muscle of bronchial trunk" EXACT [OBOL:automatic] synonym: "involuntary muscle of bronchus" EXACT [OBOL:automatic] synonym: "non-striated muscle of bronchi" EXACT [OBOL:automatic] synonym: "non-striated muscle of bronchial trunk" EXACT [OBOL:automatic] synonym: "non-striated muscle of bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle of bronchi" EXACT [OBOL:automatic] synonym: "smooth muscle of bronchial trunk" EXACT [OBOL:automatic] synonym: "smooth muscle of bronchus" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bronchi" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bronchial trunk" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of bronchus" EXACT [OBOL:automatic] xref: BTO:0004401 xref: EMAPA:35195 xref: MA:0001840 xref: NCIT:C49213 xref: UMLS:C1707055 {source="ncithesaurus:Bronchus_Smooth_Muscle_Tissue"} is_a: UBERON:0004233 ! lower respiratory tract smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 ! bronchus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004245 name: oviduct smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a fallopian tube [Automatically generated definition]." [OBOL:automatic] synonym: "fallopian tube involuntary muscle" EXACT [OBOL:automatic] synonym: "fallopian tube non-striated muscle" EXACT [OBOL:automatic] synonym: "fallopian tube smooth muscle" EXACT [OBOL:automatic] synonym: "fallopian tube smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "non-striated muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "smooth muscle of fallopian tube" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of fallopian tube" EXACT [OBOL:automatic] xref: EMAPA:29046 xref: MA:0001721 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: part_of UBERON:0003889 ! fallopian tube [Term] id: UBERON:0004246 name: outflow tract smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "involuntary muscle of outflow tract" EXACT [OBOL:automatic] synonym: "non-striated muscle of outflow tract" EXACT [OBOL:automatic] synonym: "outflow tract involuntary muscle" EXACT [OBOL:automatic] synonym: "outflow tract non-striated muscle" EXACT [OBOL:automatic] synonym: "outflow tract smooth muscle tissue" EXACT [OBOL:automatic] synonym: "smooth muscle of outflow tract" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of outflow tract" EXACT [OBOL:automatic] xref: EMAPA:37708 {source="MA:th"} xref: MA:0000492 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0004145 ! outflow tract relationship: part_of UBERON:0004145 ! outflow tract [Term] id: UBERON:0004247 name: bone of dorsum namespace: uberon def: "A bone that is part of the dorsal region of an animal." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "back bone" RELATED [MA:0000494] synonym: "bone of back" RELATED [OBOL:automatic] synonym: "dorsal region bone" RELATED [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37248 {source="MA:th"} xref: MA:0000494 is_a: UBERON:0001474 ! bone element is_a: UBERON:0005174 ! dorsal region element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001137 ! dorsum property_value: IAO:0000232 "this class may be obsoleted. See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/93" xsd:string property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004248 name: pedal digit bone namespace: uberon def: "A bone that is part of a hindlimb digit. Typically phalanges but may include sesamoids." [https://orcid.org/0000-0002-6601-2165] synonym: "bone of digit of foot" EXACT [OBOL:automatic] synonym: "digit of foot bone" EXACT [OBOL:automatic] synonym: "digital bone of foot" EXACT [] synonym: "digital bone of pes" EXACT [] synonym: "digitus pedis bone" EXACT [OBOL:automatic] synonym: "digitus pedis bone organ" EXACT [OBOL:automatic] synonym: "foot digit bone" EXACT [MA:0000646] synonym: "foot digit bone" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "foot digit bone organ" EXACT [OBOL:automatic] synonym: "hind limb digit bone" EXACT [OBOL:accepted] synonym: "toe bone" EXACT [OBOL:automatic] synonym: "toe bone organ" EXACT [OBOL:automatic] xref: EMAPA:37309 {source="MA:th"} xref: MA:0000646 is_a: UBERON:0012359 ! pedal digitopodium bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:5101466 ! pedal digit digitopodial skeleton property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004249 name: manual digit bone namespace: uberon def: "A bone that is part of a forelimb digit. Typically phalanges but may include sesamoids." [https://orcid.org/0000-0002-6601-2165] synonym: "digital bone of hand" EXACT [] synonym: "digital bone of manus" EXACT [] synonym: "finger bone" EXACT [OBOL:automatic] synonym: "fore limb digit bone" EXACT [OBOL:accepted] synonym: "hand digit bone" EXACT [MA:0000622] synonym: "hand digit bone" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] xref: EMAPA:37305 {source="MA:th"} xref: MA:0000622 is_a: UBERON:0012358 ! manual digitopodium bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:5102389 ! manual digit digitopodial skeleton property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004250 name: upper arm bone namespace: uberon def: "A bone that is part of a forelimb stylopod [Automatically generated definition]." [https://sourceforge.net/tracker/index.php?func=detail&aid=3586533&group_id=76834&atid=1205376, OBOL:automatic] comment: May be merged into humerus. See: https://sourceforge.net/tracker/index.php?func=detail&aid=3586533&group_id=76834&atid=1205376 synonym: "humerus" NARROW [https://sourceforge.net/tracker/index.php?func=detail&aid=3586533&group_id=76834&atid=1205376] xref: EMAPA:35892 xref: MA:0000604 is_a: UBERON:0003460 ! arm bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: part_of UBERON:0003822 ! forelimb stylopod property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004251 name: hindlimb zeugopod bone namespace: uberon def: "A bone that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "bone of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "bone of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "bone of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "bone of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "bone of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "bone of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "bone of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "bone of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "bone of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "bone of lower leg" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "bone of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "bone of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "bone of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "bone of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "bone of zeugopod of leg" EXACT [OBOL:automatic] synonym: "bone of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "bone organ of hind limb middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of hind limb zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of hindlimb middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of hindlimb zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of inferior member middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of inferior member zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of intermediate segment of free lower limb" EXACT [OBOL:automatic] synonym: "bone organ of lower extremity middle limb segment" EXACT [OBOL:automatic] synonym: "bone organ of lower extremity zeugopod" EXACT [OBOL:automatic] synonym: "bone organ of lower leg" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of hind limb" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of hindlimb" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of inferior member" EXACT [OBOL:automatic] synonym: "bone organ of middle limb segment of lower extremity" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of hind limb" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of hindlimb" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of inferior member" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of leg" EXACT [OBOL:automatic] synonym: "bone organ of zeugopod of lower extremity" EXACT [OBOL:automatic] synonym: "hind limb middle limb segment bone" EXACT [OBOL:automatic] synonym: "hind limb middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "hind limb zeugopod bone" EXACT [OBOL:automatic] synonym: "hind limb zeugopod bone organ" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment bone" EXACT [OBOL:automatic] synonym: "hindlimb middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod bone" EXACT [OBOL:automatic] synonym: "hindlimb zeugopod bone organ" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment bone" EXACT [OBOL:automatic] synonym: "inferior member middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "inferior member zeugopod bone" EXACT [OBOL:automatic] synonym: "inferior member zeugopod bone organ" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb bone" EXACT [OBOL:automatic] synonym: "intermediate segment of free lower limb bone organ" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment bone" EXACT [OBOL:automatic] synonym: "lower extremity middle limb segment bone organ" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod bone" EXACT [OBOL:automatic] synonym: "lower extremity zeugopod bone organ" EXACT [OBOL:automatic] synonym: "lower leg bone" EXACT [MA:0000676] synonym: "middle limb segment of hind limb bone" EXACT [OBOL:automatic] synonym: "middle limb segment of hind limb bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb bone" EXACT [OBOL:automatic] synonym: "middle limb segment of hindlimb bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member bone" EXACT [OBOL:automatic] synonym: "middle limb segment of inferior member bone organ" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity bone" EXACT [OBOL:automatic] synonym: "middle limb segment of lower extremity bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb bone" EXACT [OBOL:automatic] synonym: "zeugopod of hind limb bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb bone" EXACT [OBOL:automatic] synonym: "zeugopod of hindlimb bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member bone" EXACT [OBOL:automatic] synonym: "zeugopod of inferior member bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of leg bone" EXACT [OBOL:automatic] synonym: "zeugopod of leg bone organ" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity bone" EXACT [OBOL:automatic] synonym: "zeugopod of lower extremity bone organ" EXACT [OBOL:automatic] xref: EMAPA:35519 xref: MA:0000676 is_a: UBERON:0005893 ! leg bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0003823 ! hindlimb zeugopod property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004252 name: hindlimb stylopod muscle namespace: uberon alt_id: UBERON:0000374 def: "Any muscle organ that is part of a hindlimb stylopod (upper leg)[Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "muscle of thigh" EXACT [FMA:22470] synonym: "thigh muscle" EXACT [FMA:22470] synonym: "upper leg muscle" EXACT [MA:0000684] xref: BTO:0001367 xref: EMAPA:19144 xref: FMA:22470 xref: MA:0000684 xref: SCTID:245013005 is_a: UBERON:0001383 ! muscle of leg intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0004463 {source="prolog"} ! musculature of hindlimb stylopod [Term] id: UBERON:0004253 name: skin muscle namespace: uberon alt_id: UBERON:0015797 def: "Any muscle organ that is part of a skin of body [Automatically generated definition]." [OBOL:automatic] synonym: "integumental system muscle" EXACT [MA:0003139] synonym: "muscle of integumental system" EXACT [EMAPA:18187] synonym: "muscle organ of skin" EXACT [OBOL:automatic] synonym: "skin muscle organ" EXACT [OBOL:automatic] xref: EMAPA:18187 xref: EMAPA:35776 xref: MA:0002710 xref: MA:0003139 is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0002416 ! integumental system relationship: located_in UBERON:0002097 ! skin of body relationship: part_of UBERON:0002416 ! integumental system property_value: editor_note "review as part of general integumentary system review - part of skin, or more generally, integumental system" xsd:string property_value: UBPROP:0000012 "in MA, the only skin muscle is arrector pili. The only integumental muscle is panniculus carnosus. In EMAPA, the arrector pili only" xsd:string {external_ontology="MA"} [Term] id: UBERON:0004254 name: forelimb zeugopod muscle namespace: uberon def: "Any muscle organ that is part of a forelimb zeugopod (lower arm)[Automatically generated definition]." [OBOL:automatic] synonym: "forearm muscle" EXACT [FMA:37371] synonym: "lower arm muscle" EXACT [MA:0000600] synonym: "muscle of forearm" EXACT [FMA:37371] synonym: "wing zeugopod muscle" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:32622 xref: FMA:37371 xref: MA:0000600 xref: SCTID:181631004 is_a: UBERON:0001499 ! muscle of arm intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0004487 {source="prolog"} ! musculature of forelimb zeugopod [Term] id: UBERON:0004255 name: forelimb stylopod muscle namespace: uberon def: "Any muscle organ that is part of a forelimb stylopod (upper arm)[Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "muscle of arm" RELATED INCONSISTENT [FMA:37370] synonym: "muscle of upper arm" EXACT [MA:0000606] synonym: "skeletal muscle of upper arm" RELATED [EMAPA:19107] synonym: "upper arm muscle" EXACT [MA:0000606] synonym: "wing stylopod muscle" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:19107 xref: FMA:37370 xref: MA:0000606 xref: SCTID:244979005 is_a: UBERON:0001499 ! muscle of arm intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: part_of UBERON:0014791 {source="prolog"} ! musculature of forelimb stylopod property_value: editor_note "the FMA class 'muscle of arm' belongs here, do not move" xsd:string property_value: UBPROP:0000013 "See notes on UBERON:0001460 for possible terminological confusion over term 'arm'" xsd:string [Term] id: UBERON:0004256 name: hindlimb zeugopod muscle namespace: uberon def: "Any muscle organ that is part of a hindlimb zeugopod (lower leg) [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "calf muscle" RELATED [OBOL:automatic] synonym: "lower leg muscle" EXACT [MA:0000678] synonym: "muscle of leg" RELATED INCONSISTENT [FMA:22471] xref: EMAPA:19318 xref: FMA:22471 xref: MA:0000678 xref: SCTID:265806001 is_a: UBERON:0001383 ! muscle of leg intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0006067 {source="prolog"} ! musculature of hindlimb zeugopod property_value: editor_note "the FMA class 'muscle of leg' belongs here, do not move[cjm]" xsd:string property_value: UBPROP:0000013 "See notes on UBERON:0000978 for possible terminological confusion over term 'leg'" xsd:string [Term] id: UBERON:0004257 name: upper leg blood vessel namespace: uberon def: "A blood vessel that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of stylopod of hind limb" EXACT [OBOL:automatic] synonym: "blood vessel of stylopod of hindlimb" EXACT [OBOL:automatic] synonym: "blood vessel of thigh" EXACT [OBOL:automatic] synonym: "blood vessel of upper leg" EXACT [OBOL:automatic] synonym: "hind limb stylopod blood vessel" EXACT [OBOL:automatic] synonym: "hindlimb stylopod blood vessel" EXACT [OBOL:automatic] synonym: "thigh blood vessel" EXACT [OBOL:automatic] xref: EMAPA:37299 {source="MA:th"} xref: MA:0000681 is_a: UBERON:0003503 ! leg blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004258 name: back blood vessel namespace: uberon def: "A blood vessel that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "blood vessel of back" EXACT [OBOL:automatic] xref: EMAPA:37243 {source="MA:th"} xref: MA:0000493 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004259 name: lower arm blood vessel namespace: uberon def: "A blood vessel that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "forelimb zeugopod blood vessel" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37295 {source="MA:th"} xref: MA:0000597 is_a: UBERON:0003507 ! arm blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0002386 ! forelimb zeugopod [Term] id: UBERON:0004260 name: upper arm blood vessel namespace: uberon def: "A blood vessel that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "forelimb stylopod blood vessel" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37294 {source="MA:th"} xref: MA:0000603 is_a: UBERON:0003507 ! arm blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: part_of UBERON:0003822 ! forelimb stylopod [Term] id: UBERON:0004261 name: lower leg blood vessel namespace: uberon def: "A blood vessel that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "hindlimb zeugopod blood vessel" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37300 {source="MA:th"} xref: MA:0000675 is_a: UBERON:0003503 ! leg blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0003823 ! hindlimb zeugopod [Term] id: UBERON:0004262 name: upper leg skin namespace: uberon def: "A zone of skin that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb stylopod skin" EXACT [OBOL:automatic] synonym: "hindlimb stylopod skin" EXACT [OBOL:automatic] synonym: "skin of thigh" RELATED [OBOL:automatic] synonym: "skin of upper leg" EXACT [OBOL:automatic] synonym: "thigh skin" RELATED [OBOL:automatic] xref: EMAPA:18159 xref: FMA:37790 xref: MA:0000686 xref: SCTID:181547006 is_a: UBERON:0001511 ! skin of leg intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004263 name: upper arm skin namespace: uberon def: "A zone of skin that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] synonym: "arm stylopod skin" EXACT [OBOL:automatic] synonym: "skin of arm stylopod" EXACT [OBOL:automatic] synonym: "skin of upper arm" EXACT [OBOL:automatic] xref: EMAPA:18062 xref: FMA:37721 xref: MA:0000608 xref: SCTID:181531009 is_a: UBERON:0002427 ! arm skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: part_of UBERON:0003822 ! forelimb stylopod [Term] id: UBERON:0004264 name: lower leg skin namespace: uberon def: "A zone of skin that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] synonym: "hind limb middle limb segment skin" EXACT [OBOL:automatic] synonym: "hind limb zeugopod skin" EXACT [OBOL:automatic] xref: EMAPA:18156 xref: MA:0000680 xref: SCTID:244180007 is_a: UBERON:0001511 ! skin of leg intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0003823 ! hindlimb zeugopod [Term] id: UBERON:0004265 name: outflow tract myocardium namespace: uberon def: "A myocardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac muscle of outflow tract" EXACT [OBOL:automatic] synonym: "heart muscle of outflow tract" EXACT [OBOL:automatic] synonym: "heart myocardium of outflow tract" EXACT [OBOL:automatic] synonym: "muscle of heart of outflow tract" EXACT [OBOL:automatic] synonym: "myocardium of outflow tract" EXACT [OBOL:automatic] synonym: "outflow tract cardiac muscle" EXACT [OBOL:automatic] synonym: "outflow tract heart muscle" EXACT [OBOL:automatic] synonym: "outflow tract heart myocardium" EXACT [OBOL:automatic] synonym: "outflow tract muscle of heart" EXACT [OBOL:automatic] xref: EHDAA2:0001358 xref: EMAPA:35623 xref: MA:0000489 xref: VHOG:0000603 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0004145 ! outflow tract relationship: part_of UBERON:0004145 ! outflow tract property_value: UBPROP:0000003 "(...) (theme) is how the vertebrate cardiovascular system differs from that of the presumptive evolutionary chordate ancestor. (...) At best we can tell there are two essential new ingredients: (1) vertebrates all have a continuous endothelial lining to the heart and vessels and (2) vertebrates have developed a second chamber in the heart, one designed for generating high systemic blood pressure.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000603", ontology="VHOG", source="PMID:9187138 Fishman MC, Chien KR, Fashioning the vertebrate heart: earliest embryonic decisions. Development (1997)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004266 name: upper leg connective tissue namespace: uberon def: "A portion of connective tissue that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37325 {source="MA:th"} xref: MA:0000683 is_a: UBERON:0003569 ! leg connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: develops_from UBERON:0005254 ! upper leg mesenchyme relationship: part_of UBERON:0000376 ! hindlimb stylopod relationship: transformation_of UBERON:0005254 ! upper leg mesenchyme [Term] id: UBERON:0004267 name: back connective tissue namespace: uberon def: "A portion of connective tissue that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "mesenchyne of back" RELATED [OBOL:automatic] xref: EMAPA:37256 {source="MA:th"} xref: MA:0000495 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004268 name: lower arm connective tissue namespace: uberon def: "A portion of connective tissue that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37319 {source="MA:th"} xref: MA:0000599 is_a: UBERON:0003573 ! arm connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: develops_from UBERON:0003327 ! mesenchyme of forearm relationship: part_of UBERON:0002386 ! forelimb zeugopod relationship: transformation_of UBERON:0003327 ! mesenchyme of forearm [Term] id: UBERON:0004269 name: upper arm connective tissue namespace: uberon def: "A portion of connective tissue that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37317 {source="MA:th"} xref: MA:0000605 is_a: UBERON:0003573 ! arm connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: develops_from UBERON:0005258 ! upper arm mesenchyme relationship: part_of UBERON:0003822 ! forelimb stylopod relationship: transformation_of UBERON:0005258 ! upper arm mesenchyme [Term] id: UBERON:0004270 name: lower leg connective tissue namespace: uberon def: "A portion of connective tissue that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37327 {source="MA:th"} xref: MA:0000677 is_a: UBERON:0003569 ! leg connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: develops_from UBERON:0005259 ! lower leg mesenchyme relationship: part_of UBERON:0003823 ! hindlimb zeugopod relationship: transformation_of UBERON:0005259 ! lower leg mesenchyme [Term] id: UBERON:0004271 name: outflow tract pericardium namespace: uberon def: "A pericardium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] synonym: "pericardium of outflow tract" EXACT [OBOL:automatic] xref: EMAPA:37707 {source="MA:th"} xref: MA:0000491 is_a: UBERON:0002407 ! pericardium is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002407 ! pericardium intersection_of: part_of UBERON:0004145 ! outflow tract relationship: part_of UBERON:0004145 ! outflow tract [Term] id: UBERON:0004273 name: cartilaginous joint suture namespace: uberon def: "A cranial suture that is part of a cartilaginous joint [Automatically generated definition]." [OBOL:automatic] synonym: "articulatio cartilaginea cranial suture" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea cranial sutures" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea cranial sutures set" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea cranium suture" EXACT [OBOL:automatic] synonym: "articulatio cartilaginea suture of cranium" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranial suture" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranial sutures" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranial sutures set" EXACT [OBOL:automatic] synonym: "cartilaginous joint cranium suture" EXACT [OBOL:automatic] synonym: "cartilaginous joint suture of cranium" EXACT [OBOL:automatic] synonym: "cranial suture of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranial suture of cartilaginous joint" EXACT [OBOL:automatic] synonym: "cranial sutures of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranial sutures of cartilaginous joint" EXACT [OBOL:automatic] synonym: "cranial sutures set of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranial sutures set of cartilaginous joint" EXACT [OBOL:automatic] synonym: "cranium suture of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "cranium suture of cartilaginous joint" EXACT [OBOL:automatic] synonym: "suture of cranium of articulatio cartilaginea" EXACT [OBOL:automatic] synonym: "suture of cranium of cartilaginous joint" EXACT [OBOL:automatic] xref: EMAPA:37463 {source="MA:th"} xref: MA:0001498 is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: part_of UBERON:0002213 ! cartilaginous joint relationship: part_of UBERON:0002213 ! cartilaginous joint [Term] id: UBERON:0004277 name: eye muscle namespace: uberon def: "A muscle that is part of the eye region." [OBOL:automatic] subset: pheno_slim xref: AAO:0000156 xref: EMAPA:35335 xref: MA:0000271 is_a: UBERON:0001630 ! muscle organ is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0000019 {source="MA"} ! camera-type eye [Term] id: UBERON:0004288 name: skeleton namespace: uberon def: "Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body." [VSAO:0000026] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "set of all bones" EXACT [] synonym: "set of bones of body" EXACT [] xref: AEO:0000168 xref: EHDAA2:0001843 xref: EHDAA:5047 xref: EMAPA:17213 xref: FMA:23875 xref: GAID:177 xref: galen:Skeleton xref: MA:0003006 xref: MAT:0000032 xref: MESH:D012863 xref: MIAA:0000032 xref: SCTID:361378004 xref: VSAO:0000026 xref: Wikipedia:Skeleton xref: XAO:0004053 is_a: UBERON:0034925 ! anatomical collection disjoint_from: UBERON:0004770 ! articular system relationship: has_member UBERON:0004765 ! skeletal element relationship: part_of UBERON:0001434 ! skeletal system property_value: RO:0002171 UBERON:0000383 property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/The-skeletal-system" xsd:anyURI property_value: UBPROP:0000001 "Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000026", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"} property_value: UBPROP:0000007 "skeletal" xsd:string [Term] id: UBERON:0004290 name: dermomyotome namespace: uberon def: "The bilaminar epithelium formed from the myotome and dermatome." [AEO:0000214] synonym: "dermamyotome" RELATED [VHOG:0000676] synonym: "dermomyotomes" RELATED PLURAL [VHOG:0000676] xref: AAO:0010572 xref: AEO:0000214 xref: EHDAA2:0003259 xref: EMAPA:31109 xref: FMA:295654 xref: NCIT:C34140 xref: TAO:0001513 xref: UMLS:C1511786 {source="ncithesaurus:Dermomyotome"} xref: VHOG:0000676 xref: ZFA:0001513 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000486 {source="AEO"} ! multilaminar epithelium is_a: UBERON:0016888 {source="AEO"} ! transitional anatomical structure relationship: develops_from UBERON:0002329 {source="EHDAA2", source="ZFA"} ! somite relationship: has_part CL:0000075 ! columnar/cuboidal epithelial cell property_value: UBPROP:0000001 "all but the sclerotome of a mesodermal somite; the primordium of skeletal muscle and, perhaps, of the dermis." xsd:string {source="http://medical-dictionary.thefreedictionary.com/dermomyotome"} property_value: UBPROP:0000001 "Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis. Within the dermomyotome there is also a medio-lateral difference. The central region makes dermis, the mesenchymal connective tissue of the back skin. The medial region (closest to neural tube) makes epaxial muscle, and the lateral region (furthest from neural tube) makes hypaxial muscle[http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768]." xsd:string {source="http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=eurekah&part=A66768"} property_value: UBPROP:0000001 "Epithelial sheet on the external surface of the somite that gives rise to trunk, muscle and dermis.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001513", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Portion of somites that gives rise to dermis and muscles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010572", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000003 "Thus, representatives of the agnathan vertebrates, chondrichthyans, and sarcopterygians all have a layer of undifferentiated cells external to the embryonic myotome. In the amniotes, this external cell layer is the dermomyotome. The simplest interpretation of the similar position, morphology, and lack of myosin labeling is that a dermomyotome epithelium is a shared, ancestral vertebrate characteristic.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000676", ontology="VHOG", source="DOI:10.1111/j.1525-142X.2006.05079.x Devoto SH, Stoiber W, Hammond CL, Steinbacher P, Haslett JR, Barresi MJF, Patterson SE, Adiarte EG and Hughes SM, Generality of vertebrate developmental patterns: evidence for a dermomyotome in fish. Evolution and Development (2006)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004291 name: heart rudiment namespace: uberon def: "A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." [GO:0003313] synonym: "heart cone" EXACT [GO:0003313] synonym: "rudimentary heart" EXACT [ZFA:0000115] xref: TAO:0000115 xref: ZFA:0000115 is_a: UBERON:0012275 ! meso-epithelium relationship: develops_from UBERON:0004139 ! cardiogenic plate property_value: UBPROP:0000001 "The migrating myocardial precursors of the heart rudiment form a cone like structure between 19.5hpf and 22hpf, and eventually telescope out into the primitive heart tube at 24hpf. Stainier 2001.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000115", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0004292 name: cardiac skeleton namespace: uberon def: "Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart." [GO:0003204, Wikipedia:Cardiac_skeleton] synonym: "anulus fibrosus dexter cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "anulus fibrosus sinister cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "cardiac fibrous skeleton" EXACT [EMAPA:36645] synonym: "fibrous skeleton of heart" EXACT [] synonym: "heart fibrous skeleton" EXACT [GO:0003204] synonym: "skeleton of heart" EXACT [FMA:9496] synonym: "trigona fibrosa" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "trigonum fibrosum dextrum cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] synonym: "trigonum fibrosum sinistrum cordis" RELATED LATIN [Wikipedia:Cardiac_skeleton] xref: EMAPA:36645 xref: FMA:9496 xref: Wikipedia:Cardiac_skeleton is_a: UBERON:0003837 ! thoracic segment connective tissue is_a: UBERON:0004120 ! mesoderm-derived structure relationship: adjacent_to UBERON:0002081 ! cardiac atrium relationship: adjacent_to UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0000948 ! heart property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/50/Gray495.png" xsd:anyURI property_value: UBPROP:0000009 "It is not a true skeleton, but it does provide structure and support for the heart, as well as isolating the atria from the ventricles. This allows the AV node and AV bundle to delay the wave of depolarisation such that the atria can contract and assist in ventricular filling before the ventricles themselves depolarise and contract (the AV bundle is the only part of the conduction system that passes from the atria to the ventricles in a normal heart). It also allows the valves (bicuspid, tricuspid, semilunar) to keep open by giving them structural support[WP]" xsd:string [Term] id: UBERON:0004293 name: parasympathetic nerve namespace: uberon def: "A nerve that is part of a parasympathetic nervous system [Automatically generated definition]." [OBOL:automatic] synonym: "nerve of parasympathetic nervous system" EXACT [OBOL:automatic] xref: EHDAA2:0001401 xref: EMAPA:17271 xref: MA:0000224 xref: SCTID:276146002 xref: VHOG:0000641 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000011 ! parasympathetic nervous system relationship: extends_fibers_into UBERON:0001808 ! parasympathetic ganglion relationship: has_developmental_contribution_from UBERON:0005428 {source="NCBIBook:NBK10065"} ! vagal neural crest relationship: has_developmental_contribution_from UBERON:0010075 {source="NCBIBook:NBK10065"} ! sacral neural crest relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000011 ! parasympathetic nervous system [Term] id: UBERON:0004297 name: respiratory system blood vessel smooth muscle namespace: uberon def: "A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "smooth muscle tissue of blood vessel of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37573 {source="MA:th"} xref: MA:0001806 is_a: UBERON:0004225 ! respiratory system smooth muscle is_a: UBERON:0004237 ! blood vessel smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003504 ! respiratory system blood vessel relationship: part_of UBERON:0003504 ! respiratory system blood vessel [Term] id: UBERON:0004300 name: distal phalanx namespace: uberon def: "Distal-most phalanx within a digit." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/120] subset: pheno_slim synonym: "phalanx distalis" EXACT [Wikipedia:Distal_phalanges] synonym: "phalanx distalis" RELATED LATIN [Wikipedia:Distal_phalanges] synonym: "terminal phalanx" EXACT [AAO:0010676] synonym: "ungual phalanx" EXACT [http://www.medilexicon.com/medicaldictionary.php?t=67679] xref: AAO:0010676 xref: EMAPA:35287 xref: MA:0002914 xref: SCTID:299711006 xref: Wikipedia:Distal_phalanges is_a: UBERON:0003221 ! phalanx intersection_of: UBERON:0003221 ! phalanx intersection_of: proximally_connected_to UBERON:0004301 ! middle phalanx relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0009551 ! distal segment of digit relationship: proximally_connected_to UBERON:0004301 ! middle phalanx property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ab/Scheme_human_hand_bones-en.svg" xsd:anyURI property_value: UBPROP:0000008 "In human anatomy, the distal phalanges of the four fingers and toes articulate proximally with the intermediate phalanges at the distal interphalangeal joints (DIP); in the thumb and big toe, with only two phalanges, the distal phalanges articulate proximally with the proximal phalanges. The distal phalanges carry and shape nails and claws and are therefore occasionally referred to as the ungual phalanges. The distal phalanges are cone-shaped in most mammals, including most primates, but relatively wide and flat in humans." xsd:string [Term] id: UBERON:0004301 name: middle phalanx namespace: uberon def: "A phalanx located between proximal and distal phalanges." [http://orcid.org/0000-0002-6601-2165] synonym: "intermediate phalanx" EXACT [] synonym: "medial phalanx" RELATED [] synonym: "penultimate phalanx" RELATED [AAO:0010677] synonym: "phalanx 2" RELATED [] synonym: "phalanx II" RELATED [] xref: AAO:0010677 xref: EMAPA:35572 xref: MA:0002915 xref: SCTID:299710007 xref: Wikipedia:Intermediate_phalanges is_a: UBERON:0003221 ! phalanx intersection_of: UBERON:0003221 ! phalanx intersection_of: distally_connected_to UBERON:0003221 ! phalanx intersection_of: proximally_connected_to UBERON:0003221 ! phalanx relationship: distally_connected_to UBERON:0004300 ! distal phalanx relationship: proximally_connected_to UBERON:0004302 ! proximal phalanx property_value: editor_note "consider using numbering system, and axioms to the effect that there is a single middle phalanx per finger in humans. This should perhaps be renamed 'intermediate phalanx', leaving the term middle phalanx open for the specific intermediate phalanx of a 3-phalanx digit" xsd:string property_value: UBPROP:0000008 "in some groups such as whales, there are multiple intermediate phalanges" xsd:string property_value: UBPROP:0000008 "Intermediate phalanges are bones found in the limbs of most vertebrates. In humans, they are the bones of the finger and toe which lie in the middle, between the two wrinkly joints. The thumb and big toe do not have intermediate phalanges. In most other vertebrates, they have a corresponding place in their limbs, whether they be paw, wing, hoof or fin" xsd:string {source="WP"} [Term] id: UBERON:0004302 name: proximal phalanx namespace: uberon def: "Proximal-most phalanx within a digit." [http://orcid.org/0000-0002-6601-2165] synonym: "phalanx 1" EXACT [] synonym: "phalanx I" EXACT [] synonym: "proximal-most phalanx" EXACT [AAO:0010680] xref: AAO:0010680 xref: EMAPA:35716 xref: MA:0002916 xref: SCTID:299708005 xref: Wikipedia:Proximal_phalanges is_a: UBERON:0003221 ! phalanx intersection_of: UBERON:0003221 ! phalanx intersection_of: connected_to UBERON:0003821 ! metapodium bone relationship: connected_to UBERON:0003821 ! metapodium bone property_value: UBPROP:0000008 "Proximal phalanges are bones found in the limbs of most vertebrates. In humans, they are the bones at the base of a toe or finger, the prominent, knobby ends of which are often called the knuckles. In other vertebrates, proximal phalanges have a similar placement in the corresponding limbs, be they paw, wing or fin. In many species, they are the longest and thickest phalanx ('finger' bone)" xsd:string {source="WP"} property_value: UBPROP:0000105 "1" xsd:nonNegativeInteger [Term] id: UBERON:0004311 name: distal phalanx of manual digit 2 namespace: uberon def: "A distal phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "2nd digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "2nd finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "distal phalanx of index finger" EXACT [FMA:23946] synonym: "distal phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of second digit of hand" EXACT [FMA:23946] synonym: "distal phalanx of second finger" EXACT [OBOL:automatic] synonym: "hand digit 2 distal phalanx" EXACT [OBOL:automatic] synonym: "second distal phalanx of hand" EXACT [FMA:23946] synonym: "second finger distal phalanx" EXACT [OBOL:automatic] xref: FMA:23946 xref: SCTID:361784003 is_a: UBERON:0003636 ! manual digit 2 phalanx is_a: UBERON:0003865 ! distal phalanx of manus is_a: UBERON:0014484 ! distal phalanx of digit 2 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: proximally_connected_to UBERON:0004320 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 2 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004312 name: distal phalanx of manual digit 3 namespace: uberon def: "A distal phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "3rd digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "3rd finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "distal phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of middle finger" EXACT [FMA:23947] synonym: "distal phalanx of third digit of hand" EXACT [FMA:23947] synonym: "distal phalanx of third finger" EXACT [OBOL:automatic] synonym: "equine 3rd phalanx of forelimb digit 3" EXACT [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "equine forelimb distal phalanx" EXACT [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "forelimb coffin bone" NARROW [NCBITaxon:9787] synonym: "forelimb medial claw of artiodactyl" NARROW [NCBITaxon:91561] synonym: "forelimb medial claw of ruminant hoof" NARROW [NCBITaxon:91561] synonym: "forelimb medial ungual phalanx of artiodactyl" NARROW [NCBITaxon:91561] synonym: "forelimb pedal bone" NARROW [NCBITaxon:9787] synonym: "hand digit 3 distal phalanx" EXACT [OBOL:automatic] synonym: "third distal phalanx of hand" EXACT [FMA:23947] synonym: "third finger distal phalanx" EXACT [OBOL:automatic] xref: FMA:23947 xref: SCTID:361786001 xref: SCTID:370674002 is_a: UBERON:0003637 ! manual digit 3 phalanx is_a: UBERON:0003865 ! distal phalanx of manus is_a: UBERON:0014485 ! distal phalanx of digit 3 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: proximally_connected_to UBERON:0004321 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 3 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004313 name: distal phalanx of manual digit 4 namespace: uberon def: "A distal phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "4th digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "4th finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "distal phalanx of fourth digit of hand" EXACT [FMA:23948] synonym: "distal phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "distal phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of ring finger" EXACT [FMA:23948] synonym: "fourth distal phalanx of hand" EXACT [FMA:23948] synonym: "fourth finger distal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 4 distal phalanx" EXACT [OBOL:automatic] xref: FMA:23948 xref: SCTID:361788000 is_a: UBERON:0003638 ! manual digit 4 phalanx is_a: UBERON:0003865 ! distal phalanx of manus is_a: UBERON:0014486 ! distal phalanx of digit 4 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: proximally_connected_to UBERON:0004322 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 4 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004314 name: distal phalanx of manual digit 5 namespace: uberon def: "A distal phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "5th digit of hand distal phalanx" EXACT [OBOL:automatic] synonym: "5th finger distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "distal phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "distal phalanx of fifth digit of hand" EXACT [FMA:23949] synonym: "distal phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "distal phalanx of little finger" EXACT [FMA:23949] synonym: "distal phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "fifth distal phalanx of hand" EXACT [FMA:23949] synonym: "fifth finger distal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 5 distal phalanx" EXACT [OBOL:automatic] xref: FMA:23949 xref: SCTID:361790004 is_a: UBERON:0003639 ! manual digit 5 phalanx is_a: UBERON:0003865 ! distal phalanx of manus is_a: UBERON:0014487 ! distal phalanx of digit 5 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: proximally_connected_to UBERON:0004323 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of manual digit 5 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004315 name: distal phalanx of pedal digit 1 namespace: uberon def: "A distal phalanx that is part of a foot digit 1 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "distal phalanx of big toe" EXACT [FMA:32627] synonym: "distal phalanx of first digit of foot" EXACT [FMA:32627] synonym: "distal phalanx of foot digit 1" EXACT [OBOL:automatic] synonym: "distal phalanx of great toe" EXACT [FMA:32627] synonym: "distal phalanx of hallux" EXACT [OBOL:automatic] synonym: "distal phalanx of pedal digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "first distal phalanx of foot" EXACT [FMA:32627] synonym: "foot digit 1 distal phalanx" EXACT [OBOL:automatic] synonym: "hallux distal phalanx" EXACT [OBOL:automatic] xref: FMA:32627 xref: SCTID:361799003 is_a: UBERON:0003640 ! pedal digit 1 phalanx is_a: UBERON:0003867 ! distal phalanx of pes is_a: UBERON:0014483 ! distal phalanx of digit 1 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: proximally_connected_to UBERON:0004332 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! proximal phalanx of pedal digit 1 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004316 name: distal phalanx of pedal digit 2 namespace: uberon def: "A distal phalanx that is part of a foot digit 2 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "2nd toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "distal phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "distal phalanx of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of second digit of foot" EXACT [FMA:32628] synonym: "distal phalanx of second toe" EXACT [FMA:32628] synonym: "distal phalanx of the 2nd toe" EXACT [OBOL:automatic] synonym: "foot digit 2 distal phalanx" EXACT [OBOL:automatic] synonym: "second distal phalanx of foot" EXACT [FMA:32628] xref: FMA:32628 xref: SCTID:361801000 is_a: UBERON:0003641 ! pedal digit 2 phalanx is_a: UBERON:0003867 ! distal phalanx of pes is_a: UBERON:0014484 ! distal phalanx of digit 2 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: proximally_connected_to UBERON:0004324 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 2 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004317 name: distal phalanx of pedal digit 3 namespace: uberon def: "A distal phalanx that is part of a foot digit 3 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "3rd toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "distal phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "distal phalanx of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of the 3rd toe" EXACT [OBOL:automatic] synonym: "distal phalanx of third digit of foot" EXACT [FMA:32629] synonym: "distal phalanx of third toe" EXACT [FMA:32629] synonym: "equine 3rd phalanx of hindlimb digit 3" EXACT [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "equine hindlimb distal phalanx" EXACT [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "foot digit 3 distal phalanx" EXACT [OBOL:automatic] synonym: "hindlimb coffin bone" NARROW [NCBITaxon:9787] synonym: "hindlimb medial claw of artiodactyl" NARROW [NCBITaxon:91561] synonym: "hindlimb medial claw of ruminant hoof" NARROW [NCBITaxon:91561] synonym: "hindlimb medial ungual phalanx of artiodactyl" NARROW [NCBITaxon:91561] synonym: "hindlimb pedal bone" NARROW [NCBITaxon:9787] synonym: "third distal phalanx of foot" EXACT [FMA:32629] xref: FMA:32629 xref: SCTID:361803002 xref: SCTID:370673008 is_a: UBERON:0003642 ! pedal digit 3 phalanx is_a: UBERON:0003867 ! distal phalanx of pes is_a: UBERON:0014485 ! distal phalanx of digit 3 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: proximally_connected_to UBERON:0004325 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 3 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004318 name: distal phalanx of pedal digit 4 namespace: uberon def: "A distal phalanx that is part of a foot digit 4 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "4th toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "distal phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "distal phalanx of fourth digit of foot" EXACT [FMA:32630] synonym: "distal phalanx of fourth toe" EXACT [FMA:32630] synonym: "distal phalanx of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of the 4th toe" EXACT [OBOL:automatic] synonym: "foot digit 4 distal phalanx" EXACT [OBOL:automatic] synonym: "fourth distal phalanx of foot" EXACT [FMA:32630] xref: FMA:32630 xref: SCTID:361805009 is_a: UBERON:0003862 ! pedal digit 4 phalanx is_a: UBERON:0003867 ! distal phalanx of pes is_a: UBERON:0014486 ! distal phalanx of digit 4 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: proximally_connected_to UBERON:0004326 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 4 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004319 name: distal phalanx of pedal digit 5 namespace: uberon def: "A distal phalanx that is part of a foot digit 5 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "5th toe distal phalanx" EXACT [OBOL:automatic] synonym: "distal phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "distal phalanx of fifth digit of foot" EXACT [FMA:32631] synonym: "distal phalanx of fifth toe" EXACT [FMA:32631] synonym: "distal phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "distal phalanx of little toe" EXACT [FMA:32631] synonym: "distal phalanx of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of the 5th toe" EXACT [OBOL:automatic] synonym: "fifth distal phalanx of foot" EXACT [FMA:32631] synonym: "foot digit 5 distal phalanx" EXACT [OBOL:automatic] xref: FMA:32631 xref: SCTID:10770001 xref: SCTID:244674003 is_a: UBERON:0003863 ! pedal digit 5 phalanx is_a: UBERON:0003867 ! distal phalanx of pes is_a: UBERON:0014487 ! distal phalanx of digit 5 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: proximally_connected_to UBERON:0004327 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! middle phalanx of pedal digit 5 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004320 name: middle phalanx of manual digit 2 namespace: uberon def: "A middle phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "2nd digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "2nd digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "2nd finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "2nd finger middle phalanx" EXACT [OBOL:automatic] synonym: "hand digit 2 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 2 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 2" EXACT [OBOL:automatic] synonym: "intermediate phalanx of second finger" EXACT [OBOL:automatic] synonym: "middle phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "middle phalanx of index finger" EXACT [FMA:23933] synonym: "middle phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of second digit of hand" EXACT [FMA:23933] synonym: "middle phalanx of second finger" EXACT [OBOL:automatic] synonym: "second finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "second finger middle phalanx" EXACT [OBOL:automatic] synonym: "second middle phalanx of hand" EXACT [FMA:23933] xref: FMA:23933 xref: SCTID:263407002 is_a: UBERON:0003636 ! manual digit 2 phalanx is_a: UBERON:0003864 ! middle phalanx of manus is_a: UBERON:0014488 ! middle phalanx of digit 2 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: distally_connected_to UBERON:0004311 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of manual digit 2 relationship: proximally_connected_to UBERON:0004328 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of manual digit 2 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004321 name: middle phalanx of manual digit 3 namespace: uberon def: "A middle phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "3rd digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "3rd digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "3rd finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "3rd finger middle phalanx" EXACT [OBOL:automatic] synonym: "forelimb digit III P2" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "forelimb short pastern bone" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "hand digit 3 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 3 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 3" EXACT [OBOL:automatic] synonym: "intermediate phalanx of third finger" EXACT [OBOL:automatic] synonym: "middle phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "middle phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of middle finger" EXACT [OBOL:automatic] synonym: "middle phalanx of third digit of hand" EXACT [FMA:23934] synonym: "middle phalanx of third finger" EXACT [OBOL:automatic] synonym: "third finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "third finger middle phalanx" EXACT [OBOL:automatic] synonym: "third middle phalanx of hand" EXACT [FMA:23934] xref: FMA:23934 xref: SCTID:263408007 xref: SCTID:370729003 is_a: UBERON:0003637 ! manual digit 3 phalanx is_a: UBERON:0003864 ! middle phalanx of manus is_a: UBERON:0014489 ! middle phalanx of digit 3 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: distally_connected_to UBERON:0004312 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of manual digit 3 relationship: proximally_connected_to UBERON:0004329 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of manual digit 3 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004322 name: middle phalanx of manual digit 4 namespace: uberon def: "A middle phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "4th digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "4th digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "4th finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "4th finger middle phalanx" EXACT [OBOL:automatic] synonym: "fourth finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "fourth finger middle phalanx" EXACT [OBOL:automatic] synonym: "fourth middle phalanx of hand" EXACT [FMA:23935] synonym: "hand digit 4 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 4 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 4" EXACT [OBOL:automatic] synonym: "middle phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "middle phalanx of fourth digit of hand" EXACT [FMA:23935] synonym: "middle phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "middle phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of ring finger" EXACT [OBOL:automatic] xref: FMA:23935 xref: SCTID:263409004 is_a: UBERON:0003638 ! manual digit 4 phalanx is_a: UBERON:0003864 ! middle phalanx of manus is_a: UBERON:0014490 ! middle phalanx of digit 4 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: distally_connected_to UBERON:0004313 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of manual digit 4 relationship: proximally_connected_to UBERON:0004330 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of manual digit 4 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004323 name: middle phalanx of manual digit 5 namespace: uberon def: "A middle phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "5th digit of hand intermediate phalanx" EXACT [OBOL:automatic] synonym: "5th digit of hand middle phalanx" EXACT [OBOL:automatic] synonym: "5th finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "5th finger middle phalanx" EXACT [OBOL:automatic] synonym: "fifth finger intermediate phalanx" EXACT [OBOL:automatic] synonym: "fifth finger middle phalanx" EXACT [OBOL:automatic] synonym: "fifth middle phalanx of hand" EXACT [FMA:23936] synonym: "hand digit 5 intermediate phalanx" EXACT [OBOL:automatic] synonym: "hand digit 5 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "intermediate phalanx of hand digit 5" EXACT [OBOL:automatic] synonym: "middle phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "middle phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "middle phalanx of fifth digit of hand" EXACT [FMA:23936] synonym: "middle phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "middle phalanx of little finger" EXACT [OBOL:automatic] synonym: "middle phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:23936 xref: SCTID:263410009 is_a: UBERON:0003639 ! manual digit 5 phalanx is_a: UBERON:0003864 ! middle phalanx of manus is_a: UBERON:0014491 ! middle phalanx of digit 5 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: distally_connected_to UBERON:0004314 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of manual digit 5 relationship: proximally_connected_to UBERON:0004331 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of manual digit 5 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004324 name: middle phalanx of pedal digit 2 namespace: uberon def: "A middle phalanx that is part of a foot digit 2 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "2nd toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "2nd toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 2 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 2 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "middle phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "middle phalanx of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of second digit of foot" EXACT [FMA:32623] synonym: "middle phalanx of second toe" EXACT [FMA:32623] synonym: "middle phalanx of the 2nd toe" EXACT [OBOL:automatic] synonym: "second middle phalanx of foot" EXACT [FMA:32623] xref: FMA:32623 xref: SCTID:182152006 is_a: UBERON:0003641 ! pedal digit 2 phalanx is_a: UBERON:0003866 ! middle phalanx of pes is_a: UBERON:0014488 ! middle phalanx of digit 2 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: distally_connected_to UBERON:0004316 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of pedal digit 2 relationship: proximally_connected_to UBERON:0004333 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of pedal digit 2 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004325 name: middle phalanx of pedal digit 3 namespace: uberon def: "A middle phalanx that is part of a foot digit 3 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "3rd toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "3rd toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 3 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 3 middle phalanx" EXACT [OBOL:automatic] synonym: "hindlimb digit III P2" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "hindlimb short pastern bone" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "intermediate phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "middle phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "middle phalanx of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of the 3rd toe" EXACT [OBOL:automatic] synonym: "middle phalanx of third digit of foot" EXACT [FMA:32624] synonym: "middle phalanx of third toe" EXACT [FMA:32624] synonym: "third middle phalanx of foot" EXACT [FMA:32624] xref: FMA:32624 xref: SCTID:182154007 xref: SCTID:370677009 is_a: UBERON:0003642 ! pedal digit 3 phalanx is_a: UBERON:0003866 ! middle phalanx of pes is_a: UBERON:0014489 ! middle phalanx of digit 3 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: distally_connected_to UBERON:0004317 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of pedal digit 3 relationship: proximally_connected_to UBERON:0004334 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of pedal digit 3 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004326 name: middle phalanx of pedal digit 4 namespace: uberon def: "A middle phalanx that is part of a pedal digit 4 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "4th toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "4th toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 4 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 4 middle phalanx" EXACT [OBOL:automatic] synonym: "fourth middle phalanx of foot" EXACT [FMA:32625] synonym: "intermediate phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "middle phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "middle phalanx of fourth digit of foot" EXACT [FMA:32625] synonym: "middle phalanx of fourth toe" EXACT [OBOL:automatic] synonym: "middle phalanx of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of the 4th toe" EXACT [OBOL:automatic] xref: FMA:32625 xref: SCTID:182156009 is_a: UBERON:0003862 ! pedal digit 4 phalanx is_a: UBERON:0003866 ! middle phalanx of pes is_a: UBERON:0014490 ! middle phalanx of digit 4 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: distally_connected_to UBERON:0004318 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of pedal digit 4 relationship: proximally_connected_to UBERON:0004335 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of pedal digit 4 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004327 name: middle phalanx of pedal digit 5 namespace: uberon def: "A middle phalanx that is part of a pedal digit 5 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "5th toe intermediate phalanx" EXACT [OBOL:automatic] synonym: "5th toe middle phalanx" EXACT [OBOL:automatic] synonym: "foot digit 5 intermediate phalanx" EXACT [OBOL:automatic] synonym: "foot digit 5 middle phalanx" EXACT [OBOL:automatic] synonym: "intermediate phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "intermediate phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "middle phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "middle phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "middle phalanx of little toe" EXACT [OBOL:automatic] synonym: "middle phalanx of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of the 5th toe" EXACT [OBOL:automatic] xref: FMA:230984 xref: SCTID:182158005 xref: SCTID:244673009 is_a: UBERON:0003863 ! pedal digit 5 phalanx is_a: UBERON:0003866 ! middle phalanx of pes is_a: UBERON:0014491 ! middle phalanx of digit 5 intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: distally_connected_to UBERON:0004319 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! distal phalanx of pedal digit 5 relationship: proximally_connected_to UBERON:0004336 {gci_filler="NCBITaxon:314146", gci_relation="part_of", source="shoge-lite"} ! proximal phalanx of pedal digit 5 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004328 name: proximal phalanx of manual digit 2 namespace: uberon def: "A proximal phalanx that is part of a hand digit 2 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "2nd digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "2nd finger proximal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 2 proximal phalanx" EXACT [OBOL:automatic] synonym: "manual digit 2 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "manual phalanx II-1" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 2nd digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 2nd finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of index finger" EXACT [FMA:23919] synonym: "proximal phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of second digit of hand" EXACT [FMA:23919] synonym: "proximal phalanx of second finger" EXACT [OBOL:automatic] synonym: "second finger proximal phalanx" EXACT [OBOL:automatic] synonym: "second proximal phalanx of hand" EXACT [FMA:23919] xref: FMA:23919 xref: SCTID:263403003 is_a: UBERON:0002234 ! proximal phalanx of manus is_a: UBERON:0003636 ! manual digit 2 phalanx is_a: UBERON:0014502 ! proximal phalanx of digit 2 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: proximally_connected_to UBERON:0003646 ! metacarpal bone of digit 2 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004329 name: proximal phalanx of manual digit 3 namespace: uberon def: "A proximal phalanx that is part of a hand digit 3 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "3rd digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "3rd finger proximal phalanx" EXACT [OBOL:automatic] synonym: "hand digit 3 proximal phalanx" EXACT [OBOL:automatic] synonym: "manual digit 3 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "manual phalanx III-1" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 3rd digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 3rd finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of middle finger" EXACT [FMA:23920] synonym: "proximal phalanx of third digit of hand" EXACT [FMA:23920] synonym: "proximal phalanx of third finger" EXACT [OBOL:automatic] synonym: "third finger proximal phalanx" EXACT [OBOL:automatic] synonym: "third proximal phalanx of hand" EXACT [FMA:23920] xref: FMA:23920 xref: SCTID:263404009 xref: SCTID:370735003 is_a: UBERON:0002234 ! proximal phalanx of manus is_a: UBERON:0003637 ! manual digit 3 phalanx is_a: UBERON:0014503 ! proximal phalanx of digit 3 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: proximally_connected_to UBERON:0003647 ! metacarpal bone of digit 3 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004330 name: proximal phalanx of manual digit 4 namespace: uberon def: "A proximal phalanx that is part of a hand digit 4 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "4th digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "4th finger proximal phalanx" EXACT [OBOL:automatic] synonym: "fourth finger proximal phalanx" EXACT [OBOL:automatic] synonym: "fourth proximal phalanx of hand" EXACT [FMA:23921] synonym: "hand digit 4 proximal phalanx" EXACT [OBOL:automatic] synonym: "manual digit 4 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "manual phalanx IV-1" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 4th digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 4th finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of fourth digit of hand" EXACT [FMA:23921] synonym: "proximal phalanx of fourth finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of ring finger" EXACT [FMA:23921] xref: FMA:23921 xref: SCTID:263405005 is_a: UBERON:0002234 ! proximal phalanx of manus is_a: UBERON:0003638 ! manual digit 4 phalanx is_a: UBERON:0014504 ! proximal phalanx of digit 4 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: proximally_connected_to UBERON:0003648 ! metacarpal bone of digit 4 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004331 name: proximal phalanx of manual digit 5 namespace: uberon def: "A proximal phalanx that is part of a hand digit 5 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "5th digit of hand proximal phalanx" EXACT [OBOL:automatic] synonym: "5th finger proximal phalanx" EXACT [OBOL:automatic] synonym: "fifth finger proximal phalanx" EXACT [OBOL:automatic] synonym: "fifth proximal phalanx of hand" EXACT [FMA:23922] synonym: "hand digit 5 proximal phalanx" EXACT [OBOL:automatic] synonym: "manual digit 5 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "manual phalanx V-1" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 5th digit of hand" EXACT [OBOL:automatic] synonym: "proximal phalanx of 5th finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of fifth digit of hand" EXACT [FMA:23922] synonym: "proximal phalanx of fifth finger" EXACT [OBOL:automatic] synonym: "proximal phalanx of little finger" EXACT [FMA:23922] synonym: "proximal phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:23922 xref: SCTID:263406006 is_a: UBERON:0002234 ! proximal phalanx of manus is_a: UBERON:0003639 ! manual digit 5 phalanx is_a: UBERON:0014505 ! proximal phalanx of digit 5 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: proximally_connected_to UBERON:0003649 ! metacarpal bone of digit 5 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004332 name: proximal phalanx of pedal digit 1 namespace: uberon def: "A proximal phalanx that is part of a pedal digit 1 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "foot digit 1 proximal phalanx" EXACT [OBOL:automatic] synonym: "hallux proximal phalanx" EXACT [OBOL:automatic] synonym: "pedal phalanx I-1" EXACT [PHENOSCAPE:wd] synonym: "predal digit 1 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of big toe" EXACT [FMA:43252] synonym: "proximal phalanx of foot digit 1" EXACT [OBOL:automatic] synonym: "proximal phalanx of great toe" EXACT [FMA:43252] synonym: "proximal phalanx of hallux" EXACT [OBOL:automatic] synonym: "proximal phalanx of pedal digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of the 1st toe" EXACT [] xref: FMA:43252 xref: SCTID:182150003 is_a: UBERON:0003640 ! pedal digit 1 phalanx is_a: UBERON:0003868 ! proximal phalanx of pes is_a: UBERON:0014501 ! proximal phalanx of digit 1 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: proximally_connected_to UBERON:0003650 ! metatarsal bone of digit 1 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004333 name: proximal phalanx of pedal digit 2 namespace: uberon def: "A proximal phalanx that is part of a pedal digit 2 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "2nd toe proximal phalanx" EXACT [OBOL:automatic] synonym: "foot digit 2 proximal phalanx" EXACT [OBOL:automatic] synonym: "pedal phalanx II-1" EXACT [PHENOSCAPE:wd] synonym: "predal digit 2 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 2nd toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 2" EXACT [OBOL:automatic] synonym: "proximal phalanx of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of second digit of foot" EXACT [FMA:32618] synonym: "proximal phalanx of second toe" EXACT [FMA:32618] synonym: "proximal phalanx of the 2nd toe" EXACT [] synonym: "second proximal phalanx of foot" EXACT [FMA:32618] xref: FMA:32618 xref: SCTID:182151004 is_a: UBERON:0003641 ! pedal digit 2 phalanx is_a: UBERON:0003868 ! proximal phalanx of pes is_a: UBERON:0014502 ! proximal phalanx of digit 2 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: proximally_connected_to UBERON:0003651 ! metatarsal bone of digit 2 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004334 name: proximal phalanx of pedal digit 3 namespace: uberon def: "A proximal phalanx that is part of a pedal digit 3 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "3rd toe proximal phalanx" EXACT [OBOL:automatic] synonym: "foot digit 3 proximal phalanx" EXACT [OBOL:automatic] synonym: "pedal phalanx III-1" EXACT [PHENOSCAPE:wd] synonym: "predal digit 3 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 3rd toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 3" EXACT [OBOL:automatic] synonym: "proximal phalanx of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of the 3rd toe" EXACT [] synonym: "proximal phalanx of third digit of foot" EXACT [FMA:32619] synonym: "proximal phalanx of third toe" EXACT [FMA:32619] synonym: "third proximal phalanx of foot" EXACT [FMA:32619] xref: FMA:32619 xref: SCTID:182153001 xref: SCTID:370734004 is_a: UBERON:0003642 ! pedal digit 3 phalanx is_a: UBERON:0003868 ! proximal phalanx of pes is_a: UBERON:0014503 ! proximal phalanx of digit 3 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: proximally_connected_to UBERON:0003652 ! metatarsal bone of digit 3 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004335 name: proximal phalanx of pedal digit 4 namespace: uberon def: "A proximal phalanx that is part of a pedal digit 4 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "4th toe proximal phalanx" EXACT [OBOL:automatic] synonym: "foot digit 4 proximal phalanx" EXACT [OBOL:automatic] synonym: "fourth proximal phalanx of foot" EXACT [FMA:32620] synonym: "pedal phalanx IV-1" EXACT [PHENOSCAPE:wd] synonym: "predal digit 4 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 4th toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of foot digit 4" EXACT [OBOL:automatic] synonym: "proximal phalanx of fourth digit of foot" EXACT [FMA:32620] synonym: "proximal phalanx of fourth toe" EXACT [FMA:32620] synonym: "proximal phalanx of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of the 4th toe" EXACT [] xref: FMA:32620 xref: SCTID:182155008 is_a: UBERON:0003862 ! pedal digit 4 phalanx is_a: UBERON:0003868 ! proximal phalanx of pes is_a: UBERON:0014504 ! proximal phalanx of digit 4 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: proximally_connected_to UBERON:0003653 ! metatarsal bone of digit 4 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004336 name: proximal phalanx of pedal digit 5 namespace: uberon def: "A proximal phalanx that is part of a pedal digit 5 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "5th toe proximal phalanx" EXACT [OBOL:automatic] synonym: "fifth proximal phalanx of foot" EXACT [FMA:32621] synonym: "foot digit 5 proximal phalanx" EXACT [OBOL:automatic] synonym: "pedal phalanx V-1" EXACT [PHENOSCAPE:wd] synonym: "predal digit 5 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 5th toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of fifth digit of foot" EXACT [FMA:32621] synonym: "proximal phalanx of fifth toe" EXACT [FMA:32621] synonym: "proximal phalanx of foot digit 5" EXACT [OBOL:automatic] synonym: "proximal phalanx of little toe" EXACT [OBOL:automatic] synonym: "proximal phalanx of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of the 5th toe" EXACT [] xref: FMA:32621 xref: SCTID:182157000 xref: SCTID:244672004 is_a: UBERON:0003863 ! pedal digit 5 phalanx is_a: UBERON:0003868 ! proximal phalanx of pes is_a: UBERON:0014505 ! proximal phalanx of digit 5 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: proximally_connected_to UBERON:0003654 ! metatarsal bone of digit 5 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004337 name: distal phalanx of manual digit 1 namespace: uberon def: "A distal phalanx that is part of a hand digit 1 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "distal phalanx of first digit of hand" EXACT [FMA:23945] synonym: "distal phalanx of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of thumb" EXACT [OBOL:automatic] synonym: "first distal phalanx of hand" EXACT [FMA:23945] synonym: "manual digit 1 distal phalanx" EXACT [PHENOSCAPE:wd] synonym: "PDP" EXACT [Wikipedia:Distal_phalanges#Thumb] synonym: "pollical distal phalanx" EXACT [Wikipedia:Distal_phalanges#Thumb] synonym: "thumb distal phalanx" EXACT [OBOL:automatic] xref: FMA:23945 xref: SCTID:182007006 is_a: UBERON:0003620 ! manual digit 1 phalanx is_a: UBERON:0003865 ! distal phalanx of manus is_a: UBERON:0014483 ! distal phalanx of digit 1 intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: proximally_connected_to UBERON:0004338 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="shoge-lite"} ! proximal phalanx of manual digit 1 property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "The human pollical distal phalanx (PDP) has a pronounced insertion for the flexor pollicis longus (asymmetric towards the radial side), an ungual fossa, and a pair of dissymmetric ungual spines (the ulnar being more prominent). This asymmetry is necessary to ensure that the thumb pulp is always facing the pulps of the other digits, an osteological configuration which provides the maximum contact surface with held objects." xsd:string {source="WP"} [Term] id: UBERON:0004338 name: proximal phalanx of manual digit 1 namespace: uberon def: "A proximal phalanx that is part of a hand digit 1 [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "first proximal phalanx of hand" EXACT [FMA:23918] synonym: "manual digit 1 proximal phalanx" EXACT [PHENOSCAPE:wd] synonym: "manual phalanx I-1" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of first digit of hand" EXACT [FMA:23918] synonym: "proximal phalanx of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of thumb" EXACT [OBOL:automatic] synonym: "thumb proximal" EXACT [OBOL:automatic] xref: FMA:23918 xref: SCTID:181992006 is_a: UBERON:0002234 ! proximal phalanx of manus is_a: UBERON:0003620 ! manual digit 1 phalanx is_a: UBERON:0014501 ! proximal phalanx of digit 1 intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: proximally_connected_to UBERON:0003645 ! metacarpal bone of digit 1 property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004339 name: vault of skull namespace: uberon def: "Upper part of skull, consisting of parietals, frontals, post-parietals, and in some species the squamosal and a portion of the alisphenoid." [MP:0000076, PMID:11523816, Wikipedia:Calvaria_(skull)] comment: Terminology notes. we include calvarium as a synonym, but Gray's Anatomy's list includes the Ethmoid and Sphenoid bone in the Calvaria. Some books (and HPO) state that calvaria consists of just the frontal bone, parietal bone, temporal bone, and occipital bone. Note vault may not be precisely equivalent to calvaria subset: pheno_slim synonym: "calva" EXACT [FMA:52800] synonym: "calvaria" RELATED PLURAL [ZFA:0005606] synonym: "calvarium" RELATED [] synonym: "cranial vault" EXACT [ZFA:0005606] synonym: "skull roof" NARROW [] synonym: "skull vault" EXACT [] synonym: "skullcap" RELATED [ZFA:0005606] xref: EHDAA2:0002167 xref: EHDAA:9538 xref: EMAPA:18016 xref: FMA:52800 xref: NCIT:C81188 xref: SCTID:140592008 xref: UMLS:C0205950 {source="ncithesaurus:Skullcap"} xref: VHOG:0000331 xref: Wikipedia:Calvaria_(skull) xref: ZFA:0005606 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010912 ! subdivision of skeleton relationship: contributes_to_morphology_of UBERON:0003128 ! cranium relationship: overlaps UBERON:0003113 {notes="small pharyngeal arch and sclerotomal contribution"} ! dermatocranium relationship: part_of UBERON:0001703 ! neurocranium property_value: editor_note "We follow http://www.ncbi.nlm.nih.gov/pubmed/11523816 (Morriss-Kay) in definingenumerating the components of the skull vault. Note that there is a conflict with Kardong; e.g. in fig 7.10, Kardong places the squamosal in the temporal series. We cannot place the vault as entirely part of the dermatocranium as it has a small splanchnocranium contribution and a sclerotomal contribution" xsd:string property_value: UBPROP:0000003 "The earliest tetrapods arose from rhipidistian ancestors and retained many of their skull features, including most of the bones of the dermatocranium.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000331", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.256", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004340 name: allantois namespace: uberon def: "A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]." [VHOG:0000738, Wikipedia:Allantois] subset: pheno_slim synonym: "allantoic bud" RELATED [EMAPA:16107] xref: BTO:0000474 xref: EHDAA2:0001504 xref: EMAPA:16107 xref: EMAPA_RETIRED:16084 xref: MESH:D000482 xref: NCIT:C34101 xref: RETIRED_EHDAA2:0000114 xref: SCTID:308825007 xref: UMLS:C0002084 {source="ncithesaurus:Allantois"} xref: VHOG:0000738 xref: Wikipedia:Allantois is_a: UBERON:0005631 ! extraembryonic membrane relationship: develops_from UBERON:0000162 {source="Hymans"} ! cloaca relationship: has_developmental_contribution_from UBERON:0000925 {notes="hindgut diverticulum endoderm", source="ISBN:0073040584"} ! endoderm relationship: has_developmental_contribution_from UBERON:0004872 {source="ISBN:0073040584"} ! splanchnic layer of lateral plate mesoderm relationship: only_in_taxon NCBITaxon:32524 {source="Hymans"} ! Amniota relationship: overlaps UBERON:0001008 {source="EHDAA2-modified"} ! renal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a5/Gray25.png" xsd:anyURI property_value: UBPROP:0000001 "A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000738", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/allantois"} property_value: UBPROP:0000003 "Structures homologous to the four extraembryonic membranes of reptiles and birds appear in mammals: amnion, chorion, yolk sac, and allantois.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000738", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.187", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "allantoic" xsd:string property_value: UBPROP:0000011 "a diverticulum of the hindgut endoderm [ISBN:0073040584 (Vertebrates, Kardong)]" xsd:string property_value: UBPROP:0000012 "part_of embryo in EHDAA2 - note differences in humans" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0004341 name: primitive streak namespace: uberon def: "The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP]." [MP:0002231, Wikipedia:Primitive_streak] subset: early_development subset: pheno_slim synonym: "primitive streak - blastopore - germ ring" EXACT [VHOG:0001202] xref: EHDAA2:0001525 xref: EHDAA:185 xref: EMAPA:16072 xref: FMA:293110 xref: MESH:D054240 xref: NCIT:C28402 xref: SCTID:361438007 xref: UMLS:C0033153 {source="ncithesaurus:Primitive_Streak"} xref: VHOG:0001202 xref: Wikipedia:Primitive_streak is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000485 {source="EHDAA2"} ! simple columnar epithelium is_a: UBERON:0005291 ! embryonic tissue relationship: develops_from UBERON:0008780 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="ISBN:9780878932504"} ! inner cell mass derived epiblast relationship: has_potential_to_develop_into UBERON:0000925 ! endoderm relationship: has_potential_to_develop_into UBERON:0000926 ! mesoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f4/Gray13.png" xsd:anyURI property_value: RO:0002174 NCBITaxon:32443 property_value: UBPROP:0000003 "(...) the blastopore equivalent of chordates (germ ring in fish, marginal zone/blastopore lip in frog and node/primitive streak in chick and mouse) (...) (reference 1); Indeed, the primitive streak has been considered the homologue of the blastopore since the 1870s (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001202", ontology="VHOG", source="PMID:9609826 Wu LH, Lengyel JA, Role of caudal in hindgut specification and gastrulation suggests homology between Drosophila amnioproctodeal invagination and vertebrate blastopore. Development (1998), ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.139", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "VHOG includes a very broad grouping here based on http://www.ncbi.nlm.nih.gov/pubmed/9609826" xsd:string {external_ontology="VHOG"} [Term] id: UBERON:0004345 name: trophectoderm namespace: uberon def: "Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition." [MP:0005028] subset: early_development subset: pheno_slim xref: BTO:0001840 xref: EHDAA2:0002091 xref: EHDAA:56 xref: EMAPA:16046 xref: VHOG:0000979 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005292 ! extraembryonic tissue relationship: develops_from UBERON:0000085 {source="EHDAA2"} ! morula relationship: has_part CL:1000274 ! trophectodermal cell relationship: part_of UBERON:0005631 {source="EHDAA2"} ! extraembryonic membrane property_value: editor_note "distinction between trophectoderm and trophoblast unclear/inconsistent in many sources" xsd:string property_value: UBPROP:0000001 "The outer cellular layer of the mammalian blastocyst. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.750, see_Kardong_KV][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000979", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "(...) the trophoblast develops rapidly so that contact may be made with the maternal uterine tissues when conditions are appropriate. We have here an excellent example of an embryonic adaptation, the development of a structure never present in either adult or embryo of 'lower' vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000979", ontology="VHOG", source="ISBN:978-0721676685 Romer AS, Parsons TS, Vertebrate body (1977) p.105-106", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "trophectodermal" xsd:string property_value: UBPROP:0000012 "BTO has this has part of the trophoblast" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0004347 name: limb bud namespace: uberon def: "An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." [https://orcid.org/0000-0002-6601-2165, ISBN:9780878932504, MP:0005650, Wikipedia:Limb_bud] comment: developmentally_induced_by Fgf10, capable of initiating limb forming interactions between endoderm and mesoderm subset: pheno_slim synonym: "gemmae membrorum" RELATED LATIN [Wikipedia:Limb_bud] synonym: "limb buds" EXACT PLURAL [] synonym: "limbbud" EXACT [GO:0060174] xref: AAO:0010375 xref: BTO:0001640 xref: EMAPA:35944 xref: FMA:296780 xref: GAID:1307 xref: MESH:D018878 xref: NCIT:C34203 xref: UMLS:C0282505 {source="ncithesaurus:Limb_Bud"} xref: Wikipedia:Limb_bud xref: XAO:0003161 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004357 ! paired limb/fin bud relationship: developmentally_induced_by UBERON:0003081 {source="ISBN:9780878932504"} ! lateral plate mesoderm relationship: has_developmental_contribution_from UBERON:0005733 ! limb field relationship: has_potential_to_develop_into UBERON:0002101 ! limb relationship: only_in_taxon NCBITaxon:32523 ! Tetrapoda property_value: UBPROP:0000001 "Early outgrowth of presumptive limb.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010375", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0004348 name: optic eminence namespace: uberon def: "The embryonic structure that gives rise to the corneal ectoderm." [MP:0006305] subset: pheno_slim xref: EHDAA:938 xref: EMAPA:16322 xref: RETIRED_EHDAA2:0001308 xref: VHOG:0001296 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0000964 ! cornea [Term] id: UBERON:0004356 name: apical ectodermal ridge namespace: uberon def: "Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]." [MP:0001676, Wikipedia:Apical_ectodermal_ridge] subset: pheno_slim synonym: "AER" RELATED [MP:0001676] synonym: "apical epidermal ridge" EXACT [XAO:0004121] synonym: "crista ectodermalis apicalis" RELATED LATIN [Wikipedia:Apical_ectodermal_ridge] xref: AAO:0010760 xref: EMAPA:32744 xref: NCIT:C34109 xref: TAO:0002146 xref: UMLS:C1516037 {source="ncithesaurus:Apical_Ectodermal_Ridge"} xref: Wikipedia:Apical_ectodermal_ridge xref: XAO:0004121 xref: ZFA:0001702 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0002050 ! embryonic structure relationship: capable_of GO:0010464 ! regulation of mesenchymal cell proliferation relationship: capable_of GO:0061037 ! negative regulation of cartilage development relationship: developmentally_induced_by UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0000924 ! ectoderm relationship: part_of UBERON:0004357 ! paired limb/fin bud relationship: produces PR:000007499 ! fibroblast growth factor 8 property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/56/Limbbuddiagram.jpg" xsd:anyURI property_value: IAO:0000232 "note that media, dorsal fins etc have AERs." xsd:string property_value: UBPROP:0000001 "Distal ectodermal thickening which forms along the anterior-posterior limb axis. Signaling from this region influences proximal-distal patterning of the limb. Structure is missing in some lineages (salamanders, Eleutherodactylus coqui) however morphologically their indistinct distal ectoderm may still be involved in signaling.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010760", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Proliferative region that is part of the developing fin fold or fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002146", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: subclass proliferative region (TAO:0000098)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002146", ontology="TAO"} property_value: UBPROP:0000008 "The AER of tetrapods regresses after specification of skeletal progenitors, the AER of teleosts form an elongating fin fold" xsd:string {source="PMID:20574421"} property_value: UBPROP:0000009 "maintaining mesenchyme in plastic proliferating state; maintaining expression of A-P axis genes; interacting with D-V proteins. Genes: AER induced by Fgf10 in mesenchyme. AER secretes Fgf8, which stimulates mitosis in the mesenchyme causing Fgf10 production - positive feedback loop" xsd:string [Term] id: UBERON:0004357 name: paired limb/fin bud namespace: uberon def: "An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]." [https://orcid.org/0000-0002-6601-2165, ISBN:9780878932504, MP:0005650] comment: Genes: In limb buds of chick and mouse, Shh expression is activated as soon as there is a morphological bud, whereas in S. canicula fin buds, consistent with reported data in other cartilaginous fishes, Shh is transcribed late in fin development[PMID:17187056] subset: homology_grouping synonym: "limb - fin bud" EXACT [VHOG:0001258] synonym: "paired appendage bud" EXACT [] synonym: "paired limb/fin bud" EXACT [VHOG:0001258] xref: VHOG:0001258 is_a: UBERON:0003102 ! surface structure is_a: UBERON:0006598 ! presumptive structure relationship: has_developmental_contribution_from UBERON:0005732 ! paired limb/fin field relationship: has_part UBERON:0004356 ! apical ectodermal ridge relationship: has_potential_to_develop_into UBERON:0004708 ! paired limb/fin property_value: UBPROP:0000003 "The tetrapod limb is derived from a posterior part of the fin endoskeleton of elasmobranchs and basal bony fish, the so-called metapterygium, a series of endoskeletal elements that is the first to form in the developing paired fins. (...) In addition, there is an independent endoskeletal element called the protopterygium that develops anterior to the metapterygium in many basal fishes (e.g., the bichir and sturgeon). Teleosts have lost the metapterygium whereas the sarcopterygians, on the other hand, have lost the protopterygium. Sarcopterygians thus develop all their endoskeletal structures from the metapterygium and consequently the tetrapod limb skeleton is derived from the metapterygium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001258", ontology="VHOG", source="DOI:10.1002/jez.1100 Wagner GP, Chiu C, The tetrapod limb: A hypothesis on its origin. J Exp Zool (Mol Dev Evol) (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004362 name: pharyngeal arch 1 namespace: uberon def: "The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "1st arch" RELATED [EHDAA2:0000006] synonym: "1st pharyngeal arch" EXACT [] synonym: "1st visceral arch" RELATED [VHOG:0000296] synonym: "arcus pharyngeus primus" RELATED LATIN [Wikipedia:First_pharyngeal_arch] synonym: "branchial arch 1" EXACT SENSU [] synonym: "first branchial arch" EXACT SENSU [] synonym: "first pharyngeal arch" EXACT [] synonym: "first visceral arch" EXACT SENSU [] synonym: "mandibular arch" EXACT [] synonym: "visceral arch 1" EXACT SENSU [] xref: AAO:0010364 xref: CALOHA:TS-2089 xref: EHDAA2:0000006 xref: EHDAA:573 xref: EMAPA:16118 xref: FMA:293019 xref: MFMO:0000095 xref: NCIT:C34175 xref: SCTID:308767008 xref: TAO:0001595 xref: UMLS:C1517197 {source="ncithesaurus:First_Pharyngeal_Arch"} xref: VHOG:0000296 xref: Wikipedia:First_pharyngeal_arch xref: XAO:0000097 xref: ZFA:0001612 is_a: UBERON:0002539 ! pharyngeal arch property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray48.png" xsd:anyURI property_value: UBPROP:0000001 "the first arch which contributes to development of mastication muscles, maxilla, mandible, incus, malleus, Meckel's cartilage, trigeminal nerve, and maxillary artery" xsd:string {source="MP:0006337,MGI:smb"} property_value: UBPROP:0000001 "The first of the series of bony or cartilaginous arches that develop in the walls of the mouth cavity and pharynx of the embryo.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010364", ontology="AAO", source="XAO:EJS"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000296", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000103 "1" xsd:nonNegativeInteger [Term] id: UBERON:0004363 name: pharyngeal arch artery namespace: uberon alt_id: UBERON:0004342 def: "One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP]." [MP:0002672] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "a. arcuum pharyngeorum" RELATED LATIN [Wikipedia:Aortic_arches] synonym: "aortic arch" EXACT [ZFA:0005004] synonym: "aortic arch artery" RELATED [EMAPA:16684] synonym: "aortic arches" EXACT PLURAL [ZFA:0005004] synonym: "arteriae arcuum pharyngeorum" RELATED LATIN [Wikipedia:Aortic_arches] synonym: "branchial aortic arches" EXACT PLURAL [ZFIN:ZDB-PUB-080512-6] synonym: "branchial aortic arches" RELATED PLURAL [ZFA:0005004, ZFIN:ZDB-PUB-080512-6] synonym: "branchial arch artery" EXACT [EMAPA:16684] synonym: "embryonic aortic arch artery" EXACT [EMAPA:16684, MP:0002672] synonym: "PAA" EXACT ABBREVIATION [MP:0002672] synonym: "pharyngeal arch arteries" RELATED PLURAL [] synonym: "pharyngeal arch artery" EXACT [MP:0002672] synonym: "pharyngeal arch artery" RELATED [VHOG:0000122] xref: AAO:0010414 xref: EFO:0003695 xref: EHDAA2:0000186 xref: EHDAA:398 xref: EHDAA:7327 xref: EMAPA:16684 xref: NCIT:C32123 xref: TAO:0005004 xref: UMLS:C0003489 {source="ncithesaurus:Aortic_Arch"} xref: VHOG:0000122 xref: Wikipedia:Aortic_arches xref: XAO:0000341 xref: ZFA:0005004 is_a: UBERON:0003469 ! respiratory system artery is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: contributes_to_morphology_of UBERON:0002539 ! pharyngeal arch relationship: has_potential_to_develop_into UBERON:0001637 ! artery relationship: part_of UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0007303 {source="ZFA"} ! pharyngeal vasculature property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/84/Gray473.png" xsd:anyURI property_value: editor_note "add specific artery derivatives" xsd:string property_value: IAO:0000232 "Do not confuse with arch of aorta." xsd:string property_value: UBPROP:0000001 "Paired vessels arching from the ventral to the dorsal aorta through the pharyngeal arches. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000122", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/aortic+arches"} property_value: UBPROP:0000003 "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000122", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Number varies - Lampreys have 8, hagfishes 15; only up to 6 appear in embryonic development in most gnathostome fishes and all tetrapods" xsd:string property_value: UBPROP:0000011 "The third, fourth, and sixth arches, along with the seventh intersegmental arteries and the left dorsal aorta, are the primary contributors to the normal aortic arch and its major thoracic branches" xsd:string [Term] id: UBERON:0004365 name: vitelline blood vessel namespace: uberon def: "Blood vessel that is connected to the yolk sac." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim xref: EMAPA:36494 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: connected_to UBERON:0001040 ! yolk sac relationship: connected_to UBERON:0001040 ! yolk sac relationship: part_of UBERON:0004374 ! vitelline vasculature [Term] id: UBERON:0004367 name: Descemet's membrane namespace: uberon def: "A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]." [https://github.com/obophenotype/uberon/issues/15, MP:0004285] comment: The strong, resistant, thin, noncellular fourth layer of the cornea, located between the endothelium (from which it is secreted) and the stroma. (Cline et al., Dictionary of Visual Science, 4th ed) subset: pheno_slim subset: vertebrate_core synonym: "Descemet membrane" EXACT [] synonym: "Descemet's posterior elastic lamina" EXACT [FMA:58309] synonym: "lamina limitans posterior" EXACT [FMA:58309] synonym: "lamina limitans posterior corneae" EXACT LATIN [FMA:58309, FMA:TA] synonym: "posterior limiting lamina" EXACT [MA:0001246] synonym: "posterior limiting lamina of cornea" EXACT [FMA:58309] synonym: "posterior limiting membrane" EXACT [ZFA:0001686] xref: EMAPA:18804 xref: FMA:58309 xref: GAID:894 xref: MA:0001246 xref: MESH:D003886 xref: NCIT:C32454 xref: SCTID:281076002 xref: TAO:0002157 xref: UMLS:C0011665 {source="ncithesaurus:Descemet_s_Membrane"} xref: Wikipedia:Descemet%27s_membrane xref: ZFA:0001686 is_a: UBERON:0005769 ! basement membrane of epithelium is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0005769 ! basement membrane of epithelium intersection_of: adjacent_to UBERON:0001777 ! substantia propria of cornea intersection_of: adjacent_to UBERON:0001985 ! corneal endothelium intersection_of: part_of UBERON:0000964 ! cornea disjoint_from: UBERON:0004370 {source="lexical"} ! anterior limiting lamina of cornea relationship: adjacent_to UBERON:0001777 ! substantia propria of cornea relationship: adjacent_to UBERON:0001985 ! corneal endothelium relationship: has_quality PATO:0000964 ! transparent relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/gkoutos relationship: part_of UBERON:0000964 ! cornea relationship: produced_by UBERON:0001985 {source="Cline et al"} ! corneal endothelium property_value: seeAlso "https://github.com/obophenotype/uberon/issues/15" xsd:anyURI property_value: UBPROP:0000001 "Acellular anatomical structure composed of collagen, Descemet's membrane is secreted as a basement membrane of the corneal endothelium. Located between the stroma and the corneal endothelium, it is approximately 0.15 micrometer thick at 6 months post-fertilization.[ZFIN]" xsd:string {date_retrieved="2016-05-01", external_class="TAO:0002157", ontology="ZFIN", source="ZFIN:ZDB-PUB-061010-3", source="https://orcid.org/0000-0001-9114-8737"} [Term] id: UBERON:0004370 name: anterior limiting lamina of cornea namespace: uberon def: "A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane." [ncithesaurus:Bowman_s_Membrane] subset: pheno_slim subset: vertebrate_core synonym: "anterior elastic lamina" EXACT [ZFA:0001684] synonym: "anterior limiting lamina" EXACT [MA:0001240] synonym: "anterior limiting lamina of cornea" EXACT [FMA:58273] synonym: "anterior limiting membrane" RELATED [ZFA:0001684] synonym: "Bowman's anterior elastic lamina" EXACT [FMA:58273] synonym: "Bowman's layer" EXACT [FMA:58273] synonym: "Bowman's membrane" EXACT [FMA:58273] synonym: "lamina limitans anterior (cornea)" EXACT [FMA:58273] synonym: "lamina limitans anterior corneae" EXACT LATIN [FMA:58273, FMA:TA] synonym: "Reichert's membrane" RELATED DUBIOUS [http://sourceforge.net/tracker/?func=detail&aid=2956371&group_id=76834&atid=974957] xref: FMA:58273 xref: MA:0001240 xref: NCIT:C32226 xref: SCTID:281075003 xref: TAO:0002155 xref: UMLS:C0229127 {source="ncithesaurus:Bowman_s_Membrane"} xref: Wikipedia:Bowman%27s_membrane xref: ZFA:0001684 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0005769 ! basement membrane of epithelium is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0005769 ! basement membrane of epithelium intersection_of: attaches_to UBERON:0001772 ! corneal epithelium intersection_of: part_of UBERON:0000964 ! cornea relationship: attaches_to UBERON:0001772 ! corneal epithelium relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000964 ! cornea property_value: UBPROP:0000001 "Acellular anatomical structure that is the zone of collagen fibers adjacent the basement membrane of the corneal epithelium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002155", ontology="TAO", source="ZFIN:ZDB-PUB-061010-3"} property_value: UBPROP:0000008 "Compared to terrestial animals, the cornea of zebrafish is relatively flat. It consists of nonpigmented, stratified squamous nonkeratinizing epithelial cells, attached to a thick basement membrane that is considered to be analogous to the Bowman's membrane in mammals" xsd:string [Term] id: UBERON:0004374 name: vitelline vasculature namespace: uberon def: "Vascular network that is connected to the yolk sac." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "omphalomesenteric system" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "vitelline bloos vessel system" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "vitelline system" RELATED [https://orcid.org/0000-0002-6601-2165] xref: Wikipedia:Vitelline_circulation is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: connected_to UBERON:0001040 ! yolk sac relationship: connected_to UBERON:0001040 ! yolk sac relationship: part_of RO:0002577 ! system [Term] id: UBERON:0004375 name: bone of free limb or fin namespace: uberon def: "A bone that is part of an appendage [Automatically generated definition]." [OBOL:automatic] subset: homology_grouping synonym: "appendage bone" EXACT [] synonym: "bone of appendage" EXACT [] synonym: "bone of free segment of appendicular skeleton" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010740 ! bone of appendage girdle complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0004708 ! paired limb/fin relationship: part_of UBERON:0011582 ! paired limb/fin skeleton [Term] id: UBERON:0004377 name: distal metaphysis namespace: uberon def: "A metaphysis that is in the distal side of a diaphysis." [OBOL:automatic] synonym: "distal diaphyseal end of long bone" EXACT [FMA:32824] xref: FMA:32824 is_a: UBERON:0001438 ! metaphysis intersection_of: UBERON:0001438 ! metaphysis intersection_of: in_distal_side_of UBERON:0004769 ! diaphysis relationship: in_distal_side_of UBERON:0004769 ! diaphysis [Term] id: UBERON:0004378 name: proximal metaphysis namespace: uberon def: "A metaphysis that is in the proximal side of a diaphysis." [OBOL:automatic] synonym: "proximal diaphyseal end of long bone" EXACT [FMA:32823] xref: FMA:32823 is_a: UBERON:0001438 ! metaphysis intersection_of: UBERON:0001438 ! metaphysis intersection_of: in_proximal_side_of UBERON:0004769 ! diaphysis relationship: in_proximal_side_of UBERON:0004769 ! diaphysis [Term] id: UBERON:0004379 name: distal epiphysis namespace: uberon def: "An epiphysis that is on the distal side of the bone." [http://orcid.org/0000-0002-6601-2165] synonym: "distal end of long bone" EXACT [FMA:32822] xref: FMA:32822 xref: SCTID:279999006 is_a: UBERON:0001437 ! epiphysis intersection_of: UBERON:0001437 ! epiphysis intersection_of: in_distal_side_of UBERON:0001474 ! bone element relationship: adjacent_to UBERON:0004377 ! distal metaphysis relationship: in_distal_side_of UBERON:0001474 ! bone element [Term] id: UBERON:0004380 name: proximal epiphysis namespace: uberon def: "An epiphysis that is on the proximal side of the bone." [http://orcid.org/0000-0002-6601-2165] synonym: "proximal end of long bone" EXACT [FMA:32821] xref: FMA:32821 xref: SCTID:279998003 is_a: UBERON:0001437 ! epiphysis intersection_of: UBERON:0001437 ! epiphysis intersection_of: in_proximal_side_of UBERON:0001474 ! bone element relationship: adjacent_to UBERON:0004378 ! proximal metaphysis relationship: in_proximal_side_of UBERON:0001474 ! bone element [Term] id: UBERON:0004381 name: skeleton of limb namespace: uberon def: "The collection of all skeletal elements in an individual limb." [https://orcid.org/0000-0002-6601-2165] synonym: "free limb skeleton" EXACT [VSAO:0000300] synonym: "limb skeleton" EXACT [EHDAA2:0002221] synonym: "set of bones of limb" EXACT [] xref: EHDAA2:0002221 xref: EMAPA:32702 xref: VSAO:0000300 is_a: UBERON:0010712 ! limb skeleton subdivision is_a: UBERON:0011582 ! paired limb/fin skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002101 ! limb relationship: skeleton_of UBERON:0002101 ! limb property_value: UBPROP:0000001 "Skeletal subdivision that is part of the limb.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000300", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"} property_value: UBPROP:0000012 "EHDAA2 considers hip and shoulder joints part of limb skeleton." xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0004382 name: epiphysis of humerus namespace: uberon def: "An epiphysis that is part of a humerus [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "humeral epiphysis" EXACT [OBOL:automatic] xref: FMA:32825 xref: SCTID:313054009 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0000976 ! humerus relationship: part_of UBERON:0000976 ! humerus [Term] id: UBERON:0004383 name: epiphysis of tibia namespace: uberon def: "An epiphysis that is part of a tibia [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "tibial epiphysis" EXACT [FMA:33112] xref: EMAPA:37771 {source="MA:th"} xref: FMA:33112 xref: MA:0003113 xref: SCTID:314626006 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0000979 ! tibia relationship: part_of UBERON:0000979 ! tibia [Term] id: UBERON:0004384 name: epiphysis of femur namespace: uberon def: "An epiphysis that is part of a femur [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "femoral epiphysis" EXACT [FMA:32838] xref: EMAPA:37539 {source="MA:th"} xref: FMA:32838 xref: MA:0003056 xref: SCTID:314625005 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0000981 ! femur relationship: part_of UBERON:0000981 ! femur [Term] id: UBERON:0004385 name: epiphysis of radius namespace: uberon def: "An epiphysis that is part of a radius [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "radial epiphysis" EXACT [FMA:33770] xref: FMA:33770 xref: SCTID:313055005 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001423 ! radius bone relationship: part_of UBERON:0001423 ! radius bone [Term] id: UBERON:0004386 name: epiphysis of ulna namespace: uberon def: "An epiphysis that is part of an ulna [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "ulnar epiphysis" EXACT [FMA:33748] xref: FMA:33748 xref: SCTID:313056006 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001424 ! ulna relationship: part_of UBERON:0001424 ! ulna [Term] id: UBERON:0004387 name: epiphysis of phalanx of manus namespace: uberon def: "An epiphysis that is part of a phalanx of a manus [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "epiphysis of phalanx of finger" EXACT [] synonym: "epiphysis of phalanx of hand" RELATED [FMA:240707] xref: FMA:240707 xref: SCTID:314620000 is_a: UBERON:0004446 ! epiphysis of phalanx intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001436 ! phalanx of manus relationship: part_of UBERON:0001436 ! phalanx of manus [Term] id: UBERON:0004388 name: epiphysis of fibula namespace: uberon def: "An epiphysis that is part of a fibula [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "fibula epiphysis" EXACT [FMA:33726] xref: FMA:33726 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001446 ! fibula relationship: part_of UBERON:0001446 ! fibula [Term] id: UBERON:0004389 name: epiphysis of metatarsal bone namespace: uberon def: "An epiphysis that is part of a metatarsal bone [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "epiphysis of metatarsal" EXACT [] synonym: "metatarsal bone epiphysis" EXACT [FMA:33814] synonym: "metatarsal epiphysis" EXACT [] xref: FMA:33814 xref: SCTID:313057002 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0011973 ! epiphysis of phalanx of pes intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0001448 ! metatarsal bone relationship: part_of UBERON:0001448 ! metatarsal bone [Term] id: UBERON:0004390 name: epiphysis of metacarpal bone namespace: uberon def: "An epiphysis that is part of a metacarpal bone [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "epiphysis of metacarpal" EXACT [] synonym: "metacarpal bone epiphysis" EXACT [FMA:33792] synonym: "metacarpal epiphysis" EXACT [] xref: FMA:33792 xref: SCTID:314907001 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0002374 ! metacarpal bone relationship: part_of UBERON:0002374 ! metacarpal bone [Term] id: UBERON:0004391 name: epiphysis of first metacarpal bone namespace: uberon def: "An epiphysis that is part of a metacarpal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "first metacarpal bone epiphysis" EXACT [FMA:33793] synonym: "metacarpal 1 epiphysis" EXACT [] xref: FMA:33793 is_a: UBERON:0004390 ! epiphysis of metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003645 ! metacarpal bone of digit 1 relationship: part_of UBERON:0003645 ! metacarpal bone of digit 1 [Term] id: UBERON:0004392 name: epiphysis of second metacarpal bone namespace: uberon def: "An epiphysis that is part of a metacarpal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "metacarpal 2 epiphysis" EXACT [] synonym: "second metacarpal bone epiphysis" EXACT [FMA:33794] xref: FMA:33794 is_a: UBERON:0004390 ! epiphysis of metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003646 ! metacarpal bone of digit 2 relationship: part_of UBERON:0003646 ! metacarpal bone of digit 2 [Term] id: UBERON:0004393 name: epiphysis of third metacarpal bone namespace: uberon def: "An epiphysis that is part of a metacarpal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "metacarpal 3 epiphysis" EXACT [] synonym: "third metacarpal bone epiphysis" EXACT [FMA:86328] xref: FMA:86328 is_a: UBERON:0004390 ! epiphysis of metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: part_of UBERON:0003647 ! metacarpal bone of digit 3 [Term] id: UBERON:0004394 name: epiphysis of fourth metacarpal bone namespace: uberon def: "An epiphysis that is part of a metacarpal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "fourth metacarpal bone epiphysis" EXACT [FMA:86329] synonym: "metacarpal 4 epiphysis" EXACT [] xref: FMA:86329 is_a: UBERON:0004390 ! epiphysis of metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003648 ! metacarpal bone of digit 4 relationship: part_of UBERON:0003648 ! metacarpal bone of digit 4 [Term] id: UBERON:0004395 name: epiphysis of first metatarsal bone namespace: uberon def: "An epiphysis that is part of a metatarsal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "first metatarsal bone epiphysis" EXACT [FMA:33815] synonym: "metatarsal 1 epiphysis" EXACT [] xref: FMA:33815 is_a: UBERON:0004389 ! epiphysis of metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003650 ! metatarsal bone of digit 1 relationship: part_of UBERON:0003650 ! metatarsal bone of digit 1 [Term] id: UBERON:0004396 name: epiphysis of second metatarsal bone namespace: uberon def: "An epiphysis that is part of a metatarsal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "metatarsal 2 epiphysis" EXACT [] synonym: "second metatarsal bone epiphysis" EXACT [FMA:33816] xref: FMA:33816 is_a: UBERON:0004389 ! epiphysis of metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003651 ! metatarsal bone of digit 2 relationship: part_of UBERON:0003651 ! metatarsal bone of digit 2 [Term] id: UBERON:0004397 name: epiphysis of third metatarsal bone namespace: uberon def: "An epiphysis that is part of a metatarsal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "metatarsal 3 epiphysis" EXACT [] synonym: "third metatarsal bone epiphysis" EXACT [FMA:86313] xref: FMA:86313 is_a: UBERON:0004389 ! epiphysis of metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: part_of UBERON:0003652 ! metatarsal bone of digit 3 [Term] id: UBERON:0004398 name: epiphysis of fourth metatarsal bone namespace: uberon def: "An epiphysis that is part of a metatarsal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "fourth metatarsal bone epiphysis" EXACT [FMA:86314] synonym: "metatarsal 4 epiphysis" EXACT [] xref: FMA:86314 is_a: UBERON:0004389 ! epiphysis of metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: part_of UBERON:0003653 ! metatarsal bone of digit 4 [Term] id: UBERON:0004399 name: epiphysis of fifth metatarsal bone namespace: uberon def: "An epiphysis that is part of a metatarsal bone of digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "fifth metatarsal bone epiphysis" EXACT [FMA:86315] synonym: "metatarsal 5 epiphysis" EXACT [] xref: FMA:86315 is_a: UBERON:0004389 ! epiphysis of metatarsal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003654 ! metatarsal bone of digit 5 relationship: part_of UBERON:0003654 ! metatarsal bone of digit 5 [Term] id: UBERON:0004400 name: bone tissue of epiphysis namespace: uberon def: "A portion of bone tissue that is part of a epiphysis [Automatically generated definition]." [OBOL:automatic] xref: FMA:241364 is_a: UBERON:0005808 ! bone tissue of long bone intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0001437 ! epiphysis relationship: part_of UBERON:0001437 ! epiphysis [Term] id: UBERON:0004401 name: bone tissue of distal epiphysis namespace: uberon def: "A portion of bone tissue that is part of a distal epiphysis [Automatically generated definition]." [OBOL:automatic] xref: FMA:241374 is_a: UBERON:0004400 ! bone tissue of epiphysis intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0004379 ! distal epiphysis relationship: part_of UBERON:0004379 ! distal epiphysis [Term] id: UBERON:0004402 name: bone tissue of proximal epiphysis namespace: uberon def: "A portion of bone tissue that is part of a proximal epiphysis [Automatically generated definition]." [OBOL:automatic] xref: FMA:241372 is_a: UBERON:0004400 ! bone tissue of epiphysis intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0004380 ! proximal epiphysis relationship: part_of UBERON:0004380 ! proximal epiphysis [Term] id: UBERON:0004404 name: distal epiphysis of humerus namespace: uberon def: "A distal epiphysis that is part of a humerus [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "distal end of humerus" EXACT [FMA:32826] synonym: "lower end of humerus" EXACT [FMA:32826] xref: FMA:32826 xref: SCTID:310655007 is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004382 ! epiphysis of humerus intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0000976 ! humerus [Term] id: UBERON:0004405 name: distal epiphysis of tibia namespace: uberon def: "A distal epiphysis that is part of a tibia [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "distal end of tibia" EXACT [FMA:33116] synonym: "lower end of tibia" EXACT [FMA:33116] xref: FMA:33116 xref: SCTID:302527001 xref: Wikipedia:Lower_extremity_of_tibia is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004383 ! epiphysis of tibia intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0000979 ! tibia [Term] id: UBERON:0004406 name: distal epiphysis of femur namespace: uberon def: "A distal epiphysis that is part of a femur [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "distal femoral epiphysis" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "distal head of femur" RELATED [AAO:0000893] xref: AAO:0000893 xref: FMA:32844 xref: SCTID:280016000 is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004384 ! epiphysis of femur intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0000981 ! femur property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Head of the femur that articulates with the tibia and fibula.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000893", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0004407 name: distal epiphysis of radius namespace: uberon def: "A distal epiphysis that is part of a radius [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "distal end of radius" EXACT [FMA:33776] synonym: "lower end of radius" EXACT [FMA:33776] xref: FMA:33776 xref: SCTID:280013008 xref: Wikipedia:Lower_extremity_of_radius is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004385 ! epiphysis of radius intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001423 ! radius bone [Term] id: UBERON:0004408 name: distal epiphysis of ulna namespace: uberon def: "A distal epiphysis that is part of a ulna [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "distal end of ulna" EXACT [FMA:33754] synonym: "lower end of ulna" EXACT [FMA:33754] xref: FMA:33754 xref: SCTID:302521000 is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004386 ! epiphysis of ulna intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001424 ! ulna [Term] id: UBERON:0004409 name: distal epiphysis of phalanx of manus namespace: uberon def: "A distal epiphysis that is part of a phalanx of manus [Automatically generated definition]." [OBOL:automatic] synonym: "distal end of phalanx of hand" RELATED [FMA:226577] synonym: "distal epiphysis of phalanx of finger" EXACT [] synonym: "distal epiphysis of phalanx of hand" RELATED [FMA:226577] synonym: "head of phalanx of finger" RELATED [FMA:226577] synonym: "head of phalanx of hand" RELATED [FMA:226577] synonym: "ungual tuberosity of distal phalanx of finger" RELATED [FMA:226577] xref: FMA:226577 xref: SCTID:272707006 is_a: UBERON:0004387 ! epiphysis of phalanx of manus is_a: UBERON:0004448 ! distal epiphysis of phalanx intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001436 ! phalanx of manus [Term] id: UBERON:0004410 name: distal epiphysis of fibula namespace: uberon def: "A distal epiphysis that is part of a fibula [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "distal end of fibula" EXACT [FMA:33732] synonym: "lower end of fibula" EXACT [FMA:33732] xref: FMA:33732 xref: SCTID:129111008 xref: SCTID:280018004 is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004388 ! epiphysis of fibula intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001446 ! fibula [Term] id: UBERON:0004411 name: proximal epiphysis of humerus namespace: uberon def: "The upper extremity of the humerus (proximal humerus) consists of a large rounded head joined to the body by a constricted portion called the neck, and two eminences, the greater and lesser tubercles." [Wikipedia:Upper_extremity_of_humerus] subset: pheno_slim synonym: "head of the humerus" RELATED [Wikipedia:Upper_extremity_of_humerus] synonym: "humeral head" RELATED [Wikipedia:Upper_extremity_of_humerus] synonym: "proximal end of humerus" EXACT [FMA:23362] synonym: "proximal humeral epiphysis" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "proximal humerus" RELATED [Wikipedia:Upper_extremity_of_humerus] synonym: "upper end of humerus" EXACT [FMA:23362] synonym: "upper extremity of humerus" RELATED [Wikipedia:Upper_extremity_of_humerus] xref: FMA:23362 xref: SCTID:280028008 xref: Wikipedia:Upper_extremity_of_humerus is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004382 ! epiphysis of humerus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0000976 ! humerus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/ad/Gray207.png" xsd:anyURI [Term] id: UBERON:0004412 name: proximal epiphysis of femur namespace: uberon def: "A proximal epiphysis that is part of a femur [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "capital femoral epiphysis" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "proximal femoral epiphysis" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] xref: FMA:32841 xref: SCTID:244702009 is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004384 ! epiphysis of femur intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0000981 ! femur [Term] id: UBERON:0004413 name: proximal epiphysis of radius namespace: uberon def: "A proximal epiphysis that is part of a radius [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "proximal end of radius" EXACT [FMA:39780] synonym: "proximal radial epiphysis" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] synonym: "upper end of radius" EXACT [FMA:39780] xref: FMA:39780 xref: SCTID:280029000 xref: Wikipedia:Upper_extremity_of_radius is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004385 ! epiphysis of radius intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001423 ! radius bone [Term] id: UBERON:0004414 name: proximal epiphysis of phalanx of manus namespace: uberon def: "A proximal epiphysis that is part of a phalanx of manus [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of finger" EXACT [FMA:226482] synonym: "base of phalanx of finger" EXACT [FMA:226482] synonym: "basis phalangis manus" EXACT LATIN [FMA:226482, FMA:TA] synonym: "proximal epiphysis of phalanx of finger" EXACT [] synonym: "proximal epiphysis of phalanx of hand" RELATED [FMA:226482] xref: FMA:226482 xref: SCTID:272704004 is_a: UBERON:0004387 ! epiphysis of phalanx of manus is_a: UBERON:0004447 ! proximal epiphysis of phalanx intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001436 ! phalanx of manus [Term] id: UBERON:0004415 name: proximal epiphysis of metatarsal bone namespace: uberon def: "A proximal epiphysis that is part of a metatarsal bone [Automatically generated definition]." [OBOL:automatic] synonym: "base of metatarsal bone" EXACT [FMA:33817] synonym: "basis ossis metatarsi" EXACT LATIN [FMA:33817, FMA:TA] synonym: "proximal end of metatarsal bone" EXACT [FMA:33817] synonym: "upper end of metatarsal bone" EXACT [FMA:33817] xref: FMA:33817 xref: SCTID:119545008 is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004389 ! epiphysis of metatarsal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001448 ! metatarsal bone [Term] id: UBERON:0004416 name: proximal epiphysis of metacarpal bone namespace: uberon def: "A proximal epiphysis that is part of a metacarpal bone [Automatically generated definition]." [OBOL:automatic] synonym: "base of metacarpal bone" EXACT [FMA:33795] synonym: "basis ossis metacarpi" EXACT LATIN [FMA:33795, FMA:TA] synonym: "metacarpal bone base" EXACT [FMA:33795] synonym: "proximal end of metacarpal bone" EXACT [FMA:33795] synonym: "upper end of metacarpal bone" EXACT [FMA:33795] xref: FMA:33795 xref: SCTID:272695001 is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004390 ! epiphysis of metacarpal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0002374 ! metacarpal bone [Term] id: UBERON:0004417 name: proximal epiphysis of phalanx of manual digit 1 namespace: uberon def: "A proximal epiphysis that is part of a manual digit 1 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of thumb" EXACT [FMA:37489] synonym: "base of phalanx of first digit of hand" EXACT [FMA:37489] synonym: "base of phalanx of thumb" EXACT [FMA:37489] synonym: "proximal epiphysis of phalanx of manual digit 1" EXACT [] synonym: "proximal epiphysis of phalanx of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of phalanx of thumb" NARROW SENSU [FMA:37489, NCBITaxon:9606] xref: FMA:37489 xref: SCTID:272700008 is_a: UBERON:0004414 ! proximal epiphysis of phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003620 ! manual digit 1 phalanx relationship: part_of UBERON:0003620 ! manual digit 1 phalanx [Term] id: UBERON:0004418 name: proximal epiphysis of phalanx of manual digit 2 namespace: uberon def: "A proximal epiphysis that is part of a manual digit 2 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of index finger" EXACT [FMA:37498] synonym: "base of phalanx of index finger" EXACT [FMA:37498] synonym: "base of phalanx of second digit of hand" EXACT [FMA:37498] synonym: "base of phalanx of second finger" EXACT [FMA:37498] synonym: "proximal epiphysis of phalanx of index finger" NARROW SENSU [FMA:37498, NCBITaxon:9606] synonym: "proximal epiphysis of phalanx of manual digit 2" EXACT [] synonym: "proximal epiphysis of phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37498 xref: SCTID:368307004 is_a: UBERON:0004414 ! proximal epiphysis of phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003636 ! manual digit 2 phalanx relationship: part_of UBERON:0003636 ! manual digit 2 phalanx [Term] id: UBERON:0004419 name: proximal epiphysis of phalanx of manual digit 3 namespace: uberon def: "A proximal epiphysis that is part of a manual digit 3 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of middle finger" EXACT [FMA:37510] synonym: "base of phalanx of middle finger" EXACT [FMA:37510] synonym: "base of phalanx of third digit of hand" EXACT [FMA:37510] synonym: "base of phalanx of third finger" EXACT [FMA:37510] synonym: "proximal epiphysis of phalanx of manual digit 3" EXACT [] synonym: "proximal epiphysis of phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of phalanx of middle finger" NARROW SENSU [FMA:37510, NCBITaxon:9606] xref: FMA:37510 xref: SCTID:181997000 is_a: UBERON:0004414 ! proximal epiphysis of phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003637 ! manual digit 3 phalanx relationship: part_of UBERON:0003637 ! manual digit 3 phalanx [Term] id: UBERON:0004420 name: proximal epiphysis of phalanx of manual digit 4 namespace: uberon def: "A proximal epiphysis that is part of a manual digit 4 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of ring finger" EXACT [FMA:37522] synonym: "base of phalanx of fourth digit of hand" EXACT [FMA:37522] synonym: "base of phalanx of fourth finger" EXACT [FMA:37522] synonym: "base of phalanx of ring finger" EXACT [FMA:37522] synonym: "proximal epiphysis of phalanx of manual digit 4" EXACT [] synonym: "proximal epiphysis of phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of phalanx of ring finger" NARROW SENSU [FMA:37522, NCBITaxon:9606] xref: FMA:37522 xref: SCTID:368337008 is_a: UBERON:0004414 ! proximal epiphysis of phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003638 ! manual digit 4 phalanx relationship: part_of UBERON:0003638 ! manual digit 4 phalanx [Term] id: UBERON:0004421 name: proximal epiphysis of phalanx of manual digit 5 namespace: uberon def: "A proximal epiphysis that is part of a manual digit 5 phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of phalanx of fifth finger" EXACT [FMA:37534] synonym: "basal epiphysis of phalanx of little finger" EXACT [FMA:37534] synonym: "base of phalanx of fifth digit of hand" EXACT [FMA:37534] synonym: "base of phalanx of fifth finger" EXACT [FMA:37534] synonym: "base of phalanx of little finger" EXACT [FMA:37534] synonym: "proximal epiphysis of phalanx of little finger" NARROW SENSU [FMA:37534, NCBITaxon:9606] synonym: "proximal epiphysis of phalanx of manual digit 5" EXACT [] synonym: "proximal epiphysis of phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37534 xref: SCTID:368351008 is_a: UBERON:0004414 ! proximal epiphysis of phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003639 ! manual digit 5 phalanx relationship: part_of UBERON:0003639 ! manual digit 5 phalanx [Term] id: UBERON:0004422 name: proximal epiphysis of first metacarpal bone namespace: uberon def: "A proximal epiphysis that is part of a metacarpal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "base of first metacarpal bone" EXACT [FMA:42788] synonym: "first metacarpal bone base" EXACT [FMA:42788] synonym: "proximal epiphysis of metacarpal 1" EXACT [] xref: FMA:42788 xref: SCTID:181978000 is_a: UBERON:0004391 ! epiphysis of first metacarpal bone is_a: UBERON:0004416 ! proximal epiphysis of metacarpal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003645 ! metacarpal bone of digit 1 [Term] id: UBERON:0004423 name: proximal epiphysis of second metacarpal bone namespace: uberon def: "A proximal epiphysis that is part of a metacarpal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "base of second metacarpal bone" EXACT [FMA:42791] synonym: "proximal end of second metacarpal bone" EXACT [FMA:42791] synonym: "proximal epiphysis of metacarpal 2" EXACT [] synonym: "second metacarpal bone base" EXACT [FMA:42791] xref: FMA:42791 xref: SCTID:263461004 is_a: UBERON:0004392 ! epiphysis of second metacarpal bone is_a: UBERON:0004416 ! proximal epiphysis of metacarpal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003646 ! metacarpal bone of digit 2 [Term] id: UBERON:0004424 name: proximal epiphysis of third metacarpal bone namespace: uberon def: "A proximal epiphysis that is part of a metacarpal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "base of third metacarpal bone" EXACT [FMA:42794] synonym: "proximal end of third metacarpal bone" EXACT [FMA:42794] synonym: "proximal epiphysis of metacarpal 3" EXACT [] synonym: "third metacarpal bone base" EXACT [FMA:42794] xref: FMA:42794 xref: SCTID:263465008 is_a: UBERON:0004393 ! epiphysis of third metacarpal bone is_a: UBERON:0004416 ! proximal epiphysis of metacarpal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003647 ! metacarpal bone of digit 3 [Term] id: UBERON:0004425 name: proximal epiphysis of fourth metacarpal bone namespace: uberon def: "A proximal epiphysis that is part of a metacarpal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fourth metacarpal bone" EXACT [FMA:42797] synonym: "fourth metacarpal bone base" EXACT [FMA:42797] synonym: "proximal end of fourth metacarpal bone" EXACT [FMA:42797] synonym: "proximal epiphysis of metacarpal 4" EXACT [] xref: FMA:42797 xref: SCTID:263469002 is_a: UBERON:0004394 ! epiphysis of fourth metacarpal bone is_a: UBERON:0004416 ! proximal epiphysis of metacarpal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003648 ! metacarpal bone of digit 4 [Term] id: UBERON:0004426 name: proximal epiphysis of fifth metacarpal bone namespace: uberon def: "A proximal epiphysis that is part of a metacarpal bone of digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fifth metacarpal bone" EXACT [FMA:42800] synonym: "fifth metacarpal bone base" EXACT [FMA:42800] synonym: "proximal end of fifth metacarpal bone" EXACT [FMA:42800] synonym: "proximal epiphysis of metacarpal 5" EXACT [] xref: FMA:42800 xref: SCTID:263473004 is_a: UBERON:0004416 ! proximal epiphysis of metacarpal bone is_a: UBERON:0011104 ! epiphysis of fifth metacarpal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003649 ! metacarpal bone of digit 5 [Term] id: UBERON:0004427 name: proximal epiphysis of first metatarsal bone namespace: uberon def: "A proximal epiphysis that is part of a metatarsal bone of digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "base of first metatarsal bone" EXACT [FMA:42963] synonym: "proximal end of first metatarsal bone" EXACT [FMA:42963] synonym: "proximal epiphysis of metatarsal 1" EXACT [] xref: FMA:42963 xref: SCTID:182124002 is_a: UBERON:0004395 ! epiphysis of first metatarsal bone is_a: UBERON:0004415 ! proximal epiphysis of metatarsal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003650 ! metatarsal bone of digit 1 [Term] id: UBERON:0004428 name: proximal epiphysis of second metatarsal bone namespace: uberon def: "A proximal epiphysis that is part of a metatarsal bone of digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "base of second metatarsal bone" EXACT [FMA:42964] synonym: "proximal end of second metatarsal bone" EXACT [FMA:42964] synonym: "proximal epiphysis of metatarsal 2" EXACT [] xref: FMA:42964 xref: SCTID:182130002 is_a: UBERON:0004396 ! epiphysis of second metatarsal bone is_a: UBERON:0004415 ! proximal epiphysis of metatarsal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003651 ! metatarsal bone of digit 2 [Term] id: UBERON:0004429 name: proximal epiphysis of third metatarsal bone namespace: uberon def: "A proximal epiphysis that is part of a metatarsal bone of digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "base of third metatarsal bone" EXACT [FMA:42965] synonym: "proximal end of third metatarsal bone" EXACT [FMA:42965] synonym: "proximal epiphysis of metatarsal 3" EXACT [] xref: FMA:42965 xref: SCTID:182135007 is_a: UBERON:0004397 ! epiphysis of third metatarsal bone is_a: UBERON:0004415 ! proximal epiphysis of metatarsal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003652 ! metatarsal bone of digit 3 [Term] id: UBERON:0004430 name: proximal epiphysis of fourth metatarsal bone namespace: uberon def: "A proximal epiphysis that is part of a metatarsal bone of digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fourth metatarsal bone" EXACT [FMA:42966] synonym: "proximal end of fourth metatarsal bone" EXACT [FMA:42966] synonym: "proximal epiphysis of metatarsal 4" EXACT [] xref: FMA:42966 xref: SCTID:182140004 is_a: UBERON:0004398 ! epiphysis of fourth metatarsal bone is_a: UBERON:0004415 ! proximal epiphysis of metatarsal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003653 ! metatarsal bone of digit 4 [Term] id: UBERON:0004431 name: proximal epiphysis of fifth metatarsal bone namespace: uberon def: "A proximal epiphysis that is part of a metatarsal bone of digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "base of fifth metatarsal bone" EXACT [FMA:42967] synonym: "proximal end of fifth metatarsal bone" EXACT [FMA:42967] synonym: "proximal epiphysis of metatarsal 5" EXACT [] xref: FMA:42967 xref: SCTID:182145009 is_a: UBERON:0004399 ! epiphysis of fifth metatarsal bone is_a: UBERON:0004415 ! proximal epiphysis of metatarsal bone intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003654 ! metatarsal bone of digit 5 [Term] id: UBERON:0004432 name: proximal epiphysis of distal phalanx of manual digit 2 namespace: uberon def: "A proximal epiphysis that is part of a distal phalanx of manual digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of distal phalanx of index finger" EXACT [FMA:37505] synonym: "base of distal phalanx of index finger" EXACT [FMA:37505] synonym: "base of distal phalanx of second digit of hand" EXACT [FMA:37505] synonym: "base of distal phalanx of second finger" EXACT [FMA:37505] synonym: "proximal epiphysis of distal phalanx of index finger" NARROW SENSU [FMA:37505, NCBITaxon:9606] synonym: "proximal epiphysis of distal phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37505 xref: SCTID:263445001 is_a: UBERON:0004418 ! proximal epiphysis of phalanx of manual digit 2 is_a: UBERON:0011979 ! epiphysis of distal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004311 ! distal phalanx of manual digit 2 relationship: part_of UBERON:0004311 ! distal phalanx of manual digit 2 [Term] id: UBERON:0004433 name: proximal epiphysis of distal phalanx of manual digit 3 namespace: uberon def: "A proximal epiphysis that is part of a distal phalanx of manual digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "base of distal phalanx of middle finger" EXACT [FMA:37517] synonym: "base of distal phalanx of third digit of hand" EXACT [FMA:37517] synonym: "base of distal phalanx of third finger" EXACT [FMA:37517] synonym: "proximal epiphysis of distal phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of distal phalanx of middle finger" NARROW SENSU [FMA:37517, NCBITaxon:9606] xref: FMA:37517 xref: SCTID:263446000 is_a: UBERON:0004419 ! proximal epiphysis of phalanx of manual digit 3 is_a: UBERON:0011979 ! epiphysis of distal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004312 ! distal phalanx of manual digit 3 relationship: part_of UBERON:0004312 ! distal phalanx of manual digit 3 [Term] id: UBERON:0004434 name: proximal epiphysis of distal phalanx of manual digit 4 namespace: uberon def: "A proximal epiphysis that is part of a distal phalanx of manual digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of distal phalanx of fourth finger" EXACT [FMA:37529] synonym: "basal epiphysis of distal phalanx of ring finger" EXACT [FMA:37529] synonym: "base of distal phalanx of fourth digit of hand" EXACT [FMA:37529] synonym: "base of distal phalanx of fourth finger" EXACT [FMA:37529] synonym: "base of distal phalanx of ring finger" EXACT [FMA:37529] synonym: "proximal epiphysis of distal phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of distal phalanx of ring finger" NARROW SENSU [FMA:37529, NCBITaxon:9606] xref: FMA:37529 xref: SCTID:263447009 is_a: UBERON:0004420 ! proximal epiphysis of phalanx of manual digit 4 is_a: UBERON:0011979 ! epiphysis of distal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004313 ! distal phalanx of manual digit 4 relationship: part_of UBERON:0004313 ! distal phalanx of manual digit 4 [Term] id: UBERON:0004435 name: proximal epiphysis of distal phalanx of manual digit 5 namespace: uberon def: "A proximal epiphysis that is part of a distal phalanx of manual digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of distal phalanx of fifth finger" EXACT [FMA:37541] synonym: "basal epiphysis of distal phalanx of little finger" EXACT [FMA:37541] synonym: "base of distal phalanx of fifth digit of hand" EXACT [FMA:37541] synonym: "base of distal phalanx of fifth finger" EXACT [FMA:37541] synonym: "base of distal phalanx of little finger" EXACT [FMA:37541] synonym: "proximal epiphysis of distal phalanx of little finger" NARROW SENSU [FMA:37541, NCBITaxon:9606] synonym: "proximal epiphysis of distal phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37541 xref: SCTID:263448004 is_a: UBERON:0004421 ! proximal epiphysis of phalanx of manual digit 5 is_a: UBERON:0011979 ! epiphysis of distal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004314 ! distal phalanx of manual digit 5 relationship: part_of UBERON:0004314 ! distal phalanx of manual digit 5 [Term] id: UBERON:0004436 name: proximal epiphysis of middle phalanx of manual digit 2 namespace: uberon def: "A proximal epiphysis that is part of a middle phalanx of manual digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of index finger" EXACT [FMA:37502] synonym: "base of middle phalanx of index finger" EXACT [FMA:37502] synonym: "base of middle phalanx of second digit of hand" EXACT [FMA:37502] synonym: "base of middle phalanx of second finger" EXACT [FMA:37502] synonym: "proximal epiphysis of middle phalanx of index finger" NARROW SENSU [FMA:37502, NCBITaxon:9606] synonym: "proximal epiphysis of middle phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37502 xref: SCTID:263428006 is_a: UBERON:0004418 ! proximal epiphysis of phalanx of manual digit 2 is_a: UBERON:0011978 ! epiphysis of middle phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004320 ! middle phalanx of manual digit 2 relationship: part_of UBERON:0004320 ! middle phalanx of manual digit 2 [Term] id: UBERON:0004437 name: proximal epiphysis of middle phalanx of manual digit 3 namespace: uberon def: "A proximal epiphysis that is part of a middle phalanx of manual digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of middle finger" EXACT [FMA:37514] synonym: "base of middle phalanx of middle finger" EXACT [FMA:37514] synonym: "base of middle phalanx of third digit of hand" EXACT [FMA:37514] synonym: "base of middle phalanx of third finger" EXACT [FMA:37514] synonym: "proximal epiphysis of middle phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of middle phalanx of middle finger" NARROW SENSU [FMA:37514, NCBITaxon:9606] xref: FMA:37514 xref: SCTID:263429003 is_a: UBERON:0004419 ! proximal epiphysis of phalanx of manual digit 3 is_a: UBERON:0011978 ! epiphysis of middle phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004321 ! middle phalanx of manual digit 3 relationship: part_of UBERON:0004321 ! middle phalanx of manual digit 3 [Term] id: UBERON:0004438 name: proximal epiphysis of middle phalanx of manual digit 4 namespace: uberon def: "A proximal epiphysis that is part of a middle phalanx of manual digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of fourth finger" EXACT [FMA:37526] synonym: "basal epiphysis of middle phalanx of ring finger" EXACT [FMA:37526] synonym: "base of middle phalanx of fourth digit of hand" EXACT [FMA:37526] synonym: "base of middle phalanx of fourth finger" EXACT [FMA:37526] synonym: "base of middle phalanx of ring finger" EXACT [FMA:37526] synonym: "proximal epiphysis of middle phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of middle phalanx of ring finger" NARROW SENSU [FMA:37526, NCBITaxon:9606] xref: FMA:37526 xref: SCTID:263430008 is_a: UBERON:0004420 ! proximal epiphysis of phalanx of manual digit 4 is_a: UBERON:0011978 ! epiphysis of middle phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004322 ! middle phalanx of manual digit 4 relationship: part_of UBERON:0004322 ! middle phalanx of manual digit 4 [Term] id: UBERON:0004439 name: proximal epiphysis of middle phalanx of manual digit 5 namespace: uberon def: "A proximal epiphysis that is part of a middle phalanx of manual digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of middle phalanx of fifth finger" EXACT [FMA:37538] synonym: "basal epiphysis of middle phalanx of little finger" EXACT [FMA:37538] synonym: "base of middle phalanx of fifth digit of hand" EXACT [FMA:37538] synonym: "base of middle phalanx of fifth finger" EXACT [FMA:37538] synonym: "base of middle phalanx of little finger" EXACT [FMA:37538] synonym: "proximal epiphysis of middle phalanx of little finger" NARROW SENSU [FMA:37538, NCBITaxon:9606] synonym: "proximal epiphysis of middle phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37538 xref: SCTID:263431007 is_a: UBERON:0004421 ! proximal epiphysis of phalanx of manual digit 5 is_a: UBERON:0011978 ! epiphysis of middle phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004323 ! middle phalanx of manual digit 5 relationship: part_of UBERON:0004323 ! middle phalanx of manual digit 5 [Term] id: UBERON:0004440 name: proximal epiphysis of proximal phalanx of manual digit 2 namespace: uberon def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 2 [Automatically generated definition]." [OBOL:automatic] synonym: "base of proximal phalanx of index finger" EXACT [FMA:37499] synonym: "base of proximal phalanx of second digit of hand" EXACT [FMA:37499] synonym: "base of proximal phalanx of second finger" EXACT [FMA:37499] synonym: "proximal epiphysis of proximal phalanx of index finger" NARROW SENSU [FMA:37499, NCBITaxon:9606] synonym: "proximal epiphysis of proximal phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37499 xref: SCTID:263412001 is_a: UBERON:0004418 ! proximal epiphysis of phalanx of manual digit 2 is_a: UBERON:0011977 ! epiphysis of proximal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004328 ! proximal phalanx of manual digit 2 relationship: part_of UBERON:0004328 ! proximal phalanx of manual digit 2 [Term] id: UBERON:0004441 name: proximal epiphysis of proximal phalanx of manual digit 3 namespace: uberon def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 3 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of middle finger" EXACT [FMA:37511] synonym: "base of proximal phalanx of middle finger" EXACT [FMA:37511] synonym: "base of proximal phalanx of third digit of hand" EXACT [FMA:37511] synonym: "base of proximal phalanx of third finger" EXACT [FMA:37511] synonym: "proximal epiphysis of proximal phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of proximal phalanx of middle finger" NARROW SENSU [FMA:37511, NCBITaxon:9606] xref: FMA:37511 xref: SCTID:263413006 is_a: UBERON:0004419 ! proximal epiphysis of phalanx of manual digit 3 is_a: UBERON:0011977 ! epiphysis of proximal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004329 ! proximal phalanx of manual digit 3 relationship: part_of UBERON:0004329 ! proximal phalanx of manual digit 3 [Term] id: UBERON:0004442 name: proximal epiphysis of proximal phalanx of manual digit 4 namespace: uberon def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 4 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of fourth finger" EXACT [FMA:37523] synonym: "basal epiphysis of proximal phalanx of ring finger" EXACT [FMA:37523] synonym: "base of proximal phalanx of fourth digit of hand" EXACT [FMA:37523] synonym: "base of proximal phalanx of fourth finger" EXACT [FMA:37523] synonym: "base of proximal phalanx of ring finger" EXACT [FMA:37523] synonym: "proximal epiphysis of proximal phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of proximal phalanx of ring finger" NARROW SENSU [FMA:37523, NCBITaxon:9606] xref: FMA:37523 xref: SCTID:263414000 is_a: UBERON:0004420 ! proximal epiphysis of phalanx of manual digit 4 is_a: UBERON:0011977 ! epiphysis of proximal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004330 ! proximal phalanx of manual digit 4 relationship: part_of UBERON:0004330 ! proximal phalanx of manual digit 4 [Term] id: UBERON:0004443 name: proximal epiphysis of proximal phalanx of manual digit 5 namespace: uberon def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 5 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of little finger" EXACT [FMA:37535] synonym: "base of proximal phalanx of fifth digit of hand" EXACT [FMA:37535] synonym: "base of proximal phalanx of fifth finger" EXACT [FMA:37535] synonym: "base of proximal phalanx of little finger" EXACT [FMA:37535] synonym: "proximal epiphysis of proximal phalanx of little finger" NARROW SENSU [FMA:37535, NCBITaxon:9606] synonym: "proximal epiphysis of proximal phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:37535 xref: SCTID:263415004 is_a: UBERON:0004421 ! proximal epiphysis of phalanx of manual digit 5 is_a: UBERON:0011977 ! epiphysis of proximal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004331 ! proximal phalanx of manual digit 5 relationship: part_of UBERON:0004331 ! proximal phalanx of manual digit 5 [Term] id: UBERON:0004444 name: proximal epiphysis of distal phalanx of manual digit 1 namespace: uberon def: "A proximal epiphysis that is part of a distal phalanx of manual digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "base of distal phalanx of thumb" EXACT [FMA:37493] synonym: "proximal epiphysis of distal phalanx of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of distal phalanx of thumb" NARROW SENSU [FMA:37493, NCBITaxon:9606] xref: FMA:37493 xref: SCTID:182008001 is_a: UBERON:0004417 ! proximal epiphysis of phalanx of manual digit 1 is_a: UBERON:0011979 ! epiphysis of distal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004337 ! distal phalanx of manual digit 1 relationship: part_of UBERON:0004337 ! distal phalanx of manual digit 1 [Term] id: UBERON:0004445 name: proximal epiphysis of proximal phalanx of manual digit 1 namespace: uberon def: "A proximal epiphysis that is part of a proximal phalanx of manual digit 1 [Automatically generated definition]." [OBOL:automatic] synonym: "basal epiphysis of proximal phalanx of thumb" EXACT [FMA:37490] synonym: "base of proximal phalanx of thumb" EXACT [FMA:37490] synonym: "proximal epiphysis of proximal phalanx of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal epiphysis of proximal phalanx of thumb" NARROW SENSU [FMA:37490, NCBITaxon:9606] xref: FMA:37490 xref: SCTID:181993001 is_a: UBERON:0004417 ! proximal epiphysis of phalanx of manual digit 1 is_a: UBERON:0011977 ! epiphysis of proximal phalanx of manus intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0004338 ! proximal phalanx of manual digit 1 relationship: part_of UBERON:0004338 ! proximal phalanx of manual digit 1 [Term] id: UBERON:0004446 name: epiphysis of phalanx namespace: uberon def: "An epiphysis that is part of a phalanx [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim xref: SCTID:280033007 is_a: UBERON:0001437 ! epiphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003221 ! phalanx relationship: part_of UBERON:0003221 ! phalanx [Term] id: UBERON:0004447 name: proximal epiphysis of phalanx namespace: uberon def: "A proximal epiphysis that is part of a phalanx [Automatically generated definition]." [OBOL:automatic] is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004446 ! epiphysis of phalanx intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0003221 ! phalanx [Term] id: UBERON:0004448 name: distal epiphysis of phalanx namespace: uberon def: "A distal epiphysis that is part of a phalanx [Automatically generated definition]." [OBOL:automatic] synonym: "head of phalanx" EXACT [] xref: SCTID:110520001 is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004446 ! epiphysis of phalanx intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0003221 ! phalanx [Term] id: UBERON:0004449 name: cerebral artery namespace: uberon def: "One of three main pairs of arteries and their branches, which irrigate the cerebrum of the brain." [Wikipedia:Cerebral_artery] subset: pheno_slim xref: AAO:0010493 xref: BTO:0005205 xref: CALOHA:TS-0126 xref: EHDAA2:0000233 xref: EHDAA:5294 xref: EMAPA:18613 xref: GAID:484 xref: MA:0002562 xref: MESH:D002536 xref: NCIT:C12691 xref: SCTID:181308008 xref: UMLS:C0007770 {source="ncithesaurus:Cerebral_Artery"} xref: Wikipedia:Cerebral_artery xref: XAO:0000367 is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001893 ! telencephalon relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0003709 ! circle of Willis relationship: supplies UBERON:0001893 ! telencephalon property_value: UBPROP:0000001 "Part of the internal carotid containing many branches supplying blood to the chorioid plexuses of the brain.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010493", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000002 "relationship loss: part_of internal carotid (AAO:0010219)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010493", ontology="AAO"} property_value: UBPROP:0000012 "in AAO this is part_of the internal carotid, but in humans the PCA intervenes for some cerebral arteries. Proper comparative review required" xsd:string {external_ontology="AAO"} [Term] id: UBERON:0004451 name: trunk or cervical vertebra namespace: uberon def: "A vertebra in the trunk or cervical region. Includes all cervical, thoracic and lumbar vertebrae, but excludes caudal vertebra." [UBERONREF:0000006] subset: pheno_slim synonym: "presacral vertebra" RELATED [MA:0002869] xref: EMAPA:37722 {source="MA:th"} xref: MA:0002869 xref: XAO:0003077 is_a: UBERON:0002412 ! vertebra intersection_of: UBERON:0002412 ! vertebra intersection_of: anterior_to UBERON:0001095 ! caudal vertebra union_of: UBERON:0002413 ! cervical vertebra union_of: UBERON:0011677 ! trunk vertebra relationship: anterior_to UBERON:0001095 ! caudal vertebra property_value: UBPROP:0000008 "In humans, there are 24 presacral vertebrae (7 cervical, 12 thoracic, and 5 lumbar)" xsd:string property_value: UBPROP:0000012 "it's not clear if the XAO class belongs here or below" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0004452 name: carpal region namespace: uberon alt_id: UBERON:0001462 def: "A mesopodium that is part of a manus. Includes as parts the carpal skeleton and associated tissues[cjm]. The anatomical region surrounding the carpus including the distal parts of the bones of the forearm and the proximal parts of the metacarpus or five metacarpal bones and the series of joints between these bones, thus referred to as wrist joints. This region also includes the carpal tunnel, the anatomical snuff box, the flexor retinaculum, and the extensor retinaculum[WP,unvetted]." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Wrist] subset: pheno_slim subset: uberon_slim synonym: "articulatio radiocarpea" RELATED LATIN [Wikipedia:Wrist] synonym: "carpal limb segment" EXACT [] synonym: "carpal segment" EXACT [] synonym: "carpus" RELATED INCONSISTENT [] synonym: "carpus of fore-paw" NARROW [EMAPA:19122] synonym: "fore basipodium" EXACT [MA:th] synonym: "fore mesopodium" EXACT [MA:th] synonym: "hand mesopodium" EXACT [] synonym: "manus mesopodium" EXACT [] synonym: "regio carpalis" EXACT LATIN [FMA:24922, FMA:TA] synonym: "wrist" EXACT [MA:0000039] synonym: "wrist region" EXACT [] xref: EHDAA2:0000218 xref: EHDAA:5196 xref: EMAPA:19122 xref: EMAPA:32784 xref: FMA:24922 xref: GAID:59 xref: galen:Wrist xref: MA:0000039 xref: MESH:D014953 xref: NCIT:C111033 xref: SCTID:361289009 xref: Wikipedia:Wrist is_a: UBERON:0006716 ! mesopodium region is_a: UBERON:0008785 {source="FMA"} ! upper limb segment intersection_of: UBERON:0006716 ! mesopodium region intersection_of: part_of UBERON:0002398 ! manus relationship: distally_connected_to UBERON:0004453 ! metacarpus region relationship: has_skeleton UBERON:0009880 ! carpal skeleton relationship: part_of UBERON:0002398 ! manus relationship: proximally_connected_to UBERON:0002386 ! forelimb zeugopod property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/4a/Human_wrist.png" xsd:anyURI property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/c/cc/Hand_parts.jpg" xsd:anyURI [Term] id: UBERON:0004453 name: metacarpus region namespace: uberon def: "A metapodium region that is part of a manus." [OBOL:automatic] subset: pheno_slim synonym: "distal segment of hand proper" EXACT [FMA:24925] synonym: "forelimb cannon region" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "forelimb equine cannon region" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "metacarpal part of hand" EXACT [FMA:24925] synonym: "metacarpal part of manus" EXACT [] synonym: "metacarpal region" EXACT [FMA:24925] synonym: "metacarpus" EXACT [MA:0000042] xref: CALOHA:TS-2218 xref: EMAPA:32654 xref: FMA:24925 xref: MA:0000042 xref: SCTID:370638006 is_a: UBERON:0005451 {source="FMA"} ! segment of manus is_a: UBERON:0009877 ! metapodium region intersection_of: UBERON:0009877 ! metapodium region intersection_of: part_of UBERON:0002398 ! manus relationship: has_skeleton UBERON:0010544 ! metacarpus skeleton relationship: part_of UBERON:0012141 {source="PHENOSCAPE:ni"} ! manual digitopodium region property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/2/2f/Metacarpals_numbered-en.svg" xsd:anyURI property_value: editor_note "Note that along with FMA we treat this as a limb segment rather than a purely skeletal element" xsd:string property_value: UBPROP:0000007 "metacarpal" xsd:string property_value: UBPROP:0000012 "Note that mammalian and non-mammalian AOs differ in whether they consider this a part of the skeleton" xsd:string [Term] id: UBERON:0004454 name: tarsal region namespace: uberon alt_id: UBERON:0002388 def: "Mesopodial segment of the pes, including the tarsal skeleton and associated tissues." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Ankle] subset: efo_slim subset: pheno_slim subset: uberon_slim synonym: "ankle" EXACT [MA:0000043] synonym: "ankle region" EXACT [] synonym: "articulatio talocruralis" RELATED LATIN [Wikipedia:Ankle] synonym: "hind basipodium" RELATED [MA:th] synonym: "hind mesopodium" RELATED [MA:th] synonym: "hock" RELATED SENSU [Wikipedia:Hock_(anatomy)] synonym: "tarsal limb segment" EXACT [] xref: CALOHA:TS-2219 xref: EFO:0001409 xref: EMAPA:32783 xref: FMA:9665 xref: GAID:41 xref: galen:Ankle xref: MA:0000043 xref: MESH:D000842 xref: SCTID:361292008 xref: Wikipedia:Ankle is_a: UBERON:0006716 ! mesopodium region is_a: UBERON:0008784 ! lower limb segment intersection_of: UBERON:0006716 ! mesopodium region intersection_of: part_of UBERON:0002387 ! pes relationship: distally_connected_to UBERON:0000983 ! metatarsus region relationship: has_skeleton UBERON:0009879 ! tarsal skeleton relationship: part_of UBERON:0002387 ! pes relationship: proximally_connected_to UBERON:0003823 ! hindlimb zeugopod property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/b/bf/Ankle_en.svg" xsd:anyURI property_value: IAO:0000232 "this term refers to the limb segment. See also: tarsal bones and tarsal skeleton" xsd:string property_value: UBPROP:0000012 "MA has both tarsus (part of foot, has tarsal bone) and ankle (part of hindlimb, has joint, nerve, skin)." xsd:string {external_ontology="MA"} [Term] id: UBERON:0004455 name: neurula embryo namespace: uberon alt_id: UBERON:0007013 def: "An embryo at the neurula stage." [http://orcid.org/0000-0002-6601-2165] synonym: "neurula" EXACT [BTO:0001766] xref: BILA:0000061 xref: BTO:0001766 xref: NCIT:C34229 xref: UMLS:C1518306 {source="ncithesaurus:Neurula"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_and_ends_during UBERON:0000110 ! neurula stage relationship: develops_from UBERON:0004734 ! gastrula relationship: existence_starts_and_ends_during UBERON:0000110 ! neurula stage [Term] id: UBERON:0004456 name: entire sense organ system namespace: uberon def: "Sum of all sensory systems in an organism." [http://orcid.org/0000-0002-6601-2165] subset: uberon_slim synonym: "sense organ system" EXACT [FMA:78499] xref: FMA:78499 is_a: UBERON:0000467 ! anatomical system disjoint_from: UBERON:8450002 ! excretory system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: overlaps UBERON:0001016 ! nervous system property_value: UBPROP:0000012 "note the distinct between entire sensory system and individual system. this reconciles is_a and part_of distinctions between ssAOs" xsd:string [Term] id: UBERON:0004461 name: skeletal musculature of head namespace: uberon def: "Any collection of skeletal muscles that is part of a head [Automatically generated definition]." [OBOL:automatic] comment: This class is restricted to skeletal muscles that attach to the cranial skeleton. This seems to be consistent with FMA and EMAPA usage. Note that by definition this excludes invertebrate head musculature. It corresponds to the individual muscle organ term UBERON:0002376 subset: non_informative synonym: "head musculature" EXACT [FMA:71287] synonym: "muscle group of head" EXACT [FMA:71287] synonym: "muscles of head" EXACT [FMA:71287] synonym: "musculi capitis" EXACT LATIN [FMA:71287, FMA:TA] synonym: "set of muscles of head" EXACT [FMA:71287] xref: EMAPA:18171 xref: FMA:71287 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0008229 ! craniocervical region musculature intersection_of: UBERON:0001015 ! musculature intersection_of: attaches_to UBERON:0003129 ! skull intersection_of: part_of UBERON:0000033 ! head relationship: attaches_to UBERON:0003129 ! skull relationship: develops_from UBERON:0005253 ! head mesenchyme relationship: part_of UBERON:0000033 ! head relationship: part_of UBERON:0013700 ! axial musculature property_value: seeAlso "https://github.com/obophenotype/mouse-anatomy-ontology/issues/4" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/1405" xsd:anyURI [Term] id: UBERON:0004462 name: musculature of body wall namespace: uberon def: "Any collection of muscles that is part of a body wall [Automatically generated definition]." [OBOL:automatic] synonym: "body wall muscles" RELATED [] synonym: "body wall musculature" EXACT [FMA:86931] xref: BSA:0000058 xref: BTO:0001863 xref: EMAPA:37853 {source="MA:th"} xref: FMA:86931 xref: WBbt:0005813 is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000309 ! body wall relationship: part_of UBERON:0000309 ! body wall property_value: UBPROP:0000008 "define generically to encompass both vertebrates and invertebrates" xsd:string [Term] id: UBERON:0004463 name: musculature of hindlimb stylopod namespace: uberon def: "Any collection of muscles that is part of a hindlimb stylopod (upper leg / thigh)[Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "muscle group of thigh" EXACT [FMA:50208] synonym: "musculature of thigh" EXACT [FMA:50208] synonym: "set of muscles of thigh" EXACT [FMA:50208] synonym: "thigh musculature" EXACT [FMA:50208] xref: FMA:50208 is_a: UBERON:0004466 ! musculature of leg intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0004464 name: musculature of thorax namespace: uberon def: "Any collection of muscles that is part of a thorax [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "muscle group of thorax" EXACT [FMA:71293] synonym: "muscles of thorax" EXACT [FMA:71293] synonym: "musculi thoracis" EXACT LATIN [FMA:71293, FMA:TA] synonym: "set of muscles of thorax" EXACT [FMA:71293] synonym: "thoracic musculature" EXACT [FMA:71293] xref: BTO:0000508 xref: EMAPA:37260 {source="MA:th"} xref: FMA:71293 is_a: UBERON:0004479 ! musculature of trunk intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk property_value: UBPROP:0000012 "BTO and FMA do not mean precisely the same thing here. BTO thorax muscle is a pectoral muscle or diaphragm" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0004465 name: musculature of neck namespace: uberon def: "Any collection of muscles that is part of a neck [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "cervical muscles" EXACT [AAO:0000091] synonym: "muscle group of neck" EXACT [FMA:71290] synonym: "muscles of neck" EXACT [FMA:71290] synonym: "musculi cervicis" EXACT LATIN [FMA:71290, FMA:TA] synonym: "musculi colli" EXACT LATIN [FMA:71290, FMA:TA] synonym: "neck musculature" EXACT [FMA:71290] synonym: "set of muscles of neck" EXACT [FMA:71290] xref: AAO:0000091 xref: EMAPA:36050 xref: FMA:71290 xref: MESH:D009334 is_a: UBERON:0008229 ! craniocervical region musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000974 ! neck relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0004466 name: musculature of leg namespace: uberon alt_id: UBERON:0005632 def: "Any collection of muscles that is part of a lower leg or upper leg [Automatically generated definition]." [OBOL:automatic] synonym: "leg muscle system" EXACT [EHDAA2:0000973] xref: EHDAA2:0000973 is_a: UBERON:0004482 ! musculature of lower limb intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0000978 ! leg property_value: UBPROP:0000013 "see notes on UBERON:0000978 for possible confusion over the term 'leg'. This class represents the class-union of upper leg musculature and lower leg musculature (and thus may not mean precisely the same thing as the EHDAA2 class)" xsd:string [Term] id: UBERON:0004467 name: musculature of pharynx namespace: uberon def: "The collection of muscles that acts on the pharynx." [http://orcid.org/0000-0002-6601-2165] comment: See comments for 'pharyngeal muscle' subset: vertebrate_core synonym: "pharyngeal musculature" EXACT [TAO:0001307] synonym: "set of muscles of pharynx" RELATED [FMA:264609] xref: FMA:264609 xref: TAO:0001307 xref: ZFA:0001307 is_a: UBERON:0001015 ! musculature relationship: overlaps UBERON:0001042 ! chordate pharynx [Term] id: UBERON:0004468 name: set of muscles of vertebral column namespace: uberon synonym: "muscle group of vertebral column" EXACT [FMA:33061] xref: FMA:33061 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: attaches_to UBERON:0001130 ! vertebral column relationship: attaches_to UBERON:0001130 ! vertebral column relationship: part_of RO:0002577 ! system [Term] id: UBERON:0004469 name: musculature of back namespace: uberon def: "Any collection of muscles that is part of a back [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of back" EXACT [FMA:71291] synonym: "muscles of back" EXACT [FMA:71291] synonym: "musculi dorsi" EXACT LATIN [FMA:71291, FMA:TA] synonym: "set of muscles of back" EXACT [FMA:71291] xref: FMA:71291 is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0004470 name: musculature of pelvic girdle namespace: uberon alt_id: UBERON:0004485 alt_id: UBERON:0005633 def: "Any collection of muscles that is part of a pelvic girdle [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "muscle group of pelvic girdle" EXACT [FMA:50205] synonym: "muscle group of pelvis" EXACT [FMA:50248] synonym: "muscular system of pelvis" RELATED [FMA:50248] synonym: "pelvic girdle muscle system" EXACT [EHDAA2:0001429] synonym: "pelvic girdle muscles" EXACT [AAO:0000427] synonym: "pelvic girdle musculature" EXACT [FMA:50205] synonym: "set of muscles of pelvic girdle" EXACT [FMA:50205] synonym: "set of muscles of pelvis" RELATED [FMA:50248] xref: AAO:0000427 xref: EHDAA2:0001429 xref: EMAPA:18184 xref: FMA:50205 xref: FMA:50248 is_a: UBERON:0004479 ! musculature of trunk is_a: UBERON:0014792 ! musculature of pelvic complex intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001271 ! pelvic girdle region relationship: part_of UBERON:0001271 ! pelvic girdle region property_value: UBPROP:0000012 "we merge two FMA classes here" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004471 name: musculature of pectoral girdle namespace: uberon def: "A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "muscle group of pectoral girdle" EXACT [FMA:33519] synonym: "pectoral girdle muscles" EXACT [AAO:0000423] synonym: "pectoral girdle musculature" EXACT [FMA:33519] synonym: "set of muscles of pectoral girdle" EXACT [FMA:33519] xref: AAO:0000423 xref: EMAPA:37857 {source="MA:th"} xref: FMA:33519 is_a: UBERON:0014793 ! musculature of pectoral complex intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001421 ! pectoral girdle region relationship: part_of UBERON:0001421 ! pectoral girdle region [Term] id: UBERON:0004473 name: musculature of face namespace: uberon def: "Any collection of muscles that is part of a face." [OBOL:automatic] subset: pheno_slim synonym: "entire facial musculature" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "facial muscles" EXACT [FMA:71288] synonym: "muscle group of face" EXACT [FMA:71288] synonym: "musculi faciei" EXACT LATIN [FMA:71288, FMA:TA] synonym: "set of facial muscles" RELATED [FMA:71288] synonym: "set of muscles of face" RELATED [FMA:71288] xref: FMA:71288 is_a: UBERON:0008229 ! craniocervical region musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001456 ! face relationship: part_of UBERON:0001456 ! face property_value: editor_note "originally created to reflect the distinction drawn in FMA between a facial muscle and the entire musculature of the face. However, naming both does not serve any particular purpose" xsd:string [Term] id: UBERON:0004474 name: musculature of arm namespace: uberon def: "Any collection of muscles that is part of an arm [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "arm muscle system" EXACT [EHDAA2:0000141] synonym: "arm musculature" EXACT [FMA:50202] synonym: "muscle group of arm" EXACT [FMA:50202] synonym: "set of muscles of arm" EXACT [FMA:50202] xref: EHDAA2:0000141 is_a: UBERON:0004481 ! musculature of upper limb intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001460 ! arm relationship: part_of UBERON:0001460 ! arm [Term] id: UBERON:0004475 name: musculature of hip namespace: uberon def: "The collection of muscles that form attachments to the hip skeleton." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "hip musculature" EXACT [FMA:50227] synonym: "muscle group of hip" EXACT [FMA:50227] synonym: "set of muscles of hip" EXACT [FMA:50227] xref: FMA:50227 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: attaches_to UBERON:0008202 ! bone of hip region relationship: attaches_to UBERON:0008202 ! bone of hip region relationship: overlaps UBERON:0001464 ! hip relationship: part_of RO:0002577 ! system [Term] id: UBERON:0004476 name: musculature of shoulder namespace: uberon def: "The collection of muscles that form attachments to the shoulder skeleton." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "muscle group of shoulder" EXACT [FMA:50220] synonym: "set of muscles of shoulder" EXACT [FMA:50220] xref: FMA:50220 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: attaches_to UBERON:0003461 ! shoulder bone relationship: attaches_to UBERON:0003461 ! shoulder bone relationship: overlaps UBERON:0001467 ! shoulder relationship: part_of RO:0002577 ! system [Term] id: UBERON:0004478 name: musculature of larynx namespace: uberon def: "The collection of muscles that are part of the larynx." [http://orcid.org/0000-0002-6601-2165] synonym: "laryngeal muscles" EXACT [FMA:46616] synonym: "laryngeal muscles set" EXACT [FMA:46616] synonym: "muscle group of larynx" EXACT [FMA:46616] synonym: "set of laryngeal muscles" EXACT [FMA:46616] synonym: "set of muscles of larynx" EXACT [FMA:264611] xref: FMA:264611 xref: FMA:46616 xref: MESH:D007821 xref: Wikipedia:Muscles_of_larynx is_a: UBERON:0001015 ! musculature is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001737 ! larynx property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0004479 name: musculature of trunk namespace: uberon def: "Any collection of muscles that is part of a trunk [Automatically generated definition]." [OBOL:automatic] subset: efo_slim subset: pheno_slim synonym: "muscle group of trunk" EXACT [FMA:50187] synonym: "muscular system of trunk" RELATED [FMA:50187] synonym: "set of muscles of trunk" EXACT [FMA:50187] xref: AAO:0011572 xref: EFO:0003531 xref: FMA:50187 is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0004480 name: musculature of limb namespace: uberon alt_id: UBERON:0005635 def: "Any collection of muscles that is part of a limb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "limb muscle system" EXACT [EHDAA2:0000995] synonym: "limb musculature" EXACT [FMA:50188] synonym: "muscle group of limb" EXACT [FMA:50188] synonym: "set of muscles of limb" EXACT [FMA:50188] xref: EHDAA2:0000995 xref: EMAPA:32700 xref: FMA:50188 is_a: UBERON:0007271 ! appendage musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002101 ! limb property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0004481 name: musculature of upper limb namespace: uberon def: "Any collection of muscles that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "free upper limb musculature" EXACT [FMA:50396] synonym: "muscle group of free upper limb" EXACT [FMA:50396] synonym: "musculature of free upper limb" EXACT [FMA:50396] synonym: "set of muscles of free upper limb" EXACT [FMA:50396] xref: FMA:50396 is_a: UBERON:0004480 ! musculature of limb is_a: UBERON:0007269 ! pectoral appendage musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 ! forelimb property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0004482 name: musculature of lower limb namespace: uberon def: "Any collection of muscles that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "free lower limb musculature" EXACT [FMA:50399] synonym: "muscle group of free lower limb" EXACT [FMA:50399] synonym: "musculature of free lower limb" EXACT [FMA:50399] synonym: "set of muscles of free lower limb" EXACT [FMA:50399] xref: FMA:50399 is_a: UBERON:0004480 ! musculature of limb is_a: UBERON:0007270 ! pelvic appendage musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 ! hindlimb property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0004487 name: musculature of forelimb zeugopod namespace: uberon def: "Any collection of muscles that is part of a lower arm [Automatically generated definition]." [OBOL:automatic] synonym: "muscle group of forearm" EXACT [FMA:39089] synonym: "musculature of forearm" EXACT [FMA:39089] synonym: "set of muscles of forearm" EXACT [FMA:39089] xref: FMA:39089 is_a: UBERON:0004474 ! musculature of arm intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002386 ! forelimb zeugopod relationship: part_of UBERON:0002386 ! forelimb zeugopod [Term] id: UBERON:0004488 name: musculature of pes namespace: uberon def: "Any collection of muscles that is part of a foot [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "foot musculature" EXACT [FMA:50214] synonym: "muscle group of foot" EXACT [FMA:50214] synonym: "musculature of foot" EXACT [FMA:50214] synonym: "set of muscles of foot" EXACT [FMA:50214] xref: FMA:50214 is_a: UBERON:0004482 ! musculature of lower limb intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0002387 ! pes property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0004489 name: musculature of manus namespace: uberon def: "Any collection of muscles that is part of a manus [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "hand musculature" EXACT [FMA:42368] synonym: "muscle group of hand" EXACT [FMA:42368] synonym: "musculature of hand" EXACT [FMA:42368] synonym: "set of muscles of hand" EXACT [FMA:42368] xref: FMA:42368 is_a: UBERON:0004481 ! musculature of upper limb intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0002398 ! manus property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0004490 name: cardiac muscle tissue of atrium namespace: uberon def: "A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]." [OBOL:automatic] synonym: "atrial cardiac muscle tissue" EXACT [GO:0055009] synonym: "atrial heart muscle" EXACT [GO:0055009] synonym: "atrial myocardium" RELATED [GO:0055009, GOC:mtg_heart] synonym: "cardiac atrium muscle" EXACT [GO:0055009] xref: FMA:7283 is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002302 ! myocardium of atrium property_value: UBPROP:0000012 "in GO, this is equivalent to the atrial myocardium, but FMA distinguishes these two. Consider merging." xsd:string {external_ontology="GO"} [Term] id: UBERON:0004491 name: cardiac muscle tissue of interatrial septum namespace: uberon def: "A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]." [OBOL:automatic] synonym: "interatrial septum cardiac muscle tissue" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "interatrial septum heart muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "interatrial septum muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "interatrial septum myocardium" EXACT [http://orcid.org/0000-0002-6601-2165] xref: FMA:84083 is_a: UBERON:0004492 ! cardiac muscle tissue of cardiac septum intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002085 ! interatrial septum relationship: part_of UBERON:0002085 ! interatrial septum [Term] id: UBERON:0004492 name: cardiac muscle tissue of cardiac septum namespace: uberon def: "A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac septum cardiac muscle tissue" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "cardiac septum heart muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "cardiac septum muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "cardiac septum myocardium" EXACT [http://orcid.org/0000-0002-6601-2165] xref: FMA:226279 is_a: UBERON:0001133 ! cardiac muscle tissue intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002099 ! cardiac septum relationship: part_of UBERON:0002099 ! cardiac septum [Term] id: UBERON:0004493 name: cardiac muscle tissue of myocardium namespace: uberon def: "A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim xref: EMAPA:32688 xref: FMA:261726 xref: MA:0002441 is_a: UBERON:0001133 ! cardiac muscle tissue intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002349 ! myocardium relationship: part_of UBERON:0002349 {source="MA"} ! myocardium property_value: editor_note "Note placement of MA class based on parthood relationship" xsd:string [Term] id: UBERON:0004495 name: skeletal muscle tissue of diaphragm namespace: uberon def: "A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]." [OBOL:automatic] xref: FMA:261898 is_a: UBERON:0003898 ! skeletal muscle tissue of trunk is_a: UBERON:0004830 ! respiratory system skeletal muscle intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001103 ! diaphragm relationship: part_of UBERON:0001103 ! diaphragm [Term] id: UBERON:0004500 name: skeletal muscle tissue of deltoid namespace: uberon def: "A portion of skeletal muscle tissue that is part of a deltoid [Automatically generated definition]." [OBOL:automatic] synonym: "skeletal muscle tissue of deltoid muscle" RELATED [FMA:261732] xref: FMA:261732 is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001476 ! deltoid relationship: part_of UBERON:0001476 ! deltoid [Term] id: UBERON:0004509 name: skeletal muscle tissue of trapezius namespace: uberon def: "A portion of skeletal muscle tissue that is part of a trapezius [Automatically generated definition]." [OBOL:automatic] synonym: "skeletal muscle tissue of trapezius muscle" RELATED [FMA:261938] xref: FMA:261938 is_a: UBERON:0001134 ! skeletal muscle tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0002380 ! trapezius muscle relationship: part_of UBERON:0002380 ! trapezius muscle [Term] id: UBERON:0004515 name: smooth muscle tissue of bronchiole namespace: uberon def: "A portion of smooth muscle tissue that is part of a bronchiole [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas xref: FMA:261045 is_a: UBERON:0004233 ! lower respiratory tract smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002186 ! bronchiole relationship: part_of UBERON:0002186 ! bronchiole property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004516 name: smooth muscle tissue of terminal bronchiole namespace: uberon def: "A portion of smooth muscle tissue that is part of a terminal bronchiole [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas xref: FMA:261051 is_a: UBERON:0004515 ! smooth muscle tissue of bronchiole intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002187 ! terminal bronchiole relationship: part_of UBERON:0002187 ! terminal bronchiole property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004518 name: muscle of vertebral column namespace: uberon def: "A muscle that is attached to a vertebra of the vertebral column." [https://orcid.org/0000-0002-6601-2165] synonym: "vertebral column muscle" EXACT [FMA:22594] xref: FMA:22594 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0002412 ! vertebra relationship: attaches_to UBERON:0002412 ! vertebra [Term] id: UBERON:0004521 name: vasculature of muscle organ namespace: uberon def: "A vasculature that is part of a muscle organ [Automatically generated definition]." [OBOL:automatic] synonym: "muscular organ vasculature" EXACT [FMA:87123] xref: FMA:87123 is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001630 ! muscle organ relationship: part_of UBERON:0001630 ! muscle organ [Term] id: UBERON:0004522 name: vasculature of musculoskeletal system namespace: uberon def: "A vasculature that is part of a musculoskeletal system [Automatically generated definition]." [OBOL:automatic] xref: FMA:239607 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002204 ! musculoskeletal system relationship: part_of UBERON:0002204 ! musculoskeletal system [Term] id: UBERON:0004525 name: cardiac muscle tissue of trabecula carnea of right ventricle namespace: uberon def: "A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]." [OBOL:automatic] xref: FMA:84429 is_a: UBERON:0003381 ! cardiac muscle of right ventricle is_a: UBERON:0003452 ! trabecula carnea cardiac muscle tissue intersection_of: UBERON:0003452 ! trabecula carnea cardiac muscle tissue intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0006570 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! trabecula carnea of right ventricle [Term] id: UBERON:0004526 name: cardiac muscle tissue of trabecula carnea of left ventricle namespace: uberon def: "A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]." [OBOL:automatic] xref: FMA:84430 is_a: UBERON:0003382 ! cardiac muscle of left ventricle is_a: UBERON:0003452 ! trabecula carnea cardiac muscle tissue intersection_of: UBERON:0003452 ! trabecula carnea cardiac muscle tissue intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0006571 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! trabecula carnea of left ventricle [Term] id: UBERON:0004527 name: alveolar process of maxilla namespace: uberon alt_id: UBERON:0001696 def: "The thickened ridge of bone that contains the tooth sockets on the maxilla." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim synonym: "alveolar margin of maxilla" EXACT [] synonym: "alveolar part of maxilla" EXACT [] synonym: "alveolar process of maxilla" EXACT [] synonym: "alveolar ridge of maxilla" EXACT [] synonym: "lower alveolar ridge" EXACT [] synonym: "maxilla alveolar process" EXACT [] synonym: "pars dentalis of maxilla" EXACT [AAO:0000396] synonym: "posterior alveolar ridge" EXACT [] synonym: "processus alveolaris (maxilla)" EXACT [] synonym: "processus alveolaris maxillae" EXACT LATIN [FMA:52897, FMA:TA] xref: AAO:0000396 xref: FMA:52897 xref: MA:0001492 xref: SCTID:245795005 xref: Wikipedia:Alveolar_process is_a: UBERON:0004103 ! alveolar ridge intersection_of: UBERON:0004103 ! alveolar ridge intersection_of: part_of UBERON:0002397 ! maxilla relationship: part_of UBERON:0002397 ! maxilla property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/71/Gray157.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In humans, the tooth-bearing bones are the maxilla and the mandible. The mineral content of alveolar bone is mostly hydroxyapatite, which is also found in enamel as the main inorganic substance" xsd:string {source="WP"} [Term] id: UBERON:0004529 name: anatomical projection namespace: uberon def: "A projection or outgrowth of tissue from a larger body or organ." [https://github.com/obophenotype/uberon/issues/39, Wikipedia:Process_(anatomy)] subset: common_anatomy subset: upper_level synonym: "anatomical process" BROAD [] synonym: "anatomical protrusion" RELATED [] synonym: "flange" NARROW [VSAO:0000180] synonym: "flanges" NARROW PLURAL [VSAO:0000180] synonym: "lamella" NARROW [VSAO:0000180] synonym: "lamellae" NARROW PLURAL [VSAO:0000180] synonym: "lamina" NARROW [VSAO:0000180] synonym: "laminae" NARROW [VSAO:0000180] synonym: "organ process" NARROW [] synonym: "papilla" NARROW [] synonym: "process" BROAD [VSAO:0000180] synonym: "process of organ" NARROW [] synonym: "processes" NARROW PLURAL [VSAO:0000180] synonym: "processus" EXACT LATIN [FMA:67601, FMA:TA] synonym: "projection" EXACT [] synonym: "projection" NARROW [VSAO:0000180] synonym: "projections" NARROW PLURAL [VSAO:0000180] synonym: "protrusion" RELATED [] synonym: "ridge" NARROW [VSAO:0000180] synonym: "ridges" NARROW PLURAL [VSAO:0000180] synonym: "shelf" NARROW [VSAO:0000180] synonym: "shelves" NARROW PLURAL [VSAO:0000180] synonym: "spine" RELATED [] xref: AAO:0010278 xref: FMA:67601 xref: galen:Ridge xref: HAO:0000822 xref: NCIT:C61549 xref: TAO:0001834 xref: VSAO:0000180 xref: Wikipedia:Process_(anatomy) xref: XAO:0004020 is_a: UBERON:0034768 ! morphological feature relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/wdahdul relationship: part_of UBERON:0000062 ! organ property_value: editor_note "should be declared disjoint from organ, but in some ontologies (e.g. ZFA), structures such as neural spines are classified as bones (and hence organs)" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 property_value: UBPROP:0000001 "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, or tissue.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010278", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000001 "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001834", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "Anatomical structure that is a natural outgrowth, projection, or appendage. A process can be part of a bone, cartilage, tissue, fin, scale, etc.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000180", ontology="VSAO", source="TAO:curator"} [Term] id: UBERON:0004530 name: bony projection namespace: uberon def: "Anatomical projection that is composed of bone tissue." [VSAO:wd] subset: vertebrate_core synonym: "bone process" EXACT [FMA:75433] synonym: "bony projections" RELATED PLURAL [ZFA:0001637] synonym: "projection of bone" EXACT [] xref: FMA:75433 xref: ZFA:0001637 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4100000 ! skeletal element projection intersection_of: UBERON:4100000 ! skeletal element projection intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: composed_primarily_of UBERON:0002481 ! bone tissue relationship: continuous_with UBERON:0004765 ! skeletal element [Term] id: UBERON:0004533 name: left testis namespace: uberon def: "A testis that is in the left side of the genitalia [Automatically generated definition]." [OBOL:automatic] synonym: "left testicle" EXACT [MA:0001746] xref: EMAPA:37370 {source="MA:th"} xref: FMA:7212 xref: MA:0001746 xref: NCIT:C49323 xref: SCTID:367720001 xref: UMLS:C0227998 {source="ncithesaurus:Left_Testis"} is_a: UBERON:0000473 ! testis is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000473 ! testis intersection_of: in_left_side_of UBERON:0000990 ! reproductive system relationship: in_left_side_of UBERON:0000990 ! reproductive system property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004534 name: right testis namespace: uberon def: "A testis that is in the right side of the genitalia [Automatically generated definition]." [OBOL:automatic] synonym: "right testicle" EXACT [MA:0001747] xref: EMAPA:37371 {source="MA:th"} xref: FMA:7211 xref: MA:0001747 xref: NCIT:C49326 xref: SCTID:367719007 xref: UMLS:C0227997 {source="ncithesaurus:Right_Testis"} is_a: UBERON:0000473 ! testis is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000473 ! testis intersection_of: in_right_side_of UBERON:0000990 ! reproductive system relationship: in_right_side_of UBERON:0000990 ! reproductive system property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004535 name: cardiovascular system namespace: uberon def: "Anatomical system that has as its parts the heart and blood vessels." [BTO:0000088] subset: efo_slim subset: pheno_slim subset: uberon_slim subset: vertebrate_core synonym: "CV system" RELATED [BTO:0000088] synonym: "Herz und Gefaesssystem" RELATED [BTO:0000088] xref: AAO:0011001 xref: BILA:0000016 xref: BTO:0000088 xref: CALOHA:TS-1297 xref: EFO:0000791 xref: EHDAA2:0000216 xref: EHDAA:394 xref: EMAPA:16104 xref: EMAPA:16370 xref: EV:0100017 xref: FMA:7161 xref: GAID:467 xref: MA:0000010 xref: MAT:0000016 xref: MESH:D002319 xref: MIAA:0000016 xref: NCIT:C12686 xref: SCTID:278198007 xref: TAO:0000010 xref: UMLS:C0007226 {source="ncithesaurus:Cardiovascular_System"} xref: VHOG:0000302 xref: WikipediaCategory:Cardiovascular_system xref: XAO:0000100 xref: XAO:0001010 xref: ZFA:0000010 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: has_part UBERON:0000948 ! heart intersection_of: has_part UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001009 ! circulatory system relationship: has_part UBERON:0000948 ! heart relationship: has_part UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001009 ! circulatory system property_value: IAO:0000232 "we treat cardiovascular as part of circulatory system, with the latter including other kinds of circulation, including lymph." xsd:string property_value: UBPROP:0000003 "The vessels of the cardiovascular system are as varied as the diverse organs they supply. However, these variations are based on modifications of a fundamental plan of organization common to vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000302", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.451", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004537 name: blood vasculature namespace: uberon def: "A vascular network consisting of blood vessels." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "blood system" RELATED [] synonym: "blood vascular network" EXACT [] synonym: "blood vessel system" RELATED [] synonym: "blood vessels" RELATED [TAO:0001079] synonym: "set of blood vessels" EXACT [] xref: TAO:0001079 xref: ZFA:0001079 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: composed_primarily_of UBERON:0001981 ! blood vessel relationship: composed_primarily_of UBERON:0001981 ! blood vessel property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004538 name: left kidney namespace: uberon def: "A kidney that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim xref: EMAPA:36589 xref: FMA:7205 xref: MA:0001655 xref: NCIT:C34006 xref: SCTID:362209008 xref: UMLS:C0227614 {source="ncithesaurus:Left_Kidney"} is_a: UBERON:0002113 ! kidney intersection_of: UBERON:0002113 ! kidney intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004539 name: right kidney namespace: uberon def: "A kidney that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim xref: EMAPA:36590 xref: FMA:7204 xref: MA:0001683 xref: NCIT:C34005 xref: SCTID:362208000 xref: UMLS:C0227613 {source="ncithesaurus:Right_Kidney"} is_a: UBERON:0002113 ! kidney intersection_of: UBERON:0002113 ! kidney intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004544 name: epididymis epithelium namespace: uberon def: "The layer of secretory cells which lines the epididymis." [MGI:csmith, MP:0004933] subset: pheno_slim synonym: "epididymis epithelium" EXACT [FMA:19153] synonym: "epithelium of epididymis" EXACT [FMA:19153] xref: BTO:0005768 xref: CALOHA:TS-2063 xref: EMAPA:30445 xref: FMA:19153 xref: MA:0002825 is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0012275 ! meso-epithelium is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000485 ! simple columnar epithelium intersection_of: part_of UBERON:0001301 ! epididymis relationship: contributes_to_morphology_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0001301 ! epididymis [Term] id: UBERON:0004548 name: left eye namespace: uberon def: "An eye that is part of a left side of organism [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "left eyeball" EXACT [FMA:12515] synonym: "left orbital part of face" NARROW [FMA:54450] synonym: "left orbital region" NARROW [FMA:54450] xref: EMAPA:37362 {source="MA:th"} xref: FMA:12515 xref: MA:0002949 xref: NCIT:C119334 xref: SCTID:362503005 is_a: UBERON:0000970 ! eye is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000970 ! eye intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004549 name: right eye namespace: uberon def: "An eye that is part of a right side of organism [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "right eyeball" EXACT [FMA:12514] synonym: "right orbital part of face" NARROW [FMA:54449] synonym: "right orbital region" NARROW [FMA:54449] xref: EMAPA:37363 {source="MA:th"} xref: FMA:12514 xref: MA:0002950 xref: NCIT:C119333 xref: SCTID:362502000 is_a: UBERON:0000970 ! eye is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000970 ! eye intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0004552 name: digital artery namespace: uberon def: "An artery that is part of a digit [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37076 {source="MA:th"} xref: MA:0001941 xref: SCTID:181335004 is_a: UBERON:0001637 ! artery is_a: UBERON:0003514 ! limb blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0002544 ! digit relationship: part_of UBERON:0002544 ! digit property_value: editor_note "check part_of - do we need term for digit + metacarpal/tarsal bones?" xsd:string [Term] id: UBERON:0004553 name: forelimb digital artery namespace: uberon def: "A digital artery that is part of a forelimb [Automatically generated definition]." [OBOL:automatic] synonym: "digital artery of manus" EXACT [] synonym: "forelimb digital arteries" EXACT [MA:0001953] synonym: "wing digital artery" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:37210 {source="MA:th"} xref: MA:0001953 xref: SCTID:265791006 is_a: UBERON:0003522 ! manual digit blood vessel is_a: UBERON:0004552 ! digital artery intersection_of: UBERON:0004552 ! digital artery intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0004554 name: hindlimb digital artery namespace: uberon def: "A digital artery that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic] synonym: "digital artery of foot" EXACT [FMA:69713] synonym: "hindlimb digital arteries" EXACT [MA:0001964] xref: EMAPA:37214 {source="MA:th"} xref: FMA:69713 xref: MA:0001964 is_a: UBERON:0003516 ! hindlimb blood vessel is_a: UBERON:0004552 ! digital artery intersection_of: UBERON:0004552 ! digital artery intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0004571 name: systemic arterial system namespace: uberon def: "The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Systemic_circulation#Arteries] subset: pheno_slim synonym: "systemic arterial circulatory system" EXACT [FMA:45623] xref: FMA:45623 xref: Wikipedia:Systemic_circulation#Arteries is_a: UBERON:0007798 {source="MA-inferred"} ! vascular system relationship: part_of UBERON:0004572 ! arterial system [Term] id: UBERON:0004572 name: arterial system namespace: uberon def: "The part of the cardiovascular system consisting of all arteries." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim xref: BTO:0004690 xref: EHDAA2:0000143 xref: EHDAA:396 xref: EMAPA:16201 xref: EMAPA:16371 xref: MA:0002719 xref: SCTID:362030008 xref: VHOG:0000273 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0007798 {source="MA"} ! vascular system relationship: has_member UBERON:0001637 ! artery property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000273", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004573 name: systemic artery namespace: uberon def: "An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Artery#Systemic_arteries] subset: pheno_slim synonym: "systemic arterial subtree" EXACT [FMA:66464] xref: EMAPA:37126 {source="MA:th"} xref: FMA:66464 xref: Wikipedia:Artery#Systemic_arteries is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0004571 ! systemic arterial system relationship: part_of UBERON:0004571 ! systemic arterial system [Term] id: UBERON:0004581 name: systemic venous system namespace: uberon def: "The part of the venous system that drains the general body tissues[Kardong]." [ISBN:0073040584, Wikipedia:Systemic_venous_system] synonym: "systemic venous circulatory system" EXACT [FMA:45626] xref: FMA:45626 xref: Wikipedia:Systemic_venous_system is_a: UBERON:0002049 ! vasculature relationship: part_of UBERON:0004582 ! venous system property_value: UBPROP:0000001 "In human anatomy, the systemic venous system refers to veins that drain into the right atrium without passing through two vascular beds (i.e. they originate from a set of capillaries and do not pass through a second set of capillaries before reaching the right side of the heart). The term systemic venous system is often used to differentiate veins from veins that drain the pulmonary system (the pulmonary venous system) and veins that drain the digestive tract (the portal venous system). Large veins that are considered part of the systemic venous system are the: Superior vena cava; Inferior vena cava[WP]" xsd:string {source="Wikipedia:Systemic_venous_system"} property_value: UBPROP:0000001 "Subdivision of cardiovascular system which has as its parts the right side of heart, the superior vena cava and the inferior vena cava[FMA]" xsd:string {ontology="FMA", source="FMA:45626"} property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000277", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004582 name: venous system namespace: uberon def: "The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions." [https://orcid.org/0000-0002-6601-2165] synonym: "vein system" EXACT [] xref: BTO:0004692 xref: EHDAA2:0002171 xref: EHDAA:486 xref: EMAPA:16240 xref: MA:0002720 xref: NCIT:C33858 xref: SCTID:362060003 xref: UMLS:C1267406 {source="ncithesaurus:Venous_System"} xref: VHOG:0000277 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0007798 {source="MA"} ! vascular system relationship: composed_primarily_of UBERON:0001638 ! vein property_value: UBPROP:0000003 "The appearance of Chordata and subsequently the vertebrates is accompanied by a rapid structural diversification of this primitive linear heart: looping, unidirectional circulation, an enclosed vasculature, and the conduction system.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000277", ontology="VHOG", source="DOI:10.1196/annals.1341.002 Bishopric NH, Evolution of the heart from bacteria to man. Annals of the New York Academy of Sciences (2005)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004590 name: sphincter muscle namespace: uberon def: "A structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." [Wikipedia:Sphincter] synonym: "circular muscle" RELATED [] synonym: "sphincter" EXACT [] xref: FMA:75004 xref: NCIT:C28381 xref: UMLS:C1409894 {source="ncithesaurus:Sphincter"} xref: Wikipedia:Sphincter is_a: UBERON:0001630 ! muscle organ property_value: UBPROP:0000012 "FMA class is not a subtype of muscle" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004612 name: mammalian cervical vertebra 3 namespace: uberon def: "The third of the seven cervical vertebrae[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:C3_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas subset: pheno_slim synonym: "C3 vertebra" EXACT [FMA:12521] synonym: "cervical vertebra 3" EXACT [MA:0001423] synonym: "cervical vertebrae 3" EXACT [UBERONTEMP:aeb6ac70-fd18-403d-a0b9-dd03942c7812] synonym: "third cervical vertebra" EXACT [FMA:12521] synonym: "third cervical vertebra of axial skeleton" EXACT [UBERONTEMP:aeb6ac70-fd18-403d-a0b9-dd03942c7812] xref: EMAPA:19433 xref: FMA:12521 xref: MA:0001423 xref: NCIT:C32241 xref: SCTID:181823007 xref: UMLS:C0459939 {source="ncithesaurus:C3_Vertebra"} is_a: UBERON:0002413 ! cervical vertebra relationship: anteriorly_connected_to UBERON:0001093 {source="FMA"} ! vertebral bone 2 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia property_value: editor_note "under discussion: whether to generalize this beyond mammals, making it purely order-defined" xsd:string property_value: IAO:0000232 "elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000107 "3" xsd:nonNegativeInteger [Term] id: UBERON:0004613 name: mammalian cervical vertebra 4 namespace: uberon def: "The fourth of the seven cervical vertebrae[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:C4_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas subset: pheno_slim synonym: "C4 vertebra" EXACT [FMA:12522] synonym: "cervical vertebra 4" EXACT [MA:0001424] synonym: "fourth cervical vertebra" EXACT [FMA:12522] xref: EMAPA:19434 xref: FMA:12522 xref: MA:0001424 xref: NCIT:C32242 xref: SCTID:181824001 xref: UMLS:C0459941 {source="ncithesaurus:C4_Vertebra"} is_a: UBERON:0002413 ! cervical vertebra relationship: anteriorly_connected_to UBERON:0004612 {source="FMA"} ! mammalian cervical vertebra 3 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia property_value: IAO:0000232 "elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000107 "4" xsd:nonNegativeInteger [Term] id: UBERON:0004614 name: mammalian cervical vertebra 5 namespace: uberon def: "The fifth of the seven cervical vertebrae[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:C5_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas subset: pheno_slim synonym: "C5 vertebra" EXACT [FMA:12523] synonym: "cervical vertebra 5" EXACT [MA:0001425] synonym: "fifth cervical vertebra" EXACT [FMA:12523] xref: EMAPA:19435 xref: FMA:12523 xref: MA:0001425 xref: NCIT:C32243 xref: SCTID:181825000 xref: UMLS:C0459943 {source="ncithesaurus:C5_Vertebra"} is_a: UBERON:0002413 ! cervical vertebra relationship: anteriorly_connected_to UBERON:0004613 {source="FMA"} ! mammalian cervical vertebra 4 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia property_value: IAO:0000232 "elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000107 "5" xsd:nonNegativeInteger [Term] id: UBERON:0004615 name: mammalian cervical vertebra 6 namespace: uberon def: "The sixth of the seven cervical vertebrae[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:C6_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas subset: pheno_slim synonym: "C6 vertebra" EXACT [FMA:12524] synonym: "cervical vertebra 6" EXACT [MA:0001426] synonym: "sixth cervical vertebra" EXACT [FMA:12524] xref: EMAPA:19466 xref: FMA:12524 xref: MA:0001426 xref: NCIT:C32244 xref: SCTID:181826004 xref: UMLS:C0459944 {source="ncithesaurus:C6_Vertebra"} is_a: UBERON:0002413 ! cervical vertebra relationship: anteriorly_connected_to UBERON:0004614 {source="FMA"} ! mammalian cervical vertebra 5 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia property_value: IAO:0000232 "elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000107 "6" xsd:nonNegativeInteger [Term] id: UBERON:0004616 name: mammalian cervical vertebra 7 namespace: uberon def: "Vertebra prominens is the proper name for the seventh cervical vertebra. The most distinctive characteristic of this vertebra is the existence of a long and prominent spinous process which is palpable from the skin surface, hence the name. This spinous process is thick, nearly horizontal in direction, not bifurcated, but terminating in a tubercle to which the lower end of the ligamentum nuchae is attached. The seventh cervical vertebra (C7) has the most prominent spinous process only in about 70% of people; in the remainder, either C6 or T1 (the first thoracic vertebra) will be the most prominent. The transverse processes are of considerable size, their posterior roots are large and prominent, while the anterior are small and faintly marked; the upper surface of each has usually a shallow sulcus for the eighth spinal nerve, and its extremity seldom presents more than a trace of bifurcation. The foramen transversarium may be as large as that in the other cervical vertebrae, but is generally smaller on one or both sides; occasionally it is double, sometimes it is absent. On the left side it occasionally gives passage to the vertebral artery; more frequently the vertebral vein traverses it on both sides; but the usual arrangement is for both artery and vein to pass in front of the transverse process, and not through the foramen. Sometimes the anterior root of the transverse process attains a large size and exists as a separate bone, which is known as a cervical rib." [Wikipedia:Vertebra_prominens] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "C7 vertebra" EXACT [FMA:12525] synonym: "cervical vertebra 7" EXACT [MA:0001427] synonym: "prominent vertebra" EXACT [FMA:12525] synonym: "seventh cervical vertebra" EXACT [FMA:12525] synonym: "vertebra prominens (CVII)" EXACT [FMA:12525] synonym: "vertebra prominens [C VII]" EXACT LATIN [FMA:12525, FMA:TA] xref: EMAPA:19467 xref: FMA:12525 xref: MA:0001427 xref: NCIT:C32245 xref: SCTID:181827008 xref: UMLS:C0223176 {source="ncithesaurus:C7_Vertebra"} xref: Wikipedia:Vertebra_prominens is_a: UBERON:0002413 ! cervical vertebra relationship: anteriorly_connected_to UBERON:0004615 {source="FMA"} ! mammalian cervical vertebra 6 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia property_value: IAO:0000232 "elements are to be defined spatially/topologically. all mammals have 7 cervical vertebrae" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000107 "7" xsd:nonNegativeInteger [Term] id: UBERON:0004617 name: lumbar vertebra 1 namespace: uberon def: "The first lumbar vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:L1_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "first lumbar vertebra" EXACT [FMA:13072] synonym: "L1 vertebra" EXACT [FMA:13072] xref: EMAPA:19472 xref: FMA:13072 xref: MA:0001428 xref: NCIT:C32899 xref: SCTID:181841004 xref: UMLS:C0223492 {source="ncithesaurus:L1_Vertebra"} is_a: UBERON:0002414 ! lumbar vertebra relationship: anteriorly_connected_to UBERON:0004636 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! thoracic vertebra 12 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004618 name: lumbar vertebra 2 namespace: uberon def: "The second lumbar vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:L2_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas subset: pheno_slim synonym: "L2 vertebra" EXACT [FMA:13073] synonym: "second lumbar vertebra" EXACT [FMA:13073] xref: EMAPA:19570 xref: FMA:13073 xref: MA:0001429 xref: NCIT:C32900 xref: SCTID:181842006 xref: UMLS:C0223507 {source="ncithesaurus:L2_Vertebra"} is_a: UBERON:0002414 ! lumbar vertebra relationship: anteriorly_connected_to UBERON:0004617 {source="FMA"} ! lumbar vertebra 1 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004619 name: lumbar vertebra 3 namespace: uberon def: "The third lumbar vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:L3_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas subset: pheno_slim synonym: "L3 vertebra" EXACT [FMA:13074] synonym: "third lumbar vertebra" EXACT [FMA:13074] xref: EMAPA:19571 xref: FMA:13074 xref: MA:0001430 xref: NCIT:C32901 xref: SCTID:181843001 xref: UMLS:C0223522 {source="ncithesaurus:L3_Vertebra"} is_a: UBERON:0002414 ! lumbar vertebra relationship: anteriorly_connected_to UBERON:0004618 {source="FMA"} ! lumbar vertebra 2 relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004620 name: lumbar vertebra 4 namespace: uberon def: "The fourth lumbar vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:L4_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "fourth lumbar vertebra" EXACT [FMA:13075] synonym: "L4 vertebra" EXACT [FMA:13075] xref: EMAPA:19572 xref: FMA:13075 xref: MA:0001431 xref: NCIT:C32902 xref: SCTID:181844007 xref: UMLS:C0223537 {source="ncithesaurus:L4_Vertebra"} is_a: UBERON:0002414 ! lumbar vertebra relationship: anteriorly_connected_to UBERON:0004619 {source="FMA"} ! lumbar vertebra 3 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004621 name: lumbar vertebra 5 namespace: uberon def: "The fifth lumbar vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:L5_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas subset: pheno_slim synonym: "fifth lumbar vertebra" EXACT [FMA:13076] synonym: "L5 vertebra" EXACT [FMA:13076] xref: EMAPA:19573 xref: FMA:13076 xref: MA:0001432 xref: NCIT:C32903 xref: SCTID:181845008 xref: UMLS:C0223552 {source="ncithesaurus:L5_Vertebra"} is_a: UBERON:0002414 ! lumbar vertebra relationship: anteriorly_connected_to UBERON:0004620 {source="FMA"} ! lumbar vertebra 4 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004622 name: sacral vertebra 1 namespace: uberon subset: defined_by_ordinal_series synonym: "first sacral segment" EXACT [FMA:13077] synonym: "first sacral vertebra" EXACT [FMA:13077] synonym: "first segment of sacrum" EXACT [FMA:13077] synonym: "S1 vertebra" EXACT [FMA:13077] xref: EMAPA:19588 xref: FMA:13077 xref: MA:0001434 xref: NCIT:C33498 xref: SCTID:181846009 xref: UMLS:C0223598 {source="ncithesaurus:S1_Vertebra"} is_a: UBERON:0001094 ! sacral vertebra property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string [Term] id: UBERON:0004623 name: sacral vertebra 2 namespace: uberon subset: defined_by_ordinal_series synonym: "S2 vertebra" EXACT [FMA:13078] synonym: "second sacral segment" EXACT [FMA:13078] synonym: "second sacral vertebra" EXACT [FMA:13078] synonym: "second segment of sacrum" EXACT [FMA:13078] xref: EMAPA:19589 xref: FMA:13078 xref: MA:0001435 xref: NCIT:C33499 xref: SCTID:181847000 xref: UMLS:C0223599 {source="ncithesaurus:S2_Vertebra"} is_a: UBERON:0001094 ! sacral vertebra property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string [Term] id: UBERON:0004624 name: sacral vertebra 3 namespace: uberon subset: defined_by_ordinal_series synonym: "S3 vertebra" EXACT [FMA:13079] synonym: "third sacral segment" EXACT [FMA:13079] synonym: "third sacral vertebra" EXACT [FMA:13079] synonym: "third segment of sacrum" EXACT [FMA:13079] xref: EMAPA:19590 xref: FMA:13079 xref: MA:0001436 xref: NCIT:C33500 xref: SCTID:181848005 xref: UMLS:C0223600 {source="ncithesaurus:S3_Vertebra"} is_a: UBERON:0001094 ! sacral vertebra property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string [Term] id: UBERON:0004625 name: sacral vertebra 4 namespace: uberon subset: defined_by_ordinal_series synonym: "fourth sacral segment" EXACT [FMA:13080] synonym: "fourth sacral vertebra" EXACT [FMA:13080] synonym: "fourth segment of sacrum" EXACT [FMA:13080] synonym: "S4 vertebra" EXACT [FMA:13080] xref: EMAPA:19591 xref: FMA:13080 xref: MA:0001437 xref: NCIT:C33501 xref: SCTID:181849002 xref: UMLS:C0223601 {source="ncithesaurus:S4_Vertebra"} is_a: UBERON:0001094 ! sacral vertebra property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string [Term] id: UBERON:0004626 name: thoracic vertebra 1 namespace: uberon def: "The first thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T1_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "first dorsal vertebra" EXACT [FMA:9165] synonym: "first thoracic vertebra" EXACT [FMA:9165] synonym: "T1 vertebra" EXACT [FMA:9165] xref: EMAPA:19542 xref: FMA:9165 xref: MA:0001438 xref: NCIT:C33720 xref: SCTID:181828003 xref: UMLS:C0459933 {source="ncithesaurus:T1_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004616 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! mammalian cervical vertebra 7 property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004627 name: thoracic vertebra 2 namespace: uberon def: "The second thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T2_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "second dorsal vertebra" EXACT [FMA:9187] synonym: "second thoracic vertebra" EXACT [FMA:9187] synonym: "T2 vertebra" EXACT [FMA:9187] xref: EMAPA:19543 xref: FMA:9187 xref: MA:0001439 xref: NCIT:C33724 xref: SCTID:181829006 xref: UMLS:C0459936 {source="ncithesaurus:T2_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004626 {source="FMA"} ! thoracic vertebra 1 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004628 name: thoracic vertebra 3 namespace: uberon def: "The third thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T3_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "T3 vertebra" EXACT [FMA:9209] synonym: "third dorsal vertebra" EXACT [FMA:9209] synonym: "third thoracic vertebra" EXACT [FMA:9209] xref: EMAPA:19544 xref: FMA:9209 xref: MA:0001440 xref: NCIT:C33725 xref: SCTID:181830001 xref: UMLS:C0459952 {source="ncithesaurus:T3_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004627 {source="FMA"} ! thoracic vertebra 2 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004629 name: thoracic vertebra 4 namespace: uberon def: "The fourth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T4_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "fourth dorsal vertebra" EXACT [FMA:9248] synonym: "fourth thoracic vertebra" EXACT [FMA:9248] synonym: "T4 vertebra" EXACT [FMA:9248] xref: EMAPA:19545 xref: FMA:9248 xref: MA:0001441 xref: NCIT:C33726 xref: SCTID:181831002 xref: UMLS:C0459951 {source="ncithesaurus:T4_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004628 {source="FMA"} ! thoracic vertebra 3 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004630 name: thoracic vertebra 5 namespace: uberon def: "The fifth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T5_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "fifth dorsal vertebra" EXACT [FMA:9922] synonym: "fifth thoracic vertebra" EXACT [FMA:9922] synonym: "T5 vertebra" EXACT [FMA:9922] xref: EMAPA:19546 xref: FMA:9922 xref: MA:0001442 xref: NCIT:C33727 xref: SCTID:181832009 xref: UMLS:C0459950 {source="ncithesaurus:T5_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004629 {source="FMA"} ! thoracic vertebra 4 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004631 name: thoracic vertebra 6 namespace: uberon def: "The sixth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T6_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "sixth dorsal vertebra" EXACT [FMA:9945] synonym: "sixth thoracic vertebra" EXACT [FMA:9945] synonym: "T6 vertebra" EXACT [FMA:9945] xref: EMAPA:19547 xref: FMA:9945 xref: MA:0001443 xref: NCIT:C33728 xref: SCTID:181834005 xref: UMLS:C0459949 {source="ncithesaurus:T6_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004630 {source="FMA"} ! thoracic vertebra 5 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004632 name: thoracic vertebra 7 namespace: uberon def: "The seventh thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T7_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "seventh dorsal vertebra" EXACT [FMA:9968] synonym: "seventh thoracic vertebra" EXACT [FMA:9968] synonym: "T7 vertebra" EXACT [FMA:9968] xref: EMAPA:19548 xref: FMA:9968 xref: MA:0001444 xref: NCIT:C33729 xref: SCTID:181835006 xref: UMLS:C0459947 {source="ncithesaurus:T7_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004631 {source="FMA"} ! thoracic vertebra 6 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004633 name: thoracic vertebra 9 namespace: uberon def: "The ninth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T9_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "Ninth dorsal vertebra" EXACT [FMA:10014] synonym: "ninth thoracic vertebra" EXACT [FMA:10014] synonym: "T9 vertebra" EXACT [FMA:10014] xref: EMAPA:19550 xref: FMA:10014 xref: MA:0001446 xref: NCIT:C33731 xref: SCTID:181837003 xref: UMLS:C0459954 {source="ncithesaurus:T9_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0011050 {source="FMA"} ! thoracic vertebra 8 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004634 name: thoracic vertebra 10 namespace: uberon def: "The tenth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T10_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "T10 vertebra" EXACT [FMA:10037] synonym: "tenth dorsal vertebra" EXACT [FMA:10037] synonym: "tenth thoracic vertebra" EXACT [FMA:10037] xref: EMAPA:19551 xref: FMA:10037 xref: MA:0001447 xref: NCIT:C33721 xref: SCTID:181838008 xref: UMLS:C0459955 {source="ncithesaurus:T10_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004633 {source="FMA"} ! thoracic vertebra 9 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004635 name: thoracic vertebra 11 namespace: uberon def: "The eleventh thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T11_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "eleventh dorsal vertebra" EXACT [FMA:10059] synonym: "eleventh thoracic vertebra" EXACT [FMA:10059] synonym: "T11 vertebra" EXACT [FMA:10059] xref: EMAPA:19552 xref: FMA:10059 xref: MA:0001448 xref: NCIT:C33722 xref: SCTID:181839000 xref: UMLS:C0459956 {source="ncithesaurus:T11_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004634 {source="FMA"} ! thoracic vertebra 10 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004636 name: thoracic vertebra 12 namespace: uberon def: "The twelfth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T12_Vertebra] subset: defined_by_ordinal_series subset: human_reference_atlas synonym: "T12 vertebra" EXACT [FMA:10081] synonym: "twelfth dorsal vertebra" EXACT [FMA:10081] synonym: "twelfth thoracic vertebra" EXACT [FMA:10081] xref: EMAPA:19553 xref: FMA:10081 xref: MA:0001449 xref: NCIT:C33723 xref: SCTID:181840003 xref: UMLS:C0459957 {source="ncithesaurus:T12_Vertebra"} is_a: UBERON:0002347 ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004635 {source="FMA"} ! thoracic vertebra 11 relationship: part_of RO:0002577 ! system property_value: IAO:0000232 "elements are to be defined spatially/topologically" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004638 name: blood vessel endothelium namespace: uberon def: "An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: vertebrate_core xref: BTO:0000766 xref: CALOHA:TS-2155 xref: EMAPA:35176 xref: MA:0000709 xref: NCIT:C53395 xref: TAO:0005257 xref: UMLS:C1706972 {source="ncithesaurus:Blood_Vessel_Endothelium"} xref: ZFA:0005257 is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel [Term] id: UBERON:0004647 name: liver lobule namespace: uberon def: "The polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein." [ISBN:0-683-40008-8, MP:0008987] subset: human_reference_atlas subset: pheno_slim synonym: "hepatic lobule" EXACT [FMA:14471] synonym: "lobules of liver" RELATED PLURAL [Wikipedia:Lobules_of_liver] synonym: "lobuli hepatici" EXACT PLURAL [] synonym: "lobuli hepatis" RELATED LATIN [Wikipedia:Lobules_of_liver] synonym: "lobulus hepaticus" EXACT LATIN [FMA:14471] xref: EMAPA:35499 xref: FMA:14471 xref: MA:0002494 xref: NCIT:C32732 xref: SCTID:362194004 xref: UMLS:C0227518 {source="ncithesaurus:Hepatic_Lobule"} xref: Wikipedia:Lobules_of_liver is_a: UBERON:0000064 {source="FMA"} ! organ part is_a: UBERON:0004119 ! endoderm-derived structure relationship: contributes_to_morphology_of UBERON:0001280 ! liver parenchyma relationship: has_part CL:0000182 ! hepatocyte relationship: part_of UBERON:0001280 {source="FMA", source="MA"} ! liver parenchyma property_value: IAO:0000232 "should not be confused with the anatomic lobes of the liver (caudate lobe, quadrate lobe, left lobe, and right lobe), or any of the functional lobe classification systems.[WP]" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004650 name: tongue keratinized epithelium namespace: uberon def: "A keratinized stratified squamous epithelium that is part of a tongue." [OBOL:automatic] synonym: "keratinized epithelium of tongue" EXACT [FMA:74865] xref: FMA:74865 xref: MA:0002787 is_a: UBERON:0006919 ! tongue squamous epithelium is_a: UBERON:0012329 ! keratinized stratified squamous epithelium intersection_of: UBERON:0012329 ! keratinized stratified squamous epithelium intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0004651 name: scapula spine namespace: uberon def: "The triangular ridge on the dorsal aspect of the scapula which separates the supra- from the infraspinatous fossa and where the trapezius and deltoid muscles are attached." [ISBN:0-683-40008-8, MP:0004347] subset: pheno_slim synonym: "scapular spine" RELATED [FMA:13453, MA:0002806] synonym: "spina scapulae" RELATED LATIN [Wikipedia:Spine_of_scapula] synonym: "spine of scapula" EXACT [FMA:13453] xref: EMAPA:25123 xref: FMA:13453 xref: MA:0002806 xref: SCTID:181916005 xref: Wikipedia:Spine_of_scapula is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ relationship: part_of UBERON:0006849 ! scapula property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a6/Gray205_left_scapula_lateral_view.png" xsd:anyURI property_value: UBPROP:0000003 "homology debated" xsd:string {is_about="UBERON:0004741", source="PMC1352163", status="not_accepted"} property_value: UBPROP:0000003 "the cleithrum, the major shoulder bone of extinct land vertebrate ancestors,.. appears to survive as the scapular spine in living mammals[Matsuoka, PMC1352163]" xsd:string {is_about="UBERON:0004741", source="PMC1352163", status="not_accepted"} [Term] id: UBERON:0004652 name: humerus diaphysis namespace: uberon def: "The body or shaft of the humerus is almost cylindrical in the upper half of its extent, prismatic and flattened below, and has three borders and three surfaces." [Wikipedia:Body_of_humerus] subset: pheno_slim synonym: "body of humerus" EXACT [FMA:13305] synonym: "body of the humerus" RELATED [Wikipedia:Body_of_humerus] synonym: "corpus humeri" EXACT LATIN [FMA:13305, FMA:TA] synonym: "diaphysis of humerus" EXACT [FMA:13305] synonym: "humeral diaphysis" EXACT [FMA:13305] synonym: "medial humerus" RELATED [Wikipedia:Body_of_humerus] synonym: "shaft of humerus" EXACT [FMA:13305] synonym: "shaft of the humerus" RELATED [Wikipedia:Body_of_humerus] xref: EMAPA:25051 xref: FMA:13305 xref: MA:0002807 xref: NCIT:C120671 xref: SCTID:181927007 xref: Wikipedia:Body_of_humerus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0000976 ! humerus relationship: part_of UBERON:0000976 ! humerus [Term] id: UBERON:0004663 name: aorta wall namespace: uberon def: "An anatomical wall that is part of an aorta, enclosing the luminal space." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "aortic wall" EXACT [FMA:14156] synonym: "wall of aorta" EXACT [FMA:14156] xref: EMAPA:35139 xref: FMA:14156 xref: MA:0002901 is_a: UBERON:0035965 ! wall of blood vessel intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000947 ! aorta relationship: contributes_to_morphology_of UBERON:0000947 ! aorta relationship: part_of UBERON:0000947 ! aorta [Term] id: UBERON:0004664 name: aorta tunica adventitia namespace: uberon def: "The outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers." [ISBN:0-683-40008-8, MP:0009871] subset: pheno_slim synonym: "tunica adventitia of aorta" EXACT [FMA:14283] xref: EMAPA:35136 xref: FMA:14283 xref: MA:0002902 xref: SCTID:24996002 is_a: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: part_of UBERON:0000947 ! aorta relationship: contributes_to_morphology_of UBERON:0004663 ! aorta wall relationship: part_of UBERON:0004663 ! aorta wall [Term] id: UBERON:0004665 name: muscular coat of seminal vesicle namespace: uberon def: "A muscular coat that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic] synonym: "muscle layer of seminal vesicle" EXACT [FMA:19404] synonym: "muscular coat of seminal gland" EXACT [FMA:19404] synonym: "muscular layer of seminal gland" EXACT [FMA:19404] synonym: "tunica muscularis (vesicula seminalis)" EXACT [FMA:19404] synonym: "tunica muscularis glandulae vesiculosae" EXACT LATIN [FMA:19404, FMA:TA] xref: EMAPA:29773 xref: FMA:19404 xref: MA:0002913 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0006660 ! muscular coat intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: part_of UBERON:0000998 ! seminal vesicle [Term] id: UBERON:0004666 name: interventricular septum membranous part namespace: uberon alt_id: UBERON:0004143 def: "The membranous portion of the wall between the two lower chambers of the heart." [MP:0008823] subset: pheno_slim synonym: "cardiac ventricular membranous septum" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "membranous interventricular septum" EXACT [FMA:7135] synonym: "membranous interventricular septum" RELATED [MA:0002939] synonym: "membranous part interventricular septum" EXACT [VHOG:0000927] synonym: "membranous part of interventricular septum" EXACT [FMA:7135] synonym: "membranous portion of interventricular septum" EXACT [FMA:7135] synonym: "membranous septum" BROAD [GO:0003149] synonym: "pars membranacea (septi interventricularis)" EXACT [FMA:7135] synonym: "pars membranacea septi interventricularis" EXACT LATIN [FMA:7135, FMA:TA] synonym: "ventricle membranous septum" BROAD [VT:0000018] synonym: "ventricular membranous septum" BROAD [MP:0008823] xref: EHDAA2:0004596 xref: EMAPA:18246 xref: FMA:7135 xref: MA:0002939 xref: SCTID:278228007 xref: VHOG:0000927 is_a: UBERON:0000158 ! membranous layer is_a: UBERON:0005983 ! heart layer is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0000158 ! membranous layer intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: contributes_to_morphology_of UBERON:0002094 ! interventricular septum relationship: develops_from UBERON:0000095 {source="Wikipedia"} ! cardiac neural crest relationship: part_of UBERON:0002094 ! interventricular septum property_value: UBPROP:0000001 "The membranous septum is the upper part of ventricular septum[GO:0003149]." xsd:string {source="GO:0003149"} [Term] id: UBERON:0004667 name: interventricular septum muscular part namespace: uberon alt_id: UBERON:0004144 def: "The muscular portion of the wall between the two lower chambers of the heart." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Interventricular_septum#Portions] subset: pheno_slim synonym: "cardiac ventricular muscular septum" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "muscular interventricular septum" EXACT [FMA:7134] synonym: "muscular interventricular septum" RELATED [MA:0002940] synonym: "muscular part interventricular septum" EXACT [] synonym: "muscular part of interventricular septum" EXACT [FMA:7134] synonym: "muscular septum" BROAD [GO:0003150] synonym: "pars muscularis (septi interventricularis)" EXACT [FMA:7134] synonym: "pars muscularis septi interventricularis" EXACT LATIN [FMA:7134, FMA:TA] synonym: "septum membranaceum" EXACT LATIN [] synonym: "ventricular muscular septum" EXACT [] xref: EHDAA2:0000885 xref: EHDAA:2607 xref: EMAPA:18247 xref: FMA:7134 xref: MA:0002940 xref: RETIRED_EHDAA2:0000888 is_a: UBERON:0002385 ! muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: contributes_to_morphology_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum property_value: UBPROP:0000001 "The muscular septum is the lower part of the ventricular septum[GO]" xsd:string {source="GO:0003150"} [Term] id: UBERON:0004684 name: raphe nuclei namespace: uberon def: "The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane." [https://sourceforge.net/tracker/?func=detail&aid=3248146&group_id=36855&atid=440764, NLXANAT:20090205] comment: we treat NR obscurus, NR magnus etc as parts of the raphe nuclei. This is consistent with treatment in FMA, where the class is 'set of raphe nuclei' subset: vertebrate_core synonym: "nuclei raphes" EXACT LATIN [FMA:84017, FMA:TA] synonym: "nuclei raphes" RELATED LATIN [Wikipedia:Raphe_nuclei] synonym: "raphe cluster" RELATED [Wikipedia:Raphe_nuclei] synonym: "raphe nuclei" EXACT [FMA:84017, NLXANAT:20090205] synonym: "raphe nuclei set" EXACT [FMA:84017] synonym: "raphe nucleus" RELATED [ZFA:0001429] synonym: "raphe of mesenchephalon" RELATED [BAMS:RA] synonym: "set of raphe nuclei" RELATED [FMA:84017] xref: BAMS:RA xref: EMAPA:35721 xref: FMA:84017 xref: MA:0003147 xref: MESH:D011903 xref: NCIT:C97335 xref: neuronames:2495 xref: NLXANAT:20090205 xref: TAO:0001429 xref: UMLS:C0034671 {source="ncithesaurus:Raphe_Nuclei"} xref: Wikipedia:Raphe_nuclei xref: ZFA:0001429 is_a: UBERON:0002616 ! regional part of brain relationship: capable_of GO:0001820 {source="Wikipedia"} ! serotonin secretion relationship: part_of UBERON:0002275 {source="GO", source="Wikipedia"} ! reticular formation property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.png" xsd:anyURI [Term] id: UBERON:0004688 name: costo-cervical trunk namespace: uberon def: "The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]." [Wikipedia:Costocervical_trunk] subset: human_reference_atlas synonym: "costocervical trunk" EXACT [FMA:10636] synonym: "truncus costocervicalis" RELATED LATIN [Wikipedia:Costocervical_trunk] synonym: "trunk of costocervical artery" EXACT [FMA:10636] xref: EMAPA:37496 {source="MA:th"} xref: FMA:10636 xref: MA:0001939 xref: SCTID:244225009 xref: Wikipedia:Costocervical_trunk is_a: UBERON:0001637 ! artery relationship: connected_to UBERON:0001533 ! subclavian artery relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b3/Costocervical_trunk_with_branches.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004692 name: external naris epithelium namespace: uberon def: "An epithelium that is part of an external naris [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:18596 xref: MA:0001321 is_a: UBERON:0019306 ! nose epithelium is_a: UBERON:0035036 ! naris epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005928 ! external naris relationship: part_of UBERON:0005928 ! external naris [Term] id: UBERON:0004695 name: arterial system smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:36503 xref: MA:0000704 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0004572 ! arterial system relationship: part_of UBERON:0004572 ! arterial system [Term] id: UBERON:0004696 name: venous system smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:36613 xref: MA:0000715 is_a: UBERON:0004237 ! blood vessel smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0004582 ! venous system relationship: part_of UBERON:0004237 ! blood vessel smooth muscle relationship: part_of UBERON:0004582 ! venous system [Term] id: UBERON:0004698 name: vena cava endothelium namespace: uberon def: "An endothelium that is part of a vena cava [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37800 {source="MA:th"} xref: MA:0000713 xref: NCIT:C49318 xref: UMLS:C1710623 {source="ncithesaurus:Vena_Cava_Endothelium"} is_a: UBERON:0001919 ! endothelium of vein intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004087 ! vena cava relationship: part_of UBERON:0004087 ! vena cava [Term] id: UBERON:0004699 name: outflow tract endothelium namespace: uberon def: "An endothelium that is part of a outflow tract [Automatically generated definition]." [OBOL:automatic] xref: MA:0000490 xref: VHOG:0001524 is_a: UBERON:0008307 ! heart endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004145 ! outflow tract relationship: part_of UBERON:0004145 ! outflow tract property_value: UBPROP:0000003 "It is assumed that during evolution, a circulatory system composed of the heart and endothelial tubular system first formed in vertebrates, medial smooth muscle then appeared for regulation of the system, and innervation of the muscle tissue took place. This sequence of development assumed for phylogenesis is actually realized in the ontogenetic processes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001524", ontology="VHOG", source="DOI:10.1254/jjp.87.253 Shigei T, Tsuru H, Ishikawa N, Yoshioka K, Absence of endothelium in invertebrate blood vessels: significance of endothelium and sympathetic nerve/medial smooth muscle in the vertebrate vascular system. Japanese Journal of Pharmacology (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004700 name: arterial system endothelium namespace: uberon def: "An endothelium that is part of an arterial system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:35145 xref: MA:0000703 xref: NCIT:C49329 xref: UMLS:C1706849 {source="ncithesaurus:Arterial_System_Endothelium"} is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004572 ! arterial system relationship: part_of UBERON:0004572 ! arterial system [Term] id: UBERON:0004701 name: venous system endothelium namespace: uberon def: "An endothelium that is part of a venous system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:35907 xref: MA:0000714 xref: NCIT:C49320 xref: UMLS:C1710626 {source="ncithesaurus:Venous_System_Endothelium"} is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004582 ! venous system relationship: part_of UBERON:0004582 ! venous system [Term] id: UBERON:0004702 name: respiratory system blood vessel endothelium namespace: uberon def: "A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:35732 xref: MA:0001805 is_a: UBERON:0004638 ! blood vessel endothelium is_a: UBERON:0004807 ! respiratory system epithelium intersection_of: UBERON:0004638 ! blood vessel endothelium intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003504 ! respiratory system blood vessel [Term] id: UBERON:0004704 name: bone fossa namespace: uberon def: "A depression or hollow in a bone[WP]." [Wikipedia:Fossa#Anatomy] subset: vertebrate_core synonym: "concavities" RELATED PLURAL [TAO:0001743] synonym: "concavity" RELATED [TAO:0001743] synonym: "depression" RELATED [TAO:0001743] synonym: "depressions" RELATED PLURAL [TAO:0001743] synonym: "fossa" BROAD [] synonym: "fossae" RELATED PLURAL [TAO:0001743] synonym: "groove" RELATED [TAO:0001743] xref: AAO:0010439 xref: FMA:45791 xref: TAO:0001743 xref: UMLS:C0836913 {source="ncithesaurus:Fossa"} xref: VSAO:0005069 xref: Wikipedia:Fossa#Anatomy xref: ZFA:0005388 is_a: UBERON:0002553 {source="FMA-implied"} ! anatomical cavity relationship: part_of UBERON:0001474 ! bone element property_value: UBPROP:0000001 "Anatomical space that is a concavity, shallow depression, or groove on a bone.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001743", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000012 "General Anatomical term in FMA; not restricted to bone in ncit; surface feature in VSAO; note that entities named 'fossa' are cavities in FMA, hence placement here" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004706 name: bulbus cordis namespace: uberon def: "A transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches." [ISBN:0-683-40008-8, MP:0010568] subset: pheno_slim subset: vertebrate_core synonym: "primitive right ventricle endocardium" EXACT [EHDAA2:0000197] xref: EHDAA2:0000197 xref: EHDAA:438 xref: EHDAA:768 xref: EMAPA:16333 xref: FMA:70300 xref: NCIT:C34114 xref: SCTID:361525002 xref: UMLS:C1284055 {source="ncithesaurus:Bulbus_Cordis"} xref: Wikipedia:Bulbus_cordis is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000948 ! heart property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/c9/Gray466.png" xsd:anyURI property_value: editor_note "TODO - check relationship to bulbus arteriosus" xsd:string property_value: UBPROP:0000001 "A pear shaped chamber that functions as a capacitor, maintaining continuous blood flow into the gill arches. The bulbus arteriosus has three distinct layers. Hu et al. 2000.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000173", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0004707 name: pharyngula stage namespace: uberon def: "A stage that follows the blastula, gastrula and neurula stages. At the pharyngula stage, all vertebrate embryos show remarkable similarities." [Wikipedia:Pharyngula] subset: efo_slim synonym: "pharyngula" RELATED [] synonym: "phylotypic stage" EXACT [] xref: DrerDO:0000052 xref: EFO:0001310 xref: OGES:000006 xref: Wikipedia:Pharyngula xref: ZFS:0000050 is_a: UBERON:0000105 ! life cycle stage relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000111 ! organogenesis stage relationship: preceded_by UBERON:0000110 ! neurula stage property_value: UBPROP:0000008 "Corresponds to E7-E11 in Mouse (Galis et al, TREE, 2001)" xsd:string [Term] id: UBERON:0004708 name: paired limb/fin namespace: uberon alt_id: UBERON:0009872 def: "An appendage that is part of an appendage girdle complex." [https://github.com/geneontology/go-ontology/issues/9029, UBERON:cjm] subset: homology_grouping synonym: "girdle-associated appendage" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "jointed paired lateral appendage" NARROW [https://orcid.org/0000-0002-6601-2165] synonym: "limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "paired appendage" NARROW [VSAO:0000067] synonym: "pectoral or pelvic appendage" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pelvic/pectoral appendage" EXACT [https://orcid.org/0000-0002-6601-2165] xref: VSAO:0000067 is_a: CARO:0000003 ! connected anatomical structure is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000026 {source="VSAO"} ! appendage intersection_of: UBERON:0000026 ! appendage intersection_of: part_of UBERON:0010707 ! appendage girdle complex relationship: connected_to UBERON:0007823 ! appendage girdle region relationship: develops_from UBERON:0004357 {evidence="definitional"} ! paired limb/fin bud relationship: has_part UBERON:0000014 ! zone of skin relationship: has_part UBERON:0001015 ! musculature relationship: has_part UBERON:0002049 ! vasculature relationship: has_skeleton UBERON:0011582 ! paired limb/fin skeleton relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0010707 {source="VSAO"} ! appendage girdle complex property_value: IAO:0000232 "this class is the union of the classes limb, pectoral fin and pelvic fin." xsd:string [Term] id: UBERON:0004709 name: pelvic appendage namespace: uberon alt_id: UBERON:0009876 def: "Paired appendage that consists of the posterior appendicular skeleton and associated soft and hard tissues, but excludes the pelvic girdle and its associated soft and hard tissues." [VSAO:0000150] subset: homology_grouping synonym: "hindlimb/pelvic fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pelvic appendage" EXACT [VSAO:0000126] synonym: "pelvic limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "posterior appendage" BROAD [] synonym: "posterior limb/fin" EXACT [] synonym: "posterior paired appendage" EXACT [VSAO:0000126] xref: VSAO:0000126 is_a: UBERON:0004708 ! paired limb/fin intersection_of: UBERON:0004708 ! paired limb/fin intersection_of: part_of UBERON:0010709 ! pelvic complex disjoint_from: UBERON:0004710 {source="lexical"} ! pectoral appendage relationship: connected_to UBERON:0001271 ! pelvic girdle region relationship: develops_from UBERON:0005420 {evidence="definitional"} ! pelvic appendage bud relationship: has_skeleton UBERON:0007273 ! pelvic appendage skeleton relationship: part_of UBERON:0010709 ! pelvic complex [Term] id: UBERON:0004710 name: pectoral appendage namespace: uberon alt_id: UBERON:0009875 def: "Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues." [VSAO:0000150-modified] subset: homology_grouping synonym: "anterior appendage" BROAD [] synonym: "anterior limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "anterior paired appendage" EXACT [VSAO:0000148] synonym: "forelimb - pectoral fin" EXACT [VHOG:0001753] synonym: "forelimb or pectoral fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "forelimb/pectoral fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pectoral limb/fin" EXACT [https://orcid.org/0000-0002-6601-2165] xref: VHOG:0001753 xref: VSAO:0000125 is_a: UBERON:0004708 ! paired limb/fin intersection_of: UBERON:0004708 ! paired limb/fin intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: connected_to UBERON:0001421 ! pectoral girdle region relationship: develops_from UBERON:0005419 {evidence="definitional"} ! pectoral appendage bud relationship: has_skeleton UBERON:0007272 ! pectoral appendage skeleton relationship: part_of UBERON:0010708 ! pectoral complex property_value: UBPROP:0000003 "While the skeletons of teleost pectoral fins and tetrapod forelimbs are homologous at the level of endoskeletal radials, teleosts and tetrapods do not share homologous skeletal elements at the level of 'individuated' pro-, meso-, and metapterygia. Among osteichthyans, only basal actinopterygians retain the full complement of elements present in non-osteichthyan gnathostomes.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001753", ontology="VHOG", source="DOI:10.1002/jmor.10264 Davis MC, Shubin NH, Force A, Pectoral fin and girdle development in the basal actinopterygians Polyodon spathula and Acipenser transmontanus. Journal of Morphology (2004)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004711 name: jugular vein namespace: uberon def: "The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava." [Wikipedia:Jugular_vein] synonym: "jugular" RELATED [] synonym: "vena jugularis" RELATED [BTO:0001744] xref: BTO:0001744 xref: CALOHA:TS-0497 xref: EMAPA:18638 xref: GAID:536 xref: MA:0002154 xref: MESH:D007601 xref: NCIT:C12738 xref: SCTID:244403000 xref: UMLS:C0022427 {source="ncithesaurus:Jugular_Vein"} xref: Wikipedia:Jugular_vein is_a: UBERON:0001638 ! vein relationship: drains UBERON:0000033 ! head relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000974 {gci_filler="NCBITaxon:40674", gci_relation="in_taxon"} ! neck property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray558.png" xsd:anyURI [Term] id: UBERON:0004716 name: conceptus namespace: uberon def: "The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]." [BTO:0003834, Wikipedia:Conceptus] synonym: "embryo plus adnexa" EXACT [] xref: AEO:0000194 xref: BTO:0003834 xref: EHDAA2:0000001 xref: EHDAA2:0003235 xref: EMAPA:36040 xref: NCIT:C34131 xref: UMLS:C1516779 {source="ncithesaurus:Conceptus"} xref: Wikipedia:Conceptus is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 ! anatomical structure relationship: develops_from CL:0000365 ! animal zygote relationship: existence_ends_with UBERON:0000068 ! embryo stage relationship: existence_starts_with UBERON:0000068 ! embryo stage relationship: has_part UBERON:0002050 ! embryonic structure relationship: has_part UBERON:0016887 ! entire extraembryonic component property_value: editor_note "EHDAA2 places this as a subtype of organism. This leads to the inference that a conceptus is an embryo (if an embryo is defined as an organism at embryo stage), which eliminates the embryonic + extra-embryonic = conceptus" xsd:string [Term] id: UBERON:0004729 name: nematode larval stage namespace: uberon def: "Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." [GO:0002119] xref: WBls:0000023 is_a: UBERON:0000069 ! larval stage relationship: only_in_taxon NCBITaxon:6231 ! Nematoda relationship: simultaneous_with GO:0002119 ! nematode larval development property_value: seeAlso "https://github.com/obophenotype/uberon/issues/567" xsd:anyURI [Term] id: UBERON:0004731 name: neuromere namespace: uberon def: "A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres)." [DOI:10.1016/j.tins.2013.06.004, https://github.com/obophenotype/uberon/issues/318] subset: pheno_slim synonym: "neural metamere" RELATED [] synonym: "neural segment" RELATED [] synonym: "neural tube metameric segment" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "neural tube segment" EXACT [] synonym: "neuromere" EXACT [] synonym: "neuromeres" EXACT PLURAL [TAO:0001328] xref: NLX:147842 xref: TAO:0001328 xref: Wikipedia:Neuromere xref: ZFA:0001328 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004732 ! segmental subdivision of nervous system intersection_of: UBERON:0004732 ! segmental subdivision of nervous system intersection_of: part_of UBERON:0001049 ! neural tube relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: part_of UBERON:0001049 ! neural tube property_value: editor_note "We take the definition of neuromere from Puelles et al, although the existence of mesomeres and prosomeres may not be widely accepted" xsd:string property_value: UBPROP:0000001 "A metameric segment of the central nervous system.[ZFA]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001328", ontology="TAO", source="ZFIN:curator"} creation_date: 2009-06-18T09:00:04Z [Term] id: UBERON:0004732 name: segmental subdivision of nervous system namespace: uberon def: "Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres." [FBbt:00005140, http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "neuromere" RELATED [FBbt:00005140] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000063 ! organ subunit intersection_of: UBERON:0000063 ! organ subunit intersection_of: part_of UBERON:0001016 ! nervous system relationship: part_of UBERON:0001016 ! nervous system property_value: editor_note "revisit this after CARO is revised and/or we have defined metameric segment; note that with the additional of an A/P axis constraint this corresponds to what Richter at al call a neuromere (PMID:21062451)" xsd:string [Term] id: UBERON:0004733 name: segmental subdivision of hindbrain namespace: uberon def: "An organ subunit that is part of a hindbrain [Automatically generated definition]." [OBOL:automatic] subset: non_informative synonym: "hindbrain segment" EXACT [FMA:61998] synonym: "segment of hindbrain" EXACT [FMA:61998] xref: FMA:61998 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004732 ! segmental subdivision of nervous system intersection_of: UBERON:0000063 ! organ subunit intersection_of: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0004734 name: gastrula namespace: uberon alt_id: UBERON:0007012 def: "Organism at the gastrula stage." [Wikipedia:Gastrula, Wikipedia:Trilaminar_blastocyst] subset: pheno_slim synonym: "blastocystis trilaminaris" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "gastrula embryo" EXACT [BILA:0000060] synonym: "tri-laminar disc" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "tri-laminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastocyst" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar blastoderm" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar disc" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar disk" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "trilaminar germ" RELATED [https://orcid.org/0000-0002-6601-2165] xref: BILA:0000060 xref: BTO:0001403 xref: FBbt:00005317 xref: FMA:293108 xref: GAID:1302 xref: MESH:D005775 xref: MIAA:0000179 xref: NCIT:C34057 xref: NCIT:C34058 xref: UMLS:C0017199 {source="ncithesaurus:Gastrula"} xref: UMLS:C1284022 {source="ncithesaurus:Trilaminar_Embryonic_Disc"} xref: Wikipedia:Gastrula xref: Wikipedia:Trilaminar_blastocyst is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_and_ends_during UBERON:0000109 ! gastrula stage relationship: develops_from UBERON:0000307 ! blastula relationship: existence_starts_and_ends_during UBERON:0000109 ! gastrula stage property_value: UBPROP:0000012 "We explicitly merge the NCITA terms here" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0004737 name: metanephric collecting duct namespace: uberon def: "A collecting duct of renal tubule that is part of a metanephros [Automatically generated definition]." [OBOL:automatic] synonym: "collecting duct of metanephros" EXACT [] synonym: "metanephric collecting tubule" RELATED [VHOG:0000983] xref: VHOG:0000983 is_a: UBERON:0001232 ! collecting duct of renal tubule is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001232 ! collecting duct of renal tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0003220 {source="Wikipedia-abduced"} ! metanephric mesenchyme relationship: develops_from UBERON:0014706 ! primitive renal collecting duct system relationship: part_of UBERON:0005110 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron [Term] id: UBERON:0004742 name: dentary namespace: uberon def: "The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians, extending to the whole lower jaw in mammals[VHOG,modified]." [VHOG:0001022] subset: efo_slim synonym: "dentale" RELATED [AAO:0000124] synonym: "dentaries" EXACT PLURAL [TAO:0000191] synonym: "dentary bone" EXACT [ZFA:0000191] synonym: "os dentale" RELATED [AAO:0000124] synonym: "sur-angulaire" RELATED [AAO:0000124] xref: AAO:0000124 xref: EFO:0003508 xref: http://palaeos.com/vertebrates/bones/dermal/images/Dentary1.gif xref: TAO:0000191 xref: VHOG:0001022 xref: ZFA:0000191 is_a: UBERON:0004768 ! bone of lower jaw is_a: UBERON:0008907 {source="ZFA"} ! dermal bone is_a: UBERON:0015212 ! lateral structure relationship: develops_from UBERON:0010336 {source="EHDAA2"} ! mandibular process mesenchyme from neural crest relationship: has_developmental_contribution_from UBERON:0003324 {source="EHDAA2-modified"} ! mesenchyme of lower jaw relationship: in_lateral_side_of UBERON:0003278 ! skeleton of lower jaw relationship: part_of UBERON:0003113 {notes="mandibular series", source="ISBN:0073040584", source="ZFA"} ! dermatocranium property_value: UBPROP:0000001 "Dermal bone that is usually the anteriormost bone of the lower jaw, and that articulates with the angular, or anguloarticular bone, posteriorly, and carries part of the mandibular sensory canal and pore openings of the mandibular sensory canal on its lateral surface. The dentary is a paired bone.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000191", ontology="TAO", source="TAO:GA_TG"} property_value: UBPROP:0000001 "Ossified element of intramembranous origin that invests the lateral margin of Meckel's cartilage thereby forming the lateral side of the mandible in anurans and salamanders (Duellman & Trueb, 1994:293). In caecilians, the dentary is part of a compound bone termed the pseudodentary.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000124", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians. In mammals the lower jaw consists entirely of the dentary bone. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Grande_L, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF, ZFA:0000191_and_Liem_KF, p.248][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001022", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000002 "relationship loss: overlaps dentary-anguloarticular joint (TAO:0001749)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000191", ontology="TAO"} property_value: UBPROP:0000003 "Of all these bones [dentary, splenials, coronoids, angular, surangular and prearticular], only the dentary remains in the lower jaw of a mammal.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001022", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.248", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In lobe-finned fishes and the early fossil tetrapods, the bone homologous to the mandible of mammals is merely the largest of several bones in the lower jaw. In such animals, it is referred to as the dentary bone, and forms the body of the outer surface of the jaw. It is bordered below by a number of splenial bones, while the angle of the jaw is formed by a lower angular bone and a suprangular bone just above it. The inner surface of the jaw is lined by a prearticular bone, while the articular bone forms the articulation with the skull proper. Finally a set of three narrow coronoid bones lie above the prearticular bone. As the name implies, the majority of the teeth are attached to the dentary, but there are commonly also teeth on the coronoid bones, and sometimes on the prearticular as well. This complex primitive pattern has, however, been simplified to various degrees in the great majority of vertebrates, as bones have either fused or vanished entirely. In teleosts, only the dentary, articular, and angular bones remain, while in living amphibians, the dentary is accompanied only by the prearticular, and, in salamanders, one of the coronoids. The lower jaw of reptiles has only a single coronoid and splenial, but retains all the other primitive bones except the prearticular." xsd:string [Term] id: UBERON:0004747 name: supraoccipital bone namespace: uberon alt_id: UBERON:0005237 def: "Endochondral bone that is located at the dorsal part of the occipital region of the cranium or the dorso-posterior part of the skull[TAP,modified]." [TAO:0000595] subset: pheno_slim subset: vertebrate_core synonym: "supraoccipital" EXACT [VHOG:0001150] xref: EMAPA:36618 xref: MA:0001474 xref: SCTID:95947006 xref: TAO:0000595 xref: VHOG:0001150 xref: ZFA:0000595 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0011164 ! neurocranium bone is_a: UBERON:0015015 ! supraoccipital endochondral element intersection_of: UBERON:0015015 ! supraoccipital endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0011162 ! supraoccipital cartilage element relationship: part_of UBERON:0001676 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="ISBN:0073040584"} ! occipital bone property_value: UBPROP:0000001 "a bone on the dorsal side of the great foramen of the skull, usually forming a part of the occipital in the adult, but distinct in the young..[TFD]" xsd:string {date_retrieved="2012-09-06", source="http://www.thefreedictionary.com/Supraoccipital"} property_value: UBPROP:0000001 "Endochondral bone that is located at the dorsal part of the occipital region of the cranium or the dorso-posterior part of the skull. It forms the dorsal margin of the foramen magnum. Commonly the supraoccipital articulates with the parietals anteriorly, the epiotics laterally, and the exoccipitals posteroventrally. The supraoccipital is an unpaired median bone.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000595", ontology="TAO", source="TAO:GA_TG"} property_value: UBPROP:0000001 "The supraoccipital ties the occiput to the dermal skull table.[Palaeos]" xsd:string {date_retrieved="2012-09-06", source="http://palaeos.com/vertebrates/bones/braincase/occiput.html"} property_value: UBPROP:0000002 "relationship loss: overlaps supraoccipital-parietal joint (TAO:0005264)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000595", ontology="TAO"} property_value: UBPROP:0000002 "relationship type change: overlaps neurocranium (TAO:0001580) CHANGED TO: part_of neurocranium (UBERON:0001703)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000595", ontology="TAO"} property_value: UBPROP:0000008 "See Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution, Fourth Edition (2006) McGraw-Hill, p.237 Table 7.1; usually forming a part of the occipital in the adult, but distinct in the young" xsd:string {source="PMID:10742104"} [Term] id: UBERON:0004753 name: scapulocoracoid namespace: uberon def: "Skeletal element that consists of the scapula and the coracoid[VSAO, modified]." [https://github.com/obophenotype/uberon/issues/125, https://github.com/obophenotype/uberon/issues/66, VSAO:0005002, Wikipedia:Scapulocoracoid] synonym: "coraco-scapular cartilage" NARROW [ZFA:0001455] synonym: "scapulo-coracoid cartilage" NARROW [TAO:0001455] synonym: "scapulocoracoid cartilage" NARROW [TAO:0001455] synonym: "scapulocoracoideum" EXACT [VSAO:0005002] xref: AAO:0000781 xref: TAO:0001455 xref: VSAO:0005002 xref: Wikipedia:Scapulocoracoid xref: ZFA:0001455 is_a: UBERON:0004765 ! skeletal element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0007831 {source="VSAO"} ! pectoral girdle skeleton property_value: editor_note "todo - decide whether to create separate classes for cartilage & ossified. Wikipedia considers this absent in Therians, but if considered as a grouping of scapula and coracoid then it would be present" xsd:string property_value: UBPROP:0000001 "either a fusion of the scapula and coracoid (the two main bones of the shoulder girdle), or the scapula & coracoid considered as a single structural unit.[Palaeos]" xsd:string {date_retrieved="2012-09-10", source="http://palaeos.com/vertebrates/glossary/glossaryS.html"} property_value: UBPROP:0000001 "Fused, ossified portions of the scapula, procoracoid, and coracoid.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000781", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "Pectoral fin cartilage that consists of a paired cartilaginous plate of the embryonic primary pectoral girdle and from which the scapular and coracaoid bones ossify.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001455", ontology="TAO", source="TAO:GA_TG", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: part_of scapular area (AAO:0000935)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000781", ontology="AAO"} property_value: UBPROP:0000012 "ZFA defines as precursor to scapula and coracoid. Cartilage in TAO" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0004755 name: skeletal tissue namespace: uberon def: "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/134, PSPUB:0000170, VSAO:0000015] comment: Four classes of mineralized tissues are found in vertebrates: bone, cartilage, dentine, and enamel. We think of cartilage and bone as skeletal tissues and of enamel and dentine as dental tissues, but enamel and dentine arose evolutionarily together with bone as skeletal tissues in the dermal skeleton (exoskeleton) of early vertebrates. Scales and teeth of sharks are examples of dermal skeletal elements that are still composed of the three ancient components-enamel, dentine, and bone. Cartilage, on the other hand, provided the basis for the second vertebrate skeletal system, the endoskeleton (Smith and Hall, 1990; Hall, 1998a,b). some invertebrate skeletal tissues have surprisingly bone-like features. Examples include chondrocytes interconnected by cell processes in cephalopod cartilages (Cole and Hall, 2004a,b), and the calcium phosphate layer in the shells of brachiopods (Rodland et al., 2003). However, neither bone nor mineralized cartilage have been found in invertebrates. Editors notes: TODO - develops_from xref: EMAPA:37744 {source="MA:th"} xref: MA:0003047 xref: SCTID:309311006 xref: VSAO:0000015 xref: XAO:0004038 xref: ZFA:0005619 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002384 {source="VSAO"} ! connective tissue relationship: develops_from CL:0007001 {date_retrieved="2012-08-14", external_class="VSAO:0000015", source="VSAO"} ! skeletogenic cell relationship: part_of UBERON:0004765 ! skeletal element property_value: UBPROP:0000001 "A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000015", notes="taken from version of VSAO used in TAO and used directly in Uberon", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} [Term] id: UBERON:0004756 name: dermal skeletal element namespace: uberon def: "Dermis-derived entity that is made of skeletal tissue." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/206] synonym: "dermal element" EXACT [VSAO:curator] is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004765 ! skeletal element intersection_of: UBERON:0004765 ! skeletal element intersection_of: develops_from UBERON:0002067 ! dermis intersection_of: has_part UBERON:0004755 ! skeletal tissue relationship: develops_from UBERON:0002067 ! dermis relationship: has_part UBERON:0004755 ! skeletal tissue [Term] id: UBERON:0004760 name: gland of anal canal namespace: uberon def: "A gland that is part of an anal canal [Automatically generated definition]." [OBOL:automatic, Wikipedia:Anal_gland] subset: human_reference_atlas subset: organ_slim synonym: "anal gland" RELATED [] synonym: "anal sac" RELATED SENSU [Wikipedia:Anal_gland] synonym: "gland of anal canal" EXACT [OBOL:automatic] synonym: "gland of anus" RELATED [] synonym: "rectal gland" RELATED [] xref: EMAPA:27221 xref: EMAPA:27233 xref: EMAPA:27543 xref: FMA:15720 xref: FMA:15724 xref: NCIT:C32068 xref: SCTID:245448005 xref: UMLS:C0162322 {source="ncithesaurus:Anal_Gland"} xref: Wikipedia:Anal_gland is_a: UBERON:0003408 ! gland of digestive tract is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000159 ! anal canal relationship: part_of UBERON:0000159 ! anal canal property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004761 name: cartilaginous neurocranium namespace: uberon def: "The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]." [Wikipedia:Chondrocranium] synonym: "cartilaginous chondocranium" EXACT [] synonym: "cartilaginous skull" RELATED [] synonym: "cartiligionous skeletal structure of skull" EXACT [] synonym: "chondocranium" RELATED [Wikipedia:Chondrocranium] synonym: "embryonic chondocranium" RELATED [] synonym: "neurocranium" RELATED SENSU [] xref: AAO:0000094 xref: AAO:0010153 xref: EHDAA:6031 xref: FMA:76621 xref: NCIT:C34121 xref: SCTID:155540009 xref: UMLS:C1516496 {source="ncithesaurus:Chondrocranium"} xref: Wikipedia:Chondrocranium xref: XAO:0003059 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: develops_from UBERON:0009617 {source="PMC1571569"} ! head paraxial mesoderm relationship: has_part UBERON:0002418 ! cartilage tissue relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: UBPROP:0000012 "in contrast to chondrocranium, this structure is entirely cartiliginous. In Chondricthyes this is the same as the neurocranium. FMA:76621 is an undefined fetal structure, so we assume the correct placement is here. Note that this is distinct from MA:0000317 which is the uberon:neurocranium (the part of the cranium that encloses the brain)" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004764 name: intramembranous bone tissue namespace: uberon def: "Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]." [GO:0001957, Wikipedia:Intramembranous_ossification] xref: MA:0002837 xref: Wikipedia:Intramembranous_ossification is_a: UBERON:0002481 ! bone tissue intersection_of: UBERON:0002481 ! bone tissue intersection_of: output_of GO:0001957 ! intramembranous ossification relationship: develops_from UBERON:0003104 ! mesenchyme relationship: output_of GO:0001957 ! intramembranous ossification relationship: part_of UBERON:0002514 ! intramembranous bone property_value: UBPROP:0000012 "note the distinction between intramembranous bone and intramembranous bone tissue. Some bones may be a mixture of both tissue types. The MA class most likely refers to a tissue type (it is under bone tissue and connective tissue; there are no child classes)" xsd:string {external_ontology="MA"} [Term] id: UBERON:0004765 name: skeletal element namespace: uberon def: "Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles." [https://orcid.org/0000-0002-6601-2165] subset: organ_slim subset: uberon_slim xref: AAO:0011129 xref: galen:SkeletalStructure xref: TAO:0001890 xref: VSAO:0000128 xref: XAO:0004012 xref: ZFA:0005494 is_a: UBERON:0000062 ! organ relationship: part_of UBERON:0001434 {source="VSAO"} ! skeletal system property_value: UBPROP:0000001 "Organ entity that is typically involved in mechanical support and may have different skeletal tissue compositions at different stages.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000128", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Organ entity that may have different tissue compositions at different stages and is typically involved in mechanical support.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001890", ontology="TAO", source="TAO:VSAO_workshop"} [Term] id: UBERON:0004766 name: cranial bone namespace: uberon def: "A bone that is part of a cranium." [UBERON:automatic] subset: human_reference_atlas synonym: "cranium bone" EXACT [UBERON:automatic] xref: SCTID:181792001 is_a: UBERON:0003457 ! head bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0003128 ! cranium relationship: part_of UBERON:0003128 ! cranium property_value: IAO:0000232 "here cranium = skull - mandible" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004767 name: vomerine tooth namespace: uberon def: "A tooth that is on the vomer." [http://www.encyclo.co.uk/define/Vomerine%20teeth] xref: AAO:0000635 xref: TAO:0001631 is_a: UBERON:0012070 ! palatal tooth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0002396 ! vomer relationship: attaches_to UBERON:0002396 ! vomer relationship: part_of UBERON:0017615 ! vomerine dentition property_value: UBPROP:0000001 "Tooth that is attached to the vomer.