format-version: 1.2
date: 05:02:2021 13:48
saved-by: fbb
default-namespace: mouse_stages_ontology
subsetdef: granular_stage "Subset consisting of classes describing highly granular developmental stages (for instance, '23-year-old'). Such stages might be useful for annotation purpose, but might be folded into less granular parents for display purpose."
ontology: mmusdv
property_value: IAO:0000700 MmusDv:0000090

[Term]
id: MmusDv:0000000
name: life cycle stage
def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [UBERON:0000105]
synonym: "developmental stage" EXACT []
synonym: "stage" NARROW []
xref: UBERON:0000105

[Term]
id: MmusDv:0000001
name: life cycle
namespace: mouse_developmental_stage
def: "Temporal interval that defines mouse life from prenatal stage until late adult stage." [Bgee:curator "Bgee"]
xref: UBERON:0000104
is_a: MmusDv:0000000 ! life cycle stage
property_value: start_dpc "0.45" xsd:float

[Term]
id: MmusDv:0000042
name: prenatal stage
namespace: mouse_developmental_stage
def: "Mouse life cycle that starts with fertilization and ends with birth." [UBERON:0000068 "adapted from"]
xref: UBERON:0000068
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000001 ! life cycle
property_value: start_dpf "0.0" xsd:float
property_value: start_dpc "0.45" xsd:float
property_value: end_dpc "19.0" xsd:float
property_value: end_ypb "0.0" xsd:float

[Term]
id: MmusDv:0000002
name: embryonic stage
namespace: mouse_developmental_stage
def: "Prenatal stage that starts with fertilization and ends with a fully formed embryo, before undergoing last development during the fetal stage." [Bgee:curator "Bgee"]
comment: By embryo we mean in the sense of up to the 2nd week postfertilization (beginning of Theiler stage 23), we treat fetus as a separate stage.
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000042 ! prenatal stage
property_value: start_dpf "0.0" xsd:float
property_value: start_dpc "0.45" xsd:float

[Term]
id: MmusDv:0000003
name: Theiler stage 01
namespace: mouse_developmental_stage
def: "Embryonic stage defined by a one-cell embryo (fertilised egg) with zona pellucida present." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_1 "adapted from"]
comment: "Starts the mouse development sequence, range from embryonic age 0-0.9 dpc (day post coitum). Assumes that fertilization takes place around midnight during a 7pm to 5am dark cycle. Noon of the day on which the vaginal plug is found the embryos are aged 0.5 d.p.c (days post coitum)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy "adapted from"]
synonym: "zygote stage" RELATED []
xref: UBERON:0000106
xref: XUO:0000045
synonym: "Theiler stage 1" EXACT []
synonym: "TS01 (E0-2.5)" RELATED [EMAPA:TS01]
synonym: "E0-2.5" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000002 ! embryonic stage
property_value: start_dpc "0.45" xsd:float
xref: EMAPA:TS01 ! TS01 (E0-2.5)

[Term]
id: MmusDv:0000004
name: cleavage stage
namespace: mouse_developmental_stage
def: "Embryonic stage consisting of division of cells in the early embryo." [UBERON:0000107 "adapted from"]
comment: The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula.
xref: UBERON:0000107
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000002 ! embryonic stage
relationship: immediately_preceded_by MmusDv:0000003 ! Theiler stage 01

[Term]
id: MmusDv:0000005
name: Theiler stage 02
namespace: mouse_developmental_stage
def: "Embryonic cleavage stage defined by a dividing 2-4 cells egg." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_2 "adapted from"]
comment: Embryonic age 1 dpc (day post coitum).
xref: XUO:0000046
synonym: "Theiler stage 2" EXACT []
synonym: "TS02 (E1-2.5)" RELATED [EMAPA:TS02]
synonym: "Theiler stage 2" EXACT []
synonym: "TS02" EXACT []
synonym: "E1-2.5" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000004 ! cleavage stage
relationship: immediately_preceded_by MmusDv:0000003 ! Theiler stage 01
property_value: start_dpc "1.0" xsd:float
xref: EMAPA:TS02 ! TS02 (E1-2.5)

[Term]
id: MmusDv:0000006
name: Theiler stage 03
namespace: mouse_developmental_stage
def: "Embryonic cleavage stage defined by a dividing 4-16 cells egg, early to fully compacted morula." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_3 "adapted from"]
comment: Embryonic age 2 dpc (day post coitum).
xref: XUO:0000047
synonym: "Theiler stage 3" EXACT []
synonym: "TS03 (E1-3.5)" RELATED [EMAPA:TS03]
synonym: "Theiler stage 3" EXACT []
synonym: "TS03" EXACT []
synonym: "E1-3.5" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000004 ! cleavage stage
relationship: immediately_preceded_by MmusDv:0000005 ! Theiler stage 02
property_value: start_dpc "2.0" xsd:float
xref: EMAPA:TS03 ! TS03 (E1-3.5)

[Term]
id: MmusDv:0000007
name: blastula stage
namespace: mouse_developmental_stage
def: "Embryonic stage that is an early stage of embryonic development in animals and is produced by cleavage of a fertilized ovum, with formation of a central fluid-filled cavity called the blastocoel." [UBERON:0000108 "adapted from"]
comment: The blastula follows the morula and precedes the gastrula in the developmental sequence.
xref: UBERON:0000108
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000002 ! embryonic stage
relationship: preceded_by MmusDv:0000004 ! cleavage stage

[Term]
id: MmusDv:0000008
name: Theiler stage 04
namespace: mouse_developmental_stage
def: "Embryonic blastula stage defined by a dividing 16-40 cells egg, with early evidence of the blastocoelic cavity." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_4 "adapted from"]
comment: Embryonic age 3 dpc (day post coitum).
xref: XUO:0000048
synonym: "Theiler stage 4" EXACT []
synonym: "TS04 (E2-4)" RELATED [EMAPA:TS04]
synonym: "Theiler stage 4" EXACT []
synonym: "TS04" EXACT []
synonym: "E2-4" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000007 ! blastula stage
relationship: immediately_preceded_by MmusDv:0000006 ! Theiler stage 03
property_value: start_dpc "3.0" xsd:float
xref: EMAPA:TS04 ! TS04 (E2-4)

[Term]
id: MmusDv:0000009
name: Theiler stage 05
namespace: mouse_developmental_stage
def: "Embryonic blastula stage defined by a zona free blastocyst (zona pellucida absent)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_5 "adapted from"]
comment: Embryonic age 4 dpc (day post coitum).
xref: XUO:0000049
synonym: "Theiler stage 5" EXACT []
synonym: "TS05 (E3-5.5)" RELATED [EMAPA:TS05]
synonym: "Theiler stage 5" EXACT []
synonym: "TS05" EXACT []
synonym: "E3-5.5" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000007 ! blastula stage
relationship: immediately_preceded_by MmusDv:0000008 ! Theiler stage 04
property_value: start_dpc "4.0" xsd:float
property_value: has_stage_marker GO:0001835 ! blastocyst hatching
xref: EMAPA:TS05 ! TS05 (E3-5.5)

[Term]
id: MmusDv:0000010
name: Theiler stage 06
namespace: mouse_developmental_stage
def: "Embryonic blastula stage during which the blastocyst attaches, with first evidence of embryonic endoderm cells covering the blastocoelic surface of the inner cell mass." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_6 "adapted from"]
comment: Embryonic age 4.5 dpc (day post coitum). Refers to human CarnegieStage04.
xref: XUO:0000050
synonym: "Theiler stage 6" EXACT []
synonym: "TS06 (E4-5.5)" RELATED [EMAPA:TS06]
synonym: "Theiler stage 6" EXACT []
synonym: "TS06" EXACT []
synonym: "E4-5.5" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000007 ! blastula stage
relationship: immediately_preceded_by MmusDv:0000009 ! Theiler stage 05
property_value: start_dpc "4.5" xsd:float
xref: EMAPA:TS06 ! TS06 (E4-5.5)

[Term]
id: MmusDv:0000011
name: Theiler stage 07
namespace: mouse_developmental_stage
def: "Embryonic blastula stage defined by implantation and formation of the egg cylinder resulting from the rapid increase in the number of inner cell mass cells." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_7 "adapted from"]
comment: Embryonic age 5 dpc (day post coitum). Refers to human CarnegieStage05.
xref: XUO:0000051
synonym: "Theiler stage 7" EXACT []
synonym: "TS07 (E4.5-6)" RELATED [EMAPA:TS07]
synonym: "Theiler stage 7" EXACT []
synonym: "TS07" EXACT []
synonym: "E4.5-6" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000007 ! blastula stage
relationship: immediately_preceded_by MmusDv:0000010 ! Theiler stage 06
property_value: start_dpc "5.0" xsd:float
property_value: has_stage_marker GO:0007566 ! embryo implantation
xref: EMAPA:TS07 ! TS07 (E4.5-6)

[Term]
id: MmusDv:0000012
name: Theiler stage 08
namespace: mouse_developmental_stage
def: "Embryonic blastula stage during which the egg cylinder differentiates into embryonic and extra-embryonic regions, and the pro-amniotic cavity appears." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_8 "adapted from"]
comment: Embryonic age 6 dpc (day post coitum). Refers to human CarnegieStage05.
xref: XUO:0000052
synonym: "Theiler stage 8" EXACT []
synonym: "TS08 (E5-6.5)" RELATED [EMAPA:TS08]
synonym: "Theiler stage 8" EXACT []
synonym: "TS08" EXACT []
synonym: "E5-6.5" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000007 ! blastula stage
relationship: immediately_preceded_by MmusDv:0000011 ! Theiler stage 07
property_value: start_dpc "6.0" xsd:float
xref: EMAPA:TS08 ! TS08 (E5-6.5)

[Term]
id: MmusDv:0000013
name: gastrula stage
namespace: mouse_developmental_stage
def: "Embryonic stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage." [UBERON:0000109 "adapted from"]
xref: UBERON:0000109
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000002 ! embryonic stage
relationship: immediately_preceded_by MmusDv:0000007 ! blastula stage

[Term]
id: MmusDv:0000014
name: Theiler stage 09
namespace: mouse_developmental_stage
def: "Embryonic gastrula stage during which gastrulation starts with first evidence of mesoderm and visible embryonic axis." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_9 "adapted from"]
comment: Embryonic age 6.5 dpc (day post coitum).
xref: XUO:0000053
synonym: "Theiler stage 9" EXACT []
synonym: "TS09 (E6.25-7.25)" RELATED [EMAPA:TS09]
synonym: "Theiler stage 9" EXACT []
synonym: "TS09" EXACT []
synonym: "E6.25-7.25" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000013 ! gastrula stage
relationship: immediately_preceded_by MmusDv:0000012 ! Theiler stage 08
property_value: start_dpc "6.5" xsd:float
property_value: has_stage_marker UBERON:0000926 ! mesoderm
xref: EMAPA:TS09 ! TS09 (E6.25-7.25)

