in_subset definition database_cross_reference has_alternative_id has_obo_namespace has_exact_synonym has_related_synonym imported from has_narrow_synonym has_broad_synonym part_of occurs in reproduction GO:0000003 GO:0019952 GO:0050876 The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. Wikipedia:Reproduction biological_process reproductive physiological process adaptive immune response An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory). GO:0002250 This term was added by GO_REF:0000022. Wikipedia:Adaptive_immune_system acquired immune response biological_process chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. GO:0005694 Wikipedia:Chromosome cellular_component chromatid interphase chromosome prophase chromosome retrograde vesicle-mediated transport, Golgi to ER GO:0006890 GO:0048220 Reactome:REACT_101581 Reactome:REACT_106254 Reactome:REACT_107028 Reactome:REACT_110794 Reactome:REACT_11208 Reactome:REACT_33374 Reactome:REACT_78144 Reactome:REACT_78992 Reactome:REACT_79320 Reactome:REACT_84617 Reactome:REACT_84887 Reactome:REACT_86027 Reactome:REACT_86772 Reactome:REACT_87591 Reactome:REACT_88478 Reactome:REACT_88525 Reactome:REACT_92195 Reactome:REACT_92336 The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG. biological_process cis-Golgi to rough ER transport cis-Golgi to rough ER vesicle-mediated transport cis-Golgi to rough endoplasmic reticulum transport cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport retrograde (Golgi to ER) transport retrograde transport, Golgi to ER retrograde transport, Golgi to endoplasmic reticulum retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. GO:0006955 This term was improved by GO_REF:0000022. It was redefined and moved. biological_process tRNA processing GO:0008033 The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group. biological_process tRNA maturation biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. GO:0000004 GO:0007582 GO:0008150 Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. Note that when this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this. Wikipedia:Biological_process biological process biological process unknown biological_process physiological process metabolic process GO:0008152 Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. Wikipedia:Metabolism biological_process metabolic process resulting in cell growth metabolism metabolism resulting in cell growth cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo. GO:0008219 accidental cell death biological_process necrosis entry into host cell GO:0030260 Reactome:REACT_6903 The invasion by an organism of a cell of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. biological_process host cell invasion macromolecular complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. GO:0032991 cellular_component macromolecule complex entry of bacterium into host cell 2011-01-13T02:26:54Z GO:0035635 The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction. bacterial entry into host cell biological_process invasion of bacteria into host cell rfoulger growth GO:0040007 GO:0048590 See also the biological process term 'cell growth ; GO:0016049'. The increase in size or mass of an entire organism, a part of an organism or a cell. biological_process growth pattern non-developmental growth entry into host GO:0044409 Penetration by an organism into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. biological_process host invasion invasion into host invasion of host invasive growth interspecies interaction between organisms Any process in which an organism has an effect on an organism of a different species. GO:0044419 biological_process interaction with another species interspecies interaction interspecies interaction with other organisms intracellular transport GO:0046907 The directed movement of substances within a cell. biological_process establishment of localization GO:0051234 The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location. biological_process establishment of localisation establishment of localization in cell GO:0051649 The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell. biological_process establishment of cellular localization establishment of intracellular localization establishment of localisation in cell establishment of localization within cell positioning within cell multi-organism process A biological process which involves another organism of the same or different species. GO:0051704 GO:0051706 biological_process interaction between organisms physiological interaction between organisms physiological interaction with other organism nitric-oxide synthase biosynthetic process GO:0051767 GO:0051768 NO synthase biosynthesis NO synthase biosynthetic process NOS biosynthesis NOS biosynthetic process NOS1 biosynthesis NOS2 biosynthesis NOS2 synthase biosynthesis NOS2 synthase biosynthetic process NOS3 biosynthesis The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+. biological_process brain nitric-oxide synthase biosynthetic process endothelial nitric-oxide synthase biosynthetic process inducible nitric-oxide synthase biosynthetic process nitric-oxide synthase (type 2) biosynthesis nitric-oxide synthase (type 2) biosynthetic process nitric-oxide synthase (type II) biosynthesis nitric-oxide synthase (type II) biosynthetic process nitric-oxide synthase 2 biosynthetic process nitric-oxide synthase-1 biosynthetic process nitric-oxide synthase-2 biosynthetic process nitric-oxide synthase-3 biosynthetic process quorum sensing involved in interaction with host GO:0052106 The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction. biological_process quorum sensing during interaction with host biological regulation Any process that modulates a measurable attribute of any biological process, quality or function. GO:0065007 biological_process regulation reactive oxygen species metabolic process 2011-02-11T10:50:06Z GO:0072593 ROS metabolic process The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. biological_process midori reactive oxygen species metabolism phagosome maturation 2010-10-19T11:10:34Z A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome. GO:0090382 biological_process tanyaberardini phagosome acidification 2010-10-27T10:20:22Z Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion. GO:0090383 biological_process phagosomal acidification tanyaberardini phagosome-lysosome fusion 2010-10-27T10:24:28Z GO:0090385 The creation of a phagolysosome from a phagosome and a lysosome. biological_process tanyaberardini