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001631", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000002 "relationship type change: OBO_REL:part_of vomer (TAO:0000308) CHANGED TO: attaches_to vomer (UBERON:0002396)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001631", ontology="TAO"} [Term] id: UBERON:0004768 name: bone of lower jaw namespace: uberon def: "Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "lower jaw bone" EXACT [] is_a: UBERON:0012360 ! bone of jaw intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: part_of UBERON:0003278 ! skeleton of lower jaw property_value: editor_note "Do not manually classify under here - bones are automatically classified" xsd:string [Term] id: UBERON:0004769 name: diaphysis namespace: uberon def: "Subdivision of long bone which forms the part of the bone between the two epiphyses, excluding the metaphyses[FMA,modified]." [FMA:24013, Wikipedia:Diaphysis] subset: pheno_slim subset: uberon_slim synonym: "body of long bone" EXACT [] synonym: "long bone diaphysis" EXACT [] synonym: "shaft of long bone" EXACT [] xref: EMAPA:35504 xref: FMA:24013 xref: GAID:189 xref: MESH:D018483 xref: SCTID:361729006 xref: Wikipedia:Diaphysis is_a: UBERON:0005055 ! zone of long bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/94/Illu_long_bone.jpg" xsd:anyURI property_value: UBPROP:0000001 "Subdivision of long bone which forms the part of the bone between the two epiphyses; together with other the subdivisions of long bone, it constitutes the long bone. Examples: diaphysis of humerus, diaphysis of femur[FMA]." xsd:string {source="FMA:24013"} property_value: UBPROP:0000001 "The main or mid section (shaft) of a long bone. It is made up of cortical bone and usually contains bone marrow and adipose tissue (fat)[WP][FMA:24013, Wikipedia:Diaphysis]." xsd:string {source="FMA:24013, Wikipedia:Diaphysis"} [Term] id: UBERON:0004770 name: articular system namespace: uberon def: "Anatomical system that consists of all the joints of the body." [VSAO:0000181] synonym: "joint system" EXACT [FMA:23878] synonym: "set of all joints" RELATED [] synonym: "set of all joints of body" EXACT [FMA:23878] synonym: "set of joints of body" RELATED [FMA:23878] xref: EMAPA:35150 xref: FMA:23878 xref: MA:0003007 xref: SCTID:361827000 xref: VSAO:0000181 is_a: UBERON:0034925 ! anatomical collection intersection_of: UBERON:0034925 ! anatomical collection intersection_of: has_member UBERON:0000982 ! skeletal joint relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: functionally_related_to GO:0040011 ! locomotion relationship: has_member UBERON:0000982 ! skeletal joint relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0001434 {source="FMA"} ! skeletal system [Term] id: UBERON:0004771 name: posterior nasal aperture namespace: uberon def: "Opening/conduit between the nasal cavity and the nasopharynx[AAO] The choanae are separated by the vomer[WP]." [AAO:0000093, Wikipedia:Posterior_nasal_apertures] subset: pheno_slim synonym: "choana" BROAD [Wikipedia:Choane, XAO:0000277] synonym: "choanae" RELATED PLURAL [VHOG:0000545] synonym: "internal naris" BROAD [MA:0001323] synonym: "nasopharyngeal naris" RELATED [] synonym: "posterior choana" RELATED [HP:0004496] synonym: "posterior naris" RELATED [VHOG:0000545] synonym: "posterior nasal apperture" EXACT [XAO:0000277] xref: AAO:0000093 xref: EHDAA2:0000242 xref: EHDAA:7842 xref: EMAPA:17849 xref: FMA:53143 xref: MA:0001323 xref: SCTID:244507001 xref: VHOG:0000545 xref: Wikipedia:Posterior_nasal_apertures xref: XAO:0000277 is_a: UBERON:0010425 ! internal naris is_a: UBERON:0036253 ! orifice of skull intersection_of: UBERON:0010425 ! internal naris intersection_of: connects UBERON:0001707 ! nasal cavity intersection_of: connects UBERON:0001728 ! nasopharynx relationship: connects UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0003128 ! cranium property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/87/Gray855.png" xsd:anyURI property_value: UBPROP:0000001 "One of the paired openings from the nasal cavities into the pharynx. [Bemis_WE, Functional_Anatomy_of_the_Vertebrates:_An_Evolutionary_Perspective, Glossary_G-6, Grande_L, Liem_KF, Third_Edition_(2001)_Orlando_Fla.:_Harcourt_College_Publishers, Walker_WF][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000545", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Opening between the nasal cavity and the nasopharynx.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000093", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "The choana, a unique 'internal nostril' opening from the nasal sac into the roof of the mouth, is a key part of the tetrapod (land vertebrate) respiratory system. It was the first component of the tetrapod body plan to evolve, well before the origin of limbs, and is therefore crucial to our understanding of the beginning of the fish-tetrapod transition. (...) Here we present new material of Kenichthys, a 395-million-year-old fossil fish from China, that provides direct evidence for the origin of the choana and establishes its homology: it is indeed a displaced posterior external nostril that, during a brief transitional stage illustrated by Kenichthys, separated the maxilla from the premaxilla.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000545", ontology="VHOG", source="DOI:10.1038/nature02843 Zhu M, Ahlberg PE, The origin of the internal nostril in tetrapodes. Nature (2004)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Fish don't have choanae, instead they have two pairs of external nostrils" xsd:string {source="WP"} property_value: UBPROP:0000008 "In addition to tetrapods, the lungfish has internal nostrils too. In tetrapods the exhalant nostril (choana) empties into the buccal cavity." xsd:string [Term] id: UBERON:0004777 name: respiratory system submucosa namespace: uberon def: "A submucosa that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius submucosa" EXACT [OBOL:automatic] synonym: "submucosa of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "submucosa of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37578 {source="MA:th"} xref: MA:0001822 is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003570 ! respiratory system connective tissue [Term] id: UBERON:0004778 name: larynx submucosa namespace: uberon def: "A submucosa that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "laryngeal submucosa" RELATED [EMAPA:35474] synonym: "submucosa of larynx" EXACT [OBOL:automatic] xref: EMAPA:35474 xref: FMA:321584 xref: MA:0002728 xref: SCTID:361941005 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004777 ! respiratory system submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001737 ! larynx [Term] id: UBERON:0004779 name: respiratory system lamina propria namespace: uberon def: "A lamina propria that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "apparatus respiratorius lamina propria" EXACT [OBOL:automatic] synonym: "apparatus respiratorius lamina propria mucosa" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of respiratory system" EXACT [OBOL:automatic] synonym: "lamina propria of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "lamina propria of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system lamina propria mucosa" EXACT [OBOL:automatic] xref: EMAPA:37576 {source="MA:th"} xref: MA:0001821 is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003570 ! respiratory system connective tissue relationship: part_of UBERON:0004785 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system mucosa [Term] id: UBERON:0004780 name: gastrointestinal system lamina propria namespace: uberon def: "A lamina propria that is part of a gastrointestinal system." [OBOL:automatic] xref: MA:0001899 xref: NCIT:C49299 xref: UMLS:C1708197 {source="ncithesaurus:Gastrointestinal_Tract_Lamina_Propria"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system relationship: part_of UBERON:0004786 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! gastrointestinal system mucosa [Term] id: UBERON:0004781 name: gallbladder lamina propria namespace: uberon def: "A lamina propria that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "biliary lamina propria" RELATED [MA:0001633] synonym: "gall bladder lamina propria" EXACT [OBOL:automatic] synonym: "gall bladder lamina propria mucosa" EXACT [OBOL:automatic] synonym: "gallbladder lamina propria mucosa" EXACT [] synonym: "lamina propria mucosa of gall bladder" EXACT [OBOL:automatic] synonym: "lamina propria mucosa of gallbladder" EXACT [OBOL:automatic] synonym: "lamina propria of gall bladder" EXACT [OBOL:automatic] synonym: "lamina propria of gallbladder" EXACT [OBOL:automatic] xref: EMAPA:35371 xref: FMA:278594 xref: MA:0001633 xref: NCIT:C49228 xref: UMLS:C1708175 {source="ncithesaurus:Gallbladder_Lamina_Propria"} is_a: UBERON:0000030 ! lamina propria is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0005033 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mucosa of gallbladder [Term] id: UBERON:0004782 name: gastrointestinal system serosa namespace: uberon def: "A serous membrane that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "digestive system serosa" EXACT [OBOL:automatic] synonym: "digestive system serous membrane" EXACT [OBOL:automatic] synonym: "gastrointestinal system serous membrane" EXACT [OBOL:automatic] synonym: "serosa of digestive system" EXACT [OBOL:automatic] synonym: "serosa of gastrointestinal system" EXACT [OBOL:automatic] synonym: "serous membrane of digestive system" EXACT [OBOL:automatic] synonym: "serous membrane of gastrointestinal system" EXACT [OBOL:automatic] xref: EMAPA:37592 {source="MA:th"} xref: MA:0001522 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system [Term] id: UBERON:0004783 name: gallbladder serosa namespace: uberon def: "A serous membrane that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "biliary serosa" RELATED [MA:0001634] synonym: "gall bladder serosa" EXACT [OBOL:automatic] synonym: "gall bladder serous membrane" EXACT [] synonym: "gallbladder serous membrane" EXACT [OBOL:automatic] synonym: "serosa of gall bladder" EXACT [OBOL:automatic] synonym: "serosa of gallbladder" EXACT [OBOL:automatic] synonym: "serous coat of gallbladder" EXACT [FMA:14659] synonym: "serous membrane of gall bladder" EXACT [OBOL:automatic] synonym: "serous membrane of gallbladder" EXACT [OBOL:automatic] synonym: "tunica serosa (vesica biliaris)" EXACT [FMA:14659] synonym: "tunica serosa vesicae biliaris" EXACT LATIN [FMA:14659, FMA:TA] xref: EMAPA:35372 xref: FMA:14659 xref: MA:0001634 xref: SCTID:362197006 is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: UBERON:0004784 name: heart ventricle wall namespace: uberon def: "An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "anatomical wall of cardiac ventricle" EXACT [OBOL:automatic] synonym: "anatomical wall of heart ventricle" EXACT [OBOL:automatic] synonym: "anatomical wall of lower chamber of heart" EXACT [OBOL:automatic] synonym: "anatomical wall of ventricle of heart" EXACT [OBOL:automatic] synonym: "cardiac ventricle anatomical wall" EXACT [OBOL:automatic] synonym: "cardiac ventricle wall" EXACT [OBOL:automatic] synonym: "heart ventricle anatomical wall" EXACT [OBOL:automatic] synonym: "lower chamber of heart anatomical wall" EXACT [OBOL:automatic] synonym: "lower chamber of heart wall" EXACT [OBOL:automatic] synonym: "ventricle of heart anatomical wall" EXACT [OBOL:automatic] synonym: "ventricle of heart wall" EXACT [OBOL:automatic] synonym: "ventricular wall" EXACT [FMA:13884] synonym: "wall of cardiac ventricle" EXACT [OBOL:automatic] synonym: "wall of heart ventricle" EXACT [OBOL:automatic] synonym: "wall of lower chamber of heart" EXACT [OBOL:automatic] synonym: "wall of ventricle" RELATED [MA:0002791] synonym: "wall of ventricle of heart" EXACT [OBOL:automatic] xref: FMA:13884 xref: MA:0002791 xref: NCIT:C119295 is_a: UBERON:0037144 ! wall of heart intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle [Term] id: UBERON:0004785 name: respiratory system mucosa namespace: uberon def: "The mucous membrane lining the respiratory tract." [MESH:A04.760, MGI:cwg, MP:0002277] subset: pheno_slim synonym: "apparatus respiratorius mucosa" EXACT [OBOL:automatic] synonym: "apparatus respiratorius mucosa of organ" EXACT [OBOL:automatic] synonym: "apparatus respiratorius mucous membrane" EXACT [OBOL:automatic] synonym: "laryngeal mucous membrane" RELATED [EMAPA:18334] synonym: "mucosa of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "mucosa of organ of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "mucosa of organ of respiratory system" EXACT [OBOL:automatic] synonym: "mucosa of respiratory system" EXACT [OBOL:automatic] synonym: "mucous membrane of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "mucous membrane of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory mucosa" RELATED [BTO:0000973] synonym: "respiratory system mucosa of organ" EXACT [OBOL:automatic] synonym: "respiratory system mucous membrane" EXACT [OBOL:automatic] synonym: "respiratory tract mucosa" RELATED [] xref: BTO:0000973 xref: EMAPA:18334 xref: EMAPA:37577 {source="MA:th"} xref: FMA:302092 xref: GAID:304 xref: MA:0001827 xref: MESH:D020545 is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system property_value: editor_note "TODO - split respiratory tract mucosa from respiratory system mucosa" xsd:string [Term] id: UBERON:0004786 name: gastrointestinal system mucosa namespace: uberon def: "A mucosa that is part of a gastrointestinal system." [OBOL:automatic] comment: The gut mucosa of amphioxus has insulin-secreting cells. http://www.ncbi.nlm.nih.gov/pubmed/16417468 synonym: "digestive tract mucosa" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "gut mucosa" EXACT [BTO:0000546] synonym: "gut mucuous membrane" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "mucosa of gut" EXACT [https://orcid.org/0000-0002-6601-2165] xref: BTO:0000546 xref: BTO:0005568 xref: EMAPA:36591 xref: MA:0001521 xref: SCTID:410433007 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system relationship: adjacent_to UBERON:0006909 {source="BTO-modified"} ! lumen of digestive tract relationship: has_part CL:0000172 {source="PMID:16417468"} ! somatostatin secreting cell relationship: has_part CL:0000696 {source="PMID:16417468"} ! PP cell relationship: has_part CL:0002067 {source="PMID:16417468"} ! type A enteroendocrine cell relationship: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system [Term] id: UBERON:0004789 name: larynx mucous gland namespace: uberon def: "A mucous gland that is part of a larynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucous gland of larynx" EXACT [OBOL:automatic] xref: EMAPA:37631 {source="MA:th"} xref: MA:0001767 is_a: UBERON:0000414 ! mucous gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0000414 ! mucous gland intersection_of: part_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001824 ! mucosa of larynx [Term] id: UBERON:0004790 name: skin mucous gland namespace: uberon def: "A mucous gland that is part of the skin." [http://orcid.org/0000-0002-6601-2165] subset: organ_slim synonym: "mucous gland of entire skin" EXACT [OBOL:automatic] synonym: "mucous gland of skin of body" EXACT [OBOL:automatic] synonym: "skin mucus gland" EXACT [OBOL:automatic] synonym: "skin of body mucous gland" EXACT [OBOL:automatic] xref: EMAPA:35775 xref: MA:0000148 is_a: UBERON:0000414 ! mucous gland is_a: UBERON:0007771 ! epidermis gland is_a: UBERON:0019319 ! exocrine gland of integumental system intersection_of: UBERON:0000414 ! mucous gland intersection_of: part_of UBERON:0002097 ! skin of body property_value: editor_note "See comments for 'skin mucus'" xsd:string [Term] id: UBERON:0004792 name: secretion of endocrine pancreas namespace: uberon def: "A secretion that is part of a endocrine pancreas [Automatically generated definition]." [OBOL:automatic] synonym: "endocrine pancreas secretion" EXACT [OBOL:automatic] synonym: "pancreatic endocrine secretion" EXACT [ncithesaurus:Pancreatic_Endocrine_Secretion] synonym: "pars endocrina pancreatis secretion" EXACT [OBOL:automatic] synonym: "secretion of pars endocrina pancreatis" EXACT [OBOL:automatic] xref: MA:0002517 xref: NCIT:C33255 xref: UMLS:C1518866 {source="ncithesaurus:Pancreatic_Endocrine_Secretion"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004795 ! pancreas secretion intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: part_of UBERON:0000016 ! endocrine pancreas relationship: part_of UBERON:0000016 ! endocrine pancreas [Term] id: UBERON:0004793 name: secretion of exocrine pancreas namespace: uberon def: "A secretion that is part of a exocrine pancreas [Automatically generated definition]." [OBOL:automatic] synonym: "exocrine pancreas secretion" EXACT [OBOL:automatic] synonym: "pancreatic exocrine secretion" EXACT [ncithesaurus:Pancreatic_Exocrine_Secretion] synonym: "pars exocrina pancreatis secretion" EXACT [OBOL:automatic] synonym: "secretion of pars exocrina pancreatis" EXACT [OBOL:automatic] xref: MA:0002518 xref: NCIT:C33256 xref: UMLS:C1518867 {source="ncithesaurus:Pancreatic_Exocrine_Secretion"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004795 ! pancreas secretion intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0000017 ! exocrine pancreas [Term] id: UBERON:0004794 name: esophagus secretion namespace: uberon def: "A secretion that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] synonym: "esophageal secretion" EXACT [FMA:79662] synonym: "gullet secretion" EXACT [OBOL:automatic] synonym: "oesophagus secretion" EXACT [OBOL:automatic] synonym: "secretion of esophagus" EXACT [OBOL:automatic] synonym: "secretion of gullet" EXACT [OBOL:automatic] synonym: "secretion of oesophagus" EXACT [OBOL:automatic] xref: FMA:79662 xref: MA:0002514 xref: NCIT:C52555 xref: UMLS:C0227179 {source="ncithesaurus:Esophagus_Secretion"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0004795 name: pancreas secretion namespace: uberon def: "A secretion that is part of a pancreas [Automatically generated definition]." [OBOL:automatic] synonym: "pancreatic secretion" EXACT [OBOL:automatic] synonym: "secretion of pancreas" EXACT [OBOL:automatic] xref: MA:0002516 xref: NCIT:C13270 xref: UMLS:C0030296 {source="ncithesaurus:Pancreatic_Secretion"} is_a: UBERON:0000456 ! secretion of exocrine gland intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0001264 ! pancreas [Term] id: UBERON:0004797 name: blood vessel layer namespace: uberon def: "Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:36296 xref: MA:0002854 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: part_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0035965 ! wall of blood vessel property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/61/Blood_vessels.svg" xsd:anyURI [Term] id: UBERON:0004802 name: respiratory tract epithelium namespace: uberon def: "The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi." [ISBN:0-683-40008-8, MGI:anna, MP:0010942] subset: pheno_slim synonym: "airway epithelium" RELATED [BTO:0000419] synonym: "epithelial tissue of respiratory tract" EXACT [OBOL:automatic] synonym: "epithelium of respiratory tract" EXACT [OBOL:automatic] synonym: "respiratory epithelium" RELATED [BTO:0000419] synonym: "respiratory tract epithelial tissue" EXACT [OBOL:automatic] xref: BTO:0000419 xref: CALOHA:TS-0023 xref: EMAPA:32827 xref: MA:0001480 xref: SCTID:321764001 xref: VHOG:0000981 is_a: UBERON:0004807 ! respiratory system epithelium is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0010499 ! pseudostratified ciliated columnar epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: contributes_to_morphology_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0000072 ! proximo-distal subdivision of respiratory tract [Term] id: UBERON:0004803 name: penis epithelium namespace: uberon def: "An epithelium that is part of a penis [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of penis" EXACT [OBOL:automatic] synonym: "epithelium of penis" EXACT [OBOL:automatic] synonym: "penis epithelial tissue" EXACT [OBOL:automatic] xref: EHDAA2:0004039 xref: EMAPA:35674 xref: MA:0001742 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000989 ! penis relationship: part_of UBERON:0000989 ! penis [Term] id: UBERON:0004804 name: oviduct epithelium namespace: uberon def: "An epithelium that is part of a oviduct [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "columnar epithelium of the fallopian tube" RELATED [BTO:0002402] synonym: "columnar epithelium of the oviduct" RELATED [BTO:0002402] synonym: "epithelial tissue of oviduct" EXACT [OBOL:automatic] synonym: "epithelium of fallopian tube" EXACT [OBOL:automatic] synonym: "epithelium of oviduct" EXACT [OBOL:automatic] synonym: "epithelium of uterine tube" EXACT [FMA:62016] synonym: "fallopian tube epithelium" RELATED [BTO:0002402] synonym: "oviduct epithelial tissue" EXACT [OBOL:automatic] xref: BTO:0002402 xref: CALOHA:TS-1316 xref: EMAPA:29043 xref: MA:0001718 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000993 ! oviduct relationship: part_of UBERON:0003889 ! fallopian tube property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "in FMA, epithelium of uterine tube is a subclass of ciliated columnar epithelium. MA introduces subtypes: ciliated columnar and cuboidal. We map the FMA type according to its relationships, not its label" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004805 name: seminal vesicle epithelium namespace: uberon def: "An epithelium that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of seminal gland" EXACT [OBOL:automatic] synonym: "epithelial tissue of seminal vesicle" EXACT [OBOL:automatic] synonym: "epithelium of seminal gland" EXACT [OBOL:automatic] synonym: "epithelium of seminal vesicle" EXACT [OBOL:automatic] synonym: "seminal gland epithelial tissue" EXACT [OBOL:automatic] synonym: "seminal gland epithelium" EXACT [OBOL:automatic] synonym: "seminal vesicle epithelial tissue" EXACT [OBOL:automatic] xref: CALOHA:TS-2069 xref: EMAPA:29771 xref: MA:0001745 xref: NCIT:C49295 xref: UMLS:C1710049 {source="ncithesaurus:Seminal_Vesicle_Epithelium"} is_a: UBERON:0004910 ! epithelium of male gonad is_a: UBERON:0012275 ! meso-epithelium is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: part_of UBERON:0000998 ! seminal vesicle [Term] id: UBERON:0004806 name: vas deferens epithelium namespace: uberon def: "An epithelium that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] synonym: "deferent duct epithelial tissue" EXACT [OBOL:automatic] synonym: "deferent duct epithelium" EXACT [OBOL:automatic] synonym: "ductus deferens epithelial tissue" EXACT [OBOL:automatic] synonym: "ductus deferens epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of deferent duct" EXACT [OBOL:automatic] synonym: "epithelial tissue of ductus deferens" EXACT [OBOL:automatic] synonym: "epithelial tissue of sperm duct" EXACT [OBOL:automatic] synonym: "epithelial tissue of vas deferen" EXACT [OBOL:automatic] synonym: "epithelial tissue of vas deferens" EXACT [OBOL:automatic] synonym: "epithelium of deferent duct" EXACT [OBOL:automatic] synonym: "epithelium of ductus deferens" EXACT [OBOL:automatic] synonym: "epithelium of sperm duct" EXACT [OBOL:automatic] synonym: "epithelium of vas deferen" EXACT [OBOL:automatic] synonym: "epithelium of vas deferens" EXACT [OBOL:automatic] synonym: "sperm duct epithelial tissue" EXACT [OBOL:automatic] synonym: "sperm duct epithelium" EXACT [OBOL:automatic] synonym: "vas deferen epithelial tissue" EXACT [OBOL:automatic] synonym: "vas deferen epithelium" EXACT [OBOL:automatic] synonym: "vas deferens epithelial tissue" EXACT [OBOL:automatic] xref: EMAPA:29274 xref: FMA:225317 xref: MA:0001749 xref: NCIT:C49315 xref: UMLS:C1710617 {source="ncithesaurus:Vas_Deferens_Epithelium"} is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001000 ! vas deferens relationship: part_of UBERON:0001000 ! vas deferens [Term] id: UBERON:0004807 name: respiratory system epithelium namespace: uberon def: "An epithelium that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "apparatus respiratorius epithelial tissue" EXACT [OBOL:automatic] synonym: "apparatus respiratorius epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "epithelial tissue of respiratory system" EXACT [OBOL:automatic] synonym: "epithelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "epithelium of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system epithelial tissue" EXACT [OBOL:automatic] xref: CALOHA:TS-0023 xref: EMAPA:32826 xref: MA:0001823 xref: VHOG:0000981 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0004808 name: gastrointestinal system epithelium namespace: uberon def: "An epithelium that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] synonym: "digestive system epithelial tissue" EXACT [OBOL:automatic] synonym: "digestive system epithelium" EXACT [OBOL:automatic] synonym: "epithelial tissue of digestive system" EXACT [OBOL:automatic] synonym: "epithelial tissue of gastrointestinal system" EXACT [OBOL:automatic] synonym: "epithelium of digestive system" EXACT [OBOL:automatic] synonym: "epithelium of gastrointestinal system" EXACT [OBOL:automatic] synonym: "gastrointestinal system epithelial tissue" EXACT [OBOL:automatic] xref: EMAPA:32683 xref: MA:0001520 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system [Term] id: UBERON:0004810 name: nephron tubule epithelium namespace: uberon def: "The cellular avascular layer of the renal tubule luminar surfaces." [MGI:csmith, MP:0009640] subset: pheno_slim synonym: "kidney tubule epithelium" EXACT [MA:0001681] xref: BTO:0005239 xref: EMAPA:36524 xref: MA:0001681 xref: NCIT:C49276 xref: UMLS:C1709902 {source="ncithesaurus:Renal_Tubule_Epithelium"} is_a: UBERON:0004211 ! nephron epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: adjacent_to UBERON:0000464 ! anatomical space intersection_of: part_of UBERON:0001231 ! nephron tubule relationship: adjacent_to UBERON:0000464 ! anatomical space relationship: contributes_to_morphology_of UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0001231 ! nephron tubule property_value: editor_note "See https://github.com/obophenotype/uberon/issues/1305" xsd:string [Term] id: UBERON:0004811 name: endometrium epithelium namespace: uberon def: "An epithelium that is part of an endometrium [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "endometrium epithelial tissue" EXACT [OBOL:automatic] synonym: "epithelial tissue of endometrium" EXACT [OBOL:automatic] synonym: "epithelium of endometrium" EXACT [OBOL:automatic] synonym: "epithelium of tunica mucosa of endometrium" EXACT [OBOL:automatic] synonym: "uterine epithelium" RELATED [PMID:19829370] xref: EMAPA:35307 xref: MA:0002731 xref: SCTID:253526009 is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0006955 ! uterine epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001295 ! endometrium relationship: part_of UBERON:0001295 ! endometrium property_value: UBPROP:0000008 "In rodents and primates, the uterine epithelium (the endometrium) is eroded away so that maternal blood comes into direct contact with the trophoblast surface (called haemochorial)" xsd:string {source="PMID:19829370"} [Term] id: UBERON:0004813 name: seminiferous tubule epithelium namespace: uberon def: "The stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule." [MGI:csmith, MP:0011750] subset: pheno_slim synonym: "epithelial tissue of seminiferous tubule" EXACT [OBOL:automatic] synonym: "epithelial tissue of seminiferous tubule of testis" EXACT [OBOL:automatic] synonym: "epithelium of seminiferous tubule" EXACT [OBOL:automatic] synonym: "epithelium of seminiferous tubule of testis" EXACT [OBOL:automatic] synonym: "germinal epithelium (male)" EXACT [Wikipedia:Germinal_epithelium_(male)] synonym: "male germinal epithelium" EXACT [Wikipedia:Germinal_epithelium_(male)] synonym: "seminiferous epithelium" EXACT [BTO:0001811] synonym: "seminiferous tubule epithelial tissue" EXACT [OBOL:automatic] synonym: "testis germinal epithelium" EXACT [VHOG:0000631] synonym: "wall of seminiferous tubule" EXACT [Wikipedia:Germinal_epithelium_(male)] xref: BTO:0001811 xref: CALOHA:TS-0920 xref: EHDAA:8148 xref: EMAPA:35761 xref: FMA:19885 xref: GAID:401 xref: MA:0001748 xref: MESH:D012670 xref: NCIT:C49296 xref: RETIRED_EHDAA2:0002009 xref: UMLS:C0036629 {source="ncithesaurus:Seminiferous_Epithelium"} xref: VHOG:0000631 xref: Wikipedia:Germinal_epithelium_(male) is_a: UBERON:0001136 ! mesothelium is_a: UBERON:0004910 ! epithelium of male gonad is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001343 ! seminiferous tubule of testis relationship: contributes_to_morphology_of UBERON:0001343 ! seminiferous tubule of testis relationship: has_part CL:0000020 ! spermatogonium relationship: has_part CL:0000216 ! Sertoli cell relationship: part_of UBERON:0001343 ! seminiferous tubule of testis [Term] id: UBERON:0004814 name: upper respiratory tract epithelium namespace: uberon def: "An epithelium that is part of a upper respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of upper respiratory tract" EXACT [OBOL:automatic] synonym: "epithelium of upper respiratory tract" EXACT [OBOL:automatic] synonym: "upper respiratory tract epithelial tissue" EXACT [OBOL:automatic] xref: EMAPA:35894 xref: MA:0001912 is_a: UBERON:0004802 ! respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001557 ! upper respiratory tract relationship: part_of UBERON:0001557 ! upper respiratory tract [Term] id: UBERON:0004815 name: lower respiratory tract epithelium namespace: uberon def: "An epithelium that is part of a lower respiratory tract [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of lower respiratory tract" EXACT [OBOL:automatic] synonym: "epithelium of lower respiratory tract" EXACT [OBOL:automatic] synonym: "lower respiratory tract epithelial tissue" EXACT [OBOL:automatic] xref: EMAPA:37549 {source="MA:th"} xref: MA:0001481 is_a: UBERON:0004802 ! respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001558 ! lower respiratory tract relationship: part_of UBERON:0001558 ! lower respiratory tract [Term] id: UBERON:0004816 name: larynx epithelium namespace: uberon def: "An epithelium that is part of a larynx [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "epithelial tissue of larynx" EXACT [OBOL:automatic] synonym: "epithelium of larynx" EXACT [OBOL:automatic] synonym: "laryngeal epithelium" EXACT [OBOL:automatic] synonym: "larynx epithelial tissue" EXACT [OBOL:automatic] xref: EHDAA2:0004065 xref: EMAPA:35472 xref: MA:0001765 xref: NCIT:C49247 xref: UMLS:C0751258 {source="ncithesaurus:Laryngeal_Epithelium"} is_a: UBERON:0004802 ! respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001737 ! larynx relationship: contributes_to_morphology_of UBERON:0001737 ! larynx relationship: part_of UBERON:0001737 ! larynx property_value: UBPROP:0000010 "composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx [ISBN:0-397-51047-0]" xsd:string [Term] id: UBERON:0004819 name: kidney epithelium namespace: uberon def: "The cellular avascular layer of the kidney luminar surfaces." [MGI:csmith, MP:0004967] subset: pheno_slim synonym: "epithelial tissue of kidney" EXACT [OBOL:automatic] synonym: "epithelium of kidney" EXACT [OBOL:automatic] synonym: "kidney epithelial tissue" EXACT [OBOL:automatic] synonym: "renal epithelium" RELATED [EMAPA:35457] xref: BTO:0000059 xref: CALOHA:TS-0505 xref: EMAPA:35457 xref: MA:0002846 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002113 ! kidney relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0004820 name: bile duct epithelium namespace: uberon def: "Any epithelium that lines one of the bile ducts." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "biliary duct epithelium" EXACT [OBOL:automatic] synonym: "epithelium of bile duct" EXACT [OBOL:automatic] synonym: "epithelium of biliary duct" EXACT [OBOL:automatic] xref: BTO:0000417 xref: MA:0001629 xref: NCIT:C43616 xref: UMLS:C1711208 {source="ncithesaurus:Bile_Duct_Epithelium"} is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0034932 ! epithelium of biliary system is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002394 ! bile duct relationship: has_part CL:1000488 ! cholangiocyte relationship: part_of UBERON:0002394 ! bile duct property_value: UBPROP:0000001 "The irregularly shaped proliferating bile ducts are lined by normal cuboidal epithelium." xsd:string {source="BTO:0000417"} [Term] id: UBERON:0004822 name: extrahepatic bile duct epithelium namespace: uberon def: "An epithelium that is part of a extrahepatic bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of extrahepatic bile duct" EXACT [OBOL:automatic] synonym: "epithelium of extrahepatic bile duct" EXACT [OBOL:automatic] synonym: "extrahepatic bile duct epithelial tissue" EXACT [OBOL:automatic] xref: EHDAA2:0000742 xref: EHDAA:3051 xref: MA:0002661 xref: NCIT:C43618 xref: UMLS:C1711347 {source="ncithesaurus:Extrahepatic_Bile_Duct_Epithelium"} is_a: UBERON:0004820 ! bile duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003703 ! extrahepatic bile duct relationship: part_of UBERON:0003703 ! extrahepatic bile duct [Term] id: UBERON:0004823 name: intrahepatic bile duct epithelium namespace: uberon def: "An epithelium that is part of a intrahepatic bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "epithelial tissue of intrahepatic bile duct" EXACT [OBOL:automatic] synonym: "epithelium of intrahepatic bile duct" EXACT [OBOL:automatic] synonym: "intrahepatic bile duct epithelial tissue" EXACT [OBOL:automatic] xref: EHDAA2:0000743 xref: EHDAA:3053 xref: MA:0002662 xref: NCIT:C43617 xref: UMLS:C1708552 {source="ncithesaurus:Intrahepatic_Bile_Duct_Epithelium"} is_a: UBERON:0004820 ! bile duct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003704 ! intrahepatic bile duct relationship: part_of UBERON:0003704 ! intrahepatic bile duct [Term] id: UBERON:0004829 name: urethra skeletal muscle tissue namespace: uberon def: "A portion of skeletal muscle tissue that is part of a urethra [Automatically generated definition]." [OBOL:automatic] synonym: "skeletal muscle of urethra" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of urethra" EXACT [OBOL:automatic] synonym: "urethra skeletal muscle" RELATED [MA:0001690] synonym: "urethra skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "urethral skeletal muscle" RELATED [MA:0001690] xref: EMAPA:37788 {source="MA:th"} xref: MA:0001690 is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0003829 ! urethra muscle tissue [Term] id: UBERON:0004830 name: respiratory system skeletal muscle namespace: uberon def: "A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] synonym: "respiratory system skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "skeletal muscle of respiratory system" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37583 {source="MA:th"} xref: MA:0001829 is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0004831 name: esophagus skeletal muscle namespace: uberon def: "A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]." [OBOL:automatic] comment: Most muscle tissue lining the digestive tract is smooth, but part of the externa of the esophagus is skeletal synonym: "esophagus skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of esophagus" EXACT [OBOL:automatic] xref: EMAPA:36523 xref: MA:0001572 is_a: UBERON:0003898 ! skeletal muscle tissue of trunk intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0003832 ! esophagus muscle [Term] id: UBERON:0004832 name: anal region skeletal muscle namespace: uberon def: "A portion of skeletal muscle tissue that is part of an anal region [Automatically generated definition]." [OBOL:automatic] synonym: "anal part of perineum skeletal muscle" EXACT [OBOL:automatic] synonym: "anal part of perineum skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "anal region skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "anal triangle skeletal muscle" EXACT [OBOL:automatic] synonym: "anal triangle skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of anal part of perineum" EXACT [OBOL:automatic] synonym: "skeletal muscle of anal region" EXACT [OBOL:automatic] synonym: "skeletal muscle of anal triangle" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of anal part of perineum" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of anal region" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of anal triangle" EXACT [OBOL:automatic] xref: EMAPA:37393 {source="MA:th"} xref: MA:0001530 is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001353 ! anal region relationship: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0004833 name: lip skeletal muscle namespace: uberon def: "A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]." [OBOL:automatic] synonym: "lip skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle of lip" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue of lip" EXACT [OBOL:automatic] xref: EMAPA:37642 {source="MA:th"} xref: MA:0001578 is_a: UBERON:0001134 ! skeletal muscle tissue intersection_of: UBERON:0001134 ! skeletal muscle tissue intersection_of: part_of UBERON:0001833 ! lip relationship: part_of UBERON:0001833 ! lip property_value: editor_note "this class is derived from MA. Consider re-modeling this as being a muscle that acts on the lips. See: Wikipedia:Lip#Muscles_acting_on_the_lips" xsd:string [Term] id: UBERON:0004834 name: hepatic duct smooth muscle namespace: uberon def: "Smooth muscle tissue in all or part of a hepatic duct." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37598 {source="MA:th"} xref: MA:0001640 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005171 ! hepatic duct relationship: part_of UBERON:0005171 ! hepatic duct [Term] id: UBERON:0004835 name: epididymis smooth muscle namespace: uberon def: "A portion of smooth muscle tissue that is part of a epididymis [Automatically generated definition]." [OBOL:automatic] synonym: "epididymis involuntary muscle" EXACT [OBOL:automatic] synonym: "epididymis non-striated muscle" EXACT [OBOL:automatic] synonym: "epididymis smooth muscle tissue" EXACT [OBOL:automatic] synonym: "involuntary muscle of epididymis" EXACT [OBOL:automatic] synonym: "non-striated muscle of epididymis" EXACT [OBOL:automatic] synonym: "smooth muscle of epididymis" EXACT [OBOL:automatic] synonym: "smooth muscle tissue of epididymis" EXACT [OBOL:automatic] xref: EMAPA:30747 xref: MA:0001736 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0001301 ! epididymis [Term] id: UBERON:0004848 name: respiratory system arterial endothelium namespace: uberon def: "An endothelium of artery that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "apparatus respiratorius arterial endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius artery endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius endothelium of artery" EXACT [OBOL:automatic] synonym: "arterial endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "arterial endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "artery endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "artery endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "endothelium of artery of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of artery of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system artery endothelium" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of artery" EXACT [OBOL:automatic] xref: EMAPA:37566 {source="MA:th"} xref: MA:0001801 is_a: UBERON:0001917 ! endothelium of artery is_a: UBERON:0004702 ! respiratory system blood vessel endothelium intersection_of: UBERON:0001917 ! endothelium of artery intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003469 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! respiratory system artery property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004849 name: respiratory system venous endothelium namespace: uberon def: "An endothelium of vein that is part of a respiratory system [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "apparatus respiratorius endothelium of vein" EXACT [OBOL:automatic] synonym: "apparatus respiratorius vein endothelium" EXACT [OBOL:automatic] synonym: "apparatus respiratorius venous endothelium" EXACT [OBOL:automatic] synonym: "endothelium of vein of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "endothelium of vein of respiratory system" EXACT [OBOL:automatic] synonym: "respiratory system endothelium of vein" EXACT [OBOL:automatic] synonym: "respiratory system vein endothelium" EXACT [OBOL:automatic] synonym: "vein endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "vein endothelium of respiratory system" EXACT [OBOL:automatic] synonym: "venous endothelium of apparatus respiratorius" EXACT [OBOL:automatic] synonym: "venous endothelium of respiratory system" EXACT [OBOL:automatic] xref: EMAPA:37585 {source="MA:th"} xref: MA:0001811 is_a: UBERON:0001919 ! endothelium of vein is_a: UBERON:0004702 ! respiratory system blood vessel endothelium intersection_of: UBERON:0001919 ! endothelium of vein intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003476 ! respiratory system venous blood vessel property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004851 name: aorta endothelium namespace: uberon def: "The thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall." [MGI:csmith, MP:0009864] subset: efo_slim subset: pheno_slim synonym: "adult aorta endothelium" EXACT [OBOL:automatic] synonym: "aortic endothelium" RELATED [BTO:0000394] synonym: "endothelium of adult aorta" EXACT [OBOL:automatic] synonym: "endothelium of aorta" EXACT [OBOL:automatic] synonym: "endothelium of trunk of aortic tree" EXACT [OBOL:automatic] synonym: "endothelium of trunk of systemic arterial tree" EXACT [OBOL:automatic] synonym: "trunk of aortic tree endothelium" EXACT [OBOL:automatic] synonym: "trunk of systemic arterial tree endothelium" EXACT [OBOL:automatic] xref: BTO:0000394 xref: CALOHA:TS-0047 xref: EFO:0002597 xref: EMAPA:35134 xref: MA:0000701 xref: NCIT:C49190 xref: UMLS:C1706824 {source="ncithesaurus:Aorta_Endothelium"} is_a: UBERON:0004638 ! blood vessel endothelium is_a: UBERON:0004700 ! arterial system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000947 ! aorta relationship: part_of UBERON:0000947 ! aorta [Term] id: UBERON:0004852 name: cardiovascular system endothelium namespace: uberon def: "An endothelium that is part of the cardiovascular system." [https://orcid.org/0000-0002-6601-2165] subset: vertebrate_core synonym: "endothelia" RELATED PLURAL [ZFA:0001639] synonym: "vascular endothelia" RELATED PLURAL [XAO:0000356] xref: BTO:0001853 xref: EMAPA:35201 xref: GAID:519 xref: MA:0000717 xref: MESH:D004730 xref: NCIT:C13053 xref: TAO:0002171 xref: UMLS:C0014261 {source="ncithesaurus:Vascular_Endothelium"} xref: VHOG:0001217 xref: XAO:0000356 xref: ZFA:0001639 is_a: UBERON:0001986 ! endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0004535 ! cardiovascular system relationship: part_of UBERON:0004535 ! cardiovascular system property_value: editor_note "consider merging with 'endothelium'" xsd:string property_value: UBPROP:0000003 "Vertebrates and a very few invertebrates such as squids have evolved a secondary epithelium, the endothelium, that lines their blood vessels.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001217", ontology="VHOG", source="ISBN:978-0030259821 Ruppert EE, Fox RS, Barnes RD, Invertebrate zoology: a functional evolutionary approach (2003) p.207", source="http://bgee.unil.ch/"} [Term] id: UBERON:0004854 name: gastrointestinal system mesentery namespace: uberon def: "A mesentery that is part of a digestive system [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "digestive system mesentery" EXACT [OBOL:automatic] synonym: "mesentery of digestive system" EXACT [OBOL:automatic] synonym: "mesentery of gastrointestinal system" EXACT [OBOL:automatic] xref: EMAPA:37068 {source="MA:th"} xref: MA:0001900 is_a: UBERON:0002095 ! mesentery is_a: UBERON:0004782 ! gastrointestinal system serosa intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system [Term] id: UBERON:0004857 name: skeletal muscle connective tissue namespace: uberon def: "A connective tissue that surrounds a skeletal muscle tissue." [OBOL:automatic] synonym: "connective tissue of skeletal muscle" EXACT [OBOL:automatic] synonym: "connective tissue of skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "portion of connective tissue of skeletal muscle" EXACT [OBOL:automatic] synonym: "portion of connective tissue of skeletal muscle tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle interstitial tissue" RELATED [MA:0002868] synonym: "skeletal muscle interstitum" RELATED [MA:0002868] synonym: "skeletal muscle portion of connective tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle textus connectivus" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue connective tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue portion of connective tissue" EXACT [OBOL:automatic] synonym: "skeletal muscle tissue textus connectivus" EXACT [OBOL:automatic] synonym: "textus connectivus of skeletal muscle" EXACT [OBOL:automatic] synonym: "textus connectivus of skeletal muscle tissue" EXACT [OBOL:automatic] xref: EMAPA:37743 {source="MA:th"} xref: MA:0002868 is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: surrounds UBERON:0001134 ! skeletal muscle tissue relationship: surrounds UBERON:0001134 ! skeletal muscle tissue [Term] id: UBERON:0004859 name: eye gland namespace: uberon def: "A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid." [http://orcid.org/0000-0002-6601-2165] comment: Examples: harderian gland, accessory lacrimal gland, gland of Moll, gland of Zeis, nictitating membrane glands subset: organ_slim synonym: "eye-associated gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "gland of eye" EXACT [OBOL:automatic] xref: EMAPA:35334 xref: MA:0000267 is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000970 ! eye relationship: part_of UBERON:0000970 ! eye [Term] id: UBERON:0004864 name: vasculature of retina namespace: uberon def: "A vasculature that is part of a retina [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "retina vasculature" EXACT [GO:0061298] synonym: "retina vasculature of camera-type eye" EXACT [GO:0061298] synonym: "retinal blood vessels" EXACT [FMA:76552] synonym: "retinal blood vessels set" EXACT [FMA:76552] synonym: "retinal vasculature" EXACT [OBOL:automatic] synonym: "set of blood vessels of retina" EXACT [OBOL:automatic] synonym: "set of retinal blood vessels" EXACT [FMA:76552] synonym: "vasa sanguinea retinae" EXACT LATIN [FMA:76552, FMA:TA] xref: FMA:76552 xref: MESH:D012171 xref: XAO:0004153 is_a: UBERON:0002203 ! vasculature of eye is_a: UBERON:0036302 ! vasculature of central nervous system plus retina intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000966 ! retina relationship: part_of UBERON:0000966 ! retina property_value: RO:0002161 NCBITaxon:8782 {source="PMID:21622558", source="PMID:2772405", submitter="michaelerice"} property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004865 name: actinopterygian parietal bone namespace: uberon def: "Dermal bone that covers the otic region and may articulate with its antimere medially, with the frontal bone anteriorly, the pterotic laterally, the supraoccipital medio-posteriorly, and the epiotic and extrascapula latero-posteriorly. The parietal is a paired bone.[TAO]." [TAO:0000486, TAO:GA_TG] synonym: "actinopterygian parietal" EXACT [] synonym: "frontal bone" NARROW [FMA:52734] synonym: "parietal bone" NARROW SENSU [TAO:0000486] synonym: "parietals" RELATED PLURAL [TAO:0000486] synonym: "post parietal" RELATED [ZFA:0000486] xref: TAO:0000486 xref: VHOG:0001327 xref: ZFA:0000486 is_a: UBERON:0002514 ! intramembranous bone is_a: UBERON:0008907 ! dermal bone is_a: UBERON:0011164 ! neurocranium bone relationship: part_of UBERON:0003110 {source="ZFA"} ! otic region relationship: part_of UBERON:0003113 {source="ZFA"} ! dermatocranium relationship: part_of UBERON:0004339 {source="PMID:11523816"} ! vault of skull property_value: UBPROP:0000001 "Dermal bone that covers the otic region and may articulate with its antimere medially, with the frontal bone anteriorly, the pterotic laterally, the supraoccipital medio-posteriorly, and the epiotic and extrascapula latero-posteriorly. The parietal is a paired bone.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000486", ontology="TAO", source="TAO:GA_TG"} property_value: UBPROP:0000002 "relationship loss: overlaps frontal-parietal joint (TAO:0005255)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000486", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: overlaps inter-parietal joint (TAO:0005245)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000486", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: overlaps posttemporal-parietal joint (TAO:0002059)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000486", ontology="TAO"} property_value: UBPROP:0000002 "relationship loss: overlaps supraoccipital-parietal joint (TAO:0005264)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000486", ontology="TAO"} property_value: UBPROP:0000003 "The homologization of cranial bones of actinopterygians with those of sarcopterygians based on the bone names established in human anatomy is favored in order to permit the building of phylogenetic relationship schemes beyond the taxonomic boundaries of osteichthyans (including tetrapods). (...) In actinopterygians, the terms parietal and postparietal bones have to replace the commonly used terms 'frontal' and 'parietal' bones for the two paired bones on the skull roof.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001327", ontology="VHOG", source="ISBN:978-3899370805 Arratia G, Schultze HP, Wilson MVH, Mesozoic Fishes 4 - Homology and Phylogeny (2008) p.23-48", source="http://bgee.unil.ch/"} property_value: UBPROP:0000005 "The parietal is a flat, commonly squarish or rectangular bone.[TAO]" xsd:string {date_retrieved="2012-09-06", external_class="TAO:0000486", ontology="TAO", source="Curator"} [Term] id: UBERON:0004867 name: orbital cavity namespace: uberon def: "Anatomical cavity bounded by the orbital region of the cranium and forming the location of some or all of the eye." [http://orcid.org/0000-0002-6601-2165] synonym: "orbit" RELATED [AAO:0000343] xref: AAO:0000343 xref: FMA:84961 xref: SCTID:280541000 xref: Wikipedia:Orbit_(anatomy) xref: ZFA:0005558 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0001697 ! orbit of skull relationship: luminal_space_of UBERON:0001697 ! orbit of skull relationship: part_of UBERON:0001697 ! orbit of skull property_value: UBPROP:0000012 "note that the AAO and ZFA class is a cavity" xsd:string {external_ontology="AAO", seeAlso="https://github.com/obophenotype/uberon/issues/462"} [Term] id: UBERON:0004871 name: somatic layer of lateral plate mesoderm namespace: uberon def: "Layer of lateral plate mesoderm that forms the future body wall - underlies the ectoderm[WP]." [Wikipedia:Lateral_plate_mesoderm#Division_into_layers] subset: pheno_slim synonym: "outer layer of lateral plate mesoderm" EXACT [] synonym: "parietal mesoderm" RELATED [ISBN:9780878932504] synonym: "somatic mesoderm" RELATED [BILA:0000047] xref: AAO:0011100 xref: BILA:0000047 xref: FMA:295570 xref: Wikipedia:Lateral_plate_mesoderm#Division_into_layers xref: XAO:0000271 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0003081 ! lateral plate mesoderm property_value: editor_note "check BILA" xsd:string [Term] id: UBERON:0004872 name: splanchnic layer of lateral plate mesoderm namespace: uberon def: "Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]." [Wikipedia:Lateral_plate_mesoderm#Division_into_layers] subset: pheno_slim synonym: "inner layer of lateral plate mesoderm" EXACT [] synonym: "splanchnic mesoderm" RELATED [ISBN:9780878932504] synonym: "visceral mesoderm" BROAD [BILA:0000044, http://www.drugs.com/dict/visceral-mesoderm.html, http://www.stedmans.com/] xref: AAO:0011102 xref: BILA:0000044 xref: FMA:295568 xref: Wikipedia:Lateral_plate_mesoderm#Division_into_layers xref: XAO:0000276 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0003081 ! lateral plate mesoderm property_value: UBPROP:0000012 "We group the BILA class here. Considering adding more general class for metazoa grouping cardiogenic successors" xsd:string {external_ontology="BILA"} [Term] id: UBERON:0004873 name: splanchnopleure namespace: uberon def: "A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]." [Wikipedia:Splanchnopleure] synonym: "ventral splanchnic mesoderm" RELATED [Wikipedia:Intraembryonic_coelom] xref: EHDAA2:0001903 xref: EHDAA:383 xref: EMAPA:16181 xref: FMA:295564 xref: NCIT:C34303 xref: UMLS:C1519472 {source="ncithesaurus:Splanchnopleure"} xref: VHOG:0000558 xref: Wikipedia:Splanchnopleure is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: overlaps UBERON:0000925 ! endoderm relationship: part_of UBERON:0003081 {source="EHDAA2"} ! lateral plate mesoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png" xsd:anyURI property_value: editor_note "TODO - check relationship to LPM" xsd:string [Term] id: UBERON:0004874 name: somatopleure namespace: uberon def: "A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]." [Wikipedia:Somatopleure] xref: EHDAA2:0001847 xref: EHDAA:381 xref: EMAPA:16180 xref: FMA:295566 xref: NCIT:C34301 xref: UMLS:C1519423 {source="ncithesaurus:Somatopleure"} xref: VHOG:0000557 xref: Wikipedia:Somatopleure is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: overlaps UBERON:0000924 ! ectoderm relationship: part_of UBERON:0003081 {source="EHDAA2"} ! lateral plate mesoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/28/Gray16.png" xsd:anyURI property_value: UBPROP:0000011 "Gives rise to the paired appendages in jawed vertebrates. a persistent somatopleure through the redistribution and expansion of the lateral plate mesoderm is a synapomorphy for gnathostomes and a critical step in generating a novel developmental module with dramatic evolutionary potentia (Tulenko et al. 2012) http://burkelab.research.wesleyan.edu/current-projects/lamprey/" xsd:string property_value: UBPROP:0000012 "sources differ as to whether this is part-of or develops-from the LPM" xsd:string [Term] id: UBERON:0004875 name: nephrogenic cord namespace: uberon def: "A portion of the urogenital ridge which is the source of much of the urinary system[WP]." [Wikipedia:Nephrogenic_cord] comment: part_of or develops_from urogenital ridge? synonym: "chorda nephrogenica" RELATED LATIN [Wikipedia:Nephrogenic_cord] xref: FMA:72168 xref: NCIT:C34219 xref: SCTID:361405003 xref: UMLS:C1283944 {source="ncithesaurus:Nephrogenic_Cord"} xref: Wikipedia:Nephrogenic_cord is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0004876 ! urogenital fold [Term] id: UBERON:0004876 name: urogenital fold namespace: uberon def: "One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]." [MP:0011835, MP:anna, Wikipedia:Urogenital_folds] subset: pheno_slim synonym: "urethral fold" EXACT [EMAPA:30888] synonym: "urogenital fold" EXACT [EHDAA2:0004022, MP:0011835] synonym: "urogenital ridge" RELATED INCONSISTENT [MP:0011835] xref: EHDAA2:0004022 xref: EMAPA:30888 xref: FMA:321919 xref: Wikipedia:Urogenital_folds is_a: UBERON:0006598 ! presumptive structure relationship: develops_from UBERON:0003064 {source="Wikipedia"} ! intermediate mesoderm relationship: develops_from UBERON:0012292 {source="EHDAA2"} ! embryonic cloacal fold relationship: has_potential_to_develop_into UBERON:0004176 ! external genitalia relationship: part_of UBERON:0009196 {source="EHDAA2"} ! indifferent external genitalia property_value: UBPROP:0000013 "Less commonly, urogenital fold refers to the fold in the mesonephros which is the precursor of e.g. the suspensory ligament of the ovary. This is the case in older versions of Gray's anatomy[WP]" xsd:string [Term] id: UBERON:0004880 name: chordamesoderm namespace: uberon def: "The central region of trunk mesoderm. This tissue forms the notochord." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim synonym: "axial chorda mesoderm" EXACT [ZFA:0000091] synonym: "chorda mesoderm" EXACT [] synonym: "dorsal mesoderm" EXACT [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "presumptive notochord" EXACT [ZFA:0000091] xref: AAO:0000478 xref: EFO:0003426 xref: TAO:0000091 xref: ZFA:0000091 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0003068 ! axial mesoderm property_value: UBPROP:0000001 "Notochord rudiment[ZFIN:ZDB-PUB-961014-576]." xsd:string {source="ZFIN:ZDB-PUB-961014-576"} property_value: UBPROP:0000012 "WP treats this as synonym of axial mesoderm. Induces neural tube. Gilbert: contains an anterior head process and the notochord." xsd:string [Term] id: UBERON:0004883 name: lung mesenchyme namespace: uberon def: "The mass of tissue made up of mesenchymal cells in the lung." [GO:0060484] subset: human_reference_atlas subset: pheno_slim synonym: "lung-associated mesenchyme" EXACT [GO:0060484] synonym: "mesenchyme of lung" EXACT [OBOL:automatic] synonym: "pulmonary mesenchyme" EXACT [GO:0060484] xref: EMAPA:32866 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002048 ! lung relationship: develops_from UBERON:0003081 ! lateral plate mesoderm relationship: part_of UBERON:0002048 ! lung property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004902 name: urogenital sinus epithelium namespace: uberon def: "The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra." [PMID:18977204] synonym: "epithelium of urogenital sinus" EXACT [OBOL:automatic] synonym: "UGE" EXACT [PMID:18977204] xref: EHDAA2:0004061 xref: EMAPA:31509 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0009846 ! embryonic cloacal epithelium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000164 ! primitive urogenital sinus relationship: develops_from UBERON:0009846 {source="EHDAA2"} ! embryonic cloacal epithelium relationship: part_of UBERON:0000164 ! primitive urogenital sinus property_value: UBPROP:0000012 "we follow EHDAA2 in dividing the UGS into epithelium and lumen" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0004904 name: neuron projection bundle connecting eye with brain namespace: uberon def: "A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila." [http://orcid.org/0000-0002-6601-2165] comment: for the vertebrate-specific structure, see UBERON:0000941 (cranial nerve II) subset: grouping_class subset: human_reference_atlas subset: pheno_slim synonym: "optic nerve" BROAD [BTO:0000966] synonym: "optic nerve (generic)" EXACT [] xref: BTO:0000966 xref: EV:0100351 xref: FBbt:00001956 xref: TADS:0000232 is_a: UBERON:0000122 ! neuron projection bundle intersection_of: UBERON:0000122 ! neuron projection bundle intersection_of: extends_fibers_into UBERON:0000955 ! brain intersection_of: extends_fibers_into UBERON:0005388 ! photoreceptor array relationship: extends_fibers_into UBERON:0000955 ! brain relationship: extends_fibers_into UBERON:0005388 ! photoreceptor array relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002104 ! visual system property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004905 name: articulation namespace: uberon def: "Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "joint" NARROW [] xref: FBbt:00005811 is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004770 ! articular system [Term] id: UBERON:0004906 name: ectodermal part of digestive tract namespace: uberon def: "A portion of the gut that is derived from ectoderm." [GO:0007439] synonym: "ectodermal gut" EXACT [] synonym: "gut ectoderm" EXACT [EMAPA:32930] is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004921 ! subdivision of digestive tract intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: develops_from UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0004907 name: lower digestive tract namespace: uberon def: "The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]." [Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract] subset: uberon_slim synonym: "gut" BROAD [GO:0048565] synonym: "lower gastrointestinal tract" EXACT [] synonym: "lower GI tract" EXACT [] xref: FMA:49179 xref: galen:LowerGastrointestinalTract xref: NCIT:C33010 xref: SCTID:279973004 xref: UMLS:C0226875 {source="ncithesaurus:Lower_Gastrointestinal_Tract"} xref: Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract is_a: UBERON:0004921 ! subdivision of digestive tract relationship: develops_from UBERON:0001046 ! hindgut relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system property_value: UBPROP:0000012 "MA class was moved from here. See https://github.com/obophenotype/uberon/issues/509" xsd:string {external_ontology="MA"} property_value: UBPROP:0000012 "WP: small intestine, large intestine, anus. Anal canal not part of LGIT according to FMA, but anus is considered part of LGIT according to WP. Duodenum overlaps both U/L" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004908 name: upper digestive tract namespace: uberon def: "The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum." [Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract] subset: uberon_slim synonym: "upper gastrointestinal tract" EXACT [] synonym: "upper GI tract" EXACT [] xref: FMA:49177 xref: galen:UpperGastrointestinalTract xref: NCIT:C33837 xref: SCTID:181244000 xref: UMLS:C0226874 {source="ncithesaurus:Upper_Gastrointestinal_Tract"} xref: Wikipedia:Alimentary_canal#Upper_gastrointestinal_tract is_a: UBERON:0004921 ! subdivision of digestive tract relationship: develops_from UBERON:0001041 ! foregut property_value: UBPROP:0000012 "WP: small intestine, large intestine, anus. Anal canal not part of LGIT according to FMA, but anus is considered part of LGIT according to WP. Duodenum overlaps both U/L. In Galen, entire GI tract excludes esophagus" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0004909 name: epithelium of gonad namespace: uberon def: "An epithelium surrounding a gonad." [OBOL:automatic] synonym: "gonad epithelium" EXACT [OBOL:automatic] synonym: "gonadal epithelium" EXACT [OBOL:automatic] synonym: "gonadal sheath" RELATED [FBbt:00004859] xref: EHDAA:4032 xref: EHDAA:5931 xref: NCIT:C32676 xref: UMLS:C1517534 {source="ncithesaurus:Germinal_Epithelium"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000483 ! epithelium is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000991 ! gonad relationship: part_of UBERON:0000991 ! gonad property_value: editor_note "after reasoning this should subsume the more specific germinal epithelium classes. We include the fly structure here although it is not clear if the sheath is an epithelium or a multi-tissue structure that includes epithelium as parts" xsd:string [Term] id: UBERON:0004910 name: epithelium of male gonad namespace: uberon def: "An epithelium surrounding a testis." [OBOL:automatic] synonym: "testis epithelium" EXACT [OBOL:automatic] xref: BTO:0001364 xref: EMAPA:17973 is_a: UBERON:0004909 ! epithelium of gonad intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000473 ! testis relationship: part_of UBERON:0000473 ! testis property_value: editor_note "after reasoning this should subsume the more specific germinal epithelium classes. We include the fly structure here although it is not clear if the sheath is an epithelium or a multi-tissue structure that includes epithelium as parts" xsd:string [Term] id: UBERON:0004911 name: epithelium of female gonad namespace: uberon def: "An epithelium surrounding an ovary." [OBOL:automatic] synonym: "ovarian epithelium" EXACT [OBOL:automatic] synonym: "ovarian sheath" NARROW SENSU [FBbt:00004896] synonym: "ovary epithelium" EXACT [OBOL:automatic] xref: BTO:0003661 is_a: UBERON:0004909 ! epithelium of gonad intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0000992 ! ovary property_value: editor_note "after reasoning this should subsume the more specific germinal epithelium classes. We include the fly structure here although it is not clear if the sheath is an epithelium or a multi-tissue structure that includes epithelium as parts" xsd:string [Term] id: UBERON:0004912 name: biliary bud namespace: uberon synonym: "hepatic diverticulum" RELATED [EMAPA:16561] xref: EHDAA2:0000171 xref: EMAPA:16561 xref: EMAPA_RETIRED:16565 xref: VHOG:0001351 is_a: UBERON:0004185 ! endodermal part of digestive tract is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac is_a: UBERON:0009497 ! epithelium of foregut-midgut junction is_a: UBERON:0009854 ! digestive tract diverticulum relationship: develops_from UBERON:0004161 {source="EHDAA2-modified"} ! septum transversum relationship: part_of UBERON:0002423 {source="EHDAA2"} ! hepatobiliary system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png" xsd:anyURI [Term] id: UBERON:0004913 name: hepatopancreatic ampulla namespace: uberon def: "A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct." [Wikipedia:Ampulla_of_Vater] subset: human_reference_atlas subset: vertebrate_core synonym: "ampulla biliaropancreatica" EXACT LATIN [FMA:15076, FMA:TA] synonym: "ampulla hepatopancreatica" RELATED LATIN [Wikipedia:Ampulla_of_Vater] synonym: "ampulla of bile duct" EXACT [FMA:15076] synonym: "ampulla of Vater" EXACT [] synonym: "ampulla Vaterii" RELATED LATIN [Wikipedia:Ampulla_of_Vater] synonym: "biliaropancreatic ampulla" EXACT [] synonym: "papilla duodeni major" RELATED [ZFA:0005167] synonym: "papilla Vateri" EXACT [ZFA:0005167] synonym: "Vater's ampulla" EXACT [] xref: CALOHA:TS-2348 xref: FMA:15076 xref: GAID:283 xref: galen:AmpullaOfVater xref: MESH:D014670 xref: NCIT:C13011 xref: SCTID:362200007 xref: TAO:0005167 xref: UMLS:C0042425 {source="ncithesaurus:Ampulla_of_Vater"} xref: Wikipedia:Ampulla_of_Vater xref: ZFA:0005167 is_a: UBERON:0002394 ! bile duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0001174 ! common bile duct intersection_of: part_of UBERON:0004914 ! duodenal papilla relationship: part_of UBERON:0001174 ! common bile duct relationship: part_of UBERON:0004914 ! duodenal papilla property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Biliary_system_new.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Ampulla formed by the union of the pancreatic duct and the common bile duct where they enter the intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005167", ontology="TAO", source="ZFIN:ZDB-PUB-070212-11", source="ZFIN:ZDB-PUB-080414-12"} [Term] id: UBERON:0004914 name: duodenal papilla namespace: uberon def: "One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct." [http://medical-dictionary.thefreedictionary.com/duodenal+papilla] synonym: "papilla duodenalis" EXACT [] synonym: "papilla duodeni" RELATED LATIN [Wikipedia:Major_duodenal_papilla] synonym: "papilla of duodenum" EXACT [] xref: EMAPA:18662 xref: FMA:15953 xref: MA:0003107 xref: NCIT:C119578 xref: SCTID:245389007 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034944 ! zone of organ relationship: part_of UBERON:0000320 ! duodenal mucosa property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/43/Gray1057.png" xsd:anyURI [Term] id: UBERON:0004915 name: sphincter of hepatopancreatic ampulla namespace: uberon def: "Muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. Relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[WP]." [Wikipedia:Sphincter_of_ampulla] subset: human_reference_atlas synonym: "hepatopancreatic ampullary sphincter" EXACT [FMA:15077] synonym: "musculus sphincter ampullae" EXACT [FMA:15077] synonym: "musculus sphincter ampullae hepatopancreatica" EXACT LATIN [FMA:15077, FMA:TA] synonym: "Oddi's sphincter" EXACT [] synonym: "sphincter of ampulla of vater" EXACT [FMA:15077] synonym: "sphincter of Oddi" EXACT [] xref: EMAPA:18663 xref: FMA:15077 xref: GAID:285 xref: MESH:D009803 xref: NCIT:C13065 xref: SCTID:181271000 xref: UMLS:C0028872 {source="ncithesaurus:Sphincter_of_Oddi"} xref: Wikipedia:Sphincter_of_ampulla is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0011185 ! gastrointestinal sphincter intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0004913 ! hepatopancreatic ampulla relationship: part_of UBERON:0004913 ! hepatopancreatic ampulla property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/43/Gray1057.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004916 name: anal sphincter namespace: uberon def: "A sphincter muscle that is part of a anal region." [OBOL:automatic] synonym: "anal region sphincter" EXACT [] synonym: "sphincter analia" EXACT [] xref: EMAPA:36052 is_a: UBERON:0004590 ! sphincter muscle intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0001353 ! anal region relationship: capable_of_part_of GO:0030421 ! defecation relationship: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0004917 name: urethral sphincter namespace: uberon def: "A sphincter muscle surrounding the urethra." [Wikipedia:Urethral_sphincter] synonym: "sphincter muscle of urethra" EXACT [] synonym: "sphincter of urethra" EXACT [] synonym: "sphincter urethrae" EXACT [] synonym: "urethral sphincter muscle" EXACT [] xref: EMAPA:37789 {source="MA:th"} xref: MA:0002650 xref: SCTID:277855007 xref: SCTID:277857004 xref: Wikipedia:Urethral_sphincter is_a: UBERON:0003829 ! urethra muscle tissue is_a: UBERON:0004590 ! sphincter muscle intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0004921 name: subdivision of digestive tract namespace: uberon def: "A proximal-distal subdivision of the digestive tract." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "alimentary system subdivision" RELATED [FMA:71131] synonym: "gut section" RELATED [FBbt:00100315] synonym: "intestinal tract" RELATED [] synonym: "segment of intestinal tract" RELATED [] synonym: "subdivision of alimentary system" RELATED [FMA:71131] xref: FBbt:00100315 xref: FMA:71131 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: subdivision_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract relationship: subdivision_of UBERON:0001555 ! digestive tract property_value: IAO:0000232 "intended to denote both embryonic and adult structures. Note the FMA grouping here is not quite correct." xsd:string [Term] id: UBERON:0004923 name: organ component layer namespace: uberon def: "A part of a wall of an organ that forms a layer." [http://orcid.org/0000-0002-6601-2165] subset: upper_level xref: FMA:82485 is_a: UBERON:0000064 ! organ part relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000060 ! anatomical wall [Term] id: UBERON:0004924 name: submucosa of pharynx namespace: uberon def: "The tissue underlying the tunica mucosa of the pharynx." [BTO:0002113] synonym: "pharyngeal submucosa" EXACT [FMA:75144] synonym: "pharyngobasilar fascia" RELATED [] synonym: "pharynx submucosa" EXACT [OBOL:automatic] synonym: "submucous coat of pharynx" RELATED [BTO:0002113] synonym: "submucous layer of pharynx" RELATED [BTO:0002113] synonym: "tela submucosa pharyngea" EXACT LATIN [FMA:75144, FMA:TA] synonym: "tela submucosa pharyngis" EXACT LATIN [BTO:0002113] xref: BTO:0002113 xref: FMA:75144 xref: SCTID:19594009 is_a: UBERON:0004777 ! respiratory system submucosa is_a: UBERON:0018257 ! submucosa of digestive tract intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 ! chordate pharynx [Term] id: UBERON:0004926 name: submucosa of cystic duct namespace: uberon def: "A submucosa that is part of a cystic duct [Automatically generated definition]." [OBOL:automatic] synonym: "cystic duct submucosa" EXACT [OBOL:automatic] synonym: "cystic ductal submucosa" EXACT [FMA:18013] xref: FMA:18013 is_a: UBERON:0004938 ! submucosa of biliary tree intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001152 ! cystic duct relationship: part_of UBERON:0001152 ! cystic duct [Term] id: UBERON:0004932 name: submucosa of sigmoid colon namespace: uberon def: "A submucosa that is part of a sigmoid colon [Automatically generated definition]." [OBOL:automatic] synonym: "sigmoid colon submucosa" EXACT [OBOL:automatic] xref: FMA:15027 is_a: UBERON:0003331 ! submucosa of colon intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001159 ! sigmoid colon relationship: part_of UBERON:0001159 ! sigmoid colon [Term] id: UBERON:0004934 name: submucosa of body of stomach namespace: uberon def: "A submucosa that is part of a body of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "body of stomach submucosa" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) submucosa" EXACT [OBOL:automatic] synonym: "gastric body submucosa" EXACT [OBOL:automatic] synonym: "stomach body submucosa" EXACT [OBOL:automatic] synonym: "submucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "submucosa of gastric body" EXACT [OBOL:automatic] synonym: "submucosa of stomach body" EXACT [OBOL:automatic] xref: FMA:17059 is_a: UBERON:0001200 ! submucosa of stomach intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001161 ! body of stomach relationship: part_of UBERON:0001161 ! body of stomach [Term] id: UBERON:0004936 name: submucosa of pyloric antrum namespace: uberon def: "A submucosa that is part of a pyloric antrum [Automatically generated definition]." [OBOL:automatic] synonym: "antrum of stomach submucosa" EXACT [OBOL:automatic] synonym: "pyloric antrum submucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum submucosa" EXACT [OBOL:automatic] synonym: "submucosa of antrum of stomach" EXACT [OBOL:automatic] synonym: "submucosa of stomach pyloric antrum" EXACT [OBOL:automatic] xref: FMA:17060 is_a: UBERON:0004937 ! submucosa of pylorus intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001165 ! pyloric antrum relationship: part_of UBERON:0001165 ! pyloric antrum [Term] id: UBERON:0004937 name: submucosa of pylorus namespace: uberon def: "A submucosa that is part of a pylorus [Automatically generated definition]." [OBOL:automatic] synonym: "pyloric part of stomach submucosa" EXACT [OBOL:automatic] synonym: "pyloric submucosa" EXACT [] synonym: "pylorus submucosa" EXACT [FMA:17462, OBOL:automatic] synonym: "stomach pyloric region submucosa" EXACT [OBOL:automatic] synonym: "submucosa of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "submucosa of stomach pyloric region" EXACT [OBOL:automatic] xref: EMAPA:27201 xref: FMA:17462 is_a: UBERON:0001200 ! submucosa of stomach intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001166 ! pylorus relationship: part_of UBERON:0001166 ! pylorus [Term] id: UBERON:0004938 name: submucosa of biliary tree namespace: uberon def: "A submucosa that is part of a biliary tree [Automatically generated definition]." [OBOL:automatic] synonym: "biliary tract submucosa" EXACT [OBOL:automatic] synonym: "biliary tree submucosa" EXACT [OBOL:automatic] synonym: "submucosa of biliary tract" EXACT [OBOL:automatic] xref: FMA:18009 is_a: UBERON:0000009 ! submucosa is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001173 ! biliary tree relationship: part_of UBERON:0001173 ! biliary tree [Term] id: UBERON:0004939 name: submucosa of common bile duct namespace: uberon def: "A submucosa that is part of a common bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "common bile duct submucosa" EXACT [OBOL:automatic] synonym: "common bile ductal submucosa" EXACT [FMA:18011] synonym: "ductus choledochus (biliaris) submucosa" EXACT [OBOL:automatic] synonym: "submucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic] xref: FMA:18011 is_a: UBERON:0004938 ! submucosa of biliary tree intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001174 ! common bile duct relationship: part_of UBERON:0001174 ! common bile duct [Term] id: UBERON:0004940 name: submucosa of common hepatic duct namespace: uberon def: "A submucosa that is part of a common hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "common hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "common hepatic ductal submucosa" EXACT [FMA:18014] synonym: "hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "submucosa of hepatic duct" EXACT [OBOL:automatic] xref: FMA:18014 is_a: UBERON:0004938 ! submucosa of biliary tree intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001175 ! common hepatic duct relationship: part_of UBERON:0001175 ! common hepatic duct [Term] id: UBERON:0004941 name: submucosa of right hepatic duct namespace: uberon def: "A submucosa that is part of a right hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "right hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "right hepatic ductal submucosa" EXACT [FMA:18015] xref: FMA:18015 is_a: UBERON:0004938 ! submucosa of biliary tree intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001176 ! right hepatic duct relationship: part_of UBERON:0001176 ! right hepatic duct [Term] id: UBERON:0004942 name: submucosa of left hepatic duct namespace: uberon def: "A submucosa that is part of a left hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "left hepatic duct submucosa" EXACT [OBOL:automatic] synonym: "left hepatic ductal submucosa" EXACT [FMA:18017] xref: FMA:18017 is_a: UBERON:0004938 ! submucosa of biliary tree intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001177 ! left hepatic duct relationship: part_of UBERON:0001177 ! left hepatic duct [Term] id: UBERON:0004943 name: submucosa of urinary bladder namespace: uberon def: "The submucous layer of the wall of the urinary bladder." [BTO:0002117] subset: human_reference_atlas synonym: "bladder submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bladder" EXACT [OBOL:automatic] synonym: "submucous layer of urinary bladder" RELATED [BTO:0002117] synonym: "tela submucosa (vesica urinaria)" EXACT LATIN [FMA:15929, FMA:TA] synonym: "tela submucosa vesicae" EXACT LATIN [FMA:15929, FMA:TA] synonym: "tela submucosa vesicae urinariae" EXACT [BTO:0002117] synonym: "urinary bladder submucosa" EXACT [OBOL:automatic] xref: BTO:0002117 xref: EMAPA:32275 xref: FMA:15929 xref: SCTID:88384001 is_a: UBERON:0000009 ! submucosa is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001256 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0004945 name: submucosa of neck of urinary bladder namespace: uberon def: "A submucosa that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck submucosa" EXACT [OBOL:automatic] synonym: "neck of bladder submucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder submucosa" EXACT [OBOL:automatic] synonym: "submucosa of bladder neck" EXACT [OBOL:automatic] synonym: "submucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "submucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "submucosa of vesical neck" EXACT [OBOL:automatic] synonym: "urinary bladder neck submucosa" EXACT [OBOL:automatic] synonym: "vesical neck submucosa" EXACT [OBOL:automatic] xref: EMAPA:32276 xref: FMA:17851 is_a: UBERON:0004943 ! submucosa of urinary bladder intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001258 ! neck of urinary bladder relationship: part_of UBERON:0001258 ! neck of urinary bladder [Term] id: UBERON:0004952 name: submucosa of bronchiole namespace: uberon def: "A submucosa that is part of a bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole submucosa" EXACT [OBOL:automatic] xref: FMA:62775 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004777 ! respiratory system submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0002186 ! bronchiole relationship: part_of UBERON:0002186 ! bronchiole [Term] id: UBERON:0004980 name: mucosa of ureter namespace: uberon def: "A mucosa that is part of a ureter [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of ureter" EXACT [OBOL:automatic] synonym: "mucosal layer of ureter" EXACT [FMA:15894] synonym: "mucous membrane of ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of ureter" EXACT [OBOL:automatic] synonym: "tunica mucosa (ureter)" EXACT [FMA:15894] synonym: "tunica mucosa ureteris" EXACT LATIN [FMA:15894, FMA:TA] synonym: "ureter mucosa" EXACT [OBOL:automatic] synonym: "ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "ureter mucous membrane" EXACT [OBOL:automatic] synonym: "ureter organ mucosa" EXACT [OBOL:automatic] synonym: "ureteral mucosa" EXACT [FMA:15894] synonym: "ureteric mucosa" EXACT [FMA:15894] xref: FMA:15894 xref: galen:MucousMembraneOfUreter xref: SCTID:40476001 is_a: UBERON:0000344 ! mucosa is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0009916 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! wall of ureter [Term] id: UBERON:0004984 name: mucosa of seminal vesicle namespace: uberon def: "A mucosa that is part of a seminal vesicle [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of seminal gland" EXACT [OBOL:automatic] synonym: "mucosa of organ of seminal vesicle" EXACT [OBOL:automatic] synonym: "mucosa of seminal gland" EXACT [OBOL:automatic] synonym: "mucous membrane of seminal gland" EXACT [OBOL:automatic] synonym: "mucous membrane of seminal vesicle" EXACT [OBOL:automatic] synonym: "organ mucosa of seminal gland" EXACT [OBOL:automatic] synonym: "organ mucosa of seminal vesicle" EXACT [OBOL:automatic] synonym: "seminal gland mucosa" EXACT [OBOL:automatic] synonym: "seminal gland mucosa of organ" EXACT [OBOL:automatic] synonym: "seminal gland mucous membrane" EXACT [OBOL:automatic] synonym: "seminal gland organ mucosa" EXACT [OBOL:automatic] synonym: "seminal vesicle mucosa" EXACT [OBOL:automatic] synonym: "seminal vesicle mucosa of organ" EXACT [OBOL:automatic] synonym: "seminal vesicle mucous membrane" EXACT [OBOL:automatic] synonym: "seminal vesicle organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa glandulae vesiculosae" EXACT LATIN [FMA:19405, FMA:TA] xref: FMA:19405 xref: SCTID:252260007 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0019042 ! reproductive system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: part_of UBERON:0000998 ! seminal vesicle [Term] id: UBERON:0004985 name: mucosa of ejaculatory duct namespace: uberon def: "A mucosa that is part of a ejaculatory duct [Automatically generated definition]." [OBOL:automatic] synonym: "ejaculatory duct mucosa" EXACT [OBOL:automatic] synonym: "ejaculatory duct mucosa of organ" EXACT [OBOL:automatic] synonym: "ejaculatory duct mucous membrane" EXACT [OBOL:automatic] synonym: "ejaculatory duct organ mucosa" EXACT [OBOL:automatic] synonym: "ejaculatory ductal mucosa" EXACT [FMA:19373] synonym: "mucosa of organ of ejaculatory duct" EXACT [OBOL:automatic] synonym: "mucous membrane of ejaculatory duct" EXACT [OBOL:automatic] synonym: "organ mucosa of ejaculatory duct" EXACT [OBOL:automatic] xref: FMA:19373 is_a: UBERON:0019042 ! reproductive system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000999 ! ejaculatory duct relationship: part_of UBERON:0000999 ! ejaculatory duct [Term] id: UBERON:0004986 name: mucosa of deferent duct namespace: uberon def: "A mucosa that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] synonym: "deferent duct mucosa" EXACT [OBOL:automatic] synonym: "deferent duct mucosa of organ" EXACT [OBOL:automatic] synonym: "deferent duct mucous membrane" EXACT [OBOL:automatic] synonym: "deferent duct organ mucosa" EXACT [OBOL:automatic] synonym: "deferent ductal mucosa" EXACT [FMA:19240] synonym: "ductus deferens mucosa" EXACT [OBOL:automatic] synonym: "ductus deferens mucosa of organ" EXACT [OBOL:automatic] synonym: "ductus deferens mucous membrane" EXACT [OBOL:automatic] synonym: "ductus deferens organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of ductus deferens" EXACT [OBOL:automatic] synonym: "mucosa of organ of deferent duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of ductus deferens" EXACT [OBOL:automatic] synonym: "mucosa of organ of sperm duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of vas deferen" EXACT [OBOL:automatic] synonym: "mucosa of organ of vas deferens" EXACT [OBOL:automatic] synonym: "mucosa of sperm duct" EXACT [OBOL:automatic] synonym: "mucosa of vas deferen" EXACT [OBOL:automatic] synonym: "mucosa of vas deferens" EXACT [OBOL:automatic] synonym: "mucous membrane of deferent duct" EXACT [OBOL:automatic] synonym: "mucous membrane of ductus deferens" EXACT [OBOL:automatic] synonym: "mucous membrane of sperm duct" EXACT [OBOL:automatic] synonym: "mucous membrane of vas deferen" EXACT [OBOL:automatic] synonym: "mucous membrane of vas deferens" EXACT [OBOL:automatic] synonym: "organ mucosa of deferent duct" EXACT [OBOL:automatic] synonym: "organ mucosa of ductus deferens" EXACT [OBOL:automatic] synonym: "organ mucosa of sperm duct" EXACT [OBOL:automatic] synonym: "organ mucosa of vas deferen" EXACT [OBOL:automatic] synonym: "organ mucosa of vas deferens" EXACT [OBOL:automatic] synonym: "sperm duct mucosa" EXACT [OBOL:automatic] synonym: "sperm duct mucosa of organ" EXACT [OBOL:automatic] synonym: "sperm duct mucous membrane" EXACT [OBOL:automatic] synonym: "sperm duct organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa (ductus deferens)" EXACT [FMA:19240] synonym: "tunica mucosa ductus deferentis" EXACT LATIN [FMA:19240, FMA:TA] synonym: "vas deferen mucosa" EXACT [OBOL:automatic] synonym: "vas deferen mucosa of organ" EXACT [OBOL:automatic] synonym: "vas deferen mucous membrane" EXACT [OBOL:automatic] synonym: "vas deferen organ mucosa" EXACT [OBOL:automatic] synonym: "vas deferens mucosa" EXACT [OBOL:automatic] synonym: "vas deferens mucosa of organ" EXACT [OBOL:automatic] synonym: "vas deferens mucous membrane" EXACT [OBOL:automatic] synonym: "vas deferens organ mucosa" EXACT [OBOL:automatic] xref: FMA:19240 xref: SCTID:299626000 is_a: UBERON:0019042 ! reproductive system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001000 ! vas deferens relationship: part_of UBERON:0001000 ! vas deferens [Term] id: UBERON:0004988 name: mucosa of cystic duct namespace: uberon def: "A mucosa that is part of a cystic duct [Automatically generated definition]." [OBOL:automatic] synonym: "cystic duct mucosa" EXACT [OBOL:automatic] synonym: "cystic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "cystic duct mucous membrane" EXACT [OBOL:automatic] synonym: "cystic duct organ mucosa" EXACT [OBOL:automatic] synonym: "cystic ductal mucosa" EXACT [FMA:14690] synonym: "mucosa of organ of cystic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of cystic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of cystic duct" EXACT [OBOL:automatic] xref: FMA:14690 is_a: UBERON:0004999 ! mucosa of biliary tree intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001152 ! cystic duct relationship: part_of UBERON:0001152 ! cystic duct [Term] id: UBERON:0004993 name: mucosa of sigmoid colon namespace: uberon def: "A mucosa that is part of a sigmoid colon [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of sigmoid colon" EXACT [OBOL:automatic] synonym: "mucous membrane of sigmoid colon" EXACT [OBOL:automatic] synonym: "organ mucosa of sigmoid colon" EXACT [OBOL:automatic] synonym: "sigmoid colon mucosa" EXACT [OBOL:automatic] synonym: "sigmoid colon mucosa of organ" EXACT [OBOL:automatic] synonym: "sigmoid colon mucous membrane" EXACT [OBOL:automatic] synonym: "sigmoid colon organ mucosa" EXACT [OBOL:automatic] xref: FMA:15026 is_a: UBERON:0000317 ! colonic mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001159 ! sigmoid colon relationship: part_of UBERON:0001159 ! sigmoid colon [Term] id: UBERON:0004995 name: mucosa of body of stomach namespace: uberon def: "A mucosa that is part of a body of stomach [Automatically generated definition]." [OBOL:automatic] synonym: "body of stomach mucosa" EXACT [OBOL:automatic] synonym: "body of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "body of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "body of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) mucosa" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) mucosa of organ" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) mucous membrane" EXACT [OBOL:automatic] synonym: "corpus gastricum (ventriculare) organ mucosa" EXACT [OBOL:automatic] synonym: "gastric body mucosa" EXACT [OBOL:automatic] synonym: "gastric body mucosa of organ" EXACT [OBOL:automatic] synonym: "gastric body mucous membrane" EXACT [OBOL:automatic] synonym: "gastric body organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "mucosa of gastric body" EXACT [OBOL:automatic] synonym: "mucosa of organ of body of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "mucosa of organ of gastric body" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach body" EXACT [OBOL:automatic] synonym: "mucosa of stomach body" EXACT [OBOL:automatic] synonym: "mucous membrane of body of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "mucous membrane of gastric body" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach body" EXACT [OBOL:automatic] synonym: "organ mucosa of body of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of corpus gastricum (ventriculare)" EXACT [OBOL:automatic] synonym: "organ mucosa of gastric body" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach body" EXACT [OBOL:automatic] synonym: "stomach body mucosa" EXACT [OBOL:automatic] synonym: "stomach body mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach body mucous membrane" EXACT [OBOL:automatic] synonym: "stomach body organ mucosa" EXACT [OBOL:automatic] xref: FMA:17054 is_a: UBERON:0001199 ! mucosa of stomach intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001161 ! body of stomach relationship: part_of UBERON:0001161 ! body of stomach [Term] id: UBERON:0004997 name: mucosa of pyloric antrum namespace: uberon def: "A mucosa that is part of a pyloric antrum [Automatically generated definition]." [OBOL:automatic] synonym: "antral mucosa" EXACT [BTO:0004107] synonym: "antrum of stomach mucosa" EXACT [OBOL:automatic] synonym: "antrum of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "antrum of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "antrum of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "gastric antrum mucosa" RELATED [BTO:0004107] synonym: "mucosa of antrum of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of antrum of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of pyloric antrum" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "mucosa of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "mucous membrane of antrum of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of pyloric antrum" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "organ mucosa of antrum of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of pyloric antrum" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach pyloric antrum" EXACT [OBOL:automatic] synonym: "pyloric antrum mucosa" EXACT [OBOL:automatic] synonym: "pyloric antrum mucosa of organ" EXACT [OBOL:automatic] synonym: "pyloric antrum mucous membrane" EXACT [OBOL:automatic] synonym: "pyloric antrum organ mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum mucous membrane" EXACT [OBOL:automatic] synonym: "stomach pyloric antrum organ mucosa" EXACT [OBOL:automatic] xref: BTO:0004107 xref: FMA:17055 is_a: UBERON:0004998 ! mucosa of pylorus intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001165 ! pyloric antrum relationship: part_of UBERON:0001165 ! pyloric antrum relationship: part_of UBERON:0004998 {source="BTO"} ! mucosa of pylorus [Term] id: UBERON:0004998 name: mucosa of pylorus namespace: uberon def: "A mucosa that is part of a pylorus [Automatically generated definition]." [OBOL:automatic] synonym: "antropyloric mucosa" RELATED [BTO:0002984] synonym: "mucosa of organ of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "mucosa of organ of pylorus" EXACT [OBOL:automatic] synonym: "mucosa of organ of stomach pyloric region" EXACT [OBOL:automatic] synonym: "mucosa of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "mucosa of stomach pyloric region" EXACT [OBOL:automatic] synonym: "mucous membrane of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "mucous membrane of pylorus" EXACT [OBOL:automatic] synonym: "mucous membrane of stomach pyloric region" EXACT [OBOL:automatic] synonym: "organ mucosa of pyloric part of stomach" EXACT [OBOL:automatic] synonym: "organ mucosa of pylorus" EXACT [OBOL:automatic] synonym: "organ mucosa of stomach pyloric region" EXACT [OBOL:automatic] synonym: "pyloric part of stomach mucosa" EXACT [OBOL:automatic] synonym: "pyloric part of stomach mucosa of organ" EXACT [OBOL:automatic] synonym: "pyloric part of stomach mucous membrane" EXACT [OBOL:automatic] synonym: "pyloric part of stomach organ mucosa" EXACT [OBOL:automatic] synonym: "pylorus mucosa" EXACT [OBOL:automatic] synonym: "pylorus mucosa of organ" EXACT [OBOL:automatic] synonym: "pylorus mucous membrane" EXACT [OBOL:automatic] synonym: "pylorus organ mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric region mucosa" EXACT [OBOL:automatic] synonym: "stomach pyloric region mucosa of organ" EXACT [OBOL:automatic] synonym: "stomach pyloric region mucous membrane" EXACT [OBOL:automatic] synonym: "stomach pyloric region organ mucosa" EXACT [OBOL:automatic] xref: BTO:0004110 xref: EMAPA:27199 xref: FMA:17461 is_a: UBERON:0001199 ! mucosa of stomach intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001166 ! pylorus relationship: part_of UBERON:0001166 ! pylorus [Term] id: UBERON:0004999 name: mucosa of biliary tree namespace: uberon def: "A mucosa that is part of a biliary tree [Automatically generated definition]." [OBOL:automatic] synonym: "biliary tract mucosa" EXACT [OBOL:automatic] synonym: "biliary tract mucosa of organ" EXACT [OBOL:automatic] synonym: "biliary tract mucous membrane" EXACT [OBOL:automatic] synonym: "biliary tract organ mucosa" EXACT [OBOL:automatic] synonym: "biliary tree mucosa" EXACT [OBOL:automatic] synonym: "biliary tree mucosa of organ" EXACT [OBOL:automatic] synonym: "biliary tree mucous membrane" EXACT [OBOL:automatic] synonym: "biliary tree organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of biliary tract" EXACT [OBOL:automatic] synonym: "mucosa of organ of biliary tract" EXACT [OBOL:automatic] synonym: "mucosa of organ of biliary tree" EXACT [OBOL:automatic] synonym: "mucous membrane of biliary tract" EXACT [OBOL:automatic] synonym: "mucous membrane of biliary tree" EXACT [OBOL:automatic] synonym: "organ mucosa of biliary tract" EXACT [OBOL:automatic] synonym: "organ mucosa of biliary tree" EXACT [OBOL:automatic] xref: FMA:14695 is_a: UBERON:0000344 ! mucosa is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001173 ! biliary tree relationship: part_of UBERON:0001173 ! biliary tree [Term] id: UBERON:0005000 name: mucosa of common bile duct namespace: uberon def: "A mucosa that is part of a common bile duct [Automatically generated definition]." [OBOL:automatic] synonym: "common bile duct mucosa" EXACT [OBOL:automatic] synonym: "common bile duct mucosa of organ" EXACT [OBOL:automatic] synonym: "common bile duct mucous membrane" EXACT [OBOL:automatic] synonym: "common bile duct organ mucosa" EXACT [OBOL:automatic] synonym: "common bile ductal mucosa" EXACT [FMA:14688] synonym: "ductus choledochus (biliaris) mucosa" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) mucosa of organ" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) mucous membrane" EXACT [OBOL:automatic] synonym: "ductus choledochus (biliaris) organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "mucosa of organ of common bile duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "mucous membrane of common bile duct" EXACT [OBOL:automatic] synonym: "mucous membrane of ductus choledochus (biliaris)" EXACT [OBOL:automatic] synonym: "organ mucosa of common bile duct" EXACT [OBOL:automatic] synonym: "organ mucosa of ductus choledochus (biliaris)" EXACT [OBOL:automatic] xref: FMA:14688 is_a: UBERON:0004999 ! mucosa of biliary tree intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001174 ! common bile duct relationship: part_of UBERON:0001174 ! common bile duct [Term] id: UBERON:0005001 name: mucosa of common hepatic duct namespace: uberon def: "A mucosa that is part of a common hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "common hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "common hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "common hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "common hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "common hepatic ductal mucosa" EXACT [FMA:14691] synonym: "hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of hepatic duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of common hepatic duct" EXACT [OBOL:automatic] synonym: "mucosa of organ of hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of common hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of common hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of hepatic duct" EXACT [OBOL:automatic] xref: FMA:14691 is_a: UBERON:0004999 ! mucosa of biliary tree intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001175 ! common hepatic duct relationship: part_of UBERON:0001175 ! common hepatic duct [Term] id: UBERON:0005002 name: mucosa of right hepatic duct namespace: uberon def: "A mucosa that is part of a right hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of right hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of right hepatic duct" EXACT [OBOL:automatic] synonym: "right hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "right hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "right hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "right hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "right hepatic ductal mucosa" EXACT [FMA:14692] xref: FMA:14692 is_a: UBERON:0004999 ! mucosa of biliary tree intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001176 ! right hepatic duct relationship: part_of UBERON:0001176 ! right hepatic duct [Term] id: UBERON:0005003 name: mucosa of left hepatic duct namespace: uberon def: "A mucosa that is part of a left hepatic duct [Automatically generated definition]." [OBOL:automatic] synonym: "left hepatic duct mucosa" EXACT [OBOL:automatic] synonym: "left hepatic duct mucosa of organ" EXACT [OBOL:automatic] synonym: "left hepatic duct mucous membrane" EXACT [OBOL:automatic] synonym: "left hepatic duct organ mucosa" EXACT [OBOL:automatic] synonym: "left hepatic ductal mucosa" EXACT [FMA:14693] synonym: "mucosa of organ of left hepatic duct" EXACT [OBOL:automatic] synonym: "mucous membrane of left hepatic duct" EXACT [OBOL:automatic] synonym: "organ mucosa of left hepatic duct" EXACT [OBOL:automatic] xref: FMA:14693 is_a: UBERON:0004999 ! mucosa of biliary tree intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001177 ! left hepatic duct relationship: part_of UBERON:0001177 ! left hepatic duct [Term] id: UBERON:0005004 name: mucosa of right ureter namespace: uberon def: "A mucosa that is part of a right ureter [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of right ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of right ureter" EXACT [OBOL:automatic] synonym: "right ureter mucosa" EXACT [OBOL:automatic] synonym: "right ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "right ureter mucous membrane" EXACT [OBOL:automatic] synonym: "right ureter organ mucosa" EXACT [OBOL:automatic] synonym: "right ureteral mucosa" EXACT [FMA:17806] xref: FMA:17806 is_a: UBERON:0004980 ! mucosa of ureter intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001222 ! right ureter relationship: part_of UBERON:0001222 ! right ureter [Term] id: UBERON:0005005 name: mucosa of left ureter namespace: uberon def: "A mucosa that is part of a left ureter [Automatically generated definition]." [OBOL:automatic] subset: human_reference_atlas synonym: "left ureter mucosa" EXACT [OBOL:automatic] synonym: "left ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "left ureter mucous membrane" EXACT [OBOL:automatic] synonym: "left ureter organ mucosa" EXACT [OBOL:automatic] synonym: "left ureteral mucosa" EXACT [FMA:17807] synonym: "mucosa of organ of left ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of left ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of left ureter" EXACT [OBOL:automatic] xref: FMA:17807 is_a: UBERON:0004980 ! mucosa of ureter intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001223 ! left ureter relationship: part_of UBERON:0001223 ! left ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0005006 name: mucosa of renal pelvis namespace: uberon def: "A mucosa that is part of a renal pelvis [Automatically generated definition]." [OBOL:automatic] synonym: "kidney pelvis mucosa" EXACT [OBOL:automatic] synonym: "kidney pelvis mucosa of organ" EXACT [OBOL:automatic] synonym: "kidney pelvis mucous membrane" EXACT [OBOL:automatic] synonym: "kidney pelvis organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucosa of organ of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucosa of organ of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucosa of organ of renal pelvis" EXACT [OBOL:automatic] synonym: "mucosa of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of kidney pelvis" EXACT [OBOL:automatic] synonym: "mucous membrane of pelvis of ureter" EXACT [OBOL:automatic] synonym: "mucous membrane of renal pelvis" EXACT [OBOL:automatic] synonym: "organ mucosa of kidney pelvis" EXACT [OBOL:automatic] synonym: "organ mucosa of pelvis of ureter" EXACT [OBOL:automatic] synonym: "organ mucosa of renal pelvis" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucosa" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucosa of organ" EXACT [OBOL:automatic] synonym: "pelvis of ureter mucous membrane" EXACT [OBOL:automatic] synonym: "pelvis of ureter organ mucosa" EXACT [OBOL:automatic] synonym: "renal pelvic mucosa" EXACT [FMA:17931] synonym: "renal pelvis mucosa" EXACT [OBOL:automatic] synonym: "renal pelvis mucosa of organ" EXACT [OBOL:automatic] synonym: "renal pelvis mucous membrane" EXACT [OBOL:automatic] synonym: "renal pelvis organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa pelvis renalis" EXACT LATIN [FMA:17931, FMA:TA] xref: FMA:17931 xref: SCTID:243482002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001224 ! renal pelvis relationship: part_of UBERON:0001224 ! renal pelvis [Term] id: UBERON:0005010 name: mucosa of neck of urinary bladder namespace: uberon def: "A mucosa that is part of a neck of urinary bladder [Automatically generated definition]." [OBOL:automatic] synonym: "bladder neck mucosa" EXACT [OBOL:automatic] synonym: "bladder neck mucosa of organ" EXACT [OBOL:automatic] synonym: "bladder neck mucous membrane" EXACT [OBOL:automatic] synonym: "bladder neck organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of organ of neck of bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of organ of vesical neck" EXACT [OBOL:automatic] synonym: "mucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucosa of vesical neck" EXACT [OBOL:automatic] synonym: "mucous membrane of bladder neck" EXACT [OBOL:automatic] synonym: "mucous membrane of neck of bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of urinary bladder neck" EXACT [OBOL:automatic] synonym: "mucous membrane of vesical neck" EXACT [OBOL:automatic] synonym: "neck of bladder mucosa" EXACT [OBOL:automatic] synonym: "neck of bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "neck of bladder mucous membrane" EXACT [OBOL:automatic] synonym: "neck of bladder organ mucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucosa" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "neck of urinary bladder mucous membrane" EXACT [OBOL:automatic] synonym: "neck of urinary bladder organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of bladder neck" EXACT [OBOL:automatic] synonym: "organ mucosa of neck of bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of neck of urinary bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of urinary bladder neck" EXACT [OBOL:automatic] synonym: "organ mucosa of vesical neck" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucosa" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucosa of organ" EXACT [OBOL:automatic] synonym: "urinary bladder neck mucous membrane" EXACT [OBOL:automatic] synonym: "vesical neck mucosa" EXACT [OBOL:automatic] synonym: "vesical neck mucosa of organ" EXACT [OBOL:automatic] synonym: "vesical neck mucous membrane" EXACT [OBOL:automatic] synonym: "vesical neck organ mucosa" EXACT [OBOL:automatic] xref: FMA:17846 is_a: UBERON:0001259 ! mucosa of urinary bladder intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001258 ! neck of urinary bladder relationship: part_of UBERON:0001258 ! neck of urinary bladder [Term] id: UBERON:0005011 name: mucosa of right uterine tube namespace: uberon def: "A mucosa that is part of a right uterine tube [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of right fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of right oviduct" EXACT [OBOL:automatic] synonym: "mucosa of organ of right uterine tube" EXACT [OBOL:automatic] synonym: "mucosa of right fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of right oviduct" EXACT [OBOL:automatic] synonym: "mucous membrane of right fallopian tube" EXACT [OBOL:automatic] synonym: "mucous membrane of right oviduct" EXACT [OBOL:automatic] synonym: "mucous membrane of right uterine tube" EXACT [OBOL:automatic] synonym: "organ mucosa of right fallopian tube" EXACT [OBOL:automatic] synonym: "organ mucosa of right oviduct" EXACT [OBOL:automatic] synonym: "organ mucosa of right uterine tube" EXACT [OBOL:automatic] synonym: "right fallopian tube mucosa" EXACT [OBOL:automatic] synonym: "right fallopian tube mucosa of organ" EXACT [OBOL:automatic] synonym: "right fallopian tube mucous membrane" EXACT [OBOL:automatic] synonym: "right fallopian tube organ mucosa" EXACT [OBOL:automatic] synonym: "right oviduct mucosa" EXACT [OBOL:automatic] synonym: "right oviduct mucosa of organ" EXACT [OBOL:automatic] synonym: "right oviduct mucous membrane" EXACT [OBOL:automatic] synonym: "right oviduct organ mucosa" EXACT [OBOL:automatic] synonym: "right uterine tube mucosa" EXACT [OBOL:automatic] synonym: "right uterine tube mucosa of organ" EXACT [OBOL:automatic] synonym: "right uterine tube mucous membrane" EXACT [OBOL:automatic] synonym: "right uterine tube organ mucosa" EXACT [OBOL:automatic] xref: FMA:18452 is_a: UBERON:0005048 ! mucosa of uterine tube intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001302 ! right uterine tube relationship: part_of UBERON:0001302 ! right uterine tube [Term] id: UBERON:0005012 name: mucosa of left uterine tube namespace: uberon def: "A mucosa that is part of a left uterine tube [Automatically generated definition]." [OBOL:automatic] synonym: "left fallopian tube mucosa" EXACT [OBOL:automatic] synonym: "left fallopian tube mucosa of organ" EXACT [OBOL:automatic] synonym: "left fallopian tube mucous membrane" EXACT [OBOL:automatic] synonym: "left fallopian tube organ mucosa" EXACT [OBOL:automatic] synonym: "left oviduct mucosa" EXACT [OBOL:automatic] synonym: "left oviduct mucosa of organ" EXACT [OBOL:automatic] synonym: "left oviduct mucous membrane" EXACT [OBOL:automatic] synonym: "left oviduct organ mucosa" EXACT [OBOL:automatic] synonym: "left uterine tube mucosa" EXACT [OBOL:automatic] synonym: "left uterine tube mucosa of organ" EXACT [OBOL:automatic] synonym: "left uterine tube mucous membrane" EXACT [OBOL:automatic] synonym: "left uterine tube organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of left fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of left oviduct" EXACT [OBOL:automatic] synonym: "mucosa of organ of left fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of left oviduct" EXACT [OBOL:automatic] synonym: "mucosa of organ of left uterine tube" EXACT [OBOL:automatic] synonym: "mucous membrane of left fallopian tube" EXACT [OBOL:automatic] synonym: "mucous membrane of left oviduct" EXACT [OBOL:automatic] synonym: "mucous membrane of left uterine tube" EXACT [OBOL:automatic] synonym: "organ mucosa of left fallopian tube" EXACT [OBOL:automatic] synonym: "organ mucosa of left oviduct" EXACT [OBOL:automatic] synonym: "organ mucosa of left uterine tube" EXACT [OBOL:automatic] xref: FMA:18453 is_a: UBERON:0005048 ! mucosa of uterine tube intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001303 ! left uterine tube relationship: part_of UBERON:0001303 ! left uterine tube [Term] id: UBERON:0005013 name: mucosa of male urethra namespace: uberon def: "A mucosa that is part of a male urethra [Automatically generated definition]." [OBOL:automatic] synonym: "male urethra mucosa" EXACT [OBOL:automatic] synonym: "male urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "male urethra mucous membrane" EXACT [OBOL:automatic] synonym: "male urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of male urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of male urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of male urethra" EXACT [OBOL:automatic] xref: FMA:239937 is_a: UBERON:0012299 ! mucosa of urethra intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001333 ! male urethra relationship: part_of UBERON:0001333 ! male urethra [Term] id: UBERON:0005014 name: mucosa of female urethra namespace: uberon def: "A mucosa that is part of a female urethra [Automatically generated definition]." [OBOL:automatic] synonym: "female urethra mucosa" EXACT [OBOL:automatic] synonym: "female urethra mucosa of organ" EXACT [OBOL:automatic] synonym: "female urethra mucous membrane" EXACT [OBOL:automatic] synonym: "female urethra organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of female urethra" EXACT [OBOL:automatic] synonym: "mucous membrane of female urethra" EXACT [OBOL:automatic] synonym: "organ mucosa of female urethra" EXACT [OBOL:automatic] xref: FMA:239940 is_a: UBERON:0012299 ! mucosa of urethra intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001334 ! female urethra relationship: part_of UBERON:0001334 ! female urethra [Term] id: UBERON:0005019 name: mucosa of palate namespace: uberon def: "A mucosa that is part of a palate [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of oral roof" EXACT [OBOL:automatic] synonym: "mucosa of organ of oral roof" EXACT [OBOL:automatic] synonym: "mucosa of organ of palate" EXACT [OBOL:automatic] synonym: "mucosa of organ of roof of mouth" EXACT [OBOL:automatic] synonym: "mucosa of roof of mouth" EXACT [OBOL:automatic] synonym: "mucous membrane of oral roof" EXACT [OBOL:automatic] synonym: "mucous membrane of palate" EXACT [OBOL:automatic] synonym: "mucous membrane of roof of mouth" EXACT [OBOL:automatic] synonym: "oral roof mucosa" EXACT [OBOL:automatic] synonym: "oral roof mucosa of organ" EXACT [OBOL:automatic] synonym: "oral roof mucous membrane" EXACT [OBOL:automatic] synonym: "oral roof organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of oral roof" EXACT [OBOL:automatic] synonym: "organ mucosa of palate" EXACT [OBOL:automatic] synonym: "organ mucosa of roof of mouth" EXACT [OBOL:automatic] synonym: "palate mucosa" EXACT [OBOL:automatic] synonym: "palate mucosa of organ" EXACT [OBOL:automatic] synonym: "palate mucous membrane" EXACT [OBOL:automatic] synonym: "palate organ mucosa" EXACT [OBOL:automatic] synonym: "roof of mouth mucosa" EXACT [OBOL:automatic] synonym: "roof of mouth mucosa of organ" EXACT [OBOL:automatic] synonym: "roof of mouth mucous membrane" EXACT [OBOL:automatic] synonym: "roof of mouth organ mucosa" EXACT [OBOL:automatic] xref: FMA:59765 is_a: UBERON:0003729 ! mouth mucosa is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001716 ! secondary palate relationship: part_of UBERON:0001716 ! secondary palate [Term] id: UBERON:0005020 name: mucosa of tongue namespace: uberon def: "A mucosa that is part of a tongue [Automatically generated definition]." [OBOL:automatic] subset: efo_slim synonym: "lingual mucosa" EXACT [FMA:54807] synonym: "mucosa of organ of tongue" EXACT [OBOL:automatic] synonym: "mucous membrane of tongue" EXACT [OBOL:automatic] synonym: "organ mucosa of tongue" EXACT [OBOL:automatic] synonym: "tongue mucosa" EXACT [OBOL:automatic] synonym: "tongue mucosa of organ" EXACT [OBOL:automatic] synonym: "tongue mucous membrane" EXACT [OBOL:automatic] synonym: "tongue organ mucosa" EXACT [OBOL:automatic] synonym: "tunica mucosa linguae" EXACT LATIN [FMA:54807, FMA:TA] xref: EFO:0002553 xref: FMA:54807 xref: SCTID:362092002 is_a: UBERON:0003729 ! mouth mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0005022 name: mucosa of nasopharynx namespace: uberon def: "A mucosa that is part of a nasopharynx [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of nasopharynx" EXACT [OBOL:automatic] synonym: "mucosa of organ of rhinopharynx" EXACT [OBOL:automatic] synonym: "mucosa of rhinopharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of nasopharynx" EXACT [OBOL:automatic] synonym: "mucous membrane of rhinopharynx" EXACT [OBOL:automatic] synonym: "nasal part of pharynx mucosa" EXACT [OBOL:automatic] synonym: "nasal part of pharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "nasal part of pharynx mucous membrane" EXACT [OBOL:automatic] synonym: "nasal part of pharynx organ mucosa" EXACT [OBOL:automatic] synonym: "nasopharynx mucosa" EXACT [OBOL:automatic] synonym: "nasopharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "nasopharynx mucous membrane" EXACT [OBOL:automatic] synonym: "nasopharynx organ mucosa" EXACT [OBOL:automatic] synonym: "organ mucosa of nasal part of pharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of nasopharynx" EXACT [OBOL:automatic] synonym: "organ mucosa of rhinopharynx" EXACT [OBOL:automatic] synonym: "rhinopharynx mucosa" EXACT [OBOL:automatic] synonym: "rhinopharynx mucosa of organ" EXACT [OBOL:automatic] synonym: "rhinopharynx mucous membrane" EXACT [OBOL:automatic] synonym: "rhinopharynx organ mucosa" EXACT [OBOL:automatic] xref: FMA:54971 xref: SCTID:361938001 is_a: UBERON:0000355 ! pharyngeal mucosa is_a: UBERON:0000379 ! tracheal mucosa is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001728 ! nasopharynx [Term] id: UBERON:0005026 name: mucosa of middle ear namespace: uberon def: "A mucosa that is part of a middle ear [Automatically generated definition]." [OBOL:automatic] synonym: "middle ear mucosa" EXACT [OBOL:automatic] synonym: "middle ear mucosa of organ" EXACT [OBOL:automatic] synonym: "middle ear mucous membrane" EXACT [OBOL:automatic] synonym: "middle ear organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of middle ear" EXACT [OBOL:automatic] synonym: "mucosa of tympanic cavity" EXACT [FMA:59663] synonym: "mucous membrane of middle ear" EXACT [OBOL:automatic] synonym: "organ mucosa of middle ear" EXACT [OBOL:automatic] synonym: "tunica mucosa cavitatis tympanicae" EXACT LATIN [FMA:59663, FMA:TA] xref: CALOHA:TS-0631 xref: FMA:59663 is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001756 ! middle ear relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0005031 name: mucosa of upper lip namespace: uberon def: "A mucosa that is part of a upper lip [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of organ of upper lip" EXACT [OBOL:automatic] synonym: "mucous membrane of upper lip" EXACT [OBOL:automatic] synonym: "organ mucosa of upper lip" EXACT [OBOL:automatic] synonym: "upper labial mucosa" EXACT [UBERON:cjm] synonym: "upper lip mucosa" EXACT [OBOL:automatic] synonym: "upper lip mucosa of organ" EXACT [OBOL:automatic] synonym: "upper lip mucous membrane" EXACT [OBOL:automatic] synonym: "upper lip organ mucosa" EXACT [OBOL:automatic] xref: FMA:59832 xref: NCIT:C12224 xref: SCTID:362088009 xref: UMLS:C0226933 {source="ncithesaurus:Mucosa_of_the_Upper_Lip"} is_a: UBERON:0036294 ! mucosa of lip intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001834 ! upper lip relationship: part_of UBERON:0001834 ! upper lip [Term] id: UBERON:0005032 name: mucosa of lower lip namespace: uberon def: "A mucosa that is part of a lower lip [Automatically generated definition]." [OBOL:automatic] synonym: "lower labial mucosa" EXACT [UBERON:cjm] synonym: "lower lip mucosa" EXACT [OBOL:automatic] synonym: "lower lip mucosa of organ" EXACT [OBOL:automatic] synonym: "lower lip mucous membrane" EXACT [OBOL:automatic] synonym: "lower lip organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of lower lip" EXACT [OBOL:automatic] synonym: "mucous membrane of lower lip" EXACT [OBOL:automatic] synonym: "organ mucosa of lower lip" EXACT [OBOL:automatic] xref: FMA:59833 xref: NCIT:C12225 xref: SCTID:362089001 xref: UMLS:C0226939 {source="ncithesaurus:Mucosa_of_the_Lower_Lip"} is_a: UBERON:0036294 ! mucosa of lip intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001835 ! lower lip relationship: part_of UBERON:0001835 ! lower lip [Term] id: UBERON:0005033 name: mucosa of gallbladder namespace: uberon def: "A mucosa that is part of a gallbladder [Automatically generated definition]." [OBOL:automatic] synonym: "gall bladder mucosa" EXACT [OBOL:automatic] synonym: "gall bladder mucosa of organ" EXACT [OBOL:automatic] synonym: "gall bladder mucous membrane" EXACT [OBOL:automatic] synonym: "gall bladder organ mucosa" EXACT [OBOL:automatic] synonym: "gallbladder mucosa" EXACT [OBOL:automatic] synonym: "gallbladder mucosa of organ" EXACT [OBOL:automatic] synonym: "gallbladder mucous membrane" EXACT [OBOL:automatic] synonym: "gallbladder organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of gall bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of gall bladder" EXACT [OBOL:automatic] synonym: "mucosa of organ of gallbladder" EXACT [OBOL:automatic] synonym: "mucous membrane of gall bladder" EXACT [OBOL:automatic] synonym: "mucous membrane of gallbladder" EXACT [OBOL:automatic] synonym: "organ mucosa of gall bladder" EXACT [OBOL:automatic] synonym: "organ mucosa of gallbladder" EXACT [OBOL:automatic] synonym: "tunica mucosa (vesica biliaris)" EXACT [FMA:14662] synonym: "tunica mucosa vesicae biliaris" EXACT LATIN [FMA:14662, FMA:TA] xref: FMA:14662 xref: SCTID:362196002 is_a: UBERON:0000344 ! mucosa is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: UBERON:0005039 name: mucosa of bronchiole namespace: uberon def: "A mucosa that is part of a bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiole mucosa" EXACT [OBOL:automatic] synonym: "bronchiole mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchiole mucous membrane" EXACT [OBOL:automatic] synonym: "bronchiole organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchiole" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchiole" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchiole" EXACT [OBOL:automatic] xref: FMA:62774 xref: SCTID:10887006 is_a: UBERON:0000379 ! tracheal mucosa is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002186 ! bronchiole relationship: part_of UBERON:0002186 ! bronchiole [Term] id: UBERON:0005040 name: mucosa of terminal bronchiole namespace: uberon def: "A mucosa that is part of a terminal bronchiole [Automatically generated definition]." [OBOL:automatic] synonym: "bronchiolus terminalis mucosa" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis mucosa of organ" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis mucous membrane" EXACT [OBOL:automatic] synonym: "bronchiolus terminalis organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "mucosa of organ of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "mucosa of organ of terminal bronchiole" EXACT [OBOL:automatic] synonym: "mucous membrane of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "mucous membrane of terminal bronchiole" EXACT [OBOL:automatic] synonym: "organ mucosa of bronchiolus terminalis" EXACT [OBOL:automatic] synonym: "organ mucosa of terminal bronchiole" EXACT [OBOL:automatic] synonym: "terminal bronchiole mucosa" EXACT [OBOL:automatic] synonym: "terminal bronchiole mucosa of organ" EXACT [OBOL:automatic] synonym: "terminal bronchiole mucous membrane" EXACT [OBOL:automatic] synonym: "terminal bronchiole organ mucosa" EXACT [OBOL:automatic] xref: FMA:263232 is_a: UBERON:0005039 ! mucosa of bronchiole intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0002187 ! terminal bronchiole relationship: part_of UBERON:0002187 ! terminal bronchiole [Term] id: UBERON:0005042 name: inner epithelial layer of tympanic membrane namespace: uberon def: "A portion of the tympanic cavity epithelium which makes up the outer (cuticular) layer of the tympanic membrane." [https://orcid.org/0000-0002-6601-2165, PMID:11237469] synonym: "mucosa of tympanic membrane" EXACT [FMA:56844] synonym: "mucous layer of tympanic membrane" EXACT [FMA:56844] synonym: "mucous stratum of tympanic membrane" EXACT [FMA:56844] synonym: "tympanic membrane external middle ear cavity epithelial component" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "tympanic membrane mucosa" EXACT [FMA:56844] xref: FMA:56844 xref: SCTID:36411006 is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0009647 ! tympanic membrane epithelium intersection_of: UBERON:0009647 ! tympanic membrane epithelium intersection_of: part_of UBERON:0010063 ! tympanic cavity epithelium relationship: part_of UBERON:0010063 ! tympanic cavity epithelium property_value: UBPROP:0000012 "in FMA this is classified as a mucosa" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0005046 name: mucosa of hard palate namespace: uberon def: "A mucosa that is part of a hard palate [Automatically generated definition]." [OBOL:automatic] synonym: "hard palate mucosa" EXACT [OBOL:accepted] synonym: "hard palate mucous membrane" EXACT [OBOL:automatic] synonym: "mucous membrane of hard palate" EXACT [OBOL:automatic] synonym: "organ mucosa of hard palate" EXACT [OBOL:automatic] xref: FMA:59783 xref: SCTID:245841005 is_a: UBERON:0005019 ! mucosa of palate intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0003216 ! hard palate relationship: part_of UBERON:0003216 ! hard palate [Term] id: UBERON:0005048 name: mucosa of uterine tube namespace: uberon def: "A mucosa that is part of a fallopian tube [Automatically generated definition]." [OBOL:automatic] synonym: "fallopian tube mucosa" EXACT [OBOL:automatic] synonym: "fallopian tube mucosa of organ" EXACT [OBOL:automatic] synonym: "fallopian tube mucous membrane" EXACT [OBOL:automatic] synonym: "fallopian tube organ mucosa" EXACT [OBOL:automatic] synonym: "mucosa of fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of fallopian tube" EXACT [OBOL:automatic] synonym: "mucosa of organ of uterine tube" EXACT [OBOL:automatic] synonym: "mucosa of oviduct" EXACT [FMA:18319] synonym: "mucous membrane of fallopian tube" EXACT [OBOL:automatic] synonym: "mucous membrane of uterine tube" EXACT [OBOL:automatic] synonym: "organ mucosa of fallopian tube" EXACT [OBOL:automatic] synonym: "organ mucosa of uterine tube" EXACT [OBOL:automatic] synonym: "tunica mucosa tubae uterinae" EXACT LATIN [FMA:18319, FMA:TA] synonym: "uterine tubal mucosa" EXACT [FMA:18319] synonym: "uterine tube mucosa" EXACT [OBOL:automatic] synonym: "uterine tube mucosa of organ" EXACT [OBOL:automatic] synonym: "uterine tube mucous membrane" EXACT [OBOL:automatic] synonym: "uterine tube organ mucosa" EXACT [OBOL:automatic] xref: FMA:18319 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0019042 ! reproductive system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: part_of UBERON:0003889 ! fallopian tube [Term] id: UBERON:0005049 name: mucosa of infundibulum of uterine tube namespace: uberon def: "A mucosa that is part of a uterine tube infundibulum [Automatically generated definition]." [OBOL:automatic] synonym: "mucosa of infundibulum of fallopian tube" EXACT [FMA:18357] synonym: "mucosa of infundibulum of oviduct" EXACT [FMA:18357] synonym: "mucosa of organ of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "mucosa of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "mucous membrane of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "organ mucosa of uterine tube infundibulum" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum mucosa" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum mucosa of organ" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum mucous membrane" EXACT [OBOL:automatic] synonym: "uterine tube infundibulum organ mucosa" EXACT [OBOL:automatic] xref: FMA:18357 is_a: UBERON:0019042 ! reproductive system mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum relationship: part_of UBERON:0003984 ! uterine tube infundibulum [Term] id: UBERON:0005051 name: mediastinum testis namespace: uberon def: "The mediastinum testis is a network of fibrous connective tissue that extends from the upper to near the lower extremity of the testis, and is wider above than below. From its front and sides numerous imperfect septa (trabeculæ) are given off, which radiate toward the surface of the organ, and are attached to the tunica albuginea. They divide the interior of the organ into a number of incomplete spaces, called lobules. These are somewhat cone-shaped, being broad at their bases at the surface of the gland, and becoming narrower as they converge to the mediastinum. The mediastinum supports the rete testis and blood vessels of the testis in their passage to and from the substance of the gland[WP]." [Wikipedia:Mediastinum_testis] synonym: "body of highmore" EXACT [FMA:19812] synonym: "hilum of testicle" EXACT [] synonym: "mediastinum of testis" EXACT [FMA:19812] synonym: "testis mediastinum" EXACT [FMA:19812] xref: EMAPA:18331 xref: FMA:19812 xref: MA:0003240 xref: SCTID:362279007 xref: Wikipedia:Mediastinum_testis is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: has_part UBERON:0002384 ! connective tissue relationship: overlaps UBERON:0003728 ! mediastinum relationship: part_of UBERON:0000473 ! testis property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg" xsd:anyURI [Term] id: UBERON:0005055 name: zone of long bone namespace: uberon def: "An organ part that is part of a long bone [Automatically generated definition]." [OBOL:automatic] subset: uberon_slim synonym: "long bone zone" EXACT [] xref: FMA:24008 is_a: UBERON:0005913 ! zone of bone organ intersection_of: UBERON:0005913 ! zone of bone organ intersection_of: part_of UBERON:0002495 ! long bone relationship: part_of UBERON:0002495 ! long bone [Term] id: UBERON:0005056 name: external female genitalia namespace: uberon def: "An external genitalia that is part of a female reproductive system [Automatically generated definition]." [OBOL:automatic] comment: TODO: Relabel. Make distinct organ class. See https://github.com/obophenotype/uberon/issues/547 subset: organ_slim subset: pheno_slim synonym: "external female genital organ" EXACT [BTO:0003100] synonym: "external genitalia of female reproductive system" EXACT [OBOL:automatic] synonym: "female external genitalia" EXACT [FMA:45649] synonym: "organa genitalia feminina externa" RELATED [BTO:0003100] xref: BTO:0003100 xref: EMAPA:30984 xref: FMA:45649 xref: galen:FemaleExternalGenitalia xref: SCTID:362234008 is_a: UBERON:0003134 ! female reproductive organ is_a: UBERON:0004176 ! external genitalia intersection_of: UBERON:0004176 ! external genitalia intersection_of: part_of UBERON:0000474 ! female reproductive system disjoint_from: UBERON:0009196 ! indifferent external genitalia property_value: UBPROP:0000008 "in eutherians, this is known as the vulva in and composed of the mons pubis, the labia majora and minora, the clitoris, the vestibule of the vagina and its glands, and the opening of the urethra and of the vagina [MP:0003126]" xsd:string [Term] id: UBERON:0005057 name: immune organ namespace: uberon def: "An organ that is part of a immune system [Automatically generated definition]." [OBOL:automatic] subset: organ_slim subset: pheno_slim synonym: "immune system organ" EXACT [] is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002405 ! immune system relationship: part_of UBERON:0002405 ! immune system [Term] id: UBERON:0005058 name: hemolymphoid system gland namespace: uberon def: "A gland that is part of a hemolymphoid system [Automatically generated definition]." [OBOL:automatic] subset: organ_slim synonym: "haemolymphoid system gland" RELATED [EMAPA:18766] synonym: "hemopoietic or lymphoid gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "hemopoietic or lymphoid organ" BROAD [GO:0048534] xref: EMAPA:18766 xref: MA:0002962 is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0002193 ! hemolymphoid system relationship: part_of UBERON:0002193 ! hemolymphoid system [Term] id: UBERON:0005061 name: neural groove namespace: uberon def: "The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds." [GO:0001842, http://orcid.org/0000-0002-6601-2165, Wikipedia:Neural_groove] xref: AAO:0011071 xref: EMAPA:35594 xref: FMA:295624 xref: NCIT:C34224 xref: neuronames:1363 xref: SCTID:361463007 xref: UMLS:C0814992 {source="ncithesaurus:Neural_Groove"} xref: Wikipedia:Neural_groove xref: XAO:0000248 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0003075 ! neural plate property_value: UBPROP:0000001 "The neural groove is a shallow median groove between the neural folds of an embryo. The neural folds are two longitudinal ridges that are caused by a folding up of the ectoderm in front of the primitive streak of the developing embryo. The groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or canal, the ectodermal wall of which forms the rudiment of the nervous system. After the coalescence of the neural folds over the anterior end of the primitive streak, the blastopore no longer opens on the surface but into the closed canal of the neural tube, and thus a transitory communication, the neurenteric canal, is established between the neural tube and the primitive digestive tube. The coalescence of the neural folds occurs first in the region of the hind-brain, and from there extends forward and backward; toward the end of the third week the front opening (anterior neuropore) of the tube finally closes at the anterior end of the future brain, and forms a recess which is in contact, for a time, with the overlying ectoderm; the hinder part of the neural groove presents for a time a rhomboidal shape, and to this expanded portion the term sinus rhomboidalis has been applied. Before the neural groove is closed a ridge of ectodermal cells appears along the prominent margin of each neural fold; this is termed the neural crest or ganglion ridge, and from it the spinal and cranial nerve ganglia and the ganglia of the sympathetic nervous system are developed. By the upward growth of the mesoderm the neural tube is ultimately separated from the overlying ectoderm. The cephalic end of the neural groove exhibits several dilatations, which, when the tube is closed, assume the form of three vesicles; these constitute the three primary cerebral vesicles, and correspond respectively to the future fore-brain (prosencephalon), mid-brain (mesencephalon), and hind-brain (rhombencephalon). The walls of the vesicles are developed into the nervous tissue and neuroglia of the brain, and their cavities are modified to form its ventricles. The remainder of the tube forms the medulla spinalis or spinal cord; from its ectodermal wall the nervous and neuroglial elements of the medulla spinalis are developed while the cavity persists as the central canal[Wikipedia:Neural_groove]." xsd:string {source="Wikipedia:Neural_groove"} [Term] id: UBERON:0005062 name: neural fold namespace: uberon def: "One of the two elevated edges of the neural groove[GO,MP]." [GO:0001842, MP:0011256, Wikipedia:Neural_fold] subset: pheno_slim synonym: "medullary fold" EXACT [MP:0011256] xref: EHDAA2:0001249 xref: FMA:295618 xref: NCIT:C34223 xref: neuronames:1364 xref: SCTID:361461009 xref: UMLS:C0814993 {source="ncithesaurus:Neural_Fold"} xref: Wikipedia:Neural_fold xref: XAO:0004087 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0005157 ! epithelial fold is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0015212 ! lateral structure relationship: in_lateral_side_of UBERON:0005061 ! neural groove relationship: part_of UBERON:0005061 ! neural groove property_value: UBPROP:0000001 "In front of the primitive streak two longitudinal ridges, caused by a folding up of the ectoderm, make their appearance, one on either side of the middle line. These are named the neural folds; they commence some little distance behind the anterior end of the embryonic disk, where they are continuous with each other, and from there gradually extend backward, one on either side of the anterior end of the primitive streak. Also, after differentiation it turns into the neural tubes[Wikipedia:Neural_fold]." xsd:string {source="Wikipedia:Neural_fold"} [Term] id: UBERON:0005064 name: left ventricular trabecular myocardium namespace: uberon is_a: UBERON:0004126 ! trabecular layer of ventricle intersection_of: UBERON:0004126 ! trabecular layer of ventricle intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0003382 {source="GO"} ! cardiac muscle of left ventricle [Term] id: UBERON:0005066 name: right ventricular trabecular myocardium namespace: uberon is_a: UBERON:0004126 ! trabecular layer of ventricle intersection_of: UBERON:0004126 ! trabecular layer of ventricle intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0003381 {source="GO"} ! cardiac muscle of right ventricle [Term] id: UBERON:0005068 name: neural rod namespace: uberon def: "A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]." [GO:0014024, ZFA:0000133] subset: efo_slim synonym: "neural tube rod" RELATED [GO:0014027] xref: EFO:0003498 xref: TAO:0000133 xref: ZFA:0000133 is_a: UBERON:0016879 ! future central nervous system relationship: develops_from UBERON:0007135 ! neural keel property_value: UBPROP:0000001 "An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000133", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005075 name: forebrain-midbrain boundary namespace: uberon def: "An anatomical boundary that adjacent_to a forebrain and adjacent_to a midbrain." [OBOL:automatic] synonym: "diencephalic-mesencephalic boundary" EXACT [ZFA:0001367] synonym: "forebrain midbrain boundary" EXACT [ZFA:0001367] synonym: "forebrain-midbrain boundary region" EXACT [EMAPA:36449] xref: EMAPA:36449 xref: TAO:0001367 xref: ZFA:0001367 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: adjacent_to UBERON:0001890 ! forebrain intersection_of: adjacent_to UBERON:0001891 ! midbrain relationship: adjacent_to UBERON:0001890 ! forebrain relationship: adjacent_to UBERON:0001891 ! midbrain relationship: develops_from UBERON:0007288 {evidence="definitional"} ! presumptive forebrain midbrain boundary relationship: part_of UBERON:0000955 ! brain property_value: UBPROP:0000001 "The boundary between the diencephalon and the mesencephalon.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001367", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from forebrain midbrain boundary neural tube (TAO:0007040)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001367", ontology="TAO"} [Term] id: UBERON:0005076 name: hindbrain-spinal cord boundary namespace: uberon def: "An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord." [OBOL:automatic] synonym: "hindbrain-spinal cord boundary region" EXACT [] is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: adjacent_to UBERON:0002028 ! hindbrain intersection_of: adjacent_to UBERON:0002240 ! spinal cord relationship: adjacent_to UBERON:0002028 ! hindbrain relationship: adjacent_to UBERON:0002240 ! spinal cord relationship: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0005080 name: metanephric ureteric bud namespace: uberon def: "The portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]." [GO:0035502] is_a: UBERON:0000084 ! ureteric bud intersection_of: UBERON:0000084 ! ureteric bud intersection_of: has_potential_to_develop_into UBERON:0000081 ! metanephros relationship: has_potential_to_develop_into UBERON:0000081 ! metanephros [Term] id: UBERON:0005081 name: ureter ureteric bud namespace: uberon def: "The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]." [GO:0035503] is_a: UBERON:0000084 ! ureteric bud intersection_of: UBERON:0000084 ! ureteric bud intersection_of: has_potential_to_develop_into UBERON:0000056 ! ureter relationship: has_potential_to_develop_into UBERON:0000056 ! ureter [Term] id: UBERON:0005082 name: tube lumen namespace: uberon def: "A hole in a tube[GO]." [GO:0060609] xref: AEO:0000078 xref: EHDAA2:0004618 xref: RETIRED_EHDAA2:0003078 is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: surrounded_by UBERON:0000025 ! tube relationship: surrounded_by UBERON:0000025 ! tube [Term] id: UBERON:0005085 name: ectodermal placode namespace: uberon def: "An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO]." [GO:0060788] synonym: "epithelial placode" RELATED [AEO:0000112] xref: AEO:0000218 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0000924 ! ectoderm property_value: editor_note "consder adding placodal ectoderm as a distinct class? Also place placodal ectoderm as develops_from ectoderm; need to check taxon-appropriateness" xsd:string property_value: UBPROP:0000008 "With the exception of the adenohypophysis, homologues of the nonneurogenic placodes (e.g. placodes giving rise to the teeth, hair follicles and lens), appear to be lacking in invertebrate chordates." xsd:string property_value: UBPROP:0000012 "in GO, covers optic, otic, olfactory, mammary, hair, tooth, sebaceous - and also insect structures" xsd:string {external_ontology="GO", source="https://github.com/geneontology/go-ontology/issues/12223#issuecomment-215692347"} [Term] id: UBERON:0005087 name: tooth placode namespace: uberon def: "An tooth placode is a thickening of the ectoderm that will give rise to the tooth bud[GO]." [GO:0060790] synonym: "dental anlage" EXACT [] synonym: "dental placode" EXACT [OBOL:automatic] synonym: "dental primordium" EXACT [ZFA:0001153] synonym: "odontogenic placode" EXACT [OBOL:automatic] synonym: "tooth anlage" EXACT [MP:0000117] synonym: "tooth germ" RELATED [ZFA:0001153] synonym: "tooth primordium" EXACT [MP:0000117] xref: BTO:0001511 xref: TAO:0001153 xref: ZFA:0001153 is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0011814 {source="NCBIBook:NBK53175"} ! non-neurogenic ectodermal placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: has_potential_to_develop_into UBERON:0001091 ! calcareous tooth relationship: has_developmental_contribution_from UBERON:0004362 {notes="check for other species", source="Wikipedia:Tooth_development"} ! pharyngeal arch 1 relationship: has_potential_to_develop_into UBERON:0001091 ! calcareous tooth relationship: part_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! jaw region property_value: UBPROP:0000001 "Placode that develops into a tooth. The placode is a thickening of the pharyngeal epithelium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001153", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000015 "In mammals this may be located in the alveolar ridges, but note that some species such as zebrafish have ceratobranchial teeth. Sharks have dermal denticles that share developmental origins. Currently we don't include location information due to this diversity, but in future we may include specific subclasses and/or taxon GCIs." xsd:string [Term] id: UBERON:0005090 name: muscle structure namespace: uberon def: "Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]." [GO:0061061] synonym: "muscle" RELATED [] synonym: "muscle element" RELATED [] synonym: "musculus" EXACT [FMA:30316] xref: EMAPA:32715 xref: FMA:30316 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 ! anatomical structure relationship: has_part CL:0000187 ! muscle cell relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: IAO:0000232 "in some organisms such as drosophila, muscles can be single cells. This class groups together all discrete muscle elements, from multicellular muscle organs in vertebrates, to individual single-cell muscles in drisophila" xsd:string [Term] id: UBERON:0005092 name: right horn of sinus venosus namespace: uberon synonym: "sinus venosus right horn" EXACT [VHOG:0000489] xref: EHDAA2:0001841 xref: EHDAA:484 xref: EMAPA:16239 xref: FMA:70318 xref: VHOG:0000489 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 {source="FMA"} ! embryonic structure relationship: in_right_side_of UBERON:0002063 ! sinus venosus relationship: part_of UBERON:0002063 ! sinus venosus property_value: UBPROP:0000003 "Three major adaptations, or 'novel cardiac components', that were not present in the ancestor chordate heart tube can be distinguished in the lower vertebrate heart: the atrium, ventricle, and possibly the muscular sinus venosus.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000489", ontology="VHOG", source="DOI:10.1152/physrev.00006.2003 Moorman AFM, Christoffels VM, Cardiac Chamber Formation: Development, Genes, and Evolution. Physiological Reviews (2003", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005095 name: kidney rudiment namespace: uberon synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0007687 {source="GO"} ! kidney field property_value: editor_note "class added for consistency with GO - consider merging with kidney mesenchyme." xsd:string [Term] id: UBERON:0005103 name: mesonephric epithelium namespace: uberon def: "An epithelium that is part of a mesonephros [Automatically generated definition]." [OBOL:automatic] is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005106 name: metanephric tubule namespace: uberon def: "A metanephric tubule is an epithelial tube that is part of the metanephros[GO]." [GO:0072173] xref: VHOG:0001526 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005108 ! metanephric epithelium is_a: UBERON:0006555 ! excretory tube intersection_of: UBERON:0003914 ! epithelial tube intersection_of: part_of UBERON:0000081 ! metanephros property_value: UBPROP:0000003 "The ureteric diverticulum grows dorsally into the posterior region of the nephric ridge. Here it enlarges and stimulates the growth of metanephric tubules that come to make up the metanephric kidney. The metanephros becomes the adult kidney of amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001526", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.543", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005108 name: metanephric epithelium namespace: uberon def: "An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure[GO]." [GO:0072207] is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005109 name: metanephric smooth muscle tissue namespace: uberon def: "Any smooth muscle tissue that is part of a metanephros." [GO:0072208, https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005110 name: metanephric nephron namespace: uberon alt_id: UBERON:0005142 def: "A metanephric nephron is the functional unit of the metanephros[GO]." [GO:0072273] xref: VHOG:0000719 is_a: UBERON:0001285 ! nephron is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001285 ! nephron intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0003220 {source="Wikipedia", source="Wikipedia:Nephron"} ! metanephric mesenchyme relationship: develops_from UBERON:0010535 ! primitive metanephric nephron relationship: immediate_transformation_of UBERON:0010535 {source="Bgee:AN"} ! primitive metanephric nephron relationship: part_of UBERON:0000081 ! metanephros property_value: UBPROP:0000003 "The primitive form of the vertebrate nephron consists of a vascular filtration surface overlain with podocytes, a specialized coelomic cavity to receive the ultrafiltrate, and a tubule for modification to final urine. Although previously thought to be unique to the vertebrates, this design is now known to be widespread among invertebrates, including most of the protochordates, and especially their larvae.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000719", ontology="VHOG", source="DOI:10.1093/icb/34.4.542 Ruppert EE, Evolutionary Origin of the Vertebrate Nephron. Integrative and Comparative Biology (1994)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005113 name: metanephric cortex mesenchyme namespace: uberon xref: EHDAA2:0001140 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from UBERON:0010531 {source="EHDAA2"} ! metanephros induced blastemal cells [Term] id: UBERON:0005115 name: metanephric cortical collecting duct namespace: uberon def: "The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex[GO]." [GO:0072219] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004203 ! cortical collecting duct intersection_of: UBERON:0004203 ! cortical collecting duct intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0004737 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric collecting duct relationship: part_of UBERON:0010533 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephros cortex [Term] id: UBERON:0005134 name: metanephric nephron epithelium namespace: uberon def: "The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO]." [GO:0072243] is_a: UBERON:0004211 ! nephron epithelium is_a: UBERON:0005108 ! metanephric epithelium intersection_of: UBERON:0004211 ! nephron epithelium intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005110 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! metanephric nephron [Term] id: UBERON:0005137 name: metanephric capsule namespace: uberon alt_id: UBERON:0005112 def: "The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage[GO]." [GO:0072213] is_a: UBERON:0002015 ! kidney capsule is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002015 ! kidney capsule intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0000081 ! metanephros [Term] id: UBERON:0005146 name: metanephric nephron tubule namespace: uberon alt_id: UBERON:0005128 alt_id: UBERON:0005152 def: "A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros[GO]." [GO:0072282] is_a: UBERON:0001231 ! nephron tubule is_a: UBERON:0005106 ! metanephric tubule is_a: UBERON:0005134 ! metanephric nephron epithelium intersection_of: UBERON:0001231 ! nephron tubule intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0003220 {source="ISBN:9780878932504"} ! metanephric mesenchyme [Term] id: UBERON:0005147 name: metanephric renal vesicle namespace: uberon def: "The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0072283] synonym: "metanephric vesicle" EXACT [] xref: EHDAA2:0001245 xref: EHDAA:9346 xref: EMAPA:27678 is_a: UBERON:0004209 ! renal vesicle is_a: UBERON:0005108 ! metanephric epithelium intersection_of: UBERON:0004209 ! renal vesicle intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0005113 {source="EHDAA2"} ! metanephric cortex mesenchyme relationship: has_potential_to_develop_into UBERON:0005134 ! metanephric nephron epithelium [Term] id: UBERON:0005153 name: epithelial bud namespace: uberon def: "A bud is a protrusion that forms from an epithelial sheet by localized folding." [GO:0060572] xref: BTO:0001639 is_a: UBERON:0005157 ! epithelial fold [Term] id: UBERON:0005154 name: epithelial cord namespace: uberon def: "A cord of epithelial cells without a lumen and usually several cells thick." [AEO:0000216] xref: AEO:0000216 xref: EHDAA2:0004052 is_a: UBERON:0000486 {source="AEO"} ! multilaminar epithelium [Term] id: UBERON:0005156 name: reproductive structure namespace: uberon def: "Any anatomical structure that is part of the reproductive system." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "reproductive system element" EXACT [] synonym: "reproductive system structure" EXACT [] is_a: UBERON:0010000 ! multicellular anatomical structure intersection_of: UBERON:0010000 ! multicellular anatomical structure intersection_of: part_of UBERON:0000990 ! reproductive system relationship: part_of UBERON:0000990 ! reproductive system [Term] id: UBERON:0005157 name: epithelial fold namespace: uberon def: "An epithelial sheet bent on a linear axis." [GO:0060571] is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0005158 name: parenchyma of central nervous system namespace: uberon def: "The functional tissue of the central nervous system consisting of neurons and glial cells." [CL:tm, https://github.com/obophenotype/uberon/issues/8] synonym: "central nervous system parenchyma" EXACT [OBOL:automatic] synonym: "CNS parenchyma" EXACT [OBOL:automatic] synonym: "parenchyma of central nervous system" EXACT [] synonym: "parenchyma of CNS" EXACT [OBOL:automatic] is_a: UBERON:0000353 ! parenchyma is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0001017 ! central nervous system relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/tmeehan relationship: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0005162 name: multi cell part structure namespace: uberon def: "A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part." [CARO:0001000] subset: upper_level synonym: "cell part cluster" RELATED [FMA:83115] synonym: "multi-cell-component structure" EXACT [CARO:0001000] synonym: "multi-cell-part structure" EXACT [CARO:0001000] xref: AAO:0011000 xref: CARO:0001000 xref: FBbt:00007060 xref: FMA:83115 is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of GO:0005575 ! cellular_component property_value: UBPROP:0000012 "we go with the FMA classification rather than the CARO one. FMA def: 'Anatomical cluster which has as direct parts cell parts from two or more cells.'" xsd:string {external_ontology="CARO", external_ontology="FMA"} [Term] id: UBERON:0005169 name: interstitial tissue namespace: uberon def: "Connective tissue between the cellular elements of a structure." [http://medical-dictionary.thefreedictionary.com/tissue] subset: human_reference_atlas subset: pheno_slim synonym: "interstitium" EXACT [] xref: FMA:86301 xref: SCTID:85293002 is_a: UBERON:0003891 {source="FMA"} ! stroma property_value: editor_note "specify differentia from stroma" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "interstital" xsd:string [Term] id: UBERON:0005171 name: hepatic duct namespace: uberon def: "Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion)." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: vertebrate_core xref: EHDAA2:0000741 xref: EHDAA:3049 xref: EMAPA:16843 xref: FMA:71891 xref: galen:HepaticDuct xref: MA:0000357 xref: NCIT:C32730 xref: SCTID:245399002 xref: UMLS:C0917710 {source="ncithesaurus:Hepatic_Duct"} xref: VHOG:0000219 is_a: UBERON:0002394 ! bile duct relationship: connects UBERON:0001174 ! common bile duct relationship: connects UBERON:0002107 ! liver property_value: editor_note "TODO - MA distinguishes between bile duct, hepatic duct, common bile duct and common hepatic duct. in FMA hepatic duct and common hepatic duct are the same" xsd:string property_value: UBPROP:0000001 "A duct that carries bile from the liver to the small intestine.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001100", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The excretory duct of the liver or one of its branches in the lobes of the liver. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000219", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/hepatic+duct"} property_value: UBPROP:0000001 "The hepatic duct is the duct that leads from the liver to the bile duct[GO]." xsd:string {source="GO:0061011"} [Term] id: UBERON:0005172 name: abdomen element namespace: uberon def: "An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "abdomen organ" EXACT [MA:0000522] xref: MA:0000522 xref: SCTID:272631008 is_a: UBERON:0005173 ! abdominal segment element intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0000916 ! abdomen relationship: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0005173 name: abdominal segment element namespace: uberon def: "An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "abdominal segment organ" EXACT [MA:0000529] xref: EMAPA:37062 {source="MA:th"} xref: MA:0000529 is_a: UBERON:0005177 ! trunk region element intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0005174 name: dorsal region element namespace: uberon def: "An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "back organ" EXACT [MA:0001901] synonym: "dorsal region organ" EXACT [] xref: EMAPA:37274 {source="MA:th"} xref: MA:0001901 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0005176 name: tooth enamel organ namespace: uberon def: "A circumscribed mass of ectodermal cells which bud off from the dental lamina; it becomes cup-shaped and develops on its internal face the ameloblast layer of cells that produces the enamel cap of a developing tooth." [https://github.com/cerivs/zebrafish-anatomical-ontology/issues/107, https://github.com/obophenotype/uberon/issues/1313, ISBN:0-683-40008-8, MP:0010747, Wikipedia:Enamel_organ] comment: . Alternate definition: A cellular aggregation seen in histologic sections of a developing tooth. It lies above a condensation of ectomesenchymal cells called the odontogenic papilla. subset: pheno_slim subset: vertebrate_core synonym: "dental organ" EXACT [ZFA:0005138] synonym: "enamel organ" EXACT [MP:0010747] synonym: "odontogenic organ" RELATED [] synonym: "organum enameleum" RELATED LATIN [Wikipedia:Enamel_organ] xref: BTO:0001722 xref: CALOHA:TS-0271 xref: EMAPA:32888 xref: FMA:312389 xref: MA:0001604 xref: MESH:D004658 xref: SCTID:362863002 xref: TAO:0005138 xref: Wikipedia:Enamel_organ xref: ZFA:0005138 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034922 ! cell cluster relationship: part_of UBERON:0008281 ! tooth bud property_value: RO:0002161 NCBITaxon:8782 property_value: UBPROP:0000001 "A structure that is involved in tooth formation. A bell shape two layer epithelial structure that descends toward the ceratobranchial 5 bone, enclosing the dental mesenchyme. At later times in tooth development the cells at the apex of the bell may be involved in enameloid formation. This structure remains at the base of the erupted tooth and is the source of replacement teeth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005138", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000011 "NOT develops_from NC[https://github.com/obophenotype/uberon/wiki/The-neural-crest]" xsd:string property_value: UBPROP:0000013 "Historically, enamel organ has been the term to describe this structure, but it was attempted unsuccessfully in recent years to change the name to dental organ in order to better represent its multiple functions apart from enamel formation" xsd:string [Term] id: UBERON:0005177 name: trunk region element namespace: uberon def: "An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions." [http://orcid.org/0000-0002-6601-2165] subset: non_informative subset: organ_slim synonym: "trunk organ" EXACT [MA:0000516] xref: EMAPA:37270 {source="MA:th"} xref: MA:0000516 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0005178 name: thoracic cavity element namespace: uberon def: "An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli." [http://orcid.org/0000-0002-6601-2165] subset: non_informative subset: pheno_slim synonym: "thoracic cavity organ" EXACT [MA:0000557] xref: EMAPA:37273 {source="MA:th"} xref: MA:0000557 is_a: UBERON:0002075 ! viscus is_a: UBERON:0005181 ! thoracic segment organ intersection_of: UBERON:0000062 ! organ intersection_of: located_in UBERON:0002224 ! thoracic cavity relationship: located_in UBERON:0002224 ! thoracic cavity [Term] id: UBERON:0005179 name: pelvic region element namespace: uberon def: "An organ or element that is part of the pelvic region. Examples: reproductive organs (in some organisms), urinary bladder, bones of the pelvis." [http://orcid.org/0000-0002-6601-2165] subset: non_informative subset: organ_slim subset: pheno_slim synonym: "pelvic element" EXACT [] synonym: "pelvis organ" EXACT [MA:0000543] synonym: "pelvis region organ" EXACT [] xref: EMAPA:37275 {source="MA:th"} xref: MA:0000543 is_a: UBERON:0005173 ! abdominal segment element intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002355 ! pelvic region of trunk [Term] id: UBERON:0005181 name: thoracic segment organ namespace: uberon def: "An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "upper body organ" RELATED [MA:0000563] xref: EMAPA:37271 {source="MA:th"} xref: MA:0000563 is_a: UBERON:0005177 ! trunk region element intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0005192 name: deferent duct artery namespace: uberon def: "An artery in males that provides blood to the vas deferens. The artery usually arises from the anterior trunk of the superior vesical artery. It accompanies the vas deferens into the testis, where it anastomoses with the testicular artery. In this way it also supplies blood to the testis and epididymis. A small branch supplies the ureter[WP]." [Wikipedia:Artery_to_the_ductus_deferens] subset: human_reference_atlas synonym: "arteria ductus deferentis" EXACT LATIN [Wikipedia:Artery_to_the_ductus_deferens] synonym: "artery of ductus deferens" EXACT [FMA:18930] synonym: "ductus deferens artery" EXACT [FMA:18930] synonym: "vas deferens artery" EXACT [] xref: EMAPA:37513 {source="MA:th"} xref: FMA:18930 xref: MA:0001940 xref: SCTID:279659005 xref: Wikipedia:Artery_to_the_ductus_deferens is_a: UBERON:0004573 ! systemic artery is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001000 ! vas deferens relationship: branching_part_of UBERON:0001310 {source="FMA"} ! umbilical artery relationship: branching_part_of UBERON:0001312 {source="Wikipedia"} ! superior vesical artery relationship: part_of UBERON:0001310 ! umbilical artery relationship: part_of UBERON:0001312 ! superior vesical artery relationship: part_of UBERON:0005352 ! spermatic cord relationship: supplies UBERON:0001000 ! vas deferens property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0005194 name: thoracic vein namespace: uberon def: "A vein that is part of a thorax [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37197 {source="MA:th"} xref: MA:0002235 xref: NCIT:C53142 xref: SCTID:281472008 xref: UMLS:C0226629 {source="ncithesaurus:Thoracic_Vein"} is_a: UBERON:0001638 ! vein is_a: UBERON:0003834 ! thoracic segment blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0000915 ! thoracic segment of trunk [Term] id: UBERON:0005195 name: deferent duct vein namespace: uberon def: "A vein that is part of a vas deferens [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:37514 {source="MA:th"} xref: MA:0002100 is_a: UBERON:0001638 ! vein is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001000 ! vas deferens relationship: part_of UBERON:0001000 ! vas deferens [Term] id: UBERON:0005203 name: trachea gland namespace: uberon def: "A tubuloacinar seromucous gland that is located principally in the submucosa of the trachea. Excretory ducts from this gland pass through the lamina propria to the tracheal lumen." [http://medical-dictionary.thefreedictionary.com/tracheal+glands, https://github.com/obophenotype/uberon/issues/1197, ISBN:1451113412, MGI:Anna, PMID:15973734] subset: human_reference_atlas subset: organ_slim subset: pheno_slim synonym: "glandula trachealis" EXACT [FMA:7473] synonym: "tracheal gland" EXACT [FMA:7473] synonym: "tubular seromucous gland of trachea" RELATED [FMA:7473] xref: EMAPA:36574 xref: FMA:7473 xref: MA:0002937 xref: SCTID:197423006 is_a: UBERON:8410077 ! airway submucosal gland intersection_of: UBERON:0011148 ! submucosal gland intersection_of: has_part CL:0000159 ! seromucus secreting cell intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0003126 ! trachea property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000009 "These glands secrete mucus, lysozyme, defensins, and other agents that help protect the lungs from particles and infectious agents." xsd:string [Term] id: UBERON:0005204 name: larynx submucosa gland namespace: uberon def: "A gland that is part of a larynx submucosa [Automatically generated definition]." [OBOL:automatic] subset: organ_slim synonym: "laryngeal submucosa gland" RELATED [EMAPA:35475] xref: EMAPA:35475 xref: MA:0002729 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0004778 ! larynx submucosa relationship: part_of UBERON:0004778 ! larynx submucosa [Term] id: UBERON:0005208 name: right atrium valve namespace: uberon def: "A valve that is part of a right atrium [Automatically generated definition]." [OBOL:automatic] synonym: "right atrium valves" RELATED PLURAL [EHDAA2:0000302] synonym: "superior vena cava valve" RELATED [EMAPA:17327] synonym: "valve of right atrium" EXACT [EMAPA:17327] xref: EHDAA2:0000302 xref: EMAPA:17327 xref: MA:0001871 is_a: UBERON:0003978 ! valve is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003978 ! valve intersection_of: part_of UBERON:0002078 ! right cardiac atrium relationship: part_of UBERON:0002078 ! right cardiac atrium [Term] id: UBERON:0005215 name: kidney interstitium namespace: uberon def: "The interstitial compartment of the kidney, comprising the extravascular intertubular spaces of the renal parenchyma, with their attendant cellular elements and extracellular substances, bounded on all sides by epithelial and vascular basement membranes." [DOI:10.1038/ki.1991.49, http://orcid.org/0000-0002-6601-2165, PMID:18575881] subset: human_reference_atlas subset: pheno_slim synonym: "interstitial tissue of kidney" EXACT [] synonym: "kidney interstitium group" RELATED [EMAPA:28518] synonym: "renal interstitial tissue" EXACT [] synonym: "renal interstitium" EXACT [FMA:70983] synonym: "renal stroma" EXACT [FMA:70983] synonym: "stroma of kidney" EXACT [FMA:70983] xref: EMAPA:28518 xref: FMA:70983 xref: MA:0002616 xref: NCIT:C33459 xref: SCTID:362210003 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005169 ! interstitial tissue intersection_of: UBERON:0005169 ! interstitial tissue intersection_of: part_of UBERON:0002113 ! kidney relationship: composed_primarily_of CL:1000692 ! kidney interstitial fibroblast relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney property_value: editor_note "See https://sourceforge.net/p/geneontology/ontology-requests/10941/" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000009 "The interstitium is necessarily involved in all intrarenal exchange processes since the reabsorption and secretion of fluid and solutes implicates a transit across the interstitial compartment." xsd:string property_value: UBPROP:0000010 "The fibroblasts in the interstitium provide the 'skeleton' of the tissue and maintain the three-dimensional architecture of the tissue." xsd:string [Term] id: UBERON:0005216 name: optic eminence surface ectoderm namespace: uberon def: "An external ectoderm that is part of a optic eminence [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:16539 xref: RETIRED_EHDAA2:0001311 xref: VHOG:0000520 is_a: UBERON:0000076 ! external ectoderm intersection_of: UBERON:0000076 ! external ectoderm intersection_of: part_of UBERON:0004348 ! optic eminence relationship: part_of UBERON:0005234 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! optic eminence ectoderm [Term] id: UBERON:0005221 name: liver right lobe parenchyma namespace: uberon def: "A parenchyma that is part of a right lobe of liver [Automatically generated definition]." [OBOL:automatic] synonym: "parenchyma of right lobe of liver" EXACT [FMA:71657] xref: EHDAA2:0001010 xref: EMAPA:18317 xref: FMA:71657 xref: VHOG:0000840 is_a: UBERON:0001280 ! liver parenchyma intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0001114 ! right lobe of liver relationship: part_of UBERON:0001114 ! right lobe of liver [Term] id: UBERON:0005222 name: liver left lobe parenchyma namespace: uberon def: "A parenchyma that is part of a left lobe of liver [Automatically generated definition]." [OBOL:automatic] synonym: "parenchyma of left lobe of liver" EXACT [FMA:71658] xref: EHDAA2:0001002 xref: EMAPA:18310 xref: FMA:71658 xref: VHOG:0000839 is_a: UBERON:0001280 ! liver parenchyma intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0001115 ! left lobe of liver relationship: part_of UBERON:0001115 ! left lobe of liver [Term] id: UBERON:0005225 name: upper leg epithelium namespace: uberon def: "An epithelium that is part of a hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0002131 xref: EMAPA:17500 xref: VHOG:0001041 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0005226 name: pedal digit epithelium namespace: uberon def: "An epithelium that is part of a toe [Automatically generated definition]." [OBOL:automatic] synonym: "foot digit epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit epithelium" EXACT [OBOL:accepted] synonym: "toe epithelium" EXACT [] xref: EMAPA:32946 xref: VHOG:0001031 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001466 ! pedal digit relationship: develops_from UBERON:0003248 {source="EHDAA2"} ! epithelium of footplate relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0005227 name: manual digit epithelium namespace: uberon def: "An epithelium that is part of a finger [Automatically generated definition]." [OBOL:automatic] synonym: "finger epithelium" EXACT [] synonym: "fore limb digit epithelium" EXACT [OBOL:accepted] synonym: "hand digit epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] xref: EHDAA2:0000406 xref: EMAPA:32647 xref: VHOG:0001032 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002389 ! manual digit relationship: develops_from UBERON:0010332 {source="EHDAA2"} ! epithelium of handplate relationship: part_of UBERON:0002389 ! manual digit [Term] id: UBERON:0005228 name: upper arm epithelium namespace: uberon def: "An epithelium that is part of a forelimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0002113 xref: EMAPA:17425 xref: VHOG:0000990 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0003822 ! forelimb stylopod [Term] id: UBERON:0005229 name: lower leg epithelium namespace: uberon def: "An epithelium that is part of a lower leg [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0001031 xref: EMAPA:17497 xref: VHOG:0001050 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm relationship: part_of UBERON:0003823 ! hindlimb zeugopod [Term] id: UBERON:0005233 name: medial-nasal process ectoderm namespace: uberon def: "An ectoderm that is part of a medial nasal prominence [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0001078 xref: EMAPA:16809 xref: FMA:312675 xref: VHOG:0000803 is_a: UBERON:0000924 ! ectoderm is_a: UBERON:0014702 ! frontonasal process epithelium intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0004068 ! medial nasal prominence relationship: part_of UBERON:0004068 ! medial nasal prominence [Term] id: UBERON:0005234 name: optic eminence ectoderm namespace: uberon def: "An ectoderm that is part of a optic eminence [Automatically generated definition]." [OBOL:automatic] xref: EHDAA:940 xref: EMAPA:16539 xref: RETIRED_EHDAA2:0001309 xref: VHOG:0001105 is_a: UBERON:0000924 ! ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0004348 ! optic eminence relationship: part_of UBERON:0004348 ! optic eminence [Term] id: UBERON:0005239 name: basal plate metencephalon namespace: uberon synonym: "metencephalon basal plate" EXACT [EHDAA2:0001154] xref: EHDAA2:0001154 xref: EMAPA:17078 xref: VHOG:0000320 is_a: UBERON:0004064 ! neural tube basal plate property_value: UBPROP:0000001 "The ventral half of the developing neural tube that is the metencephalon. [Chordate_evolution_and_the_origin_of_craniates:_An_old_brain_in_a_new_head._AnaT_Rec_(New_Anat)_(2000)_261(3):_111-125, See_Butler_AB][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000320", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005243 name: interventricular septum endocardium namespace: uberon def: "An endocardium that is part of a interventricular septum [Automatically generated definition]." [OBOL:automatic] synonym: "endocardium of interventricular septum" EXACT [FMA:83584] synonym: "interventricular septum endocardial tissue" RELATED [VHOG:0000615] xref: EHDAA2:0000886 xref: EHDAA2:0000887 xref: FMA:83584 xref: VHOG:0000615 is_a: UBERON:0002165 ! endocardium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002094 ! interventricular septum relationship: part_of UBERON:0002094 ! interventricular septum property_value: editor_note "TODO - split?" xsd:string [Term] id: UBERON:0005248 name: bulbus cordis myocardium namespace: uberon def: "A myocardium that is part of a bulbus cordis [Automatically generated definition]." [OBOL:automatic] synonym: "bulbus cordis cardiac muscle" RELATED [VHOG:0000609] xref: EMAPA:36488 xref: VHOG:0000609 is_a: UBERON:0002349 ! myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0004706 ! bulbus cordis relationship: part_of UBERON:0004706 ! bulbus cordis [Term] id: UBERON:0005249 name: metanephric renal pelvis namespace: uberon def: "A renal pelvis that is part of a metanephros." [OBOL:automatic] synonym: "metanephros pelvis" EXACT [VHOG:0000945] xref: VHOG:0000945 is_a: UBERON:0001224 ! renal pelvis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001224 ! renal pelvis intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0000081 ! metanephros property_value: UBPROP:0000003 "The ureteric bud itself forms the collecting tubules and the ureter that drain the adult kidney. This type of kidney, called the metanephros, occurs in all adult amniotes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000945", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.639", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005250 name: stomatodeum gland namespace: uberon def: "A gland that is part of a stomodeum." [OBOL:automatic] subset: organ_slim synonym: "stomatodaeum gland" EXACT [VHOG:0000658] xref: VHOG:0000658 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000930 ! stomodeum relationship: part_of UBERON:0000930 ! stomodeum property_value: editor_note "check this" xsd:string [Term] id: UBERON:0005251 name: yolk sac cavity namespace: uberon def: "An anatomical cavity that is part of a yolk sac [Automatically generated definition]." [OBOL:automatic] synonym: "cavity of yolk sac" EXACT [FMA:63942] synonym: "yolk sac lumen" EXACT [] synonym: "yolk sac space" RELATED [FMA:63942] xref: EMAPA:16055 xref: FMA:63942 xref: VHOG:0000843 is_a: UBERON:0002553 ! anatomical cavity is_a: UBERON:0007473 ! lumen of epithelial sac is_a: UBERON:0012466 ! extraembryonic cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0001040 ! yolk sac relationship: luminal_space_of UBERON:0001040 ! yolk sac relationship: part_of UBERON:0001040 ! yolk sac property_value: UBPROP:0000008 "In mammals, the yolk sac cavity contains fluid rather than platelets" xsd:string {source="ISBN:0073040584"} property_value: UBPROP:0000012 "in EHDAA2, there are separate primary and secondary yolk sac cavities" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0005253 name: head mesenchyme namespace: uberon def: "Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells." [ISBN:0683400088, MP:0011260] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "cephalic mesenchyme" EXACT [MP:0011260] synonym: "cranial mesenchyme" RELATED [MGI:anna] synonym: "desmocranium" RELATED PENDING_REVIEW [FMA:76622] xref: EFO:0003492 xref: EHDAA2:0000732 xref: EHDAA:179 xref: EMAPA:16098 xref: EMAPA_RETIRED:16269 xref: FMA:76622 xref: TAO:0000113 xref: VHOG:0000332 xref: ZFA:0000113 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme property_value: UBPROP:0000001 "Mesoderm that will give rise, along with cranial neural crest cells, to connective tissue, bone and musculature in the head. (Source: BioGlossary, www.Biology-Text.com)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000113", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005254 name: upper leg mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing hindlimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0002132 xref: EMAPA:17501 xref: VHOG:0000506 is_a: UBERON:0003860 ! hindlimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0005255 name: pedal digit mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing toe [Automatically generated definition]." [OBOL:automatic] synonym: "finger ray mesenchyme" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "foot digit mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit mesenchyme" EXACT [OBOL:accepted] synonym: "pedal digital ray mesenchyme" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "toe mesenchyme" EXACT [] xref: EMAPA:32947 xref: VHOG:0000463 is_a: UBERON:0003860 ! hindlimb mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010702 ! digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001466 ! pedal digit relationship: develops_from UBERON:0003328 {source="EHDAA2"} ! mesenchyme of footplate relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0005256 name: trunk mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing trunk." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "trunk and cervical mesenchyme" RELATED [EHDAA2:0002092] xref: EFO:0003485 xref: EHDAA2:0002092 xref: EHDAA:377 xref: EMAPA:16177 xref: TAO:0000081 xref: VHOG:0000281 xref: ZFA:0000081 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000922 ! embryo intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme [Term] id: UBERON:0005257 name: manual digit mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing finger [Automatically generated definition]." [OBOL:automatic] synonym: "anterior limb digital ray mesenchyme" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "finger mesenchyme" EXACT [] synonym: "finger ray mesenchyme" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "fore limb digit mesenchyme" EXACT [OBOL:accepted] synonym: "hand digit mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digital ray mesenchyme" RELATED [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0000407 xref: EMAPA:32645 xref: VHOG:0001416 is_a: UBERON:0003859 ! forelimb mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010702 ! digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002389 ! manual digit relationship: develops_from UBERON:0009523 ! mesenchyme of handplate relationship: part_of UBERON:0002389 ! manual digit property_value: editor_note "In EHDAA2, the metacarpal cartilage condensation is considered part of the digits - it might be better to call the whole structure digital ray mesenchyme/condensation" xsd:string [Term] id: UBERON:0005258 name: upper arm mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing forelimb stylopod [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0002114 xref: EMAPA:17426 xref: VHOG:0000505 is_a: UBERON:0003859 ! forelimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: part_of UBERON:0003822 ! forelimb stylopod [Term] id: UBERON:0005259 name: lower leg mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing lower leg [Automatically generated definition]." [OBOL:automatic] xref: EHDAA2:0001032 xref: EMAPA:17498 xref: VHOG:0000752 is_a: UBERON:0003860 ! hindlimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0003823 ! hindlimb zeugopod [Term] id: UBERON:0005268 name: renal cortex artery namespace: uberon def: "An artery that supplies the renal cortex." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "kidney cortex artery" EXACT [MP:0011314] synonym: "renal cortex arterial system" RELATED [MA:0002582] synonym: "renal cortex artery" EXACT [MA:0002582] xref: EMAPA:28147 xref: MA:0002582 is_a: UBERON:0001637 ! artery is_a: UBERON:0003644 ! kidney arterial blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001225 ! cortex of kidney relationship: contributes_to_morphology_of UBERON:0001225 ! cortex of kidney relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney relationship: supplies UBERON:0001225 ! cortex of kidney [Term] id: UBERON:0005269 name: renal cortex vein namespace: uberon def: "Artery that receives blood from the renal cortex[MP, modified]." [MGI:csmith] subset: pheno_slim synonym: "kidney cortex vein" RELATED [MP:0011322] synonym: "renal cortex venous system" RELATED [MA:0002592] xref: EMAPA:28152 xref: MA:0002592 is_a: UBERON:0013126 ! vein of abdomen is_a: UBERON:0014401 ! renal venous blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001225 ! cortex of kidney relationship: contributes_to_morphology_of UBERON:0001225 ! cortex of kidney relationship: drains UBERON:0001225 ! cortex of kidney relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney [Term] id: UBERON:0005270 name: renal cortex interstitium namespace: uberon def: "A compartment of the renal cortex situated between basement membranes of epithelia and vessels that contains two contiguous cellular networks in mutual contact, one formed by interstitial fibroblasts, the other by dendritic cells." [PMID:18575881] synonym: "cortical stroma" RELATED [EMAPA:28136] synonym: "kidney cortex interstitium" EXACT [MA:0002608] synonym: "renal cortical interstitial tissue" EXACT [] xref: EMAPA:28136 xref: MA:0002608 xref: SCTID:243707006 xref: Wikipedia:Medullary_interstitium is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0005215 ! kidney interstitium intersection_of: UBERON:0005169 ! interstitial tissue intersection_of: part_of UBERON:0001225 ! cortex of kidney relationship: has_part CL:0000057 ! fibroblast relationship: has_part CL:0000451 ! dendritic cell relationship: part_of UBERON:0001225 {source="MA"} ! cortex of kidney relationship: part_of UBERON:0005215 {source="MA"} ! kidney interstitium property_value: UBPROP:0000010 "In the renal cortex, interstitial fibroblasts produce erythropoietin and are distinguished from other interstitial cells by their prominent F-actin cytoskeleton, abundance of rough endoplasmic reticulum, and by ecto-5'-nucleotidase expression in their plasma membrane. The resident dendritic cells belong to the mononuclear phagocyte system and fulfil a sentinel function. They are characterized by their expression of MHC class II and CD11c." xsd:string {source="PMID:18575881"} [Term] id: UBERON:0005275 name: dorsal skin of digit namespace: uberon synonym: "dorsal digit skin" EXACT [] synonym: "skin of dorsal part of digit" EXACT [] is_a: UBERON:0015249 ! digit skin [Term] id: UBERON:0005276 name: dorsal skin of finger namespace: uberon def: "A dorsal skin of digit that is part of a manual digit." [OBOL:automatic] synonym: "dorsal finger skin" EXACT [] synonym: "skin of dorsal part of finger" EXACT [FMA:38320] synonym: "subdivision of skin of dorsal part of finger" EXACT [FMA:60346] xref: FMA:38320 xref: FMA:60346 is_a: UBERON:0003533 ! manual digit skin is_a: UBERON:0005275 ! dorsal skin of digit intersection_of: UBERON:0005275 ! dorsal skin of digit intersection_of: part_of UBERON:0002389 ! manual digit property_value: UBPROP:0000012 "this class is explicitly the union of the two FMA classes" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0005277 name: dorsal skin of toe namespace: uberon def: "A dorsal skin of digit that is part of a pedal digit." [OBOL:automatic] synonym: "dorsal toe skin" EXACT [] synonym: "skin of dorsal part of toe" EXACT [FMA:37868] synonym: "subdivision of skin of dorsal part of toe" EXACT [FMA:60523] xref: FMA:37868 xref: FMA:60523 is_a: UBERON:0003530 ! pedal digit skin is_a: UBERON:0005275 ! dorsal skin of digit intersection_of: UBERON:0005275 ! dorsal skin of digit intersection_of: part_of UBERON:0001466 ! pedal digit property_value: UBPROP:0000012 "this class is explicitly the union of the two FMA classes" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0005290 name: myelencephalon namespace: uberon def: "The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]." [BTO:0000758, Wikipedia:Myelencephalon] subset: uberon_slim synonym: "myelencephalon (medulla oblongata)" RELATED [DHBA:10662] xref: BTO:0000758 xref: CALOHA:TS-0607 xref: CALOHA:TS-2365 xref: DHBA:10662 xref: EHDAA2:0001207 xref: EHDAA:5526 xref: EMAPA:17082 xref: HBA:9512 xref: MA:0000205 xref: MESH:D054024 xref: VHOG:0000456 xref: Wikipedia:Myelencephalon is_a: UBERON:0004733 ! segmental subdivision of hindbrain relationship: develops_from UBERON:0010096 ! future myelencephalon relationship: immediate_transformation_of UBERON:0010096 {evidence="definitional"} ! future myelencephalon property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/54/EmbryonicBrain.svg" xsd:anyURI property_value: RO:0002174 NCBITaxon:7955 property_value: UBPROP:0000001 "The posterior of the two brain vesicles formed by specialization of the rhombencephalon in the developing embryo, it comprises the medulla oblongata. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000456", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/myelencephalon"} property_value: UBPROP:0000003 "The early development of most vertebrate brains is similar (...). The zebrafish neural tube follows the same basic differentiation pattern as the mammalian neural tube (reference 1); The brain develops from three embryonic enlargements of the neural tube, which later differentiate into five regions. A forebrain differentiates into telencephalon and diencephalon. The midbrain, or mesencephalon, remains undivided. The hindbrain divides into the metencephalon and myelencephalon. Cavities within the brain enlarge to form a series of interconnected ventricles (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000456", ontology="VHOG", source="ISBN:978-0878932504 Gilbert SF, Developmental Biology (2006) p.381-382, ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.500", source="http://bgee.unil.ch/"} property_value: UBPROP:0000013 "the terms metencephalon and myelencephalon are only meaningful in mammals and birds - Neuroanatomy of the Zebrafish Brain. Note that its not clear if this refers to the developing medulla oblongata - MA (adult) has two distinct classes" xsd:string [Term] id: UBERON:0005291 name: embryonic tissue namespace: uberon def: "A portion of tissue that is part of an embryo." [OBOL:automatic] subset: pheno_slim subset: upper_level synonym: "developing tissue" RELATED [] synonym: "portion of embryonic tissue" EXACT [OBOL:automatic] xref: CALOHA:TS-2100 is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0002050 ! embryonic structure [Term] id: UBERON:0005292 name: extraembryonic tissue namespace: uberon def: "Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "extra-embryonic tissue" EXACT [] xref: BTO:0003360 xref: CALOHA:TS-2119 xref: EFO:0001406 xref: MAT:0000061 xref: MIAA:0000061 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: part_of UBERON:0016887 ! entire extraembryonic component relationship: part_of UBERON:0016887 ! entire extraembryonic component [Term] id: UBERON:0005294 name: gonadal ridge namespace: uberon def: "The elevation of thickened mesothelium and underlying mesenchyme found on the ventromedial border of the embryonic mesonephros in which the primordial germ cells become embedded, establishing it as the primordium of the testis or ovary." [MGI:anna, MP:0011411] subset: efo_slim subset: pheno_slim synonym: "crista gonadalis" RELATED LATIN [Wikipedia:Gonadal_ridge] synonym: "genital cord" RELATED [MP:0011411] synonym: "genital ridge" EXACT [MP:0011411, Wikipedia:Gonadal_ridge] synonym: "gonadal ridge" EXACT [Wikipedia:Gonadal_ridge] synonym: "indifferent gonadal ridge" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0011047 xref: BTO:0001402 xref: EFO:0001414 xref: EHDAA2:0004044 xref: EMAPA:35899 xref: FMA:321917 xref: NCIT:C34184 xref: NCIT:C34321 xref: SCTID:308801004 xref: SCTID:361399001 xref: UMLS:C0231047 {source="ncithesaurus:Urogenital_Ridge"} xref: UMLS:C1512243 {source="ncithesaurus:Gonadal_Ridge"} xref: Wikipedia:Gonadal_ridge xref: XAO:0000018 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0004876 ! urogenital fold relationship: part_of UBERON:0004122 ! genitourinary system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray1106.png" xsd:anyURI property_value: editor_note "TODO - check developmental relationships. merge with urogenital ridge?" xsd:string property_value: UBPROP:0000011 "in eutherians, SRY transforms the indifferent gonad into testes" xsd:string [Term] id: UBERON:0005295 name: sex cord namespace: uberon def: "Cordlike masses of epithelial tissue that invaginate from germinal epithelium of the gonad and give rise to seminiferous tubules and rete testes in the male, and primary ovarian follicles and rete ovarii in the female." [http://www.answers.com/topic/sex-cord, Wikipedia:Sex_cords] synonym: "genital cord" RELATED [] synonym: "gonad cord" RELATED [] synonym: "gonadal cord" RELATED [] synonym: "primitive sex cord" RELATED [] xref: EHDAA2:0004051 xref: NCIT:C34183 xref: RETIRED_EHDAA2:0001523 xref: SCTID:343823004 xref: UMLS:C1512242 {source="ncithesaurus:Gonadal_Cord"} xref: Wikipedia:Sex_cords is_a: UBERON:0005154 {source="EHDAA2"} ! epithelial cord is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0012275 ! meso-epithelium relationship: develops_from UBERON:0005294 ! gonadal ridge [Term] id: UBERON:0005296 name: ovary sex cord namespace: uberon def: "Structures that develop from sex cords in the female. After further development they become the ovarian follicles." [Wikipedia:Cortical_cords] synonym: "cortical cord" RELATED [] synonym: "cortical sex cord" RELATED [] synonym: "ovary primitive sex cord" RELATED [] synonym: "ovigerous cord" EXACT [] synonym: "ovigerous cords" EXACT PLURAL [VHOG:0001339] synonym: "secondary cord" RELATED [] xref: EHDAA2:0001363 xref: EHDAA:8130 xref: EMAPA:31058 xref: NCIT:C34134 xref: UMLS:C1511527 {source="ncithesaurus:Cortical_Cord"} xref: VHOG:0001339 xref: Wikipedia:Cortical_cords is_a: UBERON:0004911 ! epithelium of female gonad is_a: UBERON:0005295 ! sex cord intersection_of: UBERON:0005295 ! sex cord intersection_of: part_of UBERON:0000992 ! ovary relationship: develops_from UBERON:0010141 ! primitive sex cord of indifferent gonad property_value: editor_note "TODO check secondary vs cortical vs ovary" xsd:string [Term] id: UBERON:0005297 name: testis sex cord namespace: uberon def: "The testis cords are precursors to the rete testis. They play several different roles in the development of the male genitals[WP]." [Wikipedia:Testis_cords] subset: pheno_slim synonym: "primary sex cord" RELATED [] synonym: "testis cord" EXACT [MP:0006424] synonym: "testis primary sex cords" EXACT [EHDAA2:0002011] synonym: "testis primitive sex cord" RELATED [] xref: EHDAA2:0002011 xref: EHDAA:8152 xref: EMAPA:29098 xref: VHOG:0001321 xref: Wikipedia:Testis_cords is_a: UBERON:0004910 ! epithelium of male gonad is_a: UBERON:0005295 ! sex cord intersection_of: UBERON:0005295 ! sex cord intersection_of: part_of UBERON:0000473 ! testis relationship: develops_from UBERON:0010141 ! primitive sex cord of indifferent gonad relationship: immediate_transformation_of UBERON:0010141 {source="Bgee:AN"} ! primitive sex cord of indifferent gonad property_value: editor_note "TODO - check primary vs testis" xsd:string [Term] id: UBERON:0005298 name: skin of clitoris namespace: uberon def: "A zone of skin that is part of a clitoris [Automatically generated definition]." [OBOL:automatic] synonym: "clitoris skin" EXACT [] xref: FMA:20168 xref: SCTID:361374002 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:8480029 ! skin of external genitalia intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002411 ! clitoris relationship: part_of UBERON:0002411 ! clitoris [Term] id: UBERON:0005309 name: pronephric nephron namespace: uberon def: "A pronephric nephron is the functional unit of the pronephros[GO]." [GO:0039019] xref: AAO:0011091 xref: XAO:0000285 is_a: UBERON:0001285 ! nephron is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001285 ! nephron intersection_of: part_of UBERON:0002120 ! pronephros relationship: part_of UBERON:0002120 ! pronephros property_value: UBPROP:0000001 "The structure that is the basic functional unit of the pronephros.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011091", ontology="AAO", source="UBERON:0005309"} [Term] id: UBERON:0005310 name: pronephric nephron tubule namespace: uberon def: "The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct[GO]." [GO:0039020] synonym: "ciliated neck segment" RELATED [ZFA:0001558] synonym: "pronephric tubule" EXACT [ZFA:0001558] xref: TAO:0001558 xref: XAO:0004105 xref: ZFA:0001558 is_a: UBERON:0001231 ! nephron tubule is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0001231 ! nephron tubule intersection_of: part_of UBERON:0005309 ! pronephric nephron relationship: part_of UBERON:0005309 {source="GO"} ! pronephric nephron property_value: RO:0002174 NCBITaxon:32524 {source="ISBN:0073040584"} property_value: UBPROP:0000001 "Bilaterally paired tubes connecting the pronephric glomeruli to the pronephric ducts. In zebrafish and other teleosts, the pronephric nephron and tubules form after the pronephric duct, connecting to the anterior-most tip of the pronephric ducts. Drummond, 2000.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001558", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005316 name: endocardial endothelium namespace: uberon def: "The endothelial lining of the endocardium." [UBERON:cjm] synonym: "endocardium endothelium" EXACT [FMA:83596] synonym: "endothelium of endocardium" EXACT [FMA:83596] xref: FMA:83596 is_a: UBERON:0008307 ! heart endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002165 ! endocardium relationship: part_of UBERON:0002165 ! endocardium [Term] id: UBERON:0005317 name: pulmonary artery endothelium namespace: uberon def: "An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]." [GO:0061155] synonym: "pulmonary artery endothelial tube" EXACT [GO:0061155] xref: BTO:0000137 is_a: UBERON:0001917 ! endothelium of artery intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: part_of UBERON:0002012 ! pulmonary artery [Term] id: UBERON:0005319 name: mesonephric collecting duct namespace: uberon def: "The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder[GO]." [GO:0061211] xref: AAO:0010390 xref: XAO:0000151 is_a: UBERON:0001232 ! collecting duct of renal tubule is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001232 ! collecting duct of renal tubule intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005322 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric nephron [Term] id: UBERON:0005321 name: mesonephric smooth muscle tissue namespace: uberon is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005322 name: mesonephric nephron namespace: uberon def: "A nephron that is part of a mesonephros." [http://orcid.org/0000-0002-6601-2165] synonym: "nephron of mesonephros" EXACT [] synonym: "stage IV nephron" RELATED [ZFA:0005592] xref: AAO:0010387 xref: XAO:0000292 xref: ZFA:0005592 is_a: UBERON:0001285 ! nephron is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001285 ! nephron intersection_of: part_of UBERON:0000080 ! mesonephros relationship: develops_from UBERON:0005323 {source="XAO"} ! mesonephric mesenchyme relationship: part_of UBERON:0000080 ! mesonephros property_value: UBPROP:0000001 "The structure that is the basic functional unit of the kidney.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010387", ontology="AAO", source="PMID:9268568"} [Term] id: UBERON:0005323 name: mesonephric mesenchyme namespace: uberon def: "Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros[GO]." [GO:0061219] subset: pheno_slim xref: AAO:0011062 xref: EHDAA2:0001132 xref: EMAPA:16745 xref: XAO:0000291 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0005330 name: mesonephric nephron epithelium namespace: uberon def: "The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO]." [GO:0061241] is_a: UBERON:0004211 ! nephron epithelium is_a: UBERON:0005103 ! mesonephric epithelium intersection_of: UBERON:0004211 ! nephron epithelium intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0005322 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! mesonephric nephron [Term] id: UBERON:0005331 name: mesonephric renal vesicle namespace: uberon def: "The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO]." [GO:0061243] synonym: "mesonephric vesicle" EXACT [] xref: SCTID:361407006 xref: ZFA:0005586 is_a: UBERON:0004209 ! renal vesicle is_a: UBERON:0005103 ! mesonephric epithelium intersection_of: UBERON:0004209 ! renal vesicle intersection_of: part_of UBERON:0000080 ! mesonephros relationship: develops_from UBERON:0010534 {source="ZFA"} ! primitive mesonephric nephron relationship: has_potential_to_develop_into UBERON:0005330 ! mesonephric nephron epithelium [Term] id: UBERON:0005334 name: oral lamina propria namespace: uberon def: "A lamina propria that is part of a mucosa of oral region." [OBOL:automatic] synonym: "lamina propria of oral mucosa" EXACT [] xref: EMAPA:26947 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000030 ! lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0003343 ! mucosa of oral region relationship: part_of UBERON:0003343 ! mucosa of oral region [Term] id: UBERON:0005337 name: outflow tract of ventricle namespace: uberon def: "A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]." [Wikipedia:Ventricular_outflow_tract] synonym: "heart ventricle outflow tract" EXACT [MP:0010224] synonym: "outflow part of ventricle" EXACT [] synonym: "ventricular outflow tract" EXACT [Wikipedia:Ventricular_outflow_tract] xref: FMA:13225 xref: Wikipedia:Ventricular_outflow_tract xref: XAO:0004140 is_a: UBERON:0004145 ! outflow tract intersection_of: UBERON:0004145 ! outflow tract intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002082 ! cardiac ventricle [Term] id: UBERON:0005338 name: outflow tract aortic component namespace: uberon def: "An outflow tract that is part of a aorta." [OBOL:automatic] xref: EHDAA2:0001353 xref: EMAPA:17329 xref: MA:0000101 xref: VHOG:0001394 is_a: UBERON:0004145 ! outflow tract intersection_of: UBERON:0004145 ! outflow tract intersection_of: part_of UBERON:0000947 ! aorta relationship: part_of UBERON:0000947 ! aorta property_value: editor_note "merge with LVOT?" xsd:string [Term] id: UBERON:0005339 name: outflow tract pulmonary component namespace: uberon xref: EHDAA2:0001359 xref: EHDAA:4401 xref: EMAPA:17330 xref: MA:0000102 xref: VHOG:0001395 is_a: UBERON:0004145 ! outflow tract property_value: editor_note "merge with RVOT?" xsd:string [Term] id: UBERON:0005343 name: cortical plate namespace: uberon def: "The outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers[MP]." [http://www.ncbi.nlm.nih.gov/books/NBK10047, MP:0008439] subset: pheno_slim synonym: "cerebral cortex cortical plate" EXACT [] synonym: "CP" BROAD ABBREVIATION [BRAINSPAN:BRAINSPAN] synonym: "CxP" BROAD ABBREVIATION [PMID:23375746] synonym: "future cortical layers II-VI" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "future neocortex" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "neocortex cortical plate" EXACT [] xref: BAMS:CTXpl xref: DHBA:10515 xref: EMAPA:32711 xref: MBA:695 xref: neuronames:2702 xref: PBA:294021914 is_a: UBERON:0014950 ! layer of developing cerebral cortex relationship: has_potential_to_develop_into UBERON:0001950 {source="NCBIBook:NBK10047"} ! neocortex property_value: UBPROP:0000011 "A single stem cell in the ventricular layer can give rise to neurons (and glial cells) in any of the cortical layers (Walsh and Cepko 1988)[NCBIBook:NBK10047]" xsd:string property_value: UBPROP:0000011 "in humans develops into cortical layers II-VI" xsd:string [Term] id: UBERON:0005352 name: spermatic cord namespace: uberon def: "The cord-like structure in males comprising the vas deferens and associated tissue that runs from the abdomen down to each testis[MP]." [MP:0010145, Wikipedia:Spermatic_cord] subset: pheno_slim synonym: "funiculus spermaticus" RELATED LATIN [Wikipedia:Spermatic_cord] synonym: "spermatic chord" RELATED [] xref: FMA:19937 xref: GAID:395 xref: MESH:D013085 xref: NCIT:C12329 xref: SCTID:181433005 xref: UMLS:C0037855 {source="ncithesaurus:Spermatic_Cord"} xref: Wikipedia:Spermatic_cord is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0034921 ! multi organ part structure relationship: contributes_to_morphology_of UBERON:0004054 ! internal male genitalia relationship: has_part UBERON:0001000 ! vas deferens relationship: part_of UBERON:0004054 ! internal male genitalia property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/35/Male_anatomy.png" xsd:anyURI [Term] id: UBERON:0005362 name: vagus X ganglion namespace: uberon def: "The group of sensory neuron cell bodies associated with the vagus nerve." [ISBN:0-683-40008-8, MP:0001100] subset: pheno_slim synonym: "ganglion of vagus nerve" EXACT [FMA:53472] synonym: "gX" BROAD [ZFA:0007067] synonym: "right glossopharyngeal ganglion" EXACT [FMA:53472] synonym: "vagal ganglion" EXACT [ZFA:0007067] synonym: "vagus ganglion" EXACT [] synonym: "vagus neural ganglion" EXACT [FMA:53472] synonym: "vagus X" RELATED [EMAPA:16798] xref: EMAPA:16798 xref: FMA:53472 xref: MA:0001081 xref: SCTID:244452001 xref: TAO:0007067 xref: VHOG:0000684 xref: Wikipedia:Vagus_ganglion xref: ZFA:0007067 is_a: UBERON:0009127 {source="ZFA"} ! epibranchial ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: extends_fibers_into UBERON:0001759 ! vagus nerve relationship: extends_fibers_into UBERON:0001759 ! vagus nerve [Term] id: UBERON:0005384 name: nasal cavity epithelium namespace: uberon def: "An epithelium that lines the nasal cavity." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "nasal epithelium" EXACT [FMA:63140] synonym: "nasal mucosa" RELATED [MA:0001324] xref: CALOHA:TS-0656 xref: EHDAA2:0001227 xref: EHDAA:6803 xref: EMAPA:17605 xref: FMA:63140 xref: MA:0001324 xref: NCIT:C49261 xref: UMLS:C1709151 {source="ncithesaurus:Nasal_Cavity_Epithelium"} xref: VHOG:0000501 is_a: UBERON:0003350 ! epithelium of mucosa is_a: UBERON:0004814 ! upper respiratory tract epithelium is_a: UBERON:0019306 ! nose epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001826 ! nasal cavity mucosa relationship: bounding_layer_of UBERON:0015788 ! olfactory apparatus chamber relationship: contributes_to_morphology_of UBERON:0000004 ! nose relationship: contributes_to_morphology_of UBERON:0004785 ! respiratory system mucosa relationship: part_of UBERON:0001826 ! nasal cavity mucosa property_value: editor_note "this class may in future be split into the embryonic precursor of the oronasal membrane and the structure that is part of the mucosa in the developed organism" xsd:string [Term] id: UBERON:0005388 name: photoreceptor array namespace: uberon def: "An array of photoreceptors and any supporting cells found in an eye." [https://orcid.org/0000-0002-6601-2165] synonym: "light-sensitive tissue" EXACT [] xref: FBbt:00004200 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of CL:0000210 ! photoreceptor cell intersection_of: part_of UBERON:0000970 ! eye relationship: composed_primarily_of CL:0000210 ! photoreceptor cell relationship: part_of UBERON:0000970 ! eye relationship: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0005389 name: transparent eye structure namespace: uberon def: "A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "lens" NARROW [] is_a: UBERON:0000061 ! anatomical structure relationship: has_quality PATO:0000964 ! transparent relationship: part_of UBERON:0000970 ! eye property_value: UBPROP:0000009 "directing or focusing light onto light receptors" xsd:string [Term] id: UBERON:0005396 name: carotid artery segment namespace: uberon def: "One of: the common carotid artery, or its branches, the external and internal carotid arteries." [https://sourceforge.net/tracker/?func=detail&aid=3486870&group_id=76834&atid=994764, Wikipedia:Carotid_artery] subset: efo_slim subset: grouping_class subset: pheno_slim subset: vertebrate_core synonym: "carotid" EXACT [AAO:0010217] synonym: "carotid artery" EXACT [MA:0001925] synonym: "common carotid arterial subdivision" RELATED [FMA:70504] synonym: "subdivision of common carotid artery" EXACT [FMA:70504] xref: AAO:0010217 xref: BTO:0000168 xref: CALOHA:TS-0116 xref: EFO:0000818 xref: EHDAA:6385 xref: EMAPA:18609 xref: EV:0100379 xref: FMA:70504 xref: GAID:478 xref: galen:CarotidArtery xref: MA:0001925 xref: MAT:0000501 xref: MESH:D002339 xref: NCIT:C12687 xref: SCTID:362040006 xref: SCTID:69105007 xref: TAO:0000097 xref: UMLS:C0007272 {source="ncithesaurus:Carotid_Artery"} xref: VHOG:0000266 xref: Wikipedia:Carotid_artery xref: ZFA:0000097 is_a: UBERON:0004573 {source="FMA"} ! systemic artery property_value: editor_note "This is a generic grouping class that is the superclass of the trunks/branches of the common carotid artery. Note that AOs vary widely in how they divide up and generalize arteries" xsd:string property_value: UBPROP:0000001 "Artery originating at the junction of the first two aortic arches and supplying the anterior brain. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000097", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005398 name: female reproductive gland namespace: uberon def: "A sex gland that is part of a female reproductive system." [OBOL:automatic] subset: organ_slim subset: pheno_slim xref: BTO:0000254 xref: MA:0000383 is_a: UBERON:0003937 ! reproductive gland intersection_of: UBERON:0003937 ! reproductive gland intersection_of: part_of UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0003134 ! female reproductive organ [Term] id: UBERON:0005399 name: male reproductive gland namespace: uberon def: "A sex gland that is part of a male reproductive system." [OBOL:automatic] subset: organ_slim subset: pheno_slim synonym: "accessory sex gland" RELATED [EMAPA:19285] xref: BTO:0000080 xref: EMAPA:19285 xref: MA:0000399 is_a: UBERON:0003937 ! reproductive gland intersection_of: UBERON:0003937 ! reproductive gland intersection_of: part_of UBERON:0000079 ! male reproductive system relationship: part_of UBERON:0000079 ! male reproductive system [Term] id: UBERON:0005401 name: cerebral hemisphere gray matter namespace: uberon def: "A gray matter that is part of a cerebral hemisphere." [OBOL:automatic] synonym: "cerebral gray matter" EXACT [BTO:0000823] synonym: "cerebral grey matter" EXACT [MA:0000944] synonym: "cerebral hemisphere grey matter" EXACT [] xref: BTO:0000823 xref: CALOHA:TS-2361 xref: EMAPA:37477 {source="MA:th"} xref: FMA:61821 xref: MA:0000944 is_a: UBERON:0011300 ! gray matter of telencephalon intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0001869 ! cerebral hemisphere property_value: UBPROP:0000012 "BTO may actually be a more generic structure; FMA may represent a more specific structure. Consider merging with gray matter of telencephalon" xsd:string {external_ontology="BTO"} [Term] id: UBERON:0005404 name: frontonasal suture namespace: uberon def: "A suture between frontal and nasal bones." [GO:0097095, PMID:12416537] subset: pheno_slim synonym: "articulation of the nasal bone with frontal bone" RELATED [] synonym: "frontonasal suture of skull" EXACT [FMA:52948] xref: EMAPA:35359 xref: FMA:52948 xref: MA:0002973 xref: SCTID:368982004 is_a: UBERON:0009198 ! craniofacial suture intersection_of: UBERON:0009198 ! craniofacial suture intersection_of: connects UBERON:0000209 ! tetrapod frontal bone intersection_of: connects UBERON:0001681 ! nasal bone relationship: connects UBERON:0000209 ! tetrapod frontal bone relationship: connects UBERON:0001681 ! nasal bone [Term] id: UBERON:0005409 name: alimentary part of gastrointestinal system namespace: uberon def: "The part of the digestive system that excludes the hepatobiliary system." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "alimentary system" RELATED [MA:0000323] synonym: "alimentary tract" RELATED [MA:0000323] synonym: "gastro-intestinal system" RELATED [FMA:71132] synonym: "gastroenterological system" RELATED [UBERON:cjm] synonym: "gastrointestinal (GI) tract" RELATED [GAID:294] synonym: "gastrointestinal system" RELATED [FMA:71132] synonym: "gastrointestinal tract" RELATED INCONSISTENT [FMA:71132] synonym: "GI tract" RELATED [GAID:294] xref: BTO:0000058 xref: CALOHA:TS-0407 xref: EHDAA2:0000110 xref: EHDAA:514 xref: EMAPA:16246 xref: EV:0100056 xref: FMA:71132 xref: GAID:294 xref: galen:GastrointestinalTract xref: MA:0000323 xref: MESH:D041981 xref: NCIT:C12378 xref: SCTID:373871007 xref: UMLS:C0012240 {source="ncithesaurus:Gastrointestinal_System"} xref: VHOG:0000412 is_a: UBERON:0000467 ! anatomical system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: part_of UBERON:0001007 ! digestive system property_value: editor_note "the decision to split digestive and gastrointestinal in this way may be revisited. As it currently stands, this class more closely aligns what MA calls the alimentary system" xsd:string property_value: UBPROP:0000001 "The system that includes the esophagus, stomach, small and large intestine, anus, liver, biliary tract, and pancreas[ncithesaurus:Gastrointestinal_System]." xsd:string {source="ncithesaurus:Gastrointestinal_System"} property_value: UBPROP:0000003 "All metazoans (with degenerate exceptions) have some sort of digestive cavity with a means of entrance to and exit from it.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000412", ontology="VHOG", source="ISBN:978-0721676685 Sherwood Romer A and Parsons T, Vertebrate body (1977) p.3", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "that many anatomy ontologies consider this synonymous with digestive system. here we follow MA in dividing digestive system into gastrointestinal and hepatobiliary. hepatobiliary includes the liver and biliary tract. species-specific AO classes are categorized according to whether liver is included. For example, XAO includes liver as part of XAO:0000125 alimentary system, so we assume this class is the more generic class. We have one entity that is part of both gastrointestinal and hepatobiliary systems: hepatopancreatic ampulla." xsd:string {external_ontology="MA"} [Term] id: UBERON:0005417 name: forelimb bud namespace: uberon def: "A limb bud that develops into a forelimb." [http://orcid.org/0000-0002-6601-2165] comment: Genes: Tbx5 specifies forelimbs. Wnt2b restricts Fgf10 in chick // In tetrapods, the position of the forelimb is associated with the anterior expression border of Hoxc6 in the paraxial mesoderm (Burke et al., 1995) subset: pheno_slim synonym: "anterior limb bud" EXACT [] synonym: "arm bud" RELATED [] synonym: "limb bud - forelimb" EXACT [MIAA:0000065] synonym: "upper limb bud" EXACT [RETIRED_EHDAA2:0003198] synonym: "wing bud" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: AAO:0010381 xref: BTO:0001645 xref: EHDAA:1699 xref: EMAPA:16406 xref: FMA:296782 xref: MIAA:0000065 xref: RETIRED_EHDAA2:0003198 xref: SCTID:346062002 xref: XAO:0003065 is_a: UBERON:0004347 ! limb bud is_a: UBERON:0005419 ! pectoral appendage bud intersection_of: UBERON:0004347 ! limb bud intersection_of: has_potential_to_develop_into UBERON:0002102 ! forelimb disjoint_from: UBERON:0005418 {source="lexical"} ! hindlimb bud relationship: has_potential_to_develop_into UBERON:0002102 ! forelimb [Term] id: UBERON:0005418 name: hindlimb bud namespace: uberon def: "A limb bud that develops into a hindlimb." [http://orcid.org/0000-0002-6601-2165] comment: Genes: Tbx4 specifies hindlimbs. Wnt8c restricts Fgf10 in chick. subset: pheno_slim synonym: "hind limb bud" EXACT [XAO:0003066] synonym: "leg bud" RELATED [] synonym: "limb bud - hindlimb" RELATED [] synonym: "posterior limb bud" EXACT [] xref: AAO:0010382 xref: EHDAA:2358 xref: EMAPA:16779 xref: MIAA:0000256 xref: RETIRED_EHDAA2:0003197 xref: SCTID:346164003 xref: XAO:0003066 is_a: UBERON:0004347 ! limb bud is_a: UBERON:0005420 ! pelvic appendage bud intersection_of: UBERON:0004347 ! limb bud intersection_of: has_potential_to_develop_into UBERON:0002103 ! hindlimb intersection_of: part_of UBERON:0000154 ! posterior region of body relationship: has_potential_to_develop_into UBERON:0002103 ! hindlimb property_value: UBPROP:0000001 "The bilateral thickening of the ectoderm in the region of the first noticeable at NF stage 47, and innervated by NF stage 51. The hind limb buds develop before the forelimb buds.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010382", ontology="AAO", source="XAO:curator"} [Term] id: UBERON:0005419 name: pectoral appendage bud namespace: uberon def: "A limb bud that develops into a forelimb or pectoral fin." [OBOL:automatic] comment: at this time we have no need to name a more specific 'pectoral fin bud' class, but we may in future subset: efo_slim synonym: "forelimb - pectoral fin bud" EXACT [VHOG:0001754] synonym: "pectoral fin bud" RELATED [TAO:0000141] synonym: "pectoral fin buds" RELATED PLURAL [TAO:0000141] xref: EFO:0003430 xref: TAO:0000141 xref: VHOG:0001754 xref: VHOG_RETIRED:0001259 xref: ZFA:0000141 is_a: UBERON:0004357 ! paired limb/fin bud intersection_of: UBERON:0004357 ! paired limb/fin bud intersection_of: has_potential_to_develop_into UBERON:0004710 ! pectoral appendage relationship: has_developmental_contribution_from UBERON:0005729 ! pectoral appendage field relationship: has_potential_to_develop_into UBERON:0004710 ! pectoral appendage relationship: part_of UBERON:0000153 ! anterior region of body property_value: UBPROP:0000001 "Fin bud that develops into the pectoral fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000141", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "While the skeletons of teleost pectoral fins and tetrapod forelimbs are homologous at the level of endoskeletal radials, teleosts and tetrapods do not share homologous skeletal elements at the level of 'individuated' pro-, meso-, and metapterygia. Among osteichthyans, only basal actinopterygians retain the full complement of elements present in non-osteichthyan gnathostomes.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001754", ontology="VHOG", source="DOI:10.1002/jmor.10264 Davis MC, Shubin NH, Force A, Pectoral fin and girdle development in the basal actinopterygians Polyodon spathula and Acipenser transmontanus. Journal of Morphology (2004)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005420 name: pelvic appendage bud namespace: uberon def: "A limb bud that develops into a hindlimb or pelvic fin." [OBOL:automatic] comment: at this time we have no need to name a more specific 'pelvic fin bud' class, but we may in future subset: efo_slim synonym: "hindlimb/pelvic fin bud" EXACT [VHOG:0001260] synonym: "pelvic fin bud" RELATED [TAO:0001384] synonym: "pelvic fin buds" RELATED PLURAL [ZFA:0001384] xref: EFO:0003469 xref: TAO:0001384 xref: VHOG:0001260 xref: ZFA:0001384 is_a: UBERON:0004357 ! paired limb/fin bud intersection_of: UBERON:0004357 ! paired limb/fin bud intersection_of: has_potential_to_develop_into UBERON:0004709 ! pelvic appendage intersection_of: part_of UBERON:0000154 ! posterior region of body relationship: has_developmental_contribution_from UBERON:0005730 ! pelvic appendage field relationship: has_potential_to_develop_into UBERON:0004709 ! pelvic appendage relationship: part_of UBERON:0000154 ! posterior region of body property_value: RO:0002161 NCBITaxon:31033 {source="PMID:15893975"} property_value: UBPROP:0000001 "Fin bud that develops into the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001384", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Most anatomists now agree that the three proximal bones of the tetrapod limbs are homologous to the two or three proximal elements of the paired fin skeleton of other sarcopterygians, that is the humerus-femur, radius-tibia, and ulna-fibula.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001260", ontology="VHOG", source="ISBN:978-0198540472 Janvier P, Early vertebrates (1996) p.268", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005421 name: pectoral appendage apical ectodermal ridge namespace: uberon def: "An apical ectodermal ridge that is part of a pectoral appendage bud." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "AER forelimb" NARROW [VHOG:0001064] synonym: "aer pectoral fin" RELATED [TAO:0000085] synonym: "apical ectodermal ridge forelimb" NARROW [VHOG:0001064] synonym: "apical ectodermal ridge pectoral fin" RELATED [TAO:0000085] synonym: "apical ectodermal ridge pectoral fin bud" NARROW [ZFA:0000085] synonym: "apical fold pectoral fin" RELATED [TAO:0000085] synonym: "upper limb bud apical ectodermal ridge" NARROW [EHDAA2:0000138] synonym: "wing AER" NARROW SENSU [Giesha:syn] synonym: "wing apical ectodermal ridge" NARROW SENSU [] xref: EFO:0003487 xref: EHDAA2:0000138 xref: EMAPA:16778 xref: TAO:0000085 xref: TAO:0000736 xref: VHOG:0001064 xref: ZFA:0000085 is_a: UBERON:0004356 ! apical ectodermal ridge intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0005419 ! pectoral appendage bud relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0005419 ! pectoral appendage bud property_value: UBPROP:0000001 "An ectodermal thickening at the end of the forelimb bud in the developing embryo. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001064", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/apical+ectodermal+ridge"} property_value: UBPROP:0000001 "Apical ectodermal ridge that is part of the pectoral fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000085", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "Pectoral and pelvic fins are homologous to the tetrapod fore and hindlimb, respectively. (...) The zebrafish AER [apical ectodermal ridge] is an apical ectodermal thickening at the distal tip of the fin bud and consists of wedge-shaped cells of the basal stratum. The AER is observed only transiently, and from 36 hpf onwards the cells of this region form the apical fold (AF), which consists of a dorsal and a ventral layer of cylindrically-shaped ectodermal cells extending from the anterior to the posterior fin margin. Despite the change in shape, the AF still carries out the same functions as the AER. Indeed, although the AER receives its name from its characteristic shape, being composed of a pseudostratified ectoderm in the chicken and a polystratified ectoderm in the mouse, this independence of AER morphology from its function is also observed in tetrapods. The AF also expresses similar molecular markers to the tetrapod AER, suggesting that it fulfills similar functions in the fin as the AER does in tetrapod limbs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001064", ontology="VHOG", source="DOI:10.1111/j.1440-169X.2007.00942.x", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005422 name: pelvic appendage apical ectodermal ridge namespace: uberon def: "An apical ectodermal ridge that is part of a pelvic appendage bud." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "AER hindlimb" RELATED [VHOG:0001066] synonym: "apical ectodermal ridge hind limb" NARROW [VHOG:0001066] synonym: "apical ectodermal ridge hindlimb" NARROW [VHOG:0001066] synonym: "apical ectodermal ridge pelvic fin bud" RELATED [TAO:0001385] synonym: "leg AER" RELATED [] synonym: "lower lmb bud apical ectodermal ridge" NARROW [EHDAA2:0003194] xref: EFO:0003681 xref: EHDAA2:0003194 xref: EMAPA:16892 xref: TAO:0001385 xref: VHOG:0001066 xref: ZFA:0001385 is_a: UBERON:0004356 ! apical ectodermal ridge intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0005420 ! pelvic appendage bud relationship: develops_from UBERON:0003371 {source="EHDAA2"} ! pelvic appendage bud ectoderm relationship: part_of UBERON:0005420 ! pelvic appendage bud property_value: UBPROP:0000001 "An ectodermal thickening at the end of the hindlimb bud in the developing embryo. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001066", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/apical+ectodermal+ridge"} property_value: UBPROP:0000001 "Apical ectodermal ridge that is part of the pelvic fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001385", ontology="TAO", source="ZIFIN:curator"} property_value: UBPROP:0000003 "Pectoral and pelvic fins are homologous to the tetrapod fore and hindlimb, respectively. (...) The zebrafish AER [apical ectodermal ridge] is an apical ectodermal thickening at the distal tip of the fin bud and consists of wedge-shaped cells of the basal stratum. The AER is observed only transiently, and from 36 hpf onwards the cells of this region form the apical fold (AF), which consists of a dorsal and a ventral layer of cylindrically-shaped ectodermal cells extending from the anterior to the posterior fin margin. Despite the change in shape, the AF still carries out the same functions as the AER. Indeed, although the AER receives its name from its characteristic shape, being composed of a pseudostratified ectoderm in the chicken and a polystratified ectoderm in the mouse, this independence of AER morphology from its function is also observed in tetrapods. The AF also expresses similar molecular markers to the tetrapod AER, suggesting that it fulfills similar functions in the fin as the AER does in tetrapod limbs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001066", ontology="VHOG", source="DOI:10.1111/j.1440-169X.2007.00942.x", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005423 name: developing anatomical structure namespace: uberon subset: common_anatomy synonym: "developing structure" RELATED [] synonym: "developmental structure" RELATED [] synonym: "developmental tissue" RELATED [MIAA:0000019] xref: AEO:0000125 xref: CALOHA:TS-2122 xref: EHDAA2:0003125 xref: FBbt:00007006 xref: FMA:292313 xref: MIAA:0000019 is_a: UBERON:0000465 ! material anatomical entity relationship: capable_of GO:0032502 ! developmental process property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0005425 name: presumptive neural retina namespace: uberon def: "Portion of tissue that is the inner layer of the optic cup and will become the neural retina." [ZFIN:curator] subset: vertebrate_core synonym: "future neural epithelium" RELATED [EMAPA:16675] synonym: "future neural layer" RELATED [EMAPA:16675] synonym: "future neural retina" EXACT [] synonym: "future NR" RELATED [] synonym: "future retinal neural layer" EXACT [] synonym: "inner layer optic cup" EXACT [ZFA:0001071] synonym: "optic cup inner layer" EXACT [EHDAA2:0001304] synonym: "presumptive retina" RELATED [TAO:0001071] synonym: "presumptive retinas" EXACT PLURAL [ZFA:0001071] xref: EHDAA2:0001304 xref: EMAPA:16675 xref: TAO:0001071 xref: VHOG:0000490 xref: ZFA:0001071 is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0010312 ! immature eye intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0003902 ! retinal neural layer relationship: has_potential_to_develop_into UBERON:0003902 ! retinal neural layer relationship: part_of UBERON:0003072 ! optic cup property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The outer layer of the optic cup becomes the pigment layer of the retina, whereas the inner layer differentiates into the photoreceptive cells and neuronal layers of the retina.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000490", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005426 name: lens vesicle namespace: uberon def: "Portion of tissue that gives rise to the lens." [https://sourceforge.net/tracker/?func=detail&atid=994726&aid=3514998&group_id=76834, ZFIN:curator] subset: pheno_slim subset: vertebrate_core synonym: "hollow lens vesicle" NARROW SENSU [] synonym: "immature lens" RELATED [ZFA:0001679] synonym: "lens mass" RELATED [ZFA:0001679, ZFIN:ZDB-PUB-091023-49] synonym: "presumptive lens" RELATED [ZFA:0001679] synonym: "solid lens vesicle" NARROW SENSU [ZFA:0001679] xref: EHDAA2:0000983 xref: EHDAA:4737 xref: EMAPA:17163 xref: SCTID:361510002 xref: TAO:0002205 xref: VHOG:0001163 xref: ZFA:0001679 is_a: UBERON:0000479 ! tissue is_a: UBERON:0004121 ! ectoderm-derived structure relationship: develops_from UBERON:0003073 ! lens placode relationship: has_quality PATO:0001736 {gci_relation="part_of", gci_filler="NCBITaxon:32443", notes="teleosts"} ! solid configuration relationship: has_quality PATO:0002078 {gci_relation="part_of", gci_filler="NCBITaxon:40674", notes="Mammals"} ! hollow property_value: UBPROP:0000001 "A vesicle formed from the lens pit of the embryo, developing into the crystalline lens. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001163", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/lens+vesicle"} property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001163", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "the lens of zebrafish (and other teleosts) forms from delamination of cells from the lens placode; thus, there is no formation of a hollow lens vesicle, in contrast to the situation in mammals and birds (Glass and Dahm, 2004) [PMID:16496288] The lens of the zebrafish forms by delamination of lens placodal cells and not through invagination. This results in a solid spherical mass as opposed to a hollow lens vesicle. Detachment of the solid lens vesicle of zebrafish at 24b26 hpf is accomplished in part by apoptosis, similar to mammals" xsd:string {source="ZFA"} [Term] id: UBERON:0005427 name: corneal primordium namespace: uberon def: "Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea." [ZFIN:ZDB-PUB-061010-3] xref: TAO:0002188 xref: ZFA:0001688 is_a: UBERON:0000479 {source="ZFA"} ! tissue is_a: UBERON:0001048 {source="Obol"} ! primordium is_a: UBERON:0010312 ! immature eye is_a: UBERON:0010313 ! neural crest-derived structure relationship: part_of UBERON:0000019 {source="ZFA"} ! camera-type eye [Term] id: UBERON:0005428 name: vagal neural crest namespace: uberon def: "Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]." [ZFIN:curator] subset: vertebrate_core synonym: "enteric neural crest" RELATED [] synonym: "post-otic neural crest" RELATED [ZFA:0000818] synonym: "VNC" EXACT ABBREVIATION [XAO:0004191] xref: EHDAA2:0002156 xref: EHDAA:669 xref: TAO:0000818 xref: VHOG:0001208 xref: XAO:0004191 xref: ZFA:0000818 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0002342 ! neural crest property_value: UBPROP:0000001 "Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000818", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001208", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "In chicken fate mapping studies it was found to originate from neural crest residing between Somite 1-7 (S1-7); In mouse it is considered to be derived from rhombencephalic (post otic) neural crest cells and trunk neural crest cells (anterior to S5)" xsd:string {source="filemaps.com"} [Term] id: UBERON:0005432 name: aortic sac namespace: uberon def: "The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates." [MP:0012510] subset: pheno_slim synonym: "saccus aorticus" EXACT LATIN [] xref: EHDAA2:0004145 xref: EHDAA:9826 xref: EMAPA:36461 xref: FMA:71008 xref: RETIRED_EHDAA2:0000133 xref: SCTID:361527005 is_a: UBERON:0001637 {source="EHDAA2"} ! artery is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0003498 ! heart blood vessel relationship: develops_from UBERON:0004363 {source="EHDAA2"} ! pharyngeal arch artery relationship: part_of UBERON:0004145 ! outflow tract property_value: UBPROP:0000001 "the merged ventral aortae of the embryo which supplies blood to the aortic arches[TMD][http://medical-dictionary.thefreedictionary.com/aortic+sac]." xsd:string {source="http://medical-dictionary.thefreedictionary.com/aortic+sac"} [Term] id: UBERON:0005434 name: cervical region namespace: uberon synonym: "cervical region" EXACT [FMA:24219] synonym: "neck subdivision" EXACT [FMA:24219] synonym: "region of neck" EXACT [FMA:24219] synonym: "subdivision of neck" EXACT [FMA:24219] xref: FMA:24219 xref: SCTID:123958008 is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: only_in_taxon NCBITaxon:8287 ! Sarcopterygii relationship: part_of UBERON:0000974 ! neck [Term] id: UBERON:0005436 name: common hepatic artery namespace: uberon def: "In anatomy, the common hepatic artery is a short blood vessel that supplies oxygenated blood to the liver, pylorus (a part of the stomach), duodenum (a part of the small intestine) and pancreas. It arises from the celiac artery and has the following branches:." [Wikipedia:Common_hepatic_artery] subset: human_reference_atlas synonym: "arteria hepatica communis" RELATED LATIN [Wikipedia:Common_hepatic_artery] synonym: "common hepatic" RELATED [Wikipedia:Common_hepatic_artery] xref: EHDAA2:0000308 xref: EHDAA:8570 xref: EMAPA:37206 {source="MA:th"} xref: FMA:14771 xref: galen:CommonHepaticArtery xref: MA:0003094 xref: SCTID:244263001 xref: Wikipedia:Common_hepatic_artery is_a: UBERON:0004573 ! systemic artery relationship: branching_part_of UBERON:0001640 ! celiac artery relationship: part_of UBERON:0001640 ! celiac artery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/65/Gray532.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0005445 name: segment of pes namespace: uberon def: "A segment of autopod that is part of a pes." [OBOL:automatic] subset: pheno_slim synonym: "foot region" BROAD [FMA:24993] synonym: "foot subdivision" EXACT [FMA:24993] synonym: "regio pedis" EXACT LATIN [FMA:24993, FMA:TA] synonym: "segment of foot" EXACT [FMA:24993] synonym: "subdivision of foot" EXACT [FMA:24993] xref: FMA:24993 xref: SCTID:362887000 is_a: UBERON:0008784 ! lower limb segment is_a: UBERON:0012139 ! segment of autopod intersection_of: UBERON:0012139 ! segment of autopod intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0002387 ! pes [Term] id: UBERON:0005446 name: foramen rotundum namespace: uberon def: "The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa." [Wikipedia:Foramen_rotundum] synonym: "foramen rotundum of the skull" RELATED [Wikipedia:Foramen_rotundum] synonym: "foramen rotundum ossis sphenoidalis" RELATED LATIN [Wikipedia:Foramen_rotundum] synonym: "round foramen" RELATED [VHOG:0001543] xref: AAO:0000194 xref: EHDAA2:0000552 xref: EHDAA:10629 xref: EMAPA:18712 xref: FMA:53154 xref: SCTID:369439002 xref: VHOG:0001543 xref: Wikipedia:Foramen_rotundum is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: conduit_for UBERON:0000377 ! maxillary nerve intersection_of: part_of UBERON:0001677 ! sphenoid bone relationship: conduit_for UBERON:0000377 ! maxillary nerve relationship: part_of UBERON:0001677 ! sphenoid bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/35/Gray145.png" xsd:anyURI property_value: UBPROP:0000001 "A circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa.vity. [Wikipedia:Foramen_rotundum][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001543", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "It is suggested that the mammalian lamina ascendens arose from an upgrowth of the root of the quadrate ramus of the epipterygoid in cynodonts, separating foramen rotundum from foramen ovale.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001543", ontology="VHOG", source="PMID:1018003 Presley R, Steel FLD, On the homology of the alisphenoid. Journal of Anatomy (1976)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "todo - check placement of AAO class" xsd:string {external_ontology="AAO"} [Term] id: UBERON:0005451 name: segment of manus namespace: uberon def: "A segment of autopod that is part of a manus." [OBOL:automatic] subset: pheno_slim synonym: "hand region" BROAD [FMA:24945] synonym: "hand subdivision" EXACT [FMA:24945] synonym: "regio manus" EXACT LATIN [] synonym: "segment of hand" EXACT [FMA:24945] synonym: "subdivision of hand" EXACT [FMA:24945] xref: FMA:24945 xref: SCTID:127950000 is_a: UBERON:0008785 ! upper limb segment is_a: UBERON:0012139 ! segment of autopod intersection_of: UBERON:0012139 ! segment of autopod intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0002398 ! manus [Term] id: UBERON:0005456 name: jugular foramen namespace: uberon def: "The jugular foramen is a large aperture in the base of the skull. It is located behind the carotid canal and is formed in front by the petrous portion of the temporal, and behind by the occipital; it is generally larger on the right than on the left side." [Wikipedia:Jugular_foramen] synonym: "foramen jugulare" RELATED [Wikipedia:Jugular_foramen] synonym: "Posterior lacerate foramen" EXACT [FMA:56432] xref: AAO:0000249 xref: EHDAA2:0000893 xref: EHDAA:10631 xref: EMAPA:18713 xref: FMA:56432 xref: MESH:D000080869 xref: NCIT:C12496 xref: SCTID:361735006 xref: UMLS:C0222712 {source="ncithesaurus:Jugular_Foramen"} xref: VHOG:0001113 xref: Wikipedia:Jugular_foramen is_a: UBERON:0018321 ! foramen for glossopharyngeal nerve intersection_of: UBERON:0013685 ! foramen of skull intersection_of: conduit_for UBERON:0001586 ! internal jugular vein intersection_of: part_of UBERON:0001678 ! temporal bone relationship: conduit_for UBERON:0001586 ! internal jugular vein relationship: conduit_for UBERON:0001759 ! vagus nerve relationship: conduit_for UBERON:0002019 ! accessory XI nerve relationship: part_of UBERON:0001678 ! temporal bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/fa/Foramenjugulare.PNG" xsd:anyURI property_value: UBPROP:0000001 "Large foramen that houses the glossopharyngeal and vagus nerves and is located inside the condyloid fossa.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000249", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "One of a pair of openings between the lateral part of the occipital bone and the petrous part of the temporal bones in the skull. The foramen contains the inferior petrosal sinus; the transverse sinus; some meningeal branches of the occipital and ascending pharyngeal arteries; and the glossopharyngeal, vagus, and accessory nerves. [Free_Online_Medical_Dictionary]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001113", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/jugular+foramen"} property_value: UBPROP:0000002 "relationship loss: subclass braincase and otic capsule opening (AAO:0000051)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000249", ontology="AAO"} [Term] id: UBERON:0005458 name: left umbilical artery namespace: uberon synonym: "embryonic left umbilical artery" EXACT [VHOG:0000522] xref: EHDAA2:0000966 xref: EMAPA:16544 xref: FMA:18822 xref: VHOG:0000522 is_a: UBERON:0001310 ! umbilical artery relationship: develops_from UBERON:0005613 {notes="check this", source="EHDAA2"} ! left dorsal aorta relationship: develops_from UBERON:0011696 {notes="check this", source="EHDAA2"} ! left extraembryonic umbilical artery [Term] id: UBERON:0005460 name: left vitelline vein namespace: uberon def: "A vitelline vein that is in the left side of a multicellular organism." [OBOL:automatic] xref: EHDAA2:0000971 xref: EMAPA:16380 xref: EMAPA:16698 xref: FMA:70307 xref: SCTID:361446008 is_a: UBERON:0005487 ! vitelline vein is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0005487 ! vitelline vein intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0005461 name: levator scapulae muscle namespace: uberon def: "An axial muscle that originates in the cervical vertebraae inserts on the scapula." [http://orcid.org/0000-0002-6601-2165] comment: Axial muscle group[Kardong] subset: human_reference_atlas subset: pheno_slim synonym: "levator scapula" RELATED [Wikipedia:Levator_scapulae_muscle] synonym: "levator scapulae" EXACT [FMA:32519] synonym: "levator scapulae muscle" RELATED [Wikipedia:Levator_scapulae_muscle] synonym: "levator scapulæ" RELATED [Wikipedia:Levator_scapulae_muscle] synonym: "musculus levator scapulae" RELATED LATIN [Wikipedia:Levator_scapulae_muscle] xref: AAO:0010689 xref: EHDAA2:0000992 xref: EHDAA:8309 xref: FMA:32519 xref: SCTID:279236008 xref: Wikipedia:Levator_scapulae_muscle is_a: UBERON:0001482 ! muscle of shoulder is_a: UBERON:0003897 ! axial muscle is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004518 ! muscle of vertebral column is_a: UBERON:0034908 ! scapular muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0002413 ! cervical vertebra intersection_of: attaches_to UBERON:0006849 ! scapula relationship: attaches_to UBERON:0002413 ! cervical vertebra relationship: develops_from UBERON:0010983 {source="EHDAA2"} ! levator scapulae pre-muscle mass relationship: has_muscle_insertion UBERON:0007174 {notes="Superior part of medial border of scapula", source="dbpedia"} ! medial border of scapula relationship: has_muscle_origin UBERON:0001077 {notes="Posterior tubercles of transverse processes of C1 - C4 vertebrae", source="dbpedia"} ! transverse process of vertebra relationship: innervated_by UBERON:0000962 {notes="cervical nerve and dorsal scapular nerve", source="dbpedia"} ! nerve of cervical vertebra relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/b/bc/Levator_scapulae.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0005462 name: lower back namespace: uberon def: "Subdivision of abdominal segment of trunk which in humans is demarcated from the front of the abdomen by the posterior surface of the anterior layer of the thoracolumbar fascia and the anterior surface of the lumbar vertebral column; together with the front of the abdomen, it constitutes the abdomen[Modified from FMA]." [FMA:61681] comment: overlaps with region sometimes called 'loin' synonym: "abdominal back" EXACT [FMA:61681] synonym: "back of abdomen" EXACT [FMA:61681] synonym: "dorsum of abdomen" EXACT [FMA:61681] synonym: "loin" RELATED [BTO:0001505, Wikipedia:Loin] synonym: "lombus" RELATED [] synonym: "lower back" EXACT [MA:0000027] synonym: "lumbar part of back" EXACT [FMA:61681] synonym: "lumbar region" BROAD [FMA:61681] synonym: "lumbar region of back" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "lumbos" RELATED [] synonym: "posterior part of abdomen" EXACT [FMA:61681] synonym: "regio lumbalis" EXACT LATIN [FMA:61681, FMA:TA] xref: BTO:0001505 xref: EMAPA:36623 xref: FMA:61681 xref: MA:0000027 xref: NCIT:C34004 xref: SCTID:182343007 xref: UMLS:C0024090 {source="ncithesaurus:Lumbar_Region"} is_a: UBERON:0009569 ! subdivision of trunk relationship: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0002417 {source="MA"} ! abdominal segment of trunk property_value: UBPROP:0000007 "lumbar" xsd:string [Term] id: UBERON:0005465 name: obturator nerve namespace: uberon def: "The obturator nerve arises from the ventral divisions of the second, third, and fourth lumbar nerves; the branch from the third is the largest, while that from the second is often very small." [Wikipedia:Obturator_nerve] synonym: "nervus obturatorius" RELATED LATIN [Wikipedia:Obturator_nerve] xref: EHDAA2:0001282 xref: EHDAA:5657 xref: FMA:16487 xref: MESH:D009776 xref: NCIT:C75909 xref: SCTID:181052006 xref: UMLS:C0028783 {source="ncithesaurus:Obturator_Nerve"} xref: Wikipedia:Obturator_nerve is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001021 ! nerve relationship: innervates UBERON:0000376 ! hindlimb stylopod relationship: part_of UBERON:0001815 ! lumbosacral nerve plexus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b7/Gray344.png" xsd:anyURI [Term] id: UBERON:0005470 name: right umbilical artery namespace: uberon synonym: "embryonic right umbilical artery" EXACT [VHOG:0000523] xref: EHDAA2:0001760 xref: EMAPA:16545 xref: FMA:18821 xref: VHOG:0000523 is_a: UBERON:0001310 ! umbilical artery relationship: develops_from UBERON:0005622 {notes="check this", source="EHDAA2"} ! right dorsal aorta relationship: develops_from UBERON:0011697 {notes="check this", source="EHDAA2"} ! right extraembryonic umbilical artery [Term] id: UBERON:0005472 name: right vitelline vein namespace: uberon def: "A vitelline vein that is in the right side of a multicellular organism." [OBOL:automatic] xref: EHDAA2:0001766 xref: EMAPA:16381 xref: EMAPA:16699 xref: FMA:70306 xref: SCTID:361445007 is_a: UBERON:0005487 ! vitelline vein is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0005487 ! vitelline vein intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0005473 name: sacral region namespace: uberon def: "A subdivision of an organism along the anterior-posterior axis in the pelvic region immediately posterior to the lumbar region and anterior to the caudal region. Sometimes an intermediate region is defined between the sacral and caudal." [http://orcid.org/0000-0002-6601-2165] synonym: "back of pelvis" EXACT [FMA:24228] synonym: "croup" NARROW SENSU [Wikipedia:Rump_(animal)] synonym: "hindquarter" NARROW SENSU [Wikipedia:Rump_(animal)] synonym: "pelvic back" EXACT [FMA:24228] synonym: "posterior part of pelvis" EXACT [FMA:24228] synonym: "regio sacralis" EXACT LATIN [FMA:24228, FMA:TA] synonym: "rump" NARROW SENSU [Wikipedia:Rump_(animal)] synonym: "sacral part of pelvis" EXACT [FMA:24228] xref: FMA:24228 xref: SCTID:182344001 xref: Wikipedia:Sacrum is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: has_skeleton UBERON:0006075 ! sacral region of vertebral column relationship: part_of UBERON:0002355 ! pelvic region of trunk property_value: UBPROP:0000007 "pygal" xsd:string property_value: UBPROP:0000007 "sacral" xsd:string property_value: UBPROP:0000008 "Amphibians - 1 sacral vertebra; Living reptiles & most birds - 2 sacral vertebrae; Most mammals - 3 to 5 sacral vertebrae. TODO - split sacral from sacrococcygeal" xsd:string [Term] id: UBERON:0005478 name: sulcus limitans of neural tube namespace: uberon def: "A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]." [http://medical-dictionary.thefreedictionary.com/Sulcus+limitans, http://www.ncbi.nlm.nih.gov/books/NBK10047] synonym: "neural tube lateral wall sulcus limitans" EXACT [EHDAA2:0001265] synonym: "sulcus limitans" BROAD [] xref: BAMS:slim xref: BAMS:slm xref: neuronames:629 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006846 ! surface groove relationship: part_of UBERON:0005496 {source="EHDAA2"} ! neural tube lateral wall [Term] id: UBERON:0005487 name: vitelline vein namespace: uberon def: "The paired veins that carry blood from the yolk sac back to the embryo." [MGI:csmith, MP:0010666] subset: pheno_slim subset: vertebrate_core synonym: "embryonic vitelline vein" EXACT [VHOG:0000401] synonym: "omphalomesenteric vein" RELATED [EMAPA:16244] synonym: "vascular vitelline network" EXACT [XAO:0004147] synonym: "vein of omphalomesenteric system" RELATED [] synonym: "vena vitellina" EXACT LATIN [Wikipedia:Vitelline_veins] synonym: "vitelline veins" RELATED PLURAL [XAO:0004147] xref: EMAPA:36021 xref: FMA:70305 xref: NCIT:C34329 xref: RETIRED_EHDAA2:0002209 xref: SCTID:2730004 xref: SCTID:308832003 xref: UMLS:C0231091 {source="ncithesaurus:Vitelline_Vein"} xref: VHOG:0000401 xref: Wikipedia:Vitelline_veins xref: XAO:0000376 xref: XAO:0004147 is_a: UBERON:0004365 ! vitelline blood vessel is_a: UBERON:0013140 ! systemic vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001040 ! yolk sac relationship: drains UBERON:0001040 ! yolk sac property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7e/Gray475.png" xsd:anyURI property_value: UBPROP:0000001 "One of two veins that run upward at first in front, and subsequently on either side of the intestinal canal. They unite on the ventral aspect of the canal, and beyond this are connected to one another by two anastomotic branches, one on the dorsal, and the other on the ventral aspect of the duodenal portion of the intestine, which is thus encircled by two venous rings; into the middle or dorsal anastomosis the superior mesenteric vein opens. The portions of the veins above the upper ring become interrupted by the developing liver and broken up by it into a plexus of small capillary-like vessels termed sinusoids.[XAO]" xsd:string {ontology="XAO", source="XAO:0004147"} property_value: UBPROP:0000003 "Within each vertebrate group, the veins compose a few main functional systems that arise embryologically from what seems to be a common developmental pattern. (...) Early in development, three major sets of paired veins are present: the vitelline veins from the yolk sac, the cardinal veins from the body of the embryo itself, and the lateral abdominal veins from the pelvic region. The paired vitelline veins are among the first vessels to appear in the embryo. They arise over the yolk and follow the yolk stalk into the body. They then turn anteriorly, continue along the gut, and enter the sinus venosus.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000401", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.460", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "check zfa (no text def). Check vitelline/omphalomesenteric distinction in XAO" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0005491 name: glossopharyngeal neural crest namespace: uberon def: "Cranial neural crest which gives rise to the glossopharyngeal ganglion." [ZFA:0007066] subset: vertebrate_core xref: EHDAA2:0000714 xref: EHDAA:660 xref: TAO:0007066 xref: ZFA:0007066 is_a: UBERON:0003099 ! cranial neural crest [Term] id: UBERON:0005496 name: neural tube lateral wall namespace: uberon def: "Portion of tissue on the side of the lumen of the neural tube." [ZFA:0001435] subset: vertebrate_core synonym: "lateral wall neural tube" EXACT [ZFA:0001435] xref: EHDAA2:0001257 xref: EHDAA:2873 xref: EHDAA:912 xref: EMAPA:16166 xref: TAO:0001435 xref: VHOG:0000513 xref: ZFA:0001435 is_a: UBERON:0004121 ! ectoderm-derived structure relationship: part_of UBERON:0001049 ! neural tube [Term] id: UBERON:0005497 name: non-neural ectoderm namespace: uberon comment: Gene notes: One of the first genes to be expressed in nonneural ectoderm in amphioxus is BMP2/4 (Panopoulou et al. 1998). BMP2/4 homologues appear to have a very ancient role in distinguishing neural from nonneural ectoderm; in Drosophila as well as in amphioxus and vertebrates, BMP2/4 homologues are expressed in nonneural ectoderm and function in distinguishing neural from nonneural ectoderm (Francois & Bier, 1995 ; Sasai et al. 1995 ; Wilson & Hemmati-Brivanlou, 1995; Panopoulou et al. 1998). A change in level of BMP2/4 from very high in nonneural ectoderm to low in neural ectoderm appears to be a key factor in development of neural crest (Baker & Bronner-Fraser,1997a,1997b;Erickson&Reedy,1998;Marchantet al.1998 ;Selleck et al. 1998). subset: efo_slim subset: vertebrate_core synonym: "epidermal ectoderm" NARROW [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "epithelial ectoderm" NARROW [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "non neural ectoderm" EXACT [ZFA:0001178] synonym: "surface ectoderm" RELATED [https://github.com/obophenotype/uberon/wiki/The-neural-crest] synonym: "ventral ectoderm" RELATED [ZFA:0001178] xref: EFO:0003643 xref: EHDAA:257 xref: EMAPA:16074 xref: RETIRED_EHDAA2:0001273 xref: TAO:0001178 xref: VHOG:0001372 xref: XAO:0004091 xref: ZFA:0001178 is_a: UBERON:0000479 {source="ZFA"} ! tissue is_a: UBERON:0004121 ! ectoderm-derived structure property_value: editor_note "todo - epidermis? todo - track down EHDAA2 class in new release" xsd:string property_value: RO:0002171 UBERON:0002346 property_value: UBPROP:0000003 "In the early gastrula of vertebrates, factors from the organizer (e.g. noggin, chordin, and follistatin in Xenopus) antagonize the epidermalizing factor bone morphogenetic protein 4 (BMP4), thus dividing the epiblast into neuroectoderm. In Drosophila, decapentaplegic, the homologue of BMP4, interacts similarly with the protein short gastrulation, the homologue of chordin. Thus, a comparable molecular mechanism for distinguishing non-neural ectoderm from neural ectoderm was probably present in the common ancestor of all bilaterally symmetrical animals.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001372", ontology="VHOG", source="DOI:10.1016/S0959-4388(99)00003-3 Holland LZ and Holland ND, Chordate origins of the vertebrate central nervous system. Current Opinion in Neurobiology (1999)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "After gastrulation, neural crest cells are specified at the border of the neural plate and the non-neural ectoderm." xsd:string [Term] id: UBERON:0005498 name: primitive heart tube namespace: uberon def: "Multi-tissue structure that arises from the heart rudiment and will become the heart tube." [ZFA:0000149] subset: vertebrate_core synonym: "early primitive heart tube" NARROW [EMAPA:16208] synonym: "primitive heart tube" EXACT [EMAPA:16215] xref: EHDAA2:0001512 xref: EHDAA:424 xref: EHDAA:436 xref: EMAPA:16215 xref: FMA:321916 xref: SCTID:361522004 xref: TAO:0000149 xref: Wikipedia:Primitive_heart_tube xref: ZFA:0000149 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004120 ! mesoderm-derived structure relationship: develops_from UBERON:0004291 {source="ZFA"} ! heart rudiment relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0005501 name: rhombomere lateral wall namespace: uberon def: "A neural tube lateral wall that is part of a rhombomere." [OBOL:automatic] synonym: "future hindbrain lateral wall" RELATED [EMAPA:35364] xref: EMAPA:32819 xref: EMAPA:35364 is_a: UBERON:0005496 ! neural tube lateral wall intersection_of: UBERON:0005496 ! neural tube lateral wall intersection_of: part_of UBERON:0001892 ! rhombomere relationship: part_of UBERON:0001892 ! rhombomere [Term] id: UBERON:0005563 name: trigeminal neural crest namespace: uberon def: "Cranial neural crest which gives rise to the trigeminal ganglion." [ZFA:0000080] subset: efo_slim subset: vertebrate_core xref: EFO:0003484 xref: EHDAA2:0002083 xref: EHDAA:667 xref: EMAPA:16170 xref: TAO:0000080 xref: VHOG:0000269 xref: ZFA:0000080 is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest is_a: UBERON:0007213 ! mesenchyme derived from head neural crest is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest property_value: editor_note "todo - compare ZFA and EHDAA2 representation" xsd:string property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000269", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005564 name: gonad primordium namespace: uberon def: "Portion of tissue that gives rise to the immature gonad." [ZFA:0001262] subset: efo_slim subset: grouping_class subset: vertebrate_core synonym: "future gonad" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "gonadal primordium" EXACT [ZFA:0001262] synonym: "immature gonad" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "primitive gonad" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "undifferentiated gonad" EXACT [ZFA:0001262] xref: EFO:0003651 xref: EHDAA:5927 xref: EMAPA:17204 xref: RETIRED_EHDAA2:0002148 xref: TAO:0001262 xref: WBbt:0008366 xref: ZFA:0001262 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: has_potential_to_develop_into UBERON:0000991 ! gonad relationship: located_in UBERON:0002323 {gci_relation="part_of", gci_filler="NCBITaxon:33511", notes="conservatively place at deuterostome, excluding acoelomates"} ! coelemic cavity lumen relationship: part_of UBERON:0000990 {source="ZFA"} ! reproductive system property_value: UBPROP:0000001 "Immature reproductive tissue that has not undergone final maturation into either testis or ovary.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001262", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000008 "this is a very broad grouping class" xsd:string [Term] id: UBERON:0005565 name: facio-acoustic neural crest namespace: uberon def: "Cranial neural crest that gives rise to the facio-acoustic ganglion." [ZFA:0000762] subset: vertebrate_core synonym: "facio acoustic neural crest" EXACT [ZFA:0000762] xref: EHDAA2:0000492 xref: EHDAA:658 xref: EMAPA:16312 xref: TAO:0000762 xref: VHOG:0000268 xref: ZFA:0000762 is_a: UBERON:0003099 ! cranial neural crest is_a: UBERON:0007213 ! mesenchyme derived from head neural crest is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: develops_from UBERON:0003849 {source="EHDAA2"} ! mesencephalic neural crest property_value: UBPROP:0000003 "We conclude this section by listing some of the many synapomorphies of craniates, including (1) the neural crest (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000268", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.43", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005594 name: head somite namespace: uberon def: "Somite located in the head region, caudal to the otic vesicle." [PMID:11830559] synonym: "cranial somite" RELATED [XAO:0000313] synonym: "occipital somite" EXACT [PMID:11830559, XAO:0000313] xref: EHDAA2:0003437 xref: EMAPA:16172 xref: XAO:0000313 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0002329 ! somite is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0002329 ! somite intersection_of: develops_from UBERON:0009617 ! head paraxial mesoderm relationship: develops_from UBERON:0009617 {source="EHDAA2"} ! head paraxial mesoderm relationship: part_of UBERON:0009617 {source="EHDAA2"} ! head paraxial mesoderm property_value: UBPROP:0000008 "in humans this includes somites 1-4" xsd:string property_value: UBPROP:0000011 "They provide the epaxial and hypaxial muscles of the neck, the pharyngeal and laryngeal muscles that develop in the caudal branchial arches and the musculature of the tongue. Despite their localisation in the head, myogenic precursors from occipital somites essentially follow the trunk programmes (E. H. Walters and S. D., unpublished). during evolution, have been secondarily incorporated into the head (Gans and Northcutt, 1983)" xsd:string {source="PMID:11830559"} property_value: UBPROP:0000012 "EHDAA2 has both 'head somite' and 'head somite group', with part_of and develops_from for latter" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0005597 name: lung primordium namespace: uberon def: "A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum." [XAO:0001002] subset: efo_slim synonym: "lateral diverticula" RELATED [XAO:0001002] synonym: "lung diverticulum" RELATED [AAO:3010717] synonym: "lung endoderm" RELATED [EFO:0002578] xref: AAO:0011059 xref: EFO:0002578 xref: EMAPA:36007 xref: XAO:0001002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 {source="XAO"} ! primordium relationship: develops_from UBERON:0001041 {source="XAO"} ! foregut relationship: has_potential_to_develop_into UBERON:0000170 ! pair of lungs relationship: part_of UBERON:0008947 ! respiratory primordium [Term] id: UBERON:0005598 name: trunk somite namespace: uberon def: "A somite that is part of a trunk." [OBOL:automatic] xref: AAO:0010385 xref: EHDAA2:0003438 xref: EMAPA:16184 xref: XAO:0000314 is_a: UBERON:0002329 ! somite intersection_of: UBERON:0002329 ! somite intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0005602 name: dorsal mesogastrium namespace: uberon def: "The portion of mesentery attached to the greater curvature of the stomach is named the dorsal mesentery (or dorsal mesogastrium, when referring to the portion at the stomach), and the part which suspends the colon is termed the mesocolon. The dorsal mesogastrium develops into the greater omentum." [Wikipedia:Dorsal_mesentery] synonym: "dorsal mesentery" RELATED [Wikipedia:Dorsal_mesentery] xref: EHDAA2:0000416 xref: EHDAA:3001 xref: EMAPA:17025 xref: MA:0001618 xref: NCIT:C34142 xref: UMLS:C1512038 {source="ncithesaurus:Dorsal_Mesogastrium"} xref: VHOG:0000352 xref: Wikipedia:Dorsal_mesentery is_a: UBERON:0003281 {source="MA"} ! mesentery of stomach relationship: part_of UBERON:0002296 {source="EHDAA2"} ! dorsal mesentery relationship: part_of UBERON:0003281 {source="EHDAA2"} ! mesentery of stomach property_value: UBPROP:0000001 "The dorsal sheet of the primitive mesentery that encloses the stomach. The greater omentum develops from the dorsal mesogastrium. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000352", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesogastrium"} [Term] id: UBERON:0005604 name: extrahepatic part of hepatic duct namespace: uberon synonym: "extrahepatic part of the hepatic duct" EXACT [VHOG:0000215] synonym: "hepatic duct extrahepatic part" EXACT [MA:0001636] xref: EMAPA:16844 xref: MA:0001636 xref: VHOG:0000215 is_a: UBERON:0002394 ! bile duct relationship: part_of UBERON:0003703 {source="MA"} ! extrahepatic bile duct relationship: part_of UBERON:0005171 {source="MA"} ! hepatic duct [Term] id: UBERON:0005609 name: iliac artery namespace: uberon def: "Any of the arteries that arise from a bifurcation of the aorta supplying the pelvic or abdomen. Examples: Common iliac artery, External iliac artery, Internal iliac artery." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Iliac_artery] subset: grouping_class xref: BTO:0004665 xref: EHDAA:2551 xref: EMAPA:17309 xref: galen:IliacArtery xref: MA:0001971 xref: MESH:D007083 xref: NCIT:C12733 xref: RETIRED_EHDAA2:0000807 xref: SCTID:244330006 xref: UMLS:C0020887 {source="ncithesaurus:Iliac_Artery"} xref: Wikipedia:Iliac_artery xref: XAO:0000361 is_a: UBERON:0004573 ! systemic artery relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0010709 ! pelvic complex relationship: supplies UBERON:0002355 ! pelvic region of trunk property_value: IAO:0000232 "this is an extremely loose and flexible grouping class that is the superclass of the mammalian common iliac and its main brahces, together with analagous structures in other tetrapods" xsd:string property_value: UBPROP:0000012 "we place the XAO structure here for now. In terms of analagy, it is more closely related to common iliac, but the relationships currently attached to this class are mammal specific" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0005610 name: iliac vein namespace: uberon def: "Any of the three veins including the common, external and internal iliac veins." [ncithesaurus:Iliac_Vein] synonym: "pelvic vein" RELATED [] xref: EHDAA2:0000811 xref: EMAPA:37151 {source="MA:th"} xref: MA:0002142 xref: MESH:D007084 xref: NCIT:C12734 xref: SCTID:281481002 xref: UMLS:C0020888 {source="ncithesaurus:Iliac_Vein"} is_a: UBERON:0001638 ! vein relationship: drains UBERON:0010708 ! pectoral complex relationship: part_of RO:0002577 ! system [Term] id: UBERON:0005613 name: left dorsal aorta namespace: uberon xref: EHDAA2:0000936 xref: EHDAA:404 xref: EMAPA:16205 xref: MA:0000478 xref: SCTID:361403005 xref: VHOG:0000484 is_a: UBERON:0000947 ! aorta is_a: UBERON:0003513 ! trunk blood vessel relationship: part_of UBERON:0005805 ! dorsal aorta property_value: UBPROP:0000003 "A study of embryos shows that in all vertebrates six arterial arches link the ventral aorta with a pair of lateral dorsal aortae on each side of the body. The latter unite posteriorly to form a single median dorsal aorta wich takes blood to the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000484", ontology="VHOG", source="ISBN:978-0174480198 Roberts MBV, Biology: a functional approach (1986) p.572", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Contributes to the arch of aorta in humans" xsd:string {source="http://emedicine.medscape.com/article/899609-overview"} [Term] id: UBERON:0005614 name: lens anterior epithelium namespace: uberon def: "A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex." [http://orcid.org/0000-0002-6601-2165] synonym: "anterior epithelium of lens vesicle" RELATED [EMAPA:17304] synonym: "anterior surface of lens" RELATED [FMA:58889] synonym: "lens epithelium" BROAD [] synonym: "lens subcapsular epithelium" EXACT [http://www.lab.anhb.uwa.edu.au/mb140/corepages/eye/eye.htm] synonym: "subcapsular lens epithelium" EXACT [FMA:70612] xref: EHDAA2:0000984 xref: EHDAA:9059 xref: EMAPA:17304 xref: EMAPA:17839 xref: FMA:70612 xref: MA:0001302 xref: NCIT:C33641 xref: RETIRED_EHDAA2:0000976 xref: SCTID:362521008 xref: UMLS:C1182652 {source="ncithesaurus:Subcapsular_Epithelium_of_the_Lens"} xref: VHOG:0001425 is_a: UBERON:0001803 ! epithelium of lens intersection_of: UBERON:0000483 ! epithelium intersection_of: adjacent_to UBERON:0001804 ! capsule of lens intersection_of: part_of UBERON:0000965 ! lens of camera-type eye relationship: adjacent_to UBERON:0000389 ! lens cortex relationship: adjacent_to UBERON:0001804 ! capsule of lens property_value: UBPROP:0000010 "Cells of the subcapsular epithelium (or anterior lens cells) are mitotically active. In adult individuals they only cover the anterior 'hemisphere' of the lens. As they divide, cells gradually move towards the equator of the lens where they tranform into lens fibres. The apical part of the gradually elongating cell extends between the subcapsular epithelium and adjacent lens fibres towards the anterior pole of the lens. The basal part extends towards the posterior pole. The nucleus remains close to the equatorial plane of the lens - http://www.lab.anhb.uwa.edu.au/mb140/corepages/eye/eye.htm" xsd:string [Term] id: UBERON:0005616 name: mesenteric artery namespace: uberon def: "Arteries which arise from the abdominal aorta and distribute to most of the intestines." [MESH:A07.231.114.565, Wikipedia:Mesenteric_artery] xref: BTO:0000779 xref: EHDAA2:0001123 xref: EHDAA:4343 xref: EMAPA:17312 xref: MA:0002003 xref: MESH:D008638 xref: NCIT:C52975 xref: SCTID:281084003 xref: UMLS:C0025465 {source="ncithesaurus:Mesenteric_Artery"} xref: VHOG:0001117 xref: Wikipedia:Mesenteric_artery xref: XAO:0000370 is_a: UBERON:0012254 ! abdominal aorta artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000160 ! intestine relationship: supplies UBERON:0000160 ! intestine property_value: editor_note "includes posterior and anterior mesenteric arteries, which branch from the dorsal aorta (see Kardong), and superior and inferior mesenteric arteries" xsd:string [Term] id: UBERON:0005617 name: mesenteric vein namespace: uberon def: "A vein that returns blood from the intestines." [MESH:A07.231.908.670.385, Wikipedia:Mesenteric_vein] synonym: "intestinal vein" RELATED [http://orcid.org/0000-0002-6601-2165] xref: BTO:0002781 xref: EHDAA:4442 xref: EMAPA:17348 xref: MA:0002177 xref: MESH:D008642 xref: NCIT:C53055 xref: RETIRED_EHDAA2:0001125 xref: SCTID:304045008 xref: UMLS:C0025473 {source="ncithesaurus:Mesenteric_Vein"} xref: Wikipedia:Mesenteric_vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0000160 ! intestine relationship: drains UBERON:0000160 ! intestine relationship: part_of RO:0002577 ! system property_value: UBPROP:0000008 "In humans the inferior mesenteric vein empties into the splenic vein, the superior mesenteric vein joins the splenic vein to form the portal vein" xsd:string [Term] id: UBERON:0005619 name: secondary palatal shelf namespace: uberon def: "The outgrowths of the embryonic maxillary prominences that come together during prenatal development to form the secondary palate." [http://medical-dictionary.thefreedictionary.com/palatal+shelves, http://www.indiana.edu/~anat550/hnanim/face/face.html] subset: pheno_slim synonym: "lateral palatine process" EXACT [http://medical-dictionary.thefreedictionary.com/palatal+shelf] synonym: "palatal shelf" EXACT [MA:0001581] synonym: "palatal shelves" RELATED PLURAL [] synonym: "palatine shelf" RELATED [VHOG:0000378] synonym: "secondary palatal shelf" EXACT [] xref: EHDAA2:0001364 xref: EHDAA:9283 xref: EMAPA:17362 xref: FMA:295948 xref: MA:0001581 xref: VHOG:0000378 is_a: UBERON:0010000 ! multicellular anatomical structure is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from UBERON:0005868 {source="cjm"} ! maxillary prominence relationship: part_of UBERON:0003277 {source="EHDAA2"} ! skeleton of upper jaw property_value: editor_note "consider splitting into embryonic/fully formed" xsd:string property_value: UBPROP:0000001 "The outgrowths of the embryonic maxillae that come together during prenatal development to form the secondary palate. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000378", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/palatal"} [Term] id: UBERON:0005622 name: right dorsal aorta namespace: uberon xref: EHDAA2:0001720 xref: EHDAA:406 xref: EMAPA:16206 xref: MA:0000479 xref: SCTID:361404004 xref: VHOG:0000485 is_a: UBERON:0000947 ! aorta is_a: UBERON:0003513 ! trunk blood vessel relationship: part_of UBERON:0005805 ! dorsal aorta property_value: UBPROP:0000003 "A study of embryos shows that in all vertebrates six arterial arches link the ventral aorta with a pair of lateral dorsal aortae on each side of the body. The latter unite posteriorly to form a single median dorsal aorta wich takes blood to the body.