[Term]
id: MmusDv:0000103
name: Theiler stage 09a
namespace: mouse_developmental_stage
def: "Theiler developmental stage 9 defined by advanced endometrial reaction and during which the egg-cylinder stage advances with the first evidence of an embryonic axis." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_9a "adapted from"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000014 ! Theiler stage 09
synonym: "Theiler stage 9" EXACT []
synonym: "TS09a" EXACT []

[Term]
id: MmusDv:0000104
name: Theiler stage 09b
namespace: mouse_developmental_stage
def: "Theiler developmental stage 9 defined by advanced endometrial reaction and during which the first mesodermal cells are produced by gastrulation late in this stage." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_9b "adapted from"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000014 ! Theiler stage 09
relationship: immediately_preceded_by MmusDv:0000103 ! Theiler stage 09a
synonym: "Theiler stage 9" EXACT []
synonym: "TS09b" EXACT []

[Term]
id: MmusDv:0000015
name: Theiler stage 10
namespace: mouse_developmental_stage
def: "Embryonic gastrula stage during which the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold; the exocoelom appears; the allantoic bud first appears, gastrulation continues and the node becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10 "adapted from"]
comment: Embryonic age 7 dpc (day post coitum), (range 6.5-7.5 dpc). Refers to human CarnegieStage08.
xref: XUO:0000054
synonym: "TS10 (E6.5-7.75)" RELATED [EMAPA:TS10]
synonym: "TS10" EXACT []
synonym: "E6.5-7.75" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000013 ! gastrula stage
relationship: immediately_preceded_by MmusDv:0000014 ! Theiler stage 09
property_value: start_dpc "7.0" xsd:float
property_value: has_stage_marker UBERON:0005971 ! amniotic fold
property_value: has_stage_marker UBERON:0003888 ! extraembryonic coelom
property_value: has_stage_marker UBERON:0004340 ! allantois
xref: EMAPA:TS10 ! TS10 (E6.5-7.75)

[Term]
id: MmusDv:0000105
name: Theiler stage 10a
namespace: mouse_developmental_stage
def: "Theiler developmental stage 10 during which the tissue at the posterior end of the primitive streak bulges into the pro-amniotic cavity and forms the amniotic fold." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Stage_10a "adapted from"]
comment: Refers to MS (mid-streak) stage in Downs and Davies staging of gastrulating mouse embryos (PMID: 8269852, 1993).
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000015 ! Theiler stage 10
synonym: "TS10a" EXACT []

[Term]
id: MmusDv:0000106
name: Theiler stage 10b
namespace: mouse_developmental_stage
def: "Theiler developmental stage 10 during which small cavities coalesce to form a single cavity in the mesoderm of the posterior amniotic fold, the exocoelom." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10b "adapted from"]
comment: Refers to MS-LS (mid-streak to late streak) stage in Downs and Davies staging of gastrulating mouse embryos, 1993 (see http://www.ncbi.nlm.nih.gov/pubmed/8269852).
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000015 ! Theiler stage 10
relationship: immediately_preceded_by MmusDv:0000105 ! Theiler stage 10a
synonym: "TS10b" EXACT []

[Term]
id: MmusDv:0000107
name: Theiler stage 10c
namespace: mouse_developmental_stage
def: "Theiler developmental stage 10 during which the allantoic bud first appears, gastrulation continues and the node becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_10c "adapted from"]
comment: Refers to MS-LS (mid-streak to late streak) stage in Downs and Davies staging of gastrulating mouse embryos, 1993 (see http://www.ncbi.nlm.nih.gov/pubmed/8269852).
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000015 ! Theiler stage 10
relationship: immediately_preceded_by MmusDv:0000106 ! Theiler stage 10b
synonym: "TS10c" EXACT []

[Term]
id: MmusDv:0000016
name: neurula stage
namespace: mouse_developmental_stage
def: "Embryonic stage defined by formation of a tube from the flat layer of ectodermal cells known as the neural plate." [UBERON:0000110 "adapted from"]
comment: This term was obsoleted as it was the only child associated to MmusDv:0000017., This stage starts the emergence of the central nervous system at embryonic age 7.5 dpc (day post coitum).
synonym: "TheilerStage11" RELATED []
is_obsolete: true
consider: MmusDv:0000017

[Term]
id: MmusDv:0000017
name: Theiler stage 11
namespace: mouse_developmental_stage
def: "Embryonic stage called presomite stage and defined by the formation of the neural plate." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 "adapted from"]
comment: This stage starts the emergence of the central nervous system at embryonic age 7.5 dpc (day post coitum).
synonym: "neurula stage" RELATED []
xref: XUO:0000055
synonym: "TS11 (E7.25-8)" RELATED [EMAPA:TS11]
synonym: "TS11" EXACT []
synonym: "E7.25-8" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000002 ! embryonic stage
relationship: immediately_preceded_by MmusDv:0000015 ! Theiler stage 10
property_value: start_dpc "7.5" xsd:float
property_value: has_stage_marker UBERON:0003075 ! neural plate
xref: EMAPA:TS11 ! TS11 (E7.25-8)
xref: UBERON:0000110

[Term]
id: MmusDv:0000111
name: Theiler stage 11a
namespace: mouse_developmental_stage
def: "Embryonic neurula stage during which the neural plate formation occurs and the amniotic cavity is sealed off into three distinct cavities - the amniotic cavity, the exocoelom and the ectoplacental cleft." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 "adapted from"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000017 ! Theiler stage 11
synonym: "TS11a" EXACT []

[Term]
id: MmusDv:0000093
name: Theiler stage 11b
namespace: mouse_developmental_stage
def: "Embryonic neurula stage during which the neural plate formation occurs and the allantoic bud elongates ." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 "adapted from"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000017 ! Theiler stage 11
relationship: immediately_preceded_by MmusDv:0000111 ! Theiler stage 11a
synonym: "TS11b" EXACT []

[Term]
id: MmusDv:0000094
name: Theiler stage 11c
namespace: mouse_developmental_stage
def: "Embryonic neurula stage during which the neural plate formation occurs and the head folds are formed while the neural groove becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 "adapted from"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000017 ! Theiler stage 11
relationship: immediately_preceded_by MmusDv:0000093 ! Theiler stage 11b
synonym: "TS11c" EXACT []

[Term]
id: MmusDv:0000095
name: Theiler stage 11d
namespace: mouse_developmental_stage
def: "Embryonic neurula stage during which the neural plate formation occurs and the head folds continue to enlarge while the foregut pocket begins to form." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_11 "adapted from"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000017 ! Theiler stage 11
relationship: immediately_preceded_by MmusDv:0000094 ! Theiler stage 11c
synonym: "TS11d" EXACT []

[Term]
id: MmusDv:0000018
name: organogenesis stage
namespace: mouse_developmental_stage
def: "Embryonic stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism." [UBERON:0000111 "adapted from"]
xref: UBERON:0000111
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000002 ! embryonic stage
relationship: immediately_preceded_by MmusDv:0000095 ! Theiler stage 11d

[Term]
id: MmusDv:0000019
name: Theiler stage 12
namespace: mouse_developmental_stage
def: "Organogenesis stage during which first somites become visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12 "adapted from"]
comment: Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09.
xref: XUO:0000056
synonym: "TS12 (E7.5-8.75)" RELATED [EMAPA:TS12]
synonym: "TS12" EXACT []
synonym: "E7.5-8.75" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000017 ! Theiler stage 11
property_value: start_dpc "8.0" xsd:float
property_value: has_stage_marker EMAPA:16173 ! somite 01
xref: EMAPA:TS12 ! TS12 (E7.5-8.75)

[Term]
id: MmusDv:0000108
name: Theiler stage 12a
namespace: mouse_developmental_stage
def: "Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 1-4 and during which the allantois extends further into the exocoelom. Maxillary components of the 1st branchial arch become prominent. The preotic sulcus is visible in the 2-3 somite embryo. The cardiogenic plate begins to form and the foregut pocket is clearly visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12a "adapted from"]
comment: Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09.
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000019 ! Theiler stage 12
synonym: "TS12a" EXACT []

[Term]
id: MmusDv:0000109
name: Theiler stage 12b
namespace: mouse_developmental_stage
def: "Theiler developmental stage 12 defined by unturned embryo with first appearance of somite pairs 5-7 and during which neural closure occurs in the region of the 4th and 5th somites, extending in both directions from this site. Headfolds are particularly prominent. Optic placodes are first evident and become indented to form the optic pits. The heart rudiment develops rapidly. The allantois contacts the chorion at the end of this stage." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_12b "adapted from"]
comment: Embryonic age 8 dpc (day post coitum). Refers to human CarnegieStage09.
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000019 ! Theiler stage 12
relationship: immediately_preceded_by MmusDv:0000108 ! Theiler stage 12a
synonym: "TS12b" EXACT []

[Term]
id: MmusDv:0000020
name: Theiler stage 13
namespace: mouse_developmental_stage
def: "Organogenesis stage defined by the turning of the embryo; initiated in embryos with 6-8 pairs of somites and usually completed in embryos with 14-16 pairs of somites." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_13 "adapted from"]
comment: Embryonic age 8.5 dpc (day post coitum). Refers to human CarnegieStage10.
xref: XUO:0000057
synonym: "TS13 (E8-9.25)" RELATED [EMAPA:TS13]
synonym: "TS13" EXACT []
synonym: "E8-9.25" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000019 ! Theiler stage 12
property_value: start_dpc "8.5" xsd:float
property_value: has_stage_marker EMAPA:16441 ! somite 14
property_value: has_stage_marker EMAPA:16445 ! somite 15
property_value: has_stage_marker EMAPA:16449 ! somite 16
xref: EMAPA:TS13 ! TS13 (E8-9.25)