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000485", ontology="VHOG", source="ISBN:978-0174480198 Roberts MBV, Biology: a functional approach (1986) p.572", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Normally regresses in humans" xsd:string {source="http://emedicine.medscape.com/article/899609-overview"} [Term] id: UBERON:0005625 name: tubotympanic recess lumen namespace: uberon def: "The cavity formed by the tubotympanic recess epithelium." [https://orcid.org/0000-0002-6601-2165] synonym: "cavity of tubotympanic recess" EXACT [] synonym: "tubotympanic recess" RELATED [EHDAA2:0002095] synonym: "tubotympanic recess cavity" EXACT [] synonym: "tubotympanic recess space" EXACT [] xref: EHDAA2:0002095 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity is_a: UBERON:0007473 ! lumen of epithelial sac intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0010020 ! tubotympanic recess epithelium relationship: develops_from UBERON:0007122 {source="ISBN:0073040584"} ! pharyngeal pouch 1 relationship: luminal_space_of UBERON:0010020 ! tubotympanic recess epithelium relationship: part_of UBERON:0010020 ! tubotympanic recess epithelium [Term] id: UBERON:0005626 name: ventral mesogastrium namespace: uberon def: "Portion of ventral mesentery closest to the stomach." [Wikipedia:Ventral_mesentery] comment: "The primitive gut is enveloped by a mesentery that has a dorsal and a ventral aspect. The ventral mesentery degenerates during development with the exception of the foregut ventral mesentery, which develops into specialized structures (see foregut embryology)." [http://sprojects.mmi.mcgill.ca/embryology/gi/pgm.htm]. todo - check subset: vertebrate_core synonym: "foregut ventral mesentery" RELATED [Wikipedia:Ventral_mesentery] xref: EHDAA2:0002176 xref: EHDAA:3005 xref: EMAPA:17026 xref: MA:0001621 xref: NCIT:C34327 xref: TAO:0005133 xref: UMLS:C1519967 {source="ncithesaurus:Ventral_Mesogastrium"} xref: VHOG:0000351 xref: ZFA:0005133 is_a: UBERON:0003281 ! mesentery of stomach relationship: part_of UBERON:0009668 {source="EHDAA2"} ! ventral mesentery property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/c/cf/Gray984.png" xsd:anyURI property_value: UBPROP:0000001 "The mesentery that originates from the ventral side of the peritoneal cavity.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005133", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The ventral sheet of the primitive mesentery that encloses the stomach. The lesser omentum develops from the ventral mesogastrium. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000351", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/mesogastrium"} [Term] id: UBERON:0005629 name: vascular plexus namespace: uberon def: "A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part." [http://www.medilexicon.com/medicaldictionary.php?t=70052] synonym: "plexus vasculosus" EXACT LATIN [] xref: AEO:0000219 xref: EHDAA2:0004112 xref: EMAPA:35904 xref: FMA:5900 xref: XAO:0004143 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002049 ! vasculature relationship: has_part UBERON:0001981 ! blood vessel property_value: UBPROP:0000001 "In a vascular plexus, the contents of the vessels mix. A plexus allows blood to flow via multiple routes. If one branch of the plexus is obstructed, the blood may flow via the open branches[Wikipedia:Plexus#Circulatory_system]." xsd:string {source="Wikipedia:Plexus#Circulatory_system"} [Term] id: UBERON:0005631 name: extraembryonic membrane namespace: uberon def: "Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo." [ISBN:0073040584] xref: EHDAA2:0004714 xref: FMA:305915 xref: MESH:D005321 xref: SCTID:362840007 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000158 ! membranous layer relationship: part_of UBERON:0016887 ! entire extraembryonic component property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-extraembryonic-membranes" xsd:anyURI property_value: UBPROP:0000008 "stuctures homologous to the four extraembryonic membranes appear in mammals [ISBN:0073040584 (Vertebrates, Kardong)]" xsd:string property_value: UBPROP:0000012 "EHDAA2 is a mereological sum." xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0005637 name: pyloric region epithelium namespace: uberon def: "An epithelium that is part of a pylorus." [OBOL:automatic] xref: EHDAA2:0001582 xref: EMAPA:17633 xref: RETIRED_EHDAA2:0001927 is_a: UBERON:0001276 ! epithelium of stomach intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001166 ! pylorus relationship: part_of UBERON:0001166 ! pylorus [Term] id: UBERON:0005638 name: anterior chamber epithelium namespace: uberon def: "An epithelium that is part of a anterior chamber of eyeball." [OBOL:automatic] xref: EHDAA2:0000130 is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001766 ! anterior chamber of eyeball relationship: part_of UBERON:0001766 ! anterior chamber of eyeball [Term] id: UBERON:0005645 name: manual digit 2 epithelium namespace: uberon def: "An epithelium that is part of a manual digit 2." [OBOL:automatic] synonym: "fore limb digit 2 epithelium" EXACT [OBOL:accepted] synonym: "hand digit 2 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit II epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000518 xref: EMAPA:17433 is_a: UBERON:0005227 ! manual digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: part_of UBERON:0003622 ! manual digit 2 [Term] id: UBERON:0005646 name: manual digit 3 epithelium namespace: uberon def: "An epithelium that is part of a manual digit 3." [OBOL:automatic] synonym: "fore limb digit 3 epithelium" EXACT [OBOL:accepted] synonym: "hand digit 3 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit III epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000524 xref: EMAPA:17436 is_a: UBERON:0005227 ! manual digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: part_of UBERON:0003623 ! manual digit 3 [Term] id: UBERON:0005647 name: manual digit 4 epithelium namespace: uberon def: "An epithelium that is part of a manual digit 4." [OBOL:automatic] synonym: "fore limb digit 4 epithelium" EXACT [OBOL:accepted] synonym: "hand digit 4 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit IV epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000530 xref: EMAPA:17439 is_a: UBERON:0005227 ! manual digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: part_of UBERON:0003624 ! manual digit 4 [Term] id: UBERON:0005648 name: manual digit 5 epithelium namespace: uberon def: "An epithelium that is part of a manual digit 5." [OBOL:automatic] synonym: "fore limb digit 5 epithelium" EXACT [OBOL:accepted] synonym: "hand digit 5 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit V epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000536 xref: EMAPA:17442 is_a: UBERON:0005227 ! manual digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: part_of UBERON:0003625 ! manual digit 5 [Term] id: UBERON:0005649 name: pedal digit 2 epithelium namespace: uberon def: "An epithelium that is part of a pedal digit 2." [OBOL:automatic] synonym: "foot digit 2 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 epithelium" EXACT [OBOL:accepted] synonym: "pedal digit II epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002043 xref: EMAPA:17464 is_a: UBERON:0005226 ! pedal digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: part_of UBERON:0003632 ! pedal digit 2 [Term] id: UBERON:0005650 name: pedal digit 3 epithelium namespace: uberon def: "An epithelium that is part of a pedal digit 3." [OBOL:automatic] synonym: "foot digit 3 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 epithelium" EXACT [OBOL:accepted] synonym: "pedal digit III epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002048 xref: EMAPA:17467 is_a: UBERON:0005226 ! pedal digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: part_of UBERON:0003633 ! pedal digit 3 [Term] id: UBERON:0005651 name: pedal digit 4 epithelium namespace: uberon def: "An epithelium that is part of a pedal digit 4." [OBOL:automatic] synonym: "foot digit 4 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 epithelium" EXACT [OBOL:accepted] synonym: "pedal digit IV epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002053 xref: EMAPA:17470 is_a: UBERON:0005226 ! pedal digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: part_of UBERON:0003634 ! pedal digit 4 [Term] id: UBERON:0005652 name: pedal digit 5 epithelium namespace: uberon def: "An epithelium that is part of a pedal digit 5." [OBOL:automatic] synonym: "foot digit 5 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 epithelium" EXACT [OBOL:accepted] synonym: "pedal digit V epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002058 xref: EMAPA:17473 is_a: UBERON:0005226 ! pedal digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: part_of UBERON:0003635 ! pedal digit 5 [Term] id: UBERON:0005653 name: upper jaw molar epithelium namespace: uberon def: "A dental epithelium that is part of a upper jaw molar." [OBOL:automatic] xref: EHDAA2:0002126 xref: EMAPA:17943 is_a: UBERON:0003235 ! epithelium of upper jaw is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0015839 ! molar epithelium intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003666 ! upper jaw molar relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm relationship: part_of UBERON:0003666 ! upper jaw molar [Term] id: UBERON:0005654 name: lower jaw molar epithelium namespace: uberon def: "A dental epithelium that is part of a lower jaw molar." [OBOL:automatic] xref: EHDAA2:0001026 xref: EMAPA:17922 is_a: UBERON:0003236 ! epithelium of lower jaw is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0015839 ! molar epithelium intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003667 ! lower jaw molar relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm relationship: part_of UBERON:0003667 ! lower jaw molar [Term] id: UBERON:0005656 name: lens vesicle epithelium namespace: uberon def: "An epithelium that is part of a lens vesicle." [OBOL:automatic] xref: EHDAA2:0000987 xref: EMAPA:17165 xref: VHOG:0000532 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005426 ! lens vesicle relationship: part_of UBERON:0005426 ! lens vesicle [Term] id: UBERON:0005658 name: secondary palatal shelf epithelium namespace: uberon def: "An epithelium that is part of a secondary palatal shelf." [OBOL:automatic] synonym: "palatal shelf epithelium" RELATED [VHOG:0001040] xref: EHDAA2:0001365 xref: EMAPA:17363 xref: FMA:312465 xref: VHOG:0001040 is_a: UBERON:0003235 ! epithelium of upper jaw is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0005619 ! secondary palatal shelf relationship: part_of UBERON:0005619 ! secondary palatal shelf [Term] id: UBERON:0005660 name: 2nd arch ectoderm namespace: uberon def: "An ectoderm that is part of a pharyngeal arch 2." [OBOL:automatic] synonym: "2nd pharyngeal arch ectoderm" EXACT [VHOG:0001062] xref: EHDAA2:0000055 xref: EMAPA:16277 xref: EMAPA:16397 xref: EMAPA:16398 xref: RETIRED_EHDAA2:0000064 xref: VHOG:0001062 is_a: UBERON:0000924 ! ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 relationship: part_of UBERON:0003066 ! pharyngeal arch 2 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001062", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005661 name: 3rd arch ectoderm namespace: uberon def: "An ectoderm that is part of a pharyngeal arch 3." [OBOL:automatic] synonym: "3rd pharyngeal arch ectoderm" EXACT [VHOG:0000946] xref: EHDAA2:0000072 xref: EMAPA:16400 xref: EMAPA:16582 xref: EMAPA:16584 xref: RETIRED_EHDAA2:0000079 xref: VHOG:0000946 is_a: UBERON:0000924 ! ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 relationship: part_of UBERON:0003114 ! pharyngeal arch 3 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000946", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005662 name: 4th arch ectoderm namespace: uberon def: "An ectoderm that is part of a pharyngeal arch 4." [OBOL:automatic] synonym: "4th pharyngeal arch ectoderm" EXACT [VHOG:0001095] xref: EHDAA2:0004032 xref: EMAPA:16762 xref: EMAPA:16764 xref: EMAPA:16768 xref: RETIRED_EHDAA2:0000094 xref: VHOG:0001095 is_a: UBERON:0000924 ! ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 relationship: part_of UBERON:0003115 ! pharyngeal arch 4 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001095", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005664 name: 2nd arch endoderm namespace: uberon def: "An endoderm that is part of a pharyngeal arch 2." [OBOL:automatic] synonym: "2nd pharyngeal arch endoderm" EXACT [VHOG:0001108] xref: EHDAA2:0000061 xref: EMAPA:16274 xref: EMAPA:16276 xref: EMAPA:16278 xref: RETIRED_EHDAA2:0000065 xref: VHOG:0001108 is_a: UBERON:0000925 ! endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 relationship: part_of UBERON:0003066 ! pharyngeal arch 2 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001108", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005665 name: 3rd arch endoderm namespace: uberon def: "An endoderm that is part of a pharyngeal arch 3." [OBOL:automatic] synonym: "3rd pharyngeal arch endoderm" EXACT [VHOG:0001081] xref: EHDAA2:0000075 xref: EMAPA:16401 xref: EMAPA:16585 xref: EMAPA:16587 xref: RETIRED_EHDAA2:0000080 xref: VHOG:0001081 is_a: UBERON:0000925 ! endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 relationship: part_of UBERON:0003114 ! pharyngeal arch 3 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001081", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005666 name: 4th arch endoderm namespace: uberon def: "An endoderm that is part of a pharyngeal arch 4." [OBOL:automatic] synonym: "4th pharyngeal arch endoderm" EXACT [VHOG:0001092] xref: EHDAA2:0004033 xref: EMAPA:16765 xref: EMAPA:16767 xref: EMAPA:16769 xref: RETIRED_EHDAA2:0000095 xref: VHOG:0001092 is_a: UBERON:0000925 ! endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 relationship: part_of UBERON:0003115 ! pharyngeal arch 4 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001092", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005667 name: connecting stalk mesoderm namespace: uberon xref: EHDAA2:0000314 is_a: UBERON:0003422 ! mesenchyme of umbilical cord is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0005728 {source="EHDAA2"} ! extraembryonic mesoderm [Term] id: UBERON:0005669 name: peritoneal cavity mesothelium namespace: uberon def: "A mesothelium that is part of a peritoneal cavity." [OBOL:automatic] synonym: "mesothelium of peritoneal component" EXACT [EMAPA:16139] synonym: "mesothelium of peritoneum" EXACT [FMA:18147] synonym: "peritoneal mesothelium" EXACT [BTO:0003156, EMAPA:16139] synonym: "peritoneum" BROAD INCONSISTENT [EMAPA:16139] synonym: "peritoneum mesothelium" EXACT [FMA:18147] xref: BTO:0003156 xref: EHDAA2:0001447 xref: EMAPA:16139 xref: FMA:18147 xref: SCTID:34073007 is_a: UBERON:0001136 ! mesothelium intersection_of: UBERON:0001136 ! mesothelium intersection_of: located_in UBERON:0001179 ! peritoneal cavity relationship: located_in UBERON:0001179 ! peritoneal cavity property_value: UBPROP:0000012 "we believe that this corresponds to EMAPA:16139 based on synonyms and parenthood" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0005672 name: right lung endothelium namespace: uberon def: "An endothelium that is part of a right lung." [OBOL:automatic] xref: EHDAA2:0001755 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0001986 ! endothelium is_a: UBERON:0003364 ! epithelium of right lung intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0005673 name: left lung endothelium namespace: uberon def: "An endothelium that is part of a left lung." [OBOL:automatic] xref: EHDAA2:0000961 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0001986 ! endothelium is_a: UBERON:0003365 ! epithelium of left lung intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0002168 ! left lung [Term] id: UBERON:0005685 name: midgut dorsal mesentery namespace: uberon def: "A dorsal mesentery that is part of a midgut." [OBOL:automatic] xref: EMAPA:16722 xref: EMAPA:17040 xref: EMAPA:18671 xref: RETIRED_EHDAA2:0001187 xref: SCTID:361434009 is_a: UBERON:0002296 ! dorsal mesentery intersection_of: UBERON:0002296 ! dorsal mesentery intersection_of: part_of UBERON:0001045 ! midgut relationship: part_of UBERON:0001045 ! midgut [Term] id: UBERON:0005688 name: lens vesicle cavity namespace: uberon def: "An anatomical cavity that is part of a lens vesicle." [OBOL:automatic] synonym: "cavity of lens" BROAD [] synonym: "cavity of lens vesicle" EXACT [EMAPA:17164] synonym: "lens cavity" BROAD [EHDAA2:0000986] xref: EHDAA2:0000986 xref: EMAPA:17164 xref: VHOG:0000531 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0005426 ! lens vesicle relationship: luminal_space_of UBERON:0005426 ! lens vesicle relationship: part_of UBERON:0005426 ! lens vesicle property_value: UBPROP:0000003 "(...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles. As each optic vesicle grows towards the body surface, its proximal part narrows as the optic stalk, and its distal part invaginates to form a two-layered optic cup. (...) The optic cup induces the overlying surface ectoderm first to thicken as a lens placode and then to invaginate and form a lens vesicle that differentiates into the lens.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000531", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.429", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005689 name: 2nd arch mesenchyme namespace: uberon def: "Mesenchyme that is part of a pharyngeal arch 2." [OBOL:automatic] synonym: "2nd branchial arch mesenchyme" RELATED [] synonym: "2nd pharyngeal arch mesenchyme" EXACT [VHOG:0001102] synonym: "pharyngeal arch 2 mesenchyme" RELATED [] xref: EHDAA2:0000066 xref: EHDAA:625 xref: EMAPA:16279 xref: FMA:295698 xref: VHOG:0001102 is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003066 ! pharyngeal arch 2 relationship: part_of UBERON:0003066 ! pharyngeal arch 2 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001102", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005690 name: 3rd arch mesenchyme namespace: uberon def: "Mesenchyme that is part of a pharyngeal arch 3." [OBOL:automatic] synonym: "3rd branchial arch mesenchyme" RELATED [] synonym: "3rd pharyngeal arch mesenchyme" EXACT [VHOG:0001083] synonym: "pharyngeal arch 3 mesenchyme" RELATED [] xref: EHDAA2:0000081 xref: EHDAA:1094 xref: EMAPA:16402 xref: FMA:295700 xref: VHOG:0001083 is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003114 ! pharyngeal arch 3 relationship: part_of UBERON:0003114 ! pharyngeal arch 3 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001083", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005691 name: 4th arch mesenchyme namespace: uberon def: "Mesenchyme that is part of a pharyngeal arch 4." [OBOL:automatic] synonym: "4th branchial arch mesenchyme" RELATED [] synonym: "4th pharyngeal arch mesenchyme" EXACT [VHOG:0001052] synonym: "pharyngeal arch 4 mesenchyme" RELATED [] xref: EHDAA2:0000096 xref: EHDAA:1677 xref: EMAPA:16770 xref: FMA:295702 xref: VHOG:0001052 is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003115 ! pharyngeal arch 4 relationship: part_of UBERON:0003115 ! pharyngeal arch 4 property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001052", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005692 name: manual digit 2 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing manual digit 2." [OBOL:automatic] synonym: "fore limb digit 2 mesenchyme" EXACT [OBOL:accepted] synonym: "hand digit 2 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit II mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000519 xref: EMAPA:17434 is_a: UBERON:0005257 ! manual digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: part_of UBERON:0003622 ! manual digit 2 [Term] id: UBERON:0005693 name: manual digit 3 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing manual digit 3." [OBOL:automatic] synonym: "fore limb digit 3 mesenchyme" EXACT [OBOL:accepted] synonym: "hand digit 3 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit III mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000525 xref: EMAPA:17437 is_a: UBERON:0005257 ! manual digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: part_of UBERON:0003623 ! manual digit 3 [Term] id: UBERON:0005694 name: manual digit 4 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing manual digit 4." [OBOL:automatic] synonym: "fore limb digit 4 mesenchyme" EXACT [OBOL:accepted] synonym: "hand digit 4 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit IV mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000531 xref: EMAPA:17440 is_a: UBERON:0005257 ! manual digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: part_of UBERON:0003624 ! manual digit 4 [Term] id: UBERON:0005695 name: manual digit 5 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing manual digit 5." [OBOL:automatic] synonym: "fore limb digit 5 mesenchyme" EXACT [OBOL:accepted] synonym: "hand digit 5 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit V mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000537 xref: EMAPA:17443 is_a: UBERON:0005257 ! manual digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: part_of UBERON:0003625 ! manual digit 5 [Term] id: UBERON:0005696 name: pedal digit 2 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing pedal digit 2." [OBOL:automatic] synonym: "foot digit 2 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 mesenchyme" EXACT [OBOL:accepted] synonym: "pedal digit II mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002044 xref: EMAPA:17465 is_a: UBERON:0005255 ! pedal digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: part_of UBERON:0003632 ! pedal digit 2 [Term] id: UBERON:0005697 name: pedal digit 3 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing pedal digit 3." [OBOL:automatic] synonym: "foot digit 3 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 mesenchyme" EXACT [OBOL:accepted] synonym: "pedal digit III mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002049 xref: EMAPA:17468 is_a: UBERON:0005255 ! pedal digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: part_of UBERON:0003633 ! pedal digit 3 [Term] id: UBERON:0005698 name: pedal digit 4 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing pedal digit 4." [OBOL:automatic] synonym: "foot digit 4 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 mesenchyme" EXACT [OBOL:accepted] synonym: "pedal digit IV mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002054 xref: EMAPA:17471 is_a: UBERON:0005255 ! pedal digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: part_of UBERON:0003634 ! pedal digit 4 [Term] id: UBERON:0005699 name: pedal digit 5 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing pedal digit 5." [OBOL:automatic] synonym: "foot digit 5 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 mesenchyme" EXACT [OBOL:accepted] synonym: "pedal digit V mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002059 xref: EMAPA:17474 is_a: UBERON:0005255 ! pedal digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: part_of UBERON:0003635 ! pedal digit 5 [Term] id: UBERON:0005700 name: upper jaw molar odontogenic papilla namespace: uberon def: "An odontogenic papilla that is part of a upper jaw molar." [OBOL:automatic] synonym: "upper jaw molar dental papilla" EXACT [EHDAA2:0002127] synonym: "upper molar mesenchyme" EXACT [] xref: EHDAA2:0002127 xref: EHDAA:8051 xref: EMAPA:17944 is_a: UBERON:0003323 ! mesenchyme of upper jaw is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest is_a: UBERON:0015844 ! molar dental papilla intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003666 ! upper jaw molar relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest relationship: part_of UBERON:0003666 ! upper jaw molar [Term] id: UBERON:0005701 name: lower jaw molar odontogenic papilla namespace: uberon def: "An odontogenic papilla that is part of a lower jaw molar." [OBOL:automatic] synonym: "lower jaw molar dental papilla" EXACT [EHDAA2:0001027] synonym: "lower molar mesenchyme" EXACT [] xref: EHDAA2:0001027 xref: EHDAA:8015 xref: EMAPA:17923 is_a: UBERON:0003324 ! mesenchyme of lower jaw is_a: UBERON:0009891 ! facial mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest is_a: UBERON:0015844 ! molar dental papilla intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003667 ! lower jaw molar relationship: develops_from UBERON:0010336 {source="EHDAA2"} ! mandibular process mesenchyme from neural crest relationship: part_of UBERON:0003667 ! lower jaw molar [Term] id: UBERON:0005702 name: optic eminence mesenchyme namespace: uberon def: "Mesenchyme that is part of a optic eminence." [OBOL:automatic] xref: EHDAA:942 xref: EMAPA:16324 xref: RETIRED_EHDAA2:0001310 xref: VHOG:0001073 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004348 ! optic eminence relationship: part_of UBERON:0004348 ! optic eminence [Term] id: UBERON:0005704 name: secondary palatal shelf mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing secondary palatal shelf." [OBOL:automatic] synonym: "palatal shelf mesenchyme" RELATED [VHOG:0001063] xref: EHDAA2:0001366 xref: EHDAA:9287 xref: EMAPA:17364 xref: VHOG:0001063 is_a: UBERON:0003323 ! mesenchyme of upper jaw is_a: UBERON:0014387 ! mesenchyme derived from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005619 ! secondary palatal shelf relationship: part_of UBERON:0005619 ! secondary palatal shelf [Term] id: UBERON:0005707 name: upper jaw incisor odontogenic papilla namespace: uberon def: "An odontogenic papilla that is part of a upper jaw incisor." [OBOL:automatic] synonym: "upper incisor mesenchyme" EXACT [] synonym: "upper jaw incisor dental papilla" EXACT [EHDAA2:0002123] xref: EHDAA2:0002123 xref: EMAPA:17941 is_a: UBERON:0003317 ! odontogenic papilla of incisor is_a: UBERON:0003323 ! mesenchyme of upper jaw is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003450 ! upper jaw incisor relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest relationship: part_of UBERON:0003450 ! upper jaw incisor [Term] id: UBERON:0005708 name: lower jaw incisor odontogenic papilla namespace: uberon def: "An odontogenic papilla that is part of a lower jaw incisor." [OBOL:automatic] synonym: "lower incisor mesenchyme" EXACT [] synonym: "lower jaw incisor dental papilla" EXACT [EHDAA2:0001023] xref: EHDAA2:0001023 xref: EMAPA:17920 is_a: UBERON:0003317 ! odontogenic papilla of incisor is_a: UBERON:0003324 ! mesenchyme of lower jaw is_a: UBERON:0009891 ! facial mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003451 ! lower jaw incisor relationship: develops_from UBERON:0010336 {source="EHDAA2"} ! mandibular process mesenchyme from neural crest relationship: part_of UBERON:0003451 ! lower jaw incisor [Term] id: UBERON:0005709 name: upper jaw incisor epithelium namespace: uberon def: "A dental epithelium that is part of a upper jaw incisor." [OBOL:automatic] xref: EHDAA2:0002122 xref: EMAPA:17940 is_a: UBERON:0003235 ! epithelium of upper jaw is_a: UBERON:0003355 ! epithelium of incisor is_a: UBERON:0003843 ! dental epithelium is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003450 ! upper jaw incisor relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm relationship: part_of UBERON:0003450 ! upper jaw incisor [Term] id: UBERON:0005710 name: lower jaw incisor epithelium namespace: uberon def: "A dental epithelium that is part of a lower jaw incisor." [OBOL:automatic] xref: EHDAA2:0001022 xref: EMAPA:17919 is_a: UBERON:0003236 ! epithelium of lower jaw is_a: UBERON:0003355 ! epithelium of incisor is_a: UBERON:0003843 ! dental epithelium is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0003843 ! dental epithelium intersection_of: part_of UBERON:0003451 ! lower jaw incisor relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm relationship: part_of UBERON:0003451 ! lower jaw incisor [Term] id: UBERON:0005711 name: foregut duodenum mesentery namespace: uberon def: "A mesentery of duodenum that is part of a foregut." [OBOL:automatic] xref: EHDAA2:0000564 is_a: UBERON:0003397 ! mesentery of duodenum is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0003397 ! mesentery of duodenum intersection_of: part_of UBERON:0001041 ! foregut relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm relationship: part_of UBERON:0001041 ! foregut [Term] id: UBERON:0005712 name: midgut duodenum mesentery namespace: uberon def: "A mesentery of duodenum that is part of a midgut." [OBOL:automatic] xref: EHDAA2:0001193 is_a: UBERON:0003284 ! mesentery of midgut is_a: UBERON:0003397 ! mesentery of duodenum is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0003397 ! mesentery of duodenum intersection_of: part_of UBERON:0001045 ! midgut relationship: develops_from UBERON:0011642 ! oral epithelium from ectoderm [Term] id: UBERON:0005719 name: footplate apical ectodermal ridge namespace: uberon def: "An apical ectodermal ridge that is part of a footplate." [OBOL:automatic] xref: EHDAA2:0000547 xref: EMAPA:17251 is_a: UBERON:0004356 ! apical ectodermal ridge intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0006871 ! embryonic footplate relationship: part_of UBERON:0003373 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! ectoderm of footplate [Term] id: UBERON:0005720 name: hindbrain venous system namespace: uberon def: "A venous system that is part of a hindbrain." [OBOL:automatic] synonym: "rhombencephalon venous system" RELATED [VHOG:0001322] xref: EHDAA2:0000776 xref: EMAPA:18632 xref: VHOG:0001322 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004582 ! venous system intersection_of: UBERON:0004582 ! venous system intersection_of: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0005721 name: pronephric mesoderm namespace: uberon def: "A mesoderm that has the potential to develop into a pronephros." [OBOL:automatic] comment: the intermediate mesoderm of the chick embryo acquires its ability to form kidneys through its interactions with the paraxial mesoderm [ISBN:9780878932504 "Developmental Biology", PMID:10720431 "Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm"]. These interactions induce the expression of TFs including Lim1, Pax2 and Pax6 that cause the intermediate mesoderm to form the kidney subset: efo_slim synonym: "pronephric anlage" RELATED [XAO:0000264] synonym: "pronephric bulge" RELATED [XAO:0000264] synonym: "pronephric mesenchyme" RELATED [XAO:0000264] synonym: "pronephric primordium" RELATED [XAO:0000264] xref: AAO:0011090 xref: EFO:0003479 xref: TAO:0000067 xref: VHOG:0001239 xref: XAO:0000264 xref: ZFA:0000067 is_a: UBERON:0000926 ! mesoderm is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0000926 ! mesoderm intersection_of: has_potential_to_develop_into UBERON:0002120 ! pronephros relationship: develops_from UBERON:0007297 ! presumptive pronephric mesoderm relationship: has_potential_to_develop_into UBERON:0002120 ! pronephros relationship: immediate_transformation_of UBERON:0007297 {source="Bgee:AN"} ! presumptive pronephric mesoderm relationship: part_of UBERON:0003064 {source="ZFA"} ! intermediate mesoderm property_value: UBPROP:0000001 "Portion of tissue that consists of the mesenchymal precursor to the pronephric kidney and that begins to separate from the intermediate mesoderm at NF stage 21 and epithelializes by NF stage 30.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011090", ontology="AAO", source="XAO:curator"} [Term] id: UBERON:0005725 name: olfactory system namespace: uberon def: "A sensory system that is capable of olfaction (the sensory perception of smell)." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim subset: pheno_slim subset: vertebrate_core xref: AAO:0000334 xref: AAO:0000978 xref: BILA:0000144 xref: EFO:0001973 xref: EMAPA:36004 xref: FMA:7190 xref: MA:0002445 xref: NCIT:C94501 xref: NLXANAT:090806 xref: SCTID:362290002 xref: TAO:0001149 xref: UMLS:C0228065 {source="ncithesaurus:Olfactory_System"} xref: Wikipedia:Olfactory_system xref: XAO:0003196 xref: ZFA:0001149 is_a: UBERON:0005726 ! chemosensory system intersection_of: UBERON:0001032 ! sensory system intersection_of: capable_of GO:0007608 ! sensory perception of smell relationship: capable_of GO:0007608 ! sensory perception of smell relationship: existence_ends_during UBERON:0000066 ! fully formed stage property_value: editor_note "consider splitting into main and accessory. See also: vomeronasal organ" xsd:string property_value: editor_note "we make the relationship to nervous system 'overlaps', as the olfactory system includes e.g. apertures in the cranium that are not part of the nervous system" xsd:string property_value: UBPROP:0000001 "The olfactory system is the sensory system used for olfaction, or the sense of smell. Most mammals and reptiles have two distinct parts to their olfactory system: a main olfactory system and an accessory olfactory system. The main olfactory system detects volatile, airborne substances, while the accessory olfactory system senses fluid-phase stimuli. Behavioral evidence indicates that most often, the stimuli detected by the accessory olfactory system are pheromones. The olfactory system is often spoken of along with the gustatory system as the chemosensory senses because both transduce chemical signals into perception[WP][Wikipedia:Olfactory_system]." xsd:string {source="Wikipedia:Olfactory_system"} property_value: UBPROP:0000001 "The sensory system used for olfaction (the sense of smell).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000978", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000008 "In mammals, the main olfactory system detects odorants that are inhaled through the nose, where they contact the main olfactory epithelium, which contains various olfactory receptors. These olfactory receptors are membrane proteins of bipolar olfactory receptor neurons in the olfactory epithelium. Rather than binding specific ligands like most receptors, olfactory receptors display affinity for a range of odor molecules. Olfactory neurons transduce receptor activation into electrical signals in neurons. The signals travel along the olfactory nerve, which belongs to the peripheral nervous system. This nerve terminates in the olfactory bulb, which belongs to the central nervous system. The complex set of olfactory receptors on different olfactory neurons can distinguish a new odor from the background environmental odors and determine the concentration of the odor[WP]." xsd:string [Term] id: UBERON:0005726 name: chemosensory system namespace: uberon subset: functional_classification xref: BILA:0000139 is_a: UBERON:0001032 ! sensory system intersection_of: UBERON:0001032 ! sensory system intersection_of: capable_of GO:0007606 ! sensory perception of chemical stimulus relationship: capable_of GO:0007606 ! sensory perception of chemical stimulus [Term] id: UBERON:0005728 name: extraembryonic mesoderm namespace: uberon def: "." [http://www.ana.ed.ac.uk/database/humat/notes/extraemb/mesoder.htm] synonym: "extra-embryonic mesoderm" EXACT [] synonym: "extraembryonic mesenchyme" EXACT [] xref: EHDAA2:0000474 xref: EMAPA:31862 xref: EMAPA:31863 xref: FMA:296719 xref: VHOG:0000616 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005292 ! extraembryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0003081 ! lateral plate mesoderm relationship: develops_from UBERON:0008780 {source="EHDAA2"} ! inner cell mass derived epiblast [Term] id: UBERON:0005729 name: pectoral appendage field namespace: uberon def: "A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme." [OBOL:automatic] synonym: "pectoral appendage field of lateral plate mesoderm" EXACT [] synonym: "pectoral fin field" NARROW SENSU [ZFA:0001453] xref: TAO:0001453 xref: ZFA:0001453 is_a: UBERON:0005732 ! paired limb/fin field is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0005732 ! paired limb/fin field intersection_of: has_potential_to_develop_into UBERON:0003413 ! pectoral appendage bud mesenchyme relationship: has_potential_to_develop_into UBERON:0003413 ! pectoral appendage bud mesenchyme property_value: UBPROP:0000001 "Embryonic region that develops into the pectoral fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001453", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005730 name: pelvic appendage field namespace: uberon def: "A limb/fin field that has the potential to develop into a pelvic appendage bud mesenchyme." [OBOL:automatic] synonym: "pelvic appendage field of lateral plate mesoderm" EXACT [] synonym: "pelvic fin field" NARROW SENSU [ZFA:0001454] xref: TAO:0001454 xref: ZFA:0001454 is_a: UBERON:0005732 ! paired limb/fin field is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0005732 ! paired limb/fin field intersection_of: has_potential_to_develop_into UBERON:0003412 ! pelvic appendage bud mesenchyme relationship: has_potential_to_develop_into UBERON:0003412 ! pelvic appendage bud mesenchyme property_value: UBPROP:0000001 "Embryonic region that develops into the pelvic fin bud.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001454", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0005732 name: paired limb/fin field namespace: uberon def: "A ring of cells capable of forming a limb or paired fin[Gilbert,modified]." [ISBN:9780878932504] subset: homology_grouping synonym: "limb/fin field of lateral plate mesoderm" EXACT [] synonym: "paired limb/fin field" EXACT [] is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007688 ! anlage intersection_of: UBERON:0007688 ! anlage intersection_of: has_potential_to_developmentally_contribute_to UBERON:0004357 ! paired limb/fin bud relationship: has_potential_to_developmentally_contribute_to UBERON:0004357 ! paired limb/fin bud relationship: part_of UBERON:0003081 {source="ISBN:9780878932504", source="ZFA-inferred"} ! lateral plate mesoderm property_value: editor_note "we represent the field as being a part of the LPM (consistent with ZFA, Gilbert). As a consequence, the relationship between limb bud (with is ectoderm+mesenchyme) stands in a weaker has_developmental_contribution_from relation to the field - TODO implement this." xsd:string [Term] id: UBERON:0005733 name: limb field namespace: uberon def: "A ring of cells capable of forming a limb." [ISBN:9780878932504] comment: the central portion of the limb field gives rise to the limb proper. mesenchyme cells proliferate from from the somatic layer of limb field lateral plate mesoderm (limb skeletal precursors) and from the somites (limb muscle precursors) . these mesenchymal cells accumulate under the ectedermal tissue to make a limb bud. // The lateral plate mesoderm in the limb field is also special in that it will induce myoblasts to migrate out from the somites and enter the limb bud. No other region of the lateral plate mesoderm will do that (Hayashi and Ozawa 1995) synonym: "limb field of lateral plate mesoderm" EXACT [] is_a: UBERON:0005732 ! paired limb/fin field intersection_of: UBERON:0005732 ! paired limb/fin field intersection_of: has_potential_to_developmentally_contribute_to UBERON:0004347 ! limb bud relationship: has_potential_to_developmentally_contribute_to UBERON:0004347 ! limb bud [Term] id: UBERON:0005734 name: tunica adventitia of blood vessel namespace: uberon def: "The outermost layer of a blood vessel, composed mainly of fibrous tissue." [ISBN:0073040584, Wikipedia:Tunica_externa_(vessels)] synonym: "adventitia externa" EXACT [Wikipedia:Tunica_externa_(vessels)] synonym: "external coat" RELATED [Wikipedia:Tunica_externa_(vessels)] synonym: "tunica adventitia" EXACT [Wikipedia:Tunica_externa_(vessels)] synonym: "tunica adventitia of vessel" EXACT [Wikipedia:Tunica_externa_(vessels)] synonym: "tunica adventitia vasorum" RELATED LATIN [Wikipedia:Tunica_externa_(vessels)] synonym: "tunica externa vasorum" RELATED LATIN [Wikipedia:Tunica_externa_(vessels)] xref: BTO:0002010 xref: EMAPA:36299 xref: NCIT:C33818 xref: SCTID:61066005 xref: UMLS:C0225342 {source="ncithesaurus:Tunica_Adventitia"} xref: Wikipedia:Tunica_externa_(vessels) is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004797 {source="cjm"} ! blood vessel layer is_a: UBERON:0005742 ! adventitia relationship: composed_primarily_of UBERON:0011824 ! fibrous connective tissue relationship: has_quality PATO:0002462 ! collagenous property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/32/Illu_artery.jpg" xsd:anyURI property_value: editor_note "TODO - note terminological problems. WP says tunica external layer of blood vessel. FMA says tunica externa = adventitia, and is FMA adventitia covers other kinds of vessels. Here we opt for a lengthier name that attempts to disambiguate. There is no precise FMA equivalent, as FMA has tunica externa of arteries, veins, genital ducts etc as siblings" xsd:string property_value: UBPROP:0000001 "The outermost layer of a blood vessel, surrounding the tunica media. It is mainly composed of collagen. The collagen serves to anchor the blood vessel to nearby organs, giving it stability[Wikipedia:Tunica_externa_(vessels)]." xsd:string {source="Wikipedia:Tunica_externa_(vessels)"} [Term] id: UBERON:0005740 name: tunica intima of artery namespace: uberon def: "A tunica intima that is part of a artery." [OBOL:automatic] synonym: "arterial intima" EXACT [EV:0100028] synonym: "tunica interna (intima)(arteriae)" EXACT [FMA:14272] xref: EMAPA:36293 xref: EV:0100028 xref: FMA:14272 xref: galen:IntimaOfArtery xref: SCTID:40022005 is_a: UBERON:0002523 ! tunica intima is_a: UBERON:0004797 ! blood vessel layer intersection_of: UBERON:0002523 ! tunica intima intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0000415 ! artery wall [Term] id: UBERON:0005742 name: adventitia namespace: uberon def: "An outermost connective tissue covering of an organ, vessel, or other structure[WP]." [Wikipedia:Adventitia] subset: grouping_class subset: human_reference_atlas synonym: "tunica advetitia" NARROW [Wikipedia:Adventitia] synonym: "tunica externa" NARROW [FMA:45635] xref: BTO:0002010 xref: FMA:45635 xref: MESH:D063194 xref: SCTID:30180000 xref: Wikipedia:Adventitia is_a: UBERON:0004923 ! organ component layer relationship: composed_primarily_of UBERON:0002384 ! connective tissue property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e8/Illu_esophageal_layers.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0005744 name: bone foramen namespace: uberon def: "Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves." [TAO:curator] subset: vertebrate_core synonym: "foramen" BROAD [ZFA:0005386] xref: AAO:0010438 xref: TAO:0001736 xref: VHOG:0001760 xref: ZFA:0005386 is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: part_of UBERON:0001474 ! bone element relationship: part_of UBERON:0001474 ! bone element property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/81/Gray193.png" xsd:anyURI property_value: UBPROP:0000012 "in FMA and ZFA this is a conduit space, not a conduit. Note there may be some additional disambiguation required: foramen is used loosely in the sense of any opening (e.g. foramen primum). FMA appears to use cranial conduit (undefined) in the sense of any foramen of the skull (includes mental foramen, which is not in the cranium proper)." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0005753 name: caudal part of nephrogenic cord namespace: uberon def: "The metanephros develops from the most caudal part of the nephrogenic cord that is itself derived from the intermediate plate mesoderm." [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] synonym: "caudal portion of nephrogenic cord" EXACT [OBOL:automatic] synonym: "caudal region of nephrogenic cord" EXACT [OBOL:automatic] synonym: "rear part of nephrogenic cord" EXACT [OBOL:automatic] synonym: "rear portion of nephrogenic cord" EXACT [Wikipedia:Metanephros#Metanephros] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004875 ! nephrogenic cord [Term] id: UBERON:0005754 name: rostral part of nephrogenic cord namespace: uberon def: "The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros." [http://www.gudmap.org/About/Tutorial/DevMUS.html#DMK_Nephron] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004875 ! nephrogenic cord [Term] id: UBERON:0005764 name: acellular membrane namespace: uberon def: "An acellular anatomical structure that is the bounding layer of a anatomical structure." [OBOL:automatic] subset: common_anatomy xref: FMA:63871 is_a: UBERON:0000476 ! acellular anatomical structure intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: bounding_layer_of UBERON:0000061 ! anatomical structure relationship: bounding_layer_of UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000061 ! anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0005769 name: basement membrane of epithelium namespace: uberon def: "An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Basement_membrane] synonym: "basement membrane" RELATED [FMA:63872] synonym: "basement membrane of connective tissue" EXACT [FMA:63872] synonym: "membrana basalis" EXACT LATIN [Wikipedia:Basement_membrane] xref: AAO:0010596 xref: FMA:63872 xref: GAID:915 xref: NCIT:C13191 xref: SCTID:68989006 xref: UMLS:C0004799 {source="ncithesaurus:Basement_Membrane"} xref: Wikipedia:Basement_membrane is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0005764 {source="FMA"} ! acellular membrane relationship: adjacent_to CL:0000066 ! epithelial cell relationship: composed_primarily_of GO:0005604 ! basement membrane relationship: has_part GO:0005587 ! collagen type IV trimer relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of UBERON:0000483 ! epithelium property_value: IAO:0000232 "this class represents a continuous sheet of basement membrane which can underlie multiple epithelial cells over large regions. In contrast, the GO class 'basal membrane' represents a portion of substance on the scale of a single cell." xsd:string property_value: RO:0002175 NCBITaxon:80999 {source="http://palaeos.com/metazoa/porifera/homoscleromorpha.html"} [Term] id: UBERON:0005792 name: nephric ridge namespace: uberon def: "Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions." [http://cwx.prenhall.com/bookbind/pubbooks/martini10/chapter27/custom2/deluxe-content.html] synonym: "nephric cord" RELATED [VHOG:0001240] xref: EHDAA2:0001242 xref: EHDAA:1015 xref: EMAPA:16368 xref: VHOG:0001240 is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0001008 ! renal system relationship: part_of UBERON:0004122 ! genitourinary system property_value: editor_note "TODO - check ridge vs cord vs nephrogenic cord vs blastema" xsd:string [Term] id: UBERON:0005795 name: embryonic uterus namespace: uberon synonym: "fetal uterus" EXACT [FMA:72173] xref: FMA:72173 xref: SCTID:255782009 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0000995 ! uterus [Term] id: UBERON:0005800 name: section of aorta namespace: uberon def: "Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle." [ncithesaurus:Aortic_Segment] synonym: "aortic section" EXACT [] synonym: "aortic segment" RELATED [FMA:13087] synonym: "portion of aorta" RELATED [] synonym: "segment of aorta" RELATED [FMA:13087] xref: FMA:13087 xref: NCIT:C34027 xref: SCTID:119203005 xref: UMLS:C0506947 {source="ncithesaurus:Aortic_Segment"} is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0013522 ! subdivision of tube relationship: part_of UBERON:0000947 ! aorta [Term] id: UBERON:0005805 name: dorsal aorta namespace: uberon def: "The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." [GO:0035907, https://sourceforge.net/p/geneontology/ontology-requests/8525/] subset: vertebrate_core synonym: "aorta dorsalis" EXACT LATIN [XAO:0000051] synonym: "aortae dorsales" RELATED LATIN [Wikipedia:Dorsal_aorta] synonym: "DA" EXACT [ZFA:0000014] synonym: "dorsal aorta root" RELATED [VHOG:0000264] synonym: "dorsal aortae" RELATED PLURAL [Wikipedia:Dorsal_aorta] synonym: "dorsal aortic root" RELATED [VHOG:0000264] synonym: "dorsal aortæ" RELATED PLURAL [Wikipedia:Dorsal_aorta] xref: AAO:0011029 xref: BTO:0004673 xref: EHDAA:402 xref: EMAPA:18606 xref: SCTID:338637006 xref: TAO:0000014 xref: VHOG:0000264 xref: Wikipedia:Dorsal_aorta xref: XAO:0000051 xref: ZFA:0000014 is_a: UBERON:0000947 ! aorta is_a: UBERON:0003513 ! trunk blood vessel relationship: develops_from UBERON:0001917 ! endothelium of artery relationship: develops_from UBERON:0003064 ! intermediate mesoderm relationship: part_of UBERON:0002201 ! vasculature of trunk property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/fb/Gray459.png" xsd:anyURI property_value: UBPROP:0000001 "Each primitive aorta receives anteriorly a vein 'the vitelline vein' from the yolk-sac, and is prolonged backward on the lateral aspect of the notochord under the name of the dorsal aorta. The dorsal aortae give branches to the yolk-sac, and are continued backward through the body-stalk as the umbilical arteries to the villi of the chorion. The two dorsal aortae combine to become the descending aorta in later development[WP]." xsd:string {source="Wikipedia:Dorsal_aorta"} property_value: UBPROP:0000001 "Principal unpaired, median artery of the trunk, leading from the paired roots (radices) of the dorsal aorta to the caudal artery. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000014", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "The artery in vertebrate embryos that transports blood from the aortic arches to the trunk and limbs. In adult fish it is a major artery that carries oxygenated blood from the efferent branchial arteries to branches that supply the body organ. In adult tetrapods it arises from the systemic arch" xsd:string {source="BTO:0004673"} property_value: UBPROP:0000002 "relationship loss: part_of axial vasculature (TAO:0001073)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000014", ontology="TAO"} property_value: UBPROP:0000003 "When vertebrates first appeared, they must have possessed a ventral and dorsal aorta with aortic arches between them.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000264", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.620", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005806 name: portal system namespace: uberon def: "In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]." [Wikipedia:Portal_venous_system] synonym: "portal venous system" EXACT [FMA:45628] xref: FMA:45628 xref: MESH:D011168 xref: NCIT:C33344 xref: SCTID:362063001 xref: UMLS:C0226727 {source="ncithesaurus:Portal_Venous_System"} xref: Wikipedia:Portal_venous_system is_a: UBERON:0002049 ! vasculature [Term] id: UBERON:0005808 name: bone tissue of long bone namespace: uberon def: "A bone tissue that is part of a long bone." [OBOL:automatic] synonym: "osseous tissue of long bone" RELATED [FMA:83117] xref: FMA:83117 xref: SCTID:425475006 is_a: UBERON:0002481 ! bone tissue intersection_of: UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0002495 ! long bone relationship: part_of UBERON:0002495 ! long bone [Term] id: UBERON:0005813 name: tubercle namespace: uberon def: "A round nodule, small eminence, or warty outgrowth on an anatomical surface, such as bones, skin, or within the lungs (in the case of tuberculosis). They are also found on the leading edge of Humpback Whale's flippers, improving fluid flow over the flipper's surface[WP]." [Wikipedia:Tubercle_(anatomy)] subset: grouping_class subset: upper_level synonym: "tuber" RELATED [] xref: AAO:0010605 xref: BTO:0002173 xref: FMA:75429 xref: Wikipedia:Tubercle_(anatomy) is_a: UBERON:0004529 ! anatomical projection [Term] id: UBERON:0005814 name: arch of atlas namespace: uberon def: "A vertebral arch that is part of the first cervical vertebra." [http://orcid.org/0000-0002-6601-2165] synonym: "atlas arch" EXACT [FMA:23975] xref: FMA:23975 xref: SCTID:272708001 xref: Wikipedia:Arch_of_the_atlas is_a: UBERON:0010358 ! arch of centrum of vertebra intersection_of: UBERON:0010358 ! arch of centrum of vertebra intersection_of: part_of UBERON:0001092 ! vertebral bone 1 relationship: part_of UBERON:0001092 ! vertebral bone 1 [Term] id: UBERON:0005837 name: fasciculus of spinal cord namespace: uberon def: "A fascicle that is part of a spinal cord." [OBOL:automatic] synonym: "spinal cord fasciculus" EXACT [FMA:75799] xref: FMA:75799 is_a: UBERON:0001019 ! nerve fasciculus is_a: UBERON:0011215 ! central nervous system cell part cluster intersection_of: UBERON:0001019 ! nerve fasciculus intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0005838 name: fasciculus of brain namespace: uberon def: "A fascicle that is part of a brain." [OBOL:automatic] synonym: "brain fasciculus" EXACT [FMA:83844] xref: FMA:83844 is_a: UBERON:0001019 ! nerve fasciculus is_a: UBERON:0011215 ! central nervous system cell part cluster intersection_of: UBERON:0001019 ! nerve fasciculus intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0002316 ! white matter [Term] id: UBERON:0005843 name: sacral spinal cord namespace: uberon def: "A spinal cord segment that adjacent_to a sacral region." [OBOL:automatic] subset: human_reference_atlas synonym: "pars sacralis medullae spinalis" EXACT LATIN [FMA:256623, FMA:TA] synonym: "sacral segment of spinal cord" EXACT [FMA:256623] synonym: "sacral segments of spinal cord [1-5]" EXACT [FMA:256623] synonym: "segmenta sacralia medullae spinalis [1-5]" EXACT LATIN [FMA:256623, FMA:TA] xref: BIRNLEX:1275 xref: FMA:256623 xref: MA:0003085 xref: NCIT:C12896 xref: SCTID:244438003 xref: UMLS:C0581669 {source="BIRNLEX:1275", source="ncithesaurus:Sacral_Spinal_Cord"} xref: UMLS:C1280196 {source="BIRNLEX:1275"} is_a: UBERON:0005844 ! spinal cord segment intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: adjacent_to UBERON:0005473 ! sacral region relationship: adjacent_to UBERON:0005473 ! sacral region property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0005844 name: spinal cord segment namespace: uberon synonym: "axial part of spinal cord" EXACT [BIRNLEX:2665] synonym: "axial regional part of spinal cord" EXACT [BIRNLEX:2665] synonym: "segment of spinal cord" EXACT [FMA:62420] synonym: "spinal neuromeres" RELATED PLURAL [TAO:0001332] xref: BIRNLEX:2665 xref: FMA:62420 xref: MA:0003080 xref: SCTID:278748001 is_a: UBERON:0001948 ! regional part of spinal cord property_value: editor_note "This is currently used loosely to refer to cervical, lumbar, etc as well as the metamerically repeated segments, which may correspond more closely with the ZFA neuromere term" xsd:string [Term] id: UBERON:0005845 name: caudal segment of spinal cord namespace: uberon def: "A spinal cord segment that adjacent_to a caudal region." [OBOL:automatic] comment: for spinal cord segments, we treat coccygeal/caudal as synonyms - we only differentiate where bone is concerned synonym: "coccygeal segment of spinal cord" EXACT [FMA:256635] synonym: "coccygeal segments of spinal cord [1-3]" EXACT [FMA:256635] synonym: "pars coccygea medullae spinalis" EXACT LATIN [FMA:256635, FMA:TA] synonym: "segmenta coccygea" RELATED LATIN [NeuroNames:1656] synonym: "segmenta coccygea medullae spinalis [1-3]" EXACT LATIN [FMA:256635, FMA:TA] xref: FMA:256635 xref: MA:0003084 xref: neuronames:1656 xref: SCTID:278753006 is_a: UBERON:0005844 ! spinal cord segment intersection_of: UBERON:0005844 ! spinal cord segment intersection_of: adjacent_to UBERON:0006071 ! caudal region relationship: adjacent_to UBERON:0006071 ! caudal region [Term] id: UBERON:0005856 name: developing mesenchymal condensation namespace: uberon def: "A delimited region of dense mesenchyme within looser mesenchyme." [AEO:0000148] synonym: "mesenchyme condensation" EXACT [EMAPA:25351] xref: AEO:0000148 xref: EHDAA2_RETIRED:0003148 xref: EHDAA:8979 is_a: UBERON:0007524 {source="AEO"} ! dense mesenchyme tissue is_a: UBERON:0011585 {source="cjm"} ! cell condensation relationship: composed_primarily_of CL:0000335 {source="AEO-modified-relation"} ! mesenchyme condensation cell [Term] id: UBERON:0005863 name: cartilaginous condensation namespace: uberon def: "Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes." [GO:curator] synonym: "cartilage condensation" EXACT [EMAPA:25353] synonym: "cartilagenous condensation" EXACT [EHDAA2:0003147] synonym: "chondrogenic condensation" EXACT [VSAO:0000092] xref: AEO:0000147 xref: EHDAA2_RETIRED:0003147 xref: EMAPA:32731 xref: VSAO:0000092 xref: XAO:0004022 is_a: UBERON:0005856 {source="AEO"} ! developing mesenchymal condensation relationship: develops_from UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0004288 {source="AEO"} ! skeleton property_value: UBPROP:0000012 "isa cell condensation in VSAO; has_part chondroblast in AEO" xsd:string {external_ontology="VSAO"} [Term] id: UBERON:0005865 name: pre-muscle condensation namespace: uberon alt_id: UBERON:0008714 synonym: "pre muscle mass" EXACT [] synonym: "premuscle mass" EXACT [] xref: AEO:0000149 xref: EHDAA2_RETIRED:0003149 is_a: UBERON:0005856 ! developing mesenchymal condensation intersection_of: UBERON:0005856 ! developing mesenchymal condensation intersection_of: composed_primarily_of CL:0000680 ! muscle precursor cell relationship: composed_primarily_of CL:0000680 ! muscle precursor cell relationship: has_part CL:0000680 {source="AEO"} ! muscle precursor cell relationship: has_potential_to_develop_into UBERON:0005090 ! muscle structure [Term] id: UBERON:0005866 name: pre-cartilage condensation namespace: uberon def: "A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts." [AEO:0000150, AEO:JB] synonym: "pre-chondrogenic condensation" EXACT [] synonym: "precartilage condensation" EXACT [] synonym: "precartilagenous condensation" EXACT [] synonym: "prechondrogenic condensation" EXACT [] xref: AEO:0000150 xref: EHDAA2:0003150 xref: EMAPA:32736 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0005856 {source="AEO"} ! developing mesenchymal condensation relationship: has_potential_to_develop_into UBERON:0007844 ! cartilage element relationship: part_of UBERON:0004288 {source="AEO"} ! skeleton property_value: UBPROP:0000001 "A closely packed aggregation of mesenchymal cells just prior to their differentiation into embryonic cartilage." xsd:string {source="http://dictionary.reference.com/browse/precartilage"} [Term] id: UBERON:0005867 name: mandibular prominence namespace: uberon def: "The paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip." [ISBN:0-683-40008-8, MP:0010939] subset: pheno_slim synonym: "mandibular process" RELATED [Wikipedia:Mandibular_prominence] synonym: "mandibular swelling" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "prominentia mandibularis" RELATED LATIN [Wikipedia:Mandibular_prominence] xref: EHDAA2:0001061 xref: EHDAA:5871 xref: EMAPA:17355 xref: FMA:293051 xref: NCIT:C34204 xref: UMLS:C1512982 {source="ncithesaurus:Mandibular_Prominence"} xref: Wikipedia:Mandibular_prominence is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0012314 ! embryonic facial prominence relationship: develops_from UBERON:0007237 ! 1st arch mandibular component relationship: part_of UBERON:0000166 ! oral opening property_value: editor_note "check develops_from" xsd:string [Term] id: UBERON:0005868 name: maxillary prominence namespace: uberon def: "The paired dorsal prominences formed by bifurcation of the first pharyngeal arches in the embryo that unite with the ipsilateral medial nasal process to form the upper jaw." [ISBN:0-683-40008-8, MP:0010940] subset: pheno_slim synonym: "embryonic maxillary process" EXACT [] synonym: "maxillary process" EXACT [EHDAA2:0001070] synonym: "maxillary process of embryo" EXACT [] synonym: "prominentia maxilaris" RELATED LATIN [Wikipedia:Maxillary_prominence] xref: EHDAA2:0001070 xref: EHDAA:5877 xref: EMAPA:17359 xref: FMA:293049 xref: NCIT:C34206 xref: SCTID:346355001 xref: UMLS:C1513037 {source="ncithesaurus:Maxillary_Prominence"} xref: Wikipedia:Maxillary_prominence is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0007238 ! 1st arch maxillary component property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray48.png" xsd:anyURI [Term] id: UBERON:0005870 name: olfactory pit namespace: uberon def: "An indentation of the olfactory placode which ends when the pits hollows out to form the nasopharynx[GO]." [GO:0060166, Wikipedia:Nasal_pit] subset: efo_slim subset: pheno_slim synonym: "nasal pit" EXACT [XAO:0000275] xref: AAO:0011068 xref: EFO:0003496 xref: EHDAA2:0001295 xref: EHDAA:4772 xref: EMAPA:16800 xref: FMA:295840 xref: SCTID:361485001 xref: Wikipedia:Nasal_pit xref: XAO:0000275 xref: XAO:0004073 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0016566 {source="EHDAA2"} ! pit relationship: develops_from UBERON:0003050 {source="XAO:0000275 nasal pit"} ! olfactory placode relationship: located_in UBERON:0005384 {source="EHDAA2"} ! nasal cavity epithelium relationship: part_of UBERON:0000004 {source="EMAPA"} ! nose relationship: part_of UBERON:0000922 ! embryo property_value: editor_note "we represent the relationship as develops from, though in fact the pit is formed as an indentation in the placode" xsd:string property_value: UBPROP:0000001 "By the upgrowth of the surrounding parts the olfactory areas are converted into pits, the nasal pits or olfactory pits, which indent the fronto-nasal process and divide it into a medial and two lateral nasal processes[Wikipedia:Nasal_pit]." xsd:string {source="Wikipedia:Nasal_pit"} [Term] id: UBERON:0005872 name: 1st arch pharyngeal cleft namespace: uberon def: "A groove that is situated between the 1st and 2nd pharyngeal arch." [ISBN:0124020607, VHOG:OG] subset: vertebrate_core synonym: "1st arch branchial groove" EXACT [EHDAA2:0000008] synonym: "1st arch groove ectoderm" EXACT [EHDAA2:0000009] synonym: "1st branchial cleft" RELATED [EMAPA:16119] synonym: "1st pharyngeal cleft" RELATED [VHOG:0000969] synonym: "1st pharyngeal groove" EXACT [VHOG:0000969] synonym: "1st pharyngeal groove ectoderm" EXACT [VHOG:0000554] synonym: "branchial groove of 1st arch" EXACT [EMAPA:16119] xref: EHDAA2:0000009 xref: EHDAA:575 xref: EMAPA:16119 xref: VHOG:0000554 xref: VHOG:0000969 is_a: UBERON:0005879 ! pharyngeal cleft intersection_of: UBERON:0005879 ! pharyngeal cleft intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 intersection_of: overlaps UBERON:0004362 ! pharyngeal arch 1 relationship: overlaps UBERON:0003066 ! pharyngeal arch 2 relationship: overlaps UBERON:0004362 ! pharyngeal arch 1 property_value: UBPROP:0000003 "In all jawed vertebrates the first arch forms the jaw, while the second arch forms the hyoid apparatus. These two arches are separated by the first pharyngeal pouch and cleft.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000969", ontology="VHOG", source="DOI:10.1016/j.semcdb.2010.01.022 Grevellec A, Tucker AS, The pharyngeal pouches and clefts: development, evolution, structure and derivatives. Seminars in Cell and Developmental Biology (2010)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0005873 name: 2nd arch pharyngeal cleft namespace: uberon def: "A groove that is situated between the 2nd and 3rd pharyngeal arch." [ISBN:0124020607, VHOG:OG] subset: vertebrate_core synonym: "2nd arch branchial groove" EXACT [EHDAA2:0000054] synonym: "2nd arch groove ectoderm" EXACT [EHDAA2:0000057] synonym: "2nd branchial cleft" RELATED [EMAPA:16396] synonym: "2nd pharyngeal cleft" RELATED [VHOG:0000972] synonym: "2nd pharyngeal groove" EXACT [VHOG:0000972] synonym: "2nd pharyngeal groove ectoderm" EXACT [VHOG:0000568] synonym: "branchial groove of 2nd arch" EXACT [EMAPA:16396] xref: EHDAA2:0000057 xref: EHDAA:613 xref: EMAPA:16396 xref: VHOG:0000568 xref: VHOG:0000972 is_a: UBERON:0005879 ! pharyngeal cleft intersection_of: UBERON:0005879 ! pharyngeal cleft intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 relationship: overlaps UBERON:0003066 ! pharyngeal arch 2 relationship: overlaps UBERON:0003114 ! pharyngeal arch 3 [Term] id: UBERON:0005874 name: 3rd arch pharyngeal cleft namespace: uberon def: "A groove that is situated between the 3rd and 4th pharyngeal arch." [ISBN:0124020607, VHOG:OG] subset: vertebrate_core synonym: "3rd arch branchial groove" EXACT [EHDAA2:0000071] synonym: "3rd arch groove ectoderm" EXACT [EHDAA2:0000074] synonym: "3rd branchial cleft" RELATED [EMAPA:16581] synonym: "3rd pharyngeal cleft" RELATED [VHOG:0000973] synonym: "3rd pharyngeal groove" EXACT [VHOG:0000973] synonym: "3rd pharyngeal groove ectoderm" EXACT [VHOG:0000572] synonym: "branchial groove of 3rd arch" EXACT [EMAPA:16581] xref: EHDAA2:0000074 xref: EHDAA:1082 xref: EMAPA:16581 xref: VHOG:0000572 xref: VHOG:0000973 is_a: UBERON:0005879 ! pharyngeal cleft intersection_of: UBERON:0005879 ! pharyngeal cleft intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 intersection_of: overlaps UBERON:0003115 ! pharyngeal arch 4 relationship: overlaps UBERON:0003114 ! pharyngeal arch 3 relationship: overlaps UBERON:0003115 ! pharyngeal arch 4 [Term] id: UBERON:0005876 name: undifferentiated genital tubercle namespace: uberon def: "The embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin." [https://github.com/obophenotype/uberon/issues/1230, MGI:anna, MP:0011771] subset: pheno_slim synonym: "genital tubercle" RELATED [EMAPA:17382] synonym: "phallic tubercle" RELATED [] synonym: "tuberculum genitale" RELATED LATIN [Wikipedia:Genital_tubercle] synonym: "tuberculum phallicum" RELATED LATIN [Wikipedia:Genital_tubercle] synonym: "undifferentiated genital tubercle" EXACT [VHOG:0000583] xref: EHDAA2:0000705 xref: EHDAA:5925 xref: EMAPA:17382 xref: FMA:302888 xref: SCTID:308798005 xref: VHOG:0000583 xref: Wikipedia:Genital_tubercle is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0004874 ! somatopleure relationship: has_potential_to_develop_into UBERON:0011757 ! differentiated genital tubercle relationship: only_in_taxon NCBITaxon:32524 {source="https://github.com/obophenotype/uberon/issues/1230"} ! Amniota relationship: part_of UBERON:0009196 {source="EHDAA2"} ! indifferent external genitalia property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d6/Gray1119.png" xsd:anyURI property_value: UBPROP:0000001 "embryonic anlage of the external genitalia, which emerges as paired swellings ventral to the cloacal membrane, is proposed to be derived from all three germ layers, and gives rise to the penis, clitoris, scrotum, labia, and foreskin; GT development is indistinguishable in male and female mouse embryos until ~E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP]" xsd:string {ontology="MP"} property_value: UBPROP:0000001 "The eminence in the embryo which develops into the clitoris or penis. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000583", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/genital+tubercle"} property_value: UBPROP:0000003 "In mammalian embryos, male and female external genitalia develop from the genital tubercle.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000583", ontology="VHOG", source="DOI:10.1242/dev.036830 Seifert AW, Yamaguchi T, Cohn MJ, Functional and phylogenetic analysis shows that Fgf8 is a marker of genital induction in mammals but is not required for external genital development. Development (2009)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "All amniotes studied to date initiate external genital development with the formation of paired genital swellings. In mammals, archosaurs, and turtles, these swellings merge to form a single genital tubercle, the precursor of the penis and clitoris[PMID:24960313]" xsd:string property_value: UBPROP:0000008 "GT development is indistinguishable in male and female mouse embryos until approximately E16, when the urethral plate begins to be masculinized to form the penile urethra, marking the beginning of an androgen-dependent phase of sexual differentiation[MP:0011771]" xsd:string property_value: UBPROP:0000008 "todo - add taxon constraints" xsd:string property_value: UBPROP:0000012 "we assume the EMAPA class is the undifferentiated form based on TS timings" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0005879 name: pharyngeal cleft namespace: uberon def: "An external pocketing of pharyngeal ectoderm that contacts a region of endoderm (a pharyngeal pouch) and interdigitates in the anterior and posterior directions by the pharyngeal arches." [http://orcid.org/0000-0002-6601-2165, PMID:23020903] subset: pheno_slim synonym: "branchial cleft" RELATED [Wikipedia:Pharyngeal_groove] synonym: "branchial groove" RELATED [AAO:0010623, Wikipedia:Pharyngeal_groove] synonym: "gill cleft" NARROW [] synonym: "Kiemenspalten" RELATED [] synonym: "pharyngeal ectodermal cleft" RELATED [] synonym: "pharyngeal groove" BROAD [Wikipedia:Pharyngeal_groove] synonym: "pharyngeal groove ectoderm" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pharyngeal slit" RELATED INCONSISTENT [] synonym: "sulcus pharyngei" RELATED LATIN [Wikipedia:Pharyngeal_groove] xref: AAO:0010623 xref: EMAPA:32750 xref: FMA:295672 xref: NCIT:C34250 xref: UMLS:C1280559 {source="ncithesaurus:Pharyngeal_Groove"} xref: Wikipedia:Pharyngeal_groove is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006846 {source="EHDAA2"} ! surface groove relationship: adjacent_to UBERON:0004117 ! pharyngeal pouch relationship: overlaps UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0016545 ! pharyngeal ectoderm property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/20/Kiemenbogen.jpg" xsd:anyURI property_value: editor_note "Note we use overlaps as the relationship to the arches" xsd:string property_value: UBPROP:0000012 "EMAPA distinguishes between the groove ectoderm and epithelium, with the latter arising after the former" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0005881 name: autopodial extension namespace: uberon def: "A subdivision of the autopod that corresponds to one or more bones arranged in series branching from the main limb axis." [http://orcid.org/0000-0002-6601-2165] comment: encompasses digits and prepollex. requires review synonym: "digit or predigit" RELATED [] synonym: "limb outgrowth" RELATED [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0005884 name: hyoid arch skeleton namespace: uberon def: "A subdivision of skeleton that supports pharyngeal arch 2." [OBOL:automatic] synonym: "hyoid arch" RELATED INCONSISTENT [TAO:0001276] synonym: "hyoid arch skeleton" EXACT [ZFA:0001276] synonym: "hyoid bars" NARROW [TAO:0001276] synonym: "pharyngeal arch 2 skeleton" EXACT [ZFA:0001276] synonym: "visceral arch 2" RELATED INCONSISTENT [TAO:0001276] xref: AAO:0000665 xref: AAO:0010370 xref: TAO:0001276 xref: XAO:0003177 xref: ZFA:0001276 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010912 ! subdivision of skeleton relationship: develops_from UBERON:0003066 {source="cjm"} ! pharyngeal arch 2 relationship: part_of UBERON:0008895 {source="ZFA"} ! splanchnocranium property_value: UBPROP:0000012 "it's not clear where AAO:'hyobranchial skeleton' belongs" xsd:string {external_ontology="AAO"} [Term] id: UBERON:0005891 name: coelomic epithelium namespace: uberon def: "The epithelial lining of the surface of the coelom." [Wikipedia:Coelomic_epithelium, XAO:0000329] synonym: "celomic epithelium" EXACT [] synonym: "germinal epithelium of Waldeyer" EXACT [Wikipedia:Coelomic_epithelium] xref: Wikipedia:Coelomic_epithelium xref: XAO:0000329 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000483 ! epithelium relationship: has_developmental_contribution_from UBERON:0004871 {source="XAO"} ! somatic layer of lateral plate mesoderm relationship: has_developmental_contribution_from UBERON:0004872 {source="XAO"} ! splanchnic layer of lateral plate mesoderm relationship: located_in UBERON:0002323 ! coelemic cavity lumen relationship: part_of UBERON:0011997 ! coelom property_value: UBPROP:0000012 "EHDAA2:0004049 used to be called 'coelomic epithelium' but is now 'gonadal ridge mesothelium'" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0005893 name: leg bone namespace: uberon def: "A bone that is part of the region of the hindlimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia. Counter-examples: any pes phalanx." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: human_reference_atlas xref: EMAPA:37304 {source="MA:th"} xref: MA:0000670 xref: MESH:D007867 is_a: UBERON:0003464 ! hindlimb bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000978 ! leg relationship: part_of UBERON:0000978 ! leg property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0005897 name: manus bone namespace: uberon def: "A bone that is part of the manus skeleton. Note that this includes the carpal bones." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "bone of hand" EXACT [] synonym: "bone of hand skeleton" EXACT [] synonym: "bone of manus" EXACT [] synonym: "bone of pectoral limb autopod" EXACT [] synonym: "bone of pectoral limb autopodium" EXACT [] synonym: "forelimb autopod bone" EXACT [] synonym: "forelimb autopodium bone" EXACT [] synonym: "hand bone" EXACT [MA:0000619] xref: EMAPA:35391 xref: MA:0000619 xref: SCTID:426741001 is_a: UBERON:0008962 ! forelimb bone is_a: UBERON:0011250 ! autopod bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0001442 ! skeleton of manus property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0005899 name: pes bone namespace: uberon def: "A bone that is part of the pes skeleton." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "bone of foor proper or tarsal skeleton" EXACT [] synonym: "bone of foot" EXACT [] synonym: "bone of pedal skeleton" EXACT [] synonym: "bone of pes" EXACT [] synonym: "foot bone" EXACT [MA:0000643] xref: EMAPA:35354 xref: GAID:192 xref: MA:0000643 xref: MESH:D005529 xref: NCIT:C13068 xref: SCTID:361371005 xref: UMLS:C0016505 {source="ncithesaurus:Foot_Bone"} is_a: UBERON:0003464 ! hindlimb bone is_a: UBERON:0011250 ! autopod bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0001445 ! skeleton of pes property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0005902 name: occipital region namespace: uberon def: "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles." [TAO:0001414, UBERONREF:0000007] synonym: "back of head" RELATED [FMA:49187] synonym: "basicranial region" EXACT [ZFA:0001414] synonym: "occipital part of head" EXACT [FMA:49187] synonym: "occipital region of head" EXACT [FMA:49187] xref: AAO:0010199 xref: BTO:0004675 xref: FMA:49187 xref: neuronames:2431 xref: SCTID:362618001 xref: TAO:0001414 xref: XAO:0003173 xref: ZFA:0001414 is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0003128 ! cranium property_value: editor_note "TODO - check" xsd:string property_value: UBPROP:0000001 "An anatomical cluster that is located in the posterior region of the neurocranium and forms the margin of the foramen margin and occipital condyles.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010199", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occiptal condyle.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001414", ontology="TAO", source="TAO:MAH"} [Term] id: UBERON:0005903 name: duct of seminal vesicle namespace: uberon def: "Each seminal vesicle consists of a single tube, coiled upon itself, and giving off several irregular cecal diverticula; the separate coils, as well as the diverticula, are connected together by fibrous tissue. When uncoiled, the tube is about the diameter of a quill, and varies in length from 10 to 15 cm.; it ends posteriorly in a cul-de-sac; its anterior extremity becomes constricted into a narrow straight duct called the excretory duct of seminal gland (or duct of the seminal vesicle), which joins with the corresponding ductus deferens to form the ejaculatory duct[WP]." [Wikipedia:Excretory_duct_of_seminal_gland] synonym: "ductus excretorius (vesicula seminalis)" EXACT [FMA:19473] synonym: "ductus excretorius glandulae vesiculosae" EXACT LATIN [FMA:19473, FMA:TA] synonym: "ductus excretorius glandulae vesiculosae" RELATED LATIN [Wikipedia:Excretory_duct_of_seminal_gland] synonym: "excretory duct of seminal gland" EXACT [FMA:19473] synonym: "seminal vesicle duct" EXACT [FMA:19473] xref: EMAPA:29282 xref: FMA:19473 xref: SCTID:279675008 xref: Wikipedia:Excretory_duct_of_seminal_gland is_a: UBERON:0000025 ! tube is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005904 ! duct of male reproductive system intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: channel_for UBERON:0010143 ! seminal vesicle fluid relationship: channels_into UBERON:0000999 ! ejaculatory duct relationship: part_of UBERON:0000998 ! seminal vesicle property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray1160.png" xsd:anyURI [Term] id: UBERON:0005904 name: duct of male reproductive system namespace: uberon def: "Any of the ducts that are part of a male reproductive system." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: UBERON:0000058 ! duct is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0000079 ! male reproductive system relationship: part_of UBERON:0000079 ! male reproductive system property_value: IAO:0000232 "this class groups the individual ducts in a variety of species" xsd:string [Term] id: UBERON:0005906 name: serous sac namespace: uberon def: "Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]." [FMA:9689, https://github.com/obophenotype/uberon/issues/86] comment: See notes for serous membrane xref: EMAPA:16060 xref: FMA:9689 xref: MA:0000005 xref: SCTID:362890006 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000062 ! organ relationship: has_part UBERON:0000042 ! serous membrane relationship: has_part UBERON:0002553 ! anatomical cavity relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall [Term] id: UBERON:0005911 name: endo-epithelium namespace: uberon def: "Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA]." [FMA:69065] synonym: "endoderm-derived epithelium" EXACT [] synonym: "endoepithelium" EXACT [] xref: FMA:69065 is_a: UBERON:0000483 ! epithelium is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_from UBERON:0000925 ! endoderm [Term] id: UBERON:0005913 name: zone of bone organ namespace: uberon synonym: "bone organ zone" EXACT [FMA:10483] xref: FMA:10483 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034944 {source="FMA"} ! zone of organ relationship: composed_primarily_of UBERON:0002481 ! bone tissue relationship: part_of UBERON:0001474 ! bone element [Term] id: UBERON:0005928 name: external naris namespace: uberon def: "A naris that provides one of the small external openings of the head that give passage to air for breathing." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Nostril] subset: pheno_slim subset: vertebrate_core synonym: "anterior nares" RELATED PLURAL [VHOG:0000544] synonym: "anterior naris" RELATED [ZFA:0001427] synonym: "blowhole" NARROW [Wikipedia:Blowhole_(anatomy)] synonym: "external nares" EXACT PLURAL [] synonym: "naris" BROAD [ZFA:0000550] synonym: "nostril" EXACT [FMA:59645, XAO:0003033] xref: AAO:0000024 xref: AAO:0000983 xref: AAO:0010358 xref: EHDAA2:0001275 xref: EHDAA:9085 xref: EMAPA:17848 xref: FMA:59645 xref: MA:0001320 xref: NCIT:C33178 xref: SCTID:276165005 xref: TAO:0000550 xref: UMLS:C0595944 {source="ncithesaurus:Nostril"} xref: VHOG:0000544 xref: Wikipedia:Nostril xref: XAO:0003033 xref: ZFA:0000550 is_a: UBERON:0000003 ! naris is_a: UBERON:0003102 {source="ZFA"} ! surface structure is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000003 ! naris intersection_of: connects UBERON:0001707 ! nasal cavity intersection_of: connects UBERON:0013514 ! space surrounding organism relationship: capable_of_part_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: connects UBERON:0013514 ! space surrounding organism relationship: contributes_to_morphology_of UBERON:0000004 ! nose relationship: part_of UBERON:0000004 ! nose property_value: UBPROP:0000001 "Hole on the nasal capsule that connects the nasal cavity with the exterior.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000024", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: subclass nasal opening (AAO:0000316)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000024", ontology="AAO"} property_value: UBPROP:0000003 "In a tetrapod, the nasal sac has an external naris (homologous with the anterior naris of the fish) (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000544", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.257 and Figure 7.27", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Fish have two pairs of external nostrils." xsd:string [Term] id: UBERON:0005944 name: axial skeleton plus cranial skeleton namespace: uberon def: "Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]." [FMA:71221, https://github.com/obophenotype/uberon/issues/44, https://github.com/obophenotype/uberon/wiki/The-axial-skeleton, VSAO:0000056, Wikipedia:Axial_skeleton] subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "skeleton axiale" RELATED LATIN [Wikipedia:Axial_skeleton] xref: AAO:0000963 xref: EMAPA:17214 xref: EMAPA:18043 xref: MA:0000308 xref: NCIT:C32172 xref: SCTID:361725000 xref: UMLS:C0222645 {source="ncithesaurus:Axial_Skeleton"} xref: VSAO:0000056 xref: Wikipedia:Axial_skeleton xref: XAO:0004011 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010912 ! subdivision of skeleton relationship: connected_to UBERON:0002091 {gci_relation="part_of", gci_filler="NCBITaxon:7776"} ! appendicular skeleton relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system relationship: develops_from UBERON:0003089 ! sclerotome relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: part_of UBERON:0011137 ! axial skeletal system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8b/Axial_skeleton_diagram.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI property_value: UBPROP:0000001 "Skeletal subdivision of the central body axis including the cranium, vertebrae, notochord, ribs, and sternum.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000056", ontology="VSAO", source="PSPUB:0000170"} [Term] id: UBERON:0005945 name: neurocranial trabecula namespace: uberon subset: efo_slim synonym: "neurocranial trabeculae" EXACT PLURAL [ZFA:0001321] synonym: "trabecula" BROAD SENSU [ZFA:0001321] synonym: "trabecular cartilage" BROAD [ZFA:0001321] xref: EFO:0003677 xref: TAO:0001321 xref: ZFA:0001321 is_a: UBERON:0000440 ! trabecula is_a: UBERON:0003932 {source="ZFA"} ! cartilage element of chondrocranium relationship: part_of UBERON:0003112 {source="ZFA"} ! olfactory region [Term] id: UBERON:0005946 name: outflow tract of atrium namespace: uberon def: "An outflow tract that is part of a cardiac atrium." [OBOL:automatic] synonym: "outflow part of atrium" EXACT [FMA:14141] xref: FMA:14141 is_a: UBERON:0004145 ! outflow tract intersection_of: UBERON:0004145 ! outflow tract intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: continuous_with UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0002081 ! cardiac atrium [Term] id: UBERON:0005953 name: outflow part of right ventricle namespace: uberon def: "Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk." [MP:0010428] synonym: "arterial cone" RELATED [MP:0010428] synonym: "conus arteriosus" RELATED [MP:0010428] synonym: "conus arteriosus (infundibulum)" EXACT [FMA:7216] synonym: "infundibulum" BROAD [Wikipedia:Conus_arteriosus] synonym: "infundibulum of right ventricle" EXACT [FMA:7216, MP:0010428] synonym: "outflow tract of right ventricle" EXACT [FMA:7216] synonym: "pulmonary cone" RELATED [MP:0010428] synonym: "pulmonary conus" EXACT [FMA:7216] synonym: "pulmonary conus" RELATED [MP:0010428] synonym: "right ventricle pulmonary outflow tract" EXACT [MP:0010428] synonym: "right ventricular outflow tract" EXACT [MP:0010428] synonym: "RVOT" EXACT ABBREVIATION [MP:0010428] xref: EMAPA:37926 {source="MA:th"} xref: FMA:7216 xref: NCIT:C61368 xref: SCTID:244379003 xref: UMLS:C1881209 {source="ncithesaurus:Infundibulum"} is_a: UBERON:0005337 ! outflow tract of ventricle intersection_of: UBERON:0005337 ! outflow tract of ventricle intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: continuous_with UBERON:0002333 ! pulmonary trunk relationship: develops_from UBERON:0009889 {source="PMID:17276708"} ! secondary heart field relationship: part_of UBERON:0002080 ! heart right ventricle [Term] id: UBERON:0005956 name: outflow part of left ventricle namespace: uberon def: "Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta." [MP:0010429] subset: pheno_slim synonym: "aortic vestibule" EXACT [FMA:9473, MP:0010429] synonym: "heart left ventricle outflow tract" EXACT [MP:0010429] synonym: "left ventricular outflow" EXACT [FMA:9473] synonym: "left ventricular outflow tract" EXACT [HP:0011103] synonym: "LVOT" EXACT ABBREVIATION [MP:0010429] synonym: "outflow tract of left ventricle" EXACT [FMA:9473] synonym: "Sibson vestibule" EXACT [MP:0010429] synonym: "vestibulum aortae" EXACT LATIN [FMA:9473, FMA:TA] xref: EMAPA:37925 {source="MA:th"} xref: FMA:9473 xref: SCTID:264070001 xref: Wikipedia:Aortic_vestibule is_a: UBERON:0005337 ! outflow tract of ventricle intersection_of: UBERON:0005337 ! outflow tract of ventricle intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 ! heart left ventricle [Term] id: UBERON:0005965 name: outflow part of right atrium namespace: uberon def: "Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA]." [FMA:9550, FMA:FMA] synonym: "main part of right atrium" EXACT [FMA:9550] synonym: "outflow tract of right atrium" EXACT [FMA:9550] xref: FMA:9550 is_a: UBERON:0005946 ! outflow tract of atrium intersection_of: UBERON:0005946 ! outflow tract of atrium intersection_of: part_of UBERON:0002078 ! right cardiac atrium relationship: part_of UBERON:0002078 ! right cardiac atrium [Term] id: UBERON:0005966 name: outflow part of left atrium namespace: uberon def: "An outflow tract of atrium that is part of a left atrium." [OBOL:automatic] synonym: "main part of left atrium" EXACT [FMA:9551] synonym: "outflow tract of left atrium" EXACT [FMA:9551] xref: FMA:9551 is_a: UBERON:0005946 ! outflow tract of atrium intersection_of: UBERON:0005946 ! outflow tract of atrium intersection_of: part_of UBERON:0002079 ! left cardiac atrium relationship: part_of UBERON:0002079 ! left cardiac atrium [Term] id: UBERON:0005971 name: amniotic fold namespace: uberon def: "A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]." [ISBN:0073040584] subset: pheno_slim synonym: "amnionic fold" EXACT [http://placentation.ucsd.edu/glossfs.html] xref: EMAPA:16076 is_a: UBERON:0000478 ! extraembryonic structure relationship: develops_from UBERON:0004874 {source="ISBN:0073040584"} ! somatopleure relationship: only_in_taxon NCBITaxon:32524 ! Amniota [Term] id: UBERON:0005979 name: crista terminalis namespace: uberon def: "The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium." [MP:0010495] subset: pheno_slim synonym: "crista terminalis atrii dextri" EXACT LATIN [FMA:9236, FMA:TA] synonym: "crista terminalis cordis" EXACT [FMA:9236] synonym: "crista terminalis of right atrium" EXACT [FMA:9236] xref: EMAPA:37837 {source="MA:th"} xref: FMA:9236 xref: SCTID:277693004 xref: Wikipedia:Crista_terminalis is_a: UBERON:0000064 ! organ part is_a: UBERON:0004120 ! mesoderm-derived structure relationship: contributes_to_morphology_of UBERON:0002078 ! right cardiac atrium relationship: part_of UBERON:0002078 ! right cardiac atrium [Term] id: UBERON:0005983 name: heart layer namespace: uberon def: "The laminar structure of the heart." [MP:0010545] subset: non_informative subset: pheno_slim is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: part_of UBERON:0000948 ! heart relationship: contributes_to_morphology_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart [Term] id: UBERON:0005985 name: coronary vessel namespace: uberon def: "Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation." [MP:0010551] subset: pheno_slim xref: MESH:D003331 xref: Wikipedia:Coronary_circulation is_a: UBERON:0000055 ! vessel is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000055 ! vessel intersection_of: part_of UBERON:0000948 ! heart relationship: contributes_to_morphology_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: editor_note "TODO - change relation from part_of" xsd:string [Term] id: UBERON:0005988 name: atrium myocardial trabecula namespace: uberon def: "The supporting bundles of muscular fibers lining the walls of the atrial myocardium." [MP:0010581, ZFA:0005810] subset: pheno_slim synonym: "atrial trabecula" EXACT [] synonym: "atrium myocardial trabeculae" EXACT PLURAL [MP:0010581] synonym: "trabecula of atrium" EXACT [] synonym: "trabecular layer of atrium" EXACT [] synonym: "trabecular layer of the atrium" EXACT [ZFA:0005810] xref: EMAPA:37432 {source="MA:th"} xref: ZFA:0005810 is_a: UBERON:0000440 ! trabecula is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000440 ! trabecula intersection_of: part_of UBERON:0002302 ! myocardium of atrium relationship: contributes_to_morphology_of UBERON:0002302 ! myocardium of atrium relationship: part_of UBERON:0002302 ! myocardium of atrium relationship: part_of UBERON:0004124 {source="ZFA"} ! myocardium trabecular layer [Term] id: UBERON:0005989 name: atrioventricular septum namespace: uberon def: "The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve." [MP:0010592] subset: pheno_slim synonym: "membranous atrioventricular septum" EXACT [FMA:7136] xref: EMAPA:37431 {source="MA:th"} xref: FMA:7136 xref: SCTID:280151006 xref: Wikipedia:Atrioventricular_septum is_a: UBERON:0002099 ! cardiac septum is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002099 ! cardiac septum intersection_of: adjacent_to UBERON:0002078 ! right cardiac atrium intersection_of: adjacent_to UBERON:0002084 ! heart left ventricle relationship: adjacent_to UBERON:0002078 ! right cardiac atrium relationship: adjacent_to UBERON:0002084 ! heart left ventricle relationship: develops_from UBERON:0002062 {source="PMID:15797462", source="Wikipedia"} ! endocardial cushion [Term] id: UBERON:0006002 name: vitelline artery namespace: uberon def: "The paired arteries that carry blood to the yolk sac from the dorsal aorta." [MP:0010664, Wikipedia:Vitelline_arteries] comment: Development notes:; the vitelline arteries give rise to the celiac artery, superior mesenteric artery, and inferior mesenteric artery in the adult[MP:0010664] subset: pheno_slim xref: EHDAA2:0002208 xref: EMAPA:16207 xref: Wikipedia:Vitelline_arteries is_a: UBERON:0003513 ! trunk blood vessel is_a: UBERON:0004365 ! vitelline blood vessel is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001040 ! yolk sac relationship: branching_part_of UBERON:0005805 {notes="ventral branch"} ! dorsal aorta relationship: part_of UBERON:0005805 ! dorsal aorta relationship: supplies UBERON:0001040 ! yolk sac property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/55/Gray31.png" xsd:anyURI [Term] id: UBERON:0006003 name: integumentary adnexa namespace: uberon def: "Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers." [http://code.google.com/p/caro2/issues/detail?id=5, http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "adnexae cutis" RELATED LATIN [Wikipedia:Skin_appendage] synonym: "body hair or bristle" NARROW [GO:GO] synonym: "skin adnexa" RELATED [Wikipedia:Skin_appendage] synonym: "skin adnexal structure" RELATED [] synonym: "skin appendage" RELATED [Wikipedia:Skin_appendage] xref: EMAPA:37883 {source="MA:th"} xref: Wikipedia:Skin_appendage is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002416 ! integumental system property_value: editor_note "add subclasses based on resolution of CARO tracker item. Also check: adnexal gland. Note that MP implicitly includes hypodermis." xsd:string property_value: UBPROP:0000001 "the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails[MP:0010678]" xsd:string {source="MP:0010678"} [Term] id: UBERON:0006048 name: digit 1 namespace: uberon def: "A digit that is part of a digit 1 plus metapodial segment." [OBOL:automatic] subset: pheno_slim synonym: "autopod digit 1" EXACT [] synonym: "dewclaw" NARROW SENSU [Wikipedia:Dewclaw] synonym: "digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "limb digit 1" EXACT [MA:0003023] xref: EMAPA:37285 {source="MA:th"} xref: MA:0003023 is_a: UBERON:0019221 ! digit 1 or 5 intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:5006048 ! digit 1 plus metapodial segment relationship: part_of UBERON:5006048 ! digit 1 plus metapodial segment relationship: preaxialmost_part_of UBERON:0002470 ! autopod region property_value: UBPROP:0000104 "1" xsd:nonNegativeInteger [Term] id: UBERON:0006049 name: digit 2 namespace: uberon def: "A digit that is part of a digit 2 plus metapodial segment." [OBOL:automatic] synonym: "autopod digit 2" EXACT [] synonym: "digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "limb digit 2" EXACT [] synonym: "second digit" EXACT [] xref: EMAPA:37286 {source="MA:th"} is_a: UBERON:0019222 ! digit 2, 3 or 4 intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:5006049 ! digit 2 plus metapodial segment relationship: part_of UBERON:5006049 ! digit 2 plus metapodial segment property_value: UBPROP:0000104 "2" xsd:nonNegativeInteger [Term] id: UBERON:0006050 name: digit 3 namespace: uberon def: "A digit that is part of a digit 3 plus metapodial segment." [OBOL:automatic] synonym: "autopod digit 3" EXACT [] synonym: "digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "limb digit 3" EXACT [] synonym: "third digit" EXACT [] xref: EMAPA:37287 {source="MA:th"} is_a: UBERON:0019222 ! digit 2, 3 or 4 intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:5006050 ! digit 3 plus metapodial segment relationship: part_of UBERON:5006050 ! digit 3 plus metapodial segment property_value: UBPROP:0000104 "3" xsd:nonNegativeInteger [Term] id: UBERON:0006051 name: digit 4 namespace: uberon def: "A digit that is part of a digit 4 plus metapodial segment." [OBOL:automatic] synonym: "autopod digit 4" EXACT [] synonym: "digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "fourth digit" EXACT [] synonym: "limb digit 4" EXACT [] xref: EMAPA:37288 {source="MA:th"} is_a: UBERON:0019222 ! digit 2, 3 or 4 intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:5006051 ! digit 4 plus metapodial segment relationship: part_of UBERON:5006051 ! digit 4 plus metapodial segment property_value: UBPROP:0000104 "4" xsd:nonNegativeInteger [Term] id: UBERON:0006052 name: digit 5 namespace: uberon def: "A digit that is part of a digit 5 plus metapodial segment." [OBOL:automatic] synonym: "autopod digit 5" EXACT [] synonym: "digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "digiti minimi" RELATED [] synonym: "fifth digit" EXACT [] synonym: "limb digit 5" EXACT [] xref: EMAPA:17441 xref: EMAPA:37289 {source="MA:th"} is_a: UBERON:0019221 ! digit 1 or 5 intersection_of: UBERON:0002544 ! digit intersection_of: part_of UBERON:5006052 ! digit 5 plus metapodial segment relationship: part_of UBERON:5006052 ! digit 5 plus metapodial segment relationship: postaxialmost_part_of UBERON:0002470 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! autopod region property_value: UBPROP:0000104 "5" xsd:nonNegativeInteger [Term] id: UBERON:0006056 name: posterior surface of head namespace: uberon is_a: UBERON:0036215 ! anatomical surface region intersection_of: UBERON:0036215 ! anatomical surface region intersection_of: in_posterior_side_of UBERON:0000033 ! head relationship: in_posterior_side_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0006058 name: multi-limb segment region namespace: uberon def: "A collection of two or more connected limb segments. Examples: arm (comprising stylopod and zeugopod regions)." [https://orcid.org/0000-0002-6601-2165] subset: non_informative is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010758 ! subdivision of organism along appendicular axis relationship: has_part UBERON:0002529 ! limb segment property_value: seeAlso "https://github.com/obophenotype/uberon/issues/514" xsd:anyURI [Term] id: UBERON:0006061 name: process of vertebra namespace: uberon def: "A process projection from a part of the vertebra such as centrum or arches. Examples: transverse process, diapophyses, parapophyses, and zygapophyses (both the cranial zygapophyses and the caudal zygapophyses)." [Wikipedia:Vertebral_column#Structure_of_individual_vertebrae] synonym: "spinous process" NARROW [AAO:0000739] synonym: "vertebra process" EXACT [] synonym: "vertebral process" EXACT [FMA:24530] xref: AAO:0000739 xref: FMA:24530 xref: NCIT:C116112 xref: Wikipedia:Vertebral_column#Structure_of_individual_vertebrae is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4100000 ! skeletal element projection relationship: part_of UBERON:0002412 ! vertebra [Term] id: UBERON:0006062 name: zygapophysis namespace: uberon def: "Paired processes at the cephalic and caudal ends of the neural arch. They function as interlocking structures between adjacent vertebrae, and limit dorsoventral flexion and lateral movement of the column in the trunk region[AAO]. The articular processes or zygapophyses of a vertebra, in human anatomy contain two superior and two inferior, spring from the junctions of the pedicles and laminae. These stick out of an end of a vertebra to lock with a zygapophysis on the next vertebra, to make the backbone more stable. The superior processes project upward from a lower vertebra, and their articular surfaces are directed more or less backward. The inferior processes project downward from a higher vertebra, and their articular surfaces are directed more or less forward and outward. The articular surfaces are coated with hyaline cartilage." [AAO:Pugener_and_Maglia_2008, Wikipedia:Articular_processes] subset: vertebrate_core synonym: "articular process" BROAD [Wikipedia:Articular_processes] synonym: "articular process of vertebra" EXACT HUMAN_PREFERRED [FMA:11952] synonym: "intercalarium articulating process" RELATED [TAO:0001549] synonym: "p. articularis vertebrae" RELATED LATIN [Wikipedia:Articular_processes] synonym: "processus articularis (zygapophysis)" EXACT [FMA:11952] synonym: "processus articularis vertebrae" RELATED LATIN [Wikipedia:Articular_processes] synonym: "zygapophysis" EXACT [Wikipedia:Articular_processes] xref: AAO:0000710 xref: FMA:11952 xref: SCTID:317570004 xref: TAO:0001549 xref: Wikipedia:Articular_processes xref: ZFA:0001603 is_a: UBERON:0006061 ! process of vertebra is_a: UBERON:0015212 ! lateral structure relationship: in_lateral_side_of UBERON:0002412 ! vertebra property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3e/Processusarticularissuperiorvertebrae.png" xsd:anyURI property_value: editor_note "TODO - class as endochondral bone, check species" xsd:string property_value: UBPROP:0000001 "Paired processes at the cephalic and caudal ends of the neural arch. They function as interlocking structures between adjacent vertebrae, and limit dorsoventral flexion and lateral movement of the column in the trunk region.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000710", ontology="AAO", source="AAO:Pugener_and_Maglia_2008"} [Term] id: UBERON:0006063 name: cartilaginous neural arch namespace: uberon def: "One of the cartilaginous structures surrounding the embryonic spinal cord, formed by the dorsal growth of the dorsolateral arcualia; it is the primordium of the vertebral arch." [BTO:0001763] synonym: "neural arch primordium" RELATED [] xref: BTO:0001763 is_a: UBERON:0010358 ! arch of centrum of vertebra relationship: has_part UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0006067 name: musculature of hindlimb zeugopod namespace: uberon def: "Any collection of muscles that is part of a hindlimb zeugopod." [OBOL:automatic] subset: pheno_slim synonym: "leg musculature" EXACT [FMA:50211] synonym: "muscle group of leg" EXACT [FMA:50211] synonym: "set of muscles of leg" EXACT [FMA:50211] xref: FMA:50211 is_a: UBERON:0004466 ! musculature of leg intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0003823 ! hindlimb zeugopod [Term] id: UBERON:0006068 name: bone of tail namespace: uberon def: "A bone that is part of a post-anal tail." [OBOL:automatic] subset: pheno_slim synonym: "tail bone" RELATED [MA:0000696] synonym: "tail vertebra" RELATED [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:18042 xref: MA:0000696 is_a: UBERON:0001474 ! bone element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0007812 ! post-anal tail property_value: UBPROP:0000012 "MA has distinct classes for 'tail bone', 'caudal vertebra' and 'coccygeal vertebra' but these may all be equivalent. This class may be obsoleted in future." xsd:string {external_ontology="MA"} [Term] id: UBERON:0006071 name: caudal region namespace: uberon def: "Subdivision of an organism along anterior-posterior axis that is the posteriormost region, extending past the anus (or cloaca, if present), consisting of a tail in some fully formed chordates (or a tail bud in embryos). In animals that have a sacral region, this is the region immediately posterior to this." [http://orcid.org/0000-0002-6601-2165] synonym: "post-anal caudal region" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "post-anal tail region" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "postsacral region" RELATED [AAO:0000082] synonym: "tail region" RELATED [AAO:0000082] xref: XAO:0000087 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: has_skeleton UBERON:0006076 ! caudal region of vertebral column relationship: part_of UBERON:0000154 ! posterior region of body relationship: posterior_to UBERON:0001245 ! anus property_value: UBPROP:0000008 "This region is reduced in humans and corresponds to the coccyx" xsd:string property_value: UBPROP:0000012 "We follow XAO is distinguishing the tail region from the tail; the tail bud is part of the tail region; the tail starts after the tail bud" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0006072 name: cervical region of vertebral column namespace: uberon def: "That portion of the spine comprising the cervical vertebrae. The neck area of the spine." [http://medical-dictionary.thefreedictionary.com/] subset: pheno_slim synonym: "axial skeleton cervical region" EXACT [MA:0003154] synonym: "cervical skeleton" EXACT [EHDAA2:0000238] synonym: "cervical spinal column" EXACT [FMA:24138] synonym: "cervical spine" EXACT [FMA:24138] synonym: "cervical vertebrae series" EXACT [] synonym: "cervical vertebral column" EXACT [FMA:24138] synonym: "skeletal system of neck" RELATED [FMA:24138] xref: AAO:0000092 xref: BTO:0004148 xref: EHDAA2:0000238 xref: EHDAA:5051 xref: EMAPA:17215 xref: FMA:24138 xref: MA:0003154 xref: NCIT:C69313 xref: SCTID:260488005 xref: UMLS:C0728985 {source="ncithesaurus:Cervical_Spine"} is_a: UBERON:0006077 ! subdivision of vertebral column intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0005434 ! cervical region relationship: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0012477 {source="FMA"} ! dorsal part of neck relationship: subdivision_of UBERON:0005434 ! cervical region property_value: UBPROP:0000001 "Anterior region of the vertebral column consisting of one to 19 or 20 vertebrae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000092", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} [Term] id: UBERON:0006073 name: thoracic region of vertebral column namespace: uberon def: "That part of the spine comprising the thoracic vertebrae." [http://medical-dictionary.thefreedictionary.com/] subset: pheno_slim synonym: "axial skeleton thoracic region" EXACT [MA:0003155] synonym: "columna vertebralis thoracicus" EXACT [FMA:9140] synonym: "thoracic spine" EXACT [FMA:9140] synonym: "thoracic vertebrae series" EXACT [] synonym: "thoracic vertebral column" EXACT [FMA:9140] xref: AAO:0000612 xref: BTO:0004150 xref: EHDAA:5063 xref: EMAPA:17396 xref: FMA:9140 xref: MA:0003155 xref: NCIT:C69315 xref: SCTID:243931006 xref: UMLS:C0581269 {source="ncithesaurus:Thoracic_Spine"} is_a: UBERON:0006077 ! subdivision of vertebral column intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0008231 {source="FMA"} ! dorsal thoracic segment of trunk relationship: part_of UBERON:0014477 ! thoracic skeleton relationship: subdivision_of UBERON:0000915 ! thoracic segment of trunk property_value: UBPROP:0000001 "Region of the vertebral column between the atlas and the sacrum consisting of seven to 285 vertebrae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000612", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} [Term] id: UBERON:0006074 name: lumbar region of vertebral column namespace: uberon def: "Subdivision of vertebral column that corresponds to the lumbar subdivision of the body, containing the lumbar vertebrae." [UBERONREF:0000006] subset: pheno_slim synonym: "axial skeleton lumbar region" EXACT [MA:0003156] synonym: "lumbar skeleton" EXACT [EHDAA2:0001037] synonym: "lumbar spine" EXACT [BTO:0004147] synonym: "lumbar vertebrae series" EXACT [] synonym: "lumbar vertebral column" EXACT [FMA:16203] xref: BTO:0004147 xref: EHDAA2:0001037 xref: EHDAA:5055 xref: EMAPA:17393 xref: FMA:16203 xref: GAID:31 xref: MA:0003156 xref: NCIT:C69314 xref: SCTID:243932004 is_a: UBERON:0006077 ! subdivision of vertebral column intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0005462 ! lower back relationship: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0005462 ! lower back relationship: subdivision_of UBERON:0005462 ! lower back property_value: UBPROP:0000007 "lumbar" xsd:string [Term] id: UBERON:0006075 name: sacral region of vertebral column namespace: uberon def: "Subdivision of vertebral column that corresponds to the sacral subdivision of the body, containing the sacral vertebrae or sacrum." [UBERONREF:0000006] synonym: "axial skeleton sacral region" EXACT [MA:0003157] synonym: "sacral skeleton" EXACT [EHDAA2:0001772] synonym: "sacral vertebrae series" EXACT [] synonym: "sacrum" NARROW [] xref: AAO:0000724 xref: EHDAA2:0001772 xref: EHDAA:5059 xref: EMAPA:17676 xref: GAID:32 xref: MA:0003157 xref: NCIT:C33508 xref: Wikipedia:Sacrum is_a: UBERON:0006077 ! subdivision of vertebral column intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0005473 ! sacral region relationship: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0005473 ! sacral region relationship: subdivision_of UBERON:0005473 ! sacral region property_value: UBPROP:0000001 "Region of the vertebral column represented by one or two vertebrae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000724", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} property_value: UBPROP:0000008 "In adult humans, the sacral skeleton is fused and called the sacrum" xsd:string [Term] id: UBERON:0006076 name: caudal region of vertebral column namespace: uberon def: "Subdivision of vertebral column that corresponds to the caudal subdivision of the body, containing the caudal vertebrae." [UBERONREF:0000006] synonym: "axial skeleton tail region" EXACT [MA:0003158] synonym: "caudal region" RELATED [AAO:0000082] synonym: "caudal skeleton" EXACT [UBERONREF:0000006] synonym: "caudal vertebrae series" EXACT [http://purl.bioontology.org/ontology/provisional/a047a2d5-418f-4d9c-ad21-ee0b7c29c29d] synonym: "postsacral region" RELATED [AAO:0000082] synonym: "tail region" RELATED [AAO:0000082] xref: AAO:0000082 xref: EMAPA:18043 xref: MA:0003158 is_a: UBERON:0006077 ! subdivision of vertebral column intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: subdivision_of UBERON:0006071 ! caudal region relationship: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0006071 ! caudal region relationship: subdivision_of UBERON:0006071 ! caudal region property_value: UBPROP:0000001 "Region of the vertebral column posterior to the caudal-sacral region, that may consists of two or three to more than 100 vertebrae. These vertebrae exhibit a gradual reduction in the sizes of their transverse processes and zygapophyses, but these structures are never entirely absent. All caudal vertebrae bear haemal arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000082", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} property_value: UBPROP:0000012 "in AAO, this is posterior to the caudal-sacral region" xsd:string {external_ontology="AAO"} [Term] id: UBERON:0006077 name: subdivision of vertebral column namespace: uberon def: "A collection of all skeletal elements in some subdivision of the vertebral column." [https://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "subdivision of vertebral skeleton" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "vertebrae series" EXACT [] synonym: "vertebral column subdivision" EXACT [FMA:16201] synonym: "vertebral region" RELATED [] synonym: "vertebral series" EXACT [] synonym: "vertebral subdivision" RELATED [] xref: FMA:16201 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 ! subdivision of skeletal system intersection_of: UBERON:0000075 ! subdivision of skeletal system intersection_of: subdivision_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum relationship: subdivision_of UBERON:0001130 ! vertebral column [Term] id: UBERON:0006134 name: nerve fiber namespace: uberon def: "A threadlike extension of a nerve cell and consists of an axon and myelin sheath (if it is myelinated) in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system (CNS), myelin by oligodendroglia cells is formed. Schwann cells form myelin in the peripheral nervous system (PNS). Schwann cells also make a thin covering in an axon without myelin (in the PNS). A peripheral nerve fiber contains an axon, myelin sheath, schwann cells and its endoneurium. There are no endoneurium and schwann cells in the central nervous system." [Wikipedia:Nervous_system_fiber] subset: human_reference_atlas synonym: "nerve fibers" RELATED PLURAL [BAMS:nfi] synonym: "nerve fibre" EXACT [FMA:5914] synonym: "neurofibra" EXACT LATIN [FMA:5914, FMA:TA] synonym: "neurofibra" RELATED LATIN [Wikipedia:Nerve_fiber] synonym: "neurofibrum" EXACT [FMA:5914] xref: BAMS:nfi xref: FMA:5914 xref: MESH:D009412 xref: SCTID:88545005 xref: Wikipedia:Nervous_system_fiber is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005162 ! multi cell part structure union_of: UBERON:0006135 ! myelinated nerve fiber union_of: UBERON:0006136 ! unmyelinated nerve fiber relationship: extends_fibers_into CL:0000540 ! neuron relationship: has_part GO:0030424 ! axon relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001019 ! nerve fasciculus property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "neurofibrous" xsd:string [Term] id: UBERON:0006135 name: myelinated nerve fiber namespace: uberon def: "Axons of neurons encased in a lipoproteinaceous material called myelin. (MeSH)." [ncithesaurus:Myelinated_Nerve_Fiber] subset: pheno_slim xref: FMA:5915 xref: GAID:745 xref: MESH:D009413 xref: NCIT:C12627 xref: SCTID:362296008 xref: UMLS:C0027750 {source="ncithesaurus:Myelinated_Nerve_Fiber"} is_a: UBERON:0006134 ! nerve fiber intersection_of: UBERON:0006134 ! nerve fiber intersection_of: has_part GO:0043209 ! myelin sheath disjoint_from: UBERON:0006136 ! unmyelinated nerve fiber relationship: has_part GO:0043209 ! myelin sheath relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: editor_note "consider adding link to UBERON:0002316 ! white matter of neuraxis" xsd:string property_value: RO:0002161 NCBITaxon:117569 property_value: RO:0002161 NCBITaxon:7762 property_value: RO:0002175 NCBITaxon:7776 property_value: UBPROP:0000008 "http://www1.pbrc.hawaii.edu/~danh/MyelinEvolution/evolution.html, http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=6134604, Wikipedia:Myelin#Invertebrate_myelin" xsd:string [Term] id: UBERON:0006136 name: unmyelinated nerve fiber namespace: uberon subset: human_reference_atlas synonym: "non-myelinated nerve fiber" EXACT [FMA:5916] xref: FMA:5916 xref: GAID:767 xref: MESH:D036421 xref: NCIT:C33835 xref: SCTID:46920005 xref: UMLS:C0501409 {source="ncithesaurus:Unmyelinated_Nerve_Fiber"} is_a: UBERON:0006134 ! nerve fiber property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0006170 name: mesonephric capsule namespace: uberon def: "The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." [DOI:10.1371/journal.pone.0099864, GO:0061285, GOC:mtg_kidney_jan10] is_a: UBERON:0002015 ! kidney capsule is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0002015 ! kidney capsule intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0006207 name: aortico-pulmonary spiral septum namespace: uberon alt_id: UBERON:0005999 def: "The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions." [MP:0010650, Wikipedia:Aorticopulmonary_septum] subset: emapa_ehdaa2 subset: pheno_slim synonym: "aortic septum" RELATED [Wikipedia:Aorticopulmonary_septum] synonym: "aortico-pulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum] synonym: "aorticopulmonary septum" EXACT [Wikipedia:Aorticopulmonary_septum] synonym: "septum aorticopulmonale" EXACT LATIN [Wikipedia:Aorticopulmonary_septum] synonym: "spiral septum" RELATED [Wikipedia:Aorticopulmonary_septum] xref: CALOHA:TS-2409 xref: EHDAA2:0000136 xref: EHDAA:2592 xref: EMAPA:16827 xref: VHOG:0000502 xref: Wikipedia:Aorticopulmonary_septum is_a: UBERON:0004142 ! outflow tract septum is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0002099 ! cardiac septum intersection_of: adjacent_to UBERON:0002333 ! pulmonary trunk intersection_of: adjacent_to UBERON:0005805 ! dorsal aorta relationship: adjacent_to UBERON:0002333 ! pulmonary trunk relationship: adjacent_to UBERON:0005805 ! dorsal aorta relationship: develops_from UBERON:0000095 {source="PMID:6844926", source="Wikipedia"} ! cardiac neural crest property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b9/Gray470.png" xsd:anyURI [Term] id: UBERON:0006208 name: auditory hillocks namespace: uberon def: "A collection of protruberances derived from pharyngeal arches 1 and 2 that develop into the folds of the pinna and gradually shift upwards and backwards to their final position on the head." [Wikipedia:Pinna_(anatomy)#Development] subset: emapa_ehdaa2 synonym: "auditory hillock of Hiss" EXACT [] synonym: "auditory tubercles" RELATED INCONSISTENT [VHOG:0001364] synonym: "auricular hillock" RELATED [] synonym: "hillock of Hiss" RELATED [] xref: EHDAA2:0000155 xref: EHDAA:4685 xref: EMAPA:17280 xref: NCIT:C34110 xref: VHOG:0001364 is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0001691 ! external ear [Term] id: UBERON:0006210 name: body-wall mesenchyme namespace: uberon subset: emapa_ehdaa2 xref: EHDAA2:0000179 xref: EHDAA:3217 xref: EMAPA:16893 is_a: UBERON:0003104 ! mesenchyme relationship: part_of UBERON:0000309 ! body wall [Term] id: UBERON:0006211 name: buccopharyngeal membrane namespace: uberon def: "The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx." [MP:0012521] subset: emapa_ehdaa2 subset: pheno_slim synonym: "oral membrane" RELATED [MP:0012521] synonym: "oral plate" RELATED [MP:0012521] synonym: "oropharyngeal membrane" RELATED [Wikipedia:Buccopharyngeal_membrane] synonym: "pharyngeal membrane" RELATED INCONSISTENT [MP:0012521] xref: EHDAA2:0000189 xref: EHDAA:536 xref: EMAPA:16259 xref: FMA:313607 xref: SCTID:361412007 xref: VHOG:0000380 xref: Wikipedia:Buccopharyngeal_membrane is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003037 ! septum relationship: has_developmental_contribution_from UBERON:0000924 ! ectoderm relationship: has_developmental_contribution_from UBERON:0000925 ! endoderm relationship: overlaps UBERON:0000930 ! stomodeum relationship: overlaps UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0006264 {source="EHDAA2"} ! mouth-foregut junction property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/93/Gray977.png" xsd:anyURI [Term] id: UBERON:0006213 name: carpus cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a carpal bone." [OBOL:automatic] synonym: "carpal cartilage condensation" RELATED [EMAPA:18102] xref: EHDAA2:0000221 xref: EHDAA:8544 xref: EMAPA:18102 xref: VHOG:0001123 is_a: UBERON:0003319 ! mesenchyme of carpal region is_a: UBERON:0005863 ! cartilaginous condensation is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0010377 ! mesenchyme from somatopleure is_a: UBERON:0015049 ! carpus endochondral element intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: has_potential_to_develop_into UBERON:0001435 ! carpal bone relationship: develops_from UBERON:0006214 ! carpus pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0001435 ! carpal bone [Term] id: UBERON:0006214 name: carpus pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a carpal bone." [OBOL:automatic] synonym: "carpal pre-cartilage condensation" RELATED [EMAPA:17724] xref: EHDAA2:0000222 xref: EHDAA:6324 xref: EMAPA:17724 xref: VHOG:0000955 is_a: UBERON:0003319 ! mesenchyme of carpal region is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0009523 ! mesenchyme of handplate is_a: UBERON:0015049 ! carpus endochondral element intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0001435 ! carpal bone relationship: develops_from UBERON:0003319 ! mesenchyme of carpal region relationship: has_potential_to_develop_into UBERON:0001435 ! carpal bone relationship: part_of UBERON:0009523 ! mesenchyme of handplate [Term] id: UBERON:0006217 name: cloacal membrane namespace: uberon def: "The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings." [MP:0011837, MP:anna, Wikipedia:Cloacal_membrane] subset: emapa_ehdaa2 subset: pheno_slim synonym: "embryonic cloacal membrane" EXACT [] synonym: "membrana cloacalis" RELATED LATIN [Wikipedia:Cloacal_membrane] xref: EHDAA2:0000257 xref: EHDAA:214 xref: EHDAA:2933 xref: EMAPA:16832 xref: FMA:295525 xref: NCIT:C34128 xref: SCTID:308826008 xref: UMLS:C0231056 {source="ncithesaurus:Cloacal_Membrane"} xref: VHOG:0001198 xref: Wikipedia:Cloacal_membrane is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000158 ! membranous layer relationship: contributes_to_morphology_of UBERON:0000163 ! embryonic cloaca relationship: develops_from UBERON:0004341 {source="Wikipedia"} ! primitive streak relationship: has_developmental_contribution_from UBERON:0000924 ! ectoderm relationship: has_developmental_contribution_from UBERON:0000925 ! endoderm relationship: part_of UBERON:0000163 ! embryonic cloaca property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d2/Gray991.png" xsd:anyURI property_value: UBPROP:0000001 "A membrane that separates the proctodeum and the hindgut in the early embryo. [Evolution, Fourth_Edition_(2006)_McGraw-Hill, Function, Vertebrates:_Comparative_Anatomy, p.497, see_Kardong_KV][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001198", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In mammals, the cloaca exists as an embryonic structure that undergoes septation to become distinct urethral, anal, and genital orifices.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001198", ontology="VHOG", source="PMID:11830557 De Santa Barbara P, Roberts DJ, Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13. Development (2002)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006218 name: common atrial chamber namespace: uberon subset: emapa_ehdaa2 xref: EHDAA:1267 xref: EMAPA:16342 xref: RETIRED_EHDAA2:0000268 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0002081 ! cardiac atrium [Term] id: UBERON:0006219 name: deltoid pre-muscle mass namespace: uberon subset: emapa_ehdaa2 xref: EHDAA2:0000340 xref: EHDAA:6002 xref: EMAPA:17749 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle [Term] id: UBERON:0006224 name: elbow joint primordium namespace: uberon subset: emapa_ehdaa2 xref: EHDAA2:0000431 xref: EHDAA:8483 xref: EMAPA:17710 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium relationship: has_potential_to_develop_into UBERON:0001490 ! elbow joint relationship: part_of UBERON:0003318 ! mesenchyme of elbow [Term] id: UBERON:0006227 name: ethmoid bone primordium namespace: uberon subset: emapa_ehdaa2 xref: EHDAA2:0000456 xref: EHDAA:8363 xref: EMAPA:18023 xref: FMA:312597 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0001679 ! ethmoid bone relationship: develops_from UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest relationship: has_potential_to_develop_into UBERON:0001679 ! ethmoid bone relationship: part_of UBERON:0002517 {source="FMA"} ! basicranium relationship: part_of UBERON:0011241 {source="AAO"} ! ethmoid region property_value: editor_note "consider obsoleting, the ethmoid is endochondral?" xsd:string [Term] id: UBERON:0006232 name: facio-acoustic VII-VIII preganglion complex namespace: uberon subset: emapa_ehdaa2 synonym: "facio-acoustic preganglion complex" RELATED [EMAPA:16660] xref: EHDAA:1477 xref: EMAPA:16660 xref: RETIRED_EHDAA2:0000496 xref: VHOG:0000715 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0005565 ! facio-acoustic neural crest relationship: part_of UBERON:0001714 {source="EHDAA2"} ! cranial ganglion [Term] id: UBERON:0006233 name: female genital tubercle namespace: uberon def: "A differentiated genital tubercle that is part of a female reproductive system." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "genital tubercle of female" EXACT [EMAPA:18680] xref: EHDAA:8118 xref: EMAPA:18680 xref: RETIRED_EHDAA2:0000500 xref: VHOG:0000666 is_a: UBERON:0011757 ! differentiated genital tubercle intersection_of: UBERON:0011757 ! differentiated genital tubercle intersection_of: part_of UBERON:0000474 ! female reproductive system relationship: part_of UBERON:0005056 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! external female genitalia [Term] id: UBERON:0006234 name: femur pre-cartilage condensation namespace: uberon def: "A femur endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "femoral pre-cartilage condensation" RELATED [EMAPA:17502] xref: EHDAA2:0000508 xref: EMAPA:17502 xref: VHOG:0000951 is_a: UBERON:0005254 ! upper leg mesenchyme is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0010886 ! hindlimb pre-cartilage condensation is_a: UBERON:0015052 ! femur endochondral element intersection_of: UBERON:0015052 ! femur endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0000981 ! femur [Term] id: UBERON:0006235 name: foregut-midgut junction namespace: uberon def: "An anatomical junctions that overlaps the foregut and midgut." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000569 xref: EHDAA:526 xref: EMAPA:16363 xref: VHOG:0000291 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:1100000 ! digestive tract junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0001041 ! foregut intersection_of: connects UBERON:0001045 ! midgut relationship: connects UBERON:0001041 ! foregut relationship: connects UBERON:0001045 ! midgut relationship: part_of UBERON:0001555 ! digestive tract property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000291", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006236 name: tetrapod frontal bone primordium namespace: uberon subset: emapa_ehdaa2 synonym: "frontal bone primordium" EXACT [EHDAA2:0000577] xref: EHDAA2:0000577 xref: EHDAA:9540 xref: EMAPA:18017 xref: FMA:312589 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0000209 ! tetrapod frontal bone relationship: has_potential_to_develop_into UBERON:0000209 ! tetrapod frontal bone [Term] id: UBERON:0006238 name: future brain namespace: uberon def: "The embryonic precursor of the brain." [NLX:94995] subset: cumbo subset: efo_slim subset: emapa_ehdaa2 subset: vertebrate_core synonym: "brain rudiment" EXACT [TAO:0000146] synonym: "embryonic brain" RELATED [BTO:0004726] synonym: "encephalon" NARROW [NLX:94995] synonym: "presumptive brain" EXACT [ZFA:0000146] xref: BAMS:Enc xref: BTO:0004726 xref: EFO:0003431 xref: EHDAA:300 xref: EHDAA:830 xref: EMAPA:16089 xref: FMA:312967 xref: RETIRED_EHDAA2:0000591 xref: TAO:0000146 xref: ZFA:0000146 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0000955 ! brain relationship: part_of UBERON:0002346 ! neurectoderm property_value: UBPROP:0000001 "The embryonic precursor of the brain and the set of mature brain structures that derive from it (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"} [Term] id: UBERON:0006239 name: future central tendon namespace: uberon def: "A tendon that has the potential to develop into a central tendon." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "cranial derivative of septum transversum" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "cranial part of septum transversum" RELATED [http://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0000593 xref: EHDAA:4118 xref: EMAPA:25035 is_a: UBERON:0000043 ! tendon is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0000043 ! tendon intersection_of: has_potential_to_develop_into UBERON:0006670 ! central tendon of diaphragm relationship: develops_from UBERON:0004161 {notes="mesenchyme", region="cranial part", source="Wikipedia"} ! septum transversum relationship: has_potential_to_develop_into UBERON:0006670 ! central tendon of diaphragm relationship: part_of UBERON:0010084 {source="EHDAA2"} ! future diaphragm property_value: UBPROP:0000011 "The cranial part of the septum transversum gives rise to the central tendon of the diaphragm and is the origin of the myoblasts that invade the pleuroperitoneal folds resulting in the formation of the muscular diaphragm." xsd:string [Term] id: UBERON:0006240 name: future forebrain namespace: uberon def: "A presumptive structure that has the potential to develop into a forebrain." [OBOL:automatic] subset: efo_slim subset: emapa_ehdaa2 subset: vertebrate_core synonym: "future prosencephalon" EXACT [] synonym: "presumptive forebrain" EXACT [ZFA:0000062] synonym: "presumptive prosencephalon" EXACT [TAO:0000062] synonym: "prosencephalon" RELATED [EHDAA2:0000661] xref: BAMS:Pros xref: EFO:0003423 xref: EHDAA2:0000661 xref: EHDAA:2643 xref: EMAPA:16640 xref: TAO:0000062 xref: Wikipedia:Prosencephalon xref: ZFA:0000062 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001890 ! forebrain relationship: has_potential_to_develop_into UBERON:0001890 ! forebrain relationship: part_of UBERON:0006238 ! future brain property_value: editor_note "TODO. Add relationships to neural plate (both ZFA and EMAPA time this with the neural plate)" xsd:string [Term] id: UBERON:0006241 name: future spinal cord namespace: uberon subset: efo_slim subset: vertebrate_core synonym: "presumptive spinal cord" EXACT [ZFA:0000417] synonym: "presumptive spinal cord neural keel" EXACT [TAO:0000417] synonym: "presumptive spinal cord neural plate" EXACT [TAO:0000417] synonym: "presumptive spinal cord neural rod" EXACT [TAO:0000417] xref: EFO:0003438 xref: EHDAA2:0000674 xref: EHDAA:898 xref: EMAPA:16092 xref: EMAPA:16755 xref: TAO:0000417 xref: ZFA:0000417 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0001049 {source="EHDAA2"} ! neural tube relationship: has_potential_to_develop_into UBERON:0002240 ! spinal cord relationship: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0006242 name: gallbladder primordium namespace: uberon def: "A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops." [ISBN:0815318960, XAO:0004205] subset: emapa_ehdaa2 synonym: "gall bladder primordium" EXACT [] xref: EHDAA2:0000700 xref: EHDAA:3047 xref: EMAPA:16713 xref: XAO:0004205 is_a: UBERON:0001048 ! primordium is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0002110 ! gallbladder relationship: develops_from UBERON:0001152 {source="EHDAA2"} ! cystic duct relationship: has_potential_to_develop_into UBERON:0002110 ! gallbladder relationship: part_of UBERON:0004912 {source="EMAPA"} ! biliary bud [Term] id: UBERON:0006244 name: hip joint primordium namespace: uberon subset: emapa_ehdaa2 xref: EHDAA2:0000785 xref: EHDAA:8462 xref: EMAPA:17739 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium relationship: has_potential_to_develop_into UBERON:0001486 ! hip joint relationship: part_of UBERON:0003320 ! mesenchyme of hip [Term] id: UBERON:0006245 name: humerus cartilage element namespace: uberon def: "A humerus endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "humeral cartilage condensation" RELATED [EMAPA:17713] xref: EHDAA2:0000787 xref: EHDAA:6240 xref: EMAPA:17713 xref: VHOG:0001120 is_a: UBERON:0005258 ! upper arm mesenchyme is_a: UBERON:0005863 ! cartilaginous condensation is_a: UBERON:0010883 ! forelimb cartilage element is_a: UBERON:0015053 ! humerus endochondral element intersection_of: UBERON:0015053 ! humerus endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006246 {source="EHDAA2"} ! humerus pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0000976 ! humerus relationship: part_of UBERON:0005258 {source="EHDAA2"} ! upper arm mesenchyme [Term] id: UBERON:0006246 name: humerus pre-cartilage condensation namespace: uberon def: "A humerus endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "humeral pre-cartilage condensation" RELATED [EMAPA:17427] xref: EHDAA2:0000788 xref: EHDAA:4192 xref: EMAPA:17427 xref: VHOG:0000950 is_a: UBERON:0005258 ! upper arm mesenchyme is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015053 ! humerus endochondral element intersection_of: UBERON:0015053 ! humerus endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0000976 ! humerus relationship: part_of UBERON:0005258 {source="EHDAA2"} ! upper arm mesenchyme [Term] id: UBERON:0006247 name: iliac pre-cartilage condensation namespace: uberon def: "An iliac endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000809 xref: EHDAA:9568 xref: EMAPA:18029 xref: VHOG:0000964 is_a: UBERON:0005256 ! trunk mesenchyme is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0010377 ! mesenchyme from somatopleure is_a: UBERON:0015054 ! iliac endochondral element intersection_of: UBERON:0015054 ! iliac endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme [Term] id: UBERON:0006254 name: ischial cartilage element namespace: uberon def: "An ischial endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "ischial cartilage condensation" RELATED [EMAPA:26930] xref: EHDAA2:0000890 xref: EHDAA:9570 xref: EMAPA:26930 is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0015056 ! ischial endochondral element intersection_of: UBERON:0015056 ! ischial endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006255 {source="EHDAA2"} ! ischial pre-cartilage condensation [Term] id: UBERON:0006255 name: ischial pre-cartilage condensation namespace: uberon def: "An ischial endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000891 xref: EHDAA:7153 xref: EMAPA:18348 xref: VHOG:0000962 is_a: UBERON:0005256 ! trunk mesenchyme is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation is_a: UBERON:0010377 ! mesenchyme from somatopleure is_a: UBERON:0015056 ! ischial endochondral element intersection_of: UBERON:0015056 ! ischial endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0006256 name: knee joint primordium namespace: uberon subset: emapa_ehdaa2 xref: EHDAA2:0000897 xref: EHDAA:8467 xref: EMAPA:17740 is_a: UBERON:0001048 ! primordium is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0001485 ! knee joint relationship: part_of UBERON:0003321 ! mesenchyme of knee [Term] id: UBERON:0006260 name: lingual swellings namespace: uberon comment: the collection consisting of the two lateral swellings and the medial swelling subset: emapa_ehdaa2 synonym: "lingual swelling" RELATED [EHDAA2:0000996] xref: EHDAA2:0000996 xref: EMAPA:17186 xref: VHOG:0000449 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0010188 {source="EHDAA2"} ! protuberance relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 relationship: part_of UBERON:0010056 {source="EHDAA2"} ! future tongue property_value: UBPROP:0000001 "Primordium of the tongue; the median swelling and the distal and proximal swellings arise from the ventral aspect of the stomodeum. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000449", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/lingual+swellings"} property_value: UBPROP:0000003 "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000449", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x Iwasaki S, Evolution of the structure and function of the vertebrate tongue. J Anat (2002)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006261 name: male genital tubercle namespace: uberon def: "A differentiated genital tubercle that is part of a male reproductive system." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "genital tubercle of male" EXACT [EMAPA:17969] synonym: "penis anlage" RELATED [EMAPA:17969] xref: EHDAA:8138 xref: EMAPA:17969 xref: RETIRED_EHDAA2:0001048 xref: VHOG:0000667 is_a: UBERON:0011757 ! differentiated genital tubercle intersection_of: UBERON:0011757 ! differentiated genital tubercle intersection_of: part_of UBERON:0000079 ! male reproductive system relationship: part_of UBERON:0004053 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! external male genitalia [Term] id: UBERON:0006264 name: mouth-foregut junction namespace: uberon def: "An anatomical junctions that overlaps the mouth and foregut." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA:534 xref: EMAPA:16258 xref: RETIRED_EHDAA2:0001205 xref: VHOG:0000592 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: overlaps UBERON:0000165 ! mouth intersection_of: overlaps UBERON:0001041 ! foregut relationship: overlaps UBERON:0000165 ! mouth relationship: overlaps UBERON:0001041 ! foregut relationship: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0006267 name: notochordal plate namespace: uberon def: "The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord." [VHOG:0001212] subset: emapa_ehdaa2 xref: EHDAA2:0001278 xref: EHDAA:264 xref: EMAPA:16101 xref: NCIT:C34231 xref: UMLS:C1518429 {source="ncithesaurus:Notochordal_Plate"} xref: VHOG:0001212 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium relationship: develops_from UBERON:0006268 {source="EHDAA2"} ! notochordal process property_value: editor_note "TODO - check ordering; awaiting confirmation from JB" xsd:string property_value: UBPROP:0000001 "The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. [Carson_JL, Dehart_DB, Developmental_Dynamics_(1994)_201:_260-278, Gesteland_K_and_Schoenwolf_GC, Inagaki_T, Morphogenesis_of_the_murine_node_and_notochordal_plate, The_prechordal_plate, Vrablic_T, see_Mueller_F_and_O'Rahilly_R, the_rostral_end_of_the_notochord_and_nearby_median_features_in_staged_human_embryos._Cells_Tissues_Organs_(2003)_173:_1-20_and_Sulik_K][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001212", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006268 name: notochordal process namespace: uberon def: "A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot." [http://www.med.umich.edu/lrc/coursepages/m1/embryology/embryo/05embryonicperiod.htm] comment: The notochordal process grows cranially until it reaches the prechordal plate, the future site of the mouth. In this area the ectoderm is attached directly to the endoderm without intervening mesoderm. This area is known as the oropharyngeal membrane, and it will break down to become the mouth. At the other end of the primitive streak the ectoderm is also fused directly to the endoderm; this is known as the cloacal membrane (proctodeum), or primordial anus. subset: emapa_ehdaa2 synonym: "chordamesoderm" RELATED [] synonym: "presumptive notochord" RELATED [] xref: EHDAA2:0001279 xref: EHDAA:224 xref: EMAPA:16102 xref: FMA:293135 xref: NCIT:C34232 xref: UMLS:C1518430 {source="ncithesaurus:Notochordal_Process"} xref: VHOG:0001213 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0000924 {source="EHDAA2"} ! ectoderm relationship: only_in_taxon NCBITaxon:7711 ! Chordata [Term] id: UBERON:0006271 name: orbital fissure namespace: uberon def: "Either of two openings transmitting nerves and blood vessels to or from the orbit." [http://www.merriam-webster.com/medical/orbital%20fissure] subset: emapa_ehdaa2 xref: EHDAA2:0001328 xref: EHDAA:10648 xref: EMAPA:18717 xref: SCTID:280546005 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: part_of UBERON:0001697 ! orbit of skull relationship: part_of UBERON:0001697 ! orbit of skull [Term] id: UBERON:0006273 name: otic pit namespace: uberon alt_id: UBERON:0009123 def: "The pair of depressions of thickened otic placode epithelium, that further develops into the otic vesicles." [ISBN:0-683-40008-8, MP:0011172] subset: emapa_ehdaa2 subset: pheno_slim synonym: "otic cup" EXACT [NCBIBook:NBK53175] xref: EHDAA2:0001336 xref: EHDAA:929 xref: EMAPA:16536 xref: FMA:302911 xref: NCIT:C34238 xref: VHOG:0001147 xref: Wikipedia:Otic_pit is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0016566 {source="EHDAA2"} ! pit relationship: has_potential_to_develop_into UBERON:0003051 ! ear vesicle relationship: part_of UBERON:0003069 ! otic placode property_value: UBPROP:0000001 "A depression appearing in each otic placode, marking the beginnning of embryonic development of the internal ear. [TFD][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001147", ontology="VHOG", source="http://bgee.unil.ch/", source="http://medical-dictionary.thefreedictionary.com/Otic+pit"} [Term] id: UBERON:0006279 name: pleuroperitoneal canal namespace: uberon def: "Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity." [ISBN:0124020607, VHOG:0001505] subset: emapa_ehdaa2 synonym: "pleuroperitoneal channel" RELATED [VHOG:0001505] xref: EHDAA2:0001481 xref: EHDAA:4128 xref: EMAPA:17704 xref: EMAPA:17707 xref: SCTID:361413002 xref: VHOG:0001505 is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0003914 ! epithelial tube intersection_of: connects UBERON:0001179 ! peritoneal cavity intersection_of: connects UBERON:0002402 ! pleural cavity relationship: connects UBERON:0001179 ! peritoneal cavity relationship: connects UBERON:0002402 ! pleural cavity relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0011997 {source="EHDAA2"} ! coelom property_value: UBPROP:0000001 "Each of the canal that links the peritoneal cavity and the caudal part of a pleural cavity. [ISBN:0124020607][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001505", ontology="VHOG", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006283 name: future cardiac ventricle namespace: uberon alt_id: UBERON:0010226 def: "Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle." [ZFA:0001719] comment: The embryonic ventricle or primitive ventricle of the developing heart gives rise to the trabeculated parts of the left and right ventricles. In contrast, the smooth parts of the left and right ventricles originate from the embryological bulbus cordis. The primitive ventricle becomes divided by a septum, the septum inferius or ventricular septum, which grows upward from the lower part of the ventricle, its position being indicated on the surface of the heart by a furrow. Its dorsal part increases more rapidly than its ventral portion, and fuses with the dorsal part of the septum intermedium. For a time an interventricular foramen exists above its ventral portion, but this foramen is ultimately closed by the fusion of the aortic septum with the ventricular septum[WP] synonym: "early heart ventricle" EXACT [] synonym: "embryonic heart ventricle" EXACT [] synonym: "embryonic ventricle" BROAD [] synonym: "future heart ventricle" EXACT [] synonym: "presumptive cardiac ventricle heart tube" EXACT [ZFA:0001719] synonym: "primitive ventricle" EXACT [EHDAA2:0001531] synonym: "primitive ventricle of heart" EXACT [EMAPA:16350] synonym: "primordial cardiac ventricle" EXACT [FMA:71006] synonym: "primordial ventricle" EXACT [FMA:71006] xref: EHDAA2:0001531 xref: EMAPA:16350 xref: FMA:71006 xref: NCIT:C34160 xref: SCTID:361524003 xref: TAO:0002231 xref: Wikipedia:Embryonic_ventricle xref: ZFA:0001719 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0004141 {source="ZFA"} ! heart tube relationship: part_of UBERON:0005498 {source="EMAPA"} ! primitive heart tube [Term] id: UBERON:0006285 name: pubic pre-cartilage condensation namespace: uberon def: "A pubic endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0001574 xref: EHDAA:9572 xref: EMAPA:18349 xref: VHOG:0000965 is_a: UBERON:0005256 ! trunk mesenchyme is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation is_a: UBERON:0010377 ! mesenchyme from somatopleure is_a: UBERON:0015055 ! pubic endochondral element intersection_of: UBERON:0015055 ! pubic endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0006286 name: radius cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a radius bone." [OBOL:automatic] xref: EHDAA2:0001585 xref: EHDAA:7267 xref: EMAPA:18054 xref: VHOG:0001318 is_a: UBERON:0010883 ! forelimb cartilage element is_a: UBERON:0015001 ! radius endochondral element intersection_of: UBERON:0015001 ! radius endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010846 ! radius pre-cartilage condensation relationship: part_of UBERON:0003327 {source="EHDAA2"} ! mesenchyme of forearm [Term] id: UBERON:0006287 name: radius-ulna pre-cartilage condensation namespace: uberon def: "A radius-ulna endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] xref: EHDAA2:0001587 xref: EHDAA:4178 xref: EMAPA:17420 xref: VHOG:0000949 is_a: UBERON:0003327 ! mesenchyme of forearm is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015002 ! radius-ulna endochondral element intersection_of: UBERON:0015002 ! radius-ulna endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0003327 ! mesenchyme of forearm property_value: UBPROP:0000012 "EMAPA has a separate radius-ulna cartilage condensation." xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0006288 name: rib cartilage element namespace: uberon def: "A rib endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0001716 xref: EHDAA:8347 xref: EMAPA:17678 xref: VHOG:0001122 is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0015019 ! rib endochondral element intersection_of: UBERON:0015019 ! rib endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006289 {source="EHDAA2"} ! rib pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0002228 ! rib [Term] id: UBERON:0006289 name: rib pre-cartilage condensation namespace: uberon def: "A rib endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0001717 xref: EHDAA:6026 xref: EMAPA:17397 xref: VHOG:0000681 is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation is_a: UBERON:0015019 ! rib endochondral element intersection_of: UBERON:0015019 ! rib endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0003089 {source="EHDAA2-abduced", source="ZFA"} ! sclerotome relationship: has_potential_to_develop_into UBERON:0002228 ! rib [Term] id: UBERON:0006290 name: scapula cartilage element namespace: uberon def: "A scapula endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0001777 xref: EHDAA:8368 xref: EMAPA:18343 xref: VHOG:0001125 is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0015057 ! scapula endochondral element intersection_of: UBERON:0015057 ! scapula endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006291 {source="EHDAA2"} ! scapula pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0006849 ! scapula relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0006291 name: scapula pre-cartilage condensation namespace: uberon def: "A scapula endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0001778 xref: EHDAA:6041 xref: EMAPA:18027 xref: VHOG:0000960 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0015057 ! scapula endochondral element intersection_of: UBERON:0015057 ! scapula endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme relationship: has_potential_to_develop_into UBERON:0006849 ! scapula property_value: UBPROP:0000011 "the scapula has been shown to develop from multiple tissues, such as the dermomyotome of the somites, the mesodermal portion of the soma- topleure (a domain of the lateral plate mesoderm or LPM) and neural crest cell-derived mesenchyme (Huang et al., 2000; Matsuoka et al., 2005; Wang et al., 2005)." xsd:string {source="PMID:21455939"} [Term] id: UBERON:0006292 name: shoulder joint primordium namespace: uberon subset: emapa_ehdaa2 xref: EHDAA2:0001836 xref: EHDAA:8493 xref: EMAPA:17712 is_a: UBERON:0003322 ! mesenchyme of shoulder is_a: UBERON:0005856 {source="EHDAA2"} ! developing mesenchymal condensation relationship: develops_from UBERON:0003322 {source="EHDAA2"} ! mesenchyme of shoulder relationship: has_potential_to_develop_into UBERON:0001470 ! glenohumeral joint relationship: part_of UBERON:0003322 ! mesenchyme of shoulder property_value: UBPROP:0000012 "this is part of the forelimb skeleton in EHDAA2, but this violates part-disjointness" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0006293 name: spleen primordium namespace: uberon alt_id: UBERON:0009750 def: "A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]." [ISBN:0123747295, MP:0011263] subset: pheno_slim synonym: "left spleen primordium" NARROW [XAO:0000326] synonym: "spleen mesenchyme" EXACT [MP:0011263] synonym: "splenic mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "splenic primordium" EXACT [EHDAA2:0001904] xref: EHDAA2:0001904 xref: EHDAA:3003 xref: EMAPA:18535 xref: XAO:0000326 is_a: UBERON:0001048 {source="XAO"} ! primordium is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: develops_from UBERON:0004872 {source="XAO"} ! splanchnic layer of lateral plate mesoderm relationship: part_of UBERON:0005602 {source="EHDAA2-modified"} ! dorsal mesogastrium property_value: UBPROP:0000012 "check difference between splenic and spleen in EMAPA; note that in EHDAA2 the class 'spleen' refers to the mesenchyme" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0006304 name: future trigeminal ganglion namespace: uberon comment: See: https://github.com/obophenotype/mouse-anatomy-ontology/issues/13 and https://github.com/obophenotype/uberon/issues/693 -- consider merging into trigeminal ganglion, as this complicates the model subset: emapa_ehdaa2 synonym: "trigeminal preganglion" RELATED [EMAPA:16663] synonym: "trigeminal V preganglion" EXACT [EMAPA:16663] xref: EHDAA:924 xref: EMAPA:16663 xref: RETIRED_EHDAA2:0002089 is_a: UBERON:0003869 ! presumptive ganglion relationship: develops_from UBERON:0003070 ! trigeminal placode complex relationship: develops_from UBERON:0005563 ! trigeminal neural crest relationship: has_potential_to_develop_into UBERON:0001675 ! trigeminal ganglion relationship: transformation_of UBERON:0003070 {source="EHDAA2"} ! trigeminal placode complex [Term] id: UBERON:0006306 name: ulna cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a ulna." [OBOL:automatic] xref: EHDAA2:0002098 xref: EHDAA:7269 xref: EMAPA:18055 xref: VHOG:0001155 is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0010883 ! forelimb cartilage element is_a: UBERON:0015003 ! ulna endochondral element intersection_of: UBERON:0015003 ! ulna endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010847 ! ulna pre-cartilage condensation relationship: part_of UBERON:0003327 ! mesenchyme of forearm [Term] id: UBERON:0006311 name: chamber of eyeball namespace: uberon def: "A segment of the eyeball that is filled with refractive media." [http://orcid.org/0000-0002-6601-2165] synonym: "chamber of eye" RELATED [BTO:0002085] synonym: "eye chamber" EXACT [MA:0002459] synonym: "eyeball chamber" EXACT [FMA:58071] xref: BTO:0002085 xref: EMAPA:37529 {source="MA:th"} xref: FMA:58071 xref: MA:0002459 xref: NCIT:C32301 xref: SCTID:280540004 xref: UMLS:C0459556 {source="ncithesaurus:Chamber_of_the_Eye"} is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000063 ! organ subunit intersection_of: location_of UBERON:0006312 ! ocular refractive media intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: location_of UBERON:0006312 ! ocular refractive media relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0006312 name: ocular refractive media namespace: uberon def: "Body substance in a liquid or semi-solid state in the eyeball which serves to refract light." [http://orcid.org/0000-0002-6601-2165] xref: MA:0001911 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000463 ! organism substance relationship: part_of UBERON:0000019 ! camera-type eye property_value: UBPROP:0000009 "ocular refraction" xsd:string [Term] id: UBERON:0006314 name: bodily fluid namespace: uberon def: "Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not." [MESH:A12.207, Wikipedia:Body_fluid] subset: pheno_slim synonym: "body fluid" EXACT [GAID:266] synonym: "fluid" BROAD [] xref: BIRNLEX:20 xref: EMAPA:37441 {source="MA:th"} xref: FMA:280556 xref: GAID:266 xref: galen:BodyFluid xref: MESH:D001826 xref: Wikipedia:Body_fluid is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: has_quality PATO:0001548 ! quality of a liquid relationship: has_quality PATO:0001548 ! quality of a liquid [Term] id: UBERON:0006331 name: brainstem nucleus namespace: uberon def: "A nucleus of brain that is part of a brainstem." [OBOL:automatic] synonym: "brain stem nucleus" RELATED [EMAPA:32790] xref: EMAPA:32790 xref: MA:0000821 is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002298 ! brainstem relationship: part_of UBERON:0002298 ! brainstem [Term] id: UBERON:0006333 name: snout namespace: uberon subset: vertebrate_core synonym: "muzzle" NARROW [MA:0001910] xref: EMAPA:32806 xref: MA:0001910 xref: SCTID:41127006 xref: TAO:0001712 xref: Wikipedia:Snout xref: ZFA:0005496 is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0004089 ! midface property_value: RO:0002161 NCBITaxon:9606 property_value: UBPROP:0000001 "Surface structure that is the region of the head in front of and between the orbits, and above the lower jaw. Nares are located on the snout[ZFA]." xsd:string {date_retrieved="2012-10-05", ontology="ZFA", ontology_class="ZFA:0005496"} [Term] id: UBERON:0006347 name: communicating artery namespace: uberon def: "An artery that connects two larger arteries." [ncithesaurus:Communicating_Artery] comment: Grouping for anterior and posterior xref: EMAPA:18598 xref: MA:0001938 xref: NCIT:C52851 xref: UMLS:C1707451 {source="ncithesaurus:Communicating_Artery"} is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: connects UBERON:0001637 {cardinality="2"} ! artery relationship: connects UBERON:0001637 ! artery [Term] id: UBERON:0006355 name: superior vesical vein namespace: uberon subset: human_reference_atlas xref: EMAPA:18646 xref: MA:0002227 is_a: UBERON:0002460 {is_inferred="true", source="MA"} ! vesical vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0000056 ! ureter relationship: drains UBERON:0000056 ! ureter property_value: editor_note "inferred from artery" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0006428 name: basisphenoid bone namespace: uberon def: "Part of the base of the cranium between the basioccipital and the presphenoid, which usually ossifies separately in the embryo or in the young, and becomes a part of the sphenoid in the adult; in many animals it persists as a separate bone between the basioccipital bone and the presphenoidal bone." [ISBN:0-683-40008-8, MP:0000106] comment: "Endochondral ossification of the ventromedial portion of the braincase." [AAO:0000040] // "An endochondral bone that is located ventral to the pterosphenoid and dorsal to the parasphenoid. Basisphenoid is a median bone that is usually Y-shaped." [TAO:0000169] subset: pheno_slim synonym: "basisphenoid" EXACT [AAO:0000040] xref: AAO:0000040 xref: EMAPA:18706 xref: FMA:321630 xref: MA:0001463 xref: SCTID:95945003 xref: TAO:0000169 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0003462 ! facial bone is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0011164 {source="MA"} ! neurocranium bone relationship: contributes_to_morphology_of UBERON:0001677 ! sphenoid bone relationship: develops_from UBERON:0009194 {source="cjm"} ! basisphenoid cartilage condenstion relationship: part_of UBERON:0001677 ! sphenoid bone relationship: part_of UBERON:0002241 ! chondrocranium property_value: UBPROP:0000001 "An endochondral bone that is located ventral to the pterosphenoid and dorsal to the parasphenoid. Basisphenoid is a median bone that is usually Y-shaped.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000169", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "Endochondral ossification of the ventromedial portion of the braincase.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000040", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: part_of braincase and otic capsule skeleton (AAO:0000052)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000040", ontology="AAO"} [Term] id: UBERON:0006435 name: os penis namespace: uberon def: "The unique bone located in the glans penis of most mammals except humans; it is used for copulation and varies in size and shape by species." [MGI:anna, MP:0009103] subset: pheno_slim synonym: "baculum" EXACT [Wikipedia:Baculum] synonym: "os baculum" EXACT [] synonym: "penile bone" EXACT [MP:0009104, Wikipedia:Baculum] synonym: "penis bone" EXACT [Wikipedia:Baculum] xref: EMAPA:29769 xref: MA:0000406 xref: SCTID:27962002 xref: Wikipedia:Baculum is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0007719 ! bone of reproductive organ intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0000989 ! penis relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: part_of UBERON:0000989 ! penis property_value: RO:0002161 NCBITaxon:9606 property_value: UBPROP:0000008 "found in most mammals, with the exception of humans" xsd:string [Term] id: UBERON:0006440 name: os clitoris namespace: uberon def: "The ossified region of endochondral and membranous bone located in the clitoris of most mammals except humans; it is homologous to the penile bone (aka as baculum, penis bone or os penis) in male mammals." [MP:0011849] subset: pheno_slim synonym: "baubellum" EXACT [Wikipedia:Baculum] synonym: "clitoral bone" EXACT [MP:0011849] synonym: "clitoris bone" EXACT [] synonym: "os clitoridis" EXACT [Wikipedia:Baculum] xref: EMAPA:30823 xref: MA:0000387 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0007719 ! bone of reproductive organ intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0002411 ! clitoris relationship: contributes_to_morphology_of UBERON:0001434 ! skeletal system relationship: contributes_to_morphology_of UBERON:0002411 ! clitoris relationship: only_in_taxon NCBITaxon:40674 {source="Wikipedia"} ! Mammalia relationship: part_of UBERON:0002411 ! clitoris relationship: sexually_homologous_to UBERON:0006435 ! os penis property_value: RO:0002161 NCBITaxon:9606 [Term] id: UBERON:0006530 name: seminal fluid namespace: uberon def: "A substance formed from the secretion of one or more glands of the male genital tract in which sperm cells are suspended." [http://orcid.org/0000-0002-6601-2165] synonym: "male genital fluid" RELATED [] synonym: "male genital secretion" RELATED [] synonym: "milt" NARROW [PMID:31287811, PMID:35203131] {http://purl.obolibrary.org/obo/IAO_0000232="A secretion from the glands of the male reproductive system in some aquatic animals that contains sperm and is sprayed onto the eggs."} synonym: "seminal fluid" RELATED [BTO:0001232] synonym: "seminal plasma" EXACT [BTO:0001232] xref: BTO:0001232 xref: CALOHA:TS-0918 xref: EMAPA:36543 xref: FMA:62967 xref: MA:0002523 xref: MAT:0000057 xref: MIAA:0000057 is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006536 ! male reproductive gland secretion intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: part_of UBERON:0001968 ! semen intersection_of: produced_by UBERON:0005399 ! male reproductive gland relationship: capable_of_part_of GO:0048240 ! sperm capacitation relationship: capable_of_part_of GO:1902093 ! positive regulation of flagellated sperm motility relationship: part_of UBERON:0001968 ! semen property_value: IAO:0000232 "this ontology contains a number of subtypes of seminal fluid, defined according to glands (which are more taxonomically restricted)" xsd:string property_value: IAO:0000232 "we follow FMA and make this class a generic superclass of the secretions of different glands (prostate, bulbo-urethreal, seminal vesicle). MA (and ncit) follows a mixture model, where these secretions are part of the seminal fluid" xsd:string property_value: UBPROP:0000008 "This term covers a variety of species. Example: In D. melanogaster, seminal fluid proteins affect female receptivity, ovulation, oogenesis, sperm storage, sperm competition and mating plug formation" xsd:string {source="DOI:10.1046/j.1365-2540.2001.00961.x"} property_value: UBPROP:0000009 "seminal fluid may have a role in sperm capacitation, sperm motility" xsd:string [Term] id: UBERON:0006535 name: skin secretion namespace: uberon def: "A portion of organism substance that secreted_by a zone of skin." [OBOL:automatic] synonym: "skin fluid" RELATED [] synonym: "skin fluid/secretion" EXACT [MA:0002537] synonym: "skin substance" RELATED [] xref: MA:0002537 is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0000014 ! zone of skin relationship: produced_by UBERON:0000014 ! zone of skin [Term] id: UBERON:0006536 name: male reproductive gland secretion namespace: uberon def: "A portion of organism substance that is secreted by a male reproductive gland." [UBERON:cjm] synonym: "male reproductive system fluid" RELATED [] synonym: "male reproductive system fluid/secretion" EXACT [MA:0002521] synonym: "male reproductive system secretion" RELATED [] xref: EMAPA:36541 xref: MA:0002521 is_a: UBERON:0022293 ! reproductive gland secretion intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0005399 ! male reproductive gland relationship: produced_by UBERON:0005399 ! male reproductive gland [Term] id: UBERON:0006537 name: female reproductive gland secretion namespace: uberon def: "A portion of organism substance that is secreted by a female reproductive gland." [UBERON:cjm] synonym: "female reproductive system fluid" RELATED [] synonym: "female reproductive system fluid/secretion" EXACT [MA:0002510] synonym: "female reproductive system secretion" RELATED [] xref: MA:0002510 is_a: UBERON:0022293 ! reproductive gland secretion intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0005398 ! female reproductive gland relationship: produced_by UBERON:0005398 ! female reproductive gland [Term] id: UBERON:0006538 name: respiratory system fluid/secretion namespace: uberon def: "A portion of organism substance that secreted_by a respiratory system." [OBOL:automatic] synonym: "respiratory system fluid" RELATED [] synonym: "respiratory system secretion" RELATED [] xref: EMAPA:36550 xref: MA:0002533 xref: NCIT:C13722 xref: UMLS:C1514899 {source="ncithesaurus:Respiratory_System_Fluid_or_Secretion"} is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0001004 ! respiratory system relationship: produced_by UBERON:0001004 ! respiratory system [Term] id: UBERON:0006544 name: kidney vasculature namespace: uberon def: "A vasculature that is part of a kidney." [OBOL:automatic] subset: human_reference_atlas subset: vertebrate_core xref: EMAPA:28457 xref: TAO:0005305 xref: ZFA:0005305 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0006553 name: renal duct namespace: uberon def: "A tube in the kidney that collect and transport urine." [ZFIN:ZDB-PUB-071029-9] xref: TAO:0005289 xref: ZFA:0005289 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000058 ! duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney property_value: UBPROP:0000012 "in ZFA this is defined as part of mesonephros" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0006555 name: excretory tube namespace: uberon def: "A tube that is part of a excretory system." [OBOL:automatic] is_a: UBERON:0000025 ! tube intersection_of: UBERON:0000025 ! tube intersection_of: part_of UBERON:0001008 ! renal system relationship: part_of UBERON:0001008 ! renal system [Term] id: UBERON:0006562 name: pharynx namespace: uberon def: "The pharynx is the part of the digestive system immediately posterior to the mouth[GO]." [GO:0060465] subset: grouping_class subset: uberon_slim synonym: "anterior part of foregut" RELATED [] synonym: "pharyngeal tube" RELATED [] xref: FBbt:00005380 xref: MAT:0000049 xref: MESH:D010614 xref: MIAA:0000049 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: IAO:0000232 "currently this is an extremely generic class, encompassing both protostomes and deuterostomes." xsd:string property_value: IAO:0006012 "2023-04-20" xsd:string property_value: UBPROP:0000007 "branchial" xsd:string property_value: UBPROP:0000007 "pharyngeal" xsd:string [Term] id: UBERON:0006563 name: tunica media of pulmonary trunk namespace: uberon def: "Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA]." [FMA:85030, FMA:FMA] xref: FMA:85030 is_a: UBERON:0007239 ! tunica media of artery intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0002333 ! pulmonary trunk relationship: part_of UBERON:0002333 ! pulmonary trunk [Term] id: UBERON:0006565 name: female urethral meatus namespace: uberon def: "A urethral meatus that is part of a female urethra[Automatically generated definition]." [OBOL:automatic, Wikipedia:External_urethral_orifice_(female)] synonym: "distal urethral opening of female" RELATED [EMAPA:36453] synonym: "external orifice of female urethra" EXACT [FMA:85266] synonym: "external urethral orifice (female)" EXACT [FMA:85266] synonym: "female urethral meatus" EXACT [FMA:85266] synonym: "ostium urethrae externum (urethra feminina)" EXACT LATIN [FMA:85266, FMA:TA] synonym: "urethral meatus of clitoral urethra" EXACT [EMAPA:36453] synonym: "urethral opening of clitoral urethra" RELATED [EMAPA:36453] xref: EMAPA:36453 xref: FMA:85266 xref: MA:0002639 xref: SCTID:279479008 xref: Wikipedia:External_urethral_orifice_(female) is_a: UBERON:0012240 ! urethral meatus intersection_of: UBERON:0012240 ! urethral meatus intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0001334 ! female urethra property_value: UBPROP:0000001 "The external urethral orifice (urinary meatus) is the external opening of the urethra, from which urine is ejected during urination. It is placed about 2.5 cm behind the glans clitoridis and immediately in front of that of the vagina; it usually assumes the form of a short, sagittal cleft with slightly raised margins. To its left and right are the openings of the Skene's ducts." xsd:string {source="Wikipedia:External_urethral_orifice_(female)"} [Term] id: UBERON:0006566 name: left ventricle myocardium namespace: uberon def: "A myocardium that is part of a left ventricle of a heart." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "left ventricular myocardium" EXACT [FMA:9558] synonym: "myocardium of left ventricle" EXACT [FMA:9558] xref: EMAPA:17339 xref: FMA:9558 xref: MA:0002983 xref: SCTID:362021000 is_a: UBERON:0001083 ! myocardium of ventricle intersection_of: UBERON:0001083 ! myocardium of ventricle intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: continuous_with UBERON:0003618 ! aorta tunica media relationship: part_of UBERON:0002084 ! heart left ventricle property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Myocardium of ventricle which is continuous with the tunica media of aorta." xsd:string {source="FMA:9558"} [Term] id: UBERON:0006567 name: right ventricle myocardium namespace: uberon def: "A myocardium that is part of a right ventricle of a heart." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim synonym: "myocardium of right ventricle" EXACT [FMA:9535] synonym: "right ventricular myocardium" EXACT [FMA:9535] xref: EMAPA:17342 xref: FMA:9535 xref: MA:0002984 xref: SCTID:362020004 is_a: UBERON:0001083 ! myocardium of ventricle intersection_of: UBERON:0001083 ! myocardium of ventricle intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: continuous_with UBERON:0006563 ! tunica media of pulmonary trunk relationship: part_of UBERON:0002080 ! heart right ventricle property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Myocardium of ventricle which is continuous with the tunica media of the pulmonary trunk." xsd:string {source="FMA:9535"} [Term] id: UBERON:0006570 name: trabecula carnea of right ventricle namespace: uberon def: "A trabecula carnea that is part of a heart right ventricle." [OBOL:automatic] synonym: "trabeculae carneae (ventriculus dexter)" EXACT [FMA:7270] xref: FMA:7270 xref: SCTID:192373001 is_a: UBERON:0002511 ! trabecula carnea intersection_of: UBERON:0002511 ! trabecula carnea intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0002080 ! heart right ventricle [Term] id: UBERON:0006571 name: trabecula carnea of left ventricle namespace: uberon def: "A trabecula carnea that is part of a heart left ventricle." [OBOL:automatic] synonym: "trabeculae carneae (ventriculus sinister)" EXACT [FMA:7271] xref: FMA:7271 xref: SCTID:190344008 is_a: UBERON:0002511 ! trabecula carnea intersection_of: UBERON:0002511 ! trabecula carnea intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 ! heart left ventricle [Term] id: UBERON:0006574 name: pectinate line namespace: uberon def: "The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line:." [Wikipedia:Pectinate_line] synonym: "dentate line" RELATED [Wikipedia:Pectinate_line] synonym: "Hilton's 'white line'" RELATED [EMAPA:19159] synonym: "linea anocutanea" RELATED LATIN [Wikipedia:Pectinate_line] synonym: "linea pectinata canalis analis" EXACT LATIN [FMA:75383, FMA:TA] synonym: "pectinate line of anal canal" EXACT [FMA:75383] synonym: "recto-anal junction" RELATED [Wikipedia:Pectinate_line] synonym: "site of anal membrane" RELATED [EMAPA:19159] xref: EMAPA:19159 xref: FMA:75383 xref: NCIT:C34245 xref: SCTID:245445008 xref: UMLS:C0821671 {source="ncithesaurus:Pectinate_Line"} xref: Wikipedia:Pectinate_line is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:8410024 ! intestinal junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000931 ! proctodeum intersection_of: connects UBERON:0001046 ! hindgut relationship: connects UBERON:0000931 ! proctodeum relationship: connects UBERON:0001046 ! hindgut relationship: part_of UBERON:0000159 ! anal canal property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7b/Hemorrhoid.png" xsd:anyURI property_value: UBPROP:0000012 "FMA also has FMA:29321 but it's not clear how this differs" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0006595 name: presumptive endoderm namespace: uberon def: "Presumptive structure of the blastula that will develop into endoderm." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim xref: AAO:0000471 xref: EFO:0003437 xref: TAO:0000416 xref: ZFA:0000416 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0000307 ! blastula relationship: has_potential_to_develop_into UBERON:0000925 ! endoderm relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000307 ! blastula [Term] id: UBERON:0006596 name: presumptive blood namespace: uberon subset: efo_slim synonym: "future blood" EXACT [] xref: AAO:0000468 xref: EFO:0003439 xref: TAO:0000568 xref: ZFA:0000568 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0000178 ! blood relationship: has_potential_to_develop_into UBERON:0000178 ! blood [Term] id: UBERON:0006598 name: presumptive structure namespace: uberon def: "Portion of embryonic tissue determined by fate mapping to become a structure." [GOC:CVS, GOC:YMB, ZFA:0001116] synonym: "future structure" EXACT [] synonym: "presumptive structures" EXACT [ZFA:0001116] xref: AAO:0000479 xref: TAO:0001116 xref: ZFA:0001116 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: has_potential_to_develop_into UBERON:0000061 ! anatomical structure intersection_of: part_of UBERON:0000922 ! embryo relationship: has_potential_to_develop_into UBERON:0000061 ! anatomical structure property_value: editor_note "Consider merging with anlage" xsd:string [Term] id: UBERON:0006601 name: presumptive ectoderm namespace: uberon def: "Presumptive structure of the blastula that will develop into ectoderm." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "presumptive epidermis" RELATED [ZFA:0001376] xref: AAO:0000470 xref: EFO:0003466 xref: TAO:0001376 xref: XAO:0004132 xref: ZFA:0001376 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0000307 ! blastula relationship: has_potential_to_develop_into UBERON:0000924 ! ectoderm relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000307 ! blastula [Term] id: UBERON:0006603 name: presumptive mesoderm namespace: uberon def: "Presumptive structure of the blastula that will develop into mesoderm." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim xref: AAO:0000476 xref: EFO:0003467 xref: TAO:0001377 xref: ZFA:0001377 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0000926 ! mesoderm intersection_of: part_of UBERON:0000307 ! blastula relationship: has_potential_to_develop_into UBERON:0000926 ! mesoderm relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000307 ! blastula [Term] id: UBERON:0006606 name: mandibular symphysis namespace: uberon def: "A cartilaginous joint that connects left and right mandibles/dentary bones. Mandibular symphysis is unpaired[TAO,modified]." [TAO:wd, Wikipedia:Symphysis_menti, ZFA:0005488] subset: pheno_slim subset: vertebrate_core synonym: "dentary symphysis" EXACT [TAO:0001851] synonym: "inter-dentary joint" EXACT [TAO:0001851] synonym: "inter-mandibular joint" EXACT [TAO:0001851] synonym: "mental symphysis" RELATED [Wikipedia:Symphysis_menti] synonym: "symphysis mandibulae" RELATED LATIN [Wikipedia:Symphysis_menti] synonym: "symphysis menti" EXACT [MA:0001490] xref: AAO:0000277 xref: FMA:75779 xref: MA:0001490 xref: TAO:0001851 xref: Wikipedia:Symphysis_menti xref: ZFA:0005488 is_a: UBERON:0002216 {source="FMA"} ! symphysis intersection_of: UBERON:0002213 ! cartilaginous joint intersection_of: connects UBERON:0004742 {cardinality="2"} ! dentary relationship: connects UBERON:0004742 {notes="connects adjacent mandibles"} ! dentary relationship: part_of UBERON:0001710 ! lower jaw region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/64/Gray176.png" xsd:anyURI property_value: editor_note "this is placed as part of lower jaw region, as in this ontology the skeleton does not include joints" xsd:string property_value: UBPROP:0000001 "Joint that articulates the left and right dentary bones. Mandibular symphysis is unpaired.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001851", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000008 "in snakes, the mandibular symphysis is composed of soft tissues, allowing independent movement of each mandible" xsd:string {source="ISBN:0073040584"} [Term] id: UBERON:0006616 name: right external ear namespace: uberon def: "An external ear that is in the right side of a multicellular organism." [OBOL:automatic] subset: pheno_slim synonym: "right auricular region" BROAD [FMA:53643] xref: EMAPA:37361 {source="MA:th"} xref: FMA:53643 xref: SCTID:368567003 is_a: UBERON:0001691 ! external ear intersection_of: UBERON:0001691 ! external ear intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0006617 name: left external ear namespace: uberon def: "An external ear that is in the left side of a multicellular organism." [OBOL:automatic] subset: pheno_slim synonym: "left auricular region" BROAD [FMA:53644] xref: EMAPA:37360 {source="MA:th"} xref: FMA:53644 xref: SCTID:368589004 is_a: UBERON:0001691 ! external ear intersection_of: UBERON:0001691 ! external ear intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0006642 name: muscle layer of oviduct namespace: uberon def: "A muscle layer that is part of a fallopian tube." [OBOL:automatic] synonym: "muscle layer of fallopian tube" EXACT [FMA:18318] synonym: "muscle layer of oviduct" EXACT [FMA:18318] synonym: "muscle layer of uterine tube" EXACT [FMA:18318] synonym: "muscular coat of uterine tube" EXACT [FMA:18318] synonym: "muscular layer of uterine tube" EXACT [FMA:18318] synonym: "muscularis of uterine tube" EXACT [FMA:18318] synonym: "tunica muscularis (Tuba uterina)" EXACT [FMA:18318] synonym: "tunica muscularis tubae uterinae" EXACT LATIN [FMA:18318, FMA:TA] synonym: "uterine tubal muscularis" EXACT [FMA:18318] xref: EMAPA:29046 xref: FMA:18318 xref: SCTID:259488000 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0006660 ! muscular coat intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: part_of UBERON:0003889 ! fallopian tube [Term] id: UBERON:0006645 name: adventitia of epididymis namespace: uberon def: "An adventitia that is part of a epididymis." [OBOL:automatic] synonym: "epididymis adventitia" EXACT [FMA:19136] xref: EMAPA:30443 xref: FMA:19136 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005742 ! adventitia intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0001301 ! epididymis [Term] id: UBERON:0006646 name: muscle layer of epididymis namespace: uberon def: "A muscle layer that is part of a epididymis." [OBOL:automatic] xref: EMAPA:30747 xref: FMA:19149 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0006660 ! muscular coat intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0001301 ! epididymis [Term] id: UBERON:0006647 name: adventitia of ductus deferens namespace: uberon def: "An adventitia that is part of a vas deferens." [OBOL:automatic] synonym: "adventitia of deferent duct" EXACT [FMA:19238] synonym: "adventitia of ductus deferens" EXACT [FMA:19238] synonym: "adventitia of vas deferens" EXACT [FMA:19238] synonym: "deferent ductal adventitia" EXACT [FMA:19238] synonym: "tunica adventitia (ductus deferens)" EXACT [FMA:19238] synonym: "tunica adventitia ductus deferentis" EXACT LATIN [FMA:19238, FMA:TA] xref: EMAPA:29767 xref: FMA:19238 xref: SCTID:299803005 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005742 ! adventitia intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0001000 ! vas deferens relationship: part_of UBERON:0001000 ! vas deferens [Term] id: UBERON:0006648 name: adventitia of seminal vesicle namespace: uberon def: "An adventitia that is part of a seminal vesicle." [OBOL:automatic] synonym: "adventitia of seminal gland" EXACT [FMA:19403] synonym: "seminal vesicle adventitia" EXACT [FMA:19403] synonym: "tunica adventitia (vesicula seminalis)" EXACT [FMA:19403] synonym: "tunica adventitia glandulae vesiculosae" EXACT LATIN [FMA:19403, FMA:TA] xref: EMAPA:29775 xref: FMA:19403 xref: SCTID:252406002 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005742 ! adventitia intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0000998 ! seminal vesicle relationship: part_of UBERON:0000998 ! seminal vesicle [Term] id: UBERON:0006653 name: glans clitoris namespace: uberon def: "Erectile tissue at the end of the clitoris, which is continuous with the intermediate part of the vestibulovaginal bulbs[BTO]. The clitoral glans (glans clitoridis) is an external portion of the clitoris[WP]." [BTO:0003117, Wikipedia:Clitoral_glans] synonym: "clitoris glans" EXACT [FMA:19999] synonym: "glans clitoridis" RELATED [Wikipedia:Clitoral_glans] synonym: "glans clitoris" RELATED [Wikipedia:Clitoral_glans] synonym: "glans of clitoris" EXACT [FMA:19999] xref: BTO:0003117 xref: EMAPA:19170 xref: EMAPA:30829 xref: FMA:19999 xref: NCIT:C32681 xref: SCTID:362241002 xref: UMLS:C0227769 {source="ncithesaurus:Glans_Clitoris"} xref: Wikipedia:Clitoral_glans is_a: UBERON:0008324 ! erectile tissue is_a: UBERON:0035651 ! glans intersection_of: UBERON:0035651 ! glans intersection_of: part_of UBERON:0002411 ! clitoris relationship: develops_from UBERON:0013240 {source="cjm"} ! future glans clitoris relationship: part_of UBERON:0002411 ! clitoris property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8c/Clitoris_inner_anatomy.gif" xsd:anyURI [Term] id: UBERON:0006657 name: glenoid fossa namespace: uberon def: "Anatomical cavity for the proximal articular surface of the proximal limb or fin element with the scapulocoracoid or equivalent structure." [PHENOSCAPE:ad] subset: pheno_slim synonym: "cavitas glenoidalis" RELATED LATIN [Wikipedia:Glenoid_cavity] synonym: "cavitas glenoidalis scapulae" EXACT LATIN [FMA:23275, FMA:TA] synonym: "cavitus glenoidalis" EXACT [FMA:23275] synonym: "glenoid cavity" EXACT [FMA:23275] synonym: "glenoid cavity" RELATED [AAO:0000749] synonym: "glenoid cavity of scapula" EXACT [FMA:23275] synonym: "glenoid facet" EXACT [] xref: AAO:0000749 xref: EMAPA:25122 xref: FMA:23275 xref: NCIT:C32682 xref: SCTID:181914008 xref: UMLS:C1261046 {source="ncithesaurus:Glenoid_Fossa"} xref: Wikipedia:Glenoid_cavity is_a: UBERON:0004704 ! bone fossa relationship: adjacent_to UBERON:0006849 {notes="to be revised after scapulocoracoid fixes"} ! scapula relationship: part_of UBERON:0004753 ! scapulocoracoid property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ec/Gray328.png" xsd:anyURI property_value: UBPROP:0000001 "Cavity for the articulation of the forelimb formed by the scapula, coracoid, and clavicle.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000749", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: part_of scapular area (AAO:0000935)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000749", ontology="AAO"} property_value: UBPROP:0000008 "The glenoid fossa can be associated with the metapterygium in sarcopterygians, or either the meso- or propterygium in basal gnathostomes such as Chondrichthyans" xsd:string {source="ad"} property_value: UBPROP:0000012 "FMA also has classes for the bony parts around the cavity - these may be more useful than the cavity term itself" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0006658 name: interphalangeal joint namespace: uberon def: "A joint that connects one phalanx to another along a proximodistal axis." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "inter-phalangeal joint" EXACT [FMA:42765] synonym: "inter-phalanx joint" EXACT [] xref: EMAPA:37884 {source="MA:th"} xref: FMA:42765 xref: galen:InterphalangealJoint xref: NCIT:C101527 is_a: UBERON:0003841 ! autopod joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0003221 {cardinality="2"} ! phalanx relationship: connects UBERON:0003221 {notes="two phalanges in series"} ! phalanx relationship: part_of UBERON:0002544 {source="cjm"} ! digit property_value: UBPROP:0000001 "Hinge joints between the phalanges of the hand or foot[ncithesaurus:Interphalangeal_Joint]." xsd:string {source="ncithesaurus:Interphalangeal_Joint"} [Term] id: UBERON:0006660 name: muscular coat namespace: uberon def: "A region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis." [Wikipedia:Muscular_layer] synonym: "muscular coat" RELATED [Wikipedia:Muscularis_externa] synonym: "muscular layer" EXACT [OBOL:automatic] synonym: "muscularis" RELATED [] synonym: "muscularis externa" RELATED [BTO:0004838] synonym: "muscularis layer" EXACT [FMA:45634] synonym: "muscularis propria" RELATED [Wikipedia:Muscularis_externa] synonym: "transverse muscular fibers" RELATED [Wikipedia:Muscularis_externa] synonym: "tunica externa" RELATED [BTO:0004838] synonym: "tunica muscularis" EXACT LATIN [BTO:0004838] synonym: "tunica muscularis" RELATED [Wikipedia:Muscularis_externa] xref: BTO:0004838 xref: SCTID:86915006 xref: UMLS:C0225358 {source="ncithesaurus:Muscle_Layer"} xref: Wikipedia:Muscular_layer is_a: UBERON:0018260 ! layer of muscle tissue relationship: adjacent_to UBERON:0000009 ! submucosa relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: editor_note "currently this class conflates a generic layer of muscle and a specific layer found lining the digestive tract (the muscularis externa), typically composed of circular and longitudinal layers (although this varies)" xsd:string property_value: RO:0002171 UBERON:0000009 property_value: RO:0002171 UBERON:0006676 property_value: UBPROP:0000001 "An outer layer of smooth muscle surrounding a hollow or tubular organ as the bladder, esophagus, large intestine, small intestine, stomach, ureter, uterus, and vagina that often consists of an inner layer of circular fibers serving to narrow the lumen of the organ and an outer layer of longitudinal fibers serving to shorten its length[BTO]." xsd:string {source="BTO:0004838"} property_value: UBPROP:0000008 "typically smooth muscle, but there may be exceptions - in the upper esophagus, part of the externa is skeletal muscle, rather than smooth muscle." xsd:string [Term] id: UBERON:0006668 name: carotid canal namespace: uberon def: "On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]." [Wikipedia:Carotid_canal] synonym: "canalis caroticus" RELATED LATIN [Wikipedia:Carotid_canal] xref: EMAPA:18707 xref: FMA:55805 xref: Wikipedia:Carotid_canal is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: conduit_for UBERON:0001532 ! internal carotid artery relationship: conduit_for UBERON:0001532 ! internal carotid artery relationship: part_of UBERON:0001678 ! temporal bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4c/Gray141.png" xsd:anyURI [Term] id: UBERON:0006670 name: central tendon of diaphragm namespace: uberon def: "The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers." [MGI:csmith, MP:0012061] subset: pheno_slim synonym: "central tendon" EXACT [FMA:58279] synonym: "centrum tendineum" EXACT [FMA:58279] synonym: "centrum tendineum diaphragmatis" EXACT LATIN [FMA:58279, FMA:TA] xref: EMAPA:17702 xref: FMA:58279 xref: NCIT:C34119 xref: SCTID:244943002 xref: UMLS:C0230162 {source="ncithesaurus:Central_Tendon_of_the_Diaphragm"} xref: VHOG:0001399 xref: Wikipedia:Central_tendon_of_diaphragm is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000043 ! tendon is_a: UBERON:0003570 ! respiratory system connective tissue is_a: UBERON:0003837 ! thoracic segment connective tissue relationship: attaches_to UBERON:0002359 ! fibrous pericardium relationship: develops_from UBERON:0006239 ! future central tendon relationship: immediate_transformation_of UBERON:0006239 {evidence="definitional"} ! future central tendon relationship: part_of UBERON:0001103 {source="VHOG"} ! diaphragm property_value: UBPROP:0000003 "In mammals, the diaphragm muscle divides the thoracoabdominal cavity into thorax and abdomen. In most mammals, the diaphragm is a flat sheet with muscle fibers radiating outward from a central tendon, and the diaphragm's apposition to the cranial surface of the liver gives it a dome-shape. Muscle fiber contraction reduces the curvature of the dome, thereby expanding the thoracic cavity and aspirating air into the lungs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001399", ontology="VHOG", source="DOI:10.1016/j.resp.2006.06.003", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006675 name: venous valve namespace: uberon def: "A valve that is part of a vein." [OBOL:automatic] synonym: "valve of vein" EXACT [FMA:68095] xref: FMA:68095 xref: MESH:D055422 is_a: UBERON:0003978 ! valve is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003978 ! valve intersection_of: part_of UBERON:0001638 ! vein relationship: part_of UBERON:0001638 ! vein [Term] id: UBERON:0006677 name: surface of epithelium namespace: uberon def: "An anatomical boundary that adjacent_to a epithelium." [OBOL:automatic] synonym: "epithelium surface" EXACT [FMA:70997] xref: FMA:70997 is_a: UBERON:0036215 ! anatomical surface region intersection_of: UBERON:0036215 ! anatomical surface region intersection_of: bounding_layer_of UBERON:0000483 ! epithelium relationship: bounding_layer_of UBERON:0000483 ! epithelium relationship: part_of UBERON:0000483 ! epithelium [Term] id: UBERON:0006682 name: hypoglossal canal namespace: uberon def: "The hypoglossal canal is a bony canal in the occipital bone of the skull." [Wikipedia:Hypoglossal_canal] synonym: "anterior condylar canal" RELATED [EMAPA:19012] synonym: "canalis nervi hypoglossi" RELATED LATIN [Wikipedia:Hypoglossal_canal] synonym: "hyperglossal canal" RELATED [Wikipedia:Hypoglossal_canal] xref: EMAPA:19012 xref: FMA:75370 xref: SCTID:139380001 xref: Wikipedia:Hypoglossal_canal is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: conduit_for UBERON:0001650 ! hypoglossal nerve relationship: conduit_for UBERON:0001650 ! hypoglossal nerve relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of UBERON:0001676 ! occipital bone [Term] id: UBERON:0006686 name: spinal vein namespace: uberon def: "A vein that is part of a vertebral column." [OBOL:automatic] synonym: "spinal branch" RELATED [FMA:76735] synonym: "vena spinalis" EXACT LATIN [FMA:76735, FMA:TA] xref: EMAPA:18255 xref: FMA:76735 xref: MA:0002108 xref: SCTID:181376008 xref: Wikipedia:Spinal_veins is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001130 ! vertebral column [Term] id: UBERON:0006692 name: vertebral canal namespace: uberon def: "A conduit enclosed within the vertebral foramen of the vertebrae through which the spinal cord passes." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Spinal_canal] subset: pheno_slim synonym: "c. vertebralis" RELATED LATIN [Wikipedia:Spinal_canal] synonym: "foramen vertebrale" RELATED [AAO:0000693] synonym: "neural canal" RELATED [AAO:0000693] synonym: "spinal canal" RELATED [AAO:0000693] synonym: "spinal cavity" RELATED [Wikipedia:Spinal_canal] synonym: "vertebral canal" RELATED [Wikipedia:Spinal_canal] xref: AAO:0000693 xref: FMA:9680 xref: GAID:242 xref: NCIT:C33869 xref: NCIT:C34221 xref: SCTID:361746009 xref: UMLS:C0037922 {source="ncithesaurus:Vertebral_Canal"} xref: UMLS:C1522467 {source="ncithesaurus:Neural_Canal"} xref: Wikipedia:Spinal_canal is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004111 ! anatomical conduit intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: conduit_for UBERON:0002240 ! spinal cord intersection_of: lumen_of UBERON:0001130 ! vertebral column relationship: conduit_for UBERON:0002240 ! spinal cord relationship: lumen_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001130 ! vertebral column relationship: surrounds UBERON:0002240 ! spinal cord property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray82.png" xsd:anyURI property_value: editor_note "TODO - check neural vs vertebral canal; embryonic vs adult?" xsd:string property_value: UBPROP:0000001 "Canal formed by the vertebral centra ventrally, the pedicels laterally, and the neural arches dorsally that encloses and protects the spinal cord.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000693", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0006715 name: radio-ulna namespace: uberon def: "Paired, long bones of endochondral origin formed by the fusion of the radius and ulna." [AAO:Maglia_et_al_2007] synonym: "radioulna" EXACT [XAO:0003209] synonym: "radius+ulna" EXACT [] synonym: "radius-ulna" EXACT [XAO:0003209] xref: AAO:0000901 xref: XAO:0003209 is_a: UBERON:0003466 ! forelimb zeugopod bone is_a: UBERON:0015002 ! radius-ulna endochondral element intersection_of: UBERON:0015002 ! radius-ulna endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: derived_from_ancestral_fusion_of UBERON:0001423 ! radius bone relationship: derived_from_ancestral_fusion_of UBERON:0001424 ! ulna relationship: develops_from UBERON:0010848 ! radius-ulna cartilage element [Term] id: UBERON:0006716 name: mesopodium region namespace: uberon def: "The third segment of the limb, including either the wrist segment (carpus) or the ankle segment (tarsus)." [https://orcid.org/0000-0002-6601-2165, MA:th, Wikipedia:Carpus_and_tarsus_of_land_vertebrates] synonym: "carpus/tarsus" EXACT [] synonym: "mesopod" RELATED [] synonym: "mesopodial limb segment" EXACT [MA:th] synonym: "mesopodial segment" EXACT [] xref: Wikipedia:Carpus_and_tarsus_of_land_vertebrates is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 ! limb segment intersection_of: distally_connected_to UBERON:0009877 ! metapodium region intersection_of: proximally_connected_to UBERON:0002471 ! zeugopod relationship: distally_connected_to UBERON:0009877 ! metapodium region relationship: has_skeleton UBERON:0009878 ! mesopodial skeleton relationship: part_of UBERON:0002470 {source="MA:th"} ! autopod region relationship: proximally_connected_to UBERON:0002471 ! zeugopod property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group" xsd:string [Term] id: UBERON:0006717 name: autopodial skeleton namespace: uberon def: "The collection of all skeletal elements in an autopodium region." [https://orcid.org/0000-0002-6601-2165] synonym: "autopod skeleton" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "autopodial skeleton" EXACT [VSAO:0005019] synonym: "autopodium" RELATED [VSAO:0005019, VSAO:NI] synonym: "skeletal parts of autopod" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "skeleton of autopod" EXACT [https://orcid.org/0000-0002-6601-2165] xref: VSAO:0005019 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002470 ! autopod region relationship: part_of UBERON:0002470 ! autopod region relationship: part_of UBERON:0004381 ! skeleton of limb relationship: proximally_connected_to UBERON:0011584 ! zeugopodial skeleton relationship: skeleton_of UBERON:0002470 ! autopod region property_value: UBPROP:0000001 "Distal section of the limb skeleton, consisting of the anterior autopodium or posterior autopodium.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0005019", ontology="VSAO", source="VSAO:NI"} property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group" xsd:string [Term] id: UBERON:0006756 name: median lingual swelling namespace: uberon def: "During the third week of embryological development there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings which rise from the inner surface of the mandibular arch and meet in the middle line. The site of their meeting remains post-embryonically as the median sulcus of the tongue. The tuberculum impar is said to form the central part of the tongue immediately in front of the foramen cecum, but Hammar insists that it is purely a transitory structure and forms no part of the adult tongue[WP, Gray's]." [Wikipedia:Tuberculum_impar] comment: The thyroid initially develops caudal to the tuberculum impar . This embryonic swelling arises from the first pharyngeal arch and occurs midline on the floor of the developing pharynx, eventually helping form the tongue as the 2 lateral lingual swellings overgrow it. [http://emedicine.medscape.com/article/845125-overview] synonym: "median lingual swelling" EXACT [EHDAA2:0001081] synonym: "median tongue bud" EXACT [http://emedicine.medscape.com/article/845125-overview] synonym: "tuberculum impar" EXACT [] synonym: "tuberculum linguale mediale" EXACT [Wikipedia:Tuberculum_impar] xref: EHDAA2:0001081 xref: EMAPA:17187 xref: FMA:312476 xref: SCTID:308821003 xref: VHOG:0000730 xref: Wikipedia:Tuberculum_impar is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 relationship: part_of UBERON:0006260 {source="EHDAA2"} ! lingual swellings property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray979.png" xsd:anyURI property_value: UBPROP:0000003 "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000730", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x", source="http://bgee.unil.ch/"} [Term] id: UBERON:0006757 name: lateral lingual swelling namespace: uberon def: "During the third week there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings (or distal tongue bud) which rise from the inner surface of the mandibular arch and meet in the middle line." [Wikipedia:Lateral_lingual_swelling] synonym: "lateral lingual prominence" RELATED [] synonym: "lateral swellings" RELATED [Wikipedia:Lateral_lingual_swelling] synonym: "tuberculum laterale" RELATED [Wikipedia:Lateral_lingual_swelling] synonym: "tuberculum linguale laterale" RELATED LATIN [Wikipedia:Lateral_lingual_swelling] xref: EHDAA2:0000911 xref: EMAPA:17189 xref: FMA:313628 xref: VHOG:0000731 xref: Wikipedia:Lateral_lingual_swelling is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 relationship: part_of UBERON:0006260 ! lingual swellings property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5c/Gray979.png" xsd:anyURI property_value: UBPROP:0000003 "Most adult amphibians have a tongue, as do all known reptiles, birds and mammals. Thus it is likely that the tongue appeared with the establishment of tetrapods and this structure seems to be related, to some extant, to the terrestrial lifestyle.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000731", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2002.00073.x Iwasaki S, Evolution of the structure and function of the vertebrate tongue. J Anat (2002)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000010 "paired" xsd:string [Term] id: UBERON:0006761 name: corneo-scleral junction namespace: uberon def: "The edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm." [MP:0013477] comment: This location has parts such as blood vessels etc. See PMC2868485, http://www.ncbi.nlm.nih.gov/pubmed/2695343 subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "cornea limbus" EXACT [] synonym: "corneal limbus" EXACT [FMA:58342, GAID:896] synonym: "corneal-scleral limbus" EXACT [PMID:17051547] synonym: "corneoscleral junction" EXACT [GAID:896] synonym: "limbus corneae" EXACT LATIN [Wikipedia:Corneal_limbus] synonym: "limbus corneae" RELATED LATIN [Wikipedia:Corneal_limbus] synonym: "sclerocorneal junction" EXACT [FMA:58342] synonym: "sclerocorneal limbus" EXACT [GAID:896] xref: EFO:0001403 xref: EMAPA:37835 {source="MA:th"} xref: FMA:58342 xref: GAID:896 xref: MESH:D016850 xref: SCTID:63716004 xref: Wikipedia:Corneal_limbus xref: ZFA:0005570 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000964 ! cornea intersection_of: connects UBERON:0001773 ! sclera relationship: connects UBERON:0000964 ! cornea relationship: connects UBERON:0001773 ! sclera relationship: part_of UBERON:0000019 ! camera-type eye property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3d/Limbus.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0006767 name: head of femur namespace: uberon def: "The hemispheric articular surface at the upper extremity of the thigh bone[Stedman, 26th ed]. The femur head is the highest part of the thigh bone. It is supported by the neck of the femur. The head is globular and forms rather more than a hemisphere, is directed upward, medialward, and a little forward, the greater part of its convexity being above and in front. Its surface is smooth, coated with cartilage in the fresh state, except over an ovoid depression, the fovea capitis femoris, which is situated a little below and behind the center of the head, and gives attachment to the ligament of head of femur. If there is a fracture of the neck of the femur, the blood supply through the ligament becomes crucial. In orthopedic surgery, the head of the femur is important because it can undergo avascular necrosis and consequent osteochondritis dissecans. The head is removed in total hip replacement surgery [WP]." [MESH:A02.835.232.500.247.343, Wikipedia:Femur_head] subset: human_reference_atlas subset: pheno_slim synonym: "acetabular head" EXACT [AAO:0000892] synonym: "capital femoral epiphysis" RELATED [http://medical-dictionary.thefreedictionary.com/capital+femoral+epiphysis] synonym: "caput femoris" RELATED LATIN [AAO:0000892, Wikipedia:Femur_head] synonym: "femoral head" EXACT [FMA:32851] synonym: "femur head" RELATED [MESH:A02.835.232.500.247.343] synonym: "kopf des Schenkelbeins" EXACT LATIN [FMA:32851, FMA:TA] xref: AAO:0000892 xref: EMAPA:37541 {source="MA:th"} xref: FMA:32851 xref: galen:FemoralHead xref: MA:0003050 xref: MESH:D005270 xref: NCIT:C32718 xref: SCTID:361791000 xref: UMLS:C0015813 {source="ncithesaurus:Head_of_the_Femur"} xref: Wikipedia:Femur_head is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: adjacent_to UBERON:0001269 ! acetabular part of hip bone relationship: part_of UBERON:0004412 ! proximal epiphysis of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray243.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Proximal head of the femur, which articulates with the acetabulum.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000892", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0006799 name: glandular epithelium namespace: uberon def: "An epithelium that is composed primarily of secretory cells." [http://orcid.org/0000-0002-6601-2165] xref: BTO:0002991 xref: NCIT:C43370 xref: NCIT:C45715 xref: UMLS:C0682578 {source="ncithesaurus:Glandular_Epithelium"} xref: UMLS:C1708242 {source="ncithesaurus:Glandular_Epithelial_Tissue"} is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell relationship: composed_primarily_of CL:0000150 ! glandular epithelial cell property_value: editor_note "consider splitting epithelium from epithelial tissue" xsd:string [Term] id: UBERON:0006801 name: proximal head of humerus namespace: uberon alt_id: UBERON:3000835 def: "Hemispherical structure on proximal epiphysis of humerus that articulates with glenoid cavity[WP,modified]." [Wikipedia:Upper_extremity_of_humerus#Humeral_head] subset: pheno_slim synonym: "caput humeri" RELATED [AAO:0000835, Wikipedia:Upper_extremity_of_humerus#Humeral_head] synonym: "head of humerus" EXACT [FMA:13304] synonym: "humeral head" RELATED [FMA:13304, PHENOSCAPE:curators] xref: AAO:0000835 xref: EMAPA:25050 xref: FMA:13304 xref: galen:HeadOfHumerus xref: NCIT:C32720 xref: SCTID:181924000 xref: UMLS:C0223683 {source="ncithesaurus:Head_of_the_Humerus"} xref: Wikipedia:Upper_extremity_of_humerus#Humeral_head is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: connected_to UBERON:0006657 ! glenoid fossa relationship: overlaps UBERON:0001470 ! glenohumeral joint relationship: part_of UBERON:0004411 ! proximal epiphysis of humerus property_value: UBPROP:0000001 "Hemispherical ball on the proximal end of the humerus that fits into the glenoid cavity of the pectoral girdle to form the shoulder joint[AAO]." xsd:string {external_class="AAO:0000835", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0006802 name: acetabular rim namespace: uberon def: "A prominent unever rim that bounds the acetabulum, serving as the attachment for the acetabular labrum, which reduces its opening, and deepens the surface for formation of the hip joint." [Wikipedia:Acetabulum#Structure] synonym: "acetabular margin" RELATED [] xref: FMA:16941 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0001269 ! acetabular part of hip bone [Term] id: UBERON:0006803 name: obturator foramen namespace: uberon def: "The obturator foramen is the hole created by the ischium and pubis bones of the pelvis through which nerves and muscles pass." [Wikipedia:Obturator_foramen] synonym: "foramen obturatorium" EXACT LATIN [FMA:16999] synonym: "foramen obturatum" RELATED LATIN [Wikipedia:Obturator_foramen] xref: AAO:0000863 xref: FMA:16999 xref: NCIT:C75332 xref: SCTID:361777006 xref: UMLS:C0223670 {source="ncithesaurus:Obturator_Foramen"} xref: Wikipedia:Obturator_foramen is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004120 ! mesoderm-derived structure relationship: conduit_for UBERON:0001314 ! obturator artery relationship: conduit_for UBERON:0005465 ! obturator nerve relationship: part_of UBERON:0007832 {source="AAO"} ! pelvic girdle skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/ff/Skeletpelvis-pubis.jpg" xsd:anyURI property_value: UBPROP:0000001 "Small opening for the passage of the obturatorius nerve that perforates the pubis.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000863", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: subclass pelvic girdle opening (AAO:0000767)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000863", ontology="AAO"} [Term] id: UBERON:0006810 name: olecranon namespace: uberon def: "The olecranon is a large, thick, curved bony eminence of the forearm that projects behind the elbow. It is situated at the upper (proximal) end of the ulna, one of the two bones in the forearm. When the hand faces forward the olecranon faces towards the back (posteriorly). It is bent forward at the summit so as to present a prominent lip which is received into the olecranon fossa of the humerus in extension of the forearm. Its base is contracted where it joins the body and the narrowest part of the upper end of the ulna. Its posterior surface, directed backward, is triangular, smooth, subcutaneous, and covered by a bursa. Its superior surface is of quadrilateral form, marked behind by a rough impression for the insertion of the Triceps brachii; and in front, near the margin, by a slight transverse groove for the attachment of part of the posterior ligament of the elbow-joint. Its anterior surface is smooth, concave, and forms the upper part of the semilunar notch. Its borders present continuations of the groove on the margin of the superior surface; they serve for the attachment of ligaments, viz. , the back part of the ulnar collateral ligament medially, and the posterior ligament laterally. From the medial border a part of the Flexor carpi ulnaris arises; while to the lateral border the anconeus muscle is attached." [Wikipedia:Olecranon] subset: pheno_slim synonym: "olecranon process" RELATED [Wikipedia:Olecranon] synonym: "olecranon process of ulna" EXACT [Wikipedia:Olecranon] synonym: "ulnar process" RELATED [AAO:0000843] xref: AAO:0000843 xref: FMA:39795 xref: NCIT:C33200 xref: SCTID:181949001 xref: UMLS:C0223710 {source="ncithesaurus:Olecranon"} xref: Wikipedia:Olecranon is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: part_of UBERON:0006822 ! proximal epiphysis of ulna property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/60/Gray212.png" xsd:anyURI property_value: editor_note "check AAO" xsd:string property_value: UBPROP:0000001 "Large and thick process situated at the proximal (upper) end of the ulna. Its inner face forms the medial articular surface that articulates with the humeral head.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000843", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0006813 name: nasal skeleton namespace: uberon def: "Structural framework that provides support to the nasal sacs and ducts." [AAO:0000320] subset: pheno_slim synonym: "skeleton of nose" EXACT [FMA:60116] xref: AAO:0000320 xref: FMA:60116 xref: SCTID:281486007 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0000004 ! nose relationship: part_of UBERON:0000004 {source="FMA"} ! nose relationship: part_of UBERON:0003113 {notes="facial series", source="Kardong-abduced"} ! dermatocranium relationship: part_of UBERON:0011156 ! facial skeleton relationship: skeleton_of UBERON:0000004 ! nose [Term] id: UBERON:0006815 name: areolar connective tissue namespace: uberon def: "Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand." [FMA:63897] synonym: "areolar tissue" RELATED [] synonym: "loose areolar connective tissue" EXACT [FMA:63897] synonym: "loose connective tissue" RELATED [AAO:0000027] xref: AAO:0000027 xref: FMA:63897 xref: SCTID:68477002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011825 {source="FMA"} ! loose connective tissue relationship: has_part CL:1000303 {source="FMA"} ! fibroblast of areolar connective tissue relationship: part_of UBERON:0000030 ! lamina propria relationship: protects UBERON:0000062 ! organ property_value: UBPROP:0000001 "Also known as loose connective tissue. A pliable, mesh-like tissue with a fluid matrix that functions to cushion and protect body organs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000027", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: subclass connective tissue proper (AAO:0000099)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000027", ontology="AAO"} property_value: UBPROP:0000009 "cushions body organs" xsd:string {source="AAO"} [Term] id: UBERON:0006822 name: proximal epiphysis of ulna namespace: uberon def: "The head of ulna presents an articular surface, part of which, of an oval or semilunar form, is directed downward, and articulates with the upper surface of the triangular articular disk which separates it from the wrist-joint; the remaining portion, directed lateralward, is narrow, convex, and received into the ulnar notch of the radius." [Wikipedia:Head_of_ulna] subset: pheno_slim synonym: "caput ulnae" EXACT LATIN [FMA:33751, FMA:TA] synonym: "caput ulnae" RELATED LATIN [Wikipedia:Head_of_ulna] synonym: "head of ulna" EXACT [FMA:33751] synonym: "proximal end of ulna" EXACT [FMA:33751] synonym: "upper end of ulna" EXACT [FMA:33751] xref: FMA:33751 xref: galen:HeadOfUlna xref: SCTID:304590006 xref: Wikipedia:Head_of_ulna is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004386 ! epiphysis of ulna intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001424 ! ulna [Term] id: UBERON:0006828 name: trabecula carnea of atrium namespace: uberon def: "The supporting bundles of muscular fibers lining the walls of the atria[MP]." [MP:0010581] is_a: UBERON:0002511 ! trabecula carnea intersection_of: UBERON:0002511 ! trabecula carnea intersection_of: part_of UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0002081 ! cardiac atrium property_value: editor_note "Not present in any AO. Note that WP states that trabecular carnea are ventricular and 'They should not be confused with the pectinate muscles, which are present in the right and left atria only'" xsd:string [Term] id: UBERON:0006833 name: lumen of trachea namespace: uberon def: "An anatomical space that surrounded_by a trachea." [OBOL:automatic] synonym: "lumen of cartilaginous trachea" EXACT [OBOL:automatic] synonym: "tracheal lumen" EXACT [FMA:7469] xref: FMA:7469 xref: SCTID:197486000 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0003126 ! trachea relationship: luminal_space_of UBERON:0003126 ! trachea relationship: part_of UBERON:0003126 ! trachea [Term] id: UBERON:0006834 name: uterus or analog namespace: uberon def: "A subdivision of a the reproductive tract in a female organism that is the site of embryo development." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "uterus" BROAD SENSU [FBbt:00004924] xref: TADS:0000421 xref: WBbt:0006760 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: site_of GO:0009790 ! embryo development relationship: only_in_taxon NCBITaxon:33208 ! Metazoa relationship: part_of UBERON:0000474 ! female reproductive system relationship: site_of GO:0009790 ! embryo development [Term] id: UBERON:0006841 name: central vein of liver namespace: uberon def: "Vein that is central to a lobule in the liver." [ZFA:0005168] subset: human_reference_atlas subset: vertebrate_core synonym: "central vein" BROAD [ZFA:0005168] synonym: "terminal branch of hepatic vein" EXACT [FMA:17544] synonym: "terminal hepatic venule" EXACT [FMA:17544] synonym: "vena centralis (hepar)" EXACT [FMA:17544] xref: FMA:17544 xref: NCIT:C32281 xref: SCTID:272023004 xref: TAO:0005168 xref: Wikipedia:Central_veins_of_liver xref: ZFA:0005168 is_a: UBERON:0013126 ! vein of abdomen is_a: UBERON:0015796 ! liver blood vessel relationship: part_of UBERON:0004647 ! liver lobule property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0006844 name: cusp of tooth namespace: uberon def: "A raised area of the biting surface of a tooth." [ncithesaurus:Tooth_Cusp] subset: vertebrate_core synonym: "cusp" BROAD [] synonym: "tooth cone" RELATED [ISBN:0073040584] synonym: "tooth cusp" EXACT [FMA:56481] xref: FMA:56481 xref: NCIT:C94568 xref: SCTID:362107000 xref: TAO:0001973 xref: UMLS:C0226994 {source="ncithesaurus:Tooth_Cusp"} xref: ZFA:0005434 is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: part_of UBERON:0003675 {source="FMA"} ! tooth crown property_value: IAO:0000232 "this class may be obsoleted and split - the TAO class is generic, the mammalian class refers specifically to a molariform tooth" xsd:string property_value: UBPROP:0000001 "Anatomical structure that is a natural outgrowth, prominence, or point that is part of the surface of a tooth.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001973", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "the elevated, somewhat pointed portions of the chewing surfaces on premolar and molar teeth" xsd:string {date_retrieved="2012-09-28", source="http://anthro.palomar.edu/primate/glossary.htm"} [Term] id: UBERON:0006846 name: surface groove namespace: uberon def: "A furrow or an incomplete tube." [AEO:0000161, AEO:JB, https://github.com/obophenotype/human-developmental-anatomy-ontology/issues/4] comment: Surface groove is modelled as immaterial - see https://github.com/obophenotype/uberon/issues/2667 for discussion subset: grouping_class synonym: "groove" RELATED [AEO:0000161] xref: AEO:0000161 xref: EHDAA2_RETIRED:0003161 is_a: UBERON:0000466 ! immaterial anatomical entity relationship: has_quality PATO:0002255 ! grooved property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2667" xsd:string [Term] id: UBERON:0006849 name: scapula namespace: uberon alt_id: UBERON:0001124 alt_id: UBERON:0010904 def: "Endochondral bone that is dorsoventrally compressed and provides attachment site for muscles of the pectoral appendage." [https://github.com/obophenotype/uberon/issues/204, https://github.com/obophenotype/uberon/issues/339, VSAO:0000157] subset: efo_slim subset: human_reference_atlas subset: pheno_slim subset: uberon_slim synonym: "scapula bone" RELATED [BTO:0001218] synonym: "scapulae" EXACT PLURAL [ZFA:0000583] synonym: "scapulas" RELATED PLURAL [TAO:0000583] synonym: "shoulder blade" NARROW [] xref: AAO:0000751 xref: BTO:0001218 xref: CALOHA:TS-0897 xref: EFO:0001400 xref: EMAPA:18722 xref: FMA:13394 xref: GAID:186 xref: galen:Scapula xref: MA:0001330 xref: MESH:D012540 xref: NCIT:C12783 xref: SCTID:302517007 xref: TAO:0000583 xref: UMLS:C0036277 {source="ncithesaurus:Scapula"} xref: VHOG:0001398 xref: VSAO:0000157 xref: Wikipedia:Scapula xref: ZFA:0000583 is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0007829 ! pectoral girdle bone is_a: UBERON:0015057 ! scapula endochondral element intersection_of: UBERON:0015057 ! scapula endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0004753 {source="ZFA"} ! scapulocoracoid relationship: develops_from UBERON:0006290 {evidence="definitional"} ! scapula cartilage element relationship: distally_connected_to UBERON:0000976 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! humerus relationship: distally_connected_to UBERON:0007272 ! pectoral appendage skeleton relationship: overlaps UBERON:0001470 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! glenohumeral joint relationship: overlaps UBERON:0003692 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! acromioclavicular joint relationship: part_of UBERON:0001467 {gci_relation="part_of", gci_filler="NCBITaxon:32523", source="FMA"} ! shoulder property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/59/Pectoral_girdles-en.svg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Endochondral bone that is located medial to the cleithrum, and articulates ventrally with the coracoid, medially with the mesocoracoid when the later is present and posteriorly with the upper one to three proximal radials. The scapula develops from the scapulocoracoid cartilage and belongs to the primary pectoral girdle. It may be perforated by the scapular foramen or it may be notched ventr and forms together with a similar notch of the coracoid the scapulocoracoid foramen[TAO:0000583]." xsd:string {source="TAO:0000583"} property_value: UBPROP:0000001 "Paired bony elements of endochondral origin. They are situated at the level of the jaw articulation, in a vertical position, with the suprascapular margin being dorsal and the glenoid end being ventral.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000751", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: has pars glenoidalis of scapula (AAO:0000753)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000751", ontology="AAO"} property_value: UBPROP:0000002 "relationship loss: part_of scapular area (AAO:0000935)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000751", ontology="AAO"} property_value: UBPROP:0000007 "scapular" xsd:string property_value: UBPROP:0000008 "present in all tetrapods with even vestiges of anterior limbs, e.g., turtles & birds & mammals." xsd:string {source="ISBN:978-0-12-319060-4"} property_value: UBPROP:0000011 "chick scapula is of dual origin and segmentally organized" xsd:string [Term] id: UBERON:0006855 name: muscular coat of ureter namespace: uberon def: "A muscular coat that is part of a ureter." [OBOL:automatic] synonym: "muscular coat of ureter" EXACT [FMA:15893] synonym: "muscular layer of ureter" EXACT [FMA:15893] synonym: "muscularis of ureter" EXACT [FMA:15893] synonym: "tunica muscularis (ureter)" EXACT LATIN [FMA:TA] synonym: "tunica muscularis ureteris" EXACT LATIN [FMA:TA] synonym: "ureteral smooth muscle layer" RELATED [EMAPA:28567] xref: EMAPA:28811 xref: FMA:15893 xref: MA:0002654 xref: SCTID:3563003 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0006660 ! muscular coat intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0000056 ! ureter relationship: part_of UBERON:0009916 {source="FMA"} ! wall of ureter [Term] id: UBERON:0006861 name: diaphysis proper namespace: uberon def: "Subdivision of long bone which forms the part of the bone between two metaphyses. Note that the diaphysis includes the metaphyses, but the diaphysis proper excludes these." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "body proper of long bone" EXACT [FMA:32688] synonym: "long bone diaphysis" RELATED INCONSISTENT [MA:0002803] synonym: "shaft proper of long bone" EXACT [FMA:32688] xref: FMA:32688 xref: MA:0002803 is_a: UBERON:0005055 ! zone of long bone relationship: contributes_to_morphology_of UBERON:0002495 ! long bone relationship: part_of UBERON:0004769 ! diaphysis property_value: RO:0002171 UBERON:0001438 property_value: UBPROP:0000012 "The MA class is associated with EMAPA:35505 but we associate this with the more precise concept of diaphyseal plate" xsd:string {external_ontology="MA"} [Term] id: UBERON:0006862 name: diaphysis of femur namespace: uberon def: "A diaphysis that is part of a femur[Automatically generated definition]." [OBOL:automatic, Wikipedia:Body_of_femur] subset: pheno_slim synonym: "body of femur" EXACT [FMA:32847] synonym: "corpus femoris" EXACT LATIN [FMA:32847, FMA:TA] synonym: "femoral diaphysis" EXACT [FMA:32847] synonym: "femoral shaft" EXACT [] synonym: "shaft of femur" EXACT [FMA:32847] xref: EMAPA:37538 {source="MA:th"} xref: FMA:32847 xref: MA:0003055 xref: NCIT:C96209 xref: SCTID:182048009 xref: Wikipedia:Body_of_femur is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0000981 ! femur relationship: part_of UBERON:0000981 ! femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2b/Gray244.png" xsd:anyURI property_value: UBPROP:0000001 "The body of the femur (or shaft), almost cylindrical in form, is a little broader above than in the center, broadest and somewhat flattened from before backward below. It is slightly arched, so as to be convex in front, and concave behind, where it is strengthened by a prominent longitudinal ridge, the linea aspera. It presents for examination three borders, separating three surfaces. Of the borders, one, the linea aspera, is posterior, one is medial, and the other, lateral[Wikipedia:Body_of_femur]." xsd:string {source="Wikipedia:Body_of_femur"} [Term] id: UBERON:0006863 name: proximal metaphysis of femur namespace: uberon def: "A proximal metaphysis that is part of a femur." [OBOL:automatic] subset: pheno_slim xref: FMA:32878 is_a: UBERON:0004378 ! proximal metaphysis is_a: UBERON:0006865 ! metaphysis of femur intersection_of: UBERON:0004378 ! proximal metaphysis intersection_of: part_of UBERON:0000981 ! femur [Term] id: UBERON:0006864 name: distal metaphysis of femur namespace: uberon def: "A distal metaphysis that is part of a femur." [OBOL:automatic] subset: pheno_slim xref: FMA:32881 is_a: UBERON:0004377 ! distal metaphysis is_a: UBERON:0006865 ! metaphysis of femur intersection_of: UBERON:0004377 ! distal metaphysis intersection_of: part_of UBERON:0000981 ! femur [Term] id: UBERON:0006865 name: metaphysis of femur namespace: uberon def: "A metaphysis that is part of a femur." [OBOL:automatic] subset: pheno_slim synonym: "femoral metaphysis" EXACT [FMA:32875] xref: EMAPA:37540 {source="MA:th"} xref: FMA:32875 xref: MA:0003052 is_a: UBERON:0001438 ! metaphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001438 ! metaphysis intersection_of: part_of UBERON:0000981 ! femur relationship: part_of UBERON:0006862 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! diaphysis of femur [Term] id: UBERON:0006866 name: terminal part of digestive tract namespace: uberon def: "The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus." [http://orcid.org/0000-0002-6601-2165] synonym: "rectal part of digestive tract" RELATED [] synonym: "rectum" NARROW [FBbt:00005756] synonym: "terminal section of digestive tract" RELATED [] xref: FBbt:00005756 xref: WBbt:0005773 is_a: UBERON:0004921 ! subdivision of digestive tract relationship: continuous_with UBERON:0001245 ! anus relationship: develops_from UBERON:0001046 ! hindgut property_value: IAO:0000232 "this class is the superclass of 'rectum', which is currently reserved for the vertebrate structure. May be merged in future." xsd:string [Term] id: UBERON:0006868 name: seminal fluid secreting gland namespace: uberon def: "A gland that secretes a seminal fluid." [OBOL:automatic] subset: grouping_class subset: organ_slim xref: FBbt:00004958 xref: WBbt:0006870 is_a: UBERON:0005399 ! male reproductive gland intersection_of: UBERON:0002530 ! gland intersection_of: produces UBERON:0006530 ! seminal fluid relationship: part_of UBERON:0006947 ! male genital duct relationship: produces UBERON:0006530 ! seminal fluid [Term] id: UBERON:0006871 name: embryonic footplate namespace: uberon alt_id: UBERON:0004343 def: "The distal elements of the developing limb of vertebrates that will give rise to the pes (foot)." [https://github.com/obophenotype/mammalian-phenotype-ontology/issues/2218, MGI:csmith, MP:0004576, UBERON:cjm] subset: pheno_slim synonym: "distal part of hindlimb bud" RELATED [EMAPA:17249] synonym: "foot disk" RELATED [] synonym: "foot plate" BROAD [] synonym: "footplate" BROAD [] xref: EHDAA:5143 xref: EHDAA:6096 xref: EMAPA:17249 xref: FMA:296800 xref: NCIT:C34177 xref: UMLS:C1517291 {source="ncithesaurus:Foot_Plate"} is_a: UBERON:0010130 ! embryonic autopod plate intersection_of: UBERON:0010130 ! embryonic autopod plate intersection_of: has_potential_to_develop_into UBERON:0002387 ! pes relationship: develops_from UBERON:0005418 ! hindlimb bud relationship: has_potential_to_develop_into UBERON:0002387 ! pes property_value: UBPROP:0000012 "EHDAA2 does not have a single class for footplate, but includes epithelium, mesenchyme and AER" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0006872 name: handplate apical ectodermal ridge namespace: uberon def: "An apical ectodermal ridge that is part of a handplate." [OBOL:automatic] xref: EHDAA2:0000729 xref: EMAPA:17247 is_a: UBERON:0004356 ! apical ectodermal ridge intersection_of: UBERON:0004356 ! apical ectodermal ridge intersection_of: part_of UBERON:0006875 ! embryonic handplate relationship: part_of UBERON:0006875 ! embryonic handplate [Term] id: UBERON:0006875 name: embryonic handplate namespace: uberon def: "The distal elements of the developing limb of vertebrates that will give rise to the manus (hand)." [MGI:csmith, MP:0004576, UBERON:cjm] synonym: "distal part of forelimb bud" RELATED [EMAPA:17245] synonym: "hand plate" EXACT [] synonym: "handplate" EXACT [] xref: EHDAA:4194 xref: EHDAA:6242 xref: EMAPA:17245 xref: FMA:296794 xref: NCIT:C34185 xref: UMLS:C1512334 {source="ncithesaurus:Hand_Plate"} is_a: UBERON:0010130 ! embryonic autopod plate intersection_of: UBERON:0010130 ! embryonic autopod plate intersection_of: has_potential_to_develop_into UBERON:0002398 ! manus relationship: develops_from UBERON:0005417 ! forelimb bud relationship: has_potential_to_develop_into UBERON:0002398 ! manus [Term] id: UBERON:0006876 name: vasculature of organ namespace: uberon def: "A vasculature that is part of a organ." [OBOL:automatic] subset: non_informative synonym: "organ vasculature" EXACT [FMA:74612] synonym: "set of blood vessels of organ" EXACT [FMA:74612] xref: FMA:74612 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000062 ! organ relationship: part_of UBERON:0000062 ! organ [Term] id: UBERON:0006877 name: vasculature of liver namespace: uberon def: "A vasculature that is part of a liver." [OBOL:automatic] subset: pheno_slim synonym: "hepatic vascular element" RELATED [EMAPA:35501] synonym: "hepatic vasculature" EXACT [FMA:73748] synonym: "liver vascular element" RELATED [EMAPA:35501] synonym: "liver vascular system" RELATED [EHDAA2:0003454] xref: EHDAA2:0003454 xref: EMAPA:35501 xref: FMA:73748 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 ! liver property_value: UBPROP:0000012 "the EHDAA2 term and the FMA term may not be exact equivalents - check" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0006904 name: head mesenchyme from mesoderm namespace: uberon def: "A head mesenchyme that develops_from a mesoderm." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "cranial mesoderm" RELATED [UBERON:0005280] synonym: "head mesenchyme derived from mesoderm" EXACT [] synonym: "head mesenchyme from head mesoderm" EXACT [EHDAA2:0001118] synonym: "head mesenchyme from mesoderm" EXACT [] synonym: "head mesoderm" RELATED [AAO:0011051, UBERON:0005280] synonym: "mesenchyme derived from head mesoderm" EXACT [EHDAA:1057] synonym: "mesenchyme from head mesoderm" EXACT [] xref: AAO:0011051 xref: EFO:0003337 xref: EFO:0003603 xref: EHDAA2:0001118 xref: EHDAA:655 xref: EMAPA:16099 xref: EMAPA_RETIRED:16270 xref: FMA:293859 xref: TAO:0000998 xref: VHOG:0000185 xref: XAO:0000053 xref: ZFA:0000998 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005253 {source="ZFA"} ! head mesenchyme intersection_of: UBERON:0005253 ! head mesenchyme intersection_of: develops_from UBERON:0000926 ! mesoderm relationship: develops_from UBERON:0003063 {source="EHDAA2", source="XAO"} ! prechordal plate property_value: editor_note "merged in 'head mesoderm' from XAO/AAO and EFO here. Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme" xsd:string [Term] id: UBERON:0006905 name: mandibular process mesenchyme namespace: uberon def: "Mesenchyme that is part of a mandibular prominence." [OBOL:automatic] synonym: "mesenchyme of mandibular process" EXACT [EMAPA:17357] synonym: "mesenchyme of mandibular prominence" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001062 xref: EHDAA:5861 xref: EHDAA:5873 xref: EMAPA:17357 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005253 ! head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005867 ! mandibular prominence relationship: part_of UBERON:0005867 ! mandibular prominence [Term] id: UBERON:0006909 name: lumen of digestive tract namespace: uberon def: "An anatomical space that surrounded_by a digestive tract." [OBOL:automatic] synonym: "digestive tract lumen" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "gut cavity" EXACT [BTO:0000349] synonym: "gut lumen" EXACT [FMA:45677] synonym: "lumen of alimentary tract" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "lumen of digestive tract" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "lumen of gut" EXACT [FMA:45677] xref: BTO:0000349 xref: EMAPA:32908 xref: FMA:45677 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001555 ! digestive tract relationship: luminal_space_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0006913 name: lip epithelium namespace: uberon def: "An epithelium that is part of a lip." [OBOL:automatic] xref: BTO:0004468 xref: TAO:0005334 xref: ZFA:0005334 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001833 ! lip relationship: part_of UBERON:0001833 ! lip property_value: UBPROP:0000001 "The thick, high squamous-stratified epithelium that covers the lips. It contains abundant melanocytes, many mucous cells and has well differentiated taste buds.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005334", ontology="TAO", source="ZFIN:ZDB-PUB-060921-12"} [Term] id: UBERON:0006914 name: squamous epithelium namespace: uberon def: "An epithelium characterised by its most superficial layer consisting of squamous epithelial cells." [Wikipedia:Squamous_epithelium] xref: BTO:0002072 xref: NCIT:C12848 xref: SCTID:40118003 xref: UMLS:C0221909 {source="ncithesaurus:Squamous_Epithelium"} xref: Wikipedia:Squamous_epithelium is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: has_part CL:0000076 ! squamous epithelial cell relationship: has_part CL:0000076 ! squamous epithelial cell property_value: UBPROP:0000012 "FBbt:00007028 (squamous epithelium) A type of epithelium that is made up of flattened cells which are arranged with their long axes in the plane of the epithelium" xsd:string {external_ontology="FBbt"} [Term] id: UBERON:0006915 name: stratified squamous epithelium namespace: uberon def: "Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA]." [FMA:45563, Wikipedia:Stratified_squamous_epithelium] subset: pheno_slim synonym: "epithelium stratificatum squamosum" EXACT [FMA:45563] xref: FMA:45563 xref: NCIT:C13180 xref: UMLS:C0836131 {source="ncithesaurus:Stratified_Squamous_Epithelium"} xref: Wikipedia:Stratified_squamous_epithelium is_a: UBERON:0000486 ! multilaminar epithelium is_a: UBERON:0006914 ! squamous epithelium intersection_of: UBERON:0000486 ! multilaminar epithelium intersection_of: has_part CL:0000076 ! squamous epithelial cell [Term] id: UBERON:0006916 name: non-keratinized epithelium of tongue namespace: uberon def: "A non-keratinized stratified squamous epithelium that is part of a tongue." [OBOL:automatic] xref: FMA:62130 is_a: UBERON:0006919 ! tongue squamous epithelium is_a: UBERON:0010304 ! non-keratinized stratified squamous epithelium intersection_of: UBERON:0010304 ! non-keratinized stratified squamous epithelium intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0006919 name: tongue squamous epithelium namespace: uberon def: "A squamous epithelium that is part of a tongue." [OBOL:automatic] subset: pheno_slim synonym: "squamous epithelium of tongue" EXACT [OBOL:automatic] xref: MA:0002786 is_a: UBERON:0002424 ! oral epithelium is_a: UBERON:0003357 ! epithelium of tongue is_a: UBERON:0006914 ! squamous epithelium intersection_of: UBERON:0006914 ! squamous epithelium intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0005020 ! mucosa of tongue property_value: UBPROP:0000012 "this is a singleton subclass of tongue epithelium in MA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0006920 name: esophagus squamous epithelium namespace: uberon def: "A squamous epithelium that is part of a esophagus." [OBOL:automatic] subset: pheno_slim synonym: "esophageal squamous epithelium" RELATED [OBOL:automatic] synonym: "squamous epithelium of esophagus" RELATED [OBOL:automatic] synonym: "squamous oesophageal epithelium" RELATED [MA:0001567] xref: BTO:0003635 xref: CALOHA:TS-1250 xref: EMAPA:35324 xref: MA:0001567 xref: NCIT:C49222 xref: UMLS:C1707950 {source="ncithesaurus:Esophageal_Squamous_Epithelium"} is_a: UBERON:0001976 ! epithelium of esophagus is_a: UBERON:0006914 ! squamous epithelium intersection_of: UBERON:0006914 ! squamous epithelium intersection_of: part_of UBERON:0001043 ! esophagus property_value: UBPROP:0000012 "MA introduces basal and squamous subtypes of esophagus epithelium; consider adding the FMA class 'epithelium of esophagus' here, because it is classified as squamous. BTO also has a singleton subclass" xsd:string {external_ontology="MA"} [Term] id: UBERON:0006921 name: stomach squamous epithelium namespace: uberon def: "A squamous epithelium that is part of a stomach." [OBOL:automatic] subset: pheno_slim xref: EMAPA:35824 xref: MA:0001611 is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0001276 ! epithelium of stomach intersection_of: UBERON:0006914 ! squamous epithelium intersection_of: part_of UBERON:0000945 ! stomach [Term] id: UBERON:0006924 name: stomach glandular epithelium namespace: uberon def: "A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands." [ISBN:0073040584] subset: pheno_slim synonym: "epithelium of gastric gland" NARROW [FMA:63458] synonym: "gastric gland epithelium" RELATED [FMA:63458] xref: EMAPA:17623 xref: EMAPA:35814 xref: FMA:63458 xref: MA:0002784 is_a: UBERON:0001276 ! epithelium of stomach is_a: UBERON:0006929 {source="FMA"} ! glandular columnar epithelium intersection_of: UBERON:0006799 ! glandular epithelium intersection_of: part_of UBERON:0000945 ! stomach relationship: has_part UBERON:0000325 ! gastric gland relationship: part_of UBERON:0006931 ! stomach glandular region mucosa property_value: editor_note "we follow Kardong in treating the glandular epithelium as a distinct entity, and thus as an epithelium which has glands; FMA has 'epithelium of gastric gland', which is part of the gastric gland." xsd:string [Term] id: UBERON:0006925 name: digestive system gland namespace: uberon def: "Any gland that is part of the digestive system." [UBERON:cjm] subset: organ_slim synonym: "digestive gland" RELATED [BTO:0000345] xref: AAO:0000130 xref: BTO:0000345 is_a: UBERON:0002368 ! endocrine gland is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0002368 ! endocrine gland intersection_of: part_of UBERON:0001007 ! digestive system [Term] id: UBERON:0006929 name: glandular columnar epithelium namespace: uberon def: "Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA]." [FMA:64800] xref: FMA:64800 xref: NCIT:C13182 xref: UMLS:C0225337 {source="ncithesaurus:Columnar_Epithelium"} is_a: UBERON:0000485 ! simple columnar epithelium is_a: UBERON:0006799 ! glandular epithelium intersection_of: UBERON:0000485 ! simple columnar epithelium intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell [Term] id: UBERON:0006930 name: glandular cuboidal epithelium namespace: uberon xref: FMA:66809 is_a: UBERON:0000484 ! simple cuboidal epithelium is_a: UBERON:0006799 ! glandular epithelium intersection_of: UBERON:0000484 ! simple cuboidal epithelium intersection_of: composed_primarily_of CL:0000150 ! glandular epithelial cell [Term] id: UBERON:0006931 name: stomach glandular region mucosa namespace: uberon def: "Stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region." [http://orcid.org/0000-0002-6601-2165] synonym: "stomach glandular region glandular mucous membrane" EXACT [EMAPA:27167] xref: EMAPA:27167 xref: MA:0001614 is_a: UBERON:0001199 ! mucosa of stomach intersection_of: UBERON:0001199 ! mucosa of stomach intersection_of: part_of UBERON:0011953 ! stomach glandular region relationship: part_of UBERON:0011953 ! stomach glandular region [Term] id: UBERON:0006934 name: sensory epithelium namespace: uberon def: "Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue." [BTO:0000314] synonym: "neuroepithelium" RELATED INCONSISTENT [BTO:0000314] xref: CALOHA:TS-0682 xref: FMA:62410 xref: SCTID:309045006 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000488 ! atypical epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: has_part CL:0000098 ! sensory epithelial cell relationship: has_part CL:0000098 ! sensory epithelial cell relationship: part_of UBERON:0000010 ! peripheral nervous system property_value: UBPROP:0000012 "note that the definition sourced from Dorlands say 'simple columnar', but FMA says atypical" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0006937 name: inner ear epithelium namespace: uberon def: "The epithelial cell layer containing the sensory hair cells and their associated sensory nerve terminals." [MGI:csmith, MP:0003308] subset: pheno_slim xref: EMAPA:32883 xref: MA:0001189 is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0015807 ! ear epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001846 ! internal ear relationship: part_of UBERON:0001846 ! internal ear [Term] id: UBERON:0006938 name: pinna surface epithelium namespace: uberon def: "An epithelium that is part of a pinna." [OBOL:automatic] xref: EHDAA2:0001470 xref: EHDAA:8983 xref: EMAPA:17592 xref: VHOG:0000632 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0015814 ! outer ear epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001757 ! pinna relationship: part_of UBERON:0001757 ! pinna [Term] id: UBERON:0006946 name: efferent duct namespace: uberon def: "The efferent ducts (or efferent ductules or ductuli efferentes) connect the rete testis with the initial section of the epididymis. The ductuli are unilaminar and composed of columnar ciliated and non-ciliated (absorptive) cells. The ciliated cells serve to stir the luminal fluids, possibly to help ensure homogeneous absorption of water from the fluid produced by the testis, which results in an increase in the concentration of luminal sperm. The epithelium is surrounded by a band of smooth muscle that helps to propel the sperm toward the epididymis." [Wikipedia:Efferent_ducts] subset: pheno_slim synonym: "ductuli efferentes testis" RELATED LATIN [Wikipedia:Efferent_ducts] synonym: "efferent ductule" EXACT [FMA:19081, Wikipedia:Efferent_ducts] synonym: "seminal duct" EXACT [] synonym: "vasa efferentia" RELATED [AAO:0010532, Wikipedia:Efferent_ducts] xref: AAO:0010532 xref: EMAPA:18993 xref: FMA:19081 xref: MA:0000398 xref: NCIT:C32492 xref: UMLS:C0228013 {source="ncithesaurus:Efferent_Ductule"} xref: Wikipedia:Efferent_ducts is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system relationship: channel_for CL:0000019 ! sperm relationship: channels_from UBERON:0003959 ! rete testis relationship: channels_into UBERON:0001301 ! epididymis relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0006947 {source="FMA"} ! male genital duct property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b5/Hodenschema.svg" xsd:anyURI property_value: UBPROP:0000001 "Any of a group ranging from one to twelve (varies in species) small seminal ducts per testis which transport sperm from the testes to the kidney.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010532", ontology="AAO", source="AAO:BJB"} property_value: UBPROP:0000008 "There are two basic designs for efferent ductule structure: a) multiple entries into the epididymis, as seen in most large mammals. In humans and other large mammals, there are approximately 15-20 efferent ducts, which also occupy nearly one third of the head of the epididymis. b) single entry, as seen in most small animals such as rodents, whereby the 3-6 ductules merge into a single small ductule prior to entering the epididymis" xsd:string property_value: UBPROP:0000012 "Check EMAPA" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0006947 name: male genital duct namespace: uberon alt_id: UBERON:0010140 def: "A duct or series of ducts that transports sperm from the gonad. In mammals this is from the seminiferous tubules through rete testis, vas efferentia, epididymis, vas deferens, ejeculatory duct to the urethra." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "sperm duct" EXACT [ZFA:0001268] synonym: "sperm ducts" EXACT PLURAL [TAO:0001268] xref: FMA:55678 xref: TAO:0001268 xref: ZFA:0001268 is_a: UBERON:0000025 ! tube is_a: UBERON:0005904 ! duct of male reproductive system is_a: UBERON:0015212 ! lateral structure relationship: channel_for UBERON:0001968 ! semen relationship: channels_from UBERON:0000473 ! testis relationship: in_lateral_side_of UBERON:0004054 {source="FMA-abduced-lr"} ! internal male genitalia relationship: part_of UBERON:0004054 ! internal male genitalia property_value: UBPROP:0000008 "we use this as a generic grouping class for a number of taxa" xsd:string property_value: UBPROP:0000012 "in FMA includes as parts: seminal vesicle, efferent ductule (vas efferentia), epididymis, deferent duct (vas deferens), ejaculatory duct" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0006948 name: efferent duct epithelium namespace: uberon def: "An epithelium that is part of a efferent duct." [OBOL:automatic] synonym: "epithelium of efferent ductule of testis" EXACT [FMA:19195] xref: EMAPA:29747 xref: FMA:19195 xref: MA:0001734 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006946 ! efferent duct relationship: part_of UBERON:0006946 ! efferent duct [Term] id: UBERON:0006953 name: ejaculatory duct epithelium namespace: uberon def: "The ejaculatory duct epithelium is composed of cuboidal to columnar cells between or through which project the terminal parts of the ducts of the unicellular prostate glands." [PMID:1238970] xref: BTO:0002618 xref: EMAPA:29786 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000999 ! ejaculatory duct relationship: part_of UBERON:0000999 ! ejaculatory duct property_value: editor_note "TODO - split off insect classes" xsd:string [Term] id: UBERON:0006955 name: uterine epithelium namespace: uberon def: "An epithelium that is part of a uterus." [OBOL:automatic] synonym: "uterus epithelium" RELATED [BTO:0003082] xref: BTO:0003082 is_a: UBERON:0004804 ! oviduct epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus [Term] id: UBERON:0006960 name: ovary stroma namespace: uberon def: "The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis." [Wikipedia:Stroma_of_ovary] subset: human_reference_atlas synonym: "interstitial tissue of ovary" EXACT [FMA:18626] synonym: "ovarian stroma" EXACT [FMA:18626] synonym: "ovary stroma" EXACT [MA:0002991] synonym: "stroma of the ovary" EXACT [Wikipedia:Stroma_of_ovary] synonym: "stroma ovarica" EXACT [FMA:18626] synonym: "stroma ovarii" RELATED LATIN [Wikipedia:Stroma_of_ovary] xref: CALOHA:TS-1246 xref: EMAPA:28880 xref: FMA:18626 xref: MA:0002991 xref: NCIT:C33638 xref: SCTID:259306002 xref: UMLS:C0737271 {source="ncithesaurus:Stroma_of_the_Ovarian_Cortex"} xref: Wikipedia:Stroma_of_ovary is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003891 ! stroma is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0000992 ! ovary relationship: has_part CL:0002095 {source="FMA"} ! hilus cell of ovary relationship: part_of UBERON:0000992 ! ovary property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0006965 name: vascular cord namespace: uberon def: "The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]." [GO:0072360, ZFA:0005077] subset: efo_slim xref: EFO:0003709 xref: TAO:0005077 xref: ZFA:0005077 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0005423 ! developing anatomical structure relationship: has_part CL:0000115 ! endothelial cell relationship: has_part CL:0000566 ! angioblastic mesenchymal cell relationship: part_of UBERON:0014903 ! primordial vasculature relationship: site_of GO:0048754 ! branching morphogenesis of an epithelial tube [Term] id: UBERON:0006966 name: coronary capillary namespace: uberon def: "A capillary that is part of the coronary system." [http://orcid.org/0000-0002-6601-2165] synonym: "heart capillary" EXACT [GO:0003248] xref: ZFA:0005813 is_a: UBERON:0001982 ! capillary is_a: UBERON:0003498 ! heart blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0000948 ! heart [Term] id: UBERON:0006967 name: horn namespace: uberon def: "A pointed projection of the skin on the head of various animals, consisting of a covering of horn (keratin and other proteins) surrounding a core of living bone." [Wikipedia:Horn_(anatomy)] subset: pheno_slim xref: GAID:1225 xref: MESH:D006733 xref: SCTID:69221006 xref: Wikipedia:Horn_(anatomy) is_a: UBERON:0006969 ! cranial appendage relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: surrounds UBERON:0001474 ! bone element property_value: RO:0002161 NCBITaxon:9606 {source="ISBN:9780716717553"} [Term] id: UBERON:0006969 name: cranial appendage namespace: uberon def: "An anatomical projection that is part of and protrudes from the head." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0004529 ! anatomical projection relationship: part_of UBERON:0000033 ! head property_value: editor_note "revisit after CARO2 appendage issue is sorted. Note that antennae are appendages that protrude from the head" xsd:string [Term] id: UBERON:0006970 name: bony core of horn namespace: uberon is_a: UBERON:0004530 ! bony projection relationship: part_of UBERON:0006967 ! horn [Term] id: UBERON:0006983 name: anatomical point namespace: uberon def: "Non-material anatomical entity of zero dimension, which forms a boundary of an anatomical line or surface." [FMA:9658, http://orcid.org/0000-0001-9114-8737] subset: common_anatomy subset: upper_level xref: AAO:0010266 xref: AEO:0000009 xref: BILA:0000009 xref: CARO:0000009 xref: EHDAA2:0003009 xref: FMA:9658 xref: TAO:0001839 is_a: UBERON:0000466 ! immaterial anatomical entity property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0006984 name: anatomical surface namespace: uberon def: "A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n." [CARO:0001002] comment: Old definition: 'Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures.' Note, in the new definition, the space referred to is not necessarily an anatomical space. It may be the outside of an organism. subset: upper_level xref: BILA:0000010 xref: CARO:0001002 xref: EHDAA2_RETIRED:0003192 xref: FMA:24137 xref: NCIT:C34022 xref: UMLS:C1515977 {source="ncithesaurus:Anatomic_Surface"} is_a: UBERON:0010199 {notes="via morphological boundary in CARO"} ! bona-fide anatomical boundary [Term] id: UBERON:0007005 name: cardiogenic splanchnic mesoderm namespace: uberon def: "The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]." [http://www.drugs.com/dict/cardiogenic-mesoderm.html, https://github.com/obophenotype/insect_neuroanatomy_ontology/issues/7, XAO:0000235] subset: efo_slim subset: pheno_slim synonym: "cardiac mesoderm" RELATED [XAO:0000235] synonym: "cardiogenic mesoderm" RELATED [http://www.drugs.com/dict/cardiogenic-mesoderm.html] synonym: "cardiogenic region" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "cardiogenic splanchnopleure" EXACT [EHDAA2:0000214] synonym: "heart primordia" RELATED [XAO:0000235] xref: AAO:0011021 xref: BILA:0000051 xref: EFO:0000315 xref: EHDAA2:0000214 xref: EHDAA:385 xref: FMA:293143 xref: SCTID:360387000 xref: VHOG:0001641 xref: XAO:0000235 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: developmentally_induced_by UBERON:0009881 ! anterior lateral plate mesoderm relationship: develops_from UBERON:0004872 ! splanchnic layer of lateral plate mesoderm relationship: part_of UBERON:0004140 ! primary heart field relationship: part_of UBERON:0009881 ! anterior lateral plate mesoderm property_value: editor_note "consider FBbt:00005541 ! cardiogenic mesoderm" xsd:string property_value: editor_note "review EHDAA2 placement" xsd:string [Term] id: UBERON:0007010 name: cleaving embryo namespace: uberon def: "Organism at the cleavage stage." [OBOL:automatic] xref: BILA:0000058 is_a: UBERON:0000922 ! embryo intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_ends_with UBERON:0000107 ! cleavage stage intersection_of: existence_starts_with UBERON:0000107 ! cleavage stage relationship: existence_ends_with UBERON:0000107 ! cleavage stage relationship: existence_starts_with UBERON:0000107 ! cleavage stage [Term] id: UBERON:0007021 name: sexually immature organism namespace: uberon def: "A multicellular organism that is at the juvenile stage." [OBOL:automatic] synonym: "juvenile" BROAD [] synonym: "juvenile organism" EXACT [BILA:0000076] synonym: "juveniles" EXACT PLURAL [TAO:0002047] xref: BILA:0000076 xref: http://neurolex.org/wiki/Category\:Juvenile_organism xref: TAO:0002047 is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_ends_with UBERON:0000112 ! sexually immature stage intersection_of: existence_starts_with UBERON:0000112 ! sexually immature stage relationship: existence_ends_with UBERON:0000112 ! sexually immature stage relationship: existence_starts_with UBERON:0000112 ! sexually immature stage relationship: has_quality PATO:0001190 ! juvenile property_value: UBPROP:0000001 "Whole organism that is not fully grown or sexually mature.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002047", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0007023 name: adult organism namespace: uberon def: "A multicellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage." [OBOL:automatic] synonym: "adult" BROAD [] synonym: "adults" EXACT PLURAL [TAO:0002046] xref: BILA:0000078 xref: FBbt:00003004 xref: galen:Adult xref: HAO:0000087 xref: http://neurolex.org/wiki/Category\:Adult_organism xref: NCIT:C17600 xref: TAO:0002046 xref: UMLS:C0001675 {source="ncithesaurus:Adult"} is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_ends_with UBERON:0000113 ! post-juvenile adult stage intersection_of: existence_starts_with UBERON:0000113 ! post-juvenile adult stage relationship: existence_ends_with UBERON:0000113 ! post-juvenile adult stage relationship: existence_starts_with UBERON:0000113 ! post-juvenile adult stage property_value: UBPROP:0000001 "Whole organism that is fully grown or sexually mature.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002046", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0007026 name: presumptive gut namespace: uberon synonym: "embryonic digestive tube" RELATED [] synonym: "future digestive tract" EXACT [] synonym: "future digestive tube" EXACT [] synonym: "future gut" EXACT [] synonym: "primitive gut" EXACT [] synonym: "primordial digestive tube" RELATED [] synonym: "primordial gut" RELATED [] xref: BILA:0000084 xref: NCIT:C34268 xref: SCTID:360394002 xref: UMLS:C1514442 {source="ncithesaurus:Primordial_Gut"} is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001555 ! digestive tract relationship: existence_starts_during UBERON:0000109 ! gastrula stage relationship: has_developmental_contribution_from UBERON:0000925 ! endoderm relationship: has_developmental_contribution_from UBERON:0000926 ! mesoderm relationship: has_potential_to_develop_into UBERON:0001555 ! digestive tract property_value: UBPROP:0000011 "The endodermal cells generate only the lining of the digestive tube and its glands; mesodermal mesenchyme cells will surround this tube to provide the muscles for peristalsis" xsd:string {source="NCBIBook:NBK10107"} [Term] id: UBERON:0007037 name: mechanosensory system namespace: uberon xref: BILA:0000142 is_a: UBERON:0001032 ! sensory system intersection_of: UBERON:0001032 ! sensory system intersection_of: capable_of GO:0050954 ! sensory perception of mechanical stimulus relationship: capable_of GO:0050954 ! sensory perception of mechanical stimulus [Term] id: UBERON:0007098 name: mandibular neural crest namespace: uberon def: "Cranial neural crest that migrates into the mandibular arch." [ZFA:0007064] xref: TAO:0007064 xref: XAO:0000024 xref: ZFA:0007064 is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest relationship: part_of UBERON:0003852 {source="ZFA"} ! rhombencephalon neural crest [Term] id: UBERON:0007099 name: hyoid neural crest namespace: uberon def: "Cranial neural crest that migrates into the hyoid arch." [ZFA:0007065] synonym: "hyoid crest" EXACT [XAO:0000025] xref: TAO:0007065 xref: XAO:0000025 xref: ZFA:0007065 is_a: UBERON:0003099 {source="ZFA"} ! cranial neural crest relationship: part_of UBERON:0003852 {source="ZFA"} ! rhombencephalon neural crest [Term] id: UBERON:0007100 name: primary circulatory organ namespace: uberon def: "A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]." [GO:0007507] comment: Gene notes: Bmp, Nkx, Gata subset: grouping_class synonym: "adult heart" RELATED [FBbt:00003154] synonym: "dorsal tube" NARROW [Wikipedia:Heart] synonym: "heart" NARROW [GO:0007507] xref: http://www.sciencemag.org/content/313/5795/1922/F1.large.jpg xref: SPD:0000130 xref: TADS:0000147 is_a: UBERON:0015228 ! circulatory organ intersection_of: UBERON:0015228 ! circulatory organ intersection_of: capable_of GO:0008015 ! blood circulation relationship: capable_of GO:0008015 {notes="GO uses blood circulation generically to include the haemolymphatic fluid of arthropods"} ! blood circulation relationship: has_part CL:0002494 ! cardiocyte property_value: UBPROP:0000008 "note we reserve the subclass 'heart' from the vertebrate multi-chambered heart. 'The first heart-like organ is believed to have appeared 500my ago in an ancestral bilaterian'. Amniotes: four-chambered heart. Amphibians: two atria, one ventricle, pulmonary; fish: single atrium and ventricle; amphioxus: tubular, non-striated, closed, unidirectional; ascidians: tubular, striated, open, bidirectional; arthropods: tubular, open; C elegans: contractile pharynx; Cnideria: striated muscle cells associated with gastrodermis" xsd:string [Term] id: UBERON:0007106 name: chorionic villus namespace: uberon def: "One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta." [BTO:0001161, Wikipedia:Chorionic_villi] subset: human_reference_atlas synonym: "chorionic villi" RELATED PLURAL [MESH:A16.254.403.473.200] synonym: "chorionic villous" RELATED [Wikipedia:Chorionic_villi] synonym: "chorionic villus" RELATED [GAID:1300] synonym: "embryonic part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "embryonic placenta" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "fetal part of placenta" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "fetal placenta" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "placental villi" RELATED PLURAL [GAID:1300] synonym: "placental villous" RELATED [] synonym: "placental villus" RELATED [GAID:1300] synonym: "villous chorion" RELATED [] synonym: "villous of placenta" RELATED [] xref: BTO:0001161 xref: EHDAA2:0004717 xref: MESH:D002824 xref: NCIT:C34125 xref: SCTID:360403003 xref: UMLS:C0008508 {source="ncithesaurus:Chorionic_Villus"} xref: Wikipedia:Chorionic_villi is_a: UBERON:0000478 ! extraembryonic structure is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0004027 {source="MP-def"} ! chorionic plate relationship: part_of UBERON:0003124 {source="BTO"} ! chorion membrane property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/1e/Gray29.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "The mouse and human placentas have labyrinthine and villous types of interdigitation between maternal and fetal tissues, respectively" xsd:string property_value: UBPROP:0000010 "The bulk of the villi consist of connective tissues in which blood vessels are found. Most of the cells in the connective tissue core of the villi are fibroblasts. Macrophages known as Hofbauer cells are also present." xsd:string [Term] id: UBERON:0007115 name: deciduous tooth namespace: uberon def: "One of the first set of teeth in the growth development of humans and many other mammals[WP]." [Wikipedia:Deciduous_teeth] comment: GAT in FMA. subset: pheno_slim synonym: "dentes decidui" RELATED LATIN [Wikipedia:Deciduous_teeth] synonym: "primary tooth" EXACT [FMA:55655] synonym: "temporary tooth" EXACT [FMA:55655] xref: FMA:55655 xref: GAID:1266 xref: MESH:D014094 xref: NCIT:C33745 xref: SCTID:245612004 xref: UMLS:C0040455 {source="ncithesaurus:Temporary_Tooth"} xref: Wikipedia:Deciduous_teeth is_a: UBERON:0001091 ! calcareous tooth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: part_of UBERON:0007116 ! primary dentition disjoint_from: UBERON:0007775 ! secondary tooth relationship: part_of UBERON:0007116 ! primary dentition property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Deciduous_teeth_by_David_Shankbone.jpg" xsd:anyURI [Term] id: UBERON:0007116 name: primary dentition namespace: uberon def: "The set of teeth first in order or time of development that will be replaced by permanent dentition upon their loss." [MESH:A14.254.245] subset: pheno_slim synonym: "baby teeth" EXACT [FMA:75151] synonym: "deciduous dentition" RELATED [GAID:1252] synonym: "deciduous teeth" EXACT [FMA:75151] synonym: "dentes decidui" EXACT LATIN [FMA:75151, FMA:TA] synonym: "milk teeth" EXACT [FMA:75151] synonym: "primary teeth" EXACT [FMA:75151, GAID:1266] synonym: "set of deciduous teeth" EXACT [FMA:75151] synonym: "set of primary teeth" EXACT [FMA:75151] synonym: "tooth of primary dentition" EXACT [] xref: FMA:75151 xref: GAID:1252 xref: MESH:D014094 is_a: UBERON:0003672 ! dentition [Term] id: UBERON:0007119 name: neck of femur namespace: uberon def: "The femur neck or neck of the femur is a flattened pyramidal process of bone, connecting the femoral head with the femoral shaft, and forming with the latter a wide angle opening medialward." [Wikipedia:Femur_neck] subset: human_reference_atlas subset: pheno_slim synonym: "collum femoris" RELATED LATIN [Wikipedia:Femur_neck] synonym: "femoral neck" EXACT [FMA:42385] synonym: "femur neck" RELATED [Wikipedia:Femur_neck] synonym: "neck of the femur" RELATED [Wikipedia:Femur_neck] xref: FMA:42385 xref: GAID:201 xref: galen:NeckOfFemur xref: MESH:D005272 xref: NCIT:C61563 xref: SCTID:361792007 xref: UMLS:C0015815 {source="ncithesaurus:Femoral_Neck"} xref: Wikipedia:Femur_neck is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0018664 ! neck of bone element intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0000981 ! femur relationship: part_of UBERON:0006863 ! proximal metaphysis of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray243.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007120 name: premolar tooth namespace: uberon def: "The premolar teeth or bicuspids are transitional teeth located between the canine and molar teeth." [Wikipedia:Premolar] subset: pheno_slim synonym: "bicuspid" RELATED [Wikipedia:Premolar] synonym: "bicuspid teeth" RELATED [Wikipedia:Premolar] synonym: "bicuspid tooth" RELATED [Wikipedia:Premolar] synonym: "bicuspids" RELATED [Wikipedia:Premolar] synonym: "biscuspid" RELATED [Wikipedia:Premolar] synonym: "dens premolaris" RELATED [Wikipedia:Premolar] synonym: "dentes premolares" RELATED LATIN [Wikipedia:Premolar] synonym: "mandibular bicuspid" RELATED [Wikipedia:Premolar] synonym: "maxillary bicuspid" RELATED [Wikipedia:Premolar] synonym: "maxillary premolar" RELATED [Wikipedia:Premolar] synonym: "pm3 (dentistry)" RELATED [Wikipedia:Premolar] synonym: "praemolares" RELATED [Wikipedia:Premolar] synonym: "premolar" RELATED [Wikipedia:Premolar] synonym: "premolar teeth" RELATED [Wikipedia:Premolar] synonym: "premolar tooth" RELATED [Wikipedia:Premolar] synonym: "premolars" RELATED [Wikipedia:Premolar] synonym: "præmolares" RELATED [Wikipedia:Premolar] synonym: "secondary premolar tooth" NARROW [FMA:55637] xref: FMA:55637 xref: GAID:1261 xref: MESH:D001641 xref: NCIT:C32201 xref: SCTID:304572005 xref: UMLS:C1704302 {source="ncithesaurus:Bicuspid_Tooth"} xref: Wikipedia:Premolar is_a: UBERON:0013164 ! molariform tooth property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/6c/Gray1003.png" xsd:anyURI property_value: RO:0002161 NCBITaxon:337687 {notes="Although there are a few exceptions, the dental formula for the great majority of cricetids is 1.0.0.3", source="Wikipedia:Cricetidae"} property_value: UBPROP:0000008 "In humans, there are two premolars per quadrant, making eight premolars total in the mouth. They have at least two cusps. Premolars can be considered as a 'transitional tooth' during chewing, or mastication. It has properties of both the anterior canines and posterior molars, and so food can be transferred from the canines to the premolars and finally to the molars for grinding, instead of directly from the canines to the molars. The premolars in humans are the maxillary first premolar, maxillary second premolar, mandibular first premolar, and the mandibular second premolar. There is always one large buccal cusp, especially so in the mandibular first premolar. The lower second premolar almost always presents with two lingual cusps. Premolar teeth by definition are permanent teeth distal to the canines preceded by deciduous molars. In primitive mammals there are four premolars per quadrant. The most mesial two have been lost in Catarrhines. Paleontologists refer to human premolars as Pm3 and Pm4" xsd:string [Term] id: UBERON:0007122 name: pharyngeal pouch 1 namespace: uberon alt_id: UBERON:0005718 def: "A pharyngeal pouch that is between pharyngeal arches 1 and 2." [ISBN:0124020607, PMID:16313389, VHOG:0000970] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "1st arch branchial pouch" EXACT [EHDAA2:0000013] synonym: "1st arch branchial pouch endoderm" EXACT [EHDAA2:0000016] synonym: "1st arch pouch endoderm" EXACT [EHDAA2:0000016] synonym: "1st branchial pouch" EXACT [] synonym: "1st pharyngeal pouch endoderm" EXACT [VHOG:0000555] synonym: "first arch pharyngeal pouch" EXACT [OBOL:automatic] synonym: "first pharyngeal pouch" RELATED [VHOG:0000970] synonym: "first visceral pouch" EXACT [XAO:0000102] synonym: "hyomandibular pouch" EXACT [] synonym: "pharyngeal pouches 1" EXACT PLURAL [ZFA:0001128] synonym: "visceral pouch 1" EXACT [XAO:0000102] xref: AAO:0011114 xref: EFO:0003631 xref: EHDAA2:0000016 xref: EMAPA:16124 xref: EMAPA:16125 xref: FMA:295668 xref: NCIT:C34176 xref: SCTID:345248006 xref: TAO:0001128 xref: UMLS:C0231068 {source="ncithesaurus:First_Pharyngeal_Pouch"} xref: VHOG:0000555 xref: VHOG:0000970 xref: Wikipedia:Pharyngeal_pouch_(embryology)#First_pouch xref: XAO:0000102 xref: ZFA:0001128 is_a: UBERON:0004117 ! pharyngeal pouch intersection_of: UBERON:0004117 ! pharyngeal pouch intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 intersection_of: overlaps UBERON:0004362 ! pharyngeal arch 1 relationship: overlaps UBERON:0003066 ! pharyngeal arch 2 relationship: overlaps UBERON:0004362 ! pharyngeal arch 1 property_value: UBPROP:0000001 ". [][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000970", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "In all jawed vertebrates the first arch forms the jaw, while the second arch forms the hyoid apparatus. These two arches are separated by the first pharyngeal pouch and cleft.