[Term]
id: MmusDv:0000021
name: Theiler stage 14
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the rostral extremity of the neural tube closes in embryos with usually about 15-18 somite pairs. Late in the stage the 3rd branchial arch becomes visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_14 "adapted from"]
comment: Embryonic age 9 dpc (day post coitum). Refers to human CarnegieStage11.
xref: XUO:0000058
synonym: "TS14 (E8.5-9.75)" RELATED [EMAPA:TS14]
synonym: "TS14" EXACT []
synonym: "E8.5-9.75" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000020 ! Theiler stage 13
property_value: start_dpc "9.0" xsd:float
property_value: has_stage_marker EMAPA:16445 ! somite 15
property_value: has_stage_marker EMAPA:16449 ! somite 16
property_value: has_stage_marker EMAPA:16453 ! somite 17
property_value: has_stage_marker EMAPA:16457 ! somite 18
xref: EMAPA:TS14 ! TS14 (E8.5-9.75)

[Term]
id: MmusDv:0000022
name: Theiler stage 15
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the posterior neuropore forms and the condensation of the forelimb bud becomes apparent near the 8th-12th somite pairs." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_15 "adapted from"]
comment: Embryonic age 9.5 dpc (day post coitum). Refers to human CarnegieStage12.
xref: XUO:0000059
synonym: "TS15 (E9-10.25)" RELATED [EMAPA:TS15]
synonym: "TS15" EXACT []
synonym: "E9-10.25" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000021 ! Theiler stage 14
property_value: start_dpc "9.5" xsd:float
property_value: has_stage_marker UBERON:0005417 ! forelimb bud
xref: EMAPA:TS15 ! TS15 (E9-10.25)

[Term]
id: MmusDv:0000023
name: Theiler stage 16
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the posterior neuropore closes and the hind limb bud becomes visible at the level of the 23rd-28th somites." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_16 "adapted from"]
comment: Embryonic age 10 dpc (day post coitum). Refers to human CarnegieStages 13 to 15.
xref: XUO:0000060
synonym: "TS16 (E9.5-10.75)" RELATED [EMAPA:TS16]
synonym: "TS16" EXACT []
synonym: "E9.5-10.75" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000022 ! Theiler stage 15
property_value: start_dpc "10.0" xsd:float
property_value: has_stage_marker UBERON:0005418 ! hindlimb bud
xref: EMAPA:TS16 ! TS16 (E9.5-10.75)

[Term]
id: MmusDv:0000024
name: Theiler stage 17
namespace: mouse_developmental_stage
def: "Organogenesis stage defined by the deepening of the lens pit and the first appearance of the physiological umbilical hernia." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_17 "adapted from"]
comment: Embryonic age 10.5 dpc (day post coitum). Refers to human CarnegieStages 13 to 15.
xref: XUO:0000061
synonym: "TS17 (E10-11.25)" RELATED [EMAPA:TS17]
synonym: "TS17" EXACT []
synonym: "E10-11.25" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000023 ! Theiler stage 16
property_value: start_dpc "10.5" xsd:float
property_value: has_stage_marker UBERON:0006259 ! lens pit
property_value: has_stage_marker EMAPA:18411 ! physiological umbilical hernia
xref: EMAPA:TS17 ! TS17 (E10-11.25)

[Term]
id: MmusDv:0000025
name: Theiler stage 18
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the lens vesicle gradually closes and the nasal pits start to form. The rapid growth of the brain is striking." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_18 "adapted from"]
comment: Embryonic age 11 dpc (day post coitum). Refers to human CarnegieStages 13 to 15.
xref: XUO:0000062
synonym: "TS18 (E10.5-11.25)" RELATED [EMAPA:TS18]
synonym: "TS18" EXACT []
synonym: "E10.5-11.25" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000024 ! Theiler stage 17
property_value: start_dpc "11.0" xsd:float
property_value: has_stage_marker UBERON:0005870 ! olfactory pit
xref: EMAPA:TS18 ! TS18 (E10.5-11.25)

[Term]
id: MmusDv:0000026
name: Theiler stage 19
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the lens vesicle becomes completely closed and detached from the ectoderm, and peripheral margins of the eye become well defined." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_19 "adapted from"]
comment: Embryonic age 11.5 dpc (day post coitum). Refers to human CarnegieStage16.
xref: XUO:0000063
synonym: "TS19 (E11-12.25)" RELATED [EMAPA:TS19]
synonym: "TS19" EXACT []
synonym: "E11-12.25" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000025 ! Theiler stage 18
property_value: start_dpc "11.5" xsd:float
xref: EMAPA:TS19 ! TS19 (E11-12.25)

[Term]
id: MmusDv:0000027
name: Theiler stage 20
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the handplate develops angles corresponding to the future digits, and tongue and brain vesicles are clearly visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_20 "adapted from"]
comment: Embryonic age 12 dpc (day post coitum). Refers to human CarnegieStage17.
xref: XUO:0000064
synonym: "TS20 (E11.5-13)" RELATED [EMAPA:TS20]
synonym: "TS20" EXACT []
synonym: "E11.5-13" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000026 ! Theiler stage 19
property_value: start_dpc "12.0" xsd:float
xref: EMAPA:TS20 ! TS20 (E11.5-13)

[Term]
id: MmusDv:0000028
name: Theiler stage 21
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the digit widths and locations can be discerned, and the pinna rapidly develops and forms a crest at right angles to the head." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_21 "adapted from"]
comment: Embryonic age 13 dpc (day post coitum). Refers to human CarnegieStages 18 and 19.
xref: XUO:0000065
synonym: "TS21 (E12.5-14)" RELATED [EMAPA:TS21]
synonym: "TS21" EXACT []
synonym: "E12.5-14" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
property_value: start_dpc "13.0" xsd:float
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000027 ! Theiler stage 20
xref: EMAPA:TS21 ! TS21 (E12.5-14)

[Term]
id: MmusDv:0000029
name: Theiler stage 22
namespace: mouse_developmental_stage
def: "Organogenesis stage during which the fingers are clearly visible and the long bones of the limbs are present." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_22 "adapted from"]
comment: Embryonic age 14 dpc (day post coitum). Refers to human CarnegieStages 20 to 23.
xref: XUO:0000066
synonym: "TS22 (E13.5-15)" RELATED [EMAPA:TS22]
synonym: "TS22" EXACT []
synonym: "E13.5-15" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000018 ! organogenesis stage
relationship: immediately_preceded_by MmusDv:0000028 ! Theiler stage 21
property_value: start_dpc "14.0" xsd:float
property_value: has_stage_marker UBERON:0003606 ! limb long bone
xref: EMAPA:TS22 ! TS22 (E13.5-15)

[Term]
id: MmusDv:0000030
name: post-embryonic developmental stage
namespace: mouse_developmental_stage
def: "life cycle that follows the embryonic development stage and during which further organogenesis and histogenesis occur." [Bgee:curator "Bgee"]
is_obsolete: true
comment: This term was obsoleted to follow human developmental ontology structure.

[Term]
id: MmusDv:0000031
name: fetal stage
namespace: mouse_developmental_stage
def: "Prenatal stage that starts with the fully formed embryo and ends at birth." [Bgee:curator "Bgee"]
comment: This stage describes the four Theiler stages that are commonly reported as equivalent to the human fetal period in the literature. They are anyway defined by embryonic days.
xref: UBERON:0007220
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000042 ! prenatal stage
relationship: immediately_preceded_by MmusDv:0000002 ! embryonic stage

[Term]
id: MmusDv:0000032
name: Theiler stage 23
namespace: mouse_developmental_stage
def: "Fetal stage during which the toes separate and hair follicles are present in the cephalic region but not at the periphery of the vibrissae." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_23 "adapted from"]
comment: Embryonic age 15 dpc (day post coitum). Refers to the human fetal period.
xref: XUO:0000067
synonym: "TS23 (E15)" RELATED [EMAPA:TS23]
synonym: "TS23" EXACT []
synonym: "E15" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000031 ! fetal stage
relationship: immediately_preceded_by MmusDv:0000029 ! Theiler stage 22
property_value: start_dpc "15.0" xsd:float
xref: EMAPA:TS23 ! TS23 (E15)

[Term]
id: MmusDv:0000033
name: Theiler stage 24
namespace: mouse_developmental_stage
def: "Fetal stage during which the umbilical hernia disappears and there is a corresponding increase in the size of the peritoneal sac." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_24 "adapted from"]
comment: Embryonic age 16 dpc (day post coitum). Refers to the human fetal period.
xref: XUO:0000068
synonym: "TS24 (E16)" RELATED [EMAPA:TS24]
synonym: "TS24" EXACT []
synonym: "E16" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000031 ! fetal stage
relationship: immediately_preceded_by MmusDv:0000032 ! Theiler stage 23
property_value: start_dpc "16.0" xsd:float
xref: EMAPA:TS24 ! TS24 (E16)

[Term]
id: MmusDv:0000034
name: Theiler stage 25
namespace: mouse_developmental_stage
def: "Fetal stage during which the thickened skin forms wrinkles and the subcutaneous veins are less visible." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_25 "adapted from"]
comment: Embryonic age 17 dpc (day post coitum). Refers to the human fetal period. Refers to rat Standard Witschi Stage 34 (see http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_25).
xref: XUO:0000069
synonym: "TS25 (E17)" RELATED [EMAPA:TS25]
synonym: "TS25" EXACT []
synonym: "E17" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000031 ! fetal stage
relationship: immediately_preceded_by MmusDv:0000033 ! Theiler stage 24
property_value: start_dpc "17.0" xsd:float
xref: EMAPA:TS25 ! TS25 (E17)

[Term]
id: MmusDv:0000035
name: Theiler stage 26
namespace: mouse_developmental_stage
def: "Fetal stage defined by long whiskers and during which the eyes are barely visible through the closed eyelids." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_26 "adapted from"]
comment: TS26 is used for the period from embryonic day 18 up to birth itself. [https://github.com/tfhayamizu]. Refers to rat Standard Witschi Stage 35 (see http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Theiler_Stage_26).
xref: XUO:0000070
synonym: "TS26 (E18)" RELATED [EMAPA:TS26]
synonym: "TS26" EXACT []
synonym: "E18" EXACT []
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000031 ! fetal stage
relationship: immediately_preceded_by MmusDv:0000034 ! Theiler stage 25
property_value: start_dpc "18.0" xsd:float
property_value: end_wpb "0.0" xsd:float
xref: EMAPA:TS26 ! TS26 (E18)

[Term]
id: MmusDv:0000092
name: postnatal stage
namespace: mouse_developmental_stage
def: "Mouse developmental stage that covers the period from birth until late adulthood." [Bgee:curator "Bgee"]
xref: UBERON:0000066
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000001 ! life cycle
relationship: immediately_preceded_by MmusDv:0000042 ! prenatal stage
property_value: start_dpc "19.0" xsd:float
property_value: start_wpb "0.0" xsd:float

[Term]
id: MmusDv:0000043
name: immature stage
namespace: mouse_developmental_stage
def: "Mouse developmental stage that covers the period from birth until 5 weeks old." [Bgee:curator "Bgee"]
comment: It is commonly accepted that mouse reaches sexual maturity by six weeks of age (see http://www.ahc.umn.edu/rar/breeding.html).
xref: UBERON:0000112
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000092 ! postnatal stage
property_value: start_wpb "0.0" xsd:float
property_value: end_wpb "6.0" xsd:float
xref: EMAPA:TS28 ! TS28 (P0-Adult)

[Term]
id: MmusDv:0000138
name: nursing stage
namespace: mouse_developmental_stage
def: "Mouse developmental stage that covers the period from birth until 22 days old, at which point individuals wean." [Bgee:curator "Bgee"]
comment: Age of weaning is 22 days (see https://genomics.senescence.info/species/entry.php?species=Mus_musculus).
xref: UBERON:0018685
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000043 ! immature stage
property_value: start_dpb "0.0" xsd:float
property_value: end_dpb "23.0" xsd:float

[Term]
id: MmusDv:0000096
name: early immature stage
namespace: mouse_developmental_stage
def: "Immature stage that covers the period from birth until end of the first week." [Bgee:curator "Bgee"]
comment: This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad]
property_value: start_dpc "19.0" xsd:float
property_value: start_wpb "0.0" xsd:float
property_value: end_wpb "1.0" xsd:float
is_obsolete: true
consider: MmusDv:0000036
consider: MmusDv:0000139

[Term]
id: MmusDv:0000036
name: Theiler stage 27
namespace: mouse_developmental_stage
def: "Stage that refers to the newborn mouse, aged E19-20, P0. Description of anatomical structures related to this stage corresponds to the first days of the mouse life. Used for postnatal days 0 through 3." [https://github.com/tfhayamizu "adapted from"]
comment: TS27 is used for annotation of postnatal days 0 through 3 (P0 to P3). This is a somewhat arbitrary cut-off but seems to best fit the data we have encountered. TS28 is then used from postnatal day 4 onward. [https://github.com/tfhayamizu]
xref: XUO:0000071
xref: UBERON:0007221
xref: EMAPA:TS27 ! TS27 (null)
synonym: "TS27" RELATED [EMAPA:TS27]
synonym: "newborn stage" EXACT [UBERON:cjm]
synonym: "P0" RELATED [UBERON:cjm]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000138 ! nursing stage
relationship: immediately_preceded_by MmusDv:0000035 ! Theiler stage 26
property_value: start_dpc "19.0" xsd:float
property_value: start_wpb "0.0" xsd:float
property_value: end_wpb "0.6" xsd:float
property_value: start_dpb "0.0" xsd:float
property_value: end_dpb "4.0" xsd:float

[Term]
id: MmusDv:0000037
name: Theiler stage 28
namespace: mouse_developmental_stage
def: "Development stage that defines the postnatal period, all the way through adulthood." [https://github.com/tfhayamizu "adapted from"]
comment: TS27 is used for annotation of postnatal days 0 through 3 (P0 to P3). This is a somewhat arbitrary cut-off but seems to best fit the data we have encountered. TS28 is then used from postnatal day 4 onward. [https://github.com/tfhayamizu]
property_value: start_wpb "0.6" xsd:float
is_obsolete: true

[Term]
id: MmusDv:0000112
name: premature stage
namespace: mouse_developmental_stage
def: "Mouse developmental stage that covers the period from P4 starting at TS28 until 5 weeks old." [Bgee:curator "Bgee"]
comment: It is commonly accepted that mouse reaches sexual maturity by six weeks of age (see http://www.ahc.umn.edu/rar/breeding.html). We start this stage at P4 because TS27 'newborn' stage is not defined as a postnatal stage.
synonym: "infant stage" RELATED []
property_value: start_wpb "0.6" xsd:float
property_value: end_wpb "6.0" xsd:float
is_obsolete: true
consider: MmusDv:0000139
consider: MmusDv:0000140
consider: MmusDv:0000141
consider: MmusDv:0000142
consider: MmusDv:0000143
consider: MmusDv:0000144
consider: MmusDv:0000145
consider: MmusDv:0000146
consider: MmusDv:0000147
consider: MmusDv:0000148
consider: MmusDv:0000149
consider: MmusDv:0000150

[Term]
id: MmusDv:0000038
name: infant stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 1 week and under 6 weeks old." [Bgee:curator "Bgee"]
comment: This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad]
synonym: "1-5 weeks" EXACT []
property_value: start_wpb "1.0" xsd:float
property_value: end_wpb "6.0" xsd:float
is_obsolete: true
consider: MmusDv:0000140
consider: MmusDv:0000141
consider: MmusDv:0000142
consider: MmusDv:0000143
consider: MmusDv:0000144
consider: MmusDv:0000145
consider: MmusDv:0000146
consider: MmusDv:0000147
consider: MmusDv:0000148
consider: MmusDv:0000149
consider: MmusDv:0000150

[Term]
id: MmusDv:0000039
name: adolescent stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 4 weeks and under 7 weeks old." [Bgee:curator "Bgee"]
comment: This term was obsoleted as it is not fully accepted as a defined developmental stage in the literature. This stage describes the age at which mice are usually used as adolescent mouse models in the literature. 
synonym: "4-6 weeks" EXACT []
is_obsolete: true

[Term]
id: MmusDv:0000040
name: adult stage
namespace: mouse_developmental_stage
def: "Mouse developmental stage that refers to a mouse which is over 5 weeks old." [Bgee:curator "Bgee"]
comment: This term was obsoleted to include the mature stage into the ontology. Both terms have the same children, but contains of children (children of children) differ. The organisation of the postnatal development time in mouse is debatable, literature usually refers to mature or immature mice, with milestone around 6-8 weeks post-natal.
synonym: "mature" EXACT []
is_obsolete: true
replaced_by: MmusDv:0000110

[Term]
id: MmusDv:0000041
name: unknown
namespace: mouse_developmental_stage
is_obsolete: true

[Term]
id: MmusDv:0000044
name: 1-7 days
namespace: mouse_developmental_stage
def: "Early immature stage that refers to the newborn mouse which is over 1 and under 8 days old." [Bgee:curator "Bgee"]
comment: This term was made obsolete due to discussion at https://github.com/obophenotype/developmental-stage-ontologies/issues/23. [ANiknejad]
property_value: start_wpb "0.143" xsd:float
property_value: end_wpb "1.143" xsd:float
is_obsolete: true
consider: MmusDv:0000036
consider: MmusDv:0000139

[Term]
id: MmusDv:0000113
name: 4-7 days
namespace: mouse_developmental_stage
def: "Premature stage that refers to the newborn mouse which is over 4 days and under 8 days old." [Bgee:curator "Bgee"]
comment: This stage starts at P4.
property_value: start_wpb "0.6" xsd:float
property_value: end_wpb "1.0" xsd:float
is_obsolete: true
consider: MmusDv:0000139

[Term]
id: MmusDv:0000177
name: infant stage
namespace: mouse_developmental_stage
def: "Nursing stage that follows the neonate stage in mouse and ends at weaning, at 22 days old." [Bgee:curator "Bgee"]
xref: UBERON:0034920
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000138 ! nursing stage
relationship: immediately_preceded_by MmusDv:0000036 ! Theiler stage 27
property_value: start_wpb "0.6" xsd:float
property_value: end_wpb "1.0" xsd:float
property_value: start_dpb "4.0" xsd:float
property_value: end_dpb "23.0" xsd:float

[Term]
id: MmusDv:0000139
name: 4-6 days
namespace: mouse_developmental_stage
def: "Immature stage that refers to the newborn mouse which is over 4 days and under 7 days old." [Bgee:curator "Bgee"]
comment: This stage starts at P4.
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000177 ! infant stage
property_value: start_wpb "0.6" xsd:float
property_value: end_wpb "1.0" xsd:float
property_value: start_dpb "4.0" xsd:float
property_value: end_dpb "7.0" xsd:float

[Term]
id: MmusDv:0000114
name: 4-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 4 and under 5 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000139 ! 4-6 days
relationship: immediately_preceded_by MmusDv:0000036 ! Theiler stage 27
property_value: start_dpb "4.0" xsd:float
property_value: end_dpb "5.0" xsd:float

[Term]
id: MmusDv:0000115
name: 5-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 5 and under 6 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000139 ! 4-6 days
relationship: immediately_preceded_by MmusDv:0000114 ! 4-day-old stage
property_value: start_dpb "5.0" xsd:float
property_value: end_dpb "6.0" xsd:float

[Term]
id: MmusDv:0000116
name: 6-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 6 and under 7 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000139 ! 4-6 days
relationship: immediately_preceded_by MmusDv:0000115 ! 5-day-old stage
property_value: start_dpb "6.0" xsd:float
property_value: end_dpb "7.0" xsd:float

[Term]
id: MmusDv:0000045
name: 1 week
namespace: mouse_developmental_stage
def: "Premature stage that refers to a mouse which is over 7 days and under 15 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "1.0" xsd:float
property_value: end_wpb "2.0" xsd:float
is_obsolete: true
consider: MmusDv:0000140

[Term]
id: MmusDv:0000140
name: 1-week-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 7 days and under 14 days old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000177 ! infant stage
relationship: immediately_preceded_by MmusDv:0000139 ! 4-6 days
property_value: start_wpb "1.0" xsd:float
property_value: end_wpb "2.0" xsd:float
property_value: start_dpb "7.0" xsd:float
property_value: end_dpb "14.0" xsd:float

[Term]
id: MmusDv:0000117
name: 7-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 7 and under 8 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000140 ! 1-week-old stage
relationship: immediately_preceded_by MmusDv:0000116 ! 6-day-old stage
property_value: start_dpb "7.0" xsd:float
property_value: end_dpb "8.0" xsd:float

[Term]
id: MmusDv:0000118
name: 8-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 8 and under 9 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000140 ! 1-week-old stage
relationship: immediately_preceded_by MmusDv:0000117 ! 7-day-old stage
property_value: start_dpb "8.0" xsd:float
property_value: end_dpb "9.0" xsd:float

[Term]
id: MmusDv:0000119
name: 9-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 9 and under 10 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000140 ! 1-week-old stage
relationship: immediately_preceded_by MmusDv:0000118 ! 8-day-old stage
property_value: start_dpb "9.0" xsd:float
property_value: end_dpb "10.0" xsd:float