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000970", ontology="VHOG", source="DOI:10.1016/j.semcdb.2010.01.022 Grevellec A, Tucker AS, The pharyngeal pouches and clefts: development, evolution, structure and derivatives. Seminars in Cell and Developmental Biology (2010)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "The endoderm lines the future auditory tube (Pharyngotympanic Eustachian tube) , middle ear, mastoid antrum, and inner layer of the tympanic membrane. & origin of Mandibular nerve & Maxillary artery" xsd:string {source="WP"} property_value: UBPROP:0000012 "we use adjacency relations rather than part_of, as in EHDAA2." xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0007123 name: pharyngeal pouch 2 namespace: uberon alt_id: UBERON:0005715 def: "A pharyngeal puch that is between the pharyngeal arches 2 and 3." [ISBN:0124020607, PMID:16313389] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "2nd arch branchial pouch" EXACT [RETIRED_EHDAA2:0000060] synonym: "2nd arch branchial pouch endoderm" EXACT [EHDAA2:0000061] synonym: "2nd arch pouch endoderm" EXACT [EHDAA2:0000058] synonym: "2nd branchial pouch" EXACT [] synonym: "2nd pharyngeal pouch endoderm" EXACT [VHOG:0000561] synonym: "pharyngeal pouches 2" EXACT PLURAL [ZFA:0001130] synonym: "second arch pharyngeal pouch" EXACT [OBOL:automatic] synonym: "second pharyngeal pouch" RELATED [VHOG:0000967] synonym: "second visceral pouch" EXACT [XAO:0000247] synonym: "visceral pouch 2" EXACT [XAO:0000247] xref: AAO:0011115 xref: EFO:0003633 xref: EHDAA2:0000058 xref: EMAPA:16275 xref: EMAPA:16276 xref: FMA:295676 xref: NCIT:C34289 xref: RETIRED_EHDAA2:0000060 xref: SCTID:345349000 xref: TAO:0001130 xref: UMLS:C0231069 {source="ncithesaurus:Second_Pharyngeal_Pouch"} xref: VHOG:0000561 xref: VHOG:0000967 xref: Wikipedia:Pharyngeal_pouch_(embryology)#Second_pouch xref: XAO:0000247 xref: ZFA:0001130 is_a: UBERON:0004117 ! pharyngeal pouch intersection_of: UBERON:0004117 ! pharyngeal pouch intersection_of: overlaps UBERON:0003066 ! pharyngeal arch 2 intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 relationship: overlaps UBERON:0003066 ! pharyngeal arch 2 relationship: overlaps UBERON:0003114 ! pharyngeal arch 3 property_value: UBPROP:0000001 "A pouch that is situated between the 2nd and 3rd pharyngeal arch. [ISBN:0124020607][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000967", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Second of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011115", ontology="AAO", source="ISBN:0-226-55763-4"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000967", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "the dorsal elongation of the second pouch endoderm of all mammals, with the exception of rodents, gives rise to the epithelial lining of palatine tonsils; in rodents, the ventral portion of the second pouch appears to degenerate whereas the remaining part is incorporated into the lateral border of the pharynx; it appears that rodents no longer require tonsils as their function is carried out by the NALT (Nose/Nasal-Associated Lymphoid Tissue) system in the upper respiratory tract." xsd:string property_value: UBPROP:0000011 "Contributes to the middle ear, epithelial lining of Crypts (spaces) of the palatine tonsils, supplied by the facial nerve" xsd:string {source="WP"} [Term] id: UBERON:0007124 name: pharyngeal pouch 3 namespace: uberon alt_id: UBERON:0005716 def: "A pharyngeal pouch that between pharyngeal arches 3 and 4." [ISBN:0124020607, PMID:16313389, Wikipedia:Pharyngeal_pouch_(embryology)#Third_pouch] subset: efo_slim subset: pheno_slim subset: vertebrate_core synonym: "3rd arch branchial pouch" EXACT [RETIRED_EHDAA2:0000076] synonym: "3rd arch branchial pouch endoderm" EXACT [EHDAA2:0000077] synonym: "3rd branchial pouch" EXACT [] synonym: "3rd pharyngeal pouch endoderm" EXACT [VHOG:0001030] synonym: "pharyngeal pouches 3" EXACT PLURAL [ZFA:0001131] synonym: "third arch pharyngeal pouch" EXACT [OBOL:automatic] synonym: "third pharyngeal pouch" RELATED [VHOG:0000966] synonym: "third visceral pouch" EXACT [XAO:0000251] synonym: "visceral pouch 3" EXACT [XAO:0000251] xref: AAO:0011116 xref: EFO:0003634 xref: EHDAA2:0000077 xref: EMAPA:16586 xref: FMA:295682 xref: NCIT:C34311 xref: RETIRED_EHDAA2:0000076 xref: SCTID:345450001 xref: TAO:0001131 xref: UMLS:C0231070 {source="ncithesaurus:Third_Pharyngeal_Pouch"} xref: VHOG:0000966 xref: VHOG:0001030 xref: Wikipedia:Pharyngeal_pouch_(embryology)#Third_pouch xref: XAO:0000251 xref: ZFA:0001131 is_a: UBERON:0004117 ! pharyngeal pouch intersection_of: UBERON:0004117 ! pharyngeal pouch intersection_of: overlaps UBERON:0003114 ! pharyngeal arch 3 intersection_of: overlaps UBERON:0003115 ! pharyngeal arch 4 relationship: overlaps UBERON:0003114 ! pharyngeal arch 3 relationship: overlaps UBERON:0003115 ! pharyngeal arch 4 property_value: UBPROP:0000001 "A pouch that is situated between the 3rd and 4th pharyngeal arch. [ISBN:0124020607][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000966", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000001 "Third of the pharyngeal (endodermal) evaginations between the visceral arches from which the Eustachian tube is derived; pouches 2-4 open as gill slits.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0011116", ontology="AAO", source="ISBN:0-226-55763-4"} property_value: UBPROP:0000003 "A conserved feature of all vertebrate embryos is the presence of a series of bulges on the lateral surface of the head, the pharyngeal arches; it is within these structures that the nerves, muscles and skeletal components of the pharyngeal apparatus are laid down. The pharyngeal arches are separated by endodermal outpocketings, the pharyngeal pouches.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000966", ontology="VHOG", source="DOI:10.1111/j.1469-7580.2005.00472.x Graham A, Okabe M and Quinlan R, The role of the endoderm in the development and evolution of the pharyngeal arches. J Anat (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000011 "The third pouch possesses Dorsal and Ventral wings. Derivatives of the dorsal wings include the inferior parathyroid glands, while the ventral wings fuse to form the cytoreticular cells of the thymus. The main nerve supply to the derivatives of this pouch is Cranial Nerve IX, glossopharyngeal nerve" xsd:string {source="WP"} [Term] id: UBERON:0007134 name: trunk ganglion namespace: uberon def: "Ganglion which is located in the trunk." [ZFIN:curator] subset: efo_slim synonym: "body ganglion" EXACT [MAT:0000344] synonym: "trunk ganglia" EXACT PLURAL [ZFA:0001573] xref: EFO:0000901 xref: MAT:0000344 xref: MIAA:0000344 xref: TAO:0001573 xref: ZFA:0001573 is_a: UBERON:0000045 ! ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0007135 name: neural keel namespace: uberon def: "An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section." [ZFIN:ZDB-PUB-961014-576] subset: efo_slim synonym: "presumptive central nervous system" RELATED [ZFA:0000131] xref: EFO:0003497 xref: TAO:0000131 xref: ZFA:0000131 is_a: UBERON:0016879 ! future central nervous system relationship: develops_from UBERON:0003075 ! neural plate property_value: UBPROP:0000001 "An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000131", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0007142 name: left internal carotid artery namespace: uberon def: "An internal carotid artery that branching_part_of a left common carotid artery plus branches." [OBOL:automatic] synonym: "arteria caritis interna sinistra" EXACT [FMA:4062] xref: EMAPA:16329 xref: FMA:4062 xref: SCTID:161452006 is_a: UBERON:0001532 ! internal carotid artery intersection_of: UBERON:0001532 ! internal carotid artery intersection_of: branching_part_of UBERON:0001536 ! left common carotid artery plus branches relationship: branching_part_of UBERON:0001536 ! left common carotid artery plus branches relationship: part_of UBERON:0001536 ! left common carotid artery plus branches [Term] id: UBERON:0007143 name: right internal carotid artery namespace: uberon def: "An internal carotid artery that branching_part_of a right common carotid artery plus branches." [OBOL:automatic] synonym: "arteria carotis interna dextra" EXACT [FMA:3949] xref: EMAPA:16330 xref: FMA:3949 xref: SCTID:161251001 is_a: UBERON:0001532 ! internal carotid artery intersection_of: UBERON:0001532 ! internal carotid artery intersection_of: branching_part_of UBERON:0001531 ! right common carotid artery plus branches relationship: branching_part_of UBERON:0001531 ! right common carotid artery plus branches relationship: part_of UBERON:0001531 ! right common carotid artery plus branches [Term] id: UBERON:0007144 name: embryonic post-anal tail namespace: uberon def: "An embryonic structure that will either develop into a post-anal tail or recede into a vestigial remnant of the tail." [http://orcid.org/0000-0002-6601-2165] synonym: "embryo tail" EXACT [FMA:85540] synonym: "embryonic tail" RELATED [FMA:85540] synonym: "tail of embryo" EXACT [FMA:85540] xref: EMAPA:16748 xref: FMA:85540 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0002533 ! post-anal tail bud relationship: transformation_of UBERON:0002533 ! post-anal tail bud property_value: UBPROP:0000011 "By the fourth week a clear tail is seen in the human embryo. It recedes after a few weeks and these tissues form what is commonly known as the tailbone (coccyx)." xsd:string [Term] id: UBERON:0007147 name: lumen of midgut namespace: uberon def: "An anatomical cavity that surrounded_by a midgut." [OBOL:automatic] synonym: "midgut lumen" EXACT [FMA:54366] xref: EMAPA:18377 xref: FMA:54366 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001045 ! midgut relationship: luminal_space_of UBERON:0001045 ! midgut relationship: part_of UBERON:0001045 ! midgut [Term] id: UBERON:0007148 name: lumen of hindgut namespace: uberon def: "An anatomical cavity that surrounded_by a hindgut." [OBOL:automatic] synonym: "hindgut lumen" EXACT [FMA:54367] xref: EMAPA:18396 xref: FMA:54367 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001046 ! hindgut relationship: luminal_space_of UBERON:0001046 ! hindgut relationship: part_of UBERON:0001046 ! hindgut [Term] id: UBERON:0007158 name: lumen of anal canal namespace: uberon def: "An anatomical cavity that surrounded_by a anal canal." [OBOL:automatic] synonym: "anal canal lumen" EXACT [FMA:17357] xref: EMAPA:18836 xref: FMA:17357 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000159 ! anal canal relationship: luminal_space_of UBERON:0000159 ! anal canal relationship: part_of UBERON:0000159 ! anal canal [Term] id: UBERON:0007159 name: lumen of colon namespace: uberon def: "An anatomical cavity that surrounded_by a colon." [OBOL:automatic] synonym: "colon lumen" EXACT [FMA:18374] synonym: "colonic lumen" RELATED [FMA:18374] xref: EMAPA:18945 xref: FMA:18374 xref: SCTID:362156004 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001155 ! colon relationship: luminal_space_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon [Term] id: UBERON:0007171 name: border of scapula namespace: uberon synonym: "scapular border" EXACT [FMA:23797] xref: EMAPA:25124 xref: FMA:23797 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0036304 ! anatomical border intersection_of: UBERON:0036304 ! anatomical border intersection_of: part_of UBERON:0006849 ! scapula relationship: part_of UBERON:0006849 ! scapula [Term] id: UBERON:0007172 name: angle of scapula namespace: uberon synonym: "scapular angle" EXACT [FMA:23800] xref: EMAPA:25125 xref: FMA:23800 is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0006849 ! scapula property_value: seeAlso "https://github.com/obophenotype/uberon/issues/58" xsd:anyURI [Term] id: UBERON:0007173 name: lateral border of scapula namespace: uberon def: "The lateral border (or axillary border, or margin) is the thickest of the three borders of the scapula. It begins above at the lower margin of the glenoid cavity, and inclines obliquely downward and backward to the inferior angle. Immediately below the glenoid cavity is a rough impression, the infraglenoid tuberosity, about 2.5 cm. in length, which gives origin to the long head of the Triceps brachii; in front of this is a longitudinal groove, which extends as far as the lower third of this border, and affords origin to part of the Subscapularis. The inferior third is thin and sharp, and serves for the attachment of a few fibers of the Teres major behind, and of the Subscapularis in front." [Wikipedia:Lateral_border_of_the_scapula] subset: human_reference_atlas synonym: "axillary border of scapula" EXACT [FMA:23239] synonym: "lateral border of scapula" EXACT [FMA:23239] synonym: "lateral part of scapula" RELATED [FMA:23239] synonym: "margo lateralis (scapula)" EXACT [FMA:23239] synonym: "margo lateralis scapulae" EXACT LATIN [FMA:23239, FMA:TA] xref: EMAPA:25126 xref: FMA:23239 xref: Wikipedia:Lateral_border_of_the_scapula is_a: UBERON:0007171 {source="EMAPA-modified"} ! border of scapula disjoint_from: UBERON:0007174 {source="lexical"} ! medial border of scapula property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007174 name: medial border of scapula namespace: uberon def: "The medial border of the scapula (vertebral border, medial margin) is the longest of the three borders, and extends from the medial to the inferior angle. It is arched, intermediate in thickness between the superior and the axillary borders, and the portion of it above the spine forms an obtuse angle with the part below. This border presents an anterior and a posterior lip, and an intermediate narrow area. The anterior lip affords attachment to the Serratus anterior; the posterior lip, to the Supraspinatus above the spine, the Infraspinatus below; the area between the two lips, to the Levator scapulC& above the triangular surface at the commencement of the spine, to the Rhomboideus minor on the edge of that surface, and to the Rhomboideus major below it; this last is attached by means of a fibrous arch, connected above to the lower part of the triangular surface at the base of the spine, and below to the lower part of the border." [Wikipedia:Medial_border_of_scapula] subset: human_reference_atlas synonym: "margo medialis (scapula)" EXACT [FMA:23242] synonym: "margo medialis scapulae" EXACT LATIN [FMA:23242, FMA:TA] synonym: "medial border of the scapula" RELATED [Wikipedia:Medial_border_of_scapula] synonym: "medial margin of the scapula" RELATED [Wikipedia:Medial_border_of_scapula] synonym: "medial part of scapula" EXACT [FMA:23242] synonym: "vertebral border" RELATED [Wikipedia:Medial_border_of_scapula] synonym: "vertebral border of scapula" EXACT [FMA:23242] synonym: "vertebral border of the scapula" RELATED [Wikipedia:Medial_border_of_scapula] xref: EMAPA:25127 xref: FMA:23242 xref: SCTID:368187009 xref: Wikipedia:Medial_border_of_scapula is_a: UBERON:0007171 {source="EMAPA-modified"} ! border of scapula relationship: has_developmental_contribution_from UBERON:0002329 {source="PMID:20136669"} ! somite property_value: editor_note "consider merging with UBERON:1500000 scapular blade, depending on https://github.com/obophenotype/uberon/issues/339. See also http://www.ncbi.nlm.nih.gov/pubmed/20136669" xsd:string property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007175 name: inferior angle of scapula namespace: uberon def: "An angle of the scapula formed by the union of the vertebral and axillary borders; its dorsal surface affords attachment to the Teres major and frequently to a few fibers of the Latissimus dorsi.[WP,unvetted]." [Wikipedia:Inferior_angle_of_scapula] subset: human_reference_atlas synonym: "angulus inferior (scapula)" EXACT [FMA:13315] synonym: "angulus inferior scapulae" EXACT LATIN [Wikipedia:Inferior_angle_of_scapula] xref: EMAPA:25128 xref: FMA:13315 xref: Wikipedia:Inferior_angle_of_scapula is_a: UBERON:0007172 {source="EMAPA-modified"} ! angle of scapula property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007177 name: lamina propria of mucosa of colon namespace: uberon def: "A lamina propria that is part of a colonic mucosa." [OBOL:automatic] subset: human_reference_atlas synonym: "colonic lamina propria" EXACT [FMA:15657] synonym: "lamina propria mucosae of colon" EXACT [FMA:15657] synonym: "lamina propria of colonic mucosa" EXACT [FMA:15657] synonym: "lamina propria of colonic mucous membrane" EXACT [FMA:15657] xref: EMAPA:27395 xref: FMA:15657 xref: MA:0003196 xref: SCTID:113284008 is_a: UBERON:0011189 ! lamina propria of large intestine intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0000317 ! colonic mucosa relationship: part_of UBERON:0000317 ! colonic mucosa property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007181 name: serosa of infundibulum of uterine tube namespace: uberon def: "A serous membrane that is part of a uterine tube infundibulum." [OBOL:automatic] synonym: "serosa of infundibulum of fallopian tube" EXACT [FMA:18324] synonym: "serosa of infundibulum of oviduct" EXACT [FMA:18324] xref: EMAPA:29903 xref: FMA:18324 is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum relationship: part_of UBERON:0003983 ! conus arteriosus relationship: part_of UBERON:0003984 ! uterine tube infundibulum [Term] id: UBERON:0007182 name: muscle layer of infundibulum of uterine tube namespace: uberon def: "A muscle layer that is part of a uterine tube infundibulum." [OBOL:automatic] synonym: "muscle layer of infundibulum of fallopian tube" EXACT [FMA:18336] synonym: "muscle layer of infundibulum of oviduct" EXACT [FMA:18336] synonym: "muscularis of infundibulum of uterine tube" EXACT [FMA:18336] xref: EMAPA:31264 xref: FMA:18336 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005983 ! heart layer is_a: UBERON:0006660 ! muscular coat intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0003984 ! uterine tube infundibulum relationship: part_of UBERON:0003983 ! conus arteriosus relationship: part_of UBERON:0003984 ! uterine tube infundibulum [Term] id: UBERON:0007188 name: mesothelium of serous pericardium namespace: uberon def: "A mesothelium that is part of a serous pericardium." [OBOL:automatic] synonym: "mesothelium of pericardium" EXACT [FMA:18149] synonym: "pericardial mesothelium" EXACT [FMA:18149] synonym: "serous pericardium mesothelium" EXACT [FMA:18149] xref: BTO:0003157 xref: EMAPA:16133 xref: FMA:18149 xref: SCTID:67300002 is_a: UBERON:0003388 ! mesothelium of pericardial cavity intersection_of: UBERON:0001136 ! mesothelium intersection_of: part_of UBERON:0002357 ! serous pericardium relationship: part_of UBERON:0002357 ! serous pericardium [Term] id: UBERON:0007195 name: stroma of bone marrow namespace: uberon def: "The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis." [Wikipedia:Bone_marrow#Stroma] synonym: "bone marrow stroma" EXACT [FMA:21426] xref: CALOHA:TS-0085 xref: FMA:21426 xref: Wikipedia:Bone_marrow#Stroma is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0003891 ! stroma is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0002371 ! bone marrow relationship: has_part CL:0002240 ! marrow fibroblast relationship: has_part UBERON:0000332 ! yellow bone marrow relationship: has_part UBERON:0003909 ! sinusoid relationship: part_of UBERON:0002371 ! bone marrow [Term] id: UBERON:0007196 name: tracheobronchial tree namespace: uberon alt_id: UBERON:0004102 def: "The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells." [Wikipedia:Tracheobronchial_tree] subset: human_reference_atlas subset: organ_slim subset: pheno_slim synonym: "arbor tracheobronchialis" EXACT LATIN [FMA:7393, FMA:TA] synonym: "tracheobronchial system" RELATED [HP:0005607] xref: FMA:7393 xref: NCIT:C117875 xref: SCTID:361384001 xref: Wikipedia:Tracheobronchial_tree is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000062 ! organ is_a: UBERON:0004119 ! endoderm-derived structure relationship: has_part UBERON:0002185 ! bronchus relationship: has_part UBERON:0003126 ! trachea relationship: has_part UBERON:0007592 {source="Wikipedia"} ! ciliated columnar epithelium relationship: part_of UBERON:0001558 ! lower respiratory tract property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007197 name: hermaphroditic organism namespace: uberon def: "Multicellular organism that can produce both male and female gametes." [http://orcid.org/0000-0001-9114-8737] synonym: "dioecious organism" RELATED [BILA:0000029] synonym: "hermaphrodite" RELATED [WBbt:0007849] xref: AAO:0010035 xref: BILA:0000029 xref: CARO:0000029 xref: HAO:0000029 xref: TADS:0000601 xref: WBbt:0007849 is_a: UBERON:0000468 ! multicellular organism [Term] id: UBERON:0007198 name: hermaphrodite anatomical structure namespace: uberon def: "An anatomical structure present only in hermaphrodites." [https://orcid.org/0000-0002-4422-9726] synonym: "hermaphrodite-specific" RELATED [WBbt:0005758] xref: AEO:0000177 xref: EHDAA2:0003177 xref: WBbt:0005758 is_a: UBERON:0014402 ! sex-specific anatomical structure intersection_of: UBERON:0014402 ! sex-specific anatomical structure intersection_of: part_of UBERON:0007197 ! hermaphroditic organism relationship: part_of UBERON:0007197 ! hermaphroditic organism [Term] id: UBERON:0007204 name: brachiocephalic vasculature namespace: uberon def: "The vasculature consisting of brachiocephalic arteries and veins." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0002049 ! vasculature [Term] id: UBERON:0007213 name: mesenchyme derived from head neural crest namespace: uberon def: "Mesenchyme that develops_from a cranial neural crest." [OBOL:automatic] subset: efo_slim subset: vertebrate_core synonym: "head mesenchyme from cranial neural crest" EXACT [] synonym: "head mesenchyme from neural crest" EXACT [EHDAA2:0000735] synonym: "head neural crest derived mesenchyme" EXACT [] xref: EFO:0003572 xref: EHDAA2:0000735 xref: EMAPA:16169 xref: EMAPA:16271 xref: EMAPA_RETIRED:16271 xref: TAO:0000787 xref: ZFA:0000787 is_a: UBERON:0005253 {source="ZFA"} ! head mesenchyme is_a: UBERON:0014387 ! mesenchyme derived from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0003099 ! cranial neural crest relationship: develops_from UBERON:0003099 ! cranial neural crest [Term] id: UBERON:0007214 name: mesenchyme derived from trunk neural crest namespace: uberon def: "Mesenchyme that develops_from a trunk neural crest." [OBOL:automatic] subset: vertebrate_core synonym: "trunk mesenchyme from neural crest" EXACT [EHDAA2:0002093] synonym: "trunk neural crest derived mesenchyme" EXACT [] xref: EHDAA2:0002093 xref: EMAPA:16182 xref: TAO:0000999 xref: ZFA:0000999 is_a: UBERON:0005256 ! trunk mesenchyme is_a: UBERON:0014387 ! mesenchyme derived from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0003083 ! trunk neural crest relationship: develops_from UBERON:0003083 ! trunk neural crest [Term] id: UBERON:0007220 name: late embryonic stage namespace: uberon def: "An embryo stage that covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching." [https://orcid.org/0000-0003-3308-6245] synonym: "embryo late (growth) stage" EXACT [MIAA:0000399] synonym: "embryo late growth stage" RELATED [BTO:0000449] synonym: "embryo late stage" RELATED [BTO:0000449] synonym: "fetal stage" NARROW SENSU [https://orcid.org/0000-0002-6601-2165] synonym: "fetus" NARROW [MIAA:0000399] synonym: "fetus stage" NARROW SENSU [https://orcid.org/0000-0002-6601-2165] xref: EV:0300011 xref: EVM:2990031 xref: FBdv:00005333 xref: FMA:63631 xref: MIAA:0000399 xref: MmusDv:0000031 xref: OGES:000023 xref: SCTID:367619004 is_a: UBERON:0000105 ! life cycle stage relationship: part_of UBERON:0000068 ! embryo stage relationship: preceded_by UBERON:0000111 ! organogenesis stage relationship: preceded_by UBERON:0004707 ! pharyngula stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/355" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/issues/565" xsd:anyURI [Term] id: UBERON:0007237 name: 1st arch mandibular component namespace: uberon synonym: "ventral mandibular arch" RELATED [VHOG:0000510] synonym: "ventral pharyngeal arch 1" EXACT [VHOG:0000510] synonym: "ventral visceral arch 1" RELATED [VHOG:0000510] xref: EHDAA2:0000031 xref: EHDAA:583 xref: EMAPA:16382 xref: VHOG:0000510 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004362 {source="EHDAA2"} ! pharyngeal arch 1 property_value: editor_note "relationship to Meckel's cartilage to be added" xsd:string property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000510", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0007238 name: 1st arch maxillary component namespace: uberon xref: EHDAA2:0000038 xref: EHDAA:595 xref: EMAPA:16388 xref: VHOG:0000511 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0004362 {source="EHDAA2"} ! pharyngeal arch 1 property_value: editor_note "relationship to palatoquadrate to be added" xsd:string property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000511", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0007239 name: tunica media of artery namespace: uberon def: "A tunica media that is part of a artery." [OBOL:automatic] synonym: "arterial media" EXACT [EV:0100029] synonym: "tunica media (arteriae)" EXACT [FMA:14273] xref: EMAPA:36294 xref: EV:0100029 xref: FMA:14273 xref: NCIT:C49321 xref: SCTID:84300001 xref: UMLS:C1710627 {source="ncithesaurus:Venous_System_Smooth_Muscle_Tissue"} is_a: UBERON:0002522 ! tunica media intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0001637 ! artery relationship: part_of UBERON:0000415 ! artery wall [Term] id: UBERON:0007240 name: tunica adventitia of artery namespace: uberon def: "A tunica adventitia that is part of a artery." [OBOL:automatic] synonym: "arterial adventitia" EXACT [EV:0100030] synonym: "tunica externa (adventitia)(arteriae)" EXACT [FMA:14274] xref: EMAPA:36295 xref: EV:0100030 xref: FMA:14274 xref: SCTID:113261001 is_a: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: part_of UBERON:0001637 ! artery relationship: has_part CL:1000306 {source="FMA"} ! fibroblast of tunica adventitia of artery relationship: part_of UBERON:0000415 ! artery wall [Term] id: UBERON:0007241 name: tunica adventitia of vein namespace: uberon def: "A tunica adventitia that is part of a vein." [OBOL:automatic] synonym: "tunica externa (adventitia)(venae)" EXACT [FMA:14355] synonym: "venous adventitia" EXACT [EV:0100034] xref: EMAPA:36310 xref: EV:0100034 xref: FMA:14355 xref: SCTID:13202006 is_a: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: UBERON:0005734 ! tunica adventitia of blood vessel intersection_of: part_of UBERON:0001638 ! vein relationship: part_of UBERON:0001638 ! vein [Term] id: UBERON:0007242 name: tunica intima of vein namespace: uberon def: "A tunica intima that is part of a vein." [OBOL:automatic] synonym: "tunica interna (intima)(venae)" EXACT [FMA:14353] synonym: "venous intima" EXACT [EV:0100032] xref: EMAPA:36308 xref: EV:0100032 xref: FMA:14353 xref: SCTID:2436009 is_a: UBERON:0002523 ! tunica intima is_a: UBERON:0004797 ! blood vessel layer intersection_of: UBERON:0002523 ! tunica intima intersection_of: part_of UBERON:0001638 ! vein relationship: part_of UBERON:0001638 ! vein [Term] id: UBERON:0007243 name: tunica media of vein namespace: uberon def: "A tunica media that is part of a vein." [OBOL:automatic] synonym: "tunica media (venae)" EXACT [FMA:14354] synonym: "venous media" EXACT [EV:0100033] xref: EMAPA:36309 xref: EV:0100033 xref: FMA:14354 xref: SCTID:42049001 is_a: UBERON:0002522 ! tunica media intersection_of: UBERON:0002522 ! tunica media intersection_of: part_of UBERON:0001638 ! vein relationship: part_of UBERON:0001638 ! vein [Term] id: UBERON:0007245 name: nuclear complex of neuraxis namespace: uberon def: "Gray matter of the central nervous system which is a collection of clustered nuclei." [http://orcid.org/0000-0002-6601-2165] synonym: "cluster of neural nuclei" RELATED [] synonym: "neural nuclei" RELATED [] synonym: "nuclear complex" RELATED [] xref: FMA:256381 xref: FMA:84059 is_a: UBERON:0002020 ! gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: composed_primarily_of UBERON:0000125 ! neural nucleus relationship: composed_primarily_of UBERON:0000125 ! neural nucleus [Term] id: UBERON:0007247 name: nucleus of superior olivary complex namespace: uberon def: "Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: pheno_slim synonym: "superior olivary complex nucleus" EXACT [FMA:72246] xref: FMA:72246 xref: SCTID:369024009 is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002128 ! superior olivary complex relationship: part_of UBERON:0002128 ! superior olivary complex property_value: IAO:0000232 "this class exists largely for consistency with the FMA. It is defined trivially with respect to the SOC. The class may be removed in future." xsd:string [Term] id: UBERON:0007267 name: trachea pre-cartilage rings namespace: uberon def: "A pre-cartilage condensation that is part of a trachea." [OBOL:automatic] xref: EHDAA2:0002070 xref: EHDAA:7082 is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0009505 ! mesenchyme of trachea intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0009505 {source="EHDAA2"} ! mesenchyme of trachea [Term] id: UBERON:0007269 name: pectoral appendage musculature namespace: uberon def: "Any collection of muscles that is part of a pectoral appendage." [OBOL:automatic] subset: efo_slim synonym: "pectoral fin muscle" NARROW [ZFA:0000563] synonym: "pectoral fin musculature" NARROW SENSU [ZFA:0000563] xref: EFO:0003540 xref: TAO:0000563 xref: ZFA:0000563 is_a: UBERON:0007271 ! appendage musculature is_a: UBERON:0014793 ! musculature of pectoral complex intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0004710 ! pectoral appendage relationship: part_of UBERON:0004710 ! pectoral appendage property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0007270 name: pelvic appendage musculature namespace: uberon def: "Any collection of muscles that is part of a pelvic appendage." [OBOL:automatic] synonym: "pelvic fin musculature" NARROW SENSU [ZFA:0000258] xref: TAO:0000258 xref: ZFA:0000258 is_a: UBERON:0007271 ! appendage musculature is_a: UBERON:0014792 ! musculature of pelvic complex intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0004709 ! pelvic appendage relationship: part_of UBERON:0004709 ! pelvic appendage property_value: editor_note "currently defined by location rather than attachment" xsd:string property_value: UBPROP:0000001 "Musculature that is part of the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000258", ontology="TAO", source="TAO:curator"} [Term] id: UBERON:0007271 name: appendage musculature namespace: uberon def: "Any collection of muscles that is part of an appendage." [OBOL:automatic] synonym: "fin musculature" NARROW SENSU [ZFA:0000207] xref: TAO:0000207 xref: ZFA:0000207 is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0000026 ! appendage relationship: part_of UBERON:0000026 ! appendage property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0007272 name: pectoral appendage skeleton namespace: uberon def: "Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle." [VSAO:0005000, VSAO:NI] synonym: "cheiropterygium" RELATED [VSAO:0005000, VSAO:NI] xref: VSAO:0005000 is_a: UBERON:0011582 ! paired limb/fin skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0004710 ! pectoral appendage relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0004710 {source="VSAO"} ! pectoral appendage relationship: skeleton_of UBERON:0004710 ! pectoral appendage property_value: RO:0002475 UBERON:0007273 [Term] id: UBERON:0007273 name: pelvic appendage skeleton namespace: uberon def: "The collection of all skeletal elements in a pelvic appendage region." [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0011582 ! paired limb/fin skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0004709 ! pelvic appendage relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0004709 {source="VSAO"} ! pelvic appendage relationship: skeleton_of UBERON:0004709 ! pelvic appendage [Term] id: UBERON:0007277 name: presumptive hindbrain namespace: uberon def: "The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure." [Wikipedia:Rhombencephalon] subset: efo_slim synonym: "embryonic rhombencephalon" RELATED [CALOHA:TS-2118] synonym: "future hindbrain" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "presumptive rhombencephalon" EXACT [ZFA:0000569] synonym: "rhombencephalon" RELATED [EHDAA2:0001630] xref: BAMS:HB xref: CALOHA:TS-2118 xref: EFO:0003440 xref: EHDAA2:0001630 xref: FMA:295640 xref: TAO:0000569 xref: Wikipedia:Rhombencephalon xref: ZFA:0000569 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0002028 ! hindbrain relationship: develops_from UBERON:0003076 {source="XAO-abduced"} ! posterior neural tube relationship: has_developmental_contribution_from UBERON:0003852 {source="cjm"} ! rhombencephalon neural crest relationship: has_potential_to_develop_into UBERON:0002028 ! hindbrain relationship: part_of UBERON:0006238 ! future brain property_value: editor_note "TODO - unify naming conventions" xsd:string property_value: UBPROP:0000001 "The embryonic rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. Rhombomeres Rh7-Rh4 form the myelencephalon that will give the medulla oblongata. Rhombomeres Rh3-Rh1 form the metencephalon that will form the pons and the cerebellum[NPX:PDR]." xsd:string {source="NPX:PDR"} [Term] id: UBERON:0007278 name: presumptive sinus venosus namespace: uberon def: "Portion of tissue that is part of the heart tube and will become the sinus venosus." [ZFA:0001722] xref: TAO:0002234 xref: ZFA:0001722 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0002063 ! sinus venosus relationship: has_potential_to_develop_into UBERON:0002063 ! sinus venosus relationship: part_of UBERON:0004141 {source="ZFA"} ! heart tube [Term] id: UBERON:0007280 name: presumptive endocardium namespace: uberon def: "A presumptive structure that has the potential to develop into a endocardium." [OBOL:automatic] xref: TAO:0002233 xref: ZFA:0001724 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0002165 ! endocardium relationship: develops_from UBERON:0003084 ! heart primordium relationship: has_potential_to_develop_into UBERON:0002165 ! endocardium relationship: part_of UBERON:0005498 ! primitive heart tube property_value: UBPROP:0000001 "Portion of tissue that is part of the heart tube and will become the endocardium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002233", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0007281 name: presumptive midbrain hindbrain boundary namespace: uberon def: "Embryonic structure that gives rise to the midbrain hindbrain boundary." [ZFA:0001187] subset: efo_slim synonym: "presumptive MHB" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "presumptive midbrain-hindbrain boundary" EXACT [ZFA:0001187] xref: EFO:0003446 xref: TAO:0001187 xref: XAO:0004086 xref: ZFA:0001187 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0003052 ! midbrain-hindbrain boundary relationship: has_potential_to_develop_into UBERON:0003052 ! midbrain-hindbrain boundary relationship: part_of UBERON:0006238 {source="ZFA"} ! future brain [Term] id: UBERON:0007282 name: presumptive segmental plate namespace: uberon def: "A presumptive structure that has the potential to develop into a presomitic mesoderm." [OBOL:automatic] subset: efo_slim synonym: "presumptive segmental plates" RELATED PLURAL [ZFA:0000053] xref: EFO:0003421 xref: TAO:0000053 xref: ZFA:0000053 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0003059 ! presomitic mesoderm relationship: develops_from UBERON:0009618 {consistent_with="https://github.com/obophenotype/uberon/wiki/The-neural-crest", source="EDHAA2"} ! trunk paraxial mesoderm relationship: has_potential_to_develop_into UBERON:0003059 ! presomitic mesoderm [Term] id: UBERON:0007284 name: presumptive neural plate namespace: uberon def: "A presumptive structure that has the potential to develop into a neural plate." [OBOL:automatic] subset: efo_slim synonym: "prospective neuroectoderm" EXACT [ZFA:0000063] synonym: "prospective vegetal ectoderm" EXACT [ZFA:0000063] xref: EFO:0003424 xref: TAO:0000063 xref: ZFA:0000063 is_a: UBERON:0016879 ! future central nervous system intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0003075 ! neural plate relationship: develops_from UBERON:0002346 ! neurectoderm relationship: has_potential_to_develop_into UBERON:0003075 ! neural plate relationship: part_of UBERON:0004734 ! gastrula property_value: editor_note "consider merging" xsd:string property_value: UBPROP:0000001 "Region of the gastrula which gives rise to the neural plate.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000063", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0007285 name: presumptive paraxial mesoderm namespace: uberon def: "The part of the blastula that has the potential to develop into a paraxial mesoderm." [https://github.com/obophenotype/uberon/issues/1277, UBERON:cjm] subset: efo_slim synonym: "future paraxial mesenchyme" EXACT [UBERON:cjm] synonym: "future paraxial mesoderm" EXACT [] xref: EFO:0003443 xref: TAO:0000591 xref: XAO:0004134 xref: ZFA:0000591 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 {source="https://github.com/obophenotype/uberon/issues/1277"} ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0003077 {source="https://github.com/obophenotype/uberon/issues/1277"} ! paraxial mesoderm intersection_of: part_of UBERON:0000307 {source="https://github.com/obophenotype/uberon/issues/1277"} ! blastula relationship: has_potential_to_develop_into UBERON:0003077 ! paraxial mesoderm relationship: part_of UBERON:0000307 ! blastula [Term] id: UBERON:0007288 name: presumptive forebrain midbrain boundary namespace: uberon def: "A presumptive structure that has the potential to develop into a forebrain-midbrain boundary." [OBOL:automatic] subset: efo_slim xref: EFO:0003463 xref: TAO:0001368 xref: ZFA:0001368 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0005075 ! forebrain-midbrain boundary relationship: has_potential_to_develop_into UBERON:0005075 ! forebrain-midbrain boundary relationship: part_of UBERON:0006238 ! future brain [Term] id: UBERON:0007297 name: presumptive pronephric mesoderm namespace: uberon def: "A presumptive structure that has the potential to develop into a pronephric mesoderm." [OBOL:automatic] subset: efo_slim synonym: "nephron primordium" EXACT [ZFA:0001070] xref: EFO:0003619 xref: TAO:0001070 xref: ZFA:0001070 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0005721 ! pronephric mesoderm relationship: has_potential_to_develop_into UBERON:0005721 ! pronephric mesoderm [Term] id: UBERON:0007300 name: pectoral appendage blood vessel namespace: uberon def: "A blood vessel that is part of a pectoral appendage." [OBOL:automatic] synonym: "pectoral fin blood vessel" NARROW SENSU [ZFA:0005301] xref: TAO:0005301 xref: ZFA:0005301 is_a: UBERON:0007301 ! appendage blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0004710 ! pectoral appendage relationship: part_of UBERON:0004710 ! pectoral appendage [Term] id: UBERON:0007301 name: appendage blood vessel namespace: uberon def: "A blood vessel that is part of a limb/fin." [OBOL:automatic] synonym: "fin blood vessel" NARROW SENSU [ZFA:0005299] synonym: "limb blood vessel" NARROW SENSU [] xref: TAO:0005299 xref: ZFA:0005299 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0000026 ! appendage relationship: part_of UBERON:0007304 ! appendage vasculature [Term] id: UBERON:0007302 name: pectoral appendage vasculature namespace: uberon def: "A vasculature that is part of a pectoral appendage." [OBOL:automatic] synonym: "pectoral fin vasculature" NARROW SENSU [ZFA:0005096] xref: TAO:0005096 xref: ZFA:0005096 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0007304 ! appendage vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0004710 ! pectoral appendage relationship: part_of UBERON:0004710 ! pectoral appendage [Term] id: UBERON:0007303 name: pharyngeal vasculature namespace: uberon def: "A vasculature that is part of a chordate pharynx." [OBOL:automatic] synonym: "branchial vasculature" EXACT [ZFA:0005003] xref: TAO:0005003 xref: ZFA:0005003 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0001042 ! chordate pharynx [Term] id: UBERON:0007304 name: appendage vasculature namespace: uberon def: "A vasculature that is part of a limb/fin." [OBOL:automatic] synonym: "fin vasculature" NARROW SENSU [ZFA:0005095] xref: TAO:0005095 xref: ZFA:0005095 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000026 ! appendage relationship: part_of UBERON:0000026 ! appendage [Term] id: UBERON:0007318 name: saphenous vein namespace: uberon def: "Either of two main superficial veins of the leg, one larger than the other, that begin at the foot." [BTO:0001808] xref: BTO:0001808 xref: CALOHA:TS-0893 xref: EMAPA:37186 {source="MA:th"} xref: MA:0002215 xref: MESH:D012501 xref: NCIT:C33511 xref: UMLS:C0036186 {source="ncithesaurus:Saphenous_Vein"} is_a: UBERON:0004261 ! lower leg blood vessel is_a: UBERON:0035550 ! superficial vein [Term] id: UBERON:0007324 name: pancreatic lobule namespace: uberon def: "A dense accumulation of exocrine glands in the pancreas often surrounding islets of Langerhans." [ISBN:0123813611] subset: human_reference_atlas synonym: "lobulus pancreaticus" EXACT [FMA:16012] synonym: "pancreas lobe" EXACT [MA:0000721] synonym: "pancreatic lobule" EXACT [FMA:16012] xref: EMAPA:37710 {source="MA:th"} xref: FMA:16012 xref: MA:0000721 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000064 ! organ part is_a: UBERON:0004119 ! endoderm-derived structure relationship: has_part UBERON:0001263 ! pancreatic acinus relationship: has_part UBERON:0014719 ! intralobular duct relationship: part_of UBERON:0000017 ! exocrine pancreas property_value: editor_note "TODO - check" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In mice many lobules lack islets, in contrast to other mammals including humans" xsd:string [Term] id: UBERON:0007329 name: pancreatic duct namespace: uberon def: "A duct that collects and carries secretions of the exocrine pancreas to the intestine." [GOC:cvs, GOC:ymb, https://github.com/obophenotype/uberon/issues/1250, https://orcid.org/0000-0002-2244-7917, https://orcid.org/0000-0002-6601-2165, https://orcid.org/0000-0002-9900-7880, Wikipedia:Pancreatic_duct] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "duct of pancreas" EXACT [OBOL:accepted] synonym: "ductus pancreaticus" RELATED LATIN [Wikipedia:Pancreatic_duct] synonym: "pancreas duct" EXACT [OBOL:accepted] xref: EHDAA:9194 xref: EMAPA:32952 xref: FMA:10419 xref: MA:0000124 xref: MESH:D010183 xref: SCTID:181278006 xref: TAO:0001372 xref: VHOG:0000254 xref: Wikipedia:Pancreatic_duct xref: ZFA:0001372 is_a: UBERON:0003928 {source="ZFA"} ! digestive system duct is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000058 ! duct intersection_of: connected_to UBERON:0000160 ! intestine intersection_of: part_of UBERON:0001264 ! pancreas relationship: connected_to UBERON:0000160 ! intestine relationship: contributes_to_morphology_of UBERON:0000017 ! exocrine pancreas relationship: develops_from UBERON:0003922 ! pancreatic epithelial bud relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000017 {source="MA"} ! exocrine pancreas property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/15/Gray1100.png" xsd:anyURI property_value: IAO:0000232 "this class groups together accessory (dorsal) and main (ventral) pancreatic ducts" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Duct connecting the pancreas with the intestine. [Dorian_AF, Elsevier's_encyclopaedic_dictionary_of_medicine, Part_B:_Anatomy_(1988)_Amsterdam_etc.:_Elsevier][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000254", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "These data show that ducts within the zebrafish pancreas originally arise in situ from isolated progenitor cells rather than arising from reiterative branching of the pancreatic epithelium. This process of pancreatic duct formation in zebrafish may be analogous to the mechanism of duct formation in the mammalian mammary and salivary glands. (...) A related mechanism of duct formation has also been proposed to occur within the mammalian pancreatic epithelium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000254", ontology="VHOG", source="DOI:10.1016/j.ydbio.2005.04.035 Yee NS, Lorent K, Pack M, Exocrine pancreas development in zebrafish. Developmental Biology (2005)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "in EHDAA2, the dorsal and ventral ducts are classified as epithelial sacs - review after overhaul of duct/epithelia terms" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0007367 name: surface of tongue namespace: uberon def: "An anatomical surface that is part of a tongue." [OBOL:automatic] synonym: "tongue surface" EXACT [FMA:54647] xref: FMA:54647 xref: SCTID:314870004 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0036215 ! anatomical surface region intersection_of: UBERON:0036215 ! anatomical surface region intersection_of: bounding_layer_of UBERON:0001723 ! tongue relationship: bounding_layer_of UBERON:0001723 ! tongue relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0007371 name: superior surface of tongue namespace: uberon def: "The upper (superior) side of the tongue." [http://orcid.org/0000-0002-6601-2165] synonym: "dorsal surface of tongue" EXACT [FMA:54646] xref: FMA:54646 is_a: UBERON:0007367 ! surface of tongue intersection_of: UBERON:0007367 ! surface of tongue intersection_of: in_dorsal_side_of UBERON:0001723 ! tongue relationship: in_dorsal_side_of UBERON:0001723 ! tongue property_value: editor_note "check superior/dorsal" xsd:string [Term] id: UBERON:0007375 name: roof of mouth namespace: uberon def: "A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity. In mammals this is the combination of the primary palate (premaxilla) and the secondary palate. In early tetrapods it consists of the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "palate" RELATED [] synonym: "palatum" RELATED INCONSISTENT [] synonym: "primary or secondary palate" RELATED [] synonym: "roof of buccal cavity" EXACT [] synonym: "roof of oral cavity" EXACT [] xref: CALOHA:TS-2212 xref: Wikipedia:Palate is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0000033 ! head property_value: editor_note "check subclasses to verify if they refer to a multi-tissue structure or a subdivision of the skeleton" xsd:string [Term] id: UBERON:0007376 name: outer epithelium namespace: uberon def: "The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]." [GO:0008544] subset: grouping_class synonym: "epidermis" EXACT [GO:0008544] synonym: "epidermis (sensu Metazoa)" EXACT [] synonym: "hypoderm" RELATED INCONSISTENT [BTO:0000313] synonym: "hypodermis" RELATED INCONSISTENT [GO:0008544, WBbt:0005733] synonym: "outer epidermal layer" EXACT [] synonym: "outer epithelial layer" EXACT [] xref: BSA:0000073 xref: BTO:0000313 xref: FBbt:00004993 xref: HAO:0000298 xref: TADS:0000109 xref: WBbt:0005733 xref: Wikipedia:Epidermis_(zoology) is_a: UBERON:0003102 ! surface structure is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: bounding_layer_of UBERON:0000468 ! multicellular organism intersection_of: develops_from UBERON:0007383 ! enveloping layer of ectoderm relationship: bounding_layer_of UBERON:0000468 ! multicellular organism relationship: develops_from UBERON:0007383 ! enveloping layer of ectoderm property_value: editor_note "this grouping class exists primarily to align with GO - see GO:0008544." xsd:string [Term] id: UBERON:0007383 name: enveloping layer of ectoderm namespace: uberon def: "Outermost layer of cells surrounding the embryo." [http://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "enveloping layer" EXACT [ZFIN:ZDB-PUB-961014-576] synonym: "EVL" EXACT [ZFA:0000086] xref: EFO:0003425 xref: TAO:0000086 xref: ZFA:0000086 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium relationship: bounding_layer_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0000076 ! external ectoderm property_value: UBPROP:0000001 "Outermost monolayer of cells surrounding the embryo that become very flattened in the blastula and give rise to the periderm. Sometimes used synonymously with periderm. Kimmel et al, 1995.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000086", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000002 "relationship loss: develops_from superficial blastomere (TAO:0001484)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000086", ontology="TAO"} property_value: UBPROP:0000008 "Originally this tissue is one cell layer thick but in most vertebrates it soon becomes a two layered structure. The outer layer gives rise to the periderm." xsd:string [Term] id: UBERON:0007389 name: paired limb/fin cartilage namespace: uberon def: "A cartilage tissue that is part of a paired limb or fin." [http://orcid.org/0000-0002-6601-2165] subset: homology_grouping xref: TAO:0001543 xref: ZFA:0001543 is_a: UBERON:0002418 ! cartilage tissue intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0004708 ! paired limb/fin relationship: part_of UBERON:0002091 ! appendicular skeleton relationship: part_of UBERON:0004708 ! paired limb/fin property_value: UBPROP:0000001 "Cartilage which is part of one of the paired fins.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001543", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0007390 name: pectoral appendage cartilage tissue namespace: uberon def: "A cartilage tissue that is part of a pectoral appendage." [OBOL:automatic] synonym: "pectoral fin cartilage" RELATED [TAO:0000257] xref: TAO:0000257 xref: ZFA:0000257 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0007389 ! paired limb/fin cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0004710 ! pectoral appendage relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0007272 ! pectoral appendage skeleton property_value: UBPROP:0000001 "Cartilage which is part of the pectoral fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000257", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0007391 name: pelvic appendage cartilage tissue namespace: uberon def: "A cartilage tissue that is part of a pelvic appendage." [OBOL:automatic] synonym: "pelvic fin cartilage" RELATED [TAO:0001459] xref: TAO:0001459 xref: ZFA:0001459 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0007389 ! paired limb/fin cartilage intersection_of: UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0004709 ! pelvic appendage relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0007273 ! pelvic appendage skeleton property_value: UBPROP:0000001 "Cartilage which is part of the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001459", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0007414 name: nucleus of midbrain tegmentum namespace: uberon alt_id: UBERON:0012277 def: "A nucleus of brain that spans a midbrain tegmentum." [OBOL:automatic] synonym: "tegmental nuclei" EXACT PLURAL [] synonym: "tegmental nucleus" EXACT [ZFA:0005577] xref: FMA:258768 xref: ZFA:0005577 is_a: UBERON:0000125 ! neural nucleus intersection_of: UBERON:0000125 ! neural nucleus intersection_of: overlaps UBERON:0001943 ! midbrain tegmentum relationship: overlaps UBERON:0001943 ! midbrain tegmentum property_value: IAO:0000232 "this class groups together any nuclei in the tegmentum region, possibly including disparate structures across species" xsd:string [Term] id: UBERON:0007473 name: lumen of epithelial sac namespace: uberon def: "The space within an epithelial sphere." [AEO:JB] synonym: "cavity of vesicle" EXACT [AEO:0000079] xref: AEO:0000079 is_a: UBERON:0012467 ! enclosed anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0007499 ! epithelial sac relationship: luminal_space_of UBERON:0007499 ! epithelial sac relationship: part_of UBERON:0007499 ! epithelial sac [Term] id: UBERON:0007475 name: matrix-based tissue namespace: uberon def: "A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified." [AEO:JB] xref: AEO:0000081 xref: EHDAA2:0003081 is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: composed_primarily_of GO:0031012 ! extracellular matrix relationship: composed_primarily_of GO:0031012 ! extracellular matrix [Term] id: UBERON:0007490 name: keratin-based acellular structure namespace: uberon def: "Acellular anatomical structure whose predominant constituent is keratin." [AEO:JB] synonym: "keratin-based structure" RELATED [EHDAA2:0003099] xref: AEO:0000099 xref: EHDAA2:0003099 is_a: UBERON:0000476 ! acellular anatomical structure intersection_of: UBERON:0000476 ! acellular anatomical structure intersection_of: composed_primarily_of GO:0045095 ! keratin filament relationship: composed_primarily_of GO:0045095 ! keratin filament relationship: has_quality PATO:0002507 ! keratinous property_value: editor_note "should all structures composed primarily of keratin be classified here? At what stage of cornification are keratin-filled cells no longer considered cells" xsd:string [Term] id: UBERON:0007499 name: epithelial sac namespace: uberon def: "An epithelial tube that is open at one end only." [AEO:JB, UBERONREF:0000001] xref: AEO:0000115 xref: EHDAA2:0003115 is_a: UBERON:0003914 {source="AEO"} ! epithelial tube is_a: UBERON:0009856 ! sac intersection_of: UBERON:0000483 ! epithelium intersection_of: has_quality PATO:0001987 ! saccular [Term] id: UBERON:0007500 name: epithelial tube open at both ends namespace: uberon def: "An epithelial tube open at both ends that allows fluid flow." [AEO:JB, UBERONREF:0000001] xref: AEO_RETIRED:0000116 xref: RETIRED_EHDAA2:0003116 is_a: UBERON:0003914 {source="AEO"} ! epithelial tube [Term] id: UBERON:0007501 name: arborizing epithelial duct system namespace: uberon def: "A collection of connected epithelial tubes with a single portal." [AEO:JB, UBERONREF:0000001] synonym: "arborising epithelial duct system" EXACT [AEO:0000117] xref: AEO:0000117 xref: EHDAA2:0003117 is_a: UBERON:0007499 {source="AEO"} ! epithelial sac relationship: has_part UBERON:0003914 {source="AEO"} ! epithelial tube [Term] id: UBERON:0007503 name: epithelial vesicle namespace: uberon def: "A closed epithelium with a lumen." [AEO:JB] xref: AEO:0000119 xref: EHDAA2:0003119 is_a: UBERON:0000483 {source="AEO"} ! epithelium [Term] id: UBERON:0007521 name: smooth muscle sphincter namespace: uberon def: "A ring of smooth muscle cells whose contraction closes the opening of the ring." [AEO:JB] xref: AEO:0000143 xref: EHDAA2:0003143 xref: SCTID:362915001 is_a: UBERON:0004590 ! sphincter muscle intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: has_part CL:0000192 ! smooth muscle cell relationship: composed_primarily_of UBERON:0001135 ! smooth muscle tissue relationship: has_part CL:0000192 ! smooth muscle cell [Term] id: UBERON:0007522 name: striated muscle sphincter namespace: uberon def: "A ring of striated muscle cells whose contraction closes the opening of the ring." [AEO:JB] xref: AEO:0000144 xref: EHDAA2:0003144 is_a: UBERON:0004590 ! sphincter muscle intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: has_part CL:0000737 ! striated muscle cell relationship: composed_primarily_of UBERON:0002036 ! striated muscle tissue relationship: has_part CL:0000737 ! striated muscle cell [Term] id: UBERON:0007524 name: dense mesenchyme tissue namespace: uberon def: "Mesenchyme with little extracellular matrix." [AEO:JB] xref: AEO:0000146 xref: EHDAA2:0003146 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 {source="AEO"} ! mesenchyme relationship: has_part CL:0000057 {source="AEO"} ! fibroblast [Term] id: UBERON:0007529 name: loose mesenchyme tissue namespace: uberon def: "Mesenchyme whose cells are embedded in obvious amounts of extracellular matrix." [AEO:JB] xref: AEO:0000151 xref: EHDAA2:0003151 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 {source="AEO"} ! mesenchyme relationship: has_part CL:0000057 {source="AEO"} ! fibroblast relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell [Term] id: UBERON:0007530 name: migrating mesenchyme population namespace: uberon def: "Mesenchymal cells that are migrating." [AEO:JB] xref: AEO:0000152 xref: EHDAA2:0003152 is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: participates_in GO:0016477 ! cell migration relationship: participates_in GO:0016477 ! cell migration property_value: editor_note "this class will be an important part of the NC reorganization" xsd:string [Term] id: UBERON:0007589 name: ciliated columnar oviduct epithelium namespace: uberon def: "A ciliated columnar epithelium that is part of a oviduct." [OBOL:automatic] subset: human_reference_atlas synonym: "epithelium of uterine tube" RELATED [FMA:62016] synonym: "uterine tube epithelium" RELATED [FMA:62016] xref: FMA:62016 xref: MA:0001719 is_a: UBERON:0004804 {source="MA"} ! oviduct epithelium is_a: UBERON:0007592 {source="FMA"} ! ciliated columnar epithelium intersection_of: UBERON:0007592 ! ciliated columnar epithelium intersection_of: part_of UBERON:0000993 ! oviduct property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "in FMA, epithelium of uterine tube is a subclass of ciliated columnar epithelium. MA introduces subtypes: ciliated columnar and cuboidal. We map the FMA type according to its relationships, not its label" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0007590 name: cuboidal oviduct epithelium namespace: uberon def: "A cuboidal epithelium that is part of a oviduct." [OBOL:automatic] subset: human_reference_atlas xref: MA:0001720 is_a: UBERON:0004804 {source="MA"} ! oviduct epithelium is_a: UBERON:0010077 ! cuboidal epithelium intersection_of: UBERON:0010077 ! cuboidal epithelium intersection_of: part_of UBERON:0000993 ! oviduct property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007592 name: ciliated columnar epithelium namespace: uberon def: "Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA]." [FMA:64798] xref: FMA:64798 is_a: UBERON:0000485 {source="FMA"} ! simple columnar epithelium is_a: UBERON:0007601 ! ciliated epithelium intersection_of: UBERON:0000485 ! simple columnar epithelium intersection_of: has_part CL:0000067 ! ciliated epithelial cell property_value: UBPROP:0000008 "In humans, Ciliated columnar epithelial cells are found mainly in the tracheal and bronchial regions of the pulmonary system and also in the fallopian tubes of the female reproductive system" xsd:string property_value: UBPROP:0000009 "Ciliated columnar epithelium in the pulmonary system is interspersed with goblet cells that secrete mucous to form a mucosal layer apical to the epithelial layer. The rowing-like action of epithelial cilia work in tandem with goblet cells to propel mucus away from the lungs, preventing particulate matter from causing infection[http://www.bio.davidson.edu/people/kabernd/berndcv/lab/epithelialinfoweb/ciliated%20columnar%20epithelium.html]" xsd:string [Term] id: UBERON:0007601 name: ciliated epithelium namespace: uberon def: "Epithelium bearing vibratile cilia on the free surface." [http://medical-dictionary.thefreedictionary.com/ciliated+epithelium] is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: has_part CL:0000067 ! ciliated epithelial cell relationship: has_part CL:0000067 ! ciliated epithelial cell [Term] id: UBERON:0007616 name: layer of synovial tissue namespace: uberon def: "A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]." [BTO:0001338, http://www.britannica.com/EBchecked/topic/578563/synovial-tissue] synonym: "stratum synoviale" NARROW [FMA:TA] synonym: "synovial layer" NARROW [FMA:66762] synonym: "synovial membrane" NARROW [FMA:66762] synonym: "synovial tissue" RELATED [BTO:0001338] synonym: "synovium" EXACT [CALOHA:TS-0998] xref: BTO:0001338 xref: CALOHA:TS-0998 xref: FMA:66762 is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: produces UBERON:0001090 ! synovial fluid relationship: composed_primarily_of UBERON:0002384 {source="BTO"} ! connective tissue relationship: produces UBERON:0001090 ! synovial fluid [Term] id: UBERON:0007617 name: synovial cavity of joint namespace: uberon def: "An anatomical cavity that surrounded_by a synovial joint." [OBOL:automatic] subset: human_reference_atlas synonym: "articular cavity (synovial joint)" EXACT [FMA:11356] synonym: "cavitas articularis (junctura synovialis)" EXACT [FMA:11356] synonym: "cavity of synovial joint" EXACT [FMA:11356] synonym: "joint cavity" RELATED [FMA:11356] synonym: "synovial cavity" RELATED [FMA:11356] xref: FMA:11356 is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002217 ! synovial joint relationship: luminal_space_of UBERON:0002217 ! synovial joint relationship: part_of UBERON:0002217 ! synovial joint property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007618 name: synovial cavity of hip joint namespace: uberon def: "A synovial cavity of joint that is part of a hip joint." [OBOL:automatic] xref: EMAPA:19021 xref: FMA:9701 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0007617 ! synovial cavity of joint intersection_of: UBERON:0007617 ! synovial cavity of joint intersection_of: part_of UBERON:0001486 ! hip joint relationship: part_of UBERON:0001486 {source="FMA"} ! hip joint [Term] id: UBERON:0007625 name: pigment epithelium of eye namespace: uberon def: "Epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules." [MP:0005200] subset: pheno_slim synonym: "eye pigment epithelium" RELATED [MESH:A09.371.670] xref: GAID:907 xref: MESH:D010857 is_a: UBERON:0019304 ! sensory organ epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000970 ! eye relationship: part_of UBERON:0000970 ! eye [Term] id: UBERON:0007635 name: nucleus of medulla oblongata namespace: uberon def: "A neural nucleus that is part of a medulla oblongata." [OBOL:automatic] xref: FMA:258772 xref: SCTID:304943004 is_a: UBERON:0006331 ! brainstem nucleus is_a: UBERON:0009662 ! hindbrain nucleus intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0001896 ! medulla oblongata relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0007641 name: trigeminal nuclear complex namespace: uberon def: "The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]." [Wikipedia:Trigeminal_nerve_nuclei] synonym: "nuclei trigemini" RELATED LATIN [Wikipedia:Trigeminal_nerve_nuclei] synonym: "trigeminal nuclei" EXACT [FMA:71248] xref: BIRNLEX:4096 xref: BM:V xref: CALOHA:TS-2077 xref: DHBA:266441713 xref: FMA:71248 xref: HBA:9203 xref: neuronames:2021 xref: UMLS:C0040999 {source="BIRNLEX:4096"} xref: Wikipedia:Trigeminal_nerve_nuclei is_a: UBERON:0007245 {source="FMA"} ! nuclear complex of neuraxis relationship: extends_fibers_into UBERON:0001645 ! trigeminal nerve relationship: overlaps UBERON:0003023 {source="FMA"} ! pontine tegmentum relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/30/Gray696.png" xsd:anyURI property_value: UBPROP:0000012 "in MA and FMA this is part of the pons / pontime tegmentum. We weaken this to overlaps to avoid inconsistency. In NIF this is a composite structure spanning multiple regions, which is more appropriate." xsd:string {external_ontology="MA"} [Term] id: UBERON:0007645 name: future meninx namespace: uberon alt_id: UBERON:0004065 def: "A developing mesenchymal capsule that covers the developing brain and spinal cord and is the precursor of the meningeal cluster. In mammals this gives rise to the arachnoid mater, pia mater and dura mater. In cyclostomes and fishes, the future meninx gives rise to a single meningeal layer, the primitive meninx." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "meninx primitiva" RELATED [MP:0009726] synonym: "primary meninx" EXACT [EHDAA2:0004453] synonym: "primitive meninx" RELATED [] synonym: "primordial meninx" RELATED [] xref: EHDAA2:0004453 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0002360 ! meninx relationship: has_developmental_contribution_from UBERON:0007213 {source="ISBN:0073040584"} ! mesenchyme derived from head neural crest relationship: has_potential_to_develop_into UBERON:0002360 ! meninx relationship: part_of UBERON:0010743 {source="EHDAA2"} ! meningeal cluster property_value: editor_note "decide whether to treat the endo and ecto meninx as subtypes or parts of the future meninx" xsd:string property_value: UBPROP:0000001 "the outermost mesenchymal covering of the developing brain and spinal cord that is composed of tough fibrous connective tissue from which the arachnoid mater, pia mater and dura mater are formed[MP:0009726]d" xsd:string {source="MP:0009726"} [Term] id: UBERON:0007647 name: ectomeninx namespace: uberon alt_id: UBERON:0010115 def: "The outermost layer of the mesenchymal capsule that surrounds the developing brain, of mixed paraxial mesoderm and neural crest origin. The ectomeninx forms the dura mater (both inner layer and outer chondrogenic layer)." [ISBN:9781607950325] synonym: "future dura mater" EXACT [EHDAA2:0004317] xref: EHDAA2:0004317 is_a: UBERON:0007645 ! future meninx intersection_of: UBERON:0007645 ! future meninx intersection_of: has_potential_to_develop_into UBERON:0002363 ! dura mater relationship: develops_from UBERON:0009617 {source="ISBN:9781607950325"} ! head paraxial mesoderm relationship: has_potential_to_develop_into UBERON:0002363 ! dura mater [Term] id: UBERON:0007651 name: anatomical junction namespace: uberon def: "An anatomical structure that connects two structures." [http://code.google.com/p/caro2/issues/detail?id=15] subset: common_anatomy subset: upper_level synonym: "anatomical junction" EXACT [] synonym: "junction" BROAD [] xref: FMA:5898 xref: SCTID:91833003 is_a: UBERON:0000061 {source="FMA"} ! anatomical structure relationship: connects UBERON:0000061 {minCardinality="2"} ! anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0007652 name: esophageal sphincter namespace: uberon def: "A sphincter that is part of an esophagus." [http://orcid.org/0000-0002-6601-2165] xref: SCTID:277765007 is_a: UBERON:0003832 ! esophagus muscle is_a: UBERON:0004590 ! sphincter muscle intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0001043 ! esophagus property_value: editor_note "check for specific subtypes across species. Note mammals have upper and lower, but lower is really part of cardia and thus is not classified under here" xsd:string [Term] id: UBERON:0007684 name: uriniferous tubule namespace: uberon def: "Functional unit of the kidney that forms urine, consisting of two parts, the nephron and the collecting tubule." [ISBN:0073040584] xref: FMA:17691 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0006555 ! excretory tube relationship: has_part UBERON:0001232 ! collecting duct of renal tubule relationship: has_part UBERON:0001285 ! nephron [Term] id: UBERON:0007687 name: kidney field namespace: uberon def: "Region of the embryo into the area in which the kidney rudiment will develop." [DOI:10.1371/journal.pone.0099864, GO:0072004, GOC:mtg_kidney_jan10] synonym: "kidney anlage" RELATED [GOC:mtg_kidney_jan10] is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0006598 ! presumptive structure is_a: UBERON:0007688 ! anlage intersection_of: UBERON:0007688 ! anlage intersection_of: has_potential_to_develop_into UBERON:0002113 ! kidney relationship: has_potential_to_develop_into UBERON:0002113 ! kidney [Term] id: UBERON:0007688 name: anlage namespace: uberon def: "Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue." [FBbt:00005426, http://flybase.org/reports/FBrf0178740.html] subset: efo_slim synonym: "developmental field" EXACT [] synonym: "field" BROAD [] synonym: "future organ" RELATED [] synonym: "organ field" RELATED [] xref: AEO:0000170 xref: EFO:0001649 xref: EHDAA2:0003170 xref: FBbt:00005426 xref: Wikipedia:Anlage_(biology) is_a: UBERON:0000479 {source="FBbt"} ! tissue is_a: UBERON:0005423 {source="AEO", source="FBbt"} ! developing anatomical structure [Term] id: UBERON:0007690 name: early pharyngeal endoderm namespace: uberon def: "." [http://dev.biologists.org/content/128/22/4573.full] comment: relation conflict: ZFA vs EHDAA2. Note EHDAA2 term renamed to 'early PA endoderm' subset: efo_slim synonym: "early pharyngeal arch endoderm" EXACT [EHDAA2:0001457] synonym: "pharyngeal arch endoderm" RELATED [] synonym: "pharyngeal endoderm" RELATED [ZFA:0001104] synonym: "pharyngeal region endoderm" RELATED [EHDAA2:0001456] xref: EFO:0003626 xref: EHDAA2:0001457 xref: EHDAA:962 xref: EMAPA:32754 xref: FMA:293087 xref: TAO:0001104 xref: ZFA:0001104 is_a: UBERON:0003258 ! endoderm of foregut is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0009722 {source="cjm"} ! entire pharyngeal arch endoderm [Term] id: UBERON:0007691 name: gustatory pore namespace: uberon def: "The minute opening of a taste bud on the surface of the oral mucosa through which the gustatory hairs of the specialised neuroepithelial gustatory cells project." [http://www.mondofacto.com/facts/dictionary?gustatory+pore] synonym: "porus gustatorius" EXACT [http://www.mondofacto.com/facts/dictionary?gustatory+pore] synonym: "taste pore" EXACT [FMA:63589] xref: FMA:63589 xref: NCIT:C33738 xref: SCTID:368724008 xref: UMLS:C0226971 {source="ncithesaurus:Taste_Pore"} is_a: UBERON:0000161 {source="FMA"} ! orifice is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0001727 ! taste bud relationship: continuous_with UBERON:0000167 ! oral cavity relationship: part_of UBERON:0001727 {source="FMA"} ! taste bud property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/0/0e/Taste_bud.svg" xsd:anyURI [Term] id: UBERON:0007719 name: bone of reproductive organ namespace: uberon def: "A bone that is part of a reproductive organ." [https://github.com/obophenotype/uberon/issues/1158, OBOL:automatic] synonym: "baculum" NARROW [] synonym: "os penis/os clitoris" RELATED [] is_a: UBERON:0001474 ! bone element is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0003133 ! reproductive organ relationship: part_of UBERON:0003133 ! reproductive organ property_value: RO:0002161 NCBITaxon:9606 {source="Wikipedia"} [Term] id: UBERON:0007721 name: interphalangeal joint of pes namespace: uberon def: "The interphalangeal articulations of the foot (articulations of the phalanges) are ginglymoid joints, and each has a plantar and two collateral ligaments. The arrangement of these ligaments is similar to that in the metatarsophalangeal articulations: the Extensor tendons supply the places of dorsal ligaments." [Wikipedia:Interphalangeal_articulations_of_the_foot] subset: pheno_slim synonym: "foot interphalangeal joint" EXACT [MESH:A02.835.583.378.900] synonym: "hindlimb digit inter-phalangeal joint" EXACT [EMAPA:36337] synonym: "interphalangeal joint of foot" EXACT [FMA:35225] synonym: "interphalangeal joint of toe" NARROW SENSU [FMA:35225, NCBITaxon:9606] synonym: "toe joint" RELATED [MESH:A02.835.583.378.900] xref: EMAPA:36337 xref: FMA:35225 xref: MESH:D014033 xref: NCIT:C32867 xref: NCIT:C33789 xref: SCTID:182225005 xref: UMLS:C0040356 {source="ncithesaurus:Interphalangeal_Joint_of_the_Foot"} xref: Wikipedia:Interphalangeal_articulations_of_the_foot is_a: UBERON:0001487 ! pes joint is_a: UBERON:0006658 ! interphalangeal joint intersection_of: UBERON:0006658 ! interphalangeal joint intersection_of: part_of UBERON:0001466 ! pedal digit relationship: connects UBERON:0001449 {notes="two in series"} ! phalanx of pes relationship: connects UBERON:0001449 {cardinality="2"} ! phalanx of pes relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0007722 name: interphalangeal joint of manus namespace: uberon def: "The interphalangeal articulations of hand are hinge-joints of the phalanges of the hand. There are two sets (except in the thumb): 'proximal interphalangeal joints' (PIP), those between the first (also called proximal) and second (intermediate) phalanges 'distal interphalangeal joints' (DIP), those between the second and third (distal) phalanges A similar group of articulations also function in the toes." [Wikipedia:Interphalangeal_articulations_of_the_hand] subset: pheno_slim synonym: "articulationes digitorum manus" EXACT [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "articulationes interphalangeae manus" EXACT [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "articulations of the digits" RELATED [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "interphalangeal articulations of hand" RELATED [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "interphalangeal joint of finger" NARROW SENSU [FMA:35285, NCBITaxon:9606] synonym: "interphalangeal joint of hand" EXACT [FMA:35285] synonym: "interphalangeal joints of hand" RELATED [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "IP joint" RELATED [FMA:35285] xref: EMAPA:36336 xref: FMA:35285 xref: NCIT:C32868 xref: SCTID:303280009 xref: UMLS:C0016125 {source="ncithesaurus:Interphalangeal_Joint_of_the_Hand"} xref: Wikipedia:Interphalangeal_articulations_of_the_hand is_a: UBERON:0001489 ! manus joint is_a: UBERON:0006658 ! interphalangeal joint intersection_of: UBERON:0006658 ! interphalangeal joint intersection_of: part_of UBERON:0002389 ! manual digit relationship: connects UBERON:0001436 {notes="two in series"} ! phalanx of manus relationship: connects UBERON:0001436 {cardinality="2"} ! phalanx of manus relationship: part_of UBERON:0002389 ! manual digit property_value: editor_note "consider renaming: 'finger' is ambiguous as the term in some usages excludes the thumb (we include it)" xsd:string [Term] id: UBERON:0007723 name: interphalangeal joint of manual digit 1 namespace: uberon def: "An interphalangeal joint of manus that is part of a manual digit 1." [OBOL:automatic] subset: pheno_slim synonym: "interphalangeal joint of first digit of hand" EXACT [FMA:35312] synonym: "interphalangeal joint of hand digit 1" EXACT [] synonym: "interphalangeal joint of manual digit 1" EXACT [] synonym: "interphalangeal joint of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "interphalangeal joint of pollex" EXACT [] synonym: "interphalangeal joint of thumb" NARROW SENSU [FMA:35312, NCBITaxon:9606] xref: EMAPA:25058 xref: FMA:35312 xref: NCIT:C102306 xref: SCTID:182192008 is_a: UBERON:0007722 ! interphalangeal joint of manus intersection_of: UBERON:0007722 ! interphalangeal joint of manus intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: connects UBERON:0003620 {cardinality="2"} ! manual digit 1 phalanx relationship: part_of UBERON:0001463 ! manual digit 1 property_value: UBPROP:0000008 "in humans, this connects proximal and distal phalanges of the thumb, so there is only a single inter-phalangeal joint - i.e. there is no distinct proximal and distal joints" xsd:string [Term] id: UBERON:0007724 name: interphalangeal joint of pedal digit 1 namespace: uberon def: "An interphalangeal joint of pes that is part of a pedal digit 1." [OBOL:automatic] synonym: "interphalangeal joint of big toe" NARROW SENSU [FMA:35353, NCBITaxon:9606] synonym: "interphalangeal joint of first digit of foot" EXACT [FMA:35353] synonym: "interphalangeal joint of first digit of pes" EXACT [FMA:35353] synonym: "interphalangeal joint of first toe" RELATED [FMA:35353] synonym: "interphalangeal joint of foot digit 1" EXACT [] synonym: "interphalangeal joint of great toe" EXACT [FMA:35353] synonym: "interphalangeal joint of hallux" EXACT [] synonym: "interphalangeal joint of pedal digit 1" EXACT [] synonym: "interphalangeal joint of pedal digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:26430 xref: FMA:35353 xref: SCTID:363671008 is_a: UBERON:0007721 ! interphalangeal joint of pes intersection_of: UBERON:0007721 ! interphalangeal joint of pes intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: connects UBERON:0003640 {cardinality="2"} ! pedal digit 1 phalanx relationship: part_of UBERON:0003631 ! pedal digit 1 [Term] id: UBERON:0007725 name: interphalangeal joint of pedal digit 2 namespace: uberon def: "An interphalangeal joint of pes that is part of a pedal digit 2." [OBOL:automatic] synonym: "interphalangeal joint of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "interphalangeal joint of second digit of foot" EXACT [FMA:35356] synonym: "interphalangeal joint of second toe" NARROW SENSU [FMA:35356, NCBITaxon:9606] xref: EMAPA:26448 xref: FMA:35356 is_a: UBERON:0007721 ! interphalangeal joint of pes intersection_of: UBERON:0007721 ! interphalangeal joint of pes intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: connects UBERON:0003641 {cardinality="2"} ! pedal digit 2 phalanx relationship: part_of UBERON:0003632 ! pedal digit 2 [Term] id: UBERON:0007726 name: interphalangeal joint of pedal digit 3 namespace: uberon def: "An interphalangeal joint of pes that is part of a pedal digit 3." [OBOL:automatic] synonym: "interphalangeal joint of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "interphalangeal joint of third digit of foot" EXACT [FMA:35359] synonym: "interphalangeal joint of third toe" NARROW SENSU [FMA:35359, NCBITaxon:9606] xref: EMAPA:26454 xref: FMA:35359 is_a: UBERON:0007721 ! interphalangeal joint of pes intersection_of: UBERON:0007721 ! interphalangeal joint of pes intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: connects UBERON:0003642 {cardinality="2"} ! pedal digit 3 phalanx relationship: part_of UBERON:0003633 ! pedal digit 3 [Term] id: UBERON:0007727 name: interphalangeal joint of pedal digit 4 namespace: uberon def: "An interphalangeal joint of pes that is part of a pedal digit 4." [OBOL:automatic] synonym: "interphalangeal joint of fourth digit of foot" EXACT [FMA:35362] synonym: "interphalangeal joint of fourth toe" NARROW SENSU [FMA:35362, NCBITaxon:9606] synonym: "interphalangeal joint of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:26466 xref: FMA:35362 is_a: UBERON:0007721 ! interphalangeal joint of pes intersection_of: UBERON:0007721 ! interphalangeal joint of pes intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: connects UBERON:0003862 {cardinality="2"} ! pedal digit 4 phalanx relationship: part_of UBERON:0003634 ! pedal digit 4 [Term] id: UBERON:0007728 name: interphalangeal joint of pedal digit 5 namespace: uberon def: "An interphalangeal joint of pes that is part of a pedal digit 5." [OBOL:automatic] synonym: "interphalangeal joint of fifth digit of foot" EXACT [FMA:35365] synonym: "interphalangeal joint of fifth toe" EXACT [FMA:35365] synonym: "interphalangeal joint of little toe" NARROW SENSU [FMA:35365, NCBITaxon:9606] synonym: "interphalangeal joint of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:26478 xref: FMA:35365 is_a: UBERON:0007721 ! interphalangeal joint of pes intersection_of: UBERON:0007721 ! interphalangeal joint of pes intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: connects UBERON:0003863 {cardinality="2"} ! pedal digit 5 phalanx relationship: part_of UBERON:0003635 ! pedal digit 5 [Term] id: UBERON:0007729 name: interphalangeal joint of manual digit 2 namespace: uberon def: "An interphalangeal joint of manus that is part of a manual digit 2." [OBOL:automatic] synonym: "interphalangeal joint of index finger" NARROW SENSU [FMA:35397, NCBITaxon:9606] synonym: "interphalangeal joint of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "interphalangeal joint of second digit of hand" EXACT [FMA:35397] synonym: "interphalangeal joint of second finger" EXACT [FMA:35397] xref: EMAPA:25061 xref: FMA:35397 is_a: UBERON:0007722 ! interphalangeal joint of manus intersection_of: UBERON:0007722 ! interphalangeal joint of manus intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: connects UBERON:0003641 {cardinality="2"} ! pedal digit 2 phalanx relationship: part_of UBERON:0003622 {source="EMAPA"} ! manual digit 2 [Term] id: UBERON:0007730 name: interphalangeal joint of manual digit 3 namespace: uberon def: "An interphalangeal joint of manus that is part of a manual digit 3." [OBOL:automatic] synonym: "interphalangeal joint of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "interphalangeal joint of middle finger" NARROW SENSU [FMA:35400, NCBITaxon:9606] synonym: "interphalangeal joint of third digit of hand" EXACT [FMA:35400] synonym: "interphalangeal joint of third finger" EXACT [FMA:35400] xref: EMAPA:25064 xref: FMA:35400 is_a: UBERON:0007722 ! interphalangeal joint of manus intersection_of: UBERON:0007722 ! interphalangeal joint of manus intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: connects UBERON:0003642 {cardinality="2"} ! pedal digit 3 phalanx relationship: part_of UBERON:0003623 ! manual digit 3 [Term] id: UBERON:0007731 name: interphalangeal joint of manual digit 4 namespace: uberon def: "An interphalangeal joint of manus that is part of a manual digit 4." [OBOL:automatic] synonym: "interphalangeal joint of fourth digit of hand" EXACT [FMA:35403] synonym: "interphalangeal joint of fourth finger" EXACT [FMA:35403] synonym: "interphalangeal joint of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "interphalangeal joint of ring finger" NARROW SENSU [FMA:35403, NCBITaxon:9606] xref: EMAPA:25067 xref: FMA:35403 is_a: UBERON:0007722 ! interphalangeal joint of manus intersection_of: UBERON:0007722 ! interphalangeal joint of manus intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: connects UBERON:0003862 {cardinality="2"} ! pedal digit 4 phalanx relationship: part_of UBERON:0003624 ! manual digit 4 [Term] id: UBERON:0007732 name: interphalangeal joint of manual digit 5 namespace: uberon def: "An interphalangeal joint of manus that is part of a manual digit 5." [OBOL:automatic] synonym: "interphalangeal joint of fifth digit of hand" EXACT [FMA:35407] synonym: "interphalangeal joint of fifth finger" EXACT [FMA:35407] synonym: "interphalangeal joint of little finger" NARROW SENSU [FMA:35407, NCBITaxon:9606] synonym: "interphalangeal joint of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:25070 xref: FMA:35407 is_a: UBERON:0007722 ! interphalangeal joint of manus intersection_of: UBERON:0007722 ! interphalangeal joint of manus intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: connects UBERON:0003863 {cardinality="2"} ! pedal digit 5 phalanx relationship: part_of UBERON:0003625 ! manual digit 5 [Term] id: UBERON:0007735 name: metacarpophalangeal joint of manual digit 1 namespace: uberon def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 1." [OBOL:automatic] subset: pheno_slim synonym: "metacarpo-phalangeal joint of digit 1 of fore-paw" NARROW [EMAPA:25057] synonym: "metacarpophalangeal joint of digit 1" EXACT [] synonym: "metacarpophalangeal joint of first digit of hand" EXACT [FMA:35249] synonym: "metacarpophalangeal joint of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpophalangeal joint of thumb" NARROW SENSU [FMA:35249, NCBITaxon:9606] xref: EMAPA:25057 xref: FMA:35249 xref: SCTID:361844001 is_a: UBERON:0003695 ! metacarpophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004338 ! proximal phalanx of manual digit 1 relationship: connects UBERON:0004338 ! proximal phalanx of manual digit 1 relationship: part_of UBERON:0001463 {source="FMA"} ! manual digit 1 [Term] id: UBERON:0007738 name: metacarpophalangeal joint of manual digit 2 namespace: uberon def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 2." [OBOL:automatic] synonym: "metacarpo-phalangeal joint of digit 2 of fore-paw" NARROW [EMAPA:25060] synonym: "metacarpophalangeal joint of digit 2" EXACT [] synonym: "metacarpophalangeal joint of index finger" NARROW SENSU [FMA:35252, NCBITaxon:9606] synonym: "metacarpophalangeal joint of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpophalangeal joint of second digit of hand" EXACT [FMA:35252] synonym: "metacarpophalangeal joint of second finger" EXACT [FMA:35252] xref: EMAPA:25060 xref: FMA:35252 xref: SCTID:361845000 is_a: UBERON:0003695 ! metacarpophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004328 ! proximal phalanx of manual digit 2 relationship: connects UBERON:0004328 ! proximal phalanx of manual digit 2 relationship: part_of UBERON:0003622 {source="FMA"} ! manual digit 2 [Term] id: UBERON:0007741 name: metacarpophalangeal joint of manual digit 3 namespace: uberon def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 3." [OBOL:automatic] subset: pheno_slim synonym: "carpometacarpophalangeal joint of third digit" NARROW SENSU [NCBITaxon:8782] synonym: "metacarpo-phalangeal joint of digit 3 of fore-paw" NARROW [EMAPA:25063] synonym: "metacarpophalangeal joint of digit 3" EXACT [] synonym: "metacarpophalangeal joint of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpophalangeal joint of middle finger" NARROW SENSU [FMA:35255, NCBITaxon:9606] synonym: "metacarpophalangeal joint of third digit of hand" EXACT [FMA:35255] synonym: "metacarpophalangeal joint of third finger" EXACT [FMA:35255] xref: EMAPA:25063 xref: FMA:35255 xref: SCTID:361846004 is_a: UBERON:0003695 ! metacarpophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004329 ! proximal phalanx of manual digit 3 relationship: connects UBERON:0004329 ! proximal phalanx of manual digit 3 relationship: part_of UBERON:0003623 {source="FMA"} ! manual digit 3 [Term] id: UBERON:0007744 name: metacarpophalangeal joint of manual digit 4 namespace: uberon def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 4." [OBOL:automatic] subset: pheno_slim synonym: "carpometacarpophalangeal joint of fourth digit" NARROW SENSU [NCBITaxon:8782] synonym: "metacarpo-phalangeal joint of digit 4 of fore-paw" NARROW [EMAPA:25066] synonym: "metacarpophalangeal joint of digit 4" EXACT [] synonym: "metacarpophalangeal joint of fourth digit of hand" EXACT [FMA:35258] synonym: "metacarpophalangeal joint of fourth finger" EXACT [FMA:35258] synonym: "metacarpophalangeal joint of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpophalangeal joint of ring finger" NARROW SENSU [FMA:35258, NCBITaxon:9606] xref: EMAPA:25066 xref: FMA:35258 xref: SCTID:361847008 is_a: UBERON:0003695 ! metacarpophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004330 ! proximal phalanx of manual digit 4 relationship: connects UBERON:0004330 ! proximal phalanx of manual digit 4 relationship: part_of UBERON:0003624 {source="FMA"} ! manual digit 4 [Term] id: UBERON:0007747 name: metacarpophalangeal joint of manual digit 5 namespace: uberon def: "A skeletal joint that connects a metacarpal bone and connects a proximal phalanx of manual digit 5." [OBOL:automatic] subset: pheno_slim synonym: "metacarpo-phalangeal joint of digit 5 of fore-paw" NARROW [EMAPA:25069] synonym: "metacarpophalangeal joint of digit 5" EXACT [] synonym: "metacarpophalangeal joint of fifth digit of hand" EXACT [FMA:35261] synonym: "metacarpophalangeal joint of fifth finger" EXACT [FMA:35261] synonym: "metacarpophalangeal joint of little finger" NARROW SENSU [FMA:35261, NCBITaxon:9606] synonym: "metacarpophalangeal joint of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:25069 xref: FMA:35261 xref: SCTID:361848003 is_a: UBERON:0003695 ! metacarpophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 ! metacarpal bone intersection_of: connects UBERON:0004331 ! proximal phalanx of manual digit 5 relationship: connects UBERON:0004331 ! proximal phalanx of manual digit 5 relationship: part_of UBERON:0003625 {source="FMA"} ! manual digit 5 [Term] id: UBERON:0007750 name: metatarsophalangeal joint of pedal digit 1 namespace: uberon def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 1." [OBOL:automatic] subset: pheno_slim synonym: "first metatarsophalangeal joint" EXACT [] synonym: "metatarsophalangeal joint of big toe" NARROW SENSU [FMA:35228, NCBITaxon:9606] synonym: "metatarsophalangeal joint of first digit of foot" EXACT [FMA:35228] synonym: "metatarsophalangeal joint of first toe" RELATED [FMA:35228] synonym: "metatarsophalangeal joint of great toe" EXACT [FMA:35228] synonym: "metatarsophalangeal joint of pedal digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:26436 xref: FMA:35228 xref: NCIT:C102321 xref: SCTID:182223003 is_a: UBERON:0003696 ! metatarsophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004315 ! distal phalanx of pedal digit 1 relationship: connects UBERON:0004315 ! distal phalanx of pedal digit 1 relationship: part_of UBERON:0003631 {source="FMA"} ! pedal digit 1 property_value: UBPROP:0000012 "the name of the structure in EMAPA is incorrect" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0007753 name: metatarsophalangeal joint of pedal digit 2 namespace: uberon def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 2." [OBOL:automatic] subset: pheno_slim synonym: "metatarsophalangeal joint of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metatarsophalangeal joint of second digit of foot" EXACT [FMA:35231] synonym: "metatarsophalangeal joint of second toe" NARROW SENSU [FMA:35231, NCBITaxon:9606] xref: EMAPA:26442 xref: FMA:35231 xref: SCTID:361869001 is_a: UBERON:0003696 ! metatarsophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: connects UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: part_of UBERON:0003632 {source="FMA"} ! pedal digit 2 property_value: UBPROP:0000012 "the name of the structure in EMAPA is incorrect" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0007756 name: metatarsophalangeal joint of pedal digit 3 namespace: uberon def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 3." [OBOL:automatic] subset: pheno_slim synonym: "metatarsophalangeal joint of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metatarsophalangeal joint of third digit of foot" EXACT [FMA:35234] synonym: "metatarsophalangeal joint of third toe" NARROW SENSU [FMA:35234, NCBITaxon:9606] xref: EMAPA:26460 xref: FMA:35234 xref: SCTID:361870000 is_a: UBERON:0003696 ! metatarsophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: connects UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: part_of UBERON:0003633 {source="FMA"} ! pedal digit 3 property_value: UBPROP:0000012 "the name of the structure in EMAPA is incorrect" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0007759 name: metatarsophalangeal joint of pedal digit 4 namespace: uberon def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 4." [OBOL:automatic] subset: pheno_slim synonym: "metatarsophalangeal joint of fourth digit of foot" EXACT [FMA:35237] synonym: "metatarsophalangeal joint of fourth toe" NARROW SENSU [FMA:35237, NCBITaxon:9606] synonym: "metatarsophalangeal joint of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:26472 xref: FMA:35237 xref: SCTID:361871001 is_a: UBERON:0003696 ! metatarsophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: connects UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: part_of UBERON:0003634 {source="FMA"} ! pedal digit 4 property_value: UBPROP:0000012 "the name of the structure in EMAPA is incorrect" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0007762 name: metatarsophalangeal joint of pedal digit 5 namespace: uberon def: "A skeletal joint that connects a metatarsal bone and connects a distal phalanx of pedal digit 5." [OBOL:automatic] subset: pheno_slim synonym: "metatarsophalangeal joint of fifth digit of foot" EXACT [FMA:35240] synonym: "metatarsophalangeal joint of fifth toe" EXACT [FMA:35240] synonym: "metatarsophalangeal joint of little toe" NARROW SENSU [FMA:35240, NCBITaxon:9606] synonym: "metatarsophalangeal joint of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:26484 xref: FMA:35240 xref: SCTID:361872008 is_a: UBERON:0003696 ! metatarsophalangeal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 ! metatarsal bone intersection_of: connects UBERON:0004319 ! distal phalanx of pedal digit 5 relationship: connects UBERON:0004319 ! distal phalanx of pedal digit 5 relationship: part_of UBERON:0003635 {source="FMA"} ! pedal digit 5 property_value: UBPROP:0000012 "the name of the structure in EMAPA is incorrect" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0007771 name: epidermis gland namespace: uberon def: "A gland that is part of a epidermis." [OBOL:automatic] subset: grouping_class synonym: "epidermal gland" EXACT [] synonym: "gland of epidermis" EXACT [FMA:59153] xref: FMA:59153 is_a: UBERON:0002419 ! skin gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001003 ! skin epidermis relationship: part_of UBERON:0001003 ! skin epidermis [Term] id: UBERON:0007774 name: secondary dentition namespace: uberon def: "The teeth of adulthood that either replace or are added to the complement of deciduous teeth. (Boucher's Clinical Dental Terminology, 4th ed)." [MESH:A14.254.237] subset: pheno_slim synonym: "adult dentition" RELATED [GAID:1251] synonym: "dentes permanentes" EXACT LATIN [FMA:75152, FMA:TA] synonym: "permanent dentition" EXACT [GAID:1251] synonym: "permanent teeth" EXACT [FMA:75152] synonym: "secondary dentition" RELATED [GAID:1251] synonym: "set of permanent teeth" EXACT [FMA:75152] synonym: "set of secondary teeth" EXACT [FMA:75152] xref: FMA:75152 xref: GAID:1251 xref: MESH:D019229 is_a: UBERON:0003672 {source="FMA"} ! dentition intersection_of: UBERON:0003672 ! dentition intersection_of: developmentally_replaces UBERON:0007116 ! primary dentition relationship: developmentally_replaces UBERON:0007116 ! primary dentition [Term] id: UBERON:0007775 name: secondary tooth namespace: uberon def: "A tooth that forms after a primary tooth." [http://orcid.org/0000-0002-6601-2165] comment: GAT in FMA subset: pheno_slim synonym: "dentes permanentes" RELATED LATIN [Wikipedia:Permanent_teeth] synonym: "permanent tooth" EXACT [FMA:55654] xref: FMA:55654 xref: NCIT:C33313 xref: SCTID:245563006 xref: UMLS:C0348070 {source="ncithesaurus:Permanent_Tooth"} xref: Wikipedia:Permanent_teeth is_a: UBERON:0001091 ! calcareous tooth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: part_of UBERON:0007774 ! secondary dentition relationship: part_of UBERON:0007774 ! secondary dentition property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/1/14/Teeth_by_David_Shankbone.jpg" xsd:anyURI [Term] id: UBERON:0007778 name: umbilical artery endothelium namespace: uberon def: "An endothelium that is part of a umbilical artery." [OBOL:automatic] xref: BTO:0000857 is_a: UBERON:0001917 ! endothelium of artery intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001310 ! umbilical artery relationship: part_of UBERON:0001310 {source="BTO"} ! umbilical artery [Term] id: UBERON:0007779 name: transudate namespace: uberon def: "Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces." [http://medical-dictionary.thefreedictionary.com/transudate] synonym: "plasma ultrafiltrate" RELATED [] xref: FMA:12276 xref: GAID:1195 xref: MESH:D005122 xref: ncithesaurus:Transudate is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0000463 ! organism substance intersection_of: filtered_through UBERON:0001982 ! capillary intersection_of: has_quality PATO:0001548 ! quality of a liquid intersection_of: transformation_of UBERON:0001969 ! blood plasma relationship: develops_from UBERON:0001969 ! blood plasma relationship: filtered_through UBERON:0001982 ! capillary relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: transformation_of UBERON:0001969 ! blood plasma property_value: UBPROP:0000007 "transudative" xsd:string property_value: UBPROP:0000010 "characteristically low in protein and cellular content (unless there has been secondary concentration)" xsd:string [Term] id: UBERON:0007794 name: secretion of serous gland namespace: uberon def: "Any fluid produced by a serous gland." [UBERON:cjm] synonym: "serosal fluid" EXACT [Wikipedia:Serous_fluid] synonym: "serous fluid" BROAD [] synonym: "serous gland fluid" EXACT [] xref: Wikipedia:Serous_fluid is_a: UBERON:0000456 ! secretion of exocrine gland is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0006314 ! bodily fluid intersection_of: produced_by UBERON:0000409 ! serous gland relationship: produced_by UBERON:0000409 ! serous gland [Term] id: UBERON:0007798 name: vascular system namespace: uberon def: "Anatomical system that consists of all blood and lymph vessels." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim xref: BTO:0001085 xref: CALOHA:TS-2053 xref: EHDAA2:0004520 xref: EMAPA:35905 xref: MA:0002718 xref: NCIT:C33854 xref: UMLS:C0489903 {source="ncithesaurus:Vascular_System"} is_a: UBERON:0000467 ! anatomical system relationship: part_of UBERON:0004535 {source="MA"} ! cardiovascular system property_value: editor_note "consider merging with vasculature" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The cardiovascular and lymphatic systems, collectively[ncithesaurus:Vascular_System]." xsd:string {source="ncithesaurus:Vascular_System"} property_value: UBPROP:0000012 "in both MA and BTO, the arterial system and venous sytem are subtypes of the vascular system" xsd:string {external_ontology="MA"} [Term] id: UBERON:0007806 name: connecting stalk namespace: uberon def: "A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord." [http://medical-dictionary.thefreedictionary.com/] xref: BTO:0004705 xref: NCIT:C34132 xref: UMLS:C1516792 {source="ncithesaurus:Connecting_Stalk"} is_a: UBERON:0000478 {source="EHDAA2"} ! extraembryonic structure relationship: develops_from UBERON:0005728 {source="EHDAA2"} ! extraembryonic mesoderm property_value: editor_note "TODO - this is currently defined as a bridge of mesoderm, but in EHDAA2 is extraembryonic structure split into mesoderm and blood vessels" xsd:string [Term] id: UBERON:0007807 name: connecting stalk vasculature namespace: uberon def: "A vasculature that is part of a connecting stalk." [OBOL:automatic] synonym: "connecting stalk blood vessel" RELATED [] synonym: "connecting stalk blood vessels" EXACT [EHDAA2:0000313] synonym: "vasculature of connecting stalk" RELATED [] xref: EHDAA2:0000313 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0007806 ! connecting stalk relationship: develops_from UBERON:0011921 {source="EHDAA2"} ! connecting stalk blood islands relationship: part_of UBERON:0007806 ! connecting stalk [Term] id: UBERON:0007808 name: adipose tissue of abdominal region namespace: uberon def: "Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots." [CALOHA:paula, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/259, MGI:csmith] subset: efo_slim synonym: "abdominal adipose tissue" RELATED [BTO:0004041] synonym: "abdominal fat" RELATED [BTO:0004041] synonym: "intra-abdominal fat" RELATED [BTO:0004041] xref: CALOHA:TS-0002 xref: EFO:0003771 is_a: UBERON:0001013 ! adipose tissue is_a: UBERON:0003567 ! abdomen connective tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0000916 ! abdomen relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cindyJax relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/paulacalipho [Term] id: UBERON:0007811 name: craniocervical region namespace: uberon def: "The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "cephalic area" RELATED [https://github.com/obophenotype/uberon/issues/379] synonym: "cephalic part of animal" RELATED [Wikipedia:Head] synonym: "cephalic region" RELATED [https://github.com/obophenotype/uberon/issues/379] synonym: "head and neck" RELATED [FMA:280881] synonym: "head or neck" RELATED [] xref: CALOHA:TS-2356 xref: EV:0100009 xref: FMA:280881 xref: galen:HeadAndNeck xref: MA:0000006 xref: NCIT:C12418 xref: SCTID:361355005 xref: UMLS:C0460004 {source="ncithesaurus:Head_and_Neck"} xref: WikipediaCategory:Head_and_neck is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000475 {source="MA"} ! organism subdivision relationship: has_part UBERON:0000033 ! head relationship: has_part UBERON:0000974 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! neck relationship: has_part UBERON:0006562 ! pharynx relationship: part_of UBERON:0000153 ! anterior region of body relationship: part_of UBERON:0013702 ! body proper [Term] id: UBERON:0007812 name: post-anal tail namespace: uberon def: "A tail that extends from the posterior tip of the organism to the anus, contains muscle and skeleton." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim subset: vertebrate_core synonym: "muscular postanal tail" EXACT [] synonym: "post-anal fin tail" NARROW SENSU [http://purl.oboibrary.org/obo/uberon/tracker/185] synonym: "post-vent region" RELATED [TAO:0001117] synonym: "postanal tail" EXACT [] xref: AAO:0010338 xref: EMAPA:16748 xref: MA:0000008 xref: NCIT:C77663 xref: TAO:0001117 xref: UMLS:C0039259 {source="ncithesaurus:Tail"} xref: XAO:0003026 xref: ZFA:0001117 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002415 ! tail intersection_of: UBERON:0002415 ! tail intersection_of: part_of UBERON:0006071 ! caudal region relationship: capable_of_part_of GO:0007626 ! locomotory behavior relationship: develops_from UBERON:0007144 ! embryonic post-anal tail relationship: only_in_taxon NCBITaxon:7711 {notes="possible exception in hemichordates", source="cjm"} ! Chordata relationship: part_of UBERON:0006071 ! caudal region relationship: transformation_of UBERON:0007144 ! embryonic post-anal tail property_value: RO:0002161 NCBITaxon:314295 property_value: UBPROP:0000001 "Anatomical structure that is the terminal, flexible posterior appendage of the organism.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010338", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "Organism subdivision which is the part of the body posterior to the vent which includes the anal and caudal fins.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001117", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000008 "present at some time in chordate life history (eg in Urochordates, present only in free-swimming larvae). Function: propellor locomotion (in some species)" xsd:string [Term] id: UBERON:0007823 name: appendage girdle region namespace: uberon alt_id: UBERON:0007824 def: "An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "fin girdle" RELATED SENSU [] synonym: "fin girdle region" RELATED SENSU [] synonym: "girdle" BROAD [] synonym: "girdle region" BROAD [] synonym: "limb girdle" RELATED SENSU [] synonym: "limb girdle region" RELATED SENSU [] xref: EMAPA:37854 {source="MA:th"} xref: FMA:24874 xref: VSAO:0000303 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000475 ! organism subdivision intersection_of: UBERON:0000475 ! organism subdivision intersection_of: has_skeleton UBERON:0010719 ! girdle skeleton relationship: has_skeleton UBERON:0010719 ! girdle skeleton relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0010707 ! appendage girdle complex property_value: IAO:0000232 "this encompasses non-skeletal tissue" xsd:string property_value: UBPROP:0000001 "An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). There are only two instances of appendage girdle regions per organism.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000303", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"} [Term] id: UBERON:0007826 name: peritoneal mesentery namespace: uberon def: "Mesentery that is located in the peritoneum." [UBERON:cjm] xref: FMA:20570 xref: TAO:0005129 xref: XAO:0000138 xref: ZFA:0005129 is_a: UBERON:0002095 ! mesentery is_a: UBERON:0002358 ! peritoneum intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0002358 ! peritoneum relationship: part_of UBERON:0001178 {source="FMA"} ! visceral peritoneum [Term] id: UBERON:0007827 name: external nose namespace: uberon def: "External part of the nose containing the external nares." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "nose" RELATED [] xref: EMAPA:37831 {source="MA:th"} xref: FMA:59515 xref: NCIT:C32566 xref: SCTID:265785009 xref: UMLS:C0458561 {source="ncithesaurus:External_Nose"} is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034929 ! external soft tissue zone intersection_of: UBERON:0034929 ! external soft tissue zone intersection_of: has_part UBERON:0005928 ! external naris intersection_of: part_of UBERON:0000004 ! nose relationship: has_part UBERON:0005928 ! external naris relationship: part_of UBERON:0000004 ! nose property_value: UBPROP:0000001 "Subdivision of face, the exterior of the nose, which consists of a root, dorsum, tip, columella, and right and left alae[FMA:59515]." xsd:string {source="FMA:59515"} [Term] id: UBERON:0007828 name: girdle bone/zone namespace: uberon def: "A bone that is part of a appendage girdle region." [OBOL:automatic] synonym: "girdle bone" EXACT [MA:0000291] xref: EMAPA:35379 xref: MA:0000291 is_a: UBERON:0010740 ! bone of appendage girdle complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007823 ! appendage girdle region relationship: part_of UBERON:0010719 ! girdle skeleton [Term] id: UBERON:0007829 name: pectoral girdle bone namespace: uberon def: "A bone that is part of a pectoral girdle region." [OBOL:automatic] subset: human_reference_atlas subset: vertebrate_core synonym: "bone of pectoral girdle" EXACT [] xref: EMAPA:35669 xref: MA:0000292 is_a: UBERON:0007828 {source="MA"} ! girdle bone/zone is_a: UBERON:0010741 ! bone of pectoral complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001421 ! pectoral girdle region relationship: part_of UBERON:0007831 ! pectoral girdle skeleton property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0007830 name: pelvic girdle bone/zone namespace: uberon def: "A bone element or fused bone that is part of pelvic girdle." [https://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas subset: pheno_slim subset: vertebrate_core synonym: "bone of pelvic girdle" EXACT [] synonym: "pelvic girdle bone" EXACT [MA:0000293] xref: EMAPA:18028 xref: MA:0000293 xref: NCIT:C33287 xref: SCTID:426214007 xref: UMLS:C0030786 {source="ncithesaurus:Pelvic_Bone"} is_a: UBERON:0003828 ! abdominal segment bone is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0005913 ! zone of bone organ is_a: UBERON:0007828 {source="MA"} ! girdle bone/zone is_a: UBERON:0010742 ! bone of pelvic complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007832 ! pelvic girdle skeleton relationship: part_of UBERON:0007832 ! pelvic girdle skeleton property_value: editor_note "check sacrum, coccyx (MA does NOT include these)" xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "typically the ilium, ischium and pubis. These can alternately be considered individual bones, or zones of a single fused bone" xsd:string [Term] id: UBERON:0007831 name: pectoral girdle skeleton namespace: uberon def: "A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons." [Wikipedia:Pectoral_girdle] subset: efo_slim subset: vertebrate_core synonym: "cingulum pectorale" RELATED LATIN [Wikipedia:Pectoral_girdle] synonym: "pectoral girdle" RELATED INCONSISTENT [VSAO:0000156] synonym: "scapular girdle" RELATED [TAO:0000407] synonym: "skeletal parts of pectoral girdle" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "skeleton of pectoral girdle" EXACT [https://orcid.org/0000-0002-6601-2165] xref: AAO:0000422 xref: AAO:0000754 xref: EFO:0000946 xref: EHDAA2:0001420 xref: FMA:24141 xref: MAT:0000181 xref: MIAA:0000181 xref: NCIT:C33547 xref: TAO:0000407 xref: UMLS:C0427245 {source="ncithesaurus:Shoulder_Girdle"} xref: VHOG:0001156 xref: VSAO:0000156 xref: Wikipedia:Pectoral_girdle xref: XAO:0003063 xref: ZFA:0000407 is_a: UBERON:0010719 ! girdle skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: part_of UBERON:0001421 ! pectoral girdle region intersection_of: skeleton_of UBERON:0001421 ! pectoral girdle region relationship: part_of UBERON:0001421 ! pectoral girdle region relationship: part_of UBERON:0012475 ! skeleton of pectoral complex relationship: skeleton_of UBERON:0001421 ! pectoral girdle region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/22/Pectoral_girdle_front_diagram.svg" xsd:anyURI property_value: UBPROP:0000001 "Anatomical cluster of paired dermal and endochondral bones that attaches to the dorso-posterior part of the cranium, and support the radials and pectoral fin. It consists of two components: the primary pectoral girdle consisting of the endochondral coracoid, scapula and mesocoracoid bones, and the secondary pectoral girdle consisting of the dermal posttemporal, supracleithrum, cleithrum and poscleithrum(thra) bones.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000407", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "Girdle skeleton consisting of a set of bones linking the axial series to the forelimb/fin skeleton and offering anchoring areas for forelimb/fin and caudal musculature.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000156", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"} property_value: UBPROP:0000001 "Skeletal structure immediately behind the head attached to the vertebral column by muscles and supporting the forelimbs.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000422", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "The pectoral girdle is clearly of dual origin, composed of dermal as well as endochondral bones. The endochondral component, the scapulocoracoid, evolved by fusion or enlargment of several basal fin elements. (...) The dermal component of the shoulder girdle evolved from dermal bones of the body's surface. (...) Like endochondral bones, these dermal bones were passed along to tetrapods (...).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001156", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.336 and Figure 9.18", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "Note that the VSAO and many ontologies use the label 'pectoral girdle' to denote the skeletal region specifically." xsd:string {external_ontology="VSAO"} [Term] id: UBERON:0007832 name: pelvic girdle skeleton namespace: uberon def: "Skeletal subdivision consisting of a set of bones linking the axial series to the hindlimb zeugopodium and offering anchoring areas for hindlimb and caudal musculature." [VSAO:0000155, Wikipedia:Pelvis] subset: efo_slim subset: vertebrate_core synonym: "pelvic girdle" RELATED INCONSISTENT [VSAO:0000155] synonym: "pelvic girdle skeleton" EXACT [VSAO:0000155] synonym: "skeletal parts of pelvic girdle" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "skeleton of pelvic girdle" EXACT [https://orcid.org/0000-0002-6601-2165] xref: AAO:0000426 xref: AAO:0000768 xref: EFO:0000947 xref: EHDAA2:0001426 xref: EHDAA:7149 xref: EHDAA:8324 xref: EMAPA:18028 xref: FMA:87592 xref: galen:PelvicGirdle xref: http://people.eku.edu/ritchisong/pectoralgirdles.gif xref: MAT:0000182 xref: MIAA:0000182 xref: TAO:0000565 xref: VHOG:0000305 xref: VSAO:0000155 xref: Wikipedia:Pelvis xref: XAO:0003064 xref: ZFA:0000565 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010719 ! girdle skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: part_of UBERON:0001271 ! pelvic girdle region intersection_of: skeleton_of UBERON:0001271 ! pelvic girdle region relationship: develops_from UBERON:0010377 {source="PMID:21455939"} ! mesenchyme from somatopleure relationship: part_of UBERON:0001271 ! pelvic girdle region relationship: part_of UBERON:0012476 ! skeleton of pelvic complex relationship: skeleton_of UBERON:0001271 ! pelvic girdle region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/fe/Gray242.png" xsd:anyURI property_value: editor_note "need to resolve whether this is a paired structure or a single belt (Paired in FMA - implicitly paired in VSAO)" xsd:string property_value: UBPROP:0000001 "Anatomical cluster by which the hind limbs are supported and attached to the vertebral column.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000426", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "Anatomical cluster that consists of the paired basipterygia which support the pelvic fin.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000565", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "Girdle skeleton consisting of a set of bones linking the axial series to the hindlimb/fin skeleton and offering anchoring areas for hindlimb/fin and caudal musculature.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000155", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"} property_value: UBPROP:0000003 "The pelvic girdle is never joined by contributions of dermal bone. From its first appearance in placoderms, the pelvic girdle is exclusively endoskeletal. It arose from pterygiophores, perhaps several times, in support of the fin.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000305", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.333", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "Note that the VSAO and many ontologies use the label 'pelvic girdle' to denote the skeletal region specifically. We place the EHDAA2 class here, note that this includes the pre-cartilage condensation as parts" xsd:string {external_ontology="VSAO"} [Term] id: UBERON:0007842 name: membrane bone namespace: uberon def: "Bone element that arises as a result of intramembranous ossification." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/267, VSAO:0000023] synonym: "membrane bones" RELATED PLURAL [ZFA:0001636] xref: AEO:0000085 xref: EHDAA2:0003085 xref: TAO:0001645 xref: VSAO:0000023 xref: XAO:0004014 xref: ZFA:0001636 is_a: UBERON:0001474 {source="VSAO"} ! bone element relationship: output_of GO:0001957 ! intramembranous ossification property_value: UBPROP:0000001 "Bone element that arises as a result of intramembranous ossification.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000023", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Intramembranous bone that forms deep in the organism.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001645", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0007844 name: cartilage element namespace: uberon def: "Skeletal element that is composed of cartilage tissue and may be permanent or transient." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000000] subset: organ_slim subset: pheno_slim synonym: "cartilage" RELATED [VSAO:0000000] synonym: "cartilage organ" EXACT [FMA:55107] synonym: "cartilaginous element" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "chondrogenic element" EXACT [VSAO:0000000] xref: AAO:0011130 xref: CALOHA:TS-0118 xref: EMAPA:32730 xref: FMA:55107 xref: VSAO:0000000 xref: XAO:0004013 xref: ZFA:0001501 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004765 {source="VSAO"} ! skeletal element intersection_of: UBERON:0004765 ! skeletal element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0005863 {source="VSAO"} ! cartilaginous condensation relationship: has_part UBERON:0002418 {source="VSAO"} ! cartilage tissue property_value: UBPROP:0000012 "TAO still mixes tissue and element" xsd:string {external_ontology="TAO"} [Term] id: UBERON:0007845 name: regular connective tissue namespace: uberon def: "Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue." [FMA:20103] xref: FMA:20103 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002384 {source="FMA"} ! connective tissue disjoint_from: UBERON:0011821 ! irregular connective tissue relationship: has_part CL:0000057 ! fibroblast relationship: has_part GO:0071953 ! elastic fiber relationship: has_part UBERON:0011860 ! collection of collagen fibrils property_value: editor_note "the connective tissue hierarchy largely follows FMA with definitions from VSAO. Note that in FMA, loose-CT is irregular-CT. This means regular-CT is necessarily equivalent to dense-regular-CT (assuming a JEPD classification)." xsd:string [Term] id: UBERON:0007846 name: dense regular connective tissue namespace: uberon def: "Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts)." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000050] synonym: "dense fibrous connective tissue" EXACT [FMA:64781] synonym: "dense regular collagenous connective tissue" EXACT [FMA:64781] synonym: "dense regular collagenous tissue" EXACT [FMA:64781] synonym: "regular dense connective tissue" EXACT [] synonym: "typus regularis (textus connectivus collagenosus compactus)" EXACT [FMA:64781] xref: FMA:64781 xref: NCIT:C33453 xref: SCTID:22560007 xref: UMLS:C0225333 {source="ncithesaurus:Regular_Dense_Connective_Tissue"} xref: VSAO:0000050 xref: Wikipedia:Dense_regular_connective_tissue xref: XAO:0004030 is_a: UBERON:0007845 {source="FMA"} ! regular connective tissue is_a: UBERON:0011823 {source="ncithesaurus"} ! dense connective tissue intersection_of: UBERON:0007845 ! regular connective tissue intersection_of: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils intersection_of: has_part GO:0071953 ! elastic fiber property_value: UBPROP:0000001 "Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts).[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000050", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Regular connective tissue, the intercellular matrix of which consists predominantly of collagen fiber bundles arranged in parallel arrays.[FMA]" xsd:string {date_retrieved="2012-08-29", external_class="FMA:64781", ontology="FMA"} [Term] id: UBERON:0007914 name: bone of craniocervical region namespace: uberon def: "A bone that is part of a craniocervical region." [OBOL:automatic] synonym: "cranial bone" RELATED [] synonym: "head or neck bone" EXACT [MA:0000569] xref: EMAPA:37245 {source="MA:th"} xref: MA:0000569 is_a: UBERON:0001474 {source="MA"} ! bone element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0007811 {source="MA"} ! craniocervical region [Term] id: UBERON:0007997 name: sesamoid bone of manus namespace: uberon def: "A sesamoid bone that is part of a manus." [OBOL:automatic] synonym: "sesamoid bone of hand" EXACT [FMA:42353] xref: FMA:42353 xref: SCTID:368448000 is_a: UBERON:0001479 {source="FMA"} ! sesamoid bone is_a: UBERON:0005897 ! manus bone is_a: UBERON:0011141 ! appendicular ossicle intersection_of: UBERON:0001479 ! sesamoid bone intersection_of: part_of UBERON:0002398 ! manus [Term] id: UBERON:0008000 name: sesamoid bone of pes namespace: uberon def: "A sesamoid bone that is part of a pes." [OBOL:automatic] synonym: "sesamoid bone of foot" EXACT [FMA:45096] xref: FMA:45096 xref: SCTID:244675002 is_a: UBERON:0001479 {source="FMA"} ! sesamoid bone is_a: UBERON:0005899 ! pes bone is_a: UBERON:0011141 ! appendicular ossicle intersection_of: UBERON:0001479 ! sesamoid bone intersection_of: part_of UBERON:0002387 ! pes [Term] id: UBERON:0008001 name: irregular bone namespace: uberon def: "The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid." [Wikipedia:Irregular_bone] synonym: "os irregulare" EXACT [] synonym: "os irregulare" RELATED LATIN [Wikipedia:Irregular_bone] xref: FMA:7477 xref: NCIT:C32881 xref: SCTID:421560006 xref: UMLS:C0502414 {source="ncithesaurus:Irregular_Bone"} xref: Wikipedia:Irregular_bone is_a: UBERON:0001474 {source="FMA"} ! bone element [Term] id: UBERON:0008114 name: joint of girdle namespace: uberon def: "A skeletal joint that is part of a appendage girdle region." [OBOL:automatic] subset: grouping_class synonym: "girdle joint" EXACT [OBOL:automatic] xref: MA:0001505 is_a: UBERON:0000982 {source="MA"} ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0007823 ! appendage girdle region relationship: connects UBERON:0007828 ! girdle bone/zone relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0007823 ! appendage girdle region [Term] id: UBERON:0008115 name: surface of cartilage namespace: uberon def: "An anatomical surface that is part of a cartilage element." [OBOL:automatic] synonym: "cartilage surface" EXACT [FMA:76668] xref: FMA:76668 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0036215 ! anatomical surface region intersection_of: UBERON:0036215 ! anatomical surface region intersection_of: bounding_layer_of UBERON:0007844 ! cartilage element relationship: bounding_layer_of UBERON:0007844 ! cartilage element relationship: part_of UBERON:0007844 ! cartilage element [Term] id: UBERON:0008193 name: pneumatized bone namespace: uberon def: "A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]." [http://www.medilexicon.com/medicaldictionary.php?t=11303] synonym: "hollow bone" RELATED [] synonym: "os pneumaticum" EXACT [FMA:7478] synonym: "pneumatic bone" EXACT [FMA:7478] xref: FMA:7478 xref: galen:PneumaticBone xref: SCTID:333008005 xref: Wikipedia:Skeletal_pneumaticity is_a: UBERON:0001474 ! bone element intersection_of: UBERON:0001474 ! bone element intersection_of: has_part UBERON:0010528 ! pneumatic cavity of bone relationship: has_part UBERON:0010528 ! pneumatic cavity of bone property_value: editor_note "subclasses of this should be checked for taxonomic consistency" xsd:string property_value: UBPROP:0000008 "Skeletal pneumaticity is the presence of air spaces within bones. Skeletal pneumaticity exists only in synapsids and archosaurs. It is generally produced during development by excavation of bone by pneumatic diverticula (air sacs) from an air-filled space such as the lungs or nasal cavity. Pneumatization is highly variable between individuals, and bones not normally pneumatized can become pneumatized in pathological development. Pneumatization occurs in the skulls of mammals, crocodilians and birds among extant groups, as well as extinct archosaurs including the dinosaurs and pterosaurs. Pneumatic spaces include the paranasal sinuses and some of the mastoid cells[WP]. [Wikipedia:Skeletal_pneumaticity]" xsd:string [Term] id: UBERON:0008196 name: muscle of pectoral girdle namespace: uberon def: "Any muscle organ that is part of a pectoral girdle region." [OBOL:automatic] subset: pheno_slim synonym: "muscle of shoulder girdle" EXACT [FMA:37347] synonym: "pectoral girdle muscle" EXACT [FMA:37347] xref: EMAPA:17748 xref: FMA:37347 is_a: UBERON:0010891 ! pectoral complex muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0001421 ! pectoral girdle region relationship: part_of UBERON:0004471 ! musculature of pectoral girdle property_value: UBPROP:0000012 "EMAPA has both non-skeletal and skeletal types, with the non-skeletal also including a chest muscle, so we place the skeletal class here as the most accurate" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0008202 name: bone of hip region namespace: uberon subset: grouping_class subset: non_informative subset: pheno_slim xref: EMAPA:37308 {source="MA:th"} xref: FMA:42854 xref: MA:0000655 xref: SCTID:304907005 is_a: UBERON:0001474 ! bone element relationship: overlaps UBERON:0001464 {source="MA"} ! hip property_value: editor_note "todo - consider obsoletion" xsd:string property_value: UBPROP:0000012 "in MA, this includes the femur. i.e. pelvic girdle bone or femur; note that this makes the ilium etc in MA hindlimb bones. in MA this is a hindlimb bone" xsd:string {external_ontology="MA"} [Term] id: UBERON:0008203 name: pelvic cavity namespace: uberon def: "The part of the ventral body cavity that is within the pelvis." [UBERON:cjm] synonym: "cavitas pelvis" RELATED LATIN [Wikipedia:Pelvic_cavity] synonym: "space of pelvic compartment" EXACT [FMA:9738] xref: EMAPA:37235 {source="MA:th"} xref: FMA:9738 xref: MA:0003089 xref: SCTID:281903009 xref: Wikipedia:Pelvic_cavity is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002355 ! pelvic region of trunk intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen relationship: luminal_space_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0035819 ! abdominopelvic cavity property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI [Term] id: UBERON:0008229 name: craniocervical region musculature namespace: uberon def: "Musculature system of the pharyngeal and head regions." [ZFA:0000328, ZFA:curator] synonym: "head muscles" RELATED [ZFA:0000328] synonym: "head or neck muscle" EXACT [MA:0000571] synonym: "head or neck muscle" RELATED [MA:0000571] xref: EMAPA:37259 {source="MA:th"} xref: MA:0000571 xref: TAO:0000328 xref: ZFA:0000328 is_a: UBERON:0001015 {source="MA"} ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0007811 {source="MA"} ! craniocervical region property_value: UBPROP:0000012 "in MA this is restricted to skeletal muscles" xsd:string {external_ontology="MA"} [Term] id: UBERON:0008231 name: dorsal thoracic segment of trunk namespace: uberon def: "Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax." [FMA:24217] synonym: "back of thorax" RELATED [FMA:24217] synonym: "dorsum of thorax" EXACT [FMA:24217] synonym: "posterior part of thorax" EXACT [FMA:24217] synonym: "thoracic back" EXACT [FMA:24217] synonym: "thoracic part of back" EXACT [FMA:24217] synonym: "upper back" EXACT [MA:0000028] xref: EMAPA:37234 {source="MA:th"} xref: FMA:24217 xref: MA:0000028 xref: SCTID:362666008 is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000915 {source="FMA", source="MA"} ! thoracic segment of trunk relationship: part_of UBERON:0011270 {source="FMA"} ! dorsal trunk [Term] id: UBERON:0008242 name: lower back muscle namespace: uberon def: "A muscle of back that is part of a lower back." [OBOL:automatic] xref: EMAPA:37262 {source="MA:th"} xref: MA:0000502 xref: SCTID:317178000 is_a: UBERON:0002324 ! muscle of back is_a: UBERON:0003833 {source="MA"} ! abdominal segment muscle intersection_of: UBERON:0002324 ! muscle of back intersection_of: part_of UBERON:0005462 ! lower back relationship: part_of UBERON:0005462 {source="MA"} ! lower back [Term] id: UBERON:0008243 name: upper back muscle namespace: uberon def: "A muscle of back that is part of a dorsal thoracic segment of trunk." [OBOL:automatic] xref: EMAPA:37261 {source="MA:th"} xref: MA:0000508 xref: SCTID:305071003 is_a: UBERON:0002324 ! muscle of back is_a: UBERON:0003830 {source="MA"} ! thoracic segment muscle intersection_of: UBERON:0002324 ! muscle of back intersection_of: part_of UBERON:0008231 ! dorsal thoracic segment of trunk relationship: part_of UBERON:0008231 {source="MA"} ! dorsal thoracic segment of trunk [Term] id: UBERON:0008255 name: right clavicle namespace: uberon def: "A clavicle that is in the right side of a entire appendicular skeleton." [OBOL:automatic] xref: FMA:13322 is_a: UBERON:0001105 {source="FMA"} ! clavicle bone intersection_of: UBERON:0001105 ! clavicle bone intersection_of: in_right_side_of UBERON:0002091 ! appendicular skeleton relationship: in_right_side_of UBERON:0002091 ! appendicular skeleton property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0008256 name: left clavicle namespace: uberon def: "A clavicle that is in the left side of a entire appendicular skeleton." [OBOL:automatic] xref: FMA:13323 is_a: UBERON:0001105 {source="FMA"} ! clavicle bone intersection_of: UBERON:0001105 ! clavicle bone intersection_of: in_left_side_of UBERON:0002091 ! appendicular skeleton relationship: in_left_side_of UBERON:0002091 ! appendicular skeleton property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0008266 name: periodontal ligament namespace: uberon def: "The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket[BTO]." [BTO:0001020, https://github.com/obophenotype/uberon/issues/1233, https://github.com/obophenotype/uberon/issues/21, Wikipedia:Periodontal_fiber] subset: pheno_slim synonym: "alveolar periosteum" RELATED [BTO:0001020] synonym: "alveolodental ligament" RELATED [BTO:0001020] synonym: "alveolodental membrane" RELATED [BTO:0001020] synonym: "desmodontium" RELATED [BTO:0001020, http://www.drugs.com/dict/desmodentium.html] synonym: "fibra periodontalis" EXACT LATIN [Wikipedia:Periodontal_ligament] synonym: "odontoperiosteum" RELATED [BTO:0001020] synonym: "paradentium" RELATED [BTO:0001020] synonym: "PDL" RELATED [Wikipedia:Periodontal_ligament] synonym: "peridental membrane" RELATED [BTO:0001020] synonym: "peridontal fiber" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal fibre" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal ligament" RELATED [] synonym: "peridontal ligament fiber" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal ligament fibre" RELATED [http://www.drugs.com/dict/desmodentium.html] synonym: "peridontal membrane" RELATED [BTO:0001020] synonym: "peridontium" RELATED [BTO:0001020] synonym: "periodontal fiber" EXACT LATIN [Wikipedia:Periodontal_ligament] synonym: "periodontal fibre" EXACT LATIN [Wikipedia:Periodontal_ligament] synonym: "periodontium" RELATED INCONSISTENT [FMA:56665] xref: BTO:0001020 xref: CALOHA:TS-0763 xref: EMAPA:35679 xref: FMA:56665 xref: GAID:1259 xref: MA:0002467 xref: MESH:D010513 xref: SCTID:245775004 xref: Wikipedia:Periodontal_fiber is_a: UBERON:0008846 {source="FMA-moved"} ! skeletal ligament is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001758 ! periodontium relationship: develops_from UBERON:0008969 {source="PMID:19767574", source="Wikipedia:Dental_follicle"} ! dental follicle relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/tmeehan relationship: part_of UBERON:0001758 {source="BTO"} ! periodontium property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/d/dc/The_Periodontium.jpg" xsd:anyURI property_value: seeAlso FMA:76870 property_value: UBPROP:0000001 "The collagen fibers, running from the cementum to the alveolar bone, that suspend a tooth in its socket; they include apical, oblique, horizontal, and alveolar crest fibers, indicating that the orientation of the fibers varies at different levels[http://www.drugs.com/dict/desmodentium.html]." xsd:string {source="http://www.drugs.com/dict/desmodentium.html"} property_value: UBPROP:0000001 "The fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone. It extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket[BTO]. It consist of cells, extracellular compartment of fibers. The cells are fibroblast, epithelial, undifferentiated mesenchymal cells, bone and cementum cells. The extracellular compartment consists of collagen fibers bundles embedded in ground substance. The PDL substance has been estimated to be 70% water and is thought to have a significant effect on the tooth's ability to withstand stress loads[WP][BTO:0001020, Wikipedia:Periodontal_fiber, https://github.com/obophenotype/uberon/issues/21]." xsd:string {source="Wikipedia:Periodontal_fiber"} property_value: UBPROP:0000012 "FMA treats periodontium and periodontal ligament as the same; it has a separate class desmodentium, which we place here even though it is classified as fetal in FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0008281 name: tooth bud namespace: uberon def: "A knoblike tooth primordium that develops into the mature tooth and consists of enamel organ, dental papilla, and dental sac enclosing them." [http://medical-dictionary.thefreedictionary.com/tooth+germ, UBERON:cjm] synonym: "dental bud" EXACT [FMA:306006] synonym: "dental germ" EXACT [http://medical-dictionary.thefreedictionary.com/tooth+germ] synonym: "tooth germ" EXACT [Wikipedia:Tooth_development] xref: BTO:0001838 xref: FMA:306006 xref: MESH:D014083 xref: NCIT:C34313 xref: SCTID:53301001 xref: UMLS:C0040442 {source="ncithesaurus:Tooth_Bud"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure relationship: develops_from UBERON:0005087 ! tooth placode relationship: part_of UBERON:0011595 {gci_relation="part_of", gci_filler="NCBITaxon:40674"} ! jaw region [Term] id: UBERON:0008307 name: heart endothelium namespace: uberon def: "An endothelium that is part of a heart [Automatically generated definition]." [OBOL:automatic] synonym: "cardiac endothelium" RELATED [BTO:0004293] xref: BTO:0004293 is_a: UBERON:0004852 ! cardiovascular system endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: IAO:0000232 "this class includes any endothelia that are part of the heart. This might include the endocardial epithelia, as well as endothelia of vessels that are considered strictly part of the heart (e.g. outflow tract). As a grouping class, this may lack utility, and pending review this class may be obsoleted. For annotation consider a more specific class." xsd:string [Term] id: UBERON:0008310 name: nasopharyngeal gland namespace: uberon def: "A gland that is part of a nasopharynx." [OBOL:automatic] subset: organ_slim xref: FMA:55076 xref: SCTID:178973008 is_a: UBERON:0003295 ! pharyngeal gland is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001728 ! nasopharynx [Term] id: UBERON:0008324 name: erectile tissue namespace: uberon def: "With numerous vascular spaces that may become engorged with blood." [Wikipedia:Erectile_tissue] comment: Examples: corpus cavernosum or penis or clitoris xref: Wikipedia:Erectile_tissue is_a: UBERON:0000479 ! tissue relationship: only_in_taxon NCBITaxon:33213 ! Bilateria [Term] id: UBERON:0008331 name: clitoral smooth muscle namespace: uberon def: "A smooth muscle tissue that is part of a clitoris." [OBOL:automatic] synonym: "clitoris smooth muscle" RELATED [BTO:0005000] xref: BTO:0005000 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002411 ! clitoris relationship: part_of UBERON:0002411 ! clitoris [Term] id: UBERON:0008339 name: microvascular endothelium namespace: uberon xref: BTO:0003122 is_a: UBERON:0004638 ! blood vessel endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:8410081 ! blood microvessel relationship: part_of UBERON:8410081 ! blood microvessel property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2186" xsd:string [Term] id: UBERON:0008342 name: intestinal villus of duodenum namespace: uberon def: "An intestinal villus in the duodenum." [OBOL:automatic] xref: FMA:63300 is_a: UBERON:0001213 ! intestinal villus intersection_of: UBERON:0001213 ! intestinal villus intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0000320 ! duodenal mucosa [Term] id: UBERON:0008346 name: duodenal epithelium namespace: uberon def: "An epithelium that is part of a duodenum." [OBOL:automatic] subset: human_reference_atlas synonym: "epithelium of duodenum" EXACT [FMA:17231] xref: CALOHA:TS-2087 xref: EMAPA:19078 xref: FMA:17231 xref: MA:0003208 xref: SCTID:66036002 is_a: UBERON:0013636 ! epithelium of intestinal villus intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0008342 {source="FMA"} ! intestinal villus of duodenum property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0008397 name: tracheobronchial epithelium namespace: uberon def: "Epithelium pertaining to the trachea and bronchi." [Dorlands_Medical_Dictionary:MerckMedicus] synonym: "bronchotracheal epithelium" RELATED [BTO:0002925] xref: BTO:0002925 xref: CALOHA:TS-1063 is_a: UBERON:0004815 ! lower respiratory tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0007196 ! tracheobronchial tree relationship: part_of UBERON:0007196 ! tracheobronchial tree [Term] id: UBERON:0008429 name: cervical vertebral foramen namespace: uberon def: "A vertebral foramen that is part of a cervical vertebra." [OBOL:automatic] xref: FMA:13480 xref: SCTID:280833008 is_a: UBERON:0001131 ! vertebral foramen is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0002413 ! cervical vertebra [Term] id: UBERON:0008430 name: lumbar vertebral foramen namespace: uberon def: "A vertebral foramen that is part of a lumbar vertebra." [OBOL:automatic] xref: FMA:24826 xref: SCTID:280835001 is_a: UBERON:0001131 ! vertebral foramen is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0002414 ! lumbar vertebra relationship: part_of UBERON:0002414 ! lumbar vertebra [Term] id: UBERON:0008431 name: sacral foramen namespace: uberon def: "A vertebral foramen that is part of a sacral vertebra." [OBOL:automatic] xref: FMA:31749 is_a: UBERON:0001131 ! vertebral foramen is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0001094 ! sacral vertebra relationship: part_of UBERON:0001094 ! sacral vertebra [Term] id: UBERON:0008432 name: thoracic vertebral foramen namespace: uberon def: "A vertebral foramen that is part of a thoracic vertebra." [OBOL:automatic] xref: FMA:9143 xref: SCTID:280834002 is_a: UBERON:0001131 ! vertebral foramen is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0001131 ! vertebral foramen intersection_of: part_of UBERON:0002347 ! thoracic vertebra relationship: part_of UBERON:0002347 ! thoracic vertebra [Term] id: UBERON:0008433 name: lumbar vertebral arch namespace: uberon def: "A neural arch that is part of a lumbar vertebra." [OBOL:automatic] synonym: "arch of lumbar vertebra" EXACT [FMA:16076] xref: FMA:16076 xref: SCTID:312766000 is_a: UBERON:0003828 ! abdominal segment bone is_a: UBERON:0003861 ! neural arch is_a: UBERON:0004247 ! bone of dorsum intersection_of: UBERON:0003861 ! neural arch intersection_of: part_of UBERON:0002414 ! lumbar vertebra relationship: part_of UBERON:0002414 ! lumbar vertebra [Term] id: UBERON:0008434 name: cervical vertebral arch namespace: uberon def: "A neural arch that is part of a cervical vertebra." [OBOL:automatic] synonym: "arch of cervical vertebra" EXACT [FMA:23893] xref: FMA:23893 xref: SCTID:165269004 is_a: UBERON:0003458 ! neck bone is_a: UBERON:0003861 ! neural arch is_a: UBERON:0004247 ! bone of dorsum intersection_of: UBERON:0003861 ! neural arch intersection_of: part_of UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0002413 ! cervical vertebra [Term] id: UBERON:0008435 name: vertebral arch of sacral segment namespace: uberon def: "A neural arch that is part of a sacral vertebra." [OBOL:automatic] xref: FMA:32401 is_a: UBERON:0003828 ! abdominal segment bone is_a: UBERON:0003861 ! neural arch is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0005179 ! pelvic region element intersection_of: UBERON:0003861 ! neural arch intersection_of: part_of UBERON:0001094 ! sacral vertebra relationship: part_of UBERON:0001094 ! sacral vertebra [Term] id: UBERON:0008436 name: thoracic vertebral arch namespace: uberon def: "A neural arch that is part of a thoracic vertebra." [OBOL:automatic] synonym: "arch of thoracic vertebra" EXACT [FMA:9151] xref: FMA:9151 xref: SCTID:312764002 is_a: UBERON:0003827 ! thoracic segment bone is_a: UBERON:0003861 ! neural arch is_a: UBERON:0004247 ! bone of dorsum intersection_of: UBERON:0003861 ! neural arch intersection_of: part_of UBERON:0002347 ! thoracic vertebra relationship: part_of UBERON:0002347 ! thoracic vertebra [Term] id: UBERON:0008447 name: intertarsal joint namespace: uberon def: "Intertarsal articulations are the joints of the tarsus. The specific intertarsal articulations are: Talocalcaneal articulation Talocalcaneonavicular articulation Calcaneocuboid articulation Cuneonavicular articulation Cuboideonavicular articulation Intercuneiform articulation Cuneocuboid articulation." [Wikipedia:Intertarsal_articulations] synonym: "articulationes intertarsale" RELATED [MESH:A02.835.583.378.831] synonym: "articulationes intertarsales" RELATED LATIN [Wikipedia:Intertarsal_articulations] synonym: "articulationes intertarseae" RELATED [MESH:A02.835.583.378.831] synonym: "intermetatarsal joint" RELATED [MESH:A02.835.583.378.831] synonym: "intertarsal" RELATED [Wikipedia:Intertarsal_articulations] synonym: "intertarsal articulation" RELATED [Wikipedia:Intertarsal_articulations] synonym: "intertarsal joint" RELATED [MESH:A02.835.583.378.831] synonym: "tarsal joint" RELATED [MESH:A02.835.583.378.831] synonym: "tarsal joints" RELATED [Wikipedia:Intertarsal_articulations] xref: EMAPA:37762 {source="MA:th"} xref: FMA:44281 xref: GAID:259 xref: MA:0003112 xref: MESH:D013640 xref: NCIT:C33735 xref: SCTID:182221001 xref: SCTID:361283005 xref: UMLS:C1527245 {source="ncithesaurus:Tarsal_Joint"} xref: Wikipedia:Intertarsal_articulations is_a: UBERON:0001487 ! pes joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001447 {cardinality="2"} ! tarsal bone relationship: connects UBERON:0001447 {notes="two adjacent tarsals"} ! tarsal bone relationship: part_of UBERON:0004454 ! tarsal region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray360.png" xsd:anyURI [Term] id: UBERON:0008456 name: prezygapophysis of lumbar vertebra namespace: uberon def: "A prezygapophysis that is part of a lumbar vertebra." [OBOL:automatic] synonym: "cranial articular process of lumbar vertebra" EXACT [FMA:16126] synonym: "superior articular process of lumbar vertebra" EXACT HUMAN_PREFERRED [FMA:16126] xref: FMA:16126 xref: SCTID:305677003 is_a: UBERON:0001079 ! prezygapophysis intersection_of: UBERON:0001079 ! prezygapophysis intersection_of: part_of UBERON:0002414 ! lumbar vertebra relationship: part_of UBERON:0002414 ! lumbar vertebra [Term] id: UBERON:0008457 name: prezygapophysis of sacral vertebra namespace: uberon def: "A prezygapophysis that is part of a sacral vertebra." [OBOL:automatic] synonym: "articular process of sacral segment" EXACT [FMA:16215] synonym: "processus articularis superior (os sacrum)" EXACT [FMA:16215] synonym: "processus articularis superior ossis sacri" EXACT LATIN [FMA:TA] synonym: "superior articular process of sacral segment" EXACT [FMA:16215] synonym: "superior articular process of sacral vertebra" EXACT HUMAN_PREFERRED [FMA:16215] synonym: "superior articular process of sacrum" EXACT [FMA:16215] xref: FMA:16215 is_a: UBERON:0001079 ! prezygapophysis intersection_of: UBERON:0001079 ! prezygapophysis intersection_of: part_of UBERON:0001094 ! sacral vertebra relationship: part_of UBERON:0001094 ! sacral vertebra [Term] id: UBERON:0008459 name: prezygapophysis of cervical vertebra namespace: uberon def: "A prezygapophysis that is part of a cervical vertebra." [OBOL:automatic] synonym: "superior articular process of cervical segment" EXACT [] synonym: "superior articular process of cervical vertebra" EXACT HUMAN_PREFERRED [FMA:23969] xref: FMA:23969 xref: SCTID:57767002 is_a: UBERON:0001079 ! prezygapophysis intersection_of: UBERON:0001079 ! prezygapophysis intersection_of: part_of UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0002413 ! cervical vertebra [Term] id: UBERON:0008460 name: prezygapophysis of thoracic vertebra namespace: uberon def: "A prezygapophysis that is part of a thoracic vertebra." [OBOL:automatic] synonym: "cranial articular process of thoracic vertebra" EXACT [FMA:9155] synonym: "processus articularis (zygapophysis) thoracicus superior" EXACT [FMA:9155] synonym: "superior apophyseal process" EXACT [FMA:9155] synonym: "superior articular process of thoracic vertebra" EXACT HUMAN_PREFERRED [FMA:9155] synonym: "superior zygapophysis" RELATED [FMA:9155] xref: FMA:9155 xref: SCTID:367801006 is_a: UBERON:0001079 ! prezygapophysis intersection_of: UBERON:0001079 ! prezygapophysis intersection_of: part_of UBERON:0002347 ! thoracic vertebra relationship: part_of UBERON:0002347 ! thoracic vertebra [Term] id: UBERON:0008461 name: postzygapophysis of lumbar vertebra namespace: uberon def: "An postzygapophysis that is part of a lumbar vertebra." [OBOL:automatic] synonym: "caudal articular process of lumbar vertebra" EXACT [FMA:16127] synonym: "inferior articular process of lumbar vertebra" EXACT HUMAN_PREFERRED [FMA:16127] xref: FMA:16127 xref: SCTID:306283004 is_a: UBERON:0001080 ! postzygapophysis intersection_of: UBERON:0001080 ! postzygapophysis intersection_of: part_of UBERON:0002414 ! lumbar vertebra relationship: part_of UBERON:0002414 ! lumbar vertebra [Term] id: UBERON:0008462 name: postzygapophysis of cervical vertebra namespace: uberon def: "An postzygapophysis that is part of a cervical vertebra." [OBOL:automatic] synonym: "inferior articular process of cervical vertebra" EXACT HUMAN_PREFERRED [FMA:23970] xref: FMA:23970 xref: SCTID:61633005 is_a: UBERON:0001080 ! postzygapophysis intersection_of: UBERON:0001080 ! postzygapophysis intersection_of: part_of UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0002413 ! cervical vertebra [Term] id: UBERON:0008463 name: postzygapophysis of thoracic vertebra namespace: uberon def: "An postzygapophysis that is part of a thoracic vertebra." [OBOL:automatic] synonym: "caudal articular process of thoracic vertebra" EXACT [FMA:9156] synonym: "inferior apophyseal process" EXACT [FMA:9156] synonym: "inferior articular process of thoracic vertebra" EXACT HUMAN_PREFERRED [FMA:9156] synonym: "inferior zygapophysis" EXACT [FMA:9156] synonym: "processus articularis (zygapophysis) thoracicus inferior" EXACT [FMA:9156] xref: FMA:9156 xref: SCTID:367814007 is_a: UBERON:0001080 ! postzygapophysis intersection_of: UBERON:0001080 ! postzygapophysis intersection_of: part_of UBERON:0002347 ! thoracic vertebra relationship: part_of UBERON:0002347 ! thoracic vertebra [Term] id: UBERON:0008522 name: nasal muscle namespace: uberon def: "Any muscle organ that is part of an nose." [OBOL:automatic] synonym: "muscle of nose" EXACT [OBOL:automatic] xref: FMA:73758 xref: NCIT:C33158 xref: SCTID:244730009 xref: UMLS:C0224219 {source="ncithesaurus:Nasal_Muscle"} is_a: UBERON:0001577 {source="FMA"} ! facial muscle is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000004 ! nose relationship: part_of UBERON:0000004 ! nose [Term] id: UBERON:0008713 name: pectoral girdle and thoracic body wall skeletal muscle namespace: uberon xref: EHDAA2:0001421 xref: EMAPA:17748 xref: RETIRED_EHDAA2:0001422 is_a: UBERON:0001134 ! skeletal muscle tissue [Term] id: UBERON:0008772 name: proximal epiphysis of tibia namespace: uberon def: "A proximal epiphysis that is part of a tibia." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "head of tibia" EXACT [FMA:33113] synonym: "proximal end of tibia" EXACT [FMA:33113] synonym: "proximal tibial epiphysis" EXACT [] synonym: "upper end of tibia" EXACT [FMA:33113] xref: FMA:33113 xref: NCIT:C32722 xref: SCTID:302526005 xref: UMLS:C0932431 {source="ncithesaurus:Head_of_the_Tibia"} xref: Wikipedia:Upper_extremity_of_tibia is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004383 ! epiphysis of tibia intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0000979 ! tibia property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0008775 name: proximal epiphysis of fibula namespace: uberon def: "A proximal epiphysis that is part of a fibula." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "caput fibulae" EXACT LATIN [Wikipedia:Head_of_fibula] synonym: "fibular head" RELATED [FMA:33729] synonym: "head of fibula" EXACT [FMA:33729] synonym: "proximal end of fibula" EXACT [FMA:33729] synonym: "upper end of fibula" EXACT [FMA:33729] xref: EMAPA:37890 {source="MA:th"} xref: FMA:33729 xref: galen:HeadOfFibula xref: NCIT:C32719 xref: SCTID:182080006 xref: UMLS:C0223908 {source="ncithesaurus:Head_of_the_Fibula"} xref: Wikipedia:Head_of_fibula is_a: UBERON:0004380 ! proximal epiphysis is_a: UBERON:0004388 ! epiphysis of fibula intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001446 ! fibula property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The upper extremity or head of the fibula is of an irregular quadrate form, presenting above a flattened articular surface, directed upward, forward, and medialward, for articulation with a corresponding surface on the lateral condyle of the tibia. On the lateral side is a thick and rough prominence continued behind into a pointed eminence, the apex, which projects upward from the posterior part of the head. The prominence, at its upper and lateral part, gives attachment to the tendon of the Biceps femoris and to the fibular collateral ligament of the knee-joint, the ligament dividing the tendon into two parts. The remaining part of the circumference of the head is rough, for the attachment of muscles and ligaments. It presents in front a tubercle for the origin of the upper and anterior fibers of the Peronæus longus, and a surface for the attachment of the anterior ligament of the head; and behind, another tubercle, for the attachment of the posterior ligament of the head and the origin of the upper fibers of the Soleus[Wikipedia:Head_of_fibula]." xsd:string {source="Wikipedia:Head_of_fibula"} [Term] id: UBERON:0008780 name: inner cell mass derived epiblast namespace: uberon def: "An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers." [MP:0003886] comment: The epiblast cells (appearing on day 8 of human embryonic development) make up a columnar epithelium with dense microvilli on the apical surface. During gastrulation, the epiblast cells undergo epithelial-to-mesenchymal transition and delaminate to become the loose mesenchyme of the primitive streak. The epiblast is present in postimplantation mouse embryos between E5.5-E7.5. subset: early_development subset: pheno_slim synonym: "embryonic epiblast" RELATED [MP:0003886] xref: EHDAA2:0000444 xref: EHDAA:42 xref: EHDAA:75 xref: EMAPA:16050 xref: NCIT:C34164 xref: UMLS:C1516906 {source="ncithesaurus:Epiblast"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002532 ! epiblast (generic) intersection_of: UBERON:0002532 ! epiblast (generic) intersection_of: develops_from UBERON:0000087 ! inner cell mass relationship: develops_from UBERON:0000087 {source="Wikipedia"} ! inner cell mass relationship: part_of UBERON:0000091 ! bilaminar disc [Term] id: UBERON:0008783 name: dorsal venous arch namespace: uberon def: "The dorsal venous arch of the foot is a superficial vein that connects the small saphenous vein and the great saphenous vein. Anatomically, it is defined by where the dorsal veins of the first and fifth digit, respectively, meet the great saphenous vein and small saphenous vein." [Wikipedia:Dorsal_venous_arch_of_the_foot] subset: human_reference_atlas synonym: "arcus venosus dorsalis pedis" EXACT [Wikipedia:Dorsal_venous_arch_of_the_foot] synonym: "arcus venosus dorsalis pedis" RELATED LATIN [Wikipedia:Dorsal_venous_arch_of_the_foot] synonym: "dorsal venous arch of foot" EXACT [FMA:44356] xref: EMAPA:37521 {source="MA:th"} xref: FMA:44356 xref: MA:0002110 xref: SCTID:231189006 xref: Wikipedia:Dorsal_venous_arch_of_the_foot is_a: UBERON:0001638 {source="MA"} ! vein relationship: connected_to UBERON:0001545 ! anterior tibial vein relationship: connected_to UBERON:0001547 ! small saphenous vein relationship: connected_to UBERON:0001550 ! medial marginal vein relationship: part_of RO:0002577 ! system property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4e/Gray581.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0008784 name: lower limb segment namespace: uberon def: "A limb segment that is part of a hindlimb." [OBOL:automatic] synonym: "free lower limb segment" EXACT [FMA:24877] synonym: "free lower limb subdivision" EXACT [FMA:24877] synonym: "segment of free lower limb" EXACT [FMA:24877] synonym: "subdivision of free lower limb" EXACT [FMA:24877] xref: FMA:24877 is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 ! limb segment intersection_of: part_of UBERON:0002103 ! hindlimb relationship: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0008785 name: upper limb segment namespace: uberon def: "A limb segment that is part of a forelimb." [OBOL:automatic] synonym: "free upper limb segment" EXACT [FMA:24876] synonym: "free upper limb subdivision" EXACT [FMA:24876] synonym: "segment of free upper limb" EXACT [FMA:24876] synonym: "subdivision of free upper limb" EXACT [FMA:24876] xref: FMA:24876 is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 ! limb segment intersection_of: part_of UBERON:0002102 ! forelimb relationship: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0008789 name: cranial fossa namespace: uberon def: "Any of the three large depressions in the posterior, middle, and anterior aspects of the floor of the cranial cavity." [http://mw1.merriam-webster.com/medical/cranial%20fossa] xref: FMA:321144 is_a: UBERON:0004704 ! bone fossa intersection_of: UBERON:0004704 ! bone fossa intersection_of: part_of UBERON:0003128 ! cranium relationship: part_of UBERON:0004766 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! cranial bone property_value: editor_note "todo - review the relationships for this and its subclasses; the relation should be bounded rather than part of, and contains should be used for the brain parts contained by the fossae" xsd:string [Term] id: UBERON:0008805 name: gingival groove namespace: uberon def: "The gingival sulcus is an area of potential space between a tooth and the surrounding gingival tissue and is lined by sulcular epithelium. The depth of the sulcus (Latin for groove) is bounded by two entities: apically by the gingival fibers of the connective tissue attachment and coronally by the free gingival margin." [Wikipedia:Gingival_sulcus] synonym: "gingival sulcus" EXACT [FMA:74580] synonym: "sulcus gingivalis" EXACT LATIN [FMA:TA] synonym: "sulcus gingivalis" RELATED LATIN [Wikipedia:Gingival_sulcus] synonym: "tooth-gingiva interface" EXACT [] xref: FMA:74580 xref: NCIT:C114645 xref: SCTID:245753001 xref: Wikipedia:Gingival_sulcus is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000093 ! sulcus intersection_of: UBERON:0000093 ! sulcus intersection_of: adjacent_to UBERON:0001091 ! calcareous tooth intersection_of: adjacent_to UBERON:0001828 ! gingiva relationship: adjacent_to UBERON:0001091 ! calcareous tooth relationship: adjacent_to UBERON:0001828 ! gingiva relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000165 ! mouth property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/5/5e/Gingival_sulcus.PNG" xsd:anyURI [Term] id: UBERON:0008810 name: nasopalatine nerve namespace: uberon def: "A branch of that maxillary nerve that innervates the mucous membrane of the hard palate." [http://medical-dictionary.thefreedictionary.com/nasopalatine+nerve, UBERON:cjm] synonym: "naso-palatine nerve" RELATED [Wikipedia:Nasopalatine_nerve] synonym: "nasopalatine" RELATED [Wikipedia:Nasopalatine_nerve] synonym: "nasopalatine nerves" RELATED [Wikipedia:Nasopalatine_nerve] synonym: "nervus nasopalatinus" RELATED LATIN [Wikipedia:Nasopalatine_nerve] synonym: "Scarpa's nerve" EXACT [FMA:52797] xref: BAMS:npal xref: FMA:52797 xref: Wikipedia:Nasopalatine_nerve is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0011779 ! nerve of head region intersection_of: UBERON:0001021 ! nerve intersection_of: branching_part_of UBERON:0000377 ! maxillary nerve intersection_of: innervates UBERON:0005046 ! mucosa of hard palate relationship: branching_part_of UBERON:0000377 ! maxillary nerve relationship: innervates UBERON:0005046 ! mucosa of hard palate relationship: part_of UBERON:0000377 ! maxillary nerve property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray858.png" xsd:anyURI [Term] id: UBERON:0008811 name: intromittent organ namespace: uberon def: "An external organ of a male organism that is specialized to deliver sperm during copulation. Intromittent organs are found most often in terrestrial species, as most aquatic species fertilize their eggs externally, although there are exceptions[WP]." [Wikipedia:Intromittent_organ] subset: grouping_class subset: organ_slim synonym: "aedeagus" NARROW SENSU [FBbt:00004850] synonym: "copulatory organ" RELATED [] synonym: "penis" NARROW [] xref: AAO:0010255 xref: FBbt:00004850 xref: HAO:0000091 xref: TAO:0002036 xref: TGMA:0000585 xref: Wikipedia:Intromittent_organ is_a: UBERON:0003135 ! male reproductive organ relationship: capable_of_part_of GO:0007620 ! copulation relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa property_value: IAO:0000232 "this is a broad grouping class connecting a number of different analagous organs by their function. We place the insect aedeagus here rather than penis, although this is somewhat arbitrary given the broadness of the current definition" xsd:string property_value: UBPROP:0000001 "Surface structure that is an external structure of a male organism through which sperm is transferred to a female organism during mating.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002036", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0008814 name: pharyngeal arch system namespace: uberon def: "A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]." [GO:0060037, GOC:dph] synonym: "embryonic pharyngeal complex" EXACT [] synonym: "pharyngeal apparatus" EXACT [] synonym: "pharyngeal arch complex" RELATED [] synonym: "pharyngeal arch region" RELATED [EHDAA2:0000187] synonym: "pharyngeal arches and clefts" RELATED [] synonym: "pharyngeal complex" RELATED [] synonym: "pharyngeal system" EXACT [GO:0060037] xref: EHDAA2:0000187 xref: FMA:293041 xref: NCIT:C34248 xref: UMLS:C1519038 {source="ncithesaurus:Pharyngeal_Apparatus"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034921 ! multi organ part structure relationship: only_in_taxon NCBITaxon:7711 ! Chordata relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0009145 ! pharyngeal region of foregut property_value: editor_note "Currently defined in a vertebrate specific manner. The arch system has origins in basal deuterostomes, consider generalizing" xsd:string [Term] id: UBERON:0008816 name: embryonic head namespace: uberon def: "A head that is part of a embryo." [OBOL:automatic] subset: non_informative xref: CALOHA:TS-0246 xref: FBbt:00000155 xref: FMA:293011 is_a: UBERON:0000033 ! head intersection_of: UBERON:0000033 ! head intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0008823 name: neural tube derived brain namespace: uberon def: "A brain that develops_from a neural tube." [https://github.com/obophenotype/uberon/issues/338, OBOL:automatic] synonym: "vertebrate brain" NARROW [] is_a: UBERON:0000489 {source="ZFA"} ! cavitated compound organ is_a: UBERON:0000955 ! brain intersection_of: UBERON:0000955 ! brain intersection_of: develops_from UBERON:0001049 ! neural tube relationship: develops_from UBERON:0001049 ! neural tube relationship: part_of UBERON:0000033 {source="FMA"} ! head property_value: editor_note "a reasoner should automatically classify all the vertebrate ontology brain classes here" xsd:string property_value: seeAlso "https://github.com/obophenotype/uberon/issues/338" xsd:anyURI [Term] id: UBERON:0008824 name: duct of epididymis namespace: uberon def: "Any duct branching of of the main epididymis duct." [http://orcid.org/0000-0002-6601-2165] synonym: "epididymal duct" EXACT [MA:0001735] synonym: "epididymis duct" EXACT [FMA:18297] xref: EMAPA:36525 xref: FMA:18297 xref: MA:0001735 xref: NCIT:C32484 xref: SCTID:279623004 xref: UMLS:C0458632 {source="ncithesaurus:Duct_of_the_Epididymis"} is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005904 ! duct of male reproductive system intersection_of: UBERON:0000058 ! duct intersection_of: branching_part_of UBERON:0001301 ! epididymis relationship: branching_part_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0001301 {source="FMA"} ! epididymis [Term] id: UBERON:0008828 name: presphenoid bone namespace: uberon def: "The anterior part of the body of the sphenoid bone in front of the basisphenoid. It is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult." [http://www.thefreedictionary.com/Presphenoid+bone, Wikipedia:Ossification_of_sphenoid#Presphenoid] subset: pheno_slim synonym: "presphenoidal bone" EXACT [] xref: EMAPA:36616 xref: FMA:321632 xref: MA:0001470 xref: SCTID:95949009 xref: Wikipedia:Ossification_of_sphenoid#Presphenoid is_a: UBERON:0002513 ! endochondral bone is_a: UBERON:0003462 ! facial bone is_a: UBERON:0011164 {source="MA"} ! neurocranium bone relationship: contributes_to_morphology_of UBERON:0001677 ! sphenoid bone relationship: part_of UBERON:0001677 {source="MA"} ! sphenoid bone relationship: part_of UBERON:0003111 {source="ISBN:0073040584"} ! sphenoid region property_value: editor_note "TODO - account for developmental change" xsd:string [Term] id: UBERON:0008835 name: hepatic diverticulum namespace: uberon def: "An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts." [http://www.stembook.org/node/512, MP:MP] subset: pheno_slim synonym: "diverticulum hepaticum" RELATED LATIN [Wikipedia:Hepatic_diverticulum] synonym: "liver diverticulum" EXACT [XAO:0000101] xref: AAO:0011057 xref: EHDAA2:0000740 xref: EHDAA:1530 xref: NCIT:C34187 xref: UMLS:C1512407 {source="ncithesaurus:Hepatic_Diverticulum"} xref: Wikipedia:Hepatic_diverticulum xref: XAO:0000101 is_a: UBERON:0004185 ! endodermal part of digestive tract is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac is_a: UBERON:0009497 ! epithelium of foregut-midgut junction is_a: UBERON:0009854 ! digestive tract diverticulum relationship: develops_from UBERON:0003894 {source="EHDAA2"} ! liver primordium relationship: part_of UBERON:0004161 {notes="caudal part", source="EHDAA2"} ! septum transversum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/4/4f/Gray1088.png" xsd:anyURI property_value: UBPROP:0000008 "in mice, the hepatic diverticulum forms by E9 and expands into an obvious liver bud by E10" xsd:string property_value: UBPROP:0000011 "The caudal part of the septum transversum is invaded by the hepatic diverticulum which divides within it to form the liver and thus gives rise to the ventral mesentery of the foregut." xsd:string [Term] id: UBERON:0008836 name: liver bud namespace: uberon xref: BTO:0001642 is_a: UBERON:0004185 ! endodermal part of digestive tract is_a: UBERON:0007499 {source="cjm"} ! epithelial sac is_a: UBERON:0009497 ! epithelium of foregut-midgut junction is_a: UBERON:0009854 ! digestive tract diverticulum relationship: develops_from UBERON:0008835 {source="http://www.stembook.org/node/512"} ! hepatic diverticulum [Term] id: UBERON:0008845 name: nonskeletal ligament namespace: uberon def: "A ligament that does not connect two skeletal elements." [http://orcid.org/0000-0002-6601-2165] synonym: "fibrous ligament" RELATED [Wikipedia:Ligament] synonym: "non-skeletal ligament" EXACT [] xref: FMA:25625 xref: MA:0003004 xref: SCTID:410746001 is_a: UBERON:0000211 {source="cjm"} ! ligament disjoint_from: UBERON:0008846 ! skeletal ligament property_value: UBPROP:0000001 "Ligament organ that primarily consists of dense connective tissue aggregated into fasciculi which may be admixed with smooth muscle. Examples: ligament of liver, ovarian ligament[FMA:25625]." xsd:string {source="FMA:25625"} property_value: UBPROP:0000012 "this class is used more generally than the FMA class, to include for example folds of mesentery such as the broad ligament of the uterus." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0008846 name: skeletal ligament namespace: uberon def: "Dense regular connective tissue connecting two or more adjacent skeletal elements[VSAO,modified]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165] synonym: "articular larua" EXACT [Wikipedia:Ligament] synonym: "articular ligament" EXACT [Wikipedia:Ligament] synonym: "ligament" BROAD [VSAO:0000072, ZFA:0001675] synonym: "true ligament" EXACT [Wikipedia:Ligament] xref: AAO:0010444 xref: AEO:0000090 xref: CALOHA:TS-2146 xref: EHDAA2:0003232 xref: EV:0100144 xref: FMA:25624 xref: GAID:118 xref: MA:0003005 xref: SCTID:410744003 xref: VSAO:0000072 xref: Wikipedia:Ligament#Articular_ligaments is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000211 ! ligament intersection_of: UBERON:0000211 ! ligament intersection_of: connects UBERON:0004765 ! skeletal element intersection_of: part_of UBERON:0001434 ! skeletal system relationship: composed_primarily_of UBERON:0007846 {source="VSAO"} ! dense regular connective tissue relationship: connects UBERON:0004765 {notes="bones or cartilage organs"} ! skeletal element relationship: has_part CL:0000057 {source="AEO"} ! fibroblast relationship: has_part CL:0000327 {source="AEO"} ! extracellular matrix secreting cell relationship: part_of UBERON:0001434 ! skeletal system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/9a/Knee_diagram.svg" xsd:anyURI property_value: editor_note "logical definition deliberately made strict to avoid classifying MA:spiral ligament as both nonskeletal and skeletal. see https://github.com/obophenotype/mouse-anatomy-ontology/issues/71" xsd:string property_value: UBPROP:0000001 "Dense regular connective tissue connecting two or more adjacent skeletal elements or supporting an organ.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000072", ontology="VSAO", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Ligament organ that primarily consists of regular dense connective tissue aggregated into fasciculi; connects bone and cartilage organs. Examples: sutural ligament, ligament of pinna, tarsal ligament[FMA:25624]." xsd:string {source="FMA:25624"} [Term] id: UBERON:0008856 name: stomach muscularis externa namespace: uberon def: "The smooth muscle layer of the stomach wall that functions to churn and mix food and gastric secretions as well as to move food along the digestive tract to the intestines." [MP:0010779] subset: pheno_slim synonym: "gastric muscularis" EXACT [FMA:14909] synonym: "muscle layer of stomach" EXACT [FMA:14909] synonym: "muscularis externa of stomach" EXACT [FMA:14909] synonym: "tunica muscularis (gaster)" EXACT [FMA:14909] synonym: "tunica muscularis gastris" EXACT [] xref: FMA:14909 xref: SCTID:362132003 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0018261 ! muscular coat of digestive tract is_a: UBERON:0034933 ! layer of smooth muscle tissue intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001167 ! wall of stomach relationship: contributes_to_morphology_of UBERON:0001135 ! smooth muscle tissue relationship: contributes_to_morphology_of UBERON:0001167 ! wall of stomach relationship: part_of UBERON:0004222 {source="MA-abduced"} ! stomach smooth muscle property_value: UBPROP:0000010 "the muscularis externa in the stomach differs from that of other GI organs in that it has three layers of smooth muscle instead of two" xsd:string {source="WP"} [Term] id: UBERON:0008858 name: pyloric canal namespace: uberon def: "The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter." [MP:0010791, Wikipedia:Pyloric_canal] subset: pheno_slim synonym: "canalis pyloricus" EXACT [Wikipedia:Pyloric_canal] synonym: "canalis pyloricus" RELATED LATIN [Wikipedia:Pyloric_canal] xref: EMAPA:37944 {source="MA:th"} xref: FMA:14580 xref: SCTID:245417002 xref: Wikipedia:Pyloric_canal is_a: UBERON:0009870 {source="FMA"} ! zone of stomach relationship: continuous_with UBERON:0001165 ! pyloric antrum relationship: continuous_with UBERON:0001202 ! pyloric sphincter relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus relationship: part_of UBERON:0001166 {source="Wikipedia"} ! pylorus property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/3/33/Illu_stomach.jpg" xsd:anyURI [Term] id: UBERON:0008861 name: pyloric gastric gland namespace: uberon def: "The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]." [MP:0010797, Wikipedia:Pyloric_gland] subset: pheno_slim synonym: "glandula pylorica" EXACT [FMA:14922] synonym: "pyloric antrum gland" EXACT [OBOL:automatic] synonym: "pyloric gland" EXACT [FMA:14922] synonym: "pyloric mucuous gland" EXACT [] xref: EMAPA:27211 xref: FMA:14922 xref: NCIT:C33431 xref: SCTID:70710007 xref: UMLS:C0227239 {source="ncithesaurus:Pyloric_Gland"} xref: Wikipedia:Pyloric_gland is_a: UBERON:0000325 ! gastric gland is_a: UBERON:0000414 {source="MP"} ! mucous gland intersection_of: UBERON:0000325 ! gastric gland intersection_of: part_of UBERON:0001166 ! pylorus relationship: contributes_to_morphology_of UBERON:0001166 ! pylorus relationship: has_quality PATO:0002299 {source="Wikipedia:Tubular_gland"} ! tubular relationship: part_of UBERON:0004998 ! mucosa of pylorus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/bf/Gray1054.png" xsd:anyURI property_value: editor_note "check relationship to pylorus vs antrum" xsd:string [Term] id: UBERON:0008876 name: hypodermis skeletal muscle layer namespace: uberon alt_id: UBERON:0010934 def: "Any skeletal muscle organ in the hypodermis / superficial fascia." [ISBN:0123813611, MP:0011157] subset: pheno_slim synonym: "hypodermal muscle layer" EXACT [MP:0011157] synonym: "hypodermis muscle layer" EXACT [MP:0011157] synonym: "panniculus carnosus" NARROW [MP:0011157] synonym: "superficial fascia muscular layer" EXACT [] xref: EMAPA:18188 xref: MA:0003140 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004253 ! skin muscle is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0002072 ! hypodermis relationship: contributes_to_morphology_of UBERON:0001015 ! musculature relationship: contributes_to_morphology_of UBERON:0002072 ! hypodermis relationship: has_muscle_insertion UBERON:0002097 ! skin of body relationship: located_in UBERON:0002190 {source="MP-def"} ! subcutaneous adipose tissue relationship: part_of UBERON:0002072 ! hypodermis property_value: editor_note "We follow MP and treat this as part of the hypodermis, although some sources may consider the hypodermis to be superficial to this" xsd:string [Term] id: UBERON:0008883 name: osteoid namespace: uberon def: "Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000046] subset: pheno_slim synonym: "osteoid tissue" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pre-bone" EXACT [PSPUB:0000170] synonym: "prebone" EXACT [VSAO:curator] synonym: "prebone tissue" EXACT [FMA:66830, MP:0002113] xref: EMAPA:37923 {source="MA:th"} xref: FMA:66830 xref: galen:Osteoid xref: NCIT:C33228 xref: SCTID:39365008 xref: UMLS:C0682561 {source="ncithesaurus:Osteoid"} xref: VSAO:0000046 xref: Wikipedia:Osteoid xref: XAO:0004035 is_a: UBERON:0002481 {source="VSAO"} ! bone tissue property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/9/9c/Active_osteoblasts.jpg" xsd:anyURI property_value: UBPROP:0000001 "Bone tissue that is an unmineralized bone matrix deposited by osteoblasts prior to the mineralization of bone tissue.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000046", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070", source="PSPUB:0000170"} property_value: UBPROP:0000001 "Newly formed organic bone matrix secreted by osteoblasts, that exists prior to calcification; it is comprised mainly of type I collagen fibers, chondroitin sulfate and osteocalci[ISBN:0-683-40008-8]n" xsd:string {reference="ISBN:0-683-40008-8", source="MP:0010924"} property_value: UBPROP:0000012 "Note that in VSAO this was classified both as tissue and acellular extracellular matrix. Consider also the AEO class 'bone condensation'. is_a intercellular matrix in FMA." xsd:string {external_ontology="VSAO"} [Term] id: UBERON:0008886 name: pulmonary vascular system namespace: uberon def: "The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins." [ISBN:0073040584, Wikipedia:Pulmonary_circulation] subset: human_reference_atlas synonym: "pulmonary circulatory system" EXACT [FMA:45621] synonym: "pulmonary system" EXACT [ISBN:0073040584] xref: FMA:45621 xref: Wikipedia:Pulmonary_circulation is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0007798 {source="Obol"} ! vascular system relationship: has_part UBERON:0002012 ! pulmonary artery relationship: has_part UBERON:0002016 ! pulmonary vein property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Subdivision of cardiovascular system which has as its parts the pulmonary arterial and venous tree organs.[FMA]" xsd:string {ontology="FMA", source="FMA:45621"} [Term] id: UBERON:0008887 name: rectal venous plexus namespace: uberon def: "The hemorrhoidal plexus (or rectal venous plexus) surrounds the rectum, and communicates in front with the vesical venous plexus in the male, and the uterovaginal plexus in the female. A free communication between the portal and systemic venous systems is established through the hemorrhoidal plexus." [Wikipedia:Rectal_venous_plexus] synonym: "haemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus] synonym: "hemorrhoidal plexus" RELATED [Wikipedia:Rectal_venous_plexus] synonym: "plexus haemorrhoidalis" RELATED LATIN [Wikipedia:Rectal_venous_plexus] synonym: "plexus venosus rectalis" RELATED LATIN [Wikipedia:Rectal_venous_plexus] xref: FMA:18933 xref: NCIT:C32728 xref: SCTID:303051005 xref: UMLS:C0226766 {source="ncithesaurus:Hemorrhoidal_Plexus"} xref: Wikipedia:Rectal_venous_plexus is_a: UBERON:0001593 {source="FMA"} ! venous plexus intersection_of: UBERON:0001593 ! venous plexus intersection_of: surrounds UBERON:0001052 ! rectum relationship: surrounds UBERON:0001052 ! rectum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/6/69/Gray587.png" xsd:anyURI [Term] id: UBERON:0008895 name: splanchnocranium namespace: uberon def: "Subdivision of endoskeleton derived from pharyngeal arches." [https://orcid.org/0000-0002-6601-2165, ISBN:0073040584, Wikipedia:Facial_skeleton] subset: human_reference_atlas synonym: "branchial arch skeleton" RELATED [] synonym: "gill arch skeleton" RELATED [] synonym: "pharyngeal arch" RELATED INCONSISTENT [VSAO:0000149] synonym: "pharyngeal arch skeleton" RELATED [ZFA:0001216] synonym: "pharyngeal endoskeleton" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pharyngeal skeleton" RELATED [ZFA:0001216] synonym: "visceral cranium" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "visceral skeletal system" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "visceral skeleton" RELATED [UBERONREF:0000007] synonym: "viscerocranium" EXACT INCONSISTENT [VHOG:0000315, Wikipedia:Viscerocranium, ZFA:0001216] xref: AAO:0010157 xref: TAO:0001216 xref: VHOG:0000315 xref: VSAO:0000149 xref: Wikipedia:Facial_skeleton xref: XAO:0003176 xref: ZFA:0001216 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011159 ! primary subdivision of cranial skeletal system disjoint_from: UBERON:0011156 ! facial skeleton relationship: develops_from UBERON:0002539 {source="https://github.com/obophenotype/uberon/issues/83"} ! pharyngeal arch relationship: has_developmental_contribution_from UBERON:0003099 {notes="redundant", source="Grays", source="PMID:11237469"} ! cranial neural crest relationship: overlaps UBERON:0011156 {gci_relation="part_of", gci_filler="NCBITaxon:89593"} ! facial skeleton property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and consists of the jaws, hyoid and branchial arches.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001216", ontology="TAO", source="ZFIN:curator"} property_value: UBPROP:0000001 "Anatomical cluster that is part of the cranium and consists of the jaws, hyoid, and branchial arches.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010157", ontology="AAO", source="AAO:EJS"} property_value: UBPROP:0000001 "The part of the skull derived from the embryonic pharyngeal arches. [Biology_Online][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000315", ontology="VHOG", source="http://bgee.unil.ch/"} property_value: UBPROP:0000003 "The skull of ancestral tetrapods has the three basic components that we have been considering: (1) chondrocranium, (2) splanchnocranium, and (3) dermatocranium (reference 1); Each part of the skull arises from a separate phylogenetic source. The most ancient part is the splanchnocranium (visceral cranium), which first arose to support pharyngeal slits in protochordates (reference 2).[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000315", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.242, ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.235", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "many sources define this as the part of the endoskeletal that is from pharyngeal arches - this would make it part-disjoint from dermatocranium. However, there are many bones in AOs that have part-paths to both" xsd:string property_value: UBPROP:0000012 "VSAO labels this term 'pharyngeal arch' (2012-06-01) - however, it clearly means pharyngeal arch skeleton." xsd:string {external_ontology="VSAO"} [Term] id: UBERON:0008896 name: post-hyoid pharyngeal arch namespace: uberon def: "A pharyngeal arch that is posterior to the hyoid arch. i.e. any pharyngeal arch with a number 3 or higher." [https://orcid.org/0000-0002-6601-2165] subset: efo_slim synonym: "branchial arch" EXACT [ZFA:0001613] synonym: "branchial arches" EXACT PLURAL [ZFA:0001613] synonym: "branchial bar" EXACT [ZFA:0001613] synonym: "branchial bars" EXACT PLURAL [ZFA:0001613] synonym: "gill arch" EXACT [ZFA:0001613] synonym: "gill arches 1-5" EXACT [ZFA:0001613] synonym: "gill bar" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "pharyngeal arch 3-7" EXACT [ZFA:0001613] synonym: "visceral arches 3-7" EXACT [ZFA:0001613] xref: AAO:0010362 xref: BTO:0002152 xref: EFO:0003694 xref: SCTID:308766004 xref: TAO:0001597 xref: XAO:0000099 xref: ZFA:0001613 is_a: UBERON:0002539 ! pharyngeal arch intersection_of: UBERON:0002539 ! pharyngeal arch intersection_of: posterior_to UBERON:0003066 ! pharyngeal arch 2 relationship: posterior_to UBERON:0003066 ! pharyngeal arch 2 property_value: UBPROP:0000001 "Posterior-most stream of cranial neural crest, which sub-divides during migration.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010362", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0008907 name: dermal bone namespace: uberon def: "Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/267, VSAO:0000130] synonym: "dermal bones" RELATED PLURAL [ZFA:0001590] xref: AAO:0010769 xref: TAO:0001590 xref: VSAO:0000130 xref: Wikipedia:Dermal_bone xref: XAO:0004015 xref: ZFA:0001590 is_a: UBERON:0004756 {source="wd"} ! dermal skeletal element is_a: UBERON:0007842 {source="VSAO"} ! membrane bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0010364 ! dermal skeleton relationship: part_of UBERON:0010364 {source="VSAO"} ! dermal skeleton property_value: UBPROP:0000001 "Intramembranous bone that forms superficially in the organism.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001590", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000012 "other AOs are not yet in sync with this classification" xsd:string [Term] id: UBERON:0008909 name: perichordal bone namespace: uberon def: "Bone element that is adjacent to the notochord." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, VSAO:0000307] synonym: "perichordal bone" RELATED [ZFA:0001629] synonym: "perichordal bones" EXACT PLURAL [ZFA:0001629] xref: AAO:0010777 xref: TAO:0001639 xref: VSAO:0000307 xref: ZFA:0001629 is_a: UBERON:0012075 {notes="not in VSAO", source="ZFA"} ! replacement bone intersection_of: UBERON:0001474 ! bone element intersection_of: adjacent_to UBERON:0002328 ! notochord relationship: adjacent_to UBERON:0002328 ! notochord property_value: editor_note "We go with the latest VSAO in making this a subtype of bone, and add a logical definition based on the textual definition in VSAO. We also include the subtyping under 'replacement bone', for consistency with ZFA" xsd:string property_value: UBPROP:0000001 "Replacement bone that forms within the connective tissue surrounding the notochord.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001639", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0008946 name: lung parenchyma namespace: uberon def: "A parenchyma that is part of a lung." [OBOL:automatic] synonym: "parenchyma of lung" RELATED [BTO:0000763] synonym: "pulmonary parenchyma" RELATED [EMAPA:35522] synonym: "respiratory portion of lung" EXACT [FMA:27360] xref: EMAPA:35522 xref: FMA:27360 xref: MA:0003168 xref: SCTID:201712001 is_a: UBERON:0000353 {source="FMA"} ! parenchyma is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 {source="FMA"} ! lung [Term] id: UBERON:0008947 name: respiratory primordium namespace: uberon xref: EHDAA2:0004069 xref: NCIT:C34283 xref: UMLS:C1514898 {source="ncithesaurus:Respiratory_Primordium"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 {source="Obol"} ! primordium relationship: has_potential_to_develop_into UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003258 ! endoderm of foregut [Term] id: UBERON:0008962 name: forelimb bone namespace: uberon def: "A bone that is part of a forelimb region. Examples: humerus, any of the phalanges. Counter-example: scapula (a bone of the pectoral girdle). Note that we consider the forelimb to end at the shoulder." [https://orcid.org/0000-0002-6601-2165] synonym: "free forelimb bone" EXACT [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "wing bone" NARROW SENSU [Geisha:syn, NCBITaxon:8782, OBOL:automatic] xref: GAID:178 xref: MESH:D001133 xref: NCIT:C12983 xref: SCTID:368532003 xref: UMLS:C0003793 {source="ncithesaurus:Bone_of_the_Upper_Extremity"} is_a: UBERON:0002428 ! limb bone is_a: UBERON:0010741 ! bone of pectoral complex is_a: UBERON:0015021 ! forelimb endochondral element intersection_of: UBERON:0015021 ! forelimb endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0010883 ! forelimb cartilage element [Term] id: UBERON:0008969 name: dental follicle namespace: uberon def: "A sac containing the developing tooth and its odontogenic organ. The dental follicle (DF) differentiates into the periodontal ligament. In addition, it may be the precursor of other cells of the periodontium, including osteoblasts, cementoblasts and fibroblasts. They develop into the alveolar bone, the cementum with Sharpey's fibers and the periodontal ligament fibers respectively." [Wikipedia:Dental_follicle] synonym: "dental sac" RELATED [MA:0003121, Wikipedia:Dental_follicle] synonym: "tooth follicle" RELATED [BTO:0000337] xref: BTO:0000337 xref: EMAPA:35275 xref: MA:0003121 xref: NCIT:C34138 xref: SCTID:110975002 xref: Wikipedia:Dental_follicle is_a: UBERON:0007499 ! epithelial sac is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010371 ! ecto-epithelium relationship: has_part CL:0007002 ! precementoblast relationship: part_of UBERON:0008281 ! tooth bud [Term] id: UBERON:0008987 name: renal parenchyma namespace: uberon def: "The functional tissue of the kidney, consisting of the nephrons." [BTO:0003604] synonym: "kidney parenchyma" RELATED [BTO:0003604] synonym: "parenchyma of kidney" EXACT [FMA:15574] xref: BTO:0003604 xref: FMA:15574 xref: SCTID:29704000 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000353 {source="FMA"} ! parenchyma intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 {source="FMA"} ! kidney [Term] id: UBERON:0008989 name: submucosal esophageal gland namespace: uberon def: "One of the racemose glands in the walls of the esophagus that in humans are small and serve principally to lubricate the food but in some birds secrete a milky fluid on which the young are fed." [BTO:0003634, Wikipedia:Esophageal_glands] synonym: "esophageal gland" EXACT [FMA:9404] synonym: "glandulae oesophageae" EXACT [Wikipedia:Esophageal_glands] synonym: "mucous gland of submucosa of esophagus" EXACT [FMA:9404] synonym: "submocosal esophageal gland" RELATED [] xref: BTO:0003634 xref: FMA:9404 xref: NCIT:C32536 xref: SCTID:322749003 xref: UMLS:C0227178 {source="ncithesaurus:Esophageal_Gland"} xref: Wikipedia:Esophageal_glands is_a: UBERON:0003408 ! gland of digestive tract is_a: UBERON:0005178 ! thoracic cavity element is_a: UBERON:0011148 ! submucosal gland intersection_of: UBERON:0011148 ! submucosal gland intersection_of: part_of UBERON:0001043 ! esophagus relationship: located_in UBERON:0001972 ! submucosa of esophagus relationship: part_of UBERON:0001043 ! esophagus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/e8/Illu_esophageal_layers.jpg" xsd:anyURI [Term] id: UBERON:0008998 name: vasculature of brain namespace: uberon alt_id: UBERON:0005284 def: "System pertaining to blood vessels in the brain." [BTO:0003840] subset: efo_slim synonym: "brain vasculature" EXACT [] synonym: "cerebrovascular system" EXACT [BTO:0003840] synonym: "intracerebral vasculature" EXACT [FMA:61935] xref: BTO:0003840 xref: EFO:0003491 xref: EMAPA:35186 xref: FMA:242007 xref: FMA:61935 xref: SCTID:362029003 xref: TAO:0000099 xref: ZFA:0000099 is_a: UBERON:0006876 ! vasculature of organ is_a: UBERON:0036303 ! vasculature of central nervous system relationship: part_of UBERON:0000955 ! brain [Term] id: UBERON:0009010 name: periurethral tissue namespace: uberon def: "Any portion of tissue that surrounds a urethra." [UBERON:cjm] xref: BTO:0005081 xref: SCTID:256880003 is_a: UBERON:0000479 ! tissue intersection_of: UBERON:0000479 ! tissue intersection_of: surrounds UBERON:0000057 ! urethra relationship: part_of UBERON:0001556 ! lower urinary tract relationship: surrounds UBERON:0000057 ! urethra [Term] id: UBERON:0009014 name: lower back skin namespace: uberon def: "A zone of skin that is part of a lower back." [OBOL:automatic] subset: organ_slim xref: EMAPA:37281 {source="MA:th"} xref: MA:0000504 xref: SCTID:286601005 is_a: UBERON:0001068 ! skin of back is_a: UBERON:0003836 {source="MA"} ! abdominal segment skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0005462 ! lower back relationship: part_of UBERON:0005462 ! lower back [Term] id: UBERON:0009015 name: upper back skin namespace: uberon def: "A zone of skin that is part of a dorsal thoracic segment of trunk." [OBOL:automatic] xref: EMAPA:37280 {source="MA:th"} xref: MA:0000510 xref: SCTID:304890003 is_a: UBERON:0001068 ! skin of back is_a: UBERON:0001418 {source="MA"} ! skin of thorax intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0008231 ! dorsal thoracic segment of trunk relationship: part_of UBERON:0008231 ! dorsal thoracic segment of trunk [Term] id: UBERON:0009027 name: vesical artery namespace: uberon def: "An artery that supplies blood to the urinary bladder." [http://orcid.org/0000-0002-6601-2165] synonym: "arteria vesicali" EXACT LATIN [] synonym: "vesical arteries" EXACT PLURAL [] xref: EMAPA:37131 {source="MA:th"} xref: MA:0002078 xref: SCTID:244307000 is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001255 ! urinary bladder relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0001255 ! urinary bladder [Term] id: UBERON:0009029 name: pudendal vein namespace: uberon def: "Either the internal or external pudendal vein, running from the genital-vulvar area and abdomen and down the leg." [http://orcid.org/0000-0002-6601-2165, https://veintreatmentcenter.com/vein-information/pudendal-veins/] synonym: "pudic vein" RELATED [] synonym: "vena pudendae" EXACT LATIN [doi:10.1002/ca.23705] synonym: "vena pudendales" EXACT LATIN [doi:10.1002/ca.23705] xref: EMAPA:37184 {source="MA:th"} xref: MA:0002202 xref: SCTID:395225000 is_a: UBERON:0001638 {source="MA"} ! vein is_a: UBERON:0003520 ! pelvis blood vessel [Term] id: UBERON:0009030 name: left pulmonary vein namespace: uberon def: "Vein that drains left lung and returns blood to the heart." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37165 {source="MA:th"} xref: MA:0002207 xref: NCIT:C48946 xref: SCTID:304057004 xref: UMLS:C0226670 {source="ncithesaurus:Left_Pulmonary_Vein"} is_a: UBERON:0002016 ! pulmonary vein intersection_of: UBERON:0002016 ! pulmonary vein intersection_of: drains UBERON:0002168 ! left lung relationship: drains UBERON:0002168 ! left lung property_value: UBPROP:0000001 "A vein that returns oxygenated blood from the left lung to the left atrium of the heart[ncithesaurus:Left_Pulmonary_Vein]." xsd:string {source="ncithesaurus:Left_Pulmonary_Vein"} [Term] id: UBERON:0009032 name: right pulmonary vein namespace: uberon def: "Vein that drains right lung and returns blood to the heart." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37379 {source="MA:th"} xref: MA:0002208 xref: NCIT:C48947 xref: SCTID:304056008 xref: UMLS:C0226669 {source="ncithesaurus:Right_Pulmonary_Vein"} is_a: UBERON:0002016 ! pulmonary vein intersection_of: UBERON:0002016 ! pulmonary vein intersection_of: drains UBERON:0002167 ! right lung relationship: drains UBERON:0002167 ! right lung property_value: UBPROP:0000001 "A vein that returns oxygenated blood from the right lung to the left atrium of the heart[ncithesaurus:Right_Pulmonary_Vein]." xsd:string {source="ncithesaurus:Right_Pulmonary_Vein"} [Term] id: UBERON:0009097 name: gravid organism namespace: uberon def: "An organism containing a developing embryo, fetus, or unborn offspring within the body." [BTO:0004733] synonym: "gravid" RELATED [BTO:0004733] synonym: "pregnant adult" RELATED [BTO:0004733] synonym: "pregnant adult stage" RELATED [BTO:0004733] synonym: "pregnant organism" RELATED [] synonym: "pregnant stage" RELATED [BTO:0004733] xref: BTO:0004733 is_a: UBERON:0007023 ! adult organism intersection_of: UBERON:0007023 ! adult organism intersection_of: has_part UBERON:0000922 ! embryo relationship: has_part UBERON:0000922 ! embryo relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa relationship: participates_in GO:0007565 ! female pregnancy [Term] id: UBERON:0009098 name: gravid uterus namespace: uberon def: "The uterus in pregnancy." [http://medical-dictionary.thefreedictionary.com/gravid+uterus] synonym: "womb" RELATED [] xref: NCIT:C12406 xref: ncithesaurus:Gravid_Uterus xref: SCTID:362253003 xref: UMLS:C1514389 {source="ncithesaurus:Pregnant_Uterus"} is_a: UBERON:0000995 ! uterus intersection_of: UBERON:0000995 ! uterus intersection_of: location_of UBERON:0000922 ! embryo relationship: contains_process GO:0007565 ! female pregnancy relationship: location_of UBERON:0000922 ! embryo relationship: part_of UBERON:0009097 ! gravid organism [Term] id: UBERON:0009117 name: indifferent gonad namespace: uberon def: "A gonad prior to differentiating into a definitive testis or ovary." [http://www.medterms.com/script/main/art.asp?articlekey=8981] comment: typically part of the embryo - however, in male tammar wallabies the gonads are indifferent at the neonatal stage[8827321] subset: organ_slim synonym: "gonad rudiment" RELATED [] xref: EHDAA2:0000716 xref: NCIT:C34192 xref: UMLS:C1512703 {source="ncithesaurus:Indifferent_Gonad"} is_a: UBERON:0000991 ! gonad relationship: part_of UBERON:0009196 ! indifferent external genitalia [Term] id: UBERON:0009124 name: geniculate placode namespace: uberon def: "Rostralmost epibranchial placode. Associated with 1st branchial cleft." [NCBIBook:NBK53175] comment: Taxonomic equivalence to EHDAA2 class made on basis of shared development: gives rise to geniculate ganglion synonym: "epibranchial placode 1" EXACT [EHDAA2:0004206] synonym: "facial epibranchial placode" EXACT [XAO:0004211] synonym: "facial placode" EXACT [ZFA:0001295] synonym: "facial VII placode" RELATED [] synonym: "hyoid placode" RELATED [ISBN:0471888893] synonym: "hyoid VII placode" RELATED [ISBN:0471888893] xref: EHDAA2:0004206 xref: TAO:0001295 xref: XAO:0004211 xref: ZFA:0001295 is_a: UBERON:0003078 {source="ZFA"} ! epibranchial placode [Term] id: UBERON:0009125 name: petrosal placode namespace: uberon def: "Epibranchial placode between geniculate and nodose. Associated with 2nd branchial cleft." [NCBIBook:NBK53175] comment: Taxonomic equivalence to EHDAA2 class made on basis of shared development: gives rise to glossopharyngeal ganglion synonym: "epibranchial placode 2" EXACT [EHDAA2:0004207] synonym: "glossopharyngeal epibranchial placode" EXACT [XAO:0004212] synonym: "glossopharyngeal IX placode" EXACT [ISBN:0471888893] synonym: "glossopharyngeal placode" EXACT [ISBN:0471888893, ZFA:0001296] xref: EHDAA2:0004207 xref: TAO:0001296 xref: XAO:0004212 xref: ZFA:0001296 is_a: UBERON:0003078 {source="ZFA"} ! epibranchial placode [Term] id: UBERON:0009127 name: epibranchial ganglion namespace: uberon def: "Cranial ganglion which develops from an epibranchial placode." [PMID:20133851, ZFIN:curator] comment: Epibranchial ganglia orchestrate the development of the cranial neurogenic crest synonym: "epibranchial ganglia" EXACT PLURAL [ZFA:0001555] xref: TAO:0001555 xref: ZFA:0001555 is_a: UBERON:0001714 {source="ZFA"} ! cranial ganglion is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001714 ! cranial ganglion intersection_of: develops_from UBERON:0003078 ! epibranchial placode relationship: develops_from UBERON:0003078 {source="NCBIBook:NBK53175"} ! epibranchial placode [Term] id: UBERON:0009129 name: right atrium endocardium namespace: uberon def: "Endocardium that is part of the right atrium." [http://orcid.org/0000-0002-6601-2165] synonym: "endocardium of right atrium" EXACT [FMA:7281] synonym: "right atrial endocardium" EXACT [FMA:7281] synonym: "right atrium endocardial tissue" RELATED [VHOG:0001228] xref: EHDAA2:0000274 xref: FMA:7281 xref: NCIT:C102339 xref: SCTID:3194006 xref: VHOG:0001228 is_a: UBERON:0000487 ! simple squamous epithelium is_a: UBERON:0002166 ! endocardium of atrium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002078 ! right cardiac atrium relationship: develops_from UBERON:0005092 {source="EHDAA2"} ! right horn of sinus venosus relationship: part_of UBERON:0002078 ! right cardiac atrium relationship: part_of UBERON:0006218 {source="EHDAA2"} ! common atrial chamber [Term] id: UBERON:0009133 name: pleuroperitoneal membrane namespace: uberon alt_id: UBERON:0009146 def: "A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities." [http://medical-dictionary.thefreedictionary.com/pleuroperitoneal+membrane, Wikipedia:Pleuroperitoneal] synonym: "pleuroperitoneal fold" EXACT [VHOG:0000757] synonym: "pleuroperitoneal membranes" EXACT PLURAL [EHDAA2:0001483] xref: EHDAA2:0001483 xref: EMAPA:17709 xref: NCIT:C34256 xref: SCTID:361429005 xref: UMLS:C1283968 {source="ncithesaurus:Pleuroperitoneal_Membrane"} xref: VHOG:0000757 xref: Wikipedia:Pleuroperitoneal is_a: UBERON:0002050 {source="EHDAA2"} ! embryonic structure is_a: UBERON:0005291 ! embryonic tissue relationship: adjacent_to UBERON:0001179 ! peritoneal cavity relationship: adjacent_to UBERON:0002402 ! pleural cavity property_value: UBPROP:0000003 "In hagfishes a transverse septum extends upward from the ventral body wall posterior to the heart, partly separating an anterior pericardial cavity from a larger peritoneal cavity. (...) These basic relationships have not been modified by urodeles. The small pericardial cavity remains far forward where it is separated by a transverse septum from the principal coelom, which may now be called a pleuroperitoneal cavity because slender lungs are present. (...) The heart [of other tetrapods] is separated from the lungs (and liver if present) by more or less horizontal partitions that have their origin in the embryo as folds on the serous membrane of the right and left lateral body walls. These grow out to join in the midline of the body. They are called lateral mesocardia (birds) or pleuropericardial membranes. Posteriorly they join the transverse septum to form the adult pericardial membrane, or pericardium. (...) In their partitioning of their coelom, embryonic mammals resemble first early fishes (incomplete partition, posterior to heart, consisting of the transverse septum) and then reptiles (pericardium derived from transverse septum and pleuropericardial membranes). Mammals then separate paired pleural cavities from the peritoneal cavity by a diaphragm. The ventral portion of this organ comes from the transverse septum. The dorsal portion is derived from the dorsal mesentery and from still another pair of outgrowths from the lateral body wall, the pleuroperitoneal membranes.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000757", ontology="VHOG", source="ISBN:978-0471090588 Hildebrand M, Analysis of vertebrate structure (1983) p.205-206", source="http://bgee.unil.ch/"} [Term] id: UBERON:0009141 name: craniocervical region vein namespace: uberon def: "A vein that is part of a craniocervical region." [OBOL:automatic] synonym: "craniocervical vein" EXACT [] synonym: "head and neck veins" EXACT [EHDAA2:0004542] synonym: "vein of head and neck" EXACT [] xref: EHDAA2:0004542 xref: SCTID:32945007 is_a: UBERON:0013140 ! systemic vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0007811 ! craniocervical region [Term] id: UBERON:0009142 name: entire embryonic mesenchyme namespace: uberon alt_id: UBERON:0003313 def: "Sum total of mesenchyme in the embryo." [https://github.com/obophenotype/human-developmental-anatomy-ontology/issues/7] xref: EHDAA2:0001113 xref: EHDAA:177 xref: EMAPA:16097 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000477 ! anatomical cluster relationship: composed_primarily_of UBERON:0003104 ! mesenchyme relationship: has_developmental_contribution_from UBERON:0000926 {source="EHDAA2"} ! mesoderm relationship: part_of UBERON:0000922 ! embryo property_value: editor_note "consider adding new class (EMAPA:16097) for mesenchyme of embryo (some mesenchyme is extraembryonic - e.g. amnion mesoderm)" xsd:string [Term] id: UBERON:0009145 name: pharyngeal region of foregut namespace: uberon synonym: "pharyngeal region" EXACT [EMAPA:16549] xref: EMAPA:16549 xref: RETIRED_EHDAA2:0001454 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0001041 {source="EHDAA2"} ! foregut [Term] id: UBERON:0009191 name: sphenoid bone pre-cartilage condensation namespace: uberon def: "A sphenoid endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] xref: EHDAA2:0003446 xref: EMAPA:18015 is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation is_a: UBERON:0009891 ! facial mesenchyme is_a: UBERON:0014387 ! mesenchyme derived from neural crest is_a: UBERON:0015060 ! sphenoid endochondral element intersection_of: UBERON:0015060 ! sphenoid endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001703 {source="EHDAA2"} ! neurocranium relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium [Term] id: UBERON:0009192 name: basisphenoid pre-cartilage condensation namespace: uberon synonym: "basi-sphenoid pre-cartilage condensation" EXACT [EHDAA2:0003447] xref: EHDAA2:0003447 xref: EMAPA:18013 is_a: UBERON:0005866 {source="EHDAA2"} ! pre-cartilage condensation is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0007213 ! mesenchyme derived from head neural crest relationship: develops_from UBERON:0006904 {source="EHDAA2"} ! head mesenchyme from mesoderm relationship: develops_from UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest relationship: part_of UBERON:0002241 {source="EHDAA2"} ! chondrocranium [Term] id: UBERON:0009193 name: sphenoid cartilage element namespace: uberon def: "A sphenoid endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "sphenoid bone cartilage condensation" EXACT [EHDAA2:0001888] xref: EHDAA2:0001888 is_a: UBERON:0003932 ! cartilage element of chondrocranium is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation is_a: UBERON:0009891 ! facial mesenchyme is_a: UBERON:0014387 ! mesenchyme derived from neural crest is_a: UBERON:0015060 ! sphenoid endochondral element intersection_of: UBERON:0015060 ! sphenoid endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0009191 ! sphenoid bone pre-cartilage condensation [Term] id: UBERON:0009194 name: basisphenoid cartilage condenstion namespace: uberon synonym: "basisphenoid cartilage condensation" EXACT [VHOG:0001338] xref: EHDAA2:0000166 xref: EMAPA:18338 xref: VHOG:0001338 is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0007213 ! mesenchyme derived from head neural crest is_a: UBERON:0009891 ! facial mesenchyme relationship: develops_from UBERON:0009192 {source="EHDAA2"} ! basisphenoid pre-cartilage condensation relationship: part_of UBERON:0009193 {source="EHDAA2"} ! sphenoid cartilage element [Term] id: UBERON:0009196 name: indifferent external genitalia namespace: uberon subset: organ_slim xref: EHDAA2:0004021 is_a: UBERON:0004176 {source="cjm"} ! external genitalia relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:0009198 name: craniofacial suture namespace: uberon def: "Any suture between cranial and/or facial bones." [GO:0097094] synonym: "articulation of skull bones" RELATED [OBOL:automatic] synonym: "joint of the skull bones" EXACT [OBOL:automatic] is_a: UBERON:0002209 ! fibrous joint intersection_of: UBERON:0002209 ! fibrous joint intersection_of: connects UBERON:0003457 {minCardinality="2"} ! head bone relationship: connects UBERON:0003457 ! head bone relationship: part_of UBERON:0010323 ! cranial skeletal system property_value: editor_note "we follow GO in dividing sutures into cranial and facial and making a grouping class, but this is not consistent with FMA" xsd:string [Term] id: UBERON:0009199 name: facial suture namespace: uberon def: "Any suture between facial bones." [GO:0097096] is_a: UBERON:0009198 ! craniofacial suture is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0009198 ! craniofacial suture intersection_of: connects UBERON:0003462 {minCardinality="2"} ! facial bone relationship: connects UBERON:0003462 {notes="between two adjacent facial bones"} ! facial bone relationship: part_of UBERON:0011156 ! facial skeleton [Term] id: UBERON:0009200 name: limb epidermis namespace: uberon def: "The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium." [GOC:dph, GOC:sdb_2009, GOC:tb] xref: EMAPA:32728 is_a: UBERON:0001003 ! skin epidermis is_a: UBERON:3000981 ! limb external integument structure intersection_of: UBERON:0001003 ! skin epidermis intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0009201 name: nephric duct namespace: uberon def: "A nephric duct is a tube that drains a primitive kidney[GO]." [GO:0072176] comment: pronephric duct or mesonephric duct xref: EMAPA:16577 xref: Wikipedia:Wolffian_duct is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0006553 ! renal duct is_a: UBERON:0006555 ! excretory tube union_of: UBERON:0003060 ! pronephric duct union_of: UBERON:0003074 ! mesonephric duct [Term] id: UBERON:0009203 name: internasal suture namespace: uberon def: "A suture joining the nasal bones." [Wikipedia:Internasal_suture] synonym: "inter-nasal suture" EXACT [] synonym: "internasal suture of skull" EXACT [FMA:52959] synonym: "nasal suture" BROAD [GO:0097097] synonym: "sutura internasalis" EXACT [Wikipedia:Internasal_suture] synonym: "sutura internasalis" RELATED LATIN [Wikipedia:Internasal_suture] xref: FMA:52959 xref: SCTID:368990004 xref: Wikipedia:Internasal_suture is_a: UBERON:0011160 ! nasal suture intersection_of: UBERON:0009199 ! facial suture intersection_of: connects UBERON:0001681 {cardinality="2"} ! nasal bone [Term] id: UBERON:0009204 name: medial nasal process mesenchyme namespace: uberon def: "Mesenchyme that is part of a medial nasal prominence." [OBOL:automatic] xref: EHDAA2:0001077 xref: EMAPA:16810 xref: FMA:312659 is_a: UBERON:0009501 ! mesenchyme of fronto-nasal process intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004068 ! medial nasal prominence relationship: part_of UBERON:0004068 {source="EHDAA2"} ! medial nasal prominence [Term] id: UBERON:0009210 name: pharyngeal membrane namespace: uberon def: "A thin fold of ectoderm and endoderm that separates the pharyngeal pouches from the pharyngeal clefts in a developing embryo." [http://musom.marshall.edu/anatomy/grosshom/z_devbranc.html] comment: each membrane is initially composed of an inner layer formed by the endodermal lining of a branchial pouch and an outer layer formed by the ectodermal lining of the branchial groove; later, these two layers become separated by a thin layer of mesoderm; only the first branchial membrane contributes to the formation of an adult structure, i.e. the tympanic membrane (aka eardrum); the second, third, and fourth membranes are obliterated[MP] subset: pheno_slim synonym: "branchial arch membrane" EXACT [EMAPA:32749] synonym: "branchial membrane" EXACT [] synonym: "pharyngeal membrane" EXACT [] xref: EMAPA:32749 xref: FMA:295758 xref: NCIT:C34251 xref: UMLS:C1519040 {source="ncithesaurus:Pharyngeal_Membrane"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: has_part UBERON:0000924 ! ectoderm relationship: has_part UBERON:0000925 ! endoderm relationship: overlaps UBERON:0004117 ! pharyngeal pouch relationship: overlaps UBERON:0005879 ! pharyngeal cleft relationship: part_of UBERON:0002539 {source="EMAPA"} ! pharyngeal arch property_value: UBPROP:0000003 "In all vertebrates, the endodermal epithelium lining each pouch contacts the surface ectoderm of the clefts to form a series of bilayered branchial membranes, that break down in fish to form the gill openings.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001427", ontology="VHOG", source="ISBN:978-0124020603 Kaufman MH, Bard JBL, The anatomical basis of mouse development (1999) p.72", source="http://bgee.unil.ch/"} [Term] id: UBERON:0009213 name: pharyngeal membrane of 1st arch namespace: uberon def: "A pharyngeal membrane that separates the first pharyngeal cleft from the first pharyngeal pouch." [http://orcid.org/0000-0002-6601-2165] synonym: "1st branchial membrane" EXACT [EMAPA:16992] synonym: "1st pharyngeal membrane" EXACT [VHOG:0001427] synonym: "future tympanic membrane" EXACT [EMAPA:17281] synonym: "tympanic membrane primordium" EXACT [ISBN:1416037055] xref: EHDAA:3788 xref: EMAPA:16121 xref: EMAPA:16992 xref: EMAPA:17281 xref: VHOG:0001427 is_a: UBERON:0009210 ! pharyngeal membrane relationship: overlaps UBERON:0005872 ! 1st arch pharyngeal cleft relationship: overlaps UBERON:0007122 ! pharyngeal pouch 1 relationship: part_of UBERON:0004362 {source="EMAPA"} ! pharyngeal arch 1 property_value: editor_note "check EMAPA - 3 terms appear to match. We follow EMAPA in making each membrane part of the arch with the same number, though in fact it is between these arches" xsd:string [Term] id: UBERON:0009291 name: cartilaginous vertebral centrum namespace: uberon def: "Cartilaginous form of a vertebral centrum, a skeletal element that functionally replaces the notochord[VSAP,modified]." [http://orcid.org/0000-0002-6601-2165, VSAO:0000183, VSAO:curator] comment: cartilaginous centrum of vertebra[PMID:11746457] synonym: "cartilaginous centrum of vertebra" EXACT [] synonym: "postcaudal cartilaginous centrum" NARROW [PMID:11746457] xref: SCTID:317278007 is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0016491 ! vertebral centrum element intersection_of: UBERON:0016491 ! vertebral centrum element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: part_of UBERON:0011094 ! vertebra cartilage element [Term] id: UBERON:0009292 name: embryonic nasal process namespace: uberon synonym: "nasal placode" RELATED [] xref: EHDAA2:0000581 xref: EHDAA:4776 xref: EMAPA:16680 xref: FMA:293971 xref: SCTID:308881001 is_a: UBERON:0012314 ! embryonic facial prominence property_value: UBPROP:0000012 "medial or lateral; in EHDAA2 also frontonasal or intermaxillary" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0009471 name: dorsum of tongue namespace: uberon def: "The superior surface of the tongue divided by the sulcus terminalis into an anterior two-thirds, the presulcal part (pars presulcalis). and a posterior one-third, the postsulcal part (pars postsulcalis)." [http://www.drugs.com/dict/dorsum-of-tongue.html] synonym: "dorsal tongue" EXACT [FMA:54651] synonym: "dorsum linguae" EXACT [http://www.drugs.com/dict/dorsum-of-tongue.html] synonym: "tongue dorsum" EXACT [FMA:54651] xref: FMA:54651 xref: NCIT:C32482 xref: SCTID:66938003 xref: UMLS:C0226952 {source="ncithesaurus:Dorsum_of_the_Tongue"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0001723 {source="FMA"} ! tongue [Term] id: UBERON:0009472 name: axilla namespace: uberon def: "The axilla is the area directly under the joint where the forelimb connects to the shoulder." [Wikipedia:Axilla] subset: efo_slim subset: pheno_slim synonym: "arm pit" EXACT [Wikipedia:Axilla] synonym: "armpit" EXACT [Wikipedia:Axilla] synonym: "armpits" RELATED [Wikipedia:Axilla] synonym: "axilla" RELATED LATIN [Wikipedia:Axilla] synonym: "axillae" RELATED [Wikipedia:Axilla] synonym: "axillary region" EXACT [FMA:24864] synonym: "axillary region" RELATED [Wikipedia:Axilla] synonym: "oxter" RELATED [Wikipedia:Axilla] synonym: "regio axillaris" EXACT LATIN [FMA:TA] synonym: "underarm" RELATED [Wikipedia:Axilla] xref: CALOHA:TS-2208 xref: EFO:0001395 xref: FMA:24864 xref: galen:Axilla xref: MESH:D001365 xref: NCIT:C12674 xref: SCTID:362732006 xref: UMLS:C0004454 {source="ncithesaurus:Axilla"} xref: Wikipedia:Axilla is_a: UBERON:0034929 ! external soft tissue zone relationship: part_of UBERON:0001421 {source="FMA"} ! pectoral girdle region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f2/Gray411.png" xsd:anyURI property_value: UBPROP:0000007 "axillary" xsd:string [Term] id: UBERON:0009477 name: associated mesenchyme of otic placode namespace: uberon def: "Mesenchyme that is part of a otic placode." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0001340 xref: EMAPA:16196 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003069 ! otic placode relationship: develops_from UBERON:0007213 ! mesenchyme derived from head neural crest relationship: part_of UBERON:0003069 ! otic placode [Term] id: UBERON:0009479 name: ectoderm of buccopharyngeal membrane namespace: uberon def: "An ectoderm that is part of a buccopharyngeal membrane." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000190 xref: EMAPA:16260 is_a: UBERON:0000924 ! ectoderm intersection_of: UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0006211 ! buccopharyngeal membrane relationship: part_of UBERON:0006211 ! buccopharyngeal membrane [Term] id: UBERON:0009480 name: endoderm of buccopharyngeal membrane namespace: uberon def: "An endoderm that is part of a buccopharyngeal membrane." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000191 xref: EMAPA:16261 is_a: UBERON:0000925 ! endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0006211 ! buccopharyngeal membrane relationship: part_of UBERON:0006211 ! buccopharyngeal membrane [Term] id: UBERON:0009482 name: associated mesenchyme of foregut-midgut junction namespace: uberon def: "Mesenchyme that is part of a foregut-midgut junction." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000570 xref: EMAPA:16364 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006235 ! foregut-midgut junction relationship: part_of UBERON:0006235 ! foregut-midgut junction [Term] id: UBERON:0009483 name: mesentery of foregut-midgut junction namespace: uberon def: "A mesentery that is part of a foregut-midgut junction." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "foregut-midgut junction mesentery" EXACT [VHOG:0000430] xref: EHDAA2:0000575 xref: EMAPA:16365 xref: VHOG:0000430 is_a: UBERON:0002095 ! mesentery intersection_of: UBERON:0002095 ! mesentery intersection_of: part_of UBERON:0006235 ! foregut-midgut junction relationship: part_of UBERON:0006235 ! foregut-midgut junction property_value: UBPROP:0000003 "Although all vertebrates have a digestive tract and accessory glands, various parts of this system are not necessarily homologous, analogous, or even present in all species. Therefore, broad comparisons can be best made under the listings of headgut, foregut, midgut, pancreas and biliary system, hindgut.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000430", ontology="VHOG", source="ISBN:978-0521617147 Stevens CE and Hume ID, Comparative physiology of the vertebrate digestive system (2004) p.11", source="http://bgee.unil.ch/"} [Term] id: UBERON:0009494 name: pharyngeal arch mesenchymal region namespace: uberon def: "A portion of mesenchymal tissue associated with an individual pharyngeal arch." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "branchial arch mesenchyme" EXACT [MP:0011262] synonym: "pharyngeal arch mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:32755 xref: FMA:295694 is_a: UBERON:0005253 ! head mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002539 ! pharyngeal arch relationship: has_developmental_contribution_from UBERON:0003099 {source="cjm"} ! cranial neural crest relationship: part_of UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme property_value: editor_note "this represents a part of the entire arch mesenchyme (UBERON:0010046), and is therefore a superclass of the individual arch mesenchyme classes. Alternate definition: primordial embryonic connective tissue associated with the branchial arches, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to facial and cranial nerve-associated structures." xsd:string {source="MP:0011262"} [Term] id: UBERON:0009497 name: epithelium of foregut-midgut junction namespace: uberon def: "An epithelium that is part of a foregut-midgut junction." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000573 xref: EMAPA:16564 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006235 ! foregut-midgut junction relationship: develops_from UBERON:0009550 {source="EHDAA2"} ! endoderm of foregut-midgut junction relationship: part_of UBERON:0003929 {source="EHDAA2"} ! digestive tract epithelium relationship: part_of UBERON:0006235 ! foregut-midgut junction [Term] id: UBERON:0009500 name: periotic mesenchyme namespace: uberon def: "Anatomical region that surrounds the otic vesicle." [PMID:3794595, XAO:0004474, XAO:curators] subset: emapa_ehdaa2 synonym: "otocyst associated mesenchyme" EXACT [EHDAA2:0001343] synonym: "otocyst mesenchyme" EXACT [EMAPA:16670] synonym: "periotic region" RELATED [XAO:0004474] xref: EHDAA2:0001343 xref: EMAPA:16670 xref: XAO:0004474 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: surrounds UBERON:0003051 ! ear vesicle relationship: develops_from UBERON:0009477 {source="EHDAA2"} ! associated mesenchyme of otic placode relationship: part_of UBERON:0001444 {source="XAO"} ! subdivision of head relationship: surrounds UBERON:0003051 ! ear vesicle [Term] id: UBERON:0009501 name: mesenchyme of fronto-nasal process namespace: uberon def: "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head." [MP:0011266] subset: emapa_ehdaa2 subset: pheno_slim synonym: "frontonasal mesenchyme" EXACT [MP:0011266] synonym: "naso-frontal mesenchyme" EXACT [MP:0011266] xref: EHDAA2:0004109 xref: EMAPA:16683 xref: FMA:295821 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004066 ! frontonasal prominence relationship: develops_from UBERON:0007213 ! mesenchyme derived from head neural crest relationship: part_of UBERON:0004066 ! frontonasal prominence [Term] id: UBERON:0009503 name: mesenchyme of hindgut namespace: uberon def: "Mesenchyme that is part of a developing hindgut." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "hindgut associated mesenchyme" EXACT [EHDAA2:0000780] xref: EHDAA2:0000780 xref: EMAPA:16716 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001046 ! hindgut relationship: part_of UBERON:0001046 ! hindgut [Term] id: UBERON:0009505 name: mesenchyme of trachea namespace: uberon def: "Mesenchyme that is part of a developing trachea." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "trachea associated mesenchyme" EXACT [EHDAA2:0002067] xref: EHDAA2:0002067 xref: EMAPA:16854 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003126 ! trachea relationship: develops_from UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0003126 ! trachea [Term] id: UBERON:0009506 name: mesenchyme of middle ear namespace: uberon def: "Mesenchyme that is part of a developing middle ear." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "middle ear associated mesenchyme" EXACT [EHDAA2:0001182] synonym: "otic mesenchyme" BROAD [] xref: EHDAA2:0001182 xref: EMAPA:17001 is_a: UBERON:0005253 ! head mesenchyme is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001756 ! middle ear relationship: has_developmental_contribution_from UBERON:0005689 {source="EHDAA2"} ! 2nd arch mesenchyme relationship: has_developmental_contribution_from UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme relationship: part_of UBERON:0001756 ! middle ear property_value: UBPROP:0000012 "Also 1st arch maxillary mesenchyme in EHDAA2" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0009521 name: anal membrane endodermal component namespace: uberon def: "An endoderm that is part of a anal region." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0004020 xref: EMAPA:17177 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: develops_from UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0001353 ! anal region relationship: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0009522 name: lateral lingual swelling epithelium namespace: uberon def: "An epithelium that is part of a lateral lingual swelling." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000913 xref: EMAPA:17190 xref: FMA:313717 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006757 ! lateral lingual swelling relationship: part_of UBERON:0006757 ! lateral lingual swelling [Term] id: UBERON:0009523 name: mesenchyme of handplate namespace: uberon def: "Mesenchyme that is part of a handplate." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "hand plate mesenchyme" EXACT [] synonym: "handplate mesenchyme" EXACT [EHDAA2:0000731] xref: EHDAA2:0000731 xref: EMAPA:17248 xref: EMAPA:17457 is_a: UBERON:0010377 ! mesenchyme from somatopleure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0006875 ! embryonic handplate relationship: develops_from UBERON:0003413 {source="EHDAA2"} ! pectoral appendage bud mesenchyme relationship: part_of UBERON:0006875 ! embryonic handplate property_value: UBPROP:0000012 "We group two EMAPA classes here but these may need to be separated" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0009526 name: maxillary process mesenchyme namespace: uberon def: "Mesenchyme that is part of a maxillary prominence." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "mesenchyme of maxillary process" EXACT [EMAPA:17361] synonym: "mesenchyme of maxillary prominence" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0001071 xref: EMAPA:17361 xref: FMA:312691 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005868 ! maxillary prominence relationship: part_of UBERON:0005868 ! maxillary prominence [Term] id: UBERON:0009536 name: vascular element of left lung namespace: uberon def: "A vascular plexus that is part of a left lung." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000963 xref: EMAPA:17660 is_a: UBERON:0000102 ! lung vasculature is_a: UBERON:0005629 ! vascular plexus intersection_of: UBERON:0005629 ! vascular plexus intersection_of: part_of UBERON:0002168 ! left lung relationship: part_of UBERON:0002168 ! left lung [Term] id: UBERON:0009537 name: vascular element of right lung namespace: uberon def: "A vascular plexus that is part of a right lung." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0001757 xref: EMAPA:17668 is_a: UBERON:0000102 ! lung vasculature is_a: UBERON:0005629 ! vascular plexus intersection_of: UBERON:0005629 ! vascular plexus intersection_of: part_of UBERON:0002167 ! right lung relationship: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0009548 name: hepatic sinusoid of left of lobe of liver namespace: uberon def: "A hepatic sinusoid that is part of a left lobe of liver." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "left lobe hepatic sinusoids" EXACT [VHOG:0000709] xref: EHDAA2:0001001 xref: EMAPA:18309 xref: VHOG:0000709 is_a: UBERON:0001281 ! hepatic sinusoid intersection_of: UBERON:0001281 ! hepatic sinusoid intersection_of: part_of UBERON:0001115 ! left lobe of liver relationship: develops_in UBERON:0001115 ! left lobe of liver relationship: part_of UBERON:0001115 ! left lobe of liver [Term] id: UBERON:0009549 name: hepatic sinusoid of right of lobe of liver namespace: uberon def: "A hepatic sinusoid that is part of a right lobe of liver." [OBOL:automatic] subset: emapa_ehdaa2 synonym: "right lobe hepatic sinusoids" EXACT [VHOG:0000710] xref: EHDAA2:0001009 xref: EMAPA:18316 xref: VHOG:0000710 is_a: UBERON:0001281 ! hepatic sinusoid intersection_of: UBERON:0001281 ! hepatic sinusoid intersection_of: part_of UBERON:0001114 ! right lobe of liver relationship: develops_in UBERON:0001114 ! right lobe of liver relationship: part_of UBERON:0001114 ! right lobe of liver [Term] id: UBERON:0009550 name: endoderm of foregut-midgut junction namespace: uberon def: "An endoderm that is part of a foregut-midgut junction." [OBOL:automatic] subset: emapa_ehdaa2 xref: EHDAA2:0000572 xref: EMAPA:18403 is_a: UBERON:0000925 ! endoderm intersection_of: UBERON:0000925 ! endoderm intersection_of: part_of UBERON:0006235 ! foregut-midgut junction relationship: part_of UBERON:0006235 ! foregut-midgut junction [Term] id: UBERON:0009551 name: distal segment of digit namespace: uberon def: "A segment of a digit containing the distal phalanx, and overlapping the distal interphalangeal joint[CJM]. The digit tip is derived from multiple and distinct embryonic origins, and includes the distal bone with associated marrow cavity and haematopoietic cells, ventral (flexor) and dorsal (extensor) tendons, sweat glands with myoepithelial and luminal secreting cells and associated neurons for innervation, dermis with resident melanocytes and dendritic cells, mesenchyme with resident fibroblasts, skin epidermis with hair follicles, a nail organ composed of six specific parts (the root, nail bed, nail plate, eponychium (cuticle), perionychium and hyponychium)." [DOI:10.1038/nature10346] synonym: "digit tip" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "distal digit segment" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "tip of digit" EXACT [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 {source="cjm"} ! limb segment intersection_of: has_part UBERON:0004300 {source="cjm"} ! distal phalanx intersection_of: overlaps UBERON:0009768 {source="cjm"} ! distal interphalangeal joint intersection_of: part_of UBERON:0002544 {source="cjm"} ! digit relationship: has_part UBERON:0004300 ! distal phalanx relationship: overlaps UBERON:0009768 ! distal interphalangeal joint relationship: part_of UBERON:0002544 ! digit property_value: UBPROP:0000011 "Newborn and adult mice are able to regrow forelimb (finger) and hindlimb (toe) digit tips after their amputation through the distal interphalangeal joint. Regeneration of the digit tip involves the integrated regrowth of multiple tissues within 2-3 months, reaching an external morphology that is cosmetically and functionally similar to normal digits. Most importantly, regeneration of the mouse distal digit shares morphological similarities with clinical cases documenting regrowth of missing distal portions of fingers in both children and adults" xsd:string [Term] id: UBERON:0009552 name: distal segment of manual digit namespace: uberon alt_id: UBERON:0004093 def: "A segment of the manual digit containing the distal phalanx." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "finger digit tip" EXACT [DOI:10.1038/nature10346] synonym: "finger distal segment" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "finger tip" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "fingertip" EXACT [HP:0001211] synonym: "forelimb digit tip" EXACT [DOI:10.1038/nature10346] synonym: "tip of finger" EXACT [] xref: SCTID:312543003 is_a: UBERON:0005451 ! segment of manus is_a: UBERON:0009551 ! distal segment of digit intersection_of: UBERON:0009551 ! distal segment of digit intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0002389 ! manual digit [Term] id: UBERON:0009553 name: distal segment of pedal digit namespace: uberon def: "A segment of the pedal digit containing the distal phalanx. Note this class represents a digit segment and thus includes tissues in addition to bone." [http://orcid.org/0000-0002-6601-2165] synonym: "distalmost part of toe" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "hindlimb digit tip" EXACT [DOI:10.1038/nature10346] synonym: "P3 segment of pedal digit" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "tip of toe" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "toe digit tip" EXACT [DOI:10.1038/nature10346] synonym: "toe distal segment" EXACT [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0005445 ! segment of pes is_a: UBERON:0009551 ! distal segment of digit intersection_of: UBERON:0009551 ! distal segment of digit intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0001466 ! pedal digit [Term] id: UBERON:0009559 name: metacarpal/tarsal-phalangeal joint namespace: uberon def: "A skeletal joint that connects a mesopodium bone and connects a proximal phalanx." [OBOL:automatic] synonym: "fetlock" NARROW SENSU [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788, Wikipedia:Fetlock] synonym: "metacarpo-tarsophalangeal joint" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "metapodial-phalangeal joint" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "metapodium-phalanx joint" EXACT [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0003841 ! autopod joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0003656 ! mesopodium bone intersection_of: connects UBERON:0004302 ! proximal phalanx relationship: connects UBERON:0003656 ! mesopodium bone relationship: connects UBERON:0004302 ! proximal phalanx relationship: part_of UBERON:0002544 ! digit property_value: editor_note "We include these joints as being part of the digits; this is consistent with the FMA, and makes classification easier. Note that digit and metapodial regions are part-disjoint" xsd:string [Term] id: UBERON:0009564 name: distal limb integumentary appendage namespace: uberon def: "A nail, hoof or claw." [PMID:11710767] synonym: "hoof or claw" RELATED [] synonym: "hoof, claw or nail" RELATED [] synonym: "keratin plate" RELATED [] synonym: "keratin sheath" RELATED [] synonym: "unguis" RELATED [] xref: MESH:D006724 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0013703 ! integumentary projection relationship: develops_from UBERON:0011272 {source="Wikipathways:WP2062"} ! embryonic skin basal layer relationship: part_of UBERON:0001003 ! skin epidermis relationship: part_of UBERON:0009551 {source="cjm"} ! distal segment of digit [Term] id: UBERON:0009565 name: nail of manual digit namespace: uberon def: "A nail that is part of a manual digit." [OBOL:automatic] subset: pheno_slim synonym: "claw of hand" NARROW SENSU [] synonym: "claw of manus" NARROW SENSU [] synonym: "finger nail" EXACT [FMA:54327] synonym: "fingernail" EXACT [FMA:54327] synonym: "forelimb digit claw" NARROW SENSU [EMAPA:35349] synonym: "manual claw" NARROW SENSU [] synonym: "nail of finger" EXACT [FMA:54327] synonym: "nail plate of finger" RELATED [FMA:54327] xref: EMAPA:35349 xref: FMA:54327 xref: NCIT:C32609 xref: SCTID:244197001 xref: UMLS:C0222001 {source="ncithesaurus:Fingernail"} is_a: UBERON:0001705 ! nail intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0005276 {source="FMA"} ! dorsal skin of finger relationship: part_of UBERON:0009552 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! distal segment of manual digit [Term] id: UBERON:0009566 name: intestinal submucosa namespace: uberon def: "A submucosa that is part of a intestine." [OBOL:automatic] synonym: "submucosa of intestine" EXACT [FMA:15696] xref: FMA:15696 is_a: UBERON:0018257 ! submucosa of digestive tract intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001262 {source="FMA"} ! wall of intestine [Term] id: UBERON:0009567 name: nail of pedal digit namespace: uberon def: "A nail that is part of a pedal digit." [OBOL:automatic] subset: pheno_slim synonym: "claw of foot" NARROW SENSU [] synonym: "claw of pes" NARROW SENSU [] synonym: "claw of toe" NARROW SENSU [] synonym: "hindlimb claw" NARROW SENSU [EMAPA:36457] synonym: "hindlimb digit claw" NARROW SENSU [] synonym: "nail of pes" EXACT [] synonym: "nail of toe" EXACT [FMA:54328] synonym: "nail plate of toe" RELATED [FMA:54328] synonym: "pedal claw" NARROW SENSU [] synonym: "toe nail" EXACT [FMA:54328] synonym: "toenail" EXACT [FMA:54328] xref: EMAPA:36457 xref: FMA:54328 xref: NCIT:C33790 xref: SCTID:244198006 xref: UMLS:C0222007 {source="ncithesaurus:Toe_Nail"} xref: XAO:0003103 is_a: UBERON:0001705 ! nail intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0005277 {source="FMA"} ! dorsal skin of toe relationship: part_of UBERON:0009553 {source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! distal segment of pedal digit [Term] id: UBERON:0009568 name: trunk region of vertebral column namespace: uberon def: "Subdivision of vertebral column that corresponds to the trunk of the body, containing the trunk/presacral vertebrae. In organisms that have a thoracic and lumbar distinction, this corresponds to the sum of both of these regions." [UBERONREF:0000006] subset: pheno_slim synonym: "presacral region" RELATED [AAO:0000612] synonym: "thoracolumbar column" EXACT [] synonym: "thoracolumbar region" RELATED [AAO:0000612] synonym: "thoracolumbar region of vertebral column" EXACT [] synonym: "thoracolumbar vertebrae set" EXACT [FMA:72066] synonym: "thoracolumbar vertebral column" EXACT [] synonym: "trunk region" RELATED [AAO:0000612] synonym: "trunk skeleton" RELATED [] synonym: "trunk spine" RELATED [] synonym: "trunk vertebrae series" EXACT [] synonym: "trunk vertebral column" EXACT [] xref: AAO:0000612 xref: FMA:72066 xref: NCIT:C92597 xref: SCTID:281699004 is_a: UBERON:0006077 ! subdivision of vertebral column intersection_of: UBERON:0006077 ! subdivision of vertebral column intersection_of: part_of UBERON:0002100 ! trunk intersection_of: subdivision_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk relationship: subdivision_of UBERON:0002100 ! trunk property_value: UBPROP:0000001 "Region of the vertebral column between the atlas and the sacrum consisting of seven to 285 vertebrae.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000612", ontology="AAO", source="AAO:Duellman_and_Trueb_1994"} [Term] id: UBERON:0009569 name: subdivision of trunk namespace: uberon subset: non_informative synonym: "region of trunk" EXACT [FMA:25054] synonym: "trunk subdivision" EXACT [FMA:25054] xref: FMA:25054 xref: SCTID:22943007 is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0002100 ! trunk [Term] id: UBERON:0009570 name: spinal cord sulcus limitans namespace: uberon def: "A sulcus limitans of neural tube that is part of a future spinal cord." [OBOL:automatic] synonym: "spinal cord lateral wall sulcus limitans" EXACT [EHDAA2:0001265] xref: EHDAA2:0001265 xref: EMAPA:17584 xref: VHOG:0001548 is_a: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: part_of UBERON:0006241 ! future spinal cord relationship: part_of UBERON:0006241 ! future spinal cord [Term] id: UBERON:0009576 name: medulla oblongata sulcus limitans namespace: uberon def: "A sulcus limitans of neural tube that is part of a future medulla oblongata." [OBOL:automatic] xref: EHDAA2:0001100 xref: EMAPA:17561 is_a: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: part_of UBERON:0001896 ! medulla oblongata relationship: develops_from UBERON:0009578 {source="EHDAA2"} ! myelencephalon sulcus limitans relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0009577 name: metencephalon sulcus limitans namespace: uberon def: "A sulcus limitans of neural tube that is part of a future metencephalon." [OBOL:automatic] xref: EHDAA2:0001161 xref: EMAPA:17567 is_a: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: part_of UBERON:0010092 ! future metencephalon relationship: part_of UBERON:0010092 ! future metencephalon [Term] id: UBERON:0009578 name: myelencephalon sulcus limitans namespace: uberon def: "A sulcus limitans of neural tube that is part of a future myelencephalon." [OBOL:automatic] xref: EHDAA2:0001945 is_a: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: UBERON:0005478 ! sulcus limitans of neural tube intersection_of: part_of UBERON:0010096 ! future myelencephalon relationship: part_of UBERON:0010096 ! future myelencephalon [Term] id: UBERON:0009581 name: midbrain mantle layer namespace: uberon synonym: "mantle layer lateral wall mesencephalon" RELATED [VHOG:0000910] synonym: "mantle layer lateral wall midbrain" EXACT [VHOG:0000910] synonym: "midbrain lateral wall mantle layer" EXACT [] xref: EHDAA2:0001172 xref: EMAPA:16977 xref: VHOG:0000910 is_a: UBERON:0004061 ! neural tube mantle layer intersection_of: UBERON:0004061 ! neural tube mantle layer intersection_of: part_of UBERON:0009616 ! presumptive midbrain relationship: part_of UBERON:0009616 ! presumptive midbrain [Term] id: UBERON:0009583 name: spinal cord mantle layer namespace: uberon synonym: "mantle layer lateral wall spinal cord" EXACT [VHOG:0000911] synonym: "spinal cord lateral wall mantle layer" EXACT [] xref: EMAPA:17580 xref: VHOG:0000911 is_a: UBERON:0004061 ! neural tube mantle layer intersection_of: UBERON:0004061 ! neural tube mantle layer intersection_of: part_of UBERON:0006241 ! future spinal cord relationship: part_of UBERON:0006241 ! future spinal cord [Term] id: UBERON:0009584 name: 1st arch mandibular mesenchyme namespace: uberon alt_id: UBERON:0010043 def: "Mesenchyme that is part of a 1st arch mandibular component." [OBOL:automatic] synonym: "mandibular component mesenchyme" RELATED [] synonym: "mandibular mesenchyme" RELATED [] synonym: "mesenchymal region of mandibular component of first pharyngeal arch" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "mesenchyme of mandibular component" EXACT [EMAPA:16385] xref: EHDAA2:0000034 xref: EMAPA:16385 is_a: UBERON:0010042 ! 1st arch mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0007237 ! 1st arch mandibular component relationship: part_of UBERON:0007237 {source="EMAPA"} ! 1st arch mandibular component [Term] id: UBERON:0009602 name: left lung associated mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing left lung." [OBOL:automatic] synonym: "left lung mesenchyme" EXACT [EMAPA:17654] xref: EHDAA2:0000944 xref: EMAPA:16730 xref: EMAPA:17654 is_a: UBERON:0004883 ! lung mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002168 ! left lung relationship: part_of UBERON:0002168 ! left lung [Term] id: UBERON:0009603 name: right lung associated mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing right lung." [OBOL:automatic] synonym: "right lung mesenchyme" EXACT [EMAPA:17662] xref: EHDAA2:0001739 xref: EMAPA:17662 is_a: UBERON:0004883 ! lung mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002167 ! right lung relationship: part_of UBERON:0002167 ! right lung [Term] id: UBERON:0009610 name: forebrain neural plate namespace: uberon def: "A neural plate that develops_from a future forebrain." [OBOL:automatic] xref: TAO:0007018 xref: ZFA:0007018 is_a: UBERON:0003075 ! neural plate intersection_of: UBERON:0003075 {source="ZFA"} ! neural plate intersection_of: develops_from UBERON:0006240 {source="ZFA"} ! future forebrain relationship: develops_from UBERON:0006240 ! future forebrain relationship: part_of UBERON:0003056 {source="ZFA"} ! pre-chordal neural plate [Term] id: UBERON:0009611 name: midbrain neural plate namespace: uberon def: "A neural plate that develops_from a presumptive midbrain." [OBOL:automatic] xref: TAO:0007019 xref: ZFA:0007019 is_a: UBERON:0003075 ! neural plate intersection_of: UBERON:0003075 {source="ZFA"} ! neural plate intersection_of: develops_from UBERON:0009616 {source="ZFA"} ! presumptive midbrain relationship: develops_from UBERON:0009616 ! presumptive midbrain relationship: part_of UBERON:0003056 {source="ZFA"} ! pre-chordal neural plate [Term] id: UBERON:0009614 name: hindbrain neural plate namespace: uberon def: "A neural plate that develops_from a presumptive hindbrain." [OBOL:automatic] xref: TAO:0007022 xref: ZFA:0007022 is_a: UBERON:0003075 ! neural plate intersection_of: UBERON:0003075 {source="ZFA"} ! neural plate intersection_of: develops_from UBERON:0007277 {source="ZFA"} ! presumptive hindbrain relationship: develops_from UBERON:0007277 ! presumptive hindbrain relationship: part_of UBERON:0003057 {source="ZFA"} ! chordal neural plate [Term] id: UBERON:0009615 name: midbrain hindbrain boundary neural plate namespace: uberon synonym: "MHB neural plate" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "midbrain-hindbrain boundary neural plate" EXACT [ZFA:0007044] xref: TAO:0007044 xref: ZFA:0007044 is_a: UBERON:0006598 ! presumptive structure relationship: develops_from UBERON:0007281 ! presumptive midbrain hindbrain boundary relationship: immediate_transformation_of UBERON:0007281 {notes="https://github.com/obophenotype/uberon/issues/438", source="Bgee:AN"} ! presumptive midbrain hindbrain boundary relationship: part_of UBERON:0003075 {source="ZFA"} ! neural plate property_value: editor_note "TODO - developmental relationships for lines" xsd:string [Term] id: UBERON:0009616 name: presumptive midbrain namespace: uberon def: "A presumptive structure that has the potential to develop into a midbrain." [OBOL:automatic] subset: efo_slim synonym: "early midbrain" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "future midbrain" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "mesencephalon" RELATED [EHDAA2:0000615] synonym: "presumptive mesencephalon" EXACT [ZFA:0000148] xref: BAMS:MES xref: EFO:0003432 xref: EHDAA2:0000615 xref: EMAPA:16140 xref: TAO:0000148 xref: Wikipedia:Mesencephalon xref: ZFA:0000148 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001891 ! midbrain relationship: develops_from UBERON:0003080 ! anterior neural tube relationship: develops_from UBERON:0010286 {source="ZFA"} ! midbrain neural tube relationship: has_potential_to_develop_into UBERON:0001891 ! midbrain relationship: part_of UBERON:0006238 {source="ZFA"} ! future brain property_value: editor_note "TODO - unify naming conventions" xsd:string [Term] id: UBERON:0009617 name: head paraxial mesoderm namespace: uberon def: "Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles." [PMID:21610022] synonym: "cephalic paraxial mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "cephalic paraxial mesoderm" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "cranial paraxial mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "cranial paraxial mesoderm" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "head paraxial mesenchyme" EXACT [EHDAA2:0000736, https://github.com/obophenotype/uberon/issues/30] synonym: "somitomere" RELATED [] synonym: "somitomeric mesoderm" RELATED [] xref: EHDAA2:0000736 xref: EHDAA:364 xref: EMAPA:16171 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005253 ! head mesenchyme relationship: part_of UBERON:0003077 ! paraxial mesoderm relationship: part_of UBERON:0005253 {source="EHDAA2"} ! head mesenchyme property_value: UBPROP:0000011 "A major contributor to neurocranium [PMID:16313393]" xsd:string [Term] id: UBERON:0009618 name: trunk paraxial mesoderm namespace: uberon synonym: "trunk and cervical paraxial mesenchyme" EXACT [EHDAA2:0002094] synonym: "trunk paraxial mesenchyme" RELATED [https://github.com/obophenotype/uberon/issues/30] xref: EHDAA2:0002094 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005256 ! trunk mesenchyme relationship: part_of UBERON:0003077 ! paraxial mesoderm relationship: part_of UBERON:0005256 {source="EHDAA2"} ! trunk mesenchyme [Term] id: UBERON:0009621 name: tail somite namespace: uberon def: "A somite that is part of a tail." [OBOL:automatic] xref: AAO:0010383 xref: EMAPA:16860 xref: XAO:0003143 is_a: UBERON:0002329 ! somite intersection_of: UBERON:0002329 ! somite intersection_of: part_of UBERON:0002415 ! tail relationship: part_of UBERON:0002415 ! tail [Term] id: UBERON:0009624 name: lumbar nerve namespace: uberon def: "The lumbar nerves are the five spinal nerves emerging from the lumbar vertebrae. They are divided into posterior and anterior divisions." [Wikipedia:Lumbar_nerves] synonym: "lumbar spinal nerve" EXACT [FMA:5861] synonym: "nervi lumbales" RELATED LATIN [Wikipedia:Lumbar_nerves] synonym: "nervus lumbalis" EXACT LATIN [FMA:5861, FMA:TA] xref: FMA:5861 xref: NCIT:C33015 xref: neuronames:1730 xref: SCTID:361600002 xref: UMLS:C0228897 {source="ncithesaurus:Lumbar_Nerve"} xref: Wikipedia:Lumbar_nerves is_a: UBERON:0001780 ! spinal nerve intersection_of: UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0002792 ! lumbar spinal cord relationship: extends_fibers_into UBERON:0002792 ! lumbar spinal cord property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray802.png" xsd:anyURI [Term] id: UBERON:0009625 name: sacral nerve namespace: uberon def: "The five sacral nerves emerge from the sacrum. Although the vertebral components of the sacrum are fused into a single bone, the sacral vertebrae are still used to number the sacral nerves. Posteriorly, they emerge from the posterior sacral foramina, and form the posterior branches of sacral nerves. Anteriorly, they emerge from the anterior sacral foramina, and contribute to the sacral plexus (S1-S4) and coccygeal plexus." [Wikipedia:Sacral_nerves] synonym: "nervi sacrales" RELATED LATIN [Wikipedia:Sacral_nerves] synonym: "nervus sacralis" EXACT LATIN [FMA:5862, FMA:TA] synonym: "sacral spinal nerve" EXACT [FMA:5862] xref: FMA:5862 xref: NCIT:C33505 xref: neuronames:1720 xref: SCTID:361601003 xref: UMLS:C0228922 {source="ncithesaurus:Sacral_Nerve"} xref: Wikipedia:Sacral_nerves is_a: UBERON:0001780 ! spinal nerve intersection_of: UBERON:0001780 ! spinal nerve intersection_of: extends_fibers_into UBERON:0005843 ! sacral spinal cord relationship: extends_fibers_into UBERON:0005843 ! sacral spinal cord property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/d1/Gray802.png" xsd:anyURI [Term] id: UBERON:0009644 name: trachea non-cartilage connective tissue namespace: uberon subset: human_reference_atlas xref: EMAPA:35878 xref: MA:0001859 is_a: UBERON:0003571 {source="MA"} ! trachea connective tissue property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0009647 name: tympanic membrane epithelium namespace: uberon def: "One of the two epithelia which make up the tympanic membrane (along with the fibrous layer)." [https://orcid.org/0000-0002-6601-2165, PMID:11237469] synonym: "tympanic epithelium" EXACT [MA:0001224] synonym: "tympanic membrane epithelial layer" EXACT [] xref: EMAPA:19064 xref: MA:0001224 xref: NCIT:C49308 xref: SCTID:70839004 xref: UMLS:C1711401 {source="ncithesaurus:Tympanic_Epithelium"} is_a: UBERON:0010071 ! layer of tympanic membrane is_a: UBERON:0015813 ! middle ear epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002364 ! tympanic membrane disjoint_from: UBERON:0010070 ! intermediate layer of tympanic membrane [Term] id: UBERON:0009651 name: nephron tubule basement membrane namespace: uberon def: "A basement membrane that is part of a nephron tubule." [OBOL:automatic] synonym: "kidney tubule basement membrane" EXACT [MA:0001680] synonym: "renal tubular basement membrane" EXACT [] synonym: "renal tubule basement membrane" EXACT [MA:0001680] xref: EMAPA:37490 {source="MA:th"} xref: MA:0001680 xref: NCIT:C49273 xref: SCTID:245251000 xref: UMLS:C1709901 {source="ncithesaurus:Renal_Tubule_Basement_Membrane"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005769 ! basement membrane of epithelium intersection_of: UBERON:0005769 ! basement membrane of epithelium intersection_of: part_of UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0004810 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! nephron tubule epithelium [Term] id: UBERON:0009652 name: bronchus basement membrane namespace: uberon def: "A basement membrane that is part of a bronchus." [OBOL:automatic] synonym: "bronchial basement membrane" EXACT [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37809 {source="MA:th"} xref: MA:0001832 xref: NCIT:C49208 xref: UMLS:C1707051 {source="ncithesaurus:Bronchus_Basement_Membrane"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0015329 ! respiratory system basement membrane intersection_of: UBERON:0005769 ! basement membrane of epithelium intersection_of: part_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002031 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! epithelium of bronchus property_value: UBPROP:0000012 "MA classifies as type of connective tissue: https://github.com/obophenotype/mouse-anatomy-ontology/issues/108" xsd:string {external_ontology="MA"} [Term] id: UBERON:0009653 name: trachea basement membrane namespace: uberon def: "A basement membrane that is part of a trachea." [OBOL:automatic] xref: EMAPA:37552 {source="MA:th"} xref: MA:0001854 xref: NCIT:C49302 xref: UMLS:C1710455 {source="ncithesaurus:Trachea_Basement_Membrane"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0015329 ! respiratory system basement membrane intersection_of: UBERON:0005769 ! basement membrane of epithelium intersection_of: part_of UBERON:0003126 ! trachea relationship: part_of UBERON:0001901 {is_inferred="true", source="https://github.com/obophenotype/uberon/wiki/Inferring-part-of-relationships"} ! epithelium of trachea relationship: part_of UBERON:0009644 {source="MA-modified"} ! trachea non-cartilage connective tissue [Term] id: UBERON:0009655 name: auricular artery namespace: uberon def: "An artery that supplies oxygenated blood to the ear." [ncithesaurus:Auricular_Artery] xref: EMAPA:37072 {source="MA:th"} xref: MA:0001918 xref: NCIT:C52849 xref: UMLS:C1706858 {source="ncithesaurus:Auricular_Artery"} is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001691 ! external ear relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0001691 ! external ear property_value: editor_note "add child terms" xsd:string [Term] id: UBERON:0009657 name: artery of lip namespace: uberon synonym: "labial artery" BROAD [MA:0001987] xref: EMAPA:37092 {source="MA:th"} xref: MA:0001987 xref: NCIT:C52947 xref: UMLS:C1708633 {source="ncithesaurus:Labial_Artery"} is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001833 ! lip relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0001833 ! lip [Term] id: UBERON:0009661 name: midbrain nucleus namespace: uberon def: "Nucleus located in the midbrain." [ZFIN:curator] xref: SCTID:279285003 xref: TAO:0002209 xref: ZFA:0001665 is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0001891 ! midbrain [Term] id: UBERON:0009662 name: hindbrain nucleus namespace: uberon def: "Nucleus located within the hindbrain." [ZFIN:curator] xref: TAO:0002177 xref: ZFA:0001658 is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0009663 name: telencephalic nucleus namespace: uberon def: "A nucleus of brain that is part of a telencephalon." [OBOL:automatic] xref: TAO:0002178 xref: ZFA:0001660 is_a: UBERON:0002308 ! nucleus of brain intersection_of: UBERON:0002308 ! nucleus of brain intersection_of: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0001893 ! telencephalon [Term] id: UBERON:0009664 name: gut mesentery namespace: uberon synonym: "peritoneal cavity mesentary" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "peritoneal mesentary" RELATED [http://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0004566 xref: EMAPA:32911 xref: MA:0003203 is_a: UBERON:0002095 ! mesentery relationship: located_in UBERON:0001179 {source="EHDAA2"} ! peritoneal cavity property_value: seeAlso "https://github.com/obophenotype/uberon/issues/509" xsd:anyURI [Term] id: UBERON:0009668 name: ventral mesentery namespace: uberon def: "Ventral mesentery is the part of the peritoneum closest to the navel." [Wikipedia:Ventral_mesentery] xref: EHDAA2:0004569 xref: SCTID:361430000 xref: Wikipedia:Ventral_mesentery is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: part_of UBERON:0009664 {source="EHDAA2"} ! gut mesentery property_value: UBPROP:0000011 "degenerates during development except foregut portion" xsd:string [Term] id: UBERON:0009669 name: embryonic cloacal lumen namespace: uberon def: "An anatomical space that surrounded_by a embryonic cloaca." [OBOL:automatic] xref: EHDAA2:0004586 is_a: UBERON:0012463 ! cloacal lumen intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000163 ! embryonic cloaca relationship: luminal_space_of UBERON:0000163 ! embryonic cloaca relationship: part_of UBERON:0000163 ! embryonic cloaca relationship: surrounded_by UBERON:0009846 ! embryonic cloacal epithelium [Term] id: UBERON:0009670 name: rectal lumen namespace: uberon def: "An anatomical space that surrounded_by a rectum." [OBOL:automatic] synonym: "lumen of rectum" EXACT [FMA:14598] xref: EHDAA2:0004587 xref: EMAPA:18388 xref: FMA:14598 xref: SCTID:259740004 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001052 ! rectum relationship: develops_from UBERON:0009669 {source="EHDAA2"} ! embryonic cloacal lumen relationship: luminal_space_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0012465 {source="cjm"} ! lumen of terminal part of digestive tract [Term] id: UBERON:0009678 name: tooth row namespace: uberon def: "Anatomical cluster consisting of adjacent teeth constituting a row." [ZFIN:curator] synonym: "dental arcade" EXACT [FMA:59415] synonym: "row of teeth" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "tooth rows" EXACT PLURAL [ZFA:0001642] xref: FMA:59415 xref: TAO:0001667 xref: ZFA:0001642 is_a: UBERON:0003672 ! dentition is_a: UBERON:0034926 ! anatomical row intersection_of: UBERON:0034926 ! anatomical row intersection_of: has_member UBERON:0001091 ! calcareous tooth [Term] id: UBERON:0009679 name: set of lower jaw teeth namespace: uberon def: "A tooth row that is part of a skeleton of lower jaw." [OBOL:automatic] subset: pheno_slim synonym: "arcus dentalis inferior" EXACT LATIN [FMA:TA] synonym: "lower dental arcade" EXACT [FMA:55635] synonym: "lower jaw teeth" EXACT [EHDAA2:0001029] synonym: "mandibular dental arcade" RELATED [FMA:55635] synonym: "set of all lower teeth" EXACT [FMA:55635] xref: EHDAA2:0001029 xref: FMA:55635 is_a: UBERON:0009678 ! tooth row intersection_of: UBERON:0009678 ! tooth row intersection_of: part_of UBERON:0003278 ! skeleton of lower jaw relationship: part_of UBERON:0003278 ! skeleton of lower jaw [Term] id: UBERON:0009680 name: set of upper jaw teeth namespace: uberon def: "A tooth row that is part of a skeleton of upper jaw." [OBOL:automatic] subset: pheno_slim synonym: "arcus dentalis superior" EXACT LATIN [FMA:TA] synonym: "maxillary dental arcade" RELATED [FMA:55634] synonym: "set of all upper teeth" EXACT [FMA:55634] synonym: "upper dental arcade" EXACT [FMA:55634] synonym: "upper jaw teeth" EXACT [EHDAA2:0002129] xref: EHDAA2:0002129 xref: FMA:55634 is_a: UBERON:0009678 ! tooth row intersection_of: UBERON:0009678 ! tooth row intersection_of: part_of UBERON:0003277 ! skeleton of upper jaw relationship: part_of UBERON:0003277 ! skeleton of upper jaw [Term] id: UBERON:0009708 name: dorsal pancreas namespace: uberon subset: human_reference_atlas subset: organ_slim synonym: "pancreatis dorsalis" RELATED [] xref: EHDAA2:0001371 is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005177 ! trunk region element relationship: develops_from UBERON:0010375 {source="EHDAA2"} ! pancreas dorsal primordium relationship: has_developmental_contribution_from UBERON:0003923 {source="cjm"} ! dorsal pancreatic bud relationship: part_of UBERON:0001264 {source="EHDAA2"} ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0009709 name: ventral pancreas namespace: uberon subset: human_reference_atlas subset: organ_slim synonym: "pancreatis ventralis" RELATED [] xref: EHDAA2:0001393 is_a: UBERON:0002365 {source="EHDAA2"} ! exocrine gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005177 ! trunk region element relationship: develops_from UBERON:0010376 {source="EHDAA2"} ! pancreas ventral primordium relationship: has_developmental_contribution_from UBERON:0003924 {source="cjm"} ! ventral pancreatic bud relationship: part_of UBERON:0001264 {source="EHDAA2"} ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0009712 name: endocardium of right ventricle namespace: uberon def: "Any endocardium that is part of the right ventricle of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "endocardial lining of right ventricle" RELATED [EMAPA:17341] synonym: "right ventricle endocardial tissue" RELATED [VHOG:0001235] synonym: "right ventricle endocardium" EXACT [VHOG:0001235] synonym: "right ventricular endocardium" EXACT [FMA:9536] xref: EHDAA2:0002188 xref: EMAPA:17341 xref: FMA:9536 xref: NCIT:C102343 xref: SCTID:8911002 xref: VHOG:0001235 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001081 ! endocardium of ventricle intersection_of: UBERON:0001081 ! endocardium of ventricle intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: attaches_to UBERON:0006567 {source="FMA"} ! right ventricle myocardium relationship: develops_from UBERON:0004706 {source="EHDAA2"} ! bulbus cordis relationship: part_of UBERON:0002080 ! heart right ventricle property_value: UBPROP:0000001 "Endocardium of ventricle which is continuous tricuspid valve, pulmonary valve and with the tunica intima of the pulmonary trunk." xsd:string {source="FMA:9536"} [Term] id: UBERON:0009713 name: endocardium of left ventricle namespace: uberon def: "Any endocardium that is part of the left ventricle of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "endocardial lining of left ventricle" RELATED [EMAPA:17338] synonym: "left ventricle endocardial tissue" RELATED [VHOG:0001233] synonym: "left ventricle endocardium" EXACT [VHOG:0001233] synonym: "left ventricular endocardium" EXACT [FMA:9559] xref: EHDAA2:0002182 xref: EMAPA:17338 xref: FMA:9559 xref: SCTID:191004004 xref: VHOG:0001233 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001081 ! endocardium of ventricle intersection_of: UBERON:0001081 ! endocardium of ventricle intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: attaches_to UBERON:0006566 {source="FMA"} ! left ventricle myocardium relationship: part_of UBERON:0002084 ! heart left ventricle property_value: UBPROP:0000001 "Endocardium of ventricle which is continuous with mitral valve, aortic valve, atrioventricular septum and the tunica intima of the aorta." xsd:string {source="FMA:9559"} [Term] id: UBERON:0009715 name: stomodeal lumen namespace: uberon def: "An anatomical cavity that surrounded_by a stomodeum." [OBOL:automatic] synonym: "lumen of stomatodaeum" EXACT [] synonym: "lumen of stomodeum" EXACT [] synonym: "stomatodeal cavity" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000930 ! stomodeum relationship: luminal_space_of UBERON:0000930 ! stomodeum relationship: part_of UBERON:0000930 ! stomodeum [Term] id: UBERON:0009722 name: entire pharyngeal arch endoderm namespace: uberon synonym: "pharyngeal arch endoderm" RELATED [EHDAA2:0004621] xref: EHDAA2:0004621 xref: EMAPA:32754 xref: FMA:293087 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0015833 ! foregut epithelium relationship: part_of UBERON:0003929 {source="EHDAA2"} ! digestive tract epithelium relationship: part_of UBERON:0008814 ! pharyngeal arch system [Term] id: UBERON:0009749 name: limb mesenchyme namespace: uberon def: "The primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells." [MP:0011261] subset: pheno_slim synonym: "limb mesoderm" RELATED [Geisha:syn, NCBITaxon:8782] xref: EMAPA:32705 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002101 ! limb property_value: UBPROP:0000012 "EMAPA mapping from TH" xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0009751 name: cardiac mesenchyme namespace: uberon def: "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures." [MP:0011264] subset: pheno_slim synonym: "heart mesenchyme" EXACT [EMAPA:36438] xref: EHDAA2:0004162 xref: EMAPA:36438 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart property_value: editor_note "decide whether to merge with cardiac mesoderm. In EHDAA2 this lasts CS12->unbounded, includes mesenchyme of individual components as parts" xsd:string [Term] id: UBERON:0009752 name: pancreas mesenchyme namespace: uberon def: "The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas." [MP:0011265] subset: efo_slim subset: human_reference_atlas subset: pheno_slim xref: EFO:0002557 xref: EMAPA:26220 is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0009758 name: abdominal ganglion namespace: uberon def: "A ganglion that is part of a abdominal segment of trunk." [OBOL:automatic] xref: SCTID:280508003 is_a: UBERON:0007134 ! trunk ganglion intersection_of: UBERON:0000045 ! ganglion intersection_of: part_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0009767 name: proximal interphalangeal joint namespace: uberon def: "An inter-phalangeal joint that connects a proximal phalanx to either a medial or distal phalanx." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "PIJ joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "PIP joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] xref: FMA:65022 xref: NCIT:C101528 is_a: UBERON:0006658 ! interphalangeal joint intersection_of: UBERON:0006658 ! interphalangeal joint intersection_of: connects UBERON:0004302 ! proximal phalanx relationship: connects UBERON:0004301 ! middle phalanx relationship: connects UBERON:0004302 ! proximal phalanx [Term] id: UBERON:0009768 name: distal interphalangeal joint namespace: uberon def: "An inter-phalangeal joint that connects a distal phalanx to either a medial or proximal phalanx." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "DIJ joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] synonym: "DIP joint" NARROW [Wikipedia:Interphalangeal_articulations_of_the_hand] xref: FMA:65024 xref: NCIT:C101529 is_a: UBERON:0006658 ! interphalangeal joint intersection_of: UBERON:0006658 ! interphalangeal joint intersection_of: connects UBERON:0004300 ! distal phalanx relationship: connects UBERON:0004300 ! distal phalanx [Term] id: UBERON:0009773 name: renal tubule namespace: uberon def: "A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." [DOI:10.1371/journal.pone.0099864, GO:0061333, GOC:dph, GOC:mtg_kidney_jan10] subset: grouping_class subset: pheno_slim synonym: "renal tubule (generic)" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "tubule of excretory system" EXACT [https://orcid.org/0000-0002-6601-2165, OBOL:automatic] is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0006555 ! excretory tube relationship: only_in_taxon NCBITaxon:33213 ! Bilateria property_value: IAO:0000232 "this class groups vertebrate nephron tubules with analagous structures such as insect Malpighian tubules" xsd:string [Term] id: UBERON:0009778 name: pleural sac namespace: uberon def: "A serous sac that has the pleura and the pleural cavity as parts." [https://github.com/obophenotype/uberon/issues/86] subset: non_informative xref: EHDAA2:0004737 xref: FMA:9690 xref: SCTID:361996004 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005906 ! serous sac is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0005906 ! serous sac intersection_of: has_part UBERON:0000977 ! pleura intersection_of: has_part UBERON:0002402 ! pleural cavity relationship: has_part UBERON:0000977 ! pleura relationship: has_part UBERON:0002402 ! pleural cavity relationship: in_lateral_side_of UBERON:0001004 {source="FMA-abduced-lr"} ! respiratory system relationship: part_of UBERON:0001558 {source="FMA"} ! lower respiratory tract property_value: UBPROP:0000012 "despite its name the class EHDAA2:0004737 is not a true cavity, it corresponds to what we call the sac" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0009842 name: glandular acinus namespace: uberon def: "The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form." [Wikipedia:Acinus] synonym: "acini" RELATED PLURAL [Wikipedia:Acinus] synonym: "acinus" BROAD [FMA:55588] xref: FMA:55588 xref: Wikipedia:Acinus is_a: UBERON:0034922 ! cell cluster intersection_of: UBERON:0034922 ! cell cluster intersection_of: has_part CL:0000151 ! secretory cell intersection_of: has_quality PATO:0002422 ! acinar intersection_of: part_of UBERON:0002530 ! gland relationship: has_part CL:0000151 ! secretory cell relationship: has_quality PATO:0002422 ! acinar relationship: part_of UBERON:0002530 ! gland property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/99/Gray1105.png" xsd:anyURI property_value: UBPROP:0000007 "acinar" xsd:string [Term] id: UBERON:0009844 name: urogenital sinus lumen namespace: uberon def: "An anatomical space that surrounded_by a primitive urogenital sinus." [OBOL:automatic] xref: EHDAA2:0002142 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000164 ! primitive urogenital sinus relationship: develops_from UBERON:0009669 {source="EHDAA2"} ! embryonic cloacal lumen relationship: luminal_space_of UBERON:0000164 ! primitive urogenital sinus relationship: part_of UBERON:0000164 ! primitive urogenital sinus relationship: surrounded_by UBERON:0004902 ! urogenital sinus epithelium [Term] id: UBERON:0009845 name: urogenital sinus mesenchyme namespace: uberon def: "Mesenchyme that surrounds primitive urogenital sinus." [OBOL:automatic] synonym: "UGM" EXACT ABBREVIATION [PMID:18977204] xref: EMAPA:31500 is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 {source="PMID:18977204"} ! mesenchyme intersection_of: surrounds UBERON:0000164 {source="PMID:18977204"} ! primitive urogenital sinus relationship: surrounds UBERON:0000164 ! primitive urogenital sinus property_value: UBPROP:0000011 "Androgen receptor (AR) activation releases instructive signals from UGM that acts on UGS epithelium (UGE) to stimulate cell proliferation, form prostate ductal progenitors (prostatic buds), and regulate cell adhesion dynamics to permit prostatic bud outgrowth" xsd:string [Term] id: UBERON:0009846 name: embryonic cloacal epithelium namespace: uberon def: "An epithelium that is part of a embryonic cloaca." [OBOL:automatic] synonym: "cloacal epithelium" BROAD [EHDAA2:0004585] xref: EHDAA2:0004585 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0009521 ! anal membrane endodermal component is_a: UBERON:0012481 ! cloacal epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000163 ! embryonic cloaca relationship: develops_from UBERON:0003353 {source="EHDAA2"} ! epithelium of hindgut relationship: part_of UBERON:0000163 ! embryonic cloaca relationship: part_of UBERON:0003929 {source="EHDAA2"} ! digestive tract epithelium [Term] id: UBERON:0009850 name: nematode larva namespace: uberon def: "A multicellular organism that existence_starts_and_ends_during a nematode larval stage." [OBOL:automatic] is_a: UBERON:0002548 ! larva intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_and_ends_during UBERON:0004729 ! nematode larval stage relationship: existence_starts_and_ends_during UBERON:0004729 ! nematode larval stage property_value: RO:0002175 NCBITaxon:6239 [Term] id: UBERON:0009854 name: digestive tract diverticulum namespace: uberon def: "Branch or outpocketing of the digestive tract." [https://orcid.org/0000-0002-6601-2165] synonym: "diverticulum of gut" RELATED [FBbt:00100316] synonym: "intestinal pouch" RELATED [] xref: FBbt:00100316 is_a: UBERON:0004921 ! subdivision of digestive tract is_a: UBERON:0009856 ! sac intersection_of: UBERON:0009856 ! sac intersection_of: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0009856 name: sac namespace: uberon synonym: "diverticulum" RELATED [] synonym: "pouch" EXACT [] xref: galen:Diverticulum is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001987 ! saccular relationship: has_quality PATO:0001987 ! saccular [Term] id: UBERON:0009870 name: zone of stomach namespace: uberon alt_id: UBERON:0009034 def: "A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland." [ISBN:0073040584, Wikipedia:Stomach#Sections] synonym: "gastric zone" EXACT [FMA:14558] synonym: "region of stomach" EXACT [] synonym: "section of stomach" EXACT [] xref: EMAPA:35821 xref: FMA:14558 xref: MA:0002561 xref: SCTID:245415005 xref: Wikipedia:Stomach#Sections is_a: UBERON:0004921 ! subdivision of digestive tract is_a: UBERON:0034944 ! zone of organ intersection_of: UBERON:0034944 ! zone of organ intersection_of: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0000945 ! stomach property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/29/Regions_of_stomach.svg" xsd:anyURI property_value: editor_note "We follow Kardong in defining stomach regions by gland, but we also include 'body of stomach'. In future we may want to have different partitions of the stomach" xsd:string [Term] id: UBERON:0009871 name: nephrogenic zone namespace: uberon def: "Outer portion of the renal cortex. Site of formation of medullary and cortical elements." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "cortical nephrogenic niche" EXACT [PMID:29449449] synonym: "cortical nephrogenic zone" EXACT [PMID:29449449] synonym: "nephrogenic tissue" RELATED [] xref: EMAPA:27721 xref: http://www.gudmap.org/Images/Organ_Summaries/Metanephros/NZ.png xref: MA:0002996 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0001225 ! cortex of kidney property_value: UBPROP:0000008 "see http://www.ncbi.nlm.nih.gov/pubmed/12761251 for description of nephrogenic zone in dogfish." xsd:string [Term] id: UBERON:0009877 name: metapodium region namespace: uberon def: "Intermediate segment of the autopod, between the mesopodial region and and acropodial region. Examples: metacarpal region, metatarsal region." [https://orcid.org/0000-0002-6601-2165, MA:th] synonym: "cannon region" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "equine cannon region" NARROW [http://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "metacarpal or metatarsal part of limb" EXACT [] synonym: "metacarpus/metatarsus" RELATED [] synonym: "metacarpus/metatarsus region" EXACT [] synonym: "metapodial segment" EXACT [] synonym: "metapodium" RELATED [] xref: SCTID:370640001 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0002529 ! limb segment intersection_of: UBERON:0002529 ! limb segment intersection_of: has_skeleton UBERON:0010546 ! metapodial skeleton relationship: has_skeleton UBERON:0010546 ! metapodial skeleton relationship: part_of UBERON:0012140 {source="PHENOSCAPE:ni"} ! digitopodium region relationship: proximally_connected_to UBERON:0006716 ! mesopodium region property_value: editor_note "considering adding 'acropodial region'" xsd:string property_value: UBPROP:0000013 "Naming conventions for pod terms under discussion within phenoscape group" xsd:string [Term] id: UBERON:0009878 name: mesopodial skeleton namespace: uberon def: "The collection of all skeletal elements in a mesopodium. Examples: the tarsal skeleton, the carpal skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "basipodium" RELATED [VSAO:0005022, VSAO:NI] synonym: "basipodium skeleton" EXACT [VSAO:0005022, VSAO:NI] synonym: "carpal/tarsal skeleton" EXACT [] synonym: "mesopodial skeleton" EXACT [VSAO:0005022] synonym: "mesopodium" RELATED [VSAO:0005022, VSAO:NI] synonym: "mesopodium skeleton" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "skeletal parts of mesopodium" EXACT [https://orcid.org/0000-0002-6601-2165] xref: VSAO:0005022 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0006716 ! mesopodium region relationship: distally_connected_to UBERON:0010546 ! metapodial skeleton relationship: part_of UBERON:0006716 ! mesopodium region relationship: part_of UBERON:0006717 ! autopodial skeleton relationship: proximally_connected_to UBERON:0011584 ! zeugopodial skeleton relationship: skeleton_of UBERON:0006716 ! mesopodium region property_value: UBPROP:0000001 "Limb skeleton subdivision consisting of endochondral bones increasing the freedom of movement of the autopodia, and located between zeugopodia and autopodia.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0005022", ontology="VSAO", source="VSAO:NI"} property_value: UBPROP:0000002 "relationship type change: subclass skeletal subdivision (VSAO:0000042) CHANGED TO: distally_connected_to subdivision of skeleton (UBERON:0010912)[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0005022", ontology="VSAO"} [Term] id: UBERON:0009879 name: tarsal skeleton namespace: uberon def: "Subdivision of skeleton that consists of endochondral elements distal to the zeugopodial skeletal elements which constitute the proximal region of the posterior autopod skeleton[PHENOSCAPE:ad]." [https://github.com/obophenotype/uberon/issues/94, PHENOSCAPE:ad, VSAO:0005024] subset: pheno_slim synonym: "basipodium" RELATED [VSAO:0005024] synonym: "hind mesopodial skeleton" EXACT [] synonym: "hind mesopodium" EXACT [] synonym: "hind mesopodium skeleton" EXACT [] synonym: "mesopodium" RELATED [VSAO:0005024] synonym: "set of tarsal bones" EXACT [FMA:71339] synonym: "skeletal parts of hind mesopodium" EXACT [] synonym: "tarsal bones" RELATED [] synonym: "tarsal bones set" EXACT [FMA:71339] synonym: "tarsalia" EXACT [XAO:0003211] synonym: "tarsus" RELATED [XAO:0003211] xref: AAO:0000220 xref: EMAPA:19133 xref: FMA:71339 xref: GAID:1223 xref: MA:0000050 xref: SCTID:264228001 xref: SCTID:361796005 xref: VHOG:0001160 xref: VSAO:0005024 xref: Wikipedia:Tarsus_(skeleton) xref: XAO:0003211 is_a: UBERON:0009878 ! mesopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0004454 ! tarsal region relationship: distally_connected_to UBERON:0010545 ! metatarsus skeleton relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0001445 ! skeleton of pes relationship: part_of UBERON:0004454 ! tarsal region relationship: proximally_connected_to UBERON:0010720 ! hindlimb zeugopod skeleton relationship: skeleton_of UBERON:0004454 ! tarsal region property_value: UBPROP:0000001 "Segment of the leg corresponding to the tarsus. It consists of several elements that articulate with the tibia and fibula at one end and the metatarsals at the other end.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000220", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "The three main outgroup taxa of tetrapods, panderichthyids, osteolepiforms, and rhizodontids, have endoskeletal elements corresponding to the stylo- and zeugopodial elements in a tetrapod limb. In addition, there are elements that share the position and possibly the developmental derivation of the ulnare and the intermedium. From these observations, most authors have concluded that the stylo- and zeugopodial elements as well as the proximal mesopodial elements have counterparts in the fins of tetrapod ancestors, but there are no indications of wrist or ankle joints.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001160", ontology="VHOG", source="DOI:10.1002/jez.1100 Wagner GP, Chiu C, The tetrapod limb: A hypothesis on its origin. J Exp Zool (Mol Dev Evol) (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Not always associated with digits, in sarcopterygians the ulnare is present without true digits being formed, though their homologous radial elements are present" xsd:string {source="PHENOSCAPE:ad"} property_value: UBPROP:0000012 "we assume MA:tarsus belongs here, as there is a distinct class MA:ankle, with the tarsal bone being part of the former. XAO:tarsus is part of the hindlimb skeleton. FMA set-of class lacks definition but we assume this to be equivalent." xsd:string {external_ontology="MA"} [Term] id: UBERON:0009880 name: carpal skeleton namespace: uberon def: "Subdivision of skeleton that consists of the endochondral elements distal to the anterior limb/fin zeugopodial skeletal elements which constitute the proximal region of the anterior autopod skeleton[PHENOSCAPE:ad]." [https://github.com/obophenotype/uberon/issues/93, PHENOSCAPE:ad] synonym: "carpal bones" EXACT [EMAPA:25056, FMA:71335] synonym: "carpal bones set" EXACT [FMA:71335] synonym: "carpus" RELATED [MA:0000040, XAO:0003207] synonym: "fore mesopodial skeleton" EXACT [] synonym: "fore mesopodium" RELATED [AAO:0000201] synonym: "fore mesopodium skeleton" EXACT [] synonym: "ossa carpi" EXACT [] synonym: "ossa carpi" RELATED LATIN [Wikipedia:Carpus] synonym: "set of carpal bones" RELATED [FMA:71335] synonym: "skeletal parts of fore mesopodium" EXACT [] synonym: "skeleton of carpus" EXACT [] xref: AAO:0000201 xref: FMA:71335 xref: http://palaeos.com/vertebrates/glossary/images/382x366xUnciform1.jpg.pagespeed.ic.NirdxtwNVu.jpg xref: MA:0000040 xref: VHOG:0001161 xref: VSAO:0005023 xref: Wikipedia:Carpus xref: XAO:0003207 is_a: UBERON:0009878 ! mesopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0004452 ! carpal region relationship: distally_connected_to UBERON:0010544 ! metacarpus skeleton relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: part_of UBERON:0001442 ! skeleton of manus relationship: part_of UBERON:0004452 ! carpal region relationship: proximally_connected_to UBERON:0010703 ! forelimb zeugopod skeleton relationship: skeleton_of UBERON:0004452 ! carpal region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/58/Carpus.svg" xsd:anyURI property_value: UBPROP:0000001 "Segment of the forearm corresponding to the carpus. It consists of several elements that articulate with the radius and ulna at one end and the metacarpals at the other end.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000201", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000003 "The three main outgroup taxa of tetrapods, panderichthyids, osteolepiforms, and rhizodontids, have endoskeletal elements corresponding to the stylo- and zeugopodial elements in a tetrapod limb. In addition, there are elements that share the position and possibly the developmental derivation of the ulnare and the intermedium. From these observations, most authors have concluded that the stylo- and zeugopodial elements as well as the proximal mesopodial elements have counterparts in the fins of tetrapod ancestors, but there are no indications of wrist or ankle joints.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001161", ontology="VHOG", source="DOI:10.1002/jez.1100 Wagner GP, Chiu C, The tetrapod limb: A hypothesis on its origin. J Exp Zool (Mol Dev Evol) (2001)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000008 "Not always associated with digits, in sarcopterygians the ulnare is present without true digits being formed, though their homologous radial elements are present[PHENOSCAPE:ad]." xsd:string {source="Wikipedia:Carpus#Evolutionary_variations"} property_value: UBPROP:0000008 "The structure of the carpus varies widely between different groups of tetrapods, even among those that retain the full set of five digits. In primitive fossil amphibians, such as Eryops, the carpus consists of three rows of bones; a proximal row of three carpals, a second row of four bones, and a distal row of five bones. The proximal carpals are referred to as the radiale, intermediale, and ulnare, after their proximal articulations, and are homologous with the scaphoid, lunate, and triquetal bones respectively. The remaining bones are simply numbered, as the first to fourth centralia (singular: centrale), and the first to fifth distal carpals. Primitively, each of the distal bones appears to have articulated with a single metacarpal. However, the vast majority of later vertebrates, including modern amphibians, have undergone varying degrees of loss and fusion of these primitive bones, resulting in a smaller number of carpals. Almost all mammals and reptiles, for example, have lost the fifth distal carpal, and have only a single centrale - and even this is missing in humans. The pisiform bone is somewhat unusual, in that it first appears in primitive reptiles, and is never found in amphibians. Because many tetrapods have less than five digits on the forelimb, even greater degrees of fusion are common, and a huge array of different possible combinations are found. The wing of a modern bird, for example, has only two remaining carpals; the radiale (the scaphoid of mammals) and a bone formed from the fusion of four of the distal carpals. In some macropods, the scaphoid and lunar bones are fused into the scaphollunar bone" xsd:string property_value: UBPROP:0000012 "we assume MA:carpus belongs here, as there is a distinct class MA:wrist, with the carpal bone being part of the former. XAO:carpus is part of the forelimb skeleton. FMA set-of class lacks definition but we assume this to be equivalent." xsd:string {external_ontology="MA"} [Term] id: UBERON:0009881 name: anterior lateral plate mesoderm namespace: uberon subset: efo_slim synonym: "ALPM" EXACT [ZFA:0005041] xref: EFO:0003704 xref: TAO:0005041 xref: ZFA:0005041 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0003081 {source="ZFA"} ! lateral plate mesoderm [Term] id: UBERON:0009883 name: medullary ray namespace: uberon def: "A renal, cortical lobule, consisting of the ascending or descending limbs of the loop of Henle or of the collecting tubules; medullary rays are regions where parallel arrays of straight tubules travel perpendicular to the capsule and extend from the cortex to the medulla." [MP:0011347, Wikipedia:Bone_marrow_of_ovaryry_ray_(anatomy)] subset: human_reference_atlas subset: pheno_slim synonym: "Ferrein's pyramid" EXACT [MP:0011347] synonym: "kidney medullary ray" EXACT [MP:0011347] synonym: "renal medullary ray" EXACT [MP:0011347] xref: BTO:0001155 xref: EMAPA:37906 {source="MA:th"} xref: FMA:74299 xref: Wikipedia:Bone_marrow_of_ovaryry_ray_(anatomy) is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000064 {source="FMA"} ! organ part relationship: contributes_to_morphology_of UBERON:0001225 ! cortex of kidney relationship: overlaps UBERON:0001231 ! nephron tubule relationship: part_of UBERON:0001225 {source="MP"} ! cortex of kidney property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "FMA says parenchyma, MP says cortex" xsd:string {external_ontology="FMA"} property_value: UBPROP:0000013 "Their name is potentially misleading -- the 'medullary' refers to their destination, not their location. They are located only in the renal cortex, and not in the renal medulla" xsd:string [Term] id: UBERON:0009885 name: interlobar artery namespace: uberon def: "An artery that supplies a renal lobe." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Interlobar_arteries] subset: human_reference_atlas subset: pheno_slim synonym: "arteriae interlobares renis" EXACT PLURAL [FMA:TA] synonym: "arteriae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_arteries] synonym: "interlobar arteries of kidney" RELATED [FMA:71637] synonym: "interlobar artery of kidney" EXACT [FMA:71637] synonym: "kidney interlobar artery" EXACT [] synonym: "renal interlobar artery" EXACT [MP:0011355] synonym: "set of interlobar arteries of kidney" RELATED [FMA:71637] xref: EMAPA:37091 {source="MA:th"} xref: FMA:71637 xref: SCTID:62802007 xref: Wikipedia:Interlobar_arteries is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0009913 ! renal lobe relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0009913 ! renal lobe property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "FMA only has the set term" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0009887 name: interlobar vein namespace: uberon def: "The interlobar veins are veins of the renal circulation which drain the renal lobes." [Wikipedia:Interlobar_veins] subset: human_reference_atlas synonym: "interlobar vein of kidney" EXACT [FMA:71631] synonym: "interlobar veins of kidney" RELATED [FMA:71631] synonym: "set of interlobar veins of kidney" RELATED [FMA:71631] synonym: "venae interlobares renis" EXACT PLURAL [FMA:TA] synonym: "venae interlobares renis" RELATED LATIN [Wikipedia:Interlobar_veins] xref: FMA:71631 xref: Wikipedia:Interlobar_veins is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0009913 ! renal lobe relationship: connected_to UBERON:0001140 ! renal vein relationship: drains UBERON:0009913 ! renal lobe relationship: part_of RO:0002577 ! system property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "FMA only has the set term" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0009889 name: secondary heart field namespace: uberon def: "A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract)." [GO:0003139, GOC:mtg_heart, GOC:rl] synonym: "anterior heart field" EXACT [PMID:17276708] synonym: "anterior/second heart field" EXACT [Geisha:syn, NCBITaxon:8782] synonym: "second heart field" EXACT [XAO:0004186] synonym: "SHF" RELATED [XAO:0004186] xref: XAO:0004186 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007688 ! anlage relationship: anterior_to UBERON:0004140 {source="PMID:17276708"} ! primary heart field relationship: dorsal_to UBERON:0004140 {source="PMID:17276708"} ! primary heart field relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0003081 {source="GO:0003129"} ! lateral plate mesoderm property_value: UBPROP:0000001 "extra-cardiac population of mesodermal progenitors that gives rise to the right ventricle and outflow tract[PMID:17276708]." xsd:string {source="PMID:17276708"} property_value: UBPROP:0000008 "In general, the two studies in chick concluded that the contribution of the SHF was to the outflow tract, whereas the mouse work suggested that the second lineage contributed more broadly to the heart, including the outflow tract and much or all of the right ventricle [11-14]. These different conclusions may represent differences in the experimental approaches used or may represent bona fide differences in the contribution of the second lineage to the hearts of birds compared to mammals [11]. Alternatively, the secondary/anterior heart fields described in the chick may represent a subset of a broader field that makes a more substantial contribution to the heart, as the mouse studies suggested" xsd:string {source="PMID:17276708"} property_value: UBPROP:0000011 "in mouse has left ventricular identity[PMID:22855565]" xsd:string [Term] id: UBERON:0009891 name: facial mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing face." [OBOL:automatic] synonym: "face mesenchyme" EXACT [] synonym: "mesenchyme of face" EXACT [] xref: EMAPA:35337 xref: FMA:302884 is_a: UBERON:0005253 ! head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001456 ! face relationship: part_of UBERON:0001456 ! face [Term] id: UBERON:0009911 name: lobule namespace: uberon subset: upper_level synonym: "lobulus" EXACT LATIN [FMA:45737, FMA:TA] xref: FMA:45737 xref: NCIT:C12990 xref: UMLS:C0921005 {source="ncithesaurus:Lobule"} is_a: UBERON:0000063 {source="cjm"} ! organ subunit property_value: editor_note "todo - provide definition. Clearly distinguish between lobules, lobes and acinar parts of glands (see for example lobule of mammary gland)" xsd:string [Term] id: UBERON:0009912 name: anatomical lobe namespace: uberon def: "A portion of an organ, such as the liver, lung, breast, or brain." [ncithesaurus:Lobe] subset: upper_level synonym: "lobus" EXACT LATIN [FMA:45728, FMA:TA] xref: FMA:45728 xref: NCIT:C13393 xref: UMLS:C0796494 is_a: UBERON:0000063 {source="cjm"} ! organ subunit [Term] id: UBERON:0009913 name: renal lobe namespace: uberon def: "The portion of a kidney consisting of a renal medullary pyramid and the renal cortex above it[MP]. It is composed of many renal lobules[WP]." [MP:0011381, Wikipedia:Renal_lobe] subset: pheno_slim synonym: "kidney lobe" EXACT [MP:0011381] synonym: "lobi renales" RELATED LATIN [Wikipedia:Renal_lobe] synonym: "lobi renalis" EXACT PLURAL [Wikipedia:Renal_lobe] synonym: "lobus renalis" EXACT [http://www.mondofacto.com/facts/dictionary?lobus+renalis] xref: FMA:17881 xref: NCIT:C32894 xref: UMLS:C0736382 {source="ncithesaurus:Kidney_Lower_Lobe"} xref: Wikipedia:Renal_lobe is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0009912 ! anatomical lobe intersection_of: UBERON:0009912 ! anatomical lobe intersection_of: part_of UBERON:0002113 ! kidney relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/7/7e/Kidney_PioM.png" xsd:anyURI property_value: editor_note "todo - add has_part relationships." xsd:string property_value: UBPROP:0000008 "human kidneys have multilobar (multipyramidal) architecture while mice and rats have unilobar (unipyramidal) kidneys" xsd:string {source="MP"} [Term] id: UBERON:0009914 name: renal lobule namespace: uberon def: "The portion of a renal lobe consisting of nephrons grouped around a single medullary ray and draining into a single collecting duct; human kidneys have multilobular, multipapillary architecture while mice and rats have unilobular, unipapillary kidneys." [MP:0011382, Wikipedia:Cortical_lobule] comment: Alternate definition: One of the subdivisions of the kidney, consisting of a medullary ray and that portion of the convoluted port (renal corpuscles and convoluted tubules) associated with its collecting duct. -http://www.mondofacto.com/facts/dictionary?lobulus+corticalis+renalis subset: pheno_slim synonym: "cortical lobule" RELATED [MP:0011382, Wikipedia:Cortical_lobule] synonym: "cortical lobule of kidney" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "kidney lobule" EXACT [MP:0011382] synonym: "lobuli corticales renis" RELATED LATIN [Wikipedia:Cortical_lobule] synonym: "lobulus corticalis renalis" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "lobulus renalis" EXACT [] synonym: "renal cortical lobule" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "renculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "reniculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] synonym: "renunculus" RELATED [http://www.mondofacto.com/facts/dictionary?lobus+renalis] xref: FMA:17670 xref: SCTID:361330004 xref: Wikipedia:Cortical_lobule is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0009911 ! lobule intersection_of: UBERON:0009911 ! lobule intersection_of: part_of UBERON:0002113 ! kidney relationship: contributes_to_morphology_of UBERON:0002113 ! kidney relationship: has_part UBERON:0001285 ! nephron relationship: has_part UBERON:0009883 ! medullary ray relationship: part_of UBERON:0009913 {source="FMA"} ! renal lobe [Term] id: UBERON:0009916 name: wall of ureter namespace: uberon def: "An anatomical wall that is part of a ureter." [OBOL:automatic] synonym: "ureteral wall" EXACT [FMA:15888] xref: FMA:15888 xref: SCTID:279397004 is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000056 ! ureter relationship: has_part UBERON:0005742 ! adventitia relationship: has_part UBERON:0006660 ! muscular coat relationship: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0009919 name: ureter smooth muscle namespace: uberon def: "The smooth muscle tissue surrounding the epithelium of the ureter." [MP:0011426] subset: human_reference_atlas subset: pheno_slim synonym: "ureteral smooth muscle" EXACT [MP:0011426] synonym: "ureteral smooth muscle layer" EXACT [EMAPA:28844] xref: EMAPA:28811 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000056 ! ureter relationship: contributes_to_morphology_of UBERON:0000056 ! ureter relationship: part_of UBERON:0006855 ! muscular coat of ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0009920 name: optic neural crest namespace: uberon xref: EHDAA2:0001315 xref: EHDAA:1122 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest is_a: UBERON:0007530 {source="EHDAA2"} ! migrating mesenchyme population relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest [Term] id: UBERON:0009953 name: post-embryonic organism namespace: uberon def: "A multicellular organism that existence_starts_with a post-embryonic stage." [OBOL:automatic] synonym: "post-hatching organism" NARROW [https://orcid.org/0000-0002-6601-2165] synonym: "post-natal organism" NARROW [https://orcid.org/0000-0002-6601-2165] synonym: "postnatal mouse" NARROW [MA:0002405] synonym: "postnatal organism" EXACT [] synonym: "TS28 mouse" NARROW [MA:0002405] xref: MA:0002405 is_a: UBERON:0000468 ! multicellular organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: existence_starts_with UBERON:0000092 ! post-embryonic stage relationship: existence_starts_with UBERON:0000092 ! post-embryonic stage property_value: seeAlso "https://github.com/obophenotype/uberon/issues/667" xsd:anyURI [Term] id: UBERON:0009955 name: neurogenic placode namespace: uberon def: "Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia." [http://orcid.org/0000-0002-6601-2165, PMID:11523831] subset: efo_slim synonym: "neurogenic placodes" EXACT PLURAL [ZFA:0001309] synonym: "placodae neurogenicae" RELATED LATIN [Wikipedia:Neurogenic_placodes] xref: EFO:0003460 xref: TAO:0001309 xref: Wikipedia:Neurogenic_placodes xref: XAO:0004620 xref: ZFA:0001309 is_a: UBERON:0002546 {source="cjm"} ! cranial placode intersection_of: UBERON:0005085 ! ectodermal placode intersection_of: has_potential_to_developmentally_contribute_to CL:0000540 ! neuron intersection_of: has_potential_to_developmentally_contribute_to UBERON:0001714 ! cranial ganglion intersection_of: has_potential_to_developmentally_contribute_to UBERON:0001785 ! cranial nerve disjoint_from: UBERON:0011814 ! non-neurogenic ectodermal placode relationship: develops_from UBERON:2007013 ! preplacodal ectoderm relationship: has_potential_to_developmentally_contribute_to CL:0000540 ! neuron relationship: has_potential_to_developmentally_contribute_to UBERON:0001714 ! cranial ganglion relationship: has_potential_to_developmentally_contribute_to UBERON:0001785 ! cranial nerve property_value: IAO:0000232 "Includes: trigeminal, otic, lateral line and epibranchial placodes." xsd:string property_value: UBPROP:0000008 "While some sensory placodes (otic and olfactory) may have homologues in basal chordates (Wada et al., 1998), the so-called neurogenenic placodes (trigeminal, otic, lateral line and epibranchial placodes) appear to have emerged at a later time (Shimeld and Holland, 2000)" xsd:string {source="NCBIBook:NBK53171"} [Term] id: UBERON:0009958 name: bladder lumen namespace: uberon def: "An anatomical space that is enclosed by a urinary bladder." [OBOL:automatic] synonym: "bladder cavity" EXACT [FMA:15924] synonym: "cavity of urinary bladder" EXACT [FMA:15924] synonym: "lumen of urinary bladder" EXACT [FMA:15924] synonym: "urinary bladder lumen" EXACT [FMA:15924] xref: EHDAA2:0004058 xref: FMA:15924 xref: galen:UrinaryBladderCavity xref: SCTID:279405003 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 {source="FMA"} ! anatomical space intersection_of: luminal_space_of UBERON:0001255 {source="FMA"} ! urinary bladder relationship: develops_from UBERON:0009844 {source="EHDAA2"} ! urogenital sinus lumen relationship: luminal_space_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 {source="FMA"} ! urinary bladder [Term] id: UBERON:0009970 name: epithelium of pancreatic duct namespace: uberon def: "An epithelium that is part of a pancreatic duct." [OBOL:automatic] subset: efo_slim synonym: "pancreatic duct epithelium" EXACT [FMA:67681] synonym: "pancreatic ductal epithelium" EXACT [FMA:67681] xref: EFO:0002556 xref: FMA:67681 is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0013697 ! exocrine pancreas epithelium is_a: UBERON:0034969 ! epithelial layer of duct intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0007329 ! pancreatic duct relationship: part_of UBERON:0007329 ! pancreatic duct property_value: editor_note "in EHDAA2, the embryonic pancreatic ducts (dorsal, ventral) are classified as eithelial sacs, which would render them subclasses of this" xsd:string [Term] id: UBERON:0009972 name: ureteropelvic junction namespace: uberon def: "The junction between the ureter and the renal pelvis of the kidney." [MP:0011487] subset: pheno_slim synonym: "pelviureteric junction" EXACT [FMA:15898] synonym: "pelvoureteric junction" EXACT [] xref: EMAPA:37782 {source="MA:th"} xref: FMA:15898 xref: MA:0003021 xref: NCIT:C106203 xref: SCTID:264130006 is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000056 ! ureter intersection_of: connects UBERON:0001224 ! renal pelvis relationship: connects UBERON:0000056 ! ureter relationship: connects UBERON:0001224 ! renal pelvis relationship: contributes_to_morphology_of UBERON:0001008 ! renal system relationship: part_of UBERON:0001008 {source="MP"} ! renal system [Term] id: UBERON:0009973 name: ureterovesical junction namespace: uberon def: "The valve-like structure found at the site of entry of the ureter into the urinary bladder, normally displays an oblique angulation through the detrusor to avoid reflux of urine up the ureters and the kidney." [MP:0011488] subset: pheno_slim synonym: "vesico-ureteral junction" EXACT [MA:0003020] synonym: "vesico-ureteric junction" EXACT [] synonym: "vesicoureteric junction" EXACT [] xref: EMAPA:37783 {source="MA:th"} xref: FMA:15899 xref: MA:0003020 xref: NCIT:C106202 xref: SCTID:261187001 is_a: UBERON:0003978 ! valve is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000056 ! ureter intersection_of: connects UBERON:0001255 ! urinary bladder relationship: connects UBERON:0000056 ! ureter relationship: connects UBERON:0001255 ! urinary bladder relationship: contributes_to_morphology_of UBERON:0001008 ! renal system relationship: part_of UBERON:0001008 {source="MP"} ! renal system [Term] id: UBERON:0009979 name: condyle namespace: uberon def: "An articular prominence of a bone, typically present in pairs, resembling a pair of knuckles. Examples: Condyle of humerus, condyle of femur." [http://www.merriam-webster.com/dictionary/condyle, PHENOSCAPE:ad] synonym: "condylus" EXACT LATIN [Wikipedia:Condyle_(anatomy)] xref: FMA:75434 xref: galen:Condyle xref: NCIT:C83002 xref: SCTID:91737009 xref: TAO:0002259 xref: UMLS:C0524414 {source="ncithesaurus:Condyle"} xref: Wikipedia:Condyle_(anatomy) is_a: UBERON:0005913 {source="FMA"} ! zone of bone organ property_value: UBPROP:0000001 "Protuberance on a bone that participates in a joint with another bone.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002259", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000001 "the round prominence at the end of a bone, most often part of a joint - an articulation with another bone[WP][Wikipedia:Condyle_(anatomy)]." xsd:string {source="Wikipedia:Condyle_(anatomy)"} property_value: UBPROP:0000007 "condylar" xsd:string property_value: UBPROP:0000007 "condyloid" xsd:string [Term] id: UBERON:0009980 name: condyle of femur namespace: uberon def: "A condyle that is part of a distal epiphysis of femur." [OBOL:automatic] synonym: "condylus femoralis" EXACT [] synonym: "condylus femoris" EXACT [] synonym: "femoral condyle" EXACT [] synonym: "fibular condyle" RELATED [AAO:0000900] xref: AAO:0000900 xref: FMA:32855 xref: galen:FemoralCondyle xref: NCIT:C114186 xref: SCTID:304912006 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0009979 ! condyle intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0004406 ! distal epiphysis of femur relationship: part_of UBERON:0004406 ! distal epiphysis of femur property_value: UBPROP:0000001 "Convex articular facet of the distal head of the femur that articulates with the proximal head of the fibula.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000900", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0009984 name: medial condyle of femur namespace: uberon def: "The medial condyle is one of the two projections on the lower extremity of femur. The medial condyle is larger than the lateral (outer) condyle due to more weight bearing caused by the center of gravity being medial to the knee. On the posterior surface of the condyle the linea aspera (a ridge running down the posterior shaft of the femur) turns into the medial supracondylar ridge. The outermost protrusion on the medial surface of the medial condyle is referred to as the 'medial epicondyle' and can be palpated by running fingers medially from the patella with the knee in flexion." [Wikipedia:Medial_condyle_of_femur] subset: human_reference_atlas synonym: "c. medialis femoris" RELATED LATIN [Wikipedia:Medial_condyle_of_femur] synonym: "condylus medialis femoris" EXACT LATIN [FMA:32858, FMA:TA] synonym: "medial condyle of the femur" RELATED [Wikipedia:Medial_condyle_of_femur] synonym: "medial femoral condyle" RELATED [FMA:32858] xref: FMA:32858 xref: SCTID:182056007 xref: Wikipedia:Medial_condyle_of_femur is_a: UBERON:0009980 ! condyle of femur disjoint_from: UBERON:0009985 {source="lexical"} ! lateral condyle of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/53/Gray246.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0009985 name: lateral condyle of femur namespace: uberon def: "The lateral condyle is one of the two projections on the lower extremity of femur. It is the more prominent and is the broader both in its antero-posterior and transverse diameters." [Wikipedia:Lateral_condyle_of_femur] subset: human_reference_atlas synonym: "c. lateralis femoris" RELATED LATIN [Wikipedia:Lateral_condyle_of_femur] synonym: "condylus lateralis femoris" EXACT LATIN [FMA:32859, FMA:TA] synonym: "lateral condyle of the femur" RELATED [Wikipedia:Lateral_condyle_of_femur] synonym: "lateral femoral condyle" RELATED [FMA:32859] xref: FMA:32859 xref: SCTID:182057003 xref: Wikipedia:Lateral_condyle_of_femur is_a: UBERON:0009980 ! condyle of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/53/Gray246.png" xsd:anyURI property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0009988 name: condyle of humerus namespace: uberon def: "The distal end of the humerus, including the trochlea, capitulum and the olecranon, coronoid and radial fossae." [http://www.medilexicon.com/medicaldictionary.php?t=19715] synonym: "condylus humeri" EXACT LATIN [] synonym: "humeral condyle" EXACT [FMA:23377] xref: FMA:23377 xref: SCTID:361778001 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0009979 ! condyle intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0004404 ! distal epiphysis of humerus relationship: part_of UBERON:0004404 ! distal epiphysis of humerus property_value: RO:0002171 UBERON:0016497 property_value: UBPROP:0000008 "As in the N.A., the Condylus humeri is the whole distal end of the bone except the epicondyles. The Capitulum humeri is present in Carnivora, more distinctly in the cat than in the dog. The Fossa coronoidea, present in the cat is medial to the Fossa radialis and accommodates the Processus coronoideus medialis ulnae when the elbow is flexed. A Foramen supratrochleare occurs in carnivora and occasionally in pig.[NOMINA ANATOMICA VETERINARIA (2005)]" xsd:string [Term] id: UBERON:0009989 name: condyle of tibia namespace: uberon def: "One of the lateral or medial condyles of the tibia." [Wikipedia:Tibial_condyle] synonym: "tibial condyle" EXACT [AAO:0000899] xref: AAO:0000899 xref: SCTID:182062002 xref: Wikipedia:Tibial_condyle is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0009979 ! condyle intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0008772 ! proximal epiphysis of tibia relationship: part_of UBERON:0008772 ! proximal epiphysis of tibia property_value: UBPROP:0000001 "Convex articular facet of the distal head of the femur that articulates with the proximal head of the tibia.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000899", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0010000 name: multicellular anatomical structure namespace: uberon def: "An anatomical structure that has more than one cell as a part." [CARO:0010000] subset: common_anatomy subset: upper_level synonym: "multicellular structure" EXACT [FBbt:00100313] xref: CARO:0010000 xref: FBbt:00100313 is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_quality PATO:0001993 ! multicellular relationship: has_part CL:0000000 ! cell relationship: has_quality PATO:0001993 ! multicellular property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0010005 name: placental labyrinth villous namespace: uberon def: "The vascularized and branched structures arising from the rodent trophoblast-derived epithelium that allow an increase its surface area for the efficient exchange of nutrients and wastes between the maternal and fetal circulation." [MP:0011522] subset: pheno_slim synonym: "placental labyrinth villi" RELATED PLURAL [] synonym: "villous of placental labyrinth" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure relationship: contributes_to_morphology_of UBERON:0003946 ! placenta labyrinth relationship: part_of UBERON:0003946 {source="MP"} ! placenta labyrinth [Term] id: UBERON:0010009 name: aggregate regional part of brain namespace: uberon def: "A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]." [NLXANAT:20090509] subset: non_informative synonym: "set of nuclei of neuraxis" RELATED [FMA:256381] xref: FMA:256381 xref: NLXANAT:20090509 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034923 ! disconnected anatomical group intersection_of: UBERON:0034923 ! disconnected anatomical group intersection_of: has_member UBERON:0002616 ! regional part of brain intersection_of: part_of UBERON:0000955 ! brain relationship: has_member UBERON:0002616 ! regional part of brain relationship: part_of UBERON:0000955 ! brain property_value: editor_note "May be obsoleted." xsd:string [Term] id: UBERON:0010020 name: tubotympanic recess epithelium namespace: uberon def: "The dorsal portion of the embryonic first endodermal pharyngeal pouch; it develops into the middle ear cavity." [ISBN:0124020607, VHOG:0001297] synonym: "tubotympanic recess" RELATED [VHOG:0001297] xref: EHDAA2:0004115 xref: EHDAA:6772 xref: EMAPA:17002 xref: MA:0001218 xref: NCIT:C34318 xref: SCTID:361516008 xref: UMLS:C1284046 {source="ncithesaurus:Tubotympanic_Recess"} xref: VHOG:0001297 is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac is_a: UBERON:0015813 ! middle ear epithelium relationship: develops_from UBERON:0007122 {source="EHDAA2", source="ISBN:0073040584", source="PMID:11237469"} ! pharyngeal pouch 1 property_value: UBPROP:0000003 "The tympanic cavity and auditory tube of an amniote develop from the first embryonic pharyngeal pouch, so they are homologous to the first gill pouch, or spiracle, of a fish. We are uncertain whether this homology strictly applies to the middle ear cavity and auditory tube of lissamphibians, which show certain peculiarities in their development.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001297", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.417", source="http://bgee.unil.ch/"} [Term] id: UBERON:0010031 name: 6th arch mesenchyme namespace: uberon def: "Mesenchyme that is part of a pharyngeal arch 6." [OBOL:automatic] synonym: "6th branchial arch mesenchyme" RELATED [] synonym: "6th pharyngeal arch mesenchyme" EXACT [] synonym: "pharyngeal arch 6 mesenchyme" RELATED [] xref: EHDAA2:0004076 xref: EMAPA:32765 xref: FMA:318209 is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003117 ! pharyngeal arch 6 relationship: part_of UBERON:0003117 ! pharyngeal arch 6 [Term] id: UBERON:0010032 name: anterior part of tongue namespace: uberon def: "The portion of the tongue in front of the terminal sulcus. At the apex, thin and narrow, it is directed forward against the lingual surfaces of the lower incisor teeth. It is derived primarily from the first pharyngeal arch." [Wikipedia:Anterior_tongue] synonym: "anterior 2/3 of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "anterior 2/3 of tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "anterior two thirds of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "apex linguae" RELATED [Wikipedia:Anterior_tongue] synonym: "apex of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "buccal part of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "front of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "oral part of the tongue" RELATED [Wikipedia:Anterior_tongue] synonym: "pars anterior dorsi linguae" RELATED LATIN [Wikipedia:Anterior_tongue] xref: EMAPA:37437 {source="MA:th"} xref: FMA:229084 xref: NCIT:C32130 xref: UMLS:C0226946 {source="ncithesaurus:Apex_of_the_Tongue"} xref: Wikipedia:Anterior_tongue is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000064 ! organ part intersection_of: UBERON:0000064 {source="ISBN:1607950324"} ! organ part intersection_of: develops_from UBERON:0006260 {source="ISBN:1607950324"} ! lingual swellings intersection_of: part_of UBERON:0001723 {source="ISBN:1607950324"} ! tongue relationship: develops_from UBERON:0006260 ! lingual swellings relationship: part_of UBERON:0001723 ! tongue property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/4c/Illu04_tongue.jpg" xsd:anyURI property_value: UBPROP:0000011 "The lateral lingual swellings grow and fuse with eachother, encompassing the tuberculum impar to provide the ectodermally derived mucosa of the anterior 2/3 of the tongue" xsd:string property_value: UBPROP:0000012 "check NCIT" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0010039 name: food storage organ namespace: uberon def: "An organ of the digestive tract that is capable of retaining and storing food." [https://orcid.org/0000-0002-6601-2165] subset: functional_classification subset: grouping_class xref: BSA:0000123 xref: TADS:0000172 xref: TGMA:0001041 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013765 ! digestive system element relationship: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system property_value: IAO:0000232 "This is a very broad functionally defined grouping class that collects disparate structures from insects to vertebrates" xsd:string [Term] id: UBERON:0010042 name: 1st arch mesenchyme namespace: uberon def: "Mesenchyme that is part of a pharyngeal arch 1." [OBOL:automatic] synonym: "mesenchyme of 1st arch" EXACT [EMAPA:16128] xref: EMAPA:16128 is_a: UBERON:0009494 ! pharyngeal arch mesenchymal region intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004362 ! pharyngeal arch 1 relationship: part_of UBERON:0004362 ! pharyngeal arch 1 [Term] id: UBERON:0010045 name: 1st arch maxillary mesenchyme namespace: uberon def: "Mesenchyme that is part of a 1st arch maxillary component." [OBOL:automatic] synonym: "maxillary component mesenchyme" RELATED [] synonym: "maxillary mesenchyme" RELATED [] synonym: "mesenchyme of maxillary component" EXACT [EMAPA:16391] xref: EHDAA2:0000041 xref: EMAPA:16391 is_a: UBERON:0010042 ! 1st arch mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0007238 ! 1st arch maxillary component relationship: part_of UBERON:0007238 ! 1st arch maxillary component [Term] id: UBERON:0010046 name: entire pharyngeal arch associated mesenchyme namespace: uberon def: "The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells." [https://orcid.org/0000-0002-6601-2165, XAO:0004524] synonym: "associated mesenchyme of pharyngeal region" EXACT [EMAPA:16550] synonym: "entire branchial arch associated mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pharyngeal arch associated mesenchyme" EXACT [EHDAA2:0001459] xref: EHDAA2:0001459 xref: EMAPA:16550 xref: XAO:0004524 is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: has_developmental_contribution_from UBERON:0003099 {source="cjm"} ! cranial neural crest relationship: part_of UBERON:0008814 {source="EHDAA2"} ! pharyngeal arch system [Term] id: UBERON:0010047 name: oral gland namespace: uberon alt_id: UBERON:0003293 def: "Gland of the epithelium lining the oral cavity. The most common are the salivary glands." [ISBN:0073040584] synonym: "buccal gland" NARROW [] synonym: "gland of oral opening" RELATED [] synonym: "gland of oral region" RELATED [] synonym: "mouth gland" RELATED [] synonym: "oral cavity gland" RELATED [] synonym: "oral region gland" RELATED [] xref: EHDAA2:0001327 xref: EHDAA:2181 xref: EMAPA:16572 xref: EMAPA:16723 xref: VHOG:0000652 is_a: UBERON:0002365 ! exocrine gland is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000165 ! mouth relationship: part_of UBERON:0000165 ! mouth property_value: UBPROP:0000012 "Note that Kardong classifies lacrimal glands here. EHDAA2 includes pituitary primordium, as this develops from oral mucosa" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0010052 name: mucosa of dorsum of tongue namespace: uberon def: "A mucosa that is part of a dorsum of tongue." [OBOL:automatic] synonym: "mucosa of dorsal surface of tongue" EXACT [] xref: FMA:74871 xref: SCTID:245835003 is_a: UBERON:0005020 ! mucosa of tongue intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0009471 ! dorsum of tongue relationship: part_of UBERON:0009471 ! dorsum of tongue property_value: editor_note "check surface terms" xsd:string property_value: UBPROP:0000011 "develops fungiform papillae by WNT induction at 11 weeks pc in human. Filiform papillae develop later. ISBN:1607950324" xsd:string [Term] id: UBERON:0010056 name: future tongue namespace: uberon def: "A compound organ that has the potential to develop into a tongue." [OBOL:automatic] xref: EHDAA2:0000696 xref: EHDAA:2951 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003103 {source="EHDAA2"} ! compound organ is_a: UBERON:0005423 ! developing anatomical structure is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0003103 ! compound organ intersection_of: has_potential_to_develop_into UBERON:0001723 ! tongue relationship: has_potential_to_develop_into UBERON:0001723 ! tongue relationship: part_of UBERON:0000165 ! mouth [Term] id: UBERON:0010059 name: hypoglossal cord namespace: uberon xref: EHDAA2:0004610 is_a: UBERON:0002036 {source="EHDAA2"} ! striated muscle tissue relationship: part_of UBERON:0010056 {source="EHDAA2"} ! future tongue [Term] id: UBERON:0010063 name: tympanic cavity epithelium namespace: uberon xref: EHDAA2:0004116 is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0007499 {source="EHDAA2"} ! epithelial sac is_a: UBERON:0015813 ! middle ear epithelium relationship: develops_from UBERON:0010020 ! tubotympanic recess epithelium relationship: develops_from_part_of UBERON:0010020 {source="EHDAA2"} ! tubotympanic recess epithelium relationship: located_in UBERON:0004114 ! tympanic cavity [Term] id: UBERON:0010064 name: open anatomical space namespace: uberon def: "An anatomical space with at least one opening to another space or the exterior." [AEO:0000221] xref: AEO:0000221 xref: EHDAA2:0004616 is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: has_quality PATO:0000610 ! open relationship: connected_to UBERON:0000464 {source="cjm"} ! anatomical space relationship: has_quality PATO:0000610 ! open relationship: part_of RO:0002577 ! system [Term] id: UBERON:0010065 name: auditory meatus epithelium namespace: uberon xref: EHDAA2:0004114 is_a: UBERON:0003914 {source="EHDAA2"} ! epithelial tube is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0015814 ! outer ear epithelium relationship: develops_from UBERON:0005872 {source="EHDAA2", source="PMID:16313389"} ! 1st arch pharyngeal cleft [Term] id: UBERON:0010069 name: outer epithelial layer of tympanic membrane namespace: uberon def: "A portion of the external acoustic meatus epithelium which makes up the outer (cuticular) layer of the tympanic membrane." [https://orcid.org/0000-0002-6601-2165, PMID:11237469] synonym: "cuticular layer of tympanic membrane" EXACT [FMA:56819] synonym: "cuticular stratum of tympanic membrane" EXACT [FMA:56819] synonym: "outer cuticular layer of tympanic membrane" EXACT [FMA:56819] synonym: "outer layer of tympanic membrane" EXACT [] synonym: "tympanic membrane external acoustic meatus epithelial component" EXACT [https://orcid.org/0000-0002-6601-2165] xref: FMA:56819 xref: SCTID:39725007 is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0009647 ! tympanic membrane epithelium is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0015814 ! outer ear epithelium intersection_of: UBERON:0009647 ! tympanic membrane epithelium intersection_of: part_of UBERON:0001352 ! external acoustic meatus relationship: part_of UBERON:0001352 ! external acoustic meatus [Term] id: UBERON:0010070 name: intermediate layer of tympanic membrane namespace: uberon def: "The intermediate fibrous layer of the tympanic membrane." [https://sourceforge.net/tracker/?func=detail&aid=3468783&group_id=76834&atid=1205376, PMID:11237469] synonym: "connective tissue layer of tympanic membrane" EXACT [FMA:56830] synonym: "fibrous layer of tympanic membrane" EXACT [FMA:56830] synonym: "fibrous stratum of tympanic membrane" EXACT [FMA:56830] synonym: "intermediate fibrous layer of tympanic membrane" EXACT [FMA:56830] synonym: "tympanic endothelium" EXACT [MA:0001223] xref: EMAPA:19063 xref: FMA:56830 xref: MA:0001223 xref: SCTID:44692008 is_a: UBERON:0010071 {source="FMA"} ! layer of tympanic membrane property_value: UBPROP:0000012 "check MA" xsd:string {external_ontology="MA"} [Term] id: UBERON:0010071 name: layer of tympanic membrane namespace: uberon subset: grouping_class synonym: "tympanic membrane layer" EXACT [FMA:56732] xref: FMA:56732 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000064 ! organ part relationship: part_of UBERON:0002364 ! tympanic membrane property_value: UBPROP:0000008 "In mammals, this class groups together the two epithelial layers plus the intermediate fibrous layer" xsd:string [Term] id: UBERON:0010075 name: sacral neural crest namespace: uberon def: "One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. The vagal and sacral neural crest cells develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia." [http://www.ncbi.nlm.nih.gov/books/NBK10065/, XB:curator] xref: XAO:0004192 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0002342 ! neural crest [Term] id: UBERON:0010077 name: cuboidal epithelium namespace: uberon def: "An epithelium consisting of cuboidal epithelial cells." [Wikipedia:Cuboidal_epithelium] xref: NCIT:C32415 xref: UMLS:C0682577 {source="ncithesaurus:Cuboidal_Epithelium"} xref: Wikipedia:Cuboidal_epithelium is_a: UBERON:0000483 ! epithelium property_value: editor_note "TODO - coordinate with CL, add cuboidal cell" xsd:string property_value: UBPROP:0000012 "in NCIT this is glandular" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0010081 name: future common hepatic duct namespace: uberon def: "An extrahepatic bile duct that has the potential to develop into a common hepatic duct." [OBOL:automatic] xref: EHDAA2:0000595 is_a: UBERON:0003703 ! extrahepatic bile duct is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0034932 ! epithelium of biliary system intersection_of: UBERON:0003703 ! extrahepatic bile duct intersection_of: has_potential_to_develop_into UBERON:0001175 ! common hepatic duct relationship: develops_from UBERON:0005604 ! extrahepatic part of hepatic duct relationship: has_potential_to_develop_into UBERON:0001175 ! common hepatic duct [Term] id: UBERON:0010083 name: future dermis namespace: uberon def: "Mesenchyme that has the potential to develop into a dermis." [OBOL:automatic] xref: EHDAA2:0000598 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: has_potential_to_develop_into UBERON:0002067 ! dermis relationship: develops_from UBERON:0003089 {source="EHDAA2"} ! sclerotome relationship: develops_from UBERON:0004016 {source="XAO"} ! dermatome relationship: has_potential_to_develop_into UBERON:0002067 ! dermis relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument property_value: editor_note "check development" xsd:string [Term] id: UBERON:0010084 name: future diaphragm namespace: uberon def: "A structure that will develop into a diaphragm." [http://orcid.org/0000-0002-6601-2165] xref: EHDAA2:0000599 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001103 ! diaphragm relationship: developmentally_induced_by UBERON:0009133 {source="PMID:23586979"} ! pleuroperitoneal membrane relationship: develops_from UBERON:0005594 {source="PMID:23586979"} ! head somite relationship: has_potential_to_develop_into UBERON:0001103 ! diaphragm relationship: located_in UBERON:0002323 {source="EHDAA2"} ! coelemic cavity lumen [Term] id: UBERON:0010091 name: future hindbrain meninx namespace: uberon def: "A multi-tissue structure that has the potential to develop into a meninx of hindbrain." [OBOL:automatic] synonym: "future hindbrain meninges" EXACT [EHDAA2:0000610] xref: EHDAA2:0000610 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 ! dense mesenchyme tissue is_a: UBERON:0007645 ! future meninx intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0003291 ! meninx of hindbrain relationship: has_potential_to_develop_into UBERON:0003291 ! meninx of hindbrain relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0010092 name: future metencephalon namespace: uberon def: "A developing anatomical structure that has the potential to develop into a metencephalon." [OBOL:automatic] xref: EHDAA2:0000623 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001895 ! metencephalon relationship: has_potential_to_develop_into UBERON:0001895 ! metencephalon relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0010096 name: future myelencephalon namespace: uberon def: "A developing anatomical structure that has the potential to develop into a myelencephalon." [OBOL:automatic] xref: EHDAA2:0000640 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0005290 ! myelencephalon relationship: has_potential_to_develop_into UBERON:0005290 ! myelencephalon relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0010123 name: future facial nucleus namespace: uberon def: "A gray matter that has the potential to develop into a facial nucleus." [OBOL:automatic] xref: EHDAA2:0004639 is_a: UBERON:0002020 ! gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: has_potential_to_develop_into UBERON:0000127 ! facial nucleus relationship: has_potential_to_develop_into UBERON:0000127 ! facial nucleus [Term] id: UBERON:0010125 name: future superior salivatory nucleus namespace: uberon def: "A gray matter that has the potential to develop into a superior salivatory nucleus." [OBOL:automatic] xref: EHDAA2:0004644 is_a: UBERON:0002020 ! gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: has_potential_to_develop_into UBERON:0002149 ! superior salivatory nucleus relationship: has_potential_to_develop_into UBERON:0002149 ! superior salivatory nucleus [Term] id: UBERON:0010129 name: femur cartilage element namespace: uberon def: "A femur endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "femoral cartilage condensation" EXACT [EMAPA:17742] xref: EMAPA:17742 is_a: UBERON:0005254 ! upper leg mesenchyme is_a: UBERON:0005863 ! cartilaginous condensation is_a: UBERON:0010885 ! hindlimb cartilage element is_a: UBERON:0015052 ! femur endochondral element intersection_of: UBERON:0015052 ! femur endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006234 ! femur pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0000981 ! femur relationship: part_of UBERON:0005254 {source="EMAPA"} ! upper leg mesenchyme property_value: editor_note "TODO - request EHDAA2" xsd:string [Term] id: UBERON:0010130 name: embryonic autopod plate namespace: uberon def: "The distal elements of the developing limb of vertebrates that will give rise to the autopod (e.g. manus, pes, paw)." [https://github.com/obophenotype/mammalian-phenotype-ontology/issues/1151, MP:0004576, UBERON:cjm] synonym: "autopod plate" EXACT [] synonym: "limb plate" EXACT [] is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0002050 ! embryonic structure intersection_of: has_potential_to_develop_into UBERON:0002470 ! autopod region relationship: develops_from UBERON:0004347 ! limb bud relationship: has_potential_to_develop_into UBERON:0002470 ! autopod region [Term] id: UBERON:0010131 name: conducting tissue of heart namespace: uberon def: "Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers." [http://orcid.org/0000-0002-6601-2165] synonym: "specialized conducting tissue of heart" EXACT [FMA:83378] synonym: "specialized muscle tissue of heart" EXACT [FMA:83378] xref: EHDAA2:0004528 xref: FMA:83378 is_a: UBERON:0001133 ! cardiac muscle tissue [Term] id: UBERON:0010133 name: neuroendocrine gland namespace: uberon def: "Any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli." [ISBN:0-683-40008-8, MP:0000631] subset: pheno_slim synonym: "neuroendocrine system gland" EXACT [] xref: MA:0000720 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002368 ! endocrine gland intersection_of: UBERON:0002368 ! endocrine gland intersection_of: part_of UBERON:0001016 ! nervous system relationship: has_part CL:0000165 ! neuroendocrine cell relationship: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0010136 name: epithelial sheet namespace: uberon def: "An epithelial sheet is a flat surface consisting of closely packed epithelial cells." [GO:0002011] is_a: UBERON:0000483 ! epithelium [Term] id: UBERON:0010141 name: primitive sex cord of indifferent gonad namespace: uberon def: "A sex cord that is part of a indifferent gonad." [OBOL:automatic] synonym: "indifferent sex cord" EXACT [] synonym: "primitive sex cords" EXACT [EHDAA2:0004051] xref: EHDAA2:0004051 is_a: UBERON:0004909 ! epithelium of gonad is_a: UBERON:0005295 ! sex cord intersection_of: UBERON:0005295 {source="EHDAA2"} ! sex cord intersection_of: part_of UBERON:0009117 {source="EHDAA2"} ! indifferent gonad relationship: develops_from UBERON:0005891 {source="EHDAA2"} ! coelomic epithelium relationship: part_of UBERON:0009117 ! indifferent gonad property_value: IAO:0000232 "note that this represents the indifferent structure." xsd:string [Term] id: UBERON:0010143 name: seminal vesicle fluid namespace: uberon def: "A bodily secretion that is produced by a seminal vesicle." [http://orcid.org/0000-0002-6601-2165] synonym: "secretion of seminal vesicle" EXACT [FMA:62969] synonym: "seminal fluid" RELATED INCONSISTENT [] synonym: "seminal vesicle secretion" EXACT [FMA:62969] synonym: "vesicular fluid" BROAD [] xref: BTO:0002053 xref: FMA:62969 xref: MA:0002526 xref: NCIT:C33529 xref: NCIT:C52552 xref: UMLS:C0036614 {source="ncithesaurus:Seminal_Fluid"} xref: UMLS:C0227987 {source="ncithesaurus:Seminal_Vesicle_Secretion"} is_a: UBERON:0006530 {source="FMA"} ! seminal fluid intersection_of: UBERON:0000456 ! secretion of exocrine gland intersection_of: produced_by UBERON:0000998 ! seminal vesicle relationship: produced_by UBERON:0000998 ! seminal vesicle property_value: UBPROP:0000008 "constitutes 60-70 % of the ejaculate in humans[MP]" xsd:string property_value: UBPROP:0000009 "important for semen coagulation, sperm motility, and stability of sperm chromatin and suppression of the immune activity in the female reproductive tract[MP]" xsd:string property_value: UBPROP:0000012 "in ncit, seminal fluid is a subtype of seminal vesicle secretion" xsd:string {external_ontology="ncit"} [Term] id: UBERON:0010152 name: skin mucus namespace: uberon def: "A mucous secretion that is produced by glands in the epidermis." [http://orcid.org/0000-0002-6601-2165] synonym: "epidermal mucus" RELATED [BTO:0005082] synonym: "skin mucous" RELATED [] is_a: UBERON:0000912 ! mucus intersection_of: UBERON:0000912 ! mucus intersection_of: produced_by UBERON:0004790 ! skin mucous gland relationship: produced_by UBERON:0004790 ! skin mucous gland [Term] id: UBERON:0010156 name: sphenofrontal suture namespace: uberon def: "The Sphenofrontal suture is the cranial suture between the sphenoid bone and the frontal bone." [Wikipedia:Sphenofrontal_suture] synonym: "frontosphenoid suture" EXACT [FMA:52938] synonym: "spheno-frontal suture" RELATED [] synonym: "sphenofrontal" RELATED [Wikipedia:Sphenofrontal_suture] synonym: "sphenofrontal suture of skull" EXACT [FMA:52938] synonym: "sutura sphenofrontalis" RELATED LATIN [Wikipedia:Sphenofrontal_suture] xref: FMA:52938 xref: SCTID:136349005 xref: Wikipedia:Sphenofrontal_suture is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0000209 ! tetrapod frontal bone intersection_of: connects UBERON:0001677 ! sphenoid bone relationship: connects UBERON:0000209 ! tetrapod frontal bone relationship: connects UBERON:0001677 ! sphenoid bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/2/2d/Gray164.png" xsd:anyURI [Term] id: UBERON:0010161 name: lumen of blood vessel namespace: uberon def: "An anatomical cavity that surrounded_by a blood vessel." [OBOL:automatic] synonym: "blood vessel lumen" EXACT [] xref: FMA:312610 xref: SCTID:91747007 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001981 ! blood vessel relationship: luminal_space_of UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001981 ! blood vessel [Term] id: UBERON:0010162 name: post-anal tail tip namespace: uberon def: "The distal end of the tail." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "end of tail" RELATED [MA:0002848] synonym: "tail tip" EXACT [MA:0002848] xref: EMAPA:37760 {source="MA:th"} xref: MA:0002848 xref: XAO:0004057 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: UBERON:0011676 ! subdivision of organism along main body axis intersection_of: distalmost_part_of UBERON:0007812 ! post-anal tail relationship: distalmost_part_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0007812 {source="MA"} ! post-anal tail [Term] id: UBERON:0010183 name: liver trabecula namespace: uberon def: "A trabecula that is part of a liver." [GO:0060344, OBOL:automatic] synonym: "hepatic trabecula" RELATED [] synonym: "liver trabeculae" EXACT PLURAL [] is_a: UBERON:0000440 ! trabecula is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000440 ! trabecula intersection_of: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 ! liver [Term] id: UBERON:0010186 name: male urethral gland namespace: uberon def: "Any of the numerous small mucous-secreting glands located in the wall of the penile urethra." [MGI:anna, MP:0011794] subset: pheno_slim synonym: "gland of Littre" EXACT [] synonym: "gland of male urethra" EXACT [] synonym: "glandulae urethrales urethrae masculinae" RELATED LATIN [Wikipedia:Urethral_gland] synonym: "Littre's gland" EXACT [FMA:21443] synonym: "male urethra gland" EXACT [] synonym: "urethral gland (male)" EXACT [FMA:21443] xref: EMAPA:29645 xref: FMA:21443 xref: NCIT:C49311 xref: SCTID:303562001 xref: UMLS:C1314737 {source="ncithesaurus:Urethral_Gland"} xref: Wikipedia:Urethral_gland is_a: UBERON:0001338 ! urethral gland intersection_of: UBERON:0001338 ! urethral gland intersection_of: part_of UBERON:0001333 ! male urethra relationship: part_of UBERON:0001333 ! male urethra [Term] id: UBERON:0010187 name: female urethral gland namespace: uberon def: "An urethral gland that is part of a female urethra." [OBOL:automatic] synonym: "female urethra gland" EXACT [] synonym: "gland of female urethra" EXACT [] synonym: "urethral gland (female)" EXACT [FMA:21444] xref: EMAPA:29653 xref: FMA:21444 xref: SCTID:279476001 is_a: UBERON:0001338 ! urethral gland intersection_of: UBERON:0001338 ! urethral gland intersection_of: part_of UBERON:0001334 ! female urethra relationship: part_of UBERON:0001334 ! female urethra [Term] id: UBERON:0010188 name: protuberance namespace: uberon def: "A roughly circular bulge in a surface." [EHDAA2:0003250] xref: AEO:0000205 xref: EHDAA2:0003250 xref: FMA:82506 is_a: UBERON:0034944 {source="FMA"} ! zone of organ property_value: editor_note "requires review" xsd:string [Term] id: UBERON:0010189 name: right atrium venous valve namespace: uberon synonym: "right venous valve" RELATED [EHDAA2:0001762] xref: EHDAA2:0001762 xref: EMAPA:17010 xref: EMAPA:17328 xref: MA:0001872 is_a: UBERON:0005208 ! right atrium valve is_a: UBERON:0006675 ! venous valve intersection_of: UBERON:0006675 ! venous valve intersection_of: part_of UBERON:0002078 ! right cardiac atrium property_value: UBPROP:0000012 "part_of in EHDAA2. Only child in MA." xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0010190 name: pair of dorsal aortae namespace: uberon def: "The paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation." [ISBN:0-914294-08-3, MP:0004787] subset: pheno_slim synonym: "paired dorsal aortae" EXACT [EHDAA2:0000410] xref: EHDAA2:0000410 xref: EMAPA:18606 xref: MA:0000476 is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: has_part UBERON:0005805 ! dorsal aorta relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0010191 {source="EHDAA2"} ! aortic system [Term] id: UBERON:0010191 name: aortic system namespace: uberon xref: EHDAA2:0004512 is_a: UBERON:0011216 ! organ system subdivision relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0004571 {source="Wikipedia"} ! systemic arterial system [Term] id: UBERON:0010192 name: genital artery namespace: uberon def: "One of the laterally paired arteries that supply the gonads." [ISBN:0073040584, Wikipedia:Gonadal_artery] synonym: "gonadal artery" EXACT [] xref: Wikipedia:Gonadal_artery is_a: UBERON:0012254 ! abdominal aorta artery intersection_of: UBERON:0004573 ! systemic artery intersection_of: supplies UBERON:0000991 ! gonad relationship: supplies UBERON:0000991 ! gonad [Term] id: UBERON:0010194 name: hepatic portal system namespace: uberon def: "A portal system that begins in capillaries in the wall of the digestive tract and and runs as the hepatic portal vein to the liver." [ISBN:0073040584] synonym: "hepatic-portal system" EXACT [AAO:0010225] synonym: "portal system of liver" EXACT [] xref: AAO:0010225 is_a: UBERON:0005806 ! portal system relationship: connects UBERON:0001555 ! digestive tract relationship: connects UBERON:0002107 ! liver property_value: UBPROP:0000001 "Part of the circulatory system which includes the ventral abdominal vein, pelvic veins, and portal vein and collects blood from the pelvic region, liver, gall bladder and stomach.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010225", ontology="AAO", source="AAO:BJB"} [Term] id: UBERON:0010199 name: bona-fide anatomical boundary namespace: uberon def: "An anatomical boundary that corresponds to some physical discontinuity." [CARO:0001004] comment: One might argue that all boundaries are actually fiat in the sense that there must be some fiat element at a fine enough scale of granularity. This ontology choses to ignore this issue as below the level of granularity relevant to anatomy. (DOS121102) subset: upper_level xref: CARO:0001004 is_a: UBERON:0000466 {source="CARO"} ! immaterial anatomical entity [Term] id: UBERON:0010204 name: tail vasculature namespace: uberon def: "A vasculature that is part of a post-anal tail." [OBOL:automatic] synonym: "post-vent vasculature" EXACT [ZFA:0005037] synonym: "tail vasculature" RELATED [ZFA:0005037] xref: TAO:0005037 xref: XAO:0004151 xref: ZFA:0005037 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0007812 ! post-anal tail property_value: UBPROP:0000012 "isa blood vessel in XAO" xsd:string {external_ontology="XAO"} [Term] id: UBERON:0010212 name: laryngeal apparatus namespace: uberon def: "Apparatus located between the lungs and the buccal cavity. This apparatus is composed of a pair of arytenoid cartilages that are supported by the cricoid ring." [AAO:0000267] synonym: "laryngeal cartilage system" EXACT [EHDAA2:0000904] xref: AAO:0000267 xref: EHDAA2:0000904 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0034921 ! multi organ part structure relationship: composed_primarily_of UBERON:0001739 ! laryngeal cartilage relationship: part_of UBERON:0001737 {source="EHDAA2"} ! larynx relationship: part_of UBERON:0008895 ! splanchnocranium property_value: editor_note "check this. See also https://github.com/obophenotype/uberon/wiki/The-axial-skeleton" xsd:string [Term] id: UBERON:0010213 name: laryngeal pre-cartilage condensation namespace: uberon is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005866 ! pre-cartilage condensation relationship: develops_from UBERON:0010221 {source="EHDAA2-abstracted"} ! laryngeal associated mesenchyme relationship: part_of UBERON:0010212 {source="EHDAA2-abstracted"} ! laryngeal apparatus [Term] id: UBERON:0010221 name: laryngeal associated mesenchyme namespace: uberon comment: Many sources say: thyroid cartilage from arch 4 other laryngeal cartilage (cricoid/arytenoid) from 6? xref: EHDAA2:0004085 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue relationship: develops_from UBERON:0002539 {source="Wikipedia"} ! pharyngeal arch relationship: has_developmental_contribution_from UBERON:0003115 {source="Wikipedia"} ! pharyngeal arch 4 relationship: has_developmental_contribution_from UBERON:0003117 {source="Wikipedia"} ! pharyngeal arch 6 relationship: part_of UBERON:0001737 {source="EHDAA2"} ! larynx relationship: part_of UBERON:0008895 ! splanchnocranium [Term] id: UBERON:0010227 name: future cardiac atrium namespace: uberon def: "Multi-tissue structure that is part of the heart tube and will become the cardiac atrium." [ZFA:0001718] synonym: "presumptive atrium heart tube" EXACT [ZFA:0001718] synonym: "primordial atrium" EXACT [FMA:71005] synonym: "primordial cardiac atrium" EXACT [FMA:71005] xref: FMA:71005 xref: TAO:0002228 xref: ZFA:0001718 is_a: UBERON:0006598 ! presumptive structure relationship: has_potential_to_develop_into UBERON:0002081 ! cardiac atrium relationship: part_of UBERON:0004141 {source="ZFA"} ! heart tube [Term] id: UBERON:0010230 name: eyeball of camera-type eye namespace: uberon def: "The core globe-shaped component of the camera-type eye." [UBERON:cjm] subset: pheno_slim synonym: "bulbus oculi" EXACT [] synonym: "eye" RELATED INCONSISTENT [] synonym: "eye globe" EXACT [VHOG:0001616] synonym: "eyeball" EXACT [FMA:12513] synonym: "globe" RELATED [HP:0100886, MIAA:0000283] xref: FMA:12513 xref: MIAA:0000283 xref: SCTID:244486005 xref: VHOG:0001616 xref: Wikipedia:Globe_(human_eye) is_a: UBERON:0000020 ! sense organ is_a: UBERON:0004121 ! ectoderm-derived structure relationship: contributes_to_morphology_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0000019 {source="FMA"} ! camera-type eye property_value: IAO:0000232 "See notes for camera-type eye" xsd:string property_value: UBPROP:0000202 FMA:264089 [Term] id: UBERON:0010243 name: merocrine gland namespace: uberon def: "An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged." [MGI:anna, MP:0013544, Wikipedia:Merocrine] subset: pheno_slim xref: BTO:0002324 xref: MA:0003041 xref: Wikipedia:Merocrine is_a: UBERON:0002365 ! exocrine gland intersection_of: UBERON:0002365 ! exocrine gland intersection_of: capable_of GO:0006887 ! exocytosis relationship: capable_of GO:0006887 ! exocytosis property_value: UBPROP:0000007 "merocrine" xsd:string [Term] id: UBERON:0010252 name: 1st arch mandibular mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme." [OBOL:automatic] xref: EHDAA2:0000037 is_a: UBERON:0009584 ! 1st arch mandibular mesenchyme is_a: UBERON:0010259 {source="inferred"} ! 1st arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0009584 ! 1st arch mandibular mesenchyme relationship: develops_from UBERON:0007098 ! mandibular neural crest relationship: part_of UBERON:0009584 {source="EHDAA2"} ! 1st arch mandibular mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest [Term] id: UBERON:0010253 name: 1st arch maxillary mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme." [OBOL:automatic] xref: EHDAA2:0000044 is_a: UBERON:0010045 ! 1st arch maxillary mesenchyme is_a: UBERON:0010259 ! 1st arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010045 ! 1st arch maxillary mesenchyme relationship: part_of UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest [Term] id: UBERON:0010254 name: 2nd arch mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 2 mesenchyme from neural crest" RELATED [] synonym: "neural crest derived arch 2 mesenchyme" EXACT [] synonym: "pharyngeal arch 2 mesenchyme from neural crest" EXACT [] xref: EHDAA2:0000068 xref: EMAPA:16281 is_a: UBERON:0005689 ! 2nd arch mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0005689 ! 2nd arch mesenchyme relationship: develops_from UBERON:0007099 ! hyoid neural crest relationship: part_of UBERON:0005689 {source="EHDAA2"} ! 2nd arch mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest [Term] id: UBERON:0010255 name: 3rd arch mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme." [OBOL:automatic] synonym: "3rd pharyngeal arch mesenchyme derived from neural crest" EXACT [VHOG:0000571] synonym: "branchial arch 3 mesenchyme from neural crest" RELATED [] synonym: "mesenchyme derived from neural crest of mesenchyme of 3rd arch" EXACT [EMAPA:16404] synonym: "neural crest derived arch 3 mesenchyme" EXACT [] synonym: "pharyngeal arch 3 mesenchyme from neural crest" EXACT [] xref: EHDAA2:0000083 xref: EMAPA:16404 xref: VHOG:0000571 is_a: UBERON:0005690 ! 3rd arch mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0005690 ! 3rd arch mesenchyme relationship: part_of UBERON:0005690 {source="EHDAA2"} ! 3rd arch mesenchyme property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000571", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0010256 name: 4th arch mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme." [OBOL:automatic] synonym: "4th pharyngeal arch mesenchyme derived from neural crest" EXACT [VHOG:0000580] synonym: "branchial arch 4 mesenchyme from neural crest" RELATED [] synonym: "mesenchyme derived from neural crest of mesenchyme of 4th arch" EXACT [EMAPA:16772] synonym: "neural crest derived arch 4 mesenchyme" EXACT [] synonym: "pharyngeal arch 4 mesenchyme from neural crest" EXACT [] xref: EHDAA2:0000098 xref: EMAPA:16772 xref: VHOG:0000580 is_a: UBERON:0005691 ! 4th arch mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0005691 ! 4th arch mesenchyme relationship: part_of UBERON:0005691 {source="EHDAA2"} ! 4th arch mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest property_value: UBPROP:0000003 "In all vertebrates, the pharyngeal apparatus develops from a series of bulges found on the lateral surface of the head, the pharyngeal arches, which consist of a number of different embryonic cell types. Each arch has an external covering of ectoderm and inner covering of endoderm, and between these a mesenchymal filling of neural crest with a central core of mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000580", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0010257 name: 6th arch mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 6 mesenchyme from neural crest" RELATED [] synonym: "neural crest derived arch 6 mesenchyme" EXACT [] synonym: "pharyngeal arch 6 mesenchyme from neural crest" EXACT [] xref: EHDAA2:0004077 is_a: UBERON:0010031 ! 6th arch mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010031 ! 6th arch mesenchyme relationship: part_of UBERON:0010031 {source="EHDAA2"} ! 6th arch mesenchyme relationship: part_of UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest [Term] id: UBERON:0010258 name: mesenchyme from rhombencephalic neural crest namespace: uberon def: "Mesenchyme that develops_from a rhombencephalon neural crest." [OBOL:automatic] xref: EHDAA2:0004423 is_a: UBERON:0007213 ! mesenchyme derived from head neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0003852 ! rhombencephalon neural crest relationship: develops_from UBERON:0003852 ! rhombencephalon neural crest relationship: part_of UBERON:0007213 {source="EHDAA2"} ! mesenchyme derived from head neural crest [Term] id: UBERON:0010259 name: 1st arch mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 1 mesenchyme from neural crest" RELATED [] synonym: "mesenchyme derived from neural crest of mesenchyme of 1st arch" EXACT [EMAPA:16129] synonym: "neural crest derived arch 1 mesenchyme" EXACT [] synonym: "pharyngeal arch 1 mesenchyme from neural crest" EXACT [] xref: EMAPA:16129 is_a: UBERON:0010042 ! 1st arch mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest is_a: UBERON:0010359 ! pharyngeal arch mesenchyme from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010042 ! 1st arch mesenchyme relationship: part_of UBERON:0010042 ! 1st arch mesenchyme [Term] id: UBERON:0010260 name: umbilical blood vessel namespace: uberon def: "One of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton's jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta." [MP:0003230] subset: pheno_slim synonym: "allantoic vessel" EXACT [Hymans:Hymans] synonym: "umbilical cord blood vessel" EXACT [] synonym: "umbilical cord blood vessels" RELATED PLURAL [] synonym: "umbilical vasculature" RELATED [] synonym: "umbilical vessel" EXACT [] xref: EMAPA:36493 xref: SCTID:408728001 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: overlaps UBERON:0002331 ! umbilical cord relationship: located_in UBERON:0003422 ! mesenchyme of umbilical cord relationship: overlaps UBERON:0002331 ! umbilical cord [Term] id: UBERON:0010272 name: hyoid apparatus namespace: uberon def: "A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage." [http://www.biology-online.org/dictionary/Hyoid_apparatus] synonym: "apparatus hyobranchialis" RELATED LATIN [] synonym: "apparatus hyoideus" RELATED [http://www.biology-online.org/dictionary/Hyoid_apparatus] synonym: "hyobranchial apparatus" RELATED [AAO:0000225] synonym: "hyolingual system" RELATED [AAO:0000225] xref: AAO:0000225 xref: AAO:0000682 xref: EMAPA:37600 {source="MA:th"} xref: http://palaeos.com/vertebrates/bones/gill_arches/images/ReptileHyoids.gif xref: MA:0003037 xref: SCTID:410035009 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0005884 {source="AAO"} ! hyoid arch skeleton property_value: UBPROP:0000001 "Apparatus located in the floor of the mouth, under the mandibular arcade. The apparatus consists of a central corpus and four pairs of processes. This apparatus serves as the site of insertion for a variety of muscles associated with movements of the tongue and as the origin of the m. hyoglossus.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000225", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000002 "relationship loss: part_of hyolaryngeal complex (AAO:0000226)[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000225", ontology="AAO"} property_value: UBPROP:0000008 "In most mammals, including humans, the hyoid apparatus is shaped like a horseshoe. However, in humans, some of the bones of the hyoid apparatus are fused into a single bone called os hyoideum. In other animals such as frogs, the hyoid apparatus has a hyoid body that is chiefly comprised of hyaline cartilage and two pairs of processes (i.e. alary process and the posteriolateral process)." xsd:string [Term] id: UBERON:0010273 name: zone of hyoid bone namespace: uberon def: "A zone of bone organ that is part of a hyoid bone." [OBOL:automatic] synonym: "hyoid bone zone" EXACT [FMA:59494] xref: FMA:59494 xref: SCTID:119534005 is_a: UBERON:0005913 ! zone of bone organ intersection_of: UBERON:0005913 ! zone of bone organ intersection_of: part_of UBERON:0001685 ! hyoid bone relationship: part_of UBERON:0001685 ! hyoid bone [Term] id: UBERON:0010276 name: space in vertebral column namespace: uberon def: "Any anatomical space that is part of a vertebral column." [OBOL:automatic] synonym: "vertebral column opening" EXACT [AAO:0000700] synonym: "vertebral conduit" EXACT [] xref: AAO:0000700 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: part_of UBERON:0001130 ! vertebral column relationship: part_of UBERON:0001130 ! vertebral column [Term] id: UBERON:0010285 name: midbrain basal plate namespace: uberon def: "Portion of tissue that is dorsolateral to the floor plate and part of the midbrain." [ZFA:0000761] subset: efo_slim synonym: "basal plate midbrain" EXACT [TAO:0000761] synonym: "basal plate midbrain region" EXACT [ZFA:0000761] xref: DHBA:12322 xref: EFO:0003567 xref: EHDAA2:0004375 xref: TAO:0000761 xref: ZFA:0000761 is_a: UBERON:0002020 {source="EHDAA2"} ! gray matter relationship: part_of UBERON:0009581 {source="EHDAA2"} ! midbrain mantle layer relationship: part_of UBERON:0010286 {source="ZFA"} ! midbrain neural tube [Term] id: UBERON:0010286 name: midbrain neural tube namespace: uberon def: "Portion of neural tube that gives rise to the midbrain." [ZFA:0007039] xref: TAO:0007039 xref: ZFA:0007039 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue relationship: part_of UBERON:0003080 {source="ZFA"} ! anterior neural tube property_value: editor_note "we follow ZFA in temporally dividing midbrain NT from presumptive midbrain, but in future this may be collapsed" xsd:string [Term] id: UBERON:0010291 name: layer of sclera namespace: uberon def: "." [Wikipedia:Sclera#Histology] xref: Wikipedia:Sclera#Histology is_a: UBERON:0004923 ! organ component layer is_a: UBERON:0010313 ! neural crest-derived structure relationship: part_of UBERON:0001773 {source="cjm"} ! sclera [Term] id: UBERON:0010294 name: scleral endothelium namespace: uberon def: "An endothelium that is part of a sclera." [OBOL:automatic] is_a: UBERON:0001986 ! endothelium is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera is_a: UBERON:0015808 ! eye epithelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001773 ! sclera [Term] id: UBERON:0010295 name: substantia propria of sclera namespace: uberon def: "A stroma that is part of a sclera." [OBOL:automatic] synonym: "scleral stroma" EXACT [FMA:58365] synonym: "stroma of sclera" EXACT [FMA:58365] synonym: "subsantia propria" BROAD [] synonym: "subsantia propria sclerae" EXACT [FMA:58365] synonym: "substantia propria sclerae" EXACT LATIN [FMA:58365, FMA:TA] xref: FMA:58365 xref: NCIT:C33652 xref: SCTID:368851004 xref: UMLS:C1704397 {source="ncithesaurus:Substantia_Propria"} is_a: UBERON:0003891 ! stroma is_a: UBERON:0010291 {source="Wikipedia"} ! layer of sclera intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0001773 ! sclera [Term] id: UBERON:0010299 name: scleral mesenchyme namespace: uberon def: "Mesenchyme surrounding the developing optic cup which develops into the sclera." [https://orcid.org/0000-0002-6601-2165, PMID:16496288] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: has_potential_to_develop_into UBERON:0001773 ! sclera relationship: has_potential_to_develop_into UBERON:0001773 ! sclera relationship: surrounds UBERON:0003072 ! optic cup property_value: UBPROP:0000011 "The mesenchyme surrounding the developing optic cup differentiates into the sclera, the dense fibrous coat of the eye.. http://www.ncbi.nlm.nih.gov/pubmed/16496288" xsd:string [Term] id: UBERON:0010303 name: extraembryonic epithelium namespace: uberon def: "An epithelium that is part of a extraembryonic structure." [OBOL:automatic] synonym: "extra-embryonic epithelium" EXACT [] is_a: UBERON:0000483 ! epithelium is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000478 ! extraembryonic structure relationship: part_of UBERON:0000478 ! extraembryonic structure [Term] id: UBERON:0010304 name: non-keratinized stratified squamous epithelium namespace: uberon def: "Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus." [FMA:45569, Wikipedia:Stratified_squamous_epithelium#Nonkeratinized] synonym: "epithelium stratificatum squamosum noncornificatum" EXACT [FMA:45569] synonym: "nonkeratinizing stratified squamous epithelium" EXACT [FMA:45569] synonym: "stratified squamous non-keratinized epithelium" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "stratified squamous nonkeratinizing epithelium" EXACT [http://orcid.org/0000-0002-6601-2165] xref: FMA:45569 xref: Wikipedia:Stratified_squamous_epithelium#Nonkeratinized is_a: UBERON:0006915 {source="FMA"} ! stratified squamous epithelium disjoint_from: UBERON:0012329 ! keratinized stratified squamous epithelium [Term] id: UBERON:0010312 name: immature eye namespace: uberon def: "Developing anatomical structure that develops into the eyeball and associated structures." [ZFA:0001678] synonym: "future eye" EXACT [] xref: TAO:0002201 xref: ZFA:0001678 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: has_developmental_contribution_from UBERON:0003071 ! eye primordium relationship: develops_from UBERON:0003071 {evidence="definitional"} ! eye primordium relationship: has_developmental_contribution_from UBERON:0003071 ! eye primordium property_value: UBPROP:0000001 "Multi-tissue structure that consists of the structures that develop into the retina and lens.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0002201", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0010313 name: neural crest-derived structure namespace: uberon def: "An anatomical structure that develops from the neural crest." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0000061 ! anatomical structure intersection_of: develops_from UBERON:0002342 ! neural crest relationship: develops_from UBERON:0002342 ! neural crest property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0010314 name: structure with developmental contribution from neural crest namespace: uberon def: "An anatomical structure that has some part that develops from the neural crest." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: has_developmental_contribution_from UBERON:0002342 ! neural crest relationship: has_developmental_contribution_from UBERON:0002342 ! neural crest property_value: IAO:0000232 "Grouping term for query purposes" xsd:string [Term] id: UBERON:0010316 name: germ layer / neural crest namespace: uberon is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0005291 ! embryonic tissue relationship: develops_from UBERON:0002532 ! epiblast (generic) [Term] id: UBERON:0010321 name: skeletal element of eye region namespace: uberon def: "A skeletal element that is part of a orbital region." [OBOL:automatic] synonym: "eye skeleton" RELATED [] synonym: "ocular skeleton" RELATED [] synonym: "skeletal element of orbital region" RELATED [] is_a: UBERON:0004765 ! skeletal element is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0004765 ! skeletal element intersection_of: part_of UBERON:0004088 ! orbital region relationship: part_of UBERON:0004088 ! orbital region relationship: part_of UBERON:0011156 ! facial skeleton [Term] id: UBERON:0010323 name: cranial skeletal system namespace: uberon def: "Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000049] synonym: "cranial skeleton" NARROW [] synonym: "cranium" RELATED INCONSISTENT [ZFA:0000737] synonym: "osteocranium" NARROW [] xref: AAO:0000109 xref: AAO:0000971 xref: AAO:0010185 xref: TAO:0000737 xref: VSAO:0000049 xref: XAO:0003075 xref: ZFA:0000737 is_a: UBERON:0000075 ! subdivision of skeletal system relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of UBERON:0011137 ! axial skeletal system property_value: editor_note "we use 'cranial skeletal system', so that we can include the skull, which has joints/sutures as parts (recall, we follow FMA in distinguishing between the skeleton and skeletal system - only the latter includes joints)" xsd:string property_value: IAO:0000232 "that the cranial skeleton includes the pharyngeal arch skeleton. It is thus more inclusive that the cranium itself, and extends beyond the head in tetrapods. The AAO class called 'skull' belongs here, as it includes the whole splanchnocranium" xsd:string property_value: UBPROP:0000001 "Bony structure that encases the central nervous system and the primary sense organs of sight, olfaction, hearing, and equilibrium.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000109", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000001 "Skeletal system which is part of the skull, including the splanchnocranium, chondrocranium, and dermatocranium.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0000737", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0010328 name: limb bud mesenchyme namespace: uberon def: "Mesenchyme that is part of a limb bud." [OBOL:automatic] is_a: UBERON:0010329 ! paired limb/fin bud mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004347 ! limb bud relationship: part_of UBERON:0004347 ! limb bud [Term] id: UBERON:0010329 name: paired limb/fin bud mesenchyme namespace: uberon def: "Mesenchyme that is part of a limb/fin bud." [OBOL:automatic] is_a: UBERON:0010377 ! mesenchyme from somatopleure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004357 ! paired limb/fin bud relationship: develops_from UBERON:0010377 {source="EHDAA2-abduced"} ! mesenchyme from somatopleure relationship: part_of UBERON:0004357 ! paired limb/fin bud [Term] id: UBERON:0010332 name: epithelium of handplate namespace: uberon def: "An epithelium that is part of a handplate." [OBOL:automatic] synonym: "handplate epithelium" EXACT [EHDAA2:0000730] xref: EHDAA2:0000730 xref: EMAPA:32630 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006875 ! embryonic handplate relationship: develops_from UBERON:0003372 {source="EHDAA2"} ! pectoral appendage bud ectoderm relationship: part_of UBERON:0006875 ! embryonic handplate [Term] id: UBERON:0010333 name: extraembryonic membrane mesenchyme namespace: uberon def: "Mesenchyme that is part of a extraembryonic membrane." [OBOL:automatic] is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0005631 ! extraembryonic membrane relationship: develops_from UBERON:0005728 {source="EHDAA2-abduced"} ! extraembryonic mesoderm relationship: part_of UBERON:0005631 ! extraembryonic membrane [Term] id: UBERON:0010334 name: maxillary process mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme." [OBOL:automatic] xref: EHDAA2:0004601 is_a: UBERON:0009526 ! maxillary process mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0009526 ! maxillary process mesenchyme relationship: develops_from UBERON:0010253 {source="EHDAA2"} ! 1st arch maxillary mesenchyme from neural crest relationship: part_of UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme [Term] id: UBERON:0010335 name: maxillary process mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme." [OBOL:automatic] xref: EHDAA2:0004602 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0009526 ! maxillary process mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0009526 ! maxillary process mesenchyme relationship: develops_from UBERON:0010338 {source="EHDAA2"} ! 1st arch maxillary mesenchyme from head mesenchyme relationship: part_of UBERON:0009526 {source="EHDAA2"} ! maxillary process mesenchyme [Term] id: UBERON:0010336 name: mandibular process mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme." [OBOL:automatic] xref: EHDAA2:0004603 is_a: UBERON:0006905 ! mandibular process mesenchyme is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0006905 ! mandibular process mesenchyme relationship: develops_from UBERON:0010252 {source="EHDAA2"} ! 1st arch mandibular mesenchyme from neural crest relationship: part_of UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme [Term] id: UBERON:0010337 name: mandibular process mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme." [OBOL:automatic] xref: EHDAA2:0004604 is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0006905 ! mandibular process mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0006905 ! mandibular process mesenchyme relationship: develops_from UBERON:0010339 {source="EHDAA2"} ! 1st arch mandibular mesenchyme from head mesenchyme relationship: part_of UBERON:0006905 {source="EHDAA2"} ! mandibular process mesenchyme [Term] id: UBERON:0010338 name: 1st arch maxillary mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme." [OBOL:automatic] xref: EHDAA2:0000043 is_a: UBERON:0010045 ! 1st arch maxillary mesenchyme is_a: UBERON:0010341 ! 1st arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010045 ! 1st arch maxillary mesenchyme relationship: part_of UBERON:0010045 {source="EHDAA2"} ! 1st arch maxillary mesenchyme [Term] id: UBERON:0010339 name: 1st arch mandibular mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme." [OBOL:automatic] xref: EHDAA2:0000036 is_a: UBERON:0009584 ! 1st arch mandibular mesenchyme is_a: UBERON:0010341 ! 1st arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0009584 ! 1st arch mandibular mesenchyme relationship: part_of UBERON:0009584 {source="EHDAA2"} ! 1st arch mandibular mesenchyme [Term] id: UBERON:0010341 name: 1st arch mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme." [OBOL:automatic] synonym: "mesenchyme derived from head mesoderm of mesenchyme of 1st arch" EXACT [EMAPA:16130] xref: EMAPA:16130 is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0010042 ! 1st arch mesenchyme is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010042 ! 1st arch mesenchyme relationship: part_of UBERON:0010042 {source="EMAPA"} ! 1st arch mesenchyme [Term] id: UBERON:0010343 name: 2nd arch mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 2 mesenchyme from head mesenchyme" RELATED [] synonym: "head mesenchyme derived arch 2 mesenchyme" EXACT [] synonym: "mesenchyme derived from head mesoderm of mesenchyme of 2nd arch" EXACT [EMAPA:16280] synonym: "pharyngeal arch 2 mesenchyme from head mesenchyme" EXACT [] xref: EHDAA2:0000067 xref: EMAPA:16280 is_a: UBERON:0005689 ! 2nd arch mesenchyme is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0005689 ! 2nd arch mesenchyme relationship: part_of UBERON:0005689 {source="EHDAA2"} ! 2nd arch mesenchyme [Term] id: UBERON:0010344 name: 3rd arch mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 3 mesenchyme from head mesenchyme" RELATED [] synonym: "head mesenchyme derived arch 3 mesenchyme" EXACT [] synonym: "mesenchyme derived from head mesoderm of mesenchyme of 3rd arch" EXACT [EMAPA:16403] synonym: "pharyngeal arch 3 mesenchyme from head mesenchyme" EXACT [] xref: EHDAA2:0000082 xref: EMAPA:16403 is_a: UBERON:0005690 ! 3rd arch mesenchyme is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0005690 ! 3rd arch mesenchyme relationship: part_of UBERON:0005690 {source="EHDAA2"} ! 3rd arch mesenchyme [Term] id: UBERON:0010345 name: 4th arch mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 4 mesenchyme from head mesenchyme" RELATED [] synonym: "head mesenchyme derived arch 4 mesenchyme" EXACT [] synonym: "mesenchyme derived from head mesoderm of mesenchyme of 4th arch" EXACT [EMAPA:16771] synonym: "pharyngeal arch 4 mesenchyme from head mesenchyme" EXACT [] xref: EHDAA2:0000097 xref: EMAPA:16771 is_a: UBERON:0005691 ! 4th arch mesenchyme is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0005691 ! 4th arch mesenchyme relationship: part_of UBERON:0005691 {source="EHDAA2"} ! 4th arch mesenchyme [Term] id: UBERON:0010347 name: 6th arch mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme." [OBOL:automatic] synonym: "branchial arch 6 mesenchyme from head mesenchyme" RELATED [] synonym: "head mesenchyme derived arch 6 mesenchyme" EXACT [] synonym: "pharyngeal arch 6 mesenchyme from head mesenchyme" EXACT [] xref: EHDAA2:0004078 is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0010031 ! 6th arch mesenchyme is_a: UBERON:0010360 ! pharyngeal arch mesenchyme from head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010031 ! 6th arch mesenchyme relationship: part_of UBERON:0010031 {source="EHDAA2"} ! 6th arch mesenchyme [Term] id: UBERON:0010358 name: arch of centrum of vertebra namespace: uberon def: "An arch-shaped structure of the vertebra that extends dorsally (neural arch) or ventrally (hemal arch) from the vertebral centrum." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "arch of vertebra" NARROW [FMA:11946] synonym: "arcus vertebrae (vertebralis)" NARROW [FMA:11946] synonym: "vertebra arch" NARROW [MA:0001453] synonym: "vertebral arch" NARROW [FMA:11946] xref: EMAPA:36614 xref: FMA:11946 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004765 ! skeletal element relationship: part_of UBERON:0002412 {source="FMA"} ! vertebra property_value: UBPROP:0000003 "(...) certain common components [of vertebral structure] are found in nearly all vertebrate. A representative vertebra has a vertebral arch or neural arch, which extends dorsally around the spinal cord.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001670", ontology="VHOG", source="ISBN:978-0030223693 Liem KF, Bemis WE, Walker WF, Grande L, Functional Anatomy of the Vertebrates: An Evolutionary Perspective (2001) p.270", source="http://bgee.unil.ch/"} property_value: UBPROP:0000012 "Note that humans do not have hemal arches, so VA=NA for FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0010359 name: pharyngeal arch mesenchyme from neural crest namespace: uberon def: "Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme." [OBOL:automatic] comment: Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme synonym: "arch mesenchyme from neural crest" EXACT [] synonym: "branchial arch mesenchyme from neural crest" EXACT [] synonym: "neural crest derived arch mesenchyme" EXACT [] is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0014387 ! mesenchyme derived from neural crest intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest intersection_of: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme relationship: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme [Term] id: UBERON:0010360 name: pharyngeal arch mesenchyme from head mesenchyme namespace: uberon def: "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme." [OBOL:automatic] comment: Partially implements https://github.com/obophenotype/uberon/wiki/The-neural-crest NC meeting scheme synonym: "arch mesenchyme from head mesenchyme" EXACT [] synonym: "branchial arch mesenchyme from head mesenchyme" EXACT [] synonym: "head mesenchyme derived arch mesenchyme" EXACT [] is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0006904 ! head mesenchyme from mesoderm intersection_of: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme relationship: develops_from UBERON:0006904 ! head mesenchyme from mesoderm relationship: part_of UBERON:0010046 ! entire pharyngeal arch associated mesenchyme [Term] id: UBERON:0010362 name: endoskeleton namespace: uberon def: "Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000037] synonym: "replacement skeleton" EXACT [VSAO:curator] xref: VSAO:0000037 xref: Wikipedia:Endoskeleton xref: XAO:0004026 is_a: UBERON:0010912 {source="VSAO"} ! subdivision of skeleton relationship: composed_primarily_of UBERON:0010522 ! replacement element relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: UBPROP:0000001 "An endoskeleton is an internal support structure of an animal, composed of mineralized tissue. Endoskeleton develops within the skin or in the deeper body tissues. The vertebrate is basically an endoskeleton made up of two types of tissues (bone and cartilage). During early embryonic development the endoskeleton is composed of notochord and cartilage. The notochord in most vertebrates is replaced by vertebral column and cartilage is replaced by bone in most adults. In three phyla and one subclass of animals, endoskeletons of various complexity are found: Chordata, Echinodermata, Porifera, and Coleoidea. An endoskeleton may function purely for support (as in the case of sponges), but often serves as an attachment site for muscle and a mechanism for transmitting muscular forces. A true endoskeleton is derived from mesodermal tissue. Such a skeleton is present in echinoderms and chordates. The poriferan 'skeleton' consists of microscopic calcareous or siliceous spicules or a spongin network. The Coleoidae do not have a true endoskeleton in the evolutionary sense; here, a mollusk exoskeleton evolved into several sorts of internal structure, the 'cuttlebone' of cuttlefish being the best-known version. Yet they do have cartilaginous tissue in their body, even if it is not mineralized, especially in the head, where it forms a primitive cranium. The endoskeleton gives shape,support and protection to the body and provides a mean of locomotion.[Wikipedia:Endoskeleton]t" xsd:string {source="Wikipedia:Endoskeleton"} [Term] id: UBERON:0010363 name: endochondral element namespace: uberon def: "A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000139] synonym: "endochondral replacement element" EXACT [VSAO:0000139] xref: VSAO:0000139 xref: XAO:0004017 xref: ZFA:0005620 is_a: UBERON:0004765 {source="VSAO"} ! skeletal element property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern" xsd:anyURI [Term] id: UBERON:0010364 name: dermal skeleton namespace: uberon def: "Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000035] comment: This ontology covers metazoa, so we do not use exoskeleton as primary label, as in VSAO synonym: "dermal skeletal system" RELATED [VSAO:curator] synonym: "dermoskeleton" RELATED [VSAO:curator] synonym: "desmoskeleton" RELATED [VSAO:curator] synonym: "exoskeleton" BROAD INCONSISTENT [VSAO:curator] xref: VSAO:0000035 xref: XAO:0004025 is_a: UBERON:0010912 {source="VSAO"} ! subdivision of skeleton relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: UBERON:0010365 name: odontoid tissue namespace: uberon alt_id: UBERON:0001973 def: "Skeletal tissue that is part of the exoskeleton and derived from an odontogenic papilla." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000063] subset: uberon_slim synonym: "dental tissue" RELATED [VSAO:curator] synonym: "odontogenic tissue" EXACT [VSAO:curator] synonym: "portion of substance of tooth" NARROW [FMA:63001] synonym: "substance of tooth" NARROW [FMA:63001] synonym: "tooth hard tissue" RELATED [VT:0003930] synonym: "tooth substance" NARROW [MA:0002540] synonym: "tooth tissue" RELATED [] xref: EMAPA:35872 xref: FMA:63001 xref: MA:0002540 xref: NCIT:C33794 xref: UMLS:C1519551 {source="ncithesaurus:Tooth_Tissue"} xref: VSAO:0000063 xref: XAO:0004046 xref: ZFA:0005623 is_a: UBERON:0004755 ! skeletal tissue is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0004755 ! skeletal tissue intersection_of: develops_from UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0010364 ! dermal skeleton relationship: contributes_to_morphology_of UBERON:0001091 ! calcareous tooth relationship: develops_from UBERON:0001763 ! odontogenic papilla relationship: part_of UBERON:0001091 {gci_relation="part_of", gci_filler="NCBITaxon:32524"} ! calcareous tooth relationship: part_of UBERON:0010364 ! dermal skeleton property_value: UBPROP:0000008 "in many vertebrates, odontoid tissue is not restricted to the teeth" xsd:string property_value: UBPROP:0000012 "Classified as a portion of organism substance in FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0010368 name: pulmonary lobule namespace: uberon def: "The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa." [ncithesaurus:Pulmonary_Lobule] synonym: "lobulus pulmonis" EXACT LATIN [FMA:75739, FMA:TA] xref: FMA:75739 xref: NCIT:C33428 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0009911 ! lobule intersection_of: UBERON:0009911 ! lobule intersection_of: part_of UBERON:0002048 ! lung relationship: has_part UBERON:0002187 ! terminal bronchiole relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0010370 name: tibial vein namespace: uberon def: "One of the veins of the lower leg; empty into the popliteal vein." [http://www.thefreedictionary.com/tibial+vein] synonym: "vena tibialis" EXACT [] xref: EMAPA:37199 {source="MA:th"} xref: MA:0002243 xref: NCIT:C33787 xref: UMLS:C0447138 {source="ncithesaurus:Tibial_Vein"} is_a: UBERON:0001638 {source="MA"} ! vein is_a: UBERON:0003503 ! leg blood vessel [Term] id: UBERON:0010371 name: ecto-epithelium namespace: uberon def: "Epithelium composed of cells that develops from the ectoderm[FMA,modified]." [FMA:69064] synonym: "ectoderm-derived epithelium" EXACT [] xref: FMA:69064 is_a: UBERON:0000483 ! epithelium is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_from UBERON:0000924 ! ectoderm relationship: composed_primarily_of CL:0002077 ! ecto-epithelial cell [Term] id: UBERON:0010375 name: pancreas dorsal primordium namespace: uberon synonym: "dorsal pancreas" RELATED INCONSISTENT [FMA:79793] xref: EHDAA2:0001384 xref: FMA:79793 is_a: UBERON:0001048 ! primordium is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0009708 ! dorsal pancreas relationship: has_potential_to_develop_into UBERON:0009708 ! dorsal pancreas relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium property_value: editor_note "consider merging with dorsal pancreatic bud. Starts at CS12 in human (EHDAA2, embryology.ch 'bud anlagen')" xsd:string [Term] id: UBERON:0010376 name: pancreas ventral primordium namespace: uberon synonym: "ventral pancreas" RELATED INCONSISTENT [FMA:79794] xref: EHDAA2:0001387 xref: FMA:79794 is_a: UBERON:0001048 ! primordium is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0009709 ! ventral pancreas relationship: has_potential_to_develop_into UBERON:0009709 ! ventral pancreas relationship: part_of UBERON:0003921 {source="EHDAA2"} ! pancreas primordium property_value: UBPROP:0000008 "Starts at CS14 in human (EHDAA2) or CS13-14 (embryology.ch 'bud anlagen')" xsd:string [Term] id: UBERON:0010377 name: mesenchyme from somatopleure namespace: uberon def: "Mesenchyme that develops_from a somatopleure." [OBOL:automatic] xref: EHDAA2:0001120 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0004874 ! somatopleure intersection_of: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0004874 ! somatopleure relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme property_value: editor_note "the way this class is defined also includes extraembryonic mesenchyme such as the amniotic mesenchyme; in future this may be restricted to embryonic derivatives" xsd:string [Term] id: UBERON:0010378 name: mesenchyme from splanchnopleure namespace: uberon def: "Mesenchyme that develops_from a splanchnopleure." [OBOL:automatic] xref: EHDAA2:0001122 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007524 {source="EHDAA2"} ! dense mesenchyme tissue intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0004873 ! splanchnopleure intersection_of: part_of UBERON:0000922 ! embryo relationship: develops_from UBERON:0004873 ! splanchnopleure relationship: part_of UBERON:0009142 {source="EHDAA2"} ! entire embryonic mesenchyme [Term] id: UBERON:0010388 name: proximal segment of rib namespace: uberon def: "The segment of the rib that connects to a vertebra[MP]. a small part of the rib composed of the head, neck, tuberculum and a short proximal part of the body[PMID]." [MP:0000152, PMID:15906248] comment: The proximal rib derives from the caudal half of somite[PMID:15906248] subset: pheno_slim synonym: "costal part of rib" RELATED [] synonym: "proximal part of rib" EXACT [PMID:15906248] synonym: "proximal rib" EXACT [MA:0001400] synonym: "proximal rib segment" EXACT [] synonym: "vertebral part of rib" RELATED [] xref: EMAPA:37495 {source="MA:th"} xref: MA:0001400 xref: MA:0001414 is_a: UBERON:0005913 ! zone of bone organ relationship: connected_to UBERON:0002412 ! vertebra relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002228 {source="MA"} ! rib [Term] id: UBERON:0010390 name: lumen of urethra namespace: uberon def: "An organ cavity that is part of a urethra." [OBOL:automatic] synonym: "urethral lumen" EXACT [FMA:19709] xref: FMA:19709 xref: SCTID:279432008 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000057 ! urethra relationship: luminal_space_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0010399 name: spleen trabecular artery namespace: uberon def: "One of the branches of the splenic artery[MP]." [MP:0002354, Wikipedia:Trabecular_arteries] subset: human_reference_atlas subset: pheno_slim synonym: "trabecular artery" RELATED [] xref: MA:0000759 xref: NCIT:C49775 xref: UMLS:C1710159 {source="ncithesaurus:Splenic_Trabecular_Artery"} xref: Wikipedia:Trabecular_arteries is_a: UBERON:0003497 ! abdomen blood vessel is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0001265 ! trabecula of spleen relationship: branching_part_of UBERON:0001194 {source="MP"} ! splenic artery relationship: contributes_to_morphology_of UBERON:0002106 ! spleen relationship: part_of UBERON:0001194 ! splenic artery relationship: part_of UBERON:0001265 ! trabecula of spleen property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "When the splenic artery passes into the trabecula of the spleen and branches, they become known as the trabecular arteries. When these arteries then reach the white pulp, and become covered with Periarteriolar lymphoid sheaths, the name changes again to central arteries (or central arterioles). Branches of the central arteries are given to the red pulp, and these are called penicillar arteries).[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Trabecular_arteries"} [Term] id: UBERON:0010400 name: spleen trabecular vein namespace: uberon def: "One of the veins that feed the splenic vein." [MP:0002228, Wikipedia:Trabecular_veins] subset: human_reference_atlas subset: pheno_slim synonym: "trabecular vein" RELATED [Wikipedia:Trabecular_veins] xref: MA:0000760 xref: NCIT:C49779 xref: UMLS:C1710160 {source="ncithesaurus:Splenic_Trabecular_Vein"} xref: Wikipedia:Trabecular_veins is_a: UBERON:0013126 ! vein of abdomen intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001265 ! trabecula of spleen relationship: connected_to UBERON:0003713 ! splenic vein relationship: contributes_to_morphology_of UBERON:0002106 ! spleen relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001265 ! trabecula of spleen property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000001 "The trabecular veins are the largest veins inside the spleen. It drains the blood collected in the sinuses of the pulp.[Wikipedia]" xsd:string {ontology="Wikipedia", source="Wikipedia:Trabecular_veins"} [Term] id: UBERON:0010409 name: ocular surface region namespace: uberon def: "The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms." [MP:0013754] subset: pheno_slim synonym: "eye surface" EXACT [MA:0002486] synonym: "eye surface region" EXACT [] synonym: "ocular surface" EXACT [] xref: EMAPA:35336 xref: MA:0002486 is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004121 ! ectoderm-derived structure relationship: part_of UBERON:0000019 ! camera-type eye relationship: superficial_to UBERON:0022288 ! surface of eyeball [Term] id: UBERON:0010418 name: urethral opening namespace: uberon def: "An orifice that is part of a lower urinary tract." [OBOL:automatic] subset: pheno_slim synonym: "urethral orifice" EXACT [OBOL:automatic] xref: EMAPA:35965 xref: MA:0002867 is_a: UBERON:0000161 ! orifice intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0001556 ! lower urinary tract relationship: part_of UBERON:0001556 ! lower urinary tract [Term] id: UBERON:0010425 name: internal naris namespace: uberon def: "A naris that is located inside the nasal cavity and connects to the pharynx." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "choana" EXACT [] synonym: "choanae" RELATED PLURAL [] synonym: "internal choana" EXACT [] synonym: "internal nares" RELATED PLURAL [] synonym: "internal nostril" RELATED [] xref: NCIT:C32856 is_a: UBERON:0000003 ! naris intersection_of: UBERON:0000003 ! naris intersection_of: connects UBERON:0001707 ! nasal cavity intersection_of: connects UBERON:0006562 ! pharynx relationship: connects UBERON:0006562 ! pharynx relationship: only_in_taxon NCBITaxon:8287 ! Sarcopterygii property_value: UBPROP:0000007 "choanal" xsd:string property_value: UBPROP:0000008 "In humans the only internal naris is the posterior nasal aperture, which connects to the nasopharynx" xsd:string property_value: UBPROP:0000202 FMA:76585 [Term] id: UBERON:0010427 name: ciliary processes namespace: uberon def: "The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens." [Wikipedia:Ciliary_processes] synonym: "ciliary process" RELATED [Wikipedia:Ciliary_processes] synonym: "ciliary processes" EXACT [FMA:76551] synonym: "ciliary processes set" EXACT [FMA:76551] synonym: "processus ciliares" EXACT LATIN [FMA:TA] synonym: "processus ciliares" RELATED LATIN [Wikipedia:Ciliary_processes] synonym: "set of ciliary processes" EXACT [FMA:76551] xref: FMA:76551 xref: SCTID:280860001 xref: Wikipedia:Ciliary_processes is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: part_of UBERON:0001775 ! ciliary body property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b2/Gray875.png" xsd:anyURI [Term] id: UBERON:0010428 name: flat bone namespace: uberon def: "A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow." [Wikipedia:Flat_bone] comment: Examples: cranium, the ilium, sternum, rib cage, the sacrum and the scapula; the occipital, parietal, frontal, nasal, lacrimal, vomer, scapula, os coxC&, sternum, and ribs synonym: "os planum" RELATED LATIN [Wikipedia:Flat_bone] xref: FMA:7476 xref: galen:FlatBone xref: NCIT:C32616 xref: SCTID:332907008 xref: UMLS:C0222649 {source="ncithesaurus:Flat_Bone"} xref: Wikipedia:Flat_bone is_a: UBERON:0001474 {source="FMA"} ! bone element relationship: has_quality PATO:0000407 ! flat property_value: UBPROP:0000008 "In an adult mammal, most red blood cells are formed in flat bones" xsd:string property_value: UBPROP:0000009 "Flat bones are those bones which are found where the principal requirement is either extensive protection or the provision of broad surfaces for muscular attachment" xsd:string [Term] id: UBERON:0010498 name: pseudostratified columnar epithelium namespace: uberon def: "A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels." [http://medical-dictionary.thefreedictionary.com/pseudostratified+epithelium, Wikipedia:Pseudostratified_columnar_epithelium] xref: FMA:45572 xref: NCIT:C33419 xref: NCIT:C49316 xref: UMLS:C0836138 {source="ncithesaurus:Pseudostratified_Columnar_Epithelium"} xref: UMLS:C1514590 {source="ncithesaurus:Pseudostratified_Epithelium"} xref: Wikipedia:Pseudostratified_columnar_epithelium is_a: UBERON:0000485 {source="FMA"} ! simple columnar epithelium property_value: UBPROP:0000009 "Pseudostratified epithelia function in secretion or absorption. If a specimen looks stratified but has cilia, then it is a pseudostratified ciliated epithelium, since stratified epithelia do not have cilia." xsd:string property_value: UBPROP:0000012 "glandular in NCIT; we consider the two NCIT terms synonymous" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0010499 name: pseudostratified ciliated columnar epithelium namespace: uberon def: "Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile." [NCIT:NCIT] synonym: "epithelium pseudostratificatum columnare ciliatum (trachea et bronchi)" EXACT [FMA:13146] xref: FMA:13146 xref: NCIT:C13181 xref: UMLS:C0506992 {source="ncithesaurus:Pseudostratified_Columnar_Ciliated_Epithelium"} is_a: UBERON:0007592 ! ciliated columnar epithelium is_a: UBERON:0010498 ! pseudostratified columnar epithelium intersection_of: UBERON:0010498 ! pseudostratified columnar epithelium intersection_of: has_part CL:0000067 ! ciliated epithelial cell [Term] id: UBERON:0010521 name: electroreceptor organ namespace: uberon def: "An organ that is capable of detecting electrical stimulus." [http://orcid.org/0000-0002-6601-2165] synonym: "electric sense organ" EXACT [] synonym: "electroreception organ" EXACT [] is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000062 ! organ intersection_of: capable_of GO:0050964 ! detection of electrical stimulus involved in electroception relationship: capable_of GO:0050964 ! detection of electrical stimulus involved in electroception [Term] id: UBERON:0010522 name: replacement element namespace: uberon def: "Skeletal element that forms as a replacement or substitution of another element or tissue." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000135] xref: VSAO:0000135 xref: XAO:0004016 xref: ZFA:0005624 is_a: UBERON:0004765 {source="VSAO"} ! skeletal element relationship: part_of UBERON:0010362 {source="cjm"} ! endoskeleton [Term] id: UBERON:0010523 name: microcirculatory vessel namespace: uberon def: "A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses." [http://orcid.org/0000-0002-6601-2165, MESH:A07.231.432, ZFA:0005251] synonym: "microcirculatory vessels" RELATED PLURAL [TAO:0005251] xref: MESH:D055806 xref: TAO:0005251 xref: ZFA:0005251 is_a: UBERON:0000055 ! vessel relationship: part_of UBERON:0002049 {source="ZFA"} ! vasculature [Term] id: UBERON:0010527 name: cavity of bone organ namespace: uberon def: "An organ cavity that surrounded_by a bone." [OBOL:automatic] synonym: "bone organ cavity" EXACT [FMA:24021] xref: FMA:24021 is_a: UBERON:0002558 ! organ cavity intersection_of: UBERON:0002558 ! organ cavity intersection_of: part_of UBERON:0001474 ! bone element relationship: part_of UBERON:0001474 ! bone element [Term] id: UBERON:0010528 name: pneumatic cavity of bone namespace: uberon synonym: "air space of bone" EXACT [FMA:24028] xref: FMA:24028 is_a: UBERON:0010527 {source="FMA"} ! cavity of bone organ relationship: part_of UBERON:0008193 ! pneumatized bone [Term] id: UBERON:0010531 name: metanephros induced blastemal cells namespace: uberon synonym: "cap mesenchyme of metanephros of urinary system" RELATED [EMAPA:17645] synonym: "induced blastemal cells" EXACT [VHOG:0001241] synonym: "nephrogenic interstitium" RELATED [] synonym: "nephrogenic interstitium of nephrogenic zone" EXACT [EMAPA:17953] synonym: "peripheral blastema" RELATED [EMAPA:17953] xref: EHDAA2:0001143 xref: EHDAA:7007 xref: EHDAA:8105 xref: EMAPA:17953 xref: EMAPA:27621 xref: MA:0002998 xref: VHOG:0001241 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0005423 ! developing anatomical structure relationship: developmentally_induced_by UBERON:0000084 ! ureteric bud relationship: develops_from UBERON:0003220 {source="EHDAA2"} ! metanephric mesenchyme relationship: has_part CL:0000354 ! blastemal cell relationship: part_of UBERON:0009871 ! nephrogenic zone property_value: UBPROP:0000012 "different versions of EMAPA have different labels for the same classes. In vHOG this is part of metanephros cortex but this leads to a cycle in basic." xsd:string {external_ontology="EMAPA"} [Term] id: UBERON:0010532 name: primitive nephron namespace: uberon def: "An epithelial tube that is fated to become a nephron." [http://orcid.org/0000-0002-6601-2165] synonym: "developing nephron" BROAD [] synonym: "future nephron" EXACT [] synonym: "presumptive nephron" EXACT [] synonym: "primitive nephron" BROAD [] is_a: UBERON:0003914 {source="EHDAA2-inferred"} ! epithelial tube is_a: UBERON:0004819 ! kidney epithelium is_a: UBERON:0006555 ! excretory tube relationship: develops_from UBERON:0004209 {source="EHDAA2"} ! renal vesicle relationship: has_potential_to_develop_into UBERON:0001285 ! nephron relationship: located_in UBERON:0003918 ! kidney mesenchyme property_value: UBPROP:0000012 "EHDAA2 treats this as already having a tubular structure, but in the ZFA representation this is a cluster of cells" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0010533 name: metanephros cortex namespace: uberon def: "The metanephric cortex is the outer region of the metanephros[GO]." [GO:0072214] xref: VHOG:0000714 is_a: UBERON:0001225 ! cortex of kidney is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001225 ! cortex of kidney intersection_of: part_of UBERON:0000081 ! metanephros relationship: develops_from UBERON:0005113 ! metanephric cortex mesenchyme relationship: part_of UBERON:0000081 {source="VHOG"} ! metanephros [Term] id: UBERON:0010534 name: primitive mesonephric nephron namespace: uberon def: "Anatomical cluster which give rise to mature mesonephric nephrons. Zebrafish continously generate new mesonephric nephrons." [GOC:cvs, https://orcid.org/0000-0002-2244-7917, ZFA:0005584] synonym: "developing mesonephric nephron" EXACT [ZFA:0005584] synonym: "primitive mesonephric nephron" EXACT [] xref: ZFA:0005584 is_a: UBERON:0000083 ! mesonephric tubule is_a: UBERON:0010532 ! primitive nephron intersection_of: UBERON:0010532 ! primitive nephron intersection_of: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0010535 name: primitive metanephric nephron namespace: uberon def: "A primitive nephron that is part of a metanephros." [OBOL:automatic] synonym: "developing metanephric nephron" EXACT [] synonym: "primitive metanephric nephron" EXACT [] synonym: "primitive nephron" BROAD [EHDAA2:0001516] xref: EHDAA2:0001516 is_a: UBERON:0005106 ! metanephric tubule is_a: UBERON:0010532 ! primitive nephron intersection_of: UBERON:0010532 ! primitive nephron intersection_of: part_of UBERON:0000081 ! metanephros relationship: part_of UBERON:0005113 {source="EHDAA2"} ! metanephric cortex mesenchyme [Term] id: UBERON:0010536 name: nephron progenitor namespace: uberon is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000479 {source="ZFA"} ! tissue relationship: has_potential_to_develop_into UBERON:0001285 ! nephron relationship: part_of UBERON:0003918 {source="cjm"} ! kidney mesenchyme [Term] id: UBERON:0010537 name: mesonephric nephron progenitor namespace: uberon def: "Cluster of cells comprising a portion of tissue which gives rise to new mesonephric nephrons. The cluster contains self-renewing stem cells." [ZFA:0005587] xref: ZFA:0005587 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010536 ! nephron progenitor intersection_of: UBERON:0010536 ! nephron progenitor intersection_of: part_of UBERON:0000080 ! mesonephros relationship: part_of UBERON:0000080 ! mesonephros [Term] id: UBERON:0010538 name: paired limb/fin segment namespace: uberon def: "An appendage segment that is part of a limb/fin." [OBOL:automatic] subset: homology_grouping synonym: "limb/fin segment" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010758 ! subdivision of organism along appendicular axis intersection_of: UBERON:0010758 ! subdivision of organism along appendicular axis intersection_of: part_of UBERON:0004708 ! paired limb/fin disjoint_from: UBERON:0010912 ! subdivision of skeleton relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0004708 ! paired limb/fin [Term] id: UBERON:0010540 name: tarsus pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a tarsal bone." [OBOL:automatic] xref: EHDAA2:0001978 is_a: UBERON:0003328 ! mesenchyme of footplate is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0010695 ! mesenchyme of tarsal region is_a: UBERON:0015050 ! tarsus endochondral element intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0001447 ! tarsal bone relationship: develops_from UBERON:0010695 ! mesenchyme of tarsal region relationship: has_potential_to_develop_into UBERON:0001447 ! tarsal bone relationship: part_of UBERON:0003328 ! mesenchyme of footplate [Term] id: UBERON:0010541 name: tarsus cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a tarsal bone." [OBOL:automatic] xref: EHDAA2:0001977 is_a: UBERON:0003328 ! mesenchyme of footplate is_a: UBERON:0005863 ! cartilaginous condensation is_a: UBERON:0010695 ! mesenchyme of tarsal region is_a: UBERON:0015050 ! tarsus endochondral element intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: has_potential_to_develop_into UBERON:0001447 ! tarsal bone relationship: develops_from UBERON:0010540 {source="EHDAA2"} ! tarsus pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0001447 ! tarsal bone relationship: part_of UBERON:0003328 {source="EHDAA2"} ! mesenchyme of footplate [Term] id: UBERON:0010543 name: acropodial skeleton namespace: uberon def: "The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the autopodium - i.e. the bones of the digits or their cartilaginous precursors[VSAO,modified]." [https://orcid.org/0000-0002-6601-2165, VSAO:0005028, VSAO:NI] synonym: "acropodial skeleton" EXACT [] synonym: "acropodium" RELATED [VSAO:0005028, VSAO:NI] synonym: "acropodium skeleton" EXACT [] synonym: "digital skeleton" RELATED [] synonym: "digits skeleton" RELATED [] synonym: "phalangeal skeleton" RELATED [] synonym: "set of phalanges" EXACT [FMA:231315] synonym: "skeletal parts of acropodial region" EXACT [] synonym: "skeletal parts of acropodium" RELATED [] synonym: "skeleton of digits" RELATED [] xref: FMA:231315 xref: VSAO:0005028 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0012354 ! acropodium region relationship: has_part UBERON:0015023 ! phalanx endochondral element relationship: part_of UBERON:0012150 {source="PHENOSCAPE:ni"} ! skeleton of digitopodium relationship: part_of UBERON:0012354 ! acropodium region relationship: proximally_connected_to UBERON:0010546 ! metapodial skeleton relationship: skeleton_of UBERON:0012354 ! acropodium region [Term] id: UBERON:0010544 name: metacarpus skeleton namespace: uberon def: "The metacarpus is the intermediate part of the manus skeleton that is located between the phalanges (bones of the fingers) distally and the carpus which forms the connection to the forearm. The metacarpus consists of metacarpal bones. The metacarpals form a transverse arch to which the rigid row of distal carpal bones are fixed. The peripheral metacarpals (those of the thumb and little finger) form the sides of the cup of the palmar gutter and as they are brought together they deepen this concavity. The index metacarpal is the most firmly fixed, while the thumb metacarpal articulates with the trapezium and acts independently from the others. The middle metacarpals are tightly united to the carpus by intrinsic interlocking bone elements at their bases. The ring metacarpal forms a transitional element of the semi-independent last metacarpal. [WP,unvetted]." [Wikipedia:Metacarpus] synonym: "anterior metapodial skeleton" EXACT [] synonym: "anterior metapodium" RELATED [VSAO:0005026, VSAO:NI] synonym: "fore metapodial skeleton" RELATED [] synonym: "fore metapodium" RELATED [AAO:0000946, http://en.wiktionary.org/wiki/metapodial, MA:th] synonym: "metacarpal bones" EXACT [FMA:71336] synonym: "metacarpal skeleton" EXACT [] synonym: "metacarpalia" RELATED LATIN [Wikipedia:Metacarpus] synonym: "metacarpals [I-V]" EXACT [FMA:71336] synonym: "metacarpals set" EXACT [FMA:71336] synonym: "ossa metacarpalia [I-V]" EXACT LATIN [FMA:71336, FMA:TA] synonym: "ossa metacarpi [I-V]" EXACT LATIN [FMA:71336, FMA:TA] synonym: "set of metacarpal bones" EXACT [FMA:71336] synonym: "set of metacarpals" EXACT [FMA:71336] synonym: "set of metacarpals [I-V]" EXACT [FMA:71336] synonym: "skeleton of metacarpus" EXACT [] xref: AAO:0000946 xref: EMAPA:36158 xref: FMA:71336 xref: MESH:D050279 xref: VSAO:0005026 xref: Wikipedia:Metacarpus xref: XAO:0003208 is_a: UBERON:0010546 ! metapodial skeleton is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0004453 ! metacarpus region disjoint_from: UBERON:0010545 {source="lexical"} ! metatarsus skeleton relationship: develops_from UBERON:0010699 {notes="many to one"} ! manual digit metacarpus cartilage element relationship: proximally_connected_to UBERON:0009880 ! carpal skeleton relationship: skeleton_of UBERON:0004453 ! metacarpus region property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/2/2f/Metacarpals_numbered-en.svg" xsd:anyURI property_value: UBPROP:0000001 "Segment of the forearm corresponding to the metacarpus, which articulates with the carpals at one end and with the phalanges at the other end.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000946", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0010545 name: metatarsus skeleton namespace: uberon def: "Limb segment that consists of the long bones of the pes. The metatarsals are analogous to the metacarpal bones of the manus." [Wikipedia:Metatarsus] synonym: "metatarsal bones set" EXACT [FMA:71340] synonym: "metatarsal skeleton" EXACT [] synonym: "metatarsalia" RELATED [] synonym: "metatarsals [I-V]" EXACT [FMA:71340] synonym: "ossa metatarsalia" RELATED LATIN [Wikipedia:Metatarsus] synonym: "ossa metatarsalia [I-V]" EXACT LATIN [FMA:71340, FMA:TA] synonym: "ossa metatarsi[I-V]" EXACT LATIN [FMA:71340, FMA:TA] synonym: "posterior metapodial skeleton" EXACT [] synonym: "posterior metapodium" RELATED [VSAO:0005027, VSAO:NI] synonym: "set of metatarsal bones" EXACT [FMA:71340] synonym: "set of metatarsals [I-V]" EXACT [FMA:71340] synonym: "skeleton of metatarsus" EXACT [] xref: AAO:0000221 xref: FMA:71340 xref: MESH:D008684 xref: VSAO:0005027 xref: Wikipedia:Metatarsus xref: XAO:0003212 is_a: UBERON:0010546 ! metapodial skeleton is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0000983 ! metatarsus region relationship: develops_from UBERON:0010697 {notes="many to one"} ! pedal digit metatarsal cartilage element relationship: proximally_connected_to UBERON:0009879 ! tarsal skeleton relationship: skeleton_of UBERON:0000983 ! metatarsus region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/52/Gray291.png" xsd:anyURI property_value: UBPROP:0000001 "Segment of the leg corresponding to the metatarsus, which articulates with the carpals at one end and with the phalanges at the other end.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000221", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0010546 name: metapodial skeleton namespace: uberon def: "Subdivision of skeleton that corresponds to metapodium region, between acropodial skeleton and mesopdoial skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "metacarpal/metatarsal skeleton" EXACT [] synonym: "metapodial skeleton" EXACT [VSAO:0005025] synonym: "metapodium" RELATED [VSAO:0005025, VSAO:NI] synonym: "metapodium skeleton" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "skeletal parts of metapodium" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "skeleton of metapodium" EXACT [] xref: VSAO:0005025 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0009877 ! metapodium region relationship: distally_connected_to UBERON:0010543 ! acropodial skeleton relationship: part_of UBERON:0009877 ! metapodium region relationship: part_of UBERON:0012150 {source="PHENOSCAPE:ni"} ! skeleton of digitopodium relationship: proximally_connected_to UBERON:0009878 ! mesopodial skeleton relationship: skeleton_of UBERON:0009877 ! metapodium region property_value: UBPROP:0000001 "Endochondral bone complex located between the mesopodium and the acropodium and consisting of the metacarpals or metatarsals.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0005025", ontology="VSAO", source="VSAO:NI"} property_value: UBPROP:0000002 "relationship type change: subclass skeletal subdivision (VSAO:0000042) CHANGED TO: connected_to subdivision of skeleton (UBERON:0010912)[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0005025", ontology="VSAO"} property_value: UBPROP:0000002 "relationship type change: subclass skeletal subdivision (VSAO:0000042) CHANGED TO: distally_connected_to subdivision of skeleton (UBERON:0010912)[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0005025", ontology="VSAO"} [Term] id: UBERON:0010547 name: pedal digit 1 metatarsal pre-cartilage condensation namespace: uberon def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] synonym: "foot digit 1 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit I metatarsal pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 1 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002040] xref: EHDAA2:0002040 xref: EMAPA:17725 is_a: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation is_a: UBERON:0015037 ! pedal digit 1 metatarsal endochondral element intersection_of: UBERON:0015037 ! pedal digit 1 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010548 name: pedal digit 2 metatarsal pre-cartilage condensation namespace: uberon def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] synonym: "foot digit 2 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit II metatarsal pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 2 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002045] xref: EHDAA2:0002045 xref: EMAPA:17727 is_a: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation is_a: UBERON:0015038 ! pedal digit 2 metatarsal endochondral element intersection_of: UBERON:0015038 ! pedal digit 2 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010549 name: pedal digit 3 metatarsal pre-cartilage condensation namespace: uberon def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] synonym: "foot digit 3 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit III metatarsal pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 3 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002050] xref: EHDAA2:0002050 xref: EMAPA:17729 is_a: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation is_a: UBERON:0015039 ! pedal digit 3 metatarsal endochondral element intersection_of: UBERON:0015039 ! pedal digit 3 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010550 name: pedal digit 4 metatarsal pre-cartilage condensation namespace: uberon def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] synonym: "foot digit 4 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit IV metatarsal pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 4 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002055] xref: EHDAA2:0002055 xref: EMAPA:17731 is_a: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation is_a: UBERON:0015040 ! pedal digit 4 metatarsal endochondral element intersection_of: UBERON:0015040 ! pedal digit 4 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010551 name: pedal digit 5 metatarsal pre-cartilage condensation namespace: uberon def: "A pedal digit metatarsal pre-cartilage condensation that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] synonym: "foot digit 5 metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit V metatarsal pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 5 metatarsal pre-cartilage condensation" EXACT [EHDAA2:0002060] xref: EHDAA2:0002060 xref: EMAPA:17733 is_a: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation is_a: UBERON:0015041 ! pedal digit 5 metatarsal endochondral element intersection_of: UBERON:0015041 ! pedal digit 5 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010557 name: pedal digit 1 metatarsal cartilage element namespace: uberon def: "A pedal digit metatarsal cartilage condensation that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] synonym: "foot digit 1 metatarsal cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 metatarsal cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit I metatarsal cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 1 metatarsal cartilage condensation" EXACT [] xref: EMAPA:18106 is_a: UBERON:0010697 ! pedal digit metatarsal cartilage element is_a: UBERON:0015037 ! pedal digit 1 metatarsal endochondral element intersection_of: UBERON:0015037 ! pedal digit 1 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010547 ! pedal digit 1 metatarsal pre-cartilage condensation [Term] id: UBERON:0010558 name: pedal digit 2 metatarsal cartilage element namespace: uberon def: "A pedal digit metatarsal cartilage element that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] synonym: "foot digit 2 metatarsal cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 metatarsal cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit II metatarsal cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 2 metatarsal cartilage element" EXACT [] xref: EMAPA:18111 is_a: UBERON:0010697 ! pedal digit metatarsal cartilage element is_a: UBERON:0015038 ! pedal digit 2 metatarsal endochondral element intersection_of: UBERON:0015038 ! pedal digit 2 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010548 ! pedal digit 2 metatarsal pre-cartilage condensation [Term] id: UBERON:0010559 name: pedal digit 3 metatarsal cartilage element namespace: uberon def: "A pedal digit metatarsal cartilage element that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] synonym: "foot digit 3 metatarsal cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 metatarsal cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit III metatarsal cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 3 metatarsal cartilage element" EXACT [] xref: EMAPA:18116 is_a: UBERON:0010697 ! pedal digit metatarsal cartilage element is_a: UBERON:0015039 ! pedal digit 3 metatarsal endochondral element intersection_of: UBERON:0015039 ! pedal digit 3 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010549 ! pedal digit 3 metatarsal pre-cartilage condensation [Term] id: UBERON:0010560 name: pedal digit 4 metatarsal cartilage element namespace: uberon def: "A pedal digit metatarsal cartilage element that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] synonym: "foot digit 4 metatarsal cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 metatarsal cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit IV metatarsal cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 4 metatarsal cartilage element" EXACT [] xref: EMAPA:18121 is_a: UBERON:0010697 ! pedal digit metatarsal cartilage element is_a: UBERON:0015040 ! pedal digit 4 metatarsal endochondral element intersection_of: UBERON:0015040 ! pedal digit 4 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010550 ! pedal digit 4 metatarsal pre-cartilage condensation [Term] id: UBERON:0010561 name: pedal digit 5 metatarsal cartilage element namespace: uberon def: "A pedal digit metatarsal cartilage element that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] synonym: "foot digit 5 metatarsal cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 metatarsal cartilage element" EXACT [OBOL:accepted] synonym: "pedal digit V metatarsal cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "toe 5 metatarsal cartilage element" EXACT [] xref: EMAPA:18126 is_a: UBERON:0010697 ! pedal digit metatarsal cartilage element is_a: UBERON:0015041 ! pedal digit 5 metatarsal endochondral element intersection_of: UBERON:0015041 ! pedal digit 5 metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010551 ! pedal digit 5 metatarsal pre-cartilage condensation [Term] id: UBERON:0010562 name: pedal digit 1 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing pedal digit 1." [OBOL:automatic] synonym: "foot digit 1 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 mesenchyme" EXACT [OBOL:accepted] synonym: "pedal digit I mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002039 xref: EMAPA:17462 is_a: UBERON:0005255 ! pedal digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: part_of UBERON:0003631 ! pedal digit 1 [Term] id: UBERON:0010564 name: manual digit 1 mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing manual digit 1." [OBOL:automatic] synonym: "fore limb digit 1 mesenchyme" EXACT [OBOL:accepted] synonym: "hand digit 1 mesenchyme" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit I mesenchyme" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000513 xref: EMAPA:17431 is_a: UBERON:0005257 ! manual digit mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: part_of UBERON:0001463 ! manual digit 1 [Term] id: UBERON:0010565 name: manual digit 1 metacarpus pre-cartilage condensation namespace: uberon def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 1 mesenchyme." [OBOL:automatic] synonym: "finger 1 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000515] synonym: "fore limb digit 1 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 1 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit I metacarpus pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal 1 pre-cartilage condensation" EXACT [] xref: EHDAA2:0000515 xref: EMAPA:17714 is_a: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation is_a: UBERON:0015043 ! manual digit 1 metacarpus endochondral element intersection_of: UBERON:0015043 ! manual digit 1 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010566 name: manual digit 2 metacarpus pre-cartilage condensation namespace: uberon def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 2 mesenchyme." [OBOL:automatic] synonym: "finger 2 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000521] synonym: "fore limb digit 2 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 2 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit II metacarpus pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal 2 pre-cartilage condensation" EXACT [] xref: EHDAA2:0000521 xref: EMAPA:17716 is_a: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation is_a: UBERON:0015044 ! manual digit 2 metacarpus endochondral element intersection_of: UBERON:0015044 ! manual digit 2 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010567 name: manual digit 3 metacarpus pre-cartilage condensation namespace: uberon def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 3 mesenchyme." [OBOL:automatic] synonym: "finger 3 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000527] synonym: "fore limb digit 3 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 3 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit III metacarpus pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal 3 pre-cartilage condensation" EXACT [] xref: EHDAA2:0000527 xref: EMAPA:17718 is_a: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation is_a: UBERON:0015045 ! manual digit 3 metacarpus endochondral element intersection_of: UBERON:0015045 ! manual digit 3 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010568 name: manual digit 4 metacarpus pre-cartilage condensation namespace: uberon def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 4 mesenchyme." [OBOL:automatic] synonym: "finger 4 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000533] synonym: "fore limb digit 4 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 4 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit IV metacarpus pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal 4 pre-cartilage condensation" EXACT [] xref: EHDAA2:0000533 xref: EMAPA:17720 is_a: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation is_a: UBERON:0015046 ! manual digit 4 metacarpus endochondral element intersection_of: UBERON:0015046 ! manual digit 4 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010569 name: manual digit 5 metacarpus pre-cartilage condensation namespace: uberon def: "A manual digit metacarpus pre-cartilage condensation that is part of a manual digit 5 mesenchyme." [OBOL:automatic] synonym: "finger 5 metacarpus pre-cartilage condensation" EXACT [EHDAA2:0000539] synonym: "fore limb digit 5 metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 5 metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit V metacarpus pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpal 5 pre-cartilage condensation" EXACT [] xref: EHDAA2:0000539 xref: EMAPA:17722 is_a: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation is_a: UBERON:0015047 ! manual digit 5 metacarpus endochondral element intersection_of: UBERON:0015047 ! manual digit 5 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010570 name: manual digit 1 metacarpus cartilage element namespace: uberon def: "A manual digit metacarpus cartilage element that is part of a manual digit 1 mesenchyme." [OBOL:automatic] synonym: "finger 1 metacarpus cartilage element" EXACT [EHDAA2:0000514] synonym: "fore limb digit 1 metacarpus cartilage element" EXACT [OBOL:accepted] synonym: "hand digit 1 metacarpus cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit I metacarpus cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpus 1 cartilage element" EXACT [] xref: EHDAA2:0000514 xref: EMAPA:18065 is_a: UBERON:0010699 ! manual digit metacarpus cartilage element is_a: UBERON:0015043 ! manual digit 1 metacarpus endochondral element intersection_of: UBERON:0015043 ! manual digit 1 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010565 ! manual digit 1 metacarpus pre-cartilage condensation [Term] id: UBERON:0010571 name: manual digit 2 metacarpus cartilage element namespace: uberon def: "A manual digit metacarpus cartilage element that is part of a manual digit 2 mesenchyme." [OBOL:automatic] synonym: "finger 2 metacarpus cartilage element" EXACT [EHDAA2:0000520] synonym: "fore limb digit 2 metacarpus cartilage element" EXACT [OBOL:accepted] synonym: "hand digit 2 metacarpus cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit II metacarpus cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpus 2 cartilage element" EXACT [] xref: EHDAA2:0000520 xref: EMAPA:18070 is_a: UBERON:0010699 ! manual digit metacarpus cartilage element is_a: UBERON:0015044 ! manual digit 2 metacarpus endochondral element intersection_of: UBERON:0015044 ! manual digit 2 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010566 ! manual digit 2 metacarpus pre-cartilage condensation [Term] id: UBERON:0010572 name: manual digit 3 metacarpus cartilage element namespace: uberon def: "A manual digit metacarpus cartilage element that is part of a manual digit 3 mesenchyme." [OBOL:automatic] synonym: "finger 3 metacarpus cartilage element" EXACT [EHDAA2:0000526] synonym: "fore limb digit 3 metacarpus cartilage element" EXACT [OBOL:accepted] synonym: "hand digit 3 metacarpus cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit III metacarpus cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpus 3 cartilage element" EXACT [] xref: EHDAA2:0000526 xref: EMAPA:18075 is_a: UBERON:0010699 ! manual digit metacarpus cartilage element is_a: UBERON:0015045 ! manual digit 3 metacarpus endochondral element intersection_of: UBERON:0015045 ! manual digit 3 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010567 ! manual digit 3 metacarpus pre-cartilage condensation [Term] id: UBERON:0010573 name: manual digit 4 metacarpus cartilage element namespace: uberon def: "A manual digit metacarpus cartilage element that is part of a manual digit 4 mesenchyme." [OBOL:automatic] synonym: "finger 4 metacarpus cartilage condensation" EXACT [EHDAA2:0000532] synonym: "fore limb digit 4 metacarpus cartilage element" EXACT [OBOL:accepted] synonym: "hand digit 4 metacarpus cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit IV metacarpus cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpus 4 cartilage element" EXACT [] xref: EHDAA2:0000532 xref: EMAPA:18080 is_a: UBERON:0010699 ! manual digit metacarpus cartilage element is_a: UBERON:0015046 ! manual digit 4 metacarpus endochondral element intersection_of: UBERON:0015046 ! manual digit 4 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010568 ! manual digit 4 metacarpus pre-cartilage condensation [Term] id: UBERON:0010574 name: manual digit 5 metacarpus cartilage element namespace: uberon def: "A manual digit metacarpus cartilage element that is part of a manual digit 5 mesenchyme." [OBOL:automatic] synonym: "finger 5 metacarpus cartilage condensation" EXACT [EHDAA2:0000538] synonym: "fore limb digit 5 metacarpus cartilage element" EXACT [OBOL:accepted] synonym: "hand digit 5 metacarpus cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit V metacarpus cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "metacarpus 5 cartilage element" EXACT [] xref: EHDAA2:0000538 xref: EMAPA:18085 is_a: UBERON:0010699 ! manual digit metacarpus cartilage element is_a: UBERON:0015047 ! manual digit 5 metacarpus endochondral element intersection_of: UBERON:0015047 ! manual digit 5 metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010569 ! manual digit 5 metacarpus pre-cartilage condensation [Term] id: UBERON:0010575 name: manual digit 1 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a manual digit 1 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 1 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 1 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit I phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000516 xref: EMAPA:17715 is_a: UBERON:0010586 ! manual digit phalanx pre-cartilage condensation is_a: UBERON:0015025 ! manual digit 1 phalanx endochondral element intersection_of: UBERON:0015025 ! manual digit 1 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010576 name: manual digit 2 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a manual digit 2 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 2 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 2 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit II phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000522 xref: EMAPA:17717 is_a: UBERON:0010586 ! manual digit phalanx pre-cartilage condensation is_a: UBERON:0015026 ! manual digit 2 phalanx endochondral element intersection_of: UBERON:0015026 ! manual digit 2 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010577 name: manual digit 3 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a manual digit 3 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 3 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 3 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit III phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000528 xref: EMAPA:17719 is_a: UBERON:0010586 ! manual digit phalanx pre-cartilage condensation is_a: UBERON:0015027 ! manual digit 3 phalanx endochondral element intersection_of: UBERON:0015027 ! manual digit 3 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010578 name: manual digit 4 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a manual digit 4 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 4 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 4 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit IV phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000534 xref: EMAPA:17721 is_a: UBERON:0010586 ! manual digit phalanx pre-cartilage condensation is_a: UBERON:0015028 ! manual digit 4 phalanx endochondral element intersection_of: UBERON:0015028 ! manual digit 4 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010579 name: manual digit 5 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a manual digit 5 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 5 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 5 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit V phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000540 xref: EMAPA:17723 is_a: UBERON:0010586 ! manual digit phalanx pre-cartilage condensation is_a: UBERON:0015029 ! manual digit 5 phalanx endochondral element intersection_of: UBERON:0015029 ! manual digit 5 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010580 name: pedal digit 1 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] synonym: "foot digit 1 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit I phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002041 xref: EMAPA:17726 is_a: UBERON:0010585 ! pedal digit phalanx pre-cartilage condensation is_a: UBERON:0015031 ! pedal digit 1 phalanx endochondral element intersection_of: UBERON:0015031 ! pedal digit 1 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010581 name: pedal digit 2 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] synonym: "foot digit 2 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit II phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002046 xref: EMAPA:17728 is_a: UBERON:0010585 ! pedal digit phalanx pre-cartilage condensation is_a: UBERON:0015032 ! pedal digit 2 phalanx endochondral element intersection_of: UBERON:0015032 ! pedal digit 2 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010582 name: pedal digit 3 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] synonym: "foot digit 3 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit III phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002051 xref: EMAPA:17730 is_a: UBERON:0010585 ! pedal digit phalanx pre-cartilage condensation is_a: UBERON:0015033 ! pedal digit 3 phalanx endochondral element intersection_of: UBERON:0015033 ! pedal digit 3 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010583 name: pedal digit 4 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] synonym: "foot digit 4 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit IV phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002056 xref: EMAPA:17732 is_a: UBERON:0010585 ! pedal digit phalanx pre-cartilage condensation is_a: UBERON:0015034 ! pedal digit 4 phalanx endochondral element intersection_of: UBERON:0015034 ! pedal digit 4 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010584 name: pedal digit 5 phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] synonym: "foot digit 5 phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit V phalanx pre-cartilage condensation" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002061 xref: EMAPA:17734 is_a: UBERON:0010585 ! pedal digit phalanx pre-cartilage condensation is_a: UBERON:0015035 ! pedal digit 5 phalanx endochondral element intersection_of: UBERON:0015035 ! pedal digit 5 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010585 name: pedal digit phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a pedal digit mesenchyme." [OBOL:automatic] synonym: "foot digit phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "foot phalanx pre-cartilage condensation" EXACT [VHOG:0000952] synonym: "hind limb digit phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hindlimb phalanx pre-cartilage condensation" EXACT [] synonym: "pes phalanx pre-cartilage condensation" EXACT [] xref: EMAPA:32950 xref: VHOG:0000952 is_a: UBERON:0010700 ! phalanx pre-cartilage condensation is_a: UBERON:0010886 ! hindlimb pre-cartilage condensation is_a: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010586 name: manual digit phalanx pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that is part of a manual digit mesenchyme." [OBOL:automatic] synonym: "fore limb digit phalanx pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "forelimb phalanx pre-cartilage condensation" EXACT [] synonym: "hand digit phalanx pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hand phalanx pre-cartilage condensation" EXACT [VHOG:0000954] synonym: "manus phalanx pre-cartilage condensation" EXACT [] xref: EMAPA:32639 xref: VHOG:0000954 is_a: UBERON:0010700 ! phalanx pre-cartilage condensation is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010675 name: manual digit 1 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a manual digit 1 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 1 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 1 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit I phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18066 is_a: UBERON:0010686 ! manual digit phalanx cartilage element is_a: UBERON:0015025 ! manual digit 1 phalanx endochondral element intersection_of: UBERON:0015025 ! manual digit 1 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010575 ! manual digit 1 phalanx pre-cartilage condensation [Term] id: UBERON:0010676 name: manual digit 2 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a manual digit 2 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 2 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 2 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit II phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18071 is_a: UBERON:0010686 ! manual digit phalanx cartilage element is_a: UBERON:0015026 ! manual digit 2 phalanx endochondral element intersection_of: UBERON:0015026 ! manual digit 2 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010576 ! manual digit 2 phalanx pre-cartilage condensation [Term] id: UBERON:0010677 name: manual digit 3 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a manual digit 3 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 3 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 3 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit III phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18076 is_a: UBERON:0010686 ! manual digit phalanx cartilage element is_a: UBERON:0015027 ! manual digit 3 phalanx endochondral element intersection_of: UBERON:0015027 ! manual digit 3 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010577 ! manual digit 3 phalanx pre-cartilage condensation [Term] id: UBERON:0010678 name: manual digit 4 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a manual digit 4 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 4 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 4 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit IV phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18081 is_a: UBERON:0010686 ! manual digit phalanx cartilage element is_a: UBERON:0015028 ! manual digit 4 phalanx endochondral element intersection_of: UBERON:0015028 ! manual digit 4 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010578 ! manual digit 4 phalanx pre-cartilage condensation [Term] id: UBERON:0010679 name: manual digit 5 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a manual digit 5 mesenchyme." [OBOL:automatic] synonym: "fore limb digit 5 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit 5 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit V phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18086 is_a: UBERON:0010686 ! manual digit phalanx cartilage element is_a: UBERON:0015029 ! manual digit 5 phalanx endochondral element intersection_of: UBERON:0015029 ! manual digit 5 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010579 ! manual digit 5 phalanx pre-cartilage condensation [Term] id: UBERON:0010680 name: pedal digit 1 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a pedal digit 1 mesenchyme." [OBOL:automatic] synonym: "foot digit 1 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit I phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18107 is_a: UBERON:0010685 ! pedal digit phalanx cartilage element is_a: UBERON:0015031 ! pedal digit 1 phalanx endochondral element intersection_of: UBERON:0015031 ! pedal digit 1 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010580 ! pedal digit 1 phalanx pre-cartilage condensation [Term] id: UBERON:0010681 name: pedal digit 2 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a pedal digit 2 mesenchyme." [OBOL:automatic] synonym: "foot digit 2 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 2 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit II phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18112 is_a: UBERON:0010685 ! pedal digit phalanx cartilage element is_a: UBERON:0015032 ! pedal digit 2 phalanx endochondral element intersection_of: UBERON:0015032 ! pedal digit 2 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010581 ! pedal digit 2 phalanx pre-cartilage condensation [Term] id: UBERON:0010682 name: pedal digit 3 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a pedal digit 3 mesenchyme." [OBOL:automatic] synonym: "foot digit 3 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 3 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit III phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18117 is_a: UBERON:0010685 ! pedal digit phalanx cartilage element is_a: UBERON:0015033 ! pedal digit 3 phalanx endochondral element intersection_of: UBERON:0015033 ! pedal digit 3 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010582 ! pedal digit 3 phalanx pre-cartilage condensation [Term] id: UBERON:0010683 name: pedal digit 4 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a pedal digit 4 mesenchyme." [OBOL:automatic] synonym: "foot digit 4 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 4 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit IV phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18122 is_a: UBERON:0010685 ! pedal digit phalanx cartilage element is_a: UBERON:0015034 ! pedal digit 4 phalanx endochondral element intersection_of: UBERON:0015034 ! pedal digit 4 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010583 ! pedal digit 4 phalanx pre-cartilage condensation [Term] id: UBERON:0010684 name: pedal digit 5 phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a pedal digit 5 mesenchyme." [OBOL:automatic] synonym: "foot digit 5 phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 5 phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "pedal digit V phalanx cartilage element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EMAPA:18127 is_a: UBERON:0010685 ! pedal digit phalanx cartilage element is_a: UBERON:0015035 ! pedal digit 5 phalanx endochondral element intersection_of: UBERON:0015035 ! pedal digit 5 phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010584 ! pedal digit 5 phalanx pre-cartilage condensation [Term] id: UBERON:0010685 name: pedal digit phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a pedal digit mesenchyme." [OBOL:automatic] synonym: "foot digit phalanx cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit phalanx cartilage condensation" EXACT [OBOL:accepted] xref: EMAPA:32948 is_a: UBERON:0010701 ! phalanx cartilage element is_a: UBERON:0015030 ! pedal digit phalanx endochondral element is_a: UBERON:0035129 ! pes cartilage element intersection_of: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010585 ! pedal digit phalanx pre-cartilage condensation [Term] id: UBERON:0010686 name: manual digit phalanx cartilage element namespace: uberon def: "A cartilage element that is part of a manual digit mesenchyme." [OBOL:automatic] synonym: "fore limb digit phalanx cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit phalanx cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] xref: EMAPA:32658 is_a: UBERON:0010701 ! phalanx cartilage element is_a: UBERON:0015024 ! manual digit phalanx endochondral element is_a: UBERON:0035128 ! manus cartilage element intersection_of: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010586 ! manual digit phalanx pre-cartilage condensation [Term] id: UBERON:0010687 name: pedal digit metatarsal pre-cartilage condensation namespace: uberon synonym: "foot digit metatarsal pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit metatarsal pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "metatarsal bone pre-cartilage condensation" EXACT [] synonym: "metatarsal pre-cartilage condensation" RELATED [EMAPA:32956] synonym: "metatarsus pre-cartilage condensation" EXACT [VHOG:0000948] xref: EMAPA:32956 xref: EMAPA:35568 xref: VHOG:0000948 is_a: UBERON:0003860 ! hindlimb mesenchyme is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0010886 ! hindlimb pre-cartilage condensation is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010688 name: skeleton of manual acropodium namespace: uberon def: "The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the manual autopodium - i.e. the bones of the hands or their cartilaginous precursors[VSAO,modified]." [https://orcid.org/0000-0002-6601-2165, VSAO:0005029, VSAO:NI] synonym: "all phalanges in forelimb autopod" EXACT [] synonym: "anterior acropodium" RELATED [VSAO:0005029, VSAO:NI] synonym: "anterior acropodium skeleton" EXACT [] synonym: "fore acropodium skeleton" EXACT [] synonym: "hand digit skeleton" EXACT [] synonym: "manual digit skeleton" EXACT [] synonym: "manual phalanges" EXACT PLURAL [VSAO:0005029, VSAO:NI] synonym: "phalanges of hand" EXACT [FMA:71337] synonym: "phalanges of manus" EXACT [] synonym: "set of manual phalanges" EXACT [] synonym: "set of phalanges of hand" EXACT [FMA:71337] synonym: "set of phalanges of manus" EXACT [] xref: FMA:71337 xref: VSAO:0005029 xref: Wikipedia:Phalanges_of_the_hand is_a: UBERON:0010543 ! acropodial skeleton intersection_of: UBERON:0010543 ! acropodial skeleton intersection_of: part_of UBERON:0002398 ! manus disjoint_from: UBERON:0010696 {source="lexical"} ! skeleton of pedal acropodium relationship: part_of UBERON:0012151 {source="PHENOSCAPE:ni"} ! skeleton of manual digitopodium relationship: proximally_connected_to UBERON:0010544 ! metacarpus skeleton [Term] id: UBERON:0010690 name: manual digit 1 epithelium namespace: uberon def: "An epithelium that is part of a manual digit 1." [OBOL:automatic] synonym: "fore limb digit 1 epithelium" EXACT [OBOL:accepted] synonym: "hand digit 1 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "manual digit I epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0000512 xref: EMAPA:17430 is_a: UBERON:0005227 ! manual digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: part_of UBERON:0001463 ! manual digit 1 [Term] id: UBERON:0010693 name: pedal digit 1 epithelium namespace: uberon def: "An epithelium that is part of a pedal digit 1." [OBOL:automatic] synonym: "foot digit 1 epithelium" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit 1 epithelium" EXACT [OBOL:accepted] synonym: "pedal digit I epithelium" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: EHDAA2:0002038 xref: EMAPA:17461 is_a: UBERON:0005226 ! pedal digit epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: part_of UBERON:0003631 ! pedal digit 1 [Term] id: UBERON:0010695 name: mesenchyme of tarsal region namespace: uberon def: "Mesenchyme of the carpal region that contributes to the tarsal skeleton." [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:18502 is_a: UBERON:0003860 ! hindlimb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0004454 ! tarsal region relationship: part_of UBERON:0004454 ! tarsal region [Term] id: UBERON:0010696 name: skeleton of pedal acropodium namespace: uberon def: "The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the pedal autopodium - i.e. the bones of the foot or their cartilaginous precursors[cjm]." [https://orcid.org/0000-0002-6601-2165] synonym: "all phalanges in hindlimb autopod" EXACT [] synonym: "foot digit skeleton" EXACT [] synonym: "hind acropodium skeleton" EXACT [] synonym: "pedal phalanges" EXACT [VSAO:0005030, VSAO:NI] synonym: "phalanges of foot" EXACT [FMA:78512] synonym: "phalanges of pes" EXACT [] synonym: "posterior acropodium" RELATED [VSAO:0005030, VSAO:NI] synonym: "posterior acropodium skeleton" EXACT [] synonym: "set of pedal phalanges" EXACT [] synonym: "set of phalanges of foot" EXACT [FMA:78512] synonym: "set of phalanges of pes" EXACT [] xref: FMA:78512 xref: VSAO:0005030 xref: Wikipedia:Phalanges_of_the_foot is_a: UBERON:0010543 ! acropodial skeleton intersection_of: UBERON:0010543 ! acropodial skeleton intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0012152 {source="PHENOSCAPE:ni"} ! skeleton of pedal digitopodium relationship: proximally_connected_to UBERON:0010545 ! metatarsus skeleton [Term] id: UBERON:0010697 name: pedal digit metatarsal cartilage element namespace: uberon synonym: "foot digit metatarsal cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "hind limb digit metatarsal cartilage condensation" EXACT [OBOL:accepted] synonym: "metatarsal cartilage condensation" RELATED [EMAPA:32951] xref: EMAPA:32951 is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element is_a: UBERON:0035129 ! pes cartilage element intersection_of: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation property_value: editor_note "EMAPA represents the specific child classes as being part of the digit mesenchyme - we follow this although for the fully formed structure we represent the metatarsals as adjoining rather than being part of the digit skeleton" xsd:string [Term] id: UBERON:0010698 name: manual digit metacarpus pre-cartilage condensation namespace: uberon synonym: "fore limb digit metacarpus pre-cartilage condensation" EXACT [OBOL:accepted] synonym: "hand digit metacarpus pre-cartilage condensation" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "metacarpal bone pre-cartilage condensation" EXACT [VHOG:0000953] synonym: "metacarpal pre-cartilage condensation" EXACT [] synonym: "metacarpus pre-cartilage condensation" EXACT [VHOG:0000953] xref: EMAPA:32850 xref: VHOG:0000953 is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010699 name: manual digit metacarpus cartilage element namespace: uberon synonym: "finger metacarpus cartilage element" EXACT [] synonym: "fore limb digit metacarpus cartilage element" EXACT [OBOL:accepted] synonym: "hand digit metacarpus cartilage element" NARROW SENSU [NCBITaxon:9606, OBOL:accepted] synonym: "metacarpal cartilage condensation" RELATED [EMAPA:32849] synonym: "metacarpal cartilage element" EXACT [] synonym: "metacarpus cartilage element" EXACT [] xref: EMAPA:32849 is_a: UBERON:0015042 ! manual digit metacarpus endochondral element is_a: UBERON:0035128 ! manus cartilage element intersection_of: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation [Term] id: UBERON:0010700 name: phalanx pre-cartilage condensation namespace: uberon xref: EMAPA:32720 is_a: UBERON:0010882 ! limb bone pre-cartilage condensation is_a: UBERON:0015023 ! phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: part_of UBERON:0010702 {source="EMAPA"} ! digit mesenchyme [Term] id: UBERON:0010701 name: phalanx cartilage element namespace: uberon synonym: "phalanx cartilage condensation" EXACT [EMAPA:32721] xref: EMAPA:32721 is_a: UBERON:0015023 ! phalanx endochondral element is_a: UBERON:0015064 ! autopod cartilage intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010700 ! phalanx pre-cartilage condensation [Term] id: UBERON:0010702 name: digit mesenchyme namespace: uberon def: "Mesenchyme of the digit region." [http://orcid.org/0000-0002-6601-2165] synonym: "digital ray" RELATED [NCIT:C34141] xref: EMAPA:32719 xref: NCIT:C34141 xref: UMLS:C1511959 is_a: UBERON:0009749 ! limb mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0002544 ! digit relationship: part_of UBERON:0002544 ! digit [Term] id: UBERON:0010703 name: forelimb zeugopod skeleton namespace: uberon def: "The collection of all skeletal elements in an forelimb zeugopod region." [https://orcid.org/0000-0002-6601-2165] synonym: "antebrachial skeleton" EXACT [] synonym: "antebrachium skeleton" EXACT [PHENOSCAPE:ni] synonym: "anterior zeugopodium" RELATED [VSAO:0005011, VSAO:NI] synonym: "anterior zeugopodium skeleton" EXACT [VSAO:0005011, VSAO:NI] synonym: "fore epipodium" RELATED [AAO:0000200] synonym: "fore epipodium skeleton" EXACT [] synonym: "forearm skeleton" EXACT [FMA:71199] synonym: "forelimb epipodium" RELATED [VSAO:0005011, VSAO:NI] synonym: "forelimb epipodium skeleton" RELATED [] synonym: "mesomere 2 of pectoral appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "radius and ulna" RELATED [] synonym: "skeleton of forearm" EXACT HUMAN_PREFERRED [FMA:71199] synonym: "wing zeugopod skeleton" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: AAO:0000200 xref: FMA:71199 xref: VSAO:0005011 is_a: UBERON:0011584 ! zeugopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002386 ! forelimb zeugopod disjoint_from: UBERON:0010720 {source="lexical"} ! hindlimb zeugopod skeleton relationship: part_of UBERON:0001440 ! forelimb skeleton relationship: part_of UBERON:0002386 ! forelimb zeugopod relationship: skeleton_of UBERON:0002386 ! forelimb zeugopod property_value: editor_note "adding proxinally_connected_to humerus causes inconsistencies - requires investigation" xsd:string property_value: UBPROP:0000001 "Segment of the forearm corresponding to the radius and ulna.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000200", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0010707 name: appendage girdle complex namespace: uberon def: "An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc)." [https://github.com/obophenotype/uberon/wiki/Appendages-and-the-appendicular-skeleton, https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "appendage complex" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "appendage-girdle complex" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "appendage/girdle complex" EXACT [VSAO:0000214] synonym: "girdle plus limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "limb" RELATED INCONSISTENT [FMA:7182] xref: EMAPA:37858 {source="MA:th"} xref: FMA:7182 xref: VSAO:0000214 is_a: UBERON:0000475 ! organism subdivision is_a: UBERON:0015212 ! lateral structure relationship: dc-contributor https://orcid.org/0000-0001-9114-8737 relationship: functionally_related_to GO:0040011 ! locomotion relationship: in_lateral_side_of UBERON:0000468 ! multicellular organism relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: editor_note "It is still called a complex when one of the two parts is missing (?) There are fossil fishes with only an outgrowth (no record of a girdle), including thelodonts (which have a suprabranchial fin) as well as some anaspids which have a distinctive 'paired fin' (with differing published assertions on whether it's homologous to a pec fin or pelvic fin or both or neither). There are many fishes and other vertebrates with only a girdle and no outgrowth.[VSAO]" xsd:string property_value: UBPROP:0000001 "Anatomical group that consists of the soft and skeletal tissues of the appendicular region of the body and the appendage proper.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000214", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"} property_value: UBPROP:0000005 "It is still called a complex when one of the two parts is missing (?) There are fossil fishes with only an outgrowth (no record of a girdle), including thelodonts (which have a suprabranchial fin) as well as some anaspids which have a distinctive 'paired fin' (with differing published assertions on whether it's homologous to a pec fin or pelvic fin or both or neither). There are many fishes and other vertebrates with only a girdle and no outgrowth.[VSAO]" xsd:string {date_retrieved="2012-09-06", external_class="VSAO:0000214", ontology="VSAO", source="Curator"} property_value: UBPROP:0000012 "note that the FMA uses the term 'limb' to refer to the entire appendage complex (free limb plus girdle region)" xsd:string {external_ontology="FMA"} creation_date: 2012-04-23T10:46:51Z [Term] id: UBERON:0010708 name: pectoral complex namespace: uberon def: "Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle." [VSAO:0000213] subset: pheno_slim synonym: "pectoral appendage/girdle complex" EXACT [VSAO:0000213] synonym: "pectoral girdle plus anterior limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pectoral girdle plus pectoral limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "upper limb" RELATED INCONSISTENT [FMA:7183] synonym: "upper limb and pectoral girdle" RELATED HUMAN_PREFERRED [https://orcid.org/0000-0002-6601-2165] synonym: "upper limb and shoulder" RELATED [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37860 {source="MA:th"} xref: FMA:7183 xref: SCTID:110716002 xref: VSAO:0000213 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010707 ! appendage girdle complex intersection_of: UBERON:0010707 ! appendage girdle complex intersection_of: has_part UBERON:0001421 ! pectoral girdle region relationship: has_part UBERON:0001421 ! pectoral girdle region relationship: has_skeleton UBERON:0012475 ! skeleton of pectoral complex relationship: part_of UBERON:0000153 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! anterior region of body property_value: UBPROP:0000001 "Appendage girdle complex that when present, encompasses the pectoral appendage and half of the pectoral girdle.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000213", ontology="VSAO", source="VSAO:MAH"} property_value: UBPROP:0000012 "note that the FMA uses the terms 'upper limb' and 'lower limb' to refer to the entire appendage complex (free limb plus girdle region)" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0010709 name: pelvic complex namespace: uberon def: "Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle." [VSAO:0000215] subset: pheno_slim synonym: "lower limb" RELATED INCONSISTENT [FMA:7184] synonym: "lower limb and pelvic girdle" RELATED HUMAN_PREFERRED [https://orcid.org/0000-0002-6601-2165] synonym: "lower limb and pelvis" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "pelvic appendage/girdle complex" EXACT [VSAO:0000215] synonym: "pelvic girdle plus pelvic limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "pelvic girdle plus posterior limb or fin" EXACT [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37863 {source="MA:th"} xref: FMA:7184 xref: SCTID:416631005 xref: VSAO:0000215 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010707 ! appendage girdle complex intersection_of: UBERON:0010707 ! appendage girdle complex intersection_of: has_part UBERON:0001271 ! pelvic girdle region relationship: has_part UBERON:0001271 ! pelvic girdle region relationship: has_skeleton UBERON:0012476 ! skeleton of pelvic complex relationship: part_of UBERON:0000154 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! posterior region of body property_value: RO:0002171 UBERON:0010708 property_value: UBPROP:0000001 "Appendage girdle complex that when present, encompasses the pelvic appendage and the pelvic girdle.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000215", ontology="VSAO", source="VSAO:MAH"} property_value: UBPROP:0000012 "note that the FMA uses the terms 'upper limb' and 'lower limb' to refer to the entire appendage complex (free limb plus girdle region). Note the MA class 'hindlimb' may also belong here" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0010712 name: limb skeleton subdivision namespace: uberon def: "Skeletal subdivision that is a segment of the limb skeleton." [VSAO:0005018, VSAO:NI] xref: VSAO:0005018 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002091 {source="VSAO"} ! appendicular skeleton relationship: part_of UBERON:0002101 ! limb property_value: editor_note "note the distinction between this and skeleton of limb" xsd:string [Term] id: UBERON:0010714 name: iliac cartilage element namespace: uberon def: "An iliac endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "iliac cartilage condensation" RELATED [EMAPA:18347] xref: EHDAA2:0000808 xref: EMAPA:18347 xref: VHOG:0001126 is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0015054 ! iliac endochondral element intersection_of: UBERON:0015054 ! iliac endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006247 {source="EHDAA2"} ! iliac pre-cartilage condensation [Term] id: UBERON:0010718 name: pubic cartilage element namespace: uberon def: "A pubic endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "pubic cartilage condensation" RELATED [EMAPA:26928] xref: EHDAA2:0001573 xref: EMAPA:26928 is_a: UBERON:0005863 {source="EHDAA2"} ! cartilaginous condensation is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0015055 ! pubic endochondral element intersection_of: UBERON:0015055 ! pubic endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006285 {source="EHDAA2"} ! pubic pre-cartilage condensation [Term] id: UBERON:0010719 name: girdle skeleton namespace: uberon def: "The subdivision of the skeleton of either the pectoral or pelvic girdle." [https://orcid.org/0000-0002-6601-2165] synonym: "skeleton of girdle" EXACT [] xref: AAO:0010686 xref: VSAO:0000302 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0007823 ! appendage girdle region relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002091 ! appendicular skeleton relationship: part_of UBERON:0007823 ! appendage girdle region relationship: proximally_connected_to UBERON:0002090 ! postcranial axial skeleton relationship: skeleton_of UBERON:0007823 ! appendage girdle region property_value: UBPROP:0000001 "Skeletal subdivision that is part of the appendage girdle region.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000302", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"} property_value: UBPROP:0000002 "relationship type change: subclass skeletal subdivision (VSAO:0000042) CHANGED TO: part_of subdivision of skeleton (UBERON:0010912)[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000302", ontology="VSAO"} property_value: UBPROP:0000002 "relationship type change: subclass skeletal subdivision (VSAO:0000042) CHANGED TO: proximally_connected_to subdivision of skeleton (UBERON:0010912)[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000302", ontology="VSAO"} [Term] id: UBERON:0010720 name: hindlimb zeugopod skeleton namespace: uberon def: "Subdivision of skeleton consisting of all skeletal elements in an hindlimb zeugopod region. Typically consists of the tibia and the fibula." [https://orcid.org/0000-0002-6601-2165] synonym: "crural skeleton" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "crus skeleton" EXACT [PHENOSCAPE:ni] synonym: "hind epipodium" RELATED [AAO:0000216] synonym: "hindlimb epipodium" RELATED [VSAO:0005014, VSAO:NI] synonym: "hindlimb zygopod skeleton" EXACT [] synonym: "mesomere 2 of pelvic appendage" RELATED HOMOLOGY [ISBN:0226313409] synonym: "posterior zeugopodium" RELATED INCONSISTENT [VSAO:0005014] synonym: "posterior zeugopodium skeleton" EXACT [] synonym: "skeleton cruris" EXACT LATIN [NominaAnatomicaVeterinaria:2005] xref: AAO:0000216 xref: VSAO:0005014 is_a: UBERON:0011584 ! zeugopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0003823 ! hindlimb zeugopod relationship: part_of UBERON:0003823 ! hindlimb zeugopod relationship: proximally_connected_to UBERON:0000981 ! femur relationship: skeleton_of UBERON:0003823 ! hindlimb zeugopod property_value: UBPROP:0000001 "Segment of the leg corresponding to the tibia and fibula.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000216", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0010721 name: distal tarsal bone namespace: uberon def: "There are three cuneiform bones in the human foot: the medial cuneiform the intermediate cuneiform also known as the middle the lateral cuneiform. They are located between the navicular bone and the first, second and third metatarsal bones and are medial to the cuboid bone[WP, unvetted, human specific]." [Wikipedia:Cuneiform_(anatomy)] synonym: "cuneiform" RELATED [] synonym: "cuneiform bone" EXACT [FMA:24517] synonym: "distal tarsal" EXACT [AAO:0000914] synonym: "distal tarsal bone" EXACT [] synonym: "os cuneiform" EXACT [] synonym: "os cuneiforme" EXACT [] xref: AAO:0000914 xref: FMA:24517 xref: NCIT:C32416 xref: SCTID:182102002 xref: UMLS:C1511560 {source="ncithesaurus:Cuneiform_Bone_of_the_Foot"} xref: Wikipedia:Cuneiform_(anatomy) is_a: UBERON:0001447 ! tarsal bone is_a: UBERON:0015099 ! distal tarsal endochondral element is_a: UBERON:0018102 ! distal mesopodial bone intersection_of: UBERON:0015099 ! distal tarsal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015100 ! distal tarsal cartilage relationship: distally_connected_to UBERON:0001448 ! metatarsal bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/9e/Gray268.png" xsd:anyURI property_value: UBPROP:0000001 "Series of elements that articulate with the metatarsals.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000914", ontology="AAO", source="AAO:LAP"} [Term] id: UBERON:0010724 name: lateral tubercle of talus namespace: uberon def: "An accessory bone tubercle which if present lies posterior to the talus." [Wikipedia:Os_trigonum] synonym: "accessory talus" EXACT [Wikipedia:Os_trigonum] synonym: "os trigonum" EXACT LATIN [FMA:TA] synonym: "os trigonum of talus" EXACT [FMA:33655] synonym: "tuberculum laterale (talus)" EXACT [FMA:33655] xref: FMA:33655 xref: SCTID:87573005 xref: Wikipedia:Os_trigonum is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005813 {source="FMA"} ! tubercle relationship: part_of UBERON:0002387 ! pes [Term] id: UBERON:0010740 name: bone of appendage girdle complex namespace: uberon def: "A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle)." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: pheno_slim synonym: "bone of extended limb/fin region" RELATED [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "limb bone" RELATED [MA:0000688, UBERONREF:0000003] xref: EMAPA:35494 xref: MA:0000688 is_a: UBERON:0001474 ! bone element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0010707 ! appendage girdle complex relationship: contributes_to_morphology_of UBERON:0002091 ! appendicular skeleton relationship: part_of UBERON:0002091 {notes="UBERONREF:0000003"} ! appendicular skeleton relationship: part_of UBERON:0010707 ! appendage girdle complex [Term] id: UBERON:0010741 name: bone of pectoral complex namespace: uberon def: "A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: pheno_slim synonym: "bone of forelimb or pectoral fin or pectoral girdle" RELATED [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] synonym: "forelimb bone" RELATED [MA:0000612, UBERONREF:0000003] synonym: "wing bone" NARROW SENSU [UBERONREF:0000003] xref: EMAPA:32623 xref: EMAPA:35933 xref: MA:0000612 is_a: UBERON:0010740 ! bone of appendage girdle complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: part_of UBERON:0010708 ! pectoral complex property_value: editor_note "considering adding pectoral and pelvic complex skeleton classes" xsd:string property_value: UBPROP:0000012 "note that the MA class includes girdle parts so it belongs here;" xsd:string {external_ontology="MA"} [Term] id: UBERON:0010742 name: bone of pelvic complex namespace: uberon def: "A bone that is part of a pelvic complex. Examples: pubis, ischium, fot phalanx, any tarsal bone, any bone of the pelvic fin or girdle." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: pheno_slim synonym: "hindlimb bone" RELATED [MA:0000660, UBERONREF:0000003] xref: EMAPA:32633 xref: EMAPA:35934 xref: MA:0000660 is_a: UBERON:0010740 {source="MA"} ! bone of appendage girdle complex intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: part_of UBERON:0010709 ! pelvic complex property_value: UBPROP:0000012 "the MA class called 'hindlimb bone' belongs here, as it includes bones in the pelvic girdle" xsd:string {external_ontology="MA"} [Term] id: UBERON:0010743 name: meningeal cluster namespace: uberon def: "The collection of all meningeal layers that line a central nervous system." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "cerebral meninges" EXACT [] synonym: "cluster of meninges" EXACT [FMA:231572] synonym: "meninges" EXACT [FMA:231572] xref: EHDAA2:0004661 xref: EMAPA:32660 xref: FMA:231572 xref: NCIT:C12349 xref: neuronames:1465 xref: SCTID:362879001 xref: UMLS:C0228116 xref: Wikipedia:Meninges is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0034925 ! anatomical collection intersection_of: UBERON:0034925 ! anatomical collection intersection_of: bounding_layer_of UBERON:0001017 ! central nervous system intersection_of: has_member UBERON:0002360 ! meninx relationship: bounding_layer_of UBERON:0001017 ! central nervous system relationship: has_member UBERON:0002360 ! meninx relationship: part_of UBERON:0001017 ! central nervous system property_value: UBPROP:0000007 "meningeal" xsd:string property_value: UBPROP:0000008 "In some primitive organisms, the meningeal cluster includes only the primitive meninx" xsd:string [Term] id: UBERON:0010744 name: sacral vertebra pre-cartilage condensation namespace: uberon def: "A sacral vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] synonym: "sacral vertebral pre-cartilage condensation group" EXACT [EHDAA2:0001774] xref: EHDAA2:0001774 xref: EMAPA:17677 is_a: UBERON:0011095 ! vertebra pre-cartilage condensation is_a: UBERON:0015010 ! sacral vertebra endochondral element intersection_of: UBERON:0015010 ! sacral vertebra endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010745 name: sacral vertebra cartilage element namespace: uberon def: "A sacral vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "sacral vertebral cartilage condensation" EXACT [] synonym: "sacral vertebral cartilage condensation group" EXACT [EHDAA2:0001773] xref: EHDAA2:0001773 xref: EMAPA:18009 is_a: UBERON:0011094 ! vertebra cartilage element is_a: UBERON:0015010 ! sacral vertebra endochondral element is_a: UBERON:2001457 ! postcranial axial cartilage intersection_of: UBERON:0015010 ! sacral vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010744 {source="EHDAA2"} ! sacral vertebra pre-cartilage condensation [Term] id: UBERON:0010758 name: subdivision of organism along appendicular axis namespace: uberon def: "A major subdivision of an organism that divides an organism along an axis perpedicular to the main body anterior-posterior axis. In vertebrates, this is typically a fin or limb segment. In insects, this includes segments of appendages such as antennae, as well as segments of the insect leg." [https://orcid.org/0000-0002-6601-2165] subset: upper_level synonym: "appendage segment" EXACT [FBbt:00007018] synonym: "appendicular segment" EXACT [] xref: FBbt:00007018 is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0000026 ! appendage [Term] id: UBERON:0010801 name: calcaneum pre-cartilage condensation namespace: uberon def: "A calcaneum endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] synonym: "calcaneous pre-cartilage condensation" EXACT [] xref: EMAPA:17736 is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0010695 ! mesenchyme of tarsal region is_a: UBERON:0010886 ! hindlimb pre-cartilage condensation is_a: UBERON:0015014 ! calcaneum endochondral element intersection_of: UBERON:0015014 ! calcaneum endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010842 name: calcaneum cartilage element namespace: uberon def: "A calcaneum endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "calcaneous cartilage element" EXACT [] xref: EMAPA:18143 is_a: UBERON:0005863 ! cartilaginous condensation is_a: UBERON:0010695 ! mesenchyme of tarsal region is_a: UBERON:0015014 ! calcaneum endochondral element is_a: UBERON:0035129 ! pes cartilage element intersection_of: UBERON:0015014 ! calcaneum endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010801 ! calcaneum pre-cartilage condensation [Term] id: UBERON:0010843 name: clavicle cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a clavicle." [OBOL:automatic] xref: EMAPA:18342 is_a: UBERON:0005863 ! cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: has_potential_to_develop_into UBERON:0001105 ! clavicle bone relationship: develops_from UBERON:0010844 ! clavicle pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0001105 ! clavicle bone relationship: part_of UBERON:0007831 ! pectoral girdle skeleton property_value: UBPROP:0000008 "In most birds and mammals the clavicles are the only dermal elements in the trunk, and is the only membrane bone associated with the pectoral girdle in these taxa. However, there can be secondary cartilage, or subsequent endochondral ossification, or fusion with endochondral elements. In rodents, the lateral ends of the clavicle are endochondral but the main portion is dermal." xsd:string {source="ISBN:978-0-12-319060-4"} [Term] id: UBERON:0010844 name: clavicle pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a clavicle." [OBOL:automatic] xref: EMAPA:18026 is_a: UBERON:0005866 ! pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0001105 ! clavicle bone relationship: has_potential_to_develop_into UBERON:0001105 ! clavicle bone relationship: part_of UBERON:0007831 ! pectoral girdle skeleton property_value: UBPROP:0000008 "In most birds and mammals the clavicles are the only dermal elements in the trunk, and is the only membrane bone associated with the pectoral girdle in these taxa. However, there can be secondary cartilage, or subsequent endochondral ossification, or fusion with endochondral elements. In rodents, the lateral ends of the clavicle are endochondral but the main portion is dermal." xsd:string {source="ISBN:978-0-12-319060-4"} [Term] id: UBERON:0010846 name: radius pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a radius bone." [OBOL:automatic] xref: EHDAA2:0001586 is_a: UBERON:0003327 ! mesenchyme of forearm is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0015001 ! radius endochondral element intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0001423 ! radius bone relationship: develops_from UBERON:0006287 {source="EHDAA2"} ! radius-ulna pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0001423 ! radius bone relationship: part_of UBERON:0003327 {source="EHDAA2"} ! mesenchyme of forearm property_value: editor_note "still to decide whether this is a distinct pre-cartilage condensation" xsd:string [Term] id: UBERON:0010847 name: ulna pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a ulna." [OBOL:automatic] xref: EHDAA2:0002100 xref: EHDAA:6226 is_a: UBERON:0003327 ! mesenchyme of forearm is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0015003 ! ulna endochondral element intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0001424 ! ulna relationship: develops_from UBERON:0006287 {source="EHDAA2"} ! radius-ulna pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0001424 ! ulna relationship: part_of UBERON:0003327 {source="EHDAA2"} ! mesenchyme of forearm [Term] id: UBERON:0010848 name: radius-ulna cartilage element namespace: uberon def: "A radius-ulna endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "radio-ulna cartilage condensation" EXACT [EMAPA:17711] xref: EMAPA:17711 is_a: UBERON:0003327 ! mesenchyme of forearm is_a: UBERON:0005863 ! cartilaginous condensation is_a: UBERON:0010883 ! forelimb cartilage element is_a: UBERON:0015002 ! radius-ulna endochondral element intersection_of: UBERON:0015002 ! radius-ulna endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0006287 ! radius-ulna pre-cartilage condensation relationship: part_of UBERON:0003327 {source="EMAPA"} ! mesenchyme of forearm property_value: UBPROP:0000012 "note that this is not represented as a single unit in EHDAA2" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0010849 name: tibia cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a tibia." [OBOL:automatic] xref: EMAPA:18155 is_a: UBERON:0010885 ! hindlimb cartilage element is_a: UBERON:0015004 ! tibia endochondral element intersection_of: UBERON:0015004 ! tibia endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010850 ! tibia pre-cartilage condensation relationship: part_of UBERON:0005259 {source="EMAPA"} ! lower leg mesenchyme [Term] id: UBERON:0010850 name: tibia pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a tibia." [OBOL:automatic] xref: EHDAA2:0002036 is_a: UBERON:0005259 ! lower leg mesenchyme is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0015004 ! tibia endochondral element intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0000979 ! tibia relationship: has_potential_to_develop_into UBERON:0000979 ! tibia relationship: part_of UBERON:0005259 {source="EHDAA2"} ! lower leg mesenchyme [Term] id: UBERON:0010851 name: fibula cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a fibula." [OBOL:automatic] synonym: "fibulal cartilage condensation" EXACT [EMAPA:18154] synonym: "fibular cartilage condensation" EXACT [EMAPA:18154] synonym: "fibulra cartilage condensation" RELATED [EMAPA:18154] xref: EMAPA:18154 is_a: UBERON:0010885 ! hindlimb cartilage element is_a: UBERON:0015013 ! fibula endochondral element intersection_of: UBERON:0015013 ! fibula endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010852 ! fibula pre-cartilage condensation relationship: part_of UBERON:0005259 {source="EMAPA"} ! lower leg mesenchyme [Term] id: UBERON:0010852 name: fibula pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a fibula." [OBOL:automatic] synonym: "fibulal pre-cartilage condensation" EXACT [] synonym: "fibular pre-cartilage condensation" EXACT [] xref: EHDAA2:0000509 xref: EHDAA:6196 is_a: UBERON:0005259 ! lower leg mesenchyme is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0015013 ! fibula endochondral element intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0001446 ! fibula relationship: has_potential_to_develop_into UBERON:0001446 ! fibula relationship: part_of UBERON:0005259 {source="EHDAA2"} ! lower leg mesenchyme [Term] id: UBERON:0010853 name: capitulum of humerus namespace: uberon def: "A smooth, rounded eminence on the lateral portion of the articular surface of the humerus. It articulates with the cupshaped depression on the head of the radius, and is limited to the front and lower part of the bone." [Wikipedia:Capitulum_of_the_humerus] subset: human_reference_atlas synonym: "capitellum" RELATED [Wikipedia:Capitulum_of_the_humerus] synonym: "capitulum humeri" RELATED LATIN [Wikipedia:Capitulum_of_the_humerus] synonym: "capitulum of humerus" RELATED [Wikipedia:Capitulum_of_the_humerus] synonym: "dorsal condyle of the humerus" RELATED SENSU [Wikipedia:Capitulum_of_the_humerus] synonym: "humeral capitulum" EXACT [FMA:23373] xref: FMA:23373 xref: SCTID:282816008 xref: Wikipedia:Capitulum_of_the_humerus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: part_of UBERON:0009988 {source="FMA"} ! condyle of humerus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/b9/Capitulumhumeri.PNG" xsd:anyURI property_value: editor_note "TODO - check AAO." xsd:string {source="WP"} property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In birds, where forelimb anatomy has adaptation for flight, its functional if not ontogenetic equivalent is the dorsal condyle of the humerus" xsd:string property_value: UBPROP:0000008 "The Capitulum humeri is present in Carnivora, more distinctly in the cat than in the dog. The Fossa coronoidea, present in the cat is medial to the Fossa radialis and accommodates the Processus coronoideus medialis ulnae when the elbow is flexed. A Foramen supratrochleare occurs in carnivora and occasionally in pig.[NOMINA ANATOMICA VETERINARIA (2005)]" xsd:string [Term] id: UBERON:0010881 name: limb cartilage element namespace: uberon def: "A skeletal element that is part of a limb and composed of cartilage tissue." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0015061 ! limb endochondral element intersection_of: UBERON:0015061 ! limb endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010882 ! limb bone pre-cartilage condensation [Term] id: UBERON:0010882 name: limb bone pre-cartilage condensation namespace: uberon def: "A skeletal element that is part of a limb and composed of pre-cartilage tissue." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0015061 ! limb endochondral element intersection_of: UBERON:0015061 ! limb endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010883 name: forelimb cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a forelimb bone." [OBOL:automatic] subset: grouping_class synonym: "forelimb wing cartilaginous condensation" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] synonym: "wing cartilaginous condensation" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:32626 is_a: UBERON:0010881 ! limb cartilage element is_a: UBERON:0015021 ! forelimb endochondral element intersection_of: UBERON:0015021 ! forelimb endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010884 ! forelimb bone pre-cartilage condensation [Term] id: UBERON:0010884 name: forelimb bone pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a forelimb bone." [OBOL:automatic] subset: grouping_class synonym: "wing bone pre-cartilage condensation" NARROW SENSU [NCBITaxon:8782, OBOL:automatic] xref: EMAPA:32625 is_a: UBERON:0010882 ! limb bone pre-cartilage condensation is_a: UBERON:0015021 ! forelimb endochondral element intersection_of: UBERON:0015021 ! forelimb endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010885 name: hindlimb cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a hindlimb bone." [OBOL:automatic] synonym: "hindlimb cartilage condensation" EXACT [EMAPA:32632] xref: EMAPA:32632 is_a: UBERON:0010881 ! limb cartilage element is_a: UBERON:0015022 ! hindlimb endochondral element intersection_of: UBERON:0015022 ! hindlimb endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0010886 ! hindlimb pre-cartilage condensation [Term] id: UBERON:0010886 name: hindlimb pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a hindlimb bone." [OBOL:automatic] synonym: "hindlimb pre-cartilage condensation" EXACT [EMAPA:32638] xref: EMAPA:32638 is_a: UBERON:0010882 ! limb bone pre-cartilage condensation is_a: UBERON:0015022 ! hindlimb endochondral element intersection_of: UBERON:0015022 ! hindlimb endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0010887 name: tragus namespace: uberon def: "A small pointed eminence of the external ear, situated in front of the concha, and projecting backward over the meatus." [Wikipedia:Tragus_(ear)] subset: pheno_slim synonym: "tragal part of pinna" EXACT [FMA:60998] xref: FMA:60998 xref: NCIT:C33801 xref: SCTID:362541003 xref: UMLS:C0229312 {source="ncithesaurus:Tragus"} xref: Wikipedia:Tragus_(ear) is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001444 ! subdivision of head relationship: develops_from UBERON:0016611 {source="Wikipedia-uncited"} ! auditory hillocks, pharyngeal arch 1 derived relationship: part_of UBERON:0001757 {source="FMA"} ! pinna property_value: UBPROP:0000008 "The tragus is generally believed to play a role in vertical sound localization in bats" xsd:string [Term] id: UBERON:0010890 name: pelvic complex muscle namespace: uberon def: "Muscles of the pelvic girdle, hindlimb or pelvic fin." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "lower limb muscle" RELATED INCONSISTENT [FMA:9622] synonym: "muscle of lower limb" RELATED INCONSISTENT [FMA:9622] synonym: "muscle of pelvic girdle and leg" RELATED [] synonym: "pelvic girdle and hind limb muscles" EXACT [AAO:0000218] synonym: "pelvic girdle or hind limb muscle" NARROW [https://orcid.org/0000-0002-6601-2165] synonym: "pelvic girdle or posterior limb muscle" NARROW [https://orcid.org/0000-0002-6601-2165] xref: AAO:0000218 xref: EMAPA:32634 xref: FMA:9622 xref: MA:0000663 is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: part_of UBERON:0014792 {source="prolog"} ! musculature of pelvic complex property_value: UBPROP:0000001 "Muscles of the pelvic girdle, thigh, leg (crus), and foot (pes).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000218", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0010891 name: pectoral complex muscle namespace: uberon def: "A muscle of a pectoral girdle, pectoral fin or anterior limb." [https://orcid.org/0000-0002-6601-2165] synonym: "muscle of pectoral girdle and limb" RELATED [] synonym: "muscle of pectoral girdle and wing" NARROW SENSU [NCBITaxon:8782] synonym: "muscle of upper limb" NARROW INCONSISTENT [FMA:9621] synonym: "pectoral girdle and fore limb muscles" EXACT [AAO:0010687] synonym: "upper limb muscle" NARROW INCONSISTENT [FMA:9621] xref: AAO:0010687 xref: EMAPA:32624 xref: FMA:9621 xref: MA:0000615 is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: part_of UBERON:0014793 {source="prolog"} ! musculature of pectoral complex property_value: editor_note "the MA class belongs here, based on its current child classes" xsd:string property_value: UBPROP:0000001 "Muscles of the pectoral girdle, arm, forearm, and hand (brachium, antebrachium, manus respectively).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010687", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0010893 name: median external naris namespace: uberon alt_id: UBERON:0012123 def: "Am unpaired external naris that lies in the midline of the head." [OBOL:automatic] subset: cyclostome_subset synonym: "median anterior naris" EXACT [] synonym: "median nostril" EXACT [] synonym: "nasohypophysial opening" EXACT [http://tolweb.org/Hyperoartia] is_a: UBERON:0005928 ! external naris intersection_of: UBERON:0005928 ! external naris intersection_of: intersects_midsagittal_plane_of UBERON:0000033 ! head relationship: intersects_midsagittal_plane_of UBERON:0000033 ! head property_value: RO:0002161 NCBITaxon:314146 property_value: RO:0002175 NCBITaxon:7762 [Term] id: UBERON:0010894 name: keratinous tooth namespace: uberon comment: The hagfish's jawless mouth contains two parallel rows of pointed keratinous teeth subset: cyclostome_subset synonym: "horny denticle" EXACT [http://tolweb.org/Hyperoartia] is_a: UBERON:0003913 ! tooth-like structure intersection_of: UBERON:0003913 ! tooth-like structure intersection_of: composed_primarily_of GO:0045095 ! keratin filament relationship: composed_primarily_of GO:0045095 ! keratin filament relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: RO:0002175 NCBITaxon:117569 property_value: RO:0002175 NCBITaxon:7762 [Term] id: UBERON:0010899 name: synchronous hermaphroditic organism namespace: uberon def: "Hermaphroditic organism that produces both male and female gametes at the same time." [CARO:0000046] synonym: "serially hermaphroditic organism" RELATED [CARO:0000046] synonym: "simultaneous hermaphroditic organism" RELATED [https://orcid.org/0000-0002-6601-2165] xref: AAO:0010046 xref: BILA:0000046 xref: CARO:0000046 xref: HAO:0000046 xref: TADS:0000609 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0007197 {source="CARO"} ! hermaphroditic organism intersection_of: UBERON:0000468 ! multicellular organism intersection_of: has_part UBERON:0000473 ! testis intersection_of: has_part UBERON:0000992 ! ovary relationship: has_part UBERON:0000473 ! testis relationship: has_part UBERON:0000992 ! ovary [Term] id: UBERON:0010905 name: clavicle bone primordium namespace: uberon def: "A primordium that develops into a clavicle bone." [https://github.com/obophenotype/uberon/issues/327] comment: lateral part derives from a fish dermal bone while the medial part comes from a spur off the manubrium endochondral bone[JB] synonym: "clavicle primordium" EXACT [] xref: EHDAA2:0000254 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0001105 ! clavicle bone relationship: develops_from UBERON:0006210 {source="EHDAA2"} ! body-wall mesenchyme relationship: has_developmental_contribution_from UBERON:0002342 {editor="mah", notes="shown in mouse", source="PMC1352163"} ! neural crest relationship: has_potential_to_develop_into UBERON:0001105 ! clavicle bone relationship: part_of UBERON:0007831 {source="EHDAA2"} ! pectoral girdle skeleton [Term] id: UBERON:0010911 name: ossicle namespace: uberon def: "Skeletal element that is often isolated, small, and variable in composition." [PSPUB:0000169, VSAO:0000132] comment: Ossicles are composed of a combination skeletal tissues, including bone, calcified cartilage, hyaline cartilage, etc, and exhibit variable development across species. Ossicles are not necessarily jointed, and examples include the menisci of synovial joints, 'Panda's thumb' (radial sesamoid), cardiac skeletal elements, sclerotic bones, middle ear ossicles, and sesamoids. subset: human_reference_atlas xref: VSAO:0000132 xref: Wikipedia:Ossicles is_a: UBERON:0004765 {source="VSAO"} ! skeletal element property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0010912 name: subdivision of skeleton namespace: uberon def: "Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints." [https://orcid.org/0000-0002-6601-2165, UBERONREF:0000003] subset: non_informative synonym: "skeletal subdivision" EXACT [VSAO:0000042] synonym: "subdivision of skeleton (in vivo)" RELATED [FMA:23879] xref: FMA:23879 xref: SCTID:129140006 xref: VSAO:0000042 is_a: UBERON:0011216 {source="cjm"} ! organ system subdivision relationship: part_of UBERON:0000075 {source="UBERONREF:0000003"} ! subdivision of skeletal system relationship: part_of UBERON:0004288 {source="VSAO"} ! skeleton property_value: UBPROP:0000001 "Anatomical cluster consisting of the skeletal elements that are part of the skeleton.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000042", notes="incorrect", ontology="VSAO", source="VSAO:curator"} [Term] id: UBERON:0010913 name: vertebral element namespace: uberon alt_id: UBERON:0015005 def: "Skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, https://github.com/obophenotype/uberon/issues/294, VSAO:0000184] synonym: "vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "vertebra endochondral element" NARROW [https://github.com/obophenotype/uberon/issues/82] synonym: "vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "vertebral endochondral element" NARROW [https://github.com/obophenotype/uberon/issues/82] xref: VHOG:0001143 xref: VSAO:0000184 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004765 {source="VSAO", source="https://github.com/obophenotype/uberon/issues/82"} ! skeletal element relationship: develops_from UBERON:0003089 {source="cjm"} ! sclerotome relationship: part_of UBERON:0001130 {source="VSAO"} ! vertebral column property_value: IAO:0000232 "we include a distinct subclass for bony vertebra" xsd:string property_value: UBPROP:0000003 "In contrast to lampreys and jawed vertebrates, hagfishes were thought to lack vertebrae. Now, long overlooked vertebral rudiments have been analysed in hagfish, suggesting that vertebrae existed in the last common ancestor of all vertebrates.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001143", ontology="VHOG", source="DOI:10.1016/j.cub.2011.07.014 Janvier P, Comparative anatomy: all vertebrates do have vertebrae. Current Biology (2011)", source="http://bgee.unil.ch/"} property_value: UBPROP:0000007 "vertebral" xsd:string property_value: UBPROP:0000008 "Typically an endochondral element, in salamanders there is an argument that vertebral development is perichondral and not preformed in cartilage" xsd:string [Term] id: UBERON:0010948 name: cleidooccipital muscle namespace: uberon def: "A muscle organ that attaches_to a clavicle and attaches_to a occipital bone." [OBOL:automatic] comment: Some studies have indicated a supernumerary cleido-occipital muscle more or less separate from the sterno-cleido-mastoid muscle; The frequency of cleido-occipital muscle occurrence has been reported up to 33% synonym: "cleido-occipitalis" EXACT [] synonym: "cleido-occipitalis muscle" EXACT [] synonym: "cleidooccipital" EXACT [MA:0002276] xref: EMAPA:37688 {source="MA:th"} xref: MA:0002276 xref: NCIT:C52895 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000933 ! chordate pharyngeal muscle is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0001105 ! clavicle bone intersection_of: attaches_to UBERON:0001676 ! occipital bone relationship: attaches_to UBERON:0001105 ! clavicle bone relationship: attaches_to UBERON:0001676 ! occipital bone [Term] id: UBERON:0010949 name: sternooccipital muscle namespace: uberon def: "A muscle organ that has_muscle_insertion a occipital bone and has_muscle_origin a sternum." [OBOL:automatic] synonym: "sternooccipital" EXACT [MA:0002385] xref: EMAPA:37702 {source="MA:th"} xref: MA:0002385 xref: NCIT:C53069 xref: UMLS:C1710196 {source="ncithesaurus:Sternooccipital"} is_a: UBERON:0002377 ! muscle of neck is_a: UBERON:0003897 ! axial muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: has_muscle_insertion UBERON:0001676 ! occipital bone intersection_of: has_muscle_origin UBERON:0000975 ! sternum relationship: has_muscle_insertion UBERON:0001676 ! occipital bone relationship: has_muscle_origin UBERON:0000975 ! sternum [Term] id: UBERON:0010955 name: trapezius pre-muscle mass namespace: uberon xref: EHDAA2:0002079 is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation is_a: UBERON:0006904 ! head mesenchyme from mesoderm is_a: UBERON:0010258 ! mesenchyme from rhombencephalic neural crest relationship: develops_from UBERON:0010258 {source="EHDAA2"} ! mesenchyme from rhombencephalic neural crest relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle [Term] id: UBERON:0010959 name: craniocervical muscle namespace: uberon def: "Any muscle organ that is part of either the head or the neck." [http://orcid.org/0000-0002-6601-2165] synonym: "muscle of head and neck" RELATED [] synonym: "muscle of head or neck" EXACT [] xref: NCIT:C32716 xref: UMLS:C0448281 {source="ncithesaurus:Head_and_Neck_Muscle"} is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0008229 {source="prolog"} ! craniocervical region musculature [Term] id: UBERON:0010963 name: trunk and cervical myotome group namespace: uberon comment: isa row in EHDAA2 xref: EHDAA2:0003425 is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0003082 ! myotome relationship: part_of UBERON:0005256 {source="EHDAA2"} ! trunk mesenchyme [Term] id: UBERON:0010982 name: latissimus dorsi pre-muscle mass namespace: uberon xref: EHDAA2:0000933 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle [Term] id: UBERON:0010983 name: levator scapulae pre-muscle mass namespace: uberon xref: EHDAA2:0000993 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0008713 {source="EHDAA2"} ! pectoral girdle and thoracic body wall skeletal muscle [Term] id: UBERON:0010986 name: serratus ventralis pre-muscle mass namespace: uberon synonym: "serratus anterior pre-muscle mass" EXACT [EHDAA2:0001833] xref: EHDAA2:0001833 xref: EHDAA:5992 is_a: UBERON:0005865 {source="EHDAA2"} ! pre-muscle condensation relationship: develops_from UBERON:0010963 {source="EHDAA2"} ! trunk and cervical myotome group relationship: part_of UBERON:0003897 {source="EHDAA2"} ! axial muscle [Term] id: UBERON:0011004 name: pharyngeal arch cartilage namespace: uberon def: "A cartilage element that is part of a splanchnocranium." [OBOL:automatic] subset: efo_slim synonym: "pharyngeal arch cartilages" EXACT PLURAL [ZFA:0001460] synonym: "splanchnocranium cartilage" EXACT [ZFA:0001460] xref: EFO:0003689 xref: TAO:0001460 xref: ZFA:0001460 is_a: UBERON:0003933 {source="ZFA"} ! cranial cartilage intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0008895 ! splanchnocranium relationship: develops_from UBERON:0002539 ! pharyngeal arch relationship: part_of UBERON:0008895 {source="ZFA"} ! splanchnocranium [Term] id: UBERON:0011050 name: thoracic vertebra 8 namespace: uberon def: "The eighth thoracic vertebra counting from the top down. Note that members of this class are not necessarily homologous[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:T8_Vertebra] subset: human_reference_atlas synonym: "eighth dorsal vertebra" EXACT [FMA:9991] synonym: "eighth thoracic vertebra" EXACT [FMA:9991] synonym: "T8 vertebra" EXACT [FMA:9991] xref: EMAPA:19549 xref: FMA:9991 xref: MA:0001445 xref: NCIT:C33730 xref: SCTID:181836007 xref: UMLS:C0459953 {source="ncithesaurus:T8_Vertebra"} is_a: UBERON:0002347 {source="MA"} ! thoracic vertebra relationship: anteriorly_connected_to UBERON:0004632 {source="FMA"} ! thoracic vertebra 7 relationship: part_of RO:0002577 ! system property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0011085 name: palatoquadrate arch namespace: uberon def: "The dorsal portion of the first pharyngeal arch, comprising the upper jaw[ZFIN,VHOG]." [https://github.com/obophenotype/uberon/issues/153, VHOG:0000511] subset: efo_slim synonym: "dorsal mandibular arch" RELATED [VHOG:0000511] synonym: "dorsal pharyngeal arch 1" RELATED [VHOG:0000511] synonym: "dorsal visceral arch 1" EXACT [ZFA:0001272] synonym: "dorsal visceral arch 1" RELATED [VHOG:0000511] synonym: "palatoquadrate arch" RELATED [VHOG:0000511] synonym: "upper jaw" RELATED [VHOG:0000511] synonym: "upper pharyngeal jaw" EXACT [ZFA:0001272] synonym: "upper pharyngeal jaw" RELATED [VHOG:0000511] xref: EFO:0003659 xref: TAO:0001272 xref: VHOG:0000511 xref: ZFA:0001272 is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010912 {source="cjm"} ! subdivision of skeleton relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0003277 ! skeleton of upper jaw relationship: part_of UBERON:0008895 {source="VHOG"} ! splanchnocranium property_value: UBPROP:0000003 "Subsequent vertebrate evolution has also involved major alterations to the pharynx; perhaps the most notable occurred with the evolution of the gnathostomes. This involved substantial modifications to the most anterior pharyngeal segments, with the jaw forming from the first, anterior, pharyngeal segment, while the second formed its supporting apparatus, the hyoid.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0000511", ontology="VHOG", source="DOI:10.1046/j.1469-7580.2001.19910133.x Graham A. The development and evolution of the pharyngeal arches. J Anat (2001)", source="http://bgee.unil.ch/"} [Term] id: UBERON:0011088 name: ligament of knee joint namespace: uberon def: "A ligament that is part of a knee joint." [OBOL:automatic] subset: human_reference_atlas synonym: "knee joint ligament" EXACT [FMA:44580] xref: FMA:44580 xref: SCTID:182440009 is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001485 ! knee joint relationship: part_of UBERON:0001485 ! knee joint property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0011090 name: skeleton of right pelvic girdle namespace: uberon def: "A skeleton of pelvic girdle that is part of a right pelvic girdle region." [OBOL:automatic] xref: FMA:87593 is_a: UBERON:0007832 ! pelvic girdle skeleton intersection_of: UBERON:0007832 ! pelvic girdle skeleton intersection_of: part_of UBERON:0011092 ! right pelvic girdle region relationship: part_of UBERON:0011092 ! right pelvic girdle region [Term] id: UBERON:0011091 name: skeleton of left pelvic girdle namespace: uberon def: "A skeleton of pelvic girdle that is part of a left pelvic girdle region." [OBOL:automatic] xref: FMA:87594 is_a: UBERON:0007832 ! pelvic girdle skeleton intersection_of: UBERON:0007832 ! pelvic girdle skeleton intersection_of: part_of UBERON:0011093 ! left pelvic girdle region relationship: part_of UBERON:0011093 ! left pelvic girdle region [Term] id: UBERON:0011092 name: right pelvic girdle region namespace: uberon def: "A pelvic girdle region that is in the right side of a multicellular organism." [OBOL:automatic] synonym: "right pelvic girdle" EXACT INCONSISTENT [FMA:16582] xref: FMA:16582 is_a: UBERON:0001271 ! pelvic girdle region intersection_of: UBERON:0001271 ! pelvic girdle region intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: has_skeleton UBERON:0011090 ! skeleton of right pelvic girdle relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0011093 name: left pelvic girdle region namespace: uberon def: "A pelvic girdle region that is in the left side of a multicellular organism." [OBOL:automatic] synonym: "left pelvic girdle" EXACT INCONSISTENT [FMA:16583] xref: FMA:16583 is_a: UBERON:0001271 ! pelvic girdle region intersection_of: UBERON:0001271 ! pelvic girdle region intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: has_skeleton UBERON:0011091 ! skeleton of left pelvic girdle relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0011094 name: vertebra cartilage element namespace: uberon def: "The cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165, VSAO:0000184] synonym: "vertebral cartilage condensation" EXACT [VHOG:0000584] xref: EMAPA:32669 xref: VHOG:0000584 is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0011095 ! vertebra pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0002412 ! vertebra property_value: RO:0002175 NCBITaxon:7764 {notes="vertebra-like cartilage in hagfish are homologous to gnathostome vertebrae. mesenchymal cells express Pax1/9 and Twist", source="PMC3157150"} property_value: UBPROP:0000012 "This class is a superclass of individual vertebral cartilage condensations. Note that EHDAA2 represents these as condensation groups" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0011095 name: vertebra pre-cartilage condensation namespace: uberon def: "The pre-cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, http://orcid.org/0000-0002-6601-2165, VSAO:0000184] synonym: "vertebral pre-cartilage condensation" EXACT [VHOG:0000582] xref: EMAPA:32671 xref: VHOG:0000582 is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0002412 ! vertebra [Term] id: UBERON:0011104 name: epiphysis of fifth metacarpal bone namespace: uberon def: "An epiphysis that is part of a metacarpal bone of digit 5." [OBOL:automatic] synonym: "fifth metacarpal bone epiphysis" EXACT [FMA:86330] synonym: "metacarpal 5 epiphysis" EXACT [] xref: FMA:86330 is_a: UBERON:0004390 ! epiphysis of metacarpal bone intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003649 ! metacarpal bone of digit 5 relationship: part_of UBERON:0003649 ! metacarpal bone of digit 5 [Term] id: UBERON:0011107 name: synovial joint of pelvic girdle namespace: uberon def: "A synovial joint that is part of a pelvic girdle region." [OBOL:automatic] synonym: "joint of pelvic girdle" EXACT [] synonym: "pelvic girdle joint" EXACT [FMA:35173] xref: FMA:35173 xref: NCIT:C32890 xref: UMLS:C0827002 {source="ncithesaurus:Joint_of_the_Pelvic_Girdle"} is_a: UBERON:0002217 ! synovial joint is_a: UBERON:0008114 ! joint of girdle intersection_of: UBERON:0002217 ! synovial joint intersection_of: part_of UBERON:0001271 ! pelvic girdle region relationship: connects UBERON:0007830 ! pelvic girdle bone/zone relationship: part_of UBERON:0001271 ! pelvic girdle region [Term] id: UBERON:0011108 name: synovial joint of pectoral girdle namespace: uberon def: "A synovial joint that is part of a pectoral girdle region." [OBOL:automatic] synonym: "joint of shoulder girdle" EXACT [] synonym: "pectoral girdle joint" EXACT [FMA:35243] xref: FMA:35243 xref: SCTID:303080001 is_a: UBERON:0002217 ! synovial joint is_a: UBERON:0008114 ! joint of girdle intersection_of: UBERON:0002217 ! synovial joint intersection_of: part_of UBERON:0001421 ! pectoral girdle region relationship: connects UBERON:0007829 ! pectoral girdle bone relationship: part_of UBERON:0001421 ! pectoral girdle region property_value: UBPROP:0000012 "in FMA, these are part of the bony pectoral girdle" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0011110 name: humeroulnar joint namespace: uberon def: "The humeroulnar joint, is part of the elbow-joint or the Olecron Joint, between the ulna and humerus bones is the simple hinge-joint, which allows for movements of flexion, extension and circumduction. The Humero-Ulnar Joint is the junction of trochlear notch of the ulna and the trochlea of the humerus. Owing to the obliquity of the trochlea of the humerus, this movement does not take place in the antero-posterior plane of the body of the humerus. When the forearm is extended and supinated, the axis of the arm and forearm are not in the same line; the arm forms an obtuse angle with the forearm. During flexion, however, the forearm and the hand tend to approach the middle line of the body, and thus enable the hand to be easily carried to the face. The accurate adaptation of the trochlea of the humerus, with its prominences and depressions, to the semilunar notch of the ulna, prevents any lateral movement. Flexion is produced by the action of the Biceps brachii and Brachialis, assisted by the Brachioradialis, with a tiny contribution from the muscles arising from the medial epicondyle of the humerus. Extension is produced by the Triceps brachii and AnconC&us, with a tiny contribution from the muscles arising from the lateral epicondyle of the humerus, such as the Extensor digitorum communis." [Wikipedia:Humeroulnar_joint] subset: pheno_slim synonym: "articulatio humeroulnaris" EXACT LATIN [FMA:TA] synonym: "humero-ulnar joint" EXACT [FMA:38854] xref: FMA:38854 xref: SCTID:303064006 xref: Wikipedia:Humeroulnar_joint is_a: UBERON:0003839 ! forelimb joint is_a: UBERON:0011139 ! synovial limb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000976 ! humerus intersection_of: connects UBERON:0001424 ! ulna relationship: connects UBERON:0000976 ! humerus relationship: connects UBERON:0001424 ! ulna relationship: part_of UBERON:0001490 {source="FMA"} ! elbow joint property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray329.png" xsd:anyURI [Term] id: UBERON:0011111 name: humeroradial joint namespace: uberon def: "A hinge joint between the head of the radius and the capitulum of the humerus." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Humeroradial_joint] subset: pheno_slim synonym: "articulatio humeroradialis" EXACT LATIN [Wikipedia:Humeroradial_joint] synonym: "humero-radial joint" EXACT [] xref: FMA:38855 xref: SCTID:182171008 xref: Wikipedia:Humeroradial_joint is_a: UBERON:0003839 ! forelimb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000976 ! humerus intersection_of: connects UBERON:0001423 ! radius bone relationship: connects UBERON:0000976 ! humerus relationship: connects UBERON:0001423 ! radius bone relationship: part_of UBERON:0001490 {source="FMA"} ! elbow joint property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/9/97/Gray329.png" xsd:anyURI [Term] id: UBERON:0011112 name: tibiofibular joint namespace: uberon def: "A joint that connects the tibia and the fibula." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Tibiofibular_joint] synonym: "fibulatibial joint" EXACT [] synonym: "fibulotibial joint" EXACT [] synonym: "tibiafibular joint" EXACT [] xref: FMA:35181 xref: SCTID:244554002 xref: Wikipedia:Tibiofibular_joint is_a: UBERON:0002210 {source="FMA"} ! syndesmosis is_a: UBERON:0003840 ! hindlimb joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0001446 ! fibula intersection_of: part_of UBERON:0003823 ! hindlimb zeugopod relationship: connects UBERON:0000979 ! tibia relationship: connects UBERON:0001446 ! fibula relationship: part_of UBERON:0003823 ! hindlimb zeugopod property_value: editor_note "we include location as part of the logical definition to prevent accidental classification of ankle joints as tibiofibular joints" xsd:string [Term] id: UBERON:0011117 name: superior tibiofibular joint namespace: uberon def: "The superior tibiofibular articulation is an arthrodial joint between the lateral condyle of the tibia and the head of the fibula. The contiguous surfaces of the bones present flat, oval facets covered with cartilage and connected together by an articular capsule and by anterior and posterior ligaments. When the term 'tibiofibular articulation' is used without a modifier, it refers to the superior, and not the inferior tibiofibular articulation." [Wikipedia:Superior_tibiofibular_joint] synonym: "articulatio tibiofibularis" RELATED LATIN [Wikipedia:Superior_tibiofibular_joint] synonym: "proximal tibiofibular joint" EXACT [FMA:35184] synonym: "proximal tibiofibular joint" RELATED [Wikipedia:Superior_tibiofibular_joint] synonym: "proximal tibiofibular syndesmosis" RELATED [FMA:35184] synonym: "superior tibiofibular articulation" RELATED [Wikipedia:Superior_tibiofibular_joint] synonym: "tibiofibular joint" BROAD [Wikipedia:Superior_tibiofibular_joint] xref: FMA:35184 xref: SCTID:182208008 xref: Wikipedia:Superior_tibiofibular_joint is_a: UBERON:0011112 ! tibiofibular joint intersection_of: UBERON:0011112 ! tibiofibular joint intersection_of: connects UBERON:0008775 ! proximal epiphysis of fibula intersection_of: connects UBERON:0009985 ! lateral condyle of femur relationship: connects UBERON:0008775 ! proximal epiphysis of fibula relationship: connects UBERON:0009985 ! lateral condyle of femur property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/a/a8/Gray347.png" xsd:anyURI [Term] id: UBERON:0011118 name: tarsometatarsal joint namespace: uberon def: "The tarsometatarsal articulations are arthrodial joints in the pes." [Wikipedia:Tarsometatarsal_articulations] subset: pheno_slim synonym: "articulationes tarsometatarsales" RELATED LATIN [Wikipedia:Tarsometatarsal_articulations] synonym: "cuboideometatarsal" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "Lisfranc joint" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "tarso-metatarsal join" EXACT [] synonym: "tarsometatarsal" RELATED [Wikipedia:Tarsometatarsal_articulations] synonym: "tarsometatarsal articulation" RELATED [Wikipedia:Tarsometatarsal_articulations] xref: FMA:35216 xref: SCTID:182222008 xref: Wikipedia:Tarsometatarsal_articulations is_a: UBERON:0001487 ! pes joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001447 ! tarsal bone intersection_of: connects UBERON:0001448 ! metatarsal bone relationship: connects UBERON:0001447 ! tarsal bone relationship: connects UBERON:0001448 ! metatarsal bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/8/8e/Gray355.png" xsd:anyURI property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray358.png" xsd:anyURI [Term] id: UBERON:0011119 name: carpometacarpal joint namespace: uberon def: "The carpometacarpal joints (CMC) are joints in the wrist that articulates the distal row of carpal bones and the proximal bases of the metacarpal bones." [Wikipedia:Carpometacarpal_joint] synonym: "articulationes carpometacarpeæ" EXACT LATIN [Wikipedia:Carpometacarpal_joint] synonym: "carpometacarpal" BROAD [Wikipedia:Carpometacarpal_joint] synonym: "carpometacarpal articulation" RELATED [Wikipedia:Carpometacarpal_joint] synonym: "CMJ" BROAD [Wikipedia:Carpometacarpal_joint] xref: FMA:35287 xref: MESH:D052737 xref: NCIT:C32265 xref: SCTID:361842002 xref: UMLS:C0224620 {source="ncithesaurus:Carpometacarpal_Joint"} xref: Wikipedia:Carpometacarpal_joint is_a: UBERON:0001489 ! manus joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001435 ! carpal bone intersection_of: connects UBERON:0002374 ! metacarpal bone relationship: connects UBERON:0001435 ! carpal bone relationship: connects UBERON:0002374 ! metacarpal bone property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7c/Gray335.png" xsd:anyURI [Term] id: UBERON:0011120 name: laryngeal joint namespace: uberon def: "A skeletal joint that connects a laryngeal cartilage." [OBOL:automatic] synonym: "joint of larynx" EXACT [FMA:55100] synonym: "laryngeal articulation" EXACT [FMA:55100] xref: FMA:55100 is_a: UBERON:0002217 {source="FMA"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001739 ! laryngeal cartilage relationship: connects UBERON:0001739 ! laryngeal cartilage relationship: part_of UBERON:0010323 ! cranial skeletal system [Term] id: UBERON:0011131 name: intermetacarpal joint namespace: uberon def: "A skeletal joint that connects two adjacent metacarpals[FMA,modified]." [FMA:35288] synonym: "intermetacarpal" RELATED [Wikipedia:Intermetacarpal_articulations] synonym: "intermetacarpal articulation" RELATED [Wikipedia:Intermetacarpal_articulations] xref: FMA:35288 xref: SCTID:303065007 xref: Wikipedia:Intermetacarpal_articulations is_a: UBERON:0001489 ! manus joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002374 {cardinality="2"} ! metacarpal bone relationship: connects UBERON:0002374 {notes="two adjacent metacarpals"} ! metacarpal bone relationship: part_of UBERON:0004453 ! metacarpus region [Term] id: UBERON:0011132 name: intercarpal joint namespace: uberon def: "A skeletal joint that connects two carpal bones." [http://orcid.org/0000-0002-6601-2165] synonym: "carpal joint" EXACT [FMA:35292] synonym: "intercarpal" RELATED [Wikipedia:Intercarpal_articulations] synonym: "intercarpal articulation" RELATED [Wikipedia:Intercarpal_articulations] synonym: "midcarpal articulation" RELATED [Wikipedia:Intercarpal_articulations] xref: FMA:35292 xref: NCIT:C32264 xref: SCTID:182176003 xref: UMLS:C1262468 {source="ncithesaurus:Carpal_Joint"} xref: Wikipedia:Intercarpal_articulations is_a: UBERON:0001489 ! manus joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001435 {cardinality="2"} ! carpal bone relationship: connects UBERON:0001435 {notes="two adjacent carpals"} ! carpal bone relationship: part_of UBERON:0004452 {source="FMA"} ! carpal region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/37/Gray336.png" xsd:anyURI [Term] id: UBERON:0011133 name: intermetatarsal joint namespace: uberon def: "A joint that connects two adjacent metatarsals." [Wikipedia:Intermetatarsal_articulations] xref: FMA:35219 xref: SCTID:361868009 xref: Wikipedia:Intermetatarsal_articulations is_a: UBERON:0001487 ! pes joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001448 {cardinality="2"} ! metatarsal bone relationship: connects UBERON:0001448 {notes="two adjacent metatarsals"} ! metatarsal bone relationship: part_of UBERON:0000983 ! metatarsus region property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/d/dc/Gray358.png" xsd:anyURI property_value: UBPROP:0000008 "In humans: The base of the first metatarsal is not connected with that of the second by any ligaments; in this respect the great toe resembles the thumb" xsd:string {source="WP"} [Term] id: UBERON:0011134 name: nonsynovial joint namespace: uberon def: "Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis." [FMA:7491] synonym: "solid joint" EXACT [FMA:7491] xref: FMA:7491 is_a: UBERON:0000982 {source="FMA"} ! skeletal joint [Term] id: UBERON:0011135 name: intervertebral cartilage namespace: uberon def: "A cartilage element that lies between two successive vertebral centra." [ISBN:0073040584] xref: AAO:0000795 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: adjacent_to UBERON:0001075 {cardinality="2"} ! bony vertebral centrum relationship: adjacent_to UBERON:0001075 {notes="between two centra"} ! bony vertebral centrum relationship: part_of UBERON:0001468 {source="FMA", source="MA"} ! intervertebral joint property_value: UBPROP:0000001 "Block of cartilage, which usually ossifies, that lies between successive vertebral centra.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000795", ontology="AAO", source="AAO:Trueb_1973"} [Term] id: UBERON:0011136 name: ligament of vertebral column namespace: uberon def: "Ligament that joins successive centra. Important in controlling the stiffness of the vertebral column when it flexes." [ISBN:0073040584] synonym: "intervertebral ligament" BROAD [] synonym: "vertebral centrum ligament" BROAD [] synonym: "vertebral column ligament" EXACT [FMA:31892] xref: FMA:31892 xref: SCTID:244590009 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: attaches_to UBERON:0001075 ! bony vertebral centrum relationship: attaches_to UBERON:0001075 ! bony vertebral centrum relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0001130 ! vertebral column [Term] id: UBERON:0011137 name: axial skeletal system namespace: uberon def: "Subdivision of the skeletal system which consists of the axial skeleton plus associated joints." [https://orcid.org/0000-0002-6601-2165] xref: FMA:7483 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: has_part UBERON:0000982 ! skeletal joint relationship: has_part UBERON:0005944 ! axial skeleton plus cranial skeleton property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI [Term] id: UBERON:0011138 name: postcranial axial skeletal system namespace: uberon def: "Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints." [https://github.com/obophenotype/uberon/issues/44, https://orcid.org/0000-0002-6601-2165] synonym: "axial skeletal system" BROAD [https://github.com/obophenotype/uberon/wiki/The-axial-skeleton] synonym: "post-cranial axial skeletal system" EXACT [] xref: FMA:302077 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: develops_from UBERON:0003089 {source="cjm"} ! sclerotome relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall property_value: seeAlso "http://purl.obolibrary.org/obo/uberon/docs/The-axial-skeleton" xsd:anyURI [Term] id: UBERON:0011139 name: synovial limb joint namespace: uberon def: "Any synovial joint that is part of a (free) limb." [https://orcid.org/0000-0002-6601-2165] comment: Most limb joints are synovial, but a few such as the tibiofibular joints are syndesmoses. synonym: "synovial joint of free limb segment" EXACT [FMA:258776] xref: FMA:258776 is_a: UBERON:0002217 ! synovial joint is_a: UBERON:0003657 ! limb joint intersection_of: UBERON:0002217 ! synovial joint intersection_of: part_of UBERON:0002101 ! limb [Term] id: UBERON:0011141 name: appendicular ossicle namespace: uberon def: "Ossicle that is part of the appendicular skeleton." [PSPUB:0000169, VSAO:0000131] comment: Examples of appendicular ossicles include the patella and meniscus of the knee joint. synonym: "ossicle of appendicular skeleton" EXACT [OBOL:automatic] xref: VSAO:0000131 xref: XAO:0004194 is_a: UBERON:0010911 ! ossicle intersection_of: UBERON:0010911 ! ossicle intersection_of: part_of UBERON:0002091 ! appendicular skeleton relationship: part_of UBERON:0002091 ! appendicular skeleton [Term] id: UBERON:0011142 name: axial ossicle namespace: uberon def: "Ossicle that is part of the axial skeleton." [PSPUB:0000169, VSAO:0000133] comment: Examples of axial ossicles include the ossified tendons adjacent to the neural spines of the vertebral column. synonym: "ossicle of axial skeleton" EXACT [OBOL:automatic] synonym: "ossicle of postcranial-axial skeleton" EXACT [OBOL:automatic] synonym: "vertebral ossicle" RELATED [OBOL:automatic] xref: VSAO:0000133 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010911 ! ossicle intersection_of: UBERON:0010911 ! ossicle intersection_of: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0002090 ! postcranial axial skeleton [Term] id: UBERON:0011143 name: upper urinary tract namespace: uberon def: "Subdivision of urinary system which consists of the kidney and the ureters." [FMA:45658] subset: pheno_slim xref: FMA:45658 xref: galen:UpperUrinaryTract xref: NCIT:C61107 xref: SCTID:181413006 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0011216 ! organ system subdivision is_a: UBERON:0015212 ! lateral structure relationship: has_part UBERON:0000056 ! ureter relationship: has_part UBERON:0002113 ! kidney relationship: in_lateral_side_of UBERON:0001008 {source="FMA-abduced-lr"} ! renal system relationship: part_of UBERON:0001008 {source="FMA"} ! renal system [Term] id: UBERON:0011148 name: submucosal gland namespace: uberon def: "Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue." [BTO:0003751, Wikipedia:Submucosal_glands] xref: BTO:0003751 xref: EMAPA:37970 {source="MA:th"} xref: Wikipedia:Submucosal_glands is_a: UBERON:0000414 ! mucous gland intersection_of: UBERON:0000414 ! mucous gland intersection_of: located_in UBERON:0000009 ! submucosa relationship: continuous_with UBERON:0003350 {notes="perforates"} ! epithelium of mucosa relationship: located_in UBERON:0000009 ! submucosa [Term] id: UBERON:0011156 name: facial skeleton namespace: uberon def: "Subdivision of skull that consists of the facial bones." [http://www.bartleby.com/107/37.html, https://orcid.org/0000-0002-6601-2165, MP:0005274, Wikipedia:Facial_skeleton] subset: pheno_slim synonym: "facial bone" RELATED [MA:0000318] synonym: "facial skeleton" EXACT [FMA:53673] synonym: "ossa facialia" RELATED LATIN [Wikipedia:Facial_skeleton] synonym: "ossa faciei" RELATED LATIN [Wikipedia:Facial_skeleton] synonym: "viscerocranium" RELATED INCONSISTENT [MA:0000318] xref: EHDAA2:0002206 xref: EHDAA:8361 xref: EMAPA:18022 xref: FMA:53673 xref: MA:0000318 xref: Wikipedia:Facial_skeleton is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0011158 {source="FMA"} ! primary subdivision of skull relationship: part_of UBERON:0001456 {source="FMA"} ! face property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/77/Illu_facial_bones.jpg" xsd:anyURI [Term] id: UBERON:0011158 name: primary subdivision of skull namespace: uberon def: "The skull can be divided into two: the neurocranium and the facial skeleton." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "skull subdivision" EXACT [FMA:54964] synonym: "subdivision of skull" EXACT [FMA:54964] xref: FMA:54964 is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: part_of UBERON:0003129 ! skull [Term] id: UBERON:0011159 name: primary subdivision of cranial skeletal system namespace: uberon subset: non_informative is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system relationship: part_of UBERON:0010323 ! cranial skeletal system [Term] id: UBERON:0011160 name: nasal suture namespace: uberon def: "A suture joining a nasal bone to another bone." [http://orcid.org/0000-0002-6601-2165] xref: SCTID:368992007 is_a: UBERON:0009199 ! facial suture intersection_of: UBERON:0009199 ! facial suture intersection_of: connects UBERON:0001681 ! nasal bone relationship: connects UBERON:0001681 ! nasal bone [Term] id: UBERON:0011162 name: supraoccipital cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a supraoccipital bone." [OBOL:automatic] synonym: "non-squamous part of supraoccipital bone" RELATED [EMAPA:18341] synonym: "supra-occipital cartilage condensation" EXACT [] synonym: "supraoccipital cartilage condensation" EXACT [EMAPA:18341] xref: EMAPA:18341 is_a: UBERON:0003932 ! cartilage element of chondrocranium is_a: UBERON:0015015 ! supraoccipital endochondral element intersection_of: UBERON:0015015 ! supraoccipital endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0011163 ! supraoccipital pre-cartilage condensation [Term] id: UBERON:0011163 name: supraoccipital pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a supraoccipital bone." [OBOL:automatic] synonym: "supra-occipital pre-cartilage condensation" EXACT [EHDAA2:0001963] xref: EHDAA2:0001963 xref: EHDAA:9534 is_a: UBERON:0005253 ! head mesenchyme is_a: UBERON:0005866 ! pre-cartilage condensation is_a: UBERON:0015015 ! supraoccipital endochondral element intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0004747 ! supraoccipital bone relationship: develops_from UBERON:0009617 {source="EHDAA2-inferred"} ! head paraxial mesoderm relationship: has_potential_to_develop_into UBERON:0004747 ! supraoccipital bone [Term] id: UBERON:0011164 name: neurocranium bone namespace: uberon def: "A bone that is part of a neurocranium [Automatically generated definition]." [OBOL:automatic] synonym: "chondrocranium bone" EXACT [MA:0001478] xref: EMAPA:35238 xref: MA:0001478 xref: SCTID:120229002 is_a: UBERON:0004766 ! cranial bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0001703 ! neurocranium [Term] id: UBERON:0011171 name: joint connecting upper and lower jaws namespace: uberon def: "Synovial joint that articulates bones of upper and lower jaw." [http://evolution.berkeley.edu/evolibrary/article/evograms_05, https://orcid.org/0000-0002-6601-2165] synonym: "craniomandibular joint" NARROW [] synonym: "jaw joint" BROAD [] xref: NCIT:C32888 is_a: UBERON:0002217 {source="abduced"} ! synovial joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0003277 ! skeleton of upper jaw intersection_of: connects UBERON:0003278 ! skeleton of lower jaw relationship: connects UBERON:0003277 ! skeleton of upper jaw relationship: connects UBERON:0003278 ! skeleton of lower jaw property_value: UBPROP:0000008 "Some synapsids retained two pairs of jaw joints - quadrate-articular and tempero-mandibular, but this unusual paired condition did not last long" xsd:string {source="http://evolution.berkeley.edu"} [Term] id: UBERON:0011185 name: gastrointestinal sphincter namespace: uberon def: "A sphincter muscle that is part of the gastrointestinal system." [OBOL:automatic] xref: NCIT:C32669 xref: UMLS:C1517464 {source="ncithesaurus:Gastrointestinal_Sphincter"} is_a: UBERON:0004590 ! sphincter muscle is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0005409 ! alimentary part of gastrointestinal system relationship: part_of UBERON:0005409 ! alimentary part of gastrointestinal system [Term] id: UBERON:0011187 name: ventral tubercle of humerus namespace: uberon def: "The greater tubercle of the humerus is situated lateral to the head of the humerus and posteriolateral to the lesser tubercle. Its upper surface is rounded and marked by three flat impressions. the highest of these gives ('superior facet') insertion to the Supraspinatus the middle ('middle facet') to the Infraspinatus. the lowest one ('inferior facet'), and the body of the bone for about 2.5 cm. below it, to the Teres minor. The lateral surface of the greater tubercle is convex, rough, and continuous with the lateral surface of the body. Between the greater tubercle and the lesser tubercle is the intertubercular sulcus (bicipital groove)." [Wikipedia:Greater_tubercle] synonym: "greater tubercle" EXACT [FMA:23390] synonym: "greater tubercle of humerus" EXACT [FMA:23390] synonym: "greater tubercle of the humerus" RELATED [Wikipedia:Greater_tubercle] synonym: "greater tuberosity" RELATED [Wikipedia:Greater_tubercle] synonym: "greater tuberosity of humerus" EXACT [FMA:23390] synonym: "tuberculum majus" EXACT LATIN [FMA:TA] synonym: "tuberculum majus humeri" EXACT [Wikipedia:Greater_tubercle] xref: FMA:23390 xref: NCIT:C32700 xref: SCTID:181934009 xref: UMLS:C1512275 {source="ncithesaurus:Greater_Tuberosity"} xref: Wikipedia:Greater_tubercle is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005813 {source="FMA"} ! tubercle is_a: UBERON:4100000 ! skeletal element projection relationship: part_of UBERON:0004411 {source="FMA"} ! proximal epiphysis of humerus property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3b/Gray326.png" xsd:anyURI [Term] id: UBERON:0011189 name: lamina propria of large intestine namespace: uberon def: "A lamina propria that is part of a large intestine." [OBOL:automatic] subset: human_reference_atlas synonym: "lamina propria of mucosa of large intestine" EXACT [FMA:15654] synonym: "large intestinal lamina propria" EXACT [] synonym: "large intestine lamina propria" EXACT [FMA:15654] xref: FMA:15654 xref: NCIT:C49298 xref: UMLS:C1708644 {source="ncithesaurus:Large_Intestinal_Lamina_Propria"} is_a: UBERON:0004780 ! gastrointestinal system lamina propria intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001207 {source="FMA"} ! mucosa of large intestine property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0011198 name: muscle layer of large intestine namespace: uberon def: "A muscle layer that is part of a large intestine." [OBOL:automatic] synonym: "muscular coat of large intestine" EXACT [FMA:14971] synonym: "muscular layer of large intestine" EXACT [FMA:14971] synonym: "muscularis externa of large intestine" EXACT [FMA:14971] synonym: "tunica muscularis intestini crassi" EXACT LATIN [FMA:TA] xref: FMA:14971 xref: NCIT:C32927 xref: UMLS:C0734205 {source="ncithesaurus:Large_Intestinal_Muscular_Coat"} is_a: UBERON:0012367 ! muscle layer of intestine intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0000059 ! large intestine relationship: part_of UBERON:0001169 {source="FMA"} ! wall of large intestine [Term] id: UBERON:0011200 name: sacrococcygeal symphysis namespace: uberon def: "The sacrococcygeal symphysis (sacrococcygeal articulation, articulation of the sacrum and coccyx) is an amphiarthrodial joint, formed between the oval surface at the apex of the sacrum, and the base of the coccyx. It is a slightly moveable joint which is frequently, partially or completely, obliterated in old age, homologous with the joints between the bodies of the vertebrae." [Wikipedia:Sacrococcygeal_symphysis] synonym: "sacrococcygeal joint" EXACT [FMA:16210] synonym: "sacrococcygeal joint" RELATED [Wikipedia:Sacrococcygeal_symphysis] xref: FMA:16210 xref: NCIT:C33506 xref: UMLS:C0224593 {source="ncithesaurus:Sacrococcygeal_Joint"} xref: Wikipedia:Sacrococcygeal_symphysis is_a: UBERON:0001468 {source="FMA"} ! intervertebral joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001350 ! coccyx intersection_of: connects UBERON:0003690 ! fused sacrum relationship: connects UBERON:0001350 ! coccyx relationship: connects UBERON:0003690 ! fused sacrum property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/7/7f/Gray320.png" xsd:anyURI [Term] id: UBERON:0011201 name: muscle layer of small intestine namespace: uberon def: "A muscle layer that is part of a small intestine." [OBOL:automatic] synonym: "muscular coat of small intestine" EXACT [FMA:14932] synonym: "muscular layer of small intestine" EXACT [FMA:14932] synonym: "muscularis externa of small intestine" EXACT [FMA:14932] synonym: "small intestine muscularis propria" EXACT [FMA:14932] synonym: "tunica muscularis (intestinum tenue)" EXACT [FMA:14932] synonym: "tunica muscularis intestini tenuis" EXACT LATIN [FMA:TA] xref: FMA:14932 xref: NCIT:C33569 xref: SCTID:362145004 xref: UMLS:C0227269 {source="ncithesaurus:Small_Intestinal_Muscular_Coat"} is_a: UBERON:0012367 ! muscle layer of intestine intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0002108 ! small intestine relationship: part_of UBERON:0001168 {source="FMA"} ! wall of small intestine [Term] id: UBERON:0011215 name: central nervous system cell part cluster namespace: uberon def: "A multi cell part structure that is part of a central nervous system." [OBOL:automatic] subset: upper_level synonym: "cell part cluster of neuraxis" EXACT [FMA:83143] synonym: "neuraxis layer" EXACT [FMA:83143] xref: FMA:83143 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005162 ! multi cell part structure intersection_of: UBERON:0005162 ! multi cell part structure intersection_of: part_of UBERON:0001017 ! central nervous system relationship: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0011216 name: organ system subdivision namespace: uberon def: "A subdivision of an anatomical system." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy subset: upper_level xref: FBbt:00007330 xref: FMA:67509 xref: SCTID:91690000 is_a: UBERON:0010000 {source="FBbt"} ! multicellular anatomical structure relationship: part_of UBERON:0000467 ! anatomical system property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0011222 name: intra-ocular muscle namespace: uberon synonym: "intrinsic muscle of eyeball" EXACT [] synonym: "intrinsic ocular muscle" EXACT [EMAPA:18808] xref: AAO:0010038 xref: EMAPA:18808 xref: FMA:49150 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004277 ! eye muscle relationship: part_of UBERON:0003386 {source="EMAPA"} ! smooth muscle of eye property_value: UBPROP:0000001 "Muscles within the eye (bulbus oculi).[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0010038", ontology="AAO", source="AAO:EJS"} [Term] id: UBERON:0011233 name: synovial membrane of synovial tendon sheath namespace: uberon def: "Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa." [FMA:45087, Wikipedia:Synovial_sheath] comment: Alternate def: A synovial sheath is a layer of a tendon sheath containing tendons in the hand and foot. They lie internal to the fibrous tendon sheaths. An example is the common synovial sheath for the flexor tendons. [Wikipedia:Synovial_sheath] synonym: "synovium" BROAD [BTO:0001823] xref: BTO:0001823 xref: FMA:40878 xref: Wikipedia:Synovial_sheath is_a: UBERON:0007616 ! layer of synovial tissue intersection_of: UBERON:0007616 ! layer of synovial tissue intersection_of: bounding_layer_of UBERON:0000304 ! tendon sheath relationship: bounding_layer_of UBERON:0000304 ! tendon sheath relationship: part_of UBERON:0000304 ! tendon sheath [Term] id: UBERON:0011234 name: fibrous membrane of synovial tendon sheath namespace: uberon xref: FMA:40877 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: bounding_layer_of UBERON:0000304 ! tendon sheath intersection_of: composed_primarily_of UBERON:0011824 ! fibrous connective tissue relationship: bounding_layer_of UBERON:0000304 ! tendon sheath relationship: composed_primarily_of UBERON:0011824 ! fibrous connective tissue relationship: part_of UBERON:0000304 ! tendon sheath [Term] id: UBERON:0011241 name: ethmoid region namespace: uberon def: "The most anterior region of the braincase. Provides structural support for peripheral olfactory organ." [http://palaeos.com/vertebrates/bones/braincase/ethmoid.html, UBERONREF:0000007] xref: AAO:0000986 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0034921 ! multi organ part structure relationship: has_developmental_contribution_from UBERON:0005945 ! neurocranial trabecula relationship: part_of UBERON:0003112 ! olfactory region property_value: IAO:0000232 "currently this is not restricted to skeletal elements, unlike UBERONREF:0000007" xsd:string [Term] id: UBERON:0011249 name: appendicular skeletal system namespace: uberon def: "Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints." [https://orcid.org/0000-0002-6601-2165] xref: FMA:7484 xref: VHOG:0001666 xref: VSAO:0000306 is_a: UBERON:0000075 ! subdivision of skeletal system relationship: has_part UBERON:0000982 ! skeletal joint relationship: has_part UBERON:0002091 ! appendicular skeleton property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Appendages-and-the-appendicular-skeleton" xsd:anyURI property_value: UBPROP:0000001 "Skeletal system which consists of the appendicular skeleton plus associated joints.