[Term]
id: MmusDv:0000120
name: 10-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 10 and under 11 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000140 ! 1-week-old stage
relationship: immediately_preceded_by MmusDv:0000119 ! 9-day-old stage
property_value: start_dpb "10.0" xsd:float
property_value: end_dpb "11.0" xsd:float

[Term]
id: MmusDv:0000121
name: 11-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 11 and under 12 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000140 ! 1-week-old stage
relationship: immediately_preceded_by MmusDv:0000120 ! 10-day-old stage
property_value: start_dpb "11.0" xsd:float
property_value: end_dpb "12.0" xsd:float

[Term]
id: MmusDv:0000122
name: 12-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 12 and under 13 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000140 ! 1-week-old stage
relationship: immediately_preceded_by MmusDv:0000121 ! 11-day-old stage
property_value: start_dpb "12.0" xsd:float
property_value: end_dpb "13.0" xsd:float

[Term]
id: MmusDv:0000123
name: 13-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 13 and under 14 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000140 ! 1-week-old stage
relationship: immediately_preceded_by MmusDv:0000122 ! 12-day-old stage
property_value: start_dpb "13.0" xsd:float
property_value: end_dpb "14.0" xsd:float

[Term]
id: MmusDv:0000046
name: 2 weeks
namespace: mouse_developmental_stage
def: "Premature stage that refers to a mouse which is over 14 days and under 22 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "2.0" xsd:float
property_value: end_wpb "3.0" xsd:float
is_obsolete: true
consider: MmusDv:0000141

[Term]
id: MmusDv:0000141
name: 2-week-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 14 days and under 21 days old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000177 ! infant stage
relationship: immediately_preceded_by MmusDv:0000140 ! 1-week-old stage
property_value: start_wpb "2.0" xsd:float
property_value: end_wpb "3.0" xsd:float
property_value: start_dpb "14.0" xsd:float
property_value: end_dpb "21.0" xsd:float

[Term]
id: MmusDv:0000142
name: 21-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 21 and under 22 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000177 ! infant stage
relationship: immediately_preceded_by MmusDv:0000141 ! 2-week-old stage
property_value: start_dpb "21.0" xsd:float
property_value: end_dpb "22.0" xsd:float

[Term]
id: MmusDv:0000143
name: 22-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 22 and under 23 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000177 ! infant stage
relationship: immediately_preceded_by MmusDv:0000142 ! 21-day-old stage
property_value: start_dpb "22.0" xsd:float
property_value: end_dpb "23.0" xsd:float

[Term]
id: MmusDv:0000178
name: juvenile stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a weaned mouse which is over 23 days old, while still being an sexually immature mouse." [Bgee:curator "Bgee"]
subset: granular_stage
xref: UBERON:0034919
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000043 ! immature stage
relationship: immediately_preceded_by MmusDv:0000177 ! infant stage
property_value: start_dpb "23.0" xsd:float
property_value: end_dpb "24.0" xsd:float

[Term]
id: MmusDv:0000144
name: 23-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 23 and under 24 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000178 ! juvenile stage
relationship: immediately_preceded_by MmusDv:0000143 ! 22-day-old stage
property_value: start_dpb "23.0" xsd:float
property_value: end_dpb "24.0" xsd:float

[Term]
id: MmusDv:0000145
name: 24-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 24 and under 25 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000178 ! juvenile stage
relationship: immediately_preceded_by MmusDv:0000144 ! 23-day-old stage
property_value: start_dpb "24.0" xsd:float
property_value: end_dpb "25.0" xsd:float

[Term]
id: MmusDv:0000146
name: 25-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 25 and under 26 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000178 ! juvenile stage
relationship: immediately_preceded_by MmusDv:0000145 ! 24-day-old stage
property_value: start_dpb "21.0" xsd:float
property_value: end_dpb "22.0" xsd:float

[Term]
id: MmusDv:0000147
name: 26-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 26 and under 27 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000178 ! juvenile stage
relationship: immediately_preceded_by MmusDv:0000146 ! 25-day-old stage
property_value: start_dpb "26.0" xsd:float
property_value: end_dpb "27.0" xsd:float

[Term]
id: MmusDv:0000148
name: 27-day-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 27 and under 28 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000178 ! juvenile stage
relationship: immediately_preceded_by MmusDv:0000147 ! 26-day-old stage
property_value: start_dpb "27.0" xsd:float
property_value: end_dpb "28.0" xsd:float

[Term]
id: MmusDv:0000047
name: 3-week-old stage
namespace: mouse_developmental_stage
def: "Premature stage that refers to a mouse which is over 21 days and under 29 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "3.0" xsd:float
property_value: end_wpb "4.0" xsd:float
is_obsolete: true
consider: MmusDv:0000142
consider: MmusDv:0000143
consider: MmusDv:0000144
consider: MmusDv:0000145
consider: MmusDv:0000146
consider: MmusDv:0000147
consider: MmusDv:0000148

[Term]
id: MmusDv:0000048
name: 4 weeks
namespace: mouse_developmental_stage
def: "Premature stage that refers to a mouse which is over 28 days and under 36 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "4.0" xsd:float
property_value: end_wpb "5.0" xsd:float
is_obsolete: true
consider: MmusDv:0000149

[Term]
id: MmusDv:0000149
name: 4-week-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 28 days and under 35 days old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000178 ! juvenile stage
relationship: immediately_preceded_by MmusDv:0000148 ! 27-day-old stage
property_value: start_wpb "4.0" xsd:float
property_value: end_wpb "5.0" xsd:float
property_value: start_dpb "28.0" xsd:float
property_value: end_dpb "35.0" xsd:float

[Term]
id: MmusDv:0000049
name: 5 weeks
namespace: mouse_developmental_stage
def: "Premature stage that refers to a mouse which is over 35 days and under 43 days old." [Bgee:curator "Bgee"]
comment: This stage is usually the stage during which the sexual maturity occurs.
property_value: start_wpb "5.0" xsd:float
property_value: end_wpb "6.0" xsd:float
is_obsolete: true
consider: MmusDv:0000150

[Term]
id: MmusDv:0000150
name: 5-week-old stage
namespace: mouse_developmental_stage
def: "Immature stage that refers to a mouse which is over 35 days and under 42 days old." [Bgee:curator "Bgee"]
comment: This stage is usually the stage during which the sexual maturity occurs.
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000178 ! juvenile stage
relationship: immediately_preceded_by MmusDv:0000149 ! 4-week-old stage
property_value: start_wpb "5.0" xsd:float
property_value: end_wpb "6.0" xsd:float
property_value: start_dpb "35.0" xsd:float
property_value: end_dpb "42.0" xsd:float

[Term]
id: MmusDv:0000110
name: mature stage
namespace: mouse_developmental_stage
synonym: "mature" EXACT []
def: "Mouse developmental stage that refers to a sexually mature adult mouse which is over 6 weeks old." [Bgee:curator "Bgee"]
xref: UBERON:0000113
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000092 ! postnatal stage
relationship: immediately_preceded_by MmusDv:0000043 ! immature stage
property_value: start_wpb "6.0" xsd:float
property_value: start_mpb "1.5" xsd:float

[Term]
id: MmusDv:0000061
name: early adult stage
namespace: mouse_developmental_stage
def: "Mature stage that refers to a adult mouse which is over 6 weeks and under 7 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD "adapted from"]
comment: Mice under 7 months of age are commonly considered as young adult in the literature, without loss of functional capability like hearing (see http://www.ncbi.nlm.nih.gov/pubmed/18259074).
xref: UBERON:0018241
property_value: start_wpb "6.0" xsd:float
property_value: end_wpb "30.0" xsd:float
property_value: start_mpb "1.5" xsd:float
property_value: end_mpb "7.0" xsd:float
is_obsolete: true
consider: MmusDv:0000136

[Term]
id: MmusDv:0000136
name: prime adult stage
namespace: mouse_developmental_stage
def: "Mature stage that refers to a adult mouse which is over 6 weeks and under 18 months old." [Bgee:curator "Bgee"]
comment: Mice over 18 months old are considered as old (see https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old).
xref: UBERON:0018241
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000110 ! mouse mature stage
relationship: immediately_preceded_by MmusDv:0000150 ! 5-week-old stage
property_value: start_wpb "6.0" xsd:float
property_value: start_mpb "1.5" xsd:float
property_value: end_mpb "18.0" xsd:float

[Term]
id: MmusDv:0000153
name: young adult stage
namespace: mouse_developmental_stage
def: "Prime adult stage that refers to a sexually mature mouse under 10 months old." [Bgee:curator "Bgee"]
comment: This stage is adapted from https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old.
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000136 ! mouse prime adult stage
relationship: immediately_preceded_by MmusDv:0000150 ! 5-week-old stage
property_value: start_mpb "1.5" xsd:float
property_value: end_mpb "10.0" xsd:float

[Term]
id: MmusDv:0000050
name: 6 weeks
namespace: mouse_developmental_stage
def: "Early stage that refers to a mouse which is over 42 days and under 50 days old." [Bgee:curator "Bgee"]
comment: This stage is commonly considered in the literature as the milestone that distinguishes between sexually immmature and mature stages (see http://www.ahc.umn.edu/rar/breeding.html).
property_value: start_wpb "6.0" xsd:float
property_value: end_wpb "7.0" xsd:float
is_obsolete: true
consider: MmusDv:0000151

[Term]
id: MmusDv:0000151
name: 6-week-old stage
namespace: mouse_developmental_stage
def: "Prime adult stage that refers to a mouse which is over 42 days and under 49 days old." [Bgee:curator "Bgee"]
comment: This stage is commonly considered in the literature as the milestone that distinguishes between sexually immmature and mature stages (see http://www.ahc.umn.edu/rar/breeding.html).
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000153 ! young adult stage
relationship: immediately_preceded_by MmusDv:0000150 ! 5-week-old stage
property_value: start_wpb "6.0" xsd:float
property_value: end_wpb "7.0" xsd:float
property_value: start_dpb "42.0" xsd:float
property_value: end_dpb "49.0" xsd:float

[Term]
id: MmusDv:0000051
name: 7 weeks
namespace: mouse_developmental_stage
def: "Early adult stage that refers to a mouse which is over 49 days and under 57 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "7.0" xsd:float
property_value: end_wpb "8.0" xsd:float
is_obsolete: true
consider: MmusDv:0000152

[Term]
id: MmusDv:0000152
name: 7-week-old stage
namespace: mouse_developmental_stage
def: "Prime adult stage that refers to a mouse which is over 49 days and under 56 days old." [Bgee:curator "Bgee"]
comment: This stage is commonly considered in the literature as the milestone that distinguishes between sexually immmature and mature stages (see http://www.ahc.umn.edu/rar/breeding.html).
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000153 ! young adult stage
relationship: immediately_preceded_by MmusDv:0000151 ! 6-week-old stage
property_value: start_wpb "7.0" xsd:float
property_value: end_wpb "8.0" xsd:float
property_value: start_dpb "49.0" xsd:float
property_value: end_dpb "56.0" xsd:float

[Term]
id: MmusDv:0000062
name: 2-month-old stage
namespace: mouse_developmental_stage
def: "Early adult stage that refers to a mouse which is over 2 and under 3 months old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000153 ! young adult stage
relationship: immediately_preceded_by MmusDv:0000152 ! 7-week-old stage
property_value: start_wpb "8.0" xsd:float
property_value: end_wpb "12.0" xsd:float
property_value: start_mpb "2.0" xsd:float
property_value: end_mpb "3.0" xsd:float

[Term]
id: MmusDv:0000052
name: 8 weeks
namespace: mouse_developmental_stage
def: "2 month-old stage that refers to a mouse which is over 56 days and under 64 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "8.0" xsd:float
property_value: end_wpb "9.0" xsd:float
is_obsolete: true
consider: MmusDv:0000154

[Term]
id: MmusDv:0000154
name: 8-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 56 days and under 63 days old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000062 ! 2 month-old stage
property_value: start_wpb "8.0" xsd:float
property_value: end_wpb "9.0" xsd:float
property_value: start_dpb "56.0" xsd:float
property_value: end_dpb "63.0" xsd:float

[Term]
id: MmusDv:0000053
name: 9 weeks
namespace: mouse_developmental_stage
def: "2 month-old stage that refers to a mouse which is over 63 days and under 71 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "9.0" xsd:float
property_value: end_wpb "10.0" xsd:float
is_obsolete: true
consider: MmusDv:0000155

[Term]
id: MmusDv:0000155
name: 9-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 63 days and under 70 days old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000062 ! 2 month-old stage
relationship: immediately_preceded_by MmusDv:0000154 ! 8-week-old stage
property_value: start_wpb "9.0" xsd:float
property_value: end_wpb "10.0" xsd:float
property_value: start_dpb "63.0" xsd:float
property_value: end_dpb "70.0" xsd:float

[Term]
id: MmusDv:0000054
name: 10 weeks
namespace: mouse_developmental_stage
def: "2 month-old stage that refers to a mouse which is over 70 days and under 78 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "10.0" xsd:float
property_value: end_wpb "11.0" xsd:float
is_obsolete: true
consider: MmusDv:0000156

[Term]
id: MmusDv:0000156
name: 10-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 70 days and under 77 days old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000062 ! 2 month-old stage
relationship: immediately_preceded_by MmusDv:0000155 ! 9-week-old stage
property_value: start_wpb "10.0" xsd:float
property_value: end_wpb "11.0" xsd:float
property_value: start_dpb "70.0" xsd:float
property_value: end_dpb "77.0" xsd:float

[Term]
id: MmusDv:0000055
name: 11 weeks
namespace: mouse_developmental_stage
def: "2 month-old stage that refers to a mouse which is over 77 days and under 85 days old." [Bgee:curator "Bgee"]
property_value: start_wpb "11.0" xsd:float
property_value: end_wpb "12.0" xsd:float
is_obsolete: true
consider: MmusDv:0000157

[Term]
id: MmusDv:0000157
name: 11-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 77 days and under 84 days old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000062 ! 2 month-old stage
relationship: immediately_preceded_by MmusDv:0000156 ! 10-week-old stage
property_value: start_wpb "11.0" xsd:float
property_value: end_wpb "12.0" xsd:float
property_value: start_dpb "77.0" xsd:float
property_value: end_dpb "84.0" xsd:float

[Term]
id: MmusDv:0000137
name: 3-6 month-old mature stage
namespace: mouse_developmental_stage
def: "Mature stage that refers to a mouse which is over 3 and under 7 months old." [Bgee:curator "Bgee"]
comment: This stage is often used as the reference group for any age change in aging studies. Correlates to humans from 20 - 30 years old (see https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old).
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000153 ! young adult stage
relationship: immediately_preceded_by MmusDv:0000062 ! 2-month-old stage
property_value: start_mpb "3.0" xsd:float
property_value: end_mpb "7.0" xsd:float

[Term]
id: MmusDv:0000063
name: 3-month-old stage
namespace: mouse_developmental_stage
def: "Early adult stage that refers to a mouse which is over 3 and under 4 months old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000137 ! 3-6 month-old mature stage
relationship: immediately_preceded_by MmusDv:0000062 ! 2-month-old stage
property_value: start_wpb "12.0" xsd:float
property_value: end_wpb "16.0" xsd:float
property_value: start_mpb "3.0" xsd:float
property_value: end_mpb "4.0" xsd:float

[Term]
id: MmusDv:0000056
name: 12 weeks
namespace: mouse_developmental_stage
def: "3 month-old stage that refers to a mouse which is over 84 days and under 92 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "12.0" xsd:float
property_value: end_wpb "13.0" xsd:float
is_obsolete: true
consider: MmusDv:0000158

[Term]
id: MmusDv:0000158
name: 12-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 84 days and under 91 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000063 ! 3-month-old stage
relationship: immediately_preceded_by MmusDv:0000157 ! 11-week-old stage
property_value: start_wpb "12.0" xsd:float
property_value: end_wpb "13.0" xsd:float
property_value: start_dpb "84.0" xsd:float
property_value: end_dpb "91.0" xsd:float

[Term]
id: MmusDv:0000057
name: 13 weeks
namespace: mouse_developmental_stage
def: "3 month-old stage that refers to a mouse which is over 91 days and under 99 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "13.0" xsd:float
property_value: end_wpb "14.0" xsd:float
is_obsolete: true
consider: MmusDv:0000159

[Term]
id: MmusDv:0000159
name: 13-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 91 days and under 98 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000063 ! 3-month-old stage
relationship: immediately_preceded_by MmusDv:0000158 ! 12-week-old stage
property_value: start_wpb "13.0" xsd:float
property_value: end_wpb "14.0" xsd:float
property_value: start_dpb "91.0" xsd:float
property_value: end_dpb "98.0" xsd:float

[Term]
id: MmusDv:0000058
name: 14 weeks
namespace: mouse_developmental_stage
def: "3 month-old stage that refers to a mouse which is over 98 days and under 106 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "14.0" xsd:float
property_value: end_wpb "15.0" xsd:float
is_obsolete: true
consider: MmusDv:0000160

[Term]
id: MmusDv:0000160
name: 14-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 98 days and under 105 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000063 ! 3-month-old stage
relationship: immediately_preceded_by MmusDv:0000159 ! 13-week-old stage
property_value: start_wpb "14.0" xsd:float
property_value: end_wpb "15.0" xsd:float
property_value: start_dpb "98.0" xsd:float
property_value: end_dpb "105.0" xsd:float

[Term]
id: MmusDv:0000059
name: 15 weeks
namespace: mouse_developmental_stage
def: "3 month-old stage that refers to a mouse which is over 105 days and under 113 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "15.0" xsd:float
property_value: end_wpb "16.0" xsd:float
is_obsolete: true
consider: MmusDv:0000161

[Term]
id: MmusDv:0000161
name: 15-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 105 days and under 112 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000063 ! 3-month-old stage
relationship: immediately_preceded_by MmusDv:0000160 ! 14-week-old stage
property_value: start_wpb "15.0" xsd:float
property_value: end_wpb "16.0" xsd:float
property_value: start_dpb "105.0" xsd:float
property_value: end_dpb "112.0" xsd:float

[Term]
id: MmusDv:0000064
name: 4-month-old stage
namespace: mouse_developmental_stage
def: "Early adult stage that refers to a mouse which is over 4 and under 5 months old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000137 ! 3-6 month-old mature stage
relationship: immediately_preceded_by MmusDv:0000063 ! 3-month-old stage
property_value: start_wpb "16.0" xsd:float
property_value: end_wpb "21.0" xsd:float
property_value: start_mpb "4.0" xsd:float
property_value: end_mpb "5.0" xsd:float

[Term]
id: MmusDv:0000065
name: 16 weeks
namespace: mouse_developmental_stage
def: "4 month-old stage that refers to a mouse which is over 112 days and under 120 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "16.0" xsd:float
property_value: end_wpb "17.0" xsd:float
is_obsolete: true
consider: MmusDv:0000162

[Term]
id: MmusDv:0000162
name: 16-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 112 days and under 119 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000064 ! 4 month-old stage
relationship: immediately_preceded_by MmusDv:0000161 ! 15-week-old stage
property_value: start_wpb "16.0" xsd:float
property_value: end_wpb "17.0" xsd:float
property_value: start_dpb "112.0" xsd:float
property_value: end_dpb "119.0" xsd:float

[Term]
id: MmusDv:0000066
name: 17 weeks
namespace: mouse_developmental_stage
def: "4 month-old stage that refers to a mouse which is over 119 days and under 127 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "17.0" xsd:float
property_value: end_wpb "18.0" xsd:float
is_obsolete: true
consider: MmusDv:0000163

[Term]
id: MmusDv:0000163
name: 17-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 119 days and under 126 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000064 ! 4-month-old stage
relationship: immediately_preceded_by MmusDv:0000162 ! 16-week-old stage
property_value: start_wpb "17.0" xsd:float
property_value: end_wpb "18.0" xsd:float
property_value: start_dpb "119.0" xsd:float
property_value: end_dpb "126.0" xsd:float

[Term]
id: MmusDv:0000067
name: 18 weeks
namespace: mouse_developmental_stage
def: "4 month-old stage that refers to a mouse which is over 126 days and under 134 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "18.0" xsd:float
property_value: end_wpb "19.0" xsd:float
is_obsolete: true
consider: MmusDv:0000164

[Term]
id: MmusDv:0000164
name: 18-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 126 days and under 133 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000064 ! 4-month-old stage
relationship: immediately_preceded_by MmusDv:0000163 ! 17-week-old stage
property_value: start_wpb "18.0" xsd:float
property_value: end_wpb "19.0" xsd:float
property_value: start_dpb "126.0" xsd:float
property_value: end_dpb "133.0" xsd:float

[Term]
id: MmusDv:0000068
name: 19 weeks
namespace: mouse_developmental_stage
def: "4 month-old stage that refers to a mouse which is over 133 days and under 141 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "19.0" xsd:float
property_value: end_wpb "20.0" xsd:float
is_obsolete: true
consider: MmusDv:0000165