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000306", ontology="VSAO", source="https://orcid.org/0000-0002-6601-2165"} [Term] id: UBERON:0011250 name: autopod bone namespace: uberon def: "A bone that is part of a autopod region. Note that this incudes the carpal and tarsal bones." [https://orcid.org/0000-0002-6601-2165] is_a: UBERON:0002428 ! limb bone is_a: UBERON:0015063 ! autopod endochondral element intersection_of: UBERON:0015063 ! autopod endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015064 ! autopod cartilage property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern" xsd:anyURI [Term] id: UBERON:0011265 name: carpometacarpal joint of digit 1 namespace: uberon def: "A carpometacarpal joint that connects to metacarpal 1." [Wikipedia:Carpometacarpal_joint#Thumb] subset: pheno_slim synonym: "carpometacarpal joint of digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "carpometacarpal joint of pollex" EXACT [FMA:35421] synonym: "carpometacarpal joint of the thumb" RELATED [Wikipedia:Carpometacarpal_joint#Thumb] synonym: "carpometacarpal joint of thumb" EXACT [FMA:35421] synonym: "TMJ" RELATED INCONSISTENT [Wikipedia:Carpometacarpal_joint#Thumb] synonym: "trapeziometacarpal joint" RELATED [Wikipedia:Carpometacarpal_joint#Thumb] xref: FMA:35421 xref: SCTID:361843007 xref: Wikipedia:Carpometacarpal_joint#Thumb is_a: UBERON:0011119 ! carpometacarpal joint is_a: UBERON:0011965 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="Wikipedia"} ! saddle joint intersection_of: UBERON:0011119 ! carpometacarpal joint intersection_of: connects UBERON:0003645 ! metacarpal bone of digit 1 relationship: connects UBERON:0003645 ! metacarpal bone of digit 1 property_value: UBPROP:0000008 "In humans it connects the trapezium to the first metacarpal bone, plays an irreplaceable role in the normal functioning of the thumb. The most important joint connecting the wrist to the metacarpus, osteoarthritis of the TMC is a severely disabling condition; up to twenty times more common among old women than in average" xsd:string {source="WP"} [Term] id: UBERON:0011270 name: dorsal trunk namespace: uberon def: "The part of the trunk that is in the dorsum[cjm]." [UBERONREF:0000006, Wikipedia:Human_back] synonym: "back of trunk" EXACT [FMA:25056] synonym: "dorsal part of trunk" EXACT [] synonym: "dorsum of trunk" EXACT [FMA:25056] synonym: "trunk back" EXACT [FMA:25056] xref: EMAPA:35162 xref: FMA:25056 xref: MA:0000020 xref: Wikipedia:Human_back is_a: UBERON:0009569 {source="FMA"} ! subdivision of trunk relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum property_value: UBPROP:0000008 "In humans, the subdivision of trunk which is demarcated from the trunk proper by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines, the external surface of the posterior abdominal wall; together with the trunk proper, it constitutes the trunk[FMA]" xsd:string [Term] id: UBERON:0011272 name: embryonic skin basal layer namespace: uberon synonym: "basal cell layer of skin" RELATED [] synonym: "outer epithelium of body" RELATED [Wikipathways:WP2062] xref: EHDAA2:0001845 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0010371 ! ecto-epithelium relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0002199 {source="EHDAA2"} ! integument property_value: editor_note "compare with 'stratum basale of epidermis'. This class is the source for many adult structures - see WP2062. See also: 'enveloping layer of ectoderm'" xsd:string [Term] id: UBERON:0011273 name: nail of manual digit 1 namespace: uberon def: "A nail that is part of a manual digit 1." [OBOL:automatic] subset: pheno_slim synonym: "claw of digit 1 of fore-paw" EXACT [EMAPA:18734] synonym: "nail of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail of thumb" EXACT [FMA:54329] synonym: "nail plate of thumb" EXACT [FMA:54329] synonym: "thumb nail" EXACT [FMA:54329] xref: EMAPA:18734 xref: FMA:54329 xref: SCTID:181584008 is_a: UBERON:0009565 {source="FMA"} ! nail of manual digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0001463 ! manual digit 1 relationship: part_of UBERON:0001463 ! manual digit 1 [Term] id: UBERON:0011274 name: nail of manual digit 2 namespace: uberon def: "A nail that is part of a manual digit 2." [OBOL:automatic] synonym: "claw of digit 2 of fore-paw" EXACT [EMAPA:18735] synonym: "index finger nail" EXACT [FMA:54332] synonym: "nail of index finger" EXACT [FMA:54332] synonym: "nail of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail of second finger" EXACT [FMA:54332] synonym: "nail plate of index finger" EXACT [FMA:54332] xref: EMAPA:18735 xref: FMA:54332 xref: SCTID:181580004 is_a: UBERON:0009565 {source="FMA"} ! nail of manual digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003622 ! manual digit 2 relationship: part_of UBERON:0003622 ! manual digit 2 [Term] id: UBERON:0011275 name: nail of manual digit 3 namespace: uberon def: "A nail that is part of a manual digit 3." [OBOL:automatic] synonym: "claw of digit 3 of fore-paw" EXACT [EMAPA:18736] synonym: "middle finger nail" EXACT [FMA:54335] synonym: "nail of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail of middle finger" EXACT [FMA:54335] synonym: "nail of third finger" EXACT [FMA:54335] synonym: "nail plate of middle finger" EXACT [FMA:54335] xref: EMAPA:18736 xref: FMA:54335 xref: SCTID:181581000 is_a: UBERON:0009565 {source="FMA"} ! nail of manual digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003623 ! manual digit 3 relationship: part_of UBERON:0003623 ! manual digit 3 [Term] id: UBERON:0011276 name: nail of manual digit 4 namespace: uberon def: "A nail that is part of a manual digit 4." [OBOL:automatic] synonym: "claw of digit 4 of fore-paw" EXACT [EMAPA:18737] synonym: "nail of fourth finger" EXACT [FMA:54338] synonym: "nail of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail of ring finger" EXACT [FMA:54338] synonym: "nail plate of ring finger" EXACT [FMA:54338] synonym: "ring finger nail" EXACT [FMA:54338] xref: EMAPA:18737 xref: FMA:54338 xref: SCTID:181582007 is_a: UBERON:0009565 {source="FMA"} ! nail of manual digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003624 ! manual digit 4 relationship: part_of UBERON:0003624 ! manual digit 4 [Term] id: UBERON:0011277 name: nail of manual digit 5 namespace: uberon def: "A nail that is part of a manual digit 5." [OBOL:automatic] subset: pheno_slim synonym: "claw of digit 5 of fore-paw" EXACT [EMAPA:18738] synonym: "little finger nail" EXACT [FMA:54341] synonym: "nail of fifth finger" EXACT [FMA:54341] synonym: "nail of little finger" RELATED [FMA:54341] synonym: "nail of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail plate of little finger" EXACT [FMA:54341] xref: EMAPA:18738 xref: FMA:54341 xref: SCTID:181583002 is_a: UBERON:0009565 {source="FMA"} ! nail of manual digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003625 ! manual digit 5 relationship: part_of UBERON:0003625 ! manual digit 5 [Term] id: UBERON:0011278 name: nail of pedal digit 1 namespace: uberon def: "A nail that is part of a pedal digit 1." [OBOL:automatic] subset: pheno_slim synonym: "big toe nail" EXACT [FMA:54344] synonym: "claw of digit 1 of hind-paw" EXACT [EMAPA:18739] synonym: "nail of big toe" EXACT [FMA:54344] synonym: "nail of first toe" RELATED [FMA:54344] synonym: "nail of great toe" EXACT [FMA:54344] synonym: "nail of pedal digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail plate of big toe" EXACT [FMA:54344] xref: EMAPA:18739 xref: FMA:54344 xref: SCTID:181592004 is_a: UBERON:0009567 {source="FMA"} ! nail of pedal digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003631 ! pedal digit 1 relationship: part_of UBERON:0003631 ! pedal digit 1 [Term] id: UBERON:0011279 name: nail of pedal digit 2 namespace: uberon def: "A nail that is part of a pedal digit 2." [OBOL:automatic] synonym: "claw of digit 2 of hind-paw" EXACT [EMAPA:18740] synonym: "nail of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail of second toe" EXACT [FMA:54347] synonym: "nail plate of second toe" EXACT [FMA:54347] synonym: "second toe nail" EXACT [FMA:54347] xref: EMAPA:18740 xref: FMA:54347 xref: SCTID:181593009 is_a: UBERON:0009567 {source="FMA"} ! nail of pedal digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003632 ! pedal digit 2 relationship: part_of UBERON:0003632 ! pedal digit 2 [Term] id: UBERON:0011280 name: nail of pedal digit 3 namespace: uberon def: "A nail that is part of a pedal digit 3." [OBOL:automatic] synonym: "claw of digit 3 of hind-paw" EXACT [EMAPA:18741] synonym: "nail of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail of third toe" EXACT [FMA:54350] synonym: "nail plate of third toe" EXACT [FMA:54350] synonym: "third toe nail" EXACT [FMA:54350] xref: EMAPA:18741 xref: FMA:54350 xref: SCTID:181594003 is_a: UBERON:0009567 {source="FMA"} ! nail of pedal digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003633 ! pedal digit 3 relationship: part_of UBERON:0003633 ! pedal digit 3 [Term] id: UBERON:0011281 name: nail of pedal digit 4 namespace: uberon def: "A nail that is part of a pedal digit 4." [OBOL:automatic] synonym: "claw of digit 4 of hind-paw" EXACT [EMAPA:18742] synonym: "fourth toe nail" EXACT [FMA:54353] synonym: "nail of fourth toe" EXACT [FMA:54353] synonym: "nail of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail plate of fourth toe" EXACT [FMA:54353] xref: EMAPA:18742 xref: FMA:54353 xref: SCTID:181595002 is_a: UBERON:0009567 {source="FMA"} ! nail of pedal digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003634 ! pedal digit 4 relationship: part_of UBERON:0003634 ! pedal digit 4 [Term] id: UBERON:0011282 name: nail of pedal digit 5 namespace: uberon def: "A nail that is part of a pedal digit 5." [OBOL:automatic] subset: pheno_slim synonym: "claw of digit 5 of hind-paw" EXACT [EMAPA:18743] synonym: "little toe nail" EXACT [FMA:54356] synonym: "nail of fifth toe" EXACT [FMA:54356] synonym: "nail of little toe" EXACT [FMA:54356] synonym: "nail of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "nail plate of little toe" EXACT [FMA:54356] xref: EMAPA:18743 xref: FMA:54356 xref: SCTID:181596001 is_a: UBERON:0009567 {source="FMA"} ! nail of pedal digit intersection_of: UBERON:0001705 ! nail intersection_of: part_of UBERON:0003635 ! pedal digit 5 relationship: part_of UBERON:0003635 ! pedal digit 5 [Term] id: UBERON:0011298 name: submucosa of uterine tube namespace: uberon def: "The submucous layer of the wall of the uterine tube." [BTO:0002116] synonym: "submucosa of fallopian tube" EXACT [] synonym: "submucous layer of uterine tube" RELATED [BTO:0002116] synonym: "tela submucosa tubae uterinae" EXACT LATIN [BTO:0002116] synonym: "uterine submucosa" RELATED [] xref: BTO:0002116 xref: SCTID:245489008 is_a: UBERON:0000009 ! submucosa is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: part_of UBERON:0003889 ! fallopian tube [Term] id: UBERON:0011299 name: white matter of telencephalon namespace: uberon alt_id: UBERON:0013202 alt_id: UBERON:0022550 def: "A partion of white matter that is part of a telencephalon. This can be further subdivided in some species, for example, into hemisphere white matter and the corpus callosum." [https://orcid.org/0000-0002-6601-2165] synonym: "predominantly white regional part of telencephalon" EXACT [BIRNLEX:1075] synonym: "telencephalic tract/commissure" EXACT [ZFA:0000597] synonym: "telencephalic tracts" NARROW [TAO:0000597] synonym: "telencephalic white matter" EXACT [HBA:TELWM] xref: BIRNLEX:1075 xref: FMA:83930 xref: HBA:9219 xref: HBA:9230 xref: TAO:0000597 xref: ZFA:0000597 is_a: UBERON:0019261 ! white matter of forebrain intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0001893 ! telencephalon property_value: UBPROP:0000001 "CNS white matter that is part of the telencephalon[ZFA:0000597]." xsd:string {source="ZFA:0000597"} [Term] id: UBERON:0011300 name: gray matter of telencephalon namespace: uberon alt_id: UBERON:0024186 def: "A portion of gray matter that is part of a telencephalon." [OBOL:automatic] synonym: "predominantly gray regional part of telencephalon" EXACT [BIRNLEX:1067] xref: BIRNLEX:1067 xref: FMA:83911 is_a: UBERON:0019264 ! gray matter of forebrain intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0001893 ! telencephalon [Term] id: UBERON:0011332 name: extrinsic tongue pre-muscle mass namespace: uberon xref: EMAPA:17884 is_a: UBERON:0005865 ! pre-muscle condensation intersection_of: UBERON:0005865 ! pre-muscle condensation intersection_of: has_potential_to_develop_into UBERON:0001575 ! extrinsic muscle of tongue relationship: has_potential_to_develop_into UBERON:0001575 ! extrinsic muscle of tongue [Term] id: UBERON:0011362 name: cranial blood vasculature namespace: uberon def: "A blood vasculature that is part of a head." [OBOL:automatic] synonym: "cranial blood vessel" EXACT [ZFA:0005297] synonym: "cranial blood vessels" RELATED PLURAL [TAO:0005297] synonym: "set of blood vessels of head" EXACT [] xref: TAO:0005297 xref: ZFA:0005297 is_a: UBERON:0002200 ! vasculature of head is_a: UBERON:0004537 ! blood vasculature intersection_of: UBERON:0004537 ! blood vasculature intersection_of: part_of UBERON:0000033 ! head property_value: UBPROP:0000001 "Blood vessel part of cranial vasculature.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0005297", ontology="TAO", source="ZFIN:curator"} [Term] id: UBERON:0011369 name: omotransversarius muscle namespace: uberon def: "The omotransversarius is a straplike muscle, which advances and adducts the forelimb, as well as flexes the neck laterally. It covers the transverse processes of the cervical vertebrae, lying to their side. The omotransversarius lies ventral to the trapezius, cranial to the deltoid muscle and is covered cranially by the cleidocervicalis. It extends from the atlas to the spine of the scapula, with its origin on the transverse process of the atlas and its insertion in the distal end of the spine of the scapula. Its name can be split into omo, which is Greek for shoulder, and tranversarius which relates to its attachment to the transverse process of the atlas. This muscle is innervated by the accessory nerve." [MURDOCH:1433] synonym: "omotransverse" EXACT [MA:0002349] synonym: "omotransverse muscle" EXACT [] xref: EMAPA:37690 {source="MA:th"} xref: MA:0002349 xref: NCIT:C52972 xref: UMLS:C1709311 {source="ncithesaurus:Omotransverse"} is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0004651 ! scapula spine intersection_of: attaches_to UBERON:0011370 ! transverse process of atlas relationship: attaches_to UBERON:0004651 ! scapula spine relationship: attaches_to UBERON:0011370 ! transverse process of atlas [Term] id: UBERON:0011370 name: transverse process of atlas namespace: uberon def: "A transverse process of vertebra that is part of a vertebral bone 1." [OBOL:automatic] xref: FMA:23981 xref: SCTID:181895009 xref: Wikipedia:Transverse_processes is_a: UBERON:0001077 ! transverse process of vertebra is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001077 ! transverse process of vertebra intersection_of: part_of UBERON:0001092 ! vertebral bone 1 relationship: in_lateral_side_of UBERON:0001092 {source="FMA-abduced-lr"} ! vertebral bone 1 relationship: part_of UBERON:0001092 ! vertebral bone 1 [Term] id: UBERON:0011565 name: lumen of gastrointestinal system namespace: uberon synonym: "cavity of digestive tract" EXACT [] synonym: "cavity of gastrointestinal tract" EXACT [] synonym: "gastrointestinal tract lumen" EXACT [FMA:54364] synonym: "lumen of gastrointestinal tract" EXACT [FMA:54364] xref: FMA:54364 xref: SCTID:432899004 is_a: UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0001007 ! digestive system [Term] id: UBERON:0011566 name: lumen of esophagus namespace: uberon def: "An anatomical cavity that is part of a esophagus." [OBOL:automatic] subset: pheno_slim synonym: "cavity of eosophagus" EXACT [] synonym: "cavity of esophagus" EXACT [FMA:9398] synonym: "eosophageal cavity" EXACT [] synonym: "eosophageal lumen" EXACT [] synonym: "eosophagus lumen" EXACT [] synonym: "esophageal cavity" EXACT [FMA:9398] synonym: "esophageal lumen" EXACT [FMA:9398] synonym: "esophagus lumen" EXACT [FMA:9398] xref: EMAPA:18380 xref: FMA:9398 xref: SCTID:322648002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001043 ! esophagus relationship: luminal_space_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0011565 {source="FMA"} ! lumen of gastrointestinal system [Term] id: UBERON:0011574 name: mesonephric duct lumen namespace: uberon def: "A tube lumen that is part of a mesonephric duct." [OBOL:automatic] synonym: "cavity of nephric duct" RELATED [] synonym: "nephric duct lumen" EXACT [EHDAA2:0001244] xref: EHDAA2:0001244 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005082 ! tube lumen intersection_of: UBERON:0005082 ! tube lumen intersection_of: luminal_space_of UBERON:0003074 ! mesonephric duct relationship: luminal_space_of UBERON:0003074 ! mesonephric duct relationship: part_of UBERON:0003074 ! mesonephric duct [Term] id: UBERON:0011582 name: paired limb/fin skeleton namespace: uberon def: "The collection of all skeletal elements in an individual limb or fin." [https://orcid.org/0000-0002-6601-2165] subset: homology_grouping synonym: "limb/fin skeleton" EXACT [VSAO:0000301] synonym: "skeletal parts of limb/fin" EXACT [] synonym: "skeleton of limb/fin" EXACT [] xref: VSAO:0000301 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0004708 ! paired limb/fin relationship: develops_from UBERON:0003081 {source="ISBN:9780878932504"} ! lateral plate mesoderm relationship: part_of UBERON:0002091 ! appendicular skeleton relationship: part_of UBERON:0004708 ! paired limb/fin relationship: skeleton_of UBERON:0004708 ! paired limb/fin property_value: UBPROP:0000001 "Skeletal subdivision that is part of the paired limb/fin.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000301", ontology="VSAO", source="GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070"} [Term] id: UBERON:0011583 name: stylopodial skeleton namespace: uberon def: "Proximal element of a free limb skeleton consisting of the femur and humerus in the forelimb stylopodium and hindlimb stylopodium respectively[VSAO, modified]." [VSAO:0005007] synonym: "mesomere 1" RELATED HOMOLOGY [ISBN:0226313409] synonym: "propodial skeleton" RELATED [] synonym: "propodium" RELATED [VSAO:0005007] synonym: "proximal metapterygial mesomere" RELATED HOMOLOGY [ISBN:0226313409] synonym: "stylopod" RELATED [VSAO:0005007] synonym: "stylopodium" RELATED [] synonym: "stylopodium skeleton" EXACT [] xref: VSAO:0005007 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002472 ! stylopod relationship: distally_connected_to UBERON:0011584 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! zeugopodial skeleton relationship: part_of UBERON:0002472 ! stylopod relationship: part_of UBERON:0004381 {source="VSAO"} ! skeleton of limb relationship: skeleton_of UBERON:0002472 ! stylopod property_value: UBPROP:0000001 "Proximal element of the limb skeleton consisting of the femur and humerus in the forelimb stylopodium and hindlimb stylopodium respectively.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0005007", ontology="VSAO", source="VSAO:NI"} property_value: UBPROP:0000007 "propodial" xsd:string property_value: UBPROP:0000007 "stylopodial" xsd:string [Term] id: UBERON:0011584 name: zeugopodial skeleton namespace: uberon def: "Section of the forelimb skeleton located between the stylopodium and the autopodium." [VSAO:0005010] synonym: "epipodial skeleton" EXACT [] synonym: "epipodium" RELATED [VSAO:0005010] synonym: "mesomere 2" RELATED HOMOLOGY [ISBN:0226313409] synonym: "mesomere 2 skeleton" RELATED HOMOLOGY [ISBN:0226313409] synonym: "skeleton of zeugopod" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "zeugopod skeleton" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "zygopodium" RELATED [VSAO:0005010] xref: VSAO:0005010 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0002471 ! zeugopod relationship: distally_connected_to UBERON:0006717 {gci_relation="part_of", gci_filler="NCBITaxon:32523"} ! autopodial skeleton relationship: part_of UBERON:0002471 ! zeugopod relationship: part_of UBERON:0004381 {source="VSAO"} ! skeleton of limb relationship: proximally_connected_to UBERON:0011583 ! stylopodial skeleton relationship: skeleton_of UBERON:0002471 ! zeugopod property_value: UBPROP:0000007 "zeugopodial" xsd:string property_value: UBPROP:0000007 "zygopodial" xsd:string [Term] id: UBERON:0011585 name: cell condensation namespace: uberon def: "Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995)." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000006] xref: VSAO:0000006 xref: XAO:0004021 is_a: UBERON:0000061 {source="VSAO"} ! anatomical structure property_value: editor_note "consider obsoleting, coordinate with VSAO" xsd:string [Term] id: UBERON:0011587 name: pre-dentine namespace: uberon def: "Odontogenic tissue that is collagen-rich and characteristic of vertebrate teeth and tooth-like structures (e.g., odontodes) deposited by preodontoblasts and odontoblasts that are typically excluded from the matrix." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000071] synonym: "pre-dentine tissue" EXACT [VSAO:curator] synonym: "predentin" EXACT [PMCID:PMC3360947] synonym: "predentine tissue" EXACT [VSAO:curator] xref: EMAPA:36439 xref: VSAO:0000071 xref: XAO:0004052 is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue relationship: produced_by CL:0000060 {source="text definition"} ! odontoblast [Term] id: UBERON:0011588 name: pre-enamel namespace: uberon def: "Odontogenic tissue that is avascular non-mineralized matrix that is deposited by preameloblast and ameloblasts that are excluded from the matrix." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000066] synonym: "pre-enamel tissue" EXACT [VSAO:curator] synonym: "preenamel tissue" EXACT [VSAO:curator] xref: VSAO:0000066 xref: XAO:0004202 is_a: UBERON:0010365 {source="VSAO"} ! odontoid tissue relationship: produced_by CL:0000059 ! ameloblast [Term] id: UBERON:0011589 name: non-mineralized cartilage tissue namespace: uberon def: "Cartilage tissue that is not mineralized." [GO_REF:0000034, http://dx.plos.org/10.1371/journal.pone.0051070, PSPUB:0000170, VSAO:0000089] xref: VSAO:0000089 xref: XAO:0004044 is_a: UBERON:0002418 {source="VSAO"} ! cartilage tissue property_value: editor_note "add developmental relationships; add disjointness axiom" xsd:string [Term] id: UBERON:0011592 name: future upper lip namespace: uberon synonym: "upper jaw future lip" EXACT [EHDAA2:0002120] xref: EHDAA2:0002120 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0003235 ! epithelium of upper jaw relationship: develops_from UBERON:0004068 {notes="fusion"} ! medial nasal prominence relationship: develops_from UBERON:0005868 {notes="fusion"} ! maxillary prominence [Term] id: UBERON:0011593 name: maxillary tooth namespace: uberon def: "A tooth that is attached to a maxilla[TAO,modified]." [TAO:0001627] synonym: "maxillary teeth" EXACT PLURAL [AAO:0000287] xref: AAO:0000287 xref: FMA:321646 xref: SCTID:422279005 xref: TAO:0001627 xref: Wikipedia:Tooth_(human) is_a: UBERON:0003267 ! tooth of upper jaw intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0002397 ! maxilla relationship: attaches_to UBERON:0002397 ! maxilla property_value: IAO:0000232 "this ontology also contains a class for 'tooth of upper jaw'. This is not equivalent to 'maxillary tooth' in a multi-species context, because many vertebrates have other tooth-bearing bones in the upper jaw[http://orcid.org/0000-0002-6601-2165]" xsd:string property_value: UBPROP:0000001 "Tooth that is attached to the maxilla.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001627", ontology="TAO", source="TAO:wd"} [Term] id: UBERON:0011594 name: dentary tooth namespace: uberon def: "Tooth that is attached to a dentary/mandible[TAO,modified]." [TAO:0001628] synonym: "mandibular teeth" RELATED PLURAL [AAO:0000641] synonym: "mandibular tooth" RELATED [] synonym: "tooth of dentary" RELATED [] xref: AAO:0000125 xref: AAO:0000641 xref: FMA:321647 xref: SCTID:245547003 xref: TAO:0001628 is_a: UBERON:0003268 ! tooth of lower jaw intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0004742 ! dentary relationship: attaches_to UBERON:0004742 ! dentary property_value: editor_note "Note that we treat dentary tooth and mandibular tooth as equivalent" xsd:string property_value: UBPROP:0000001 "Tooth that is attached to the dentary.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001628", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000002 "relationship loss: part_of dentary tooth row (TAO:0001952)[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001628", ontology="TAO"} [Term] id: UBERON:0011595 name: jaw region namespace: uberon def: "A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:32905 xref: NCIT:C114916 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000475 ! organism subdivision is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0000475 ! organism subdivision intersection_of: has_skeleton UBERON:0001708 ! jaw skeleton relationship: has_skeleton UBERON:0001708 ! jaw skeleton relationship: only_in_taxon NCBITaxon:7776 ! Gnathostomata relationship: part_of UBERON:0000165 {source="EMAPA", source="FMA-abduced", source="ZFA-abduced"} ! mouth property_value: seeAlso "http://eol.org/collections/11578" xsd:anyURI [Term] id: UBERON:0011596 name: future lower lip namespace: uberon synonym: "lower jaw future lip" EXACT [EHDAA2:0001020] xref: EHDAA2:0001020 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0003236 ! epithelium of lower jaw relationship: develops_from UBERON:0005867 {source="Wikipedia:Mandibular_prominence"} ! mandibular prominence [Term] id: UBERON:0011597 name: bone of upper jaw namespace: uberon def: "Any bone that is part of the upper jaw skeleton. This includes (when present): the maxilla, the quadrate (in some species)." [https://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "upper jaw bone" EXACT [] is_a: UBERON:0012360 ! bone of jaw intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0003277 ! skeleton of upper jaw property_value: editor_note "Do not manually classify under here - bones are automatically classified" xsd:string [Term] id: UBERON:0011601 name: gingiva of upper jaw namespace: uberon def: "A gingiva that is part of a upper jaw region." [OBOL:automatic] subset: pheno_slim synonym: "gum of maxilla" EXACT [] synonym: "gum of upper jaw" EXACT [EMAPA:18970] synonym: "maxillary gum" RELATED [FMA:59763] synonym: "upper gingiva" EXACT [] synonym: "upper gum" RELATED [] synonym: "upper jaw gingiva" EXACT [FMA:59763] xref: EMAPA:18970 xref: FMA:59763 xref: NCIT:C54205 xref: SCTID:304703001 xref: UMLS:C0227121 is_a: UBERON:0001828 ! gingiva intersection_of: UBERON:0001828 ! gingiva intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0011602 name: gingiva of lower jaw namespace: uberon def: "A gingiva that is part of a lower jaw region." [OBOL:automatic] subset: pheno_slim synonym: "gum of lower jaw" EXACT [EMAPA:18967] synonym: "gum of mandible" EXACT [] synonym: "lower gingiva" EXACT [] synonym: "lower gum" RELATED [] synonym: "lower jaw gingiva" EXACT [FMA:59764] synonym: "lower jaw gum" RELATED [FMA:59764] synonym: "mandibular gum" RELATED [FMA:59764] xref: EMAPA:18967 xref: FMA:59764 xref: NCIT:C54204 xref: SCTID:304704007 xref: UMLS:C0227123 is_a: UBERON:0001828 ! gingiva intersection_of: UBERON:0001828 ! gingiva intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0011628 name: early premaxilla namespace: uberon synonym: "future premaxilla" EXACT [] xref: EHDAA2:0001495 is_a: UBERON:0008907 ! dermal bone is_a: UBERON:0011597 ! bone of upper jaw relationship: develops_from UBERON:0010334 {source="EHDAA2"} ! maxillary process mesenchyme from neural crest relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0003113 {source="ISBN:0073040584"} ! dermatocranium [Term] id: UBERON:0011641 name: odontogenic mesenchyme of molar namespace: uberon def: "An odontogenic papilla that is part of a molar tooth [Automatically generated definition]." [OBOL:automatic] synonym: "molar mesenchyme" EXACT [https://orcid.org/0000-0002-6601-2165] synonym: "odontogenic mesenchyme of molar tooth" EXACT [OBOL:automatic] xref: EMAPA:32881 xref: MA:0003230 is_a: UBERON:0003856 ! uncondensed odontogenic mesenchyme intersection_of: UBERON:0003856 ! uncondensed odontogenic mesenchyme intersection_of: part_of UBERON:0003655 ! molar tooth relationship: part_of UBERON:0003655 ! molar tooth [Term] id: UBERON:0011642 name: oral epithelium from ectoderm namespace: uberon def: "An epithelium that develops_from a ectoderm and is part of a oral epithelium." [OBOL:automatic] xref: EHDAA2:0004137 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0002424 ! oral epithelium is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_from UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0002424 ! oral epithelium relationship: develops_from UBERON:0009479 {source="EHDAA2"} ! ectoderm of buccopharyngeal membrane relationship: part_of UBERON:0002424 ! oral epithelium [Term] id: UBERON:0011645 name: iliofemoralis muscle namespace: uberon def: "Limb extensor that runs from ilium to femur." [ISBN:0073040584] synonym: "iliofemoralis" EXACT [] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001325 ! muscle of pelvis intersection_of: UBERON:0001325 ! muscle of pelvis intersection_of: has_muscle_insertion UBERON:0000981 ! femur intersection_of: has_muscle_origin UBERON:0001273 ! ilium relationship: has_muscle_insertion UBERON:0000981 ! femur relationship: has_muscle_origin UBERON:0001273 ! ilium [Term] id: UBERON:0011648 name: jaw muscle namespace: uberon subset: efo_slim subset: pheno_slim synonym: "mandibular muscle" EXACT [TAO:0000236] synonym: "mandibular muscles" EXACT PLURAL [TAO:0000236] xref: AAO:0000247 xref: EFO:0003511 xref: TAO:0000236 xref: XAO:0003269 xref: ZFA:0000236 is_a: UBERON:0002376 ! cranial muscle relationship: capable_of_part_of GO:0071626 ! mastication [Term] id: UBERON:0011676 name: subdivision of organism along main body axis namespace: uberon def: "A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column." [https://orcid.org/0000-0002-6601-2165] subset: upper_level synonym: "axial subdivision of organism" EXACT [] synonym: "body segment" RELATED [] synonym: "main body segment" RELATED [] is_a: UBERON:0000475 ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis property_value: editor_note "Ideally this would be disjoint with analagous class for appendicular axes, but currently 'appendages' like antennae, horns cause a problem" xsd:string [Term] id: UBERON:0011677 name: trunk vertebra namespace: uberon def: "A vertebra in the trunk region. For tetrapods, includes lumbar and thoracic vertebrae. Excludes caudal/coccygeal vertebra, which are located posteriorly. In tetrapods this includes thoracic, lumbar and sacral vertebrae, and excludes the cervical vertebrae, which are located anteriorly." [UBERONREF:0000006] subset: pheno_slim synonym: "presacral vertebra" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "thoracolumbar vertebra" EXACT [] is_a: UBERON:0003463 ! trunk bone is_a: UBERON:0004247 ! bone of dorsum is_a: UBERON:0004451 {is_inferred="true"} ! trunk or cervical vertebra intersection_of: UBERON:0002412 ! vertebra intersection_of: part_of UBERON:0009568 ! trunk region of vertebral column relationship: part_of UBERON:0009568 ! trunk region of vertebral column property_value: UBPROP:0000202 FMA:72066 [Term] id: UBERON:0011678 name: hindlimb intermedium bone namespace: uberon def: "A proximal tarsal bone that articulates with the fibula." [http://orcid.org/0000-0002-6601-2165] synonym: "hidlimb intermedium" EXACT [] synonym: "intermedium" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "intermedium (hind)" EXACT [AAO:0000923] synonym: "intermedium of pes" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal intermedium" EXACT [http://orcid.org/0000-0002-6601-2165] xref: AAO:0000923 is_a: UBERON:0011679 ! proximal tarsal bone property_value: UBPROP:0000008 "The amphibian intermedium forms part of the astragalus in amniotes[http://www.science.marshall.edu/okeefef/PDFS/OKeefe_et_al_2006_JMorph.pdf]" xsd:string [Term] id: UBERON:0011679 name: proximal tarsal bone namespace: uberon def: "A tarsal bone that connected_to a hindlimb zeugopod skeleton." [OBOL:automatic] is_a: UBERON:0001447 ! tarsal bone is_a: UBERON:0014395 ! proximal mesopodial bone is_a: UBERON:0015081 ! proximal tarsal endochondral element intersection_of: UBERON:0015081 ! proximal tarsal endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015082 ! proximal tarsal cartilage [Term] id: UBERON:0011693 name: extraembryonic portion of umbilical artery namespace: uberon synonym: "extraembryonic umbilical artery" EXACT [VHOG:0001157] xref: VHOG:0001157 is_a: UBERON:0000478 {source="EHDAA2-abduced"} ! extraembryonic structure is_a: UBERON:0004573 ! systemic artery relationship: branching_part_of UBERON:0001309 {source="FMA"} ! internal iliac artery relationship: part_of UBERON:0001309 ! internal iliac artery relationship: part_of UBERON:0001310 ! umbilical artery relationship: part_of UBERON:0007807 {source="EHDAA2-abduced"} ! connecting stalk vasculature [Term] id: UBERON:0011695 name: embryonic cardiovascular system namespace: uberon def: "A cardiovascular system that is part of a conceptus." [OBOL:automatic] synonym: "conceptus cardiovascular system" EXACT [] synonym: "embryonic circulatory system" RELATED [] synonym: "fetal circulatory system" RELATED [] xref: EHDAA2:0000216 xref: FMA:305965 xref: NCIT:C34148 is_a: UBERON:0004535 ! cardiovascular system intersection_of: UBERON:0004535 ! cardiovascular system intersection_of: part_of UBERON:0004716 ! conceptus relationship: part_of UBERON:0004716 ! conceptus [Term] id: UBERON:0011696 name: left extraembryonic umbilical artery namespace: uberon synonym: "extraembryonic umbilical artery left" EXACT [EHDAA2:0000937] xref: EHDAA2:0000937 is_a: UBERON:0011693 ! extraembryonic portion of umbilical artery relationship: connected_to UBERON:0011695 ! embryonic cardiovascular system [Term] id: UBERON:0011697 name: right extraembryonic umbilical artery namespace: uberon synonym: "extraembryonic umbilical artery right" EXACT [EHDAA2:0001721] xref: EHDAA2:0001721 is_a: UBERON:0011693 ! extraembryonic portion of umbilical artery [Term] id: UBERON:0011757 name: differentiated genital tubercle namespace: uberon synonym: "phallus" RELATED [Wikipedia:Primordial_phallus] synonym: "phallus primordialis" RELATED LATIN [Wikipedia:Primordial_phallus] synonym: "primordial phallus" RELATED [Wikipedia:Primordial_phallus] xref: NCIT:C34274 xref: UMLS:C1514448 {source="ncithesaurus:Primordial_Phallus"} xref: Wikipedia:Primordial_phallus is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure union_of: UBERON:0006233 ! female genital tubercle union_of: UBERON:0006261 ! male genital tubercle relationship: develops_from UBERON:0005876 ! undifferentiated genital tubercle relationship: part_of UBERON:0004176 ! external genitalia [Term] id: UBERON:0011766 name: left recurrent laryngeal nerve namespace: uberon synonym: "left recurrent laryngeal branch" EXACT [EMAPA:25350] synonym: "left recurrent laryngeal nerve" EXACT [FMA:14469] synonym: "vagus X nerve left recurrent laryngeal branch" EXACT [MA:0001107] xref: EMAPA:25350 xref: FMA:14469 xref: MA:0001107 xref: SCTID:280300006 is_a: UBERON:0003716 ! recurrent laryngeal nerve is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0003716 ! recurrent laryngeal nerve intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/6/64/Recurrent_laryngeal_nerve.svg" xsd:anyURI property_value: UBPROP:0000008 "The left nerve is longer than the right, because it crosses under the arch of the aorta at the ligamentum arteriosum.[WP]" xsd:string [Term] id: UBERON:0011767 name: right recurrent laryngeal nerve namespace: uberon synonym: "right recurrent laryngeal branch" EXACT [EMAPA:17275] synonym: "right recurrent laryngeal nerve" EXACT [FMA:14468] synonym: "vagus X nerve right recurrent laryngeal branch" EXACT [MA:0001108] xref: EMAPA:17275 xref: FMA:14468 xref: MA:0001108 xref: SCTID:280299003 is_a: UBERON:0003716 ! recurrent laryngeal nerve is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0003716 ! recurrent laryngeal nerve intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:0011769 name: cartilaginous projection namespace: uberon def: "Anatomical projection that is composed of cartilage tissue." [VSAO:wd] synonym: "cartilage process" EXACT [] synonym: "cartilaginous process" EXACT [] xref: FMA:284626 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004529 ! anatomical projection intersection_of: UBERON:0004529 ! anatomical projection intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0011772 name: lower jaw opening namespace: uberon def: "An anatomical space that is part of a bone of lower jaw." [OBOL:automatic] xref: AAO:0000273 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0004768 ! bone of lower jaw relationship: luminal_space_of UBERON:0004768 ! bone of lower jaw relationship: part_of UBERON:0004768 ! bone of lower jaw [Term] id: UBERON:0011773 name: upper jaw opening namespace: uberon def: "An anatomical space that is part of a bone of upper jaw." [OBOL:automatic] xref: AAO:0000621 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0011597 ! bone of upper jaw relationship: luminal_space_of UBERON:0011597 ! bone of upper jaw relationship: part_of UBERON:0011597 ! bone of upper jaw [Term] id: UBERON:0011775 name: vagus nerve nucleus namespace: uberon def: "A cranial nerve nucleus that is associated with a vagus nerve." [OBOL:automatic] synonym: "nodosal nucleus" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "nucleus of vagal nerve" EXACT [] synonym: "nucleus of vagal X nerve" EXACT [] synonym: "nucleus of vagus nerve" EXACT [FMA:54573] synonym: "nucleus of Xth nerve" EXACT [] synonym: "tenth cranial nerve nucleus" EXACT [FMA:54573] synonym: "vagal nucleus" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "vagal X nucleus" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "vagus nucleus" EXACT [http://orcid.org/0000-0002-6601-2165] xref: FMA:54573 xref: SCTID:362467005 is_a: UBERON:0000126 ! cranial nerve nucleus is_a: UBERON:0009662 ! hindbrain nucleus intersection_of: UBERON:0000126 ! cranial nerve nucleus intersection_of: extends_fibers_into UBERON:0001759 ! vagus nerve relationship: extends_fibers_into UBERON:0001759 ! vagus nerve [Term] id: UBERON:0011777 name: nucleus of spinal cord namespace: uberon def: "A neural nucleus that is part of the spinal cord." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "spinal cord nucleus" EXACT [FMA:77011] xref: FMA:77011 is_a: UBERON:0000125 ! neural nucleus intersection_of: UBERON:0000125 ! neural nucleus intersection_of: part_of UBERON:0002240 ! spinal cord relationship: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0011779 name: nerve of head region namespace: uberon def: "A nerve that is part of a head." [OBOL:automatic] subset: grouping_class synonym: "cephalic nerve" RELATED [] synonym: "head nerve" RELATED [] is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0011814 name: non-neurogenic ectodermal placode namespace: uberon def: "Ectodermal placode that does not develop into a component of the nervous system." [http://orcid.org/0000-0002-6601-2165, PMID:11523831] is_a: UBERON:0005085 {source="cjm"} ! ectodermal placode [Term] id: UBERON:0011820 name: atrioventricular region namespace: uberon def: "An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "atrial ventricular junction" RELATED [GO:0003294] synonym: "atrioventricular junction" RELATED [FMA:85125, GO:0003294] synonym: "atrioventricular segment" RELATED [PMID:21234997] synonym: "AV region" RELATED [PMID:21234997] synonym: "AV segment" RELATED [PMID:21234997] xref: EHDAA2:0004149 xref: FMA:85125 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0002081 ! cardiac atrium intersection_of: connects UBERON:0002082 ! cardiac ventricle intersection_of: part_of UBERON:0000948 ! heart relationship: connects UBERON:0002081 ! cardiac atrium relationship: connects UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0000948 ! heart property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0011821 name: irregular connective tissue namespace: uberon def: "Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium." [FMA:20107] xref: FMA:20107 is_a: UBERON:0002384 {source="FMA"} ! connective tissue [Term] id: UBERON:0011822 name: dense irregular connective tissue namespace: uberon def: "Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium." [FMA:20109, Wikipedia:Dense_irregular_connective_tissue] synonym: "irregular dense connective tissue" EXACT [] synonym: "typus irregularis (textus connectivus collagenosus compactus)" EXACT [FMA:20109] xref: FMA:20109 xref: NCIT:C32882 xref: UMLS:C0738366 {source="ncithesaurus:Irregular_Dense_Connective_Tissue"} xref: Wikipedia:Dense_irregular_connective_tissue is_a: UBERON:0011821 {source="FMA"} ! irregular connective tissue is_a: UBERON:0011823 ! dense connective tissue intersection_of: UBERON:0011821 ! irregular connective tissue intersection_of: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils intersection_of: has_part GO:0071953 ! elastic fiber relationship: has_part GO:0071953 ! elastic fiber property_value: UBPROP:0000001 "Tissue characterized by a thick, random arrangement of collagen and elastin fibers with very few cells. The majority of the cells are fibroblasts, but mast cells and macrophages may also be seen. It is found in the dermis, periosteum, perichondrium, capsules of organs and sheaths of nerves and muscles[NCIT]" xsd:string {date_retrieved="2012-08-29", external_class="ncithesaurus:Irregular_Dense_Connective_Tissue", ontology="NCIT"} [Term] id: UBERON:0011823 name: dense connective tissue namespace: uberon def: "Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets." [Wikipedia:Dense_connective_tissue] xref: AAO:0000121 xref: NCIT:C32450 xref: UMLS:C1511770 {source="ncithesaurus:Dense_Connective_Tissue"} xref: Wikipedia:Dense_connective_tissue is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0002384 ! connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils disjoint_from: UBERON:0011825 ! loose connective tissue relationship: composed_primarily_of UBERON:0011860 ! collection of collagen fibrils property_value: editor_note "our OWL definition states that this is differentiated from other connective tissue types by virtue of the fact that the collage fiber component predominates, as opposed to cells and fluid." xsd:string property_value: UBPROP:0000001 "Connective tissue in which the fibrous component predominates. The cells, ground substance, and tissue fluid represent a minor component[NCIT]" xsd:string {date_retrieved="2012-08-29", external_class="ncithesaurus:Dense_Connective_Tissue", ontology="NCIT"} [Term] id: UBERON:0011824 name: fibrous connective tissue namespace: uberon xref: FMA:75634 xref: SCTID:363130003 is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue [Term] id: UBERON:0011825 name: loose connective tissue namespace: uberon def: "Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue." [FMA:19783] synonym: "textus connectivus collagenosus laxus" EXACT LATIN [FMA:19783, FMA:TA] synonym: "textus connectivus laxus" EXACT LATIN [FMA:19783, FMA:TA] xref: FMA:19783 xref: NCIT:C33007 xref: UMLS:C1253917 {source="ncithesaurus:Loose_Connective_Tissue"} xref: Wikipedia:Loose_connective_tissue is_a: UBERON:0011821 {source="FMA"} ! irregular connective tissue [Term] id: UBERON:0011858 name: acinus of exocrine gland namespace: uberon def: "An acinus that is part of a exocrine gland." [OBOL:automatic] synonym: "exocrine gland acinus" EXACT [] is_a: UBERON:0009842 ! glandular acinus intersection_of: UBERON:0009842 ! glandular acinus intersection_of: part_of UBERON:0002365 ! exocrine gland relationship: part_of UBERON:0002365 ! exocrine gland [Term] id: UBERON:0011860 name: collection of collagen fibrils namespace: uberon xref: FMA:63212 xref: MESH:D024022 xref: NCIT:C32339 xref: NIF_Subcellular:sao7547390221 is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000476 {source="ZFA"} ! acellular anatomical structure relationship: composed_primarily_of GO:0005581 ! collagen trimer relationship: composed_primarily_of GO:0098643 ! banded collagen fibril property_value: seeAlso UBERON:0007377 property_value: UBPROP:0000012 "the FMA class specifically refers to ureter" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0011861 name: aorta collagen fibril namespace: uberon def: "The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011640] subset: pheno_slim is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0011860 ! collection of collagen fibrils intersection_of: UBERON:0011860 ! collection of collagen fibrils intersection_of: part_of UBERON:0004664 ! aorta tunica adventitia relationship: contributes_to_morphology_of UBERON:0004664 ! aorta tunica adventitia relationship: part_of UBERON:0004664 ! aorta tunica adventitia [Term] id: UBERON:0011862 name: pulmonary collagen fibril namespace: uberon def: "The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011641] subset: pheno_slim is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0011860 ! collection of collagen fibrils intersection_of: UBERON:0011860 ! collection of collagen fibrils intersection_of: part_of UBERON:0002048 ! lung relationship: contributes_to_morphology_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0011863 name: bone collagen fibril namespace: uberon def: "The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011642] subset: pheno_slim is_a: UBERON:0011860 ! collection of collagen fibrils intersection_of: UBERON:0011860 ! collection of collagen fibrils intersection_of: part_of UBERON:0001474 ! bone element relationship: part_of UBERON:0001474 ! bone element [Term] id: UBERON:0011864 name: tendon collagen fibril namespace: uberon def: "The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011643] subset: pheno_slim is_a: UBERON:0011860 ! collection of collagen fibrils intersection_of: UBERON:0011860 ! collection of collagen fibrils intersection_of: part_of UBERON:0000043 ! tendon relationship: contributes_to_morphology_of UBERON:0000043 ! tendon relationship: part_of UBERON:0000043 ! tendon [Term] id: UBERON:0011865 name: corneal stroma collagen fibril namespace: uberon def: "The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity." [MP:0011650] subset: pheno_slim is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0011860 ! collection of collagen fibrils intersection_of: UBERON:0011860 ! collection of collagen fibrils intersection_of: part_of UBERON:0001777 ! substantia propria of cornea relationship: contributes_to_morphology_of UBERON:0001777 ! substantia propria of cornea relationship: part_of UBERON:0001777 ! substantia propria of cornea [Term] id: UBERON:0011869 name: pisiform joint namespace: uberon comment: Wikipedia says pisiform and triquetral- todo check pisotriquetral synonym: "articulatio ossis pisiformis" EXACT LATIN [Wikipedia:Pisiform_joint] xref: FMA:73126 xref: Wikipedia:Pisiform_joint is_a: UBERON:0011132 ! intercarpal joint intersection_of: UBERON:0011132 ! intercarpal joint intersection_of: connects UBERON:0001429 ! pisiform intersection_of: connects UBERON:0002445 ! ulnare relationship: connects UBERON:0001429 ! pisiform relationship: connects UBERON:0002445 ! ulnare [Term] id: UBERON:0011871 name: nasomaxillary suture namespace: uberon def: "A cranial suture that connects a nasal bone and connects a maxilla." [OBOL:automatic] synonym: "articulation of the nasal bone with maxilla" RELATED [] synonym: "nasomaxillary suture of skull" EXACT [FMA:52960] xref: FMA:52960 is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0001681 ! nasal bone intersection_of: connects UBERON:0002397 ! maxilla relationship: connects UBERON:0001681 ! nasal bone relationship: connects UBERON:0002397 ! maxilla [Term] id: UBERON:0011875 name: ligament of sternoclavicular joint namespace: uberon def: "A skeletal ligament that is part of a sternoclavicular joint." [OBOL:automatic] synonym: "ligamentum sternoclavicularis" EXACT LATIN [] synonym: "sternoclavicular joint ligament" EXACT [FMA:63980] xref: FMA:63980 xref: SCTID:182386007 is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: part_of UBERON:0001469 ! sternoclavicular joint relationship: part_of UBERON:0001469 ! sternoclavicular joint [Term] id: UBERON:0011878 name: muscle layer of esophagus namespace: uberon def: "A muscle layer that is part of a wall of esophagus." [OBOL:automatic] synonym: "muscle coat of esophagus" EXACT [FMA:62998] synonym: "muscular coat of oesophagus" EXACT [FMA:62998] synonym: "muscular layer of oesophagus" EXACT [FMA:62998] synonym: "tela muscularis (oesophagus)" EXACT LATIN [FMA:62998, FMA:TA] synonym: "tunica muscularis esophagi" EXACT LATIN [] synonym: "tunica muscularis oesophageae" EXACT LATIN [FMA:TA] xref: FMA:62998 is_a: UBERON:0018261 ! muscular coat of digestive tract intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001043 ! esophagus relationship: has_part UBERON:0001134 {notes="upper part", source="Wikipedia:Muscular_layer"} ! skeletal muscle tissue relationship: part_of UBERON:0001096 ! wall of esophagus property_value: UBPROP:0000010 "In the upper esophagus, part of the externa is skeletal muscle, rather than smooth muscle" xsd:string {source="WP"} [Term] id: UBERON:0011892 name: anterior uvea namespace: uberon def: "Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris." [MP:0005194] subset: pheno_slim synonym: "anterior part of uveal tract" EXACT [] synonym: "anterior uveal tract" EXACT [] synonym: "anterior vascular layer of the eyeball" EXACT [] synonym: "anterior vascular tunic of the eye" EXACT [] synonym: "ciliary body and iris" RELATED [] synonym: "Haller tunica vascula" EXACT [MP:0005194] synonym: "tunica vasculosa bulbosa" EXACT [MP:0005194] synonym: "vasculosa oculi" RELATED [MP:0005194] synonym: "ventral uveal tract" EXACT [] xref: EMAPA:37417 {source="MA:th"} xref: SCTID:280656002 is_a: UBERON:0000481 {source="ZFA"} ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure relationship: contributes_to_morphology_of UBERON:0001768 ! uvea relationship: contributes_to_morphology_of UBERON:0001801 ! anterior segment of eyeball relationship: has_part UBERON:0001769 ! iris relationship: has_part UBERON:0001775 ! ciliary body relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001768 {source="MP"} ! uvea [Term] id: UBERON:0011899 name: epimysium namespace: uberon def: "Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous." [Wikipedia:Epimysium] synonym: "epimysia" RELATED PLURAL [Wikipedia:Epimysium] synonym: "fascia of muscle organ" EXACT [FMA:9726] xref: FMA:9726 xref: NCIT:C32527 xref: UMLS:C0504096 {source="ncithesaurus:Epimysium"} xref: Wikipedia:Epimysium is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0011822 {source="FMA"} ! dense irregular connective tissue relationship: bounding_layer_of UBERON:0014892 ! skeletal muscle organ relationship: continuous_with UBERON:0000043 ! tendon relationship: part_of UBERON:0001134 {source="FMA"} ! skeletal muscle tissue property_value: UBPROP:0000009 "The Epimysium also protects muscles from friction against other muscles and bones" xsd:string [Term] id: UBERON:0011919 name: yolk sac blood island namespace: uberon def: "Masses of developing blood cells attached to endothelium in the yolk sac." [MP:0011204] subset: pheno_slim synonym: "visceral yolk sac blood island" EXACT [MP:0011204] synonym: "yolk sac blood islands" EXACT [EHDAA2:0000177] xref: EHDAA2:0000177 xref: EMAPA:16115 is_a: UBERON:0000478 ! extraembryonic structure is_a: UBERON:0003061 ! blood island intersection_of: UBERON:0003061 ! blood island intersection_of: part_of UBERON:0003316 ! mesenchyme of yolk sac relationship: develops_from UBERON:0003316 {source="EHDAA2"} ! mesenchyme of yolk sac relationship: part_of UBERON:0003316 ! mesenchyme of yolk sac [Term] id: UBERON:0011921 name: connecting stalk blood islands namespace: uberon synonym: "blood island of umbilical vesicle" EXACT [Wikipedia:Blood_island] synonym: "insula sanguinea vesiculae umbilicalis" EXACT [Wikipedia:Blood_island] xref: EHDAA2:0003242 is_a: UBERON:0007503 {source="EHDAA2"} ! epithelial vesicle is_a: UBERON:0010303 ! extraembryonic epithelium is_a: UBERON:0012275 ! meso-epithelium relationship: develops_from UBERON:0005667 {source="EHDAA2"} ! connecting stalk mesoderm relationship: part_of UBERON:0002331 {source="EHDAA2"} ! umbilical cord property_value: UBPROP:0000012 "in EHDAA2 gives rise to connecting stalk blood vessels and extraembryonic umbilical vessels" xsd:string {external_ontology="EHDAA2"} [Term] id: UBERON:0011925 name: preganglionic autonomic fiber namespace: uberon def: "Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released." [MESH:A08.663.542.122, Wikipedia:Preganglionic_nerve_fibers] synonym: "preganglionic autonomic fibre" RELATED [] synonym: "preganglionic nerve fiber" EXACT [FMA:5923] xref: FMA:5923 xref: MESH:D001339 xref: NCIT:C12624 xref: Wikipedia:Preganglionic_nerve_fibers is_a: UBERON:0003041 ! trigeminal nerve fibers intersection_of: UBERON:0006134 ! nerve fiber intersection_of: extends_fibers_into UBERON:0001017 ! central nervous system intersection_of: extends_fibers_into UBERON:0001805 ! autonomic ganglion relationship: extends_fibers_into UBERON:0001017 ! central nervous system relationship: extends_fibers_into UBERON:0001805 ! autonomic ganglion relationship: part_of UBERON:0034728 ! autonomic nerve [Term] id: UBERON:0011927 name: preganglionic sympathetic fiber namespace: uberon def: "A cholinergic axonal fiber projecting from the CNS to a sympathetic ganglion." [MP:0008310] synonym: "sympathetic preganglionic fiber" RELATED [MP:0008310] xref: SCTID:323517007 is_a: UBERON:0011925 ! preganglionic autonomic fiber intersection_of: UBERON:0006134 ! nerve fiber intersection_of: extends_fibers_into UBERON:0001017 ! central nervous system intersection_of: extends_fibers_into UBERON:0001806 ! sympathetic ganglion relationship: extends_fibers_into UBERON:0001806 ! sympathetic ganglion relationship: part_of UBERON:0034729 ! sympathetic nerve [Term] id: UBERON:0011930 name: preganglionic parasympathetic fiber namespace: uberon def: "A cholinergic axonal fibers projecting from the CNS to a parasympathetic ganglion." [MP:0008311] synonym: "parasympathetic preganglionic fiber" RELATED [MP:0008311] xref: Wikipedia:Preganglionic_fibers is_a: UBERON:0011925 ! preganglionic autonomic fiber intersection_of: UBERON:0006134 ! nerve fiber intersection_of: extends_fibers_into UBERON:0001017 ! central nervous system intersection_of: extends_fibers_into UBERON:0001808 ! parasympathetic ganglion relationship: extends_fibers_into UBERON:0001808 ! parasympathetic ganglion relationship: part_of UBERON:0004293 ! parasympathetic nerve [Term] id: UBERON:0011953 name: stomach glandular region namespace: uberon def: "A region of the stomach that is lined with glandular epithelium." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "glandular stomach" RELATED [] xref: EMAPA:17623 xref: MA:0001613 xref: NCIT:C77661 xref: SCTID:27633001 xref: UMLS:C0227197 {source="ncithesaurus:Glandular_Stomach"} is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0009870 ! zone of stomach intersection_of: UBERON:0009870 ! zone of stomach intersection_of: has_part UBERON:0006924 ! stomach glandular epithelium relationship: has_part UBERON:0006924 ! stomach glandular epithelium property_value: editor_note "as currently defined, this would include the cardiac antrum; however, the intent may be to exclude the cardiac glands and in mice for this to be part of the region distal to the margo plicatus" xsd:string [Term] id: UBERON:0011955 name: left hepatic vein namespace: uberon def: "A hepatic vein that is part of a left lobe of liver." [OBOL:automatic] subset: human_reference_atlas xref: EMAPA:37164 {source="MA:th"} xref: FMA:14339 xref: MA:0003032 xref: SCTID:55188000 is_a: UBERON:0001143 ! hepatic vein intersection_of: UBERON:0001143 ! hepatic vein intersection_of: part_of UBERON:0001115 ! left lobe of liver relationship: part_of UBERON:0001115 ! left lobe of liver property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0011956 name: right hepatic vein namespace: uberon def: "A hepatic vein that is part of a right lobe of liver." [OBOL:automatic] subset: human_reference_atlas xref: EMAPA:37377 {source="MA:th"} xref: FMA:14338 xref: MA:0003034 xref: SCTID:18135006 is_a: UBERON:0001143 ! hepatic vein intersection_of: UBERON:0001143 ! hepatic vein intersection_of: part_of UBERON:0001114 ! right lobe of liver relationship: part_of UBERON:0001114 ! right lobe of liver property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0011960 name: articular capsule of glenohumeral joint namespace: uberon def: "An articular capsule that is part of the glenohumeral joint." [http://orcid.org/0000-0002-6601-2165] synonym: "articular capsule of humerus" EXACT [Wikipedia:Articular_capsule_of_the_humerus] synonym: "articular capsule of shoulder joint" EXACT [] synonym: "capsule of shoulder joint" EXACT [FMA:34944] synonym: "fibrous capsule of glenohumeral joint" EXACT [FMA:34944] synonym: "glenohumeral joint capsule" RELATED [FMA:34944] xref: FMA:34944 xref: SCTID:361836001 xref: Wikipedia:Articular_capsule_of_the_humerus is_a: UBERON:0001484 ! articular capsule intersection_of: UBERON:0001484 ! articular capsule intersection_of: part_of UBERON:0001470 ! glenohumeral joint relationship: part_of UBERON:0001470 ! glenohumeral joint relationship: surrounds UBERON:0001470 ! glenohumeral joint [Term] id: UBERON:0011961 name: articular capsule of hip joint namespace: uberon def: "An articular capsule that is part of the hip joint." [http://orcid.org/0000-0002-6601-2165] synonym: "capsula articularis coxae" EXACT LATIN [Wikipedia:Capsule_of_hip_joint] synonym: "capsule of hip joint" EXACT [Wikipedia:Capsule_of_hip_joint] synonym: "fibrous capsule of hip joint" EXACT [FMA:42821] xref: FMA:42821 xref: SCTID:263382006 xref: Wikipedia:Capsule_of_hip_joint is_a: UBERON:0001484 ! articular capsule is_a: UBERON:0005179 ! pelvic region element intersection_of: UBERON:0001484 ! articular capsule intersection_of: part_of UBERON:0001486 ! hip joint relationship: part_of UBERON:0001486 ! hip joint relationship: surrounds UBERON:0001486 ! hip joint [Term] id: UBERON:0011962 name: transverse tarsal joint namespace: uberon def: "The transverse tarsal joint is formed by the articulation of the calcaneus with the cuboid, and the articulation of the talus with the navicular. The movement which takes place in this joint is more extensive than that in the other tarsal joints, and consists of a sort of rotation by means of which the foot may be slightly flexed or extended, the sole being at the same time carried medially (inverted) or laterally." [Wikipedia:Transverse_tarsal_joint] synonym: "articulatio tarsi transversa" EXACT [Wikipedia:Transverse_tarsal_joint] synonym: "chopart's joint" EXACT [FMA:35201] synonym: "midtarsal joint" EXACT [Wikipedia:Transverse_tarsal_joint] xref: FMA:35201 xref: NCIT:C102354 xref: SCTID:182220000 xref: Wikipedia:Transverse_tarsal_joint is_a: UBERON:0001487 ! pes joint [Term] id: UBERON:0011963 name: talocalcaneonavicular joint namespace: uberon def: "The talocalcaneonavicular articulation is an arthrodial joint: the rounded head of the talus being received into the concavity formed by the posterior surface of the navicular, the anterior articular surface of the calcaneus, and the upper surface of the plantar calcaneonavicular ligament. There are two ligaments in this joint: the articular capsule and the dorsal talonavicular." [Wikipedia:Talocalcaneonavicular_articulation] synonym: "articulatio talocalcaneonavicularis" EXACT LATIN [Wikipedia:Talocalcaneonavicular_articulation] synonym: "talocalcaneonavicular articulation" EXACT [Wikipedia:Talocalcaneonavicular_articulation] xref: FMA:35204 xref: SCTID:182211009 xref: Wikipedia:Talocalcaneonavicular_articulation is_a: UBERON:0003698 ! subtalar joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001450 ! calcaneus intersection_of: connects UBERON:0001451 ! navicular bone of pes intersection_of: connects UBERON:0002395 ! talus relationship: connects UBERON:0001451 ! navicular bone of pes relationship: part_of UBERON:0011962 {source="FMA-modified"} ! transverse tarsal joint [Term] id: UBERON:0011965 name: saddle joint namespace: uberon def: "In a saddle joint (sellar joint, articulation by reciprocal reception) the opposing surfaces are reciprocally concave-convex." [Wikipedia:Saddle_joint] synonym: "articulation by reciprocal reception" RELATED [Wikipedia:Saddle_joint] synonym: "sellar joint" EXACT [Wikipedia:Saddle_joint] xref: FMA:75298 xref: SCTID:23059003 xref: Wikipedia:Saddle_joint is_a: UBERON:0000982 ! skeletal joint [Term] id: UBERON:0011968 name: radio-carpal joint namespace: uberon def: "A skeletal joint that connects a radius bone and connects a carpal skeleton." [OBOL:automatic] synonym: "articulatio radiocarpea" EXACT LATIN [Wikipedia:Wrist] synonym: "radiocarpal articulation" EXACT [Wikipedia:Wrist] synonym: "radiocarpal joint" EXACT [] synonym: "wrist joint" BROAD INCONSISTENT [FMA:35291] xref: EMAPA:19205 xref: FMA:35291 xref: MA:0000461 xref: SCTID:361839008 is_a: UBERON:0001491 {source="MA"} ! wrist joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0001423 ! radius bone intersection_of: connects UBERON:0009880 ! carpal skeleton relationship: connects UBERON:0001423 ! radius bone [Term] id: UBERON:0011969 name: mesotarsal joint namespace: uberon def: "An ankle joint that passes between the proximal and distal tarsals." [http://palaeos.com/vertebrates/glossary/glossaryM.html] comment: Calcaneus and astragalus are interlocked, line of flexion is distal to them[Kardong] is_a: UBERON:0001487 ! pes joint is_a: UBERON:0011980 ! crurotarsal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0010721 ! distal tarsal bone intersection_of: connects UBERON:0011679 ! proximal tarsal bone relationship: connects UBERON:0010721 ! distal tarsal bone relationship: part_of UBERON:0004454 ! tarsal region [Term] id: UBERON:0011970 name: talofibular ligament namespace: uberon def: "A skeletal ligament that connects the fibula to the talus. Examples: anterior and posterior talofibular ligament." [http://orcid.org/0000-0002-6601-2165] synonym: "ligamentum talofibulare" EXACT LATIN [Wikipedia:Talofibular_ligament] synonym: "talo-fibular ligament" EXACT [] xref: FMA:44080 xref: SCTID:244649001 xref: Wikipedia:Talofibular_ligament is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0001446 ! fibula intersection_of: connects UBERON:0002395 ! talus relationship: connects UBERON:0001446 ! fibula relationship: connects UBERON:0002395 ! talus relationship: connects UBERON:0012291 ! lateral malleolus of fibula relationship: part_of UBERON:0001488 ! ankle joint property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/b/bf/Ankle_en.svg" xsd:anyURI [Term] id: UBERON:0011971 name: calcaneofibular ligament namespace: uberon def: "A skeletal ligament that connects the fibula to the calcaneus." [Wikipedia:Calcaneofibular_ligament] synonym: "ligamentum calcaneofibulare" EXACT LATIN [Wikipedia:Calcaneofibular_ligament] xref: FMA:44089 xref: SCTID:244650001 xref: Wikipedia:Calcaneofibular_ligament is_a: UBERON:0003701 ! calcaneal tendon intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0001446 ! fibula intersection_of: connects UBERON:0001450 ! calcaneus relationship: connects UBERON:0001446 ! fibula relationship: connects UBERON:0012291 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="Wikipedia"} ! lateral malleolus of fibula relationship: part_of UBERON:0001488 ! ankle joint property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/b/bf/Ankle_en.svg" xsd:anyURI property_value: UBPROP:0000008 "In humans, it is a narrow, rounded cord, running from the apex of the fibular malleolus downward and slightly backward to a tubercle on the lateral surface of the calcaneus. It is covered by the tendons of the Peronæi longus and brevis." xsd:string {source="WP,modified"} [Term] id: UBERON:0011972 name: medial ligament of ankle joint namespace: uberon def: "A skeletal ligament that connects a tibia and connects a tarsal skeleton." [OBOL:automatic] synonym: "deltoid collateral ligament of ankle joint" EXACT [FMA:44055] synonym: "deltoid ligament of ankle joint" EXACT [FMA:44055] synonym: "ligamentum collaterale mediale (articulatio talocruralis)" EXACT [FMA:44055] synonym: "ligamentum collaterale mediale articulationis talocruralis" EXACT LATIN [FMA:44055, FMA:TA] synonym: "ligamentum deltoideum" EXACT [FMA:TA] synonym: "ligamentum deltoideum (articulatio talocruralis)" EXACT [FMA:44055] synonym: "medial collateral ligament of ankle joint" EXACT [FMA:44055] xref: FMA:44055 xref: SCTID:41159004 is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0009879 ! tarsal skeleton relationship: connects UBERON:0000979 ! tibia relationship: connects UBERON:0009879 ! tarsal skeleton relationship: part_of UBERON:0001488 ! ankle joint [Term] id: UBERON:0011973 name: epiphysis of phalanx of pes namespace: uberon def: "An epiphysis that is part of a phalanx of a pes [Automatically generated definition]." [OBOL:automatic] synonym: "epiphysis of phalanx of toe" EXACT [] xref: SCTID:314621001 is_a: UBERON:0001437 ! epiphysis intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0002387 ! pes [Term] id: UBERON:0011974 name: epiphysis of proximal phalanx of pes namespace: uberon def: "An epiphysis that is part of a proximal phalanx of pes." [OBOL:automatic] synonym: "epiphysis of proximal phalanx of toe" EXACT [] xref: SCTID:280047006 is_a: UBERON:0004446 ! epiphysis of phalanx is_a: UBERON:0011973 ! epiphysis of phalanx of pes intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003868 ! proximal phalanx of pes relationship: part_of UBERON:0003868 ! proximal phalanx of pes [Term] id: UBERON:0011975 name: epiphysis of middle phalanx of pes namespace: uberon def: "An epiphysis that is part of a middle phalanx of pes." [OBOL:automatic] synonym: "epiphysis of middle phalanx of toe" EXACT [] xref: SCTID:280048001 is_a: UBERON:0004446 ! epiphysis of phalanx is_a: UBERON:0011973 ! epiphysis of phalanx of pes intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003866 ! middle phalanx of pes relationship: part_of UBERON:0003866 ! middle phalanx of pes [Term] id: UBERON:0011976 name: epiphysis of distal phalanx of pes namespace: uberon def: "An epiphysis that is part of a distal phalanx of pes." [OBOL:automatic] synonym: "epiphysis of distal phalanx of toe" EXACT [] xref: SCTID:280049009 is_a: UBERON:0004446 ! epiphysis of phalanx is_a: UBERON:0011973 ! epiphysis of phalanx of pes intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003867 ! distal phalanx of pes relationship: part_of UBERON:0003867 ! distal phalanx of pes [Term] id: UBERON:0011977 name: epiphysis of proximal phalanx of manus namespace: uberon def: "An epiphysis that is part of a proximal phalanx of manus." [OBOL:automatic] subset: pheno_slim synonym: "epiphysis of proximal phalanx of finger" EXACT [] xref: SCTID:280044004 is_a: UBERON:0004387 ! epiphysis of phalanx of manus intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0002234 ! proximal phalanx of manus relationship: part_of UBERON:0002234 ! proximal phalanx of manus [Term] id: UBERON:0011978 name: epiphysis of middle phalanx of manus namespace: uberon def: "An epiphysis that is part of a middle phalanx of manus." [OBOL:automatic] synonym: "epiphysis of middle phalanx of finger" EXACT [] xref: SCTID:280045003 is_a: UBERON:0004387 ! epiphysis of phalanx of manus intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003864 ! middle phalanx of manus relationship: part_of UBERON:0003864 ! middle phalanx of manus [Term] id: UBERON:0011979 name: epiphysis of distal phalanx of manus namespace: uberon def: "An epiphysis that is part of a distal phalanx of manus." [OBOL:automatic] synonym: "epiphysis of distal phalanx of finger" EXACT [] xref: FMA:321561 xref: SCTID:280046002 is_a: UBERON:0004387 ! epiphysis of phalanx of manus intersection_of: UBERON:0001437 ! epiphysis intersection_of: part_of UBERON:0003865 ! distal phalanx of manus relationship: part_of UBERON:0003865 ! distal phalanx of manus [Term] id: UBERON:0011980 name: crurotarsal joint namespace: uberon def: "A joint that connects the bones of the crus to the proximal tarsal bones." [Wikipedia:Crurotarsal] comment: line of flexion between calcaneus and astragalus synonym: "crurotarsal" RELATED [] xref: Wikipedia:Crurotarsal is_a: UBERON:0001488 ! ankle joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0010720 ! hindlimb zeugopod skeleton intersection_of: connects UBERON:0011679 ! proximal tarsal bone relationship: connects UBERON:0011679 ! proximal tarsal bone property_value: UBPROP:0000001 "an ankle joint that passes between the astragalus and calcaneum[Palaeos]." xsd:string {source="http://palaeos.com/vertebrates/glossary/glossaryCr.html#Crurotarsal%20joint"} [Term] id: UBERON:0011997 name: coelom namespace: uberon def: "The aggregate of the coelemic cavity lumen plus the membranes that line the lumen." [UBERON:cjm, Wikipedia:Body_cavity, Wikipedia:Coelom] synonym: "coelem" RELATED [] synonym: "coelomic cavity" RELATED [EHDAA2:0004731] synonym: "enterocoelom" NARROW [NCBITaxon:33511] synonym: "haemocoelom" NARROW [] synonym: "schizocoelom" NARROW [] xref: EHDAA2:0004731 xref: Wikipedia:Coelom is_a: UBERON:0000481 {source="EHDAA2"} ! multi-tissue structure relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of NCBITaxon:6072 ! Eumetazoa property_value: editor_note "EHDAA2 distingsuishes between the lumen, the lining, and the 'coelomic cavity', which despire it's name, is not a space - it is the aggregate of space plus lining." xsd:string property_value: RO:0002161 NCBITaxon:147099 {source="Wikipedia:Acoelomorpha"} property_value: UBPROP:0000007 "coelomic" xsd:string [Term] id: UBERON:0012054 name: myocoele namespace: uberon def: "The cavity within a myotome." [http://medical-dictionary.thefreedictionary.com/myocoele] xref: EMAPA:31134 xref: VHOG:0001283 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0003082 ! myotome relationship: luminal_space_of UBERON:0003082 ! myotome relationship: part_of UBERON:0003082 ! myotome property_value: UBPROP:0000003 "The central cavity within the mesoderm is the paired primary or embryonic coelom. Parts of the embryonic coelom often become enclosed in the mesoderm, forming a myocoel within the epimere, a nephrocoel within the mesomere, and simple coelom (body cavity) within the lateral plate mesoderm.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001283", ontology="VHOG", source="ISBN:978-0072528305 Kardong KV, Vertebrates: Comparative Anatomy, Function, Evolution (2006) p.166 and Figure 5.6", source="http://bgee.unil.ch/"} [Term] id: UBERON:0012070 name: palatal tooth namespace: uberon def: "A tooth that is on the roof of the mouth." [http://palaeos.com/vertebrates/therapsida/anteosauria.html] synonym: "palatal teeth" EXACT PLURAL [] is_a: UBERON:0003267 ! tooth of upper jaw intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0012071 ! palate bone relationship: attaches_to UBERON:0012071 ! palate bone [Term] id: UBERON:0012071 name: palate bone namespace: uberon def: "Any bone that is part of a palate." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "palatal bone" EXACT [] xref: EMAPA:37930 {source="MA:th"} xref: NCIT:C33248 xref: UMLS:C1518857 {source="ncithesaurus:Palate_Bone"} is_a: UBERON:0003457 ! head bone is_a: UBERON:0008907 ! dermal bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0007375 ! roof of mouth relationship: part_of UBERON:0012072 ! palatal part of dermatocranium property_value: IAO:0000232 "this is distinct (but not disjoint) from palatine bone" xsd:string [Term] id: UBERON:0012072 name: palatal part of dermatocranium namespace: uberon synonym: "dermatocranium, palatal series" RELATED [ISBN:0073040584] synonym: "palatal series" RELATED [ISBN:0073040584] is_a: UBERON:0000075 ! subdivision of skeletal system relationship: part_of UBERON:0003113 ! dermatocranium relationship: part_of UBERON:0007375 ! roof of mouth [Term] id: UBERON:0012073 name: tooth of palatine bone namespace: uberon def: "A tooth that is attached to a palatine bone." [https://orcid.org/0000-0002-6601-2165] synonym: "palatine teeth" EXACT PLURAL [] synonym: "palatine tooth" EXACT [] is_a: UBERON:0012070 ! palatal tooth intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0001682 ! palatine bone relationship: attaches_to UBERON:0001682 ! palatine bone property_value: UBPROP:0000001 "Teeth present in some fishes on the palatine bones, bones that lie inside the upper jaw bones (sometimes maxillaries, sometimes premaxillaries) usually behind the vomerine tooth patch." xsd:string {source="http://www.fishbase.org/glossary/Glossary.php?q=palatine+teeth"} [Term] id: UBERON:0012074 name: bony part of hard palate namespace: uberon def: "A subdivision of skeletal system that subdivision_of a hard palate." [OBOL:automatic] subset: pheno_slim synonym: "bony palate" EXACT [FMA:59857] synonym: "hard palate skeleton" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "palatum osseum" EXACT [FMA:TA] xref: EMAPA:37444 {source="MA:th"} xref: FMA:59857 is_a: UBERON:0000075 ! subdivision of skeletal system is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0000075 ! subdivision of skeletal system intersection_of: subdivision_of UBERON:0003216 ! hard palate relationship: part_of UBERON:0003216 {source="FMA"} ! hard palate relationship: part_of UBERON:0012072 ! palatal part of dermatocranium relationship: subdivision_of UBERON:0003216 ! hard palate [Term] id: UBERON:0012075 name: replacement bone namespace: uberon def: "Bone that forms as a replacement of another structural tissue." [ZFA:0001628] synonym: "replacement bones" EXACT PLURAL [ZFA:0001628] xref: AAO:0010768 xref: TAO:0001637 xref: ZFA:0001628 is_a: UBERON:0001474 {source="ZFA"} ! bone element is_a: UBERON:0010522 {source="ZFA"} ! replacement element property_value: UBPROP:0000001 "Bone that forms as a replacement of another structural tissue.[TAO]" xsd:string {date_retrieved="2012-08-14", external_class="TAO:0001637", ontology="TAO", source="TAO:wd"} property_value: UBPROP:0000012 "This class was introduced to be consistent with the ZFA hierarchy. The corresponding TAO term was obsoleted, and never introduced into VSAO. Note that VSAO does have replacement element." xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0012076 name: tibiotalar joint namespace: uberon def: "A skeletal joint that connects a tibia and connects a talus." [OBOL:automatic] synonym: "ankle joint" BROAD [Wikipedia:Ankle] synonym: "talotibial joint" NARROW [Wikipedia:Ankle] synonym: "tibioastragalar joint" NARROW [Wikipedia:Ankle] xref: SCTID:361864006 is_a: UBERON:0011980 ! crurotarsal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0000979 ! tibia intersection_of: connects UBERON:0002395 ! talus relationship: connects UBERON:0000979 ! tibia relationship: connects UBERON:0002395 ! talus property_value: UBPROP:0000012 "see also FMA:44063 ! tibiotalar part of medial ligament of ankle joint" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0012080 name: patella cartilage element namespace: uberon def: "A cartilaginous condensation that has the potential to develop into a patella." [OBOL:automatic] xref: EMAPA:19140 is_a: UBERON:0003860 ! hindlimb mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005863 ! cartilaginous condensation intersection_of: UBERON:0005863 ! cartilaginous condensation intersection_of: has_potential_to_develop_into UBERON:0002446 ! patella relationship: adjacent_to UBERON:0001485 ! knee joint relationship: develops_from UBERON:0012081 ! patella pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0002446 ! patella relationship: part_of UBERON:0001441 ! hindlimb skeleton property_value: editor_note "Note some sources have this as intramembranous" xsd:string [Term] id: UBERON:0012081 name: patella pre-cartilage condensation namespace: uberon def: "A pre-cartilage condensation that has the potential to develop into a patella." [OBOL:automatic] xref: EMAPA:18510 is_a: UBERON:0003321 ! mesenchyme of knee is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005866 ! pre-cartilage condensation intersection_of: UBERON:0005866 ! pre-cartilage condensation intersection_of: has_potential_to_develop_into UBERON:0002446 ! patella relationship: has_potential_to_develop_into UBERON:0002446 ! patella relationship: part_of UBERON:0001441 ! hindlimb skeleton relationship: part_of UBERON:0006256 {source="EMAPA"} ! knee joint primordium [Term] id: UBERON:0012082 name: bronchial lumen namespace: uberon def: "An anatomical cavity that is part of a bronchus." [OBOL:automatic] synonym: "bronchial lumen" EXACT [FMA:62646] synonym: "lumen of bronchus" EXACT [FMA:62646] xref: FMA:62646 xref: SCTID:199401001 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 {source="FMA"} ! anatomical space intersection_of: luminal_space_of UBERON:0002185 {source="FMA"} ! bronchus relationship: luminal_space_of UBERON:0002185 ! bronchus relationship: part_of UBERON:0002185 {source="FMA"} ! bronchus [Term] id: UBERON:0012111 name: diastema namespace: uberon alt_id: UBERON:0013134 def: "A space or gap between two teeth." [UBERON:cjm, Wikipedia:Diastema_(dentistry)] comment: Some animals, like horses, that have diastema between incisors and premolars because canines were evolutionarily loss, sometimes have a vestigial canine in the diastema, but the diastema is still considered between the incisor and premolar. synonym: "diastemata" RELATED PLURAL [] synonym: "interdental space" EXACT [] xref: FMA:77271 xref: MESH:D003970 xref: SCTID:410003009 xref: Wikipedia:Diastema_(dentistry) is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space relationship: adjacent_to UBERON:0001091 ! calcareous tooth relationship: adjacent_to UBERON:0001091 {cardinality="2"} ! calcareous tooth relationship: part_of UBERON:0001708 ! jaw skeleton relationship: part_of UBERON:0003672 ! dentition property_value: UBPROP:0000008 "Many species of mammals have diastemata as a normal feature, most commonly between the incisors and molars" xsd:string [Term] id: UBERON:0012125 name: dermatological-muscosal system namespace: uberon def: "Anatomical system that consists of the integumental system plus all mucosae and submucosae." [https://github.com/obophenotype/uberon/issues/53] synonym: "dermatological system" RELATED [OBI:MC] is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0000467 ! anatomical system relationship: existence_ends_during UBERON:0000066 ! fully formed stage relationship: has_part UBERON:0000009 ! submucosa relationship: has_part UBERON:0000344 ! mucosa relationship: has_part UBERON:0002072 ! hypodermis relationship: has_part UBERON:0002097 ! skin of body relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mcourtot [Term] id: UBERON:0012126 name: fibulare namespace: uberon def: "One of two elements that constitute the basal row of tarsals. The fibulare constitutes the preaxial element[AAO]." [AAO:0000913] synonym: "astragalus" RELATED [AAO:0000913] xref: AAO:0000913 is_a: UBERON:0011679 ! proximal tarsal bone relationship: preaxialmost_part_of UBERON:0009879 ! tarsal skeleton property_value: UBPROP:0000001 "One of two element that constitute the basal row of tarsals. The fibulare constitutes the preaxial element. In salamanders this element is aproximatelly rounded, whereas in anurans it is an elongate, cylindrical bone with the proximal and distal heads fused to the heads of the tibiale.[AAO]" xsd:string {date_retrieved="2012-06-20", external_class="AAO:0000913", ontology="AAO", source="AAO:LAP"} property_value: UBPROP:0000008 "In salamanders this element is aproximatelly rounded, whereas in anurans it is an elongate, cylindrical bone with the proximal and distal heads fused to the heads of the tibiale" xsd:string {source="AAO"} [Term] id: UBERON:0012128 name: nose tip namespace: uberon def: "Outermost point on an external nose or snout." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/109] subset: pheno_slim synonym: "apex nasi" EXACT LATIN [FMA:TA] synonym: "apex of nose" EXACT [FMA:59518] synonym: "nasal tip" EXACT [FMA:59518] synonym: "pirula" RELATED [https://www.abdn.ac.uk/bestiary/translat/84v.hti] synonym: "snout tip" RELATED [] synonym: "tip of nose" EXACT [FMA:59518] synonym: "tip of snout" RELATED [] xref: EMAPA:37915 {source="MA:th"} xref: FMA:59518 xref: SCTID:361926005 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: part_of UBERON:0007827 {source="FMA"} ! external nose [Term] id: UBERON:0012131 name: centrale namespace: uberon def: "Endochondral bone located between the proximal and distal rows of carpals or tarsals and thus representing the central carpals or tarsals[PHENOSCAPE]." [https://github.com/obophenotype/uberon/issues/124, PHENOSCAPE:AMAO] synonym: "central mesopodium bone" EXACT [] synonym: "centralia" RELATED PLURAL [] synonym: "os centrale" EXACT [FMA:77232] xref: EMAPA:36170 xref: FMA:77232 is_a: UBERON:0003656 ! mesopodium bone is_a: UBERON:0015067 ! centrale endochondral element intersection_of: UBERON:0015067 ! centrale endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0015077 ! centrale cartilage relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/alex-dececchi relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall property_value: IAO:0000232 "This term corresponds both to the navicular bone in the pes and the similar central carpals in the manus" xsd:string property_value: UBPROP:0000012 "the FMA term is under 'general anatomical term'." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0012139 name: segment of autopod namespace: uberon is_a: UBERON:0002529 {notes="may be revised"} ! limb segment relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0012140 name: digitopodium region namespace: uberon def: "A segment of the autopod consisting of both acropodial region and metapodial region, but excluding the mesopodial/basopodial region." [https://github.com/obophenotype/uberon/issues/131, PHENOSCAPE:ni] synonym: "acropodium (Wagner)" RELATED [] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0012139 ! segment of autopod intersection_of: UBERON:0012139 ! segment of autopod intersection_of: has_skeleton UBERON:0012150 ! skeleton of digitopodium relationship: adjacent_to UBERON:0006716 ! mesopodium region relationship: has_skeleton UBERON:0012150 ! skeleton of digitopodium property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:anyURI property_value: UBPROP:0000013 "some sources call this the acropodium. see https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:string [Term] id: UBERON:0012141 name: manual digitopodium region namespace: uberon def: "A digitopodium region that is part of a manus[Obol]. This includes the fingers and metacarpal region, but excludes the carpal region." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0005451 ! segment of manus is_a: UBERON:0012140 ! digitopodium region intersection_of: UBERON:0012140 ! digitopodium region intersection_of: part_of UBERON:0002398 ! manus relationship: has_skeleton UBERON:0012151 ! skeleton of manual digitopodium property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:anyURI property_value: UBPROP:0000013 "some sources call this the acropodium. see https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:string [Term] id: UBERON:0012142 name: pedal digitopodium region namespace: uberon def: "A digitopodium region that is part of a pes[Obol]. This includes the toes and metatarsal region, but excludes the tarsals region." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0005445 ! segment of pes is_a: UBERON:0012140 ! digitopodium region intersection_of: UBERON:0012140 ! digitopodium region intersection_of: part_of UBERON:0002387 ! pes relationship: has_skeleton UBERON:0012152 ! skeleton of pedal digitopodium property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:anyURI property_value: UBPROP:0000013 "some sources call this the acropodium. see https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:string [Term] id: UBERON:0012150 name: skeleton of digitopodium namespace: uberon def: "A subdivision of the autopod skeleton consisting of both acropodial skeleon and metapodial skeleton, but excluding the mesopodial/basopodial skeleton." [PHENOSCAPE:ni] synonym: "digitopodium" RELATED [PHENOSCAPE:ni] synonym: "skeleton of digits" RELATED COMPARATIVE_PREFERRED [] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0012140 ! digitopodium region relationship: part_of UBERON:0006717 ! autopodial skeleton relationship: part_of UBERON:0012140 ! digitopodium region relationship: skeleton_of UBERON:0012140 ! digitopodium region property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:anyURI property_value: UBPROP:0000013 "some sources call this the acropodium. see https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:string [Term] id: UBERON:0012151 name: skeleton of manual digitopodium namespace: uberon def: "A subdivision of the manus skeleton consisting of both manual acropodial skeleton and metacarpal skeleton, but excluding the carpal skeleton." [https://orcid.org/0000-0002-6601-2165, PHENOSCAPE:ni] synonym: "manual digitopodium" RELATED [] is_a: UBERON:0012150 ! skeleton of digitopodium intersection_of: UBERON:0012150 ! skeleton of digitopodium intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0001442 ! skeleton of manus relationship: part_of UBERON:0012141 {source="FMA"} ! manual digitopodium region property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:anyURI property_value: UBPROP:0000013 "some sources call this the acropodium. see https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:string [Term] id: UBERON:0012152 name: skeleton of pedal digitopodium namespace: uberon def: "A subdivision of the pes skeleton consisting of both pedal acropodial skeleton and metatarsal skeleton, but excluding the tarsal skeleton." [https://orcid.org/0000-0002-6601-2165, PHENOSCAPE:ni] synonym: "pedal digitopodium" RELATED [] is_a: UBERON:0012150 ! skeleton of digitopodium intersection_of: UBERON:0012150 ! skeleton of digitopodium intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0001445 ! skeleton of pes relationship: part_of UBERON:0012142 ! pedal digitopodium region property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:anyURI property_value: UBPROP:0000013 "some sources call this the acropodium. see https://github.com/obophenotype/uberon/wiki/Subdivisions-of-the-autopod" xsd:string [Term] id: UBERON:0012168 name: umbilical cord blood namespace: uberon def: "Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]." [Wikipedia:Cord_blood] comment: Cord blood is collected because it contains stem cells, which can be used to treat hematopoietic and genetic disorders.[WP] subset: efo_slim synonym: "cord blood" RELATED [BTO:0004053] synonym: "fetal blood" RELATED [MESH:A12.207.152.200] synonym: "umbilical cord blood" RELATED [MESH:A12.207.152.200] xref: BTO:0004053 xref: CALOHA:TS-1079 xref: EFO:0001942 xref: MESH:D005312 xref: Wikipedia:Cord_blood is_a: UBERON:0013755 ! arterial blood intersection_of: UBERON:0000178 ! blood intersection_of: located_in UBERON:0001310 ! umbilical artery relationship: located_in UBERON:0001310 ! umbilical artery relationship: part_of UBERON:0000323 ! late embryo [Term] id: UBERON:0012172 name: stomach primordium namespace: uberon def: "A primordium that has the potential to develop into a stomach." [OBOL:automatic] subset: efo_slim synonym: "stomach endoderm" RELATED [EFO:0002580] xref: EFO:0002580 xref: NCIT:C34305 xref: UMLS:C1514976 {source="ncithesaurus:Stomach_Primordium"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0000945 ! stomach relationship: has_potential_to_develop_into UBERON:0000945 ! stomach relationship: part_of UBERON:0003258 ! endoderm of foregut [Term] id: UBERON:0012175 name: acoustico-facial VII-VIII ganglion complex namespace: uberon synonym: "acousticofacial ganglion" EXACT [] synonym: "facio-acoustic ganglion" EXACT [] synonym: "facio-acoustic ganglion complex" RELATED [EMAPA:16794] synonym: "facio-acoustic ganglion complex VII-VIII" EXACT [EMAPA:16794] synonym: "facio-acoustic VII-VIII ganglion complex" RELATED [VHOG:0000715] xref: EHDAA2:0000494 xref: EMAPA:16794 xref: SCTID:361514006 xref: VHOG:0000715 is_a: UBERON:0001714 {source="cjm"} ! cranial ganglion is_a: UBERON:0010313 ! neural crest-derived structure relationship: develops_from UBERON:0003051 {source="EHDAA2"} ! ear vesicle relationship: develops_from UBERON:0006232 {source="cjm"} ! facio-acoustic VII-VIII preganglion complex [Term] id: UBERON:0012180 name: head or neck skin namespace: uberon def: "A zone of skin that is part of a craniocervical region." [OBOL:automatic] xref: EMAPA:37276 {source="MA:th"} xref: MA:0000574 xref: NCIT:C12294 xref: UMLS:C1522650 {source="ncithesaurus:Skin_of_the_Scalp_and_Neck"} is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0007811 ! craniocervical region relationship: part_of UBERON:0007811 ! craniocervical region [Term] id: UBERON:0012193 name: phrenic vein namespace: uberon def: "The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins." [ncithesaurus:Phrenic_Vein] xref: EMAPA:37180 {source="MA:th"} xref: MA:0002194 xref: NCIT:C53062 xref: UMLS:C1709532 {source="ncithesaurus:Phrenic_Vein"} is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001103 ! diaphragm relationship: drains UBERON:0001103 ! diaphragm relationship: part_of RO:0002577 ! system [Term] id: UBERON:0012239 name: urinary bladder vasculature namespace: uberon def: "Network of tubes that carries blood through the distensible musculomembranous organ that serves to collect and store urine excreted by the kidneys[MP]." [MP:MP] subset: human_reference_atlas subset: pheno_slim synonym: "bladder vasculature" EXACT [] synonym: "blood vessel of bladder" RELATED [EMAPA:28679] synonym: "blood vessels of bladder" EXACT [EMAPA:28679] synonym: "set of urinary bladder blood vessels" EXACT [] xref: EMAPA:28679 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 {source="EMAPA"} ! vasculature intersection_of: part_of UBERON:0001255 {source="EMAPA"} ! urinary bladder relationship: contributes_to_morphology_of UBERON:0001255 ! urinary bladder relationship: part_of UBERON:0001255 ! urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012240 name: urethral meatus namespace: uberon def: "External opening or orifice of the urethra through which urine and seminal fluid (in males only) leave the body; in males the meatus presents as a vertical slit normally positioned at the tip of glans penis; in females the meatus is located between the clitoris and the vagina in the vulvular vestibule of the female genitalia[MP]." [MP:MP, Wikipedia:Urinary_meatus] subset: pheno_slim synonym: "external meatus of urethra" EXACT [FMA:19650] synonym: "external urethral orifice" EXACT [FMA:19650] synonym: "external urethral ostium" EXACT [FMA:19650] synonym: "external urinary meatus" EXACT [FMA:19650] synonym: "meatus urinarius" EXACT LATIN [] synonym: "orificium urethrae externum" EXACT LATIN [] synonym: "orificium urethræ externum" EXACT LATIN [] synonym: "urethral meatus" EXACT [FMA:19650] synonym: "urinary meatus" RELATED [] xref: EMAPA:37977 {source="MA:th"} xref: FMA:19650 xref: SCTID:181424008 xref: Wikipedia:Urinary_meatus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010418 ! urethral opening intersection_of: UBERON:0000161 ! orifice intersection_of: connects UBERON:0010390 ! lumen of urethra intersection_of: connects UBERON:0013514 ! space surrounding organism intersection_of: part_of UBERON:0000057 ! urethra relationship: connects UBERON:0010390 ! lumen of urethra relationship: connects UBERON:0013514 ! space surrounding organism relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0012241 name: male urethral meatus namespace: uberon def: "A urethral meatus that is part of a male urethra[Automatically generated definition]." [OBOL:automatic, Wikipedia:External_urethral_orifice_(male)] synonym: "distal urethral opening of male" RELATED [EMAPA:36434] synonym: "external orifice of male urethra" EXACT [FMA:85265] synonym: "external urethral orifice (male)" EXACT [FMA:85265] synonym: "male urethra ostium" EXACT [MA:0002642] synonym: "ostium urethrae externum (urethra masculina)" EXACT LATIN [FMA:TA] synonym: "urethral meatus of penile urethra" EXACT [EMAPA:36434] synonym: "urethral opening of penile urethra" RELATED [EMAPA:36434] xref: EMAPA:36434 xref: FMA:85265 xref: MA:0002642 xref: SCTID:279478000 xref: Wikipedia:External_urethral_orifice_(male) is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0012240 ! urethral meatus intersection_of: UBERON:0012240 ! urethral meatus intersection_of: part_of UBERON:0003101 ! male organism relationship: part_of UBERON:0001299 ! glans penis relationship: part_of UBERON:0001333 ! male urethra property_value: UBPROP:0000001 "The external urethral orifice is the external opening or meatus of the urethra, normally placed at the tip of glans penis; it presents as a vertical slit, possibly bounded on either side by two small labia-like projections, In some cases the slit may be more rounded. This occurs naturally in some males and may also be a side effect of excess skin removal during circumcision. Congenital misplacement of the urethral orifice is called hypospadias when it is located in the underside (ventral aspect) of the penis, and epispadias when located in the dorsum (upper aspect). Improper shaping of the meatus can result in meatal stenosis." xsd:string {source="Wikipedia:External_urethral_orifice_(male)"} [Term] id: UBERON:0012242 name: internal urethral orifice namespace: uberon def: "The usually crescent-shaped opening of the urinary bladder into the urethra, placed at the anteroinferior angle (apex) of the urinary bladder trigone." [MGI:anna, MP:0011782] subset: pheno_slim synonym: "internal meatus of urethra" EXACT [FMA:85263] synonym: "internal urethral orifice of urinary bladder" EXACT [FMA:85263] synonym: "internal urethral ostium" EXACT [FMA:85263] synonym: "internal urethral ostium" RELATED [MP:0011782] synonym: "internal urinary meatus" RELATED [MP:0011782] synonym: "orificium urethrae internum" EXACT LATIN [MP:0011782] synonym: "ostium orificium internum" EXACT LATIN [] synonym: "ostium urethrae internum" EXACT LATIN [Wikipedia:Internal_urethral_orifice] synonym: "vesicourethral orifice" EXACT [FMA:85263] xref: FMA:85263 xref: SCTID:362228001 xref: Wikipedia:Internal_urethral_orifice is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010418 ! urethral opening intersection_of: UBERON:0000161 ! orifice intersection_of: connects UBERON:0009958 ! bladder lumen intersection_of: connects UBERON:0010390 ! lumen of urethra intersection_of: part_of UBERON:0000057 ! urethra relationship: connects UBERON:0009958 ! bladder lumen relationship: connects UBERON:0010390 ! lumen of urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0012254 name: abdominal aorta artery namespace: uberon def: "An artery that originates from the abdominal aorta." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Abdominal_aorta#Branches] subset: pheno_slim synonym: "abdominal artery" EXACT [] synonym: "artery of abdomen" EXACT [] xref: SCTID:281470000 is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: branching_part_of UBERON:0001516 ! abdominal aorta relationship: branching_part_of UBERON:0001516 ! abdominal aorta relationship: part_of UBERON:0001516 ! abdominal aorta [Term] id: UBERON:0012274 name: columnar epithelium namespace: uberon def: "An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified]." [Wikipedia:Columnar_epithelium] xref: Wikipedia:Columnar_epithelium is_a: UBERON:0000483 ! epithelium relationship: has_part CL:0000075 ! columnar/cuboidal epithelial cell [Term] id: UBERON:0012275 name: meso-epithelium namespace: uberon def: "Epithelium that derives from the mesoderm. [Automatically generated definition]." [OBOL:automatic] synonym: "mesoderm-derived epithelium" EXACT [] synonym: "mesoepithelium" EXACT [] xref: FMA:86452 is_a: UBERON:0000483 ! epithelium is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000483 ! epithelium intersection_of: develops_from UBERON:0000926 ! mesoderm [Term] id: UBERON:0012276 name: endometrium glandular epithelium namespace: uberon subset: human_reference_atlas synonym: "glandular part of endometrium" EXACT [FMA:86488] synonym: "uterine glands" EXACT [] synonym: "uterine glands set" EXACT [] xref: EMAPA:35308 xref: FMA:86488 xref: MA:0002732 is_a: UBERON:0004811 ! endometrium epithelium is_a: UBERON:0006929 ! glandular columnar epithelium is_a: UBERON:0007589 ! ciliated columnar oviduct epithelium intersection_of: UBERON:0006799 ! glandular epithelium intersection_of: part_of UBERON:0004811 ! endometrium epithelium relationship: part_of UBERON:0004811 ! endometrium epithelium property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012278 name: gland of nasal mucosa namespace: uberon def: "The nasal glands are the seromucous glands in the respiratory region of the nasal mucous membrane. The three major types of nasal glands are anterior serous glands, seromucous glands, and Bowman glands." [Wikipedia:Nasal_glands] subset: pheno_slim synonym: "glandula nasalis" EXACT LATIN [] synonym: "glandulae nasales" EXACT LATIN [] synonym: "nasal gland" BROAD [] xref: EMAPA:37871 {source="MA:th"} xref: FMA:321518 xref: NCIT:C22725 xref: SCTID:368881007 xref: UMLS:C1522269 {source="ncithesaurus:Nose_Nasal_Cavity_Nasal_Gland_MMHCC"} xref: Wikipedia:Nasal_glands is_a: UBERON:0002365 ! exocrine gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001826 ! nasal cavity mucosa relationship: has_part CL:0000159 ! seromucus secreting cell relationship: part_of UBERON:0001826 ! nasal cavity mucosa [Term] id: UBERON:0012290 name: fused carpal bones 2 and 3 namespace: uberon def: "A carpal bone that is formed from the fusion of the 2nd and 3rd distal carpal bones." [UBERON:skansa] synonym: "carpals 2+3" RELATED [] synonym: "fused carpals 2 and 3" EXACT [] is_a: UBERON:0001481 ! distal carpal bone intersection_of: UBERON:0001435 ! carpal bone intersection_of: derived_from_ancestral_fusion_of UBERON:0001431 ! distal carpal bone 2 intersection_of: derived_from_ancestral_fusion_of UBERON:0001432 ! distal carpal bone 3 relationship: derived_from_ancestral_fusion_of UBERON:0001431 ! distal carpal bone 2 relationship: derived_from_ancestral_fusion_of UBERON:0001432 ! distal carpal bone 3 [Term] id: UBERON:0012291 name: lateral malleolus of fibula namespace: uberon def: "Malleolus is the name for the bony prominence on each side of the ankle." [Wikipedia:Malleolus] subset: human_reference_atlas synonym: "distal extremity of fibula" RELATED [Wikipedia:Malleolus#Lateral_malleolus] synonym: "external malleolus of fibula" RELATED [Wikipedia:Malleolus#Lateral_malleolus] synonym: "fibular malleolus" RELATED [] synonym: "lateral malleolus" BROAD [FMA:35502] synonym: "malleolar bone" NARROW SENSU [] synonym: "malleolar bone of ankle" NARROW SENSU [] xref: EMAPA:37893 {source="MA:th"} xref: FMA:35502 xref: SCTID:361795009 xref: Wikipedia:Malleolus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: part_of UBERON:0004410 ! distal epiphysis of fibula property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In bovids, the distal end of the fibula is present only as the lateral malleolus, a separate bone that articulates with the lateral side of the distal tibia." xsd:string {scope="NCBITaxon:9895", seeAlso="UBERON:0004410", source="UBERON:skansa"} [Term] id: UBERON:0012292 name: embryonic cloacal fold namespace: uberon def: "One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly." [MP:0011836, MP:anna] comment: We presume this is distinct from AAO:0001003, an external integumentary structure - check with amphibian anatomy ontology developers. AO notes: the text def states mesenchymal swelling, EHDAA2 splits into mesenchymal and epithelial parts synonym: "cloacal fold" BROAD [EHDAA2:0004009] xref: EHDAA2:0004009 is_a: UBERON:0000481 ! multi-tissue structure relationship: adjacent_to UBERON:0006217 ! cloacal membrane relationship: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0012469 {source="EHDAA2"} ! external anal region [Term] id: UBERON:0012299 name: mucosa of urethra namespace: uberon def: "A mucosa that is part of a urethra." [OBOL:automatic] synonym: "mucous membrane of urethra" EXACT [FMA:76904] synonym: "tunica mucosa urethrae" EXACT [FMA:TA] synonym: "urethral mucosa" EXACT [FMA:76904] xref: EMAPA:37912 {source="MA:th"} xref: FMA:76904 xref: SCTID:362229009 is_a: UBERON:0000344 ! mucosa is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0012314 name: embryonic facial prominence namespace: uberon def: "One of five swellings formed during the development of the face." [http://www.indiana.edu/~anat550/hnanim/face/face.html] synonym: "embryonic facial process" RELATED [] synonym: "facial primordium" RELATED [] synonym: "primordium of face" RELATED [] xref: FMA:293103 xref: SCTID:89066004 is_a: UBERON:0002050 ! embryonic structure relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0012320 name: cervical artery namespace: uberon def: "An artery of the neck." [https://orcid.org/0000-0002-6601-2165] xref: EMAPA:37075 {source="MA:th"} xref: NCIT:C52850 xref: UMLS:C1707349 {source="ncithesaurus:Cervical_Artery"} is_a: UBERON:0001637 ! artery is_a: UBERON:0003502 ! neck blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0000974 ! neck [Term] id: UBERON:0012321 name: deep cervical artery namespace: uberon def: "The deep cervical artery (Profunda cervicalis) is an artery of the neck." [Wikipedia:Deep_cervical_artery] subset: human_reference_atlas synonym: "profunda cervicalis" RELATED [Wikipedia:Deep_cervical_artery] xref: FMA:10659 xref: SCTID:244223002 xref: Wikipedia:Deep_cervical_artery is_a: UBERON:0012320 ! cervical artery intersection_of: UBERON:0012320 ! cervical artery intersection_of: part_of UBERON:0035551 ! deep vasculature relationship: branching_part_of UBERON:0004688 {source="FMA"} ! costo-cervical trunk relationship: part_of UBERON:0004688 ! costo-cervical trunk relationship: part_of UBERON:0035551 ! deep vasculature property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012324 name: transverse cervical artery namespace: uberon def: "The transverse cervical artery (transverse artery of neck, transversa colli artery) is a branch of the thyrocervical trunk, running at a higher level than the suprascapular artery." [Wikipedia:Transverse_cervical_artery] subset: human_reference_atlas synonym: "cervical artery" RELATED [MA:0001936, Wikipedia:Transverse_cervical_artery] synonym: "cervical transverse artery" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "descending branch of the transverse cervical" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transversalis artery colli" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transversalis colli artery" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transverse cervical" RELATED [Wikipedia:Transverse_cervical_artery] synonym: "transverse cervical vessels" RELATED [Wikipedia:Transverse_cervical_artery] xref: FMA:10664 xref: MA:0001936 xref: SCTID:244224008 xref: Wikipedia:Transverse_cervical_artery is_a: UBERON:0012320 ! cervical artery property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000012 "Unclear if MA class belongs here or in parent" xsd:string {external_ontology="MA"} [Term] id: UBERON:0012329 name: keratinized stratified squamous epithelium namespace: uberon def: "Keratinized stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesize and accumulate keratin." [FMA:45568, Wikipedia:Stratified_squamous_epithelium#Keratinized] synonym: "epithelium stratificatum squamosum cornificatum" EXACT LATIN [FMA:45568] xref: FMA:45568 xref: Wikipedia:Stratified_squamous_epithelium#Keratinized is_a: UBERON:0006915 ! stratified squamous epithelium intersection_of: UBERON:0006915 ! stratified squamous epithelium intersection_of: has_part GO:0045095 ! keratin filament relationship: has_part GO:0045095 ! keratin filament [Term] id: UBERON:0012332 name: broad ligament of uterus namespace: uberon def: "A broad fold of peritoneum that extends from the side of the uterus to the wall of the pelvis." [MESH:A02.513.170, Wikipedia:Broad_ligament_of_the_uterus] subset: human_reference_atlas synonym: "broad ligament" RELATED [MESH:A02.513.170] synonym: "broad uterine ligament" EXACT [FMA:16516] synonym: "ligamentum latum uteri" RELATED LATIN [] xref: FMA:16516 xref: MESH:D001956 xref: NCIT:C12318 xref: SCTID:362723009 xref: UMLS:C0006205 {source="ncithesaurus:Broad_Ligament"} xref: Wikipedia:Broad_ligament_of_the_uterus is_a: UBERON:0000211 {source="MESH"} ! ligament is_a: UBERON:0004120 ! mesoderm-derived structure relationship: connects UBERON:0000459 ! uterine wall relationship: connects UBERON:0002355 ! pelvic region of trunk relationship: part_of UBERON:0002095 ! mesentery property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012354 name: acropodium region namespace: uberon def: "The segment of the autopod that is distal to the metapodial region and consists of the digits." [https://orcid.org/0000-0002-6601-2165] synonym: "acropodial limb segment" EXACT [] synonym: "acropodial region" EXACT [] synonym: "acropodial segment of autopod" EXACT [] synonym: "set of digits" EXACT [] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0012139 ! segment of autopod intersection_of: UBERON:0012139 ! segment of autopod intersection_of: has_skeleton UBERON:0010543 ! acropodial skeleton relationship: distal_to UBERON:0009877 ! metapodium region relationship: has_skeleton UBERON:0010543 ! acropodial skeleton relationship: part_of UBERON:0012140 ! digitopodium region property_value: IAO:0000232 "class refers to an entire limb segment, not just the bones" xsd:string [Term] id: UBERON:0012355 name: manual acropodium region namespace: uberon def: "The segment of the manus that is distal to the metacarpal region and consists of the manual digits (fingers)." [https://orcid.org/0000-0002-6601-2165] synonym: "acropodial hindlimb segment" EXACT [] synonym: "acropodial region of manus" EXACT [] synonym: "acropodial segment of manus" EXACT [] synonym: "all fingers" EXACT [] synonym: "anterior acropodium" RELATED [] synonym: "anterior acropodium region" EXACT [] synonym: "anterior acropodium segment of limb" EXACT [] synonym: "digiti manus" EXACT [FMA:TA] synonym: "digits of hand" EXACT [FMA:75592] synonym: "fingers including thumb" EXACT [FMA:75592] synonym: "fingers set" EXACT [FMA:75592] synonym: "manual acropodium" RELATED [] synonym: "manual acropodium region" EXACT [] synonym: "manual acropodium segment of limb" EXACT [] synonym: "set of digits of hand" EXACT [FMA:75592] synonym: "set of fingers" EXACT [FMA:75592] xref: FMA:75592 is_a: UBERON:0005451 ! segment of manus is_a: UBERON:0012354 ! acropodium region intersection_of: UBERON:0012354 ! acropodium region intersection_of: part_of UBERON:0002398 ! manus relationship: has_skeleton UBERON:0010688 ! skeleton of manual acropodium relationship: part_of UBERON:0012141 ! manual digitopodium region property_value: IAO:0000232 "class refers to an entire limb segment, not just the bones" xsd:string [Term] id: UBERON:0012356 name: pedal acropodium region namespace: uberon def: "The segment of the pes that is distal to the metatarsal region and consists of the pedal digits (toes)." [https://orcid.org/0000-0002-6601-2165] synonym: "acropodial forelimb segment" EXACT [] synonym: "acropodial region of pes" EXACT [] synonym: "acropodial segment of pes" EXACT [] synonym: "all toes" EXACT [] synonym: "digits of foot" EXACT [FMA:70664] synonym: "pedal acropodium region" EXACT [] synonym: "set of toes" EXACT [FMA:70664] synonym: "toes" RELATED [FMA:70664] synonym: "toes set" EXACT [FMA:70664] xref: FMA:70664 xref: SCTID:362835004 is_a: UBERON:0005445 ! segment of pes is_a: UBERON:0012354 ! acropodium region intersection_of: UBERON:0012354 ! acropodium region intersection_of: part_of UBERON:0002387 ! pes relationship: has_skeleton UBERON:0010696 ! skeleton of pedal acropodium relationship: part_of UBERON:0012142 ! pedal digitopodium region property_value: IAO:0000232 "class refers to an entire limb segment, not just the bones" xsd:string [Term] id: UBERON:0012357 name: digitopodium bone namespace: uberon def: "A bone that is part of a the digitopodium skeleton - i.e. the acropodial skeleton or the metapodial skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "digit bone" RELATED COMPARATIVE_PREFERRED [] is_a: UBERON:0011250 ! autopod bone intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0012140 ! digitopodium region relationship: part_of UBERON:0012150 ! skeleton of digitopodium property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern [Term] id: UBERON:0012358 name: manual digitopodium bone namespace: uberon def: "A bone that is part of a the manual digitopodium skeleton - i.e. the fingers or the metacarpal skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "bone of forelimb digitopodium" EXACT [] xref: SCTID:265809008 is_a: UBERON:0005897 ! manus bone is_a: UBERON:0012357 ! digitopodium bone intersection_of: UBERON:0012357 ! digitopodium bone intersection_of: part_of UBERON:0002398 ! manus relationship: part_of UBERON:0012151 ! skeleton of manual digitopodium property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern [Term] id: UBERON:0012359 name: pedal digitopodium bone namespace: uberon def: "A bone that is part of a the pedal digitopodium skeleton - i.e. the toes or the metatarsal skeleton." [https://orcid.org/0000-0002-6601-2165] synonym: "bone of hindlimb digitopodium" EXACT [] is_a: UBERON:0005899 ! pes bone is_a: UBERON:0012357 ! digitopodium bone intersection_of: UBERON:0012357 ! digitopodium bone intersection_of: part_of UBERON:0002387 ! pes relationship: part_of UBERON:0012152 ! skeleton of pedal digitopodium property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern [Term] id: UBERON:0012360 name: bone of jaw namespace: uberon def: "A bone element that is part of a jaw region." [OBOL:automatic] synonym: "jaw bone" EXACT [] xref: EMAPA:35453 xref: MA:0003130 xref: SCTID:369003004 is_a: UBERON:0003462 ! facial bone is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001474 ! bone element intersection_of: part_of UBERON:0011595 ! jaw region relationship: part_of UBERON:0001708 ! jaw skeleton property_value: editor_note "Do not manually classify under here - bones are automatically classified" xsd:string [Term] id: UBERON:0012361 name: internal anal region namespace: uberon xref: EHDAA2:0004588 is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001353 {source="EHDAA2"} ! anal region [Term] id: UBERON:0012367 name: muscle layer of intestine namespace: uberon def: "A muscle layer that is part of an intestine." [OBOL:automatic] synonym: "intestinal muscularis propria" EXACT [FMA:15697] synonym: "muscularis externa of intestine" EXACT [FMA:15697] synonym: "smooth muscle of intestine" RELATED [] xref: FMA:15697 is_a: UBERON:0018261 ! muscular coat of digestive tract intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0000160 ! intestine relationship: part_of UBERON:0001262 {source="FMA"} ! wall of intestine [Term] id: UBERON:0012373 name: sympathetic nerve plexus namespace: uberon def: "A nerve plexus that is part of a sympathetic nervous system." [OBOL:automatic] subset: human_reference_atlas xref: EMAPA:37617 {source="MA:th"} xref: MA:0001160 is_a: UBERON:0001816 ! autonomic nerve plexus intersection_of: UBERON:0001810 ! nerve plexus intersection_of: part_of UBERON:0000013 ! sympathetic nervous system relationship: part_of UBERON:0000013 ! sympathetic nervous system property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012375 name: subserosa namespace: uberon def: "A layer of tissue between the muscularis and serosa." [Wikipedia:Subserosa] comment: Contains nerves, blood vessels, lymphatics and lymph nodes subset: human_reference_atlas xref: FMA:45636 xref: NCIT:C94494 xref: SCTID:2255006 xref: UMLS:C0225334 {source="ncithesaurus:Subserosa"} xref: Wikipedia:Subserosa is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: adjacent_to UBERON:0000042 ! serous membrane intersection_of: composed_primarily_of UBERON:0006815 ! areolar connective tissue relationship: adjacent_to UBERON:0000042 ! serous membrane relationship: composed_primarily_of UBERON:0006815 ! areolar connective tissue relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012378 name: muscle layer of urinary bladder namespace: uberon def: "A muscular coat that is part of a urinary bladder." [OBOL:automatic] subset: human_reference_atlas synonym: "bladder muscular coat" EXACT [] synonym: "muscle layer of urinary bladder" EXACT [FMA:15930] synonym: "muscular coat of bladder" EXACT [FMA:15930] synonym: "muscular coat of urinary bladder" EXACT [FMA:15930] synonym: "muscular layer of bladder" EXACT [FMA:15930] synonym: "muscular layer of urinary bladder" EXACT [FMA:15930] synonym: "tunica musculari vesicae" EXACT [FMA:TA] synonym: "tunica muscularis (vesica urinaria)" EXACT [FMA:TA] xref: FMA:15930 xref: NCIT:C32206 xref: UMLS:C1288327 {source="ncithesaurus:Bladder_Muscular_Coat"} is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0006660 ! muscular coat intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001255 ! urinary bladder relationship: has_part UBERON:0004228 ! urinary bladder smooth muscle relationship: part_of UBERON:0001256 {source="FMA"} ! wall of urinary bladder property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012416 name: respiratory system arterial smooth muscle namespace: uberon subset: human_reference_atlas xref: EMAPA:37567 {source="MA:th"} xref: MA:0001802 is_a: UBERON:0004297 ! respiratory system blood vessel smooth muscle is_a: UBERON:0004695 ! arterial system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003643 ! respiratory system arterial blood vessel relationship: part_of UBERON:0003643 ! respiratory system arterial blood vessel property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012418 name: respiratory system venous smooth muscle namespace: uberon def: "A smooth muscle tissue that is part of a respiratory system venous blood vessel." [OBOL:automatic] subset: human_reference_atlas xref: EMAPA:37586 {source="MA:th"} xref: MA:0001812 is_a: UBERON:0004696 ! venous system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0003476 ! respiratory system venous blood vessel relationship: part_of UBERON:0003476 ! respiratory system venous blood vessel property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012423 name: layer of microvilli namespace: uberon def: "A layer of microvilli, Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments[GO,modified]." [GO:0005902, Wikipedia:Microvillus] synonym: "microvilli" RELATED [MESH:A11.284.180.565] synonym: "microvillus" RELATED [FMA:67296] xref: FMA:67296 xref: MESH:D008871 xref: NCIT:C33112 xref: UMLS:C0026049 {source="ncithesaurus:Microvillus"} xref: Wikipedia:Microvillus is_a: UBERON:0005162 ! multi cell part structure relationship: composed_primarily_of GO:0005902 ! microvillus property_value: UBPROP:0000009 "a wide variety of physiological and cellular functions including absorption, secretion, cellular adhesion, and mechanotransduction" xsd:string property_value: UBPROP:0000009 "increases the surface area of a cell lining whilst minimizing increase in volume" xsd:string property_value: UBPROP:0000012 "FMA class represents an individual microvillus." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0012425 name: striated border microvillus layer namespace: uberon def: "A microvillus layer that is striated and found in the intestine." [http://medical-dictionary.thefreedictionary.com/striated+border, http://orcid.org/0000-0002-6601-2165] synonym: "striated border" RELATED [FMA:70978] xref: FMA:70978 xref: NCIT:C33634 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0012423 ! layer of microvilli relationship: part_of UBERON:0000160 ! intestine property_value: UBPROP:0000012 "FMA class represents an individual microvillus" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0012429 name: hematopoietic tissue namespace: uberon def: "Blood-forming tissue, consisting of reticular fibers and cells." [http://encyclopedia2.thefreedictionary.com/hematopoietic+tissue] synonym: "bone marrow tissue" NARROW [NCBITaxon:9606] synonym: "haemopoietic tissue" EXACT [FMA:14073] synonym: "hematopoietic tissue" EXACT [FMA:14073] synonym: "hemopoietic tissue" EXACT [FMA:14073] synonym: "textus haemopoieticus" EXACT [FMA:14073] xref: CALOHA:TS-2142 xref: FMA:14073 xref: NCIT:C13051 xref: UMLS:C0229619 {source="ncithesaurus:Hematopoietic_Tissue"} is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0034769 {source="FMA"} ! lymphomyeloid tissue intersection_of: UBERON:0000479 ! tissue intersection_of: site_of GO:0030097 ! hemopoiesis relationship: part_of UBERON:0002371 {gci_relation="part_of", gci_filler="NCBITaxon:9606", source="FMA"} ! bone marrow relationship: part_of UBERON:0002390 {source="defitional"} ! hematopoietic system relationship: site_of GO:0030097 ! hemopoiesis property_value: UBPROP:0000008 "Bone marrow in humans, kidney interstitium in Danio, within a stroma of reticuloendothelial tissue" xsd:string [Term] id: UBERON:0012430 name: tunica fibrosa of eyeball namespace: uberon def: "The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth." [Wikipedia:Fibrous_tunic_of_eyeball] synonym: "corneosclera" RELATED [Wikipedia:Fibrous_tunic_of_eyeball] synonym: "fibrous layer of eyeball" EXACT [FMA:58102] synonym: "fibrous tunic" RELATED [Wikipedia:Fibrous_tunic_of_eyeball] synonym: "tunica fibrosa" BROAD [] xref: FMA:58102 xref: SCTID:361318005 xref: Wikipedia:Fibrous_tunic_of_eyeball is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0004923 {source="FMA"} ! organ component layer is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: has_part UBERON:0000964 ! cornea relationship: has_part UBERON:0001773 ! sclera relationship: part_of UBERON:0010230 ! eyeball of camera-type eye property_value: RO:0002175 NCBITaxon:7955 {source="DOI:10.1177/0192623311409597"} [Term] id: UBERON:0012463 name: cloacal lumen namespace: uberon def: "An anatomical space that is enclosed by a cloaca." [OBOL:automatic] synonym: "cloaca lumen" EXACT [ZFA:0000330] synonym: "cloacal chamber" EXACT [ZFA:0000330] xref: TAO:0000330 xref: ZFA:0000330 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000162 ! cloaca relationship: luminal_space_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0012465 {source="cjm"} ! lumen of terminal part of digestive tract property_value: UBPROP:0000012 "the ZFA class belongs here as it is an anatomical space. See https://sourceforge.net/p/obo/zebrafish-anatomy-zfa-term-requests/102/" xsd:string {external_ontology="ZFA"} [Term] id: UBERON:0012464 name: cloacal vent namespace: uberon def: "The opening of the cloacal chamber to the outside of the organism. Birds maintain a single cloacal opening throughout their lives." [http://orcid.org/0000-0002-6601-2165] synonym: "cloacal opening" EXACT [] synonym: "cloacal orifice" RELATED [] synonym: "vent" RELATED [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000161 ! orifice intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012465 name: lumen of terminal part of digestive tract namespace: uberon def: "An anatomical space that is enclosed by a terminal part of digestive tract." [OBOL:automatic] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0006866 ! terminal part of digestive tract relationship: luminal_space_of UBERON:0006866 ! terminal part of digestive tract relationship: part_of UBERON:0006866 ! terminal part of digestive tract property_value: UBPROP:0000008 "includes the cloacal lumen, in species where this is present" xsd:string [Term] id: UBERON:0012466 name: extraembryonic cavity namespace: uberon synonym: "extraembryonic cavities" RELATED PLURAL [EHDAA2:0000472] xref: EHDAA2:0000472 xref: EMAPA:16054 xref: VHOG:0000767 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: part_of UBERON:0016887 ! entire extraembryonic component relationship: part_of UBERON:0016887 ! entire extraembryonic component [Term] id: UBERON:0012467 name: enclosed anatomical space namespace: uberon def: "An anatomical space with no opening to another space or to the exterior." [AEO:0000222] synonym: "closed anatomical space" EXACT [] xref: AEO:0000222 is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: has_quality PATO:0000608 ! closed relationship: has_quality PATO:0000608 ! closed [Term] id: UBERON:0012468 name: anal tooth namespace: uberon def: "Triangular calcified papillae (often five) placed radially around the anus of some Holothuriidae." [http://species-identification.org/species.php?species_group=nasc&selected=definitie&menuentry=woordenlijst&record=Anal%20teeth, https://orcid.org/0000-0002-6601-2165, https://www.karger.com/Article/Pdf/142845] synonym: "anal teeth" EXACT PLURAL [] synonym: "calcified anal papilla" RELATED [] synonym: "cloacal tooth" RELATED [] synonym: "perianal tooth" RELATED [] is_a: UBERON:0003913 ! tooth-like structure intersection_of: UBERON:0003913 ! tooth-like structure intersection_of: part_of UBERON:0001353 ! anal region relationship: only_in_taxon NCBITaxon:7586 ! Echinodermata relationship: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0012469 name: external anal region namespace: uberon xref: EHDAA2:0004589 is_a: UBERON:0000481 ! multi-tissue structure relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001353 {source="EHDAA2"} ! anal region [Term] id: UBERON:0012475 name: skeleton of pectoral complex namespace: uberon def: "The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "bones of upper limb" RELATED [FMA:24139] synonym: "ossa membri superioris" RELATED [FMA:TA] synonym: "pectoral complex skeleton" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "set of bones of upper limb" RELATED [FMA:24139] synonym: "skeleton of anterior limb/fin and girdle" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "upper limb skeleton" RELATED [FMA:24139] xref: FMA:24139 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0010708 ! pectoral complex relationship: part_of UBERON:0002091 ! appendicular skeleton relationship: part_of UBERON:0010708 {source="FMA"} ! pectoral complex relationship: skeleton_of UBERON:0010708 ! pectoral complex [Term] id: UBERON:0012476 name: skeleton of pelvic complex namespace: uberon def: "The collection of all skeletal elements in a pelvic complex - i.e. the combination of free limb or fin plus pelvic girdle." [https://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "bones of lower limb" RELATED [FMA:24140] synonym: "lower limb skeleton" RELATED [FMA:24140] synonym: "ossa membri inferioris" RELATED [FMA:TA] synonym: "pelvic complex skeleton" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "set of bones of lower limb" RELATED [FMA:24140] synonym: "skeleton of posterior limb/fin and girdle" RELATED [https://orcid.org/0000-0002-6601-2165] xref: FMA:24140 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0010912 ! subdivision of skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:0010709 ! pelvic complex relationship: part_of UBERON:0002091 ! appendicular skeleton relationship: part_of UBERON:0010709 {source="FMA"} ! pelvic complex relationship: skeleton_of UBERON:0010709 ! pelvic complex [Term] id: UBERON:0012477 name: dorsal part of neck namespace: uberon def: "The posterior region of the neck, including the suboccipital region." [MP:0012723] subset: pheno_slim synonym: "back of neck" EXACT [FMA:24189] synonym: "hindneck" RELATED [] synonym: "nape" BROAD [BTO:0000957] synonym: "nape of neck" EXACT [] synonym: "neck back" EXACT [FMA:24189] synonym: "nucha" EXACT [FMA:24189] synonym: "nuchal region" EXACT [FMA:24189] synonym: "posterior cervical region" EXACT [FMA:24189] synonym: "posterior neck region" EXACT [FMA:24189] synonym: "posterior part of neck" EXACT [FMA:24189] synonym: "regio cervicalis posterior" EXACT [FMA:TA] xref: BTO:0000957 xref: FMA:24189 xref: SCTID:182326009 xref: SCTID:304036007 is_a: UBERON:0005434 {source="FMA"} ! cervical region relationship: in_dorsal_side_of UBERON:0000974 {source="FMA"} ! neck relationship: part_of UBERON:0001137 {source="FMA"} ! dorsum property_value: UBPROP:0000007 "nuchal" xsd:string [Term] id: UBERON:0012478 name: cloacal gland namespace: uberon def: "A gland that is part of a cloaca." [OBOL:automatic] is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012480 name: cloacal mucosa namespace: uberon alt_id: UBERON:0003349 def: "A mucosa that is part of a cloaca [Automatically generated definition]." [OBOL:automatic] synonym: "cloaca mucosa" EXACT [] synonym: "cloaca mucosa of organ" EXACT [] synonym: "cloaca mucous membrane" EXACT [] synonym: "cloaca organ mucosa" EXACT [] synonym: "cloacal mucous membrane" EXACT [] synonym: "mucosa of cloaca" EXACT [] synonym: "mucosa of organ of cloaca" EXACT [] synonym: "mucous membrane of cloaca" EXACT [] synonym: "organ mucosa of cloaca" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000344 ! mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012481 name: cloacal epithelium namespace: uberon def: "An epithelium that is part of a cloaca." [http://orcid.org/0000-0002-6601-2165] synonym: "cloacal endoderm" RELATED [EMAPA:27577] xref: EMAPA:27577 xref: EMAPA:36070 xref: ZFA:0005783 is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca property_value: UBPROP:0000001 "cloacal epithelium (cle) (syn: cloacal endoderm) (TS17-TS20): the cloacal epithelium is derived from endoderm and lines the cloacal cavity. It is marked by Shh and Cdh1 and lines the cloacal lumen. The cloacal epithelium gives rise to the urogenital sinus epithelium, hindgut epithelium and the urethral plate epithelium." xsd:string {source="EMAPA:27577"} [Term] id: UBERON:0012482 name: submucosa of cloaca namespace: uberon def: "A submucosa that is part of a cloaca [Automatically generated definition]." [OBOL:automatic] synonym: "cloaca submucosa" EXACT [] synonym: "cloacal submucosa" EXACT [] is_a: UBERON:0018257 ! submucosa of digestive tract intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012483 name: serosa of cloaca namespace: uberon def: "A serous membrane that is part of a cloaca [Automatically generated definition]." [OBOL:automatic] synonym: "cloaca serosa" EXACT [] synonym: "cloaca serous membrane" EXACT [] synonym: "cloacal serosa" EXACT [] synonym: "serous membrane of cloaca" EXACT [] synonym: "visceral peritoneum of cloaca" EXACT [] is_a: UBERON:0000042 ! serous membrane intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012485 name: cloacal villus namespace: uberon synonym: "cloacal villi" EXACT PLURAL [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0012423 ! layer of microvilli intersection_of: UBERON:0012423 ! layer of microvilli intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012486 name: muscle layer of cloaca namespace: uberon def: "A muscular coat that is part of a cloaca." [OBOL:automatic] synonym: "muscularis externa of cloaca" EXACT [] synonym: "smooth muscle of cloaca" RELATED [] is_a: UBERON:0018261 ! muscular coat of digestive tract intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0012488 name: muscle layer of duodenum namespace: uberon def: "A muscular coat that is part of a duodenum." [OBOL:automatic] synonym: "duodenal muscularis propria" EXACT [FMA:14944] synonym: "muscularis externa of duodenum" EXACT [FMA:14944] synonym: "muscularis propria of duodenum" RELATED [https://orcid.org/0000-0002-6601-2165] synonym: "smooth muscle of duodenum" RELATED [https://orcid.org/0000-0002-6601-2165] xref: FMA:14944 xref: SCTID:362147007 is_a: UBERON:0011201 ! muscle layer of small intestine intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum [Term] id: UBERON:0012489 name: muscle layer of colon namespace: uberon def: "A muscular coat that is part of a colon." [OBOL:automatic] subset: human_reference_atlas synonym: "colon muscularis" RELATED [MA:0003198] synonym: "colonic muscularis propria" EXACT [FMA:14986] synonym: "muscular coat of colon" EXACT [FMA:14986] synonym: "muscular layer of colon" EXACT [FMA:14986] synonym: "muscularis externa of colon" EXACT [FMA:14986] synonym: "tunica muscularis coli" EXACT [FMA:TA] xref: EMAPA:27383 xref: FMA:14986 xref: MA:0003198 xref: SCTID:362158003 is_a: UBERON:0011198 ! muscle layer of large intestine intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001155 ! colon relationship: part_of UBERON:0001155 ! colon property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0012490 name: muscle layer of anal canal namespace: uberon def: "A muscular coat that is part of a anal canal." [OBOL:automatic] synonym: "anal canal muscularis propria" EXACT [] synonym: "anal muscularis propria" EXACT [FMA:15708] synonym: "muscular coat of anal canal" EXACT [] synonym: "muscular layer of anal canal" EXACT [] synonym: "muscularis externa of anal canal" EXACT [] synonym: "muscularis propria of anal canal" EXACT [FMA:15708] xref: FMA:15708 xref: SCTID:362171000 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0011198 ! muscle layer of large intestine intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0000159 ! anal canal relationship: part_of UBERON:0000159 ! anal canal [Term] id: UBERON:0012499 name: serosa of uterine tube namespace: uberon def: "A serous membrane that is part of a fallopian tube." [OBOL:automatic] synonym: "serosa of fallopian tube" EXACT [FMA:18316] synonym: "serosa of oviduct" EXACT [FMA:18316] synonym: "serous coat of uterine tube" EXACT [FMA:18316] synonym: "tunica serosa (tuba uterina)" EXACT [FMA:18316] synonym: "tunica serosa tubae uterinae" EXACT [FMA:TA] synonym: "uterine tubal serosa" EXACT [FMA:18316] synonym: "uterine tube serosa" EXACT [FMA:18316] xref: FMA:18316 xref: SCTID:259593000 is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: part_of UBERON:0003889 ! fallopian tube [Term] id: UBERON:0012504 name: adventitia of esophagus namespace: uberon def: "An adventitia that is part of a esophagus." [OBOL:automatic] synonym: "adventitia of oesophagus" EXACT [FMA:63006] synonym: "adventitious layer of esophagus" EXACT [FMA:63006] synonym: "esophageal adventitia" EXACT [FMA:63006] synonym: "esophagus adventitia" EXACT [FMA:63006] synonym: "tunica adventitia (esophagus)" EXACT [FMA:63006] synonym: "tunica adventitia oesophageae" EXACT [FMA:TA] xref: FMA:63006 xref: SCTID:85950006 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005742 ! adventitia intersection_of: UBERON:0005742 ! adventitia intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus [Term] id: UBERON:0012615 name: umbilical smooth muscle namespace: uberon def: "A smooth muscle tissue that is part of a umbilical cord." [OBOL:automatic] xref: BTO:0001847 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002331 ! umbilical cord relationship: part_of UBERON:0002331 ! umbilical cord [Term] id: UBERON:0012650 name: gastroduodenal junction namespace: uberon def: "An anatomical junction that connects a stomach and connects a duodenum." [OBOL:automatic] xref: FMA:17046 xref: SCTID:264014000 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:1100000 ! digestive tract junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0000945 ! stomach intersection_of: connects UBERON:0002114 ! duodenum relationship: connects UBERON:0000945 ! stomach relationship: connects UBERON:0002114 ! duodenum relationship: part_of UBERON:0000945 ! stomach [Term] id: UBERON:0012651 name: mucosa of gastroduodenal junction namespace: uberon def: "A mucosa that is part of a gastroduodenal junction." [OBOL:automatic] synonym: "gastroduodenal mucosa" EXACT [BTO:0005415] xref: BTO:0005415 is_a: UBERON:0001199 ! mucosa of stomach intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0012650 ! gastroduodenal junction relationship: part_of UBERON:0001199 ! mucosa of stomach relationship: part_of UBERON:0012650 ! gastroduodenal junction [Term] id: UBERON:0013118 name: sulcus of brain namespace: uberon def: "A depression or fissure in the surface of the brain. It surrounds the gyri, creating the characteristic appearance of the brain in humans and other large mammals." [https://github.com/obophenotype/uberon/issues/315, Wikipedia:Sulcus_(neuroanatomy)] subset: cumbo synonym: "cerebral sulci" EXACT PLURAL [DHBA:10610] synonym: "cerebral sulci" RELATED [NeuroNames:1208] synonym: "cerebral sulcus" RELATED [NeuroNames:1208] synonym: "fissure of brain" NARROW [Wikipedia:Sulcus_(neuroanatomy)] synonym: "sulci & spaces" BROAD PLURAL [HBA:9352] synonym: "sulcus" BROAD [NLX:144078] xref: DHBA:10610 xref: HBA:9352 xref: NCIT:C32292 xref: neuronames:1208 xref: SCTID:279337001 xref: Wikipedia:Sulcus_(neuroanatomy) is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000093 ! sulcus intersection_of: UBERON:0000093 ! sulcus intersection_of: part_of UBERON:0000955 ! brain relationship: only_in_taxon NCBITaxon:40674 ! Mammalia relationship: part_of UBERON:0000955 ! brain relationship: surrounds UBERON:0000200 ! gyrus property_value: editor_note "sulci are considered absent from lissencephalic mammals such as mice, but they may possess fissures. For example, the Allen mouse brain Atlas includes hippocampal, rhinal and choroid fissure. For this reason we do not place a taxon constraint on this class" xsd:string property_value: RO:0002174 NCBITaxon:10088 property_value: UBPROP:0000001 "Indentation on the surface of the brain or spinal cord that forms a recognizable landmark, e.g., central sulcus, sulcus limitans (CUMBO)" xsd:string {source="http://neurolex.org/wiki/Cumbo_terms"} [Term] id: UBERON:0013121 name: proximal epiphysis of phalanx of pes namespace: uberon synonym: "basal epiphysis of phalanx of foot" EXACT [FMA:32888] synonym: "base of phalanx of foot" EXACT [FMA:32888] synonym: "basis phalangis (pedis)" EXACT [FMA:32888] synonym: "basis phalangis pedis" EXACT [FMA:TA] synonym: "proximal epiphysis of phalanx of toe" EXACT [FMA:32888] xref: FMA:32888 is_a: UBERON:0004447 ! proximal epiphysis of phalanx is_a: UBERON:0011973 ! epiphysis of phalanx of pes intersection_of: UBERON:0004380 ! proximal epiphysis intersection_of: part_of UBERON:0001449 ! phalanx of pes relationship: part_of UBERON:0001449 ! phalanx of pes [Term] id: UBERON:0013122 name: distal epiphysis of phalanx of pes namespace: uberon synonym: "caput phalangis (pedis)" EXACT [FMA:32890] synonym: "caput phalangis pedis" EXACT [FMA:TA] synonym: "distal end of phalanx of foot" EXACT [FMA:32890] synonym: "distal epiphysis of phalanx of toe" EXACT [FMA:32890] synonym: "head of phalanx of foot" EXACT [FMA:32890] synonym: "ungual tuberosity of distal phalanx of toe" RELATED [FMA:32890] xref: FMA:32890 xref: SCTID:236801009 is_a: UBERON:0004448 ! distal epiphysis of phalanx is_a: UBERON:0011973 ! epiphysis of phalanx of pes intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0001449 ! phalanx of pes relationship: part_of UBERON:0001449 ! phalanx of pes [Term] id: UBERON:0013126 name: vein of abdomen namespace: uberon def: "A vein that is part of a abdomen." [OBOL:automatic] subset: grouping_class synonym: "abdominal vein" EXACT [] xref: SCTID:281473003 is_a: UBERON:0001638 ! vein is_a: UBERON:0003497 ! abdomen blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0000916 ! abdomen property_value: editor_note "TODO mirror representation of abdominal aorta" xsd:string property_value: IAO:0000232 "this class groups all veins that are in the abdomen. The term 'abdominal vein' may have specific meanings in different contexts. The lateral abdominal veins are present in fishes but usually merged or absent in tetrapods; in amphibians, the L&R abdominal veins merge into the ventral abdominal vein" xsd:string [Term] id: UBERON:0013135 name: interdental plate namespace: uberon def: "The interdental plate refers to the bone-filled mesial-distal region between the teeth." [Wikipedia:Interdental_plate] xref: Wikipedia:Interdental_plate is_a: UBERON:0005913 ! zone of bone organ is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0005913 ! zone of bone organ intersection_of: located_in UBERON:0012111 ! diastema relationship: located_in UBERON:0012111 ! diastema relationship: part_of UBERON:0001708 ! jaw skeleton property_value: UBPROP:0000008 "In paleobiology, the presence or absence of the interdental plate can determine the place of an animal in the evolutionary scale, and paleontologists use the interdental plate when trying to classify a new specimen. Thecodont reptiles and theropod dinosaur fossils have an interdental plate, whereas acrodont reptiles such as Sphenodontia do not.[3] Its presence in Archaeopteryx, an extinct avian, resulted in the proposal of the dinosaur-bird connection" xsd:string {source="WP"} [Term] id: UBERON:0013136 name: vein of lip namespace: uberon def: "A vein that drains a lip." [OBOL:automatic] synonym: "labial vein" RELATED [] synonym: "labial vein of face" EXACT [] synonym: "lip vein" EXACT [OBOL:automatic] synonym: "vena labialis" EXACT LATIN [] xref: SCTID:367664002 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001833 ! lip relationship: drains UBERON:0001833 ! lip relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0001653 {source="FMA"} ! facial vein [Term] id: UBERON:0013139 name: ligament of liver namespace: uberon def: "A nonskeletal ligament that is part of a liver." [OBOL:automatic] synonym: "hepatic ligament" EXACT [FMA:15820] synonym: "liver ligament" EXACT [] xref: FMA:15820 xref: NCIT:C32997 xref: SCTID:48536008 xref: UMLS:C0230238 {source="ncithesaurus:Liver_Ligament"} is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005172 ! abdomen element is_a: UBERON:0008845 ! nonskeletal ligament is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0008845 ! nonskeletal ligament intersection_of: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 ! liver [Term] id: UBERON:0013140 name: systemic vein namespace: uberon def: "Any vein within the general circulation that transports blood back to the right atrium of the heart." [ncithesaurus:Systemic_Vein] synonym: "systemic venous tree organ part" EXACT [FMA:66644] xref: FMA:66644 xref: NCIT:C33719 xref: SCTID:244389004 xref: UMLS:C0447117 {source="ncithesaurus:Systemic_Vein"} is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0004581 ! systemic venous system relationship: part_of UBERON:0004581 ! systemic venous system [Term] id: UBERON:0013156 name: 1st arch mandibular endoderm namespace: uberon synonym: "endoderm of mandibular component" EXACT [EMAPA:16384] xref: EHDAA2:0000033 xref: EMAPA:16384 is_a: UBERON:0003258 ! endoderm of foregut is_a: UBERON:0005291 ! embryonic tissue relationship: develops_from UBERON:0007122 {source="EHDAA2"} ! pharyngeal pouch 1 relationship: part_of UBERON:0007237 {source="EHDAA2"} ! 1st arch mandibular component relationship: part_of UBERON:0009722 {source="EHDAA2"} ! entire pharyngeal arch endoderm [Term] id: UBERON:0013158 name: foregut-midgut junction gland namespace: uberon def: "A gland that is part of a foregut-midgut junction." [OBOL:automatic] synonym: "gland of foregut-midgut junction" EXACT [EMAPA:17065] xref: EHDAA2:0000574 xref: EMAPA:17065 is_a: UBERON:0003408 ! gland of digestive tract intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0006235 ! foregut-midgut junction relationship: part_of UBERON:0006235 ! foregut-midgut junction [Term] id: UBERON:0013164 name: molariform tooth namespace: uberon def: "A molar or premolar." [ISBN:0073040584] synonym: "cheek tooth" RELATED [ISBN:0073040584] synonym: "molariform" RELATED [ISBN:0073040584] synonym: "postcanine tooth" EXACT [http://www.termwiki.com/EN\:postcanine_teeth] is_a: UBERON:0001091 ! calcareous tooth relationship: has_part UBERON:0006844 ! cusp of tooth [Term] id: UBERON:0013191 name: ovarian cortex namespace: uberon def: "The layer of the ovarian stroma lying immediately beneath the tunica albuginea, composed of connective tissue cells and fibers, among which are scattered primary and secondary (antral) follicles in various stages of development; the cortex varies in thickness according to the age of the individual, becoming thinner with advancing years; included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte; the zona pellucida, theca of follicle, antrum and liquor folliculi are also contained in the follicle; also in the cortex is the corpus luteum derived from the follicles." [MGI:anna] subset: human_reference_atlas subset: pheno_slim synonym: "cortex of ovary" EXACT [FMA:18613] synonym: "cortex ovarii (zona parenchymatosa)" EXACT [FMA:18613] xref: EMAPA:37927 {source="MA:th"} xref: FMA:18613 xref: NCIT:C33243 xref: UMLS:C0227878 {source="ncithesaurus:Ovarian_Cortex"} is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001851 ! cortex is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001851 ! cortex intersection_of: part_of UBERON:0000992 ! ovary relationship: part_of UBERON:0006960 ! ovary stroma property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0013232 name: serous acinus namespace: uberon def: "The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] synonym: "acinus of serous gland" EXACT [] xref: FMA:86279 is_a: UBERON:0011858 ! acinus of exocrine gland intersection_of: UBERON:0009842 ! glandular acinus intersection_of: part_of UBERON:0000409 ! serous gland relationship: composed_primarily_of CL:0000313 ! serous secreting cell relationship: part_of UBERON:0000409 ! serous gland [Term] id: UBERON:0013238 name: future glans namespace: uberon is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure union_of: UBERON:0013239 ! future glans penis union_of: UBERON:0013240 ! future glans clitoris relationship: has_potential_to_develop_into UBERON:0035651 ! glans relationship: part_of UBERON:0011757 ! differentiated genital tubercle [Term] id: UBERON:0013239 name: future glans penis namespace: uberon def: "A future glans that is part of a male genital tubercle." [OBOL:automatic] synonym: "glans of male genital tubercle" EXACT [] xref: EMAPA:29252 is_a: UBERON:0013238 ! future glans intersection_of: UBERON:0013238 ! future glans intersection_of: part_of UBERON:0006261 ! male genital tubercle relationship: part_of UBERON:0006261 {source="EMAPA"} ! male genital tubercle [Term] id: UBERON:0013240 name: future glans clitoris namespace: uberon def: "A future glans that is part of a female genital tubercle." [OBOL:automatic] synonym: "glans of female genital tubercle" EXACT [] xref: EMAPA:19170 is_a: UBERON:0013238 ! future glans intersection_of: UBERON:0013238 ! future glans intersection_of: part_of UBERON:0006233 ! female genital tubercle relationship: part_of UBERON:0006233 {source="EMAPA"} ! female genital tubercle [Term] id: UBERON:0013241 name: embryonic urethral groove namespace: uberon def: "The precursor of the urethra." [http://orcid.org/0000-0002-6601-2165] synonym: "sulcus urethralis primarius" EXACT LATIN [Wikipedia:Urethral_groove] synonym: "urethral groove" EXACT [] synonym: "urethral sulcus" EXACT [] xref: SCTID:361531004 xref: Wikipedia:Urethral_groove is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure relationship: develops_from UBERON:0004876 {source="Wikipedia"} ! urogenital fold property_value: UBPROP:0000008 "In humans, the urethral groove is a temporary linear indentation on the underside (ventral side) of the male penis during embryonic development. It typically appears around 8 weeks of gestation and becomes closed into a normal male urethra by the 12th week" xsd:string {source="Wikipedia:Urethral_groove"} [Term] id: UBERON:0013247 name: male paramesonephric duct namespace: uberon def: "An epithelial tube that develops from a Mullerian duct in a male. Later degenerates." [http://orcid.org/0000-0002-6601-2165] synonym: "degenerating mesonephric portion of male paramesonephric duct" RELATED [EMAPA:29161] xref: EHDAA2:0001052 xref: EMAPA:29161 xref: EMAPA:35661 is_a: UBERON:0003914 ! epithelial tube is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0012275 ! meso-epithelium intersection_of: UBERON:0003914 ! epithelial tube intersection_of: develops_from UBERON:0003890 ! Mullerian duct intersection_of: part_of UBERON:0000079 ! male reproductive system relationship: develops_from UBERON:0003890 {source="EHDAA2"} ! Mullerian duct relationship: part_of UBERON:0000079 {source="EHDAA2"} ! male reproductive system property_value: editor_note "consider separating the duct from the degenerating portion, as in EMAPA" xsd:string [Term] id: UBERON:0013279 name: diaphysis of fibula namespace: uberon def: "A diaphysis that is part of a fibula[Automatically generated definition]." [OBOL:automatic, Wikipedia:Body_of_fibula] synonym: "body of fibula" EXACT [FMA:33738] synonym: "corpus fibulae" EXACT [FMA:TA] synonym: "fibula diaphysis" EXACT [FMA:33738] synonym: "shaft of fibula" EXACT [FMA:33738] xref: EMAPA:37892 {source="MA:th"} xref: FMA:33738 xref: SCTID:302528006 xref: Wikipedia:Body_of_fibula is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0001446 ! fibula relationship: part_of UBERON:0001446 ! fibula property_value: UBPROP:0000001 "The body of fibula presents four borders - the antero-lateral, the antero-medial, the postero-lateral, and the postero-medial; and four surfaces - anterior, posterior, medial, and lateral[Wikipedia:Body_of_fibula]." xsd:string {source="Wikipedia:Body_of_fibula"} [Term] id: UBERON:0013280 name: diaphysis of tibia namespace: uberon def: "A diaphysis that is part of a tibia." [OBOL:automatic, Wikipedia:Body_of_tibia] synonym: "body of the tibia" RELATED [Wikipedia:Body_of_tibia] synonym: "body of tibia" EXACT [FMA:33125] synonym: "corpus tibiae" EXACT [FMA:TA] synonym: "shaft of tibia" EXACT [FMA:33125] synonym: "shaft of tibia" RELATED [Wikipedia:Body_of_tibia] synonym: "tibial diaphysis" EXACT [FMA:33125] xref: EMAPA:37770 {source="MA:th"} xref: FMA:33125 xref: MA:0003049 xref: SCTID:302525009 xref: Wikipedia:Body_of_tibia is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0000979 ! tibia relationship: part_of UBERON:0000979 ! tibia property_value: UBPROP:0000001 "The body of the tibia has three borders and three surfaces[Wikipedia:Body_of_tibia]." xsd:string {source="Wikipedia:Body_of_tibia"} [Term] id: UBERON:0013411 name: cranial cavity namespace: uberon def: "Anatomical cavity that is the lumen of the skull and contains the brain." [UBERON:cjm] synonym: "cavitas cranii" EXACT LATIN [FMA:9644, FMA:TA] synonym: "intracranial cavity" RELATED [Wikipedia:Cranial_cavity] synonym: "intracranial space" RELATED [Wikipedia:Cranial_cavity] xref: EMAPA:37497 {source="MA:th"} xref: FMA:9644 xref: MA:0003061 xref: NCIT:C77638 xref: neuronames:2806 xref: SCTID:264452006 xref: UMLS:C0230041 {source="ncithesaurus:Cranial_Cavity"} xref: Wikipedia:Cranial_cavity is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0003129 ! skull relationship: luminal_space_of UBERON:0003129 ! skull relationship: part_of UBERON:0003129 {source="Wikipedia"} ! skull property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/e/ee/Scheme_body_cavities-en.svg" xsd:anyURI [Term] id: UBERON:0013447 name: sagittal crest of skull namespace: uberon def: "A ridge of bone running lengthwise along the midline of the top of the skull of many mammalian and reptilian skulls and serves as an attachment site for the temporailis muscle[WP,modified]." [Wikipedia:Sagittal_crest] synonym: "crista sagittalis externa" EXACT [] synonym: "sagittal crest" BROAD [] synonym: "sagittal ridge" RELATED [] xref: Wikipedia:Sagittal_crest is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0003113 ! dermatocranium property_value: depicted_by "https://upload.wikimedia.org/wikipedia/commons/4/43/Paranthropus_aethiopicus.JPG" xsd:anyURI property_value: UBPROP:0000008 "Skulls of some dinosaur species, including tyrannosaurs, possessed well developed sagittal crests. Among mammals, dogs, cats, lions, and many other carnivores have sagittal crests, as do some leaf eaters, including tapirs and some apes. Sagittal crests are found in robust great apes, and some early hominins. Prominent sagittal crests are found among male gorillas and orangutans, and do occur but only rarely in male chimpanzees such as Bili Apes" xsd:string property_value: UBPROP:0000009 "The sagittal crest serves primarily for attachment of the temporalis muscle, which is one of the main chewing muscles" xsd:string property_value: UBPROP:0000012 "Compare with: AAO:0000384 parasagittal crest (UBERON:0013402)" xsd:string {external_ontology="AAO"} [Term] id: UBERON:0013463 name: temporal fossa namespace: uberon def: "The temporal fossa is a shallow depression on the side of the skull bounded by the temporal lines and terminating below the level of the zygomatic arch." [Wikipedia:Temporal_fossa] xref: FMA:75307 xref: NCIT:C33742 xref: SCTID:137157009 xref: UMLS:C0230010 {source="ncithesaurus:Temporal_Fossa"} xref: Wikipedia:Temporal_fossa is_a: UBERON:0004704 ! bone fossa relationship: part_of UBERON:0003129 {source="Wikipedia"} ! skull property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/b/bd/Fossatemporalis.PNG" xsd:anyURI [Term] id: UBERON:0013479 name: lung endothelium namespace: uberon def: "A blood vessel endothelium that is part of a lung [Automatically generated definition]." [OBOL:automatic] synonym: "respiratory endothelium" RELATED [BTO:0004128] xref: BTO:0004128 xref: CALOHA:TS-0573 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0000115 ! lung epithelium is_a: UBERON:0004702 ! respiratory system blood vessel endothelium intersection_of: UBERON:0004638 ! blood vessel endothelium intersection_of: part_of UBERON:0002048 ! lung [Term] id: UBERON:0013501 name: cloacal sphincter namespace: uberon def: "A sphincter muscle that is part of a cloaca." [OBOL:automatic] comment: the muscles of the cloacal sphincter specialise into the perineal muscles in mammals (Gegenbaur, 1883; Popowsky, 1899; Nishi, 1938). synonym: "sphincter cloacae" EXACT PLURAL [] xref: NCIT:C34129 xref: UMLS:C1516658 {source="ncithesaurus:Cloacal_Sphincter"} is_a: UBERON:0004590 ! sphincter muscle is_a: UBERON:0014783 ! cloacal muscle intersection_of: UBERON:0004590 ! sphincter muscle intersection_of: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0013503 name: caudal vertebra cartilage element namespace: uberon alt_id: UBERON:0013517 def: "A caudal vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "coccygeal vertebra cartilage element" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "coccygeal vertebral cartilage condensation group" EXACT [EHDAA2:0000260] synonym: "tail vertebral cartilage condensation" EXACT [EMAPA:18044] xref: EHDAA2:0000260 xref: EMAPA:18044 is_a: UBERON:0011094 ! vertebra cartilage element is_a: UBERON:0018142 ! caudal vertebra endochondral element is_a: UBERON:2001457 ! postcranial axial cartilage intersection_of: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0013504 ! caudal vertebra pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0001095 ! caudal vertebra [Term] id: UBERON:0013504 name: caudal vertebra pre-cartilage condensation namespace: uberon alt_id: UBERON:0013518 def: "A caudal vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] synonym: "coccygeal vertebra pre-cartilage condensation" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "tail vertebral pre-cartilage condensation" EXACT [EMAPA:18045] xref: EMAPA:18045 is_a: UBERON:0011095 ! vertebra pre-cartilage condensation is_a: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: UBERON:0018142 ! caudal vertebra endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0013505 name: cervical vertebra cartilage element namespace: uberon def: "A cervical vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "cervical vertebral cartilage condensation group" EXACT [EHDAA2:0000240] xref: EHDAA2:0000240 is_a: UBERON:0003601 ! neck cartilage is_a: UBERON:0011094 ! vertebra cartilage element is_a: UBERON:0015007 ! cervical vertebra endochondral element is_a: UBERON:2001457 ! postcranial axial cartilage intersection_of: UBERON:0015007 ! cervical vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0013506 ! cervical vertebra pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0002413 ! cervical vertebra [Term] id: UBERON:0013506 name: cervical vertebra pre-cartilage condensation namespace: uberon def: "A cervical vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0011095 ! vertebra pre-cartilage condensation is_a: UBERON:0015007 ! cervical vertebra endochondral element intersection_of: UBERON:0015007 ! cervical vertebra endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0013507 name: thoracic vertebra cartilage element namespace: uberon def: "A thoracic vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "thoracic vertebral cartilage condensation group" EXACT [EHDAA2:0002014] xref: EHDAA2:0002014 is_a: UBERON:0011094 ! vertebra cartilage element is_a: UBERON:0015008 ! thoracic vertebra endochondral element is_a: UBERON:2001457 ! postcranial axial cartilage intersection_of: UBERON:0015008 ! thoracic vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0013508 ! thoracic vertebra pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0002347 ! thoracic vertebra [Term] id: UBERON:0013508 name: thoracic vertebra pre-cartilage condensation namespace: uberon def: "A thoracic vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0011095 ! vertebra pre-cartilage condensation is_a: UBERON:0015008 ! thoracic vertebra endochondral element intersection_of: UBERON:0015008 ! thoracic vertebra endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0013509 name: lumbar vertebra cartilage element namespace: uberon def: "A lumbar vertebra endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "lumbar vertebral cartilage condensation group" EXACT [EHDAA2:0001038] xref: EHDAA2:0001038 is_a: UBERON:0011094 ! vertebra cartilage element is_a: UBERON:0015009 ! lumbar vertebra endochondral element is_a: UBERON:2001457 ! postcranial axial cartilage intersection_of: UBERON:0015009 ! lumbar vertebra endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0013510 ! lumbar vertebra pre-cartilage condensation relationship: has_potential_to_develop_into UBERON:0002414 ! lumbar vertebra [Term] id: UBERON:0013510 name: lumbar vertebra pre-cartilage condensation namespace: uberon def: "A lumbar vertebra endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0011095 ! vertebra pre-cartilage condensation is_a: UBERON:0015009 ! lumbar vertebra endochondral element intersection_of: UBERON:0015009 ! lumbar vertebra endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0013514 name: space surrounding organism namespace: uberon def: "The space that surrounds an organism." [https://orcid.org/0000-0002-6601-2165] synonym: "external to organism" EXACT [] synonym: "outside of body" EXACT [] is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: surrounds UBERON:0000468 ! multicellular organism relationship: surrounds UBERON:0000468 ! multicellular organism [Term] id: UBERON:0013515 name: subdivision of oviduct namespace: uberon def: "A section through the tube or network of tubes that connects the ovaries to the outside of the body." [http://orcid.org/0000-0002-6601-2165] subset: non_informative synonym: "subdivision of fallopian tube" NARROW [FMA:18302] synonym: "subdivision of oviduct" EXACT [FMA:18302] synonym: "subdivision of uterine tube" EXACT [] synonym: "uterine tube zone" EXACT [FMA:18302] synonym: "zone of uterine tube" EXACT [FMA:18302] xref: FMA:18302 is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0013522 ! subdivision of tube intersection_of: UBERON:0013522 ! subdivision of tube intersection_of: subdivision_of UBERON:0000993 ! oviduct relationship: part_of UBERON:0000993 ! oviduct relationship: subdivision_of UBERON:0000993 ! oviduct property_value: UBPROP:0000012 "FMA class may only represent the uterine portion" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0013522 name: subdivision of tube namespace: uberon is_a: UBERON:0000064 ! organ part relationship: has_part UBERON:0000060 ! anatomical wall relationship: has_part UBERON:0000464 ! anatomical space relationship: part_of UBERON:0000025 ! tube relationship: subdivision_of UBERON:0000025 ! tube [Term] id: UBERON:0013525 name: stomach lumen namespace: uberon def: "The anatomical space that is enclosed by a stomach." [http://orcid.org/0000-0002-6601-2165] synonym: "cavity of stomach" EXACT [FMA:14585] synonym: "gastric cavity" RELATED [FMA:14585] xref: EMAPA:18395 xref: FMA:14585 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000945 ! stomach relationship: luminal_space_of UBERON:0000945 ! stomach relationship: part_of UBERON:0000945 ! stomach relationship: part_of UBERON:0011565 {source="FMA"} ! lumen of gastrointestinal system property_value: UBPROP:0000001 "Organ cavity which is bound by the internal surface of the wall of stomach. Examples: There is only one cavity of stomach[FMA:14585]." xsd:string {source="FMA:14585"} [Term] id: UBERON:0013526 name: otocyst lumen namespace: uberon def: "An anatomical cavity that is part of a ear vesicle." [OBOL:automatic] synonym: "lumen of otocyst" EXACT [EMAPA:25363] xref: EHDAA2:0004121 xref: EMAPA:25363 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity is_a: UBERON:0007473 {source="EHDAA2"} ! lumen of epithelial sac intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0003051 ! ear vesicle relationship: develops_from UBERON:0006273 {source="EHDAA2"} ! otic pit relationship: luminal_space_of UBERON:0003051 ! ear vesicle relationship: part_of UBERON:0003051 {source="EHDAA2"} ! ear vesicle [Term] id: UBERON:0013581 name: metapodium bone 1 namespace: uberon def: "A metapodium bone that is part of a digit 1 plus metapodial segment." [OBOL:automatic] synonym: "metapodium 1" EXACT [] synonym: "metapodium I" EXACT [] is_a: UBERON:0003821 ! metapodium bone intersection_of: UBERON:0003821 ! metapodium bone intersection_of: part_of UBERON:5006048 ! digit 1 plus metapodial segment relationship: part_of UBERON:5006048 ! digit 1 plus metapodial segment [Term] id: UBERON:0013582 name: metapodium bone 2 namespace: uberon def: "A metapodium bone that is part of a digit 2 plus metapodial segment." [OBOL:automatic] synonym: "metapodium 2" EXACT [] synonym: "metapodium II" EXACT [] is_a: UBERON:0003821 ! metapodium bone intersection_of: UBERON:0003821 ! metapodium bone intersection_of: part_of UBERON:5006049 ! digit 2 plus metapodial segment relationship: part_of UBERON:5006049 ! digit 2 plus metapodial segment [Term] id: UBERON:0013583 name: metapodium bone 3 namespace: uberon def: "A metapodial bone that is associated with digit III." [http://orcid.org/0000-0002-6601-2165] synonym: "3rd metapodium bone" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "cannon bone" NARROW [NCBITaxon:9788, Wikipedia:Equine_forelimb_anatomy#Metacarpal_bones] synonym: "metapodial bone III" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "metapodium 3" EXACT [] synonym: "metapodium III" EXACT [] is_a: UBERON:0003821 ! metapodium bone intersection_of: UBERON:0003821 ! metapodium bone intersection_of: part_of UBERON:5006050 ! digit 3 plus metapodial segment relationship: part_of UBERON:5006050 ! digit 3 plus metapodial segment [Term] id: UBERON:0013584 name: metapodium bone 4 namespace: uberon def: "A metapodium bone that is part of a digit 4 plus metapodial segment." [OBOL:automatic] synonym: "metapodium 4" EXACT [] synonym: "metapodium IV" EXACT [] is_a: UBERON:0003821 ! metapodium bone intersection_of: UBERON:0003821 ! metapodium bone intersection_of: part_of UBERON:5006051 ! digit 4 plus metapodial segment relationship: part_of UBERON:5006051 ! digit 4 plus metapodial segment [Term] id: UBERON:0013585 name: metapodium bone 5 namespace: uberon def: "A metapodium bone that is part of a digit 5 plus metapodial segment." [OBOL:automatic] synonym: "metapodium 5" EXACT [] synonym: "metapodium V" EXACT [] is_a: UBERON:0003821 ! metapodium bone intersection_of: UBERON:0003821 ! metapodium bone intersection_of: part_of UBERON:5006052 ! digit 5 plus metapodial segment relationship: part_of UBERON:5006052 ! digit 5 plus metapodial segment [Term] id: UBERON:0013586 name: fused metapodial bones 3 and 4 namespace: uberon def: "An element formed from the fusion of metapodium 3 and metapodium 4 (i.e. either metatarsals 3 and 4 or metacarpals 3 and 4)." [http://orcid.org/0000-0001-7920-5321] synonym: "fused metapodials 3/4" EXACT [] synonym: "metapodial 3+4" RELATED [] synonym: "os metapodiale III et IV" EXACT LATIN [] is_a: UBERON:0003821 ! metapodium bone intersection_of: UBERON:0003821 ! metapodium bone intersection_of: derived_from_ancestral_fusion_of UBERON:0013583 ! metapodium bone 3 intersection_of: derived_from_ancestral_fusion_of UBERON:0013584 ! metapodium bone 4 relationship: derived_from_ancestral_fusion_of UBERON:0013583 ! metapodium bone 3 relationship: derived_from_ancestral_fusion_of UBERON:0013584 ! metapodium bone 4 property_value: IAO:0000232 "this class can be used in annotation when it is unclear whether the element is a fusion of the metacarpal and metatarsal elements." xsd:string property_value: RO:0002175 NCBITaxon:91561 [Term] id: UBERON:0013587 name: fused metacarpal bones 3 and 4 namespace: uberon def: "An element formed from the fusion of metacarpal 3 and metacarpal 4." [http://orcid.org/0000-0001-7920-5321] synonym: "fused metacarpal 3/4" EXACT [] synonym: "metacarpal 3+4" RELATED [] synonym: "os metacarpale III et IV" EXACT LATIN [NominaAnatomicaVeterinaria:2005] is_a: UBERON:0002374 ! metacarpal bone is_a: UBERON:0013586 ! fused metapodial bones 3 and 4 intersection_of: UBERON:0002374 ! metacarpal bone intersection_of: derived_from_ancestral_fusion_of UBERON:0003647 ! metacarpal bone of digit 3 intersection_of: derived_from_ancestral_fusion_of UBERON:0003648 ! metacarpal bone of digit 4 relationship: derived_from_ancestral_fusion_of UBERON:0003647 ! metacarpal bone of digit 3 relationship: derived_from_ancestral_fusion_of UBERON:0003648 ! metacarpal bone of digit 4 property_value: UBPROP:0000008 "In many artiodactyls, the 3rd & 4th metapodials are fused, creating a main metapodial." xsd:string [Term] id: UBERON:0013588 name: fused metatarsal bones 3 and 4 namespace: uberon def: "An element formed from the fusion of metatarsal 3 and metatarsal 4." [http://orcid.org/0000-0001-7920-5321] synonym: "fused metatarsal 3/4" EXACT [] synonym: "metatarsal 3+4" RELATED [] synonym: "os metatarsale III et IV (Ru)" EXACT LATIN [NominaAnatomicaVeterinaria:2005] is_a: UBERON:0001448 ! metatarsal bone is_a: UBERON:0013586 ! fused metapodial bones 3 and 4 intersection_of: UBERON:0001448 ! metatarsal bone intersection_of: derived_from_ancestral_fusion_of UBERON:0003652 ! metatarsal bone of digit 3 intersection_of: derived_from_ancestral_fusion_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: derived_from_ancestral_fusion_of UBERON:0003652 ! metatarsal bone of digit 3 relationship: derived_from_ancestral_fusion_of UBERON:0003653 ! metatarsal bone of digit 4 property_value: UBPROP:0000008 "In many artiodactyls, the 3rd & 4th metapodials are fused, creating a main metapodial." xsd:string [Term] id: UBERON:0013616 name: primary molar tooth namespace: uberon subset: pheno_slim synonym: "deciduous molar tooth" EXACT [FMA:84206] synonym: "primary molar tooth" EXACT [FMA:84206] synonym: "temporary molar tooth" EXACT [FMA:84206] xref: FMA:84206 xref: SCTID:368703003 is_a: UBERON:0003655 ! molar tooth is_a: UBERON:0007115 ! deciduous tooth intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0007116 ! primary dentition property_value: editor_note "TODO - logical definition" xsd:string [Term] id: UBERON:0013617 name: upper primary molar tooth namespace: uberon def: "A primary molar tooth that is part of a upper jaw region." [OBOL:automatic] synonym: "primary upper molar tooth" EXACT [] synonym: "upper deciduous molar" EXACT [] synonym: "upper deciduous molar tooth" EXACT [FMA:84210] synonym: "upper primary molar tooth" EXACT [FMA:84210] xref: FMA:84210 xref: SCTID:422318005 is_a: UBERON:0003666 ! upper jaw molar is_a: UBERON:0013616 ! primary molar tooth is_a: UBERON:0018616 ! primary upper tooth intersection_of: UBERON:0013616 ! primary molar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0013618 name: secondary molar tooth namespace: uberon subset: pheno_slim synonym: "permanent molar tooth" EXACT [FMA:84207] synonym: "secondary molar tooth" EXACT [FMA:84207] xref: FMA:84207 xref: SCTID:421593002 is_a: UBERON:0003655 ! molar tooth is_a: UBERON:0007775 ! secondary tooth intersection_of: UBERON:0003655 ! molar tooth intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0013619 name: upper secondary molar tooth namespace: uberon def: "A secondary molar tooth that is part of a upper jaw region." [OBOL:automatic] synonym: "maxillary secondary molar tooth" EXACT [FMA:55720] synonym: "upper permanent molar tooth" EXACT [FMA:55720] synonym: "upper secondary molar tooth" EXACT [FMA:55720] xref: FMA:55720 is_a: UBERON:0003666 ! upper jaw molar is_a: UBERON:0013618 ! secondary molar tooth is_a: UBERON:0018613 ! secondary upper tooth intersection_of: UBERON:0013618 ! secondary molar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0013620 name: lower primary molar tooth namespace: uberon def: "A primary molar tooth that is part of a lower jaw region." [OBOL:automatic] synonym: "lower deciduous molar tooth" EXACT [FMA:84213] synonym: "primary lower molar tooth" EXACT [] xref: FMA:84213 xref: SCTID:421482001 is_a: UBERON:0003667 ! lower jaw molar is_a: UBERON:0013616 ! primary molar tooth is_a: UBERON:0018617 ! primary lower tooth intersection_of: UBERON:0013616 ! primary molar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0013621 name: lower secondary molar tooth namespace: uberon def: "A secondary molar tooth that is part of a lower jaw region." [OBOL:automatic] synonym: "lower permanent molar" EXACT [] synonym: "lower permanent molar tooth" EXACT [FMA:55721] synonym: "mandibular secondary molar tooth" EXACT [FMA:55721] xref: FMA:55721 is_a: UBERON:0003667 ! lower jaw molar is_a: UBERON:0013618 ! secondary molar tooth is_a: UBERON:0018614 ! permanent lower tooth intersection_of: UBERON:0013618 ! secondary molar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0013630 name: short bone namespace: uberon def: "Short bones are designated as those bones that are as wide as they are long. Their primary function is to provide support and stability with little to no movement. They are one of five types of bones: long, short, flat, irregular and sesamoid. Examples of these bones include the tarsals in the foot and the carpals in the hand." [Wikipedia:Short_bone] xref: FMA:7475 xref: NCIT:C33545 xref: SCTID:332807009 xref: Wikipedia:Short_bone is_a: UBERON:0001474 {source="NCIT"} ! bone element property_value: editor_note "TODO - make subclass links" xsd:string [Term] id: UBERON:0013631 name: sesamoid element namespace: uberon def: "Ossicle that develops within bands of dense, regular connective tissue (e.g., tendons and ligaments). Sesamoids are generally located proximate to a bony prominence, over which the dense regular connective tissue wraps, and/or a joint or articulation." [PSPUB:0000169, VSAO:0000137] comment: Sesamoids are often endochondral replacement elements and in addition to bone tissue, may also be composed of articular cartilage, fibrocartilage, hyaline cartilage, and calcified cartilage. synonym: "sesamoid" EXACT [VSAO:0000137] xref: VSAO:0000137 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010911 {source="VSAO"} ! ossicle relationship: develops_in UBERON:0007846 {source="VSAO"} ! dense regular connective tissue relationship: only_in_taxon NCBITaxon:7742 ! Vertebrata [Term] id: UBERON:0013632 name: sesamoid cartilage namespace: uberon def: "A sesamoid element that is composed primarily of cartilage tissue." [OBOL:automatic] synonym: "cartilago sesamoidea" EXACT [FMA:55379] synonym: "sesamoid cartilage of cricopharyngeal ligament" EXACT [FMA:55379] xref: FMA:55379 is_a: UBERON:0007844 ! cartilage element is_a: UBERON:0013631 ! sesamoid element intersection_of: UBERON:0013631 ! sesamoid element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0013636 name: epithelium of intestinal villus namespace: uberon def: "An epithelium that is part of a intestinal villus." [OBOL:automatic] synonym: "intestinal villus epithelium" EXACT [FMA:63587] synonym: "villous epithelium" RELATED [] synonym: "villus epithelium" RELATED [] xref: FMA:63587 is_a: UBERON:0001902 ! epithelium of small intestine intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001213 ! intestinal villus relationship: part_of UBERON:0001213 ! intestinal villus relationship: part_of UBERON:0001902 {source="FMA"} ! epithelium of small intestine [Term] id: UBERON:0013685 name: foramen of skull namespace: uberon def: "Anatomical space that is an opening in a bone of the skull." [http://orcid.org/0000-0002-6601-2165, TAO:curator] synonym: "cranial conduit" NARROW [FMA:53165] synonym: "cranial foramen" NARROW [] synonym: "foramen of skull" EXACT [Wikipedia:Foramina_of_the_skull] synonym: "foramina of the skull" RELATED PLURAL [Wikipedia:Foramina_of_the_skull] xref: FMA:53165 xref: SCTID:276742007 xref: Wikipedia:Foramina_of_the_skull is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0005744 ! bone foramen intersection_of: part_of UBERON:0003129 ! skull relationship: part_of UBERON:0003129 ! skull [Term] id: UBERON:0013686 name: anatomical conduit space namespace: uberon def: "An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]." [FMA:9338, http://orcid.org/0000-0002-6601-2165] subset: common_anatomy synonym: "foramen space" NARROW [] xref: FMA:9338 is_a: UBERON:0000464 {source="FMA"} ! anatomical space relationship: connects UBERON:0000464 {cardinality="2"} ! anatomical space relationship: luminal_space_of UBERON:0004111 ! anatomical conduit relationship: part_of UBERON:0004111 ! anatomical conduit property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0013694 name: brain endothelium namespace: uberon def: "Vascular endothelium found in blood vessels of the blood-brain-barrier." [CALOHA:TS-0092] synonym: "cerebromicrovascular endothelium" RELATED [CALOHA:TS-0092] xref: BTO:0001852 xref: BTO:0003248 xref: CALOHA:TS-0092 is_a: UBERON:0001986 ! endothelium is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0000955 ! brain relationship: part_of UBERON:0000955 ! brain [Term] id: UBERON:0013695 name: colon endothelium namespace: uberon def: "Vascular endothelium found in colon blood vessels." [CALOHA:TS-0162] synonym: "colon endothelial cell" RELATED [CALOHA:TS-0162] synonym: "colon endothelial cells" RELATED [CALOHA:TS-0162] synonym: "colonic endothelial cell" RELATED [CALOHA:TS-0162] synonym: "colonic endothelium" RELATED [CALOHA:TS-0162] synonym: "colorectal endothelial cell" RELATED [CALOHA:TS-0162] synonym: "colorectal endothelium" RELATED [CALOHA:TS-0162] xref: CALOHA:TS-0162 is_a: UBERON:0000397 ! colonic epithelium is_a: UBERON:0001986 ! endothelium intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0001155 ! colon [Term] id: UBERON:0013697 name: exocrine pancreas epithelium namespace: uberon def: "Epithelium lining the exocrine pancreas." [CALOHA:TS-2108] synonym: "epithelium of exocrine pancreas" RELATED [CALOHA:TS-2108] synonym: "exocrine pancreas epithelial cell" RELATED [CALOHA:TS-2108] xref: CALOHA:TS-2108 is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000017 ! exocrine pancreas relationship: part_of UBERON:0000017 ! exocrine pancreas [Term] id: UBERON:0013700 name: axial musculature namespace: uberon def: "Musculature of the head and neck, spine, and ribs." [HP:0003327] xref: EHDAA2:0000159 xref: EMAPA:18166 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: attaches_to UBERON:0005944 ! axial skeleton plus cranial skeleton intersection_of: part_of UBERON:0013701 ! main body axis relationship: attaches_to UBERON:0005944 ! axial skeleton plus cranial skeleton relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0013701 ! main body axis [Term] id: UBERON:0013701 name: main body axis namespace: uberon def: "A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages." [https://orcid.org/0000-0002-6601-2165] subset: non_informative is_a: UBERON:0000475 ! organism subdivision relationship: only_in_taxon NCBITaxon:6072 ! Eumetazoa [Term] id: UBERON:0013702 name: body proper namespace: uberon def: "The region of the organism associated with the visceral organs." [AEO:0000103] subset: non_informative synonym: "body" RELATED [AEO:0000103] synonym: "whole body" RELATED [BTO:0001489] xref: AEO:0000103 xref: BTO:0001489 xref: EMAPA:36031 xref: FMA:231424 is_a: UBERON:0000475 {source="AEO"} ! organism subdivision relationship: part_of UBERON:0013701 ! main body axis property_value: UBPROP:0000001 "Cardinal body part, which consists of a maximal set of diverse subclasses of organ and organ part spatially associated with the vertebral column and ribcage. Examples: There is only one body proper[FMA:231424]." xsd:string {source="FMA:231424"} [Term] id: UBERON:0013703 name: integumentary projection namespace: uberon def: "Anatomical projection that is part of the integumentl system." [http://orcid.org/0000-0002-6601-2165] synonym: "skin projection" NARROW [] is_a: UBERON:0004529 ! anatomical projection is_a: UBERON:0006003 ! integumentary adnexa intersection_of: UBERON:0004529 ! anatomical projection intersection_of: part_of UBERON:0002416 ! integumental system [Term] id: UBERON:0013704 name: notochordal canal namespace: uberon def: "A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily." [http://medical-dictionary.thefreedictionary.com/notochordal+canal] synonym: "chordal canal" RELATED [] xref: FMA:293127 xref: NCIT:C34230 xref: UMLS:C1518428 {source="ncithesaurus:Notochordal_Canal"} is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: part_of UBERON:0006268 ! notochordal process relationship: part_of UBERON:0006268 ! notochordal process [Term] id: UBERON:0013727 name: notochordal fluid namespace: uberon def: "Fluid contained within the notochordal canal." [http://animaldiversity.org/accounts/Latimeria_chalumnae/, http://orcid.org/0000-0002-6601-2165] comment: Distinct feature of coelocanths synonym: "notochord fluid" EXACT [] synonym: "portion of notochordal fluid" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0006314 ! bodily fluid intersection_of: located_in UBERON:0013704 ! notochordal canal intersection_of: part_of UBERON:0036242 ! post-embryonic notochord relationship: located_in UBERON:0013704 ! notochordal canal relationship: part_of UBERON:0036242 ! post-embryonic notochord [Term] id: UBERON:0013748 name: ulnar metaphysis namespace: uberon def: "A metaphysis that is part of a ulna." [OBOL:automatic] subset: pheno_slim synonym: "metaphysis of ulna" EXACT [FMA:33767] xref: FMA:33767 is_a: UBERON:0001438 ! metaphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001438 ! metaphysis intersection_of: part_of UBERON:0001424 ! ulna relationship: part_of UBERON:0001010 {source="FMA"} ! diaphysis of ulna [Term] id: UBERON:0013749 name: metaphysis of humerus namespace: uberon def: "A metaphysis that is part of a metaphysis." [OBOL:automatic] subset: pheno_slim synonym: "diaphyseal end of humerus" EXACT [FMA:32830] synonym: "humeral metaphysis" EXACT [FMA:32830] xref: FMA:32830 is_a: UBERON:0001438 ! metaphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001438 ! metaphysis intersection_of: part_of UBERON:0000976 ! humerus relationship: part_of UBERON:0000976 ! humerus [Term] id: UBERON:0013750 name: metaphysis of tibia namespace: uberon def: "A metaphysis that is part of a tibia." [OBOL:automatic] subset: pheno_slim synonym: "tibial metaphysis" EXACT [FMA:33135] xref: EMAPA:37772 {source="MA:th"} xref: FMA:33135 xref: MA:0003106 is_a: UBERON:0001438 ! metaphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001438 ! metaphysis intersection_of: part_of UBERON:0000979 ! tibia relationship: part_of UBERON:0000979 ! tibia [Term] id: UBERON:0013751 name: metaphysis of radius namespace: uberon def: "A metaphysis that is part of a radius bone." [OBOL:automatic] subset: pheno_slim synonym: "radial metaphysis" EXACT [FMA:33789] xref: FMA:33789 is_a: UBERON:0001438 ! metaphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001438 ! metaphysis intersection_of: part_of UBERON:0001423 ! radius bone relationship: part_of UBERON:0001423 ! radius bone [Term] id: UBERON:0013752 name: diaphysis of metacarpal bone namespace: uberon def: "A diaphysis that is part of a metacarpal bone." [OBOL:automatic] synonym: "body of metacarpal" EXACT [FMA:33804] synonym: "corpus ossis metacarpi" EXACT [FMA:TA] synonym: "metacarpal bone diaphysis" EXACT [FMA:33804] synonym: "shaft of metacarpal" EXACT [FMA:33804] synonym: "shaft of metacarpal bone" EXACT [FMA:33804] xref: FMA:33804 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0002374 ! metacarpal bone relationship: part_of UBERON:0002374 ! metacarpal bone [Term] id: UBERON:0013753 name: distal epiphysis of metacarpal bone namespace: uberon def: "A distal epiphysis that is part of a metacarpal bone." [OBOL:automatic] subset: pheno_slim synonym: "caput ossis metacarpi" EXACT [FMA:TA] synonym: "distal end of metacarpal bone" EXACT [FMA:33798] synonym: "head of metacarpal bone" EXACT [FMA:33798] synonym: "lower end of metacarpal bone" EXACT [FMA:33798] xref: FMA:33798 is_a: UBERON:0004379 ! distal epiphysis is_a: UBERON:0004390 ! epiphysis of metacarpal bone intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0002374 ! metacarpal bone [Term] id: UBERON:0013754 name: integumentary system layer namespace: uberon def: "An organ component layer that is part of a integumental system." [OBOL:automatic] subset: non_informative synonym: "layer of skin" NARROW [] synonym: "skin layer" NARROW [] xref: SCTID:314820002 is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: part_of UBERON:0002416 ! integumental system relationship: part_of UBERON:0002416 ! integumental system [Term] id: UBERON:0013755 name: arterial blood namespace: uberon def: "A blood that is part of a artery." [OBOL:automatic] subset: pheno_slim synonym: "arterial blood" EXACT [FMA:83066] synonym: "blood in artery" EXACT [FMA:83066] synonym: "portion of arterial blood" EXACT [FMA:83066] xref: FMA:83066 is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood intersection_of: located_in UBERON:0001637 ! artery relationship: located_in UBERON:0001637 ! artery [Term] id: UBERON:0013756 name: venous blood namespace: uberon def: "A blood that is part of a vein." [OBOL:automatic] synonym: "blood in vein" EXACT [FMA:83067] synonym: "portion of venous blood" EXACT [FMA:83067] synonym: "venous blood" EXACT [FMA:83067] xref: FMA:83067 is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood intersection_of: located_in UBERON:0001638 ! vein relationship: located_in UBERON:0001638 ! vein [Term] id: UBERON:0013757 name: capillary blood namespace: uberon def: "A blood that is part of a capillary." [OBOL:automatic] synonym: "blood in capillary" EXACT [] synonym: "portion of blood in capillary" EXACT [FMA:263901] synonym: "portion of capillary blood" EXACT [] xref: FMA:263901 xref: NCIT:C32212 is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood intersection_of: located_in UBERON:0001982 ! capillary relationship: located_in UBERON:0001982 ! capillary [Term] id: UBERON:0013765 name: digestive system element namespace: uberon def: "Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: pheno_slim synonym: "digestive organ" EXACT [] synonym: "digestive system organ" EXACT [] xref: EMAPA:37843 {source="MA:th"} xref: SCTID:272627002 is_a: UBERON:0000062 ! organ intersection_of: UBERON:0000062 ! organ intersection_of: part_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0001007 ! digestive system [Term] id: UBERON:0013768 name: great vessel of heart namespace: uberon def: "Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart." [Wikipedia:Great_vessels] comment: Groupings may vary - typically pulmonary vessels and aorta and vena cavae subset: grouping_class synonym: "great vessel" BROAD [] synonym: "great vessel of thorax" EXACT [] xref: EMAPA:36460 xref: SCTID:304066000 xref: Wikipedia:Great_vessels is_a: UBERON:0001981 ! blood vessel [Term] id: UBERON:0013769 name: uterine lumen namespace: uberon def: "An organ cavity that is part of a uterus." [OBOL:automatic] synonym: "cavity of uterus" EXACT [FMA:17745] synonym: "uterine cavity" EXACT [FMA:17745] synonym: "uterine space" EXACT [] xref: EMAPA:36273 xref: FMA:17745 xref: Wikipedia:Uterine_cavity is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002558 ! organ cavity intersection_of: UBERON:0002558 ! organ cavity intersection_of: part_of UBERON:0000995 ! uterus relationship: part_of UBERON:0000995 ! uterus [Term] id: UBERON:0013774 name: diaphysis of metatarsal bone namespace: uberon def: "A diaphysis that is part of a metatarsal bone." [OBOL:automatic] subset: pheno_slim synonym: "diaphysis of metatarsal" EXACT [] synonym: "metatarsal bone diaphysis" EXACT [FMA:33826] synonym: "metatarsal diaphysis" EXACT [] synonym: "shaft of metatarsal bone" EXACT [FMA:33826] xref: FMA:33826 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004769 ! diaphysis intersection_of: UBERON:0004769 ! diaphysis intersection_of: part_of UBERON:0001448 ! metatarsal bone relationship: part_of UBERON:0001448 ! metatarsal bone [Term] id: UBERON:0014371 name: future telencephalon namespace: uberon def: "Embryonic structure that gives rise to the telencephalon." [ZFA:0000571, ZFA:curator] comment: paired anteriolateral division of the embryonic prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived[MP] synonym: "presumptive telencephalon" EXACT [ZFA:0000571] xref: EHDAA2:0004424 xref: EMAPA:36024 xref: TAO:0000571 xref: ZFA:0000571 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001893 ! telencephalon relationship: has_developmental_contribution_from UBERON:0003850 {evidence="definitional"} ! telencephalon neural crest relationship: has_potential_to_develop_into UBERON:0001893 ! telencephalon relationship: part_of UBERON:0006240 ! future forebrain [Term] id: UBERON:0014387 name: mesenchyme derived from neural crest namespace: uberon def: "Mesenchyme that develops_from the neural crest[Automatically generated definition]." [https://github.com/obophenotype/uberon/issues/248, OBOL:automatic] synonym: "mesenchyme from neural crest" EXACT [] synonym: "neural crest derived mesenchyme" EXACT [] synonym: "neural crest mesenchyme" EXACT [] xref: EMAPA:32735 xref: FMA:293883 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: develops_from UBERON:0002342 ! neural crest [Term] id: UBERON:0014388 name: kidney collecting duct epithelium namespace: uberon def: "The simple cuboidal epithelium lining the lumen of kidney collecting ducts." [MGI:anna, MP:0011843] subset: pheno_slim synonym: "collecting duct of renal tubule epithelium" EXACT [] synonym: "epithelium of collecting duct of renal tubule" EXACT [] synonym: "epithelium of renal collecting tubule" EXACT [] xref: EMAPA:37885 {source="MA:th"} is_a: UBERON:0000484 ! simple cuboidal epithelium is_a: UBERON:0004211 ! nephron epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001232 ! collecting duct of renal tubule relationship: contributes_to_morphology_of UBERON:0001232 ! collecting duct of renal tubule relationship: part_of UBERON:0001232 ! collecting duct of renal tubule property_value: UBPROP:0000008 "In mouse, the mature and differentiated CD epithelium comprises two unique cells types with principal cells responsible for vasopressin-regulated water reabsorption, and intercalated cells regulating acid-base homeostasis; injury to the epithelium is believed to cause epithelial cells to acquire mesenchymal characteristics via epithelial-mesenchymal transition (EMT), a process through which tubular epithelial cells may transform into interstitial fibroblasts and promote renal fibrosis" xsd:string [Term] id: UBERON:0014389 name: gustatory papilla of tongue namespace: uberon def: "A papilla that contain taste buds, including the fungiform, foliate, and circumvallate papillae." [MGI:smb, MP:0006256] synonym: "gustatory papilla" EXACT [] synonym: "gustatory papillae" RELATED PLURAL [] synonym: "taste papilla" EXACT [] synonym: "taste papillae" RELATED PLURAL [] xref: FMA:54822 is_a: UBERON:0001726 ! papilla of tongue intersection_of: UBERON:0001726 ! papilla of tongue intersection_of: has_part UBERON:0001727 ! taste bud relationship: has_part UBERON:0001727 ! taste bud [Term] id: UBERON:0014395 name: proximal mesopodial bone namespace: uberon def: "A proximal mesopodial endochondral element that is composed primarily of a bone tissue." [OBOL:automatic] is_a: UBERON:0003656 ! mesopodium bone is_a: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0017751 ! proximal mesopodial cartilage element [Term] id: UBERON:0014398 name: respiratory muscle namespace: uberon def: "Muscle that is part of the respiratory system." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim xref: MESH:D012132 is_a: UBERON:0003831 ! respiratory system muscle intersection_of: UBERON:0001630 ! muscle organ intersection_of: capable_of_part_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: capable_of_part_of GO:0007585 ! respiratory gaseous exchange by respiratory system relationship: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue property_value: IAO:0000232 "this class may be merged with 'respiratory system muscle'; check intercostals" xsd:string [Term] id: UBERON:0014399 name: sinusoidal space namespace: uberon def: "An anatomical space that is enclosed by a sinusoid." [OBOL:automatic] synonym: "lumen of sinusoid" EXACT [FMA:63133] synonym: "sinusoid lumen" EXACT [FMA:63133] xref: FMA:63133 is_a: UBERON:0010161 ! lumen of blood vessel intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0003909 ! sinusoid relationship: luminal_space_of UBERON:0003909 ! sinusoid relationship: part_of UBERON:0003909 ! sinusoid [Term] id: UBERON:0014400 name: hepatic sinusoidal space namespace: uberon def: "A sinusoidal space that is part of a hepatic sinusoid." [OBOL:automatic] synonym: "lumen of hepatic sinusoid" EXACT [FMA:262090] xref: FMA:262090 is_a: UBERON:0014399 ! sinusoidal space intersection_of: UBERON:0014399 ! sinusoidal space intersection_of: part_of UBERON:0001281 ! hepatic sinusoid relationship: part_of UBERON:0001281 ! hepatic sinusoid [Term] id: UBERON:0014401 name: renal venous blood vessel namespace: uberon def: "Any member of the network of tubes that return blood from the renal tissues to the systemic circulation." [MGI:csmith] subset: pheno_slim synonym: "kidney venous blood vessel" EXACT [MA:0002591] synonym: "kidney venous system" RELATED [EMAPA:31450] synonym: "venous blood vessel of kidney" EXACT [] xref: EMAPA:31450 xref: MA:0002591 is_a: UBERON:0003517 ! kidney blood vessel is_a: UBERON:0003920 ! venous blood vessel intersection_of: UBERON:0003920 ! venous blood vessel intersection_of: part_of UBERON:0002113 ! kidney property_value: UBPROP:0000012 "we follow MA and MP in distinguishing the venous blood vessel from the vein. The kidney cortex vein is not considered a renal vein, nor is the vasa recta" xsd:string {external_ontology="MA"} [Term] id: UBERON:0014402 name: sex-specific anatomical structure namespace: uberon def: "A part of the body present only in a specific gender." [AEO:0000174, AEO:JB] synonym: "gender-specific" EXACT [] synonym: "gender-specific anatomical structure" EXACT [AEO:0000174] synonym: "sex-specific" EXACT [] xref: AEO:0000174 xref: WBbt:0005752 is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: output_of GO:0007548 ! sex differentiation relationship: output_of GO:0007548 ! sex differentiation [Term] id: UBERON:0014403 name: male anatomical structure namespace: uberon def: "A part of the body present only in males." [AEO:0000175, AEO:JB] synonym: "male-specific" RELATED [WBbt:0005757] synonym: "male-specific structure" EXACT [] xref: AEO:0000175 xref: WBbt:0005757 is_a: UBERON:0014402 ! sex-specific anatomical structure intersection_of: UBERON:0014402 ! sex-specific anatomical structure intersection_of: part_of UBERON:0003101 ! male organism relationship: part_of UBERON:0003101 ! male organism [Term] id: UBERON:0014404 name: female anatomical structure namespace: uberon def: "A part of the body present only in females." [AEO:0000176, AEO:JB] xref: AEO:0000176 is_a: UBERON:0014402 ! sex-specific anatomical structure intersection_of: UBERON:0014402 ! sex-specific anatomical structure intersection_of: part_of UBERON:0003100 ! female organism relationship: part_of UBERON:0003100 ! female organism [Term] id: UBERON:0014451 name: tongue taste bud namespace: uberon def: "A taste bud that is located on the tongue, situated on a gustatory papilla." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "gustatory papilla taste bud" EXACT [] synonym: "gustatory papillae taste bud" EXACT [MP:0006260] is_a: UBERON:0001727 ! taste bud is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0014389 ! gustatory papilla of tongue [Term] id: UBERON:0014452 name: gustatory epithelium of tongue namespace: uberon def: "A gustatory epithelium that is part of a tongue." [OBOL:automatic] synonym: "lingual gustatory epithelium" EXACT [http://orcid.org/0000-0002-6601-2165] xref: BIRNLEX:4099 xref: UMLS:C1179150 {source="BIRNLEX:4099"} is_a: UBERON:0002926 ! gustatory epithelium is_a: UBERON:0003357 ! epithelium of tongue intersection_of: UBERON:0002926 ! gustatory epithelium intersection_of: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0014453 name: gustatory epithelium of palate namespace: uberon def: "A gustatory epithelium that is part of a roof of mouth." [OBOL:automatic] synonym: "palatal gustatory epithelium" EXACT [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0002424 ! oral epithelium is_a: UBERON:0002926 ! gustatory epithelium intersection_of: UBERON:0002926 ! gustatory epithelium intersection_of: part_of UBERON:0007375 ! roof of mouth relationship: part_of UBERON:0002424 ! oral epithelium relationship: part_of UBERON:0007375 ! roof of mouth [Term] id: UBERON:0014454 name: visceral abdominal adipose tissue namespace: uberon def: "Subcutaneous adipose tissue that is located in the peritoneal cavity." [CALOHA:paula, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/259, MGI:csmith] synonym: "abdominal fat" RELATED [BTO:0004041] synonym: "intra-abdominal adipose tissue" RELATED [] synonym: "intra-abdominal fat" RELATED [BTO:0004041] synonym: "organ fat" RELATED [BTO:0004041] synonym: "visceral adipose tissue" RELATED [BTO:0004041] synonym: "visceral fat" RELATED [BTO:0004041] xref: BTO:0004041 xref: CALOHA:TS-2405 is_a: UBERON:0007808 ! adipose tissue of abdominal region intersection_of: UBERON:0001013 ! adipose tissue intersection_of: bounding_layer_of UBERON:0002075 ! viscus intersection_of: located_in UBERON:0001179 ! peritoneal cavity intersection_of: part_of UBERON:0000916 ! abdomen relationship: bounding_layer_of UBERON:0002075 ! viscus relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cindyJax relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/paulacalipho relationship: located_in UBERON:0001179 ! peritoneal cavity relationship: part_of UBERON:0002075 ! viscus property_value: UBPROP:0000001 "Adipose tissue located inside the peritoneal cavity, packed in between internal organs and torso. An excess of visceral fat is known as central obesity, or belly fat, the pot belly or beer belly effect, in which the abdomen protrudes excessively[BTO:0004041]." xsd:string {source="BTO:0004041"} [Term] id: UBERON:0014455 name: subcutaneous abdominal adipose tissue namespace: uberon def: "Subcutaneous adipose tissue that is located in the abdominal region." [CALOHA:paula, http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/259, MGI:csmith] synonym: "abdominal subcutaneous adipose tissue" EXACT [] synonym: "subcutaneous abdominal fat" EXACT [] synonym: "subcutaneous fat of abdominal region" EXACT [] xref: CALOHA:TS-2406 is_a: UBERON:0002190 ! subcutaneous adipose tissue is_a: UBERON:0007808 ! adipose tissue of abdominal region intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0000916 ! abdomen intersection_of: part_of UBERON:0002072 ! hypodermis relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cindyJax relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/paulacalipho [Term] id: UBERON:0014463 name: cardiac ganglion namespace: uberon def: "Any of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery." [ISBN:0-683-40008-8, MP:0003685] synonym: "cardiac ganglia" RELATED PLURAL [] synonym: "cardiac ganglia set" EXACT [FMA:77582] synonym: "cardiac ganglion of Wrisberg" EXACT [] synonym: "ganglia cardiaca" EXACT [FMA:TA] synonym: "ganglion of Wrisberg" EXACT [FMA:77582] synonym: "Wrisberg ganglion" EXACT [MP:0003685] xref: EMAPA:36644 xref: FMA:77582 xref: SCTID:57098005 is_a: UBERON:0001808 ! parasympathetic ganglion intersection_of: UBERON:0001808 ! parasympathetic ganglion intersection_of: extends_fibers_into UBERON:0002008 ! cardiac nerve plexus relationship: extends_fibers_into UBERON:0002008 ! cardiac nerve plexus property_value: UBPROP:0000001 "Any of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery[http://medical-dictionary.thefreedictionary.com/cardiac+ganglion]." xsd:string {source="http://medical-dictionary.thefreedictionary.com/cardiac+ganglion"} [Term] id: UBERON:0014477 name: thoracic skeleton namespace: uberon def: "Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum." [https://orcid.org/0000-0002-6601-2165, Wikipedia:Rib_cage] subset: human_reference_atlas subset: pheno_slim synonym: "skeleton of thorax" EXACT [] synonym: "thoracic part of axial skeleton" EXACT [] synonym: "thoracic skeleton" EXACT [EHDAA2:0002013] xref: EHDAA2:0002013 xref: FMA:77169 xref: Wikipedia:Thoracic_skeleton is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010912 ! subdivision of skeleton relationship: part_of UBERON:0000915 ! thoracic segment of trunk relationship: part_of UBERON:0002090 ! postcranial axial skeleton property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014478 name: rib skeletal system namespace: uberon def: "Subdivision of skeletal system that consists of all ribs and rib joints in an organism. In many vertebrates this consists of the combination of the rib cage and all rib joints, but some vertebrates have ribs outside the thoracic rib cage." [https://orcid.org/0000-0002-6601-2165] synonym: "rib series" EXACT [TAO:0002100] synonym: "rib skeleton" RELATED [] synonym: "set of all ribs" RELATED [FMA:265719] xref: FMA:265719 xref: TAO:0002100 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000075 ! subdivision of skeletal system relationship: composed_primarily_of UBERON:0015019 ! rib endochondral element relationship: has_part UBERON:0003252 ! thoracic rib cage relationship: part_of UBERON:0011138 ! postcranial axial skeletal system property_value: RO:0002161 NCBITaxon:7778 {source="Wikipedia"} [Term] id: UBERON:0014483 name: distal phalanx of digit 1 namespace: uberon def: "A distal phalanx that is part of a digit 1 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 1 distal phalanx" EXACT [PHENOSCAPE:wd] synonym: "digit I P3" RELATED [] synonym: "distal phalanx of digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of first digit" EXACT [] synonym: "first distal phalanx" RELATED [] is_a: UBERON:0004300 ! distal phalanx intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0006048 ! digit 1 relationship: part_of UBERON:0006048 ! digit 1 relationship: part_of UBERON:5106048 ! digit 1 digitopodial skeleton [Term] id: UBERON:0014484 name: distal phalanx of digit 2 namespace: uberon def: "A distal phalanx that is part of a digit 2 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "2nd digit distal phalanx" EXACT [] synonym: "digit 2 distal phalanx" EXACT [PHENOSCAPE:wd] synonym: "digit II P3" RELATED [] synonym: "distal phalanx of 2nd digit" EXACT [] synonym: "distal phalanx of digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of index digit" EXACT [] synonym: "distal phalanx of second digit" EXACT [] synonym: "second digit distal phalanx" EXACT [] synonym: "second distal phalanx" EXACT [] is_a: UBERON:0004300 ! distal phalanx intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0006049 ! digit 2 relationship: part_of UBERON:0006049 ! digit 2 relationship: part_of UBERON:5106049 ! digit 2 digitopodial skeleton [Term] id: UBERON:0014485 name: distal phalanx of digit 3 namespace: uberon def: "A distal phalanx that is part of a digit 3. In odd-toes ungulates (Perissodactyla e.g. horses) this is called the coffin bone. In even-toed ungulates (Artiodactyla e.g cattle) this is associated with the medial claw." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Coffin_bone, Wikipedia:Equine_forelimb_anatomy#Distal_phalanx] synonym: "3rd digit distal phalanx" EXACT [] synonym: "coffin bone" NARROW [NCBITaxon:9787] synonym: "digit 3 distal phalanx" EXACT [PHENOSCAPE:wd] synonym: "digit III P3" RELATED [] synonym: "distal phalanx of 3rd digit" EXACT [] synonym: "distal phalanx of digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of middle digit" EXACT [] synonym: "distal phalanx of third digit" EXACT [] synonym: "equine 3rd phalanx of digit 3" EXACT [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "equine distal phalanx" EXACT [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "medial claw of artiodactyl" NARROW [NCBITaxon:91561] synonym: "medial claw of ruminant hoof" NARROW [NCBITaxon:91561] synonym: "medial ungual phalanx of artiodactyl" NARROW [NCBITaxon:91561] synonym: "pedal bone" NARROW [NCBITaxon:9787] synonym: "third digit distal phalanx" EXACT [] synonym: "third distal phalanx" EXACT [] xref: SCTID:370666003 xref: SCTID:370671005 xref: SCTID:410030004 xref: Wikipedia:Coffin_bone is_a: UBERON:0004300 ! distal phalanx intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0006050 ! digit 3 relationship: part_of UBERON:0006050 ! digit 3 relationship: part_of UBERON:5106050 ! digit 3 digitopodial skeleton property_value: UBPROP:0000008 "the bottommost bone in the equine leg and is encased by the hoof capsule. The distal phalanx articulates with both the middle phalanx and the distal sesamoid, forming the distal interphalangeal joint[Wikipedia:Coffin_bone]" xsd:string {source="Wikipedia:Coffin_bone", taxon="NCBITaxon:9788"} [Term] id: UBERON:0014486 name: distal phalanx of digit 4 namespace: uberon def: "A distal phalanx that is part of a digit 4 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "4th digit distal phalanx" EXACT [] synonym: "digit 4 distal phalanx" EXACT [PHENOSCAPE:wd] synonym: "digit IV P3" RELATED [] synonym: "distal phalanx of 4th digit" EXACT [] synonym: "distal phalanx of digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of fourth digit" EXACT [] synonym: "distal phalanx of ring digit" EXACT [] synonym: "fourth digit distal phalanx" EXACT [] synonym: "fourth distal phalanx" EXACT [] synonym: "lateral claw of artiodactyl" NARROW [NCBITaxon:91561] synonym: "lateral claw of ruminant hoof" NARROW [NCBITaxon:91561] synonym: "lateral ungual phalanx of artiodactyl" NARROW [NCBITaxon:91561] xref: SCTID:370667007 xref: SCTID:370670006 is_a: UBERON:0004300 ! distal phalanx intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0006051 ! digit 4 relationship: part_of UBERON:0006051 ! digit 4 relationship: part_of UBERON:5106051 ! digit 4 digitopodial skeleton [Term] id: UBERON:0014487 name: distal phalanx of digit 5 namespace: uberon def: "A distal phalanx that is part of a digit 5 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "5th digit distal phalanx" EXACT [] synonym: "digit 5 distal phalanx" EXACT [PHENOSCAPE:wd] synonym: "digit V P3" RELATED [] synonym: "distal phalanx of 5th digit" EXACT [] synonym: "distal phalanx of digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal phalanx of fifth digit" EXACT [] synonym: "distal phalanx of little digit" EXACT [] synonym: "fifth digit distal phalanx" EXACT [] synonym: "fifth distal phalanx" EXACT [] is_a: UBERON:0004300 ! distal phalanx intersection_of: UBERON:0004300 ! distal phalanx intersection_of: part_of UBERON:0006052 ! digit 5 relationship: part_of UBERON:0006052 ! digit 5 relationship: part_of UBERON:5106052 ! digit 5 digitopodial skeleton [Term] id: UBERON:0014488 name: middle phalanx of digit 2 namespace: uberon def: "A middle phalanx that is part of a digit 2 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "2nd digit intermediate phalanx" EXACT [] synonym: "2nd digit middle phalanx" EXACT [] synonym: "2nd digit of intermediate phalanx" EXACT [] synonym: "2nd digit of middle phalanx" EXACT [] synonym: "digit 2 intermediate phalanx" EXACT [] synonym: "digit 2 middle phalanx" EXACT [] synonym: "digit II P2" RELATED [] synonym: "intermediate phalanx of 2nd digit" EXACT [] synonym: "intermediate phalanx of digit 2" EXACT [] synonym: "intermediate phalanx of second digit" EXACT [] synonym: "middle phalanx of 2nd digit" EXACT [] synonym: "middle phalanx of digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of index digit" EXACT [] synonym: "middle phalanx of second digit" EXACT [] synonym: "second digit intermediate phalanx" EXACT [] synonym: "second digit middle phalanx" EXACT [] synonym: "second middle phalanx" EXACT [] is_a: UBERON:0004301 ! middle phalanx intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0006049 ! digit 2 relationship: part_of UBERON:0006049 ! digit 2 relationship: part_of UBERON:5106049 ! digit 2 digitopodial skeleton [Term] id: UBERON:0014489 name: middle phalanx of digit 3 namespace: uberon def: "A middle phalanx that is part of a digit 3 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "3rd digit intermediate phalanx" EXACT [] synonym: "3rd digit middle phalanx" EXACT [] synonym: "3rd digit of intermediate phalanx" EXACT [] synonym: "3rd digit of middle phalanx" EXACT [] synonym: "digit 3 intermediate phalanx" EXACT [] synonym: "digit 3 middle phalanx" EXACT [] synonym: "digit III P2" RELATED [] synonym: "intermediate phalanx of 3rd digit" EXACT [] synonym: "intermediate phalanx of digit 3" EXACT [] synonym: "intermediate phalanx of third digit" EXACT [] synonym: "middle phalanx of 3rd digit" EXACT [] synonym: "middle phalanx of digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of middle digit" EXACT [] synonym: "middle phalanx of third digit" EXACT [] synonym: "third digit intermediate phalanx" EXACT [] synonym: "third digit middle phalanx" EXACT [] synonym: "third middle phalanx" EXACT [] xref: SCTID:370676000 xref: SCTID:370730008 is_a: UBERON:0004301 ! middle phalanx intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0006050 ! digit 3 relationship: part_of UBERON:0006050 ! digit 3 relationship: part_of UBERON:5106050 ! digit 3 digitopodial skeleton [Term] id: UBERON:0014490 name: middle phalanx of digit 4 namespace: uberon def: "A middle phalanx that is part of a digit 4 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "4th digit intermediate phalanx" EXACT [] synonym: "4th digit middle phalanx" EXACT [] synonym: "4th digit of intermediate phalanx" EXACT [] synonym: "4th digit of middle phalanx" EXACT [] synonym: "digit 4 intermediate phalanx" EXACT [] synonym: "digit 4 middle phalanx" EXACT [] synonym: "digit IV P2" RELATED [] synonym: "fourth digit intermediate phalanx" EXACT [] synonym: "fourth digit middle phalanx" EXACT [] synonym: "fourth middle phalanx" EXACT [] synonym: "intermediate phalanx of 4th digit" EXACT [] synonym: "intermediate phalanx of digit 4" EXACT [] synonym: "intermediate phalanx of fourth digit" EXACT [] synonym: "middle phalanx of 4th digit" EXACT [] synonym: "middle phalanx of digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of fourth digit" EXACT [] synonym: "middle phalanx of ring digit" EXACT [] xref: SCTID:370675001 is_a: UBERON:0004301 ! middle phalanx intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0006051 ! digit 4 relationship: part_of UBERON:0006051 ! digit 4 relationship: part_of UBERON:5106051 ! digit 4 digitopodial skeleton [Term] id: UBERON:0014491 name: middle phalanx of digit 5 namespace: uberon def: "A middle phalanx that is part of a digit 5 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "5th digit intermediate phalanx" EXACT [] synonym: "5th digit middle phalanx" EXACT [] synonym: "5th digit of intermediate phalanx" EXACT [] synonym: "5th digit of middle phalanx" EXACT [] synonym: "digit 5 intermediate phalanx" EXACT [] synonym: "digit 5 middle phalanx" EXACT [] synonym: "digit V P2" RELATED [] synonym: "fifth digit intermediate phalanx" EXACT [] synonym: "fifth digit middle phalanx" EXACT [] synonym: "fifth middle phalanx" EXACT [] synonym: "intermediate phalanx of 5th digit" EXACT [] synonym: "intermediate phalanx of digit 5" EXACT [] synonym: "intermediate phalanx of fifth digit" EXACT [] synonym: "middle phalanx of 5th digit" EXACT [] synonym: "middle phalanx of digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "middle phalanx of fifth digit" EXACT [] synonym: "middle phalanx of little digit" EXACT [] is_a: UBERON:0004301 ! middle phalanx intersection_of: UBERON:0004301 ! middle phalanx intersection_of: part_of UBERON:0006052 ! digit 5 relationship: part_of UBERON:0006052 ! digit 5 relationship: part_of UBERON:5106052 ! digit 5 digitopodial skeleton [Term] id: UBERON:0014501 name: proximal phalanx of digit 1 namespace: uberon def: "A proximal phalanx that is part of a autopod digit 1 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "digit I P1" EXACT [] synonym: "digit I-1" EXACT [PHENOSCAPE:wd] synonym: "first proximal phalanx of autopod" EXACT [] synonym: "proximal phalanx of digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of first digit of autopod" EXACT [] is_a: UBERON:0004302 ! proximal phalanx intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0006048 ! digit 1 relationship: part_of UBERON:0006048 ! digit 1 relationship: part_of UBERON:5106048 ! digit 1 digitopodial skeleton [Term] id: UBERON:0014502 name: proximal phalanx of digit 2 namespace: uberon def: "A proximal phalanx that is part of a autopod digit 2 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "2nd digit of autopod proximal phalanx" EXACT [] synonym: "2nd digit proximal phalanx" EXACT [] synonym: "autopod digit 2 proximal phalanx" EXACT [] synonym: "digit II-1" EXACT [PHENOSCAPE:wd] synonym: "digit IU P1" EXACT [] synonym: "proximal phalanx of 2nd digit" EXACT [] synonym: "proximal phalanx of 2nd digit of autopod" EXACT [] synonym: "proximal phalanx of digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of index digit" EXACT [] synonym: "proximal phalanx of second digit" EXACT [] synonym: "proximal phalanx of second digit of autopod" EXACT [] synonym: "second digit proximal phalanx" EXACT [] synonym: "second proximal phalanx of autopod" EXACT [] is_a: UBERON:0004302 ! proximal phalanx intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0006049 ! digit 2 relationship: part_of UBERON:0006049 ! digit 2 relationship: part_of UBERON:5106049 ! digit 2 digitopodial skeleton [Term] id: UBERON:0014503 name: proximal phalanx of digit 3 namespace: uberon def: "A proximal phalanx that is part of a autopod digit 3 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "3rd digit of autopod proximal phalanx" EXACT [] synonym: "3rd digit proximal phalanx" EXACT [] synonym: "autopod digit 3 proximal phalanx" EXACT [] synonym: "digit III P1" EXACT [] synonym: "digit III-1" EXACT [PHENOSCAPE:wd] synonym: "proximal phalanx of 3rd digit" EXACT [] synonym: "proximal phalanx of 3rd digit of autopod" EXACT [] synonym: "proximal phalanx of digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of middle digit" EXACT [] synonym: "proximal phalanx of third digit" EXACT [] synonym: "proximal phalanx of third digit of autopod" EXACT [] synonym: "third digit proximal phalanx" EXACT [] synonym: "third proximal phalanx of autopod" EXACT [] xref: SCTID:370732000 xref: SCTID:370733005 is_a: UBERON:0004302 ! proximal phalanx intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0006050 ! digit 3 relationship: part_of UBERON:0006050 ! digit 3 relationship: part_of UBERON:5106050 ! digit 3 digitopodial skeleton [Term] id: UBERON:0014504 name: proximal phalanx of digit 4 namespace: uberon def: "A proximal phalanx that is part of a autopod digit 4 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "4th digit of autopod proximal phalanx" EXACT [] synonym: "4th digit proximal phalanx" EXACT [] synonym: "autopod digit 4 proximal phalanx" EXACT [] synonym: "digit IV P1" EXACT [] synonym: "digit IV-1" EXACT [PHENOSCAPE:wd] synonym: "fourth digit proximal phalanx" EXACT [] synonym: "fourth proximal phalanx of autopod" EXACT [] synonym: "proximal phalanx of 4th digit" EXACT [] synonym: "proximal phalanx of 4th digit of autopod" EXACT [] synonym: "proximal phalanx of digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of fourth digit" EXACT [] synonym: "proximal phalanx of fourth digit of autopod" EXACT [] synonym: "proximal phalanx of ring digit" EXACT [] is_a: UBERON:0004302 ! proximal phalanx intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0006051 ! digit 4 relationship: part_of UBERON:0006051 ! digit 4 relationship: part_of UBERON:5106051 ! digit 4 digitopodial skeleton [Term] id: UBERON:0014505 name: proximal phalanx of digit 5 namespace: uberon def: "A proximal phalanx that is part of a autopod digit 5 [Automatically generated definition]." [http://orcid.org/0000-0002-6601-2165] synonym: "5th digit of autopod proximal phalanx" EXACT [] synonym: "5th digit proximal phalanx" EXACT [] synonym: "autopod digit 5 proximal phalanx" EXACT [] synonym: "digit V P1" EXACT [] synonym: "digit V-1" EXACT [PHENOSCAPE:wd] synonym: "fifth digit proximal phalanx" EXACT [] synonym: "fifth proximal phalanx of autopod" EXACT [] synonym: "proximal phalanx of 5th digit" EXACT [] synonym: "proximal phalanx of 5th digit of autopod" EXACT [] synonym: "proximal phalanx of digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "proximal phalanx of fifth digit" EXACT [] synonym: "proximal phalanx of fifth digit of autopod" EXACT [] synonym: "proximal phalanx of little digit" EXACT [] is_a: UBERON:0004302 ! proximal phalanx intersection_of: UBERON:0004302 ! proximal phalanx intersection_of: part_of UBERON:0006052 ! digit 5 relationship: part_of UBERON:0006052 ! digit 5 relationship: part_of UBERON:5106052 ! digit 5 digitopodial skeleton [Term] id: UBERON:0014506 name: distal interphalangeal joint of digit 3 namespace: uberon def: "A distal inter-phalangeal joint that is part of the 3rd digit." [http://orcid.org/0000-0002-6601-2165] synonym: "coffin joint" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "distal interphalangeal joint 3" RELATED [] synonym: "distal interphalangeal joint of digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "equine distal interphalangeal joint" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "equine second interphalangeal joint of limb digit III" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] xref: NCIT:C102292 xref: SCTID:196392002 xref: SCTID:370892008 is_a: UBERON:0009768 ! distal interphalangeal joint intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0006050 ! digit 3 relationship: part_of UBERON:0006050 ! digit 3 property_value: UBPROP:0000008 "In Equidae, this is known as the coffin joint, and is the articulation between the short pastern bone (P2) and the coffin bone (P3 / distal phalanx)" xsd:string [Term] id: UBERON:0014507 name: distal interphalangeal joint of pedal digit 3 namespace: uberon def: "A distal inter-phalangeal joint that is part of the 3rd pedal digit." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "distal interphalangeal joint of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal interphalangeal joint of third digit of foot" EXACT [FMA:35375] synonym: "distal interphalangeal joint of third toe" EXACT [FMA:35375] synonym: "equine distal interphalangeal joint of hindlimb" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "hindlimb coffin joint" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] xref: FMA:35375 xref: SCTID:361880001 is_a: UBERON:0007726 ! interphalangeal joint of pedal digit 3 is_a: UBERON:0014506 ! distal interphalangeal joint of digit 3 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003633 ! pedal digit 3 [Term] id: UBERON:0014508 name: distal interphalangeal joint of manual digit 3 namespace: uberon def: "A distal inter-phalangeal joint that is part of the 3rd manual digit." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "distal interphalangeal joint of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal interphalangeal joint of middle finger" EXACT [FMA:35337] synonym: "equine distal interphalangeal joint of forelimb" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "equine second interphalangeal joint of forelimb digit III" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] synonym: "forelimb coffin joint" NARROW [https://orcid.org/0000-0002-6601-2165, NCBITaxon:9788] xref: FMA:35337 xref: SCTID:361854002 xref: SCTID:370683007 is_a: UBERON:0007730 ! interphalangeal joint of manual digit 3 is_a: UBERON:0014506 ! distal interphalangeal joint of digit 3 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003623 ! manual digit 3 [Term] id: UBERON:0014530 name: white matter lamina of neuraxis namespace: uberon synonym: "lamina of neuraxis" BROAD [FMA:83856] synonym: "neuraxis lamina" BROAD [FMA:83856] xref: FMA:83856 is_a: UBERON:0011215 ! central nervous system cell part cluster is_a: UBERON:0022303 ! nervous system cell part layer intersection_of: UBERON:0022303 ! nervous system cell part layer intersection_of: part_of UBERON:0002316 ! white matter relationship: part_of UBERON:0002316 ! white matter [Term] id: UBERON:0014532 name: white matter lamina of cerebral hemisphere namespace: uberon synonym: "cerebral hemisphere lamina" BROAD [FMA:67951] synonym: "lamina of cerebral hemisphere" BROAD [FMA:67951] xref: FMA:67951 is_a: UBERON:0014530 ! white matter lamina of neuraxis intersection_of: UBERON:0014530 ! white matter lamina of neuraxis intersection_of: part_of UBERON:0001869 ! cerebral hemisphere relationship: part_of UBERON:0001869 ! cerebral hemisphere [Term] id: UBERON:0014610 name: thoracic spinal cord ventral horn namespace: uberon def: "A ventral horn of spinal cord that is part of a thoracic spinal cord." [OBOL:automatic] subset: human_reference_atlas synonym: "thoracic spinal cord anterior horn" RELATED [BIRNLEX:1410] synonym: "thoracic spinal cord ventral horn" EXACT HUMAN_PREFERRED [BIRNLEX:1410] xref: BIRNLEX:1410 xref: SCTID:367876000 xref: UMLS:C0228632 {source="BIRNLEX:1410"} xref: UMLS:C1288552 {source="BIRNLEX:1410"} is_a: UBERON:0002257 ! ventral horn of spinal cord intersection_of: UBERON:0002257 ! ventral horn of spinal cord intersection_of: part_of UBERON:0003038 ! thoracic spinal cord relationship: part_of UBERON:0003038 ! thoracic spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014613 name: cervical spinal cord gray matter namespace: uberon def: "A gray matter of spinal cord that is part of a cervical spinal cord." [OBOL:automatic] subset: human_reference_atlas synonym: "cervical spinal cord gray matter" EXACT HUMAN_PREFERRED [BIRNLEX:1521] xref: BIRNLEX:1521 xref: SCTID:362438009 xref: UMLS:C0228610 {source="BIRNLEX:1521"} is_a: UBERON:0002315 ! gray matter of spinal cord intersection_of: UBERON:0002315 ! gray matter of spinal cord intersection_of: part_of UBERON:0002726 ! cervical spinal cord relationship: part_of UBERON:0002726 ! cervical spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014614 name: cervical spinal cord white matter namespace: uberon def: "A white matter of spinal cord that is part of a cervical spinal cord." [OBOL:automatic] subset: human_reference_atlas synonym: "cervical spinal cord white matter" EXACT HUMAN_PREFERRED [BIRNLEX:1531] xref: BIRNLEX:1531 xref: SCTID:174829001 xref: UMLS:C0228616 {source="BIRNLEX:1531"} is_a: UBERON:0002318 ! white matter of spinal cord intersection_of: UBERON:0002318 ! white matter of spinal cord intersection_of: part_of UBERON:0002726 ! cervical spinal cord relationship: part_of UBERON:0002726 ! cervical spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014621 name: cervical spinal cord ventral horn namespace: uberon def: "A ventral horn of spinal cord that is part of a cervical spinal cord." [OBOL:automatic] subset: human_reference_atlas synonym: "cervical spinal cord anterior horn" RELATED [BIRNLEX:1680] synonym: "cervical spinal cord ventral horn" EXACT HUMAN_PREFERRED [BIRNLEX:1680] xref: BIRNLEX:1680 xref: SCTID:174363005 xref: UMLS:C0228615 {source="BIRNLEX:1680"} xref: UMLS:C1278740 {source="BIRNLEX:1680"} is_a: UBERON:0002257 ! ventral horn of spinal cord intersection_of: UBERON:0002257 ! ventral horn of spinal cord intersection_of: part_of UBERON:0002726 ! cervical spinal cord relationship: part_of UBERON:0002726 ! cervical spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014636 name: thoracic spinal cord gray matter namespace: uberon def: "A gray matter of spinal cord that is part of a thoracic spinal cord." [OBOL:automatic] subset: human_reference_atlas synonym: "thoracic spinal cord gray matter" EXACT HUMAN_PREFERRED [BIRNLEX:980] xref: BIRNLEX:980 xref: SCTID:362441000 xref: UMLS:C0228627 {source="BIRNLEX:980"} is_a: UBERON:0002315 ! gray matter of spinal cord intersection_of: UBERON:0002315 ! gray matter of spinal cord intersection_of: part_of UBERON:0003038 ! thoracic spinal cord relationship: part_of UBERON:0003038 ! thoracic spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014637 name: thoracic spinal cord white matter namespace: uberon def: "A white matter of spinal cord that is part of a thoracic spinal cord." [OBOL:automatic] subset: human_reference_atlas synonym: "thoracic spinal cord white matter" EXACT HUMAN_PREFERRED [BIRNLEX:999] xref: BIRNLEX:999 xref: SCTID:367881009 xref: UMLS:C0228633 {source="BIRNLEX:999"} xref: UMLS:C1288557 {source="BIRNLEX:999"} is_a: UBERON:0002318 ! white matter of spinal cord intersection_of: UBERON:0002318 ! white matter of spinal cord intersection_of: part_of UBERON:0003038 ! thoracic spinal cord relationship: part_of UBERON:0003038 ! thoracic spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014649 name: white matter of medulla oblongata namespace: uberon def: "A white matter that is part of a medulla oblongata." [OBOL:automatic] synonym: "medullary white matter" RELATED [BAMS:mw] synonym: "substantia alba medullae oblongatae" EXACT [FMA:TA] synonym: "white matter of medulla" EXACT [FMA:83944] synonym: "white substance of medulla" EXACT [FMA:83944] xref: BAMS:mw xref: BIRNLEX:1024 xref: BIRNLEX:1414 xref: FMA:83944 xref: neuronames:778 is_a: UBERON:0014891 ! brainstem white matter is_a: UBERON:0019262 ! white matter of myelencephalon intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001896 ! medulla oblongata relationship: part_of UBERON:0001896 ! medulla oblongata [Term] id: UBERON:0014668 name: distal interphalangeal joint of manual digit 2 namespace: uberon subset: pheno_slim synonym: "distal interphalangeal joint of index finger" EXACT [FMA:35334] synonym: "distal interphalangeal joint of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:35334 xref: SCTID:361852003 is_a: UBERON:0007729 ! interphalangeal joint of manual digit 2 is_a: UBERON:0014677 ! distal interphalangeal joint of digit 2 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003622 ! manual digit 2 [Term] id: UBERON:0014670 name: distal interphalangeal joint of manual digit 4 namespace: uberon subset: pheno_slim synonym: "distal interphalangeal joint of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal interphalangeal joint of ring finger" EXACT [FMA:35340] xref: FMA:35340 xref: SCTID:361856000 is_a: UBERON:0007731 ! interphalangeal joint of manual digit 4 is_a: UBERON:0014679 ! distal interphalangeal joint of digit 4 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003624 ! manual digit 4 [Term] id: UBERON:0014671 name: distal interphalangeal joint of manural digit 5 namespace: uberon synonym: "distal interphalangeal joint of little finger" EXACT [FMA:35343] synonym: "distal interphalangeal joint of manural digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:35343 xref: SCTID:361858004 is_a: UBERON:0007732 ! interphalangeal joint of manual digit 5 is_a: UBERON:0014680 ! distal interphalangeal joint of digit 5 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003625 ! manual digit 5 [Term] id: UBERON:0014672 name: distal interphalangeal joint of pedal digit 2 namespace: uberon subset: pheno_slim synonym: "distal interphalangeal joint of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal interphalangeal joint of second digit of foot" EXACT [FMA:35369] synonym: "distal interphalangeal joint of second toe" EXACT [FMA:35369] xref: FMA:35369 xref: SCTID:361878007 is_a: UBERON:0007725 ! interphalangeal joint of pedal digit 2 is_a: UBERON:0014677 ! distal interphalangeal joint of digit 2 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003632 ! pedal digit 2 [Term] id: UBERON:0014674 name: distal interphalangeal joint of pedal digit 4 namespace: uberon subset: pheno_slim synonym: "distal interphalangeal joint of fourth digit of foot" EXACT [FMA:35387] synonym: "distal interphalangeal joint of fourth toe" EXACT [FMA:35387] synonym: "distal interphalangeal joint of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:35387 xref: SCTID:361882009 is_a: UBERON:0007727 ! interphalangeal joint of pedal digit 4 is_a: UBERON:0014679 ! distal interphalangeal joint of digit 4 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003634 ! pedal digit 4 [Term] id: UBERON:0014675 name: distal interphalangeal joint of pedal digit 5 namespace: uberon subset: pheno_slim synonym: "distal interphalangeal joint of fifth digit of foot" EXACT [FMA:35393] synonym: "distal interphalangeal joint of fifth toe" EXACT [FMA:35393] synonym: "distal interphalangeal joint of little toe" EXACT [FMA:35393] synonym: "distal interphalangeal joint of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: FMA:35393 xref: SCTID:361884005 is_a: UBERON:0007728 ! interphalangeal joint of pedal digit 5 is_a: UBERON:0014680 ! distal interphalangeal joint of digit 5 intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0003635 ! pedal digit 5 [Term] id: UBERON:0014677 name: distal interphalangeal joint of digit 2 namespace: uberon def: "A distal interphalangeal joint that is part of a digit 2." [OBOL:automatic] synonym: "distal interphalangeal joint 2" RELATED [] synonym: "distal interphalangeal joint of digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: NCIT:C102291 is_a: UBERON:0009768 ! distal interphalangeal joint intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0006049 ! digit 2 relationship: part_of UBERON:0006049 ! digit 2 property_value: editor_note "check whether NCITA classes belong with hand or generic autopod" xsd:string [Term] id: UBERON:0014679 name: distal interphalangeal joint of digit 4 namespace: uberon def: "A distal interphalangeal joint that is part of a digit 4." [OBOL:automatic] synonym: "distal interphalangeal joint 4" RELATED [] synonym: "distal interphalangeal joint of digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: NCIT:C102293 is_a: UBERON:0009768 ! distal interphalangeal joint intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0006051 ! digit 4 relationship: part_of UBERON:0006051 ! digit 4 [Term] id: UBERON:0014680 name: distal interphalangeal joint of digit 5 namespace: uberon def: "A distal interphalangeal joint that is part of a digit 5." [OBOL:automatic] synonym: "distal interphalangeal joint 5" RELATED [] synonym: "distal interphalangeal joint of digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] xref: NCIT:C102294 is_a: UBERON:0009768 ! distal interphalangeal joint intersection_of: UBERON:0009768 ! distal interphalangeal joint intersection_of: part_of UBERON:0006052 ! digit 5 relationship: part_of UBERON:0006052 ! digit 5 [Term] id: UBERON:0014695 name: deep auricular artery namespace: uberon def: "The deep auricular artery often arises in common with the anterior tympanic artery. It ascends in the substance of the parotid gland, behind the temporomandibular articulation, pierces the cartilaginous or bony wall of the external acoustic meatus, and supplies its cuticular lining and the outer surface of the tympanic membrane. It gives a branch to the temporomandibular joint." [Wikipedia:Deep_auricular_artery] subset: human_reference_atlas xref: FMA:49689 xref: SCTID:147157007 xref: Wikipedia:Deep_auricular_artery is_a: UBERON:0009655 ! auricular artery intersection_of: UBERON:0009655 ! auricular artery intersection_of: part_of UBERON:0035551 ! deep vasculature relationship: branching_part_of UBERON:0001616 {source="FMA"} ! maxillary artery relationship: part_of UBERON:0001616 ! maxillary artery relationship: part_of UBERON:0035551 ! deep vasculature relationship: supplies UBERON:0010069 ! outer epithelial layer of tympanic membrane property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014699 name: extraembryonic venous system namespace: uberon def: "A venous system that overlaps a umbilical cord and is part of a entire extraembryonic component." [OBOL:automatic] xref: EHDAA2:0000479 xref: EMAPA:16374 xref: VHOG:0000282 is_a: UBERON:0004582 ! venous system is_a: UBERON:0014701 {source="VHOG"} ! extraembryonic vascular system intersection_of: UBERON:0004582 ! venous system intersection_of: overlaps UBERON:0002331 ! umbilical cord intersection_of: part_of UBERON:0016887 ! entire extraembryonic component [Term] id: UBERON:0014701 name: extraembryonic vascular system namespace: uberon def: "A vascular system that overlaps a umbilical cord and is part of a entire extraembryonic component." [OBOL:automatic] xref: EHDAA2:0000478 xref: EMAPA:16370 xref: VHOG:0001396 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0007798 ! vascular system intersection_of: UBERON:0007798 ! vascular system intersection_of: overlaps UBERON:0002331 ! umbilical cord intersection_of: part_of UBERON:0016887 ! entire extraembryonic component relationship: overlaps UBERON:0002331 ! umbilical cord relationship: part_of UBERON:0016887 ! entire extraembryonic component [Term] id: UBERON:0014702 name: frontonasal process epithelium namespace: uberon def: "An epithelium that is part of a frontonasal prominence." [OBOL:automatic] xref: EHDAA2:0004108 xref: EMAPA:32918 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0004066 ! frontonasal prominence relationship: develops_from UBERON:0000076 {source="EHDAA2"} ! external ectoderm relationship: part_of UBERON:0004066 ! frontonasal prominence [Term] id: UBERON:0014703 name: anal membrane ectodermal component namespace: uberon def: "A unilaminar epithelium that develops_from a ectoderm and is part of a anal region." [OBOL:automatic] xref: EHDAA2:0004019 xref: EMAPA:25040 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: develops_from UBERON:0000924 ! ectoderm intersection_of: part_of UBERON:0001353 ! anal region relationship: part_of UBERON:0001353 ! anal region [Term] id: UBERON:0014704 name: pleuroperitoneal canal lumen namespace: uberon def: "An anatomical space that is enclosed by a pleuroperitoneal canal." [OBOL:automatic] synonym: "pleuro-peritoneal canal cavity" EXACT [EMAPA:25034] xref: EHDAA2:0004736 xref: EMAPA:25034 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0006279 ! pleuroperitoneal canal relationship: develops_from UBERON:0002323 {source="EHDAA2"} ! coelemic cavity lumen relationship: luminal_space_of UBERON:0006279 ! pleuroperitoneal canal relationship: part_of UBERON:0006279 ! pleuroperitoneal canal [Term] id: UBERON:0014705 name: median lingual swelling epithelium namespace: uberon def: "An epithelium that is part of a median lingual swelling." [OBOL:automatic] synonym: "tuberculum impar epitheilium" RELATED [EMAPA:17188] xref: EHDAA2:0001085 xref: EMAPA:17188 is_a: UBERON:0000490 {source="EHDAA2"} ! unilaminar epithelium is_a: UBERON:0003929 ! digestive tract epithelium is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0005911 ! endo-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006756 ! median lingual swelling relationship: develops_from UBERON:0013156 {source="EHDAA2"} ! 1st arch mandibular endoderm relationship: part_of UBERON:0006756 ! median lingual swelling [Term] id: UBERON:0014706 name: primitive renal collecting duct system namespace: uberon synonym: "metanephros primitive collecting ducts" EXACT [EHDAA2:0001147] synonym: "primitive collecting duct" EXACT [EMAPA:17646] xref: EHDAA2:0001147 xref: EMAPA:17646 is_a: UBERON:0007501 {source="EHDAA2"} ! arborizing epithelial duct system is_a: UBERON:0012275 ! meso-epithelium relationship: develops_from UBERON:0000084 {source="EHDAA2"} ! ureteric bud [Term] id: UBERON:0014716 name: interlobular duct namespace: uberon def: "A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory." [ncithesaurus:Interlobular_Duct] subset: human_reference_atlas xref: NCIT:C32828 xref: UMLS:C1512857 xref: Wikipedia:Interlobular_ducts is_a: UBERON:0035050 ! excretory duct intersection_of: UBERON:0000058 ! duct intersection_of: connected_to UBERON:0009911 ! lobule intersection_of: part_of UBERON:0002384 ! connective tissue relationship: connected_to UBERON:0009911 ! lobule relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0002384 ! connective tissue property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014717 name: mucous acinus namespace: uberon def: "The secretory unit of a mucous gland. The acinar portion is composed of mucous secreting cells." [http://orcid.org/0000-0002-6601-2165, http://www.siumed.edu/~dking2/intro/glands.htm] synonym: "acinus of mucuous gland" EXACT [] synonym: "mucus acinus" EXACT [] xref: FMA:86278 is_a: UBERON:0011858 ! acinus of exocrine gland intersection_of: UBERON:0009842 ! glandular acinus intersection_of: part_of UBERON:0000414 ! mucous gland relationship: composed_primarily_of CL:0000319 ! mucus secreting cell relationship: part_of UBERON:0000414 ! mucous gland [Term] id: UBERON:0014719 name: intralobular duct namespace: uberon def: "A duct that is located within a lobule, with no more connective tissue intervening between ducts and secretory units (i.e., acini or tubules) than between adjacent secretory units. Intercalated and striated ducts are intralobular." [http://www.siumed.edu/~dking2/intro/glands.htm] subset: human_reference_atlas synonym: "intralobular ductule" RELATED [] xref: SCTID:205214009 is_a: UBERON:0000058 ! duct intersection_of: UBERON:0000058 ! duct intersection_of: part_of UBERON:0009911 ! lobule relationship: part_of UBERON:0009911 ! lobule property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0014720 name: interlobar duct namespace: uberon def: "A duct that is located between lobes, within conspicuous, thick connective tissue septa that separate lobes. All interlobar ducts are excretory." [http://www.siumed.edu/~dking2/intro/glands.htm] synonym: "intralobular ductule" RELATED [] is_a: UBERON:0035050 ! excretory duct intersection_of: UBERON:0000058 ! duct intersection_of: connects UBERON:0009912 ! anatomical lobe intersection_of: part_of UBERON:0002384 ! connective tissue relationship: connects UBERON:0009912 ! anatomical lobe relationship: part_of UBERON:0002384 ! connective tissue [Term] id: UBERON:0014762 name: fused metapodial bones 2-4 namespace: uberon def: "An element formed from the fusion of metapodium bones 2, 3 and 4 (i.e. either metatarsals 2-4 or metacarpals 3-4)." [http://orcid.org/0000-0002-6601-2165] synonym: "fused central metapodials" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "fused metapodials 2-4" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "metapodial 2+3+4" RELATED [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0013586 ! fused metapodial bones 3 and 4 intersection_of: UBERON:0003821 ! metapodium bone intersection_of: derived_from_ancestral_fusion_of UBERON:0013582 ! metapodium bone 2 intersection_of: derived_from_ancestral_fusion_of UBERON:0013583 ! metapodium bone 3 intersection_of: derived_from_ancestral_fusion_of UBERON:0013584 ! metapodium bone 4 relationship: derived_from_ancestral_fusion_of UBERON:0013582 ! metapodium bone 2 property_value: RO:0002175 NCBITaxon:51337 [Term] id: UBERON:0014763 name: fused metatarsal bones 2-4 namespace: uberon def: "An element formed from the fusion of metapodium bones 2, 3 and 4 in the pedal autopod." [http://orcid.org/0000-0002-6601-2165] synonym: "cannon bone" RELATED [NCBITaxon:51337] synonym: "fused central metatarsals" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "fused metatarsals 2-4" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "metatarsal 2+3+4" RELATED [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0013588 ! fused metatarsal bones 3 and 4 is_a: UBERON:0014762 ! fused metapodial bones 2-4 intersection_of: UBERON:0001448 ! metatarsal bone intersection_of: derived_from_ancestral_fusion_of UBERON:0003651 ! metatarsal bone of digit 2 intersection_of: derived_from_ancestral_fusion_of UBERON:0003652 ! metatarsal bone of digit 3 intersection_of: derived_from_ancestral_fusion_of UBERON:0003653 ! metatarsal bone of digit 4 relationship: derived_from_ancestral_fusion_of UBERON:0003651 ! metatarsal bone of digit 2 property_value: RO:0002175 NCBITaxon:51337 property_value: UBPROP:0000008 "The cannon bone of the 3-toed jerboa (jaculus jaculus) is the postnatal fusion of the 3 central metatarsals, which are distinct ossified elements prenatally" xsd:string {source="PMID:22135653", taxon="NCBITaxon:51337"} [Term] id: UBERON:0014765 name: crus of diaphragm namespace: uberon def: "The domain of the diaphragm that is located dorsally and attaches to the vertebrae and surrounds the esophagus and aorta." [PMID:23586979] comment: Classification notes: May be considered an external sphincter[PMID:8224664] synonym: "crura of the diaphragm" RELATED [Wikipedia:Crus_of_diaphragm] synonym: "crural diaphragm" EXACT [PMID:23586979] synonym: "crus of the diaphragm" RELATED [Wikipedia:Crus_of_diaphragm] synonym: "diaphragm crura" RELATED PLURAL [] synonym: "diaphragmatic crura" RELATED [Wikipedia:Crus_of_diaphragm] xref: EHDAA2:0000597 xref: EMAPA:17703 xref: SCTID:244668003 xref: VHOG:0001546 xref: Wikipedia:Crus_of_diaphragm is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000063 ! organ subunit relationship: attaches_to UBERON:0001130 ! vertebral column relationship: attaches_to UBERON:0006670 ! central tendon of diaphragm relationship: intersects_midsagittal_plane_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm relationship: part_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm [Term] id: UBERON:0014766 name: right crus of diaphragm namespace: uberon def: "A crus of diaphragm that is in_the_right_side_of a diaphragm." [OBOL:automatic] synonym: "crus dextrum (Diaphragma)" EXACT LATIN [FMA:58286, FMA:TA] synonym: "crus dextrum diaphragmatis" EXACT LATIN [FMA:58286, FMA:TA] synonym: "external sphincter of esophagus" EXACT [FMA:58286] synonym: "right crus of diaphragm" EXACT [FMA:58286] synonym: "right crus of lumbar part of diaphragm" EXACT [FMA:58286] xref: FMA:58286 xref: SCTID:362690009 is_a: UBERON:0014765 ! crus of diaphragm is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0014765 ! crus of diaphragm intersection_of: in_right_side_of UBERON:0001103 ! diaphragm relationship: in_right_side_of UBERON:0001103 ! diaphragm property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0014767 name: left crus of diaphragm namespace: uberon def: "A crus of diaphragm that is in_the_left_side_of a diaphragm." [OBOL:automatic] synonym: "crus sinistrum (Diaphragma)" EXACT LATIN [FMA:58287, FMA:TA] synonym: "crus sinistrum diaphragmatis" EXACT LATIN [FMA:58287, FMA:TA] synonym: "left crus of diaphragm" EXACT [FMA:58287] synonym: "left crus of lumbar part of diaphragm" EXACT [FMA:58287] xref: FMA:58287 xref: SCTID:244937004 is_a: UBERON:0014765 ! crus of diaphragm is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0014765 ! crus of diaphragm intersection_of: in_left_side_of UBERON:0001103 ! diaphragm relationship: in_left_side_of UBERON:0001103 ! diaphragm property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:0014775 name: prosomere namespace: uberon def: "A neuromere that is part of the presumptive forebrain." [http://orcid.org/0000-0002-6601-2165] synonym: "forebrain neuromere" EXACT [] synonym: "forebrain segment" BROAD [] synonym: "future prosencephalon" RELATED [] synonym: "segment of forebrain" BROAD [] xref: FMA:61996 is_a: UBERON:0004731 ! neuromere intersection_of: UBERON:0004731 ! neuromere intersection_of: part_of UBERON:0006240 ! future forebrain relationship: part_of UBERON:0006240 ! future forebrain [Term] id: UBERON:0014776 name: midbrain neuromere namespace: uberon def: "A neuromere that is part of the presumptive midbrain." [http://orcid.org/0000-0002-6601-2165] synonym: "future mesencephalon" RELATED [] synonym: "mesomere" BROAD [] synonym: "mesomere group" RELATED [EHDAA2:0004352] synonym: "mesomere of nervous system" EXACT [] synonym: "midbrain segment" BROAD [] synonym: "neuromere of mesomere group" EXACT [] synonym: "segment of midbrain" BROAD [] xref: EHDAA2:0004352 xref: FMA:61997 is_a: UBERON:0004731 ! neuromere intersection_of: UBERON:0004731 ! neuromere intersection_of: part_of UBERON:0009616 ! presumptive midbrain relationship: part_of UBERON:0009616 ! presumptive midbrain [Term] id: UBERON:0014777 name: spinal neuromere namespace: uberon def: "A neuromere that is part of the presumptive spinal cord." [http://orcid.org/0000-0002-6601-2165] synonym: "spinal cord metameric segment" EXACT [] synonym: "spinal cord segment" RELATED [TAO:0001332] synonym: "spinal neuromeres" EXACT PLURAL [TAO:0001332] xref: TAO:0001332 xref: ZFA:0001332 is_a: UBERON:0004731 ! neuromere intersection_of: UBERON:0004731 ! neuromere intersection_of: part_of UBERON:0006241 ! future spinal cord relationship: part_of UBERON:0006241 ! future spinal cord [Term] id: UBERON:0014783 name: cloacal muscle namespace: uberon def: "Any muscle organ that is part of a cloaca." [OBOL:automatic] is_a: UBERON:0001630 ! muscle organ is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001630 ! muscle organ intersection_of: part_of UBERON:0000162 ! cloaca relationship: part_of UBERON:0000162 ! cloaca [Term] id: UBERON:0014790 name: lingual septum namespace: uberon def: "The lingual septum consists of a vertical layer of fibrous tissue, extending throughout the entire length of the median plane of the tongue, though not quite reaching the dorsum. It is thicker behind than in front, and occasionally contains a small fibrocartilage, about 6 mm. in length. It is well displayed by making a vertical section across the organ." [Wikipedia:Lingual_septum] synonym: "median fibrous septum" RELATED [Wikipedia:Lingual_septum] synonym: "septum of tongue" EXACT [FMA:54813] synonym: "septum of tongue" RELATED [Wikipedia:Lingual_septum] synonym: "tongue septum" RELATED [Wikipedia:Lingual_septum] xref: EMAPA:18274 xref: FMA:54813 xref: SCTID:368727001 xref: Wikipedia:Lingual_septum is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0003037 ! septum intersection_of: UBERON:0003037 ! septum intersection_of: part_of UBERON:0001723 ! tongue relationship: part_of UBERON:0001723 ! tongue [Term] id: UBERON:0014791 name: musculature of forelimb stylopod namespace: uberon def: "Any collection of muscles that is part of the forelimb stylopod region [Automatically generated definition]." [OBOL:automatic] synonym: "arm musculature" RELATED INCONSISTENT [FMA:50202] synonym: "muscle group of arm" RELATED INCONSISTENT [FMA:50202] synonym: "musculature of arm" RELATED INCONSISTENT [FMA:50202] synonym: "set of muscles of arm" RELATED INCONSISTENT [FMA:50202] xref: FMA:50202 is_a: UBERON:0004474 ! musculature of arm intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0003822 ! forelimb stylopod relationship: part_of UBERON:0003822 ! forelimb stylopod [Term] id: UBERON:0014792 name: musculature of pelvic complex namespace: uberon def: "Any collection of muscles that is part of a pelvic complex. The pelvic complex comprises the pelvic girdle and the associated limb or fin." [OBOL:automatic] synonym: "muscles of lower limb" NARROW [FMA:71297] synonym: "musculature of lower limb" NARROW [FMA:71297] synonym: "musculi membri inferioris" NARROW [FMA:TA] xref: EMAPA:37864 {source="MA:th"} xref: FMA:71297 is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0010709 ! pelvic complex relationship: part_of UBERON:0010709 ! pelvic complex property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0014793 name: musculature of pectoral complex namespace: uberon def: "Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin." [OBOL:automatic] synonym: "muscles of upper limb" NARROW [FMA:71296] synonym: "musculature of upper limb" NARROW [FMA:71296] synonym: "musculi membri superioris" NARROW [FMA:TA] synonym: "set of muscles of upper limb" NARROW [FMA:71296] synonym: "upper limb musculature" NARROW [FMA:71296] xref: EMAPA:37861 {source="MA:th"} xref: FMA:71296 is_a: UBERON:0001015 ! musculature intersection_of: UBERON:0001015 ! musculature intersection_of: part_of UBERON:0010708 ! pectoral complex relationship: part_of UBERON:0010708 ! pectoral complex property_value: editor_note "currently defined by location rather than attachment" xsd:string [Term] id: UBERON:0014794 name: pectoral appendage muscle namespace: uberon def: "Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin)." [OBOL:automatic] is_a: UBERON:0010891 ! pectoral complex muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0004710 ! pectoral appendage relationship: part_of UBERON:0007269 {source="prolog"} ! pectoral appendage musculature [Term] id: UBERON:0014795 name: pelvic appendage muscle namespace: uberon def: "Any muscle organ that is part of a pelvic appendage (hindlimb or pelvic fin)." [OBOL:automatic] is_a: UBERON:0010890 ! pelvic complex muscle intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: part_of UBERON:0004709 ! pelvic appendage relationship: part_of UBERON:0007270 {source="prolog"} ! pelvic appendage musculature [Term] id: UBERON:0014871 name: distal epiphysis of distal phalanx of pedal digit 1 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of pedal digit 1." [OBOL:automatic] synonym: "distal end of distal phalanx of big toe" EXACT [FMA:33036] synonym: "distal epiphysis of distal phalanx of big toe" EXACT [FMA:33036] synonym: "distal epiphysis of distal phalanx of pedal digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "head of distal phalanx of big toe" EXACT [FMA:33036] synonym: "head of distal phalanx of first digit of foot" EXACT [FMA:33036] synonym: "head of distal phalanx of great toe" EXACT [FMA:33036] synonym: "ungual tuberosity of distal phalanx of big toe" RELATED [FMA:33036] xref: FMA:33036 is_a: UBERON:0014876 ! distal epiphysis of distal phalanx of pedal digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004315 ! distal phalanx of pedal digit 1 relationship: part_of UBERON:0004315 ! distal phalanx of pedal digit 1 [Term] id: UBERON:0014872 name: distal epiphysis of distal phalanx of pedal digit 2 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of pedal digit 2." [OBOL:automatic] synonym: "distal end of distal phalanx of second toe" EXACT [FMA:33045] synonym: "distal epiphysis of distal phalanx of pedal digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal epiphysis of distal phalanx of second toe" EXACT [FMA:33045] synonym: "head of distal phalanx of second toe" EXACT [FMA:33045] synonym: "ungual tuberosity of distal phalanx of second toe" RELATED [FMA:33045] xref: FMA:33045 is_a: UBERON:0014876 ! distal epiphysis of distal phalanx of pedal digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004316 ! distal phalanx of pedal digit 2 relationship: part_of UBERON:0004316 ! distal phalanx of pedal digit 2 [Term] id: UBERON:0014873 name: distal epiphysis of distal phalanx of pedal digit 3 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of pedal digit 3." [OBOL:automatic] synonym: "distal end of distal phalanx of third toe" EXACT [FMA:33054] synonym: "distal epiphysis of distal phalanx of pedal digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal epiphysis of distal phalanx of third toe" EXACT [FMA:33054] synonym: "head of distal phalanx of third digit of foot" EXACT [FMA:33054] synonym: "head of distal phalanx of third toe" EXACT [FMA:33054] synonym: "ungual tuberosity of distal phalanx of third toe" RELATED [FMA:33054] xref: FMA:33054 is_a: UBERON:0014876 ! distal epiphysis of distal phalanx of pedal digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004317 ! distal phalanx of pedal digit 3 relationship: part_of UBERON:0004317 ! distal phalanx of pedal digit 3 [Term] id: UBERON:0014874 name: distal epiphysis of distal phalanx of pedal digit 4 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of pedal digit 4." [OBOL:automatic] synonym: "distal end of distal phalanx of fourth toe" EXACT [FMA:33091] synonym: "distal epiphysis of distal phalanx of fourth toe" EXACT [FMA:33091] synonym: "distal epiphysis of distal phalanx of pedal digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "head of distal phalanx of fourth digit of foot" EXACT [FMA:33091] synonym: "head of distal phalanx of fourth toe" EXACT [FMA:33091] synonym: "ungal tuberosity of distal phalanx of fourth toe" RELATED [FMA:33091] xref: FMA:33091 is_a: UBERON:0014876 ! distal epiphysis of distal phalanx of pedal digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004318 ! distal phalanx of pedal digit 4 relationship: part_of UBERON:0004318 ! distal phalanx of pedal digit 4 [Term] id: UBERON:0014875 name: distal epiphysis of distal phalanx of pedal digit 5 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of pedal digit 5." [OBOL:automatic] synonym: "distal end of distal phalanx of little toe" EXACT [FMA:33106] synonym: "distal epiphysis of distal phalanx of little toe" EXACT [FMA:33106] synonym: "distal epiphysis of distal phalanx of pedal digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "head of distal phalanx of fifth digit of foot" EXACT [FMA:33106] synonym: "head of distal phalanx of fifth toe" EXACT [FMA:33106] synonym: "head of distal phalanx of little toe" EXACT [FMA:33106] synonym: "ungual tuberosity of distal phalanx of fifth toe" RELATED [FMA:33106] xref: FMA:33106 is_a: UBERON:0014876 ! distal epiphysis of distal phalanx of pedal digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004319 ! distal phalanx of pedal digit 5 relationship: part_of UBERON:0004319 ! distal phalanx of pedal digit 5 [Term] id: UBERON:0014876 name: distal epiphysis of distal phalanx of pedal digit namespace: uberon synonym: "distal end of distal phalanx of toe" EXACT [] synonym: "head of distal phalanx of digit of foot" EXACT [] synonym: "head of distal phalanx of digit of pes" EXACT [] synonym: "head of distal phalanx of toe" EXACT [] is_a: UBERON:0011976 ! epiphysis of distal phalanx of pes is_a: UBERON:0013122 ! distal epiphysis of phalanx of pes is_a: UBERON:0014887 ! distal epiphysis of distal phalanx of digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0003867 ! distal phalanx of pes [Term] id: UBERON:0014881 name: distal epiphysis of distal phalanx of manual digit 1 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of manual digit 1." [OBOL:automatic] synonym: "distal end of phalanx of right thumb" EXACT [FMA:37609] synonym: "distal epiphysis of distal phalanx of manual digit I" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal epiphysis of distal phalanx of thumb" EXACT [FMA:37609] synonym: "head of distal phalanx of first digit of hand" EXACT [FMA:37609] synonym: "head of distal phalanx of thumb" EXACT [FMA:37609] synonym: "ungual tuberosity of distal phalanx of thumb" RELATED [FMA:37609] xref: FMA:37609 xref: SCTID:182011000 is_a: UBERON:0014886 ! distal epiphysis of distal phalanx of manual digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004337 ! distal phalanx of manual digit 1 relationship: part_of UBERON:0004337 ! distal phalanx of manual digit 1 [Term] id: UBERON:0014882 name: distal epiphysis of distal phalanx of manual digit 2 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of manual digit 2." [OBOL:automatic] synonym: "distal end of distal phalanx of index finger" EXACT [FMA:37621] synonym: "distal end of distal phalanx of second finger" EXACT [FMA:37621] synonym: "distal epiphysis of distal phalanx of index finger" EXACT [FMA:37621] synonym: "distal epiphysis of distal phalanx of manual digit II" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "head of distal phalanx of index finger" EXACT [FMA:37621] synonym: "head of distal phalanx of second finger" EXACT [FMA:37621] synonym: "ungual tuberosity of distal phalanx of index finger" RELATED [FMA:37621] xref: FMA:37621 xref: SCTID:263457005 is_a: UBERON:0014886 ! distal epiphysis of distal phalanx of manual digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004311 ! distal phalanx of manual digit 2 relationship: part_of UBERON:0004311 ! distal phalanx of manual digit 2 [Term] id: UBERON:0014883 name: distal epiphysis of distal phalanx of manual digit 3 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of manual digit 3." [OBOL:automatic] synonym: "distal end of distal phalanx of middle finger" EXACT [FMA:37633] synonym: "distal end of distal phalanx of third finger" EXACT [FMA:37633] synonym: "distal epiphysis of distal phalanx of manual digit III" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal epiphysis of distal phalanx of middle finger" EXACT [FMA:37633] synonym: "head of distal phalanx of middle finger" EXACT [FMA:37633] synonym: "head of distal phalanx of third digit of hand" EXACT [FMA:37633] synonym: "head of distal phalanx of third finger" EXACT [FMA:37633] synonym: "ungual tuberosity of distal phalanx of middle finger" RELATED [FMA:37633] xref: FMA:37633 xref: SCTID:263458000 is_a: UBERON:0014886 ! distal epiphysis of distal phalanx of manual digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004312 ! distal phalanx of manual digit 3 relationship: part_of UBERON:0004312 ! distal phalanx of manual digit 3 [Term] id: UBERON:0014884 name: distal epiphysis of distal phalanx of manual digit 4 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of manual digit 4." [OBOL:automatic] synonym: "distal end of distal phalanx of fourth finger" EXACT [FMA:37645] synonym: "distal end of distal phalanx of ring finger" EXACT [FMA:37645] synonym: "distal epiphysis of distal phalanx of manual digit IV" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "distal epiphysis of distal phalanx of ring finger" EXACT [FMA:37645] synonym: "head of distal phalanx of fourth digit of hand" EXACT [FMA:37645] synonym: "head of distal phalanx of fourth finger" EXACT [FMA:37645] synonym: "head of distal phalanx of ring finger" EXACT [FMA:37645] synonym: "ungual tuberosity of distal phalanx of ring finger" RELATED [FMA:37645] xref: FMA:37645 xref: SCTID:263459008 is_a: UBERON:0014886 ! distal epiphysis of distal phalanx of manual digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004313 ! distal phalanx of manual digit 4 relationship: part_of UBERON:0004313 ! distal phalanx of manual digit 4 [Term] id: UBERON:0014885 name: distal epiphysis of distal phalanx of manual digit 5 namespace: uberon def: "A distal epiphysis that is part of a distal phalanx of manual digit 5." [OBOL:automatic] synonym: "distal end of distal phalanx of fifth finger" EXACT [FMA:37657] synonym: "distal end of distal phalanx of little finger" EXACT [FMA:37657] synonym: "distal epiphysis of distal phalanx of little finger" EXACT [FMA:37657] synonym: "distal epiphysis of distal phalanx of manual digit V" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] synonym: "head of distal phalanx of fifth digit of hand" EXACT [FMA:37657] synonym: "head of distal phalanx of fifth finger" EXACT [FMA:37657] synonym: "head of distal phalanx of little finger" EXACT [FMA:37657] synonym: "ungual tuberosity of distal phalanx of little finger" RELATED [FMA:37657] xref: FMA:37657 xref: SCTID:263460003 is_a: UBERON:0014886 ! distal epiphysis of distal phalanx of manual digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004314 ! distal phalanx of manual digit 5 relationship: part_of UBERON:0004314 ! distal phalanx of manual digit 5 [Term] id: UBERON:0014886 name: distal epiphysis of distal phalanx of manual digit namespace: uberon synonym: "distal end of distal phalanx of finger" EXACT [] synonym: "head of distal phalanx of digit of hand" EXACT [] synonym: "head of distal phalanx of digit of manus" EXACT [] synonym: "head of distal phalanx of finger" EXACT [] xref: SCTID:182006002 is_a: UBERON:0004409 ! distal epiphysis of phalanx of manus is_a: UBERON:0011979 ! epiphysis of distal phalanx of manus is_a: UBERON:0014887 ! distal epiphysis of distal phalanx of digit intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0003865 ! distal phalanx of manus [Term] id: UBERON:0014887 name: distal epiphysis of distal phalanx of digit namespace: uberon def: "A distal epiphysis that is part of a distal phalanx." [OBOL:automatic] synonym: "distal end of distal phalanx of digit" EXACT [] synonym: "head of distal phalanx" EXACT [] synonym: "head of distal phalanx of digit" EXACT [] synonym: "head of distal phalanx of digit of autopod" EXACT [] is_a: UBERON:0004448 ! distal epiphysis of phalanx intersection_of: UBERON:0004379 ! distal epiphysis intersection_of: part_of UBERON:0004300 ! distal phalanx relationship: part_of UBERON:0004300 ! distal phalanx [Term] id: UBERON:0014891 name: brainstem white matter namespace: uberon def: "White matter that is part of a brainstem [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim synonym: "brain stem white matter" RELATED [EMAPA:35189] synonym: "brainstem tract/commissure" RELATED [] synonym: "brainstem tracts" RELATED [] synonym: "brainstem tracts and commissures" RELATED [] xref: EMAPA:35189 xref: FMA:282112 xref: MA:0002741 xref: SCTID:360442003 is_a: UBERON:0003544 ! brain white matter intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0002298 ! brainstem relationship: part_of UBERON:0002298 ! brainstem [Term] id: UBERON:0014892 name: skeletal muscle organ namespace: uberon def: "A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles)." [GOC:dos] synonym: "skeletal muscle" BROAD [] xref: AAO:0011099 xref: BTO:0001103 xref: CALOHA:TS-0933 xref: EFO:0000888 xref: EHDAA:5035 xref: EHDAA:5043 xref: EHDAA:5978 xref: EHDAA:5984 xref: EMAPA:35988 xref: EV:0100377 xref: GAID:141 xref: MA:0003148 xref: MAT:0000302 xref: MESH:D018482 xref: MIAA:0000302 xref: TAO:0005277 xref: VHOG:0000319 xref: XAO:0000174 xref: ZFA:0005277 is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue intersection_of: develops_from UBERON:0003082 ! myotome intersection_of: surrounded_by UBERON:0011899 ! epimysium intersection_of: synapsed_by CL:0000100 ! motor neuron relationship: composed_primarily_of UBERON:0001134 ! skeletal muscle tissue relationship: develops_from UBERON:0003082 ! myotome relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0018254 ! skeletal musculature relationship: surrounded_by UBERON:0011899 ! epimysium relationship: synapsed_by CL:0000100 ! motor neuron [Term] id: UBERON:0014903 name: primordial vasculature namespace: uberon def: "A portion of tissue that will develop into vasculature." [ZFA:0005076, ZFA:curator] xref: EFO:0003708 xref: TAO:0005076 xref: ZFA:0005076 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0001048 ! primordium intersection_of: UBERON:0001048 ! primordium intersection_of: has_potential_to_develop_into UBERON:0002049 ! vasculature relationship: has_potential_to_develop_into UBERON:0002049 ! vasculature relationship: part_of UBERON:0011695 ! embryonic cardiovascular system [Term] id: UBERON:0014907 name: intersomitic vessel namespace: uberon def: "One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites." [MGI:anna] subset: pheno_slim synonym: "intersegmental vessel" EXACT [ZFA:0001285] synonym: "intersegmental vessels" EXACT PLURAL [ZFA:0001285] synonym: "intersomitic blood vessel" EXACT [XAO:0004075] synonym: "intersomitic vessels" EXACT PLURAL [ZFA:0001285] synonym: "segmental vessel" EXACT [ZFA:0001285] xref: EFO:0003664 xref: EMAPA:37389 {source="MA:th"} xref: TAO:0001285 xref: XAO:0004075 xref: ZFA:0001285 is_a: UBERON:0001981 {source="ZFA"} ! blood vessel relationship: develops_from UBERON:0005805 {source="ZFA"} ! dorsal aorta property_value: UBPROP:0000001 "Blood vessels that connect the dorsal aorta or the posterior cardinal vein and the dorsal longitudinal anastomotic vessel. They run along the vertical myotomal boundaries. At early stages these don't have venous or arterial markers[ZFA:0001285, ZFIN:ZDB-PUB-030908-4]." xsd:string {source="ZFA:0001285, ZFIN:ZDB-PUB-030908-4"} [Term] id: UBERON:0014950 name: layer of developing cerebral cortex namespace: uberon is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005423 ! developing anatomical structure relationship: part_of UBERON:0000956 {source="EMAPA"} ! cerebral cortex property_value: IAO:0000232 "these layers primarily refer to the mammalian future neocortex" xsd:string [Term] id: UBERON:0015001 name: radius endochondral element namespace: uberon def: "The major preaxial endrochondral skeletal element in the anterior zeugopod." [https://github.com/obophenotype/uberon/issues/70, UBERON:mah] synonym: "radius element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "radius skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015021 ! forelimb endochondral element union_of: UBERON:0001423 ! radius bone union_of: UBERON:0006286 ! radius cartilage element union_of: UBERON:0010846 ! radius pre-cartilage condensation relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton [Term] id: UBERON:0015002 name: radius-ulna endochondral element namespace: uberon def: "A radius-ulna bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "radius-ulna element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "radius-ulna skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015021 ! forelimb endochondral element union_of: UBERON:0006287 ! radius-ulna pre-cartilage condensation union_of: UBERON:0006715 ! radio-ulna union_of: UBERON:0010848 ! radius-ulna cartilage element relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton [Term] id: UBERON:0015003 name: ulna endochondral element namespace: uberon def: "Major postaxial endrochondral skeletal element in the anterior zeugopod." [https://github.com/obophenotype/uberon/issues/70, UBERON:mah] comment: The corresponding element in the posterior fin/limb is the fibula. synonym: "ulna element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "ulna skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015021 ! forelimb endochondral element union_of: UBERON:0001424 ! ulna union_of: UBERON:0006306 ! ulna cartilage element union_of: UBERON:0010847 ! ulna pre-cartilage condensation relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0010703 ! forelimb zeugopod skeleton [Term] id: UBERON:0015004 name: tibia endochondral element namespace: uberon def: "The major preaxial endochondral element in the posterior zeugopod[Phenoscape]." [https://github.com/obophenotype/uberon/issues/71, PHENOSCAPE:mah] synonym: "tibia element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "tibia skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015022 ! hindlimb endochondral element union_of: UBERON:0000979 ! tibia union_of: UBERON:0010849 ! tibia cartilage element union_of: UBERON:0010850 ! tibia pre-cartilage condensation relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0010720 ! hindlimb zeugopod skeleton [Term] id: UBERON:0015007 name: cervical vertebra endochondral element namespace: uberon def: "A vertebral endochondral element in the cervical region of the vertebral column." [http://orcid.org/0000-0002-6601-2165] synonym: "cervical vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "cervical vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: part_of UBERON:0006072 ! cervical region of vertebral column union_of: UBERON:0002413 ! cervical vertebra union_of: UBERON:0013505 ! cervical vertebra cartilage element union_of: UBERON:0013506 ! cervical vertebra pre-cartilage condensation relationship: part_of UBERON:0006072 ! cervical region of vertebral column [Term] id: UBERON:0015008 name: thoracic vertebra endochondral element namespace: uberon def: "A vertebral endochondral element in the thoracic region of the vertebral column." [http://orcid.org/0000-0002-6601-2165] synonym: "thoracic vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "thoracic vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: part_of UBERON:0006073 ! thoracic region of vertebral column union_of: UBERON:0002347 ! thoracic vertebra union_of: UBERON:0013507 ! thoracic vertebra cartilage element union_of: UBERON:0013508 ! thoracic vertebra pre-cartilage condensation relationship: part_of UBERON:0006073 ! thoracic region of vertebral column [Term] id: UBERON:0015009 name: lumbar vertebra endochondral element namespace: uberon def: "A lumbar vertebra bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "lumbar vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "lumbar vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0005173 ! abdominal segment element is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: part_of UBERON:0006074 ! lumbar region of vertebral column union_of: UBERON:0002414 ! lumbar vertebra union_of: UBERON:0013509 ! lumbar vertebra cartilage element union_of: UBERON:0013510 ! lumbar vertebra pre-cartilage condensation relationship: part_of UBERON:0006074 ! lumbar region of vertebral column [Term] id: UBERON:0015010 name: sacral vertebra endochondral element namespace: uberon def: "A vertebra endochondral element that is part of the sacral region of the vertebral column." [http://orcid.org/0000-0002-6601-2165] synonym: "sacral vertebra element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "sacral vertebra skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: part_of UBERON:0006075 ! sacral region of vertebral column union_of: UBERON:0001094 ! sacral vertebra union_of: UBERON:0010744 ! sacral vertebra pre-cartilage condensation union_of: UBERON:0010745 ! sacral vertebra cartilage element relationship: part_of UBERON:0006075 ! sacral region of vertebral column [Term] id: UBERON:0015013 name: fibula endochondral element namespace: uberon def: "The major postaxial endochondral element in the posterior zeugopod[Phenoscape]." [https://github.com/obophenotype/uberon/issues/73, PHENOSCAPE:mah] synonym: "fibula element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "fibula skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015022 ! hindlimb endochondral element union_of: UBERON:0001446 ! fibula union_of: UBERON:0010851 ! fibula cartilage element union_of: UBERON:0010852 ! fibula pre-cartilage condensation relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/mellybelly relationship: part_of UBERON:0010720 ! hindlimb zeugopod skeleton [Term] id: UBERON:0015014 name: calcaneum endochondral element namespace: uberon def: "A calcaneum bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "calcaneum element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "calcaneum skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015050 ! tarsus endochondral element union_of: UBERON:0001450 ! calcaneus union_of: UBERON:0010801 ! calcaneum pre-cartilage condensation union_of: UBERON:0010842 ! calcaneum cartilage element [Term] id: UBERON:0015015 name: supraoccipital endochondral element namespace: uberon def: "A supraoccipital bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "supraoccipital element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "supraoccipital skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010363 ! endochondral element union_of: UBERON:0004747 ! supraoccipital bone union_of: UBERON:0011162 ! supraoccipital cartilage element union_of: UBERON:0011163 ! supraoccipital pre-cartilage condensation relationship: part_of UBERON:0001703 ! neurocranium relationship: part_of UBERON:0002241 ! chondrocranium relationship: part_of UBERON:0005902 ! occipital region [Term] id: UBERON:0015019 name: rib endochondral element namespace: uberon def: "A rib bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "rib element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "rib skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0010363 ! endochondral element union_of: UBERON:0002228 ! rib union_of: UBERON:0006288 ! rib cartilage element union_of: UBERON:0006289 ! rib pre-cartilage condensation relationship: part_of UBERON:0014478 ! rib skeletal system property_value: UBPROP:0000008 "Humans have 24 ribs (12 pairs). The first seven sets of ribs, known as 'true ribs', are directly attached to the sternum through the costal cartilage. The following five sets are known as 'false ribs', three of these sharing a common cartilaginous connection to the sternum, while the last two (eleventh and twelfth ribs) are termed floating ribs (costae fluitantes) or vertebral ribs. They are attached to the vertebrae only, and not to the sternum or cartilage coming off of the sternum. Some people are missing one of the two pairs of floating ribs, while others have a third pair. Rib removal is the surgical excision of ribs for therapeutic or cosmetic reasons. In fish, there are often two sets of ribs attached to the vertebral column. One set, the dorsal ribs, are found in the dividing septum between the upper and lower parts of the main muscle segments, projecting roughly sideways from the vertebral column. The second set, of ventral ribs arise from the vertebral column just below the dorsal ribs, and enclose the lower body, often joining at the tips. Not all species possess both types of rib, with the dorsal ribs being most commonly absent. Sharks, for example, have no dorsal ribs, and only very short ventral ribs, while lampreys have no ribs at all. In some teleosts, there may be additional rib-like bones within the muscle mass. Tetrapods, however, only ever have a single set of ribs which are probably homologous with the dorsal ribs of fishes. In the early tetrapods, every vertebra bore a pair of ribs, although those on the thoracic vertebrae are typically the longest. The sacral ribs were stout and short, since they formed part of the pelvis, connecting the backbone to the hip bones.