[Term]
id: MmusDv:0000165
name: 19-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 133 days and under 140 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000064 ! 4-month-old stage
relationship: immediately_preceded_by MmusDv:0000164 ! 18-week-old stage
property_value: start_wpb "19.0" xsd:float
property_value: end_wpb "20.0" xsd:float
property_value: start_dpb "133.0" xsd:float
property_value: end_dpb "140.0" xsd:float

[Term]
id: MmusDv:0000070
name: 20 weeks
namespace: mouse_developmental_stage
def: "4 month-old stage that refers to a mouse which is over 140 days and under 148 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "20.0" xsd:float
property_value: end_wpb "21.0" xsd:float
is_obsolete: true
consider: MmusDv:0000166

[Term]
id: MmusDv:0000166
name: 20-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 140 days and under 147 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000064 ! 4-month-old stage
relationship: immediately_preceded_by MmusDv:0000165 ! 19-week-old stage
property_value: start_wpb "20.0" xsd:float
property_value: end_wpb "21.0" xsd:float
property_value: start_dpb "140.0" xsd:float
property_value: end_dpb "147.0" xsd:float

[Term]
id: MmusDv:0000069
name: 5-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 5 and under 6 months old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000137 ! 3-6 month-old mature stage
relationship: immediately_preceded_by MmusDv:0000064 ! 4-month-old stage
property_value: start_wpb "21.0" xsd:float
property_value: end_wpb "25.0" xsd:float
property_value: start_mpb "5.0" xsd:float
property_value: end_mpb "6.0" xsd:float

[Term]
id: MmusDv:0000071
name: 21 weeks
namespace: mouse_developmental_stage
def: "5 month-old stage that refers to a mouse which is over 147 days and under 155 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "21.0" xsd:float
property_value: end_wpb "22.0" xsd:float
is_obsolete: true
consider: MmusDv:0000167

[Term]
id: MmusDv:0000167
name: 21-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 147 days and under 154 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000069 ! 5-month-old stage
relationship: immediately_preceded_by MmusDv:0000166 ! 20-week-old stage
property_value: start_wpb "21.0" xsd:float
property_value: end_wpb "22.0" xsd:float
property_value: start_dpb "147.0" xsd:float
property_value: end_dpb "154.0" xsd:float

[Term]
id: MmusDv:0000072
name: 22 weeks
namespace: mouse_developmental_stage
def: "5 month-old stage that refers to a mouse which is over 154 days and under 162 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "22.0" xsd:float
property_value: end_wpb "23.0" xsd:float
is_obsolete: true
consider: MmusDv:0000168

[Term]
id: MmusDv:0000168
name: 22-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 154 days and under 161 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000069 ! 5-month-old stage
relationship: immediately_preceded_by MmusDv:0000167 ! 21-week-old stage
property_value: start_wpb "22.0" xsd:float
property_value: end_wpb "23.0" xsd:float
property_value: start_dpb "154.0" xsd:float
property_value: end_dpb "161.0" xsd:float

[Term]
id: MmusDv:0000073
name: 23 weeks
namespace: mouse_developmental_stage
def: "5 month-old stage that refers to a mouse which is over 161 days and under 169 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "23.0" xsd:float
property_value: end_wpb "24.0" xsd:float
is_obsolete: true
consider: MmusDv:0000169

[Term]
id: MmusDv:0000169
name: 23-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 161 days and under 168 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000069 ! 5-month-old stage
relationship: immediately_preceded_by MmusDv:0000168 ! 22-week-old stage
property_value: start_wpb "23.0" xsd:float
property_value: end_wpb "24.0" xsd:float
property_value: start_dpb "161.0" xsd:float
property_value: end_dpb "168.0" xsd:float

[Term]
id: MmusDv:0000074
name: 24 weeks
namespace: mouse_developmental_stage
def: "5 month-old stage that refers to a mouse which is over 168 days and under 176 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "24.0" xsd:float
property_value: end_wpb "25.0" xsd:float
is_obsolete: true
consider: MmusDv:0000170

[Term]
id: MmusDv:0000170
name: 24-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 168 days and under 175 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000069 ! 5-month-old stage
relationship: immediately_preceded_by MmusDv:0000169 ! 23-week-old stage
property_value: start_wpb "24.0" xsd:float
property_value: end_wpb "25.0" xsd:float
property_value: start_dpb "168.0" xsd:float
property_value: end_dpb "175.0" xsd:float

[Term]
id: MmusDv:0000077
name: 6-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 6 and under 7 months old." [Bgee:curator "Bgee"]
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000137 ! 3-6 month-old mature stage
relationship: immediately_preceded_by MmusDv:0000069 ! 5-month-old stage
property_value: start_wpb "25.0" xsd:float
property_value: end_wpb "30.0" xsd:float
property_value: start_mpb "6.0" xsd:float
property_value: end_mpb "7.0" xsd:float

[Term]
id: MmusDv:0000098
name: 25 weeks
namespace: mouse_developmental_stage
def: "6 month-old stage that refers to a mouse which is over 175 days and under 183 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "25.0" xsd:float
property_value: end_wpb "26.0" xsd:float
is_obsolete: true
consider: MmusDv:0000171

[Term]
id: MmusDv:0000171
name: 25-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 175 days and under 182 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000077 ! 6-month-old stage
relationship: immediately_preceded_by MmusDv:0000170 ! 24-week-old stage
property_value: start_wpb "25.0" xsd:float
property_value: end_wpb "26.0" xsd:float
property_value: start_dpb "175.0" xsd:float
property_value: end_dpb "182.0" xsd:float

[Term]
id: MmusDv:0000099
name: 26 weeks
namespace: mouse_developmental_stage
def: "6 month-old stage that refers to a mouse which is over 182 days and under 190 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "26.0" xsd:float
property_value: end_wpb "27.0" xsd:float
is_obsolete: true
consider: MmusDv:0000172

[Term]
id: MmusDv:0000172
name: 26-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 182 days and under 189 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000077 ! 6-month-old stage
relationship: immediately_preceded_by MmusDv:0000171 ! 25-week-old stage
property_value: start_wpb "26.0" xsd:float
property_value: end_wpb "27.0" xsd:float
property_value: start_dpb "182.0" xsd:float
property_value: end_dpb "189.0" xsd:float

[Term]
id: MmusDv:0000100
name: 27 weeks
namespace: mouse_developmental_stage
def: "6 month-old stage that refers to a mouse which is over 189 days and under 197 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "27.0" xsd:float
property_value: end_wpb "28.0" xsd:float
is_obsolete: true
consider: MmusDv:0000173

[Term]
id: MmusDv:0000173
name: 27-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 189 days and under 196 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000077 ! 6-month-old stage
relationship: immediately_preceded_by MmusDv:0000172 ! 26-week-old stage
property_value: start_wpb "27.0" xsd:float
property_value: end_wpb "28.0" xsd:float
property_value: start_dpb "189.0" xsd:float
property_value: end_dpb "196.0" xsd:float

[Term]
id: MmusDv:0000101
name: 28 weeks
namespace: mouse_developmental_stage
def: "6 month-old stage that refers to a mouse which is over 196 days and under 204 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "28.0" xsd:float
property_value: end_wpb "29.0" xsd:float
is_obsolete: true
consider: MmusDv:0000174

[Term]
id: MmusDv:0000174
name: 28-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 196 days and under 203 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000077 ! 6-month-old stage
relationship: immediately_preceded_by MmusDv:0000173 ! 27-week-old stage
property_value: start_wpb "28.0" xsd:float
property_value: end_wpb "29.0" xsd:float
property_value: start_dpb "196.0" xsd:float
property_value: end_dpb "203.0" xsd:float

[Term]
id: MmusDv:0000102
name: 29 weeks
namespace: mouse_developmental_stage
def: "6 month-old stage that refers to a mouse which is over 203 days and under 211 days old." [Bgee:curator "Bgee"]
subset: granular_stage
property_value: start_wpb "29.0" xsd:float
property_value: end_wpb "30.0" xsd:float
is_obsolete: true
consider: MmusDv:0000175

[Term]
id: MmusDv:0000175
name: 29-week-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 203 days and under 210 days old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000077 ! 6-month-old stage
relationship: immediately_preceded_by MmusDv:0000174 ! 28-week-old stage
property_value: start_wpb "29.0" xsd:float
property_value: end_wpb "30.0" xsd:float
property_value: start_dpb "203.0" xsd:float
property_value: end_dpb "210.0" xsd:float

[Term]
id: MmusDv:0000097
name: late adult stage
namespace: mouse_developmental_stage
def: "Mature stage that refers to an adult mouse which is over 7 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD "adapted from"]
xref: UBERON:0007222
property_value: start_wpb "30.0" xsd:float
property_value: start_mpb "7.0" xsd:float
is_obsolete: true
consider: MmusDv:0000135
consider: MmusDv:0000134

[Term]
id: MmusDv:0000075
name: middle aged stage
namespace: mouse_developmental_stage
def: "Late adult stage that refers to a mouse which is over 7 and under 15 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD "adapted from"]
comment: This stage is commonly considered in the literature as the stage during which first evidence of loss of functional capability like hearing occurs in wild type mouse strain (see http://www.ncbi.nlm.nih.gov/pubmed/18259074).
property_value: start_wpb "30.0" xsd:float
property_value: start_mpb "7.0" xsd:float
property_value: end_mpb "15.0" xsd:float
is_obsolete: true
consider: MmusDv:0000078
consider: MmusDv:0000079
consider: MmusDv:0000080
consider: MmusDv:0000135

[Term]
id: MmusDv:0000078
name: 7-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 7 and under 8 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000153 ! young adult stage
relationship: immediately_preceded_by MmusDv:0000077 ! 6-month-old stage
property_value: start_wpb "30.0" xsd:float
property_value: start_mpb "7.0" xsd:float
property_value: end_mpb "8.0" xsd:float

[Term]
id: MmusDv:0000079
name: 8-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 8 and under 9 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000153 ! young adult stage
relationship: immediately_preceded_by MmusDv:0000078 ! 7-month-old stage
property_value: start_mpb "8.0" xsd:float
property_value: end_mpb "9.0" xsd:float

[Term]
id: MmusDv:0000080
name: 9-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 9 and under 10 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000153 ! young adult stage
relationship: immediately_preceded_by MmusDv:0000079 ! 8-month-old stage
property_value: start_mpb "9.0" xsd:float
property_value: end_mpb "10.0" xsd:float

[Term]
id: MmusDv:0000135
name: middle aged stage
namespace: mouse_developmental_stage
def: "Prime adult stage that refers to a mouse which is over 10 and under 18 months old." [Bgee:curator "Bgee"]
comment: Mice middle-aged group is used in the literature to investigate progressive age-related changes. For sake of consistency in age continuity, we adapt the age limits from https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old.
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000136 ! mouse prime adult stage
relationship: immediately_preceded_by MmusDv:0000080 ! 9-month-old stage
relationship: immediately_preceded_by MmusDv:0000153 ! young adult stage
property_value: start_mpb "10.0" xsd:float
property_value: end_mpb "18.0" xsd:float

[Term]
id: MmusDv:0000081
name: 10-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 10 and under 11 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000080 ! 9-month-old stage
property_value: start_mpb "10.0" xsd:float
property_value: end_mpb "11.0" xsd:float

[Term]
id: MmusDv:0000082
name: 11-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 11 and under 12 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000081 ! 10-month-old stage
property_value: start_mpb "11.0" xsd:float
property_value: end_mpb "12.0" xsd:float

[Term]
id: MmusDv:0000083
name: 12-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 12 and under 13 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000082 ! 11-month-old stage
property_value: start_mpb "12.0" xsd:float
property_value: end_mpb "13.0" xsd:float

[Term]
id: MmusDv:0000084
name: 13-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 13 and under 14 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000083 ! 12-month-old stage
property_value: start_mpb "13.0" xsd:float
property_value: end_mpb "14.0" xsd:float

[Term]
id: MmusDv:0000085
name: 14-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 14 and under 15 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000084 ! 13-month-old stage
property_value: start_mpb "14.0" xsd:float
property_value: end_mpb "15.0" xsd:float

[Term]
id: MmusDv:0000076
name: aged adult stage
namespace: mouse_developmental_stage
def: "Late adult stage that refers to a mouse which is over 15 months old." [http://research.jax.org/faculty/harrison/ger1vLifespan1.html#VD "adapted from"]
property_value: start_mpb "15.0" xsd:float
is_obsolete: true
consider: MmusDv:0000134

[Term]
id: MmusDv:0000086
name: 15-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 15 and under 16 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000085 ! 14-month-old stage
property_value: start_mpb "15.0" xsd:float
property_value: end_mpb "16.0" xsd:float

[Term]
id: MmusDv:0000087
name: 16-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 16 and under 17 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000086 ! 15-month-old stage
property_value: start_mpb "16.0" xsd:float
property_value: end_mpb "17.0" xsd:float

[Term]
id: MmusDv:0000088
name: 17-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 17 and under 18 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000135 ! middle aged stage
relationship: immediately_preceded_by MmusDv:0000087 ! 16-month-old stage
property_value: start_mpb "17.0" xsd:float
property_value: end_mpb "18.0" xsd:float

[Term]
id: MmusDv:0000134
name: late adult stage
namespace: mouse_developmental_stage
def: "Mature stage that refers to an adult mouse which is over 18 months old." [Bgee:curator "Bgee"]
comment: Mice from 18 months are considered as old and show presence of senescent changes in almost all biomarkers (see https://www.jax.org/news-and-insights/jax-blog/2017/november/when-are-mice-considered-old).
xref: UBERON:0007222
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000110 ! mouse mature stage
relationship: immediately_preceded_by MmusDv:0000088 ! 17-month-old stage
relationship: immediately_preceded_by MmusDv:0000136 ! prime adult stage
property_value: start_mpb "18.0" xsd:float

[Term]
id: MmusDv:0000089
name: 18-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 18 and under 19 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000134 ! mouse late adult stage
relationship: immediately_preceded_by MmusDv:0000088 ! 17-month-old stage
property_value: start_mpb "18.0" xsd:float
property_value: end_mpb "19.0" xsd:float

[Term]
id: MmusDv:0000090
name: 19-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 19 and under 20 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000134 ! mouse late adult stage
relationship: immediately_preceded_by MmusDv:0000089 ! 18-month-old stage
property_value: start_mpb "19.0" xsd:float
property_value: end_mpb "20.0" xsd:float

[Term]
id: MmusDv:0000091
name: 20-month-old stage and over
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 20 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000134 ! mouse late adult stage
relationship: immediately_preceded_by MmusDv:0000090 ! 19-month-old stage
property_value: start_mpb "20.0" xsd:float

[Term]
id: MmusDv:0000124
name: 20-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 20 and under 21 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000090 ! 19-month-old stage
property_value: start_mpb "20.0" xsd:float
property_value: end_mpb "21.0" xsd:float

[Term]
id: MmusDv:0000125
name: 21-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 21 and under 22 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000124 ! 20-month-old stage
property_value: start_mpb "21.0" xsd:float
property_value: end_mpb "22.0" xsd:float

[Term]
id: MmusDv:0000126
name: 22-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 22 and under 23 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000125 ! 21-month-old stage
property_value: start_mpb "22.0" xsd:float
property_value: end_mpb "23.0" xsd:float

[Term]
id: MmusDv:0000127
name: 23-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 23 and under 24 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000126 ! 22-month-old stage
property_value: start_mpb "23.0" xsd:float
property_value: end_mpb "24.0" xsd:float

[Term]
id: MmusDv:0000128
name: 24-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 24 and under 25 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000127 ! 23-month-old stage
property_value: start_mpb "24.0" xsd:float
property_value: end_mpb "25.0" xsd:float

[Term]
id: MmusDv:0000129
name: 25-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 25 and under 26 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000128 ! 24-month-old stage
property_value: start_mpb "25.0" xsd:float
property_value: end_mpb "26.0" xsd:float

[Term]
id: MmusDv:0000130
name: 26-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 26 and under 27 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000129 ! 25-month-old stage
property_value: start_mpb "26.0" xsd:float
property_value: end_mpb "27.0" xsd:float

[Term]
id: MmusDv:0000131
name: 27-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 27 and under 28 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000130 ! 26-month-old stage
property_value: start_mpb "27.0" xsd:float
property_value: end_mpb "28.0" xsd:float

[Term]
id: MmusDv:0000132
name: 28-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 28 and under 29 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000131 ! 27-month-old stage
property_value: start_mpb "28.0" xsd:float
property_value: end_mpb "29.0" xsd:float

[Term]
id: MmusDv:0000133
name: 29-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 29 and under 30 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000132 ! 28-month-old stage
property_value: start_mpb "29.0" xsd:float
property_value: end_mpb "30.0" xsd:float

[Term]
id: MmusDv:0000176
name: 30-month-old stage
namespace: mouse_developmental_stage
def: "Mouse stage that refers to a mouse which is over 30 and under 31 months old." [Bgee:curator "Bgee"]
subset: granular_stage
is_a: MmusDv:0000000 ! life cycle stage
relationship: part_of MmusDv:0000091 ! 20-month-old stage and over
relationship: immediately_preceded_by MmusDv:0000133 ! 29-month-old stage
property_value: start_mpb "30.0" xsd:float
property_value: end_mpb "31.0" xsd:float

[Typedef]
id: part_of
name: part of
xref: BFO:0000050
is_transitive: true

[Typedef]
id: preceded_by
name: preceded_by
def: "X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X)" []
xref: BFO:0000062
is_transitive: true

[Typedef]
id: immediately_preceded_by
name: immediately_preceded_by
def: "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)" []
is_a: preceded_by ! preceded_by
xref: RO:0002087 ! immediately_preceded_by

[Typedef]
id: has_unit
name: has unit
is_metadata_tag: true
comment: Used to associate a measurement property (e.g. days post fertilization) with a unit (e.g. days)

[Typedef]
id: has_start_time
name: has start time
is_metadata_tag: true

[Typedef]
id: has_end_time
name: has end time
is_metadata_tag: true

[Typedef]
id: start_dpc
name: start, days post coitum
def: "Count of number of days intervening between the start of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy "adapted from"]
is_metadata_tag: true
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000033 ! day
is_a: has_start_time

[Typedef]
id: end_dpc
name: end, days post coitum
def: "Count of number of days intervening between the end of the stage and the time of coitum, assuming that it takes place around midnight during a 7pm to 5am dark cycle (noon of the day on which the vaginal plug is found, the embryos are aged 0.5 days post coitum)." [http://php.med.unsw.edu.au/embryology/index.php?title=Mouse_Stages#Timed_Pregnancy "adapted from"]
is_metadata_tag: true
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent. 
property_value: has_unit UO:0000033 ! day
is_a: has_end_time

[Typedef]
id: start_wpb
name: start, weeks post birth
def: "Count of number of weeks intervening between the start of the stage and the time of birth according to a reference model. Note that the first week of post-birth development has the value of 0 for this property, and the period during which the mouse is one week old has the value 1." []
is_metadata_tag: true
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000034 ! week
is_a: has_start_time

[Typedef]
id: end_wpb
name: end, weeks post birth
def: "Count of number of weeks intervening between the end of the stage and the time of birth according to a reference model. Note that the first week of post-birth development has the value of 1 for this property, and the period during which the mouse is one week old has the value 2" []
is_metadata_tag: true
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000034 ! week
is_a: has_end_time

[Typedef]
id: start_mpb
name: start, months post birth
def: "Count of number of months intervening between the start of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 0 for this property, and the period during which the mouse is one month old has the value 1." []
is_metadata_tag: true
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000035 ! month
is_a: has_start_time

[Typedef]
id: end_mpb
name: end, months post birth
def: "Count of number of months intervening between the end of the stage and the time of birth according to a reference model. Note that the first month of post-birth development has the value of 1 for this property, and the period during which the mouse is one month old has the value 2" []
is_metadata_tag: true
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000035 ! month
is_a: has_end_time

[Typedef]
id: start_dpf
name: start, days post fertilization
def: "Count of number of days intervening between the start of the stage and the time of fertilization according to a reference model. Note that the first day of development has the value of 0 for this property." []
is_metadata_tag: true
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000033 ! day
is_a: has_start_time

[Typedef]
id: start_dpb
name: start, days post birth
def: "Count of number of days intervening between the start of the stage and the time of birth according to a reference model. Note that the first day of post-birth development has the value of 0 for this property, and the period during which the child is one day old has the value 1." []
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000033
is_metadata_tag: true

[Typedef]
id: end_dpb
name: end, days post birth
def: "Count of number of days intervening between the end of the stage and the time of birth according to a reference model. Note that the first day of post-birth development has the value of 1 for this property, and the period during which the child is one day old has the value 2" []
comment: This is a shortcut annotation that can be expanded to an OWL axiom, or to a set of OWL axioms. The exact translation has yet to be determined, and may be application-dependent.
property_value: has_unit UO:0000033
is_metadata_tag: true