[1] In most subsequent forms, many of these early ribs have been lost, and in living amphibians and reptiles, there is great variation in rib structure and number. For example, turtles have only eight pairs of ribs, which are developed into a bony or cartilagenous carapace and plastron, while snakes have numerous ribs running along the full length of their trunk. Frogs typically have no ribs, aside from a sacral pair, which form part of the pelvis.[1]. In birds, ribs are present as distinct bones only on the thoracic region, although small fused ribs are present on the cervical vertebrae. The thoracic ribs of birds possess a wide projection to the rear; this uncinate process is an attachment for the shoulder muscles.[1]. Mammals usually also only have distinct ribs on the thoracic vertebra, although fixed cervical ribs are also present in monotremes. In marsupials and placental mammals, the cervical and lumbar ribs are found only as tiny remnants fused to the vertebrae, where they are referred to as transverse processes. In general, the structure and number of the true ribs in humans is similar to that in other mammals. Unlike reptiles, caudal ribs are never found in mammals." xsd:string [Term] id: UBERON:0015021 name: forelimb endochondral element namespace: uberon def: "A forelimb bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "forelimb skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015061 ! limb endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0002102 ! forelimb union_of: UBERON:0008962 ! forelimb bone union_of: UBERON:0010883 ! forelimb cartilage element union_of: UBERON:0010884 ! forelimb bone pre-cartilage condensation relationship: part_of UBERON:0001440 ! forelimb skeleton [Term] id: UBERON:0015022 name: hindlimb endochondral element namespace: uberon def: "A hindlimb bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "hindlimb bone skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015061 ! limb endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0002103 ! hindlimb union_of: UBERON:0003464 ! hindlimb bone union_of: UBERON:0010885 ! hindlimb cartilage element union_of: UBERON:0010886 ! hindlimb pre-cartilage condensation relationship: part_of UBERON:0001441 ! hindlimb skeleton [Term] id: UBERON:0015023 name: phalanx endochondral element namespace: uberon def: "A phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015063 ! autopod endochondral element union_of: UBERON:0003221 ! phalanx union_of: UBERON:0010700 ! phalanx pre-cartilage condensation union_of: UBERON:0010701 ! phalanx cartilage element relationship: part_of UBERON:0002544 ! digit relationship: part_of UBERON:0012150 ! skeleton of digitopodium [Term] id: UBERON:0015024 name: manual digit phalanx endochondral element namespace: uberon def: "A manual digit phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015021 ! forelimb endochondral element is_a: UBERON:0015023 ! phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0002389 ! manual digit union_of: UBERON:0001436 ! phalanx of manus union_of: UBERON:0010586 ! manual digit phalanx pre-cartilage condensation union_of: UBERON:0010686 ! manual digit phalanx cartilage element relationship: part_of UBERON:0002389 ! manual digit relationship: part_of UBERON:0010688 ! skeleton of manual acropodium relationship: part_of UBERON:5102389 ! manual digit digitopodial skeleton [Term] id: UBERON:0015025 name: manual digit 1 phalanx endochondral element namespace: uberon def: "A manual digit 1 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 1 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 1 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit I phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0001463 ! manual digit 1 union_of: UBERON:0003620 ! manual digit 1 phalanx union_of: UBERON:0010575 ! manual digit 1 phalanx pre-cartilage condensation union_of: UBERON:0010675 ! manual digit 1 phalanx cartilage element relationship: part_of UBERON:0001463 ! manual digit 1 relationship: part_of UBERON:5101463 ! manual digit 1 digitopodial skeleton [Term] id: UBERON:0015026 name: manual digit 2 phalanx endochondral element namespace: uberon def: "A manual digit 2 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 2 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 2 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit II phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003622 ! manual digit 2 union_of: UBERON:0003636 ! manual digit 2 phalanx union_of: UBERON:0010576 ! manual digit 2 phalanx pre-cartilage condensation union_of: UBERON:0010676 ! manual digit 2 phalanx cartilage element relationship: part_of UBERON:0003622 ! manual digit 2 relationship: part_of UBERON:5103622 ! manual digit 2 digitopodial skeleton [Term] id: UBERON:0015027 name: manual digit 3 phalanx endochondral element namespace: uberon def: "A manual digit 3 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 3 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 3 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit III phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003623 ! manual digit 3 union_of: UBERON:0003637 ! manual digit 3 phalanx union_of: UBERON:0010577 ! manual digit 3 phalanx pre-cartilage condensation union_of: UBERON:0010677 ! manual digit 3 phalanx cartilage element relationship: part_of UBERON:0003623 ! manual digit 3 relationship: part_of UBERON:5103623 ! manual digit 3 digitopodial skeleton [Term] id: UBERON:0015028 name: manual digit 4 phalanx endochondral element namespace: uberon def: "A manual digit 4 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 4 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 4 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit IV phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003624 ! manual digit 4 union_of: UBERON:0003638 ! manual digit 4 phalanx union_of: UBERON:0010578 ! manual digit 4 phalanx pre-cartilage condensation union_of: UBERON:0010678 ! manual digit 4 phalanx cartilage element relationship: part_of UBERON:0003624 ! manual digit 4 relationship: part_of UBERON:5103624 ! manual digit 4 digitopodial skeleton [Term] id: UBERON:0015029 name: manual digit 5 phalanx endochondral element namespace: uberon def: "A manual digit 5 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 5 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 5 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit V phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015024 ! manual digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003625 ! manual digit 5 union_of: UBERON:0003639 ! manual digit 5 phalanx union_of: UBERON:0010579 ! manual digit 5 phalanx pre-cartilage condensation union_of: UBERON:0010679 ! manual digit 5 phalanx cartilage element relationship: part_of UBERON:0003625 ! manual digit 5 relationship: part_of UBERON:5103625 ! manual digit 5 digitopodial skeleton [Term] id: UBERON:0015030 name: pedal digit phalanx endochondral element namespace: uberon def: "A pedal digit phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015022 ! hindlimb endochondral element is_a: UBERON:0015023 ! phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0001466 ! pedal digit union_of: UBERON:0001449 ! phalanx of pes union_of: UBERON:0010585 ! pedal digit phalanx pre-cartilage condensation union_of: UBERON:0010685 ! pedal digit phalanx cartilage element relationship: part_of UBERON:0001466 ! pedal digit relationship: part_of UBERON:0010696 ! skeleton of pedal acropodium relationship: part_of UBERON:5101466 ! pedal digit digitopodial skeleton [Term] id: UBERON:0015031 name: pedal digit 1 phalanx endochondral element namespace: uberon def: "A pedal digit 1 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 1 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 1 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit I phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003631 ! pedal digit 1 union_of: UBERON:0003640 ! pedal digit 1 phalanx union_of: UBERON:0010580 ! pedal digit 1 phalanx pre-cartilage condensation union_of: UBERON:0010680 ! pedal digit 1 phalanx cartilage element relationship: part_of UBERON:0003631 ! pedal digit 1 relationship: part_of UBERON:5103631 ! pedal digit 1 digitopodial skeleton [Term] id: UBERON:0015032 name: pedal digit 2 phalanx endochondral element namespace: uberon def: "A pedal digit 2 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 2 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 2 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit II phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003632 ! pedal digit 2 union_of: UBERON:0003641 ! pedal digit 2 phalanx union_of: UBERON:0010581 ! pedal digit 2 phalanx pre-cartilage condensation union_of: UBERON:0010681 ! pedal digit 2 phalanx cartilage element relationship: part_of UBERON:0003632 ! pedal digit 2 relationship: part_of UBERON:5103632 ! pedal digit 2 digitopodial skeleton [Term] id: UBERON:0015033 name: pedal digit 3 phalanx endochondral element namespace: uberon def: "A pedal digit 3 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 3 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 3 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit III phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003633 ! pedal digit 3 union_of: UBERON:0003642 ! pedal digit 3 phalanx union_of: UBERON:0010582 ! pedal digit 3 phalanx pre-cartilage condensation union_of: UBERON:0010682 ! pedal digit 3 phalanx cartilage element relationship: part_of UBERON:0003633 ! pedal digit 3 relationship: part_of UBERON:5103633 ! pedal digit 3 digitopodial skeleton [Term] id: UBERON:0015034 name: pedal digit 4 phalanx endochondral element namespace: uberon def: "A pedal digit 4 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 4 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 4 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit IV phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003634 ! pedal digit 4 union_of: UBERON:0003862 ! pedal digit 4 phalanx union_of: UBERON:0010583 ! pedal digit 4 phalanx pre-cartilage condensation union_of: UBERON:0010683 ! pedal digit 4 phalanx cartilage element relationship: part_of UBERON:0003634 ! pedal digit 4 relationship: part_of UBERON:5103634 ! pedal digit 4 digitopodial skeleton [Term] id: UBERON:0015035 name: pedal digit 5 phalanx endochondral element namespace: uberon def: "A pedal digit 5 phalanx bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 5 phalanx element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 5 phalanx skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit V phalanx endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015030 ! pedal digit phalanx endochondral element intersection_of: UBERON:0015023 ! phalanx endochondral element intersection_of: part_of UBERON:0003635 ! pedal digit 5 union_of: UBERON:0003863 ! pedal digit 5 phalanx union_of: UBERON:0010584 ! pedal digit 5 phalanx pre-cartilage condensation union_of: UBERON:0010684 ! pedal digit 5 phalanx cartilage element relationship: part_of UBERON:0003635 ! pedal digit 5 relationship: part_of UBERON:5103635 ! pedal digit 5 digitopodial skeleton [Term] id: UBERON:0015036 name: pedal digit metatarsal endochondral element namespace: uberon def: "A pedal digit metatarsal bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit metatarsal element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit metatarsal skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015022 ! hindlimb endochondral element is_a: UBERON:0015063 ! autopod endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0000983 ! metatarsus region union_of: UBERON:0010545 ! metatarsus skeleton union_of: UBERON:0010687 ! pedal digit metatarsal pre-cartilage condensation union_of: UBERON:0010697 ! pedal digit metatarsal cartilage element relationship: part_of UBERON:0000983 ! metatarsus region relationship: part_of UBERON:0012152 ! skeleton of pedal digitopodium [Term] id: UBERON:0015037 name: pedal digit 1 metatarsal endochondral element namespace: uberon def: "A pedal digit 1 metatarsal bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 1 metatarsal element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 1 metatarsal skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit I metatarsal endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: part_of UBERON:5103631 ! pedal digit 1 digitopodial skeleton union_of: UBERON:0003650 ! metatarsal bone of digit 1 union_of: UBERON:0010547 ! pedal digit 1 metatarsal pre-cartilage condensation union_of: UBERON:0010557 ! pedal digit 1 metatarsal cartilage element relationship: part_of UBERON:5103631 ! pedal digit 1 digitopodial skeleton [Term] id: UBERON:0015038 name: pedal digit 2 metatarsal endochondral element namespace: uberon def: "A pedal digit 2 metatarsal bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 2 metatarsal element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 2 metatarsal skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit II metatarsal endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: part_of UBERON:5103632 ! pedal digit 2 digitopodial skeleton union_of: UBERON:0003651 ! metatarsal bone of digit 2 union_of: UBERON:0010548 ! pedal digit 2 metatarsal pre-cartilage condensation union_of: UBERON:0010558 ! pedal digit 2 metatarsal cartilage element relationship: part_of UBERON:5103632 ! pedal digit 2 digitopodial skeleton [Term] id: UBERON:0015039 name: pedal digit 3 metatarsal endochondral element namespace: uberon def: "A pedal digit 3 metatarsal bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 3 metatarsal element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 3 metatarsal skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit III metatarsal endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: part_of UBERON:5103633 ! pedal digit 3 digitopodial skeleton union_of: UBERON:0003652 ! metatarsal bone of digit 3 union_of: UBERON:0010549 ! pedal digit 3 metatarsal pre-cartilage condensation union_of: UBERON:0010559 ! pedal digit 3 metatarsal cartilage element relationship: part_of UBERON:5103633 ! pedal digit 3 digitopodial skeleton [Term] id: UBERON:0015040 name: pedal digit 4 metatarsal endochondral element namespace: uberon def: "A pedal digit 4 metatarsal bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 4 metatarsal element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 4 metatarsal skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit IV metatarsal endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: part_of UBERON:5103634 ! pedal digit 4 digitopodial skeleton union_of: UBERON:0003653 ! metatarsal bone of digit 4 union_of: UBERON:0010550 ! pedal digit 4 metatarsal pre-cartilage condensation union_of: UBERON:0010560 ! pedal digit 4 metatarsal cartilage element relationship: part_of UBERON:5103634 ! pedal digit 4 digitopodial skeleton [Term] id: UBERON:0015041 name: pedal digit 5 metatarsal endochondral element namespace: uberon def: "A pedal digit 5 metatarsal bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 5 metatarsal element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit 5 metatarsal skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pedal digit V metatarsal endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: UBERON:0015036 ! pedal digit metatarsal endochondral element intersection_of: part_of UBERON:5103635 ! pedal digit 5 digitopodial skeleton union_of: UBERON:0003654 ! metatarsal bone of digit 5 union_of: UBERON:0010551 ! pedal digit 5 metatarsal pre-cartilage condensation union_of: UBERON:0010561 ! pedal digit 5 metatarsal cartilage element relationship: part_of UBERON:5103635 ! pedal digit 5 digitopodial skeleton [Term] id: UBERON:0015042 name: manual digit metacarpus endochondral element namespace: uberon def: "A manual digit metacarpus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit metacarpus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit metacarpus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015021 ! forelimb endochondral element is_a: UBERON:0015063 ! autopod endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0004453 ! metacarpus region union_of: UBERON:0010544 ! metacarpus skeleton union_of: UBERON:0010698 ! manual digit metacarpus pre-cartilage condensation union_of: UBERON:0010699 ! manual digit metacarpus cartilage element relationship: part_of UBERON:0004453 ! metacarpus region relationship: part_of UBERON:0012151 ! skeleton of manual digitopodium [Term] id: UBERON:0015043 name: manual digit 1 metacarpus endochondral element namespace: uberon def: "A manual digit 1 metacarpus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 1 metacarpus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 1 metacarpus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit I metacarpus endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: part_of UBERON:5101463 ! manual digit 1 digitopodial skeleton union_of: UBERON:0003645 ! metacarpal bone of digit 1 union_of: UBERON:0010565 ! manual digit 1 metacarpus pre-cartilage condensation union_of: UBERON:0010570 ! manual digit 1 metacarpus cartilage element relationship: part_of UBERON:5101463 ! manual digit 1 digitopodial skeleton [Term] id: UBERON:0015044 name: manual digit 2 metacarpus endochondral element namespace: uberon def: "A manual digit 2 metacarpus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 2 metacarpus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 2 metacarpus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit II metacarpus endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: part_of UBERON:5103622 ! manual digit 2 digitopodial skeleton union_of: UBERON:0003646 ! metacarpal bone of digit 2 union_of: UBERON:0010566 ! manual digit 2 metacarpus pre-cartilage condensation union_of: UBERON:0010571 ! manual digit 2 metacarpus cartilage element relationship: part_of UBERON:5103622 ! manual digit 2 digitopodial skeleton [Term] id: UBERON:0015045 name: manual digit 3 metacarpus endochondral element namespace: uberon def: "A manual digit 3 metacarpus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 3 metacarpus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 3 metacarpus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit III metacarpus endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: part_of UBERON:5103623 ! manual digit 3 digitopodial skeleton union_of: UBERON:0003647 ! metacarpal bone of digit 3 union_of: UBERON:0010567 ! manual digit 3 metacarpus pre-cartilage condensation union_of: UBERON:0010572 ! manual digit 3 metacarpus cartilage element relationship: part_of UBERON:5103623 ! manual digit 3 digitopodial skeleton [Term] id: UBERON:0015046 name: manual digit 4 metacarpus endochondral element namespace: uberon def: "A manual digit 4 metacarpus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 4 metacarpus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 4 metacarpus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit IV metacarpus endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: part_of UBERON:5103624 ! manual digit 4 digitopodial skeleton union_of: UBERON:0003648 ! metacarpal bone of digit 4 union_of: UBERON:0010568 ! manual digit 4 metacarpus pre-cartilage condensation union_of: UBERON:0010573 ! manual digit 4 metacarpus cartilage element relationship: part_of UBERON:5103624 ! manual digit 4 digitopodial skeleton [Term] id: UBERON:0015047 name: manual digit 5 metacarpus endochondral element namespace: uberon def: "A manual digit 5 metacarpus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 5 metacarpus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit 5 metacarpus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "manual digit V metacarpus endochondral element" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: UBERON:0015042 ! manual digit metacarpus endochondral element intersection_of: part_of UBERON:5103625 ! manual digit 5 digitopodial skeleton union_of: UBERON:0003649 ! metacarpal bone of digit 5 union_of: UBERON:0010569 ! manual digit 5 metacarpus pre-cartilage condensation union_of: UBERON:0010574 ! manual digit 5 metacarpus cartilage element relationship: part_of UBERON:5103625 ! manual digit 5 digitopodial skeleton [Term] id: UBERON:0015049 name: carpus endochondral element namespace: uberon def: "A carpus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "carpus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "carpus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015021 ! forelimb endochondral element is_a: UBERON:0015063 ! autopod endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0004452 ! carpal region union_of: UBERON:0001435 ! carpal bone union_of: UBERON:0006213 ! carpus cartilage element union_of: UBERON:0006214 ! carpus pre-cartilage condensation relationship: part_of UBERON:0009880 ! carpal skeleton [Term] id: UBERON:0015050 name: tarsus endochondral element namespace: uberon def: "A tarsus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "tarsus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "tarsus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015022 ! hindlimb endochondral element is_a: UBERON:0015063 ! autopod endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0004454 ! tarsal region union_of: UBERON:0001447 ! tarsal bone union_of: UBERON:0010540 ! tarsus pre-cartilage condensation union_of: UBERON:0010541 ! tarsus cartilage element relationship: part_of UBERON:0009879 ! tarsal skeleton [Term] id: UBERON:0015052 name: femur endochondral element namespace: uberon def: "A femur bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "femur element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "femur skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015022 ! hindlimb endochondral element union_of: UBERON:0000981 ! femur union_of: UBERON:0006234 ! femur pre-cartilage condensation union_of: UBERON:0010129 ! femur cartilage element relationship: part_of UBERON:0000376 ! hindlimb stylopod [Term] id: UBERON:0015053 name: humerus endochondral element namespace: uberon def: "A humerus bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "humerus element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "humerus skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0015021 ! forelimb endochondral element union_of: UBERON:0000976 ! humerus union_of: UBERON:0006245 ! humerus cartilage element union_of: UBERON:0006246 ! humerus pre-cartilage condensation relationship: part_of UBERON:0003822 ! forelimb stylopod [Term] id: UBERON:0015054 name: iliac endochondral element namespace: uberon def: "An iliac bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "iliac element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "iliac skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0010363 ! endochondral element union_of: UBERON:0001273 ! ilium union_of: UBERON:0006247 ! iliac pre-cartilage condensation union_of: UBERON:0010714 ! iliac cartilage element relationship: part_of UBERON:0007832 ! pelvic girdle skeleton [Term] id: UBERON:0015055 name: pubic endochondral element namespace: uberon def: "A pubic bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pubic element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "pubic skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0010363 ! endochondral element union_of: UBERON:0001275 ! pubis union_of: UBERON:0006285 ! pubic pre-cartilage condensation union_of: UBERON:0010718 ! pubic cartilage element relationship: part_of UBERON:0007832 ! pelvic girdle skeleton [Term] id: UBERON:0015056 name: ischial endochondral element namespace: uberon def: "An ischial bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "ischial element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "ischial skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0010363 ! endochondral element union_of: UBERON:0001274 ! ischium union_of: UBERON:0006254 ! ischial cartilage element union_of: UBERON:0006255 ! ischial pre-cartilage condensation relationship: part_of UBERON:0007832 ! pelvic girdle skeleton [Term] id: UBERON:0015057 name: scapula endochondral element namespace: uberon def: "A scapula bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "scapula element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "scapula skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0010363 ! endochondral element union_of: UBERON:0006290 ! scapula cartilage element union_of: UBERON:0006291 ! scapula pre-cartilage condensation union_of: UBERON:0006849 ! scapula relationship: part_of UBERON:0007831 ! pectoral girdle skeleton [Term] id: UBERON:0015060 name: sphenoid endochondral element namespace: uberon def: "A sphenoid bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "sphenoid bone skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "sphenoid element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010363 ! endochondral element union_of: UBERON:0001677 ! sphenoid bone union_of: UBERON:0009191 ! sphenoid bone pre-cartilage condensation union_of: UBERON:0009193 ! sphenoid cartilage element relationship: part_of UBERON:0011156 ! facial skeleton [Term] id: UBERON:0015061 name: limb endochondral element namespace: uberon def: "A limb bone or its cartilage or pre-cartilage precursor." [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "limb bone endochondral element" EXACT [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] synonym: "limb bone skeletal element" BROAD [https://github.com/obophenotype/uberon/wiki/Modeling-endochondral-elements-Design-Pattern] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010363 ! endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0002101 ! limb union_of: UBERON:0002428 ! limb bone union_of: UBERON:0010881 ! limb cartilage element union_of: UBERON:0010882 ! limb bone pre-cartilage condensation relationship: part_of UBERON:0004381 ! skeleton of limb [Term] id: UBERON:0015063 name: autopod endochondral element namespace: uberon def: "An endochondral element that is part of a autopod region." [OBOL:automatic] is_a: UBERON:0015061 ! limb endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: part_of UBERON:0002470 ! autopod region relationship: part_of UBERON:0006717 {source="cjm"} ! autopodial skeleton property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern [Term] id: UBERON:0015064 name: autopod cartilage namespace: uberon def: "An autopod endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0010881 ! limb cartilage element is_a: UBERON:0015063 ! autopod endochondral element intersection_of: UBERON:0015063 ! autopod endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue property_value: UBPROP:0000006 https://github.com/obophenotype/uberon/wiki/Skeleton-partonomy-Design-Pattern [Term] id: UBERON:0015067 name: centrale endochondral element namespace: uberon def: "Endochondral element located between the proximal and distal rows of carpals or tarsals and thus representing the central carpals or tarsals[PHENOSCAPE]." [PHENOSCAPE:AMAO] synonym: "central mesopodium element" EXACT [UBERON:0012131] synonym: "centralia" RELATED PLURAL [UBERON:0012131] is_a: UBERON:0015063 ! autopod endochondral element relationship: part_of UBERON:0009878 ! mesopodial skeleton property_value: IAO:0000232 "This term corresponds both to the navicular bone in the pes and the similar central carpals in the manus" xsd:string property_value: UBPROP:0000012 "the FMA term is under 'general anatomical term'." xsd:string {external_ontology="FMA"} [Term] id: UBERON:0015068 name: distal carpal endochondral element namespace: uberon def: "A distal mesopodial endochondral element that is part of a forelimb." [OBOL:automatic] synonym: "distal carpal" RELATED SYSTEMATIC [AAO:0000847, UBERON:cjm] is_a: UBERON:0015049 ! carpus endochondral element is_a: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0015069 name: distal carpal cartilage element namespace: uberon def: "A distal carpal endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015068 ! distal carpal endochondral element is_a: UBERON:0018100 ! distal mesopodial cartilage element is_a: UBERON:0035128 ! manus cartilage element intersection_of: UBERON:0015068 ! distal carpal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0015077 name: centrale cartilage namespace: uberon def: "A centrale endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015064 ! autopod cartilage is_a: UBERON:0015067 ! centrale endochondral element intersection_of: UBERON:0015067 ! centrale endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0015078 name: proximal carpal endochondral element namespace: uberon def: "A proximal mesopodial endochondral element that is part of a forelimb." [OBOL:automatic] synonym: "proximal carpal" RELATED SYSTEMATIC [UBERON:cjm] synonym: "proximal carpal element" EXACT [UBERON:cjm] is_a: UBERON:0015049 ! carpus endochondral element is_a: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: part_of UBERON:0002102 ! forelimb [Term] id: UBERON:0015079 name: proximal carpal cartilage namespace: uberon def: "A proximal carpal endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015078 ! proximal carpal endochondral element is_a: UBERON:0017751 ! proximal mesopodial cartilage element is_a: UBERON:0035128 ! manus cartilage element intersection_of: UBERON:0015078 ! proximal carpal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0015080 ! proximal carpal bone pre-cartilage condensation [Term] id: UBERON:0015080 name: proximal carpal bone pre-cartilage condensation namespace: uberon def: "A proximal carpal endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015078 ! proximal carpal endochondral element intersection_of: UBERON:0015078 ! proximal carpal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0015081 name: proximal tarsal endochondral element namespace: uberon def: "A proximal mesopodial endochondral element that is part of a hindlimb." [OBOL:automatic] synonym: "proximal tarsal" RELATED SYSTEMATIC [UBERON:cjm] is_a: UBERON:0015050 ! tarsus endochondral element is_a: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0015082 name: proximal tarsal cartilage namespace: uberon def: "A proximal tarsal endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015081 ! proximal tarsal endochondral element is_a: UBERON:0017751 ! proximal mesopodial cartilage element is_a: UBERON:0035129 ! pes cartilage element intersection_of: UBERON:0015081 ! proximal tarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0015083 ! proximal tarsal bone pre-cartilage condensation [Term] id: UBERON:0015083 name: proximal tarsal bone pre-cartilage condensation namespace: uberon def: "A proximal tarsal endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0010886 ! hindlimb pre-cartilage condensation is_a: UBERON:0015081 ! proximal tarsal endochondral element intersection_of: UBERON:0015081 ! proximal tarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0015087 name: distal carpal bone 2 endochondral element namespace: uberon synonym: "distal carpal 2" RELATED SYSTEMATIC [UBERON:cjm] is_a: UBERON:0015049 ! carpus endochondral element [Term] id: UBERON:0015088 name: distal carpal bone 2 cartilage namespace: uberon def: "A distal carpal bone 2 endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015087 ! distal carpal bone 2 endochondral element is_a: UBERON:0035128 ! manus cartilage element intersection_of: UBERON:0015087 ! distal carpal bone 2 endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0015089 ! distal carpal bone 2 pre-cartilage condensation [Term] id: UBERON:0015089 name: distal carpal bone 2 pre-cartilage condensation namespace: uberon def: "A distal carpal bone 2 endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015087 ! distal carpal bone 2 endochondral element intersection_of: UBERON:0015087 ! distal carpal bone 2 endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0015090 name: distal carpal bone 3 endochondral element namespace: uberon synonym: "distal carpal 3" RELATED SYSTEMATIC [UBERON:cjm] is_a: UBERON:0015049 ! carpus endochondral element [Term] id: UBERON:0015091 name: distal carpal bone 3 cartilage namespace: uberon def: "A distal carpal bone 3 endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015090 ! distal carpal bone 3 endochondral element is_a: UBERON:0035128 ! manus cartilage element intersection_of: UBERON:0015090 ! distal carpal bone 3 endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0015092 ! distal carpal bone 3 pre-cartilage condensation [Term] id: UBERON:0015092 name: distal carpal bone 3 pre-cartilage condensation namespace: uberon def: "A distal carpal bone 3 endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015090 ! distal carpal bone 3 endochondral element intersection_of: UBERON:0015090 ! distal carpal bone 3 endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0015093 name: distal carpal bone 4 endochondral element namespace: uberon synonym: "distal carpal 4" RELATED SYSTEMATIC [UBERON:cjm] is_a: UBERON:0015049 ! carpus endochondral element [Term] id: UBERON:0015094 name: distal carpal bone 4 cartilage namespace: uberon def: "A distal carpal bone 4 endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015093 ! distal carpal bone 4 endochondral element is_a: UBERON:0035128 ! manus cartilage element intersection_of: UBERON:0015093 ! distal carpal bone 4 endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0015095 ! distal carpal bone 4 pre-cartilage condensation [Term] id: UBERON:0015095 name: distal carpal bone 4 pre-cartilage condensation namespace: uberon def: "A distal carpal bone 4 endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0010884 ! forelimb bone pre-cartilage condensation is_a: UBERON:0015093 ! distal carpal bone 4 endochondral element intersection_of: UBERON:0015093 ! distal carpal bone 4 endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0015099 name: distal tarsal endochondral element namespace: uberon def: "A distal mesopodial endochondral element that is part of a hindlimb." [OBOL:automatic] synonym: "distal tarsal" RELATED SYSTEMATIC [UBERON:cjm] is_a: UBERON:0015050 ! tarsus endochondral element is_a: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: part_of UBERON:0002103 ! hindlimb [Term] id: UBERON:0015100 name: distal tarsal cartilage namespace: uberon def: "A distal tarsal endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015099 ! distal tarsal endochondral element is_a: UBERON:0018100 ! distal mesopodial cartilage element is_a: UBERON:0035129 ! pes cartilage element intersection_of: UBERON:0015099 ! distal tarsal endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0015101 ! distal tarsal bone pre-cartilage condensation [Term] id: UBERON:0015101 name: distal tarsal bone pre-cartilage condensation namespace: uberon def: "A distal tarsal endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0010886 ! hindlimb pre-cartilage condensation is_a: UBERON:0015099 ! distal tarsal endochondral element is_a: UBERON:0018101 ! distal mesopodial pre-cartilage condensation intersection_of: UBERON:0015099 ! distal tarsal endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0015128 name: subepicardial layer of epicardium namespace: uberon synonym: "perimysial connective tissue of subepicardium" EXACT [FMA:83105] synonym: "subepicardial connective tissue" EXACT [FMA:83105] xref: FMA:83105 is_a: UBERON:0007188 ! mesothelium of serous pericardium relationship: part_of UBERON:0002348 {source="FMA"} ! epicardium property_value: editor_note "consider merging into myocardial compact layer" xsd:string [Term] id: UBERON:0015129 name: epicardial fat namespace: uberon def: "Visceral intrapericardial fat contiguous with the myocardial surface." [DOI:10.5935/abc.20130138] synonym: "epicardial adipose tissue" EXACT [] synonym: "pericardial adipose tissue" EXACT [] xref: FMA:9871 xref: SCTID:42267001 is_a: UBERON:0003837 ! thoracic segment connective tissue is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0035814 ! pericardial fat intersection_of: UBERON:0001013 ! adipose tissue intersection_of: adjacent_to UBERON:0002348 ! epicardium intersection_of: adjacent_to UBERON:0002425 ! visceral serous pericardium intersection_of: surrounds UBERON:0000948 ! heart relationship: adjacent_to UBERON:0002348 ! epicardium relationship: adjacent_to UBERON:0002425 ! visceral serous pericardium relationship: composed_primarily_of CL:1000309 ! epicardial adipocyte relationship: part_of UBERON:0015128 ! subepicardial layer of epicardium [Term] id: UBERON:0015152 name: gland of ocular region namespace: uberon def: "A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/614] synonym: "ocular gland" EXACT [] synonym: "orbital gland" RELATED [] is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0004088 ! orbital region relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: part_of UBERON:0035639 {source="inferred"} ! ocular adnexa property_value: UBPROP:0000008 "the only orbital gland found in anuran amphibians is either the Harderian or the lacrimal; if it is a lacrimal, then a progressive lateral migration of the lacrimal glands must occur through the amniotes[PMID:7559104]" xsd:string property_value: UBPROP:0000008 "the only orbital gland found in anuran amphibians is the Harderian[PMID:8843648]" xsd:string [Term] id: UBERON:0015165 name: multi-unit eye namespace: uberon def: "An eye consisting of multiple light-sensing organs." [http://orcid.org/0000-0002-6601-2165, PMID:21062451] is_a: UBERON:0000970 ! eye intersection_of: UBERON:0000970 ! eye intersection_of: composed_primarily_of UBERON:0000020 ! sense organ relationship: composed_primarily_of UBERON:0000020 ! sense organ property_value: RO:0002161 NCBITaxon:7742 property_value: RO:0002175 NCBITaxon:6340 {notes="present on tentacular crown", source="PMID:21062451"} property_value: RO:0002175 NCBITaxon:6544 {notes="present on mantle edge in arcacean Bivalvia", source="PMID:21062451"} property_value: RO:0002175 NCBITaxon:7588 {notes="The eyes (optic cushions) on the oral surface of Asteroida (Echinodermata), close to the base of the terminal tentacles, are also composed of a number of simple ocelli - as many as 80-200 in certain species", source="PMID:21062451"} [Term] id: UBERON:0015172 name: endometrial blood vessel namespace: uberon def: "A blood vessel that is part of a endometrium." [OBOL:automatic] subset: human_reference_atlas synonym: "blood vessel of endometrium" EXACT [] xref: SCTID:254200009 is_a: UBERON:0001981 ! blood vessel is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001295 ! endometrium relationship: part_of UBERON:0001295 ! endometrium property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0015178 name: somite border namespace: uberon def: "A region of somite adjacent to presomitic mesoderm." [http://orcid.org/0000-0002-6601-2165] subset: pheno_slim synonym: "inter-somited border" RELATED [] synonym: "intersomitic boundary" RELATED [] synonym: "intersomitic fissure" RELATED [] synonym: "intersomitic junction" RELATED [XAO:0004074] synonym: "segmental border" RELATED [] synonym: "somite boundary" RELATED [ZFA:0001462] xref: TAO:0001462 xref: XAO:0004074 xref: ZFA:0001462 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: adjacent_to UBERON:0003059 ! presomitic mesoderm intersection_of: part_of UBERON:0002329 ! somite relationship: adjacent_to UBERON:0003059 ! presomitic mesoderm relationship: part_of UBERON:0002329 ! somite [Term] id: UBERON:0015179 name: somite boundary epithelium namespace: uberon def: "Epithelium located in the intersomitic region." [XAO:0004077, XAO:EJS] synonym: "intersomitic epithelium" EXACT [XAO:0004077] synonym: "intersomitic membrane" EXACT [XAO:0004077] xref: XAO:0004077 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0015178 ! somite border relationship: part_of UBERON:0015178 ! somite border [Term] id: UBERON:0015180 name: neck of talus namespace: uberon def: "The neck of talus is directed forward and medialward, and comprises the constricted portion of the bone between the body and the oval head. Its upper and medial surfaces are rough, for the attachment of ligaments; its lateral surface is concave and is continuous below with the deep groove for the interosseous talocalcaneal ligament." [Wikipedia:Neck_of_talus] subset: human_reference_atlas subset: pheno_slim synonym: "collum tali" RELATED [Wikipedia:Neck_of_talus] synonym: "talar neck" EXACT [FMA:33636] synonym: "talus neck" EXACT [FMA:33636] xref: FMA:33636 xref: SCTID:182104001 xref: Wikipedia:Neck_of_talus is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0018664 ! neck of bone element intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0002395 ! talus relationship: part_of UBERON:0002395 ! talus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0015181 name: neck of tooth namespace: uberon def: "The slightly constricted part of a tooth, between the crown and the root." [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] synonym: "cervical margin of tooth" RELATED [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] synonym: "cervical zone of tooth" RELATED [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] synonym: "cervix dentis" EXACT LATIN [FMA:TA] synonym: "cervix of tooth" EXACT [FMA:55627] synonym: "collumn dentis" EXACT LATIN [ncithesaurus:Collum_Dentis] synonym: "dental neck" EXACT [http://www.medilexicon.com/medicaldictionary.php?s=neck+of+tooth] synonym: "tooth neck" EXACT [FMA:55627] xref: FMA:55627 xref: NCIT:C32346 xref: SCTID:28638008 is_a: UBERON:0001560 ! neck of organ is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0001091 ! calcareous tooth relationship: part_of UBERON:0001091 ! calcareous tooth [Term] id: UBERON:0015203 name: non-connected functional system namespace: uberon def: "An anatomical group whose component structures share a common function." [AEO:0000093, AEO:JB, FBbt:00007278, FBC:DOS] xref: AEO:0000093 xref: FBbt:00007278 is_a: UBERON:0034923 ! disconnected anatomical group [Term] id: UBERON:0015204 name: glandular system namespace: uberon def: "A non-connected functional system that is composed primarily of a gland." [OBOL:automatic] xref: EHDAA2:0002223 is_a: UBERON:0015203 ! non-connected functional system intersection_of: UBERON:0015203 ! non-connected functional system intersection_of: composed_primarily_of UBERON:0002530 ! gland relationship: composed_primarily_of UBERON:0002530 ! gland [Term] id: UBERON:0015212 name: lateral structure namespace: uberon def: "Any structure that is placed on one side of the left-right axis of a bilaterian." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class subset: non_informative is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: in_lateral_side_of UBERON:0000465 ! material anatomical entity relationship: in_lateral_side_of UBERON:0000465 ! material anatomical entity relationship: only_in_taxon NCBITaxon:33213 ! Bilateria relationship: part_of UBERON:0000465 ! material anatomical entity property_value: IAO:0000232 "This class is primarily to implement taxon constraints. It may be removed in the future." xsd:string [Term] id: UBERON:0015214 name: arcuate ligament namespace: uberon def: "A ligament that is part of a diaphragm." [OBOL:automatic] xref: EMAPA:19236 xref: FMA:58280 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000211 ! ligament is_a: UBERON:0005181 ! thoracic segment organ intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001103 ! diaphragm relationship: part_of UBERON:0001103 ! diaphragm [Term] id: UBERON:0015228 name: circulatory organ namespace: uberon def: "A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile." [http://orcid.org/0000-0002-6601-2165] subset: grouping_class synonym: "cardiac pump" EXACT [] synonym: "cardiac structure" RELATED [] synonym: "circulatory vessel" NARROW [] synonym: "heart" BROAD [] synonym: "heart or heart like organ" EXACT [] xref: SPD:0000130 is_a: UBERON:0003103 ! compound organ relationship: has_quality PATO:0001690 ! contractile relationship: part_of UBERON:0001009 ! circulatory system [Term] id: UBERON:0015249 name: digit skin namespace: uberon def: "A zone of skin that is part of a digit [Automatically generated definition]." [OBOL:automatic] subset: pheno_slim xref: EMAPA:32615 xref: MA:0003011 is_a: UBERON:0015790 ! autopod skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002544 ! digit relationship: part_of UBERON:0002544 ! digit [Term] id: UBERON:0015280 name: pancreas left lobe namespace: uberon def: "A pancreatic lobule that is in_the_left_side_of a exocrine pancreas." [OBOL:automatic] xref: EMAPA:37711 {source="MA:th"} xref: MA:0000722 is_a: UBERON:0007324 ! pancreatic lobule is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0007324 ! pancreatic lobule intersection_of: in_left_side_of UBERON:0000017 ! exocrine pancreas relationship: in_left_side_of UBERON:0000017 ! exocrine pancreas [Term] id: UBERON:0015281 name: pancreas right lobe namespace: uberon def: "A pancreatic lobule that is in_the_right_side_of a exocrine pancreas." [OBOL:automatic] xref: EMAPA:37712 {source="MA:th"} xref: MA:0000723 is_a: UBERON:0007324 ! pancreatic lobule is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0007324 ! pancreatic lobule intersection_of: in_right_side_of UBERON:0000017 ! exocrine pancreas relationship: in_right_side_of UBERON:0000017 ! exocrine pancreas [Term] id: UBERON:0015329 name: respiratory system basement membrane namespace: uberon def: "A basement membrane of epithelium that is part of a respiratory system." [OBOL:automatic] xref: EMAPA:37570 {source="MA:th"} xref: MA:0001815 is_a: UBERON:0005769 ! basement membrane of epithelium intersection_of: UBERON:0005769 ! basement membrane of epithelium intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0003570 {source="MA"} ! respiratory system connective tissue [Term] id: UBERON:0015410 name: heart plus pericardium namespace: uberon synonym: "heart/pericardium" EXACT [MA:0002449] xref: EMAPA:37597 {source="MA:th"} xref: MA:0002449 is_a: UBERON:0005178 {source="MA"} ! thoracic cavity element relationship: part_of UBERON:0004535 ! cardiovascular system [Term] id: UBERON:0015418 name: urethra mesenchymal layer namespace: uberon def: "A mesenchyme that is part of a urethra." [OBOL:automatic] xref: EMAPA:37786 {source="MA:th"} xref: MA:0002648 is_a: UBERON:0003104 ! mesenchyme is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 ! urethra [Term] id: UBERON:0015420 name: ureteral valve namespace: uberon def: "A valve that is part of a ureter." [OBOL:automatic] synonym: "ureteral valve" EXACT [MA:0002658] synonym: "valve or ureter" EXACT [] xref: EMAPA:37781 {source="MA:th"} xref: MA:0002658 is_a: UBERON:0003978 ! valve is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0003978 ! valve intersection_of: part_of UBERON:0000056 ! ureter relationship: capable_of GO:0035809 ! regulation of urine volume relationship: part_of UBERON:0000056 ! ureter [Term] id: UBERON:0015474 name: axilla skin namespace: uberon def: "A zone of skin that is part of a axilla." [OBOL:automatic] synonym: "axillary skin" EXACT [FMA:37322] synonym: "skin of axilla" EXACT [FMA:37322] xref: EMAPA:37349 {source="MA:th"} xref: FMA:37322 xref: MA:0003087 xref: NCIT:C116164 is_a: UBERON:8480025 ! skin of clavicle region intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0009472 ! axilla relationship: part_of UBERON:0009472 ! axilla [Term] id: UBERON:0015476 name: nose skin namespace: uberon def: "A zone of skin that is part of a external nose." [OBOL:automatic] synonym: "external nasal skin" EXACT [FMA:24763] synonym: "skin of external nose" EXACT [FMA:24763] synonym: "skin of nose" EXACT [FMA:24763] xref: EMAPA:37684 {source="MA:th"} xref: FMA:24763 xref: MA:0003090 is_a: UBERON:1000021 ! skin of face intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0007827 ! external nose relationship: part_of UBERON:0007827 ! external nose [Term] id: UBERON:0015480 name: proper hepatic artery namespace: uberon def: "The hepatic artery proper (also proper hepatic artery), arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. The hepatic artery proper gives off a small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently gives off the cystic artery, which feeds the gallbladder, before bifurcating into the right and left hepatic arteries. Of note, the right and left hepatic arteries may demonstrate variant anatomy. A replaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a replaced left hepatic artery may arise from the left gastric artery." [Wikipedia:Hepatic_artery_proper] subset: human_reference_atlas synonym: "hepatic artery proper" EXACT [FMA:14772] synonym: "proper hepatic" RELATED [Wikipedia:Hepatic_artery_proper] xref: EMAPA:37217 {source="MA:th"} xref: FMA:14772 xref: MA:0003095 xref: SCTID:244262006 xref: Wikipedia:Hepatic_artery_proper is_a: UBERON:0001193 {source="MA"} ! hepatic artery is_a: UBERON:0004573 ! systemic artery relationship: branching_part_of UBERON:0005436 {source="FMA"} ! common hepatic artery relationship: part_of UBERON:0005436 ! common hepatic artery property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0015481 name: left hepatic artery namespace: uberon def: "A hepatic artery that is part of a left lobe of liver." [OBOL:automatic] subset: human_reference_atlas synonym: "left branch of hepatic artery" EXACT [FMA:14779] synonym: "left part of hepatic artery proper" EXACT [FMA:14779] synonym: "ramus sinister (arteria hepatica propria)" EXACT LATIN [FMA:14779, FMA:TA] xref: EMAPA:37096 {source="MA:th"} xref: FMA:14779 xref: MA:0003096 is_a: UBERON:0001193 ! hepatic artery is_a: UBERON:0015796 ! liver blood vessel intersection_of: UBERON:0001193 ! hepatic artery intersection_of: part_of UBERON:0001115 ! left lobe of liver relationship: connected_to UBERON:0015480 ! proper hepatic artery relationship: part_of UBERON:0001115 {source="FMA"} ! left lobe of liver property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0015482 name: right hepatic artery namespace: uberon def: "A hepatic artery that is part of a right lobe of liver." [OBOL:automatic] subset: human_reference_atlas synonym: "ramus dexter (arteria hepatica propria)" EXACT LATIN [FMA:14778, FMA:TA] synonym: "right branch of hepatic artery proper" EXACT [FMA:14778] synonym: "right part of hepatic artery proper" EXACT [FMA:14778] xref: EMAPA:37376 {source="MA:th"} xref: FMA:14778 xref: MA:0003097 is_a: UBERON:0001193 ! hepatic artery is_a: UBERON:0015796 ! liver blood vessel intersection_of: UBERON:0001193 ! hepatic artery intersection_of: part_of UBERON:0001114 ! right lobe of liver relationship: connected_to UBERON:0015480 ! proper hepatic artery relationship: part_of UBERON:0001114 {source="FMA"} ! right lobe of liver property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0015485 name: choledocho-duodenal junction namespace: uberon def: "Hat part of the duodenal wall traversed by the ductus choledochus, ductus pancreaticus, and ampulla." [http://medical-dictionary.thefreedictionary.com/choledochoduodenal+junction] synonym: "choledochoduodenal junction" EXACT [MA:0003108] xref: EMAPA:37478 {source="MA:th"} xref: MA:0003108 is_a: UBERON:1100000 ! digestive tract junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0002114 ! duodenum intersection_of: connects UBERON:0002394 ! bile duct relationship: connects UBERON:0002114 ! duodenum relationship: connects UBERON:0002394 ! bile duct [Term] id: UBERON:0015716 name: anal canal epithelium namespace: uberon def: "An epithelium that is part of a anal canal." [OBOL:automatic] subset: human_reference_atlas synonym: "anal canal epithelium" EXACT [FMA:17511] synonym: "epithelium of anal canal" EXACT [FMA:17511] xref: EMAPA:18835 xref: FMA:17511 is_a: UBERON:0001278 ! epithelium of large intestine is_a: UBERON:0014703 ! anal membrane ectodermal component intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000159 ! anal canal relationship: part_of UBERON:0000159 ! anal canal property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0015717 name: smooth muscle tissue layer of ejaculatory duct namespace: uberon def: "A smooth muscle tissue that is part of a ejaculatory duct." [OBOL:automatic] synonym: "muscle layer of ejaculatory duct" EXACT [FMA:19372] xref: EMAPA:32289 xref: FMA:19372 is_a: UBERON:0001135 ! smooth muscle tissue is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0000999 ! ejaculatory duct relationship: part_of UBERON:0000999 ! ejaculatory duct [Term] id: UBERON:0015757 name: heterogeneous tissue namespace: uberon synonym: "portion of heterogeneous tissue" EXACT [FMA:62798] xref: FMA:62798 is_a: UBERON:0000479 {source="FMA"} ! tissue [Term] id: UBERON:0015783 name: smooth muscle layer in fatty layer of subcutaneous tissue namespace: uberon def: "A smooth muscle tissue that is part of a hypodermis." [OBOL:automatic] synonym: "muscle layer in fatty layer of subcutaneous tissue" EXACT [FMA:77862] synonym: "stratum musculosum panniculi adiposi telae subcutaneae" EXACT LATIN [FMA:77862, FMA:TA] xref: FMA:77862 is_a: UBERON:0001135 ! smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0002072 ! hypodermis relationship: part_of UBERON:0002072 ! hypodermis [Term] id: UBERON:0015787 name: upper respiratory conduit namespace: uberon def: "Any anatomical conduit which is part of the upper respiratory tract." [http://orcid.org/0000-0002-6601-2165] synonym: "respiratory conduit" RELATED [FMA:265132] xref: FMA:265132 is_a: UBERON:0004111 ! anatomical conduit is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: part_of UBERON:0001557 ! upper respiratory tract relationship: part_of UBERON:0001557 ! upper respiratory tract property_value: UBPROP:0000001 "Anatomical cluster which consists a segment of the upper respiratory tract[FMA:265132]." xsd:string {source="FMA:265132"} [Term] id: UBERON:0015788 name: olfactory apparatus chamber namespace: uberon def: "An anatomical chamber that is part of the olfactory apparatus, consisting of cavity walls (nasal epithelium and mucosal layers) and the space bounded anteriorly by the nares and posteriorly by the choanae, when these structures are present." [http://orcid.org/0000-0002-6601-2165] xref: FMA:265136 is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0015787 ! upper respiratory conduit relationship: part_of UBERON:0000004 ! nose [Term] id: UBERON:0015789 name: cranial or facial muscle namespace: uberon subset: grouping_class synonym: "cranial-facial muscle" RELATED [EMAPA:25133] synonym: "cranial/facial muscle" EXACT [MA:0000579] synonym: "cranio-facial muscle" RELATED [EMAPA:25133] synonym: "craniofacial muscle" RELATED [EMAPA:25133] xref: EMAPA:25133 xref: MA:0000579 is_a: UBERON:0002376 ! cranial muscle relationship: part_of UBERON:0004473 ! musculature of face property_value: IAO:0000232 "see also, 'facial nerve muscle', which is not precisely equivalent. We include this grouping to accomodate the MA class, which includes masticatory muscle as a subtype; note the masticatory muscle is noy innervated by the facial nerve, unlike the facial muscles proper" xsd:string [Term] id: UBERON:0015790 name: autopod skin namespace: uberon def: "A zone of skin that is part of a autopod region." [OBOL:automatic] synonym: "paw skin" RELATED [MA:0003120] xref: EMAPA:32723 xref: MA:0003120 is_a: UBERON:0001419 ! skin of limb intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0002470 ! autopod region relationship: part_of UBERON:0002470 ! autopod region [Term] id: UBERON:0015791 name: digit connective tissue namespace: uberon def: "A portion of connective tissue that is part of a digit." [OBOL:automatic] xref: EMAPA:37290 {source="MA:th"} xref: MA:0003123 is_a: UBERON:0003587 ! limb connective tissue intersection_of: UBERON:0002384 ! connective tissue intersection_of: part_of UBERON:0002544 ! digit relationship: develops_from UBERON:0010702 ! digit mesenchyme relationship: part_of UBERON:0002544 ! digit relationship: transformation_of UBERON:0010702 ! digit mesenchyme [Term] id: UBERON:0015796 name: liver blood vessel namespace: uberon def: "A blood vessel that is part of a liver." [OBOL:automatic] synonym: "hepatic blood vessel" RELATED [EMAPA:35498] xref: EMAPA:35498 xref: MA:0003137 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003497 ! abdomen blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 ! liver [Term] id: UBERON:0015807 name: ear epithelium namespace: uberon def: "An epithelium that is part of a ear." [OBOL:automatic] xref: EMAPA:32800 xref: MA:0003161 is_a: UBERON:0019304 ! sensory organ epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001690 ! ear relationship: part_of UBERON:0001690 ! ear [Term] id: UBERON:0015808 name: eye epithelium namespace: uberon def: "An epithelium that is part of a camera-type eye." [OBOL:automatic] xref: EMAPA:35957 xref: MA:0003162 is_a: UBERON:0007625 ! pigment epithelium of eye is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000019 ! camera-type eye relationship: part_of UBERON:0000019 ! camera-type eye [Term] id: UBERON:0015813 name: middle ear epithelium namespace: uberon def: "An epithelium that is part of a middle ear." [OBOL:automatic] xref: EMAPA:35673 xref: MA:0003169 is_a: UBERON:0015807 ! ear epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001756 ! middle ear relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0015814 name: outer ear epithelium namespace: uberon def: "An epithelium that is part of a external ear." [OBOL:automatic] xref: EMAPA:35956 xref: MA:0003170 is_a: UBERON:0015807 ! ear epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001691 ! external ear relationship: part_of UBERON:0001691 ! external ear [Term] id: UBERON:0015833 name: foregut epithelium namespace: uberon def: "An epithelium that is part of a foregut." [OBOL:automatic] xref: EMAPA:32922 xref: MA:0003204 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001041 ! foregut relationship: part_of UBERON:0001041 ! foregut [Term] id: UBERON:0015834 name: duodenum lamina propria namespace: uberon def: "A lamina propria that is part of a duodenum." [OBOL:automatic] subset: human_reference_atlas synonym: "duodenal lamina propria" EXACT [FMA:15972] synonym: "lamina propria mucosae of duodenum" EXACT [FMA:15972] synonym: "lamina propria of duodenum" EXACT [FMA:15972] xref: EMAPA:27255 xref: FMA:15972 xref: MA:0003209 is_a: UBERON:0001238 ! lamina propria of small intestine intersection_of: UBERON:0000030 ! lamina propria intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0008342 {source="FMA"} ! intestinal villus of duodenum property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0015837 name: incisor dental pulp namespace: uberon def: "A dental pulp that is part of a incisor tooth." [OBOL:automatic] xref: EMAPA:35429 xref: FMA:294459 xref: MA:0003221 is_a: UBERON:0001754 ! dental pulp intersection_of: UBERON:0001754 ! dental pulp intersection_of: part_of UBERON:0001098 ! incisor tooth relationship: part_of UBERON:0001098 ! incisor tooth property_value: UBPROP:0000012 "FMA has classes for very specific sublcasses but no generic grouping at this level" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0015838 name: molar dental pulp namespace: uberon xref: EMAPA:35576 xref: FMA:294469 xref: MA:0003222 is_a: UBERON:0001754 ! dental pulp intersection_of: UBERON:0001754 ! dental pulp intersection_of: part_of UBERON:0003655 ! molar tooth relationship: part_of UBERON:0003655 ! molar tooth property_value: UBPROP:0000012 "FMA has classes for very specific sublcasses but no generic grouping at this level" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0015839 name: molar epithelium namespace: uberon synonym: "epithelium of molar" EXACT [] synonym: "epithelium of molar tooth" EXACT [] xref: EMAPA:32878 xref: MA:0003224 is_a: UBERON:0003843 ! dental epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0003655 ! molar tooth relationship: part_of UBERON:0003655 ! molar tooth [Term] id: UBERON:0015842 name: incisor enamel organ namespace: uberon def: "A tooth enamel organ that is part of a incisor tooth." [OBOL:automatic] xref: EMAPA:32895 xref: MA:0003227 is_a: UBERON:0005176 ! tooth enamel organ intersection_of: UBERON:0005176 ! tooth enamel organ intersection_of: part_of UBERON:0001098 ! incisor tooth relationship: part_of UBERON:0003355 ! epithelium of incisor [Term] id: UBERON:0015843 name: molar enamel organ namespace: uberon xref: EMAPA:32880 xref: MA:0003228 is_a: UBERON:0005176 ! tooth enamel organ intersection_of: UBERON:0005176 ! tooth enamel organ intersection_of: part_of UBERON:0003655 ! molar tooth relationship: part_of UBERON:0015839 ! molar epithelium [Term] id: UBERON:0015844 name: molar dental papilla namespace: uberon synonym: "molar odontogenic papilla" EXACT [OBOL:automatic] synonym: "molar tooth odontogenic papilla" EXACT [OBOL:automatic] xref: EMAPA:32882 xref: MA:0003232 is_a: UBERON:0001763 ! odontogenic papilla intersection_of: UBERON:0001763 ! odontogenic papilla intersection_of: part_of UBERON:0003655 ! molar tooth relationship: develops_from UBERON:0011641 ! odontogenic mesenchyme of molar relationship: part_of UBERON:0003655 ! molar tooth [Term] id: UBERON:0015846 name: incisor mesenchyme namespace: uberon def: "An odontogenic mesenchyme that is part of a incisor tooth." [OBOL:automatic] xref: EMAPA:32894 xref: MA:0003229 is_a: UBERON:0003856 ! uncondensed odontogenic mesenchyme intersection_of: UBERON:0003856 ! uncondensed odontogenic mesenchyme intersection_of: part_of UBERON:0001098 ! incisor tooth relationship: part_of UBERON:0001098 ! incisor tooth [Term] id: UBERON:0015847 name: upper left incisor tooth namespace: uberon def: "A upper jaw incisor that is in_the_left_side_of a dentition." [OBOL:automatic] xref: SCTID:245585000 is_a: UBERON:0003450 ! upper jaw incisor is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0003450 ! upper jaw incisor intersection_of: in_left_side_of UBERON:0003672 ! dentition relationship: in_left_side_of UBERON:0003672 ! dentition [Term] id: UBERON:0015873 name: heel skin namespace: uberon def: "A zone of skin that is part of a heel." [OBOL:automatic] synonym: "skin of heel" EXACT [] xref: EMAPA:37354 {source="MA:th"} xref: MA:0003104 xref: SCTID:244185002 is_a: UBERON:0001512 ! skin of ankle intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0015875 ! heel relationship: part_of UBERON:0015875 ! heel [Term] id: UBERON:0015875 name: heel namespace: uberon def: "The part of the foot that is the projection of the calcaneus." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Heel] synonym: "calcaneal region" EXACT [FMA:24994] synonym: "heel region" EXACT [FMA:24994] synonym: "regio calcanea" EXACT [FMA:TA] xref: FMA:24994 xref: MESH:D006365 xref: SCTID:362804005 xref: Wikipedia:Heel is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0005445 ! segment of pes intersection_of: UBERON:0005445 ! segment of pes intersection_of: has_skeleton UBERON:0001450 ! calcaneus relationship: has_skeleton UBERON:0001450 ! calcaneus relationship: part_of UBERON:0004454 ! tarsal region [Term] id: UBERON:0016404 name: cervical vertebral arch joint namespace: uberon def: "A vertebral arch joint that is part of a cervical region of vertebral column." [OBOL:automatic] subset: pheno_slim synonym: "cervical facet joint" EXACT [FMA:13668] synonym: "joint of cervical vertebral arch" EXACT [FMA:13668] synonym: "joint of cervical vertebral articular process" EXACT [FMA:13668] synonym: "zygapophyseal joint of cervical vertebrae" EXACT [FMA:13668] synonym: "zygapophysial joint of cervical vertebrae" EXACT [FMA:13668] xref: FMA:13668 is_a: UBERON:0001067 ! vertebral arch joint intersection_of: UBERON:0001067 ! vertebral arch joint intersection_of: part_of UBERON:0006072 ! cervical region of vertebral column relationship: part_of UBERON:0006072 ! cervical region of vertebral column [Term] id: UBERON:0016405 name: pulmonary capillary namespace: uberon def: "A capillary that is part of a lung." [OBOL:automatic] subset: human_reference_atlas subset: pheno_slim synonym: "capillary of lung" EXACT [FMA:14121] xref: FMA:14121 is_a: UBERON:0003512 ! lung blood vessel is_a: UBERON:0003526 ! respiratory system capillary intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0002048 ! lung property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0016418 name: nasion namespace: uberon def: "The intersection of the frontal and two nasal bones of the human skull. Its manifestation on the visible surface of the face is a distinctly depressed area directly between the eyes, just superior to the bridge of the nose." [Wikipedia:Nasion] subset: pheno_slim xref: FMA:264779 xref: Wikipedia:Nasion is_a: UBERON:0006983 ! anatomical point intersection_of: UBERON:0006983 ! anatomical point intersection_of: connects UBERON:0000209 ! tetrapod frontal bone intersection_of: connects UBERON:0006813 ! nasal skeleton relationship: connects UBERON:0000209 ! tetrapod frontal bone relationship: connects UBERON:0006813 ! nasal skeleton relationship: part_of UBERON:0003129 ! skull [Term] id: UBERON:0016426 name: proximal interphalangeal joint of little finger namespace: uberon subset: pheno_slim xref: FMA:35324 is_a: UBERON:0007732 ! interphalangeal joint of manual digit 5 is_a: UBERON:0009767 ! proximal interphalangeal joint intersection_of: UBERON:0009767 ! proximal interphalangeal joint intersection_of: part_of UBERON:0003625 ! manual digit 5 [Term] id: UBERON:0016442 name: median palatine suture namespace: uberon def: "The line of junction between the horizontal parts of the palatine bones that extends from both sides of the skull to form the posterior part of the hard palate." [http://medical-dictionary.thefreedictionary.com/median+palatine+suture] subset: pheno_slim synonym: "median palatine suture of skull" EXACT [FMA:52966] synonym: "middle palatine suture of skull" EXACT [FMA:52966] synonym: "midpalatal suture of skull" EXACT [FMA:52966] xref: FMA:52966 is_a: UBERON:0035127 ! suture of hard palate intersection_of: UBERON:0035127 ! suture of hard palate intersection_of: connects UBERON:0001682 {cardinality="2"} ! palatine bone relationship: connects UBERON:0001682 ! palatine bone [Term] id: UBERON:0016452 name: upper secondary premolar tooth namespace: uberon subset: pheno_slim synonym: "maxillary secondary premolar tooth" EXACT [FMA:55716] synonym: "permanent upper premolar tooth" RELATED [FMA:55716] synonym: "secondary upper premolar tooth" RELATED [FMA:55716] synonym: "upper permanent premolar tooth" EXACT [FMA:55716] xref: FMA:55716 is_a: UBERON:0016944 ! upper premolar tooth is_a: UBERON:0017270 ! secondary premolar tooth is_a: UBERON:0018613 ! secondary upper tooth intersection_of: UBERON:0017270 ! secondary premolar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0016453 name: lower secondary premolar tooth namespace: uberon subset: pheno_slim synonym: "lower permanent premolar tooth" EXACT [FMA:55717] synonym: "mandibular secondary premolar tooth" EXACT [FMA:55717] synonym: "permanent lower premolar tooth" RELATED [FMA:55717] xref: FMA:55717 is_a: UBERON:0016943 ! lower premolar tooth is_a: UBERON:0017270 ! secondary premolar tooth is_a: UBERON:0018614 ! permanent lower tooth intersection_of: UBERON:0017270 ! secondary premolar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0016454 name: upper central secondary incisor tooth namespace: uberon subset: pheno_slim synonym: "I1" RELATED ABBREVIATION [] synonym: "maxillary central permanent incisor tooth" EXACT [] synonym: "maxillary central secondary incisor tooth" EXACT [FMA:55722] synonym: "permanent upper central incisor tooth" RELATED [FMA:55722] synonym: "upper central permanent incisor tooth" EXACT [FMA:55722] xref: FMA:55722 is_a: UBERON:0018603 ! upper central incisor tooth is_a: UBERON:0019253 ! upper secondary incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0016455 name: upper lateral secondary incisor tooth namespace: uberon subset: pheno_slim synonym: "I2" RELATED ABBREVIATION [] synonym: "maxillary lateral secondary incisor tooth" EXACT [FMA:55724] synonym: "upper lateral permanent incisor tooth" EXACT [FMA:55724] xref: FMA:55724 is_a: UBERON:0018604 ! upper lateral incisor tooth is_a: UBERON:0019253 ! upper secondary incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: seeAlso "https://github.com/obophenotype/uberon/issues/557" xsd:anyURI [Term] id: UBERON:0016458 name: esophageal hiatus namespace: uberon def: "A hole in the diaphragm through which the esophagus passes." [HP:0002036] subset: pheno_slim synonym: "esophageal hiatus of diaphragm" EXACT [FMA:58289] synonym: "oesophageal aperture" EXACT [FMA:58289] synonym: "oesophageal hiatus" EXACT [FMA:58289] xref: FMA:58289 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000161 ! orifice intersection_of: UBERON:0000161 ! orifice intersection_of: conduit_for UBERON:0001043 ! esophagus intersection_of: part_of UBERON:0001103 ! diaphragm relationship: conduit_for UBERON:0001043 ! esophagus relationship: part_of UBERON:0001103 ! diaphragm [Term] id: UBERON:0016467 name: antitragus namespace: uberon def: "The antitragus is a feature of human ear anatomy. It is a small tubercle that points anteriorly. It is separated from the tragus by the intertragic notch." [Wikipedia:Antitragus] subset: pheno_slim synonym: "antitragal part of pinna" EXACT [FMA:61001] xref: FMA:61001 xref: NCIT:C32121 xref: SCTID:362543000 xref: UMLS:C0229314 xref: Wikipedia:Antitragus is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000481 ! multi-tissue structure relationship: develops_from UBERON:0016612 {source="http://php.med.unsw.edu.au"} ! auditory hillocks, pharyngeal arch 2 derived relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0001757 {source="FMA"} ! pinna [Term] id: UBERON:0016476 name: primary incisor tooth namespace: uberon def: "An incisor tooth that is part of a primary dentition." [OBOL:automatic] subset: pheno_slim synonym: "deciduous incisor tooth" EXACT [FMA:84200] synonym: "temporary incisor tooth" EXACT [FMA:84200] xref: FMA:84200 xref: SCTID:51528000 is_a: UBERON:0001098 ! incisor tooth is_a: UBERON:0007115 ! deciduous tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0016478 name: liver stroma namespace: uberon def: "A stroma that is part of a liver." [OBOL:automatic] subset: human_reference_atlas synonym: "hepatic stroma" EXACT [FMA:17553] synonym: "stroma of liver" EXACT [FMA:17553] xref: FMA:17553 is_a: UBERON:0003891 ! stroma is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0002107 ! liver relationship: part_of UBERON:0002107 ! liver property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0016490 name: auditory system namespace: uberon def: "Is the sensory system for the sense of hearing." [NLXANAT:090817] xref: EMAPA:36002 xref: FMA:7192 xref: MA:0002443 xref: NCIT:C12889 xref: neuronames:2888 xref: NLXANAT:090817 xref: UMLS:C0587901 {source="ncithesaurus:Auditory_System"} xref: Wikipedia:Auditory_system is_a: UBERON:0007037 ! mechanosensory system intersection_of: UBERON:0001032 ! sensory system intersection_of: capable_of GO:0007605 ! sensory perception of sound relationship: capable_of GO:0007605 ! sensory perception of sound relationship: part_of UBERON:0002105 ! vestibulo-auditory system property_value: UBPROP:0000012 "Auditory system is general anatomical term in FMA" xsd:string {external_ontology="FMA"} [Term] id: UBERON:0016491 name: vertebral centrum element namespace: uberon def: "Skeletal element that functionally replaces the notochord[VSAP,modified]." [http://orcid.org/0000-0002-6601-2165, https://github.com/obophenotype/uberon/issues/207, https://github.com/obophenotype/uberon/issues/80, VSAO:0000183, VSAO:curator] synonym: "centrum" BROAD [VSAO:0000183] synonym: "centrum of vertebra" EXACT [] xref: VSAO:0000183 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004765 {source="VSAO"} ! skeletal element relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: part_of UBERON:0010913 {source="VSAO"} ! vertebral element property_value: UBPROP:0000001 "Skeletal element that surrounds the notochord.[VSAO]" xsd:string {date_retrieved="2012-08-14", external_class="VSAO:0000183", ontology="VSAO", source="VSAO:curator"} property_value: UBPROP:0000001 "the main cylindrical portion of the vertebra ventral to the vertebral canal" xsd:string {source="MP:0000141,ISBN:0-683-40008-8,PMID:10572046"} property_value: UBPROP:0000008 "The vertebral centrum may be cartilaginous, develop as cartilage but be replaced by bone or mineralized, or form directly through intramembranous ossification." xsd:string [Term] id: UBERON:0016509 name: cavity of right ventricle namespace: uberon def: "Luminal space of the right ventricle of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "right ventricle lumen" EXACT [EMAPA:26047] synonym: "right ventricular cavity" EXACT [FMA:FMA] xref: EMAPA:26047 xref: FMA:9291 is_a: UBERON:0035763 ! cavity of cardiac chamber intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002080 ! heart right ventricle relationship: luminal_space_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0002080 ! heart right ventricle [Term] id: UBERON:0016510 name: epithelium of male urethra namespace: uberon def: "An epithelium that is part of a male urethra." [OBOL:automatic] synonym: "male urethral epithelium" EXACT [FMA:FMA] synonym: "urethral epithelium of male" EXACT [EMAPA:30467] xref: EMAPA:30467 xref: FMA:19684 is_a: UBERON:0002325 ! epithelium of urethra intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001333 ! male urethra relationship: part_of UBERON:0001333 ! male urethra [Term] id: UBERON:0016512 name: lumen of duodenum namespace: uberon def: "An anatomical space that is part of a duodenum." [OBOL:automatic] synonym: "doudenal lumen" EXACT [FMA:FMA] synonym: "duodenal lumen" EXACT [FMA:FMA] xref: EMAPA:19080 xref: FMA:14589 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: part_of UBERON:0002114 ! duodenum relationship: part_of UBERON:0002114 ! duodenum [Term] id: UBERON:0016513 name: cavity of left atrium namespace: uberon def: "Luminal space of the left atrium of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "left atrial cavity" EXACT [FMA:FMA] synonym: "left atrium lumen" EXACT [EMAPA:26011] xref: EMAPA:26011 xref: FMA:9465 is_a: UBERON:0035763 ! cavity of cardiac chamber intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002079 ! left cardiac atrium relationship: luminal_space_of UBERON:0002079 ! left cardiac atrium relationship: part_of UBERON:0002079 ! left cardiac atrium [Term] id: UBERON:0016514 name: cavity of left ventricle namespace: uberon def: "Luminal space of the left ventricle of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "left ventricular cavity" EXACT [FMA:FMA] xref: EMAPA:26038 xref: FMA:9466 is_a: UBERON:0035763 ! cavity of cardiac chamber intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002084 ! heart left ventricle relationship: luminal_space_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 ! heart left ventricle [Term] id: UBERON:0016520 name: epithelium of female urethra namespace: uberon def: "An epithelium that is part of a female urethra." [OBOL:automatic] synonym: "female urethral epithelium" EXACT [FMA:FMA] synonym: "urethral epithelium of female" EXACT [EMAPA:30470] xref: EMAPA:30470 xref: FMA:19774 is_a: UBERON:0002325 ! epithelium of urethra intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001334 ! female urethra relationship: part_of UBERON:0001334 ! female urethra [Term] id: UBERON:0016522 name: cavity of right atrium namespace: uberon def: "Luminal space of the right atrium of the heart." [http://orcid.org/0000-0002-6601-2165] synonym: "right atrial cavity" EXACT [FMA:FMA] xref: EMAPA:26020 xref: FMA:11359 is_a: UBERON:0035763 ! cavity of cardiac chamber intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0002078 ! right cardiac atrium relationship: luminal_space_of UBERON:0002078 ! right cardiac atrium relationship: part_of UBERON:0002078 ! right cardiac atrium [Term] id: UBERON:0016545 name: pharyngeal ectoderm namespace: uberon alt_id: UBERON:2001379 def: "The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches." [http://orcid.org/0000-0002-6601-2165, PMID:23020903] xref: TAO:0001379 xref: ZFA:0001379 is_a: UBERON:0000490 ! unilaminar epithelium is_a: UBERON:0003351 ! pharyngeal epithelium is_a: UBERON:0005291 ! embryonic tissue intersection_of: UBERON:0000490 ! unilaminar epithelium intersection_of: part_of UBERON:0000076 ! external ectoderm intersection_of: part_of UBERON:0001042 ! chordate pharynx relationship: part_of UBERON:0000076 ! external ectoderm [Term] id: UBERON:0016548 name: central nervous system gray matter layer namespace: uberon def: "A layer of of the central nervous system that is part of gray matter." [http://orcid.org/0000-0002-6601-2165] synonym: "CNS gray matter layer" EXACT [] synonym: "CNS grey matter layer" EXACT [] synonym: "gray matter layer of neuraxis" EXACT [FMA:83142] synonym: "grey matter layer" BROAD [] synonym: "grey matter layer of neuraxis" EXACT [] xref: FMA:83142 is_a: UBERON:0022303 ! nervous system cell part layer intersection_of: UBERON:0022303 ! nervous system cell part layer intersection_of: composed_primarily_of UBERON:0002020 ! gray matter relationship: composed_primarily_of UBERON:0002020 ! gray matter [Term] id: UBERON:0016549 name: central nervous system white matter layer namespace: uberon def: "A layer of of the central nervous system that is composed of white matter." [http://orcid.org/0000-0002-6601-2165] synonym: "CNS white matter layer" EXACT [] synonym: "white matter layer" BROAD [] synonym: "white matter layer of neuraxis" EXACT [FMA:83898] xref: FMA:83898 is_a: UBERON:0022303 ! nervous system cell part layer intersection_of: UBERON:0022303 ! nervous system cell part layer intersection_of: composed_primarily_of UBERON:0002316 ! white matter relationship: composed_primarily_of UBERON:0002316 ! white matter [Term] id: UBERON:0016550 name: spinal cord column namespace: uberon is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: part_of UBERON:0002240 ! spinal cord [Term] id: UBERON:0016552 name: phlegm namespace: uberon def: "Mucus produced in the respiratory tract." [http://orcid.org/0000-0002-6601-2165] xref: NCIT:C93171 xref: UMLS:C0225378 is_a: UBERON:0000912 ! mucus intersection_of: UBERON:0000912 ! mucus intersection_of: produced_by UBERON:0000065 ! respiratory tract relationship: produced_by UBERON:0000065 ! respiratory tract [Term] id: UBERON:0016553 name: respiratory system mucus namespace: uberon def: "Any mucus produced by a mucosae of the respiratory system. This includes the mucus produced in the nasal cavity (nasal mucus) and mucus produced in the respiratory tract (phlegm)." [http://orcid.org/0000-0002-6601-2165, Wikipedia:Nasal_mucus#Respiratory_system] is_a: UBERON:0000912 ! mucus intersection_of: UBERON:0000912 ! mucus intersection_of: produced_by UBERON:0004785 ! respiratory system mucosa relationship: produced_by UBERON:0004785 ! respiratory system mucosa [Term] id: UBERON:0016554 name: white matter of midbrain namespace: uberon def: "A white matter that is part of the midbrain." [OBOL:automatic] subset: human_reference_atlas synonym: "mesencephalic white matter" EXACT [HBA:MESWM] xref: DHBA:10650 xref: FMA:83936 xref: HBA:265505382 is_a: UBERON:0003544 ! brain white matter intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0001891 ! midbrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0016566 name: pit namespace: uberon def: "An roughly circular indentation in a surface." [AEO:0000204, AEO:JB] subset: upper_level xref: AEO:0000204 is_a: UBERON:0036215 ! anatomical surface region [Term] id: UBERON:0016570 name: lamina of gray matter of spinal cord namespace: uberon synonym: "rexed lamina" EXACT [FMA:68861] xref: FMA:68861 xref: http://neurolex.org/wiki/Category\:Rexed_spinal_cord_parcellation_scheme_region xref: Wikipedia:Rexed_laminae is_a: UBERON:0011215 ! central nervous system cell part cluster is_a: UBERON:0022303 ! nervous system cell part layer intersection_of: UBERON:0022303 ! nervous system cell part layer intersection_of: part_of UBERON:0002315 ! gray matter of spinal cord relationship: part_of UBERON:0002315 ! gray matter of spinal cord [Term] id: UBERON:0016611 name: auditory hillocks, pharyngeal arch 1 derived namespace: uberon def: "A collection of protruberances derived from pharyngeal arch 1 that develop into the tragus, crus of the helix, and helix." [http://php.med.unsw.edu.au/embryology/index.php?title=Hearing_-_Outer_Ear_Development#Pinna-_Auricle] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000477 ! anatomical cluster intersection_of: UBERON:0000477 ! anatomical cluster intersection_of: develops_from UBERON:0004362 ! pharyngeal arch 1 intersection_of: part_of UBERON:0006208 ! auditory hillocks relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 relationship: part_of UBERON:0006208 ! auditory hillocks [Term] id: UBERON:0016612 name: auditory hillocks, pharyngeal arch 2 derived namespace: uberon def: "A collection of protruberances derived from pharyngeal arch 2 that develop into the concha, antihelix and antitragus." [http://php.med.unsw.edu.au/embryology/index.php?title=Hearing_-_Outer_Ear_Development#Pinna-_Auricle] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000477 ! anatomical cluster intersection_of: UBERON:0000477 ! anatomical cluster intersection_of: develops_from UBERON:0003066 ! pharyngeal arch 2 intersection_of: part_of UBERON:0006208 ! auditory hillocks relationship: develops_from UBERON:0003066 ! pharyngeal arch 2 relationship: part_of UBERON:0006208 ! auditory hillocks [Term] id: UBERON:0016854 name: dorsal part of optic cup namespace: uberon def: "The dorsal region of the optic cup that gives rise to the dorsal part of the retina." [http://orcid.org/0000-0002-6601-2165] synonym: "dorsal optic cup" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "dorsal region of optic cup" EXACT [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000481 ! multi-tissue structure intersection_of: in_dorsal_side_of UBERON:0003072 ! optic cup relationship: in_dorsal_side_of UBERON:0003072 ! optic cup relationship: part_of UBERON:0003072 ! optic cup [Term] id: UBERON:0016879 name: future central nervous system namespace: uberon alt_id: UBERON:3000469 def: "Primordium that develops into the central nervous system." [http://orcid.org/0000-0002-6601-2165] synonym: "future CNS" EXACT [] synonym: "presumptive central nervous system" EXACT [] is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001017 ! central nervous system relationship: develops_from UBERON:0000924 ! ectoderm relationship: develops_from UBERON:0002346 {gci_relation="part_of", gci_filler="NCBITaxon:7742"} ! neurectoderm relationship: has_potential_to_develop_into UBERON:0001017 ! central nervous system relationship: part_of UBERON:0016880 ! future nervous system [Term] id: UBERON:0016880 name: future nervous system namespace: uberon alt_id: UBERON:3000477 def: "Primordium that develops into the nervous system." [http://orcid.org/0000-0002-6601-2165] synonym: "presumptive nervous system" EXACT [AAO:0000477] xref: AAO:0000477 is_a: UBERON:0006598 ! presumptive structure intersection_of: UBERON:0006598 ! presumptive structure intersection_of: has_potential_to_develop_into UBERON:0001016 ! nervous system relationship: existence_starts_during_or_after UBERON:0000111 ! organogenesis stage relationship: has_potential_to_develop_into UBERON:0001016 ! nervous system [Term] id: UBERON:0016884 name: shoulder joint namespace: uberon def: "The joint that is formed by the union of the humerus, the scapula (or shoulder blade), and the clavicle (or collarbone). Commonly thought of as a single joint, the shoulder is actually made up of two separate joints - the glenohumeral and acromioclavicular joints." [http://www.innerbody.com/image/skel17.html] synonym: "joint of shoulder region" EXACT [] xref: MESH:D012785 xref: SCTID:361835002 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: part_of UBERON:0001467 ! shoulder relationship: develops_from UBERON:0006292 {evidence="definitional"} ! shoulder joint primordium relationship: part_of UBERON:0001467 ! shoulder [Term] id: UBERON:0016885 name: epithelium of terminal part of digestive tract namespace: uberon def: "Epithelium lining the distalmost portion of the digestive tract." [http://orcid.org/0000-0002-6601-2165] synonym: "rectum epithelium" NARROW [BTO:0005445] xref: BTO:0005445 xref: WBbt:0005800 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0006866 ! terminal part of digestive tract relationship: part_of UBERON:0006866 ! terminal part of digestive tract [Term] id: UBERON:0016886 name: muscle tissue of terminal part of digestive tract namespace: uberon def: "Any muscle tissue of the distalmost portion of the digestive tract." [http://orcid.org/0000-0002-6601-2165] synonym: "rectum muscle" NARROW [] synonym: "rectum muscle structure" NARROW [] is_a: UBERON:0002385 ! muscle tissue intersection_of: UBERON:0002385 ! muscle tissue intersection_of: part_of UBERON:0006866 ! terminal part of digestive tract relationship: part_of UBERON:0006866 ! terminal part of digestive tract [Term] id: UBERON:0016887 name: entire extraembryonic component namespace: uberon def: "The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism." [AEO:0000195, AEO:JB] synonym: "extra-embryonic component" EXACT [] synonym: "extraembryonic component" EXACT [AEO:0000195] xref: AEO:0000195 xref: EHDAA2:0000003 xref: EMAPA:16042 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000481 {source="AEO"} ! multi-tissue structure relationship: adjacent_to UBERON:0002050 ! embryonic structure relationship: existence_starts_and_ends_during UBERON:0000068 ! embryo stage relationship: part_of UBERON:0004716 {source="AEO"} ! conceptus [Term] id: UBERON:0016888 name: transitional anatomical structure namespace: uberon def: "An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development." [AEO:0000132, AEO:JB] xref: AEO:0000132 is_a: UBERON:0005423 {source="AEO"} ! developing anatomical structure [Term] id: UBERON:0016928 name: metaphysis of fibula namespace: uberon def: "A metaphysis that is part of a fibula." [UBERON:nv] synonym: "fibula metaphysis" EXACT [FMA:33745] synonym: "fibular metaphysis" EXACT [] xref: FMA:33745 is_a: UBERON:0001438 ! metaphysis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001438 ! metaphysis intersection_of: part_of UBERON:0001446 ! fibula relationship: part_of UBERON:0001446 ! fibula [Term] id: UBERON:0016943 name: lower premolar tooth namespace: uberon alt_id: UBERON:4200143 synonym: "lower premolar tooth" EXACT [] synonym: "LP" BROAD ABBREVIATION [] synonym: "mandibular premolar tooth" EXACT [] is_a: UBERON:0003268 ! tooth of lower jaw is_a: UBERON:0007120 ! premolar tooth intersection_of: UBERON:0007120 ! premolar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0016944 name: upper premolar tooth namespace: uberon alt_id: UBERON:4200144 synonym: "maxillary premolar tooth" EXACT [] synonym: "UP" BROAD ABBREVIATION [] synonym: "upper premolar tooth" EXACT [] is_a: UBERON:0003267 ! tooth of upper jaw is_a: UBERON:0007120 ! premolar tooth intersection_of: UBERON:0007120 ! premolar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0017163 name: skin bony tubercle namespace: uberon def: "A bony structure embedded in skin, roughly equivalent to osteoderms." [PHENOSCAPE:Nizar] synonym: "bony tubercle" BROAD [] synonym: "bony tubercles" RELATED PLURAL [UBERONTEMP:3b77fb04-1e62-43af-a84b-5d5eb7388525] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005813 ! tubercle is_a: UBERON:0013703 ! integumentary projection intersection_of: UBERON:0005813 ! tubercle intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue intersection_of: part_of UBERON:0002199 ! integument relationship: composed_primarily_of UBERON:0002481 ! bone tissue relationship: part_of UBERON:0002199 ! integument [Term] id: UBERON:0017261 name: intertarsal sesamoid namespace: uberon def: "A sesamoid element that is part of a tarsal skeleton." [OBOL:automatic] synonym: "tarsal sesamoid" RELATED [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0011141 ! appendicular ossicle is_a: UBERON:0013631 ! sesamoid element intersection_of: UBERON:0013631 ! sesamoid element intersection_of: part_of UBERON:0009879 ! tarsal skeleton relationship: part_of UBERON:0009879 ! tarsal skeleton [Term] id: UBERON:0017269 name: primary premolar tooth namespace: uberon synonym: "deciduous premolar tooth" EXACT [] synonym: "primary bicuspid" RELATED [] synonym: "primary premolar" EXACT [] xref: SCTID:421227007 is_a: UBERON:0007115 ! deciduous tooth is_a: UBERON:0007120 ! premolar tooth intersection_of: UBERON:0007120 ! premolar tooth intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0017270 name: secondary premolar tooth namespace: uberon synonym: "permanent premolar tooth" EXACT [] synonym: "secondary bicuspid" RELATED [] synonym: "secondary premolar" EXACT [] xref: SCTID:422038004 is_a: UBERON:0007120 ! premolar tooth is_a: UBERON:0007775 ! secondary tooth intersection_of: UBERON:0007120 ! premolar tooth intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0017271 name: upper primary premolar tooth namespace: uberon synonym: "maxillary primary premolar tooth" EXACT [] synonym: "upper deciduous premolar tooth" EXACT [] is_a: UBERON:0016944 ! upper premolar tooth is_a: UBERON:0017269 ! primary premolar tooth is_a: UBERON:0018616 ! primary upper tooth intersection_of: UBERON:0007120 ! premolar tooth intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0017272 name: lower primary premolar tooth namespace: uberon synonym: "lower deciduous premolar tooth" EXACT [] synonym: "mandibular primary premolar tooth" EXACT [] is_a: UBERON:0016943 ! lower premolar tooth is_a: UBERON:0017269 ! primary premolar tooth is_a: UBERON:0018617 ! primary lower tooth intersection_of: UBERON:0007120 ! premolar tooth intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0017615 name: vomerine dentition namespace: uberon def: "A set of teeth in which each tooth that attaches to a vomer." [OBOL:automatic] synonym: "vomerine teeth" RELATED [] xref: AAO:0000635 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0003672 ! dentition intersection_of: UBERON:0003672 ! dentition intersection_of: attaches_to UBERON:0002396 ! vomer relationship: attaches_to UBERON:0002396 ! vomer relationship: part_of RO:0002577 ! system [Term] id: UBERON:0017649 name: dorsal body wall namespace: uberon def: "The dorsal part of the body wall." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0000309 ! body wall intersection_of: UBERON:0000309 ! body wall intersection_of: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0001137 ! dorsum [Term] id: UBERON:0017650 name: developing mesenchymal structure namespace: uberon def: "A mesenchyme-derived anatomical entity undergoing a transtion to become another structure." [AEO:0001016, AEO:JB] xref: AEO:0001016 is_a: UBERON:0005423 ! developing anatomical structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: composed_primarily_of UBERON:0003104 ! mesenchyme relationship: composed_primarily_of UBERON:0003104 ! mesenchyme [Term] id: UBERON:0017672 name: abdominal viscera namespace: uberon def: "A viscus that is part of a abdomen." [OBOL:automatic] subset: pheno_slim synonym: "abdominal viscera" EXACT [FMA:32413] synonym: "abdominal viscera set" EXACT [FMA:32413] synonym: "set of abdominal viscera" EXACT [FMA:32413] xref: FMA:32413 xref: FMA:67355 is_a: UBERON:0002075 ! viscus is_a: UBERON:0005172 ! abdomen element intersection_of: UBERON:0002075 ! viscus intersection_of: part_of UBERON:0000916 ! abdomen [Term] id: UBERON:0017748 name: lower primary incisor tooth namespace: uberon def: "A primary incisor tooth that is part of a lower jaw region." [OBOL:automatic] subset: pheno_slim synonym: "deciduous lower incisor tooth" RELATED [FMA:84215] synonym: "lower deciduous incisor tooth" EXACT [FMA:84215] synonym: "primary lower incisor tooth" EXACT [] xref: FMA:84215 xref: SCTID:420793009 is_a: UBERON:0003451 ! lower jaw incisor is_a: UBERON:0016476 ! primary incisor tooth is_a: UBERON:0018617 ! primary lower tooth intersection_of: UBERON:0016476 ! primary incisor tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0017750 name: proximal mesopodial endochondral element namespace: uberon def: "A mesopodial endochondral element that is in the most proximal part of the mesopodial skeleton, connected to the zeugopodial skeleton." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0015063 ! autopod endochondral element intersection_of: UBERON:0010363 ! endochondral element intersection_of: connected_to UBERON:0011584 ! zeugopodial skeleton intersection_of: part_of UBERON:0006716 ! mesopodium region relationship: connected_to UBERON:0011584 ! zeugopodial skeleton relationship: part_of UBERON:0009878 ! mesopodial skeleton property_value: editor_note "awaiting approval by phenoscape curators" xsd:string [Term] id: UBERON:0017751 name: proximal mesopodial cartilage element namespace: uberon def: "A proximal mesopodial endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015064 ! autopod cartilage is_a: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: UBERON:0017750 ! proximal mesopodial endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0018099 name: distal mesopodial endochondral element namespace: uberon def: "An endochondral element in the distal portion of the mesopodial skeleton, between the central mesopodial skeleton and the metapodial skeleton." [http://orcid.org/0000-0002-6601-2165] synonym: "distal mesopodial" EXACT SYSTEMATIC [UBERON:cjm] is_a: UBERON:0015063 ! autopod endochondral element relationship: part_of UBERON:0009878 ! mesopodial skeleton property_value: editor_note "TODO add logical definition" xsd:string [Term] id: UBERON:0018100 name: distal mesopodial cartilage element namespace: uberon def: "A distal mesopodial endochondral element that is composed primarily of cartilage tissue." [OBOL:automatic] is_a: UBERON:0015064 ! autopod cartilage is_a: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue relationship: develops_from UBERON:0018101 ! distal mesopodial pre-cartilage condensation [Term] id: UBERON:0018101 name: distal mesopodial pre-cartilage condensation namespace: uberon def: "A distal mesopodial endochondral element that is composed primarily of a pre-cartilage condensation." [OBOL:automatic] is_a: UBERON:0010882 ! limb bone pre-cartilage condensation is_a: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0018102 name: distal mesopodial bone namespace: uberon def: "A distal mesopodial endochondral element that is composed primarily of a bone tissue." [OBOL:automatic] is_a: UBERON:0003656 ! mesopodium bone is_a: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: UBERON:0018099 ! distal mesopodial endochondral element intersection_of: composed_primarily_of UBERON:0002481 ! bone tissue relationship: develops_from UBERON:0018100 ! distal mesopodial cartilage element [Term] id: UBERON:0018111 name: muscle layer of rectum namespace: uberon def: "A muscle layer that is part of the rectum." [http://orcid.org/0000-0002-6601-2165] synonym: "muscular coat of rectum" EXACT [FMA:15035] synonym: "muscularis externa of rectum" EXACT [FMA:15035] synonym: "rectal muscularis propria" EXACT [FMA:15035] synonym: "tunica muscularis (rectum)" EXACT [FMA:15035] synonym: "tunica muscularis recti" EXACT [FMA:TA] xref: FMA:15035 is_a: UBERON:0011198 ! muscle layer of large intestine intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0018112 name: rectum smooth muscle tissue namespace: uberon def: "Any portion of smooth muscle tissue that is part of the rectum." [http://orcid.org/0000-0002-6601-2165] synonym: "rectal smooth muscle tissue" EXACT [] synonym: "rectum smooth muscle" EXACT [] synonym: "smooth muscle of rectum" EXACT [] is_a: UBERON:0004220 ! large intestine smooth muscle is_a: UBERON:0004231 ! anal region smooth muscle is_a: UBERON:0016886 ! muscle tissue of terminal part of digestive tract intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001052 ! rectum relationship: part_of UBERON:0001052 ! rectum [Term] id: UBERON:0018113 name: left kidney interstitium namespace: uberon def: "A kidney interstitium that is part of a left kidney." [OBOL:automatic] synonym: "left renal stroma" EXACT [FMA:74271] synonym: "stroma of left kidney" EXACT [FMA:74271] xref: FMA:74271 is_a: UBERON:0005215 ! kidney interstitium intersection_of: UBERON:0005215 ! kidney interstitium intersection_of: part_of UBERON:0004538 ! left kidney relationship: part_of UBERON:0004538 ! left kidney [Term] id: UBERON:0018114 name: right kidney interstitium namespace: uberon def: "A kidney interstitium that is part of a right kidney." [OBOL:automatic] synonym: "right renal stroma" EXACT [FMA:74270] synonym: "stroma of right kidney" EXACT [FMA:74270] xref: FMA:74270 is_a: UBERON:0005215 ! kidney interstitium intersection_of: UBERON:0005215 ! kidney interstitium intersection_of: part_of UBERON:0004539 ! right kidney relationship: part_of UBERON:0004539 ! right kidney [Term] id: UBERON:0018115 name: left renal pelvis namespace: uberon def: "A renal pelvis that is part of a left ureter." [OBOL:automatic] synonym: "pelvis of left ureter" EXACT [FMA:15579] synonym: "renal pelvis of left kidney" EXACT [FMA:15579] xref: FMA:15579 xref: SCTID:243436005 is_a: UBERON:0001224 ! renal pelvis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001224 ! renal pelvis intersection_of: part_of UBERON:0001223 ! left ureter relationship: part_of UBERON:0001223 ! left ureter [Term] id: UBERON:0018116 name: right renal pelvis namespace: uberon def: "A renal pelvis that is part of a right ureter." [OBOL:automatic] synonym: "pelvis of right kidney" EXACT [FMA:15578] synonym: "pelvis of right ureter" EXACT [FMA:15578] xref: FMA:15578 xref: SCTID:243419002 is_a: UBERON:0001224 ! renal pelvis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0001224 ! renal pelvis intersection_of: part_of UBERON:0001222 ! right ureter relationship: part_of UBERON:0001222 ! right ureter [Term] id: UBERON:0018117 name: left renal cortex interstitium namespace: uberon def: "A renal cortex interstitium that is part of a left kidney." [OBOL:automatic] synonym: "cortical interstitial tissue of left kidney" EXACT [] is_a: UBERON:0005270 ! renal cortex interstitium is_a: UBERON:0018113 ! left kidney interstitium intersection_of: UBERON:0005270 ! renal cortex interstitium intersection_of: part_of UBERON:0004538 ! left kidney [Term] id: UBERON:0018118 name: right renal cortex interstitium namespace: uberon def: "A renal cortex interstitium that is part of a right kidney." [OBOL:automatic] synonym: "cortical interstitial tissue of right kidney" EXACT [] is_a: UBERON:0005270 ! renal cortex interstitium is_a: UBERON:0018114 ! right kidney interstitium intersection_of: UBERON:0005270 ! renal cortex interstitium intersection_of: part_of UBERON:0004539 ! right kidney [Term] id: UBERON:0018135 name: fibrocollagenous connective tissue namespace: uberon xref: FMA:83521 is_a: UBERON:0011824 ! fibrous connective tissue intersection_of: UBERON:0011824 ! fibrous connective tissue intersection_of: has_quality PATO:0002462 ! collagenous relationship: has_quality PATO:0002462 ! collagenous [Term] id: UBERON:0018142 name: caudal vertebra endochondral element namespace: uberon alt_id: UBERON:0015006 def: "Any vertebra endochondral element that is part of the caudal region of the vertebral column (tail or coccyx)." [http://orcid.org/0000-0002-6601-2165] synonym: "caudal vertebra element" EXACT [] synonym: "coccygeal vertebra element" NARROW [] synonym: "coccyx vertebra element" NARROW [] synonym: "tail vertebra element" EXACT [] is_a: UBERON:0005174 ! dorsal region element is_a: UBERON:0010913 ! vertebral element intersection_of: UBERON:0010913 ! vertebral element intersection_of: part_of UBERON:0006076 ! caudal region of vertebral column union_of: UBERON:0001095 ! caudal vertebra union_of: UBERON:0013503 ! caudal vertebra cartilage element union_of: UBERON:0013504 ! caudal vertebra pre-cartilage condensation relationship: part_of UBERON:0006076 ! caudal region of vertebral column [Term] id: UBERON:0018143 name: transverse process of cervical vertebra namespace: uberon def: "A transverse process that is part of a cervical vertebra." [http://orcid.org/0000-0002-6601-2165] xref: FMA:23894 xref: FMA:9913 xref: SCTID:280730000 is_a: UBERON:0001077 ! transverse process of vertebra intersection_of: UBERON:0001077 ! transverse process of vertebra intersection_of: part_of UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0002413 ! cervical vertebra property_value: UBPROP:0000008 "May be homologous with the cervical ribs of some vertebrates" xsd:string [Term] id: UBERON:0018144 name: cervical rib namespace: uberon def: "A rib that is attached to a cervical vertebra." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37825 {source="MA:th"} xref: MESH:D057070 xref: UBERONTEMP:d522e981-3a43-4cab-9862-4344b5c3ff22 is_a: UBERON:0002228 ! rib is_a: UBERON:0003458 ! neck bone intersection_of: UBERON:0002228 ! rib intersection_of: connected_to UBERON:0002413 ! cervical vertebra relationship: connected_to UBERON:0002413 ! cervical vertebra relationship: part_of UBERON:0005434 ! cervical region property_value: editor_note "Trunk, presacral and sacral ribs do not have a 'part of some region' asserted for them, we should add it to them[PHENOSCAPE:ad]" xsd:string property_value: RO:0002161 NCBITaxon:9606 {source="should be all Theria, see https://github.com/obophenotype/mouse-anatomy-ontology/issues/116"} property_value: UBPROP:0000008 "May be homologous with the transverse processes of cervical vertebra" xsd:string [Term] id: UBERON:0018145 name: lumbar rib namespace: uberon def: "A rib that is attached to a lumbar vertebra." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0002228 ! rib intersection_of: UBERON:0002228 ! rib intersection_of: connected_to UBERON:0002414 ! lumbar vertebra relationship: connected_to UBERON:0002414 ! lumbar vertebra relationship: part_of RO:0002577 ! system property_value: RO:0002161 NCBITaxon:32525 property_value: UBPROP:0000008 "May be homologous with the transverse processes of lumbar vertebra" xsd:string [Term] id: UBERON:0018146 name: transverse process of lumbar vertebra namespace: uberon def: "A transverse process that is part of a lumbar vertebra." [http://orcid.org/0000-0002-6601-2165] synonym: "costa lumbalis" EXACT LATIN [FMA:65469, FMA:TA] synonym: "lumbar transverse process" EXACT [FMA:16080] xref: FMA:16080 xref: FMA:65469 xref: SCTID:280733003 is_a: UBERON:0001077 ! transverse process of vertebra intersection_of: UBERON:0001077 ! transverse process of vertebra intersection_of: part_of UBERON:0002414 ! lumbar vertebra relationship: part_of UBERON:0002414 ! lumbar vertebra property_value: UBPROP:0000008 "May be homologous with the lumbar ribs of some vertebrates" xsd:string [Term] id: UBERON:0018150 name: skin of lower lip namespace: uberon def: "A zone of skin that is part of a lower lip." [OBOL:automatic] synonym: "lower lip skin" EXACT [FMA:24767] xref: FMA:24767 xref: SCTID:281630002 is_a: UBERON:0001458 ! skin of lip intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001835 ! lower lip relationship: part_of UBERON:0001835 ! lower lip [Term] id: UBERON:0018151 name: skin of upper lip namespace: uberon def: "A zone of skin that is part of a upper lip." [OBOL:automatic] synonym: "upper lip skin" EXACT [FMA:24765] xref: FMA:24765 xref: SCTID:281629007 is_a: UBERON:0001458 ! skin of lip is_a: UBERON:1000021 ! skin of face intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001834 ! upper lip relationship: part_of UBERON:0001834 ! upper lip [Term] id: UBERON:0018154 name: ligament of middle ear namespace: uberon def: "A ligament that is part of a middle ear." [OBOL:automatic] is_a: UBERON:0000211 ! ligament intersection_of: UBERON:0000211 ! ligament intersection_of: part_of UBERON:0001756 ! middle ear relationship: part_of UBERON:0001756 ! middle ear [Term] id: UBERON:0018234 name: stroma of pancreas namespace: uberon def: "A stroma that is part of a pancreas." [OBOL:automatic] subset: human_reference_atlas synonym: "pancreatic stroma" EXACT [FMA:63121] xref: FMA:63121 is_a: UBERON:0003891 ! stroma intersection_of: UBERON:0003891 ! stroma intersection_of: part_of UBERON:0001264 ! pancreas relationship: part_of UBERON:0001264 ! pancreas property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0018239 name: rhombomere boundary namespace: uberon def: "A boundary delimiting a rhombomere." [GO:0021654] synonym: "rhombomere junction" EXACT [] is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0001892 ! rhombomere relationship: connects UBERON:0001892 ! rhombomere relationship: part_of UBERON:0007277 ! presumptive hindbrain [Term] id: UBERON:0018251 name: meningeal vein namespace: uberon def: "One of the veins draining a meninix." [http://orcid.org/0000-0002-6601-2165] xref: FMA:50839 xref: SCTID:84842006 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002360 ! meninx relationship: drains UBERON:0002360 ! meninx relationship: part_of RO:0002577 ! system property_value: UBPROP:0000008 "In humans, any of several veins that accompany the meningeal arteries, communicate with the sinuses of the dura mater and diploic veins, and drain into the regional veins outside the cranial vault." xsd:string [Term] id: UBERON:0018252 name: internal pudendal vein namespace: uberon def: "Accompanying vein of internal pudendal artery." [Wikipedia:Internal_pudendal_veins] subset: human_reference_atlas synonym: "internal pudic vein" RELATED [Wikipedia:Internal_pudendal_veins] synonym: "vena pudenda interna" EXACT LATIN [Wikipedia:Internal_pudendal_veins] xref: FMA:18917 xref: SCTID:14885008 xref: Wikipedia:Internal_pudendal_veins is_a: UBERON:0009029 ! pudendal vein relationship: connected_to UBERON:0001317 ! internal iliac vein relationship: part_of RO:0002577 ! system property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000008 "In humans, they begin in the deep veins of the penis which issue from the corpus cavernosum penis, accompany the internal pudendal artery, and unite to form a single vessel, which ends in the internal iliac vein. They receive the veins from the urethral bulb, and the perineal and inferior hemorrhoidal veins" xsd:string [Term] id: UBERON:0018254 name: skeletal musculature namespace: uberon subset: grouping_class xref: EHDAA2:0001842 xref: EMAPA:35578 xref: MA:0000165 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000061 ! anatomical structure relationship: composed_primarily_of UBERON:0014892 ! skeletal muscle organ relationship: part_of UBERON:0000383 {source="MA"} ! musculature of body property_value: editor_note "Added for consistency with MA EMAPA and EHDAA2. See https://github.com/obophenotype/mouse-anatomy-ontology/issues/104" xsd:string [Term] id: UBERON:0018257 name: submucosa of digestive tract namespace: uberon def: "Any portion of submucosa that lines the digestive tract." [http://orcid.org/0000-0002-6601-2165] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000009 ! submucosa intersection_of: UBERON:0000009 ! submucosa intersection_of: part_of UBERON:0001555 ! digestive tract relationship: part_of UBERON:0001555 ! digestive tract [Term] id: UBERON:0018260 name: layer of muscle tissue namespace: uberon def: "Any organ component layer that consists of muscle tissue." [http://orcid.org/0000-0002-6601-2165] xref: FMA:45634 xref: NCIT:C75444 xref: UMLS:C0225358 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of UBERON:0002385 ! muscle tissue relationship: composed_primarily_of UBERON:0002385 ! muscle tissue property_value: UBPROP:0000012 "NCITA class may refer to smooth muscle only" xsd:string {external_ontology="NCIT"} [Term] id: UBERON:0018261 name: muscular coat of digestive tract namespace: uberon def: "A muscular coat that is part of a digestive tract." [OBOL:automatic] synonym: "muscular layer of digestive tract" RELATED [] synonym: "muscularis externa of digestive tract" RELATED [] synonym: "tunica externa of digestive tract" RELATED [] synonym: "tunica muscularis of digestive tract" EXACT [] is_a: UBERON:0006660 ! muscular coat intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001555 ! digestive tract relationship: capable_of_part_of GO:0030432 ! peristalsis relationship: part_of UBERON:0001555 ! digestive tract property_value: UBPROP:0000009 "responsible for gut movement, such as peristalsis" xsd:string [Term] id: UBERON:0018281 name: lower deciduous premolar 5 namespace: uberon def: "Fifth premolar (counting anteroposteriorly ) in the lower jaw." [PHENOSCAPE:alex] synonym: "dp5" RELATED ABBREVIATION [] xref: UBERONTEMP:ebd28885-699a-4637-9112-4ff68ddb6299 is_a: UBERON:0017272 ! lower primary premolar tooth is_a: UBERON:0018375 ! deciduous premolar 5 intersection_of: UBERON:0018375 ! deciduous premolar 5 intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018282 name: lower molar 3 namespace: uberon def: "Third molar (counting anteroposteriorly) in the lower jaw." [PHENOSCAPE:alex] synonym: "lower wisdom tooth" RELATED [] synonym: "wisdom tooth" RELATED [PHENOSCAPE:alex] xref: UBERONTEMP:d55a3eec-6055-46eb-84c5-0e03f25b0122 xref: Wikipedia:Wisdom_tooth is_a: UBERON:0003667 ! lower jaw molar is_a: UBERON:0018377 ! molar tooth 3 intersection_of: UBERON:0018377 ! molar tooth 3 intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018284 name: lower premolar 1 namespace: uberon def: "First premolar (counting anteroposteriorly ) in the lower jaw." [PHENOSCAPE:alex] xref: UBERONTEMP:31f522c3-c02f-42a7-b998-4881dffb8536 is_a: UBERON:0016943 ! lower premolar tooth is_a: UBERON:0018294 ! premolar 1 intersection_of: UBERON:0018294 ! premolar 1 intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018285 name: lower premolar 2 namespace: uberon def: "Second premolar (counting anteroposteriorly ) in the lower jaw." [PHENOSCAPE:alex] xref: UBERONTEMP:51fc0a23-6be1-4341-9048-34863ba2cadd is_a: UBERON:0016943 ! lower premolar tooth is_a: UBERON:0018640 ! premolar 2 intersection_of: UBERON:0018640 ! premolar 2 intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018294 name: premolar 1 namespace: uberon def: "First premolar (counting anteroposteriorly) in the jaw." [PHENOSCAPE:alex] synonym: "first premolar tooth" EXACT [] xref: SCTID:422368002 xref: UBERONTEMP:df0eb189-0c10-493d-b5ce-8fd091e09456 is_a: UBERON:0007120 ! premolar tooth [Term] id: UBERON:0018300 name: upper canine 1 namespace: uberon def: "First canine (counting anteroposteriorly) in the upper jaw." [PHENOSCAPE:Alex] synonym: "UC1" EXACT ABBREVIATION [] synonym: "upper canine UC1" EXACT [] xref: UBERONTEMP:14c28c28-237e-435d-9883-8dff529e64cc is_a: UBERON:0018621 ! upper canine tooth [Term] id: UBERON:0018301 name: upper deciduous premolar 5 namespace: uberon def: "Fifth premolar (counting anteroposteriorly ) in the upper jaw." [PHENOSCAPE:Alex] synonym: "dP5" RELATED ABBREVIATION [] xref: UBERONTEMP:ae0e62b6-59ad-4c21-8e15-b67570c5137a is_a: UBERON:0017271 ! upper primary premolar tooth is_a: UBERON:0018375 ! deciduous premolar 5 intersection_of: UBERON:0018375 ! deciduous premolar 5 intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018302 name: upper molar 1 namespace: uberon def: "First molar (counting anteroposteriorly) in the upper jaw." [PHENOSCAPE:Alex] xref: UBERONTEMP:12acbe6c-9036-48e3-b1a0-1f2fdaa0241d is_a: UBERON:0003666 ! upper jaw molar is_a: UBERON:0018376 ! molar tooth 1 intersection_of: UBERON:0018376 ! molar tooth 1 intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018321 name: foramen for glossopharyngeal nerve namespace: uberon def: "Foramen that allows the passge of the glossopharyngeal nerve (cranial nerve IX)." [PHENOSCAPE:alex] xref: UBERONTEMP:9ca0bda7-9111-4f59-bc72-5d47bc3d7d61 is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: conduit_for UBERON:0001649 ! glossopharyngeal nerve relationship: conduit_for UBERON:0001649 ! glossopharyngeal nerve relationship: part_of UBERON:0003128 ! cranium [Term] id: UBERON:0018326 name: ilioischiadic foramen namespace: uberon def: "Situated just caudal to the acetabulum, the foramen is bound dorsally by the illium and ventrally by the ischium. The foramen transmitts the ischiadic nerves and vessels (Baumel et al. 1993)." [PHENOSCAPE:alex] xref: UBERONTEMP:63e09c69-ac98-49ba-b232-2da5c7b19019 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005744 ! bone foramen intersection_of: UBERON:0005744 ! bone foramen intersection_of: conduit_for UBERON:0001322 ! sciatic nerve relationship: adjacent_to UBERON:0001273 ! ilium relationship: adjacent_to UBERON:0001274 ! ischium relationship: conduit_for UBERON:0001322 ! sciatic nerve relationship: part_of UBERON:0007832 ! pelvic girdle skeleton [Term] id: UBERON:0018375 name: deciduous premolar 5 namespace: uberon synonym: "deciduous premolar 5" EXACT [] synonym: "primary premolar 5 tooth" EXACT [] is_a: UBERON:0017269 ! primary premolar tooth is_a: UBERON:0018646 ! premolar tooth 5 intersection_of: UBERON:0018646 ! premolar tooth 5 intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0018376 name: molar tooth 1 namespace: uberon def: "The molar tooth of the upper or lower jaw that is phylogenetically number 1." [UBERON:cjm] synonym: "first molar tooth" EXACT [] synonym: "molar 1" EXACT [] synonym: "molar 1 tooth" EXACT [] xref: FMA:321614 xref: SCTID:422372003 is_a: UBERON:0003655 ! molar tooth [Term] id: UBERON:0018377 name: molar tooth 3 namespace: uberon def: "The molar tooth of the upper or lower jaw that is phylogenetically number 3." [UBERON:cjm] synonym: "molar 3" EXACT [] synonym: "molar 3 tooth" EXACT [] synonym: "third molar tooth" EXACT [] synonym: "wisdom tooth" RELATED HUMAN_PREFERRED [NCBITaxon:9606] xref: FMA:321612 xref: MESH:D008964 xref: NCIT:C60732 xref: SCTID:181222005 xref: Wikipedia:Wisdom_tooth is_a: UBERON:0003655 ! molar tooth property_value: UBPROP:0000008 "A wisdom tooth is in humans any of the usually four third molars, including mandibular third molar and maxillary third molar. Wisdom teeth usually appear between the ages of 17 and 25. Most adults have four wisdom teeth, but it is possible to have morebin which case they are called supernumerary teethbor fewerba condition called hypodontia. Wisdom teeth commonly affect other teeth as they develop, becoming impacted or 'coming in sideways'. They are often extracted when this occurs." xsd:string {source="Wikipedia:Wisdom_tooth"} [Term] id: UBERON:0018411 name: ligament of hip joint namespace: uberon def: "A skeletal ligament that is part of a hip joint." [OBOL:automatic] synonym: "hip joint ligament" EXACT [FMA:42868] xref: FMA:42868 xref: SCTID:182435001 is_a: UBERON:0005179 ! pelvic region element is_a: UBERON:0008846 ! skeletal ligament intersection_of: UBERON:0008846 ! skeletal ligament intersection_of: part_of UBERON:0001486 ! hip joint relationship: part_of UBERON:0001486 ! hip joint [Term] id: UBERON:0018413 name: facial nerve canal namespace: uberon def: "A Z-shaped canal running through the temporal bone from the internal acoustic meatus to the stylomastoid foramen. It is located within the middle ear region, according to its shape it is divided into three main segments: the labyrinthine, the tympanic, and the mastoidal segment ." [Wikipedia:Facial_canal] synonym: "canalis nervi facialis" EXACT LATIN [FMA:54952, FMA:TA] synonym: "facial canal" EXACT [FMA:54952] synonym: "fallopian canal" RELATED [FMA:54952] xref: FMA:54952 xref: Wikipedia:Facial_canal is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: conduit_for UBERON:0001647 ! facial nerve relationship: conduit_for UBERON:0001647 ! facial nerve relationship: part_of UBERON:0001678 ! temporal bone [Term] id: UBERON:0018415 name: ethmoid foramen namespace: uberon def: "An bone foramen in the ethmoid bone." [http://orcid.org/0000-0002-6601-2165] comment: Taxon nodes: In humans, refers to anterior or posterior ethmoid foramina synonym: "ethmoid foramina" RELATED PLURAL [] synonym: "ethmoidal foramen" EXACT [] synonym: "ethmoidal foramina" RELATED PLURAL [] synonym: "foramina ethmoidalia" EXACT LATIN [] xref: Wikipedia:Ethmoidal_foramina is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0004111 ! anatomical conduit intersection_of: part_of UBERON:0001679 ! ethmoid bone relationship: part_of UBERON:0001679 ! ethmoid bone property_value: UBPROP:0000008 "There are usually two Foramina ethmoidalia present on each side in the dog. Sometimes one is situated rostral to the other, but often it is dorsal. They are not homologous with the Foramen ethmoidale anterius and Foramen ethmoidale posterius of man. Therefore they are not listed separately.[NOMINA ANATOMICA VETERINARIA (2005)]" xsd:string [Term] id: UBERON:0018508 name: foramen of nasal bone namespace: uberon def: "A vascular foramen opening on the outer surface of a nasal bone." [http://medical-dictionary.thefreedictionary.com/nasal+foramina] synonym: "foramen of nasal bone" RELATED [] synonym: "foramina nasalia" EXACT LATIN [Wikipedia:Nasal_foramina] synonym: "nasal foramen" EXACT [] synonym: "nasal foramina" RELATED PLURAL [FMA:57653] xref: FMA:57653 xref: Wikipedia:Nasal_foramina is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0013685 ! foramen of skull intersection_of: UBERON:0013685 ! foramen of skull intersection_of: part_of UBERON:0001681 ! nasal bone relationship: conduit_for UBERON:0001981 ! blood vessel relationship: part_of UBERON:0001681 ! nasal bone [Term] id: UBERON:0018543 name: lumen of intestine namespace: uberon def: "The anatomical space within the intestine." [http://orcid.org/0000-0002-6601-2165] synonym: "gut lumen" RELATED [ZFA:0005807] synonym: "intestinal lumen" EXACT [FMA:14586] synonym: "intestine lumen" EXACT [ZFA:0005807] xref: FMA:14586 xref: TADS:0000495 xref: WBbt:0005791 xref: ZFA:0005807 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0000160 ! intestine relationship: luminal_space_of UBERON:0000160 ! intestine relationship: part_of UBERON:0000160 ! intestine property_value: editor_note "see notes in inclusivity in class 'intestine'" xsd:string [Term] id: UBERON:0018544 name: trigeminal nerve muscle namespace: uberon def: "Muscle innervated by the trigeminal nerve (Cranial Nerve V)." [MFMO:0000072] synonym: "muscle innervated by the trigeminal nerve" EXACT [] synonym: "muscles innervated by the trigeminal nerve" EXACT PLURAL [MFMO:0000072] xref: MFMO:0000072 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0001630 ! muscle organ intersection_of: UBERON:0001630 ! muscle organ intersection_of: innervated_by UBERON:0001645 ! trigeminal nerve relationship: develops_from UBERON:0004362 ! pharyngeal arch 1 relationship: innervated_by UBERON:0001645 ! trigeminal nerve [Term] id: UBERON:0018550 name: secondary incisor tooth namespace: uberon synonym: "permanent incisor" EXACT [] synonym: "permanent incisor tooth" EXACT [FMA:84201] xref: FMA:84201 xref: SCTID:304571003 is_a: UBERON:0001098 ! incisor tooth is_a: UBERON:0007775 ! secondary tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0018551 name: central incisor tooth namespace: uberon subset: pheno_slim synonym: "central incisor" EXACT [] xref: SCTID:422364000 is_a: UBERON:0001098 ! incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition relationship: in_central_side_of UBERON:0018645 ! incisor region of dentition relationship: part_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018552 name: lateral incisor tooth namespace: uberon subset: pheno_slim synonym: "lateral incisor" EXACT [] xref: SCTID:422366003 is_a: UBERON:0001098 ! incisor tooth is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition relationship: in_lateral_side_of UBERON:0018645 ! incisor region of dentition relationship: part_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018553 name: primary central incisor tooth namespace: uberon synonym: "primary central incisor" EXACT [] is_a: UBERON:0016476 ! primary incisor tooth is_a: UBERON:0018551 ! central incisor tooth intersection_of: UBERON:0016476 ! primary incisor tooth intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018554 name: primary lateral incisor tooth namespace: uberon synonym: "primary lateral incisor" EXACT [] is_a: UBERON:0016476 ! primary incisor tooth is_a: UBERON:0018552 ! lateral incisor tooth intersection_of: UBERON:0016476 ! primary incisor tooth intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018561 name: upper secondary canine tooth namespace: uberon def: "A secondary canine tooth that is part of a upper jaw region." [OBOL:automatic] synonym: "C" RELATED ABBREVIATION [] synonym: "maxillary secondary canine tooth" EXACT [FMA:55714] synonym: "permanent upper canine tooth" RELATED [FMA:55714] synonym: "upper permanent canine tooth" EXACT [FMA:55714] xref: FMA:55714 is_a: UBERON:0018584 ! secondary canine tooth is_a: UBERON:0018613 ! secondary upper tooth is_a: UBERON:0018621 ! upper canine tooth intersection_of: UBERON:0018584 ! secondary canine tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018562 name: lower secondary canine tooth namespace: uberon def: "A secondary canine tooth that is part of a lower jaw region." [OBOL:automatic] synonym: "c" RELATED ABBREVIATION [] synonym: "lower permanent canine tooth" EXACT [FMA:55715] synonym: "mandibular secondary canine tooth" EXACT [FMA:55715] synonym: "permanent lower canine tooth" RELATED [FMA:55715] xref: FMA:55715 is_a: UBERON:0018584 ! secondary canine tooth is_a: UBERON:0018614 ! permanent lower tooth is_a: UBERON:0018622 ! lower canine tooth intersection_of: UBERON:0018584 ! secondary canine tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018568 name: lower central secondary incisor tooth namespace: uberon def: "A lower jaw incisor that is in_the_central_side_of a dentition." [OBOL:automatic] subset: pheno_slim synonym: "i1" RELATED ABBREVIATION [] synonym: "lower central permanent incisor tooth" EXACT [FMA:55723] synonym: "mandibular central permanent incisor" EXACT [] synonym: "mandibular central secondary incisor tooth" EXACT [FMA:55723] xref: FMA:55723 is_a: UBERON:0018601 ! lower central incisor tooth is_a: UBERON:0018623 ! lower secondary incisor tooth intersection_of: UBERON:0003451 ! lower jaw incisor intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0018570 name: lower lateral secondary incisor tooth namespace: uberon def: "A lower jaw incisor that is in_the_lateral_side_of a dentition." [OBOL:automatic] subset: pheno_slim synonym: "i2" RELATED ABBREVIATION [] synonym: "lower lateral permanent incisor tooth" EXACT [FMA:55725] synonym: "mandibular lateral permanent incisor" EXACT [] synonym: "mandibular lateral secondary incisor tooth" EXACT [FMA:55725] xref: FMA:55725 is_a: UBERON:0018602 ! lower lateral incisor tooth is_a: UBERON:0018623 ! lower secondary incisor tooth intersection_of: UBERON:0003451 ! lower jaw incisor intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0018571 name: upper first secondary premolar tooth namespace: uberon synonym: "maxillary first secondary premolar tooth" EXACT [FMA:55801] synonym: "P1" RELATED ABBREVIATION [] synonym: "permanent first upper premolar tooth" RELATED [FMA:55801] synonym: "secondary first upper premolar tooth" RELATED [FMA:55801] synonym: "upper first permanent premolar tooth" EXACT [FMA:55801] xref: FMA:55801 is_a: UBERON:0016452 ! upper secondary premolar tooth is_a: UBERON:0018294 ! premolar 1 intersection_of: UBERON:0018294 ! premolar 1 intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018572 name: upper second secondary premolar tooth namespace: uberon synonym: "maxillary second secondary premolar tooth" EXACT [FMA:55802] synonym: "P2" RELATED ABBREVIATION [] synonym: "permanent second upper premolar tooth" RELATED [FMA:55802] synonym: "secondary second upper premolar tooth" RELATED [FMA:55802] synonym: "upper second permanent premolar tooth" EXACT [FMA:55802] xref: FMA:55802 is_a: UBERON:0016452 ! upper secondary premolar tooth is_a: UBERON:0018640 ! premolar 2 intersection_of: UBERON:0018640 ! premolar 2 intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018573 name: lower first secondary premolar tooth namespace: uberon synonym: "lower first permanent premolar tooth" EXACT [FMA:55803] synonym: "mandibular first secondary premolar tooth" EXACT [FMA:55803] synonym: "p1" RELATED ABBREVIATION [] synonym: "permanent first lower premolar tooth" RELATED [FMA:55803] synonym: "secondary first lower premolar tooth" RELATED [FMA:55803] xref: FMA:55803 is_a: UBERON:0016453 ! lower secondary premolar tooth is_a: UBERON:0018284 ! lower premolar 1 intersection_of: UBERON:0018294 ! premolar 1 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018574 name: lower second secondary premolar tooth namespace: uberon synonym: "lower second permanent premolar tooth" EXACT [FMA:55804] synonym: "mandibular second secondary premolar tooth" EXACT [FMA:55804] synonym: "p2" RELATED ABBREVIATION [] synonym: "permanent second lower premolar tooth" RELATED [FMA:55804] synonym: "secondary second lower premolar tooth" RELATED [FMA:55804] xref: FMA:55804 is_a: UBERON:0016453 ! lower secondary premolar tooth is_a: UBERON:0018285 ! lower premolar 2 intersection_of: UBERON:0018640 ! premolar 2 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018575 name: upper first secondary molar tooth namespace: uberon synonym: "M1" RELATED ABBREVIATION [] synonym: "maxillary first secondary molar tooth" EXACT [FMA:55811] synonym: "upper first permanent molar tooth" EXACT [FMA:55811] xref: FMA:55811 is_a: UBERON:0013619 ! upper secondary molar tooth is_a: UBERON:0018302 ! upper molar 1 is_a: UBERON:0018608 ! permanent molar tooth 1 intersection_of: UBERON:0018376 ! molar tooth 1 intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018576 name: upper second secondary molar tooth namespace: uberon synonym: "M2" RELATED ABBREVIATION [] synonym: "maxillary second secondary molar tooth" EXACT [FMA:55812] synonym: "upper second permanent tooth" EXACT [FMA:55812] xref: FMA:55812 is_a: UBERON:0013619 ! upper secondary molar tooth is_a: UBERON:0018607 ! permanent molar tooth 2 intersection_of: UBERON:0018606 ! molar tooth 2 intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018577 name: upper third secondary molar tooth namespace: uberon synonym: "dens serotinus (upper)" EXACT LATIN [FMA:55813, FMA:TA] synonym: "M3" RELATED ABBREVIATION [] synonym: "maxillary third secondary molar tooth" EXACT [FMA:55813] synonym: "permanent third upper molar tooth" RELATED [FMA:55813] synonym: "secondary third upper molar tooth" RELATED [FMA:55813] synonym: "upper third permanent molar tooth" EXACT [FMA:55813] synonym: "upper wisdom tooth" EXACT [FMA:55813] xref: FMA:55813 is_a: UBERON:0013619 ! upper secondary molar tooth is_a: UBERON:0018377 ! molar tooth 3 intersection_of: UBERON:0018377 ! molar tooth 3 intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018578 name: lower first secondary molar tooth namespace: uberon synonym: "lower first permanent molar tooth" EXACT [FMA:55814] synonym: "m1" RELATED ABBREVIATION [] synonym: "mandibular first secondary molar tooth" EXACT [FMA:55814] xref: FMA:55814 is_a: UBERON:0013621 ! lower secondary molar tooth is_a: UBERON:0018608 ! permanent molar tooth 1 intersection_of: UBERON:0018376 ! molar tooth 1 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018579 name: lower second secondary molar tooth namespace: uberon synonym: "lower second permanent molar tooth" EXACT [FMA:55815] synonym: "lower secondary molar 2" EXACT [] synonym: "m2" RELATED ABBREVIATION [] synonym: "mandibular second secondary molar tooth" EXACT [FMA:55815] xref: FMA:55815 is_a: UBERON:0013621 ! lower secondary molar tooth is_a: UBERON:0018607 ! permanent molar tooth 2 intersection_of: UBERON:0018606 ! molar tooth 2 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018580 name: lower third secondary molar tooth namespace: uberon synonym: "lower secondary molar 3" EXACT [] synonym: "lower third permanent molar tooth" EXACT [FMA:55817] synonym: "lower wisdom tooth" EXACT [FMA:55817] synonym: "m3" RELATED ABBREVIATION [] synonym: "mandibular third secondary molar tooth" EXACT [FMA:55817] synonym: "secondary third lower molar tooth" RELATED [FMA:55817] xref: FMA:55817 is_a: UBERON:0013621 ! lower secondary molar tooth is_a: UBERON:0018282 ! lower molar 3 intersection_of: UBERON:0018377 ! molar tooth 3 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018583 name: primary canine tooth namespace: uberon synonym: "deciduous canine tooth" EXACT [FMA:84202] synonym: "primary tooth C" EXACT [FMA:84202] synonym: "temporary canine tooth" EXACT [FMA:84202] xref: FMA:84202 xref: SCTID:15819002 is_a: UBERON:0003674 ! cuspid is_a: UBERON:0007115 ! deciduous tooth intersection_of: UBERON:0003674 ! cuspid intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0018584 name: secondary canine tooth namespace: uberon synonym: "permanent canine tooth" EXACT [FMA:84203] xref: FMA:84203 xref: SCTID:134340007 is_a: UBERON:0003674 ! cuspid is_a: UBERON:0007775 ! secondary tooth intersection_of: UBERON:0003674 ! cuspid intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0018588 name: upper first primary molar tooth namespace: uberon synonym: "dM1" RELATED ABBREVIATION [] synonym: "upper first deciduous molar tooth" EXACT [FMA:84211] synonym: "upper primary tooth D" EXACT [FMA:84211] xref: FMA:84211 is_a: UBERON:0013617 ! upper primary molar tooth is_a: UBERON:0018302 ! upper molar 1 is_a: UBERON:0018644 ! deciduous molar tooth 1 intersection_of: UBERON:0018376 ! molar tooth 1 intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007116 ! primary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018589 name: lower first primary molar tooth namespace: uberon synonym: "dm1" RELATED ABBREVIATION [] synonym: "lower first deciduous molar tooth" EXACT [FMA:84212] synonym: "lower primary molar 1" EXACT [] synonym: "lower primary tooth D" EXACT [FMA:84212] xref: FMA:84212 is_a: UBERON:0013620 ! lower primary molar tooth is_a: UBERON:0018644 ! deciduous molar tooth 1 intersection_of: UBERON:0018376 ! molar tooth 1 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007116 ! primary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018591 name: upper primary incisor tooth namespace: uberon def: "A primary incisor tooth that is part of a upper jaw region." [OBOL:automatic] synonym: "deciduous upper incisor tooth" RELATED [FMA:84214] synonym: "upper deciduous incisor tooth" EXACT [FMA:84214] xref: FMA:84214 is_a: UBERON:0003450 ! upper jaw incisor is_a: UBERON:0016476 ! primary incisor tooth is_a: UBERON:0018616 ! primary upper tooth intersection_of: UBERON:0016476 ! primary incisor tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018593 name: upper central primary incisor tooth namespace: uberon def: "A upper primary canine tooth that is in_the_central_side_of a dentition." [OBOL:automatic] subset: pheno_slim synonym: "dI1" RELATED ABBREVIATION [] synonym: "upper central deciduous incisor tooth" EXACT [FMA:84216] synonym: "upper primary tooth A" EXACT [FMA:84216] xref: FMA:84216 is_a: UBERON:0018553 ! primary central incisor tooth is_a: UBERON:0018591 ! upper primary incisor tooth is_a: UBERON:0018603 ! upper central incisor tooth intersection_of: UBERON:0018591 ! upper primary incisor tooth intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018594 name: upper lateral primary incisor tooth namespace: uberon def: "A upper primary canine tooth that is in_the_lateral_side_of a dentition." [OBOL:automatic] subset: pheno_slim synonym: "dI2" RELATED ABBREVIATION [] synonym: "upper lateral deciduous incisor tooth" EXACT [FMA:84217] synonym: "upper primary tooth B" EXACT [FMA:84217] xref: FMA:84217 is_a: UBERON:0018554 ! primary lateral incisor tooth is_a: UBERON:0018591 ! upper primary incisor tooth is_a: UBERON:0018604 ! upper lateral incisor tooth intersection_of: UBERON:0018591 ! upper primary incisor tooth intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018595 name: lower central primary incisor tooth namespace: uberon def: "A lower primary incisor tooth that is in_the_central_side_of a dentition." [OBOL:automatic] subset: pheno_slim synonym: "deciduous lower central incisor tooth" RELATED [FMA:84218] synonym: "di1" RELATED ABBREVIATION [] synonym: "lower central deciduous incisor tooth" EXACT [FMA:84218] synonym: "lower primary tooth A" EXACT [FMA:84218] xref: FMA:84218 is_a: UBERON:0017748 ! lower primary incisor tooth is_a: UBERON:0018553 ! primary central incisor tooth is_a: UBERON:0018601 ! lower central incisor tooth intersection_of: UBERON:0017748 ! lower primary incisor tooth intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018596 name: lower lateral primary incisor tooth namespace: uberon def: "A lower primary incisor tooth that is in_the_lateral_side_of a dentition." [OBOL:automatic] subset: pheno_slim synonym: "deciduous lower lateral incisor tooth" RELATED [FMA:84219] synonym: "di2" RELATED ABBREVIATION [] synonym: "lower lateral deciduous incisor tooth" EXACT [FMA:84219] synonym: "lower primary tooth B" EXACT [FMA:84219] synonym: "mandibular lateral primary incisor" EXACT [] xref: FMA:84219 is_a: UBERON:0017748 ! lower primary incisor tooth is_a: UBERON:0018554 ! primary lateral incisor tooth is_a: UBERON:0018602 ! lower lateral incisor tooth intersection_of: UBERON:0017748 ! lower primary incisor tooth intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition [Term] id: UBERON:0018597 name: upper primary canine tooth namespace: uberon def: "A primary canine tooth that is part of a upper jaw region." [OBOL:automatic] synonym: "dC" RELATED ABBREVIATION [] synonym: "deciduous upper canine tooth" RELATED [FMA:84228] synonym: "upper deciduous canine tooth" EXACT [FMA:84228] synonym: "upper primary tooth C" EXACT [FMA:84228] xref: FMA:84228 xref: SCTID:421810006 is_a: UBERON:0018583 ! primary canine tooth is_a: UBERON:0018616 ! primary upper tooth is_a: UBERON:0018621 ! upper canine tooth intersection_of: UBERON:0018583 ! primary canine tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018598 name: lower primary canine tooth namespace: uberon def: "A primary canine tooth that is part of a lower jaw region." [OBOL:automatic] synonym: "dc" RELATED ABBREVIATION [] synonym: "deciduous lower canine tooth" RELATED [FMA:84229] synonym: "lower deciduous canine tooth" EXACT [FMA:84229] synonym: "lower primary tooth C" EXACT [FMA:84229] synonym: "primary lower canine tooth" EXACT [] xref: FMA:84229 xref: SCTID:420326009 is_a: UBERON:0018583 ! primary canine tooth is_a: UBERON:0018617 ! primary lower tooth is_a: UBERON:0018622 ! lower canine tooth intersection_of: UBERON:0018583 ! primary canine tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018599 name: upper second primary molar tooth namespace: uberon synonym: "dM2" RELATED ABBREVIATION [] synonym: "upper primary tooth E" EXACT [FMA:84236] synonym: "upper second deciduous molar tooth" EXACT [FMA:84236] xref: FMA:84236 is_a: UBERON:0013617 ! upper primary molar tooth is_a: UBERON:0018643 ! deciduous molar tooth 2 intersection_of: UBERON:0018606 ! molar tooth 2 intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007116 ! primary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018600 name: lower second primary molar tooth namespace: uberon synonym: "dm2" RELATED ABBREVIATION [] synonym: "lower primary tooth E" EXACT [FMA:84237] synonym: "lower second deciduous molar tooth" EXACT [FMA:84237] xref: FMA:84237 is_a: UBERON:0013620 ! lower primary molar tooth is_a: UBERON:0018643 ! deciduous molar tooth 2 intersection_of: UBERON:0018606 ! molar tooth 2 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007116 ! primary dentition property_value: editor_note "TODO - tooth numbering nomeculature to be aligned across species" xsd:string [Term] id: UBERON:0018601 name: lower central incisor tooth namespace: uberon def: "An incisor tooth that is in_the_central_side_of a dentition and is part of a lower jaw region." [OBOL:automatic] subset: pheno_slim synonym: "lower central incisor" EXACT [] synonym: "mandibular central incisor" EXACT [] xref: FMA:290182 is_a: UBERON:0003451 ! lower jaw incisor is_a: UBERON:0018551 ! central incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018602 name: lower lateral incisor tooth namespace: uberon def: "An incisor tooth that is in_the_lateral_side_of a dentition and is part of a lower jaw region." [OBOL:automatic] subset: pheno_slim synonym: "lower lateral incisor" EXACT [] synonym: "mandibular lateral incisor" EXACT [] xref: FMA:290197 is_a: UBERON:0003451 ! lower jaw incisor is_a: UBERON:0018552 ! lateral incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018603 name: upper central incisor tooth namespace: uberon def: "An incisor tooth that is in_the_central_side_of a dentition and is part of a upper jaw region." [OBOL:automatic] subset: pheno_slim synonym: "maxillary central incisor" EXACT [] synonym: "upper central incisor" EXACT [] xref: FMA:290180 is_a: UBERON:0003450 ! upper jaw incisor is_a: UBERON:0018551 ! central incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_central_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018604 name: upper lateral incisor tooth namespace: uberon def: "An incisor tooth that is in_the_lateral_side_of a dentition and is part of a upper jaw region." [OBOL:automatic] subset: pheno_slim synonym: "maxillary lateral incisor" EXACT [] synonym: "upper lateral incisor" EXACT [] xref: FMA:290194 is_a: UBERON:0003450 ! upper jaw incisor is_a: UBERON:0018552 ! lateral incisor tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: in_lateral_side_of UBERON:0018645 ! incisor region of dentition intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018606 name: molar tooth 2 namespace: uberon def: "The molar tooth of the upper or lower jaw that is phylogenetically number 2." [UBERON:cjm] synonym: "molar 2" EXACT [] synonym: "molar 2 tooth" EXACT [] synonym: "second molar tooth" EXACT [] xref: FMA:321613 xref: SCTID:422374002 is_a: UBERON:0003655 ! molar tooth [Term] id: UBERON:0018607 name: permanent molar tooth 2 namespace: uberon subset: pheno_slim synonym: "permanent second molar tooth" EXACT [] synonym: "second permanent molar" EXACT [] synonym: "second permanent molar tooth" EXACT [] synonym: "secondary second molar tooth" EXACT [] xref: SCTID:420479003 is_a: UBERON:0013618 ! secondary molar tooth is_a: UBERON:0018606 ! molar tooth 2 intersection_of: UBERON:0018606 ! molar tooth 2 intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0018608 name: permanent molar tooth 1 namespace: uberon subset: pheno_slim synonym: "first permanent molar" EXACT [] synonym: "first permanent molar tooth" EXACT [] synonym: "permanent first molar tooth" EXACT [] xref: SCTID:304565009 is_a: UBERON:0013618 ! secondary molar tooth is_a: UBERON:0018376 ! molar tooth 1 intersection_of: UBERON:0018376 ! molar tooth 1 intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0018613 name: secondary upper tooth namespace: uberon synonym: "permanent upper tooth" EXACT [] xref: SCTID:245564000 is_a: UBERON:0003267 ! tooth of upper jaw is_a: UBERON:0007775 ! secondary tooth intersection_of: UBERON:0007775 ! secondary tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018614 name: permanent lower tooth namespace: uberon synonym: "secondary lower tooth" EXACT [] xref: SCTID:245588003 is_a: UBERON:0003268 ! tooth of lower jaw is_a: UBERON:0007775 ! secondary tooth intersection_of: UBERON:0007775 ! secondary tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018616 name: primary upper tooth namespace: uberon synonym: "deciduous upper tooth" EXACT [] xref: SCTID:245613009 is_a: UBERON:0003267 ! tooth of upper jaw is_a: UBERON:0007115 ! deciduous tooth intersection_of: UBERON:0007115 ! deciduous tooth intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018617 name: primary lower tooth namespace: uberon synonym: "deciduous lower tooth" EXACT [] xref: SCTID:245628009 is_a: UBERON:0003268 ! tooth of lower jaw is_a: UBERON:0007115 ! deciduous tooth intersection_of: UBERON:0007115 ! deciduous tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018621 name: upper canine tooth namespace: uberon synonym: "maxillary canine tooth" EXACT [] synonym: "upper canine" EXACT [] synonym: "upper cuspid" EXACT [] is_a: UBERON:0003267 ! tooth of upper jaw is_a: UBERON:0003674 ! cuspid intersection_of: UBERON:0003674 ! cuspid intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018622 name: lower canine tooth namespace: uberon synonym: "lower canine" EXACT [] synonym: "lower cuspid" EXACT [] synonym: "mandibular canine tooth" EXACT [] is_a: UBERON:0003268 ! tooth of lower jaw is_a: UBERON:0003674 ! cuspid intersection_of: UBERON:0003674 ! cuspid intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018623 name: lower secondary incisor tooth namespace: uberon synonym: "lower permanent incisor tooth" EXACT [FMA:55713] synonym: "mandibular secondary incisor tooth" EXACT [FMA:55713] synonym: "permanent lower incisor tooth" RELATED [FMA:55713] xref: FMA:55713 is_a: UBERON:0003451 ! lower jaw incisor is_a: UBERON:0018550 ! secondary incisor tooth is_a: UBERON:0018614 ! permanent lower tooth intersection_of: UBERON:0018550 ! secondary incisor tooth intersection_of: part_of UBERON:0001710 ! lower jaw region [Term] id: UBERON:0018640 name: premolar 2 namespace: uberon synonym: "second premolar tooth" EXACT [] xref: SCTID:422370006 is_a: UBERON:0007120 ! premolar tooth [Term] id: UBERON:0018643 name: deciduous molar tooth 2 namespace: uberon synonym: "deciduous second molar tooth" EXACT [] xref: SCTID:422595006 is_a: UBERON:0013616 ! primary molar tooth is_a: UBERON:0018606 ! molar tooth 2 intersection_of: UBERON:0018606 ! molar tooth 2 intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0018644 name: deciduous molar tooth 1 namespace: uberon synonym: "deciduous first molar tooth" EXACT [] synonym: "deciduous molar 1" EXACT [] synonym: "first temporarary molar" EXACT [] xref: SCTID:423890001 is_a: UBERON:0013616 ! primary molar tooth is_a: UBERON:0018376 ! molar tooth 1 intersection_of: UBERON:0018376 ! molar tooth 1 intersection_of: part_of UBERON:0007116 ! primary dentition [Term] id: UBERON:0018645 name: incisor region of dentition namespace: uberon def: "The subdivision of the dentition that consists entire of incisor teeth." [http://orcid.org/0000-0002-6601-2165] synonym: "set of incisors" RELATED [] is_a: UBERON:0010314 ! structure with developmental contribution from neural crest intersection_of: UBERON:0000061 ! anatomical structure intersection_of: composed_primarily_of UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0003672 ! dentition relationship: composed_primarily_of UBERON:0001098 ! incisor tooth relationship: part_of UBERON:0003672 ! dentition [Term] id: UBERON:0018646 name: premolar tooth 5 namespace: uberon def: "The premolar tooth of the upper or lower jaw that is phylogenetically number 5." [UBERON:cjm] synonym: "premolar 5" EXACT [] is_a: UBERON:0007120 ! premolar tooth [Term] id: UBERON:0018647 name: premolar tooth 4 namespace: uberon def: "The premolar tooth of the upper or lower jaw that is phylogenetically number 4." [UBERON:cjm] synonym: "premolar 4" EXACT [] is_a: UBERON:0007120 ! premolar tooth [Term] id: UBERON:0018648 name: upper premolar 4 namespace: uberon comment: Often called the carnassial tooth, this tooth acts with its counterpart in the lower jaw (the 1st molar in that case) to slice food in a scissoring action.[MURDOCH:2142] synonym: "carnassial tooth" RELATED [MURDOCH:2142] is_a: UBERON:0016944 ! upper premolar tooth is_a: UBERON:0018647 ! premolar tooth 4 intersection_of: UBERON:0018647 ! premolar tooth 4 intersection_of: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0018649 name: cardiac muscle tissue of ventricle namespace: uberon synonym: "ventricular cardiac muscle tissue" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ventricular heart muscle" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "ventricular muscle" RELATED [http://orcid.org/0000-0002-6601-2165] xref: FMA:83450 is_a: UBERON:0004493 ! cardiac muscle tissue of myocardium intersection_of: UBERON:0001133 ! cardiac muscle tissue intersection_of: part_of UBERON:0002082 ! cardiac ventricle relationship: part_of UBERON:0001083 ! myocardium of ventricle [Term] id: UBERON:0018664 name: neck of bone element namespace: uberon def: "The neck region of a bone organ." [http://orcid.org/0000-0002-6601-2165] synonym: "bone neck" EXACT [] synonym: "neck of bone" EXACT [] is_a: UBERON:0001560 ! neck of organ is_a: UBERON:0005913 {notes="https://github.com/obophenotype/uberon/wiki/Hidden-GCIs"} ! zone of bone organ intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0001474 ! bone element [Term] id: UBERON:0018667 name: neck of scapula namespace: uberon synonym: "anatomical neck of scapula" EXACT [FMA:23254] synonym: "collum scapulae" EXACT [] synonym: "scapular neck" EXACT [FMA:23254] xref: FMA:23254 xref: SCTID:181915009 is_a: UBERON:0018664 ! neck of bone element intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0006849 ! scapula relationship: part_of UBERON:0006849 ! scapula [Term] id: UBERON:0018673 name: neck of fibula namespace: uberon subset: human_reference_atlas synonym: "fibula neck" EXACT [FMA:35508] synonym: "fibular neck" EXACT [] xref: EMAPA:37891 {source="MA:th"} xref: FMA:35508 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0018664 ! neck of bone element intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0001446 ! fibula relationship: part_of UBERON:0001446 ! fibula property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0018674 name: heart vasculature namespace: uberon def: "An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart." [ZFA:0005811, ZFA:CVS] synonym: "cardiac vasculature" EXACT [FMA:73747] xref: FMA:73747 xref: ZFA:0005811 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0000948 ! heart relationship: part_of UBERON:0000948 ! heart [Term] id: UBERON:0018692 name: dorsal side of post-anal tail namespace: uberon is_a: UBERON:0034929 ! external soft tissue zone intersection_of: UBERON:0034929 ! external soft tissue zone intersection_of: in_dorsal_side_of UBERON:0007812 ! post-anal tail relationship: in_dorsal_side_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0001137 ! dorsum relationship: part_of UBERON:0007812 ! post-anal tail [Term] id: UBERON:0018707 name: bladder organ namespace: uberon def: "A membranous sac in animals that serves as the receptacle of a liquid or contains gas." [BTO:0000123] synonym: "bladder" NARROW [BTO:0000123] xref: BTO:0000123 is_a: UBERON:0000489 ! cavitated compound organ is_a: UBERON:0009856 ! sac relationship: has_quality PATO:0002468 ! distensible relationship: location_of UBERON:0000463 ! organism substance [Term] id: UBERON:0019042 name: reproductive system mucosa namespace: uberon synonym: "genital mucosa" EXACT [BTO:0002439] xref: BTO:0002439 is_a: UBERON:0000344 ! mucosa is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0000990 ! reproductive system [Term] id: UBERON:0019143 name: intramuscular adipose tissue namespace: uberon def: "Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes." [BTO:0004043] synonym: "intramuscular fat" RELATED [BTO:0004043] xref: BTO:0004043 is_a: UBERON:0001013 ! adipose tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: part_of UBERON:0014892 ! skeletal muscle organ relationship: part_of UBERON:0014892 ! skeletal muscle organ [Term] id: UBERON:0019189 name: carotid artery endothelium namespace: uberon synonym: "carotid endothelium" RELATED [BTO:0004626] synonym: "carotid epithelium" RELATED [] xref: BTO:0004626 is_a: UBERON:0001917 ! endothelium of artery intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0005396 ! carotid artery segment relationship: part_of UBERON:0005396 ! carotid artery segment [Term] id: UBERON:0019190 name: mucous gland of lung namespace: uberon synonym: "bronchial gland" EXACT [FMA:13119] synonym: "bronchial mucous gland" EXACT [FMA:13119] synonym: "peribronchial gland" EXACT [BTO:0004638] xref: BTO:0004638 xref: FMA:13119 xref: SCTID:88410004 is_a: UBERON:0000414 ! mucous gland is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0000414 ! mucous gland intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung [Term] id: UBERON:0019196 name: iliac artery endothelium namespace: uberon xref: BTO:0004661 is_a: UBERON:0001917 ! endothelium of artery intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0005609 ! iliac artery relationship: part_of UBERON:0005609 ! iliac artery [Term] id: UBERON:0019204 name: skin epithelium namespace: uberon def: "Any region of epithelium that is part of a skin region." [http://orcid.org/0000-0002-6601-2165] xref: BTO:0004382 is_a: UBERON:0010371 ! ecto-epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000014 ! zone of skin relationship: part_of UBERON:0000014 ! zone of skin [Term] id: UBERON:0019206 name: tongue papilla epithelium namespace: uberon xref: EMAPA:35869 xref: MA:0003178 is_a: UBERON:0002424 ! oral epithelium is_a: UBERON:0003357 ! epithelium of tongue intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0001726 ! papilla of tongue relationship: part_of UBERON:0001726 ! papilla of tongue [Term] id: UBERON:0019207 name: chorioretinal region namespace: uberon def: "The part of the eye that consists of both the retina and the optic choroid." [http://orcid.org/0000-0002-6601-2165, UBERON:drseb] subset: pheno_slim synonym: "chorioretina" EXACT [] synonym: "choroid and retina" EXACT [] synonym: "retinachoroid" EXACT [] synonym: "retinachoroidal region" EXACT [] xref: SCTID:110701000 is_a: UBERON:0000481 ! multi-tissue structure is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0010314 ! structure with developmental contribution from neural crest relationship: has_part UBERON:0000966 ! retina relationship: has_part UBERON:0001776 ! optic choroid relationship: part_of NCBITaxon:6072 ! Eumetazoa relationship: part_of UBERON:0010230 ! eyeball of camera-type eye [Term] id: UBERON:0019221 name: digit 1 or 5 namespace: uberon def: "Either of the outermost digits in a five-digit autopod, or their phylogenetic equivalent." [UBERON:cjm] synonym: "lateral digit" RELATED HUMAN_PREFERRED [] synonym: "outer digit" RELATED HUMAN_PREFERRED [] synonym: "outermost digit" RELATED HUMAN_PREFERRED [] is_a: UBERON:0002544 ! digit union_of: UBERON:0006048 ! digit 1 union_of: UBERON:0006052 ! digit 5 relationship: in_lateral_side_of UBERON:0002470 {gci_relation="part_of", gci_filler="NCBITaxon:9606"} ! autopod region property_value: seeAlso "https://github.com/obophenotype/uberon/issues/592" xsd:anyURI [Term] id: UBERON:0019222 name: digit 2, 3 or 4 namespace: uberon def: "Any of the three medial digits in a five-digit autopod, or their phylogenetic equivalent." [UBERON:cjm] subset: pheno_slim synonym: "medial digit" RELATED HUMAN_PREFERRED [] synonym: "mesoaxial digit" RELATED HUMAN_PREFERRED [] is_a: UBERON:0002544 ! digit union_of: UBERON:0006049 ! digit 2 union_of: UBERON:0006050 ! digit 3 union_of: UBERON:0006051 ! digit 4 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/592" xsd:anyURI [Term] id: UBERON:0019231 name: manual digit 1 or 5 namespace: uberon synonym: "lateral finger" RELATED HUMAN_PREFERRED [] synonym: "lateral manual digit" RELATED HUMAN_PREFERRED [] synonym: "outer manual digit" RELATED HUMAN_PREFERRED [] synonym: "outermost manual digit" RELATED HUMAN_PREFERRED [] is_a: UBERON:0002389 ! manual digit is_a: UBERON:0019221 ! digit 1 or 5 union_of: UBERON:0001463 ! manual digit 1 union_of: UBERON:0003625 ! manual digit 5 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/592" xsd:anyURI [Term] id: UBERON:0019232 name: manual digit 2, 3 or 4 namespace: uberon subset: pheno_slim synonym: "medial manual digit" RELATED HUMAN_PREFERRED [] synonym: "mesoaxial manual digit" RELATED HUMAN_PREFERRED [] synonym: "mesoxaxial finger" RELATED HUMAN_PREFERRED [] is_a: UBERON:0002389 ! manual digit is_a: UBERON:0019222 ! digit 2, 3 or 4 union_of: UBERON:0003622 ! manual digit 2 union_of: UBERON:0003623 ! manual digit 3 union_of: UBERON:0003624 ! manual digit 4 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/592" xsd:anyURI [Term] id: UBERON:0019241 name: pedal digit 1 or 5 namespace: uberon synonym: "lateral pedal digit" RELATED HUMAN_PREFERRED [] synonym: "lateral toe" RELATED HUMAN_PREFERRED [] synonym: "outer pedal digit" RELATED HUMAN_PREFERRED [] synonym: "outermost pedal digit" RELATED HUMAN_PREFERRED [] is_a: UBERON:0001466 ! pedal digit is_a: UBERON:0019221 ! digit 1 or 5 union_of: UBERON:0003631 ! pedal digit 1 union_of: UBERON:0003635 ! pedal digit 5 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/592" xsd:anyURI [Term] id: UBERON:0019242 name: pedal digit 2, 3 or 4 namespace: uberon subset: pheno_slim synonym: "medial pedal digit" RELATED HUMAN_PREFERRED [] synonym: "mesoaxial pedal digit" RELATED HUMAN_PREFERRED [] synonym: "mesoxaxial ftoe" RELATED HUMAN_PREFERRED [] is_a: UBERON:0001466 ! pedal digit is_a: UBERON:0019222 ! digit 2, 3 or 4 union_of: UBERON:0003632 ! pedal digit 2 union_of: UBERON:0003633 ! pedal digit 3 union_of: UBERON:0003634 ! pedal digit 4 property_value: seeAlso "https://github.com/obophenotype/uberon/issues/592" xsd:anyURI [Term] id: UBERON:0019253 name: upper secondary incisor tooth namespace: uberon synonym: "maxillary secondary incisor tooth" EXACT [FMA:55712] synonym: "upper permanent incisor" EXACT [] synonym: "upper permanent incisor tooth" EXACT [FMA:55712] xref: FMA:55712 is_a: UBERON:0003450 ! upper jaw incisor is_a: UBERON:0018550 ! secondary incisor tooth is_a: UBERON:0018613 ! secondary upper tooth intersection_of: UBERON:0001098 ! incisor tooth intersection_of: part_of UBERON:0001709 ! upper jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition [Term] id: UBERON:0019258 name: white matter of hindbrain namespace: uberon def: "A white matter that is part of the hindbrain." [OBOL:automatic] subset: human_reference_atlas xref: DHBA:10668 xref: FMA:268636 is_a: UBERON:0003544 ! brain white matter intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002028 ! hindbrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0019261 name: white matter of forebrain namespace: uberon def: "A white matter that is part of the forebrain." [OBOL:automatic] subset: human_reference_atlas xref: DHBA:10557 xref: FMA:268634 is_a: UBERON:0003544 ! brain white matter intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001890 ! forebrain relationship: part_of UBERON:0001890 ! forebrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0019262 name: white matter of myelencephalon namespace: uberon def: "A white matter that is part of the myelencephalon." [OBOL:automatic] synonym: "myelencephalic white matter" EXACT [HBA:MYWM] xref: HBA:9298 is_a: UBERON:0019258 ! white matter of hindbrain intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0005290 ! myelencephalon relationship: part_of UBERON:0005290 ! myelencephalon [Term] id: UBERON:0019263 name: gray matter of hindbrain namespace: uberon subset: human_reference_atlas synonym: "gray matter of the hindbrain" EXACT [DHBA:HGM] xref: DHBA:10654 xref: FMA:268630 is_a: UBERON:0003528 ! brain gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002028 ! hindbrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0019264 name: gray matter of forebrain namespace: uberon subset: human_reference_atlas xref: DHBA:10157 xref: FMA:268608 is_a: UBERON:0003528 ! brain gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0001890 ! forebrain relationship: part_of UBERON:0001890 ! forebrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0019267 name: gray matter of midbrain namespace: uberon subset: human_reference_atlas xref: DHBA:10649 xref: FMA:83913 is_a: UBERON:0003528 ! brain gray matter intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0001891 ! midbrain relationship: part_of UBERON:0001891 ! midbrain property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0019291 name: white matter of metencephalon namespace: uberon xref: FMA:83939 xref: HBA:9287 is_a: UBERON:0019258 ! white matter of hindbrain intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0001895 ! metencephalon relationship: part_of UBERON:0001895 ! metencephalon [Term] id: UBERON:0019292 name: white matter of pons namespace: uberon xref: FMA:83940 is_a: UBERON:0014891 ! brainstem white matter is_a: UBERON:0019291 ! white matter of metencephalon intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0000988 ! pons relationship: part_of UBERON:0000988 ! pons [Term] id: UBERON:0019293 name: white matter of pontine tegmentum namespace: uberon alt_id: UBERON:0025819 synonym: "pontine white matter tracts" EXACT [HBA:PoWM] synonym: "predominantly white regional part of pontine tegmentum" EXACT [BIRNLEX:1069] synonym: "substantia alba tegmenti pontis" EXACT [FMA:TA] synonym: "white matter of pontile tegmentum" EXACT [FMA:83942] synonym: "white substance of pontile tegmentum" EXACT [FMA:83942] xref: BIRNLEX:1069 xref: FMA:83942 xref: HBA:265505486 is_a: UBERON:0019292 ! white matter of pons intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0003023 ! pontine tegmentum relationship: part_of UBERON:0003023 ! pontine tegmentum [Term] id: UBERON:0019304 name: sensory organ epithelium namespace: uberon xref: EMAPA:35952 xref: MA:0003174 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000020 ! sense organ relationship: part_of UBERON:0000020 ! sense organ [Term] id: UBERON:0019306 name: nose epithelium namespace: uberon xref: EMAPA:35958 xref: MA:0003171 is_a: UBERON:0010371 ! ecto-epithelium is_a: UBERON:0019304 ! sensory organ epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000004 ! nose relationship: part_of UBERON:0000004 ! nose [Term] id: UBERON:0019307 name: epithelium of external nose namespace: uberon def: "Epithelial layer that is part of the external part of the nose." [http://orcid.org/0000-0002-6601-2165] synonym: "epithelium of skin of external nose" EXACT [FMA:63143] xref: FMA:63143 is_a: UBERON:0012329 {source="FMA"} ! keratinized stratified squamous epithelium is_a: UBERON:0019306 ! nose epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0007827 ! external nose relationship: part_of UBERON:0007827 ! external nose [Term] id: UBERON:0019319 name: exocrine gland of integumental system namespace: uberon def: "An exocrine gland that is part of a integumental system." [GOC:dos, http://orcid.org/0000-0002-6601-2165] synonym: "integumental exocrine gland" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "integumental system exocrine gland" EXACT [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0002365 ! exocrine gland is_a: UBERON:0003297 ! gland of integumental system intersection_of: UBERON:0002365 ! exocrine gland intersection_of: part_of UBERON:0002416 ! integumental system [Term] id: UBERON:0020358 name: accessory XI nerve nucleus namespace: uberon def: "The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) in the ventral horn. The nucleus ambiguus is classically said to provide the 'cranial component' of the accessory nerve. However, the very existence of this cranial component has been recently questioned and seen as contributing exclusively to the vagus nerve. The terminology continues to be used in describing both human anatomy, and that of other animals." [Wikipedia:Spinal_accessory_nucleus] comment: See also: Wikipedia:Spinal_accessory_nucleus synonym: "accessory neural nucleus" EXACT [FMA:83965] synonym: "accessory nucleus of anterior column of spinal cord" RELATED [NeuroNames:2003] synonym: "nucleus accessorius columnae anterioris medullae spinalis" RELATED LATIN [NeuroNames:2003] synonym: "nucleus nervi accessorii" RELATED LATIN [NeuroNames:2003] synonym: "nucleus of accessory nerve" RELATED [NeuroNames:2003] synonym: "nucleus of the accessory nerve" RELATED [NeuroNames:2003] synonym: "nucleus of the spinal accessory nerve" RELATED [NeuroNames:2003] synonym: "spinal accessory nucleus" RELATED [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37067 {source="MA:th"} xref: FMA:83965 xref: MA:0001033 xref: neuronames:2003 xref: Wikipedia:Spinal_accessory_nucleus is_a: UBERON:0000126 {source="FMA"} ! cranial nerve nucleus is_a: UBERON:0007635 ! nucleus of medulla oblongata [Term] id: UBERON:0020550 name: auricular blood vessel namespace: uberon def: "A blood vessel that supplies or drains an ear." [http://orcid.org/0000-0002-6601-2165] xref: EMAPA:37386 {source="MA:th"} xref: MA:0001226 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: connected_to UBERON:0001690 ! ear relationship: connected_to UBERON:0001690 ! ear relationship: part_of RO:0002577 ! system [Term] id: UBERON:0022248 name: cerebral nerve fasciculus namespace: uberon synonym: "cerebral fascicle" EXACT [FMA:260712] synonym: "cerebral fasciculus" EXACT [FMA:260712] synonym: "nerve fascicle of telencephalon" EXACT [] synonym: "telencephalic fascicle" EXACT [] synonym: "telencephalic nerve fascicle" EXACT [] xref: FMA:260712 is_a: UBERON:0005838 ! fasciculus of brain intersection_of: UBERON:0001019 ! nerve fasciculus intersection_of: part_of UBERON:0001893 ! telencephalon relationship: part_of UBERON:0001893 ! telencephalon [Term] id: UBERON:0022288 name: surface of eyeball namespace: uberon synonym: "surface of region of wall of eyeball" RELATED [FMA:58315] xref: FMA:58315 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0036215 ! anatomical surface region intersection_of: UBERON:0036215 ! anatomical surface region intersection_of: bounding_layer_of UBERON:0010230 ! eyeball of camera-type eye relationship: bounding_layer_of UBERON:0010230 ! eyeball of camera-type eye relationship: part_of UBERON:0010230 ! eyeball of camera-type eye [Term] id: UBERON:0022292 name: splenic arteriole namespace: uberon xref: NCIT:C33596 xref: SCTID:282511007 is_a: UBERON:0001980 ! arteriole is_a: UBERON:0003497 ! abdomen blood vessel intersection_of: UBERON:0001980 ! arteriole intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0002106 ! spleen [Term] id: UBERON:0022293 name: reproductive gland secretion namespace: uberon def: "A portion of organism substance that is secreted by a reproductive gland." [UBERON:cjm] synonym: "genital fluid" RELATED [] synonym: "genital secretion" RELATED [] synonym: "reproductive system fluid" RELATED [] synonym: "reproductive system fluid/secretion" RELATED [] synonym: "reproductive system secretion" RELATED [] is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: produced_by UBERON:0003937 ! reproductive gland relationship: produced_by UBERON:0003937 ! reproductive gland [Term] id: UBERON:0022303 name: nervous system cell part layer namespace: uberon def: "Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]." [NLX:149357] subset: cumbo synonym: "lamina" BROAD [CUMBO:CUMBO] synonym: "layer" BROAD [CUMBO:CUMBO] xref: NLX:149357 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005162 ! multi cell part structure intersection_of: UBERON:0005162 ! multi cell part structure intersection_of: has_quality PATO:0002124 ! laminar intersection_of: part_of UBERON:0001016 ! nervous system relationship: has_quality PATO:0002124 ! laminar relationship: part_of UBERON:0001016 ! nervous system property_value: editor_note "this is currently used to group some cellular layers that may not strictly conform to the CARO definition of cell-part layer. Consider genericisizing and introducing subtypes for cellular layer, fibrous layer and cell soma layer" xsd:string [Term] id: UBERON:0022350 name: visceral serous membrane namespace: uberon def: "Serous membrane layer that is adjacent to and lines an organ." [http://orcid.org/0000-0002-6601-2165] synonym: "visceral wall of serous membrane" EXACT [FMA:15860] xref: FMA:15860 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: adjacent_to UBERON:0000062 ! organ intersection_of: part_of UBERON:0000042 ! serous membrane relationship: adjacent_to UBERON:0000062 ! organ relationship: part_of UBERON:0000042 ! serous membrane [Term] id: UBERON:0022351 name: parietal serous membrane namespace: uberon def: "Serous membrane layer that lines to a body cavity." [http://orcid.org/0000-0002-6601-2165] synonym: "cavity lining" BROAD [MA:0002448] synonym: "parietal wall of serous membrane" EXACT [FMA:15859] xref: FMA:15859 xref: MA:0002448 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0004923 ! organ component layer intersection_of: UBERON:0004923 ! organ component layer intersection_of: adjacent_to UBERON:0002553 ! anatomical cavity intersection_of: part_of UBERON:0000042 ! serous membrane relationship: adjacent_to UBERON:0002553 ! anatomical cavity relationship: part_of UBERON:0000042 ! serous membrane [Term] id: UBERON:0022355 name: basal layer of endometrium namespace: uberon def: "The layer of endometrial epithelium adjacent to the uterine cavity." [Wikipedia:Endometrium#Histology] subset: human_reference_atlas synonym: "pars basalis of endometrium" EXACT [] synonym: "stratum basalis of endometrium" EXACT [FMA:86492] xref: FMA:86492 xref: NCIT:C32189 is_a: UBERON:0004811 ! endometrium epithelium intersection_of: UBERON:0004811 ! endometrium epithelium intersection_of: adjacent_to UBERON:0013769 ! uterine lumen relationship: adjacent_to UBERON:0013769 ! uterine lumen property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0022358 name: placenta blood vessel namespace: uberon def: "A blood vessel of the placenta." [GO:0060674] synonym: "placental vessel" BROAD [] xref: SCTID:280716005 is_a: UBERON:0001981 ! blood vessel is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001987 ! placenta relationship: part_of UBERON:0001987 ! placenta [Term] id: UBERON:0022361 name: lung field namespace: uberon def: "A specific region of the foregut into the area in which the lung will develop." [GOC:dph, GOC:mtg_lung] synonym: "lung field" EXACT [] xref: SCTID:34922002 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0007688 ! anlage intersection_of: UBERON:0007688 ! anlage intersection_of: has_potential_to_develop_into UBERON:0002048 ! lung relationship: has_potential_to_develop_into UBERON:0002048 ! lung relationship: part_of UBERON:0003258 ! endoderm of foregut [Term] id: UBERON:0026246 name: sacral spinal cord white matter namespace: uberon subset: human_reference_atlas synonym: "sacral spinal cord white matter" EXACT HUMAN_PREFERRED [BIRNLEX:1500] xref: BIRNLEX:1500 is_a: UBERON:0002318 ! white matter of spinal cord intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0005843 ! sacral spinal cord disjoint_from: UBERON:0029503 {source="NIFSTD"} ! sacral spinal cord gray matter relationship: part_of UBERON:0005843 ! sacral spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0026386 name: lumbar spinal cord white matter namespace: uberon subset: human_reference_atlas synonym: "lumbar spinal cord white matter" EXACT HUMAN_PREFERRED [BIRNLEX:1639] xref: BIRNLEX:1639 is_a: UBERON:0002318 ! white matter of spinal cord intersection_of: UBERON:0002316 ! white matter intersection_of: part_of UBERON:0002792 ! lumbar spinal cord disjoint_from: UBERON:0029636 {source="NIFSTD"} ! lumbar spinal cord gray matter relationship: part_of UBERON:0002792 ! lumbar spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0029503 name: sacral spinal cord gray matter namespace: uberon subset: human_reference_atlas synonym: "sacral spinal cord gray matter" EXACT HUMAN_PREFERRED [BIRNLEX:1491] xref: BIRNLEX:1491 is_a: UBERON:0002315 ! gray matter of spinal cord intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0005843 ! sacral spinal cord relationship: part_of UBERON:0005843 ! sacral spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0029636 name: lumbar spinal cord gray matter namespace: uberon subset: human_reference_atlas synonym: "lumbar spinal cord gray matter" EXACT HUMAN_PREFERRED [BIRNLEX:1624] xref: BIRNLEX:1624 is_a: UBERON:0002315 ! gray matter of spinal cord intersection_of: UBERON:0002020 ! gray matter intersection_of: part_of UBERON:0002792 ! lumbar spinal cord relationship: part_of UBERON:0002792 ! lumbar spinal cord property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0030276 name: lumbar spinal cord ventral horn namespace: uberon subset: human_reference_atlas synonym: "lumbar spinal cord anterior horn" RELATED [BIRNLEX:891] synonym: "lumbar spinal cord ventral horn" EXACT HUMAN_PREFERRED [BIRNLEX:891] xref: BIRNLEX:891 is_a: UBERON:0002257 ! ventral horn of spinal cord intersection_of: UBERON:0002257 ! ventral horn of spinal cord intersection_of: part_of UBERON:0002792 ! lumbar spinal cord relationship: part_of UBERON:0029636 ! lumbar spinal cord gray matter property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0032748 name: sacral spinal cord ventral horn namespace: uberon subset: human_reference_atlas synonym: "sacral spinal cord anterior horn" RELATED [BIRNLEX:1457] synonym: "sacral spinal cord ventral horn" EXACT HUMAN_PREFERRED [BIRNLEX:1457] xref: BIRNLEX:1457 is_a: UBERON:0002257 ! ventral horn of spinal cord intersection_of: UBERON:0002257 ! ventral horn of spinal cord intersection_of: part_of UBERON:0005843 ! sacral spinal cord relationship: part_of UBERON:0029503 ! sacral spinal cord gray matter property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0034705 name: developing neuroepithelium namespace: uberon def: "An embryonic or larval epithelium that is committed to form part of the nervous system." [AEO:0001008, AEO:JB] synonym: "embryonic neuroepithelium" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "neurepithelium" BROAD [BTO:0000314] synonym: "neuroepithelium" EXACT [AEO:0001008] xref: AEO:0001008 xref: BTO:0000314 xref: EHDAA2_RETIRED:0004654 xref: FMA:64807 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000483 ! epithelium relationship: part_of UBERON:0001016 ! nervous system [Term] id: UBERON:0034706 name: proliferating neuroepithelium namespace: uberon def: "An epithelium that is undergoing proliferation to provide large numbers of neuronal cells." [AEO:0001009] xref: AEO:0001009 is_a: UBERON:0034705 {source="AEO"} ! developing neuroepithelium [Term] id: UBERON:0034707 name: differentiating neuroepithelium namespace: uberon def: "A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells." [AEO:0001010] xref: AEO:0001010 is_a: UBERON:0034705 {source="AEO"} ! developing neuroepithelium relationship: has_part CL:0000031 ! neuroblast (sensu Vertebrata) [Term] id: UBERON:0034709 name: hindbrain marginal layer namespace: uberon synonym: "marginal zone of hindbrain" EXACT [DHBA:12694] synonym: "MZH" RELATED ABBREVIATION [DHBA:12694] xref: DHBA:12694 xref: EMAPA:32916 is_a: UBERON:0004062 ! neural tube marginal layer is_a: UBERON:0011215 ! central nervous system cell part cluster intersection_of: UBERON:0004062 ! neural tube marginal layer intersection_of: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0034710 name: spinal cord ventricular layer namespace: uberon synonym: "spinal cord lateral wall ventricular layer" EXACT [EHDAA2:0001267] xref: EHDAA2:0001267 xref: EMAPA:17585 is_a: UBERON:0004060 ! neural tube ventricular layer intersection_of: UBERON:0004060 ! neural tube ventricular layer intersection_of: part_of UBERON:0006241 ! future spinal cord relationship: part_of UBERON:0005496 {source="EHDAA2"} ! neural tube lateral wall relationship: part_of UBERON:0006241 ! future spinal cord [Term] id: UBERON:0034711 name: cortical preplate namespace: uberon def: "The layer of the developing cerebral cortex that is formed from the first cohort of neurons to migrate out of the cortical ventricular zone; split by the second wave into marginal zone and subplate." [PMID:12626695] xref: EMAPA:35261 is_a: UBERON:0014950 ! layer of developing cerebral cortex [Term] id: UBERON:0034713 name: cranial neuron projection bundle namespace: uberon def: "Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain." [http://orcid.org/0000-0002-6601-2165, ISBN:0471888893] subset: human_reference_atlas synonym: "cranial nerve fiber bundle" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "cranial nerve fiber tract" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "cranial nerve or tract" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "neuron projection bundle from brain" RELATED [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0000122 ! neuron projection bundle is_a: UBERON:0015212 ! lateral structure relationship: extends_fibers_into UBERON:0000955 ! brain relationship: in_lateral_side_of UBERON:0000033 ! head relationship: only_in_taxon NCBITaxon:89593 ! Craniata relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000033 ! head property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0034717 name: integumental taste bud namespace: uberon def: "A taste bud that is located external to the digestive tube, on the head or body, as found in species such as goldfish." [http://orcid.org/0000-0002-6601-2165, PMID:11921337] is_a: UBERON:0001727 ! taste bud intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0002416 ! integumental system relationship: part_of UBERON:0002416 ! integumental system [Term] id: UBERON:0034719 name: lip taste bud namespace: uberon def: "A taste bud that is located on a lip." [http://orcid.org/0000-0002-6601-2165, PMID:11921337] is_a: UBERON:0001727 ! taste bud is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0001833 ! lip relationship: part_of UBERON:0001833 ! lip property_value: RO:0002175 NCBITaxon:32443 [Term] id: UBERON:0034720 name: head taste bud namespace: uberon def: "A taste bud that is located on the skin of the head." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034717 ! integumental taste bud intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0001084 ! skin of head relationship: part_of UBERON:0001084 ! skin of head [Term] id: UBERON:0034721 name: pharyngeal taste bud namespace: uberon def: "A taste bud that is located in the pharynx." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0001727 ! taste bud is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0006562 ! pharynx relationship: part_of UBERON:0000355 ! pharyngeal mucosa property_value: RO:0002175 NCBITaxon:7778 [Term] id: UBERON:0034722 name: mouth roof taste bud namespace: uberon def: "A taste bud that is located on the roof of the mouth." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0001727 ! taste bud intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0007375 ! roof of mouth relationship: part_of UBERON:0007375 ! roof of mouth property_value: RO:0002175 NCBITaxon:7778 [Term] id: UBERON:0034724 name: esophageal taste bud namespace: uberon def: "A taste bud that is located in the esophagus." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0001727 ! taste bud is_a: UBERON:0005181 ! thoracic segment organ is_a: UBERON:0013765 ! digestive system element intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0001043 ! esophagus relationship: part_of UBERON:0001043 ! esophagus property_value: RO:0002175 NCBITaxon:32443 [Term] id: UBERON:0034726 name: trunk taste bud namespace: uberon def: "A taste bud that is located on the skin of the trunk." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0005177 ! trunk region element is_a: UBERON:0034717 ! integumental taste bud intersection_of: UBERON:0001727 ! taste bud intersection_of: part_of UBERON:0001085 ! skin of trunk relationship: part_of UBERON:0001085 ! skin of trunk [Term] id: UBERON:0034728 name: autonomic nerve namespace: uberon def: "The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa." [Wikipedia:Autonomic_nerve] synonym: "nervus visceralis" EXACT [FMA:5866] synonym: "visceral nerve" EXACT [FMA:5866] xref: EMAPA:37957 {source="MA:th"} xref: FMA:5866 xref: MESH:D017776 xref: SCTID:276145003 xref: Wikipedia:Autonomic_nerve is_a: UBERON:0011779 ! nerve of head region relationship: branching_part_of UBERON:0036264 ! zygomaticotemporal nerve relationship: extends_fibers_into UBERON:0001805 ! autonomic ganglion relationship: part_of UBERON:0002410 ! autonomic nervous system relationship: part_of UBERON:0036264 ! zygomaticotemporal nerve [Term] id: UBERON:0034729 name: sympathetic nerve namespace: uberon subset: human_reference_atlas xref: EMAPA:37958 {source="MA:th"} xref: SCTID:181098007 is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: part_of UBERON:0000013 ! sympathetic nervous system relationship: extends_fibers_into UBERON:0001806 ! sympathetic ganglion relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000013 ! sympathetic nervous system property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0034768 name: morphological feature namespace: uberon def: "A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy is_a: UBERON:0000061 ! anatomical structure relationship: has_quality PATO:0000052 ! shape relationship: part_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0034769 name: lymphomyeloid tissue namespace: uberon xref: FMA:79770 xref: NCIT:C41168 is_a: UBERON:0015757 {source="FMA"} ! heterogeneous tissue [Term] id: UBERON:0034873 name: bodily gas namespace: uberon def: "Any substance in the body or expelled from the body that is in a gaseous state." [http://orcid.org/0000-0002-6601-2165] synonym: "gas in anatomical space" EXACT [] synonym: "portion of gas in anatomical space" EXACT [FMA:84580] xref: FMA:84580 is_a: UBERON:0000463 ! organism substance intersection_of: UBERON:0000463 ! organism substance intersection_of: has_quality PATO:0001547 ! quality of a gas relationship: has_quality PATO:0001547 ! quality of a gas [Term] id: UBERON:0034874 name: air in respiratory system namespace: uberon def: "Any portion of gas located in a part of the respiratory system that is composed primarily of air." [http://orcid.org/0000-0002-6601-2165] synonym: "respiratory air" EXACT [FMA:84581] synonym: "respiratory system air" EXACT [] xref: FMA:84581 is_a: UBERON:0034947 ! gas in respiratory system intersection_of: UBERON:0034873 ! bodily gas intersection_of: composed_primarily_of CHEBI:25805 ! oxygen atom intersection_of: located_in UBERON:0001004 ! respiratory system relationship: composed_primarily_of CHEBI:25805 ! oxygen atom [Term] id: UBERON:0034878 name: prechordal mesoderm namespace: uberon def: "The area of axial mesoderm that develops into the prechordal plate." [MGI:anna] synonym: "prechordal mesenchyme" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002050 ! embryonic structure intersection_of: UBERON:0005423 ! developing anatomical structure intersection_of: has_potential_to_develop_into UBERON:0003063 ! prechordal plate intersection_of: part_of UBERON:0003068 ! axial mesoderm relationship: has_potential_to_develop_into UBERON:0003063 ! prechordal plate relationship: part_of UBERON:0003068 ! axial mesoderm [Term] id: UBERON:0034898 name: alveolar ridge of premaxilla namespace: uberon def: "The thickened ridge of bone that contains the tooth sockets on the premaxilla." [http://orcid.org/0000-0002-6601-2165] synonym: "pars dentalis of premaxilla" EXACT [AAO:0000397] xref: AAO:0000397 is_a: UBERON:0004103 ! alveolar ridge intersection_of: UBERON:0004103 ! alveolar ridge intersection_of: part_of UBERON:0002244 ! premaxilla relationship: part_of UBERON:0002244 {source="AAO"} ! premaxilla [Term] id: UBERON:0034903 name: left atrium endocardium namespace: uberon def: "Endocardium that is part of the left atrium." [http://orcid.org/0000-0002-6601-2165] synonym: "endocardium of left atrium" EXACT [FMA:7286] synonym: "left atrial endocardium" EXACT [] synonym: "left atrium endocardial tissue" RELATED [VHOG:0001226] xref: FMA:7286 xref: SCTID:190064008 xref: VHOG:0001226 is_a: UBERON:0002166 ! endocardium of atrium intersection_of: UBERON:0002165 ! endocardium intersection_of: part_of UBERON:0002079 ! left cardiac atrium relationship: part_of UBERON:0002079 ! left cardiac atrium property_value: UBPROP:0000001 "Endocardium of atrium which is continuous with the tunica intima of the trunk of pulmonary vein." xsd:string {source="FMA:7286"} [Term] id: UBERON:0034905 name: gland lumen namespace: uberon synonym: "lumen of gland" EXACT [] is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0002530 ! gland relationship: luminal_space_of UBERON:0002530 ! gland relationship: part_of UBERON:0002530 ! gland [Term] id: UBERON:0034908 name: scapular muscle namespace: uberon def: "Any of the muscles that are responsible for moving the scapula. In humans these are the levator scapulae, the infraspinatus muscle, the teres major, the teres minor, and the supraspinatus muscle." [HPO:curators] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0014892 ! skeletal muscle organ intersection_of: UBERON:0014892 ! skeletal muscle organ intersection_of: attaches_to UBERON:0006849 ! scapula relationship: attaches_to UBERON:0006849 ! scapula [Term] id: UBERON:0034909 name: intermaxillary suture namespace: uberon def: "A cranial suture in the midline of the skull that connects the left and right maxilla bones." [http://www.researchgate.net/publication/255909975_Relationship_between_intermaxillary_suture_and_midline_diastema, https://orcid.org/0000-0001-5889-4463] comment: in humans, the upper maxillae (the upper jaw) is composed of the right and left maxilla bones, which are fused in the midline at the intermaxillary suture to form the upper jaw.[https://orcid.org/0000-0001-5889-4463] synonym: "intermaxillary suture of skull" EXACT [FMA:52963] xref: FMA:52963 is_a: UBERON:0003685 ! cranial suture is_a: UBERON:0009199 ! facial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0002397 {cardinality="2"} ! maxilla relationship: connects UBERON:0002397 ! maxilla relationship: part_of UBERON:0001709 ! upper jaw region [Term] id: UBERON:0034921 name: multi organ part structure namespace: uberon def: "An multicellular anatomical structure that has subparts of multiple organs as a part." [CARO:0020001] subset: common_anatomy synonym: "anatomical cluster" RELATED [CARO:0020001] xref: CARO:0020001 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: composed_primarily_of UBERON:0000064 ! organ part property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0034922 name: cell cluster namespace: uberon def: "A cluster of cells, largely surrounded by a morphological boundary." [CARO:0020002] subset: common_anatomy xref: CARO:0020002 xref: FMA:62807 is_a: UBERON:0010000 {source="CARO"} ! multicellular anatomical structure relationship: surrounded_by UBERON:0000015 ! non-material anatomical boundary property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0034923 name: disconnected anatomical group namespace: uberon def: "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." [CARO:0020000] subset: common_anatomy xref: CARO:0020000 xref: FBbt:00007276 is_a: UBERON:0000465 {source="CARO"} ! material anatomical entity relationship: composed_primarily_of UBERON:0000061 ! anatomical structure relationship: has_component UBERON:0000061 {minCardinality="2"} ! anatomical structure relationship: has_quality PATO:0010001 ! disconnected property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0034925 name: anatomical collection namespace: uberon def: "A collection of anatomical structures that are alike in terms of their morphology or developmental origin." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy is_a: UBERON:0000465 ! material anatomical entity relationship: has_member UBERON:0000061 ! anatomical structure property_value: editor_note "resolve if this should be a subclass of disconnected anatomical group. Some collections (e.g. the skeleton or skull) are arguably connected" xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0034926 name: anatomical row namespace: uberon def: "An anatomical collection that is arranged in a line." [http://orcid.org/0000-0002-6601-2165] subset: common_anatomy xref: FBbt:00100152 is_a: UBERON:0034925 ! anatomical collection property_value: editor_note "resolve if this should be a subclass of or merged with aligned anatomical group." xsd:string property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0034928 name: dorsal surface of penis namespace: uberon synonym: "dorsum of penis" EXACT [FMA:19623] synonym: "dorsum penis" EXACT [FMA:TA] xref: FMA:19623 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0036215 ! anatomical surface region intersection_of: UBERON:0036215 ! anatomical surface region intersection_of: in_dorsal_side_of UBERON:0000989 ! penis relationship: in_dorsal_side_of UBERON:0000989 ! penis relationship: part_of UBERON:0000989 ! penis [Term] id: UBERON:0034929 name: external soft tissue zone namespace: uberon def: "A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures." [http://orcid.org/0000-0002-6601-2165] is_a: CARO:0000000 ! anatomical entity is_a: PR:000050567 ! protein-containing material entity is_a: UBERON:0010000 ! multicellular anatomical structure relationship: has_part UBERON:0000014 ! zone of skin relationship: has_part UBERON:0001015 ! musculature relationship: has_part UBERON:0001021 ! nerve relationship: has_part UBERON:0002049 ! vasculature relationship: part_of UBERON:0000475 ! organism subdivision [Term] id: UBERON:0034932 name: epithelium of biliary system namespace: uberon def: "The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts." [BTO:0001513, http://orcid.org/0000-0002-6601-2165, MGI:cs] synonym: "biliary epithelium" RELATED [BTO:0001513] synonym: "biliary system epithelium" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "biliary tract epithelium" RELATED [http://orcid.org/0000-0002-6601-2165] xref: BTO:0001513 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0002294 ! biliary system relationship: part_of UBERON:0002294 ! biliary system [Term] id: UBERON:0034933 name: layer of smooth muscle tissue namespace: uberon def: "Any organ component layer that consists of smooth muscle tissue." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0018260 ! layer of muscle tissue intersection_of: UBERON:0004923 ! organ component layer intersection_of: composed_primarily_of UBERON:0001135 ! smooth muscle tissue relationship: composed_primarily_of UBERON:0001135 ! smooth muscle tissue [Term] id: UBERON:0034944 name: zone of organ namespace: uberon synonym: "organ region with floating fiat boundary" RELATED [FMA:55268] synonym: "organ sector" EXACT [FMA:55268] synonym: "organ zonal region" EXACT [] synonym: "organ zone" EXACT [FMA:55268] xref: FMA:55268 is_a: UBERON:0000064 ! organ part [Term] id: UBERON:0034945 name: excreted gas namespace: uberon def: "Any gaseous product of an excretory process." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0000174 ! excreta is_a: UBERON:0034873 ! bodily gas intersection_of: UBERON:0034873 ! bodily gas intersection_of: output_of GO:0007588 ! excretion [Term] id: UBERON:0034946 name: gas excreted from digestive tract namespace: uberon def: "Any excreted gas that is produced by the digestive tract." [http://orcid.org/0000-0002-6601-2165] comment: In mammals, mostly produced as a byproduct of bacterial fermentation in the gastrointestinal (GI) tract, especially the colon, and excreted through the rectum synonym: "flatulence" NARROW [FMA:78440] synonym: "flatus" NARROW LATIN [Wikipedia:Flatulence] synonym: "intestinal gas" NARROW [] xref: FMA:78440 is_a: UBERON:0034945 ! excreted gas intersection_of: UBERON:0034945 ! excreted gas intersection_of: produced_by UBERON:0001555 ! digestive tract relationship: produced_by UBERON:0001555 ! digestive tract [Term] id: UBERON:0034947 name: gas in respiratory system namespace: uberon def: "Any portion of gas located in a part of the respiratory system." [http://orcid.org/0000-0002-6601-2165] synonym: "respiratory gas" EXACT [] synonym: "respiratory system gas" EXACT [] is_a: UBERON:0034873 ! bodily gas intersection_of: UBERON:0034873 ! bodily gas intersection_of: located_in UBERON:0001004 ! respiratory system relationship: located_in UBERON:0001004 ! respiratory system [Term] id: UBERON:0034969 name: epithelial layer of duct namespace: uberon synonym: "duct epithelium" RELATED [] synonym: "ductal epithelium" RELATED [] xref: NCIT:C25787 xref: UMLS:C1512086 is_a: UBERON:0003914 ! epithelial tube intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000058 ! duct relationship: part_of UBERON:0000058 ! duct [Term] id: UBERON:0034983 name: ischial tuberosity namespace: uberon def: "A horizontal thickening onto which the muscles of the femur, such as the quadriceps and hamstring, attach." [MURDOCH:1034] synonym: "ischial tuberosities" RELATED [Wikipedia:Tuberosity_of_the_ischium] synonym: "ischial tuberosity" RELATED [Wikipedia:Tuberosity_of_the_ischium] synonym: "tuber ischiadicum" RELATED [Wikipedia:Tuberosity_of_the_ischium] synonym: "tuber ischiale" EXACT [FMA:17010] xref: FMA:17010 xref: NCIT:C105446 xref: SCTID:182041003 xref: Wikipedia:Tuberosity_of_the_ischium is_a: UBERON:0005813 {source="FMA"} ! tubercle [Term] id: UBERON:0034994 name: hindbrain cortical intermediate zone namespace: uberon synonym: "hindbrain mantle layer" EXACT [EMAPA:32917] xref: DHBA:12682 xref: EMAPA:32917 is_a: UBERON:0004040 ! cortical intermediate zone intersection_of: UBERON:0004040 ! cortical intermediate zone intersection_of: part_of UBERON:0002028 ! hindbrain relationship: part_of UBERON:0002028 ! hindbrain [Term] id: UBERON:0034995 name: jaw mesenchyme namespace: uberon def: "Mesenchyme that is part of a developing jaw [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:32907 xref: EMAPA:35454 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0005253 ! head mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0011595 ! jaw region relationship: part_of UBERON:0011595 ! jaw region [Term] id: UBERON:0035036 name: naris epithelium namespace: uberon def: "An epithelium that is part of a naris [Automatically generated definition]." [OBOL:automatic] xref: EMAPA:35959 xref: MA:0003172 is_a: UBERON:0000483 ! epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0000003 ! naris relationship: part_of UBERON:0000003 ! naris [Term] id: UBERON:0035037 name: jaw epithelium namespace: uberon xref: EMAPA:32904 xref: MA:0003220 is_a: UBERON:0003929 ! digestive tract epithelium intersection_of: UBERON:0000483 ! epithelium intersection_of: part_of UBERON:0011595 ! jaw region relationship: part_of UBERON:0011595 ! jaw region [Term] id: UBERON:0035039 name: rectal artery namespace: uberon synonym: "hemorrhoidal artery" EXACT [] xref: SCTID:277967008 is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001052 ! rectum relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0001052 ! rectum [Term] id: UBERON:0035050 name: excretory duct namespace: uberon is_a: UBERON:0000058 ! duct [Term] id: UBERON:0035083 name: transverse process-bearing vertebra namespace: uberon def: "A vertebra that has a transverse process." [http://orcid.org/0000-0002-6601-2165] synonym: "pygal vertebra" RELATED [PMID:22753107] synonym: "TP vertebra" RELATED [PMID:22753107] is_a: UBERON:0002412 ! vertebra intersection_of: UBERON:0002412 ! vertebra intersection_of: has_part UBERON:0001077 ! transverse process of vertebra relationship: has_part UBERON:0001077 ! transverse process of vertebra [Term] id: UBERON:0035091 name: extrinsic post-anal tail muscle namespace: uberon def: "A post-anal tail that attaches outside the tail." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0003665 ! post-anal tail muscle intersection_of: UBERON:0003665 ! post-anal tail muscle intersection_of: attaches_to UBERON:0010742 ! bone of pelvic complex relationship: attaches_to UBERON:0010742 ! bone of pelvic complex [Term] id: UBERON:0035102 name: transverse process of caudal vertebra namespace: uberon def: "A transverse process that is part of a caudal vertebra." [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:0001077 ! transverse process of vertebra intersection_of: UBERON:0001077 ! transverse process of vertebra intersection_of: part_of UBERON:0001095 ! caudal vertebra relationship: part_of UBERON:0001095 ! caudal vertebra [Term] id: UBERON:0035115 name: diastema between central incisors namespace: uberon def: "A space or gap between the left and right central incisors, on either the upper or lower jaw." [http://orcid.org/0000-0002-6601-2165] synonym: "interdental space, central incisors" EXACT [] synonym: "midline diastema" EXACT [] is_a: UBERON:0035119 ! diastema between incisors intersection_of: UBERON:0035119 ! diastema between incisors intersection_of: adjacent_to UBERON:0018551 {cardinality="2"} ! central incisor tooth relationship: adjacent_to UBERON:0018551 ! central incisor tooth [Term] id: UBERON:0035116 name: diastema between upper central incisors namespace: uberon def: "A space or gap between the left and right central incisors on the upper jaw." [http://orcid.org/0000-0002-6601-2165] synonym: "interdental space between maxillary central incisors" EXACT [] synonym: "interdental space, upper central incisors" EXACT [] synonym: "midline maxillary diastema" EXACT [] is_a: UBERON:0035115 ! diastema between central incisors intersection_of: UBERON:0035115 ! diastema between central incisors intersection_of: part_of UBERON:0001709 ! upper jaw region relationship: adjacent_to UBERON:0018603 {cardinality="2"} ! upper central incisor tooth relationship: intersects_midsagittal_plane_of UBERON:0003277 ! skeleton of upper jaw relationship: part_of UBERON:0003277 ! skeleton of upper jaw [Term] id: UBERON:0035117 name: diastema between lower central incisors namespace: uberon def: "A space or gap between the left and right central incisors on the lower jaw." [http://orcid.org/0000-0002-6601-2165] synonym: "interdental space between mandibular central incisors" EXACT [] synonym: "interdental space, lower central incisors" EXACT [] synonym: "midline mandibular diastema" EXACT [] is_a: UBERON:0035115 ! diastema between central incisors intersection_of: UBERON:0035115 ! diastema between central incisors intersection_of: part_of UBERON:0001710 ! lower jaw region relationship: adjacent_to UBERON:0018601 {cardinality="2"} ! lower central incisor tooth relationship: intersects_midsagittal_plane_of UBERON:0003278 ! skeleton of lower jaw relationship: part_of UBERON:0003278 ! skeleton of lower jaw [Term] id: UBERON:0035118 name: material entity in digestive tract namespace: uberon def: "Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included." [https://github.com/EnvironmentOntology/envo/issues/110] synonym: "digestive tract contents" EXACT PLURAL [] synonym: "ingested material entity" RELATED [] is_a: UBERON:0000061 ! anatomical structure intersection_of: UBERON:0000061 ! anatomical structure intersection_of: located_in UBERON:0006909 ! lumen of digestive tract relationship: located_in UBERON:0006909 ! lumen of digestive tract property_value: editor_note "Note that we treat any material entity that is ingested as an anatomical structure by defintion, although this may be expanding the CARO usage somewhat" xsd:string [Term] id: UBERON:0035119 name: diastema between incisors namespace: uberon def: "A space or gap any two incisors. This may be a midline diastema between central incisors, or a diastema located entirely in a single jaw quadrant between lateral incisors." [http://orcid.org/0000-0002-6601-2165] synonym: "incisor diastema" EXACT [] synonym: "interdental space, incisors" EXACT [] is_a: UBERON:0012111 ! diastema intersection_of: UBERON:0012111 ! diastema intersection_of: adjacent_to UBERON:0001098 {cardinality="2"} ! incisor tooth relationship: adjacent_to UBERON:0001098 ! incisor tooth relationship: intersects_midsagittal_plane_of UBERON:0001708 ! jaw skeleton [Term] id: UBERON:0035127 name: suture of hard palate namespace: uberon def: "Any of the sutures of the hard palate." [http://www.merriam-webster.com/medical/palatine%20suture] synonym: "palatine suture" EXACT [http://www.merriam-webster.com/medical/palatine%20suture] is_a: UBERON:0003685 ! cranial suture is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0003685 ! cranial suture intersection_of: part_of UBERON:0003216 ! hard palate relationship: part_of UBERON:0003216 ! hard palate [Term] id: UBERON:0035128 name: manus cartilage element namespace: uberon synonym: "hand cartilage condensation" EXACT [EMAPA:32631] xref: EMAPA:32631 is_a: UBERON:0010883 ! forelimb cartilage element is_a: UBERON:0015064 ! autopod cartilage intersection_of: UBERON:0015063 ! autopod endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0002398 ! manus relationship: develops_from UBERON:0009523 {source="EMAPA-modified"} ! mesenchyme of handplate relationship: part_of UBERON:0002398 ! manus [Term] id: UBERON:0035129 name: pes cartilage element namespace: uberon synonym: "foot cartilage condensation" EXACT [EMAPA:32657] xref: EMAPA:32657 is_a: UBERON:0010885 ! hindlimb cartilage element is_a: UBERON:0015064 ! autopod cartilage intersection_of: UBERON:0015063 ! autopod endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue intersection_of: part_of UBERON:0002387 ! pes relationship: develops_from UBERON:0003328 {source="EMAPA-modified"} ! mesenchyme of footplate relationship: part_of UBERON:0002387 ! pes [Term] id: UBERON:0035130 name: auditory ossicle endochondral element namespace: uberon synonym: "auditory skeletal element" EXACT [] synonym: "ear ossicle element" RELATED [] synonym: "ear ossicles element" RELATED PLURAL [] synonym: "middle ear ossicle element" EXACT [MP:0005105] synonym: "middle ear skeletal element" RELATED [] synonym: "ossicle element" BROAD [EMAPA:17824, Wikipedia:Auditory_ossicle] synonym: "ossicle element of ear" RELATED [] synonym: "ossicle element of inner ear" RELATED [] synonym: "ossicular chain element" RELATED PLURAL [] is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:0010363 ! endochondral element relationship: contributes_to_morphology_of UBERON:0001756 ! middle ear relationship: develops_from UBERON:0003099 {source="PMID:11237469", source="https://github.com/obophenotype/uberon/wiki/The-neural-crest"} ! cranial neural crest relationship: part_of UBERON:0001756 {source="MA"} ! middle ear relationship: part_of UBERON:0008895 {source="PMID:11523816"} ! splanchnocranium [Term] id: UBERON:0035131 name: auditory ossicle cartilage element namespace: uberon synonym: "ossicle cartilage condensation" EXACT [EMAPA:35979] xref: EMAPA:35979 is_a: UBERON:0011004 ! pharyngeal arch cartilage is_a: UBERON:0035130 ! auditory ossicle endochondral element intersection_of: UBERON:0035130 ! auditory ossicle endochondral element intersection_of: composed_primarily_of UBERON:0002418 ! cartilage tissue [Term] id: UBERON:0035132 name: auditory ossicle pre-cartilage element namespace: uberon synonym: "ossicle pre-cartilage condensation" EXACT [EMAPA:35982] xref: EMAPA:35982 is_a: UBERON:0035130 ! auditory ossicle endochondral element intersection_of: UBERON:0035130 ! auditory ossicle endochondral element intersection_of: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation relationship: composed_primarily_of UBERON:0005866 ! pre-cartilage condensation [Term] id: UBERON:0035159 name: entire surface of organism namespace: uberon def: "Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface." [FMA:61695] synonym: "surface of body" EXACT [FMA:61695] xref: FMA:61695 xref: NCIT:C29667 xref: SCTID:261060002 xref: UMLS:C0489451 is_a: UBERON:0006984 ! anatomical surface intersection_of: UBERON:0006984 ! anatomical surface intersection_of: surrounds UBERON:0000468 ! multicellular organism relationship: surrounds UBERON:0000468 ! multicellular organism [Term] id: UBERON:0035174 name: right ear namespace: uberon def: "The organ of hearing located on the right side of the head." [ncithesaurus:Right_Ear] xref: FMA:53641 xref: NCIT:C81285 xref: SCTID:368570004 xref: UMLS:C0229298 is_a: UBERON:0001690 ! ear is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001690 ! ear intersection_of: in_right_side_of UBERON:0000033 ! head relationship: in_right_side_of UBERON:0000033 ! head [Term] id: UBERON:0035237 name: branch of internal carotid artery namespace: uberon synonym: "internal carotid arterial subdivision" EXACT [FMA:70506] synonym: "subdivision of internal carotid artery" EXACT [FMA:70506] xref: FMA:70506 xref: NCIT:C32837 xref: SCTID:360629008 xref: UMLS:C1182571 is_a: UBERON:0003496 ! head blood vessel is_a: UBERON:0005396 ! carotid artery segment intersection_of: UBERON:0005396 ! carotid artery segment intersection_of: branching_part_of UBERON:0001532 ! internal carotid artery relationship: branching_part_of UBERON:0001532 ! internal carotid artery relationship: part_of UBERON:0001532 ! internal carotid artery [Term] id: UBERON:0035267 name: neck of gallbladder namespace: uberon def: "The narrowest portion of the gallbladder and distal to the cystic duct." [ncithesaurus:Gallbladder_Neck] synonym: "cervix of gallbladder" EXACT [FMA:14538] synonym: "gallbladder neck" EXACT [FMA:14538] xref: FMA:14538 xref: NCIT:C32649 xref: SCTID:245394007 xref: UMLS:C0227546 xref: Wikipedia:Neck_of_gallbladder is_a: UBERON:0001560 ! neck of organ is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 ! gallbladder [Term] id: UBERON:0035295 name: left ear namespace: uberon def: "The organ of hearing located on the left side of the head[ncit,modified]." [http://orcid.org/0000-0002-6601-2165, ncithesaurus:Left_Ear] xref: FMA:53642 xref: NCIT:C81259 xref: SCTID:368592000 xref: UMLS:C0229299 is_a: UBERON:0001690 ! ear is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001690 ! ear intersection_of: in_left_side_of UBERON:0000033 ! head relationship: in_left_side_of UBERON:0000033 ! head [Term] id: UBERON:0035322 name: right common iliac artery namespace: uberon subset: human_reference_atlas synonym: "trunk of right common iliac arterial tree" EXACT [FMA:14765] xref: FMA:14765 xref: NCIT:C33474 xref: SCTID:283392005 xref: UMLS:C0226362 is_a: UBERON:0001191 ! common iliac artery is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001191 ! common iliac artery intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: in_right_side_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0035383 name: lateral wall of nasopharynx namespace: uberon synonym: "lateral nasopharynx" EXACT [FMA:54908] xref: FMA:54908 xref: NCIT:C12244 xref: SCTID:361937006 xref: UMLS:C0225486 is_a: UBERON:0000328 ! gut wall is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: in_lateral_side_of UBERON:0001728 ! nasopharynx intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: in_lateral_side_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001728 ! nasopharynx [Term] id: UBERON:0035398 name: branch of external carotid artery namespace: uberon synonym: "external carotid arterial subdivision" EXACT [FMA:70505] synonym: "subdivision of external carotid artery" EXACT [FMA:70505] xref: FMA:70505 xref: NCIT:C32552 xref: SCTID:244216003 xref: UMLS:C0447038 is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: branching_part_of UBERON:0001070 ! external carotid artery relationship: branching_part_of UBERON:0001070 ! external carotid artery relationship: part_of UBERON:0001070 ! external carotid artery [Term] id: UBERON:0035401 name: posterior wall of nasopharynx namespace: uberon synonym: "posterior nasopharynx" EXACT [FMA:54907] xref: FMA:54907 xref: NCIT:C12243 xref: SCTID:361936002 xref: UMLS:C0225484 is_a: UBERON:0000328 ! gut wall is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: in_posterior_side_of UBERON:0001728 ! nasopharynx intersection_of: part_of UBERON:0001728 ! nasopharynx relationship: in_posterior_side_of UBERON:0001728 ! nasopharynx relationship: part_of UBERON:0001728 ! nasopharynx [Term] id: UBERON:0035431 name: mediastinal pleura namespace: uberon def: "The parietal pleura that lines the mediastinum." [ncithesaurus:Mediastinal_Pleura] synonym: "mediastinal part of parietal pleura" EXACT [FMA:9736] synonym: "pars mediastinalis (pleurae)" EXACT [FMA:9736] synonym: "pars mediastinalis pleurae parietalis" EXACT LATIN [FMA:9736, FMA:TA] xref: FMA:9736 xref: NCIT:C94820 xref: SCTID:362002008 xref: UMLS:C0225789 xref: Wikipedia:Mediastinal_pleura is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0034944 ! zone of organ relationship: has_part UBERON:0003728 {source="FMA"} ! mediastinum relationship: part_of UBERON:0002400 {source="FMA"} ! parietal pleura [Term] id: UBERON:0035471 name: posterior surface of kidney namespace: uberon synonym: "facies posterior (Ren)" EXACT [FMA:15590] synonym: "facies posterior renis" EXACT LATIN [FMA:15590, FMA:TA] xref: FMA:15590 xref: NCIT:C32895 xref: SCTID:279376000 xref: UMLS:C0227610 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0036215 ! anatomical surface region intersection_of: UBERON:0036215 ! anatomical surface region intersection_of: bounding_layer_of UBERON:0002113 ! kidney intersection_of: in_posterior_side_of UBERON:0002113 ! kidney relationship: bounding_layer_of UBERON:0002113 ! kidney relationship: in_posterior_side_of UBERON:0002113 ! kidney relationship: part_of UBERON:0002113 ! kidney [Term] id: UBERON:0035529 name: left common iliac artery namespace: uberon subset: human_reference_atlas synonym: "trunk of left common iliac arterial tree" EXACT [FMA:14766] xref: FMA:14766 xref: NCIT:C32957 xref: SCTID:283493001 xref: UMLS:C0226363 is_a: UBERON:0001191 ! common iliac artery is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001191 ! common iliac artery intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: in_left_side_of UBERON:0000468 ! multicellular organism property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0035539 name: esophageal artery namespace: uberon def: "Any of several arteries that arise from the aorta and supply blood to the esophagus." [ncithesaurus:Esophageal_Artery] subset: human_reference_atlas synonym: "aortic esophageal artery" EXACT [FMA:4149] synonym: "oesophageal artery" EXACT [FMA:4149] xref: FMA:4149 xref: NCIT:C32535 xref: SCTID:56548006 xref: UMLS:C0226294 is_a: UBERON:0003834 ! thoracic segment blood vessel is_a: UBERON:0004573 {source="FMA"} ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001043 ! esophagus relationship: branching_part_of UBERON:0001515 {source="FMA"} ! thoracic aorta relationship: connected_to UBERON:0002345 ! descending thoracic aorta relationship: part_of UBERON:0001515 ! thoracic aorta relationship: supplies UBERON:0001043 ! esophagus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0035546 name: uveal vein namespace: uberon synonym: "ciliary vein" EXACT [FMA:51797] xref: FMA:51797 xref: SCTID:149683007 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001768 ! uvea relationship: drains UBERON:0001768 ! uvea relationship: part_of RO:0002577 ! system [Term] id: UBERON:0035548 name: colic artery namespace: uberon xref: SCTID:77852007 is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001155 ! colon relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0001155 ! colon [Term] id: UBERON:0035549 name: vasculature of integument namespace: uberon def: "The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin." [http://orcid.org/0000-0002-6601-2165] subset: human_reference_atlas synonym: "dermis vasculature" NARROW [] synonym: "hypodermis vasculature" NARROW [] synonym: "skin vasculature" RELATED [] synonym: "subcutaneous vasculature" RELATED [] synonym: "superficial part of circulatory system" EXACT [] synonym: "superficial vasculature" EXACT [] synonym: "vasculature of skin" RELATED [FMA:225275] xref: FMA:225275 is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: located_in UBERON:0002199 ! integument relationship: capable_of_part_of GO:0001659 ! temperature homeostasis relationship: located_in UBERON:0002199 ! integument property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0035550 name: superficial vein namespace: uberon def: "Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers." [ncithesaurus:Superficial_Vein] synonym: "superfical vein" RELATED [Wikipedia:Superficial_vein] synonym: "superficial veins" RELATED [Wikipedia:Superficial_vein] synonym: "superficial vessels" RELATED [Wikipedia:Superficial_vein] xref: FMA:76719 xref: NCIT:C33666 xref: SCTID:341382008 xref: UMLS:C0226513 xref: Wikipedia:Superficial_vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0035549 ! vasculature of integument relationship: part_of UBERON:0035549 ! vasculature of integument [Term] id: UBERON:0035551 name: deep vasculature namespace: uberon def: "The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin." [http://orcid.org/0000-0002-6601-2165] synonym: "deep part of circulatory system" EXACT [] is_a: UBERON:0002049 ! vasculature intersection_of: UBERON:0002049 ! vasculature intersection_of: deep_to UBERON:0002199 ! integument relationship: deep_to UBERON:0002199 ! integument [Term] id: UBERON:0035552 name: deep vein namespace: uberon def: "A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery." [ncithesaurus:Deep_Vein] synonym: "deep veins" RELATED [Wikipedia:Deep_vein] synonym: "deep vessels" RELATED [Wikipedia:Deep_vein] xref: FMA:76718 xref: NCIT:C32444 xref: SCTID:341484008 xref: UMLS:C0226514 xref: Wikipedia:Deep_vein is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0035551 ! deep vasculature relationship: part_of UBERON:0035551 ! deep vasculature [Term] id: UBERON:0035553 name: left cardiac chamber namespace: uberon def: "Any chamber of the left side of the heart." [http://orcid.org/0000-0002-6601-2165] xref: FMA:7166 xref: SCTID:362008007 is_a: UBERON:0004151 ! cardiac chamber is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0004151 ! cardiac chamber intersection_of: in_left_side_of UBERON:0000948 ! heart relationship: in_left_side_of UBERON:0000948 ! heart [Term] id: UBERON:0035554 name: right cardiac chamber namespace: uberon def: "Any chamber of the right side of the heart." [http://orcid.org/0000-0002-6601-2165] xref: FMA:7165 xref: SCTID:362007002 is_a: UBERON:0004151 ! cardiac chamber is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0004151 ! cardiac chamber intersection_of: in_right_side_of UBERON:0000948 ! heart relationship: in_right_side_of UBERON:0000948 ! heart [Term] id: UBERON:0035606 name: cartilage of external acoustic meatus namespace: uberon synonym: "cartilage of acoustic meatus" EXACT [FMA:61298] synonym: "cartilage of auditory canal" EXACT [FMA:61298] synonym: "cartilago meatus acustici" EXACT [FMA:TA] synonym: "external acoustic meatus cartilage" EXACT [FMA:61298] xref: FMA:61298 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0004121 ! ectoderm-derived structure is_a: UBERON:0034944 ! zone of organ intersection_of: UBERON:0034944 ! zone of organ intersection_of: part_of UBERON:0001352 ! external acoustic meatus intersection_of: part_of UBERON:0001867 ! cartilage of external ear relationship: part_of UBERON:0001352 ! external acoustic meatus relationship: part_of UBERON:0001867 ! cartilage of external ear [Term] id: UBERON:0035639 name: ocular adnexa namespace: uberon def: "The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva." [HPO:pr, http://medical-dictionary.thefreedictionary.com/ocular+adnexa, https://github.com/obophenotype/uberon/issues/1132, UBERON:cjm] synonym: "accessory parts of orbital region" RELATED [] synonym: "accessory visual structures" RELATED [FMA:76554, Wikipedia:Accessory_visual_structures] synonym: "accessory visual structures set" RELATED [FMA:76554] synonym: "adnexa oculi" EXACT LATIN [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "adnexal parts of orbital region" RELATED [] synonym: "appendage of eye" RELATED [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "appendages of the eye" RELATED PLURAL [http://medical-dictionary.thefreedictionary.com/ocular+adnexa] synonym: "eye adnexa" RELATED [] synonym: "set of accessory visual structures" RELATED [FMA:76554] synonym: "structurae oculi accessoriae" RELATED LATIN [Wikipedia:Accessory_visual_structures] xref: FMA:76554 xref: NCIT:C32574 xref: SCTID:120612006 xref: UMLS:C0229243 xref: Wikipedia:Accessory_visual_structures is_a: UBERON:0034921 ! multi organ part structure relationship: part_of UBERON:0004088 ! orbital region [Term] id: UBERON:0035642 name: laryngeal nerve namespace: uberon def: "Any nerve that innervates the larynx." [UBERON:cjm] xref: MESH:D007823 xref: SCTID:307013006 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0001737 ! larynx relationship: innervates UBERON:0001737 ! larynx [Term] id: UBERON:0035648 name: nerve innervating pinna namespace: uberon def: "Any nerve that innervates the pinna." [UBERON:cjm] synonym: "auricular nerve" EXACT [MA:0001232] xref: EMAPA:36513 xref: MA:0001232 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0011779 ! nerve of head region intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0001757 ! pinna relationship: branching_part_of UBERON:0001647 {source="FMA"} ! facial nerve relationship: innervates UBERON:0001757 ! pinna relationship: part_of UBERON:0001647 ! facial nerve [Term] id: UBERON:0035649 name: nerve of penis namespace: uberon def: "Any nerve that innervates the penis." [UBERON:cjm] synonym: "penile nerve" EXACT [] synonym: "penis nerve" EXACT [] xref: EMAPA:35057 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0000989 ! penis relationship: innervates UBERON:0000989 ! penis [Term] id: UBERON:0035650 name: nerve of clitoris namespace: uberon def: "Any nerve that innervates the clitoris." [UBERON:cjm] synonym: "clitoral nerve" EXACT [] synonym: "clitoris nerve" EXACT [] xref: EMAPA:35044 is_a: CARO:0001001 ! neuron projection bundle is_a: UBERON:0001021 ! nerve intersection_of: UBERON:0001021 ! nerve intersection_of: innervates UBERON:0002411 ! clitoris relationship: innervates UBERON:0002411 ! clitoris [Term] id: UBERON:0035651 name: glans namespace: uberon xref: Wikipedia:Glans is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure union_of: UBERON:0001299 ! glans penis union_of: UBERON:0006653 ! glans clitoris relationship: develops_from UBERON:0013238 ! future glans relationship: part_of UBERON:0003133 ! reproductive organ [Term] id: UBERON:0035763 name: cavity of cardiac chamber namespace: uberon synonym: "cardiac chamber cavity" EXACT [FMA:9464] synonym: "heart cavity" EXACT [FMA:9464] synonym: "heart lumen" EXACT [EHDAA2:0004181] xref: EHDAA2:0004181 xref: FMA:9464 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0004151 ! cardiac chamber relationship: luminal_space_of UBERON:0004151 ! cardiac chamber relationship: part_of UBERON:0004151 ! cardiac chamber relationship: surrounded_by UBERON:0002165 {source="FMA"} ! endocardium [Term] id: UBERON:0035767 name: intrapulmonary bronchus namespace: uberon subset: human_reference_atlas xref: FMA:223208 xref: NCIT:C12930 xref: UMLS:C1512970 is_a: UBERON:0002185 ! bronchus intersection_of: UBERON:0002185 ! bronchus intersection_of: part_of UBERON:0002048 ! lung relationship: part_of UBERON:0002048 ! lung property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0035804 name: future mouth namespace: uberon def: "The primordial mouth region of the developing head." [MP:0003119] synonym: "primitive mouth" EXACT [FMA:293105] synonym: "primordial mouth" EXACT [] xref: FMA:293105 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0013522 ! subdivision of tube relationship: has_part UBERON:0000925 ! endoderm relationship: has_part UBERON:0000930 ! stomodeum relationship: part_of UBERON:0007026 ! presumptive gut [Term] id: UBERON:0035805 name: muscle layer of sigmoid colon namespace: uberon def: "A muscle layer that is part of the sigmoid colon." [https://github.com/obophenotype/uberon/issues/1162] synonym: "muscularis externa of sigmoid colon" EXACT [FMA:15028] synonym: "muscularis propria of sigmoid colon" EXACT [] synonym: "sigmoid colon muscularis propria" EXACT [] synonym: "sigmoideum muscularis" RELATED [] synonym: "tunica muscularis colon sigmoideum" RELATED [] xref: FMA:15028 is_a: UBERON:0012489 ! muscle layer of colon intersection_of: UBERON:0006660 ! muscular coat intersection_of: part_of UBERON:0001159 ! sigmoid colon relationship: part_of UBERON:0001159 ! sigmoid colon [Term] id: UBERON:0035809 name: serous cavity namespace: uberon xref: FMA:12241 xref: SCTID:304404008 is_a: UBERON:0002553 ! anatomical cavity intersection_of: UBERON:0002553 ! anatomical cavity intersection_of: luminal_space_of UBERON:0005906 ! serous sac relationship: luminal_space_of UBERON:0005906 ! serous sac relationship: part_of UBERON:0005906 ! serous sac [Term] id: UBERON:0035814 name: pericardial fat namespace: uberon def: "The sum of epicardial and paracardial fat deposits." [DOI:10.5935/abc.20130138] xref: SCTID:42267001 xref: ZFA:0005765 is_a: UBERON:0035818 ! visceral fat intersection_of: UBERON:0001013 ! adipose tissue intersection_of: surrounds UBERON:0000948 ! heart relationship: surrounds UBERON:0000948 ! heart [Term] id: UBERON:0035815 name: paracardial fat namespace: uberon def: "Fat deposits in the mediastinum outside the parietal pericardium ." [DOI:10.5935/abc.20130138] synonym: "intrathoracic fat" EXACT [DOI:10.5935/abc.20130138] is_a: UBERON:0035814 ! pericardial fat intersection_of: UBERON:0001013 ! adipose tissue intersection_of: adjacent_to UBERON:0002408 ! parietal serous pericardium intersection_of: surrounds UBERON:0000948 ! heart relationship: adjacent_to UBERON:0002408 ! parietal serous pericardium [Term] id: UBERON:0035818 name: visceral fat namespace: uberon def: "Any fat deposit surrounding a visceral organ." [UBERON:cjm] is_a: UBERON:0001013 ! adipose tissue intersection_of: UBERON:0001013 ! adipose tissue intersection_of: surrounds UBERON:0000062 ! organ relationship: surrounds UBERON:0000062 ! organ [Term] id: UBERON:0035819 name: abdominopelvic cavity namespace: uberon def: "The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity." [UBERON:cjm] synonym: "cavitas abdominis et pelvis" EXACT LATIN [FMA:TA] xref: FMA:12267 xref: Wikipedia:Abdominopelvic_cavity is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0002417 ! abdominal segment of trunk intersection_of: part_of UBERON:0002323 ! coelemic cavity lumen relationship: luminal_space_of UBERON:0002417 ! abdominal segment of trunk relationship: part_of UBERON:0002323 ! coelemic cavity lumen relationship: part_of UBERON:0002417 ! abdominal segment of trunk [Term] id: UBERON:0035820 name: peritoneal sac namespace: uberon def: "A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity." [https://github.com/obophenotype/uberon/issues/86] synonym: "peritoneal component" RELATED [EMAPA:16137] xref: EMAPA:16137 xref: FMA:9908 is_a: UBERON:0002075 ! viscus is_a: UBERON:0005906 ! serous sac relationship: has_part UBERON:0001179 ! peritoneal cavity relationship: has_part UBERON:0002358 ! peritoneum relationship: located_in UBERON:0003684 ! abdominal cavity [Term] id: UBERON:0035831 name: costal diaphragm namespace: uberon def: "The domain of the diaphragm that is a thin domed sheet of muscle composed of a radial array of myofibers extending laterally from the ribs and medially to a central tendon." [PMID:23586979] synonym: "costal part of diaphragm" EXACT [FMA:58277] synonym: "pars costalis diaphragmatis" EXACT LATIN [FMA:TA] xref: FMA:58277 xref: SCTID:368048007 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000063 ! organ subunit is_a: UBERON:0015212 ! lateral structure relationship: attaches_to UBERON:0006670 ! central tendon of diaphragm relationship: in_lateral_side_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm relationship: part_of UBERON:0001103 {source="PMID:23586979"} ! diaphragm [Term] id: UBERON:0035881 name: ethmoidomaxillary suture namespace: uberon def: "A suture between the orbital surface of the body of the maxilla with the orbital plate of the ethmoid bone." [http://medical-dictionary.thefreedictionary.com/ethmoidomaxillary+suture] synonym: "ethmoidomaxillary suture of skull" EXACT [FMA:52954] synonym: "sutura ethmoidomaxillaris" EXACT LATIN [FMA:TA] xref: FMA:52954 is_a: UBERON:0003685 ! cranial suture intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0001679 ! ethmoid bone intersection_of: connects UBERON:0002397 ! maxilla relationship: connects UBERON:0001679 ! ethmoid bone relationship: connects UBERON:0002397 ! maxilla [Term] id: UBERON:0035884 name: maxillary-premaxillary suture namespace: uberon def: "A suture between the maxilla and premaxilla." [https://github.com/obophenotype/mammalian-phenotype-ontology/issues/2139, MGI:csmith, PMID:21538817] synonym: "incisive suture" RELATED [MGI:csmith] synonym: "maxillary-premaxillary incisive suture" EXACT [UBERON:cjm] synonym: "premaxillary suture" RELATED [MGI:csmith] is_a: UBERON:0003685 ! cranial suture is_a: UBERON:2002260 ! premaxillary-maxillary joint intersection_of: UBERON:0003685 ! cranial suture intersection_of: connects UBERON:0002244 ! premaxilla intersection_of: connects UBERON:0002397 ! maxilla property_value: UBPROP:0000008 "present in mouse [PMID:21538817]" xsd:string property_value: UBPROP:0000008 "transient in humans" xsd:string [Term] id: UBERON:0035956 name: epididymal lumen namespace: uberon def: "The lumen of the epididymis." [GOC:DOS, https://github.com/obophenotype/uberon/issues/1209] synonym: "epididymis lumen" EXACT [FMA:18274] synonym: "lumen of epididymis" EXACT [FMA:18274] xref: FMA:18274 xref: SCTID:367722009 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000464 ! anatomical space intersection_of: UBERON:0000464 ! anatomical space intersection_of: luminal_space_of UBERON:0001301 ! epididymis relationship: contains UBERON:0006530 {source="FMA"} ! seminal fluid relationship: luminal_space_of UBERON:0001301 ! epididymis relationship: part_of UBERON:0001301 ! epididymis [Term] id: UBERON:0035965 name: wall of blood vessel namespace: uberon synonym: "blood vessel wall" EXACT [FMA:67473] synonym: "vascular wall" RELATED [BTO:0004378] xref: BTO:0004378 xref: EMAPA:37987 {source="MA:th"} xref: FMA:67473 is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001981 ! blood vessel relationship: composed_primarily_of UBERON:0004797 ! blood vessel layer relationship: part_of UBERON:0001981 ! blood vessel [Term] id: UBERON:0036072 name: respiratory primordium epithelium namespace: uberon xref: EHDAA2:0004070 is_a: UBERON:0004185 ! endodermal part of digestive tract is_a: UBERON:0005911 ! endo-epithelium is_a: UBERON:0007499 ! epithelial sac is_a: UBERON:0009854 ! digestive tract diverticulum is_a: UBERON:0015833 ! foregut epithelium intersection_of: UBERON:0007499 ! epithelial sac intersection_of: part_of UBERON:0008947 ! respiratory primordium relationship: develops_from UBERON:0007690 {source="EHDAA2"} ! early pharyngeal endoderm relationship: part_of UBERON:0008947 ! respiratory primordium [Term] id: UBERON:0036073 name: respiratory primordium mesenchyme namespace: uberon synonym: "respiratory primordium associated mesenchyme" EXACT [EHDAA2:0004071] xref: EHDAA2:0004071 is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure is_a: UBERON:0003104 ! mesenchyme intersection_of: UBERON:0003104 ! mesenchyme intersection_of: part_of UBERON:0008947 ! respiratory primordium relationship: develops_from UBERON:0004873 {source="EHDAA2"} ! splanchnopleure relationship: part_of UBERON:0008947 ! respiratory primordium [Term] id: UBERON:0036146 name: cardiopharyngeal field namespace: uberon def: "An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles." [http://www.nature.com/nature/journal/v520/n7548/full/nature14435.html#bx1, https://orcid.org/0000-0003-3308-6245] is_a: UBERON:0002050 ! embryonic structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005291 ! embryonic tissue is_a: UBERON:0007688 ! anlage [Term] id: UBERON:0036186 name: fibroelastic connective tissue namespace: uberon xref: FMA:83520 is_a: UBERON:0002521 ! elastic tissue is_a: UBERON:0011824 ! fibrous connective tissue intersection_of: UBERON:0011824 ! fibrous connective tissue intersection_of: composed_primarily_of GO:0071953 ! elastic fiber [Term] id: UBERON:0036212 name: intertragic incisure namespace: uberon def: "A surface structure that is the narrowed downward continuation of the conchal space bounded anteriorly by the borders of the tragus, posteriorly by theantitragus, and along its lower lateral margins and inferior boundary by the connection between the first two." [https://github.com/obophenotype/human-phenotype-ontology/issues/2274, PMID:20082456, UBERON:cjm, Wikipedia:Incisura_anterior_auris] comment: Measurement notes: The length is measured from the upper to the lower border (between tragus and antitragus) synonym: "anterior auricular groove" RELATED [Wikipedia:Incisura_anterior_auris] synonym: "auricular notch" RELATED [Wikipedia:Incisura_anterior_auris] synonym: "incisura" BROAD [https://github.com/obophenotype/human-phenotype-ontology/issues/2274] synonym: "incisura anterior auris" RELATED [Wikipedia:Incisura_anterior_auris] synonym: "incisura intertragica" EXACT LATIN [FMA:TA] synonym: "intertragal incisure" EXACT [FMA:61175] synonym: "intertragic incisure" EXACT [FMA:61175] synonym: "intertragic incisure" RELATED [Wikipedia:Incisura_anterior_auris] synonym: "intertragic notch" EXACT [FMA:61175] synonym: "sulcus auriculae anterior" RELATED [Wikipedia:Incisura_anterior_auris] xref: FMA:61175 xref: SCTID:362542005 xref: Wikipedia:Incisura_anterior_auris is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006846 ! surface groove intersection_of: UBERON:0006846 ! surface groove intersection_of: adjacent_to UBERON:0010887 ! tragus intersection_of: adjacent_to UBERON:0016467 ! antitragus intersection_of: part_of UBERON:0001757 ! pinna relationship: adjacent_to UBERON:0010887 ! tragus relationship: adjacent_to UBERON:0016467 ! antitragus relationship: part_of UBERON:0001757 ! pinna [Term] id: UBERON:0036214 name: rectosigmoid junction namespace: uberon def: "An anatomical junction that is between the sigmoid colon and rectum." [https://github.com/obophenotype/uberon/issues/1319, https://www.cdc.gov/cancer/npcr/pdf/abstracting/colon.pdf, NCIT:C54188] synonym: "rectosigmoid region" RELATED [NCIT:C54188] xref: NCIT:C54188 xref: SCTID:245429006 is_a: UBERON:8410024 ! intestinal junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0001052 ! rectum intersection_of: connects UBERON:0001159 ! sigmoid colon relationship: connects UBERON:0001052 ! rectum relationship: connects UBERON:0001159 ! sigmoid colon [Term] id: UBERON:0036215 name: anatomical surface region namespace: uberon def: "Material anatomical entity that forms the outermost boundary of an anatomical structure." [https://github.com/obophenotype/uberon/issues/1324] subset: common_anatomy xref: AAO:0010270 xref: AEO:0000154 xref: ZFA:0005594 is_a: UBERON:0000465 ! material anatomical entity relationship: bounding_layer_of UBERON:0000061 ! anatomical structure relationship: part_of UBERON:0000061 ! anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0036217 name: coelomic fluid namespace: uberon def: "A bodily fluid that is located in the coelom." [https://github.com/obophenotype/uberon/issues/1326, PMID:10874572] xref: BTO:0001708 is_a: UBERON:0006314 ! bodily fluid intersection_of: UBERON:0006314 ! bodily fluid intersection_of: located_in UBERON:0011997 ! coelom relationship: located_in UBERON:0011997 ! coelom property_value: UBPROP:0000009 "he coelomic fluid serves several functions; it acts as a hydroskeleton, it allows free movement and growth of internal organs, it serves for transport of gases, nutrients and waste products between different parts of the body, it allows storage of sperm and eggs during maturation and it acts as a reservoir for waste [Wikipedia:Coelom#Coelomic_fluid]" xsd:string [Term] id: UBERON:0036225 name: respiratory system gland namespace: uberon def: "Any gland that is part os the respiratory system." [UBERON:cjm] is_a: UBERON:0002530 ! gland intersection_of: UBERON:0002530 ! gland intersection_of: part_of UBERON:0001004 ! respiratory system relationship: part_of UBERON:0001004 ! respiratory system [Term] id: UBERON:0036242 name: post-embryonic notochord namespace: uberon def: "A notochord that has persisted beyond the embryonic stage." [UBERON:cjm] is_a: UBERON:0002328 ! notochord intersection_of: UBERON:0002328 ! notochord intersection_of: part_of UBERON:0009953 ! post-embryonic organism relationship: part_of UBERON:0009953 ! post-embryonic organism property_value: RO:0002161 NCBITaxon:32524 property_value: RO:0002175 NCBITaxon:118072 property_value: RO:0002175 NCBITaxon:7737 property_value: RO:0002175 NCBITaxon:7746 property_value: RO:0002175 NCBITaxon:7878 property_value: RO:0002175 NCBITaxon:8292 [Term] id: UBERON:0036244 name: secretion of serous membrane namespace: uberon def: "A transudate found in the serous sac." [FMA:20932] synonym: "serous fluid" BROAD [FMA:20932] synonym: "serous sac fluid" EXACT [] xref: FMA:20932 is_a: UBERON:0007779 ! transudate intersection_of: UBERON:0007779 ! transudate intersection_of: filtered_through UBERON:0000042 ! serous membrane relationship: filtered_through UBERON:0000042 ! serous membrane relationship: located_in UBERON:0005906 ! serous sac [Term] id: UBERON:0036248 name: joint of auditory ossicle namespace: uberon def: "Any synovial joint that connects auditory ossicles." [UBERON:cjm] synonym: "auditory ossicle joint" EXACT [] synonym: "auditory ossicles joint" EXACT [FMA:60063] synonym: "joint of auditory ossicles" EXACT [FMA:60063] xref: FMA:60063 is_a: UBERON:0002217 ! synovial joint intersection_of: UBERON:0002217 ! synovial joint intersection_of: connects UBERON:0035130 ! auditory ossicle endochondral element relationship: connects UBERON:0035130 ! auditory ossicle endochondral element relationship: part_of UBERON:0000033 ! head [Term] id: UBERON:0036253 name: orifice of skull namespace: uberon synonym: "cranial orifice" EXACT [FMA:53133] synonym: "skull orifice" EXACT [FMA:53133] xref: FMA:53133 is_a: UBERON:0000161 ! orifice intersection_of: UBERON:0000161 ! orifice intersection_of: part_of UBERON:0003129 ! skull relationship: part_of UBERON:0003129 ! skull [Term] id: UBERON:0036264 name: zygomaticotemporal nerve namespace: uberon def: "The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit." [Wikipedia:Zygomaticotemporal_nerve] synonym: "ramus zygomaticotemporalis (Nervus zygomaticus)" EXACT [FMA:52972] synonym: "ramus zygomaticotemporalis nervus zygomatici" EXACT LATIN [FMA:TA] synonym: "zygomaticotemporal" RELATED [Wikipedia:Zygomaticotemporal_nerve] synonym: "zygomaticotemporal branch" RELATED [Wikipedia:Zygomaticotemporal_nerve] synonym: "zygomaticotemporal branch of zygomatic nerve" EXACT [FMA:52972] xref: FMA:52972 xref: SCTID:280243001 xref: Wikipedia:Zygomaticotemporal_nerve is_a: UBERON:0011779 ! nerve of head region relationship: branching_part_of UBERON:0000377 ! maxillary nerve relationship: part_of UBERON:0000377 ! maxillary nerve [Term] id: UBERON:0036267 name: vulval vein namespace: uberon xref: SCTID:279975006 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0000997 ! mammalian vulva relationship: drains UBERON:0000997 ! mammalian vulva relationship: part_of RO:0002577 ! system [Term] id: UBERON:0036268 name: pelvic vein namespace: uberon xref: SCTID:13152008 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0002355 ! pelvic region of trunk relationship: drains UBERON:0002355 ! pelvic region of trunk relationship: part_of RO:0002577 ! system [Term] id: UBERON:0036269 name: penis blood vessel namespace: uberon synonym: "penis vasculature" RELATED [] synonym: "vasculature of penis" RELATED [EMAPA:30807] xref: EMAPA:30807 xref: SCTID:363673006 is_a: UBERON:0001981 ! blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: connected_to UBERON:0000989 ! penis relationship: connected_to UBERON:0000989 ! penis relationship: part_of RO:0002577 ! system [Term] id: UBERON:0036285 name: wall of left ventricle namespace: uberon def: "Wall of ventricle which is continuous with the wall of aorta." [FMA:9556] synonym: "left ventricular wall" EXACT [FMA:9556] xref: FMA:9556 is_a: UBERON:0004784 {source="FMA"} ! heart ventricle wall intersection_of: UBERON:0004784 ! heart ventricle wall intersection_of: part_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0002084 {source="FMA"} ! heart left ventricle [Term] id: UBERON:0036286 name: wall of right ventricle namespace: uberon def: "Wall of ventricle which is continuous with the wall of pulmonary trunk." [FMA:9533] synonym: "right ventricular wall" EXACT [FMA:9533] xref: FMA:9533 is_a: UBERON:0004784 {source="FMA"} ! heart ventricle wall intersection_of: UBERON:0004784 ! heart ventricle wall intersection_of: part_of UBERON:0002080 ! heart right ventricle relationship: part_of UBERON:0002080 {source="FMA"} ! heart right ventricle [Term] id: UBERON:0036288 name: anterior wall of left ventricle namespace: uberon xref: FMA:9560 is_a: UBERON:0036285 ! wall of left ventricle intersection_of: UBERON:0004784 ! heart ventricle wall intersection_of: in_anterior_side_of UBERON:0002084 ! heart left ventricle relationship: in_anterior_side_of UBERON:0002084 ! heart left ventricle relationship: part_of UBERON:0036285 {source="FMA"} ! wall of left ventricle [Term] id: UBERON:0036289 name: anterior wall of right ventricle namespace: uberon def: "Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle." [FMA:9553] xref: FMA:9553 is_a: UBERON:0036286 ! wall of right ventricle intersection_of: UBERON:0004784 ! heart ventricle wall intersection_of: in_anterior_side_of UBERON:0002080 ! heart right ventricle relationship: in_anterior_side_of UBERON:0002080 ! heart right ventricle [Term] id: UBERON:0036290 name: myocardium of anterior wall of left ventricle namespace: uberon xref: FMA:87177 is_a: UBERON:0006566 ! left ventricle myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0036288 ! anterior wall of left ventricle relationship: part_of UBERON:0036288 ! anterior wall of left ventricle [Term] id: UBERON:0036291 name: myocardium of anterior wall of right ventricle namespace: uberon xref: FMA:260877 is_a: UBERON:0006567 ! right ventricle myocardium intersection_of: UBERON:0002349 ! myocardium intersection_of: part_of UBERON:0036289 ! anterior wall of right ventricle relationship: part_of UBERON:0036289 ! anterior wall of right ventricle [Term] id: UBERON:0036294 name: mucosa of lip namespace: uberon def: "A mucosa that is part of a lip region [Automatically generated definition]." [OBOL:automatic] synonym: "labial mucosa" EXACT [UBERON:cjm] xref: NCIT:C12226 is_a: UBERON:0003729 ! mouth mucosa intersection_of: UBERON:0000344 ! mucosa intersection_of: part_of UBERON:0001833 ! lip relationship: part_of UBERON:0001833 ! lip [Term] id: UBERON:0036295 name: renal pelvis/ureter namespace: uberon def: "The upper tract of the renal system. The renal pelvis is the large cavity in the middle of each kidney. Urine drains from each kidney through a long tube called the ureter, into the bladder, where it is stored until it is passed from the body through the urethra." [NCIT:C54419] synonym: "renal pelvis and ureter" EXACT [] synonym: "renal pelvis plus ureter" EXACT [] xref: NCIT:C54419 is_a: UBERON:0000477 ! anatomical cluster relationship: part_of UBERON:0011143 {source="NCIT"} ! upper urinary tract [Term] id: UBERON:0036301 name: vasculature of spleen namespace: uberon xref: FMA:225251 xref: SCTID:297287005 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0002201 ! vasculature of trunk is_a: UBERON:0006876 {source="FMA"} ! vasculature of organ intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0002106 ! spleen [Term] id: UBERON:0036302 name: vasculature of central nervous system plus retina namespace: uberon is_a: UBERON:0002049 ! vasculature union_of: UBERON:0004864 ! vasculature of retina union_of: UBERON:0036303 ! vasculature of central nervous system [Term] id: UBERON:0036303 name: vasculature of central nervous system namespace: uberon xref: FMA:259905 is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0036302 ! vasculature of central nervous system plus retina intersection_of: UBERON:0002049 ! vasculature intersection_of: part_of UBERON:0001017 ! central nervous system relationship: part_of UBERON:0001017 ! central nervous system [Term] id: UBERON:0036304 name: anatomical border namespace: uberon def: "An anatomical structure that is located along the line dividing two regions of an anatomical structure." [UBERON:cjm] subset: common_anatomy is_a: UBERON:0000061 ! anatomical structure property_value: RO:0002175 NCBITaxon:33090 property_value: RO:0002175 NCBITaxon:33208 property_value: RO:0002175 NCBITaxon:4751 [Term] id: UBERON:0036343 name: wall of gallbladder namespace: uberon synonym: "gallbladder wall" EXACT [FMA:14657] xref: FMA:14657 is_a: UBERON:0003697 ! abdominal wall is_a: UBERON:0004119 ! endoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0002110 ! gallbladder relationship: part_of UBERON:0002110 {source="FMA"} ! gallbladder [Term] id: UBERON:0036351 name: wall of brachiocephalic artery namespace: uberon synonym: "brachiocephalic arterial wall" EXACT [FMA:15089] xref: FMA:15089 is_a: UBERON:0000415 {source="FMA"} ! artery wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001529 ! brachiocephalic artery relationship: part_of UBERON:0001529 {source="FMA"} ! brachiocephalic artery [Term] id: UBERON:0036352 name: wall of subclavian artery namespace: uberon synonym: "subclavian arterial wall" EXACT [FMA:15090] xref: FMA:15090 is_a: UBERON:0000415 {source="FMA"} ! artery wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001533 ! subclavian artery relationship: part_of UBERON:0001533 {source="FMA"} ! subclavian artery [Term] id: UBERON:0036362 name: wall of anal canal namespace: uberon synonym: "anal canal wall" EXACT [FMA:15704] xref: FMA:15704 is_a: UBERON:0001169 ! wall of large intestine is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000159 ! anal canal intersection_of: part_of UBERON:0001007 ! digestive system relationship: part_of UBERON:0000159 {source="FMA"} ! anal canal [Term] id: UBERON:0036375 name: wall of right ureter namespace: uberon synonym: "right ureteral wall" EXACT [FMA:15889] xref: FMA:15889 is_a: UBERON:0009916 {source="FMA"} ! wall of ureter intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001222 ! right ureter relationship: part_of UBERON:0001222 {source="FMA"} ! right ureter [Term] id: UBERON:0036376 name: wall of left ureter namespace: uberon subset: human_reference_atlas synonym: "left ureteral wall" EXACT [FMA:15890] xref: FMA:15890 is_a: UBERON:0009916 {source="FMA"} ! wall of ureter intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001223 ! left ureter relationship: part_of UBERON:0001223 {source="FMA"} ! left ureter property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0036422 name: wall of pulmonary artery namespace: uberon subset: human_reference_atlas synonym: "pulmonary arterial wall" EXACT [FMA:18211] xref: FMA:18211 is_a: UBERON:0000415 {source="FMA"} ! artery wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0002012 ! pulmonary artery relationship: part_of UBERON:0002012 {source="FMA"} ! pulmonary artery property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:0036441 name: wall of uterine tube namespace: uberon synonym: "uterine tube wall" EXACT [FMA:18303] synonym: "wall of fallopian tube" EXACT [FMA:18303] synonym: "wall of oviduct" EXACT [FMA:18303] xref: FMA:18303 is_a: UBERON:0000060 {source="FMA"} ! anatomical wall is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: part_of UBERON:0003889 {source="FMA"} ! fallopian tube [Term] id: UBERON:0036521 name: wall of urethra namespace: uberon synonym: "urethral wall" EXACT [FMA:19779] xref: FMA:19779 is_a: UBERON:0000060 {source="FMA"} ! anatomical wall is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000057 ! urethra relationship: part_of UBERON:0000057 {source="FMA"} ! urethra [Term] id: UBERON:0036553 name: wall of synovial tendon sheath namespace: uberon xref: FMA:231590 is_a: UBERON:0000042 {source="FMA"} ! serous membrane is_a: UBERON:0000060 ! anatomical wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000304 ! tendon sheath relationship: part_of UBERON:0000304 {source="FMA"} ! tendon sheath [Term] id: UBERON:0036925 name: wall of eyeball namespace: uberon synonym: "eyeball wall" EXACT [FMA:58098] xref: FMA:58098 is_a: UBERON:0000060 {source="FMA"} ! anatomical wall is_a: UBERON:0004121 ! ectoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0010230 ! eyeball of camera-type eye relationship: part_of UBERON:0010230 {source="FMA"} ! eyeball of camera-type eye [Term] id: UBERON:0037089 name: wall of orbit namespace: uberon synonym: "orbit wall" EXACT [FMA:63144] xref: FMA:63144 is_a: UBERON:0000060 ! anatomical wall is_a: UBERON:0000075 {source="FMA"} ! subdivision of skeletal system is_a: UBERON:0010313 ! neural crest-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001697 ! orbit of skull relationship: part_of UBERON:0001697 {source="FMA"} ! orbit of skull [Term] id: UBERON:0037094 name: wall of common carotid artery namespace: uberon synonym: "common carotid arterial wall" EXACT [FMA:66284] xref: FMA:66284 is_a: UBERON:0000415 {source="FMA"} ! artery wall intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001530 ! common carotid artery plus branches relationship: part_of UBERON:0001530 {source="FMA"} ! common carotid artery plus branches [Term] id: UBERON:0037144 name: wall of heart namespace: uberon def: "Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees." [FMA:7274] synonym: "cardiac wall" EXACT [FMA:7274] xref: FMA:7274 is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000060 {source="FMA"} ! anatomical wall is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0000948 ! heart relationship: attaches_to UBERON:0002406 {source="FMA"} ! pericardial sac relationship: attaches_to UBERON:0004292 {source="FMA"} ! cardiac skeleton relationship: part_of RO:0002577 ! system relationship: part_of UBERON:0000948 {source="FMA"} ! heart [Term] id: UBERON:0037447 name: wall of male urethra namespace: uberon synonym: "male urethral wall" EXACT [FMA:19676] xref: FMA:19676 is_a: UBERON:0036521 {source="FMA"} ! wall of urethra intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001333 ! male urethra relationship: part_of UBERON:0001333 {source="FMA"} ! male urethra [Term] id: UBERON:0037455 name: wall of female urethra namespace: uberon synonym: "female urethral wall" EXACT [FMA:19780] xref: FMA:19780 is_a: UBERON:0036521 {source="FMA"} ! wall of urethra intersection_of: UBERON:0000060 ! anatomical wall intersection_of: part_of UBERON:0001334 ! female urethra relationship: part_of UBERON:0001334 {source="FMA"} ! female urethra [Term] id: UBERON:0039222 name: cystic artery namespace: uberon def: "An artery that supplies oxygenated blood to the cystic duct." [http://orcid.org/0000-0002-6601-2165, https://en.wikipedia.org/wiki/Cystic_artery] synonym: "cholecystic artery" EXACT [FMA:14835] xref: FMA:14835 is_a: UBERON:0001637 ! artery is_a: UBERON:0015796 ! liver blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001152 ! cystic duct relationship: part_of UBERON:0015482 {source="FMA", source="Wikipedia"} ! right hepatic artery relationship: supplies UBERON:0001152 ! cystic duct [Term] id: UBERON:0039228 name: sigmoid vein namespace: uberon xref: FMA:15395 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0001159 ! sigmoid colon relationship: drains UBERON:0001159 ! sigmoid colon relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0001215 {source="FMA"} ! inferior mesenteric vein [Term] id: UBERON:0039261 name: pancreatic artery namespace: uberon xref: FMA:70471 is_a: UBERON:0004573 ! systemic artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0001264 ! pancreas relationship: branching_part_of UBERON:0001194 ! splenic artery relationship: part_of UBERON:0001194 ! splenic artery relationship: supplies UBERON:0001264 ! pancreas [Term] id: UBERON:0039355 name: urethral artery namespace: uberon synonym: "arteria urethralis" EXACT LATIN [A12.2.15.042] xref: FMA:20903 is_a: UBERON:0001637 ! artery intersection_of: UBERON:0001637 ! artery intersection_of: supplies UBERON:0000057 ! urethra relationship: part_of RO:0002577 ! system relationship: supplies UBERON:0000057 ! urethra [Term] id: UBERON:0039377 name: urethral vein namespace: uberon def: "A vein that drains the urethra." [UBERON:cjm] xref: FMA:21270 is_a: UBERON:0001638 ! vein intersection_of: UBERON:0001638 ! vein intersection_of: drains UBERON:0000057 ! urethra relationship: drains UBERON:0000057 ! urethra relationship: part_of RO:0002577 ! system relationship: tributary_of UBERON:0018252 {source="FMA"} ! internal pudendal vein [Term] id: UBERON:0039856 name: right ovarian vein namespace: uberon def: "Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament." [FMA:14342] xref: FMA:14342 is_a: UBERON:0001145 {source="FMA"} ! ovarian vein intersection_of: UBERON:0001145 ! ovarian vein intersection_of: drains UBERON:0002118 ! right ovary relationship: drains UBERON:0002118 ! right ovary relationship: tributary_of UBERON:0001072 {source="FMA"} ! posterior vena cava [Term] id: UBERON:0039857 name: left ovarian vein namespace: uberon def: "Ovarian vein, each instance of which is a tributary of some left renal vein that drains the left pampiniform plexus of some broad ligament." [FMA:14347] xref: FMA:14347 is_a: UBERON:0001145 {source="FMA"} ! ovarian vein intersection_of: UBERON:0001145 ! ovarian vein intersection_of: drains UBERON:0002119 ! left ovary relationship: drains UBERON:0002119 ! left ovary [Term] id: UBERON:1000015 name: skin of snout namespace: uberon def: "A zone of skin that is part of the snout." [https://github.com/obophenotype/uberon/issues/34, UBERON:EJS] subset: phenotype_rcn synonym: "snout skin" EXACT [MA:0003079] xref: EMAPA:37746 {source="MA:th"} xref: MA:0003079 is_a: UBERON:1000021 ! skin of face intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0006333 ! snout relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/seger relationship: part_of UBERON:0006333 ! snout [Term] id: UBERON:1000016 name: tip of snout namespace: uberon def: "Subdivision of the head consisting of the pointed or rounded end or extremity of the snout." [https://github.com/obophenotype/uberon/issues/34, UBERON:EJS] subset: phenotype_rcn is_a: UBERON:0034929 ! external soft tissue zone relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/seger relationship: part_of UBERON:0006333 ! snout [Term] id: UBERON:1000021 name: skin of face namespace: uberon def: "A zone of skin that is part of the face." [https://github.com/obophenotype/uberon/issues/34, UBERON:EJS] subset: pheno_slim subset: phenotype_rcn synonym: "face skin" EXACT [EMAPA:36657, FMA:24758] synonym: "facial skin" RELATED [] xref: EMAPA:36657 xref: FMA:24758 xref: NCIT:C33561 xref: SCTID:361703006 xref: UMLS:C0222084 {source="ncithesaurus:Skin_of_the_Face"} is_a: UBERON:0001084 ! skin of head intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001456 ! face relationship: dc-contributor https://orcid.org/0000-0002-9611-1279 relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/cmungall relationship: http://purl.org/dc/elements/1.1/contributor https://github.com/seger relationship: part_of UBERON:0001456 ! face creation_date: 2012-02-05T05:23:01Z [Term] id: UBERON:1000024 name: parenchyma of spleen namespace: uberon def: "A parenchyma that is part of a spleen." [OBOL:automatic] synonym: "splenic parenchyma" EXACT [FMA:16029] xref: FMA:16029 is_a: UBERON:0000353 ! parenchyma is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000353 ! parenchyma intersection_of: part_of UBERON:0002106 ! spleen relationship: part_of UBERON:0002106 ! spleen [Term] id: UBERON:1100000 name: digestive tract junction namespace: uberon def: "An anatomical junction between two parts of the digestive tract." [https://orcid.org/0000-0002-7073-9172] is_a: UBERON:0007651 ! anatomical junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0004921 ! subdivision of digestive tract relationship: connects UBERON:0004921 ! subdivision of digestive tract relationship: dc-contributor https://orcid.org/0000-0002-7073-9172 creation_date: 2021-02-05T11:19:31Z [Term] id: UBERON:2001053 name: future internal carotid artery namespace: uberon synonym: "PICA" EXACT [TAO:0001053] synonym: "primitive internal carotid artery" EXACT [ZFA:0001053] xref: EFO:0003612 xref: TAO:0001053 xref: ZFA:0001053 is_a: UBERON:0004573 ! systemic artery relationship: develops_from UBERON:0003120 {gci_relation="part_of", gci_filler="NCBITaxon:40674", source="EHDAA2"} ! pharyngeal arch artery 3 relationship: develops_from UBERON:0004363 ! pharyngeal arch artery relationship: part_of UBERON:0001530 {source="EHDAA2"} ! common carotid artery plus branches [Term] id: UBERON:2001073 name: axial vasculature namespace: uberon xref: ZFA:0001073 is_a: UBERON:0002049 ! vasculature property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2001457 name: postcranial axial cartilage namespace: uberon def: "Cartilage which is part of the axial skeleton." [ZFIN:curator] xref: ZFA:0001457 is_a: UBERON:0007844 ! cartilage element intersection_of: UBERON:0007844 ! cartilage element intersection_of: part_of UBERON:0002090 ! postcranial axial skeleton relationship: part_of UBERON:0002090 ! postcranial axial skeleton property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2001626 name: premaxillary tooth namespace: uberon def: "Tooth that is attached to the premaxilla." [TAO:wd] is_a: UBERON:0003267 ! tooth of upper jaw intersection_of: UBERON:0001091 ! calcareous tooth intersection_of: attaches_to UBERON:0002244 ! premaxilla relationship: attaches_to UBERON:0002244 ! premaxilla property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2001783 name: supraoccipital crest namespace: uberon def: "Process that is part of the supraoccipital. It is a posteriorly directed and unpaired median projection off the posterior margin of the supraoccipital bone." [TAO:GA_TG] comment: The supraoccipital crest may be small and restricted to the dorsal part of the supraoccipital, or may be large and long and extending ventrally to the dorsal margin of the foramen magnum. The supraoccipital crest may be a large process extending above the skull roof in some teleostean subgroups. synonym: "supraoccipital process" EXACT [TAO:0001783] synonym: "supraoccipital spine" EXACT [TAO:0001783] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4100000 ! skeletal element projection relationship: part_of UBERON:0004747 ! supraoccipital bone property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2001950 name: inter-premaxillary joint namespace: uberon def: "Joint that articulates the left and right premaxillary bones. Inter-premaxillary joint is unpaired." [TAO:wd] xref: ZFA:0005475 is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002244 ! premaxilla relationship: connects UBERON:0002244 ! premaxilla property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2001984 name: centrum 2 namespace: uberon def: "Centrum that is part of vertebra 2." [TAO:wd] is_a: UBERON:0001075 ! bony vertebral centrum relationship: part_of UBERON:0001093 ! vertebral bone 2 property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2002260 name: premaxillary-maxillary joint namespace: uberon def: "Joint that articulates the premaxilla and maxilla. Premaxillary-maxillary joint is paired." [TAO:wd] is_a: UBERON:2001950 ! inter-premaxillary joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0002244 ! premaxilla intersection_of: connects UBERON:0002397 ! maxilla relationship: connects UBERON:0002397 ! maxilla property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2005260 name: fenestrated capillary namespace: uberon def: "Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse." [Wikipedia:Capillary#Types, Wikipedia:Fenestra_(histology)] synonym: "fenestrated blood vessel endothelium" BROAD [ZFA:0005260] synonym: "fenestrated capillary vessel" EXACT [FMA:63196] xref: FMA:63196 xref: NCIT:C32595 xref: TAO:0005260 xref: UMLS:C1179615 {source="ncithesaurus:Fenestrated_Capillary"} xref: Wikipedia:Capillary#Types xref: ZFA:0005260 is_a: UBERON:0001982 {source="FMA"} ! capillary is_a: UBERON:0004638 {source="ZFA"} ! blood vessel endothelium property_value: editor_note "the ZFA class from which this was derived is not explicitly classified as a capillary - need to verify for taxon histology differences" xsd:string property_value: UBPROP:0000001 "Blood vessel endothelium that has pores that allow passage small molecules and proteins[ZFA]." xsd:string [Term] id: UBERON:2005264 name: supraoccipital-parietal joint namespace: uberon xref: ZFA:0005609 is_a: UBERON:0000982 ! skeletal joint intersection_of: UBERON:0000982 ! skeletal joint intersection_of: connects UBERON:0004747 ! supraoccipital bone intersection_of: connects UBERON:0004865 ! actinopterygian parietal bone relationship: connects UBERON:0004747 ! supraoccipital bone relationship: connects UBERON:0004865 ! actinopterygian parietal bone property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:2007013 name: preplacodal ectoderm namespace: uberon def: "Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes." [ZFIN:curator] xref: ZFA:0007013 is_a: UBERON:0005497 ! non-neural ectoderm property_value: UBPROP:0000004 "This class was sourced from an external ontology (teleost_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/tao.owl"} [Term] id: UBERON:3000224 name: hyobranchial muscle namespace: uberon is_a: UBERON:0002376 ! cranial muscle property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000400 name: pars facialis of maxilla namespace: uberon is_a: UBERON:0000064 ! organ part is_a: UBERON:0010313 ! neural crest-derived structure relationship: part_of UBERON:0002397 ! maxilla property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000467 name: preorbital process of the pars facialis of the maxilla namespace: uberon synonym: "preorbital process" EXACT [] is_a: UBERON:0010313 ! neural crest-derived structure is_a: UBERON:4100000 ! skeletal element projection relationship: part_of UBERON:0001697 ! orbit of skull relationship: part_of UBERON:3000400 ! pars facialis of maxilla property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000774 name: ilial shaft namespace: uberon def: "Anterior rod that articulates with the sacrum." [AAO:LAP] is_a: UBERON:0000064 ! organ part is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of UBERON:0001273 ! ilium property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000784 name: ulnar condyle namespace: uberon def: "Semi-elliptical ball located at the lower end of the humerus, adjacent to the humeral ball." [AAO:LAP] synonym: "medial condyle" RELATED [UBERON:3000784] is_a: UBERON:0000064 ! organ part is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of UBERON:0000976 ! humerus property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000785 name: trochlear groove of humerus namespace: uberon def: "Furrow between the humeral head and the ulnar condyle." [AAO:LAP] synonym: "trochlear sulcus of humerus" EXACT [] is_a: UBERON:0000064 ! organ part is_a: UBERON:0004120 ! mesoderm-derived structure relationship: part_of UBERON:0000976 ! humerus property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000840 name: capitulum of radius namespace: uberon def: "Lateral portion of the proximal (upper) articular surface of the radius that consists of an eminence with a rounded apex." [AAO:LAP] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone relationship: part_of UBERON:0001423 ! radius bone property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000961 name: external integument structure namespace: uberon def: "Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument." [AAO:EJS] comment: Not clear how this differs from parent class. See https://github.com/obophenotype/uberon/issues/1305 is_a: UBERON:0003102 ! surface structure intersection_of: UBERON:0003102 ! surface structure intersection_of: part_of UBERON:0002199 ! integument relationship: part_of UBERON:0002199 ! integument property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000972 name: head external integument structure namespace: uberon def: "Dermal, epidermal, glandular and pigment structures of the external head integument." [AAO:EJS] is_a: UBERON:3000961 ! external integument structure intersection_of: UBERON:3000961 ! external integument structure intersection_of: part_of UBERON:0000033 ! head relationship: part_of UBERON:0000033 ! head property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000977 name: body external integument structure namespace: uberon def: "Dermal, epidermal, glandular and pigment structures of the body integument." [AAO:EJS] is_a: UBERON:3000961 ! external integument structure intersection_of: UBERON:3000961 ! external integument structure intersection_of: part_of UBERON:0002100 ! trunk relationship: part_of UBERON:0002100 ! trunk property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000981 name: limb external integument structure namespace: uberon def: "Dermal, epidermal, glandular and pigment structures of the limb integument." [AAO:EJS] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:3000961 ! external integument structure intersection_of: UBERON:3000961 ! external integument structure intersection_of: part_of UBERON:0002101 ! limb relationship: part_of UBERON:0002101 ! limb property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3000982 name: tail external integument structure namespace: uberon def: "Dermal, epidermal, glandular and pigment structures of the tail integument." [AAO:EJS] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:3000961 ! external integument structure intersection_of: UBERON:3000961 ! external integument structure intersection_of: part_of UBERON:0007812 ! post-anal tail relationship: part_of UBERON:0007812 ! post-anal tail property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3010200 name: vasculature of respiratory integument namespace: uberon def: "Blood vessels in respiratory skin." [AAO:EJS] is_a: UBERON:0003504 ! respiratory system blood vessel intersection_of: UBERON:0001981 ! blood vessel intersection_of: part_of UBERON:0001004 ! respiratory system intersection_of: part_of UBERON:0002199 ! integument relationship: part_of UBERON:0002199 ! integument property_value: editor_note "Modified from the original AAO source" xsd:string property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3010654 name: rectus cervicis namespace: uberon def: "Retracts the hyoid and, therefore, the tongue." [AAO:BMZ] is_a: UBERON:3000224 ! hyobranchial muscle property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:3010692 name: m. cucullaris namespace: uberon def: "Muscle which originates on the prootic and the otic ramus of the squamosal and inserts on the anterior border of the suprascapula." [AAO:MEJ] is_a: UBERON:0010891 ! pectoral complex muscle property_value: UBPROP:0000004 "This class was sourced from an external ontology (amphibian_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/aao.owl"} [Term] id: UBERON:4000013 name: mineralized skeletal tissue namespace: uberon def: "Skeletal tissue that is mineralized." [XAO:0004039, XAO:EJS] synonym: "mineralized tissue" BROAD [VSAO:0000013] xref: VSAO:0000013 xref: XAO:0004039 is_a: UBERON:0004755 ! skeletal tissue intersection_of: UBERON:0004755 ! skeletal tissue intersection_of: has_quality PATO:0002444 ! mineralized relationship: has_quality PATO:0002444 ! mineralized [Term] id: UBERON:4000020 name: mineralized extracellular matrix namespace: uberon def: "Extracellular matrix that is mineralized." [PSPUB:0000170] is_a: GO:0031012 ! extracellular matrix is_a: UBERON:0000479 ! tissue property_value: UBPROP:0000004 "This class was sourced from an external ontology (vertebrate_skeletal_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/vsao.owl"} [Term] id: UBERON:4000115 name: mineralized bone tissue namespace: uberon def: "Bone tissue mineralized with hydroxyapatite." [PSPUB:0000170] is_a: UBERON:0002481 ! bone tissue is_a: UBERON:4000013 ! mineralized skeletal tissue intersection_of: UBERON:0002481 ! bone tissue intersection_of: has_quality PATO:0002444 ! mineralized relationship: develops_from UBERON:0008883 ! osteoid relationship: has_part CHEBI:52255 ! hydroxylapatite relationship: has_part UBERON:4000020 ! mineralized extracellular matrix property_value: UBPROP:0000004 "This class was sourced from an external ontology (vertebrate_skeletal_anatomy). Its definitions, naming conventions and relationships may need to be checked for compatibility with uberon" xsd:string {source="http://purl.obolibrary.org/obo/vsao.owl"} [Term] id: UBERON:4100000 name: skeletal element projection namespace: uberon def: "Anatomical projection that is composed of bone or cartilage tissue." [PHENOSCAPE] is_a: UBERON:0004529 ! anatomical projection intersection_of: UBERON:0004529 ! anatomical projection intersection_of: part_of UBERON:0004765 ! skeletal element relationship: part_of UBERON:0004765 ! skeletal element [Term] id: UBERON:4100003 name: articular surface namespace: uberon def: "Anatomical surface that is part of a skeletal element and articulates with another skeletal element." [PHENOSCAPE:NI] comment: Not necessarily part of a joint. is_a: UBERON:0006984 ! anatomical surface relationship: dc-contributor https://orcid.org/0000-0001-5839-6798 relationship: part_of UBERON:0004765 ! skeletal element [Term] id: UBERON:4100008 name: obsolete pedal claws namespace: uberon def: "OBSOLETE Claws on the pes." [PHENOSCAPE] comment: Term is redundant with 'nail of pedal digit' (UBERON:0009567). property_value: seeAlso "https://github.com/obophenotype/uberon/issues/1699" xsd:string is_obsolete: true replaced_by: UBERON:0009567 [Term] id: UBERON:4200133 name: crest namespace: uberon def: "A ridge or similar projection rising above the surface of an anatomical structure." [PHENOSCAPE] is_a: UBERON:0004529 ! anatomical projection relationship: dc-contributor https://orcid.org/0000-0001-7972-3866 [Term] id: UBERON:4200172 name: neck of humerus namespace: uberon synonym: "anatomic neck of humerus" RELATED [FMA:23356] synonym: "collum anatomicum (Humerus)" EXACT [FMA:23356] synonym: "collum anatomicum humeri" EXACT LATIN [FMA:23356, FMA:TA] synonym: "humeral neck" EXACT [] xref: FMA:23356 xref: NCIT:C33164 is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0018664 ! neck of bone element intersection_of: UBERON:0001560 ! neck of organ intersection_of: part_of UBERON:0000976 ! humerus relationship: part_of UBERON:0004411 ! proximal epiphysis of humerus [Term] id: UBERON:4200174 name: distal condyle of humerus namespace: uberon def: "The area encompassing the radial and ulnar condyles of the humerus." [PHENOSCAPE] is_a: UBERON:0009988 ! condyle of humerus relationship: has_part UBERON:0010853 ! capitulum of humerus relationship: has_part UBERON:3000784 ! ulnar condyle [Term] id: UBERON:4200181 name: astragalus head namespace: uberon def: "The region of the astragalus/ talus that carries the articular surface for the navicular or central metatarsal." [PHENOSCAPE] synonym: "talus head" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005913 ! zone of bone organ relationship: part_of UBERON:0002395 ! talus [Term] id: UBERON:4200203 name: humeral facet on the ulna namespace: uberon def: "Facet on the ulna for articulation with the ulnar condyle of the humerus." [PHENOSCAPE] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone is_a: UBERON:4300038 ! facet relationship: part_of UBERON:0001424 ! ulna [Term] id: UBERON:4200204 name: humeral facet on radius namespace: uberon def: "Facet on the radius for articulation with the radial condyle of the humerus." [PHENOSCAPE] synonym: "proximal articular surface of radius" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone is_a: UBERON:4300038 ! facet relationship: part_of UBERON:0001423 ! radius bone [Term] id: UBERON:4200219 name: middle phalanx of manual digit 1 namespace: uberon is_a: UBERON:0003620 ! manual digit 1 phalanx is_a: UBERON:0003864 ! middle phalanx of manus [Term] id: UBERON:4200230 name: surface of bone namespace: uberon def: "An anatomical surface that is part of a bone." [PHENOSCAPE] synonym: "bone surface" EXACT [] is_a: UBERON:0006984 ! anatomical surface intersection_of: UBERON:0006984 ! anatomical surface intersection_of: part_of UBERON:0001474 ! bone element relationship: part_of UBERON:0001474 ! bone element [Term] id: UBERON:4300038 name: facet namespace: uberon def: "A small smooth area on a bone or other firm structure. A worn spot on a tooth, produced by chewing or grinding." [http://medical-dictionary.thefreedictionary.com/facet] is_a: UBERON:0006984 ! anatomical surface relationship: dc-contributor https://orcid.org/0000-0003-3162-7490 relationship: part_of UBERON:0004765 ! skeletal element [Term] id: UBERON:4300226 name: forelimb bud mesenchyme namespace: uberon def: "Mesenchyme that is part of a forelimb bud." [PHENOSCAPE] is_a: UBERON:0003413 ! pectoral appendage bud mesenchyme is_a: UBERON:0010328 ! limb bud mesenchyme intersection_of: UBERON:0010328 ! limb bud mesenchyme intersection_of: part_of UBERON:0005417 ! forelimb bud relationship: dc-contributor https://orcid.org/0000-0003-3162-7490 relationship: part_of UBERON:0005417 ! forelimb bud [Term] id: UBERON:4300227 name: hindlimb bud mesenchyme namespace: uberon def: "Mesenchyme that is part of a hindlimb bud." [PHENOSCAPE] is_a: UBERON:0003412 ! pelvic appendage bud mesenchyme is_a: UBERON:0010328 ! limb bud mesenchyme intersection_of: UBERON:0010328 ! limb bud mesenchyme intersection_of: part_of UBERON:0005418 ! hindlimb bud relationship: dc-contributor https://orcid.org/0000-0003-3162-7490 relationship: part_of UBERON:0005418 ! hindlimb bud [Term] id: UBERON:5001463 name: manual digit 1 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of manual digit 1 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 1" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 1 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 1 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 1 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit I plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002389 ! manual digit plus metapodial segment is_a: UBERON:5006048 ! digit 1 plus metapodial segment intersection_of: UBERON:5006048 ! digit 1 plus metapodial segment intersection_of: part_of UBERON:0002398 ! manus relationship: has_part UBERON:0001463 ! manual digit 1 relationship: has_skeleton UBERON:5101463 ! manual digit 1 digitopodial skeleton relationship: part_of UBERON:0002398 ! manus property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5001466 name: pedal digit plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of pedal digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit ray" EXACT [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:5002544 ! digit plus metapodial segment intersection_of: UBERON:5002544 ! digit plus metapodial segment intersection_of: part_of UBERON:0002387 ! pes relationship: has_part UBERON:0001466 ! pedal digit relationship: has_skeleton UBERON:5101466 ! pedal digit digitopodial skeleton relationship: part_of UBERON:0002387 ! pes property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5002389 name: manual digit plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of manual digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit ray" EXACT [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:5002544 ! digit plus metapodial segment intersection_of: UBERON:5002544 ! digit plus metapodial segment intersection_of: part_of UBERON:0002102 ! forelimb relationship: has_part UBERON:0002389 ! manual digit relationship: has_skeleton UBERON:5102389 ! manual digit digitopodial skeleton relationship: part_of UBERON:0002102 ! forelimb property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5002544 name: digit plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "digit" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "digit ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit ray" EXACT [http://orcid.org/0000-0002-6601-2165] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0000475 ! organism subdivision intersection_of: UBERON:0000475 ! organism subdivision intersection_of: has_skeleton UBERON:5102544 ! individual digit of digitopodial skeleton relationship: has_part UBERON:0002544 ! digit relationship: has_skeleton UBERON:5102544 ! individual digit of digitopodial skeleton relationship: part_of UBERON:0012140 ! digitopodium region property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003622 name: manual digit 2 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of manual digit 2 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 2" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 2 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 2 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 2 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit II plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002389 ! manual digit plus metapodial segment is_a: UBERON:5006049 ! digit 2 plus metapodial segment intersection_of: UBERON:5006049 ! digit 2 plus metapodial segment intersection_of: part_of UBERON:0002398 ! manus relationship: has_part UBERON:0003622 ! manual digit 2 relationship: has_skeleton UBERON:5103622 ! manual digit 2 digitopodial skeleton relationship: part_of UBERON:0002398 ! manus property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003623 name: manual digit 3 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of manual digit 3 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 3" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 3 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 3 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 3 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit III plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002389 ! manual digit plus metapodial segment is_a: UBERON:5006050 ! digit 3 plus metapodial segment intersection_of: UBERON:5006050 ! digit 3 plus metapodial segment intersection_of: part_of UBERON:0002398 ! manus relationship: has_part UBERON:0003623 ! manual digit 3 relationship: has_skeleton UBERON:5103623 ! manual digit 3 digitopodial skeleton relationship: part_of UBERON:0002398 ! manus property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003624 name: manual digit 4 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of manual digit 4 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 4" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 4 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 4 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 4 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit IV plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002389 ! manual digit plus metapodial segment is_a: UBERON:5006051 ! digit 4 plus metapodial segment intersection_of: UBERON:5006051 ! digit 4 plus metapodial segment intersection_of: part_of UBERON:0002398 ! manus relationship: has_part UBERON:0003624 ! manual digit 4 relationship: has_skeleton UBERON:5103624 ! manual digit 4 digitopodial skeleton relationship: part_of UBERON:0002398 ! manus property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003625 name: manual digit 5 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of manual digit 5 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 5" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 5 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 5 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 5 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit V plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002389 ! manual digit plus metapodial segment is_a: UBERON:5006052 ! digit 5 plus metapodial segment intersection_of: UBERON:5006052 ! digit 5 plus metapodial segment intersection_of: part_of UBERON:0002398 ! manus relationship: has_part UBERON:0003625 ! manual digit 5 relationship: has_skeleton UBERON:5103625 ! manual digit 5 digitopodial skeleton relationship: part_of UBERON:0002398 ! manus property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003631 name: pedal digit 1 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of pedal digit 1 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 1" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 1 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 1 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 1 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit I plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5001466 ! pedal digit plus metapodial segment is_a: UBERON:5006048 ! digit 1 plus metapodial segment intersection_of: UBERON:5006048 ! digit 1 plus metapodial segment intersection_of: part_of UBERON:0002387 ! pes relationship: has_part UBERON:0003631 ! pedal digit 1 relationship: has_skeleton UBERON:5103631 ! pedal digit 1 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003632 name: pedal digit 2 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of pedal digit 2 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 2" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 2 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 2 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 2 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit II plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5001466 ! pedal digit plus metapodial segment is_a: UBERON:5006049 ! digit 2 plus metapodial segment intersection_of: UBERON:5006049 ! digit 2 plus metapodial segment intersection_of: part_of UBERON:0002387 ! pes relationship: has_part UBERON:0003632 ! pedal digit 2 relationship: has_skeleton UBERON:5103632 ! pedal digit 2 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003633 name: pedal digit 3 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of pedal digit 3 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 3" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 3 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 3 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 3 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit III plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5001466 ! pedal digit plus metapodial segment is_a: UBERON:5006050 ! digit 3 plus metapodial segment intersection_of: UBERON:5006050 ! digit 3 plus metapodial segment intersection_of: part_of UBERON:0002387 ! pes relationship: has_part UBERON:0003633 ! pedal digit 3 relationship: has_skeleton UBERON:5103633 ! pedal digit 3 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003634 name: pedal digit 4 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of pedal digit 4 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 4" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 4 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 4 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 4 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit IV plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5001466 ! pedal digit plus metapodial segment is_a: UBERON:5006051 ! digit 4 plus metapodial segment intersection_of: UBERON:5006051 ! digit 4 plus metapodial segment intersection_of: part_of UBERON:0002387 ! pes relationship: has_part UBERON:0003634 ! pedal digit 4 relationship: has_skeleton UBERON:5103634 ! pedal digit 4 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5003635 name: pedal digit 5 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of pedal digit 5 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 5" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 5 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 5 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 5 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit V plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5001466 ! pedal digit plus metapodial segment is_a: UBERON:5006052 ! digit 5 plus metapodial segment intersection_of: UBERON:5006052 ! digit 5 plus metapodial segment intersection_of: part_of UBERON:0002387 ! pes relationship: has_part UBERON:0003635 ! pedal digit 5 relationship: has_skeleton UBERON:5103635 ! pedal digit 5 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5006048 name: digit 1 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of digit 1 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 1" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "digit 1 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 1 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit 1 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit I plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002544 ! digit plus metapodial segment intersection_of: UBERON:5002544 ! digit plus metapodial segment intersection_of: has_skeleton UBERON:5106048 ! digit 1 digitopodial skeleton relationship: has_part UBERON:0006048 ! digit 1 relationship: has_skeleton UBERON:5106048 ! digit 1 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5006049 name: digit 2 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of digit 2 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 2" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "digit 2 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 2 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit 2 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit II plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002544 ! digit plus metapodial segment intersection_of: UBERON:5002544 ! digit plus metapodial segment intersection_of: has_skeleton UBERON:5106049 ! digit 2 digitopodial skeleton relationship: has_part UBERON:0006049 ! digit 2 relationship: has_skeleton UBERON:5106049 ! digit 2 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5006050 name: digit 3 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of digit 3 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 3" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "digit 3 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 3 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit 3 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit III plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002544 ! digit plus metapodial segment intersection_of: UBERON:5002544 ! digit plus metapodial segment intersection_of: has_skeleton UBERON:5106050 ! digit 3 digitopodial skeleton relationship: has_part UBERON:0006050 ! digit 3 relationship: has_skeleton UBERON:5106050 ! digit 3 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5006051 name: digit 4 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of digit 4 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 4" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "digit 4 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 4 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit 4 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit IV plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002544 ! digit plus metapodial segment intersection_of: UBERON:5002544 ! digit plus metapodial segment intersection_of: has_skeleton UBERON:5106051 ! digit 4 digitopodial skeleton relationship: has_part UBERON:0006051 ! digit 4 relationship: has_skeleton UBERON:5106051 ! digit 4 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5006052 name: digit 5 plus metapodial segment namespace: uberon def: "A subdivision of the autopod consisting of digit 5 plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 5" BROAD [http://orcid.org/0000-0002-6601-2165] synonym: "digit 5 ( phalanges plus metapodial) plus soft tissue" BROAD COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 5 digitopodial subdivision" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit 5 ray" EXACT [http://orcid.org/0000-0002-6601-2165] synonym: "digit V plus metapodial segment" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5002544 ! digit plus metapodial segment intersection_of: UBERON:5002544 ! digit plus metapodial segment intersection_of: has_skeleton UBERON:5106052 ! digit 5 digitopodial skeleton relationship: has_part UBERON:0006052 ! digit 5 relationship: has_skeleton UBERON:5106052 ! digit 5 digitopodial skeleton property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element plus associated soft tissues. Instances of this class typically do not form a distinct unit." xsd:string {source="https://github.com/obophenotype/uberon/issues/458"} [Term] id: UBERON:5101463 name: manual digit 1 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit 1 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 1" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 1 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit I digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102389 ! manual digit digitopodial skeleton is_a: UBERON:5106048 ! digit 1 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5001463 ! manual digit 1 plus metapodial segment relationship: part_of UBERON:5001463 ! manual digit 1 plus metapodial segment relationship: skeleton_of UBERON:5001463 ! manual digit 1 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5101466 name: pedal digit digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:5102544 ! individual digit of digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5001466 ! pedal digit plus metapodial segment relationship: part_of UBERON:5001466 ! pedal digit plus metapodial segment relationship: skeleton_of UBERON:5001466 ! pedal digit plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5102389 name: manual digit digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] is_a: UBERON:5102544 ! individual digit of digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5002389 ! manual digit plus metapodial segment relationship: part_of UBERON:5002389 ! manual digit plus metapodial segment relationship: skeleton_of UBERON:5002389 ! manual digit plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5102544 name: individual digit of digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of a single digit plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "digit" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] is_a: CARO:0000003 ! connected anatomical structure is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0010712 ! limb skeleton subdivision intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5002544 ! digit plus metapodial segment relationship: part_of UBERON:0012150 ! skeleton of digitopodium relationship: part_of UBERON:5002544 ! digit plus metapodial segment relationship: skeleton_of UBERON:5002544 ! digit plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103622 name: manual digit 2 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit 2 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 2" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 2 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit II digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102389 ! manual digit digitopodial skeleton is_a: UBERON:5106049 ! digit 2 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003622 ! manual digit 2 plus metapodial segment relationship: part_of UBERON:5003622 ! manual digit 2 plus metapodial segment relationship: skeleton_of UBERON:5003622 ! manual digit 2 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103623 name: manual digit 3 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit 3 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 3" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 3 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit III digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102389 ! manual digit digitopodial skeleton is_a: UBERON:5106050 ! digit 3 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003623 ! manual digit 3 plus metapodial segment relationship: part_of UBERON:5003623 ! manual digit 3 plus metapodial segment relationship: skeleton_of UBERON:5003623 ! manual digit 3 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103624 name: manual digit 4 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit 4 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 4" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 4 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit IV digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102389 ! manual digit digitopodial skeleton is_a: UBERON:5106051 ! digit 4 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003624 ! manual digit 4 plus metapodial segment relationship: part_of UBERON:5003624 ! manual digit 4 plus metapodial segment relationship: skeleton_of UBERON:5003624 ! manual digit 4 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103625 name: manual digit 5 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of manual digit 5 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 5" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit 5 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "manual digit V digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102389 ! manual digit digitopodial skeleton is_a: UBERON:5106052 ! digit 5 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003625 ! manual digit 5 plus metapodial segment relationship: part_of UBERON:5003625 ! manual digit 5 plus metapodial segment relationship: skeleton_of UBERON:5003625 ! manual digit 5 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103631 name: pedal digit 1 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit 1 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 1" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 1 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit I digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5101466 ! pedal digit digitopodial skeleton is_a: UBERON:5106048 ! digit 1 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003631 ! pedal digit 1 plus metapodial segment relationship: part_of UBERON:5003631 ! pedal digit 1 plus metapodial segment relationship: skeleton_of UBERON:5003631 ! pedal digit 1 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103632 name: pedal digit 2 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit 2 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 2" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 2 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit II digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5101466 ! pedal digit digitopodial skeleton is_a: UBERON:5106049 ! digit 2 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003632 ! pedal digit 2 plus metapodial segment relationship: part_of UBERON:5003632 ! pedal digit 2 plus metapodial segment relationship: skeleton_of UBERON:5003632 ! pedal digit 2 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103633 name: pedal digit 3 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit 3 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 3" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 3 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit III digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5101466 ! pedal digit digitopodial skeleton is_a: UBERON:5106050 ! digit 3 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003633 ! pedal digit 3 plus metapodial segment relationship: part_of UBERON:5003633 ! pedal digit 3 plus metapodial segment relationship: skeleton_of UBERON:5003633 ! pedal digit 3 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103634 name: pedal digit 4 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit 4 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 4" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 4 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit IV digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5101466 ! pedal digit digitopodial skeleton is_a: UBERON:5106051 ! digit 4 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003634 ! pedal digit 4 plus metapodial segment relationship: part_of UBERON:5003634 ! pedal digit 4 plus metapodial segment relationship: skeleton_of UBERON:5003634 ! pedal digit 4 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5103635 name: pedal digit 5 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of pedal digit 5 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 5" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit 5 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "pedal digit V digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5101466 ! pedal digit digitopodial skeleton is_a: UBERON:5106052 ! digit 5 digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5003635 ! pedal digit 5 plus metapodial segment relationship: part_of UBERON:5003635 ! pedal digit 5 plus metapodial segment relationship: skeleton_of UBERON:5003635 ! pedal digit 5 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5106048 name: digit 1 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of digit 1 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 1" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 1 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "digit I digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102544 ! individual digit of digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5006048 ! digit 1 plus metapodial segment relationship: part_of UBERON:5006048 ! digit 1 plus metapodial segment relationship: skeleton_of UBERON:5006048 ! digit 1 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5106049 name: digit 2 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of digit 2 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 2" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 2 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "digit II digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102544 ! individual digit of digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5006049 ! digit 2 plus metapodial segment relationship: part_of UBERON:5006049 ! digit 2 plus metapodial segment relationship: skeleton_of UBERON:5006049 ! digit 2 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5106050 name: digit 3 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of digit 3 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 3" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 3 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "digit III digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102544 ! individual digit of digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5006050 ! digit 3 plus metapodial segment relationship: part_of UBERON:5006050 ! digit 3 plus metapodial segment relationship: skeleton_of UBERON:5006050 ! digit 3 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5106051 name: digit 4 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of digit 4 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 4" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 4 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "digit IV digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102544 ! individual digit of digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5006051 ! digit 4 plus metapodial segment relationship: part_of UBERON:5006051 ! digit 4 plus metapodial segment relationship: skeleton_of UBERON:5006051 ! digit 4 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:5106052 name: digit 5 digitopodial skeleton namespace: uberon def: "A subdivision of the skeleton of the autopod consisting of the phalanges of digit 5 plus the associated metapodial element." [http://orcid.org/0000-0002-6601-2165] synonym: "digit 5" RELATED COMPARATIVE_PREFERRED [http://orcid.org/0000-0002-6601-2165] synonym: "digit 5 skeleton" RELATED [http://orcid.org/0000-0002-6601-2165] synonym: "digit V digitopodial skeleton" EXACT COMPARATIVE_PREFERRED [https://github.com/obophenotype/uberon/issues/458] is_a: UBERON:5102544 ! individual digit of digitopodial skeleton intersection_of: UBERON:0010912 ! subdivision of skeleton intersection_of: skeleton_of UBERON:5006052 ! digit 5 plus metapodial segment relationship: part_of UBERON:5006052 ! digit 5 plus metapodial segment relationship: skeleton_of UBERON:5006052 ! digit 5 plus metapodial segment property_value: IAO:0000232 "this class represents a series of phalanges plus a metapodial element. In comparative anatomy terminology we would call this a 'digit', but the label 'digit' is sometimes used to exclude metapodials and to include soft tissue. This series of elements is hypothesized to be homologous to radials." xsd:string [Term] id: UBERON:6000002 name: arthropod tagma namespace: uberon def: "One of the main divisions of the whole organism of arthropods formed from groups of segments." [doi:10.1016/B978-0-12-385026-3.00024-3] comment: Strictly speaking the term "tagma" cam be used for any metameric organism, however we follow the common usage which is to restrict the term to arthropods. xref: FBbt:00000002 is_a: UBERON:0011676 ! subdivision of organism along main body axis relationship: only_in_taxon NCBITaxon:6656 ! Arthropoda property_value: RO:0002161 NCBITaxon:7742 [Term] id: UBERON:6000004 name: panarthropod head namespace: uberon xref: FBbt:00000004 is_a: UBERON:0000033 ! head intersection_of: UBERON:0000033 ! head intersection_of: part_of NCBITaxon:88770 ! Panarthropoda relationship: part_of NCBITaxon:88770 ! Panarthropoda [Term] id: UBERON:6000137 name: embryonic tagma namespace: uberon def: "Any tagma (UBERON:6000002) that is part of some embryo (UBERON:6000052)." [FBC:auto_generated_definition] xref: FBbt:00000137 is_a: UBERON:6000002 ! arthropod tagma intersection_of: UBERON:6000002 ! arthropod tagma intersection_of: part_of UBERON:0000922 ! embryo relationship: part_of UBERON:0000922 ! embryo [Term] id: UBERON:6001728 name: insect larval tagma namespace: uberon def: "Any tagma (UBERON:6000002) that is part of some larva (UBERON:6001727)." [FBC:auto_generated_definition] xref: FBbt:00001728 is_a: UBERON:6000002 ! arthropod tagma intersection_of: UBERON:6000002 ! arthropod tagma intersection_of: part_of UBERON:0002548 ! larva relationship: part_of UBERON:0002548 ! larva [Term] id: UBERON:6001730 name: insect larval head namespace: uberon def: "Any head that is part of some larva." [FBC:auto_generated_definition] xref: FBbt:00001730 is_a: UBERON:0000033 ! head intersection_of: UBERON:0000033 ! head intersection_of: only_in_taxon NCBITaxon:50557 ! Insecta intersection_of: part_of UBERON:0002548 ! larva relationship: only_in_taxon NCBITaxon:50557 ! Insecta relationship: part_of UBERON:0002548 ! larva [Term] id: UBERON:6002639 name: insect larval sense organ namespace: uberon def: "Any sense organ that is part of some larva." [FBC:auto_generated_definition] synonym: "larval sense organ" EXACT [] xref: FBbt:00002639 is_a: UBERON:0000020 ! sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: only_in_taxon NCBITaxon:50557 ! Insecta intersection_of: part_of UBERON:0002548 ! larva relationship: only_in_taxon NCBITaxon:50557 ! Insecta relationship: part_of UBERON:0002548 ! larva [Term] id: UBERON:6003005 name: insect adult tagma namespace: uberon def: "Any tagma (UBERON:6000002) that is part of some adult (UBERON:6003004)." [FBC:auto_generated_definition] xref: FBbt:00003005 is_a: UBERON:6000002 ! arthropod tagma intersection_of: UBERON:6000002 ! arthropod tagma intersection_of: part_of UBERON:0007023 ! adult organism relationship: part_of UBERON:0007023 ! adult organism [Term] id: UBERON:6003007 name: insect adult head namespace: uberon def: "Head of the adult organism." [FBC:SPR] xref: FBbt:00003007 is_a: UBERON:6000004 ! panarthropod head is_a: UBERON:6003005 ! insect adult tagma intersection_of: UBERON:0000033 ! head intersection_of: part_of NCBITaxon:50557 ! Insecta intersection_of: part_of UBERON:0007023 ! adult organism relationship: part_of NCBITaxon:50557 ! Insecta [Term] id: UBERON:6007240 name: insect embryonic/larval sensillum namespace: uberon def: "Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727)." [FBC:auto_generated_definition] synonym: "larval sensillum" EXACT [] xref: FBbt:00007240 is_a: UBERON:0002536 ! arthropod sensillum is_a: UBERON:6002639 ! insect larval sense organ intersection_of: UBERON:0002536 ! arthropod sensillum intersection_of: part_of UBERON:0002548 ! larva [Term] id: UBERON:6007242 name: insect embryonic/larval head sensillum namespace: uberon def: "Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730)." [FBC:auto_generated_definition] synonym: "larval head sensillum" NARROW [] xref: FBbt:00007242 is_a: UBERON:0000963 ! head sensillum is_a: UBERON:6007240 ! insect embryonic/larval sensillum is_a: UBERON:6007280 ! insect embryonic/larval head sense organ intersection_of: UBERON:0002536 ! arthropod sensillum intersection_of: part_of UBERON:6001730 ! insect larval head [Term] id: UBERON:6007280 name: insect embryonic/larval head sense organ namespace: uberon def: "Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730)." [FBC:auto_generated_definition] synonym: "larval head sense organ" EXACT [] xref: FBbt:00007280 is_a: UBERON:6002639 ! insect larval sense organ intersection_of: UBERON:0000020 ! sense organ intersection_of: part_of UBERON:6001730 ! insect larval head relationship: part_of UBERON:6001730 ! insect larval head [Term] id: UBERON:7500046 name: proximal-most point of head of femur namespace: uberon def: "The proximal-most point of the head of a femur." [https://orcid.org/0000-0003-2699-3066] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point intersection_of: UBERON:0006983 ! anatomical point intersection_of: proximalmost_part_of UBERON:0006767 ! head of femur relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0006767 ! head of femur relationship: proximalmost_part_of UBERON:0006767 ! head of femur [Term] id: UBERON:7500047 name: proximal-most point of head of humerus namespace: uberon def: "The proximal-most point of the head of a humerus." [https://orcid.org/0000-0003-2699-3066] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point intersection_of: UBERON:0006983 ! anatomical point intersection_of: proximalmost_part_of UBERON:0006801 ! proximal head of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0006801 ! proximal head of humerus relationship: proximalmost_part_of UBERON:0006801 ! proximal head of humerus [Term] id: UBERON:7500048 name: proximal-most point of ventral tubercle of humerus namespace: uberon def: "The proximal-most point of the ventral tubercle of a humerus." [https://orcid.org/0000-0003-2699-3066] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point intersection_of: UBERON:0006983 ! anatomical point intersection_of: proximalmost_part_of UBERON:0011187 ! ventral tubercle of humerus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0011187 ! ventral tubercle of humerus relationship: proximalmost_part_of UBERON:0011187 ! ventral tubercle of humerus [Term] id: UBERON:7500049 name: proximal-most point of greater trochanter of femur namespace: uberon def: "The proximal-most point of the greater trochanter of a femur." [https://orcid.org/0000-0003-2699-3066] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point intersection_of: UBERON:0006983 ! anatomical point intersection_of: proximalmost_part_of UBERON:0002503 ! greater trochanter relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0002503 ! greater trochanter relationship: proximalmost_part_of UBERON:0002503 ! greater trochanter [Term] id: UBERON:7500053 name: lower fourth secondary premolar tooth namespace: uberon def: "The premolar tooth of the lower jaw that is phylogenetically number 4." [https://orcid.org/0000-0003-2699-3066] synonym: "lower fourth permanent premolar tooth" EXACT [] synonym: "p4" RELATED ABBREVIATION [] is_a: UBERON:0016453 ! lower secondary premolar tooth is_a: UBERON:0018647 ! premolar tooth 4 intersection_of: UBERON:0018647 ! premolar tooth 4 intersection_of: part_of UBERON:0001710 ! lower jaw region intersection_of: part_of UBERON:0007774 ! secondary dentition relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500055 name: molar tooth 4 namespace: uberon def: "The molar tooth of the upper or lower jaw that is phylogenetically number 4." [https://orcid.org/0000-0003-2699-3066] synonym: "fourth molar tooth" EXACT [] synonym: "molar 4" EXACT [] synonym: "molar 4 tooth" EXACT [] is_a: UBERON:0003655 ! molar tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500056 name: premolar 3 namespace: uberon def: "The premolar tooth of the upper or lower jaw that is phylogenetically number 3." [https://orcid.org/0000-0003-2699-3066] synonym: "premolar tooth 3" EXACT [] synonym: "third premolar tooth" EXACT [] is_a: UBERON:0007120 ! premolar tooth relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500061 name: trochlear ridge of humerus namespace: uberon def: "The ridge of the trochlea on a humerus lies in the middle of the distal end of a humerus on the lateral side of the trochlea and the medial side of the capitulum (capitellum)." [https://orcid.org/0000-0003-2699-3066] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0000144 ! trochlea of humerus [Term] id: UBERON:7500062 name: tibial tuberosity namespace: uberon def: "The tibial tuberosity is on the anterior side of a tibia and is where a patella ligament attaches." [https://en.wikipedia.org/wiki/Tuberosity_of_the_tibia] synonym: "fossa digitalis" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005813 ! tubercle is_a: UBERON:4100000 ! skeletal element projection intersection_of: UBERON:0005813 ! tubercle intersection_of: part_of UBERON:0008772 ! proximal epiphysis of tibia relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0008772 ! proximal epiphysis of tibia [Term] id: UBERON:7500063 name: trochlea of talus namespace: uberon def: "The articular surface of a talus that interacts with a tibia. It has a deep depression that forms the trochlear groove and is bounded by the medial and lateral condyles." [https://en.wikipedia.org/wiki/Talus_bone] synonym: "trochlea for tibia" EXACT [] synonym: "trochlea of astragalus" EXACT [] synonym: "trochlea tali" EXACT [] is_a: UBERON:7500081 ! articular surface for the tibia on the talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500064 name: trochlear groove of talus namespace: uberon def: "The furrow between the lateral and medial condyles of the trochlea of talus." [https://en.wikipedia.org/wiki/Talus_bone] synonym: "trochlear groove of astragalus" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0002395 ! talus [Term] id: UBERON:7500065 name: condyle of talus namespace: uberon def: "An articular prominence of a talus that engages with the tibia." [http://orcid.org/0000-0003-2699-3066] synonym: "condyle of astragalus" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0009979 ! condyle intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0002395 ! talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0002395 ! talus [Term] id: UBERON:7500066 name: medial condyle of talus namespace: uberon def: "The medial condyle of talus is an articular prominence of bone on medial side of the trochlea of a talus, which engages with the tibia." [https://orcid.org/0000-0003-2699-3066] synonym: "medial condyle of astragalus" EXACT [] is_a: UBERON:7500065 ! condyle of talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500067 name: lateral condyle of talus namespace: uberon def: "The lateral condyle of talus is an articular prominence of bone on the lateral side of the trochlea of a talus, which engages with the tibia." [https://orcid.org/0000-0003-2699-3066] synonym: "lateral condyle of astragalus" EXACT [] is_a: UBERON:7500065 ! condyle of talus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500068 name: ridge of medial condyle of talus namespace: uberon def: "The crest of the medial condyle of a talus." [https://orcid.org/0000-0003-2699-3066] synonym: "ridge of medial condyle of astragalus" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:7500066 ! medial condyle of talus [Term] id: UBERON:7500069 name: ridge of lateral condyle of talus namespace: uberon def: "The crest of the lateral condyle of a talus." [https://orcid.org/0000-0003-2699-3066] synonym: "ridge of lateral condyle of astragalus" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:7500067 ! lateral condyle of talus [Term] id: UBERON:7500070 name: sulcus tali namespace: uberon def: "A depression that runs between the two facets of a talus that interact with a calcaneum." [https://en.wikipedia.org/wiki/Talus_bone] synonym: "sulcus for flexor hallucis longus tendon" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0000093 ! sulcus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0002395 ! talus [Term] id: UBERON:7500071 name: rostrum namespace: uberon def: "An anatomical structure that protrudes from the head region. In vertebrates, this includes the part of the cranium (skull) in front of the zygomatic arches that also holds the teeth, palat, and nasal cavity. In invertebrates it is the forward extension of the carapace and/or the piercing mouthparts." [http://orcid.org/0000-0003-2699-3066] synonym: "beak" RELATED [] synonym: "muzzle" RELATED [] synonym: "snout" RELATED [] is_a: UBERON:0000475 ! organism subdivision relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0003128 ! cranium relationship: part_of UBERON:0004089 ! midface property_value: RO:0002161 NCBITaxon:9606 [Term] id: UBERON:7500073 name: left nasal bone namespace: uberon def: "Nasal bone on the left side of an organism when in anatomical position." [http://orcid.org/0000-0003-2699-3066] is_a: UBERON:0001681 ! nasal bone intersection_of: UBERON:0001681 ! nasal bone intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: in_left_side_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:7500074 name: right nasal bone namespace: uberon def: "Nasal bone on the right side of an organism when in anatomical position." [http://orcid.org/0000-0003-2699-3066] is_a: UBERON:0001681 ! nasal bone intersection_of: UBERON:0001681 ! nasal bone intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: in_right_side_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:7500075 name: left zygomatic arch namespace: uberon def: "Zygomatic arch on the left side of an organism when in anatomical position." [http://orcid.org/0000-0003-2699-3066] is_a: UBERON:0002500 ! zygomatic arch intersection_of: UBERON:0002500 ! zygomatic arch intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: in_left_side_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:7500076 name: right zygomatic arch namespace: uberon def: "Zygomatic arch on the right side of an organism when in anatomical position." [http://orcid.org/0000-0003-2699-3066] is_a: UBERON:0002500 ! zygomatic arch intersection_of: UBERON:0002500 ! zygomatic arch intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: in_right_side_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:7500077 name: obsolete trochlea of femur namespace: uberon def: "A trochlea on the distal end of a femur that interacts with the patella." [https://www.imaios.com/en/e-Anatomy/Anatomical-Parts/patellar-surface] property_value: http://purl.org/dc/terms/date "2021-06-02T00:19:07Z" xsd:dateTime is_obsolete: true replaced_by: UBERON:4200096 [Term] id: UBERON:7500078 name: styloid process of radius namespace: uberon def: "A condyle on the distal end and lateral side of a radius." [https://en.wikipedia.org/wiki/Radial_styloid_process] synonym: "radial condyle" EXACT [] synonym: "radial styloid process" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005055 ! zone of long bone is_a: UBERON:0009979 ! condyle intersection_of: UBERON:0009979 ! condyle intersection_of: part_of UBERON:0004407 ! distal epiphysis of radius relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0004407 ! distal epiphysis of radius [Term] id: UBERON:7500079 name: ulnar notch of radius namespace: uberon def: "A condyle on the distal end and medial side of a radius that interacts with the ulna." [https://en.wikipedia.org/wiki/Ulnar_notch_of_the_radius] synonym: "sigmoid cavity" EXACT [] synonym: "ulnar condyle of radius" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: in_taxon NCBITaxon:9788 ! Equidae relationship: part_of UBERON:0004407 ! distal epiphysis of radius [Term] id: UBERON:7500080 name: articular surface for carpals namespace: uberon def: "The articular surface on the distal end of a radius that interacts with carpals." [https://orcid.org/0000-0003-2699-3066] synonym: "distal articular surface of radius" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4100003 ! articular surface is_a: UBERON:4200230 ! surface of bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0004407 ! distal epiphysis of radius [Term] id: UBERON:7500081 name: articular surface for the tibia on the talus namespace: uberon def: "Contact surface between the tibia and the talus located on the talus." [https://en.wikipedia.org/wiki/Talus_bone] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4100003 ! articular surface is_a: UBERON:4200230 ! surface of bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0002395 ! talus [Term] id: UBERON:7500089 name: posterior articular facet for talus of calcaneus namespace: uberon def: "Posterior-most facet on the proximal surface of the calcaneus for the articulation of the talus bone." [https://orcid.org/0000-0003-2699-3066] synonym: "proximal facet of calcaneum" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone is_a: UBERON:4300038 ! facet relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0001450 ! calcaneus [Term] id: UBERON:7500091 name: middle articular facet for talus of calcaneus namespace: uberon def: "Middle facet on the proximal surface of the calcaneus for the articulation of the talus bone." [https://orcid.org/0000-0003-2699-3066] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone is_a: UBERON:4300038 ! facet relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0001450 ! calcaneus [Term] id: UBERON:7500092 name: anterior articular facet for talus of calcaneus namespace: uberon def: "Anterior-most facet on the proximal surface of the calcaneus for the articulation of the talus bone." [https://orcid.org/0000-0003-2699-3066] synonym: "distal facet of calcaneum" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4200230 ! surface of bone is_a: UBERON:4300038 ! facet relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0001450 ! calcaneus [Term] id: UBERON:7500093 name: calcaneal body namespace: uberon def: "The calcaneus body is the part of the bone not used for articulation with other bones." [https://orcid.org/0000-0003-2699-3066] synonym: "corpus calcanei" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005913 ! zone of bone organ relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0001450 ! calcaneus [Term] id: UBERON:7500094 name: tubercle of calcaneus namespace: uberon def: "A raised projection on the calcaneus." [https://orcid.org/0000-0003-2699-3066] synonym: "calcaneal tubercle" EXACT [] synonym: "calcaneal tuberosity" EXACT [] synonym: "tuberosity of calcaneus" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005813 ! tubercle is_a: UBERON:4100000 ! skeletal element projection intersection_of: UBERON:0005813 ! tubercle intersection_of: part_of UBERON:0001450 ! calcaneus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0001450 ! calcaneus [Term] id: UBERON:7500095 name: lateral tubercle of calcaneus namespace: uberon def: "A raised projection on the lateral side of a calcaneus." [https://orcid.org/0000-0003-2699-3066] synonym: "lateral tuberosity of calcaneus" EXACT [] is_a: UBERON:7500094 ! tubercle of calcaneus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500096 name: medial tubercle of calcaneus namespace: uberon def: "A raised projection on the medial side of a calcaneus." [https://orcid.org/0000-0003-2699-3066] synonym: "medial tuberosity of calcaneus" EXACT [] is_a: UBERON:7500094 ! tubercle of calcaneus relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500101 name: antorbital notch namespace: uberon def: "The antorbital notch is a prominence of bone located anterolaterally of the antorbital fenestra." [doi:10.5479/si.00810282.627] is_a: UBERON:4200230 ! surface of bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0003129 ! skull property_value: RO:0002175 NCBITaxon:9721 property_value: RO:0002175 NCBITaxon:9788 [Term] id: UBERON:7500105 name: coracoid process of calcaneus namespace: uberon def: "At the dorsal part of the base of the calcaneal tuberoisty is a pointed process called the coracoid process." [https://link.springer.com/article/10.1007/s00276-003-0220-0, https://www.imaios.com/en/vet-Anatomy/Vet-Anatomical-Part/Coracoid-process2] synonym: "processus coracoideus of calcaneus" EXACT [] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005913 ! zone of bone organ relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:7500094 ! tubercle of calcaneus [Term] id: UBERON:7500106 name: hormion namespace: uberon def: "A craniometric point at the junction of the posterior midline border of the vomer with the sphenoid bone on the sphenovomerine suture." [https://locatelambda.org/manual, https://medical-dictionary.thefreedictionary.com/hormion, ISBN:9780873659505] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:7500107 ! sphenovomerine suture property_value: depicted_by "http://locatelambda.org/wp-content/uploads/2018/02/hormion.jpg" xsd:string [Term] id: UBERON:7500107 name: sphenovomerine suture namespace: uberon def: "A suture joining a sphenoid bone with the alae of a vomer to form a schindylesis type of joint." [DOI:10.1097/SCS.0000000000002945, PMID:27483100] is_a: UBERON:0009199 ! facial suture intersection_of: UBERON:0009199 ! facial suture intersection_of: connects UBERON:0001677 ! sphenoid bone intersection_of: connects UBERON:0002396 ! vomer relationship: connects UBERON:0001677 ! sphenoid bone relationship: connects UBERON:0002396 ! vomer relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500108 name: cheek tooth namespace: uberon def: "Any of the post-canine teeth, which are the multicuspidate molars or premolars used for shearing and grinding food in mammals." [Wikipedia:Cheek_teeth] synonym: "cheek teeth" RELATED PLURAL [] synonym: "cheekteeth" RELATED PLURAL [] synonym: "cheektooth" EXACT [] is_a: UBERON:0013164 ! molariform tooth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500109 name: basion namespace: uberon def: "An anatomical point on the antero-ventral margin of foramen magnum in the median plane." [ISBN:9780873659505] is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0003687 ! foramen magnum [Term] id: UBERON:7500110 name: synsphenion namespace: uberon def: "A craniometric point on the ventral surface of the intersphenoid suture, along the midline of the skull." [ISBN:9780873659505] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:7500111 ! intersphenoid suture [Term] id: UBERON:7500111 name: intersphenoid suture namespace: uberon def: "A suture joining the basisphenoid bone and the presphenoid bone of a sphenoid bone." [ISBN:9780873659505] synonym: "intersphenoidal synchondrosis" EXACT [DOI:10.1038/s41598-022-04783-1] is_a: UBERON:0009199 ! facial suture intersection_of: UBERON:0009199 ! facial suture intersection_of: connects UBERON:0006428 ! basisphenoid bone intersection_of: connects UBERON:0008828 ! presphenoid bone relationship: connects UBERON:0006428 ! basisphenoid bone relationship: connects UBERON:0008828 ! presphenoid bone relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 property_value: UBPROP:0000011 "This fuses in childhood in humans." xsd:string {xref="DOI:10.2214/ajr.104.1.184"} [Term] id: UBERON:7500112 name: prosthion namespace: uberon def: "A craniometric point that is the most anterior point in the midline on the alveolar process of the maxilla between the incisors (premaxilla bone)." [DOI:10.1002/ar.a.10052, ISBN:97808736590505] comment: Often this point is midway between the median upper incisor teeth. In ruminants and pigs this point is projected into space. synonym: "alveolar point" EXACT [https://www.vocabulary.com/dictionary/alveolar%20point] synonym: "prostheon" EXACT [https://medical-dictionary.thefreedictionary.com/prostheon] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0002244 ! premaxilla [Term] id: UBERON:7500113 name: akrokranion namespace: uberon def: "The most dorsoanterior point on the supraoccipital crest in the medial plane." [ISBN:9780873659505] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:2001783 ! supraoccipital crest [Term] id: UBERON:7500114 name: cheek tooth row namespace: uberon def: "An anatomical row consisting of adjacent cheek teeth." [https://orcid.org/0000-0003-2699-3066] synonym: "cheektooth row" EXACT [https://orcid.org/0000-0003-2699-3066] is_a: UBERON:0009678 ! tooth row intersection_of: UBERON:0034926 ! anatomical row intersection_of: has_member UBERON:7500108 ! cheek tooth relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: has_member UBERON:7500108 ! cheek tooth [Term] id: UBERON:7500115 name: sagittal crest namespace: uberon def: "A ridge or similar projection rising above the surface of an anatomical strucuture along the sagittal (midline) plane." [https://orcid.org/0000-0003-2699-3066] synonym: "sagittal ridge" EXACT [] is_a: UBERON:4200133 ! crest relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500117 name: opisthocranion namespace: uberon def: "A craniometric point which is the furthest point from the glabella along the midline." [https://locatelambda.org/manual/, ISBN:9780873659505, Wiktionary:opisthocranion] comment: In pigs this point is projected into space as a point between a line connecting the aboral points of the right and left superior nuchal lines. {xref="ISBN:9780873659505"} synonym: "opisthokranion" EXACT [ISBN:9780873659505] is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 [Term] id: UBERON:7500119 name: ectorbitale namespace: uberon def: "An anatomical point on the most lateral point of the frontal bone of tetrapods on the occipital side of the orbit." [ISBN:9004086161, ISBN:9789004086166] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0000209 ! tetrapod frontal bone [Term] id: UBERON:7500120 name: zygion namespace: uberon def: "The most lateral anatomical point of the zygomatic arch." [ISBN:9004086161\,9789004086166] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:0006983 ! anatomical point relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0002500 ! zygomatic arch [Term] id: UBERON:7500121 name: paroccipital process namespace: uberon def: "A process of bone extending downward from the jugular process of the occipital bone." [https://medical-dictionary.thefreedictionary.com/paroccipital+process] comment: This process occurs in 0.5-2.0% of the human population. {xref="DOI:10.1016/j.wneu.2018.06.056"} synonym: "estiloid process" EXACT [DOI:10.1016/j.wneu.2018.06.056] synonym: "paracondylar" EXACT [DOI:10.1016/j.wneu.2018.06.056] synonym: "parajugular" EXACT [DOI:10.1016/j.wneu.2018.06.056] synonym: "paramastoid process" EXACT [DOI:10.1016/j.wneu.2018.06.056] synonym: "paraoccipital" EXACT [DOI:10.1016/j.wneu.2018.06.056] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4100000 ! skeletal element projection relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0001676 ! occipital bone [Term] id: UBERON:7500128 name: cranial temporal crest namespace: uberon def: "A ridge or similar projection connected to the temporal lines and nuchal crest on the squamous part of the occipital bone. It bounds the posteroventral part of the temporal fossa." [https://www.researchgate.net/publication/325258124_Morphological_Study_on_the_Skull_of_Wild_Boar_of_Mizoram_Sus_scrofa] synonym: "temporal crest" RELATED [DOI:10.1016/j.asj.2009.01.011] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:4100000 ! skeletal element projection is_a: UBERON:4200133 ! crest intersection_of: UBERON:4200133 ! crest intersection_of: part_of UBERON:0001676 ! occipital bone intersection_of: part_of UBERON:0001678 ! temporal bone relationship: dc-contributor https://orcid.org/0000-0001-8415-4848 relationship: dc-contributor https://orcid.org/0000-0003-2699-3066 relationship: part_of UBERON:0001676 ! occipital bone relationship: part_of UBERON:0001678 ! temporal bone property_value: IAO:0000233 "https://github.com/obophenotype/uberon/issues/2882" xsd:anyURI [Term] id: UBERON:8000006 name: left side of back namespace: uberon def: "Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane." [https://microbiomedb.org/] is_a: UBERON:0001137 ! dorsum is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001137 ! dorsum intersection_of: in_left_side_of UBERON:0000468 ! multicellular organism relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: in_left_side_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:8000007 name: right side of back namespace: uberon def: "Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane." [https://microbiomedb.org/] is_a: UBERON:0001137 ! dorsum is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0001137 ! dorsum intersection_of: in_right_side_of UBERON:0000468 ! multicellular organism relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: in_right_side_of UBERON:0000468 ! multicellular organism [Term] id: UBERON:8000009 name: Purkinje fiber network namespace: uberon def: "A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles." [PMID:26786210] synonym: "Purkinje fibre network" EXACT [PMID:26786210] is_a: UBERON:0010131 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! conducting tissue of heart is_a: UBERON:0018649 ! cardiac muscle tissue of ventricle relationship: dc-contributor https://orcid.org/0000-0001-5208-3432 relationship: has_part UBERON:0002354 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! cardiac Purkinje fiber relationship: part_of UBERON:0004146 {source="https://github.com/obophenotype/uberon/issues/1785", source="https://orcid.org/0000-0001-5208-3432", source="https://orcid.org/0000-0002-9791-0064"} ! His-Purkinje system [Term] id: UBERON:8300001 name: right forelimb namespace: uberon def: "A forelimb that is on the right side of a pectoral complex." [UBERONREF:0000003] xref: FMA:7185 is_a: UBERON:0002102 ! forelimb is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0002102 ! forelimb intersection_of: in_right_side_of UBERON:0010708 ! pectoral complex relationship: dc-contributor https://orcid.org/0000-0001-9897-3238 relationship: in_right_side_of UBERON:0010708 ! pectoral complex property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:8300002 name: left forelimb namespace: uberon def: "A forelimb that is on the left side of a pectoral complex." [UBERONREF:0000003] xref: FMA:7186 is_a: UBERON:0002102 ! forelimb is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0002102 ! forelimb intersection_of: in_left_side_of UBERON:0010708 ! pectoral complex relationship: dc-contributor https://orcid.org/0000-0001-9897-3238 relationship: in_left_side_of UBERON:0010708 ! pectoral complex property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:8300003 name: right hindlimb namespace: uberon def: "A hindlimb that is on the right side of a pelvic complex." [UBERONREF:0000003] xref: FMA:7187 is_a: UBERON:0002103 ! hindlimb is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0002103 ! hindlimb intersection_of: in_right_side_of UBERON:0010709 ! pelvic complex relationship: dc-contributor https://orcid.org/0000-0001-9897-3238 relationship: in_right_side_of UBERON:0010709 ! pelvic complex property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:8300004 name: left hindlimb namespace: uberon def: "A hindlimb that is on the left side of a pelvic complex." [UBERONREF:0000003] xref: FMA:7188 is_a: UBERON:0002103 ! hindlimb is_a: UBERON:0015212 ! lateral structure intersection_of: UBERON:0002103 ! hindlimb intersection_of: in_left_side_of UBERON:0010709 ! pelvic complex relationship: dc-contributor https://orcid.org/0000-0001-9897-3238 relationship: in_left_side_of UBERON:0010709 ! pelvic complex property_value: UBPROP:0000006 "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI [Term] id: UBERON:8400021 name: liver serosa namespace: uberon def: "Hepatic serous coat; peritoneal covering of the liver, enclosing almost all except for a triangular area on its posterior surface (the 'bare area of the liver') and a smaller area where the liver and gallbladder are in direct contact." [https://medical-dictionary.thefreedictionary.com/serosa+of+liver, https://orcid.org/0000-0002-0449-2730] synonym: "serosa of liver" EXACT [FMA:15811] synonym: "tunica serosa hepatis" EXACT [https://medical-dictionary.thefreedictionary.com/serosa+of+liver] {synonymtypedef="LATIN"} is_a: UBERON:0000042 ! serous membrane is_a: UBERON:0000077 ! mixed endoderm/mesoderm-derived structure intersection_of: UBERON:0000042 ! serous membrane intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0002107 ! liver [Term] id: UBERON:8400023 name: liver subserosa namespace: uberon def: "Subserosal tissue of liver. A zone of areolar connective tissue lying beneath the serous coat of the liver and distinguished with difficulty from the fibrous capsule of Glisson." [FMA:15812, https://medical-dictionary.thefreedictionary.com/subserosa+of+liver, https://orcid.org/0000-0002-0449-2730] synonym: "hepatic subserosa" EXACT [] synonym: "subserosal tissue of liver" EXACT [] synonym: "subserous layer of liver" EXACT [] synonym: "tela subserosa (hepar)" EXACT [FMA:15821] synonym: "tela subserosa hepatis" EXACT [https://medical-dictionary.thefreedictionary.com/subserosa+of+liver] is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0012375 ! subserosa intersection_of: UBERON:0012375 ! subserosa intersection_of: part_of UBERON:0002107 ! liver relationship: dc-contributor https://orcid.org/0000-0003-2034-601X relationship: part_of UBERON:0002107 ! liver [Term] id: UBERON:8410001 name: small intestine venule namespace: uberon def: "Venule of villus of small intestine." [https://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "venule of small intestine" EXACT [] is_a: UBERON:0001979 ! venule intersection_of: UBERON:0001979 ! venule intersection_of: part_of UBERON:0001213 ! intestinal villus relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001213 ! intestinal villus [Term] id: UBERON:8410004 name: small intestine arteriole namespace: uberon def: "Arteriole of villus of small intestine." [http://orcid.org/0000-0003-4183-8865] subset: location_grouping synonym: "arteriole of small intestine" EXACT [] synonym: "arteriole of villus of small intestine" EXACT [] synonym: "small intestine villus arteriole" EXACT [] is_a: UBERON:0001980 ! arteriole intersection_of: UBERON:0001980 ! arteriole intersection_of: part_of UBERON:0001213 ! intestinal villus relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001213 ! intestinal villus [Term] id: UBERON:8410008 name: venule of anorectum namespace: uberon def: "A venule that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] synonym: "anorectum venule" EXACT [] is_a: UBERON:0001979 ! venule intersection_of: UBERON:0001979 ! venule intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: UBERON:8410009 name: arteriole of anorectum namespace: uberon def: "An arteriole that is located in the anorectum." [http://orcid.org/0000-0003-3440-1876] synonym: "anorectum arteriole" EXACT [] is_a: UBERON:0001980 ! arteriole intersection_of: UBERON:0001980 ! arteriole intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: UBERON:8410015 name: arteriole of colon namespace: uberon def: "An arteriole located in the colon." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865] is_a: UBERON:0001980 ! arteriole intersection_of: UBERON:0001980 ! arteriole intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001155 ! colon [Term] id: UBERON:8410024 name: intestinal junction namespace: uberon def: "An anatomical junction between two parts of the intestine." [https://orcid.org/0000-0002-7073-9172] synonym: "junction of intestine" EXACT [] is_a: CARO:0000000 ! anatomical entity is_a: UBERON:1100000 ! digestive tract junction intersection_of: UBERON:0007651 ! anatomical junction intersection_of: connects UBERON:0004921 ! subdivision of digestive tract intersection_of: part_of UBERON:0000160 ! intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0000160 ! intestine [Term] id: UBERON:8410043 name: bronchus submucosal gland namespace: uberon def: "A submucosal gland located in a bronchus." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865] subset: human_reference_atlas synonym: "airway submucosal gland" BROAD [] synonym: "bronchial submucosal gland" EXACT [] synonym: "submucosal bronchial gland" EXACT [] synonym: "submucosal bronchus gland" EXACT [] is_a: UBERON:8410077 ! airway submucosal gland intersection_of: UBERON:0011148 ! submucosal gland intersection_of: part_of UBERON:0002185 ! bronchus relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0002185 ! bronchus property_value: RO:0002175 NCBITaxon:9606 [Term] id: UBERON:8410048 name: venule of colon namespace: uberon def: "A venule located in the colon." [https://orcid.org/0000-0003-3440-1876, https://orcid.org/0000-0003-4183-8865] is_a: UBERON:0001979 ! venule intersection_of: UBERON:0001979 ! venule intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001155 ! colon [Term] id: UBERON:8410050 name: anorectum namespace: uberon def: "A subdivision of the digestive tract in humans that includes the rectum, the anal canal and the anus." [DOI:10.1007/978-3-319-26938-2_8, DOI:10.1148/rg.2015150037, http://orcid.org/0000-0002-6826-8770, http://orcid.org/0000-0003-3440-1876, PMID:29742860] synonym: "anorectal canal" NARROW [] is_a: UBERON:0004921 ! subdivision of digestive tract intersection_of: UBERON:0004921 ! subdivision of digestive tract intersection_of: has_part UBERON:0000159 ! anal canal intersection_of: has_part UBERON:0001052 ! rectum intersection_of: has_part UBERON:0001245 ! anus relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: has_part UBERON:0000159 ! anal canal relationship: has_part UBERON:0001052 ! rectum relationship: has_part UBERON:0001245 ! anus relationship: part_of UBERON:0000059 ! large intestine property_value: editor_note "The anatomy, pathology and medical community considers the anus to be part of the large intestine, and supports the use of 'anorectum' to include rectum, anal canal and anus. Although a few resources seem to only include the distal part of the rectum in 'anorectum', this UBERON grouping term is meant to refer more broadly to the whole of rectum." xsd:string property_value: RO:0002175 NCBITaxon:9606 property_value: UBPROP:0000007 "anorectal" xsd:string [Term] id: UBERON:8410056 name: capillary of anorectum namespace: uberon def: "A capillary that is part of the anorectum." [http://orcid.org/0000-0003-3440-1876] synonym: "blood vessel capillary of anorectum" EXACT [] is_a: UBERON:0001982 ! capillary intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:8410050 ! anorectum relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:8410050 ! anorectum [Term] id: UBERON:8410057 name: capillary of colon namespace: uberon def: "A capillary that is part of the colon." [http://orcid.org/0000-0003-3440-1876] synonym: "blood vessel capillary of colon" EXACT [] is_a: UBERON:0001982 ! capillary intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0001155 ! colon relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0001155 ! colon [Term] id: UBERON:8410068 name: capillary of small intestine namespace: uberon def: "A capillary that is part of a small intestine." [http://orcid.org/0000-0003-3440-1876] subset: location_grouping synonym: "blood vessel capillary of small intestine" EXACT [] synonym: "small intestine capillary" EXACT [] is_a: UBERON:0001982 ! capillary intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0002108 ! small intestine relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0002108 ! small intestine property_value: http://purl.org/dc/terms/date "2021-12-21T15:14:31Z" xsd:dateTime [Term] id: UBERON:8410077 name: airway submucosal gland namespace: uberon def: "A submucosal gland found in a respiratory tract." [http://orcid.org/0000-0003-3440-1876, http://orcid.org/0000-0003-4183-8865] synonym: "respiratory tract submucosal gland" EXACT [] synonym: "submucosal gland of respiratory tract" EXACT [] xref: EFO:0010666 is_a: UBERON:0004119 ! endoderm-derived structure is_a: UBERON:0011148 ! submucosal gland is_a: UBERON:0036225 ! respiratory system gland intersection_of: UBERON:0011148 ! submucosal gland intersection_of: part_of UBERON:0000065 ! respiratory tract relationship: dc-contributor https://orcid.org/0000-0002-2825-0621 relationship: part_of UBERON:0000065 ! respiratory tract property_value: http://purl.org/dc/terms/date "2022-03-24T14:21:59Z" xsd:dateTime [Term] id: UBERON:8410080 name: red bone marrow of sternum namespace: uberon def: "Red bone marrow located in the sternum." [http://orcid.org/0000-0001-7655-4833] synonym: "sternum red bone marrow" EXACT [] is_a: UBERON:0000361 ! red bone marrow intersection_of: UBERON:0000361 ! red bone marrow intersection_of: part_of UBERON:0000975 ! sternum relationship: part_of UBERON:0000975 ! sternum created_by: http://orcid.org/0000-0002-2825-0621 [Term] id: UBERON:8410081 name: blood microvessel namespace: uberon def: "Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins." [http://orcid.org/0000-0002-7073-9172, Wikipedia:Microcirculation] synonym: "microvasculature" BROAD [] synonym: "microvessel" BROAD [] is_a: UBERON:0001981 ! blood vessel is_a: UBERON:0010523 ! microcirculatory vessel property_value: seeAlso "https://github.com/obophenotype/uberon/issues/2186" xsd:string property_value: UBPROP:0000007 "microvascular" xsd:string created_by: http://orcid.org/0000-0002-2825-0621 [Term] id: UBERON:8440004 name: laminar subdivision of the cortex namespace: uberon def: "One or a subset of adjacent layers of the neocortex." [ISBN-10:0-87893-742-0] is_a: UBERON:0011215 ! central nervous system cell part cluster relationship: part_of UBERON:0001950 ! neocortex [Term] id: UBERON:8440015 name: noradrenergic cell groups namespace: uberon def: "Collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter norepinephrine (noradrenalin)." [WikipediaVersioned:Noradrenergic_cell_groups&oldid=965992184] is_a: UBERON:0002616 ! regional part of brain relationship: composed_primarily_of CL:0000459 ! noradrenergic cell [Term] id: UBERON:8450002 name: excretory system namespace: uberon def: "An anatomical system that eliminates waste products that arise as a result of metabolic activity." [GO:0007588] is_a: UBERON:0000467 ! anatomical system intersection_of: UBERON:0000467 ! anatomical system intersection_of: capable_of GO:0046903 ! secretion relationship: capable_of GO:0046903 ! secretion created_by: http://orcid.org/0000-0002-6095-8718 creation_date: 2022-05-25T18:21:29Z [Term] id: UBERON:8470000 name: placental blood namespace: uberon def: "Blood located in the placenta." [http://orcid.org/0000-0001-6595-0902, https://www.ncbi.nlm.nih.gov/books/NBK53254/] is_a: UBERON:0000178 ! blood intersection_of: UBERON:0000178 ! blood intersection_of: located_in UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0002-1773-2692 relationship: located_in UBERON:0001987 ! placenta property_value: http://purl.org/dc/terms/date "2022-04-04T11:06:09Z" xsd:dateTime [Term] id: UBERON:8480000 name: iliac vein smooth muscle tissue namespace: uberon def: "A portion of smooth muscle tissue that is part of an iliac vein." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0004696 ! venous system smooth muscle intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005610 ! iliac vein relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0005610 ! iliac vein property_value: http://purl.org/dc/terms/date "2022-06-17T14:34:50Z" xsd:dateTime [Term] id: UBERON:8480001 name: capillary of brain namespace: uberon def: "A capillary that is part of the brain." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0001982 ! capillary is_a: UBERON:0003499 ! brain blood vessel intersection_of: UBERON:0001982 ! capillary intersection_of: part_of UBERON:0000955 ! brain relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 property_value: http://purl.org/dc/terms/date "2022-06-24T09:28:31Z" xsd:dateTime [Term] id: UBERON:8480002 name: thoracic aorta smooth muscle tissue namespace: uberon def: "A portion of smooth muscle tissue that is part of the thoracic aorta." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0004178 ! aorta smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0001515 ! thoracic aorta relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0001515 ! thoracic aorta property_value: http://purl.org/dc/terms/date "2022-06-24T09:30:54Z" xsd:dateTime [Term] id: UBERON:8480003 name: iliac artery smooth muscle tissue namespace: uberon def: "A portion of smooth muscle tissue that is part of an iliac artery." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0002111 ! artery smooth muscle tissue intersection_of: UBERON:0001135 ! smooth muscle tissue intersection_of: part_of UBERON:0005609 ! iliac artery relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0005609 ! iliac artery property_value: http://purl.org/dc/terms/date "2022-06-24T09:32:07Z" xsd:dateTime [Term] id: UBERON:8480004 name: iliac vein endothelium namespace: uberon def: "An endothelium that is part of an iliac vein." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0001919 ! endothelium of vein intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:0005610 ! iliac vein relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0005610 ! iliac vein property_value: http://purl.org/dc/terms/date "2022-06-24T09:33:18Z" xsd:dateTime [Term] id: UBERON:8480005 name: placental artery endothelium namespace: uberon def: "An endothelium that is part of the placental artery." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0001917 ! endothelium of artery is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0005292 ! extraembryonic tissue intersection_of: UBERON:0001986 ! endothelium intersection_of: part_of UBERON:8480007 ! placental artery relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:8480007 ! placental artery property_value: http://purl.org/dc/terms/date "2022-06-24T09:34:25Z" xsd:dateTime [Term] id: UBERON:8480007 name: placental artery namespace: uberon def: "An artery that is part of the placenta." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0001637 ! artery is_a: UBERON:0022358 ! placenta blood vessel intersection_of: UBERON:0001637 ! artery intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 property_value: http://purl.org/dc/terms/date "2022-06-24T11:25:24Z" xsd:dateTime [Term] id: UBERON:8480008 name: placental vein namespace: uberon def: "A vein that is part of the placenta." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0001638 ! vein is_a: UBERON:0022358 ! placenta blood vessel intersection_of: UBERON:0001638 ! vein intersection_of: part_of UBERON:0001987 ! placenta relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 property_value: http://purl.org/dc/terms/date "2022-06-27T09:30:52Z" xsd:dateTime [Term] id: UBERON:8480024 name: skin of sacral region namespace: uberon def: "A zone of skin that is part of the sacral region." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0001415 ! skin of pelvis intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0005473 ! sacral region relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0005473 ! sacral region property_value: http://purl.org/dc/terms/date "2022-08-29T14:14:27Z" xsd:dateTime [Term] id: UBERON:8480025 name: skin of clavicle region namespace: uberon def: "A zone of skin that is above the clavicle zone in the pectoral girdle region." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0000014 ! zone of skin intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0001421 ! pectoral girdle region relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0001421 ! pectoral girdle region property_value: http://purl.org/dc/terms/date "2022-08-29T14:17:12Z" xsd:dateTime [Term] id: UBERON:8480026 name: skin of iliac crest region namespace: uberon def: "A zone of skin that is above the iliac crest in the pelvic girdle bone/zone." [https://orcid.org/0000-0002-0819-0473] synonym: "skin of posterior iliac crest region" BROAD [] is_a: UBERON:0001415 ! skin of pelvis is_a: UBERON:0004120 ! mesoderm-derived structure intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0007830 ! pelvic girdle bone/zone relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0007830 ! pelvic girdle bone/zone property_value: http://purl.org/dc/terms/date "2022-08-29T14:19:16Z" xsd:dateTime [Term] id: UBERON:8480029 name: skin of external genitalia namespace: uberon def: "A zone of skin that is part of the external genitalia." [https://orcid.org/0000-0002-0819-0473] is_a: UBERON:0000014 ! zone of skin is_a: UBERON:0005156 ! reproductive structure intersection_of: UBERON:0000014 ! zone of skin intersection_of: part_of UBERON:0004176 ! external genitalia relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0004176 ! external genitalia property_value: http://purl.org/dc/terms/date "2022-08-30T06:55:06Z" xsd:dateTime [Term] id: UBERON:8480037 name: subserosa of uterine tube namespace: uberon def: "Subserosa that is part of the uterine tube. It contains loose connective tissue, blood vessels and lymphatic tissue." [ISBN:9783662026762, PMID:30095490] synonym: "subserosa of fallopian tube" EXACT [PMID:30095490] synonym: "subserosa of oviduct" EXACT [PMID:34440264] is_a: UBERON:0004120 ! mesoderm-derived structure is_a: UBERON:0005156 ! reproductive structure is_a: UBERON:0012375 ! subserosa intersection_of: UBERON:0012375 ! subserosa intersection_of: part_of UBERON:0003889 ! fallopian tube relationship: dc-contributor https://orcid.org/0000-0002-0819-0473 relationship: part_of UBERON:0003889 ! fallopian tube property_value: http://purl.org/dc/terms/date "2022-10-21T08:55:11Z" xsd:dateTime [Term] id: UBERON:8490000 name: right upper third secondary molar tooth def: "A upper third secondary molar tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 1" EXACT [] synonym: "FDI tooth 18" EXACT [] synonym: "right upper third secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55696] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018577 ! upper third secondary molar tooth intersection_of: UBERON:0018577 ! upper third secondary molar tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490001 name: right upper second secondary molar tooth def: "A upper second secondary molar tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 2" EXACT [] synonym: "FDI tooth 17" EXACT [] synonym: "right upper second secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55697] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018576 ! upper second secondary molar tooth intersection_of: UBERON:0018576 ! upper second secondary molar tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490002 name: right upper first secondary molar tooth def: "A upper first secondary molar tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 3" EXACT [] synonym: "FDI tooth 16" EXACT [] synonym: "right upper first secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55698] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018575 ! upper first secondary molar tooth intersection_of: UBERON:0018575 ! upper first secondary molar tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490003 name: right upper second secondary premolar tooth def: "A upper second secondary premolar tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 4" EXACT [] synonym: "FDI tooth 15" EXACT [] synonym: "right upper second secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55688] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018572 ! upper second secondary premolar tooth intersection_of: UBERON:0018572 ! upper second secondary premolar tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490004 name: right upper first secondary premolar tooth def: "A upper first secondary premolar tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 5" EXACT [] synonym: "FDI tooth 14" EXACT [] synonym: "right upper first secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55689] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018571 ! upper first secondary premolar tooth intersection_of: UBERON:0018571 ! upper first secondary premolar tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490005 name: right upper secondary canine tooth def: "A upper secondary canine tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 6" EXACT [] synonym: "FDI tooth 13" EXACT [] synonym: "right upper secondary canine tooth" EXACT HUMAN_PREFERRED [FMA:55798] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018561 ! upper secondary canine tooth intersection_of: UBERON:0018561 ! upper secondary canine tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490006 name: right upper lateral secondary incisor tooth def: "A upper lateral secondary incisor tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 7" EXACT [] synonym: "FDI tooth 12" EXACT [] synonym: "right upper lateral secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:55680] is_a: UBERON:0016455 ! upper lateral secondary incisor tooth intersection_of: UBERON:0016455 ! upper lateral secondary incisor tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490007 name: right upper central secondary incisor tooth def: "A upper central secondary incisor tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth 8" EXACT [] synonym: "FDI tooth 11" EXACT [] synonym: "right upper central secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:55681] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0016454 ! upper central secondary incisor tooth intersection_of: UBERON:0016454 ! upper central secondary incisor tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490008 name: right lower third secondary molar tooth def: "A lower third secondary molar tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 32" EXACT [] synonym: "FDI tooth 48" EXACT [] synonym: "right lower third secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55707] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018580 ! lower third secondary molar tooth intersection_of: UBERON:0018580 ! lower third secondary molar tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490009 name: right lower second secondary molar tooth def: "A lower second secondary molar tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 31" EXACT [] synonym: "FDI tooth 47" EXACT [] synonym: "right lower second secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55706] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018579 ! lower second secondary molar tooth intersection_of: UBERON:0018579 ! lower second secondary molar tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490010 name: right lower first secondary molar tooth def: "A lower first secondary molar tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 30" EXACT [] synonym: "FDI tooth 46" EXACT [] synonym: "right lower first secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55705] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018578 ! lower first secondary molar tooth intersection_of: UBERON:0018578 ! lower first secondary molar tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490011 name: right lower second secondary premolar tooth def: "A lower second secondary premolar tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 29" EXACT [] synonym: "FDI tooth 45" EXACT [] synonym: "right lower second secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55695] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018574 ! lower second secondary premolar tooth intersection_of: UBERON:0018574 ! lower second secondary premolar tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490012 name: right lower first secondary premolar tooth def: "A lower first secondary premolar tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 28" EXACT [] synonym: "FDI tooth 44" EXACT [] synonym: "right lower first secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55694] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018573 ! lower first secondary premolar tooth intersection_of: UBERON:0018573 ! lower first secondary premolar tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490013 name: right lower secondary canine tooth def: "A lower secondary canine tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 27" EXACT [] synonym: "FDI tooth 43" EXACT [] synonym: "right lower secondary canine tooth" EXACT HUMAN_PREFERRED [FMA:55686] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018562 ! lower secondary canine tooth intersection_of: UBERON:0018562 ! lower secondary canine tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490014 name: right lower lateral secondary incisor tooth def: "A lower lateral secondary incisor tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 26" EXACT [] synonym: "FDI tooth 42" EXACT [] synonym: "right lower lateral secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:57140] is_a: UBERON:0018570 ! lower lateral secondary incisor tooth intersection_of: UBERON:0018570 ! lower lateral secondary incisor tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490015 name: right lower central secondary incisor tooth def: "A lower central secondary incisor tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth 25" EXACT [] synonym: "FDI tooth 41" EXACT [] synonym: "right lower central secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:57142] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018568 ! lower central secondary incisor tooth intersection_of: UBERON:0018568 ! lower central secondary incisor tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490016 name: right upper second primary molar tooth def: "A upper second primary molar tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth A" EXACT [] synonym: "FDI tooth 55" EXACT [] synonym: "right upper second primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84240] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018599 ! upper second primary molar tooth intersection_of: UBERON:0018599 ! upper second primary molar tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490017 name: right upper first primary molar tooth def: "A upper first primary molar tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth B" EXACT [] synonym: "FDI tooth 54" EXACT [] synonym: "right upper first primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84238] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018588 ! upper first primary molar tooth intersection_of: UBERON:0018588 ! upper first primary molar tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490018 name: right upper primary canine tooth def: "A upper primary canine tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth C" EXACT [] synonym: "FDI tooth 53" EXACT [] synonym: "right upper primary canine tooth" EXACT HUMAN_PREFERRED [FMA:84230] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018597 ! upper primary canine tooth intersection_of: UBERON:0018597 ! upper primary canine tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490019 name: right upper lateral primary incisor tooth def: "A upper lateral primary incisor tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth D" EXACT [] synonym: "FDI tooth 52" EXACT [] synonym: "right upper lateral primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84222] is_a: UBERON:0018594 ! upper lateral primary incisor tooth intersection_of: UBERON:0018594 ! upper lateral primary incisor tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490020 name: right upper central primary incisor tooth def: "A upper central primary incisor tooth that is in the right side of the upper jaw region." [] synonym: "ADA tooth E" EXACT [] synonym: "FDI tooth 51" EXACT [] synonym: "right upper central primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84220] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018593 ! upper central primary incisor tooth intersection_of: UBERON:0018593 ! upper central primary incisor tooth intersection_of: in_right_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490021 name: right lower second primary molar tooth def: "A lower second primary molar tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth T" EXACT [] synonym: "FDI tooth 85" EXACT [] synonym: "right lower second primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84244] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018600 ! lower second primary molar tooth intersection_of: UBERON:0018600 ! lower second primary molar tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490022 name: right lower first primary molar tooth def: "A lower first primary molar tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth S" EXACT [] synonym: "FDI tooth 84" EXACT [] synonym: "right lower first primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84242] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018589 ! lower first primary molar tooth intersection_of: UBERON:0018589 ! lower first primary molar tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490023 name: right lower primary canine tooth def: "A lower primary canine tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth R" EXACT [] synonym: "FDI tooth 83" EXACT [] synonym: "right lower primary canine tooth" EXACT HUMAN_PREFERRED [FMA:84232] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018598 ! lower primary canine tooth intersection_of: UBERON:0018598 ! lower primary canine tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490024 name: right lower lateral primary incisor tooth def: "A lower lateral primary incisor tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth Q" EXACT [] synonym: "FDI tooth 82" EXACT [] synonym: "right lower lateral primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84226] is_a: UBERON:0018596 ! lower lateral primary incisor tooth intersection_of: UBERON:0018596 ! lower lateral primary incisor tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490025 name: right lower central primary incisor tooth def: "A lower central primary incisor tooth that is in the right side of the lower jaw region." [] synonym: "ADA tooth P" EXACT [] synonym: "FDI tooth 81" EXACT [] synonym: "right lower central primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84224] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018595 ! lower central primary incisor tooth intersection_of: UBERON:0018595 ! lower central primary incisor tooth intersection_of: in_right_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_right_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-13T00:00:00Z [Term] id: UBERON:8490026 name: left upper third secondary molar tooth def: "A upper third secondary molar tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 16" EXACT [] synonym: "FDI tooth 28" EXACT [] synonym: "left upper third secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55701] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018577 ! upper third secondary molar tooth intersection_of: UBERON:0018577 ! upper third secondary molar tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490027 name: left upper second secondary molar tooth def: "A upper second secondary molar tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 15" EXACT [] synonym: "FDI tooth 27" EXACT [] synonym: "left upper second secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55700] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018576 ! upper second secondary molar tooth intersection_of: UBERON:0018576 ! upper second secondary molar tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490028 name: left upper first secondary molar tooth def: "A upper first secondary molar tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 14" EXACT [] synonym: "FDI tooth 26" EXACT [] synonym: "left upper first secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55699] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018575 ! upper first secondary molar tooth intersection_of: UBERON:0018575 ! upper first secondary molar tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490029 name: left upper second secondary premolar tooth def: "A upper second secondary premolar tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 13" EXACT [] synonym: "FDI tooth 25" EXACT [] synonym: "left upper second secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55691] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018572 ! upper second secondary premolar tooth intersection_of: UBERON:0018572 ! upper second secondary premolar tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490030 name: left upper first secondary premolar tooth def: "A upper first secondary premolar tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 12" EXACT [] synonym: "FDI tooth 24" EXACT [] synonym: "left upper first secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55690] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018571 ! upper first secondary premolar tooth intersection_of: UBERON:0018571 ! upper first secondary premolar tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490031 name: left upper secondary canine tooth def: "A upper secondary canine tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 11" EXACT [] synonym: "FDI tooth 23" EXACT [] synonym: "left upper secondary canine tooth" EXACT HUMAN_PREFERRED [FMA:55799] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018561 ! upper secondary canine tooth intersection_of: UBERON:0018561 ! upper secondary canine tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490032 name: left upper lateral secondary incisor tooth def: "A upper lateral secondary incisor tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 10" EXACT [] synonym: "FDI tooth 22" EXACT [] synonym: "left upper lateral secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:55683] is_a: UBERON:0016455 ! upper lateral secondary incisor tooth intersection_of: UBERON:0016455 ! upper lateral secondary incisor tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490033 name: left upper central secondary incisor tooth def: "A upper central secondary incisor tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth 9" EXACT [] synonym: "FDI tooth 21" EXACT [] synonym: "left upper central secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:55682] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0016454 ! upper central secondary incisor tooth intersection_of: UBERON:0016454 ! upper central secondary incisor tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490034 name: left lower third secondary molar tooth def: "A lower third secondary molar tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 17" EXACT [] synonym: "FDI tooth 38" EXACT [] synonym: "left lower third secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55702] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018580 ! lower third secondary molar tooth intersection_of: UBERON:0018580 ! lower third secondary molar tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490035 name: left lower second secondary molar tooth def: "A lower second secondary molar tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 18" EXACT [] synonym: "FDI tooth 37" EXACT [] synonym: "left lower second secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55703] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018579 ! lower second secondary molar tooth intersection_of: UBERON:0018579 ! lower second secondary molar tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490036 name: left lower first secondary molar tooth def: "A lower first secondary molar tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 19" EXACT [] synonym: "FDI tooth 36" EXACT [] synonym: "left lower first secondary molar tooth" EXACT HUMAN_PREFERRED [FMA:55704] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018578 ! lower first secondary molar tooth intersection_of: UBERON:0018578 ! lower first secondary molar tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490037 name: left lower second secondary premolar tooth def: "A lower second secondary premolar tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 20" EXACT [] synonym: "FDI tooth 35" EXACT [] synonym: "left lower second secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55692] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018574 ! lower second secondary premolar tooth intersection_of: UBERON:0018574 ! lower second secondary premolar tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490038 name: left lower first secondary premolar tooth def: "A lower first secondary premolar tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 21" EXACT [] synonym: "FDI tooth 34" EXACT [] synonym: "left lower first secondary premolar tooth" EXACT HUMAN_PREFERRED [FMA:55693] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018573 ! lower first secondary premolar tooth intersection_of: UBERON:0018573 ! lower first secondary premolar tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490039 name: left lower secondary canine tooth def: "A lower secondary canine tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 22" EXACT [] synonym: "FDI tooth 33" EXACT [] synonym: "left lower secondary canine tooth" EXACT HUMAN_PREFERRED [FMA:55687] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018562 ! lower secondary canine tooth intersection_of: UBERON:0018562 ! lower secondary canine tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490040 name: left lower lateral secondary incisor tooth def: "A lower lateral secondary incisor tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 23" EXACT [] synonym: "FDI tooth 32" EXACT [] synonym: "left lower lateral secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:57141] is_a: UBERON:0018570 ! lower lateral secondary incisor tooth intersection_of: UBERON:0018570 ! lower lateral secondary incisor tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490041 name: left lower central secondary incisor tooth def: "A lower central secondary incisor tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth 24" EXACT [] synonym: "FDI tooth 31" EXACT [] synonym: "left lower central secondary incisor tooth" EXACT HUMAN_PREFERRED [FMA:57143] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018568 ! lower central secondary incisor tooth intersection_of: UBERON:0018568 ! lower central secondary incisor tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490042 name: left upper second primary molar tooth def: "A upper second primary molar tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth J" EXACT [] synonym: "FDI tooth 65" EXACT [] synonym: "left upper second primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84241] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018599 ! upper second primary molar tooth intersection_of: UBERON:0018599 ! upper second primary molar tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490043 name: left upper first primary molar tooth def: "A upper first primary molar tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth I" EXACT [] synonym: "FDI tooth 64" EXACT [] synonym: "left upper first primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84239] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018588 ! upper first primary molar tooth intersection_of: UBERON:0018588 ! upper first primary molar tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490044 name: left upper primary canine tooth def: "A upper primary canine tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth H" EXACT [] synonym: "FDI tooth 63" EXACT [] synonym: "left upper primary canine tooth" EXACT HUMAN_PREFERRED [FMA:84231] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018597 ! upper primary canine tooth intersection_of: UBERON:0018597 ! upper primary canine tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490045 name: left upper lateral primary incisor tooth def: "A upper lateral primary incisor tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth G" EXACT [] synonym: "FDI tooth 62" EXACT [] synonym: "left upper lateral primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84223] is_a: UBERON:0018594 ! upper lateral primary incisor tooth intersection_of: UBERON:0018594 ! upper lateral primary incisor tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490046 name: left upper central primary incisor tooth def: "A upper central primary incisor tooth that is in the left side of the upper jaw region." [] synonym: "ADA tooth F" EXACT [] synonym: "FDI tooth 61" EXACT [] synonym: "left upper central primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84221] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018593 ! upper central primary incisor tooth intersection_of: UBERON:0018593 ! upper central primary incisor tooth intersection_of: in_left_side_of UBERON:0001709 ! upper jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001709 ! upper jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490047 name: left lower second primary molar tooth def: "A lower second primary molar tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth K" EXACT [] synonym: "FDI tooth 75" EXACT [] synonym: "left lower second primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84245] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018600 ! lower second primary molar tooth intersection_of: UBERON:0018600 ! lower second primary molar tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490048 name: left lower first primary molar tooth def: "A lower first primary molar tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth L" EXACT [] synonym: "FDI tooth 74" EXACT [] synonym: "left lower first primary molar tooth" EXACT HUMAN_PREFERRED [FMA:84243] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018589 ! lower first primary molar tooth intersection_of: UBERON:0018589 ! lower first primary molar tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490049 name: left lower primary canine tooth def: "A lower primary canine tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth M" EXACT [] synonym: "FDI tooth 73" EXACT [] synonym: "left lower primary canine tooth" EXACT HUMAN_PREFERRED [FMA:84233] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018598 ! lower primary canine tooth intersection_of: UBERON:0018598 ! lower primary canine tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490050 name: left lower lateral primary incisor tooth def: "A lower lateral primary incisor tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth N" EXACT [] synonym: "FDI tooth 72" EXACT [] synonym: "left lower lateral primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84227] is_a: UBERON:0018596 ! lower lateral primary incisor tooth intersection_of: UBERON:0018596 ! lower lateral primary incisor tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8490051 name: left lower central primary incisor tooth def: "A lower central primary incisor tooth that is in the left side of the lower jaw region." [] synonym: "ADA tooth O" EXACT [] synonym: "FDI tooth 71" EXACT [] synonym: "left lower central primary incisor tooth" EXACT HUMAN_PREFERRED [FMA:84225] is_a: UBERON:0015212 ! lateral structure is_a: UBERON:0018595 ! lower central primary incisor tooth intersection_of: UBERON:0018595 ! lower central primary incisor tooth intersection_of: in_left_side_of UBERON:0001710 ! lower jaw region relationship: dc-contributor https://orcid.org/0000-0001-9625-1899 relationship: in_left_side_of UBERON:0001710 ! lower jaw region property_value: RO:0002175 NCBITaxon:9606 creation_date: 2022-11-18T00:00:00Z [Term] id: UBERON:8600004 name: visceral muscle tissue namespace: uberon def: "A muscle tissue that is associated with soft internal organs (viscera)." [BTO:0002780, CLAO:0001295] comment: It is quite common to refer to visceral muscles as smooth muscles, by analogy with vertebrates; however, most visceral muscles in arthropods are actually striated. {xref="https://en.wikipedia.org/wiki/Smooth_muscle", xref="FBbt:00005070", comment="PMID:8720463"} synonym: "visceral muscle" EXACT [] {comment="BTO:0002780"} is_a: UBERON:0002385 ! muscle tissue relationship: composed_primarily_of CL:0008007 ! visceral muscle cell relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 property_value: http://purl.org/dc/terms/date "2023-02-16T10:17:46Z" xsd:dateTime [Term] id: UBERON:8600006 name: visceral striated muscle tissue namespace: uberon def: "A striated muscle tissue that is associated with soft internal organs (viscera)." [https://pressbooks.pub/rbtallitsch/chapter/chapter-6-muscle-tissue/, PMID:8720463] synonym: "striated visceral muscle tissue" EXACT [] is_a: UBERON:0002036 ! striated muscle tissue is_a: UBERON:8600004 ! visceral muscle tissue relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 property_value: http://purl.org/dc/terms/date "2023-02-16T10:34:43Z" xsd:dateTime [Term] id: UBERON:8600012 name: submucosal gland acinus namespace: uberon def: "A spherical or tubular structure in a submucosal gland that produces and secretes mucus and other substances into the ducts leading to the surface epithelium." [PMID:17394068, PMID:17707699, PMID:25648514, PMID:30864819] is_a: UBERON:0014717 ! mucous acinus intersection_of: UBERON:0009842 ! glandular acinus intersection_of: part_of UBERON:0011148 ! submucosal gland relationship: dc-contributor https://orcid.org/0000-0001-6677-8489 relationship: part_of UBERON:0011148 ! submucosal gland property_value: http://purl.org/dc/terms/date "2023-05-02T08:57:27Z" xsd:dateTime [Term] id: http://purl.org/dc/dcam/VocabularyEncodingScheme is_a: ObsoleteClass ! Obsolete Class property_value: IAO:0000231 IAO:0000103 is_obsolete: true [Term] id: http://rs.tdwg.org/dwc/terms/Event name: Event comment: An action that occurs at some location during some time. is_a: BFO:0000015 ! process property_value: BCO:0000060 "event" xsd:string property_value: IAO:0000112 "A specimen collection process. A camera trap image capture. A marine trawl." xsd:string property_value: isDefinedBy "http://rs.tdwg.org/dwc/terms/" xsd:string [Term] id: http://rs.tdwg.org/dwc/terms/MaterialSample name: Material Sample comment: A physical result of a sampling (or subsampling) event. In biological collections, the material sample is typically collected, and either preserved or destructively processed. is_a: OBI:0100051 ! specimen property_value: BCO:0000060 "specimen" xsd:string property_value: IAO:0000112 "A whole organism preserved in a collection. A part of an organism isolated for some purpose. A soil sample. A marine microbial sample." xsd:string property_value: isDefinedBy "http://rs.tdwg.org/dwc/terms/" xsd:string [Typedef] id: 2D_boundary_of name: 2D boundary of def: "a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity" [] xref: RO:0002000 property_value: editor_note "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts." xsd:string property_value: editor_note "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape." xsd:string property_value: IAO:0000112 "the surface of my skin is a 2D boundary of my body" xsd:string property_value: IAO:0000118 "2D_boundary_of" xsd:string property_value: IAO:0000118 "boundary of" xsd:string property_value: IAO:0000118 "is 2D boundary of" xsd:string property_value: IAO:0000118 "is boundary of" xsd:string property_value: IAO:0000118 "surface of" xsd:string property_value: RO:0001900 RO:0001901 is_a: mereotopologically_related_to ! mereotopologically related to inverse_of: has_boundary ! has 2D boundary [Typedef] id: BFO:0000054 name: realized in comment: Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process property_value: IAO:0000111 "realized in" xsd:string property_value: IAO:0000112 "this disease is realized in this disease course" xsd:string property_value: IAO:0000112 "this fragility is realized in this shattering" xsd:string property_value: IAO:0000112 "this investigator role is realized in this investigation" xsd:string property_value: IAO:0000118 "is realized by" xsd:string property_value: IAO:0000118 "realized_in" xsd:string property_value: IAO:0000600 "[copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl domain: BFO:0000017 ! realizable entity range: BFO:0000015 ! process inverse_of: BFO:0000055 ! realizes [Typedef] id: BFO:0000055 name: realizes comment: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process property_value: IAO:0000111 "realizes" xsd:string property_value: IAO:0000112 "this disease course realizes this disease" xsd:string property_value: IAO:0000112 "this investigation realizes this investigator role" xsd:string property_value: IAO:0000112 "this shattering realizes this fragility" xsd:string property_value: IAO:0000600 "to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/iao.owl domain: BFO:0000015 ! process range: BFO:0000017 ! realizable entity [Typedef] id: BSPO:0001102 name: parallel to namespace: spatial def: "x is parallel t y iff x and y are lines or planes which when extended indefinitely do not cross." [BSPO:curators] [Typedef] id: CL:4030045 name: lacks_part expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" [] [Typedef] id: CL:4030046 name: lacks_plasma_membrane_part expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" [] [Typedef] id: IAO:0000136 name: is about def: "A (currently) primitive relation that relates an information artifact to an entity." [] property_value: editor_note "7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of \"mentions\" relation. Weaken the is_about relationship to be primitive. \n\nWe will try to build it back up by elaborating the various subproperties that are more precisely defined.\n\nSome currently missing phenomena that should be considered \"about\" are predications - \"The only person who knows the answer is sitting beside me\" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic." xsd:string property_value: IAO:0000112 "This document is about information artifacts and their representations" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "person:Alan Ruttenberg" xsd:string property_value: IAO:0000119 "Smith, Ceusters, Ruttenberg, 2000 years of philosophy" xsd:string domain: IAO:0000030 ! information content entity [Typedef] id: OBI:0000293 name: has_specified_input def: "A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of." [] property_value: editor_note "8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works." xsd:string property_value: IAO:0000111 "has_specified_input" xsd:string property_value: IAO:0000111 "has_specified_input" xsd:string property_value: IAO:0000112 "see is_input_of example_of_usage" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Larry Hunter" xsd:string property_value: IAO:0000117 "PERSON: Melanie Coutot" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl domain: OBI:0000011 ! planned process is_a: has_participant ! has participant inverse_of: OBI:0000295 ! is_specified_input_of [Typedef] id: OBI:0000295 name: is_specified_input_of def: "A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of." [] property_value: IAO:0000111 "is_specified_input_of" xsd:string property_value: IAO:0000112 "some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON:Bjoern Peters" xsd:string range: OBI:0000011 ! planned process is_a: participates_in ! participates in [Typedef] id: OBI:0000299 name: has_specified_output def: "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of." [] property_value: IAO:0000111 "has_specified_output" xsd:string property_value: IAO:0000111 "has_specified_output" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "PERSON: Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON: Bjoern Peters" xsd:string property_value: IAO:0000117 "PERSON: Larry Hunter" xsd:string property_value: IAO:0000117 "PERSON: Melanie Courtot" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl domain: OBI:0000011 ! planned process is_a: has_participant ! has participant inverse_of: OBI:0000312 ! is_specified_output_of [Typedef] id: OBI:0000312 name: is_specified_output_of def: "A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of." [] property_value: IAO:0000111 "is_specified_output_of" xsd:string property_value: IAO:0000111 "is_specified_output_of" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "Alan Ruttenberg" xsd:string property_value: IAO:0000117 "PERSON:Bjoern Peters" xsd:string property_value: IAO:0000412 http://purl.obolibrary.org/obo/obi.owl range: OBI:0000011 ! planned process is_a: participates_in ! participates in [Typedef] id: OBI:0000417 name: achieves_planned_objective def: "This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process." [] property_value: IAO:0000111 "achieves_planned_objective" xsd:string property_value: IAO:0000112 "A cell sorting process achieves the objective specification 'material separation objective'" xsd:string property_value: IAO:0000114 IAO:0000120 property_value: IAO:0000117 "BP, AR, PPPB branch" xsd:string property_value: IAO:0000119 "PPPB branch derived" xsd:string property_value: IAO:0000232 "modified according to email thread from 1/23/09 in accordince with DT and PPPB branch" xsd:string domain: OBI:0000011 ! planned process range: IAO:0000005 ! objective specification inverse_of: OBI:0000833 ! objective_achieved_by [Typedef] id: OBI:0000833 name: objective_achieved_by def: "This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process." [] property_value: IAO:0000111 "objective_achieved_by" xsd:string property_value: IAO:0000114 IAO:0000122 property_value: IAO:0000117 "OBI" xsd:string property_value: IAO:0000119 "OBI" xsd:string domain: IAO:0000005 ! objective specification range: OBI:0000011 ! planned process [Typedef] id: RO:0000058 name: is concretized as def: "A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants." [] property_value: IAO:0000112 "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)." xsd:string property_value: IAO:0000112 "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)." xsd:string domain: BFO:0000031 ! generically dependent continuant range: BFO:0000020 ! specifically dependent continuant inverse_of: RO:0000059 ! concretizes [Typedef] id: RO:0000059 name: concretizes def: "A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant." [] property_value: IAO:0000112 "A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant)." xsd:string property_value: IAO:0000112 "An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process)." xsd:string domain: BFO:0000020 ! specifically dependent continuant range: BFO:0000031 ! generically dependent continuant [Typedef] id: acts_on_population_of name: acts on population of namespace: external def: "p acts on population of c iff c' is a collection, has members of type c, and p has participant c" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0012003 is_a: has_participant ! has participant created_by: pg creation_date: 2020-06-08T17:21:33Z [Typedef] id: acts_upstream_of name: acts upstream of def: "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0002263 property_value: IAO:0000112 "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of holds_over_chain: enables causally_upstream_of is_a: acts_upstream_of_or_within ! acts upstream of or within [Typedef] id: acts_upstream_of,_negative_effect name: acts upstream of, negative effect def: "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004035 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004050 RO:0002263 property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of,_negative_effect holds_over_chain: enables causally_upstream_of,_negative_effect is_a: acts_upstream_of ! acts upstream of is_a: acts_upstream_of_or_within,_negative_effect ! acts upstream of or within, negative effect created_by: cjm created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:53:22Z [Typedef] id: acts_upstream_of,_positive_effect name: acts upstream of, positive effect def: "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004034 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004049 RO:0002263 property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of,_positive_effect holds_over_chain: enables causally_upstream_of,_positive_effect is_a: acts_upstream_of ! acts upstream of is_a: acts_upstream_of_or_within,_positive_effect ! acts upstream of or within, positive effect created_by: cjm created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:53:14Z [Typedef] id: acts_upstream_of_or_within name: acts upstream of or within def: "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term synonym: "affects" RELATED [] xref: RO:0002264 property_value: IAO:0000112 "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within holds_over_chain: enables causally_upstream_of_or_within is_a: causal_agent_in_process ! causal agent in process [Typedef] id: acts_upstream_of_or_within,_negative_effect name: acts upstream of or within, negative effect subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004033 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004050 RO:0002264 holds_over_chain: enables causally_upstream_of_or_within,_negative_effect is_a: acts_upstream_of_or_within ! acts upstream of or within created_by: cjm created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:49:51Z [Typedef] id: acts_upstream_of_or_within,_positive_effect name: acts upstream of or within, positive effect subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0004032 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004049 RO:0002264 property_value: seeAlso http://wiki.geneontology.org/index.php/Acts_upstream_of_or_within,_positive_effect holds_over_chain: enables causally_upstream_of_or_within,_positive_effect is_a: acts_upstream_of_or_within ! acts upstream of or within created_by: cjm created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-26T23:49:30Z [Typedef] id: adjacent_to name: adjacent to namespace: external namespace: spatial namespace: uberon def: "x adjacent to y if and only if x and y share a boundary." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002220 property_value: editor_note "This relation acts as a join point with BSPO" xsd:string property_value: IAO:0000112 "A caterpillar walking on the surface of a leaf is adjacent_to the leaf, if one of the caterpillar appendages is touching the leaf. In contrast, a butterfly flying close to a flower is not considered adjacent, unless there are any touching parts." xsd:string {http://www.w3.org/2000/01/rdf-schema#seeAlso="issuecomment-218584934"} property_value: IAO:0000112 "The epidermis layer of a vertebrate is adjacent to the dermis." xsd:string property_value: IAO:0000112 "The plasma membrane of a cell is adjacent to the cytoplasm, and also to the cell lumen which the cytoplasm occupies." xsd:string property_value: IAO:0000112 "The skin of the forelimb is adjacent to the skin of the torso if these are considered anatomical subdivisions with a defined border. Otherwise a relation such as continuous_with would be used." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0001900 RO:0001901 domain: BFO:0000004 ! independent continuant range: BFO:0000004 ! independent continuant is_symmetric: true is_a: spatially_disjoint_from ! spatially disjoint from [Typedef] id: anterior_to name: anterior to namespace: spatial namespace: uberon def: "x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm] synonym: "rostral_to" EXACT [] xref: BSPO:0000096 property_value: seeAlso FBcv:0000039 property_value: seeAlso FBql:00005863 is_transitive: true inverse_of: posterior_to ! posterior to [Typedef] id: anteriorly_connected_to name: anteriorly connected to namespace: uberon def: "x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] is_a: connected_to ! connected to is_a: posterior_to ! posterior to is_a: transitively_anteriorly_connected_to ! transitively anteriorly connected to [Typedef] id: anteriormost_part_of name: anteriormost part of namespace: spatial def: "x anteriormost_part_of y iff x part_of y and there is no z which is part_of y and is more anterior than x but not part_of x; x is adjacent to the anterior boundary of y" [https://orcid.org/0000-0003-2699-3066] xref: BSPO:0030004 property_value: dc-contributor https://orcid.org/0000-0003-2699-3066 is_a: in_anterior_side_of ! in anterior side of [Typedef] id: approximately_perpendicular_to name: approximately perpendicular to namespace: spatial def: "Crosses at an angle that is 90 degrees, or close to 90 degrees. In any non-linear organism, the main axes are rarely perpendicular when taken through the organism as a whole." [BSPO:cjm] xref: BSPO:0000104 domain: BSPO:0000010 ! anatomical axis range: BSPO:0000010 ! anatomical axis [Typedef] id: attaches_to name: attached to namespace: uberon def: "a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a" [] subset: ro-eco xref: RO:0002371 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000589 "attached to (anatomical structure to anatomical structure)" xsd:string is_symmetric: true is_a: attaches_to_part_of ! attached to part of is_a: connected_to ! connected to [Typedef] id: attaches_to_part_of name: attached to part of namespace: uberon def: "a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b." [] xref: RO:0002177 property_value: IAO:0000589 "attached to part of (anatomical structure to anatomical structure)" xsd:string domain: CARO:0000003 ! connected anatomical structure range: CARO:0000003 ! connected anatomical structure holds_over_chain: attaches_to part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} is_a: biomechanically_related_to ! biomechanically related to is_a: mereotopologically_related_to ! mereotopologically related to [Typedef] id: before_or_simultaneous_with name: before or simultaneous with comment: Primitive instance level timing relation between events subset: ro-eco xref: RO:0002081 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000118 "<=" xsd:string is_a: temporally_related_to ! temporally related to [Typedef] id: biomechanically_related_to name: biomechanically related to def: "A relation that holds between elements of a musculoskeletal system or its analogs." [] xref: RO:0002567 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the biomechanical processes." xsd:string domain: CARO:0000003 ! connected anatomical structure range: CARO:0000003 ! connected anatomical structure is_a: functionally_related_to ! functionally related to [Typedef] id: bounding_layer_of name: bounding layer of namespace: external namespace: uberon def: "X outer_layer_of Y iff:\n. X :continuant that bearer_of some PATO:laminar\n. X part_of Y\n. exists Z :surface\n. X has_boundary Z\n. Z boundary_of Y\n\nhas_boundary: http://purl.obolibrary.org/obo/RO_0002002\nboundary_of: http://purl.obolibrary.org/obo/RO_0002000" [] comment: A relationship that applies between a continuant and its outer, bounding layer. Examples include the relationship between a multicellular organism and its integument, between an animal cell and its plasma membrane, and between a membrane bound organelle and its outer/bounding membrane. subset: ro-eco xref: RO:0002007 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 range: BFO:0000040 ! material entity is_a: part_of ! part_of [Typedef] id: branching_part_of name: branching part of namespace: uberon def: "x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y" [] subset: ro-eco xref: RO:0002380 property_value: IAO:0000112 "In the tree T depicted in https://oborel.github.io/obo-relations/branching_part_of.png, B1 is a (direct) branching part of T. B1-1, B1-2, and B1-3 are also branching parts of T, but these are considered indirect branching parts as they do not directly connect to the main stem S" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso "FMA:85994" xsd:string property_value: seeAlso https://github.com/obophenotype/uberon/issues/2212 is_a: in_branching_relationship_with ! in branching relationship with is_a: part_of ! part_of inverse_of: has_branching_part ! has branching part [Typedef] id: capable_of name: capable of namespace: external namespace: uberon def: "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " [] subset: ro-eco xref: RO:0002215 property_value: IAO:0000112 "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)" xsd:string property_value: IAO:0000112 "osteoclast SubClassOf 'capable of' some 'bone resorption'" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has function realized in" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20123131 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/21208450 property_value: IAO:0000232 "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000004 ! independent continuant range: BFO:0000015 ! process is_a: capable_of_part_of ! capable of part of [Typedef] id: capable_of_negatively_regulating name: capable of negatively regulating def: "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." [] xref: RO:0002597 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl holds_over_chain: capable_of negatively_regulates is_a: capable_of_regulating ! capable of regulating [Typedef] id: capable_of_part_of name: capable of part of namespace: external namespace: uberon def: "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." [] xref: RO:0002216 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has function in" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: seeAlso defining-property-chains-involving-reflexivity property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/reflexivity/ holds_over_chain: capable_of part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} is_a: causal_agent_in_process ! causal agent in process is_a: functionally_related_to ! functionally related to [Typedef] id: capable_of_positively_regulating name: capable of positively regulating def: "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." [] xref: RO:0002598 property_value: IAO:0000112 "renin -> arteriolar smooth muscle contraction" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl holds_over_chain: capable_of positively_regulates is_a: capable_of_regulating ! capable of regulating [Typedef] id: capable_of_regulating name: capable of regulating def: "Holds between c and p if and only if c is capable of some activity a, and a regulates p." [] xref: RO:0002596 property_value: IAO:0000112 "pyrethroid -> growth" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl holds_over_chain: capable_of regulates is_a: causal_agent_in_process ! causal agent in process [Typedef] id: causal_agent_in_process name: causal agent in process def: "A relationship between a material entity and a process where the material entity has some causal role that influences the process" [] xref: RO:0002500 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: causal_relation_between_material_entity_and_a_process ! causal relation between material entity and a process inverse_of: process_has_causal_agent ! process has causal agent [Typedef] id: causal_relation_between_entities name: causal relation between entities xref: RO:0002506 property_value: editor_note "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: causally_related_to ! causally related to [Typedef] id: causal_relation_between_material_entity_and_a_process name: causal relation between material entity and a process def: "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." [] xref: RO:0002595 property_value: editor_note "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000040 ! material entity range: BFO:0000015 ! process is_a: causally_related_to ! causally related to [Typedef] id: causal_relation_between_processes name: causal relation between processes def: "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q." [] def: "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." [] xref: RO:0002501 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent is_a: causally_related_to ! causally related to [Typedef] id: causally_downstream_of name: causally downstream of namespace: external def: "inverse of upstream of" [] xref: RO:0002404 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: causally_downstream_of_or_within ! causally downstream of or within is_a: preceded_by ! preceded by inverse_of: causally_upstream_of ! causally upstream of [Typedef] id: causally_downstream_of_or_within name: causally downstream of or within namespace: external def: "inverse of causally upstream of or within" [] subset: RO:0002259 xref: RO:0002427 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_transitive: true is_a: causal_relation_between_processes ! causal relation between processes [Typedef] id: causally_influenced_by name: causally influenced by xref: RO:0002559 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influenced by (entity-centric)" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: causal_relation_between_entities ! causal relation between entities inverse_of: causally_influences ! causally influences [Typedef] id: causally_influences name: causally influences def: "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." [] xref: RO:0002566 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000117 "Vasundra Touré" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "causally influences (entity-centric)" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: causal_relation_between_entities ! causal relation between entities [Typedef] id: causally_related_to name: causally related to def: "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." [https://en.wikipedia.org/wiki/Causality] def: "This relation groups causal relations between material entities and causal relations between processes" [] xref: RO:0002410 property_value: editor_note "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types." xsd:string property_value: editor_note "This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents.\n\nTo define causal relations in an activity-flow type network, we make use of 3 primitives:\n\n * Temporal: how do the intervals of the two occurrents relate? \n * Is the causal relation regulatory?\n * Is the influence positive or negative?\n\nThe first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified.\n\nFor the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule.\n\nFor the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral.\n\nEach of these 3 primitives can be composed to yield a cross-product of different relation types." xsd:string property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl [Typedef] id: causally_upstream_of name: causally upstream of namespace: external def: "p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain" [] def: "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002411 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_transitive: true is_a: causally_upstream_of_or_within ! causally upstream of or within is_a: precedes ! precedes [Typedef] id: causally_upstream_of,_negative_effect name: causally upstream of, negative effect namespace: external def: "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." [] comment: holds between x and y if and only if x is causally upstream of y and the progression of x decreases the frequency, rate or extent of y subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002305 property_value: http://purl.org/dc/terms/creator "cjm" xsd:string property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004050 RO:0002411 is_a: causally_upstream_of ! causally upstream of is_a: causally_upstream_of_or_within,_negative_effect ! causally upstream of or within, negative effect [Typedef] id: causally_upstream_of,_positive_effect name: causally upstream of, positive effect namespace: external def: "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." [] comment: holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002304 property_value: http://purl.org/dc/terms/creator "cjm" xsd:string property_value: http://purl.org/dc/terms/creator https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004049 RO:0002411 is_a: causally_upstream_of ! causally upstream of is_a: causally_upstream_of_or_within,_positive_effect ! causally upstream of or within, positive effect [Typedef] id: causally_upstream_of_or_within name: causally upstream of or within namespace: external def: "p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q." [] def: "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." [] synonym: "affects" RELATED [] xref: RO:0002418 property_value: editor_note "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "influences (processual)" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_transitive: true is_a: causal_relation_between_processes ! causal relation between processes inverse_of: causally_downstream_of_or_within ! causally downstream of or within [Typedef] id: causally_upstream_of_or_within,_negative_effect name: causally upstream of or within, negative effect xref: RO:0004046 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004050 RO:0002418 is_a: causally_upstream_of_or_within ! causally upstream of or within created_by: cjm created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-03-13T23:55:05Z [Typedef] id: causally_upstream_of_or_within,_positive_effect name: causally upstream of or within, positive effect xref: RO:0004047 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004049 RO:0002418 is_a: causally_upstream_of_or_within ! causally upstream of or within created_by: cjm created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-03-13T23:55:19Z [Typedef] id: channel_for name: channel for namespace: uberon synonym: "carries" BROAD [] domain: UBERON:0004111 ! anatomical conduit range: UBERON:0000463 ! organism substance [Typedef] id: channels_from name: channels_from namespace: uberon is_transitive: true [Typedef] id: channels_into name: channels_into namespace: uberon is_transitive: true [Typedef] id: characteristic_of name: characteristic of name: inheres in def: "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence." [] def: "a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence" [] comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing. xref: RO:0000052 property_value: editor_note "A dependent inheres in its bearer at all times for which the dependent exists." xsd:string property_value: IAO:0000111 "inheres in" xsd:string property_value: IAO:0000112 "this fragility inheres in this vase" xsd:string property_value: IAO:0000112 "this fragility is a characteristic of this vase" xsd:string property_value: IAO:0000112 "this red color inheres in this apple" xsd:string property_value: IAO:0000112 "this red color is a characteristic of this apple" xsd:string property_value: IAO:0000118 "inheres_in" xsd:string property_value: RO:0001900 RO:0001901 is_functional: true is_a: characteristic_of_part_of ! characteristic of part of inverse_of: has_characteristic ! bearer of [Typedef] id: characteristic_of_part_of name: characteristic of part of def: "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." [] xref: RO:0002314 property_value: editor_note "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "inheres in part of" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205 property_value: RO:0001900 RO:0001901 property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/reflexivity/ holds_over_chain: characteristic_of part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} is_a: depends_on ! depends on transitive_over: part_of ! part_of [Typedef] id: composed_primarily_of name: composed primarily of namespace: uberon def: "x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y." [] subset: ro-eco xref: RO:0002473 property_value: IAO:0000112 "'otolith organ' SubClassOf 'composed primarily of' some 'calcium carbonate'" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 property_value: RO:0001900 RO:0001901 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: has_part ! has part [Typedef] id: conduit_for name: conduit for namespace: uberon def: "x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x." [] subset: ro-eco xref: RO:0002570 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "UBERON:cjm" xsd:string property_value: IAO:0000232 "This relation holds between a thing with a 'conduit' (e.g. a bone foramen) and a 'conduee' (for example, a nerve) such that at the time the relationship holds, the conduee has two ends sticking out either end of the conduit. It should therefore note be used for objects that move through the conduit but whose spatial extent does not span the passage. For example, it would not be used for a mountain that contains a long tunnel through which trains pass. Nor would we use it for a digestive tract and objects such as food that pass through." xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: overlaps ! overlaps [Typedef] id: confers_advantage_in name: confers advantage in namespace: uberon subset: ro-eco xref: RO:0002322 property_value: editor_note "An experimental relation currently used to connect a feature possessed by an organism (e.g. anatomical structure, biological process, phenotype or quality) to a habitat or environment in which that feature is well suited, adapted or provides a reproductive advantage for the organism. For example, fins to an aquatic environment. Usually this will mean that the structure is adapted for this environment, but we avoid saying this directly - primitive forms of the structure may not have evolved specifically for that environment (for example, early wings were not necessarily adapted for an aerial environment). Note also that this is a statement about the general class of structures - not every instance of a limb need confer an advantage for a terrestrial environment, e.g. if the limb is vestigial." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "adapted for" xsd:string range: ENVO:01000254 is_a: ecologically_related_to ! ecologically related to [Typedef] id: connected_to name: connected to namespace: uberon def: "a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b" [] xref: RO:0002170 property_value: IAO:0000112 "a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones)." xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern" xsd:anyURI is_a: mereotopologically_related_to ! mereotopologically related to [Typedef] id: connects name: connects namespace: uberon def: "c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system." [] xref: RO:0002176 property_value: IAO:0000112 "a 'toe distal phalanx bone' that is connected to a 'toe medial phalanx bone' (an interphalangeal joint *connects* these two bones)." xsd:string property_value: IAO:0000112 "The M8 connects Glasgow and Edinburgh" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Connectivity-Design-Pattern" xsd:anyURI property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-articulations-Design-Pattern" xsd:anyURI domain: BFO:0000004 ! independent continuant is_a: mereotopologically_related_to ! mereotopologically related to [Typedef] id: contained_in name: contained in subset: ro-eco xref: RO:0001018 property_value: editor_note "Containment is location not involving parthood, and arises only where some immaterial continuant is involved." xsd:string property_value: editor_note "Containment obtains in each case between material and immaterial continuants, for instance: lung contained_in thoracic cavity; bladder contained_in pelvic cavity. Hence containment is not a transitive relation. If c part_of c1 at t then we have also, by our definition and by the axioms of mereology applied to spatial regions, c located_in c1 at t. Thus, many examples of instance-level location relations for continuants are in fact cases of instance-level parthood. For material continuants location and parthood coincide. Containment is location not involving parthood, and arises only where some immaterial continuant is involved. To understand this relation, we first define overlap for continuants as follows: c1 overlap c2 at t =def for some c, c part_of c1 at t and c part_of c2 at t. The containment relation on the instance level can then be defined (see definition):" xsd:string property_value: editor_note "Intended meaning:\ndomain: material entity\nrange: spatial region or site (immaterial continuant)\n " xsd:string property_value: IAO:0000111 "contained in" xsd:string property_value: IAO:0000118 "contained_in" xsd:string property_value: RO:0001900 RO:0001901 domain: BFO:0000040 ! material entity range: BFO:0000004 ! independent continuant holds_over_chain: located_in part_of inverse_of: contains ! contains [Typedef] id: contains name: contains namespace: uberon subset: ro-eco xref: RO:0001019 property_value: IAO:0000111 "contains" xsd:string property_value: RO:0001900 RO:0001901 [Typedef] id: contains_process name: contains process namespace: uberon def: "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t" [] comment: Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant xref: BFO:0000067 property_value: IAO:0000111 "site of" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl [Typedef] id: continuous_with name: continuous with namespace: uberon def: "X continuous_with Y if and only if X and Y share a fiat boundary." [] xref: RO:0002150 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "connected to" xsd:string property_value: IAO:0000232 "The label for this relation was previously connected to. I relabeled this to \"continuous with\". The standard notion of connectedness does not imply shared boundaries - e.g. Glasgow connected_to Edinburgh via M8; my patella connected_to my femur (via patellar-femoral joint)" xsd:string property_value: RO:0001900 RO:0001901 property_value: seeAlso "FMA:85972" xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000004 ! independent continuant is_symmetric: true is_a: mereotopologically_related_to ! mereotopologically related to [Typedef] id: contributes_to_morphology_of name: contributes to morphology of namespace: uberon def: "p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm." [] xref: RO:0002433 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: overlaps ! overlaps [Typedef] id: dc-contributor name: contributor namespace: uberon xref: http://purl.org/dc/terms/contributor is_metadata_tag: true [Typedef] id: dc-description name: description namespace: uberon xref: http://purl.org/dc/elements/1.1/description is_metadata_tag: true [Typedef] id: dc-title name: title namespace: uberon xref: http://purl.org/dc/elements/1.1/title is_metadata_tag: true [Typedef] id: dcterms-license name: license namespace: uberon xref: http://purl.org/dc/terms/license is_metadata_tag: true [Typedef] id: deep_to name: deep to namespace: spatial namespace: uberon def: "Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines." [BSPO:cjm] xref: BSPO:0000107 is_transitive: true inverse_of: superficial_to ! superficial to [Typedef] id: depends_on name: depends on xref: RO:0002502 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso BFO:0000169 [Typedef] id: depicted_by name: depicted by namespace: uberon xref: http://xmlns.com/foaf/0.1/depicted_by is_metadata_tag: true [Typedef] id: derived_by_descent_from name: derived by descent from def: "d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a." [] xref: RO:0002156 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "ancestral_stucture_of" xsd:string property_value: IAO:0000118 "evolutionarily_descended_from" xsd:string is_transitive: true is_a: evolutionarily_related_to ! evolutionarily related to inverse_of: has_derived_by_descendant ! has derived by descendant [Typedef] id: derived_from_ancestral_fusion_of name: derived from ancestral fusion of namespace: uberon def: "x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat" [] comment: A has_fused_element B does not imply that A has_part some B: rather than A has_part some B', where B' that has some evolutionary relationship to B. synonym: "has fused element" BROAD [] xref: RO:0002374 property_value: IAO:0000112 "false" xsd:boolean property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 is_a: derived_by_descent_from ! derived by descent from [Typedef] id: developmentally_contributes_to name: developmentally contributes to def: "inverse of has developmental contribution from" [] subset: RO:0002259 xref: RO:0002255 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: develops_into part_of is_a: developmentally_succeeded_by ! developmentally succeeded by is_a: has_potential_to_developmentally_contribute_to ! has potential to developmentally contribute to [Typedef] id: developmentally_induced_by name: developmentally induced by namespace: uberon def: "t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor anatomical structure type T to T', where T' develops_from T" [] def: "t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T" [] xref: RO:0002256 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "induced by" xsd:string property_value: IAO:0000119 " Developmental Biology, Gilbert, 8th edition, figure 6.5(F)" xsd:string property_value: IAO:0000119 "GO:0001759" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205 property_value: IAO:0000232 "We place this under 'developmentally preceded by'. This placement should be examined in the context of reciprocal inductions[cjm]" xsd:string domain: CARO:0000003 ! connected anatomical structure domain: CARO:0000006 ! material anatomical entity range: CARO:0000003 ! connected anatomical structure range: CARO:0000006 ! material anatomical entity is_a: developmentally_preceded_by ! developmentally preceded by inverse_of: developmentally_induces ! developmentally induces [Typedef] id: developmentally_induces name: developmentally induces def: "Inverse of developmentally induced by" [] xref: RO:0002257 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: developmentally_succeeded_by ! developmentally succeeded by is_a: has_potential_to_developmentally_induce ! has potential to developmentally induce [Typedef] id: developmentally_preceded_by name: developmentally preceded by def: "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" [] comment: This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from xref: RO:0002258 property_value: editor_note "false" xsd:boolean property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "In general you should not use this relation to make assertions - use one of the more specific relations below this one" xsd:string domain: BFO:0000002 ! continuant range: BFO:0000002 ! continuant is_a: developmentally_related_to ! developmentally related to inverse_of: developmentally_succeeded_by ! developmentally succeeded by [Typedef] id: developmentally_related_to name: developmentally related to def: "A relationship that holds between entities participating in some developmental process (GO:0032502)" [] xref: RO:0002324 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development" xsd:string [Typedef] id: developmentally_replaces name: developmentally replaces namespace: uberon def: "x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else" [] xref: RO:0002285 property_value: editor_note "This relation is intended for cases such as when we have a bone element replacing its cartilage element precursor. Currently most AOs represent this using 'develops from'. We need to decide whether 'develops from' will be generic and encompass replacement, or whether we need a new name for a generic relation that encompasses replacement and development-via-cell-lineage" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "replaces" xsd:string is_a: developmentally_preceded_by ! developmentally preceded by [Typedef] id: developmentally_succeeded_by name: developmentally succeeded by def: "Inverse of developmentally preceded by" [] xref: RO:0002286 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_developmental_potential_involving ! has developmental potential involving [Typedef] id: develops_from name: develops from namespace: uberon def: "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" [] comment: This is the transitive form of the develops from relation xref: RO:0002202 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 domain: BFO:0000004 ! independent continuant range: BFO:0000004 ! independent continuant is_transitive: true is_a: developmentally_preceded_by ! developmentally preceded by is_a: has_developmental_contribution_from ! has developmental contribution from inverse_of: develops_into ! develops into [Typedef] id: develops_from_part_of name: develops from part of namespace: uberon def: "x develops from part of y if and only if there exists some z such that x develops from z and z is part of y" [] xref: RO:0002225 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: directly_develops_from part_of is_a: develops_from ! develops from [Typedef] id: develops_in name: develops in namespace: uberon def: "x develops_in y if x is located in y whilst x is developing" [] xref: RO:0002226 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "EHDAA2" xsd:string property_value: IAO:0000119 "Jonathan Bard, EHDAA2" xsd:string domain: CARO:0000000 ! anatomical entity holds_over_chain: directly_develops_from located_in is_a: developmentally_preceded_by ! developmentally preceded by [Typedef] id: develops_into name: develops into def: "inverse of develops from" [] subset: RO:0002259 xref: RO:0002203 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000117 https://orcid.org/0000-0003-1980-3228 is_transitive: true is_a: developmentally_succeeded_by ! developmentally succeeded by is_a: has_potential_to_develop_into ! has potential to develop into is_a: has_potential_to_directly_develop_into ! has potential to directly develop into [Typedef] id: device_utilizes_material name: device utilizes material def: "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." [] synonym: "utilizes" BROAD [] xref: RO:0017001 property_value: IAO:0000112 "A diagnostic testing device utilizes a specimen." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0001-9625-1899 property_value: IAO:0000117 https://orcid.org/0000-0003-2620-0345 property_value: IAO:0000232 "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input." xsd:string property_value: IAO:0000232 "See github ticket https://github.com/oborel/obo-relations/issues/497" xsd:string holds_over_chain: capable_of has_input creation_date: 2021-11-08T12:00:00Z [Typedef] id: different_in_magnitude_relative_to name: different in magnitude relative to def: "q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [https://orcid.org/0000-0002-6601-2165] xref: RO:0015006 domain: PATO:0000001 ! quality range: PATO:0000001 ! quality [Typedef] id: directly_develops_from name: directly develops from namespace: uberon def: "Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y." [] comment: TODO - add child relations from DOS synonym: "has developmental precursor" EXACT [] xref: RO:0002207 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000119 "FBbt" xsd:string property_value: RO:0002575 RO:0002202 is_a: develops_from ! develops from inverse_of: directly_develops_into ! directly develops into [Typedef] id: directly_develops_into name: directly develops into def: "inverse of directly develops from" [] subset: RO:0002259 xref: RO:0002210 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000118 "developmental precursor of" xsd:string is_a: develops_into ! develops into [Typedef] id: directly_negatively_regulated_by name: directly negatively regulated by def: "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." [GOC:dos] xref: RO:0002023 is_a: directly_regulated_by ! directly regulated by inverse_of: directly_negatively_regulates ! directly negatively regulates created_by: dos creation_date: 2017-09-17T13:52:38Z [Typedef] id: directly_negatively_regulates name: directly negatively regulates namespace: external def: "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002630 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly negatively regulates (process to process)" xsd:string property_value: RO:0004050 RO:0002578 is_a: directly_regulates ! directly regulates is_a: negatively_regulates ! negatively regulates [Typedef] id: directly_negatively_regulates_activity_of name: directly negatively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B." [] synonym: "molecularly decreases activity of" EXACT [] xref: RO:0002449 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000118 "directly inhibits" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: directly_regulates_activity_of ! directly regulates activity of [Typedef] id: directly_positively_regulated_by name: directly positively regulated by def: "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." [GOC:dos] xref: RO:0002024 is_a: directly_regulated_by ! directly regulated by inverse_of: directly_positively_regulates ! directly positively regulates created_by: dos creation_date: 2017-09-17T13:52:47Z [Typedef] id: directly_positively_regulates name: directly positively regulates namespace: external def: "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002629 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly positively regulates (process to process)" xsd:string property_value: RO:0004049 RO:0002578 is_a: directly_regulates ! directly regulates is_a: positively_regulates ! positively regulates [Typedef] id: directly_positively_regulates_activity_of name: directly positively regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. \nFor example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B." [] synonym: "molecularly increases activity of" EXACT [] xref: RO:0002450 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000118 "directly activates" xsd:string domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: directly_regulates_activity_of ! directly regulates activity of [Typedef] id: directly_regulated_by name: directly regulated by comment: Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2. {xref="GOC:dos"} xref: RO:0002022 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: regulated_by ! regulated by inverse_of: directly_regulates ! directly regulates created_by: dos creation_date: 2017-09-17T13:52:24Z [Typedef] id: directly_regulates name: directly regulates namespace: external def: "p directly regulates q iff p is immediately causally upstream of q and p regulates q." [] def: "Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002578 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "directly regulates (processual)" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0002575 RO:0002211 is_a: immediately_causally_upstream_of ! immediately causally upstream of is_a: regulates ! regulates [Typedef] id: directly_regulates_activity_of name: directly regulates activity of def: "The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.\n\nA and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B." [] synonym: "molecularly controls" EXACT [] xref: RO:0002448 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000117 "Vasundra Touré" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: molecularly_interacts_with ! molecularly interacts with is_a: regulates_activity_of ! regulates activity of [Typedef] id: disposition_of name: disposition of def: "inverse of has disposition" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. subset: RO:0002259 xref: RO:0000092 is_a: characteristic_of ! inheres in [Typedef] id: distal_to name: distal to namespace: spatial namespace: uberon def: "x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal)." [BSPO:cjm] xref: BSPO:0000097 property_value: seeAlso FBcv:0000040 property_value: seeAlso FBql:00005867 is_transitive: true inverse_of: proximal_to ! proximal to [Typedef] id: distally_connected_to name: distally connected to namespace: uberon def: "x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] is_a: connected_to ! connected to is_a: proximal_to ! proximal to is_a: transitively_distally_connected_to ! transitively distally connected to inverse_of: proximally_connected_to ! proximally connected to [Typedef] id: distalmost_part_of name: distalmost part of namespace: spatial namespace: uberon def: "X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y" [https://orcid.org/0000-0002-6601-2165] xref: BSPO:0001108 is_a: in_distal_side_of ! in distal side of [Typedef] id: dorsal_to name: dorsal to namespace: spatial namespace: uberon def: "x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly)." [BSPO:cjm] xref: BSPO:0000098 property_value: seeAlso FBcv:0000041 property_value: seeAlso FBql:00005865 is_transitive: true inverse_of: ventral_to ! ventral to [Typedef] id: dorsalmost_part_of name: dorsalmost part of namespace: spatial def: "x dorsalmost_part_of y iff x part_of y and there is no z which is part_of y and is more dorsal than x but not part_of x; x is adjacent to the dorsal boundary of y" [https://orcid.org/0000-0003-2699-3066] xref: BSPO:0030003 property_value: dc-contributor https://orcid.org/0000-0003-2699-3066 is_a: in_dorsal_side_of ! in dorsal side of [Typedef] id: drains name: drains namespace: uberon def: "Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure." [] xref: RO:0002179 property_value: editor_note "Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between a vein and an anatomical structure" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205 domain: UBERON:0001638 ! vein is_a: connected_to ! connected to [Typedef] id: ecologically_related_to name: ecologically related to def: "A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)" [] subset: ro-eco xref: RO:0002321 property_value: editor_note "Awaiting class for domain/range constraint, see: https://github.com/OBOFoundry/Experimental-OBO-Core/issues/6" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving ecological interactions" xsd:string [Typedef] id: editor_note name: editor note namespace: uberon xref: IAO:0000116 property_value: isDefinedBy http://purl.obolibrary.org/obo/iao.owl is_metadata_tag: true [Typedef] id: enabled_by name: enabled by def: "inverse of enables" [] subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002333 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: functionally_related_to ! functionally related to is_a: has_participant ! has participant [Typedef] id: enables name: enables def: "c enables p iff c is capable of p and c acts to execute p." [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0002327 property_value: IAO:0000112 "a particular instances of akt-2 enables some instance of protein kinase activity" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "catalyzes" xsd:string property_value: IAO:0000118 "executes" xsd:string property_value: IAO:0000118 "has" xsd:string property_value: IAO:0000118 "is catalyzing" xsd:string property_value: IAO:0000118 "is executing" xsd:string property_value: IAO:0000232 "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized." xsd:string property_value: IAO:0000232 "This relation is currently used experimentally by the Gene Ontology Consortium. It may not be stable and may be obsoleted at some future time." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: capable_of ! capable of inverse_of: enabled_by ! enabled by transitive_over: has_component_activity ! has component activity transitive_over: has_part ! has part [Typedef] id: enables_subfunction name: enables subfunction def: "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." [] xref: RO:0004031 holds_over_chain: enables has_part is_a: functionally_related_to ! functionally related to created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-01-25T23:20:13Z [Typedef] id: ends name: ends namespace: uberon def: "inverse of ends with" [] subset: ro-eco xref: RO:0002229 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: part_of ! part_of is_a: temporally_related_to ! temporally related to inverse_of: ends_with ! ends with [Typedef] id: ends_after name: ends after comment: X ends_after Y iff: end(Y) before_or_simultaneous_with end(X) subset: ro-eco xref: RO:0002086 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_transitive: true is_a: temporally_related_to ! temporally related to [Typedef] id: ends_with name: ends with namespace: external namespace: uberon def: "x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: RO:0002230 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "finished by" xsd:string is_transitive: true is_a: has_part ! has part is_a: temporally_related_to ! temporally related to [Typedef] id: evolutionarily_related_to name: evolutionarily related to def: "A relationship that holds via some environmental process" [] xref: RO:0002320 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving the process of evolution." xsd:string [Typedef] id: existence_ends_during name: existence ends during namespace: uberon def: "Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely." [https://orcid.org/0000-0002-6601-2165] def: "x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. synonym: "ceases_to_exist_during" EXACT [] xref: RO:0002492 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during_or_before ! existence ends during or before is_a: existence_overlaps ! existence overlaps transitive_over: part_of ! part_of [Typedef] id: existence_ends_during_or_before name: existence ends during or before namespace: uberon def: "x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002497 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: developmentally_succeeded_by existence_ends_during_or_before holds_over_chain: part_of existence_ends_during_or_before is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage transitive_over: part_of ! part_of transitive_over: precedes ! precedes transitive_over: simultaneous_with ! simultaneous with [Typedef] id: existence_ends_with name: existence ends with namespace: uberon def: "x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002493 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during ! existence ends during [Typedef] id: existence_overlaps name: existence overlaps def: "x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))" [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002490 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage [Typedef] id: existence_starts_and_ends_during name: existence starts and ends during namespace: uberon def: "x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)" [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. synonym: "exists during" EXACT [] xref: RO:0002491 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_ends_during ! existence ends during is_a: existence_starts_during ! existence starts during [Typedef] id: existence_starts_during name: existence starts during namespace: uberon def: "x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y)." [] xref: RO:0002488 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_overlaps ! existence overlaps is_a: existence_starts_during_or_after ! existence starts during or after transitive_over: part_of ! part_of [Typedef] id: existence_starts_during_or_after name: existence starts during or after namespace: uberon def: "x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y)." [] comment: The relations here were created based on work originally by Fabian Neuhaus and David Osumi-Sutherland. The work has not yet been vetted and errors in definitions may have occurred during transcription. xref: RO:0002496 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: developmentally_preceded_by existence_starts_during_or_after holds_over_chain: part_of existence_starts_during_or_after is_a: relation_between_physical_entity_and_a_process_or_stage ! relation between physical entity and a process or stage transitive_over: part_of ! part_of transitive_over: preceded_by ! preceded by transitive_over: simultaneous_with ! simultaneous with [Typedef] id: existence_starts_with name: existence starts with namespace: uberon def: "x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y)." [] xref: RO:0002489 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: existence_starts_during ! existence starts during [Typedef] id: extends_fibers_into name: extends_fibers_into namespace: uberon def: "X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y" [https://orcid.org/0000-0002-7073-9172] is_symmetric: true is_a: connected_to ! connected to [Typedef] id: filtered_through name: filtered through namespace: uberon def: "Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity." [] comment: Relationship between a fluid and a filtration barrier, where the portion of fluid arises as a transformation of another portion of fluid on the other side of the barrier, with larger particles removed [Typedef] id: finishes_axis name: finishes axis namespace: spatial comment: A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. If s finishes axis x, and x has end point p, then x overlaps p xref: BSPO:0015001 domain: BSPO:0000054 ! anatomical side range: BSPO:0000010 ! anatomical axis [Typedef] id: follows_axis name: follows axis namespace: spatial xref: BSPO:0015002 range: BSPO:0000010 ! anatomical axis [Typedef] id: formed_as_result_of name: formed as result of xref: RO:0002354 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: output_of ! output of [Typedef] id: function_of name: function of def: "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. xref: RO:0000079 property_value: editor_note "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists." xsd:string property_value: IAO:0000112 "this catalysis function is a function of this enzyme" xsd:string property_value: IAO:0000118 "function_of" xsd:string property_value: IAO:0000118 "is function of" xsd:string domain: BFO:0000034 ! function is_a: characteristic_of ! inheres in inverse_of: has_function ! has function [Typedef] id: functionally_related_to name: functionally related to namespace: uberon def: "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." [] xref: RO:0002328 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This is a grouping relation that collects relations used for the purpose of connecting structure and function" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl [Typedef] id: has_boundary name: has 2D boundary namespace: uberon def: "a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity" [] xref: RO:0002002 property_value: editor_note "A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts." xsd:string property_value: editor_note "Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape." xsd:string property_value: IAO:0000112 "my body has 2D boundary the surface of my skin" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "has boundary" xsd:string property_value: IAO:0000118 "has_2D_boundary" xsd:string property_value: RO:0001900 RO:0001901 domain: BFO:0000040 ! material entity range: BFO:0000141 ! immaterial entity is_a: mereotopologically_related_to ! mereotopologically related to [Typedef] id: has_branching_part name: has branching part namespace: uberon def: "inverse of branching part of" [] subset: ro-eco subset: RO:0002259 xref: RO:0002569 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_transitive: true is_a: has_part ! has part is_a: in_branching_relationship_with ! in branching relationship with [Typedef] id: has_characteristic name: bearer of name: has characteristic namespace: external def: "a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence" [] def: "Inverse of characteristic_of" [] xref: RO:0000053 property_value: editor_note "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist." xsd:string property_value: IAO:0000111 "bearer of" xsd:string property_value: IAO:0000112 "this apple is bearer of this red color" xsd:string property_value: IAO:0000112 "this vase is bearer of this fragility" xsd:string property_value: IAO:0000118 "bearer_of" xsd:string property_value: IAO:0000118 "is bearer of" xsd:string property_value: RO:0001900 RO:0001901 range: BFO:0000020 ! specifically dependent continuant is_inverse_functional: true [Typedef] id: has_component name: has component namespace: external namespace: uberon def: "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." [] subset: ro-eco xref: RO:0002180 property_value: editor_note "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000232 "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit." xsd:string property_value: RO:0001900 RO:0001901 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:Componency is_a: has_part ! has part [Typedef] id: has_component_activity name: has component activity comment: A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B. xref: RO:0002017 is_a: has_component_process ! has component process created_by: dos creation_date: 2017-05-24T09:44:33Z [Typedef] id: has_component_process name: has component process def: "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." [] xref: RO:0002018 domain: BFO:0000015 ! process range: BFO:0000015 ! process is_a: has_component ! has component created_by: dos creation_date: 2017-05-24T09:49:21Z [Typedef] id: has_cross_section name: has cross section def: "s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2." [https://orcid.org/0000-0002-6601-2165] comment: Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round. xref: RO:0015011 [Typedef] id: has_derived_by_descendant name: has derived by descendant def: "inverse of derived by descent from" [] subset: RO:0002259 xref: RO:0002157 property_value: IAO:0000114 IAO:0000125 is_transitive: true is_a: evolutionarily_related_to ! evolutionarily related to [Typedef] id: has_developmental_contribution_from name: has developmental contribution from namespace: uberon def: "x has developmental contribution from y iff x has some part z such that z develops from y" [] xref: RO:0002254 property_value: IAO:0000112 "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: CARO:0000000 ! anatomical entity range: CARO:0000000 ! anatomical entity holds_over_chain: has_part develops_from is_a: developmentally_preceded_by ! developmentally preceded by inverse_of: developmentally_contributes_to ! developmentally contributes to [Typedef] id: has_developmental_potential_involving name: has developmental potential involving def: "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)." [] xref: RO:0002384 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: CARO:0000000 ! anatomical entity range: CARO:0000000 ! anatomical entity is_a: developmentally_related_to ! developmentally related to [Typedef] id: has_disposition name: has disposition def: "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence" [] xref: RO:0000091 domain: BFO:0000004 ! independent continuant range: BFO:0000016 ! disposition is_a: has_characteristic ! bearer of inverse_of: disposition_of ! disposition of [Typedef] id: has_effector_activity name: has effector activity def: "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity." [GOC:dos] comment: This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations. xref: RO:0002025 is_functional: true is_a: has_component_activity ! has component activity created_by: dos creation_date: 2017-09-22T14:14:36Z [Typedef] id: has_end_location name: has end location namespace: external def: "x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y" [] subset: ro-eco xref: RO:0002232 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "ends with process that occurs in" xsd:string domain: BFO:0000015 ! process range: BFO:0000004 ! independent continuant holds_over_chain: ends_with occurs_in is_a: has_part_that_occurs_in ! has part that occurs in [Typedef] id: has_function name: has function def: "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence" [] xref: RO:0000085 property_value: editor_note "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists." xsd:string property_value: IAO:0000112 "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)" xsd:string property_value: IAO:0000118 "has_function" xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000034 ! function is_a: has_characteristic ! bearer of [Typedef] id: has_input name: has input namespace: external def: "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam subset: ro-eco xref: RO:0002233 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "consumes" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000015 ! process holds_over_chain: starts_with has_input is_a: has_participant ! has participant inverse_of: input_of ! input of [Typedef] id: has_member name: has member namespace: uberon def: "has member is a mereological relation between a collection and an item." [] xref: RO:0002351 property_value: IAO:0000119 "SIO" xsd:string property_value: RO:0001900 RO:0001901 is_a: has_part ! has part [Typedef] id: has_muscle_antagonist name: has muscle antagonist namespace: uberon def: "m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position." [] xref: RO:0002568 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Wikipedia:Antagonist_(muscle)" xsd:string is_a: biomechanically_related_to ! biomechanically related to [Typedef] id: has_muscle_insertion name: has muscle insertion namespace: uberon def: "m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone." [] xref: RO:0002373 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Wikipedia:Insertion_(anatomy)" xsd:string property_value: seeAlso http://dbpedia.org/property/insertion domain: CARO:0000003 {http://purl.obolibrary.org/obo/IAO_0000116="We need to import uberon muscle into RO to use as a stricter domain constraint"} ! connected anatomical structure is_a: attaches_to ! attached to is_a: biomechanically_related_to ! biomechanically related to [Typedef] id: has_muscle_origin name: has muscle origin namespace: uberon def: "m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to." [] xref: RO:0002372 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Wikipedia:Insertion_(anatomy)" xsd:string property_value: seeAlso http://dbpedia.org/property/origin domain: CARO:0000003 {comment="We need to import uberon muscle to create a stricter domain constraint"} ! connected anatomical structure is_a: attaches_to ! attached to is_a: biomechanically_related_to ! biomechanically related to [Typedef] id: has_negative_regulatory_component_activity name: has negative regulatory component activity namespace: external def: "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." [] comment: By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'. xref: RO:0002014 is_a: has_regulatory_component_activity ! has regulatory component activity is_a: negatively_regulated_by ! negatively regulated by created_by: dos creation_date: 2017-05-24T09:31:01Z [Typedef] id: has_output name: has output namespace: external def: "p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam subset: ro-eco xref: RO:0002234 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "produces" xsd:string holds_over_chain: ends_with has_output is_a: has_participant ! has participant inverse_of: output_of ! output of [Typedef] id: has_part name: has part name: has_part namespace: external namespace: quality namespace: spatial namespace: uberon def: "a core relation that holds between a whole and its part" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: BFO:0000051 property_value: editor_note "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part." xsd:string property_value: editor_note "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string property_value: editor_note "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime" xsd:string property_value: editor_note "Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.)\n\nA continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'." xsd:string property_value: IAO:0000111 "has part" xsd:string property_value: IAO:0000112 "my body has part my brain (continuant parthood, two material entities)" xsd:string property_value: IAO:0000112 "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)" xsd:string property_value: IAO:0000112 "this year has part this day (occurrent parthood)" xsd:string property_value: IAO:0000118 "has_part" xsd:string property_value: RO:0001900 RO:0001901 is_transitive: true is_a: overlaps ! overlaps [Typedef] id: has_part_structure_that_is_capable_of name: has part structure that is capable of def: "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" [] xref: RO:0002584 property_value: IAO:0000112 "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: has_part capable_of is_a: causal_relation_between_material_entity_and_a_process ! causal relation between material entity and a process is_a: functionally_related_to ! functionally related to [Typedef] id: has_part_that_occurs_in name: has part that occurs in def: "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." [] subset: ro-eco xref: RO:0002479 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: BFO:0000003 ! occurrent range: BFO:0000004 ! independent continuant holds_over_chain: has_part occurs_in {http://purl.obolibrary.org/obo/RO_0002581="true"} [Typedef] id: has_participant name: has participant namespace: external def: "a relation between a process and a continuant, in which the continuant is somehow involved in the process" [] xref: RO:0000057 property_value: editor_note "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time." xsd:string property_value: http://purl.org/dc/elements/1.1/source "http://www.obofoundry.org/ro/#OBO_REL:has_participant" xsd:string property_value: IAO:0000111 "has participant" xsd:string property_value: IAO:0000112 "this blood coagulation has participant this blood clot" xsd:string property_value: IAO:0000112 "this investigation has participant this investigator" xsd:string property_value: IAO:0000112 "this process has participant this input material (or this output material)" xsd:string property_value: IAO:0000118 "has_participant" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000003 ! occurrent range: BFO:0000002 ! continuant holds_over_chain: has_part has_participant [Typedef] id: has_plasma_membrane_part name: has plasma membrane part def: "Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part." [] xref: RO:0002104 property_value: IAO:0000112 "Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9990-8331 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0003-1617-8244 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/19243617 property_value: RO:0001900 RO:0001901 domain: CARO:0000006 ! material anatomical entity range: CARO:0000006 ! material anatomical entity is_a: has_part ! has part expand_expression_to: "BFO_0000051 some (GO_0005886 and BFO_0000051 some ?Y)" [] [Typedef] id: has_positive_regulatory_component_activity name: has positive regulatory component activity def: "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." [] comment: By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'. xref: RO:0002015 is_a: has_regulatory_component_activity ! has regulatory component activity is_a: positively_regulated_by ! positively regulated by created_by: dos creation_date: 2017-05-24T09:31:17Z [Typedef] id: has_potential_to_develop_into name: has potential to develop into namespace: uberon def: "x has the potential to develop into y iff x develops into y or if x is capable of developing into y" [] xref: RO:0002387 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_developmental_potential_involving ! has developmental potential involving [Typedef] id: has_potential_to_developmentally_contribute_to name: has potential to developmentally contribute to namespace: uberon def: "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y" [] xref: RO:0002385 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_developmental_potential_involving ! has developmental potential involving [Typedef] id: has_potential_to_developmentally_induce name: has potential to developmentally induce def: "x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y" [] xref: RO:0002386 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_developmental_potential_involving ! has developmental potential involving [Typedef] id: has_potential_to_directly_develop_into name: has potential to directly develop into def: "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y" [] xref: RO:0002388 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: has_potential_to_develop_into ! has potential to develop into [Typedef] id: has_primary_input name: has primary input namespace: external def: "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c." [GOC:cjm, GOC:dph, GOC:kva, GOC:pt] {comment="PMID:27812932"} subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0004009 is_a: has_input ! has input is_a: has_primary_input_or_output ! has primary input or output created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-12-13T11:26:56Z [Typedef] id: has_primary_input_or_output name: has primary input or output namespace: external def: "p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c." [] subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0004007 is_a: has_participant ! has participant created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-12-13T11:26:17Z [Typedef] id: has_primary_output name: has primary output namespace: external def: "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c." [GOC:cjm, GOC:dph, GOC:kva, GOC:pt] {comment="PMID:27812932"} subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0004008 is_a: has_output ! has output is_a: has_primary_input_or_output ! has primary input or output created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-12-13T11:26:32Z [Typedef] id: has_quality name: has quality namespace: uberon def: "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence" [] xref: RO:0000086 property_value: editor_note "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist." xsd:string property_value: IAO:0000112 "this apple has quality this red color" xsd:string property_value: IAO:0000118 "has_quality" xsd:string range: BFO:0000019 ! quality is_a: has_characteristic ! bearer of [Typedef] id: has_regulatory_component_activity name: has regulatory component activity namespace: external def: "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." [] xref: RO:0002013 is_a: has_component_activity ! has component activity is_a: regulated_by ! regulated by created_by: dos creation_date: 2017-05-24T09:30:46Z [Typedef] id: has_role name: has role def: "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence" [] xref: RO:0000087 property_value: editor_note "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists." xsd:string property_value: IAO:0000112 "this person has role this investigator role (more colloquially: this person has this role of investigator)" xsd:string property_value: IAO:0000118 "has_role" xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000023 ! role is_a: has_characteristic ! bearer of [Typedef] id: has_skeleton name: has skeleton namespace: uberon def: "A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision." [] xref: RO:0002551 property_value: IAO:0000112 "Forelimb SubClassOf has_skeleton some 'Forelimb skeleton'" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "has supporting framework" xsd:string property_value: IAO:0000232 "The skeleton of a structure may be a true skeleton (for example, the bony skeleton of a hand) or any kind of support framework (the hydrostatic skeleton of a sea star, the exoskeleton of an insect, the cytoskeleton of a cell)." xsd:string domain: CARO:0000003 ! connected anatomical structure domain: UBERON:0000475 ! organism subdivision range: CARO:0000006 {http://purl.obolibrary.org/obo/IAO_0000116="This should be to a more restricted class, but not the Uberon class may be too restricted since it is a composition-based definition of skeleton rather than functional."} ! material anatomical entity range: UBERON:0010912 ! subdivision of skeleton is_a: has_part ! has part inverse_of: skeleton_of ! skeleton of is_asymmetric: true [Typedef] id: has_soma_location name: has soma location def: "Relation between a neuron and an anatomical structure that its soma is part of." [] xref: RO:0002100 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 domain: CL:0000540 ! neuron range: CARO:0000003 ! connected anatomical structure is_a: overlaps ! overlaps transitive_over: part_of ! part_of expand_expression_to: "BFO_0000051 some (\n GO_0043025 and BFO_0000050 some ?Y)" [] [Typedef] id: has_start_location name: has start location namespace: external def: "x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y" [] subset: ro-eco xref: RO:0002231 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "starts with process that occurs in" xsd:string domain: BFO:0000015 ! process range: BFO:0000004 ! independent continuant holds_over_chain: starts_with occurs_in is_a: has_part_that_occurs_in ! has part that occurs in [Typedef] id: has_target_end_location name: has target end location namespace: external def: "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002339 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: results_in_transport_to_from_or_in ! results in transport to from or in transitive_over: part_of ! part_of [Typedef] id: has_target_start_location name: has target start location namespace: external def: "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002338 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: results_in_transport_to_from_or_in ! results in transport to from or in transitive_over: part_of ! part_of [Typedef] id: helper_property_(not_for_use_in_curation) name: helper property (not for use in curation) xref: RO:0002464 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl [Typedef] id: homologous_to name: shares ancestor with namespace: uberon def: "two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a." [] comment: VBO calls this homologous_to xref: RO:0002158 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000232 "Consider obsoleting and merging with child relation, 'in homology relationship with'" xsd:string holds_over_chain: derived_by_descent_from has_derived_by_descendant is_symmetric: true is_transitive: true is_a: evolutionarily_related_to ! evolutionarily related to [Typedef] id: http://purl.org/dc/elements/1.1/contributor namespace: oba is_metadata_tag: true [Typedef] id: immediate_transformation_of name: immediate transformation of namespace: uberon def: "x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t" [] xref: RO:0002495 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0002575 RO:0002494 is_a: directly_develops_from ! directly develops from is_a: transformation_of ! transformation of [Typedef] id: immediately_causally_downstream_of name: immediately causally downstream of namespace: external xref: RO:0002405 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: causally_downstream_of ! causally downstream of is_a: immediately_preceded_by ! immediately preceded by inverse_of: immediately_causally_upstream_of ! immediately causally upstream of [Typedef] id: immediately_causally_upstream_of name: immediately causally upstream of namespace: external def: "p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p must be an input of q." [] def: "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." [] xref: RO:0002412 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0002575 RO:0002411 is_a: causally_upstream_of ! causally upstream of is_a: immediately_precedes ! immediately precedes [Typedef] id: immediately_deep_to name: immediately deep to namespace: spatial namespace: uberon def: "x immediately deep to y iff x deep_to y and x is contiguous with y." [BSPO:curators] xref: BSPO:0001107 is_a: deep_to ! deep to inverse_of: immediately_superficial_to ! immediately superficial to [Typedef] id: immediately_preceded_by name: immediately preceded by namespace: external namespace: uberon comment: X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) xref: RO:0002087 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000118 "starts_at_end_of" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl holds_over_chain: starts_with ends_with is_a: preceded_by ! preceded by inverse_of: immediately_precedes ! immediately precedes [Typedef] id: immediately_precedes name: immediately precedes namespace: external comment: X immediately_precedes_Y iff: end(X) simultaneous_with start(Y) subset: ro-eco xref: RO:0002090 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: IAO:0000118 "ends_at_start_of" xsd:string property_value: IAO:0000118 "meets" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0002575 BFO:0000063 holds_over_chain: ends_with starts_with is_a: precedes ! precedes [Typedef] id: immediately_superficial_to name: immediately superficial to namespace: spatial namespace: uberon def: "x immediately superficial to y iff x superficial to y and x is contiguous with y." [BSPO:curators] xref: BSPO:0015014 property_value: seeAlso https://github.com/obophenotype/uberon/issues/2453 is_a: adjacent_to ! adjacent to is_a: superficial_to ! superficial to [Typedef] id: in_anterior_side_of name: in anterior side of namespace: spatial namespace: uberon def: "X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000123 is_a: part_of ! part_of [Typedef] id: in_branching_relationship_with name: in branching relationship with def: "A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network." [] xref: RO:0002375 property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving branching relationships" xsd:string property_value: IAO:0000232 "This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (plant branches and roots, leaf veins, animal veins, arteries, nerves)" xsd:string property_value: RO:0004036 BFO:0000050 property_value: seeAlso http://purl.obolibrary.org/obo/ro/docs/branching_part_of.png property_value: seeAlso "https://github.com/obophenotype/uberon/issues/170" xsd:anyURI domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: mereotopologically_related_to ! mereotopologically related to [Typedef] id: in_central_side_of name: in central side of namespace: uberon def: "X in_central_side Y <=> if Y is subdivided into left and right portions around some median divisor, all parts of X are closer to the median divisor than the outermost lateral sides." [BSPO:cjm] xref: BSPO:0020001 property_value: dc-contributor https://orcid.org/0000-0002-6523-4866 property_value: editor_note "This was migrated from http://purl.obolibrary.org/obo/uberon/core#in_central_side_of in Uberon." xsd:string property_value: seeAlso BSPO:0000059 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern is_a: part_of ! part_of [Typedef] id: in_distal_side_of name: in distal side of namespace: spatial namespace: uberon def: "x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000125 is_a: part_of ! part_of [Typedef] id: in_dorsal_side_of name: in dorsal side of namespace: spatial namespace: uberon def: "X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion." [BSPO:cjm] xref: BSPO:0015101 is_a: part_of ! part_of [Typedef] id: in_lateral_side_of name: in lateral side of namespace: spatial namespace: uberon def: "X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure" [UBERON:cjm] xref: BSPO:0000126 property_value: seeAlso https://github.com/obophenotype/uberon/issues/2453 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI is_a: part_of ! part_of disjoint_from: in_central_side_of ! in central side of [Typedef] id: in_left_side_of name: in left side of namespace: spatial namespace: uberon def: "X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000120 xref: NCIT:C25229 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI is_a: in_lateral_side_of ! in lateral side of disjoint_from: in_right_side_of ! in right side of [Typedef] id: in_medial_side_of name: in medial side of namespace: spatial def: "X medial side of Y <=> if Y is subdivided into two medial and lateral portions, X is part of the medial portion." [https://orcid.org/0000-0003-2699-3066] xref: BSPO:0030006 property_value: dc-contributor https://orcid.org/0000-0003-2699-3066 is_a: part_of ! part_of [Typedef] id: in_posterior_side_of name: in posterior side of namespace: spatial namespace: uberon def: "X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000122 is_a: part_of ! part_of [Typedef] id: in_proximal_side_of name: in proximal side of namespace: spatial namespace: uberon def: "x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000124 is_a: part_of ! part_of [Typedef] id: in_right_side_of name: in right side of namespace: spatial namespace: uberon def: "X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion." [BSPO:PATO_mtg_2009] xref: BSPO:0000121 xref: NCIT:C25228 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Modeling-paired-structures-Design-Pattern" xsd:anyURI is_a: in_lateral_side_of ! in lateral side of [Typedef] id: in_taxon name: in taxon namespace: uberon def: "x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed." [] comment: Connects a biological entity to its taxon of origin. subset: ro-eco xref: RO:0002162 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9227-417X property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints range: CARO:0001010 ! organism or virus or viroid holds_over_chain: attaches_to in_taxon holds_over_chain: capable_of in_taxon holds_over_chain: connected_to in_taxon holds_over_chain: connects in_taxon holds_over_chain: continuous_with in_taxon holds_over_chain: developmentally_induced_by in_taxon holds_over_chain: develops_from in_taxon holds_over_chain: develops_from_part_of in_taxon holds_over_chain: existence_ends_during in_taxon holds_over_chain: existence_starts_during in_taxon holds_over_chain: extends_fibers_into in_taxon holds_over_chain: has_developmental_contribution_from in_taxon holds_over_chain: has_part in_taxon holds_over_chain: has_potential_to_develop_into in_taxon holds_over_chain: innervated_by in_taxon holds_over_chain: overlaps in_taxon holds_over_chain: part_of in_taxon holds_over_chain: produced_by in_taxon holds_over_chain: produces in_taxon holds_over_chain: results_in_developmental_progression_of in_taxon holds_over_chain: supplies in_taxon is_a: evolutionarily_related_to ! evolutionarily related to [Typedef] id: increased_in_magnitude_relative_to name: increased in magnitude relative to def: "q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale." [https://orcid.org/0000-0002-6601-2165] comment: This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'. xref: RO:0015007 domain: PATO:0000001 ! quality range: PATO:0000001 ! quality is_a: different_in_magnitude_relative_to ! different in magnitude relative to [Typedef] id: indirectly_causally_upstream_of name: indirectly causally upstream of def: "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." [] xref: RO:0012011 is_a: causally_upstream_of ! causally upstream of created_by: pg creation_date: 2022-09-26T06:07:17Z [Typedef] id: indirectly_negatively_regulates name: indirectly negatively regulates def: "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." [] xref: RO:0002409 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "indirectly inhibits" xsd:string property_value: RO:0002579 RO:0002212 holds_over_chain: directly_negatively_regulates directly_negatively_regulates holds_over_chain: directly_negatively_regulates indirectly_negatively_regulates is_transitive: true is_a: indirectly_regulates ! indirectly regulates is_a: negatively_regulates ! negatively regulates transitive_over: directly_negatively_regulates ! directly negatively regulates [Typedef] id: indirectly_positively_regulates name: indirectly positively regulates def: "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." [] xref: RO:0002407 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "indirectly activates" xsd:string property_value: RO:0002579 RO:0002213 holds_over_chain: directly_positively_regulates directly_positively_regulates holds_over_chain: directly_positively_regulates indirectly_positively_regulates holds_over_chain: indirectly_negatively_regulates indirectly_negatively_regulates is_transitive: true is_a: indirectly_regulates ! indirectly regulates is_a: positively_regulates ! positively regulates transitive_over: directly_positively_regulates ! directly positively regulates [Typedef] id: indirectly_regulates name: indirectly regulates def: "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." [] xref: RO:0012012 is_a: indirectly_causally_upstream_of ! indirectly causally upstream of is_a: regulates ! regulates created_by: pg creation_date: 2022-09-26T06:08:01Z [Typedef] id: indirectly_supplies name: indirectly_supplies namespace: uberon def: "a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s." [] property_value: editor_note "add to RO" xsd:string holds_over_chain: has_branching_part indirectly_supplies holds_over_chain: has_branching_part supplies is_transitive: true [Typedef] id: innervated_by name: innervated_by namespace: uberon xref: RO:0002005 property_value: http://purl.org/spar/cito/citesAsAuthority "http://www.ncbi.nlm.nih.gov/pubmed/22402613" xsd:anyURI property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 domain: CARO:0000003 ! connected anatomical structure range: CARO:0001001 ! neuron projection bundle inverse_of: innervates ! innervates transitive_over: branching_part_of ! branching part of [Typedef] id: innervates name: innervates namespace: uberon def: "Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.\nT innervates some R\nExpands_to: T has_fasciculating_neuron_projection that synapse_in some R." [] xref: RO:0002134 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 domain: CARO:0001001 ! neuron projection bundle transitive_over: part_of ! part_of expand_expression_to: "RO_0002132 some (GO_0043005 that (RO_0002131 some (GO_0045202 that BFO_0000050 some Y?)))" [] [Typedef] id: input_of name: input of namespace: uberon def: "inverse of has input" [] subset: ro-eco subset: RO:0002259 xref: RO:0002352 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: functionally_related_to ! functionally related to is_a: participates_in ! participates in [Typedef] id: interaction_relation_helper_property name: interaction relation helper property xref: RO:0002563 property_value: http://xmlns.com/foaf/0.1/page "https://github.com/oborel/obo-relations/wiki/InteractionRelations" xsd:anyURI property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:N-Ary_Relation_Pattern_%28OWL_2%29 property_value: seeAlso "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" xsd:anyURI is_a: helper_property_(not_for_use_in_curation) ! helper property (not for use in curation) [Typedef] id: interacts_with name: interacts with def: "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." [] subset: ro-eco synonym: "in pairwise interaction with" EXACT [] xref: RO:0002434 property_value: closeMatch "http://purl.obolibrary.org/obo/MI_0914" xsd:anyURI property_value: editor_note "Considering relabeling as 'pairwise interacts with'" xsd:anyURI property_value: editor_note "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact." xsd:string property_value: http://xmlns.com/foaf/0.1/page "https://github.com/oborel/obo-relations/wiki/InteractionRelations" xsd:anyURI property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: seeAlso "http://purl.obolibrary.org/obo/MI_0914" xsd:anyURI property_value: seeAlso "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/" xsd:anyURI domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_symmetric: true [Typedef] id: intersects_midsagittal_plane_of name: intersects midsagittal plane of namespace: spatial namespace: uberon def: "X intersects median plane of iff X crosses the midine plane of Y." [] xref: BSPO:0005001 is_a: part_of ! part_of [Typedef] id: involved_in name: involved in def: "c involved_in p if and only if c enables some process p', and p' is part of p" [] xref: RO:0002331 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "actively involved in" xsd:string property_value: IAO:0000118 "enables part of" xsd:string property_value: seeAlso Involved:in holds_over_chain: enables part_of is_a: involved_in_or_involved_in_regulation_of ! involved in or involved in regulation of is_a: participates_in ! participates in transitive_over: part_of ! part_of [Typedef] id: involved_in_negative_regulation_of name: involved in negative regulation of def: "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" [] xref: RO:0002430 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004050 RO:0002428 holds_over_chain: enables negatively_regulates holds_over_chain: involved_in negatively_regulates is_a: involved_in_regulation_of ! involved in regulation of [Typedef] id: involved_in_or_involved_in_regulation_of name: involved in or involved in regulation of def: "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" [] xref: RO:0002431 property_value: editor_note "OWL does not allow defining object properties via a Union" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "involved in or reguates" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: acts_upstream_of_or_within ! acts upstream of or within is_a: causal_agent_in_process ! causal agent in process is_a: functionally_related_to ! functionally related to [Typedef] id: involved_in_positive_regulation_of name: involved in positive regulation of def: "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" [] xref: RO:0002429 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004049 RO:0002428 holds_over_chain: enables positively_regulates holds_over_chain: involved_in positively_regulates is_a: involved_in_regulation_of ! involved in regulation of [Typedef] id: involved_in_regulation_of name: involved in regulation of def: "c involved in regulation of p if c is involved in some p' and p' regulates some p" [] xref: RO:0002428 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl holds_over_chain: enables regulates holds_over_chain: involved_in regulates is_a: acts_upstream_of ! acts upstream of is_a: involved_in_or_involved_in_regulation_of ! involved in or involved in regulation of [Typedef] id: is_active_in name: is active in def: "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure." [GOC:cjm, GOC:dos] synonym: "enables activity in" EXACT [] xref: RO:0002432 property_value: IAO:0000112 "A protein that enables activity in a cytosol." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "executes activity in" xsd:string holds_over_chain: enables occurs_in {http://purl.obolibrary.org/obo/RO_0002581="true"} is_a: functionally_related_to ! functionally related to is_a: overlaps ! overlaps [Typedef] id: is_kinase_activity name: is kinase activity xref: RO:0002481 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: molecular_interaction_relation_helper_property ! molecular interaction relation helper property [Typedef] id: lateralmost_part_of name: lateralmost part of namespace: spatial def: "x lateralmost_part_of y iff x part_of y and there is no z which is part_of y and is more lateral than x but not part_of x; x is adjacent to the lateral boundary of y" [https://orcid.org/0000-0003-2699-3066] xref: BSPO:0030005 property_value: dc-contributor https://orcid.org/0000-0003-2699-3066 is_a: in_lateral_side_of ! in lateral side of [Typedef] id: layer_part_of name: layer part of namespace: uberon is_a: part_of ! part_of [Typedef] id: left_of name: left of namespace: spatial def: "Closer to the left side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is left of some instance y of Y, and there exists some organism o such that x part of o and y part of o." [BSPO:cjm] xref: BSPO:0000110 is_transitive: true inverse_of: right_of ! right of [Typedef] id: located_in name: located in namespace: uberon def: "a relation between two independent continuants, the target and the location, in which the target is entirely within the location" [] subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term xref: RO:0001025 property_value: editor_note "Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus" xsd:string property_value: editor_note "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string property_value: http://purl.org/dc/elements/1.1/source "http://www.obofoundry.org/ro/#OBO_REL:located_in" xsd:string property_value: IAO:0000111 "located in" xsd:string property_value: IAO:0000112 "my brain is located in my head" xsd:string property_value: IAO:0000112 "this rat is located in this cage" xsd:string property_value: IAO:0000118 "located_in" xsd:string property_value: RO:0001900 RO:0001901 domain: BFO:0000004 {http://purl.obolibrary.org/obo/IAO_0000116="This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation."} ! independent continuant range: BFO:0000004 {http://purl.obolibrary.org/obo/IAO_0000116="This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation."} ! independent continuant is_transitive: true transitive_over: part_of ! part_of [Typedef] id: location_of name: location of namespace: uberon def: "a relation between two independent continuants, the location and the target, in which the target is entirely within the location" [] xref: RO:0001015 property_value: editor_note "Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string property_value: IAO:0000111 "is location of" xsd:string property_value: IAO:0000112 "my head is the location of my brain" xsd:string property_value: IAO:0000112 "this cage is the location of this rat" xsd:string property_value: IAO:0000118 "location_of" xsd:string property_value: RO:0001900 RO:0001901 is_transitive: true inverse_of: located_in ! located in [Typedef] id: lumen_of name: lumen of namespace: uberon def: "x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull." [] subset: ro-eco xref: RO:0002571 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:cjm" xsd:string range: BFO:0000040 ! material entity is_a: part_of ! part_of [Typedef] id: luminal_space_of name: luminal space of namespace: uberon def: "s is luminal space of x iff s is lumen_of x and s is an immaterial entity" [] subset: ro-eco xref: RO:0002572 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: BFO:0000141 ! immaterial entity is_a: lumen_of ! lumen of [Typedef] id: medialmost_part_of name: medialmost part of namespace: spatial def: "x medialmost_part_of y iff x part_of y and there is no z which is part_of y and is more medial than x but not part_of x; x is adjacent to the medial boundary of y" [https://orcid.org/0000-0003-2699-3066] xref: BSPO:0030007 property_value: dc-contributor https://orcid.org/0000-0003-2699-3066 is_a: in_medial_side_of ! in medial side of [Typedef] id: member_of name: member of def: "is member of is a mereological relation between a item and a collection." [] xref: RO:0002350 property_value: IAO:0000112 "An organism that is a member of a population of organisms" xsd:string property_value: IAO:0000118 "is member of" xsd:string property_value: IAO:0000118 "member part of" xsd:string property_value: IAO:0000119 "SIO" xsd:string property_value: RO:0001900 RO:0001901 is_a: part_of ! part_of inverse_of: has_member ! has member [Typedef] id: mereotopologically_related_to name: mereotopologically related to def: "A mereological relationship or a topological relationship" [] xref: RO:0002323 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0001900 RO:0001901 [Typedef] id: molecular_interaction_relation_helper_property name: molecular interaction relation helper property xref: RO:0002564 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: interaction_relation_helper_property ! interaction relation helper property [Typedef] id: molecularly_interacts_with name: molecularly interacts with def: "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." [] xref: RO:0002436 property_value: closeMatch "http://purl.obolibrary.org/obo/MI_0915" xsd:anyURI property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "binds" xsd:string property_value: IAO:0000118 "molecularly binds with" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: seeAlso ECO:0000353 property_value: seeAlso "http://purl.obolibrary.org/obo/MI_0915" xsd:anyURI is_symmetric: true is_a: interacts_with ! interacts with [Typedef] id: negatively_regulated_by name: negatively regulated by namespace: external def: "inverse of negatively regulates" [] subset: RO:0002259 xref: RO:0002335 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: regulated_by ! regulated by [Typedef] id: negatively_regulates name: negatively regulates namespace: external def: "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." [] def: "Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002212 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "negatively regulates (process to process)" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004050 RO:0002211 holds_over_chain: ends_with negatively_regulates is_a: causally_upstream_of,_negative_effect ! causally upstream of, negative effect is_a: regulates ! regulates inverse_of: negatively_regulated_by ! negatively regulated by [Typedef] id: negatively_regulates_characteristic name: negatively regulates characteristic namespace: gene_ontology def: "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." [] xref: RO:0019002 property_value: dc-contributor https://orcid.org/0000-0002-8688-6599 holds_over_chain: negatively_regulates positively_regulates_characteristic holds_over_chain: positively_regulates negatively_regulates_characteristic is_a: regulates_characteristic ! regulates characteristic [Typedef] id: occurs_across name: occurs across def: "A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization." [] xref: RO:0002021 is_a: has_part_that_occurs_in ! has part that occurs in created_by: dos creation_date: 2017-07-20T17:19:37Z [Typedef] id: occurs_in name: occurs in namespace: external def: "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t" [] comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: BFO:0000066 property_value: IAO:0000111 "occurs in" xsd:string property_value: IAO:0000118 "occurs_in" xsd:string property_value: IAO:0000118 "unfolds in" xsd:string property_value: IAO:0000118 "unfolds_in" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl domain: BFO:0000003 ! occurrent range: BFO:0000004 ! independent continuant holds_over_chain: part_of occurs_in inverse_of: contains_process ! contains process transitive_over: part_of ! part_of [Typedef] id: only_in_taxon name: only in taxon namespace: uberon def: "x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z." [] xref: RO:0002160 property_value: editor_note "The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.\n\n 'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria" xsd:string property_value: IAO:0000112 "lactation SubClassOf 'only in taxon' some 'Mammalia'" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/17921072 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20973947 property_value: seeAlso https://github.com/obophenotype/uberon/wiki/Taxon-constraints is_a: in_taxon ! in taxon [Typedef] id: opposite_to name: opposite to namespace: spatial def: "Direcly opposite to. i.e. on the opposite side through the axis." [BSPO:cjm] xref: BSPO:0000113 [Typedef] id: orthogonal_to name: orthogonal to namespace: spatial def: "crossing at right angles" [BSPO:cjm] xref: BSPO:0015005 domain: BSPO:0000010 ! anatomical axis range: BSPO:0000400 ! anatomical plane [Typedef] id: output_of name: output of namespace: external namespace: uberon def: "inverse of has output" [] subset: ro-eco subset: RO:0002259 xref: RO:0002353 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: functionally_related_to ! functionally related to is_a: participates_in ! participates in [Typedef] id: overlaps name: overlaps namespace: external namespace: spatial namespace: uberon def: "x overlaps y if and only if there exists some z such that x has part z and z part of y" [] def: "x overlaps y iff they have some part in common." [BSPO:cjm] comment: "(forall (x y) (iff (overlaps x y) (exists (z) (and (part of z x) (part of z y)))))" CLIF [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_gocam subset: ro-eco xref: RO:0002131 property_value: IAO:0000114 IAO:0000125 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0001900 RO:0001901 holds_over_chain: has_part overlaps holds_over_chain: has_part part_of {http://purl.obolibrary.org/obo/RO_0002582="true"} holds_over_chain: part_of part_of is_symmetric: true is_a: mereotopologically_related_to ! mereotopologically related to transitive_over: part_of ! part_of expand_expression_to: "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)" [] [Typedef] id: part_of name: part of name: part_of namespace: external namespace: quality namespace: spatial namespace: uberon def: "a core relation that holds between a part and its whole" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_gp2term subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: BFO:0000050 property_value: editor_note "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other." xsd:string property_value: editor_note "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/" xsd:string property_value: editor_note "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See https://code.google.com/p/obo-relations/wiki/ROAndTime" xsd:string property_value: editor_note "Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.)\n\nA continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'." xsd:string property_value: IAO:0000111 "is part of" xsd:string property_value: IAO:0000112 "my brain is part of my body (continuant parthood, two material entities)" xsd:string property_value: IAO:0000112 "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)" xsd:string property_value: IAO:0000112 "this day is part of this year (occurrent parthood)" xsd:string property_value: IAO:0000118 "part_of" xsd:string property_value: RO:0001900 RO:0001901 property_value: RO:0040042 BFO:0000002 property_value: RO:0040042 BFO:0000003 property_value: RO:0040042 BFO:0000004 property_value: RO:0040042 BFO:0000017 property_value: RO:0040042 BFO:0000019 property_value: RO:0040042 BFO:0000020 property_value: RO:0040042 BFO:0000031 property_value: seeAlso http://ontologydesignpatterns.org/wiki/Community:Parts_and_Collections property_value: seeAlso http://ontologydesignpatterns.org/wiki/Submissions:PartOf property_value: seeAlso "http://www.obofoundry.org/ro/#OBO_REL:part_of" xsd:string is_transitive: true is_a: overlaps ! overlaps inverse_of: has_part ! has part [Typedef] id: part_of_developmental_precursor_of name: part of developmental precursor of xref: RO:0002287 property_value: IAO:0000112 "'hypopharyngeal eminence' SubClassOf 'part of precursor of' some tongue" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 holds_over_chain: part_of directly_develops_into is_a: developmentally_succeeded_by ! developmentally succeeded by [Typedef] id: part_of_structure_that_is_capable_of name: part of structure that is capable of def: "this relation holds between c and p when c is part of some c', and c' is capable of p." [] xref: RO:0002329 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "false" xsd:boolean holds_over_chain: part_of capable_of {http://purl.obolibrary.org/obo/RO_0002581="true"} is_a: functionally_related_to ! functionally related to [Typedef] id: participates_in name: participates in namespace: external namespace: uberon def: "a relation between a continuant and a process, in which the continuant is somehow involved in the process" [] xref: RO:0000056 property_value: IAO:0000111 "participates in" xsd:string property_value: IAO:0000112 "this blood clot participates in this blood coagulation" xsd:string property_value: IAO:0000112 "this input material (or this output material) participates in this process" xsd:string property_value: IAO:0000112 "this investigator participates in this investigation" xsd:string property_value: IAO:0000118 "participates_in" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000002 ! continuant range: BFO:0000003 ! occurrent inverse_of: has_participant ! has participant [Typedef] id: passes_through name: passes through namespace: spatial def: "Intersects at two points." [BSPO:cjm] xref: BSPO:0015006 domain: BSPO:0000010 ! anatomical axis [Typedef] id: phosphorylates name: phosphorylates xref: RO:0002447 property_value: editor_note "Axiomatization to GO to be added later" xsd:string property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: molecularly_interacts_with ! molecularly interacts with [Typedef] id: positively_regulated_by name: positively regulated by namespace: external def: "inverse of positively regulates" [] subset: RO:0002259 xref: RO:0002336 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: regulated_by ! regulated by [Typedef] id: positively_regulates name: positively regulates namespace: external def: "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." [] def: "Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002213 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000589 "positively regulates (process to process)" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl property_value: RO:0004049 RO:0002211 holds_over_chain: ends_with positively_regulates holds_over_chain: negatively_regulates negatively_regulates is_transitive: true is_a: causally_upstream_of,_positive_effect ! causally upstream of, positive effect is_a: regulates ! regulates inverse_of: positively_regulated_by ! positively regulated by [Typedef] id: positively_regulates_characteristic name: positively regulates characteristic namespace: gene_ontology def: "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." [] xref: RO:0019001 property_value: dc-contributor https://orcid.org/0000-0002-8688-6599 holds_over_chain: positively_regulates positively_regulates_characteristic is_a: regulates_characteristic ! regulates characteristic [Typedef] id: postaxialmost_part_of name: postaxialmost part of namespace: spatial namespace: uberon xref: BSPO:0001115 is_a: part_of ! part_of [Typedef] id: posterior_to name: posterior to namespace: spatial namespace: uberon def: "x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail." [BSPO:cjm] synonym: "caudal to" NARROW vertebrate [] xref: BSPO:0000099 property_value: seeAlso FBcv:0000045 property_value: seeAlso FBql:00005864 is_transitive: true [Typedef] id: posteriorly_connected_to name: posteriorly connected to namespace: uberon def: "x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] is_a: anterior_to ! anterior to is_a: connected_to ! connected to [Typedef] id: preaxialmost_part_of name: preaxialmost part of namespace: spatial namespace: uberon xref: BSPO:0001113 is_a: part_of ! part_of [Typedef] id: preceded_by name: preceded by namespace: external namespace: uberon def: "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: BFO:0000062 property_value: editor_note "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other." xsd:string property_value: http://purl.org/dc/elements/1.1/source "http://www.obofoundry.org/ro/#OBO_REL:preceded_by" xsd:string property_value: IAO:0000111 "preceded by" xsd:string property_value: IAO:0000118 "is preceded by" xsd:string property_value: IAO:0000118 "preceded_by" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent holds_over_chain: part_of preceded_by is_transitive: true is_a: ends_after ! ends after inverse_of: precedes ! precedes [Typedef] id: precedes name: precedes namespace: external namespace: uberon def: "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: BFO:0000063 property_value: IAO:0000111 "precedes" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/bfo.owl domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent holds_over_chain: part_of precedes is_transitive: true is_a: temporally_related_to ! temporally related to [Typedef] id: process_has_causal_agent name: process has causal agent namespace: external def: "Inverse of 'causal agent in process'" [] xref: RO:0002608 property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl is_a: causally_related_to ! causally related to [Typedef] id: produced_by name: produced by namespace: external namespace: uberon def: "a produced_by b iff some process that occurs_in b has_output a." [] subset: ro-eco xref: RO:0003001 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity [Typedef] id: produces name: produces namespace: external namespace: uberon def: "a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix." [] comment: Note that this definition doesn't quite distinguish the output of a transformation process from a production process, which is related to the identity/granularity issue. subset: ro-eco xref: RO:0003000 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0001-9114-8737 domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity inverse_of: produced_by ! produced by [Typedef] id: protects name: protects namespace: uberon [Typedef] id: proximal_to name: proximal to namespace: spatial namespace: uberon def: "x proximal to y iff x is closer to the point of attachment with the body than y." [BSPO:cjm] comment: The elbow is proximal to the hand, but distal to the shoulder. xref: BSPO:0000100 xref: NCIT:C25236 property_value: seeAlso FBcv:0000047 property_value: seeAlso FBql:00005868 is_transitive: true [Typedef] id: proximally_connected_to name: proximally connected to namespace: uberon def: "x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] is_a: connected_to ! connected to is_a: distal_to ! distal to is_a: transitively_proximally_connected_to ! transitively proximally connected to [Typedef] id: proximalmost_part_of name: proximalmost part of namespace: spatial namespace: uberon def: "X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y" [https://orcid.org/0000-0002-6601-2165] xref: BSPO:0001106 is_a: in_proximal_side_of ! in proximal side of [Typedef] id: quality_of name: quality of def: "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. xref: RO:0000080 property_value: editor_note "A quality inheres in its bearer at all times for which the quality exists." xsd:string property_value: IAO:0000112 "this red color is a quality of this apple" xsd:string property_value: IAO:0000118 "is quality of" xsd:string property_value: IAO:0000118 "quality_of" xsd:string is_a: characteristic_of ! inheres in inverse_of: has_quality ! has quality [Typedef] id: receives_input_from name: receives input from xref: RO:0002485 property_value: editor_note "See notes for inverse relation" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: connected_to ! connected to inverse_of: sends_output_to ! sends output to [Typedef] id: regulated_by name: regulated by namespace: external def: "inverse of regulates" [] subset: RO:0002259 xref: RO:0002334 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000589 "regulated by (processual)" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000015 ! process range: BFO:0000015 ! process is_transitive: true is_a: causally_downstream_of_or_within ! causally downstream of or within [Typedef] id: regulates name: regulates namespace: external def: "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." [] def: "process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002211 property_value: editor_note "We use 'regulates' here to specifically imply control. However, many colloquial usages of the term correctly correspond to the weaker relation of 'causally upstream of or within' (aka influences). Consider relabeling to make things more explicit" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 "David Hill" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0001-7476-6306 property_value: IAO:0000117 https://orcid.org/0000-0002-3837-8864 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 "Tanya Berardini" xsd:string property_value: IAO:0000119 "GO" xsd:string property_value: IAO:0000119 http://purl.obolibrary.org/obo/ro/docs/causal-relations property_value: IAO:0000232 "Regulation precludes parthood; the regulatory process may not be within the regulated process." xsd:string property_value: IAO:0000589 "regulates (processual)" xsd:string property_value: IAO:0000600 "false" xsd:boolean property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000015 ! process range: BFO:0000015 ! process holds_over_chain: directly_regulates directly_regulates holds_over_chain: ends_with regulates is_transitive: true is_a: causally_upstream_of ! causally upstream of inverse_of: regulated_by ! regulated by transitive_over: has_effector_activity ! has effector activity [Typedef] id: regulates_activity_of name: regulates activity of def: "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." [] xref: RO:0011002 property_value: IAO:0000117 https://orcid.org/0000-0003-4639-4431 property_value: IAO:0000117 "Vasundra Touré" xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000040 ! material entity range: BFO:0000040 ! material entity is_a: causally_influences ! causally influences [Typedef] id: regulates_characteristic name: regulates characteristic namespace: gene_ontology def: "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." [] xref: RO:0019000 property_value: dc-contributor https://orcid.org/0000-0002-8688-6599 domain: BFO:0000015 ! process range: PATO:0000001 ! quality holds_over_chain: regulates regulates_characteristic is_a: causally_related_to ! causally related to [Typedef] id: related_via_localization_to name: related via localization to def: "A relationship that holds via some process of localization" [] xref: RO:0002337 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is a grouping relation." xsd:string domain: BFO:0000015 ! process range: BFO:0000002 ! continuant [Typedef] id: relation_between_physical_entity_and_a_process_or_stage name: relation between physical entity and a process or stage xref: RO:0002487 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, typically connecting an anatomical entity to a biological process or developmental stage." xsd:string domain: BFO:0000004 ! independent continuant range: BFO:0000003 ! occurrent [Typedef] id: results_in_acquisition_of_features_of name: results in acquisition of features of namespace: external def: "The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002315 property_value: IAO:0000112 "an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string range: CARO:0000003 ! connected anatomical structure is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of [Typedef] id: results_in_assembly_of name: results in assembly of namespace: external subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002588 is_a: results_in_formation_of ! results in formation of is_a: results_in_organization_of ! results in organization of [Typedef] id: results_in_breakdown_of name: results in breakdown of def: "p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p" [] xref: RO:0002586 is_a: has_input ! has input [Typedef] id: results_in_changes_to_anatomical_or_cellular_structure name: results in changes to anatomical or cellular structure namespace: external def: "p has anatomical participant c iff p has participant c, and c is an anatomical entity" [] xref: RO:0040036 is_a: has_participant ! has participant created_by: https://orcid.org/0000-0002-6601-2165 creation_date: 2018-09-26T01:08:58Z [Typedef] id: results_in_development_of name: results in development of namespace: external def: "p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002296 property_value: IAO:0000112 "every flower development (GO:0009908) results in development of some flower (PO:0009046)" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "http://www.geneontology.org/GO.doc.development.shtml" xsd:anyURI is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of [Typedef] id: results_in_developmental_progression_of name: results in developmental progression of namespace: external def: "p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." [] def: "p results in the developmental progression of s iff p is a developmental process and s is an anatomical structure and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." [] xref: RO:0002295 property_value: editor_note "This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint." xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: seeAlso Ontology:extensions domain: GO:0008150 ! biological_process range: CARO:0000000 ! anatomical entity range: CARO:0000003 ! connected anatomical structure is_a: developmentally_related_to ! developmentally related to [Typedef] id: results_in_disassembly_of name: results in disassembly of namespace: external xref: RO:0002590 is_a: results_in_breakdown_of ! results in breakdown of is_a: results_in_organization_of ! results in organization of [Typedef] id: results_in_distribution_of name: results in distribution of name: results_in_distribution_of namespace: external xref: GOREL:0002003 [Typedef] id: results_in_fission_of name: results in fission of name: results_in_fission_of namespace: external xref: GOREL:0002004 is_a: has_participant ! has participant [Typedef] id: results_in_formation_of name: results in formation of namespace: external subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002297 property_value: IAO:0000112 "an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists." xsd:string property_value: IAO:0000112 "every \"endocardial cushion formation\" (GO:0003272) results_in_formation_of some \"endocardial cushion\" (UBERON:0002062)" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string is_a: has_output ! has output is_a: results_in_developmental_progression_of ! results in developmental progression of inverse_of: formed_as_result_of ! formed as result of [Typedef] id: results_in_fusion_of name: results in fusion of namespace: external subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0012008 is_a: results_in_organization_of ! results in organization of created_by: pg creation_date: 2021-02-26T07:28:29Z [Typedef] id: results_in_growth_of name: results in growth of namespace: external xref: RO:0002343 property_value: IAO:0000112 "'pollen tube growth' results_in growth_of some 'pollen tube'" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of [Typedef] id: results_in_maturation_of name: results in maturation of namespace: external def: "The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002299 property_value: IAO:0000112 " an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process" xsd:string property_value: IAO:0000112 "bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of [Typedef] id: results_in_morphogenesis_of name: results in morphogenesis of namespace: external def: "The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state." [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002298 property_value: IAO:0000112 "an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape." xsd:string property_value: IAO:0000112 "tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "GOC:mtg_berkeley_2013" xsd:string is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure is_a: results_in_developmental_progression_of ! results in developmental progression of [Typedef] id: results_in_movement_of name: results in movement of namespace: external def: "Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c" [] subset: http://purl.obolibrary.org/obo/valid_for_go_annotation_extension subset: http://purl.obolibrary.org/obo/valid_for_go_ontology subset: http://purl.obolibrary.org/obo/valid_for_gocam xref: RO:0002565 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "" xsd:string is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure [Typedef] id: results_in_organization_of name: results in organization of namespace: external def: "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c" [] xref: RO:0002592 is_a: has_participant ! has participant is_a: results_in_changes_to_anatomical_or_cellular_structure ! results in changes to anatomical or cellular structure [Typedef] id: results_in_transport_across name: results in transport across namespace: external def: "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m." [] subset: http://purl.obolibrary.org/obo/valid_for_go_ontology xref: RO:0002342 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: occurs_across ! occurs across is_a: results_in_transport_to_from_or_in ! results in transport to from or in [Typedef] id: results_in_transport_along name: results in transport along namespace: external def: "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l " [] xref: RO:0002341 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: related_via_localization_to ! related via localization to [Typedef] id: results_in_transport_to_from_or_in name: results in transport to from or in namespace: external xref: RO:0002344 property_value: IAO:0000112 "'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: related_via_localization_to ! related via localization to [Typedef] id: right_of name: right of namespace: spatial def: "Closer to the right side of the organism. Example: The dorsal fin is right of the left pectoral fin, but is left of the right eye. On the type level: X left of Y <=> every instance x of X is right of some instance y of Y, and there exists some organism o such that x part of o and y part of o." [BSPO:cjm] xref: BSPO:0000111 is_transitive: true [Typedef] id: role_of name: role of def: "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence" [] comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020. xref: RO:0000081 property_value: editor_note "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists." xsd:string property_value: IAO:0000112 "this investigator role is a role of this person" xsd:string property_value: IAO:0000118 "is role of" xsd:string property_value: IAO:0000118 "role_of" xsd:string is_a: characteristic_of ! inheres in inverse_of: has_role ! has role [Typedef] id: sends_output_to name: sends output to xref: RO:0002486 property_value: editor_note "This is an exploratory relation. The label is taken from the FMA. It needs aligned with the neuron-specific relations such as has postsynaptic terminal in." xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_a: connected_to ! connected to [Typedef] id: sexually_homologous_to name: sexually_homologous_to namespace: uberon is_a: homologous_to ! shares ancestor with [Typedef] id: simultaneous_with name: simultaneous with namespace: uberon comment: t1 simultaneous_with t2 iff:= t1 before_or_simultaneous_with t2 and not (t1 before t2) subset: ro-eco xref: RO:0002082 property_value: IAO:0000117 "David Osumi-Sutherland" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 is_transitive: true is_a: before_or_simultaneous_with ! before or simultaneous with [Typedef] id: site_of name: site_of namespace: uberon def: "c site_of p if c is the bearer of a disposition that is realized by a process that has p as part." [] synonym: "capable_of_has_part" RELATED [] [Typedef] id: skeleton_of name: skeleton of namespace: uberon def: "inverse of has skeleton" [] subset: RO:0002259 xref: RO:0002576 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 domain: CARO:0000003 ! connected anatomical structure range: CARO:0000003 ! connected anatomical structure is_a: part_of ! part_of [Typedef] id: spatially_coextensive_with name: spatially coextensive with def: "x spatially_coextensive_with y if and inly if x and y have the same location" [] xref: RO:0002379 property_value: IAO:0000112 "A lump of clay and a statue" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000232 "This relation is added for formal completeness. It is unlikely to be used in many practical scenarios" xsd:string is_a: overlaps ! overlaps [Typedef] id: spatially_disjoint_from name: spatially disjoint from def: "A is spatially_disjoint_from B if and only if they have no parts in common" [] subset: ro-eco xref: RO:0002163 property_value: editor_note "There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. " xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/22293552 property_value: IAO:0000232 "Note that it would be possible to use the relation to label the relationship between a near infinite number of structures - between the rings of saturn and my left earlobe. The intent is that this is used for parsiomoniously for disambiguation purposes - for example, between siblings in a jointly exhaustive pairwise disjointness hierarchy" xsd:string property_value: RO:0001900 RO:0001901 property_value: seeAlso "https://github.com/obophenotype/uberon/wiki/Part-disjointness-Design-Pattern" xsd:anyURI is_a: mereotopologically_related_to ! mereotopologically related to expand_expression_to: "BFO_0000051 exactly 0 (BFO_0000050 some ?Y)" [] [Typedef] id: starts name: starts namespace: uberon def: "inverse of starts with" [] subset: ro-eco xref: RO:0002223 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 "Allen" xsd:string is_a: part_of ! part_of is_a: temporally_related_to ! temporally related to inverse_of: starts_with ! starts with [Typedef] id: starts_axis name: starts axis namespace: spatial comment: A directional axis can be divided by a plane. Following Allen Interval Algebra terminology we say that the side on which the axis initiates starts the axis, with the other side finishing the axis. . If s starts axis x, and x has start point p, then x overlaps p xref: BSPO:0015007 domain: BSPO:0000054 ! anatomical side range: BSPO:0000010 ! anatomical axis [Typedef] id: starts_with name: starts with namespace: external namespace: uberon def: "x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point." [] subset: ro-eco xref: RO:0002224 property_value: IAO:0000112 "Every insulin receptor signaling pathway starts with the binding of a ligand to the insulin receptor" xsd:string property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "started by" xsd:string is_transitive: true is_a: has_part ! has part is_a: temporally_related_to ! temporally related to [Typedef] id: subdivision_of name: subdivision of namespace: uberon comment: placeholder relation. X = 'subdivision of A' and subdivision_of some B means that X is the mereological sum of A and B [Typedef] id: superficial_to name: superficial to namespace: spatial namespace: uberon def: "Near the outer surface of the organism. Thus, skin is superficial to the muscle layer." [BSPO:cjm] xref: BSPO:0000108 is_transitive: true [Typedef] id: supplies name: supplies namespace: uberon def: "Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy." [] xref: RO:0002178 property_value: editor_note "Individual ontologies should provide their own constraints on this abstract relation. For example, in the realm of anatomy this should hold between an artery and an anatomical structure" xsd:string property_value: IAO:0000119 http://www.ncbi.nlm.nih.gov/pubmed/20064205 domain: UBERON:0001637 ! artery is_a: connected_to ! connected to [Typedef] id: surface_of name: surface of namespace: spatial comment: placeholder. used for relation between anatomical surface and an anatomical side. xref: BSPO:0015008 domain: BSPO:0000005 ! anatomical surface [Typedef] id: surrounded_by name: surrounded by namespace: uberon def: "x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x" [] xref: RO:0002219 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0001900 RO:0001901 is_a: adjacent_to ! adjacent to inverse_of: surrounds ! surrounds [Typedef] id: surrounds name: surrounds namespace: uberon def: "inverse of surrounded by" [] subset: RO:0002259 xref: RO:0002221 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: RO:0001900 RO:0001901 is_a: adjacent_to ! adjacent to [Typedef] id: synapsed_by name: synapsed by namespace: uberon def: "Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. " [] xref: RO:0002103 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 is_a: receives_input_from ! receives input from inverse_of: synapsed_to ! synapsed to expand_expression_to: "BFO_0000051 some (GO_0045211 that part_of some (GO_0045202 that has_part some (GO_0042734 that BFO_0000050 some Y?)))" [] [Typedef] id: synapsed_to name: synapsed to def: " Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.\n " [] comment: N1 synapsed_to some N2 \nExpands to:\nN1 SubclassOf ( \n has_part some (\n ‘pre-synaptic membrane ; GO:0042734’ that part_of some ( \n ‘synapse ; GO:0045202’ that has_part some (\n ‘post-synaptic membrane ; GO:0045211’ that part_of some N2)))) xref: RO:0002120 property_value: http://purl.org/spar/cito/citesAsAuthority http://www.ncbi.nlm.nih.gov/pubmed/22402613 property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000117 https://orcid.org/0000-0002-7073-9172 property_value: RO:0001900 RO:0001901 is_a: sends_output_to ! sends output to expand_expression_to: "BFO_0000051 some (GO_0042734 that part_of some (GO_0045202 that BFO_0000051 some (GO_0045211 that BFO_0000050 some Y?)))" [] [Typedef] id: temporally_related_to name: temporally related to comment: A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations. subset: ro-eco xref: RO:0002222 property_value: http://purl.org/dc/terms/source "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1" xsd:anyURI property_value: IAO:0000114 IAO:0000125 property_value: IAO:0000117 "Chris Mungall" xsd:string property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000119 https://en.wikipedia.org/wiki/Allen%27s_interval_algebra property_value: IAO:0000232 "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." xsd:string property_value: isDefinedBy http://purl.obolibrary.org/obo/ro.owl domain: BFO:0000003 ! occurrent range: BFO:0000003 ! occurrent [Typedef] id: transformation_of name: transformation of namespace: uberon def: "x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships" [] xref: RO:0002494 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 is_transitive: true is_a: develops_from ! develops from [Typedef] id: transitively_anteriorly_connected_to name: transitively anteriorly connected to namespace: uberon def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] is_transitive: true [Typedef] id: transitively_distally_connected_to name: transitively distally connected to namespace: uberon def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] is_transitive: true [Typedef] id: transitively_proximally_connected_to name: transitively proximally connected to namespace: uberon def: "." [http://purl.obolibrary.org/obo/uberon/docs/Connectivity-Design-Pattern] is_transitive: true [Typedef] id: tributary_of name: tributary of namespace: uberon def: "x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein." [] subset: ro-eco xref: RO:0002376 property_value: IAO:0000112 "Deschutes River tributary_of Columbia River" xsd:string property_value: IAO:0000112 "inferior epigastric vein tributary_of external iliac vein" xsd:string property_value: IAO:0000114 IAO:0000428 property_value: IAO:0000117 https://orcid.org/0000-0002-6601-2165 property_value: IAO:0000118 "drains into" xsd:string property_value: IAO:0000118 "drains to" xsd:string property_value: IAO:0000118 "tributary channel of" xsd:string property_value: IAO:0000119 "http://en.wikipedia.org/wiki/Tributary" xsd:string property_value: IAO:0000119 "http://www.medindia.net/glossary/venous_tributary.htm" xsd:string property_value: IAO:0000232 "This relation can be used for geographic features (e.g. rivers) as well as anatomical structures (veins, arteries)" xsd:anyURI property_value: seeAlso http://dbpedia.org/ontology/drainsTo property_value: seeAlso "http://en.wikipedia.org/wiki/Tributary" xsd:anyURI is_a: connected_to ! connected to is_a: in_branching_relationship_with ! in branching relationship with [Typedef] id: ventral_to name: ventral to namespace: spatial namespace: uberon def: "x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly)." [BSPO:cjm] xref: BSPO:0000102 property_value: seeAlso FBcv:0000049 property_value: seeAlso FBql:00005866 is_transitive: true